title: [Influence of needling at yin-yang meridian points on cerebral glucose metabolism].
abstract: OBJECTIVE
  To study the different effect of needling at different meridian points (MP) on different cerebral functional regions by using positron emission tomography and cerebral function tracer 18F-fluorodeoxy glucose to observe the effect of electro-acupuncture (EA) stimulation at Yin MP or Yang MP on local cerebral glucose metabolism in 30 healthy volunteers.
  
  
  METHODS
  The thirty subjects were randomly divided into 2 groups, the 12 subjects in the Yang MP group treated by needling at Hegu (LI4), Quchi (LI11), Zusanli (St36) and Shangjuxu (St37), the 18 subjects in the Yin MP group treated by needling at Neiguan (Pc6), Chize (Lu5), Sanyinjiao (Sp6) and Yinlingquan (Sp9). All the needling was conducted at one side of body.
  
  
  RESULTS
  After needling at Yang MP, the cerebral glucose metabolism was elevated in bilateral cross region of frontal lobe and temporal lobe, parietal lobe, thalamus and basal ganglia, and in contralateral cerebellum and hippocampus. After needling at Yin MP, the cerebral glucose metabolism was lowered in bilateral cross region of frontal and temporal lobe, contralateral temporal lobe, cerebellum and thalamus, and was elevated in homolateral hippocampus and caudate nucleus.
  
  
  CONCLUSIONS
  Under physiological condition, the regulatory effects of acupuncture on central nervous system would be different when needling at different MP.
authors.affiliation: Affiliated Huashan Hospital to Fudan University, Shanghai 200040.
authors.forename: Jing-cheng
authors.initials: JC
authors.lastname: Dong
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.forename: Chuan-tao
authors.initials: CT
authors.lastname: Zuo
mesh_terms: D015669:Acupuncture Points; D000328:Adult; D001921:Brain / Q000378:metabolism*; D015671:Electroacupuncture; D005260:Female; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008297:Male; D016740:Meridians; D008875:Middle Aged; D011897:Random Allocation; D014055:Tomography, Emission-Computed
chemical_list: D005947:Glucose