[Effects of Hovenia dulcis Thunb on blood sugar and hepatic glycogen in diabetic mice].
OBJECTIVE
To observe the effects of Hovenia dulcis Thunb (HDT) on blood sugar and hepatic glycogen in diabetic mice.


METHODS
The diabetes model was established by alloxan and treated with different doses of HDT for 7 days, while the positive control group was treated with glibenclamide. Then the blood sugar and hepatic glycogen were measured.


RESULTS
The blood sugar of mice treated by HDT or glibenclamide significantly lower than diabetes model group. The hepatic glycogen in middle or low dose of HDT and glibenclamide groups was significantly increased.


CONCLUSIONS
HDT has effect on lowing blood sugar and may become an effective anti-diabetic herb.
Ji
Yang
Y
Drug and Instrument Inspect Institute of PLA, General Rear-Service Department, Beijing 100071.
Chen
Shan
S
Zhang
Kuirong
K
Wang
Wenjun
W
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D007004:Hypoglycemic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism*; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D027823:Rhamnaceae / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D008112:Liver Glycogen