title: Truncation artifact reduction in spectroscopic imaging using a dual-density spiral k-space trajectory.
abstract: Truncation artifacts arise in magnetic resonance spectroscopic imaging (MRSI) of the human brain due to limited coverage of k-space necessitated by low SNR of metabolite signal and limited scanning time. In proton MRSI of the head, intense extra-cranial lipid signals "bleed" into brain regions, thereby contaminating signals of metabolites therein. This work presents a data acquisition strategy for reducing truncation artifact based on extended k-space coverage achieved with a dual-SNR strategy. Using the fact that the SNR in k-space increases monotonically with sampling density, dual-SNR is achieved in an efficient manner with a dual-density spiral k-space trajectory that permits a smooth transition from high density to low density. The technique is demonstrated to be effective in reducing "bleeding" of extra-cranial lipid signals while preserving the SNR of metabolites in the brain.
authors.affiliation: The Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech/Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Shantanu
authors.initials: S
authors.lastname: Sarkar
authors.forename: Keith
authors.initials: K
authors.lastname: Heberlein
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Hu
mesh_terms: D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*