[Detecton of circulating antigen in sera from mice infected with Toxoplasma tachyzoites].
OBJECTIVE
To explore an assay method for the early diagnosis of Toxoplasma infection.


METHODS
Serum samples collected from three groups of mice infected experimentally with different doses of Toxoplasma trophozoites were detected for the presence of Toxoplasma circulating antigen by using fast ELISA.


RESULTS
Toxoplasma circulating antigen was detected on days 4, 4 and 3 after infection in light, moderate and heavy infection groups, respectively.


CONCLUSIONS
The level of circulating antigen was in parallel with the duration of infection. The determination of circulating antigen is useful in the early diagnosis of Toxoplasma infection.
Jin
W
W
Department of Pediatric Medicine, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025.
Li
Y
Y
Yu
S
S
Yang
H
H
Qian
Z
Z
D000818:Animals; D000953:Antigens, Protozoan / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D051379:Mice; D011817:Rabbits; D014122:Toxoplasma / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000175:diagnosis*
D000953:Antigens, Protozoan