title: Preoperative transcervical analgesia for laparoscopic sterilization with Filshie clips. A double blind randomized trial.
abstract: OBJECTIVE
  To evaluate the use of preoperative transcervical analgesia for reducing postoperative pain from laparoscopic sterilization with Filshie clips.
  
  
  METHODS
  A double blind, randomized, placebo-controlled trial.
  
  
  METHODS
  Gynecologic day-care clinic of Vejle Hospital, Vejle, Denmark.
  
  
  METHODS
  Seventy-eight healthy women were attending the public hospital requesting sterilization.
  
  
  METHODS
  Participants received bupivacaine 0.25% 20 mL or placebo normal saline 20 mL injected into the uterus, though the fallopian tubes and into the pelvis before tubal occlusion with Filshie clips.
  
  
  METHODS
  Post-operative visual analog pain score and request for analgesia were recorded.
  
  
  RESULTS
  At 30 min after clip application there was a non-significant reduction in pain-score on VAS. However, at 1, 2, 3 and 4 h median pain score on VAS was similar in both groups. Patients request for postoperative analgesia was similar in the two groups.
  
  
  CONCLUSIONS
  Preoperative transcervical perfusion of the uterus, fallopian tubes and into the pelvis did not reduce postoperative pain or request for analgesics after laparoscopic sterilization with Filshie clips.
authors.affiliation: Department of Obstetrics and Gynecology, Vejle Hospital, Vejle, Denmark. tine.schytte@dadlnet.dk
authors.forename: Tine
authors.initials: T
authors.lastname: Schytte
authors.forename: Jens Aage
authors.initials: JA
authors.lastname: Soerensen
authors.forename: Benedicte
authors.initials: B
authors.lastname: Hauge
authors.forename: Bent
authors.initials: B
authors.lastname: Andersen
mesh_terms: D000759:Adjuvants, Anesthesia / Q000627:therapeutic use; D000328:Adult; D000777:Anesthetics / Q000627:therapeutic use*; D002045:Bupivacaine / Q000627:therapeutic use*; D003627:Data Interpretation, Statistical; D004311:Double-Blind Method; D005187:Fallopian Tubes / Q000187:drug effects; D005260:Female; D006024:Glycopyrrolate / Q000627:therapeutic use; D006801:Humans; D010535:Laparoscopy; D010147:Pain Measurement / Q000379:methods; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control*; D011229:Preanesthetic Medication; D015742:Propofol / Q000627:therapeutic use; D018709:Statistics, Nonparametric; D013246:Sterilization, Tubal / Q000295:instrumentation / Q000379:methods*; D014599:Uterus / Q000187:drug effects
chemical_list: D000759:Adjuvants, Anesthesia; D000777:Anesthetics; D006024:Glycopyrrolate; D002045:Bupivacaine; D015742:Propofol