title: How do we achieve adequate therapy for severe infection?
authors.forename: George H
authors.initials: GH
authors.lastname: Karam
authors.forename: Michael S
authors.initials: MS
authors.lastname: Niederman
mesh_terms: D004352:Drug Resistance, Microbial; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000188:drug therapy