title: Adenosquamous carcinoma arising in Barrett's esophagus.
abstract: Primary adenocarcinoma of the esophagus is rare in Japan and, in most cases, arises from Barrett's esophagus epithelium. A 72-year-old man reporting heartburn and dysphagia and preoperatively diagnosed with adenosquamous carcinoma arising from Barrett's esophagus underwent thoracic esophagectomy and lymph node dissection in curative resection. Pathological diagnosis of the resected specimen showed adenosquamous carcinoma (coexistent adenocarcinoma and squamous cell carcinoma) invasive to the submucosal layer; metastasis was found in regional lymph nodes. Pathological staging was pT1bN1M0, stage II. Unfortunately, the man died of liver and lung metastasis 17 months postoperatively. To our knowledge, this rare case is only the fifth reported in the English literature on adenosquamous carcinoma arising from Barrett's esophagus.
authors.affiliation: Department of Oncological Science, Surgery II, Hasama-machi, Oita, 879-5593, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Noguchi
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Uchida
authors.forename: Shoichi
authors.initials: S
authors.lastname: Fumoto
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Wada
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Sato
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Takeno
mesh_terms: D000368:Aged; D001471:Barrett Esophagus / Q000150:complications* / Q000473:pathology / Q000601:surgery; D018196:Carcinoma, Adenosquamous / Q000209:etiology* / Q000556:secondary / Q000601:surgery; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016629:Esophagectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male