title: [Observation on the persistence period and transmission of residual microfilaremia with medium and higher density].
abstract: OBJECTIVE
  To explore the persistence period of medium and higher density of microfilaremia and its role in the transmission of filariasis in areas with filariasis basically eradicated.
  
  
  METHODS
  The residual microfilaremia was followed up and the population were regularly examined by thick blood film assay. Culex quinquefaciatus were dissected to determine the natural infection rate and density of filarial larvae. The filarial antibody levels were detected by using IFAT.
  
  
  RESULTS
  Two cases with medium and higher density of microfilaremia were found to be microfilaremia positive for twelve years. The natural infection rate and density of filarial larvae in Culex quinquefasciatus dropped down year by year, one case of new microfilaremia was found in the sixteenth year.
  
  
  CONCLUSIONS
  The persistence period of residual medium and higher density of microfilaremia lasted for more than twelve years. The individual residual medium and higher density of microfilaremia cases still possess the potential for transmission of filariasis.
authors.forename: J H
authors.initials: JH
authors.lastname: Duan
authors.forename: Z X
authors.initials: ZX
authors.lastname: Li
authors.forename: K R
authors.initials: KR
authors.lastname: Zhang
authors.forename: H Q
authors.initials: HQ
authors.lastname: Luo
authors.forename: X W
authors.initials: XW
authors.lastname: Zeng
authors.forename: D R
authors.initials: DR
authors.lastname: Zhang
mesh_terms: D000818:Animals; D003465:Culex / Q000469:parasitology; D005260:Female; D005368:Filariasis / Q000469:parasitology / Q000635:transmission*; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D008297:Male; D008842:Microfilariae; D014958:Wuchereria bancrofti