[Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function].
Puerariae isoflavone (500, 1000 mg/kg% x 7 d, p.o.) significantly lowered blood viscosity and platelet adhesion rate, inhibited thrombosis and ADP-induced platelet aggregation in rats, and showed obvious antagonism for platelet thrombosis in ADP-treated mice.
Yu
Z
Z
China Pharmaceutical University, Nanjing 210038.
Zhang
G
G
Zhao
H
H
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D007529:Isoflavones / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008517:Phytotherapy; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D029908:Pueraria / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013927:Thrombosis / Q000139:chemically induced / Q000517:prevention & control*
D004365:Drugs, Chinese Herbal; D007529:Isoflavones; D010975:Platelet Aggregation Inhibitors