title: [Influence of 89Sr on the cell immune function in patients with multiple bone metastases].
abstract: OBJECTIVE
  To investigate the influence of 89Sr on the cell immune function in patients with multiple bone metastases.
  
  
  METHODS
  Patients with multiple bone metastases were treated with in vivo radiation of 89Sr. The T cell subsets, NK cell activities, and lymphocyte transformation rate (LTR) of multiple bone metastases before and after the 89Sr treatment were measured.
  
  
  RESULTS
  With the palliation of the pain of the patients after the 89Sr treatment, the T cell subset level, NK cell activities, and LTR increased. There was no significant change in the patients with the pain.
  
  
  CONCLUSIONS
  Treating multiple bone metastases with 89Sr can improve the cell immune function of the patients to a certain extent.
authors.affiliation: Department of Nuclear Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Yong-gang
authors.initials: YG
authors.lastname: Wu
authors.forename: Qi-lin
authors.initials: QL
authors.lastname: Ma
authors.forename: Guo-feng
authors.initials: GF
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000276:immunology / Q000532:radiotherapy* / Q000556:secondary*; D001943:Breast Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy*; D013326:Strontium Radioisotopes / Q000627:therapeutic use*; D016176:T-Lymphocyte Subsets / Q000276:immunology
chemical_list: D013326:Strontium Radioisotopes