[Experimental study on anti-thrombus effect of different extracts from Semen Persicae].
OBJECTIVE
To observe the effects of anti-thrombus of different extracts from Semen Persicae and provide experimental basis for finding and defining effective fraction of Semen Persicae.


METHODS
The effects of different extracts from Semen Persicae on clotting time in mice, pulmonary embolism in mice and electro-irritate thrombosis in rats were observed.


RESULTS
Ethyl acetate extract from Semen Persicae could prolong clotting time in mice, markedly relieve respiratory difficult due to pulmonary embolism in mice induced by ADP-Na, obviously retard the generation of thrombosis induced by electrical injury of carotid artery in rats.


CONCLUSIONS
Ethyl acetate extract from Semen Persicae possesses evidently anti-thrombotic effect.
Wang
Ning
N
Department of Pharmacy, Anhui College of Traditional Chinese Medicine, Heifei 2300038.
Liu
Qingyun
Q
Peng
Daiyin
D
Wang
Lan
L
Wang
Shengxiang
S
D000818:Animals; D002341:Carotid Artery Thrombosis / Q000517:prevention & control*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D051379:Mice; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D027861:Prunus / Q000737:chemistry*; D011655:Pulmonary Embolism / Q000188:drug therapy; D051381:Rats; D017208:Rats, Wistar; D012639:Seeds / Q000737:chemistry; D014914:Whole Blood Coagulation Time
D004365:Drugs, Chinese Herbal; D005343:Fibrinolytic Agents