[Study on the effect of Rhizoma Curcuma Longa on gastrin receptor].
By the method of receptor combination, effects of the active constituents in Rhizoma Curcuma Longa and Radix Curcumae were studied. The results showed that Rhizoma Curcuma Longa probably include the excitant or antagonist of gastrin receptor. And the inhibitory intensity was shown as followed: parts of ethyl acetate > parts of methanol > parts of ether > parts of volatile oil, root tuber > rhizome.
Xiao
Xiaohe
X
Department of Pharmacy, 302 Hospital of PLA, Beijing 100039.
Zhao
Yanling
Y
Yuan
Hailong
H
Xia
Wenjuan
W
Zhao
Junning
J
Wang
Xiaodong
X
D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D030024:Curcuma / Q000737:chemistry; D003474:Curcumin / Q000302:isolation & purification / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005753:Gastric Mucosa / Q000378:metabolism; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D043887:Receptor, Cholecystokinin B / Q000037:antagonists & inhibitors / Q000187:drug effects*; D027343:Rhizome / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D043887:Receptor, Cholecystokinin B; D003474:Curcumin