title: Stenotrophomonas maltophilia endocarditis.
abstract: Stenotrophomonas maltophilia is a gram-negative bacillus that is increasingly associated with serious nosocomial infections, especially in immunocompromised patients; however, the occurrence of endocarditis due to this organism is rare. This report describes a case of S. maltophilia endocarditis associated with a central venous catheter. The literature on Stenotrophomonas endocarditis is reviewed. Given the high morbidity and mortality of these infections, early antibiotic therapy utilizing trimethoprim-sulfamethoxazole, along with a second agent and removal of prosthetic devices, is recommended.
authors.affiliation: Department of Internal Medicine, Infectious Diseases Division, Naval Medical Center San Diego, San Diego CA 92134, USA. nfcrum@nmcsd.med.navy.mil
authors.forename: Nancy F
authors.initials: NF
authors.lastname: Crum
authors.forename: Gregory C
authors.initials: GC
authors.lastname: Utz
authors.forename: Mark R
authors.initials: MR
authors.lastname: Wallace
mesh_terms: D004359:Drug Therapy, Combination; D004696:Endocarditis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced; D008875:Middle Aged; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*