Antibacterial compounds from the leaves of Acanthopanax senticosus.
Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate antibacterial activities against G (+) and G (-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 microg/ml.
Lee
Sanghyun
S
Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
Shin
Dong-Sun
DS
Oh
Ki-Bong
KB
Shin
Kuk Hyun
KH
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D028001:Eleutherococcus / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry
D000900:Anti-Bacterial Agents; D010936:Plant Extracts