title: Minimal model for genome evolution and growth.
abstract: Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random mutation but primarily grows by random segmental duplication. That genomes grew mostly by duplication is consistent with the observation that repeat sequences in all genomes are widespread and intragenomic and intergenomic homologous genes are preponderant across all life forms.
authors.affiliation: Department of Physics, National Central University, Chungli, Taiwan 320.
authors.forename: Li-Ching
authors.initials: LC
authors.lastname: Hsieh
authors.forename: Liaofu
authors.initials: L
authors.lastname: Luo
authors.forename: Fengmin
authors.initials: F
authors.lastname: Ji
authors.forename: H C
authors.initials: HC
authors.lastname: Lee
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D019143:Evolution, Molecular; D016680:Genome, Bacterial; D006193:Haemophilus influenzae / Q000235:genetics; D017017:Methanococcus / Q000235:genetics; D008957:Models, Genetic; D009343:Neisseria / Q000235:genetics
chemical_list: D004269:DNA, Bacterial