title: Antibacterial compounds from the leaves of Acanthopanax senticosus.
abstract: Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate antibacterial activities against G (+) and G (-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 microg/ml.
authors.affiliation: Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
authors.forename: Sanghyun
authors.initials: S
authors.lastname: Lee
authors.forename: Dong-Sun
authors.initials: DS
authors.lastname: Shin
authors.forename: Ki-Bong
authors.initials: KB
authors.lastname: Oh
authors.forename: Kuk Hyun
authors.initials: KH
authors.lastname: Shin
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D028001:Eleutherococcus / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts