title: [Preliminary study on ToRCH epidemic laws in Wuhan region].
abstract: OBJECTIVE
  To investigate the ToRCH epidemic law in Wuhan region.
  
  
  METHODS
  The ToRCH infection in the normal populations of Wuhan region was inspected through a whole year (from Mar. 1997 to Feb. 1998) by detecting the specific IgM antibodies to ToRCH in sera.
  
  
  RESULTS
  The results showed that in the whole year, the average positive rates of IgM aitibodies to Toxo, RuV, CMV and HSV were 5.8%, 7.5%, 4.2% and 4.9% respectively. Three characteristics of the ToRCH epidemic in the region were concluded: (1) The epidemic of RuV obviously changed with seasons. Its infection rates were the highest (8.5%, 19.5%, 14.0%) during spring (March, April and May). However, the changes of Toxo, CMV and HSV were not obvious with seasons; (2). The adult infections were mainly recessive, which had no apparent clinical symptoms; (3) The cross infections of the four pathogens were common, the cross-reaction rate of the surveyed year was 2.6%.
  
  
  CONCLUSIONS
  RuV infection of pregnant woman may result in congenital malformation of the emlbryo. Accoroding to the seasonal epidemic characteristics of RuV, women in pregnancy had better not to go to the public places during the sping seasons (March, April, May) as far as possible.
authors.affiliation: Institute of Virology, Hubei Academy of Medical Sciences, Wuhan 430079.
authors.forename: Z
authors.initials: Z
authors.lastname: Gong
authors.forename: L
authors.initials: L
authors.lastname: Luo
authors.forename: H
authors.initials: H
authors.lastname: Xiao
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D002681:China / Q000453:epidemiology; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000453:epidemiology*; D005260:Female; D006561:Herpes Simplex / Q000453:epidemiology*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D012409:Rubella / Q000453:epidemiology*; D018132:Rubivirus / Q000276:immunology; D016036:Seroepidemiologic Studies; D018139:Simplexvirus / Q000276:immunology; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000453:epidemiology*
chemical_list: D000913:Antibodies, Protozoan; D000914:Antibodies, Viral; D007075:Immunoglobulin M