title: [Gene polymorphisms in Uighur patients with Abnormal Savda].
abstract: OBJECTIVE
  To investigate gene polymorphisms in Uighur patients with Abnormal Savda.
  
  
  METHODS
  Polymorphisms of genomic fingerprints generated by arbitrarily primed PCR(AP-PCR) can be used for distinguishing between strains of almost any organism. The authors of this article applied the technique to the polymorphism analysis on the DNA of Uighur patients suffering from four kinds of Abnormal Savda (n=116), and on the DNA of a control group(n=50).
  
  
  RESULTS
  From the patients, 42 fragments were obtained, among them 27(64.2%) fragments did not show gene polymorphisms. On the 220-344 bp regions, the authors detected 6 AP-PCR products showing individual specificity.
  
  
  CONCLUSIONS
  The polymorphisms may serve as a molecular marker for gene diagnosis in the patients with Abnormal Savda.
authors.affiliation: Institute of Xinjiang Uighur Medicine, Urumqi, Xinjiang, PR China.
authors.forename: Upur
authors.initials: U
authors.lastname: Halmurat
authors.forename: Yimit
authors.initials: Y
authors.lastname: Askar
authors.forename: Sabit
authors.initials: S
authors.lastname: Ilhamjan
authors.forename: Kasim
authors.initials: K
authors.lastname: Obul
authors.forename: Sabir
authors.initials: S
authors.lastname: Roxangul
mesh_terms: D001249:Asthma / Q000175:diagnosis / Q000235:genetics; D004247:DNA / Q000235:genetics*; D016172:DNA Fingerprinting; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000235:genetics; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers; D004247:DNA