[Immune modulatory and therapeutical effect of shenqi tablet accessory therapy in treating recurrent genital herpes].
OBJECTIVE
To observe the immune modulatory and therapeutical effect of Shenqi tablet (SQT) in treating recurrent genital herpes.


METHODS
Sixty-three patients were randomly divided into two groups, the SQT group (34 cases) and the control group (29 cases). The immunologic function of patients was determined before and after treatment and the recurrence rate of two groups was compared.


RESULTS
In the SQT group after treatment, CD3, CD4 and CD4/CD8 ratio raised, CD8 percent lowered, serum interleukin 2 (SIL-2) and RBC-C3b raised and serum SIL-2 receptor lowered (all P < 0.05), while in the control group, the above-mentioned parameters were not changed significantly. Follow-up conducted 6 months after treatment showed that the recurrence rate in the SQT group was 26.5% (9 cases), which was lower than that in the control group (72.4%, 21 cases) significantly (P < 0.01).


CONCLUSIONS
SQT has immune modulatory effect in patients with recurrent genital herpes, it could reduce the recurrence rate.
Yu
J B
JB
Department of Dermatology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052.
Yin
G W
GW
He
Q B
QB
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D017252:CD3 Complex / Q000097:blood; D016516:CD4-CD8 Ratio; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006558:Herpes Genitalis / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007376:Interleukin-2 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D012008:Recurrence; D013607:Tablets
D000276:Adjuvants, Immunologic; D017252:CD3 Complex; D004365:Drugs, Chinese Herbal; D007376:Interleukin-2; D013607:Tablets