[Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China].
OBJECTIVE
The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.


METHODS
Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.


RESULTS
Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.


CONCLUSIONS
The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.
Li
Dong-na
DN
Department of Anatomy, the Third Military Medical University, Chongqing, PR China.
Ying
Da-jun
DJ
Ou
Cai-ying
CY
Chen
Lu
L
Zhou
Zhen-jian
ZJ
Fu
Sheng-miao
SM
D002681:China; D041322:Chromosomes, Human, Y / Q000235:genetics*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D005787:Gene Frequency; D014644:Genetic Variation; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D017422:Sequence Analysis, DNA
D004247:DNA