[Changes in immunogenesis organs after thyroidectomy and hormonal correction in an experiment].
Regulating effect of thyroid hormones on functions of organs of the immune system has been demonstrated in the experiment. Deficiency of thyroid hormones affects thymulin synthesis and morphofunctional status of immunogenesis organs. Combination of thymostimulin and thyroxin in the thyroidectomized animals, as compared to their separate use, is pathogenetically the most adequate correcting therapy aiming normalization of structural and functional disorders in the thymus and spleen. Prolonged reaction of tissual basophils saturated with heparin, indicated hormonal activation of blood anticoagulative system, and complex of the above hormones can be used for prevention of thromboembolic complications.
Bobro
L I
LI
Ukraine Institute of Oncology, 03022, Kiev.
Grinevich
Iu A
IuA
Bendiug
G D
GD
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology; D004359:Drug Therapy, Combination; D006493:Heparin / Q000494:pharmacology; D008407:Mast Cells / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D013949:Thymus Extracts / Q000627:therapeutic use*; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D013965:Thyroidectomy; D013974:Thyroxine / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000925:Anticoagulants; D013949:Thymus Extracts; C031407:thymostimulin; D006493:Heparin; D013974:Thyroxine