title: Coffee increases state anxiety in males but not in females.
abstract: Coffee, reproducing the conditions under which caffeine is normally ingested, containing 3, 75, 150 or 300 mg of caffeine was given to healthy male and female volunteers. 25-30 min after drinking the beverage, they completed the Spanish version of the state-trait anxiety inventory (STAI). The beverage increased state anxiety, in a dose-dependent manner, in males but not in females. This could be due to a lesser sensitivity of females to coffee.
authors.affiliation: Department of Psychobiology, Faculty of Psychology, University of Valencia, Valencia, Spain.
authors.forename: Paloma
authors.initials: P
authors.lastname: Botella
authors.forename: Andrés
authors.initials: A
authors.lastname: Parra
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000139:chemically induced*; D001794:Blood Pressure / Q000187:drug effects; D002110:Caffeine / Q000008:administration & dosage / Q000494:pharmacology; D000697:Central Nervous System Stimulants / Q000008:administration & dosage / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003069:Coffee; D004305:Dose-Response Relationship, Drug; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male
chemical_list: D000697:Central Nervous System Stimulants; D003069:Coffee; D002110:Caffeine