[Pharmacological study of cholagogic capsule].
Cholagogic capsule is mainly composed of Fiuctus Cardui, Mariae, Oleum Menthae Piperilae, Radix Currmae, olia taraxaci, Oleum Hyperici. It is shown that Cholagogic Capsule increase the rat's bile secretion significantly, but bile component is not influenced effectively, the retention jaundice models of which are created by ANIT isn't influenced effectively. It can reduce the mouse pinna swelling caused by dimethythenzene and depress the metatarsal swelling induced by carragenin, the antiinflammatory effect keeps for more than 4 h. It inhibits the contraction of gallbladder smooth musele of Guinea Pig caused by Ach. The results show that cholagogic Capsule increase bile secretion, antispasmodic and antiinflammatory effect. It is suggested the therapeutic effects of Cholagogic Capsule in sand-like calcul and acute chronic cholecystitis are related to the above pharmaological effects.
Tang
C
C
Guangdong College of Pharmacy, Guangzhou, 510224.
Zhang
C
C
He
Z
Z
Tang
Z
Z
Hong
J
J
Luo
X
X
Wu
Z
Z
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001646:Bile / Q000187:drug effects* / Q000378:metabolism; D002214:Capsules; D002764:Cholecystitis / Q000188:drug therapy* / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D007565:Jaundice / Q000188:drug therapy; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010276:Parasympatholytics / Q000494:pharmacology*; D008517:Phytotherapy; D051381:Rats
D000893:Anti-Inflammatory Agents; D002214:Capsules; D004365:Drugs, Chinese Herbal; D010276:Parasympatholytics