title: Clinical utility of urinary antigen detection for diagnosis of community-acquired, travel-associated, and nosocomial legionnaires' disease.
abstract: The clinical utility of Legionella urinary antigen assays for the diagnosis of Legionnaires' disease was assessed by using samples from 317 culture-proven cases. The sensitivities of the Binax enzyme immunoassay (EIA) and Biotest EIA were found to be 93.7 and 94.4% for travel-associated infection and 86.5 and 76.0% for community-acquired infection but only 44.2 and 45.7% for nosocomially acquired infection, respectively.
authors.affiliation: Institut Medizinische Mikrobiologie und Hygiene, Medizinische Fakultät TU Dresden, Dresden, Germany. Juergen.Helbig@mailbox.tu-dresden.de
authors.forename: Jürgen H
authors.initials: JH
authors.lastname: Helbig
authors.forename: Søren A
authors.initials: SA
authors.lastname: Uldum
authors.forename: Sverker
authors.initials: S
authors.lastname: Bernander
authors.forename: Paul Christian
authors.initials: PC
authors.lastname: Lück
authors.forename: Günther
authors.initials: G
authors.lastname: Wewalka
authors.forename: Bill
authors.initials: B
authors.lastname: Abraham
authors.forename: Valeria
authors.initials: V
authors.lastname: Gaia
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Harrison
mesh_terms: D000942:Antigens, Bacterial / Q000652:urine*; D017714:Community-Acquired Infections / Q000175:diagnosis*; D003428:Cross Infection / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007877:Legionnaires' Disease / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014195:Travel
chemical_list: D000942:Antigens, Bacterial