title: [Clinical observation on effect of yishen jiedu recipe in retarding the course of chronic renal failure].
abstract: OBJECTIVE
  To observe the effect of Yishen Jiedu Recipe (YSJDR) in retarding the course of chronic renal failure (CRF).
  
  
  METHODS
  Forty-five patients were divided into two groups, the 22 patients in Group A were treated with low-protein diet and blood pressure controlling therapy only, while the 23 patients in Group B were treated with additional YSJDR. The time (month) for doubling serum creatinine (SCr) level was taken to evaluate the speed of CRF progression.
  
  
  RESULTS
  In Group A, the time for SCr increased from 288.4 +/- 96.7 mumol/L to 586.3 +/- 251.3 mumol/L was 16.7 +/- 5.1 months, while in Group B the time for SCr increased from 291.2 +/- 101.2 mumol/L to 589.6 +/- 257.5 mumol/L was 28.2 +/- 8.7 months. Comparison between the two groups showed significant difference (P < 0.05).
  
  
  CONCLUSIONS
  On the basis of low-protein diet and blood pressure controlling therapy, the additional treatment of YSJDR could markedly retard the progression speed of CRF.
authors.affiliation: Guizhou Provincial Zunyi Hospital, Guizhou 563002.
authors.forename: Shuang-hua
authors.initials: SH
authors.lastname: Chen
authors.forename: Zun-pu
authors.initials: ZP
authors.lastname: Ban
authors.forename: Jian-lin
authors.initials: JL
authors.lastname: Cao
mesh_terms: D000328:Adult; D003404:Creatinine / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal; D003404:Creatinine