title: [Management of first trimester miscarriages].
abstract: BACKGROUND
  First trimester miscarriages complicating 15 to 20% of pregnancies, are the leading cause of gynecology emergencies.
  
  
  OBJECTIVE
  This review exhaustively summarized the French and English reports found on Medline data base about the management of first trimester miscarriage.
  
  
  RESULTS
  The treatment of reference remains surgical evacuation. It is generally used to avoid haemorrhage and intrauterine infection but is also required for women who wish an immediate termination of pregnancy. Recently, alternatives have been proposed, such as expectant management or medical treatment by misoprostol, to improve patient satisfaction and to reduce complications and costs generated by surgery. Expectant management allows to avoid curettage in most of incomplete miscarriages without any increase of the rate of complications or bleeding duration. Vaginal misoprostol allows complete expulsion in 70 to 90% of missed pregnancies without any increase of the rate of complications.
  
  
  CONCLUSIONS
  Today, we can propose to motivated and informed patients an alternative to surgical treatment but large randomized studies still are needed to assess benefits and risks for each method.
authors.affiliation: Service de Gynécologie Obstétrique et Médecine de la Reproduction, CHU, avenue Clémenceau, 14033 Caen.
authors.forename: G
authors.initials: G
authors.lastname: Beucher
authors.forename: T
authors.initials: T
authors.lastname: Beillat
authors.forename: M
authors.initials: M
authors.lastname: Dreyfus
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal; D000022:Abortion, Spontaneous / Q000628:therapy*; D005260:Female; D006801:Humans; D016595:Misoprostol; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016896:Treatment Outcome
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol