Cholesterol vehicle in experimental atherosclerosis 24: avocado oil.
OBJECTIVE
To determine atherogenicity of avocado oil relative to saturated (coconut oil), monounsaturated (olive oil) and polyunsaturated (corn oil) fats.


METHODS
New Zealand White rabbits were fed a semipurified diet containing 0.2% cholesterol and 14% fat for 90 days. They were then necropsied and severity of atherosclerosis was determined visually.


RESULTS
Coconut oil was the most atherogenic fat. Corn oil was only slightly less atherogenic than either olive or avocado oils. Percentage of serum HDL cholesterol was highest in the rabbits fed the two monounsaturated fats.


CONCLUSIONS
Avocado oil is of the same order of atherogenicity as corn oil and olive oil.
Kritchevsky
David
D
The Wistar Institute, Philadelphia, Pennsylvania 19104, USA. kritchevsky@mail.wistar.upenn.edu
Tepper
Shirley A
SA
Wright
Scott
S
Czarnecki
Susanne K
SK
Wilson
Thomas A
TA
Nicolosi
Robert J
RJ
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000473:pathology; D002784:Cholesterol / Q000097:blood; D000074263:Coconut Oil; D003314:Corn Oil; D004036:Diet, Atherogenic; D004195:Disease Models, Animal; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage; D008297:Male; D027421:Persea; D010938:Plant Oils / Q000008:administration & dosage*; D011817:Rabbits; D011897:Random Allocation; D012720:Severity of Illness Index
D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; D010938:Plant Oils; D003314:Corn Oil; D002784:Cholesterol; D000074263:Coconut Oil