Dietary conjugated linoleic acid alters hepatic lipid content and fatty acid composition in broiler chickens.
We examined the effect of dietary conjugated linoleic acid (CLA) on growth performance and liver composition in broiler chickens. Day-old male broiler chicks were assigned to receive a diet supplemented with corn oil (5%; n = 48) or CLA (5%; n = 48) for 21 d. Broilers fed CLA weighed less and grew at slower rates than broilers fed corn oil. Feed intake and feed conversion were higher for the corn-oil group than for the CLA dietary group. Hepatic lipid and triacylglycerol concentrations were significantly reduced by dietary CLA. The proportions of saturated fatty acids (SFA) in liver lipids increased, whereas those of monounsaturated fatty acids (MUFA) decreased with CLA supplementation. Although the total concentration of polyunsaturated fatty acids (PUFA) did not change with dietary treatment, the concentration of linoleic acid as a percentage of total methylated fatty acids decreased, and that of linolenic add increased in broilers fed CLA. The concentration of CLA isomers in liver lipids increased substantially with CLA feeding. The relative proportion of the c9,t11 CLA isomer in hepatic lipids was much higher than that of the t10,c12 or t9,t11 CLA isomers. These studies provide evidence that feeding CLA to broilers results in substantial reduction in liver fat accumulation and promotes CLA incorporation into hepatic lipid pools.
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Department of Animal Sciences, University of Florida, Gainesville, Florida 32611, USA. Badinga@animal.ufl.edu
Selberg
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D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002645:Chickens / Q000502:physiology*; D004032:Diet; D004435:Eating / Q000187:drug effects; D005227:Fatty Acids / Q000032:analysis*; D019787:Linoleic Acid / Q000008:administration & dosage* / Q000032:analysis; D008055:Lipids / Q000032:analysis*; D008099:Liver / Q000033:anatomy & histology / Q000737:chemistry / Q000187:drug effects*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D014280:Triglycerides / Q000032:analysis; D015430:Weight Gain / Q000187:drug effects
D005227:Fatty Acids; D008055:Lipids; D014280:Triglycerides; D019787:Linoleic Acid