title: Cimetidine therapy for epidermodysplasia verruciformis.
abstract: A 16-year-old boy with an 8-year history of multiple slightly keratotic papules on his face, trunk, and limbs, is described. On the basis of clinical features, histologic examination of 2 lesions and positivity for HPV 5, a diagnosis of epidermodysplasia verruciformis was made. Treatment with oral cimetidine (40 mg/kg per day) induced a marked improvement after 3 months of therapy, with no relapse at a 6-month follow-up.
authors.affiliation: Dermatology Clinic, University of Catania, Catania, Italy. cldermct@dimtel.nti.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Micali
authors.forename: Maria Rita
authors.initials: MR
authors.lastname: Nasca
authors.forename: Federica
authors.initials: F
authors.lastname: Dall'Oglio
authors.forename: Maria Letizia
authors.initials: ML
authors.lastname: Musumeci
mesh_terms: D000293:Adolescent; D002927:Cimetidine / Q000627:therapeutic use*; D004819:Epidermodysplasia Verruciformis / Q000188:drug therapy* / Q000473:pathology; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D006635:Histamine H2 Antagonists; D002927:Cimetidine