[The apoptosis of human gastric cancer cell induced by Acanthopanax giraldii Harms var Hispidus Hoo Polysaccharides in vitro].
OBJECTIVE
To investigate the effect of Acanthopanax Giraldii Harms Var Hispidus Hoo polysaccharides (AGP-I) on the human gastric cancer cell.


METHODS
DNA agarose gel electrophoresis and flow cytometry techniques were adopted.


RESULTS
After treatment with AGP-I, apoptotic peaks in cell cycle analysis and DNA ladder on the agarose gel were observed.


CONCLUSIONS
The results indicate that AGP-1 may inhibit cancer by inducing cancer cell apoptosis.
Lü
Xiaoying
X
Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University, Chengdu 610041, China.
Zeng
Lingfu
L
Cai
Ya'nan
Y
Li
You
Y
Liu
Xinhua
X
D000230:Adenocarcinoma / Q000473:pathology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D028001:Eleutherococcus / Q000737:chemistry*; D006801:Humans; D011134:Polysaccharides / Q000494:pharmacology*; D013274:Stomach Neoplasms / Q000473:pathology*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides