[Effects of n-butanol extract from Cortex Ilicis rotundae on blood pressure and heart rate in rate].
It was studied that effects of n-butanol extract from Cortex Ilicis Rotundae on blood pressure and heart rate in differedt state. Results showed that the drug elicited a sgnificant depressor effect on both normal pressure and artery pressure to rise for common carotid artery blocked in rats. Of the two latter decline of percent of blood presure and active time and slowing heart rate were more significan than the former. It was same depressor effect that injected the drug into duodenum but not act to hypotensive rats. These results suggested that the drug induce significantly depressor effect and slow heart rat with the exception of hypotension.
Dong
Y
Y
Guandong College of Pharmacy, Guangzhou 510224.
Liang
Y
Y
Luo
J
J
D020001:1-Butanol / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000494:pharmacology*; D029063:Aquifoliaceae / Q000737:chemistry*; D001794:Blood Pressure / Q000187:drug effects*; D017536:Carotid Artery, Common; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D008517:Phytotherapy; D024301:Plant Bark / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
D000893:Anti-Inflammatory Agents; D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; D020001:1-Butanol