Electrochemical investigations of cholesterol enriched glassy carbon supported thin lipid films.
The formation and study of stable cholesterol enriched thin lipid layers onto the surface of glassy carbon electrode is reported in this work. The method of formation relies on additional thinning of wetting films by electrostriction. Electrochemical techniques based on the concepts of impedance and voltammetry are used to explore the films' features. The impedance data reveal a substantial change of relaxation characteristics of the modified films. In this respect, opportunities for the evaluation of the films' stage based on the approximation with 'constant phase angle element' are discussed. The possible final structure of the films, as well as, their relevance for development of sensor elements are briefly viewed.
Karabaliev
Miroslav
M
Department of Physics and Biophysics, Faculty of Medicine, Trakia University, 11 Armeiska, Stara Zagora 6003, Bulgaria. mi_karabaliev@abv.bg
Kochev
Valery
V
D002244:Carbon; D002784:Cholesterol / Q000737:chemistry*; D017097:Electric Impedance; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D008055:Lipids / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry
D008055:Lipids; D010713:Phosphatidylcholines; D002244:Carbon; D002784:Cholesterol