Dermatological findings of human T lymphotropic virus type 1 (HTLV-I)-associated myelopathy/tropical spastic paraparesis.
Dermatological findings for patients with human T lymphotropic virus type 1(HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) were investigated and were compared with dermatological findings for a control group. Only xerosis, cutaneous candidiasis, and palmar erythema were significantly associated with HAM/TSP. Histopathological patterns of cutaneous lymphoma were seen in 25% of 32 patients who underwent biopsy, and, thus, the cutaneous alterations in HAM/TSP can be classified into nonspecific lesions, infectious lesions, immune-inflammatory-mediated lesions, and premalignant or malignant lesions.
Lenzi
Maria E R
ME
Reference Center for HTLV Infection and the Anatomopathology Laboratory, Evandro Chagas Clinical Research Institute-Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Cuzzi-Maya
Tullia
T
Oliveira
André L A
AL
Andrada-Serpa
Maria J
MJ
Araújo
Abelardo Q-C
AQ
D000328:Adult; D017677:Age Distribution; D005260:Female; D015490:HTLV-I Infections / Q000150:complications*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D008297:Male; D008875:Middle Aged; D015493:Paraparesis, Tropical Spastic / Q000150:complications*; D012871:Skin Diseases; D013118:Spinal Cord Diseases / Q000150:complications*