Pharmacological activities of Genistein, an isoflavone from soy (Glycine max): part II--anti-cholesterol activity, effects on osteoporosis & menopausal symptoms.
Phytoestrogens represent a family of plant compounds such as isoflavones, flavones and lignans. A wide range of commonly consumed foods contains appreciable amounts of different phytoestrogens such as isoflavones and lignans. Soy and its products are particularly good sources of isoflavones and lignans. The evidence reviewed here represents the beneficial effects of most potential and promising isoflavone, Genistein in various types of diseases such as osteoporosis, cardiovascular diseases, menopausal symptoms by accumulating evidence from molecular and cellular biology experiments, animal studies, and, to a limited extent, human clinical trials. This review suggests that phytoestrogens may potentially confer health benefits related to various diseases such as cardiovascular disorder, menopausal symptoms, and osteoporosis.
Suthar
A C
AC
Ajanta Pharma Ltd., Research Centre, Ajanta House, 98, Govt. Industrial Area, Charkop, Kandivali (West), Mumbai 400 067, India.
Banavalikar
M M
MM
Biyani
M K
MK
D000924:Anticholesteremic Agents / Q000494:pharmacology*; D005260:Female; D019833:Genistein / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008593:Menopause; D010024:Osteoporosis / Q000188:drug therapy*; D013025:Glycine max / Q000737:chemistry*
D000924:Anticholesteremic Agents; D019833:Genistein