The synthesis of a single enantiomer of a major alpha-mycolic acid of Mycobacterium tuberculosis.
We report a synthesis of a single enantiomer of a dicyclopropane containing mycolic acid from Mycobacterium tuberculosis; this method can be simply varied to modify the chain lengths or the absolute stereochemistry of either cyclopropane.
Al Dulayymi
Juma'a R
JR
Department of Chemistry, University of Wales, Bangor, UK LLS7 2UW.
Baird
Mark S
MS
Roberts
Evan
E
D003521:Cyclopropanes; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000737:chemistry*; D009171:Mycolic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D003521:Cyclopropanes; D009171:Mycolic Acids