title: [The histopathological observation and the clinical significance of invasion of pyriform sinus apex in pyriform sinus carcinoma].
abstract: OBJECTIVE
  To approach the clinical significance of pyriform sinus carcinoma invading to pyriform sinus apex.
  
  
  METHODS
  Forty-three cases of surgical specimens from total laryngectomy and partial hypopharyngectomy of pyriform sinus carcinoma were made with the organ subserial sectioning and pathological study.
  
  
  RESULTS
  Pyriform sinus apex is the inferior 1/3 region of pyriform sinus. If pyriform sinus carcinoma invades its apex, the cancerous tissue easely infiltrated the adjacent structure and organs.
  
  
  CONCLUSIONS
  The invasion of pyriform sinus apex is the beginning position and the most important sign of invading downward the tissue and surrounding organs in the inferior position of hypopharynx. When surgery treatment is performed, the total laryngectomy and hypopharyngectomy of ill hypopharynx is appropriate and necessary.
authors.affiliation: Liaoning Province Cancer Hospital, Shenyang 110042.
authors.forename: W
authors.initials: W
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Fei
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010610:Pharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D010611:Pharyngectomy