Environmental regulation of mutation rates at specific sites.
Recent studies on bacterial adaptation to stress suggest that bacteria can regulate the generation of mutations at specific sites in response to environmental conditions. Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous.
Massey
Ruth C
RC
Nuffield Dept of Clinical Laboratory Sciences, University of Oxford, Level 4, John Radcliffe Hospital, UK. ruth.massey@ndcls.ox.ac.uk
Buckling
Angus
A
D001419:Bacteria / Q000235:genetics*; D017753:Ecosystem; D004777:Environment; D005798:Genes, Bacterial; D009154:Mutation / Q000235:genetics*; D010641:Phenotype; D013997:Time Factors