[Effect of estrogen on dopamine release evoked by electric stimulation of central amygdaloid nucleus].
In vivo fast cyclic voltammetry (FCV) was used to investigate dopamine (DA) release from central amygdaloid nucleus (CAN) of ovariectomized (OVX), estrogen-treated and normal female rats. Radioimmunoassay was used to measure the serum concentration of estradiol (E(2)). DA release was significantly higher in OVX rats treated with estradiol benzoate (EB) as compared with controls. The DA release due to electric stimulation is dose-dependent on serum concentration of estradiol, suggesting that estrogen may play an important role in regulating DA release from CAN.
Xie
J X
JX
Department of Physiology, Medical College of Qingdao University, Qingdao 266021. jxiaxie@public.qd.sd.cn
Liu
B
B
D000679:Amygdala / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D004298:Dopamine / Q000378:metabolism*; D004558:Electric Stimulation; D004958:Estradiol / Q000031:analogs & derivatives* / Q000097:blood* / Q000494:pharmacology*; D005260:Female; D010052:Ovariectomy; D051381:Rats; D017208:Rats, Wistar
C074283:estradiol 3-benzoate; D004958:Estradiol; D004298:Dopamine