title: Obsessive compulsive behaviour in autism--towards an autistic-obsessive compulsive syndrome?
abstract: A portion of autistic patients exhibit compulsive-like behaviours. In addition it has been suggested that serotonin plays a major role in both obsessive compulsive disorder (OCD) and autistic disorder. Other neurohumors such as endogenous opioids and oxytocin have also been implicated in the two disorders. There is also some pharmacological overlap between the two disorders, as well as some similar neuroimaging studies. These similarities and overlaps have led us to propose a putative OCD-autistic disorder, which should be studied in greater detail.
authors.affiliation: Outpatient Department, Geha Psychiatric Hospital, P.O.B. 102, Petach Tikva 49100, Israel. bmruth@wisemail.weizmann.ac.il
authors.forename: R
authors.initials: R
authors.lastname: Gross-Isseroff
authors.forename: H
authors.initials: H
authors.lastname: Hermesh
authors.forename: A
authors.initials: A
authors.lastname: Weizman
mesh_terms: D001321:Autistic Disorder / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D001921:Brain / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009771:Obsessive-Compulsive Disorder / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D012701:Serotonin / Q000378:metabolism; D009626:Terminology as Topic
chemical_list: D012701:Serotonin