[Effect of gandou tablet I on neurological electrophysiology in patients of hepatolenticular degeneration].
OBJECTIVE
To observe the influence of Gandou Tablet I (GD I) on neurologic electrophysiology in patients of hepatolenticular degeneration (HLD).


METHODS
Vigilance-controlled electroencephalogram (VEEG), electromyogram (EMG) and brain-stem auditory evoked potential (BAEP) in 32 cases of HLD were examined before GD I treatment, and reexamined after 4 weeks of treatment in those with abnormal neurologic electrophysiology.


RESULTS
At the same time of clinical symptom improvement after treatment, the abnormal VEEG, EMG and BAEP also improved with the effective rate of 71.43%, 70% and 66.67% respectively, their constitutional ratio were different insignificantly, P > 0.05. The peak latency (PL) of III, V waves and interpeak latency (IPL) of I-III, III-V and I-V waves in patients before treatment were all greatly prolonged, compared with those in the healthy control group (P < 0.05 or 0.01), the IPL of III-V and I-V waves were markedly improved after treatment.


CONCLUSIONS
Neurologic electrophysiologic examination was valuable for complementary diagnosis and therapeutic effect evaluation of HLD. GD I could improve the abnormal neurologic electrophysiologic parameters.
Hu
Wen-bin
WB
Affiliated Hospital to Institute of Neurology, Anhui College of TCM, Hefei 230061.
Yang
Ren-min
RM
D000293:Adolescent; D000328:Adult; D002648:Child; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004569:Electroencephalography / Q000187:drug effects; D004576:Electromyography / Q000187:drug effects; D004594:Electrophysiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects*; D006527:Hepatolenticular Degeneration / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008517:Phytotherapy; D013607:Tablets
D004365:Drugs, Chinese Herbal; D013607:Tablets