[Applying pharmaceutical effect indexes to screen out the preparation technology of xiaobanxia added fuling granules].
After having adopted vomiting animal model created by filling stomach with cuprum sulfuricum and after having selected incubation period and vomiting index as our measuring and commenting indexes. We prepared decoction of Xiaobanxia added Fuling granules by applying orthogonal experimental method with four factors and three levels to proceed a preferable choice of extracting technology. The superior extracting technology became A2B3C2, namely: comminuting medicinal materials into coarse powder, for the first time, adding 9 times dosage of water and decocting for 45 minutes, for the second time, adding 5 times dosage of water and decocting for 30 minutes, condensing the filtrate to light paste (specific gravity 1.25-1.27, assaying at 25 centigrade), preparing decoction of Xiaobanxia added Fuling granules with a proportion as below:light paste:amylin:saccharose powder = 1:3:0.5.
Liu
W
W
Guiyang College of Traditional Chinese Medicine, 550002.
Feng
Y
Y
Zhang
X
X
Li
J
J
Qiu
D
D
D000818:Animals; D000932:Antiemetics / Q000008:administration & dosage* / Q000494:pharmacology; D010856:Columbidae; D019327:Copper Sulfate; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000302:isolation & purification / Q000627:therapeutic use; D005260:Female; D008297:Male; D030021:Pinellia / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D020072:Polyporales / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy
D000932:Antiemetics; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C473471:xiao-ban-xia-tang; D019327:Copper Sulfate