[Influence of 89Sr on the cell immune function in patients with multiple bone metastases].
OBJECTIVE
To investigate the influence of 89Sr on the cell immune function in patients with multiple bone metastases.


METHODS
Patients with multiple bone metastases were treated with in vivo radiation of 89Sr. The T cell subsets, NK cell activities, and lymphocyte transformation rate (LTR) of multiple bone metastases before and after the 89Sr treatment were measured.


RESULTS
With the palliation of the pain of the patients after the 89Sr treatment, the T cell subset level, NK cell activities, and LTR increased. There was no significant change in the patients with the pain.


CONCLUSIONS
Treating multiple bone metastases with 89Sr can improve the cell immune function of the patients to a certain extent.
Wu
Yong-gang
YG
Department of Nuclear Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Ma
Qi-lin
QL
Liu
Guo-feng
GF
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000276:immunology / Q000532:radiotherapy* / Q000556:secondary*; D001943:Breast Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy*; D013326:Strontium Radioisotopes / Q000627:therapeutic use*; D016176:T-Lymphocyte Subsets / Q000276:immunology
D013326:Strontium Radioisotopes