title: Moellerella wisconsensis: identification, natural antibiotic susceptibility and its dependency on the medium applied.
abstract: The present study establishes a data compilation on biochemical features and natural antibiotic susceptibilities of Moellerella wisconsensis strains. 17 moellerellae isolated from humans (n = 11), food (n = 5) and water (n = 1) were tested. Identification was carried out using two commercially available systems and conventional tests. MIC determinations of 74 antibiotics were performed applying a microdilution procedure in Cation-adjusted Mueller Hinton broth and IsoSensitest broth. M. wisconsensis was naturally sensitive to doxycycline, minocycline, all tested aminoglycosides, numerous beta-lactams, all fluoroquinolones, folate-pathway inhibitors, chloramphenicol and nitrofurantoin. Natural resistance was found with oxacillin, penicillin G, all tested macrolides, lincomycin, streptogramins, ketolides, glycopeptides, fusidic acid, linezolid and rifampicin. Medium-dependent differences in susceptibility affecting clinical assessment criteria were seen with tetracycline, clindamycin and fosfomycin. From the data of the present study it is possible that some moellerellae are misidentified as Klebsiella pneumoniae subsp. ozaenae.
authors.affiliation: Institute of Medical Microbiology and Immunology, Pharmaceutical Microbiology, University of Bonn, Bonn, Germany. ingostock@hotmail.com
authors.forename: Ingo
authors.initials: I
authors.lastname: Stock
authors.forename: Enevold
authors.initials: E
authors.lastname: Falsen
authors.forename: Bernd
authors.initials: B
authors.lastname: Wiedemann
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001431:Bacteriological Techniques; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000302:isolation & purification*; D006801:Humans; D008826:Microbial Sensitivity Tests; D012680:Sensitivity and Specificity
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media