title: Temporal and spatial coordination of exocytosis and endocytosis.
abstract: In secretory cells, exocytosis and compensatory endocytosis are tightly coupled membrane trafficking processes that control the surface area and composition of the plasma membrane. While exocytic and endocytic processes have been studied independently in great detail, at present there is much interest in understanding the mode of their coupling. This review discusses emerging insights into the coupling of these processes, both in the chemical synapses of neurons and in non-neuronal cells.
authors.affiliation: Leibniz Institute for Neurobiology, Department of Neurochemistry and Molecular Biology, Brenneckestr. 6, 39118 Magdeburg, Germany. gundelfinger@ifn-magdeburg.de
authors.forename: Eckart D
authors.initials: ED
authors.lastname: Gundelfinger
authors.forename: Michael M
authors.initials: MM
authors.lastname: Kessels
authors.forename: Britta
authors.initials: B
authors.lastname: Qualmann
mesh_terms: D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D009474:Neurons / Q000502:physiology; D021381:Protein Transport; D015398:Signal Transduction; D013569:Synapses
chemical_list: D002118:Calcium