Effect of Schistosoma japonicum infection on serum testosterone levels in mice.
OBJECTIVE
To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice.


METHODS
Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum.


RESULTS
The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls.


CONCLUSIONS
Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.
He
H B
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Hunan Institute of Parasitic Diseases, Yueyang 414000.
Ohta
N
N
Kawaguchi
H
H
D000818:Animals; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011863:Radioimmunoassay; D012554:Schistosomiasis japonica / Q000097:blood*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone