title: July 2002: 66-year-old female with a one-year history of progressive left proptosis.
abstract: The July 2002 Case of the Month (COM). This 66-year-old Caucasian female presented with gradually increasing protrusion of her left eye over a one-year period. She complained of increased tearing and foreign body sensation. The physical examination revealed a visual acuity of 20/20, normal color testing, full vision field with motility of her left eye limited in lateral gaze. Pupils were round, symmetric, with no afferent pupillary defect noted. On external examination, her left eye was grossly proptotic with resistance to retropulsion. She had 4 mm proptosis of the left eye. Computed tomography and MR imaging demonstrated a left retro-orbital mass with gadolinium enhancement and focal remodeling of orbital bones. She underwent surgical resection of tumor with a diagnosis of solitary fibrous tumor, and postoperatively she was symptom free. The histopathological differential diagnoses of spindle cell neoplasms of the orbit are discussed. Five months after surgery, no evidence of tumor recurrence was seen on neuroimaging and her vision was 20/20.
authors.affiliation: Division of Neuropathology, Vanderbilt University Medical Center, Nashville, Tenn., USA.
authors.forename: Xuemo
authors.initials: X
authors.lastname: Fan
authors.forename: Terry M
authors.initials: TM
authors.lastname: Semchyshyn
authors.forename: Louise A
authors.initials: LA
authors.lastname: Mawn
authors.forename: James B
authors.initials: JB
authors.lastname: Atkinson
authors.forename: James C
authors.initials: JC
authors.lastname: Anderson
authors.forename: Steven A
authors.initials: SA
authors.lastname: Toms
authors.forename: Mahlon D
authors.initials: MD
authors.lastname: Johnson
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology; D005260:Female; D005350:Fibroma / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006393:Hemangiopericytoma / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000473:pathology; D009442:Neurilemmoma / Q000473:pathology; D009918:Orbital Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D011859:Radiography