Synthesis of 1,2-diheteroatom-substituted alkenes via rhodium-catalyzed intramolecular hydrogen transfer.
While 1,2-diheteroatom-substituted alkenes represent useful synthetic building blocks, there are no simple, general procedures available for preparation of such compounds. We describe here a simple catalytic procedure based on rhodium C-H bond activation for the synthesis of diheteroatom alkenes of the type R(3)SiOCH=CHG (G = -OR, -NRR').
Diaz-Requejo
M Mar
MM
Department of Chemistry, University of North Carolina at Chapel Hill, CB # 3290 Venable Hall, Chapel Hill, North Carolina 27599-3290, USA.
DiSalvo
Darren
D
Brookhart
Maurice
M
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry
D000475:Alkenes; D000588:Amines; D004987:Ethers; D009942:Organometallic Compounds; D012821:Silanes; D006859:Hydrogen; D012238:Rhodium