title: Choroidal blood flow and arterial blood pressure.
abstract: OBJECTIVE
  Untreated hypertension is associated with ocular complications and is a risk factor for the development and progression of vascular ocular pathologies. We set out to investigate the association between systemic blood pressure and choroidal blood flow.
  
  
  METHODS
  All subjects were male non-smokers, who did not receive any medication and had normal or slightly elevated blood pressure (systolic blood pressure < or = 160 mmHg; diastolic blood pressure < or = 100 mmHg). The association between systemic blood pressure and fundus pulsation amplitude, a measure of pulsatile choroidal blood flow, was investigated in 318 volunteers. In addition, the association between systemic blood pressure and blood flow velocities in the posterior ciliary arteries supplying the choroid was investigated in these subjects.
  
  
  RESULTS
  Ocular fundus pulsation amplitude (r = 0.252; P < 0.001) and mean flow velocity in the posterior ciliary arteries (r = 0.346, P < 0.001) were significantly associated with mean arterial pressure. The correlation of ocular haemodynamic variables with systolic and diastolic blood pressure was in the same range.
  
  
  CONCLUSIONS
  Our data indicate a small, but significant increase in choroidal blood flow with increasing blood pressure.
authors.affiliation: Department of Ophthamology, Wäringer Gürtel, Vienna, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Polak
authors.forename: E
authors.initials: E
authors.lastname: Polska
authors.forename: A
authors.initials: A
authors.lastname: Luksch
authors.forename: G
authors.initials: G
authors.lastname: Dorner
authors.forename: G
authors.initials: G
authors.lastname: Fuchsjäger-Mayrl
authors.forename: O
authors.initials: O
authors.lastname: Findl
authors.forename: H-G
authors.initials: HG
authors.lastname: Eichler
authors.forename: M
authors.initials: M
authors.lastname: Wolzt
authors.forename: L
authors.initials: L
authors.lastname: Schmetterer
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000502:physiology*; D002829:Choroid / Q000098:blood supply*; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D011673:Pulsatile Flow / Q000502:physiology; D012044:Regression Analysis; D014463:Ultrasonography