Amphetamine-related acute myocardial infarction due to coronary artery spasm.
A 27-year-old man developed acute myocardial infarction after intravenous amphetamine use. A coronary angiogram showed plaques in the mid-portion of the left anterior descending artery which developed coronary artery spasm after administration of intracoronary ergonovine. The findings in this case suggest that these coronary artery plaques played a role in the endothelial dysfunction resulting from amphetamine use, and that induction of coronary arterial spasm was the likely mechanism of amphetamine-related acute myocardial infarction.
Hung
M J
MJ
Department of Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
Kuo
L T
LT
Cherng
W J
WJ
D000328:Adult; D019969:Amphetamine-Related Disorders / Q000150:complications*; D017023:Coronary Angiography / Q000379:methods; D003329:Coronary Vasospasm / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced*; D010960:Plasminogen Activators / Q000627:therapeutic use
D010960:Plasminogen Activators