[A case of Tinea capitis caused by Trichophyton tonsurans].
A 10-year-old Peruvian girl, living in Japan since 1996, visited our hospital in August 2000 complaining of alopecia which had been present on her scalp for one year. The bald areas appeared as multiple small, scattered, angular patches with indistinct margins. Follicular pustules, erythemic nodules and lymphadenopathy were also seen. In the culture of the affected hair, a tan surface with wiry undulations grew on Sabouraud's media. The colony reverse had reddish-brown central pigmentation. Slide cultured fungi produced great numbers of round and short club-shaped microconidia, hyphae and intercalary chlamydospores. These fungi showed the following characteristics: positive urease test, no pigment production on cornmeal agar and positive thiamine dependency. The restriction fragment length polymorphism pattern and the nucleotide sequences of ribosomal-DNA internal transcribed spacer region of the causative fungus was compatible with Trichophyton tonsurans. Daily administration of 125 mg of terbinafine resulted in a satisfactory response and the lesion healed almost completely.
Urano
Shoko
S
Department of Dermatology, Ensyu General Hospital, Shizuoka, Japan.
Shirai
Shigeko
S
Suzuki
Yoko
Y
Sugaya
Keiko
K
Takigawa
Masahiro
M
Mochizuki
Takashi
T
D000284:Administration, Oral; D001483:Base Sequence; D002648:Child; D004271:DNA, Fungal / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000235:genetics; D005260:Female; D006801:Humans; D009281:Naphthalenes / Q000008:administration & dosage; D012150:Polymorphism, Restriction Fragment Length; D000077291:Terbinafine; D014006:Tinea Capitis / Q000188:drug therapy / Q000382:microbiology*; D016896:Treatment Outcome; D014249:Trichophyton / Q000235:genetics / Q000302:isolation & purification*
D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D009281:Naphthalenes; D000077291:Terbinafine