title: Antimigraine drug consumption in Spain (1990-2000).
abstract: OBJECTIVE
  New marketed antimigraine drugs (triptans) are promising in the management of migraine pain. The impact of these new drugs on the overall consumption of the antimigraine drugs merits an analysis.
  
  
  METHODS
  The package units of antimigraine drugs, sold and reimbursed by the Spanish National Health System, are used for estimations. Data are presented as defined daily doses per 10,000 inhabitants/day.
  
  
  RESULTS
  During the 1990-2000 period, antimigraine drug utilization as a whole decreased by more than 25%; triptan use increased while ergot alkaloids' declined.
  
  
  CONCLUSIONS
  The pattern of antimigraine drug utilization in Spain has changed noticeably in accordance with recent recommendations.
authors.affiliation: Instituto de Farmacoepidemiología, Universidad de Valladolid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: García-del-Pozo
authors.forename: A
authors.initials: A
authors.lastname: Carvajal
authors.forename: C
authors.initials: C
authors.lastname: Grajal
authors.forename: E
authors.initials: E
authors.lastname: Vera
authors.forename: A
authors.initials: A
authors.lastname: del Pino
mesh_terms: D000322:Adrenergic Agonists / Q000627:therapeutic use*; D000700:Analgesics / Q000627:therapeutic use; D004338:Drug Combinations; D004363:Drug Utilization / Q000706:statistics & numerical data / Q000639:trends; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy* / Q000517:prevention & control*; D009313:National Health Programs / Q000706:statistics & numerical data; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use*; D013030:Spain; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*
chemical_list: D000322:Adrenergic Agonists; D000700:Analgesics; D004338:Drug Combinations; D017366:Serotonin Receptor Agonists; D014662:Vasoconstrictor Agents