Umbilical cord pseudocyst in a fetus with trisomy 18.
An umbilical cord pseudocyst was detected in the 28th week of gestation in a fetus complicated with growth restriction and polyhydramnios. The combination of cord pseudocysts, growth restriction, and polyhydramnios prompted us to perform a detailed ultrasonographic examination (gray scale and three-dimensional), which revealed the presence of micrognathia, overlapping fingers, and congenital heart defects, features characteristic of trisomy 18. Karyotyping confirmed a diagnosis of trisomy 18. After spontaneous labor onset, the infant was delivered at 31 weeks of gestation, and died soon after delivery. An umbilical cord pseudocyst is a good marker for the prenatal detection of trisomy 18.
Kuwata
T
T
Department of Obstetrics and Gynecology, Jichi Medical School, Kawachi-gun, Japan.
Matsubara
S
S
Izumi
A
A
Odagiri
K
K
Tsunoda
T
T
Watanabe
T
T
Taniguchi
N
N
Sato
I
I
D000328:Adult; D017809:Fatal Outcome; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications / Q000000981:diagnostic imaging / Q000235:genetics; D006801:Humans; D006831:Polyhydramnios / Q000150:complications / Q000000981:diagnostic imaging; D011247:Pregnancy; D014314:Trisomy; D016216:Ultrasonography, Prenatal; D014470:Umbilical Cord / Q000000981:diagnostic imaging / Q000473:pathology*; D014496:Urachal Cyst / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics*