[Pathogenesis and clinical classification of the malignant glaucoma].
OBJECTIVE
To study the pathogenesis of the malignant glaucoma and the basis for the clinical classification of malignant glaucoma.


METHODS
Twelve eyes with malignant glaucoma were examed by ultrasound biomicroscopy (UBM), type A and type B ocular ultrasounographer and other clinical ophthalmic tests and diagnostic therapy. The ocular anatomic structures of all 12 eyes were compared with those of the fellow eyes.


RESULTS
Ciliary block were confirmed in four of the twelve eyes (33.3%) with malignant glaucoma while the narrow and small anterior segment were found in the fellow eyes by UBM. Iris lens disphragm anterior displacement were found in the other eight of the twelve eyes (76.6%) and their ciliary bodies were deformed passively. The ciliary bodies and anterior segment of the fellow eyes of these eight eyes were anatomically normal. Diagnostic surgery was performed in seven of the twelve eyes and six cases with fluid existing in the vitreous cavity were identified.


CONCLUSIONS
According to our study, we suggest to classify malignant glaucoma into two tyges. One is ciliary block, which caused by ciliary block and concerned with the narrow and small structure of the anterior segment of eye. The other is lens iris block, which caused by iris lens diaphragm anterior displacement. Both types have the same pathophysiologic characteristics, such as, shallow anterior chamber, posterior chamber disappearance and aqueous humor misdirection to the vitreous cavity. But their pathogengesis may not be completely same.
Wang
N
N
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Zhou
W
W
Ouyang
J
J
Chen
X
X
Wu
J
J
D000328:Adult; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005901:Glaucoma / Q000145:classification* / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted; D014463:Ultrasonography