[Clinical study of treatment on chronic uric acid nephropathy by integrating Western and traditional Chinese medicine].
OBJECTIVE
To investigate the ameliorative effect on chronic uric acid nephropathy (CUAN) by integrating western and traditional Chinese medicine (IWTCM).


METHODS
The 136 CUAN patients were divided into two groups at random, the therapy group of 86 patients were treated by Chinese medicine and allopurinol, and the control group of 50 patients were treated only by allopurinol. The curative effect and the related index such as blood uric acid, renal function, urinary protein, microproteins, blood lipid and hyperviscosity were determined before and after being treated.


RESULTS
After three months treatment, the total effective rate in the therapy group (90.7%) was significantly higher (P < 0.01) than that of the control group (56%). The therapy group is also superior to the control group in improving renal function, lipid metabolism and hyperviscosity, decreasing blood uric acid, urinary protein, microproteins in evidence (P < 0.05, P < 0.01).


CONCLUSIONS
IWTCM can obviously improve the ameliorative effect on chronic uric acid nephropathy.
Wu
Xinlin
X
First Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510080.
Li
Junbiao
J
Mo
Suilin
S
Liu
Hongjian
H
Zhou
Ying
Y
Shen
Weizeng
W
D000328:Adult; D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use; D001809:Blood Viscosity; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D014527:Uric Acid / Q000097:blood*
D004365:Drugs, Chinese Herbal; D014527:Uric Acid; D000493:Allopurinol