[Conjunctival infection due to penicillium SP].
METHODS
We present a case of conjunctivitis in a diabetic patient in whom not improvement was observed after empiric treatment, and finally developed a conjunctival granuloma. Culture of the conjunctival exudate and histological examination of the conjunctival biopsy confirmed the infection by Penicillium sp. The antifungical treatment (local and systemic) improved signs and symtoms gradually.


CONCLUSIONS
Penicillium sp is an infrequent cause of conjunctival infection. This diagnosis should be considered when no response after usual therapy to conjunctivitis is obtained and should be confirmed by identification of the fungus in the lesions biopsed and cultured. Succesful management of ocular penicilliosis is achieved with both local and systemic antifungal treatment.
Miguélez
S
S
Fundación Hospital Manacor, Islas Baleares, España.
Obrador
P
P
Vila
J
J
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003231:Conjunctivitis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D010407:Penicillium / Q000302:isolation & purification*; D016896:Treatment Outcome
D000935:Antifungal Agents; D000666:Amphotericin B; D007654:Ketoconazole