title: Identification and characterization of the gerH operon of Bacillus anthracis endospores: a differential role for purine nucleosides in germination.
abstract: We identified a tri-cistronic operon, gerH, in Bacillus anthracis that is important for endospore germination triggered by two distinct germination response pathways termed inosine-His and purine-Ala. Together, the two pathways allow B. anthracis endospores a broader recognition of purines and amino acids that may be important for host-mediated germination.
authors.affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48104, USA.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Weiner
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Read
authors.forename: Philip C
authors.initials: PC
authors.lastname: Hanna
mesh_terms: D000409:Alanine / Q000494:pharmacology; D000596:Amino Acids / Q000494:pharmacology; D001408:Bacillus anthracis / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D007288:Inosine / Q000494:pharmacology; D009876:Operon; D011684:Purine Nucleosides / Q000494:pharmacology*; D013171:Spores, Bacterial / Q000235:genetics / Q000502:physiology
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D011684:Purine Nucleosides; D007288:Inosine; D000409:Alanine