[Studies on the chemical constituents of Lycianthes biflora].
OBJECTIVE
To study the chemical constituents of Lycianthes biflora.


METHODS
Column chromatography was used to separate the chemical constituents. IR, MS, 1HNMR, 13CNMR and 2D-NMR technique were used to determine the structures of the isolated constituents.


RESULTS
Five compounds were isolated from this plant. Their structures were identified to be bifloride A (1), N-trans-cinnamoyltyramine (2), liquiritigenin (3), N-trans-p-coumaroyloctopamine (4), 1-O-beta-D-glucopyranosyl-2-N-2'-hydroxypalmitoyl-sphinga-4- trans-8-trans-dienine (5).


CONCLUSIONS
Compounds 1 and 2 are new compounds, the others were isolated from this plant for the first time. Compound 2 showed inhibitory effects on P-388.
Yang
Guang-zhong
GZ
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China.
Zhao
Song
S
Li
Yuan-chao
YC
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D002934:Cinnamates / Q000737:chemistry / Q000302:isolation & purification*; D007941:Leukemia P388 / Q000473:pathology; D051379:Mice; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D019657:Solanaceae / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D014439:Tyramine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D000094162:Phytoalexins
D015107:4-Butyrolactone; D000972:Antineoplastic Agents, Phytogenic; D002934:Cinnamates; D014439:Tyramine; C479307:N-cinnamoyltyramine; D000094162:Phytoalexins; C479306:bifloride A