title: Cryptococcus neoformans myositis without dissemination.
abstract: We report a case of isolated cryptococcal myositis involving the paraspinal muscle without evidence of disseminated disease in a patient with a large B-cell lymphoma diagnosed at the time of presentation. Biopsy of the muscle involved grew a pure culture of Cryptococcus neoformans and periodic acid-Schiff staining showed numerous budding yeast consistent with Cryptococcus spp. The patient responded to systemic antifungal therapy with complete resolution of his infection. We also present a review of 5 previously published cases of cryptococcal myositis.
authors.affiliation: Department of Medicine, St John Hospital & Medical Center, Detroit, MI 48236, USA.
authors.forename: Mamta
authors.initials: M
authors.lastname: Sharma
authors.forename: Riad
authors.initials: R
authors.lastname: Khatib
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Jones
authors.forename: Mohamad G
authors.initials: MG
authors.lastname: Fakih
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009220:Myositis / Q000188:drug therapy / Q000469:parasitology*
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole