Precocious puberty secondary to topical testosterone exposure.
We report a case of pronounced virilization, including marked penile and pubic hair growth, accelerated height velocity and skeletal maturation, and increased muscle mass in a 2.67 year-old boy resulting from presumed inadvertent, long-term exposure to a topical testosterone cream being used by his father.
Franklin
Sherry Lynn
SL
Mattel Children's Hospital at UCLA, Los Angeles, CA, USA.
Geffner
Mitchell E
ME
D002675:Child, Preschool; D006197:Hair / Q000473:pathology; D006801:Humans; D008297:Male; D009824:Ointments; D010413:Penis / Q000473:pathology; D011629:Puberty, Precocious / Q000139:chemically induced* / Q000473:pathology; D013739:Testosterone / Q000008:administration & dosage / Q000009:adverse effects*
D009824:Ointments; D013739:Testosterone