[Effect of striatum destruction on the hypothalamo-pituitary-adrenal axis function in adrenalectomized rats].
The influence of the bilateral striatectomy on activation of the hypothalamus-pituitary-adrenal axis after unilateral adrenalectomy was investigated. Increasing of the intact adrenal gland's mass in striatectomized rats was less than in the control group. It was combined with decreasing of the production of corticosteroids by intact gland. Such disturbances were more obvious in rats with destruction of the dorsal striatum than the ventral one. These facts suggest the striatum participation, its dorsal zone in particular, in the processes of regulation of the hypothalamus-pituitary-adrenal axis.
Baturin
V A
VA
State Medical Academy, Stavropol, 355017, 310 Mira St., Russia.
Samokhvalova
T N
TN
D015062:11-Hydroxycorticosteroids / Q000032:analysis; D000311:Adrenal Glands / Q000737:chemistry / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D003342:Corpus Striatum / Q000502:physiology*; D004566:Electrodes; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D008297:Male; D009929:Organ Size; D010913:Pituitary-Adrenal System / Q000502:physiology*; D051381:Rats
D015062:11-Hydroxycorticosteroids