[The pharmacological studies of yifuzhixue pill].
OBJECTIVE
To investigate the pharmacological effect of Yifuzhixue Pill (YFZXP).


METHODS
PPT, RT, PT, platelet counts and platelet adhesive rate were examined after administration of YFZXP. In other hand, the functions of isolated rabbit's uteri were also examined to determine whether they were responsible to the administration of YFZXP.


RESULTS
YFZXP could enhance the intrinsic blood coagulating function and stimulate the contraction of smooth muscles of uterus including increasing the rhythms and strength. The stimulation effect of YFZXP on smooth muscles of uterus exhibited no selections between the uteri treated with or without estradiol. It was speculated that the increased intrinsic blood coagulating and uterus' contraction induced by YFZXP were contributed to its anti-bleeding effect in uterus.
Yan
Meiting
M
Qixing Pharmaceutical Co. Ltd., Guangzhou 510310.
Si
Jiangxi
J
Guan
Jinxia
J
D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry; D001777:Blood Coagulation / Q000187:drug effects; D029745:Codonopsis / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006490:Hemostatics / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010976:Platelet Count; D011817:Rabbits; D014590:Uterine Contraction / Q000187:drug effects*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D006490:Hemostatics