[Advances in research and development of tissue engineering].
OBJECTIVE
From the point of view of material science, the methods of tissue repair and defect reconstruct were discussed, including mesenchymal stem cells (MSCs), growth factors, gene therapy and tissue engineered tissue.


METHODS
The advances in tissue engineering technologies were introduced based on the recent literature.


RESULTS
Tissue engineering should solve the design and preparation of molecular scaffold, tissue vascularization and dynamic culture of cell on the scaffolds in vitro.


CONCLUSIONS
Biomaterials play an important role in the tissue engineering. They can be used as the matrices of MSCs, the delivery carrier of growth factor, the culture scaffold of cell in bioreactors and delivery carrier of gene encoding growth factors.
Yao
Kang-de
KD
Institute of Polymeric Materials, Tianjin University, Tianjin, P. R. China 300072.
Song
Xue-feng
XF
Liu
Wen-guang
WG
D001672:Biocompatible Materials; D001854:Bone Marrow Cells / Q000166:cytology; D018929:Cell Culture Techniques; D015316:Genetic Therapy; D006133:Growth Substances; D013234:Stem Cells / Q000166:cytology; D023822:Tissue Engineering / Q000379:methods
D001672:Biocompatible Materials; D006133:Growth Substances