title: [Study on the pharmacologic effect of propolis].
abstract: Pharmacologic effects of propolis were investigated in this article. The results suggested that propolis has pharmacologic functions in many aspects. It is a new-type medicine derived from animal in pharmacology and food both. To small mouse, propolis showed the functions of anti-fatigue and endurance to lack of oxygen. To high-blood-lipid-model mouse, it prevented increase of blood-mucus and blood lipid(TC, TG, LDL-C) (P < 0.05-0.01), but there were insignificant changes to red-blood-cell proportion (HCT) and high-density lipoprotein chelesteral (HDC-C). To small immunosuppessive-model mouse, propolis could strengthen macrophagocyte phagocytosis in the abdominal-cavity (P < 0.05), and increase the thymus-index (P < 0.05), but there were insignificant changes to the spleen-index. The LD50 > 7500 mg/kg to small mouse.
authors.affiliation: Department of Food Science and Engineering, Hangzhou University of Commerce, Hangzhou 310035.
authors.forename: J
authors.initials: J
authors.lastname: Luan
authors.forename: N
authors.initials: N
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Tian
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D001809:Blood Viscosity; D005221:Fatigue / Q000188:drug therapy; D005260:Female; D006949:Hyperlipidemias / Q000097:blood*; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000097:blood; D017737:Macrophages, Peritoneal / Q000276:immunology; D008297:Male; D008419:Materia Medica / Q000494:pharmacology*; D051379:Mice; D010587:Phagocytosis; D011429:Propolis / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000276:Adjuvants, Immunologic; D000960:Hypolipidemic Agents; D008055:Lipids; D008419:Materia Medica; D011429:Propolis