[Functional morphology of an organotypic liver culture exposed to the peptide livagen].
In this study the results of the tetrapeptide livagen effect on functional morphological characteristics have been produced. Under the data of the immunocytochemical and morphometrical analysis, tetrapeptide stimulates structural and functional homeostasis of cell populations in the liver culture. It was demonstrated that the main activity of investigated peptide had been directed to the stabilisation of morphological safety and reinforcement of the processes of cellular and intracellular forms of regeneration.
Riadnova
I Iu
IIu
St. Petersburg Institute of Bioregulation and Gerontology, 3, Dynamo pr., Saint Petersburg, Russia.
Filippov
S V
SV
Iuzhakov
V V
VV
D000818:Animals; D007150:Immunohistochemistry; D008099:Liver / Q000187:drug effects* / Q000502:physiology; D009841:Oligonucleotides / Q000494:pharmacology*; D009842:Oligopeptides; D009924:Organ Culture Techniques; D051381:Rats; D017208:Rats, Wistar
C473185:Livagen; D009841:Oligonucleotides; D009842:Oligopeptides