title: Acute pancreatitis--the current status in management.
abstract: Acute pancreatitis is a life-threatening inflammatory disorder of the pancreas. Currently, there is no effective pharmacological therapy available for this disorder. The management strategies remain supportive. Given the remarkable morbidity and mortality associated with acute pancreatitis, there is clearly a desperate need for effective novel therapies. This paper presents a review on the epidemiology, aetiology, pathogenesis and management of acute pancreatitis and highlights the need for the development of novel and more specific therapies to battle this disorder.
authors.affiliation: Division of Gastroenterology and Hepatology, Drexel University College of Medicine, 245 N 15th Street, Philadelphia, PA 19102, USA.
authors.forename: Jong H
authors.initials: JH
authors.lastname: Nam
authors.forename: Sreekant
authors.initials: S
authors.lastname: Murthy
mesh_terms: D000208:Acute Disease; D002769:Cholelithiasis / Q000150:complications; D003422:Critical Care; D016207:Cytokines / Q000037:antagonists & inhibitors; D006801:Humans; D009747:Nutritional Physiological Phenomena; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism; D010195:Pancreatitis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D011480:Protease Inhibitors / Q000627:therapeutic use
chemical_list: D016207:Cytokines; D011480:Protease Inhibitors