[Study on immunological pharmacology of keyin granule].
By intragastric keyin granule at the dosage of 1.0-4.0 g/kg.d[-1] for 7-10 days in mice, this drug can enhance the phagocytic function of the macrophages of peritoneal cavity, increase the index of spleen and the clearance rate of i.v. charcoal particles, obviously inhibit the formation of mouse-specific antibody and the delayed cutaneous hypersensitivity (DCH), recover the decrease of ANAE lymphocyte in periphery blood induced by cyclophosphamide. It can also improve the index of immunological organ of immunosuppression mice. These show the immunological regulative function of this drug.
Chen
Q
Q
Anhui Institute of Pharmacy, Hefei 230022.
Liang
Q
Q
Sun
B
B
D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000188:drug therapy* / Q000276:immunology; D018655:Lymphocyte Count; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D051379:Mice; D009929:Organ Size / Q000187:drug effects; D010587:Phagocytosis / Q000187:drug effects*; D008517:Phytotherapy
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal