title: Sesquiterpene lactones in a hairy root culture of Cichorium intybus.
abstract: A transformed root culture of Cichorium intybus L. (Asteraceae) was found to produce sesquiterpene lactones of guaiane and germacrane type. Lactucopicrin, 8-desoxylactucin and three sesquiterpene lactone glycosides: crepidiaside B, sonchuside A and ixerisoside D were isolated from the roots. The yield of 8-desoxylactucin reached 0.03 g l(-1) at the early stationary phase of the culture.
authors.affiliation: Department of Phytochemistry, Institute of Pharmacology, Polish Academy of Sciences, Smetna Street 12, 31-343 Kraków, Poland. malarzj@if-pan.krakow.pl
authors.forename: Janusz
authors.initials: J
authors.lastname: Malarz
authors.forename: Anna
authors.initials: A
authors.lastname: Stojakowska
authors.forename: Wanda
authors.initials: W
authors.lastname: Kisiel
mesh_terms: D018533:Biomass; D002478:Cells, Cultured; D018651:Cichorium intybus / Q000737:chemistry* / Q000254:growth & development; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification; D008958:Models, Molecular; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000382:microbiology; D018517:Plant Roots / Q000737:chemistry* / Q000254:growth & development; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D007783:Lactones; D010936:Plant Extracts; D012717:Sesquiterpenes