title: Economic burden and quality of life impairment increase with severity of PD.
abstract: OBJECTIVE
  To define the interrelationship between cost-of-illness, quality of life (QoL) and Parkinson's disease (PD) severity in a common patient management setting in Finland.Scope. Two hundred and sixty consecutive outpatients with idiopathic PD participated. UPDRS, motor fluctuations, QoL, and the use of health care resources were measured. Direct and indirect costs were calculated.
  
  
  CONCLUSIONS
  There is a strong relationship between QoL or cost-of-illness on the one hand, and severity of PD on the other. Treatment policies capable of reducing or delaying motor fluctuations would be expected to increase QoL and reduce some of the economic burden of PD.
authors.affiliation: Tampere University Hospital, Tampere, Finland. tapani.keranen@tyks.fi
authors.forename: T
authors.initials: T
authors.lastname: Keränen
authors.forename: S
authors.initials: S
authors.lastname: Kaakkola
authors.forename: K
authors.initials: K
authors.lastname: Sotaniemi
authors.forename: V
authors.initials: V
authors.lastname: Laulumaa
authors.forename: T
authors.initials: T
authors.lastname: Haapaniemi
authors.forename: T
authors.initials: T
authors.lastname: Jolma
authors.forename: H
authors.initials: H
authors.lastname: Kola
authors.forename: A
authors.initials: A
authors.lastname: Ylikoski
authors.forename: O
authors.initials: O
authors.lastname: Satomaa
authors.forename: J
authors.initials: J
authors.lastname: Kovanen
authors.forename: E
authors.initials: E
authors.lastname: Taimela
authors.forename: H
authors.initials: H
authors.lastname: Haapaniemi
authors.forename: H
authors.initials: H
authors.lastname: Turunen
authors.forename: A
authors.initials: A
authors.lastname: Takala
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000191:economics* / Q000503:physiopathology / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D018709:Statistics, Nonparametric