title: Improved systemic ventricular function after carvedilol administration in a patient with congenitally corrected transposition of the great arteries.
abstract: Congenitally corrected transposition of the great arteries (CCTGA) is associated with shortened survival due, at least in part, to progressive systolic dysfunction of the systemic ventricle. We report a substantial improvement in systemic ventricular function with carvedilol in a 63-year-old man with CCTGA.
authors.affiliation: Division of Cardiology, University of Colorado Hospital and Children's Hospital, University of Colorado Health Sciences Center, Denver, Colorado, USA. joAnn.lindenfield@uchsc.edu
authors.forename: JoAnn
authors.initials: J
authors.lastname: Lindenfeld
authors.forename: Karin
authors.initials: K
authors.lastname: Keller
authors.forename: David N
authors.initials: DN
authors.lastname: Campbell
authors.forename: Robert R
authors.initials: RR
authors.lastname: Wolfe
authors.forename: Robert A
authors.initials: RA
authors.lastname: Quaife
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D000077261:Carvedilol; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D013318:Stroke Volume / Q000187:drug effects / Q000502:physiology; D014188:Transposition of Great Vessels / Q000188:drug therapy / Q000503:physiopathology*; D018754:Ventricular Dysfunction / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol