Streptococcal antibodies among rural school children in Bangladesh.
The upper limit of normal values of group A streptococcal antibodies should be known for a population concerned because it is influenced by many local conditions. As yet the reference value of the these antibodies has not been determined by using a quantitative method among Bangladeshi children. We determined the reference value of anti-streptolysin O and anti-deoxyribonuclease B among 361 apparently healthy rural Bangladeshi primary school children (aged 5 to 14 years, mean 9.2 years). Anti-streptolysin O was measured by an auto-analyzer and antideoxyribonuclease B was measured by microtitre method. The geometric mean titres for the entire group was 241 IU/ml and 222 IU/ml for anti-streptolysin O and anti-deoxyribonuclease B respectively. The upper limit of normal values (80th percentile) was 390 and 340 for anti-streptolysin O and anti-deoxyribonuclease B, respectively. These limits should be of value to physicians, epidemiologists and clinical laboratory personnel as well.
Zaman
M M
MM
National Center for Control of Rheumatic Fever and Heart Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh.
Hassan
M M M
MM
Ahmed
J
J
Zareen
S
S
Jalil
M Q
MQ
Eshaque
N
N
Khanom
R
R
Khan
A
A
Osman
M
M
Jumma-A-Jalal
Rouf
M A
MA
Haque
K M H S S
KM
D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood*; D001426:Bacterial Proteins; D001459:Bangladesh; D002648:Child; D002675:Child, Preschool; D003851:Deoxyribonucleases / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012423:Rural Health; D013297:Streptococcus pyogenes / Q000276:immunology*; D013301:Streptolysins / Q000276:immunology
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D013301:Streptolysins; C025964:streptolysin O; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B