title: Mono- versus bidentate ligands in rhodium-catalyzed asymmetric hydrogenation. A comparative rate study.
abstract: [reaction: see text] Bidentate chiral phosphines are no longer essential for achieving a fast and highly enantioselective hydrogenation of alpha- or beta-dehydroamino acid derivatives. In particular, a readily accessible and stable monodentate phosphoramidite can be highly effective in these asymmetric hydrogenations.
authors.affiliation: Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Diego
authors.initials: D
authors.lastname: Peña
authors.forename: Adriaan J
authors.initials: AJ
authors.lastname: Minnaard
authors.forename: André H M
authors.initials: AH
authors.lastname: de Vries
authors.forename: Johannes G
authors.initials: JG
authors.lastname: de Vries
authors.forename: Ben L
authors.initials: BL
authors.lastname: Feringa