Formulation development of epidermal growth factor.
The information in this paper is presented to summarise various investigations in recent years to develop epidermal growth factor (EGF) delivery systems. EGF is a promising and well-characterised polypeptide that can be used in the treatment of various types of wounds and ulcers. Many approaches have been employed to deliver EGF as a stimulant for cellular activities involved in the processes of wound healing and tissue repair. Recently, emphasis is placed on the development of sustained or controlled delivery technology to optimise EGF delivery.
Lee
J
J
Department of Industrial and Physical Pharmacy, Purdue University, West Lafayette, USA. jaehwi@pharmacy.purdue.edu
D000818:Animals; D016503:Drug Delivery Systems; D004815:Epidermal Growth Factor / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D014456:Ulcer / Q000188:drug therapy; D014947:Wounds and Injuries / Q000188:drug therapy
D004815:Epidermal Growth Factor