title: Second-opinion magnetic resonance imaging for suspected fetal central nervous system abnormalities.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the relationship of magnetic resonance imaging and gestational age in the setting of fetuses with suspected abnormalities of the central nervous system that were detected by ultrasound scanning.
  
  
  METHODS
  Multiplanar magnetic resonance studies were performed in fetuses with suspected central nervous system abnormalities on ultrasound scanning. Magnetic resonance imaging was evaluated for its ability to provide additional information, change the diagnosis, or impact obstetric treatment. Patients were grouped by gestational age at the time of magnetic resonance imaging.
  
  
  RESULTS
  Magnetic resonance imaging provided additional information in 46 of 72 pregnancies (64%), changed the diagnosis in 20 of 72 pregnancies (28%), and potentially altered the timing or mode of delivery in 8 of 72 pregnancies (11%). Additional information increased with increasing gestational age groups (P =.03).
  
  
  CONCLUSIONS
  Magnetic resonance imaging provided additional information in two thirds of the fetuses with central nervous system abnormalities, which was significantly increased with increasing gestation. Antenatal treatment was influenced by magnetic resonance imaging in 11% of the cases.
authors.affiliation: Departments of Radiology, University of Texas Southwestern Medical Center, Dallas 75390, USA.
authors.forename: Diane M
authors.initials: DM
authors.lastname: Twickler
authors.forename: Kevin P
authors.initials: KP
authors.lastname: Magee
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Caire
authors.forename: Michael
authors.initials: M
authors.lastname: Zaretsky
authors.forename: James L
authors.initials: JL
authors.lastname: Fleckenstein
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Ramus
mesh_terms: D002490:Central Nervous System / Q000002:abnormalities* / Q000196:embryology*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005865:Gestational Age; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011295:Prenatal Care; D012017:Referral and Consultation