title: [Changes in the cardiac valvular apparatus in patients with end-stage chronic renal failure on long-term programmed hemodialysis].
abstract: OBJECTIVE
  To examine the specific features of development of cardiac valvular diseases, biochemical changes in the blood composition, and changes in the density of bone tissue in patients with chronic renal failure (CRF) treated with programmed hemodialysis.
  
  
  METHODS
  118 patients with CRF (Group 1 patients (n = 69) aged 18-40 years and Group 2 patients (n = 49) aged 55-73 years) were examined.
  
  
  RESULTS
  Mitral valvular prolapse or disease mainly developed in Group 1 patients having profound phophorous and calcium metabolic changes and significantly elevated concentrations of blood parathyroid hormone; developed aortic valvular disease and calcium salt-impregnated cardiac tissues were observed in Group 2 patients.
  
  
  CONCLUSIONS
  The revealed regularities occur in chronic renal failure regulated by programmed hemodialysis and they are risk factors for chronic heart failure in elderly patients in particular.
authors.forename: A P
authors.initials: AP
authors.lastname: Il'in
authors.forename: V F
authors.initials: VF
authors.lastname: Bogoiavlenskiĭ
authors.forename: R M
authors.initials: RM
authors.lastname: Gazizov
authors.forename: V V
authors.initials: VV
authors.lastname: Borisov
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001021:Aortic Valve / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D006349:Heart Valve Diseases / Q000378:metabolism / Q000503:physiopathology; D006351:Heart Valves / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000378:metabolism / Q000503:physiopathology; D006435:Renal Dialysis