title: Hydronium (cycloheptylammonio)methylene-1,1-bisphosphonate (hydronium incadronate).
abstract: The structure of the title compound, H(3)O(+).C(8)H(18)NO(6)P(2)(-), adopts a zwitterionic form containing an alkylammonium group, a hydronium ion, and two negatively charged phosphonate groups. The cycloheptyl side chain adopts a twist-chair conformation. The crystal packing is dominated by an extensive hydrogen-bonding network.
authors.affiliation: Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.
authors.forename: Erin M
authors.initials: EM
authors.lastname: Van Brussel
authors.forename: William L
authors.initials: WL
authors.lastname: Gossman
authors.forename: Scott R
authors.initials: SR
authors.lastname: Wilson
authors.forename: Eric
authors.initials: E
authors.lastname: Oldfield
mesh_terms: D001862:Bone Resorption / Q000188:drug therapy*; D018360:Crystallography, X-Ray; D004164:Diphosphonates / Q000737:chemistry*; D006860:Hydrogen Bonding; D006934:Hypercalcemia / Q000188:drug therapy; D008958:Models, Molecular; D013329:Structure-Activity Relationship
chemical_list: D004164:Diphosphonates; C071542:cimadronate