[Inhibiting effects of the ethanol-soluble extracts from the dried rhizoma of Garcinia oblougififolia on hepatitis B virus in vitro].
Comparing with Ara-Amp, the effects of the ethano-soluble extracts from the dried rhizoma of Garcinia oblougififolia Champ (GOC) on HBeAg and HBsAg expression in 2.2.15 cells, which came from transfected HepG2 cells with coloned HBV DNA, were studied. The results showed that the extracts of GOC had a marked inhibition effects on HBeAg adn HBsAg which expressed by 2.2.15 cells, the effective concentration was range from 195 to 780 micrograms/ml.
Yu
Z
Z
Research Institute of Liver Diseases, Guangzhou Air Force Hospital, 510602.
Chen
W
W
Zheng
Y
Y
D000998:Antiviral Agents / Q000494:pharmacology*; D029760:Garcinia; D056945:Hep G2 Cells; D006514:Hepatitis B Surface Antigens / Q000378:metabolism; D006513:Hepatitis B e Antigens / Q000378:metabolism; D006515:Hepatitis B virus / Q000187:drug effects*; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology*
D000998:Antiviral Agents; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D010936:Plant Extracts