title: Homoisoflavonoids from Ophiopogon japonicus Ker-Gawler.
abstract: From the ethyl acetate extract of the tuberous roots of Ophiopogon japonicus (Liliaceae) eight known and five new homoisoflavonoidal compounds were isolated. The new compounds are 5,7-dihydroxy-8-methoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one (1), 7-hydroxy-5,8-dimethoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one (2), 5,7-dihydroxy-6,8-dimethyl-3-(4'-hydroxy-3'-methoxybenzyl)chroman-4-one (3), 2,5,7-trihydroxy-6,8-dimethyl-3-(3',4'-methylenedioxybenzyl)chroman-4-one (4) and 2,5,7-trihydroxy-6,8-dimethyl-3-(4'-methoxybenzyl)chroman-4-one (5). Their structures have been elucidated by mass and NMR spectroscopy. Compounds 4 and 5 are the first isolated homoisoflavonoids with a hemiacetal function at position 2.
authors.affiliation: Institute of Chemistry, National Centre for Natural Sciences and Technology, Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam.
authors.forename: Nguyen Thi
authors.initials: NT
authors.lastname: Hoang Anh
authors.forename: Tran
authors.initials: T
authors.lastname: Van Sung
authors.forename: Andrea
authors.initials: A
authors.lastname: Porzel
authors.forename: Katrin
authors.initials: K
authors.lastname: Franke
authors.forename: Ludger A
authors.initials: LA
authors.lastname: Wessjohann
mesh_terms: D000080:Acetals / Q000737:chemistry; D002845:Chromatography / Q000379:methods; D007529:Isoflavones / Q000737:chemistry* / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D031441:Ophiopogon / Q000737:chemistry*; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000080:Acetals; D007529:Isoflavones