Ocular blood flow in healthy and primary open-angle glaucomatous eyes.
OBJECTIVE
To evaluate blood flow parameters in the ophthalmic artery, in the posterior ciliary arteries and in the central retinal artery in eyes with primary open-angle glaucoma.


METHODS
Hemodynamic parameters were evaluated by color Doppler imaging in 48 patients with primary open-angle glaucoma and 42 age-matched normal control subjects. Peak systolic velocity (Pv), end-diastolic velocity (Ev), and resistive index (RI) were calculated in the central retinal artery, short posterior ciliary arteries and the ophthalmic artery.


RESULTS
The analysis of the ocular blood flow velocities in the central retinal artery, short posterior ciliary arteries and the ophthalmic artery revealed a significant reduction in peak systolic velocity and end-diastolic velocity with an increase in resistive index in primary open-angle glaucoma compared with controls (p < 0.05).


CONCLUSIONS
Our data indicate primary open-angle glaucoma to be associated with a decreased flow velocity and increased resistive index in the ocular vasculature.
Birinci
Hakki
H
Department of Ophthalmology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. habirinci@yahoo.com
Danaci
Murat
M
Oge
Ihsan
I
Erkan
N Dilek
ND
D001783:Blood Flow Velocity; D002200:Capillary Resistance / Q000502:physiology; D019842:Ciliary Arteries / Q000503:physiopathology; D005123:Eye / Q000503:physiopathology; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000503:physiopathology; D012039:Regional Blood Flow / Q000502:physiology*; D012161:Retinal Artery / Q000503:physiopathology; D018615:Ultrasonography, Doppler, Color / Q000379:methods