Kava kava may cause irreversible liver damage.
D016907:Adverse Drug Reaction Reporting Systems / Q000458:organization & administration*; D000529:Complementary Therapies / Q000009:adverse effects; D004346:Drug Information Services / Q000458:organization & administration; D029001:Herbal Medicine; D006801:Humans; D020901:Kava / Q000009:adverse effects*; D017093:Liver Failure / Q000139:chemically induced* / Q000453:epidemiology; D016488:Medicine, African Traditional; D012042:Registries; D013019:South Africa / Q000453:epidemiology