Pulmonary eosinophilia following lung transplantation for sarcoidosis in two patients.
Pulmonary eosinophilia is an uncommon problem in lung transplant recipients. We report the unique occurrence of two cases of pulmonary eosinophilia in pulmonary allografts for sarcoidosis. Both patients rapidly acquired bronchiolitis obliterans syndrome (BOS) after resolution of pulmonary eosinophilia. It is known that peripheral eosinophilia is a marker for pulmonary allograft rejection, but its potential in the pathogenesis of BOS is unclear.
Gerhardt
Susan G
SG
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
Tuder
Rubin M
RM
Girgis
Reda E
RE
Yang
Stephen C
SC
Conte
John V
JV
Orens
Jonathan B
JB
D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006084:Graft Rejection / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D016040:Lung Transplantation / Q000473:pathology; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D011657:Pulmonary Eosinophilia / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D017565:Sarcoidosis, Pulmonary / Q000473:pathology / Q000601:surgery*; D014184:Transplantation, Homologous