Knowledge of antiretroviral regimen dosing and adherence: a longitudinal study.
In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.
Miller
Loren G
LG
Division of Infectious Diseases, Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance 90502, USA. lgmiller@ucla.edu
Liu
Honghu
H
Hays
Ron D
RD
Golin
Carol E
CE
Ye
Zhishen
Z
Beck
C Keith
CK
Kaplan
Andrew H
AH
Wenger
Neil S
NS
D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010349:Patient Compliance
D019380:Anti-HIV Agents