[Evaluation of the effect of streptomycin perfusion of the labyrinth in the treatment of Meniere's disease and endolymphatic hydrops].
OBJECTIVE
To investigate the clinical effect of streptomycin perfusion of the labyrinth (SPL) in the treatment of Meniere's disease.


METHODS
13 patients with Meniere's disease and 3 patients with delayed endolymphatic hydrops (DEH) underwent SPL. The follow-up time was between 5 and 7 years (average 6.3 years).


RESULTS
Vertigo was completely controlled in 9 patients, substantialy controlled in 4, limitedly controlled in 2 and not controlled in 1. Hearing was improved in 1 patients, stabilized in 5 and worse in 10. Tinnitus was improved in 3 patients, stabilized in 5 and worse in 8.


CONCLUSIONS
SPL is a safe and effective method in the treatment of Meniere's disease and DEH, but the hearing may be insulted and tinnitus may be worse in some patients.
Peng
A Q
AQ
Department of Otolaryngology, Second Affiliatd Hospital of Hunan Medical University, Changsha 410011.
Lu
Y D
YD
Ren
J H
JH
Chen
Z
Z
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D010478:Chemotherapy, Cancer, Regional Perfusion; D007758:Ear, Inner; D018159:Endolymphatic Hydrops / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000188:drug therapy*; D008875:Middle Aged; D013307:Streptomycin / Q000008:administration & dosage*
D000900:Anti-Bacterial Agents; D013307:Streptomycin