title: A comparison of lithium dilution cardiac output measurements made using central and antecubital venous injection of lithium chloride.
abstract: OBJECTIVE
  We have previously described an indicator dilution technique of measuring cardiac output in which lithium chloride is injected as a bolus via a central venous catheter and cardiac output derived from the arterial lithium dilution curve recorded from a lithium-selective electrode, which we have developed for this purpose. It would be an advantage if the lithium could be injected via the basilic vein (in the antecubital fossa) in those patients who do not need central venous catheterisation for other reasons. We have therefore compared cardiac output measurements made using these two routes of lithium chloride administration.
  
  
  METHODS
  Lithium dilution cardiac output was measured 10 times in each of 10 patients, injecting the lithium chloride alternately via the basilic or central venous catheter.
  
  
  RESULTS
  The mean difference was 0.8 +/- 5.2% (SD) (range -8.5 to +7.0%) over a range of cardiac output of 4.5-13 l/min.
  
  
  CONCLUSIONS
  Injection of lithium chloride via the basilic vein in the antecubital fossa allows accurate lithium dilution cardiac output measurements to be made in patients who do not have central venous catheters in place.
authors.affiliation: Shackleton Department of Anaesthetics, Southampton General Hospital, Southampton, SO16 6YD, UK.
authors.forename: M M
authors.initials: MM
authors.lastname: Jonas
authors.forename: F E
authors.initials: FE
authors.lastname: Kelly
authors.forename: R A
authors.initials: RA
authors.lastname: Linton
authors.forename: D M
authors.initials: DM
authors.lastname: Band
authors.forename: T K
authors.initials: TK
authors.lastname: O'Brien
authors.forename: N W
authors.initials: NW
authors.lastname: Linton
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D002302:Cardiac Output; D002405:Catheterization, Central Venous; D006801:Humans; D007201:Indicator Dilution Techniques; D007275:Injections, Intravenous; D018021:Lithium Chloride / Q000008:administration & dosage*
chemical_list: D000276:Adjuvants, Immunologic; D018021:Lithium Chloride