Clinical study of a spacer to help prevent osteoradionecrosis resulting from brachytherapy for tongue cancer.
OBJECTIVE
We sought to describe a simple method to construct a spacer and to evaluate with the use of computed tomography the spacer's effectiveness in preventing osteoradionecrosis of the mandible.


METHODS
Fifty-three patients with oral tongue cancers who were treated by means of interstitial brachytherapy were included in this study. Patients underwent a computed tomography examination immediately after the implantation of radioactive sources, with the spacers in place. Distances between the radioactive sources and the lingual surfaces of the mandible were measured on transverse computed tomographs and were evaluated in terms of the development of osteoradionecrosis in the mandible.


RESULTS
Statistically significant differences in the frequency of osteoradionecrosis were observed between patients who had received spacers equal to or thicker than 5 mm and those who had received spacers less than 5 mm thick.


CONCLUSIONS
A spacer should have a minimum thickness of 5 mm on its lingual flange to prevent the development of osteoradionecrosis of the mandible.
Obinata
Kenichi
K
Division of Oral and Maxillofacial Disorders, Hokkaido University Dental Hospital, Sapporo, Japan. obinata@den.hokudai.ac.jp
Ohmori
Keiichi
K
Tuchiya
Kazuhiko
K
Nishioka
Takeshi
T
Shirato
Hiroki
H
Nakamura
Motoyasu
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000009:adverse effects*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging; D008336:Mandibular Diseases / Q000209:etiology / Q000517:prevention & control*; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000209:etiology / Q000517:prevention & control*; D011482:Protective Devices; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014062:Tongue Neoplasms / Q000532:radiotherapy*