title: [Hypoglycemic effect of saponin from Tribulus terrestris].
abstract: OBJECTIVE
  To study the hypoglycemic effect of saponin from Tribulus terrestris L.
  
  
  METHODS
  Alloxan was used to establish the diabetic model in mice. Phenformin Hydrochlride Tables was used as the positive control. The level of glucose, triglyceride, cholesterol and SOD in serum were determined.
  
  
  RESULTS
  The level of serum glucose could be significantly reduced by saponin from Tribulus terrestris, which was the rate of 26.25% and 40.67% in normal mice and diabetic mice in respectively. The level of serum triglyceride could be reduced 23.35%. The saporin could also decrease the content of serum cholesterol. Serum SOD activity of the mice was increased by the saponin.
  
  
  CONCLUSIONS
  Saponin from Tribulue terrestris could significantly reduce the level of serum glucose.
authors.affiliation: School of Life Science, East China Normal University, Shanghai 200062.
authors.forename: Mingjuan
authors.initials: M
authors.lastname: Li
authors.forename: Weijing
authors.initials: W
authors.lastname: Qu
authors.forename: Yifei
authors.initials: Y
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Wan
authors.forename: Cuiping
authors.initials: C
authors.lastname: Tian
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D032444:Tribulus / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D012503:Saponins