[Observation on specific IgG4 antibody of schistosomiasis patients before and after treatment].
OBJECTIVE
To observe the alteration of specific IgG4 antibody of schistosomiasis patients before and after treatment.


METHODS
ELISA.


RESULTS
The SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases were 96.3% and 100%, respectively, their average OD values were 1.62 and 0.72. 6 months post treatment 18 cases were followed up, the positive rates were 94.4% and 100%, respectively, their average OD values were 1.06 and 0.56, respectively. 12 months post treatment all cases were followed up, the positive rates of SEA-IgG4 and AWA-IgG4 were 96.3% and 92.6%, respectively, their average OD values were 0.99 and 0.58, respectively.


CONCLUSIONS
No obvious changes were found in the SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases before and after treatment, whereas the antibody level of specific IgG4 was decreased.
Feng
Z
Z
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai 200025.
Qiu
L S
LS
Zhang
Y H
YH
Li
H
H
D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000909:Antibodies, Helminth / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000188:drug therapy / Q000276:immunology*
D000871:Anthelmintics; D000909:Antibodies, Helminth; D007074:Immunoglobulin G; D011223:Praziquantel