[The paradox of hemostasis in the centenarian].
Vascular aging in humans is associated with heightened coagulation enzyme activity. This state of hypercoagulability is compatible with longevity and health. Mechanisms beyond this equilibrium associated with longevity are unknown and studies on polymorphims associated with vascular disease have not been helpful in understanding this phenomenon.
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Service de Médecine Interne et Maladies Vasculaires, Hôpital Saint-Eloi, 2, avenue Bertin Sans, 34295 Montpellier.
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Janbon
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D000222:Adaptation, Physiological; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood / Q000502:physiology*; D001161:Arteriosclerosis / Q000453:epidemiology; D001779:Blood Coagulation Factors / Q000032:analysis; D001808:Blood Vessels / Q000473:pathology; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007558:Italy / Q000453:epidemiology; D012016:Reference Values; D019851:Thrombophilia / Q000453:epidemiology
D001779:Blood Coagulation Factors