title: Adjuvant effects of sugar cane extracts (SCE) in chickens.
abstract: The effects of sugar cane extracts (SCE) on immune responses in chickens were studied. Two- or 10-month-old chickens orally administered SCE (500 mg/kg/day), for 3 consecutive days before immunized with sheep red blood cells, Brucella abortus and Salmonella Enteritidis organisms, showed significantly increased and prolonged antibody responses to these antigens, compared to control chickens without SCE. Furthermore, chickens orally administered SCE also revealed enhanced delayed type hypersensitivity responses to human gamma globulin. These results indicated that SCE has immunostimulating and adjuvant effects in chickens.
authors.affiliation: Department of Molecular Immunology, Graduate School of Agricultural and Life Science, The University of Tokyo, Japan.
authors.forename: Moshira
authors.initials: M
authors.lastname: El-Abasy
authors.forename: Maki
authors.initials: M
authors.lastname: Motobu
authors.forename: Toshiya
authors.initials: T
authors.lastname: Sameshima
authors.forename: Kenji
authors.initials: K
authors.lastname: Koge
authors.forename: Takashi
authors.initials: T
authors.lastname: Onodera
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Hirota
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000375:Aging; D000818:Animals; D000906:Antibodies / Q000276:immunology; D000907:Antibodies, Bacterial / Q000276:immunology; D002003:Brucella abortus / Q000276:immunology*; D002645:Chickens / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000276:immunology*; D006109:Poaceae / Q000276:immunology*; D012477:Salmonella enteritidis / Q000276:immunology*; D012756:Sheep
chemical_list: D000276:Adjuvants, Immunologic; D000906:Antibodies; D000907:Antibodies, Bacterial; D010936:Plant Extracts