Primary dural low grade BCL-2 negative follicular lymphoma: a case report.
We report a case of low-grade follicular lymphoma presenting as a primary lesion in the intracranial dura. Based on the preoperative MRI, our patient was presumed to have meningioma. A surgical excision was performed and the histology showed features of a grade 1 follicular lymphoma predominately small-cleaved cell type. Postoperative investigations confirmed that it was the only site of involvement. The patient then received cranial radiotherapy and she is doing well with a follow up period of 18 months. To the best of our knowledge, it is the first case of a primary dural grade 1 follicular lymphoma, small-cleaved cell type.
Beriwal
Sushil
S
Department of Radiation Oncology, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
Hou
J Steve
JS
Miyamoto
Curtis
C
Garcia-Young
Jorge A
JA
D000368:Aged; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D004388:Dura Mater / Q000473:pathology; D016326:Extracellular Matrix Proteins; D005260:Female; D006801:Humans; D008224:Lymphoma, Follicular / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D015260:Neprilysin / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism
C490607:ECM1 protein, human; D016326:Extracellular Matrix Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D015260:Neprilysin