title: Sight and comfort: complex procedures in end-stage Stevens-Johnson syndrome.
abstract: BACKGROUND
  We describe our complex surgical techniques in the management of a patient with end-stage ocular surface disease from Stevens-Johnson syndrome.
  
  
  RESULTS
  Her severe discomfort due to absolute ocular dryness in the right eye was successfully treated with submandibular gland autotransplantation. Impending loss of the left eye due to repeated perforation and infection was prevented with a penetrating corneal graft covered by a new modification of a Cutler-Beard-type full-thickness lower lid skin advancement-flap. Visual rehabilitation was achieved by means of osteo-odonto-keratoprosthesis.
  
  
  CONCLUSIONS
  The procedures described allow the preservation of eyes doomed for enucleation, relief from severe discomfort and rehabilitation from corneal blindness. Due to their complex nature they require the collaborative subspecialist surgical skills of opthalmologists and maxillofacial surgeons.
authors.affiliation: Moorfields Eye Hospital, London, UK. ggeerling@ophtha.mu-luebeck.de
authors.forename: G
authors.initials: G
authors.lastname: Geerling
authors.forename: C S C
authors.initials: CS
authors.lastname: Liu
authors.forename: J K G
authors.initials: JK
authors.lastname: Dart
authors.forename: P
authors.initials: P
authors.lastname: Sieg
authors.forename: J
authors.initials: J
authors.lastname: Herold
authors.forename: J R O
authors.initials: JR
authors.lastname: Collin
mesh_terms: D000328:Adult; D001766:Blindness / Q000601:surgery*; D003316:Corneal Diseases / Q000601:surgery*; D015352:Dry Eye Syndromes / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D013262:Stevens-Johnson Syndrome / Q000601:surgery*; D013524:Surgical Flaps