title: [Single channel and whole cell recordings using patch clamp technique].
abstract: Action of ion channel on membrane is the key events of messenger transduction for excitable cells, which can be detected by the patch clamp technique. The developments of patch clamp technique have brought a revolution of life science research. The theory, work modes, single channel and whole cell recording techniques in single cells are described here in detail.
authors.affiliation: Huazhong University of Science and Technology, Institute of Biophysics and Biochemistry.
authors.forename: X L
authors.initials: XL
authors.lastname: Lou
authors.forename: Z
authors.initials: Z
authors.lastname: Zhou
authors.forename: H G
authors.initials: HG
authors.lastname: Kang
mesh_terms: D002478:Cells, Cultured; D007473:Ion Channels / Q000502:physiology; D008564:Membrane Potentials; D018408:Patch-Clamp Techniques / Q000295:instrumentation / Q000379:methods
chemical_list: D007473:Ion Channels