Managing failure to antiretroviral drugs in HIV-1-infected patients.
Managing failure to antiretroviral therapies implies the addressing of several issues: the clinical stage, the virological and the immunological response to the failing regimen, together with drug history, resistance and exposure. Each of these issues will be discussed with the aim of providing useful data to design an optimal rescue antiretroviral therapy.
Gianotti
N
N
Clinic of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy. gianotti.nicola@hsr.it
Lazzarin
A
A
D000818:Animals; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D019468:Disease Management; D024882:Drug Resistance, Viral / Q000235:genetics / Q000276:immunology; D015658:HIV Infections / Q000188:drug therapy* / Q000235:genetics / Q000276:immunology; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics / Q000276:immunology; D006801:Humans