The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS).
The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS) is in progress. The study design, accrual to date, and related research projects are described. Revised accrual rates and expected recruitment are given. 15 cancers have been detected to date, from a total of 1236 screening measurements. This event rate and the tumour grades reported are compared with recent reports from other studies in women at high risk of breast cancer.
Leach
M O
MO
Section of Magnetic Resonance, The Institute of Cancer Research and The Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK. martin@icr.ac.uk
Eeles
R A
RA
Turnbull
L W
LW
Dixon
A K
AK
Brown
J
J
Hoff
R J C
RJ
Coulthard
A
A
Dixon
J M
JM
Easton
D F
DF
Evans
D G R
DG
Gilbert
F J
FJ
Hawnaur
J
J
Hayes
C
C
Kessar
P
P
Lakhani
S
S
Liney
G
G
Moss
S M
SM
Padhani
A P
AP
Pointon
L J
LJ
Sydenham
M
M
Walker
L G
LG
Warren
R M L
RM
Haites
N E
NE
Morrison
P
P
Cole
T
T
Rayter
Z
Z
Donaldson
A
A
Shere
M
M
Rankin
J
J
Goudie
D
D
Steel
C M
CM
Davidson
R
R
Chu
C
C
Ellis
I
I
Mackay
J
J
Hodgson
S V
SV
Homfray
T
T
Douglas
F
F
Quarrell
O W
OW
Eccles
D M
DM
Gilbert
F G
FG
Crothers
G
G
Walker
C P
CP
Jones
A
A
Slack
N
N
Britton
P
P
Sheppard
D G
DG
Walsh
J
J
Whitehouse
G
G
Teh
W
W
Rankin
S
S
Boggis
C
C
Potterton
J
J
McLean
L
L
Gordon
P A L
PA
Rubin
C
C
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics; D015331:Cohort Studies; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D020022:Genetic Predisposition to Disease; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography; D008403:Mass Screening; D008875:Middle Aged; D009154:Mutation; D018579:Patient Selection; D011786:Quality Control; D012680:Sensitivity and Specificity