title: Methicillin-resistant Staphylococcus aureus in the diabetic foot clinic: a worsening problem.
abstract: OBJECTIVE
  To determine if there has been a change in the prevalence of pathogenic organisms in foot ulcers in diabetic patients in 2001 compared with our previous study in 1998.
  
  
  METHODS
  A retrospective analysis of wound swabs taken from infected foot ulcers in diabetic patients attending the outpatient clinic in the Manchester Foot Hospital over a twelve-month period. A total of 63 patients with positive wound swabs were identified.
  
  
  RESULTS
  Gram-positive aerobic bacteria still predominate (84.2%) and the commonest single isolate remains Staphylococcus aureus (79.0%) which is higher than we previously reported. MRSA was isolated in 30.2% of the patients which is almost double the proportion of MRSA-affected patients three years ago. This did not appear to be related to prior antibiotic usage. There was no increase in hospitalisation because of MRSA infection.
  
  
  CONCLUSIONS
  The problem of MRSA continues to increase despite the precautions taken to prevent MRSA spread. There is a need for a multi-centre study looking into the prevalence of MRSA in diabetic foot ulcer and how this can be reduced in the diabetic foot clinic.
authors.affiliation: Department of Medicine, Manchester Royal Infirmary, Manchester, UK. cdang@dc.cmht.nwest.nhs.uk
authors.forename: C N
authors.initials: CN
authors.lastname: Dang
authors.forename: Y D M
authors.initials: YD
authors.lastname: Prasad
authors.forename: A J M
authors.initials: AJ
authors.lastname: Boulton
authors.forename: E B
authors.initials: EB
authors.lastname: Jude
mesh_terms: D017719:Diabetic Foot / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016106:Methicillin Resistance; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy*; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology