[Effect of Chinese drugs mixture on immune function of patients with extremely severe burn].
OBJECTIVE
To study the regulatory effect of Qinghuo Baidu Yin (QHBDY, a mixture prepared with Chinese drugs) on immune function of patients with extremely severe burn (ESB).


METHODS
Thirty patients with ESB were divided into two groups, conventional therapy was given to both groups, but QHBDY was given to the treated group additionally. Immunological indices, including peripheral blood T-lymphocyte subsets, immunoglobin (IgG, IgA and IgM) and complement (C3 and C4) were determined 3 weeks after treatment to evaluate and compare the therapeutical effect in the two groups.


RESULTS
Compared with the control group, CD3, CD4, CD4/CD8, immunoglobin (IgG, IgA and IgM) and complement (C3 and C4) levels were markedly decreased in degree, and recovered earlier and quicker, with CD8 increased mildly (P < 0.01) and turned back more quickly. And so did the parameters of the treated group in comparing with that of the control group at anytime (P < 0.05 or P < 0.01).


CONCLUSIONS
Chinese drugs mixture shows the regulatory effect on both cellular and humoral immune function in patients with ESB.
Luo
Cheng-qun
CQ
Department of Burns and Plastic Surgery, Third Xiang-ya Hospital, Central Southern University, Changsha 410013.
Zhou
Jian-da
JD
He
Quan-yong
QY
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D002056:Burns / Q000188:drug therapy* / Q000276:immunology; D003176:Complement C3; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
D000276:Adjuvants, Immunologic; D003176:Complement C3; D004365:Drugs, Chinese Herbal; D007074:Immunoglobulin G