[Effect of fuzheng jianpi recipe on content of trace element and immune function in children with spleen deficiency anorexia].
OBJECTIVE
To evaluate the efficacy and prospect of Fuzheng Jianpi Recipe (FZJPR) in treating children's Spleen deficiency anorexia (CSDA) by means of observing its effect on trace element content and immune function.


METHODS
One hundred and thirty cases of CSDA were treated with FZJPR, one dose per day in decoction, orally taken, 30 days for one therapeutic course. Levels of T-lymphocyte subsets, IL-2R, immunoglobulin and trace elements were determined before and after treatment, and compared with those in the control group consisted of 60 healthy children.


RESULTS
In the treated group, abnormal figures were shown in T-lymphocyte subsets, especially in lowering of CD3 and CD4 count before treatment, and IgG content was reduced also. After treatment, CD3, CD4, CD4/CD8 ratio as well as IgG and IgA were improved significantly (P < 0.01), IL-2R percentage approached normal. Moreover, the levels of Zn and Fe changed significantly (P < 0.01).


CONCLUSIONS
FZJPR could improve the trace elements content and immune function in CSDA children, so it is effective in treating CSDA.
Tao
La-di
LD
Children Hospital of Shanxi Province, Taiyuan 030013.
Qin
Shao-ai
SA
D000855:Anorexia / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008517:Phytotherapy; D015375:Receptors, Interleukin-2 / Q000097:blood; D016176:T-Lymphocyte Subsets / Q000187:drug effects*; D014131:Trace Elements / Q000097:blood*; D016711:Yang Deficiency / Q000097:blood / Q000188:drug therapy / Q000276:immunology
D004365:Drugs, Chinese Herbal; D007074:Immunoglobulin G; D015375:Receptors, Interleukin-2; D014131:Trace Elements