title: Emerging cancer-targeted therapies.
abstract: There is reason to believe that the unfolding revolution in molecular biology and translational research will allow selective targeting of tumor cells, and radically change the way general practitioners and pediatric oncologists treat and follow children with cancer. This article highlights some of the most promising approaches being tested in the field. By learning about the underlying biology, the remaining hurdles, the projected timeline, and the possible impact of new therapies on the practice of pediatric oncology, health care professionals and patients should be better prepared for the future of pediatric oncology.
authors.affiliation: Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, Room 2M51, Baltimore, Maryland 21231, USA. arcecro@jhmi.edu
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Arceci
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Cripe
mesh_terms: D019496:Cancer Vaccines; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008967:Molecular Biology / Q000379:methods*; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D014765:Viral Vaccines / Q000627:therapeutic use*
chemical_list: D019496:Cancer Vaccines; D014765:Viral Vaccines