Azithromycin reduces the production of virulence factors in Pseudomonas aeruginosa by inhibiting quorum sensing.
Pechère
J C
JC
Department of Genetics and Microbiology, University of Geneva.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017963:Azithromycin / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D002450:Cell Communication / Q000187:drug effects* / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics; D003864:Depression, Chemical; D006017:Glycolipids / Q000096:biosynthesis; D008025:Ligases; D010196:Pancreatic Elastase / Q000096:biosynthesis; D011550:Pseudomonas aeruginosa / Q000378:metabolism* / Q000472:pathogenicity / Q000502:physiology; D015534:Trans-Activators / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics; D014158:Transcription, Genetic / Q000187:drug effects; D037521:Virulence Factors / Q000096:biosynthesis*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D006017:Glycolipids; C081237:LasI protein, Pseudomonas aeruginosa; C080365:LasR protein, Pseudomonas aeruginosa; C085427:LuxI protein, Bacteria; C086515:RhlR protein, Pseudomonas aeruginosa; D015534:Trans-Activators; D014157:Transcription Factors; D037521:Virulence Factors; C418382:rhamnolipid; D017963:Azithromycin; D010196:Pancreatic Elastase; D008025:Ligases; C096955:RHLI protein, Pseudomonas aeruginosa