Significant risk of a second melanoma in patients with a history of melanoma but no further predisposing factors.
It is a well-accepted fact that melanoma patients are prone to develop further melanomas. In a cohort of 535 melanoma patients, we determined the incidence of second melanomas, as well as risk factors known to be associated with melanoma development. A retrospective analysis of patients regularly consulting our melanoma care unit revealed second or even further melanomas in 5.6% (n = 30). When compared to the overall population, melanoma patients have at least a 30-fold increased risk for the development of a second melanoma. Twenty of these 30 patients revealed none of the known predisposing conditions for multiple melanomas.
Nashan
Dorothee
D
Kocer
Burak
B
Schiller
Meinhard
M
Luger
Thomas
T
Grabbe
Stephan
S
D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors