Metastatic gastroesophageal junction adenocarcinoma to the extraocular muscles.
OBJECTIVE
To present one definitive and one probable case of gastroesophageal adenocarcinoma metastases to the extraocular muscles.


METHODS
Two observational case reports.


METHODS
Two interventional case reports with clinical pathologic correlation and review of the literature. Vanderbilt University Institutional Review Board approval was obtained for this report.


METHODS
We analyzed the presenting symptoms, visual acuity, motility, and external examination.


RESULTS
Computed tomography showed nodular enlargement of an isolated rectus muscle. Histopathologic examination confirmed the diagnosis of metastatic gastrointestinal carcinoma in one case. The orbital neoplasm contained signet ring cells, classically seen in gastrointestinal malignancy.


CONCLUSIONS
Metastasis from gastrointestinal carcinoma should be considered in the differential diagnosis of a patient presenting with diplopia or visual loss, particularly with a recent history of gastrointestinal malignancy.
Lekse
Jaclyn M
JM
Vanderbilt University School of Medicine, Nashville, TN 37232-8808, USA.
Zhang
Jing
J
Mawn
Louise A
LA
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D000368:Aged; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000473:pathology*; D004943:Esophagogastric Junction / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009801:Oculomotor Muscles / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D014057:Tomography, X-Ray Computed