[A mathematical model for prediction of the effect of hyperlipidemia on thickness of the intima-media complex in the carotid artery wall as an indicator of atherosclerosis].
The growth of intima media complex is widely accepted parameter in studies that are in relation to the process of atherosclerosis. Increased value of intima-media thickness (IMT) a. carotis communis is the incontestable index of atherosclerosis process in regard to distinct vascular spheres and wider cardiovascular risk. Hypercholesterolemia as the well-known promoter of atherogenesis influence on the increase of IMT. It is established that there is a highly valuable connection (p < 0.001) between the levels of cholesterol and the thickness of IMT. It is also observed a highly significant linear and cubic correlation between the cholesterol and IMT. Concerning the relationship between trigliceride and IMT, it stands out as the highly relevant (R = 0.42; p < 0.001) but the coefficient of correlation is fewer than cholesterol (R = 0.56). Increased value of cholesterol and triglicerides exerts influence on IMT of a. carotis communis simultaneously which leads to highly consequential equation: IMT = 0.005 x TG-0.008 x Chol + 0.28. This mathematics model can be noteworthy if one anticipates effects of primary and secondary prevention.
Nedeljković
Marija
M
Health Centre, Uzhice.
Petrović
Branko
B
Djurić
Dragan
D
D001161:Arteriosclerosis / Q000209:etiology* / Q000473:pathology; D002340:Carotid Artery Diseases / Q000209:etiology* / Q000473:pathology; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D012307:Risk Factors; D017539:Tunica Intima / Q000473:pathology*; D017540:Tunica Media / Q000473:pathology*; D014463:Ultrasonography