title: [Isolation and identification of steroidal saponins from Dioscorea panthaica Prain et Burkill].
abstract: OBJECTIVE
  To investigate the chemical constituents of the rhizomes of Dioscorea panthaica Prain et Burkill and look for new active compounds.
  
  
  METHODS
  The compounds were isolated with silica gel and HPLC, and their structures were elucidated on the basis of chemical evidences and spectral analysis (IR, ESI-MS, 1HNMR, 13CNMR, DEPT, 1H-1H COSY, HMQC, HMBC, NOESY).
  
  
  RESULTS
  Three steroidal saponins were isolated from the rhizomes of Dioscorea panthaica. They were elucidated as 26-O-beta-D-glucopyranosyl-3 beta, 26-diol-23(S)-methoxy-25(R)-delta 5,20(22)-diene-furosta-3-O-[alpha-L-rhamnopyranosyl-(1-->2)- O-alpha-L-rhamnopyranosyl-(1-->4)]-beta-D-glucopyranoside (I), pseudoprotodioscin (II), 26-O-beta-D-glucopyranosyl-3 beta, 26-diol-25 (R)-delta 5,20(22)-diene-furosta-3-O-alpha-L-rhamnopyranosyl- (1-->2)-O-beta-D-glucopyranoside (III).
  
  
  CONCLUSIONS
  Compound I is a new steroidal saponin and was named as dioscoreside C. Compound II and III were obtained from this genus for the first time.
authors.affiliation: Department of Natural Medicinal Chemistry, Shenyang Pharmaceutical University, Shenyang 110015, China.
authors.forename: M
authors.initials: M
authors.lastname: Dong
authors.forename: L J
authors.initials: LJ
authors.lastname: Wu
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
authors.forename: B X
authors.initials: BX
authors.lastname: Wang
mesh_terms: D027742:Dioscorea / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012503:Saponins; D013256:Steroids; C452800:dioscoreside C