title: [Central pontine and extra-pontine myelinolysis in an alcoholic patient without hydro-electrolyte disturbances: case report].
abstract: Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) are different presentations of a demyelinating disorder of the brain more commonly associated with rapid correction of hyponatremia, spastic tetraparesia and pseudo-bulbar palsy. There are in the literature a few cases of CPM/EPM in patients without electrolyte disturbances. We report the case of a 39 year-old man with severe alcoholism, who presented with spastic tetraparesis and palsy of several cranial nerves, associated with lesions in the magnetic resonance compatible with CPM/EPM. The patient had a good follow-up after pulse therapy with corticosteroids.
authors.affiliation: Serviço de Neurologia, Departamento de Clinica Medica, Hospital de Clinicas da Universidade Federal do Parana, Curitiba, PR, Brasil.
authors.forename: Francisco Manoel B
authors.initials: FM
authors.lastname: Germiniani
authors.forename: Mauricio
authors.initials: M
authors.lastname: Roriz
authors.forename: Samir K
authors.initials: SK
authors.lastname: Nabhan
authors.forename: Helio A G
authors.initials: HA
authors.lastname: Teive
authors.forename: Lineu C
authors.initials: LC
authors.lastname: Werneck
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors; D014882:Water-Electrolyte Balance