Temporal and spatial coordination of exocytosis and endocytosis.
In secretory cells, exocytosis and compensatory endocytosis are tightly coupled membrane trafficking processes that control the surface area and composition of the plasma membrane. While exocytic and endocytic processes have been studied independently in great detail, at present there is much interest in understanding the mode of their coupling. This review discusses emerging insights into the coupling of these processes, both in the chemical synapses of neurons and in non-neuronal cells.
Gundelfinger
Eckart D
ED
Leibniz Institute for Neurobiology, Department of Neurochemistry and Molecular Biology, Brenneckestr. 6, 39118 Magdeburg, Germany. gundelfinger@ifn-magdeburg.de
Kessels
Michael M
MM
Qualmann
Britta
B
D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D009474:Neurons / Q000502:physiology; D021381:Protein Transport; D015398:Signal Transduction; D013569:Synapses
D002118:Calcium