[Climbing-upward inhibition of Oncomelania hupensis by niclosamide combination].
OBJECTIVE
To develop a combination of molluscicide/insecticide with a good molluscicidal effect, especially an inhibitory effect on climbing-upward of Oncomelania hupensis.


METHODS
Experiments on molluscicidal and snail-climbing inhibition effect of the combination of niclosamide and shachongding [(dimethylamine) trithacyclohexane hydrochloride] were conducted by immersion and spraying in laboratory.


RESULTS
The combination of niclosamide (0.2 mg/L) and shachongding (0.1 mg/L) showed an inhibition of 92.67% of snails to climb up. There was no significant difference in molluscicidal effect between the combination (LC90 0.198 mg/L) and niclosamide alone (LC90 0.207 mg/L).


CONCLUSIONS
The combination showed an effective inhibition on the climbing-upward of snails in water so as to improve the molluscicidal effect and reduce the cost of mollusciciding.
Zhu
D
D
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai 200025.
Xie
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Bao
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Zhu
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D000818:Animals; D004123:Dimethylamines / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D008975:Molluscacides / Q000494:pharmacology*; D009534:Niclosamide / Q000494:pharmacology*; D012908:Snails / Q000187:drug effects*
D004123:Dimethylamines; D008975:Molluscacides; D009534:Niclosamide; C034516:dimethylamine