[Comparison studies on pharmacodynamics of three kind of Carapax trionycis].
Three kinds of Carapax Trionycis were used in rat to prevent and treat syndrom-complex of dificiency of Yin. Compareing the improvement of symptoms of dificiency of Yin, it was found that all of them actted effectively in various degrees. The effect of ZhongHua Carapax Trionycis (ZHCT) was similar to those of Shan Rui Carapax Trionycis (SRCT), but the efficacy of Green Carapax Trionycis (GCT) was inferior to those of ZHCT and SRCT. All kinds of C. Trionycis could increase the function of responding to iriation in mice with deficiency of Yin. The intensity of ZHCT was similar to that of GCT, and superior to that of SRCT. They all could enhance phagocytic function of eticuloedothelial system obviously, promot the development of thymus in different degrees with no efect on spleen in young mice. The efficacy of increasing the immune function of ZHCT and GCT were more potent than that of SRCT. ZHCT and GCT significantly decreased the activity of SGPT in mice poisoned by CC14. ZHCT and GCT protected liver better than SRCT did.
Zhou
A
A
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700.
Tian
J
J
Guo
S
S
Fu
H
H
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy; D005260:Female; D008297:Male; D008419:Materia Medica / Q000494:pharmacology* / Q000592:standards; D051379:Mice; D011786:Quality Control; D051381:Rats; D017208:Rats, Wistar; D012104:Reptiles / Q000145:classification*; D016710:Yin Deficiency / Q000188:drug therapy
D008419:Materia Medica