[Detection of Toxoplasma infection in women with gynaecologic neoplasms using ELISA].
OBJECTIVE
To understand the concurrent in Toxoplasma infection among women with cervical cancer.


METHODS
The anti-Toxoplasma IgG, IgM antibodies (Abs) and circulating antigens (CAg) in 247 sera (from 50 cases with cervical cancer in group 1, 59 cases with gynaecological benign tumors in group 2 and 138 cases with other diseases in group 3) were detected by ELISA.


RESULTS
The total positive rates of the CAg and the Abs in the three groups were 44.0% (22/50), 25.4% (15/59) and 20.3% (28/138), respectively. The positive rates were 20.0%, 11.9% and 10.9%, respectively for IgG 20.0%, 13.6% and 8.7%, respectively for IgM and 14.0%, 5.1% and 1.4% respectively for CAg.


CONCLUSIONS
The Toxoplasma infection rate of the cervical cancer group was higher than those of the other two groups, particularly the positive rates of CAg and IgM.
Huang
H
H
Institute of Virology, Hubei Academy of Medical Sciences, Wuhan 430079.
Yan
F H
FH
Li
C J
CJ
Zhao
M Y
MY
Tang
J W
JW
Li
X R
XR
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000150:complications*
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M