Meliternatin: a feeding deterrent and larvicidal polyoxygenated flavone from Melicope subunifoliolata.
We screened more than 60 Malaysian plants against two species of insects and found that Melicope subunifoliolata (Stapf) T.G. Hartley (Rutaceae) showed strong feeding deterrent activity against Sitophilus zeamais Motsch. (Curculionidae) and very good larvicidal activity against Aedes aegypti L. (Diptera). One anti-insect compound, meliternatin (3,5-dimethoxy-3',4',6,7-bismethylendioxyflavone) (6) and six other minor polyoxygenated flavones were isolated from M. subunifoliolata.
Hung Ho
Shuit
S
Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. dbshosh@nus.edu.sg
Wang
Jing
J
Sim
K Y
KY
Ee
Gwendoline C L
GC
Imiyabir
Zamrie
Z
Yap
K F
KF
Shaari
Khozirah
K
Hock Goh
Swee
S
D000330:Aedes / Q000254:growth & development; D000818:Animals; D001517:Coleoptera / Q000254:growth & development; D004435:Eating / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D007928:Lethal Dose 50; D019906:Nuclear Magnetic Resonance, Biomolecular; D027821:Rutaceae / Q000737:chemistry*
D005419:Flavonoids; D007306:Insecticides; C474048:meliternatin