[Lysosomal enzymes of the liver and kidney in unspecific purulent kidney disease].
Unspecific inflammatory lesions of the urinary tract are known to be a vital question in urology and nephrology of our country and in foreign ones. Used in experiments were rats of mixed population. Lysosomal enzymes were studied in homogenates of the liver and contralateral kidney tissues and in the blood serum as well 1, 3, 6 days after simulation of the pathology experimental model. Activities were measured of such lysosomal enzymes as acid DNA-ase and RNA-ase, cathepsin, and acid phosphatase. Results of the studies made showed that in unspecific purulent affection of the kidneys there occurs an activation of acid blood hydrolases followed by their activation in the liver. The contralateral kidney, because of it being linked in functioning with the liver, remains relatively "inert" with respect to activation of lysosomal enzymes.
Mavlianov
I R
IR
Mukhitdinov
B B
BB
Akhmadaliev
N N
NN
D000135:Acid Phosphatase / Q000097:blood / Q000378:metabolism; D000818:Animals; D002402:Cathepsin D / Q000097:blood / Q000378:metabolism; D003851:Deoxyribonucleases / Q000097:blood / Q000378:metabolism; D004195:Disease Models, Animal; D005260:Female; D007668:Kidney / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009393:Nephritis / Q000097:blood / Q000201:enzymology*; D051381:Rats; D012260:Ribonucleases / Q000097:blood / Q000378:metabolism; D013492:Suppuration; D013997:Time Factors
D003851:Deoxyribonucleases; D012260:Ribonucleases; D000135:Acid Phosphatase; D002402:Cathepsin D