title: Differential gene expression in retina of myopic chicken eyes using mRNA differential display.
abstract: OBJECTIVE
  To study differentially expressed genes in retina of experimental myopic chicken.
  
  
  METHODS
  Experimental myopia in chicken was induced by form-deprivation. The mRNA in chicken retina was analyzed by using differential display.
  
  
  RESULTS
  Experimental myopia was successfully induced in chicken through form-deprivation. Differentially expressed gene fragments were detected in retina of chicken with myopic development and recovery as compared with normal controls.
  
  
  CONCLUSIONS
  The differential display of mRNA may be a useful way in cloning myopic-related genes.
authors.affiliation: Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
authors.forename: H
authors.initials: H
authors.lastname: Shen
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.forename: X
authors.initials: X
authors.lastname: Xiao
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: X
authors.initials: X
authors.lastname: Guo
authors.forename: X
authors.initials: X
authors.lastname: Jia
authors.forename: L
authors.initials: L
authors.lastname: Guo
mesh_terms: D000818:Animals; D002645:Chickens; D018076:DNA, Complementary; D020869:Gene Expression Profiling / Q000379:methods; D009216:Myopia / Q000235:genetics*; D016133:Polymerase Chain Reaction / Q000379:methods; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics*; D012160:Retina / Q000378:metabolism*
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger