[Effect of airborne fungi on interleukin-4 mRNA expression in the peripheral blood mononuclear cells of rats].
The effect of indoor airborne fungi on interleukin-4 (IL-4) mRNA expression in the peripheral blood mononuclear cells (PBMCs) of rats was studied by inoculating via trachea with fungi suspension. A simplified competitive RT-PCR method was used to measure the IL-4 mRNA expression in plasma. The results showed that interleukin-4 expression was much higher in the affected groups than that in the control one. It suggested that IL-4 might play an important role in the sensitization progress of fungi.
Kan
H
H
Public Health School, Fudan University, Shanghai 200032, China.
Song
W
W
Jiang
R
R
D000391:Air Microbiology; D000818:Animals; D005260:Female; D015847:Interleukin-4 / Q000096:biosynthesis* / Q000235:genetics; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D008297:Male; D009181:Mycoses / Q000097:blood*; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D012333:RNA, Messenger; D015847:Interleukin-4