The effect of latanoprost on accommodation in young patients with ocular hypertension.
OBJECTIVE
To determine whether topical latanoprost 0.005% had an effect on accommodative capacity after 1 month of treatment in young patients with ocular hypertension.


METHODS
Fifteen patients (9 men and 6 women, aged 20-40 years) with ocular hypertension were instructed to instill the drug to their right eye for 1 month; the left eye received no medication and served as control. Near point of accommodation, refraction, and intraocular pressure (IOP) were determined after 1 month of treatment.


RESULTS
After 1 month of treatment with latanoprost, the mean IOP was reduced by 22.8% (5.8 mm Hg) in the treated eye and 1.86% (0.47 mm Hg) in the untreated control eye. No significant changes in refraction or near point of accommodation were observed in the treated or untreated eye.


CONCLUSIONS
Short-term treatment with latanoprost 0.005% does not effect refraction or accommodation in young patients with ocular hypertension.
Kurtz
Shimon
S
Department of Ophthalmology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Leibovitch
Igal
I
Shemesh
Gabi
G
Rothkoff
Levi
L
Loewenstein
Anat
A
D000065:Accommodation, Ocular / Q000187:drug effects*; D000328:Adult; D000959:Antihypertensive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D000077338:Latanoprost; D008297:Male; D009798:Ocular Hypertension / Q000188:drug therapy*; D011461:Prostaglandins F, Synthetic / Q000494:pharmacology* / Q000627:therapeutic use; D012029:Refraction, Ocular / Q000187:drug effects
D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost