title: Chlorine inactivation of spores of Encephalitozoon spp.
abstract: This report is an extension of a preliminary investigation on the use of chlorine to inactivate spores of Encephalitozoon intestinalis and to investigate the effect of chlorine on two other species, E cuniculi and E. hellem, associated with human infection. The 50% tissue culture infective doses of these three species were also determined. On the basis of the results obtained, it appears that chlorination of water is an effective means of controlling spores of these organisms in the aquatic environment.
authors.affiliation: U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA. johnson.cliff@epa.gov
authors.forename: C H
authors.initials: CH
authors.lastname: Johnson
authors.forename: M M
authors.initials: MM
authors.lastname: Marshall
authors.forename: L A
authors.initials: LA
authors.lastname: DeMaria
authors.forename: J M
authors.initials: JM
authors.lastname: Moffet
authors.forename: D G
authors.initials: DG
authors.lastname: Korich
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002713:Chlorine / Q000494:pharmacology*; D015169:Colony Count, Microbial; D004203:Disinfection / Q000379:methods*; D016819:Encephalitozoon / Q000145:classification / Q000187:drug effects / Q000472:pathogenicity* / Q000502:physiology*; D009670:Encephalitozoon cuniculi / Q000187:drug effects / Q000472:pathogenicity / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000166:cytology; D010274:Parasitology / Q000379:methods; D011817:Rabbits; D033761:Spores, Protozoan / Q000187:drug effects / Q000502:physiology
chemical_list: D002713:Chlorine