[Effect of songling xuemaikang capsule combined with captopril on quality of life in primary hypertension patients].
OBJECTIVE
To compare the hypotensive effects of captopril and combined medication of Songling Xue-maikang Capsule (SXC) with captopril on quality of life (QOL) in treating primary hypertension patients.


METHODS
For 166 hypertension patients, a perspective randomized double blind study was performed with both sexes, aged 42-78 years, blood pressure (BP) ranged > or = 140/90 mmHg and < or = 200/110 mmHg. Patients were randomly divided into two groups: captopril group and combined medication group. Each patient should answer the QOL questionnaire independently before and after experiment. 60 age-matched normotensive subjects without chronic diseases served as control.


RESULTS
Both hypertension groups showed an improvement of BP and QOL after treatment, but the combined medication group had a higher score in sense of well being, physical symptom-signs, work performance and life satisfaction than the captopril group had.


CONCLUSIONS
Combined medication of captopril and SXC had better effect than captopril alone either in lowering BP or in improving QOL of primary hypertension patients.
Chen
W Q
WQ
Foshan Municipal TCM Hospital, Guangdong 528000.
Chen
F R
FR
D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002216:Captopril / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011788:Quality of Life
D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; C000606146:songling xuemaikang; D002216:Captopril