title: Clinical characteristics of under-reporters on urine drug screens in a cocaine treatment study.
abstract: To explore the concordance between urine drug screen (UDS) results and self-report of cocaine use, results in a pharmacologic treatment trial for cocaine dependence were evaluated. Subjects with at least two occurrences of a positive UDS for cocaine were characterized as either an under-reporter (UR, n = 43) or a truthful reporter (TR, n = 32). Interestingly, URs attended more study sessions and were more likely to complete the study. Significant differences were found in cocaine use patterns and the prevalence of Axis I and Axis II disorders. This information may be important in guiding the judicious use of UDS in clinical and research settings.
authors.affiliation: Medical University of South Carolina, Department of Psychiatry, Center for Drug and Alcohol Programs, 67 President Street, Charleston, SC 29425, USA. myrickh@musc.edu
authors.forename: Hugh
authors.initials: H
authors.lastname: Myrick
authors.forename: Scott
authors.initials: S
authors.lastname: Henderson
authors.forename: Bonnie
authors.initials: B
authors.lastname: Dansky
authors.forename: Christine
authors.initials: C
authors.lastname: Pelic
authors.forename: Kathleen T
authors.initials: KT
authors.lastname: Brady
mesh_terms: D000328:Adult; D019970:Cocaine-Related Disorders / Q000188:drug therapy / Q000523:psychology* / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology*; D012650:Self Disclosure; D015813:Substance Abuse Detection