[Analysis of TTV infection in patients of hemodialysis and bone marrow transplantation].
OBJECTIVE
To make clear the infection of TT virus(TTV) in patients of hemodialysis and bone marrow-transplantation and to evaluate the virulence.


METHODS
The TTV infection were investigated in 37 cases of hemodialysis and 90 cases of bone marrow-transplantation by means of review method.


RESULTS
The positive rate of TTV was 16.22% (6/37) in 37 cases of hemodialysis and 3.33% (3/90) in 90 cases of bone marrow-transplantation. The difference between them was significant(P < 0.01). Of the six TTV-positive patients, 5 had blood transfusion and 4 of them had bone marrow-transplantation. Infection of TTV had nothing to do with the infection of HBV and HCV. There were no significant differences in the results of liver function tests between TTV positive and TTV negative patients.


CONCLUSIONS
These results suggest that blood transfusion might be one of the critical routes to transmit TTV. The virulence of TTV might be mild. Whether TTV is a hepatitis viral remains further study.
Lin
C
C
Third Affiliated Hospital, SUN Yat-sen University of Medical Sciences, Guangzhou 510630.
Huang
Y
Y
Chen
W
W
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002681:China / Q000453:epidemiology; D004266:DNA Virus Infections / Q000453:epidemiology / Q000635:transmission*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D012189:Retrospective Studies; D022783:Torque teno virus