title: Comparative diagnostic test characteristics of oscillometric and Doppler ultrasonographic methods in the detection of systolic hypertension in dogs.
abstract: Comparison of test characteristics allows a clinician to choose the optimal diagnostic test method for an individual patient. This study assessed the comparative test characteristics of noninvasive (NI) blood pressure measurement methods (oscillometric and Doppler) and used this information to develop optimal cutoff values for diagnosis of systolic hypertension in dogs by these NI methods. Simultaneous NI (oscillometric or Doppler methods) and invasive (arterial puncture [AP]) systolic blood pressure (SBP) measurements were obtained prospectively from normal dogs and dogs suspected of having systemic hypertension based on clinical signs. Oscillometric SBP readings were obtained from the distal hind limb (Osc-L, n = 54) or the proximal tail (T. n = 27). Doppler BP measurements were obtained using a forelimb cuff (n = 57). AP-SBP was categorized as hypertensive if > or = 160 mmHg, and sensitivity (Se). specificity (Sp), and likelihood ratios (LR) were calculated for diagnostic cutoff values ranging from 130 to 220 mmHg. Receiver operator characteristic (ROC) curves were analyzed to determine optimal cutoff values for diagnosis of AP-SBP > or = 160 mmHg. Optimal NI SBP cutoff values considered to reflect AP values > or = 160 mmHg were: Osc-L = 160 mmHg (Se: 65%, Sp: 85%. LR = 4.33: 1), Osc-T = 150 mmHg (Se: 84%, Sp: 75%, LR = 3.36: 1), and Doppler = 160 mmHg (Se: 71%,
authors.affiliation: Department of Medical Sciences, University of Wisconsin School of Veterinary Medicine, Madison, WI 53706-1102, USA. stepienr@svm.vetmed.wisc.edu
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Stepien
authors.forename: Gregg S
authors.initials: GS
authors.lastname: Rapoport
authors.forename: Rosemary A
authors.initials: RA
authors.lastname: Henik
authors.forename: Lisa
authors.initials: L
authors.lastname: Wenholz
authors.forename: Chester B
authors.initials: CB
authors.lastname: Thomas
mesh_terms: D000818:Animals; D001795:Blood Pressure Determination / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D005260:Female; D006973:Hypertension / Q000175:diagnosis* / Q000662:veterinary*; D008297:Male; D009991:Oscillometry / Q000662:veterinary*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler / Q000662:veterinary*