title: Superior vena cava syndrome due to fibrosing mediastinitis histologically identical to xanthogranulomatous pyelonephritis.
abstract: We present herein a case of superior vena cava (SVC) syndrome caused by localized fibrosing mediastinitis (FM), which had histological features similar to xanthogranulomatous pyelonephritis (XGP). A 63-year-old woman presented with facial swelling 5 months after undergoing right nephrectomy for XGP. Radiologic investigations of the chest confirmed the presence of SVC obstruction due to an intraluminal tumor. The histological features of the tumor were consistent with those of FM and were very similar to those of XGP. Although the pathogenesis of neither FM nor XGP is known, some pathogenic process of FM and XGP may be the same.
authors.affiliation: Department of Cardiology, Juntendo University Izunagaoka Hospital, 1129 Nagaoka, Izunagaoka-cho, Tagata-gun, Shizuoka 410-2295.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kojima
authors.forename: Masataka
authors.initials: M
authors.lastname: Sumiyoshi
authors.forename: Satoru
authors.initials: S
authors.lastname: Suwa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tamura
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Sasaki
authors.forename: Takahiko
authors.initials: T
authors.lastname: Kojima
authors.forename: Yoriaki
authors.initials: Y
authors.lastname: Mineda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohta
authors.forename: Michio
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Yasuro
authors.initials: Y
authors.lastname: Nakata
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D008480:Mediastinitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009392:Nephrectomy; D011705:Pyelonephritis, Xanthogranulomatous / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D013479:Superior Vena Cava Syndrome / Q000209:etiology*