[Evolution of inflammatory parameters after fibroid embolization].
OBJECTIVE
To describe the rise of classical laboratory tests for inflammation following transarterial uterine fibroid embolization (UFE) in order to monitor the normal course following UFE.


METHODS
In 20 females, white blood cell (WBC) count and C-reactive protein (CRP) were determined before and up to 5 days after UFE. With the exception of one noninflammatory complication, the post-procedure course was uneventful in all patients. The measured values were correlated with both the total uterine volume and the amount of instilled embolizing agent.


RESULTS
Following UFE, an increase in the WBC count to an average maximum of 10.8 +/- 3.5/wL (range 5.9 - 18.6/wL) was found. In 13 of 20 patients, the WBC count was above normal on at least one day following UFE. The increase reached the maximum on the third post-interventional day and subsided within 5 days after the UFE. The CRP values increased significantly to an average maximum of 41.9 +/- 28.8 mg/l. The maximum was found on the 2nd post-interventional day in 8 patients, on the 3rd day in 11 patients and on the 4th day in one patient. No correlation to the total uterine volume or to the amount of the instilled embolizing agents was detected.


CONCLUSIONS
Following uncomplicated UFE, a steep increase in CRP occurs with no or only a mild increase in the WBC count, which does not indicate an infected fibroid. The maximum is reached on the 3rd or 4th post-interventional day, followed by a decline in CRP and normalization of the WBC count.
Vorwerk
D
D
Institut für Diagnostische und Interventionelle Radiologie, Klinikum Ingolstadt. dierk.vorwerk@klinikum.ingoldstadt.de
Rosen
T
T
Keller
E
E
Gruber
N
N
Lenz
G
G
D000328:Adult; D000792:Angiography; D002097:C-Reactive Protein / Q000378:metabolism*; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply / Q000276:immunology / Q000628:therapy*; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000098:blood supply / Q000276:immunology / Q000628:therapy*
D002097:C-Reactive Protein