[Effect of electro-acupuncture on calcium content in neurocytes of focal cerebral ischemia].
OBJECTIVE
To study the effect of electro-acupuncture (EA) in regulating calcium (Ca2+) content in brain neurocytes of rats with focal cerebral ischemia.


METHODS
The changes of Ca2+ content in ischemic neurocytes were observed by using laser confocal scanning microscope.


RESULTS
Ca2+ content did not change significantly in cerebral cortex when the brain ischemia occurred for 1 hr, but it raised significantly in striatum neurocytes. Both the Ca2+ contents in striatum and cortex area increased significantly 3 hrs after ischemia occurrence and the content in striatum was higher than that in cortex significantly. Brain Ca2+ content could be reduced significantly after the 3 hrs ischemic brain were treated by EA for 30 min.


CONCLUSIONS
EA could regulate the content of Ca2+ in the ischemic area of brain, inhibit Ca2+ overload, so as to protect neurons from ischemic injury.
Xu
Neng-gui
NG
College of Acupuncture and Massage, Guangzhou TCM University, Guangzhou 510405.
Yi
Wei
W
Lai
Xin-sheng
XS
D000818:Animals; D001693:Biological Transport, Active; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D002118:Calcium / Q000378:metabolism*; D015671:Electroacupuncture; D020244:Infarction, Middle Cerebral Artery / Q000378:metabolism* / Q000473:pathology; D008297:Male; D018613:Microscopy, Confocal; D009474:Neurons / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D002118:Calcium