[Effect of drinking mineral water on hormonal regulation of glucose homeostasis after mastectomy for breast cancer].
Glycohomeostasis was studied in patients operated for breast cancer, healthy controls and ulcer patients before and after gastric resection (each group consisted of 12-15 examinees). Patients with duodenal ulcer had insulin hypersection including early phase reaction. Gastric resection decreases insulinemia in an early phase of reaction to oral glucose test. In postmastectomy patients insulinemia is 2-3 times higher than that in duodenal ulcer patients and 5 times higher than that in healthy subjects. Besides hyperinsulinemia, they had insulin resistance and impaired carbohydrate tolerance. A course intake of mineral water raised tissue sensitivity to insulin at early stages of glucose test and lowered basal level of insulin and hydrocortisone.
Polushina
N D
ND
Vladimirov
V I
VI
Frolkov
V K
VK
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D001943:Breast Neoplasms / Q000378:metabolism / Q000601:surgery*; D005260:Female; D005951:Glucose Tolerance Test; D006706:Homeostasis / Q000187:drug effects*; D006728:Hormones / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000097:blood; D008408:Mastectomy; D008875:Middle Aged; D008900:Mineral Waters / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000097:blood / Q000534:rehabilitation*
D001786:Blood Glucose; D006728:Hormones; D007328:Insulin; D008900:Mineral Waters