title: [Study on the posterior vitreous detachment in patients with high myopia].
abstract: OBJECTIVE
  To access the development of posterior vitreous detachment(PVD) related to age, axial length of the eye, vitreous changes as well as the myopic chorioretinal manifestation in patients with high myopia.
  
  
  METHODS
  The vitreous status of 61 consecutive patients with high myopia(> or = -8.0 D and axial length > or = 26.0 mm) 110 eyes and 68 controls (< or = -3.0 D) 119 eyes were examined with biomicroscopic slit lamp and B-scan ultrasound. The myopic chorioretinal changes at the posterior pole were examined by indirect ophthalmoscope. The axial length of the eye was measured by A-scan ultrasound. The incidence of PVD was evaluated by Chi-square test.
  
  
  RESULTS
  The incidence of PVD in patients with high myopia increased with age. Its overall incidence was significantly higher than that in the controls (78.2% vs 31.1%, P < 0.001). In addition, the onset of PVD in patients with high myopia occurred much earlier in age than that in the control group. Axial length was an important factor responsible for the development of PVD in patients with high myopia. The incidence of PVD and age were highly correlated (r = 0.9997, P < 0.05). Retinal detachment occurred in 5 eyes in the patients with high myopia.
  
  
  CONCLUSIONS
  The results in the present study suggested that the incidence of PVD in patients with high myopia, increased with axial length of the eye and age. Vitreous changes are characteristic findings associated with high myopia, which was also involved in the development of PVD.
authors.affiliation: Department of Ophthalmology, PUMC Hospital, CAMS and PUMC, Beijing 100730.
authors.forename: J
authors.initials: J
authors.lastname: Ye
authors.forename: C
authors.initials: C
authors.lastname: Zhou
authors.forename: H
authors.initials: H
authors.lastname: Du
authors.forename: R
authors.initials: R
authors.lastname: Jiang
authors.forename: H
authors.initials: H
authors.lastname: Min
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications* / Q000473:pathology; D014463:Ultrasonography; D020255:Vitreous Detachment / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology