title: Intestinal Candida phospholipase is not elevated in patients with antibiotic-associated diarrhea.
abstract: In order to assess the role of Candida-secreted phospholipase in antibiotic-associated diarrhea (AAD), 43 fecal Candida isolates from patients with AAD and from controls were tested on egg yolk agar for production of phospholipase. Phospholipase zones did not differ between the isolates from patients with AAD and from controls. The data indicate that the fungal virulence factor phospholipase may not be responsible for AAD in adults.
authors.affiliation: Department of Internal Medicine, Karl-Franzens University, Graz, Austria. robert.krause@kfunigraz.ac.at
authors.forename: Robert
authors.initials: R
authors.lastname: Krause
authors.forename: Renate
authors.initials: R
authors.lastname: Haberl
authors.forename: Christina
authors.initials: C
authors.lastname: Strempfl
authors.forename: Florian
authors.initials: F
authors.lastname: Daxböck
authors.forename: Günter J
authors.initials: GJ
authors.lastname: Krejs
authors.forename: Emil C
authors.initials: EC
authors.lastname: Reisinger
authors.forename: Christoph
authors.initials: C
authors.lastname: Wenisch
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002175:Candida / Q000201:enzymology* / Q000472:pathogenicity; D002177:Candidiasis / Q000150:complications / Q000382:microbiology*; D003967:Diarrhea / Q000139:chemically induced* / Q000150:complications / Q000382:microbiology*; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D010740:Phospholipases / Q000032:analysis / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D010740:Phospholipases