The outcome of in vitro fertilization in advanced endometriosis with previous surgery: a case-controlled study.
OBJECTIVE
This study was undertaken to evaluate the outcome of in vitro fertilization (IVF) in patients with advanced pelvic endometriosis and previous surgical treatment.


METHODS
A case controlled study was performed.


RESULTS
Patients with the diagnosis of stage IV endometriosis with previous surgical treatment were treated by IVF (group A = 85). An age-matched group of patients (group B = 177) with tubal factor infertility were treated with the same protocol of IVF. In group A, cycle cancellation because of poor response occurred in 29.7% compared with 1.1% in the control group (relative risk 26.03, 95% CI 6.02-112.45). There were 13 (15.3%) clinical pregnancies per stimulated cycle in group A compared with 93 (52.5%) clinical pregnancies in the control group, P <.0001 (odds ratio 0.29, 95% CI 0.15-0.55).


CONCLUSIONS
The outcome of IVF in stage IV endometriosis with previous surgery was significantly lower compared with an age-matched group of tubal factor infertility.
Aboulghar
Mohamed A
MA
Egyptian IVF-ET Center, Hadaek Al Maadi, Cairo, Egypt. ivf@link.net
Mansour
Ragaa T
RT
Serour
Gamal I
GI
Al-Inany
Hesham G
HG
Aboulghar
Mona M
MM
D000328:Adult; D016022:Case-Control Studies; D004624:Embryo Transfer; D004715:Endometriosis / Q000150:complications*; D005184:Fallopian Tube Diseases / Q000150:complications; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D016896:Treatment Outcome