[The research of 10-hydroxy-2-decenoic acid on experiment hyperlipoidemic rat].
OBJECTIVE
To study the pharmacological effect of 10-hydroxy-2-decenoic acid(10-HDA) in experiment hyperlipoidemic rat.


METHODS
Preventive and therapeutic effects of 10-HDA were tested on hyperlioidemic rat model induced by high fat food.


RESULTS
10-HDA could reduce the content of TC, TG and beta-lioprotein, raise the content of HDL, which showed 10-HDA had preventive and therapeutic effects on hyperlipoidemic rat.


CONCLUSIONS
10-HDA was functional factor of preventive and therapeutic effects of royal jelly on hyperlipoidemia.
Xu
Donghui
D
Department of Pharmacy, Zhongshan University, Guangzhou 510275.
Mei
Xueting
X
Xu
Shibo
S
D000818:Animals; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005227:Fatty Acids / Q000737:chemistry*; D005229:Fatty Acids, Monounsaturated / Q000302:isolation & purification / Q000494:pharmacology*; D006949:Hyperlipidemias / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008419:Materia Medica / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D014280:Triglycerides / Q000097:blood; D000099219:Royal Jelly
D002784:Cholesterol; D008076:Cholesterol, HDL; D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D008077:Lipoproteins, LDL; D008419:Materia Medica; D014280:Triglycerides; D000099219:Royal Jelly; C055543:10-hydroxy-2-decenoic acid