[Effect of Cordyceps sinensis on the Th1/Th2 cytokines in patients with Condyloma Acuminatum].
OBJECTIVE
To investigate the effect of cordyceps sinensis (CS) on the Th1/Th 2 cytokines and recurrence in patients with Condyloma Acuminatum (CA).


METHODS
Double-antibody sandwich ELISA was used to study the serum level of IL-2 and IL-10 in 34 patients treated with CS(CS group) and 29 patients in control group. The recurrence rate of CA was observed.


RESULTS
After treated with CS, the serum levels of IL-2 and IL-10 significantly increased and decreased respectively (P < 0.05 or 0.01). No significant change occurred in control group. The recurrence times of CA in patients of CS group after electrocauterization were significantly lower than control group (P < 0.05).


CONCLUSIONS
CS might recover the balance of Th1/Th2 cytokines and enhance Th 1 immune response in patients with CA, and reduced the recurrence of CA.
Gao
Q
Q
First Affiliated Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou 510080.
Wu
G
G
He
D
D
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D003218:Condylomata Acuminata / Q000276:immunology*; D032661:Cordyceps; D006801:Humans; D016753:Interleukin-10 / Q000097:blood*; D007376:Interleukin-2 / Q000097:blood*; D007915:Lepidoptera / Q000382:microbiology; D055502:Secondary Prevention; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology
D000276:Adjuvants, Immunologic; D007376:Interleukin-2; D016753:Interleukin-10