Anti-PLA2 action test of Casearia sylvestris Sw.
Casearia sylvestris (Flacourtiaceae) is a plant which grows in the wild. The crude extract and pure substances from this plant induced partial inhibition of the PLA: (phospholipase A2) activity of snake venoms and some purified toxins. C. sylvestris extract efficiently neutralized the hemorrhagic and myotoxic activities caused by crude venoms and toxins.
Raslan
D S
DS
Departamento de Bioquímica e Imunologia-ICB, Laboratório de Venenos e Toxinas Animais, Universidade Federal de Minas Gerais (UFMG), Brazil.
Jamal
C M
CM
Duarte
D S
DS
Borges
M H
MH
De Lima
M E
ME
D000818:Animals; D001938:Brazil; D037821:Casearia / Q000737:chemistry*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control; D009135:Muscular Diseases / Q000139:chemically induced / Q000517:prevention & control; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D054467:Phospholipases A2; D010936:Plant Extracts / Q000494:pharmacology; D012910:Snake Venoms / Q000037:antagonists & inhibitors / Q000201:enzymology / Q000633:toxicity
D004791:Enzyme Inhibitors; D010936:Plant Extracts; D012910:Snake Venoms; D010741:Phospholipases A; D054467:Phospholipases A2