title: Knowledge of antiretroviral regimen dosing and adherence: a longitudinal study.
abstract: In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.
authors.affiliation: Division of Infectious Diseases, Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance 90502, USA. lgmiller@ucla.edu
authors.forename: Loren G
authors.initials: LG
authors.lastname: Miller
authors.forename: Honghu
authors.initials: H
authors.lastname: Liu
authors.forename: Ron D
authors.initials: RD
authors.lastname: Hays
authors.forename: Carol E
authors.initials: CE
authors.lastname: Golin
authors.forename: Zhishen
authors.initials: Z
authors.lastname: Ye
authors.forename: C Keith
authors.initials: CK
authors.lastname: Beck
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Kaplan
authors.forename: Neil S
authors.initials: NS
authors.lastname: Wenger
mesh_terms: D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010349:Patient Compliance
chemical_list: D019380:Anti-HIV Agents