A comparative study of hypertonic saline, daily and alternate-day rhDNase in children with cystic fibrosis.
Suri
R
R
Respiratory Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK.
Wallis
C
C
Bush
A
A
Thompson
S
S
Normand
C
C
Flather
M
M
Grieve
R
R
Metcalfe
C
C
Lees
B
B
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D018592:Cross-Over Studies; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000191:economics*; D003850:Deoxyribonuclease I / Q000008:administration & dosage* / Q000191:economics; D004334:Drug Administration Schedule; D017079:Exercise Tolerance / Q000187:drug effects; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D017048:Health Care Costs; D006801:Humans; D008297:Male; D017059:Models, Econometric; D009330:Nebulizers and Vaporizers; D010349:Patient Compliance; D011788:Quality of Life; D011994:Recombinant Proteins / Q000008:administration & dosage* / Q000191:economics; D012044:Regression Analysis; D012462:Saline Solution, Hypertonic / Q000191:economics / Q000627:therapeutic use*; D018709:Statistics, Nonparametric; D014797:Vital Capacity / Q000187:drug effects
D011994:Recombinant Proteins; D012462:Saline Solution, Hypertonic; C085693:DNASE1 protein, human; D003850:Deoxyribonuclease I