title: Maximum intensity projection analysis in magnetic resonance of the breast.
abstract: The aim of this study was to determine the sensitivity, specificity and accuracy of vascular asymmetries and vessel location seen using MR Maximum Intensity Projection imaging for malignant and benign lesions. We enrolled 101 women, with an age ranging from 29 to 69 years (mean age of 53.1 years), with a mammary nodule and candidate for surgical intervention. MR was carried out using a 1.5 Tesla superconductive magnet, equipped with a double and bilateral Phased Array dedicated coil. All images obtained were processed using MIP. The relationship between an asymmetry due to a greater amount of vascular structures in the breast with a malignant neoplasm and symmetry with benign neoplasms were statistically significant (p < 0.001): sensitivity of 71.8%, specificity 100% and accuracy 76.2%. The relationship between perilesional or intralesional vessels with malignant versus benign neoplasms were statistically significant (p < 0.001): sensitivity 88.5%, specificity 82.6% and accuracy 87.1%. We concluded that asymmetries between breasts and the presence of perilesional or intralesional vessels seen in MIP images are important signs and, therefore, must be reported.
authors.affiliation: Dipartimento di Scienze Cliniche e di Bioimmagini, Università G. D'Annunzio, Chieti, Italy. pamattei@unich.it
authors.forename: A
authors.initials: A
authors.lastname: Carriero
authors.forename: A
authors.initials: A
authors.lastname: Di Credico
authors.forename: M
authors.initials: M
authors.lastname: Mansour
authors.forename: L
authors.initials: L
authors.lastname: Bonomo
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis* / Q000473:pathology