[Effect of Ce3+ on reactive oxygen species in cells].
The effect of Ce3+ on the content of (reactive oxygen species ROS) in hepatocytes and V79 cells was studied with microfluorometry. The results showed that Ce3+ could enhance the concentration of ROS in hepatocytes in high dose and reduce the concentration of ROS in low dose. These results suggested that Ce3+ might decrease the damage of lipid peroxidation and DNA in low dose and might increase the damage of lipid peroxidaion and DNA in high dose.
Shen
Z
Z
Shenzhen Hygiene and Epidemics Station, Shenzhen 518020, China.
Zhuang
Z
Z
Huang
H
H
Zhang
J
J
D000818:Animals; D002478:Cells, Cultured; D002563:Cerium / Q000494:pharmacology*; D005347:Fibroblasts / Q000378:metabolism; D005470:Fluorometry / Q000379:methods; D022781:Hepatocytes / Q000378:metabolism*; D008168:Lung / Q000166:cytology; D051381:Rats; D017207:Rats, Sprague-Dawley; D017382:Reactive Oxygen Species / Q000378:metabolism*
D017382:Reactive Oxygen Species; D002563:Cerium