[Study on stroke syndrome of Chinese medicine and its relationship with blood hypercoagulative status and insulin resistance in diabetic ischemic stroke patients].
OBJECTIVE
To study the relationship of TCM Syndromes, involving Viscera Syndrome and involving Meridian Syndrome, with blood hypercoagulative state and insulin resistance in patients with diabetic ischemic stroke.


METHODS
Insulin sensitivity index (ISI) could reflect the insulin resistance, and those reflecting blood hypercoagulative state parameters such as platelet agglutination test (PAgT), fibrinogen (FG), in vitro thrombus length (VTL) and activating partial thrombinogen time (APTT), were used to expound and prove the relationship with the stroke syndrome.


RESULTS
The symptom scores, PAgT, VTL, FG levels in patients involved with Viscera Syndromes (including those of Wind Syndrome, Phlegm-Dampness Syndrome, Heat-Fire Syndrome and Yin-deficiency with Yang-excess Syndrome) were significantly higher than those in patients involved with Meridian Syndromes (P < 0.05 or P < 0.01), while the ISI level in the former was lower than that in the latter (P < 0.01).


CONCLUSIONS
There is close relationship between blood hypercoagulative state, insulin resistance and TCM Stroke Syndromes in patients with diabetic ischemic stroke.
Li
Chuang-peng
CP
Zhuhai TCM Hospital Affiliated to Guangzhou University of TCM, Guangdong 519015.
Chen
Jian-fei
JF
Pen
Min
M
D000368:Aged; D000369:Aged, 80 and over; D001809:Blood Viscosity; D003929:Diabetic Neuropathies / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D010974:Platelet Aggregation; D020521:Stroke / Q000097:blood*
D005340:Fibrinogen