title: [Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats].
abstract: OBJECTIVE
  To investigate the preventive effect of Jiangu granule (JGG) on experimental primary osteoporosis type I.
  
  
  METHODS
  Osteoporosis model was established through ovary resection of female rats. Bone mineral density (BMD) was measured with double energy X-ray absorptiometry. Level of endocrine markers, including osteocalcin (BGP), estradiol (E2) and calcitonin (CT) in serum were examined by RIA. And uterus parameters was calculated also.
  
  
  RESULTS
  JGG could significantly increase BMD and uterus index, improve the levels of E2 and CT in serum, at the same time reduce the BGP level.
  
  
  CONCLUSIONS
  JGG can efficiently prevent type I primary osteoporosis or delay its occurrence by enhancing the function of endocrine system, coordinating the action of calcium related hormone, reducing bone turnover rate and increasing BMD.
authors.affiliation: Faculty of Orthopedics and Traumatology, Fujian College of TCM, Fuzhou 350003.
authors.forename: Yan-ping
authors.initials: YP
authors.lastname: Lin
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Ma
authors.forename: Er-you
authors.initials: EY
authors.lastname: Feng
mesh_terms: D000818:Animals; D015519:Bone Density; D002116:Calcitonin / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004958:Estradiol / Q000097:blood; D005260:Female; D015675:Osteocalcin / Q000097:blood*; D010024:Osteoporosis / Q000097:blood / Q000517:prevention & control*; D010052:Ovariectomy; D008517:Phytotherapy; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal; D015675:Osteocalcin; D004958:Estradiol; D002116:Calcitonin