[Studies on the feasibility of detecting circulating antibodies in saliva of Schistosoma japonicum infected rabbits].
OBJECTIVE
To investigate the feasibility of detecting anti-Schistosoma japonicum antibodies in saliva.


METHODS
Saliva and serum samples of 5 infected, 7 reinfected and 8 treated rabbits were collected at different times periods. The CAb in saliva and serum was detected by using ELISA.


RESULTS
The sensitivity of ELISA was 94.7% for saliva and 100% for serum. The specificity of ELISA was 100% for both saliva and serum.


CONCLUSIONS
Saliva can be used to detect circulating antibodies for the diagnosis of schistosomiasis japonica.
Wang
Z
Z
Department of Parasitology, Shanghai Second Medical University, Shanghai 200025.
Lou
W
W
Zhang
E
E
Zhang
X
X
Xue
C
C
D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis* / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005240:Feasibility Studies; D011817:Rabbits; D012463:Saliva / Q000276:immunology*; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000175:diagnosis*
D000909:Antibodies, Helminth