Selecting a systemic corticosteroid for acute asthma in young children.
Oral corticosteroids are as effective as intravenous therapy for treating acute exacerbations of asthma. They are available in tablets that can be crushed and mixed with soft food or syrup, and in a variety of liquid formulations that differ in volume required, palatability, patient acceptance, and cost. The most important consideration in product selection for a young child is that the doses can be easily swallowed and retained.
Hendeles
Leslie
L
Department of Pharmacy Practice, College of Pharmacy, The University of Florida, Gainesville 32610, USA. hendeles@cop.ufl.edu
D000208:Acute Disease; D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001249:Asthma / Q000188:drug therapy* / Q000517:prevention & control; D001682:Biological Availability; D002648:Child; D003907:Dexamethasone / Q000008:administration & dosage* / Q000493:pharmacokinetics; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000493:pharmacokinetics; D011239:Prednisolone / Q000008:administration & dosage* / Q000493:pharmacokinetics; D011241:Prednisone / Q000008:administration & dosage* / Q000493:pharmacokinetics; D016032:Randomized Controlled Trials as Topic; D013649:Taste
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D003907:Dexamethasone; D011239:Prednisolone; D011241:Prednisone; D008775:Methylprednisolone