[Experimental studies on pharmacodynamic effect of Macleaya cordata].
The pharmacodynamic effect of Macleaya cordata was investigated in this study. The results showed that Macleaya cordata could improve liver function of acute hepatic injuries in rats caused by tetrachloromethan or galactoslmine. Macleaya cordata could lessen the level of serum LDH and mortality of rats, increase ratio of serum A/G, protect cellular membrane efectively and inhibit fibrosis in rats with chromic heptic injury caused by tetrachloromethane. Macleaya cordata still enhanced the function of T and B lymphocytes.
Yang
J
J
Anhui Institute of Medical Sciences, Hefei 230061.
Wang
J
J
Liu
X
X
Fang
X
X
D000418:Albumins / Q000378:metabolism; D000818:Animals; D002252:Carbon Tetrachloride Poisoning; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood* / Q000209:etiology / Q000276:immunology; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005688:Galactosamine; D005916:Globulins / Q000378:metabolism; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008111:Liver Function Tests; D008297:Male; D051379:Mice; D028101:Papaveraceae / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D000418:Albumins; D004365:Drugs, Chinese Herbal; D005916:Globulins; D005688:Galactosamine; D007770:L-Lactate Dehydrogenase