title: The evaluation of reno- and hepatoprotective effects of huai-shan-yao (Rhizome Dioscoreae).
abstract: Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.
authors.affiliation: Department of Food Science, National Chung Hsing University, Taichung, Taiwan, ROC.
authors.forename: Shih-Chang
authors.initials: SC
authors.lastname: Lee
authors.forename: Chin-Chun
authors.initials: CC
authors.lastname: Tsai
authors.forename: Jung-Chou
authors.initials: JC
authors.lastname: Chen
authors.forename: Chun-Ching
authors.initials: CC
authors.lastname: Lin
authors.forename: Miao-Lin
authors.initials: ML
authors.lastname: Hu
authors.forename: Shin
authors.initials: S
authors.lastname: Lu
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D002492:Central Nervous System Depressants / Q000633:toxicity; D027742:Dioscorea / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D000431:Ethanol / Q000633:toxicity; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D007677:Kidney Function Tests; D008099:Liver / Q000473:pathology; D008108:Liver Diseases, Alcoholic / Q000473:pathology / Q000517:prevention & control*; D008111:Liver Function Tests; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012838:Silymarin / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D002492:Central Nervous System Depressants; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D012838:Silymarin; C473661:huai-shan-yao; D000431:Ethanol