[Pluripotential of human adult stem cells and its application in reparative and reconstructive surgery].
OBJECTIVE
To explore the pluripotential and possible clinical application of adult stem cells.


METHODS
The original articles on adult stem cells were extensively reviewed and the recent advances were summed up.


RESULTS
Adult stem cells were located at different tissues of human beings and had the pluripotentiality of self-renewal and differentiation. Some adult stem cells, such as in marrow, nerve, muscle, fat, skin, liver, tissues, had the ability to differentiate into the unrelated cell type.


CONCLUSIONS
The pluripotential, ubiquitous distribution and plasticity of adult stem cells offered a new way in regeneration medicine, such as cell therapy and tissue engineering.
Pan
Xing-hua
XH
Department of Hematology, Zhujiang Hospital, First Military Medical Science University, Guangzhou, Guangdong, P. R. China 510282.
Han
Yi-bing
YB
Guo
Kun-yuan
KY
D002454:Cell Differentiation; D002478:Cells, Cultured; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D008099:Liver / Q000166:cytology; D019651:Plastic Surgery Procedures; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D023822:Tissue Engineering