title: [Clinical features and changing trends of bacterial liver abscess: analysis of 48 cases].
abstract: OBJECTIVE
  To analyse and compare the changing of clinical feature, pathogenic bacteria, and so is diagnosis and treatment of bacterial liver abscess up date.
  
  
  METHODS
  Retrospective study of forty-eight patients over 10 years in PUMC hospital.
  
  
  RESULTS
  Compared with the patients in 1960s, the complication and mortality of this disease decreased remarkably. The main clinical manifestations and signs became less typical. Cholelithes and tumor of biliary tract instead of biliary ascariasis became chief pathogenic factor (29.2%). Patients with diabetes mellitus complicating bacterial liver abscess tended to increase (8.3%). The case with negative bacterial culture has increased (52.1%). Ultrasonography should be the first choice for diagnosis, the confirmed diagnosis rate is 79.2%. Percutaneous drainage of the abscess and combined using antibiotics are the effective treatment method. Septic shock was the chief complication causing death.
  
  
  CONCLUSIONS
  This disease becomes less typical and difficult to early diagnosis attention should be paid to clinical medicine.
authors.affiliation: Department of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing 100730.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Qian
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000628:therapy; D008100:Liver Abscess / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies