title: Gliofibrous nodule in the cerebello-medullary fissure.
abstract: An extra-axial nodule in the cerebello-medullary fissure is described, occurring in a 27-year-old-woman. MRI and CT scans revealed the lesion was a non-enhanced round mass, which was associated with mild atrophy of the surrounding cerebellum, but with no perifocal edema. In the surgical observation, the mass was white, elastic and hard, well demarcated and localized in the cerebello-medullary fissure. Histologically, the lesion was composed of astrocytes and collagen-producing fibroblasts with no anaplasia. These findings suggested that the lesion was hamartomatous, but not neoplastic. This type of gliofibrous nodule has not been previously reported.
authors.affiliation: Department of Neurosurgery, Keio University School of Medicine, Shinanomachi, Tokyo, Japan. kazrmky@sc.itc.keio.ac.jp
authors.forename: Kazunari
authors.initials: K
authors.lastname: Yoshida
authors.forename: Kenji
authors.initials: K
authors.lastname: Hiraga
authors.forename: Hisatsugu
authors.initials: H
authors.lastname: Ishimori
authors.forename: Makoto
authors.initials: M
authors.lastname: Katayama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawase
authors.forename: Eiji
authors.initials: E
authors.lastname: Ikeda
authors.forename: Makio
authors.initials: M
authors.lastname: Mukai
mesh_terms: D000328:Adult; D001253:Astrocytes / Q000473:pathology; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D006222:Hamartoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008526:Medulla Oblongata / Q000473:pathology; D014057:Tomography, X-Ray Computed