title: [Gene frequencies of 4 STR loci in Tibetan population of Yunnan province].
abstract: OBJECTIVE
  To investigate the gene frequencies of 4 STR loci in Tibetan population of Yunnan.
  
  
  METHODS
  Multiple polymerase chain reaction (PCR), denaturing polyacrylamide gel electrophoresis and silver staining were used to detect D21S11, D8S1179, D16S539 and LPL loci. DNA samples collected from 105 unrelated Tibetan individuals in Yunnan province were analyzed.
  
  
  RESULTS
  At D21S11, D8S1179, D16S539 and LPL loci, 13, 8, 7, 6 alleles and 33, 21, 16 and 9 genotypes were observed, respectively. The genotype distribution of the 4 STR was in accordance with the Hardy-Weinberg equilibrium.
  
  
  CONCLUSIONS
  The high combined discrimination power and exclusion power of the four loci in Tibetan population make multi-PCR detection a valuable tool for forensic identity, genetics and anthropology.
authors.affiliation: Yuxi Public Security Bureau of Yunnan Province, Yuxi, PR China.
authors.forename: Bao-wen
authors.initials: BW
authors.lastname: Cheng
authors.forename: Chun-jie
authors.initials: CJ
authors.lastname: Xiao
mesh_terms: D000483:Alleles; D002681:China; D004247:DNA / Q000235:genetics; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D008071:Lipoprotein Lipase / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D020080:Tandem Repeat Sequences / Q000235:genetics*; D018609:Tibet / Q000208:ethnology
chemical_list: D004247:DNA; D008071:Lipoprotein Lipase