title: Gender differences in the association of adult hopelessness with adverse childhood experiences.
abstract: BACKGROUND
  The impact of childhood traumatic events on long-term psychological development has been widely studied. Nevertheless, little research has been carried out on possible associations between adverse childhood experiences (ACEs) and hopelessness in adulthood, and whether any gender differences exist.
  
  
  OBJECTIVE
  The aim of this study was to examine the association between ACEs (poor relationship between parents, unhappiness of childhood home, hard parenting, physical punishment, domestic violence, alcohol abuse in primary family) and current hopelessness without any mental disorder in a general population sample.
  
  
  METHODS
  1598 adults (43 % were men), aged 25-64 years, completed self-report measures to assess ACEs and hopelessness by means of the Beck Hopelessness Scale (HS). Logistic regression was used to adjust for the effects of sociodemographic factors on the association between the cumulative number of ACEs and hopelessness.
  
  
  RESULTS
  Whereas several bivariate associations were found between ACEs and hopelessness, none of them remained significant in multivariate analysis. However, men who reported three or more ACEs were 2.79 times (95 % CI 1.17-6.63) and women 2.19 times (95 % CI 1.04-4.65) more likely to be hopeless compared with those without any ACEs. In women (OR 2.25, 95 % CI 1.01-5.00), but not in men, this relationship remained significant after adjusting for several current covariates.
  
  
  CONCLUSIONS
  Clustering of ACEs may have long-lasting effects by increasing the risk of hopelessness in adulthood, especially in women. Increased awareness of the frequency of ACEs and their subsequent consequences, such as hopelessness, may encourage health care professionals to undertake preventive work in primary and mental health care.
authors.affiliation: Research and Development Unit 4977, Department of Psychiatry, Kuopio University Hospital, P. O. Box 1777, 70211 Kuopio, Finland. kaisa.haatainen@kuh.fi
authors.forename: K M
authors.initials: KM
authors.lastname: Haatainen
authors.forename: A
authors.initials: A
authors.lastname: Tanskanen
authors.forename: J
authors.initials: J
authors.lastname: Kylmä
authors.forename: K
authors.initials: K
authors.lastname: Honkalampi
authors.forename: H
authors.initials: H
authors.lastname: Koivumaa-Honkanen
authors.forename: J
authors.initials: J
authors.lastname: Hintikka
authors.forename: R
authors.initials: R
authors.lastname: Antikainen
authors.forename: H
authors.initials: H
authors.lastname: Viinamäki
mesh_terms: D000328:Adult; D002649:Child Abuse / Q000523:psychology* / Q000706:statistics & numerical data; D002675:Child, Preschool; D003863:Depression / Q000453:epidemiology* / Q000523:psychology; D004644:Emotions; D005195:Family Relations; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D009341:Negativism; D011788:Quality of Life; D012737:Sex Factors