title: A case of acute pneumonitis induced by injection of silicone for colpoplasty.
abstract: Silicone fluid (polymethylsiloxane) is a liquid polymer that had been widely used in breast augmentation and other cosmetic procedures. However, many adverse reactions after silicone injections into human beings have been reported including adverse pulmonary sequelae. We report a case of a 46-year-old woman who suffered from acute pneumonitis that was induced by illicit injection of silicone into the vaginal wall for colpoplasty. The pulmonary involvement was documented by transbronchial lung biopsy and bronchoalveolar lavage where examination with the electron microscope disclosed the presence of large quantities of pleomorphic cytoplasmic inclusions in alveolar macrophages. Clinicians should be aware of this unusual complication of injection of silicone.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine and Lung Institute, Medical Research Center, Seoul National University, Seoul, Korea.
authors.forename: Cheol Hyeon
authors.initials: CH
authors.lastname: Kim
authors.forename: Doo Hyun
authors.initials: DH
authors.lastname: Chung
authors.forename: Chul-Gyu
authors.initials: CG
authors.lastname: Yoo
authors.forename: Choon-Taek
authors.initials: CT
authors.lastname: Lee
authors.forename: Sung Koo
authors.initials: SK
authors.lastname: Han
authors.forename: Young-Soo
authors.initials: YS
authors.lastname: Shim
authors.forename: Young Whan
authors.initials: YW
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D005260:Female; D005782:Gels / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced*; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*; D014621:Vagina / Q000601:surgery
chemical_list: D005782:Gels; D012828:Silicones; C078211:polymethylsiloxane