A novel titanium-catalyzed cyclization of olefinic iodoethers to tetrahydrofurans.
A catalytic reductive cyclization of olefinic iodoethers was achieved by use of cat. Cp(2)TiCl(2) in the presence of Mn and Me(3)SiCl. This protocol provides a versatile method for the selective formation of multisubstituted tetrahydrofurans.
Zhou
Longhu
L
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Yamada-oka, Suita, Osaka 565-0871, Japan.
Hirao
Toshikazu
T