title: [Application of single cell gelelectrophoresis assay in environmental hygiene].
abstract: The single cell gelelctrophoresis assay is a rapid, simple and sensitive technique for measuring DNA damage and repair at the single cell level. It is introduced into environmental hygiene and plays an important role in many aspects such as detecting and evaluating the genotoxity of environmental toxic substances. In this paper, the underlying principles of this assay in detecting DNA damage and repair, and its application in environmental hygiene are reviewed.
authors.affiliation: School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Qiangzheng
authors.initials: Q
authors.lastname: Sun
authors.forename: Wenqing
authors.initials: W
authors.lastname: Lu
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D000818:Animals; D020552:Comet Assay; D004247:DNA / Q000032:analysis; D004249:DNA Damage; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D011827:Radiation
chemical_list: D000393:Air Pollutants; D004247:DNA