title: Synthesis of some new azoles and azines and their condensed derivatives.
abstract: Ethyl (2,5-Dimethylphenyl) pyruvate (2) condensed with o-phenylenediamine, ethylenediamine, semicarbazide and thiosemicarbazide and gave quinoxaline derivative (3), dihydropyrazine derivative (9) and 1,2,4-triazine derivatives (10, 11) respectively. Compound (3) reacted with phosphorous pentasulphide, polyphosphoric acid, semicarbazide hydrochloride and phenylisothiocyanate yielded thienoquinoxaline derivative (4), furoquinoxaline derivative (5), semicarbazone derivative (6) and pyrrole derivative (15) respectively. Reaction of (2) with hydrazines and malononitrile afforded the arylpyrazole derivatives (12a, b) and pyrane derivative (13) respectively. Heterocyclization of compound (6) afforded thiadiazole and selenodiazole derivatives (7), (8).
authors.affiliation: Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.
authors.forename: Gamal A
authors.initials: GA
authors.lastname: Ahmed
mesh_terms: D001393:Azoles / Q000138:chemical synthesis* / Q000737:chemistry; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight; D011719:Pyrazines / Q000138:chemical synthesis* / Q000737:chemistry; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001393:Azoles; D007202:Indicators and Reagents; D011719:Pyrazines; D014227:Triazines