[Serum phospholipids and processes of cholesterol esterification in the European North].
Lipid profile was studied in blood serum of 146 European northerns (trans-polar Nenets Autonomous district and Archangelsk). Monolayer chromatography was used to determine sphingomyelin (SP), phosphatidyl ethanolamine, phosphatidylcholine (PC), lisophosphatidylcholine, glycerophosphatides and phosphatide acides. The northerns were found to have very low concentrations of blood PC. At the same time, the NAD population have a little higher SP which may play an adaptive role in terms of the cell membrane function. The transpolar natives appear to possess an adaptive mechanism of increasing total cholesterol and reducing cholesterol of high-density lipoproteins, and activation of cholesterol esterification resulting in decrease in the free cholesterol fraction in serum.
Boĭko
E R
ER
Bichkaeva
F A
FA
Tkachev
A V
AV
D000222:Adaptation, Physiological / Q000502:physiology; D002391:Catchment Area, Health; D002788:Cholesterol Esters / Q000097:blood*; D002855:Chromatography, Thin Layer; D004951:Esterification; D005260:Female; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000097:blood / Q000209:etiology; D010743:Phospholipids / Q000097:blood*; D012307:Risk Factors; D012426:Russia
D002788:Cholesterol Esters; D010743:Phospholipids