[Clinical observation on treatment of ulcerative colitis by soothing liver and activating spleen].
OBJECTIVE
To observe the effect of soothing Liver and activating Spleen method (SLAS) of TCM in treating ulcerative colitis (UC).


METHODS
Patients were randomly divided into 2 groups, the 33 cases in the treated group were treated with Ningxie Powder (NXP) and the 30 cases in the control group were treated with salicylazosulfapyridine (SASP). The improvement in clinical symptoms scoring, therapeutic effect in various treatment courses, changes in immune indexes as well as the condition in 1-year follow-up were observed.


RESULTS
The initial therapeutic effect after 3 months treatment showed insignificant difference between the two groups. However, the effect in the treated group was better than that in the control group both short-term (after 9 months treatment) and long-term (for 1-year follow-up study) (P < 0.05).


CONCLUSIONS
NXP, a Chinese herbal drug for soothing Liver and activating Spleen, shows good and persistent effect in treating ulcerative colitis and has favorable prospect in application.
Cheng
W J
WJ
Medical Department of Digestive Diseases, First Affiliated Hospital of Anhui College of TCM, Hefei 230031.
D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011208:Powders; D012460:Sulfasalazine / Q000627:therapeutic use
D000890:Anti-Infective Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D011208:Powders; D012460:Sulfasalazine