[Effects of Curcuma phaeocaulis on learning and memory and lipid peroxide in mice].
Nine months mice were inoculated and the method of water maze test and lipid peroxide determination to study the effects of extract of Curcuma phaeocaulis Valeton on learning and memory ability and retarding of senescence. Results showed that in water maze test the time for the group with Curcuma phaeocaulis Valeton needed from initial position to the end was significantly shortened compared with old control. The error numbers for the group of Curcuma phaeocaulis Valeton were significantly decreased compared with old control after starting experiment for 18 days and 24 days and for 35 days no significance difference was showed between groups. The levels of brain, liver and red blood cells lipid peroxide in the group with Curcuma phaeocaulis Valeton were considerably lower than old control, hemoglobin content was considerably increased than old control.
Li
L
L
Medical College, Yanbian University, Yanji 133000.
Han
C
C
Cui
S
S
Qiu
D
D
Piao
K
K
Xuan
F
F
D000375:Aging / Q000187:drug effects; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D030024:Curcuma / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D008054:Lipid Peroxides / Q000097:blood* / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D018782:Maze Learning; D008568:Memory / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D006454:Hemoglobins; D008054:Lipid Peroxides; D010936:Plant Extracts