[Influence of arginine on the renal functional condition of rats in sublimate nephropathy].
On a background of sublimate nephropathy there was studied the influence of arginin introduction on renal functional condition of white rats. Is established, that the dosage of arginin chloride 300 mg/kg of body weight at in 24 hours after sublimate introduction decreases the kidneys damage and expression of retention azotemia. The positive arginin action in sublimate nephropathy is shown the increasing of glomerular filtration rate and proteinuria decrease. Arginin does not influence on expression of sublimate infringement of kidney Na-transport, and increases it filtrate a charge and renal excretion of present cation.
Hozhenko
A I
AI
Fedoruk
O S
OS
Pohorila
I V
IV
D000818:Animals; D001120:Arginine / Q000627:therapeutic use*; D004195:Disease Models, Animal; D005919:Glomerular Filtration Rate / Q000187:drug effects*; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D007677:Kidney Function Tests; D008297:Male; D008627:Mercuric Chloride; D009393:Nephritis / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D011507:Proteinuria / Q000209:etiology / Q000517:prevention & control; D051381:Rats; D014511:Uremia / Q000209:etiology / Q000517:prevention & control
D008627:Mercuric Chloride; D001120:Arginine