Dialectical behaviour therapy for women with borderline personality disorder: 12-month, randomised clinical trial in The Netherlands.
BACKGROUND
Dialectical behaviour therapy (DBT) is widely considered to be a promising treatment for borderline personality disorder (BPD). However, the evidence for its efficacy published thus far should be regarded as preliminary.


OBJECTIVE
To compare the effectiveness of DBT with treatment as usual for patients with BPD and to examine the impact of baseline severity on effectiveness.


METHODS
Fifty-eight women with BPD were randomly assigned to either 12 months of DBT or usual treatment in a randomised controlled study. Participants were recruited through clinical referrals from both addiction treatment and psychiatric services. Outcome measures included treatment retention and the course of suicidal, self-mutilating and self-damaging impulsive behaviours.


RESULTS
Dialectical behaviour therapy resulted in better retention rates and greater reductions of self-mutilating and self-damaging impulsive behaviours compared with usual treatment, especially among those with a history of frequent self-mutilation.


CONCLUSIONS
Dialectical behaviour therapy is superior to usual treatment in reducing high-risk behaviours in patients with BPD.
Verheul
Roel
R
DeViersprong Center of Psychotherapy, University of Amsterdam, Halsteren, The Netherlands. roel.verheul@deviersprong.net
Van Den Bosch
Louise M C
LM
Koeter
Maarten W J
MW
De Ridder
Maria A J
MA
Stijnen
Theo
T
Van Den Brink
Wim
W
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001521:Behavior Therapy / Q000379:methods*; D001883:Borderline Personality Disorder / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010349:Patient Compliance; D011569:Psychiatric Status Rating Scales; D016728:Self-Injurious Behavior / Q000517:prevention & control; D013406:Suicide, Attempted / Q000517:prevention & control; D016896:Treatment Outcome
D014150:Antipsychotic Agents