Mobile genetic elements colonizing the genomes of metazoan parasites.
A substantial fraction of the genome of most eukaryotes, including those of metazoan parasites, is predicted to comprise repetitive sequences. Mobile genetic elements (MGEs) will make up much of these repetitive sequences, particularly the interspersed sequences. This article reviews information on MGEs that have colonized the genomes of metazoan parasites (i.e. parasites of parasites). Helminth and mosquito genomes, in particular, are compared with those of better-understood model organisms. MGEs from the genomes of metazoan parasites can be expected to have practical uses in transgenesis and epidemiological studies.
Brindley
Paul J
PJ
Dept of Tropical Medicine, Tulane University, Health Sciences Center, New Orleans, Louisiana 70112, USA. paul.brindley@tulane.edu
Laha
Thewarach
T
McManus
Donald P
DP
Loukas
Alex
A
D000818:Animals; D004251:DNA Transposable Elements / Q000235:genetics; D004175:Diptera / Q000235:genetics* / Q000469:parasitology; D019143:Evolution, Molecular; D016678:Genome; D006376:Helminths / Q000235:genetics*; D006790:Host-Parasite Interactions; D007303:Insect Vectors / Q000235:genetics* / Q000469:parasitology; D020071:Interspersed Repetitive Sequences; D018626:Retroelements / Q000235:genetics
D004251:DNA Transposable Elements; D018626:Retroelements