title: Meliternatin: a feeding deterrent and larvicidal polyoxygenated flavone from Melicope subunifoliolata.
abstract: We screened more than 60 Malaysian plants against two species of insects and found that Melicope subunifoliolata (Stapf) T.G. Hartley (Rutaceae) showed strong feeding deterrent activity against Sitophilus zeamais Motsch. (Curculionidae) and very good larvicidal activity against Aedes aegypti L. (Diptera). One anti-insect compound, meliternatin (3,5-dimethoxy-3',4',6,7-bismethylendioxyflavone) (6) and six other minor polyoxygenated flavones were isolated from M. subunifoliolata.
authors.affiliation: Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. dbshosh@nus.edu.sg
authors.forename: Shuit
authors.initials: S
authors.lastname: Hung Ho
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: K Y
authors.initials: KY
authors.lastname: Sim
authors.forename: Gwendoline C L
authors.initials: GC
authors.lastname: Ee
authors.forename: Zamrie
authors.initials: Z
authors.lastname: Imiyabir
authors.forename: K F
authors.initials: KF
authors.lastname: Yap
authors.forename: Khozirah
authors.initials: K
authors.lastname: Shaari
authors.forename: Swee
authors.initials: S
authors.lastname: Hock Goh
mesh_terms: D000330:Aedes / Q000254:growth & development; D000818:Animals; D001517:Coleoptera / Q000254:growth & development; D004435:Eating / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D007928:Lethal Dose 50; D019906:Nuclear Magnetic Resonance, Biomolecular; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D005419:Flavonoids; D007306:Insecticides; C474048:meliternatin