[Experimental study on decoctum Agrimonia pilosa Ledeb-induced apoptosis in HL-60 cells in vitro].
In this study, MTT assay, cell morphology and flow cytometry were used to explore Agrimonia pilosa Ledeb on HL-60 cells in vitro. The data suggested that Agrimonia pilosa Ledeb had the effects of growth inhibition in HL-60 cells. After treated with decoctum Agrimonia pilosa Ledeb, cells underwent apoptosis with typical morphological feature. DNA histograms by flow cytometric analysis displayed distinct apoptotic peak.
Gao
K
K
PLA Jinan Junior College of Medicine, Jinan 250022.
Zhou
L
L
Chen
J
J
Li
F
F
Zhang
L
L
D031981:Agrimonia / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005434:Flow Cytometry; D018922:HL-60 Cells; D006358:Hot Temperature; D006801:Humans
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal