title: Asian variant of CD5+ intravascular large B-cell lymphoma with splenic infarction.
abstract: A 57-year-old man was admitted with fever and epigastralgia, and presented with splenomegaly and pancytopenia. A CT scan revealed splenic infarctions. There were no lymphadenopathies, skin lesions, or neurological abnormalities. A splenectomy was performed. Bone marrow involvement with hemophagocytosis was noted. The diagnosis of Asian variant of intravascular diffuse large B-cell lymphoma was based on intravascular and sinusoidal distribution of large CD5+ B cells. The patient died of the disease 11 months after onset. To our knowledge, this is the first report of AIVL that presented with splenic infarction. This distinct lymphoma should be included in the differential diagnosis of splenic infarction.
authors.affiliation: Department of Internal Medicine, Nishio Municipal Hospital, 6 Kamiawara, Kumami-cho, Nishio 445-8510.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Tokura
authors.forename: Takuhei
authors.initials: T
authors.lastname: Murase
authors.forename: Takayuki
authors.initials: T
authors.lastname: Toriyama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Totani
authors.forename: Masataka
authors.initials: M
authors.lastname: Negita
authors.forename: Kaoru
authors.initials: K
authors.lastname: Akaza
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ozawa
authors.forename: Atsuko
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Shigeo
authors.initials: S
authors.lastname: Nakamura
mesh_terms: D001208:Asia; D002869:Chromosome Aberrations; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D008297:Male; D008875:Middle Aged; D013159:Splenic Infarction / Q000209:etiology*; D019043:Vascular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000235:genetics