title: Streptococcal antibodies among rural school children in Bangladesh.
abstract: The upper limit of normal values of group A streptococcal antibodies should be known for a population concerned because it is influenced by many local conditions. As yet the reference value of the these antibodies has not been determined by using a quantitative method among Bangladeshi children. We determined the reference value of anti-streptolysin O and anti-deoxyribonuclease B among 361 apparently healthy rural Bangladeshi primary school children (aged 5 to 14 years, mean 9.2 years). Anti-streptolysin O was measured by an auto-analyzer and antideoxyribonuclease B was measured by microtitre method. The geometric mean titres for the entire group was 241 IU/ml and 222 IU/ml for anti-streptolysin O and anti-deoxyribonuclease B respectively. The upper limit of normal values (80th percentile) was 390 and 340 for anti-streptolysin O and anti-deoxyribonuclease B, respectively. These limits should be of value to physicians, epidemiologists and clinical laboratory personnel as well.
authors.affiliation: National Center for Control of Rheumatic Fever and Heart Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh.
authors.forename: M M
authors.initials: MM
authors.lastname: Zaman
authors.forename: M M M
authors.initials: MM
authors.lastname: Hassan
authors.forename: J
authors.initials: J
authors.lastname: Ahmed
authors.forename: S
authors.initials: S
authors.lastname: Zareen
authors.forename: M Q
authors.initials: MQ
authors.lastname: Jalil
authors.forename: N
authors.initials: N
authors.lastname: Eshaque
authors.forename: R
authors.initials: R
authors.lastname: Khanom
authors.forename: A
authors.initials: A
authors.lastname: Khan
authors.forename: M
authors.initials: M
authors.lastname: Osman
authors.lastname: Jumma-A-Jalal
authors.forename: M A
authors.initials: MA
authors.lastname: Rouf
authors.forename: K M H S S
authors.initials: KM
authors.lastname: Haque
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood*; D001426:Bacterial Proteins; D001459:Bangladesh; D002648:Child; D002675:Child, Preschool; D003851:Deoxyribonucleases / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012423:Rural Health; D013297:Streptococcus pyogenes / Q000276:immunology*; D013301:Streptolysins / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D013301:Streptolysins; C025964:streptolysin O; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B