title: Treatment of benign biliary strictures in chronic pancreatitis by self-expandable metal stents.
abstract: OBJECTIVE
  To determine the efficacy the value of self-expandable metal stents in patients with benign biliary strictures caused by chronic pancreatitis.
  
  
  METHODS
  61 patients with symptomatic common bile duct strictures caused by alcoholic chronic pancreatitis were treated by interventional endoscopy.
  
  
  RESULTS
  Initial endoscopic drainage was successful in all cases, with complete resolution of obstructive jaundice. Of 45 patients who needed definitive therapy after a 12-months interval of interventional endoscopy, 12 patients were treated with repeated plastic stent insertion (19.7%) or by surgery (n = 30; 49.2%). In 3 patients a self-expandable metal stent was inserted into the common bile duct (4.9%). In patients treated with metal stents, no symptoms of biliary obstruction occurred during a mean follow-up period of 37 (range 18-53) months. The long-term success rate of treatment with metal stents was 100%.
  
  
  CONCLUSIONS
  Endoscopic drainage of biliary obstruction by self-expandable metal stents provides excellent long-term results. To identify patients who benefit most from self-expandable metal stent insertion, further, prospective randomized studies are necessary.
authors.affiliation: Department of Gastroenterology, Otto von Guericke University, Magdeburg, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Kahl
authors.forename: Sandra
authors.initials: S
authors.lastname: Zimmermann
authors.forename: Bernhard
authors.initials: B
authors.lastname: Glasbrenner
authors.forename: Matthias
authors.initials: M
authors.lastname: Pross
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Schulz
authors.forename: Deirdre
authors.initials: D
authors.lastname: McNamara
authors.forename: Peter
authors.initials: P
authors.lastname: Malfertheiner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001651:Cholestasis, Extrahepatic / Q000209:etiology / Q000628:therapy*; D002908:Chronic Disease; D003137:Common Bile Duct Diseases / Q000209:etiology / Q000628:therapy*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D019512:Pancreatitis, Alcoholic / Q000150:complications*; D015607:Stents
chemical_list: D008670:Metals