title: [Relationship between serum asymmetric dimethylarginine and blood pressure in patients with chronic renal failure].
abstract: OBJECTIVE
  To investigate the relationship between serum assymmetric dimethylarginine and blood pressure in patients with chronic renal failure.
  
  
  METHODS
  We examined the levels of asymmetric dimethylarginine (ADMA) in the serum and urine of 29 hemodialysis patients using the HPLC method, and assessed the relationship between serum ADMA and blood pressure.
  
  
  RESULTS
  The level of serum ADMA was higher, but the level of urinary ADMA was lower in the patients with chronic renal failure than those in the controls. The serum ADMA was positively related to blood pressure.
  
  
  CONCLUSIONS
  The accumulation of ADMA may be related to hypertension in patients with chronic renal failure.
authors.affiliation: Department of Nephrology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Wei-ru
authors.initials: WR
authors.lastname: Zhang
authors.forename: Li-jian
authors.initials: LJ
authors.lastname: Tao
authors.forename: Ben-mei
authors.initials: BM
authors.lastname: Chen
mesh_terms: D000328:Adult; D001120:Arginine / Q000031:analogs & derivatives* / Q000097:blood* / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications / Q000652:urine; D008297:Male; D008875:Middle Aged; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D006435:Renal Dialysis
chemical_list: C018524:N,N-dimethylarginine; D001120:Arginine; D019001:Nitric Oxide Synthase