Relationship between cord blood level of IgE specific for Dermatophagoides pteronyssinus and allergic manifestations in infancy.
The relationship between the cord blood level of IgE specific for Dermatophagoides pteronyssinus (Dp-IgE) and the development of allergic disorders in infants was investigated. None of the 10 infants who had no family history of allergic disorders and a cord blood Dp-IgE level of <0.07 IU/ml developed atopic dermatitis by 10 months of age. Among the infants whose mothers had atopy, those with a cord blood Dp-IgE level of > or =0.07 IU/ml showed a higher prevalence of allergic disorders at 3 years of age than those with a cord blood Dp-IgE level of <0.07 IU/ml. These observations suggest that the cord blood Dp-IgE level may be related to allergic manifestations in infancy.
Nambu
Mitsuhiko
M
Department of Pediatrics, Tenri Hospital, Tenri City, Nara-ken, Japan. mearin@kcn.ne.jp
Shintaku
Noriaki
N
Ohta
Shigeru
S
D017677:Age Distribution; D000375:Aging / Q000276:immunology; D003876:Dermatitis, Atopic / Q000453:epidemiology; D040002:Dermatophagoides pteronyssinus / Q000276:immunology*; D005260:Female; D005312:Fetal Blood; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000235:genetics; D007073:Immunoglobulin E / Q000032:analysis* / Q000276:immunology*; D015994:Incidence; D008499:Medical Records; D011247:Pregnancy; D015995:Prevalence
D007073:Immunoglobulin E