Cell adhesion: a FERM grasp of membrane dynamics.
Two recent papers provide the first evidence for a common mechanism of targeting and activation of an enzyme that is important in the rapid regulation of both focal adhesion assembly during cell migration and synaptic vesicle recycling at nerve terminals.
Liddington
Robert C
RC
Program on Cell Adhesion, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. rlidding@burnham.org
Bankston
Laurie A
LA
de Pereda
Jose M
JM
D000595:Amino Acid Sequence; D002448:Cell Adhesion / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism*; D008958:Models, Molecular; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000235:genetics / Q000378:metabolism; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D016608:Talin / Q000235:genetics / Q000378:metabolism
D016608:Talin; D017853:Phosphotransferases (Alcohol Group Acceptor)