title: Asymptomatic microbleeds as a risk factor for aspirin-associated intracerebral hemorrhages.
abstract: The authors measured the presence and extent of asymptomatic microbleeds on gradient-recalled-echo MRI in 21 aspirin users who developed intracerebral hemorrhage and 21 aspirin users without history of intracerebral hemorrhage. Microbleeds were more frequent (19 vs 7, p < 0.001) and more extensive (mean number of microbleeds 13.3 vs 0.4, p < 0.001) in the intracerebral hemorrhage group than in the control group. Asymptomatic microbleeds may be a risk factor for aspirin-associated intracerebral hemorrhage.
authors.affiliation: Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin. ks-wong@cuhk.edu.hk
authors.forename: K S
authors.initials: KS
authors.lastname: Wong
authors.forename: Y L
authors.initials: YL
authors.lastname: Chan
authors.forename: J Y
authors.initials: JY
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Gao
authors.forename: W W M
authors.initials: WW
authors.lastname: Lam
mesh_terms: D000368:Aged; D001241:Aspirin / Q000009:adverse effects*; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis* / Q000453:epidemiology; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D018450:Disease Progression; D005260:Female; D006485:Hemosiderin / Q000032:analysis; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015588:Observer Variation; D011237:Predictive Value of Tests; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D016861:Cyclooxygenase Inhibitors; D006485:Hemosiderin; D001241:Aspirin