title: Efficacy of contained metaphyseal and periarticular defects treated with two different demineralized bone matrix allografts.
abstract: The efficacies of two different allografts, Grafton (demineralized bone matrix [DBM] in a glycerol carrier) and Orthoblast (DBM in a reverse thermal poloxamer carrier) were examined from cases involving periarticular fractures. Demographic, perioperative, and outcome data for patients with periarticular fractures who underwent a prospectively designed protocol for bone grafting were compiled, with 15 cases using Orthoblast and 13 using Grafton. A successful graft was defined as healing on the first graft attempt without complications. Healing was determined by radiographic studies and clinical evaluation. The successful graft rates of Orthoblast and Grafton were 15/15 and 9/13, respectively.
authors.affiliation: University of Pittsburgh Medical Center, Department of Orthopaedic Surgery, Suite 1010 Kaufmann Bldg., 3471 Fifth Ave., Pittsburgh, PA 15213, USA.
authors.forename: S
authors.initials: S
authors.lastname: Cheung
authors.forename: K
authors.initials: K
authors.lastname: Westerheide
authors.forename: B
authors.initials: B
authors.lastname: Ziran
mesh_terms: D000328:Adult; D000368:Aged; D018775:Bone Demineralization Technique; D001857:Bone Matrix; D016025:Bone Transplantation / Q000379:methods*; D015331:Cohort Studies; D004838:Epiphyses; D005260:Female; D005500:Follow-Up Studies; D017102:Fracture Healing / Q000502:physiology; D050723:Fractures, Bone / Q000175:diagnosis / Q000601:surgery*; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D015601:Injury Severity Score; D007596:Joints / Q000293:injuries / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D011336:Probability; D011446:Prospective Studies; D014184:Transplantation, Homologous; D016896:Treatment Outcome