title: A general frame of theory on genetic load.
abstract: Genetic load expresses the loss in mean fitness of a population because of the genetic variability present. The quantitative discussion of various genetic loads is provided with important meaning for research into evolution of species on realistic level. The past theory on genetic load starts off with equilibrium of population to investigate the evolution of species on realistic level. However, the evolution is a displacement on equilibrium of population. This is just made up of a contradiction between theory and praxis. We branch out the past theory on genetic load, and give out a general theoretic frame describing the various genetic loads. By the use of this theoretic frame the genetic loads in an equilibrium population can be represented, and the genetic loads in a non-equilibrium population and their change can also be simulated. Thus this theoretic frame overcomes the shortcoming of past theory on genetic loads, which can't describe non-equilibrium population and conflicts with praxis of biological evolution sometimes, and offers a sort of credible simulation methods for research into evolution of species.
authors.affiliation: Hubei Agricultural College, Jingzhou 434103, China.
authors.forename: Guo-Kai
authors.initials: GK
authors.lastname: Wu
mesh_terms: D040741:Genetic Load; D015810:Linkage Disequilibrium; D008957:Models, Genetic; D012641:Selection, Genetic