[Clinical and experimental study on effect of jietongyin lotion in treating vulvovaginitis in young girls].
OBJECTIVE
To study the clinical effect and mechanism of Jietongyin Lotion (JTYL) in treating vulvovaginitis in young girls.


METHODS
Patients were randomized into the JTYL group (n = 300) and the control group (n = 60, treated with Rishu an Lotion). Comparative observation on scoring of main symptoms and signs in them was carried out, and the pharmacological and pharmacodynamic experiment was also conducted on effect of JTYL in animals.


RESULTS
In the JTYL group, the total effective rate was 98% and was 93% in the control group. The cure rate in the two groups was 93% and 83% respectively, which was significantly higher in the JTYL group (P < 0.05). Experimental study showed that JTYL has effects in anti-inflammation, bacteriocidal, itching relieving, pain releasing, and immune regulation. It showed non-irritatory on mucous membrane.


CONCLUSIONS
JTYL has good reliable effect in treating vulvovaginitis in young girls without any obvious adverse effects, showing anti-inflammatory, bacteriocidal, itching relieving, pain releasing and immune regulation.
Liu
Hui-li
HL
Affiliated Children Hospital, Capital University of Medical Sciences, Beijing 100045.
Liu
Jing
J
Chen
Zhao-ding
ZD
D000287:Administration, Topical; D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000494:pharmacology; D001494:Baths; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007223:Infant; D008297:Male; D051379:Mice; D008517:Phytotherapy; D011817:Rabbits; D011897:Random Allocation; D014848:Vulvovaginitis / Q000188:drug therapy*
D000890:Anti-Infective Agents; D004365:Drugs, Chinese Herbal