JU-2, a novel phosphorous-containing antifungal antibiotic from Streptomyces kanamyceticus M8.
A novel phosphorous-containing antifungal antibiotic JU-2 was isolated from Streptomyces kanamyceticus M8. Quantitative chemical analysis shows the presence of two phenylalanines, two glucose, one linoleic acid, one crucic acid and one phosphonamide moiety per molcule of the antibiotic. JU-2 shows strong inhibitory activity against various pathogenic and non-pathogenic fungi but no activity against bacteria and yeast.
Datta
I
I
Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta 700 032, India.
Banerjee
M
M
Mukherjee
S K
SK
Majumdar
S K
SK
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013302:Streptomyces / Q000737:chemistry*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; C471888:JU2 antibiotic