title: Unusual herpes simplex virus infection mimicking foreign body reaction after cosmetic lip augmentation with expanded polytetrafluoroethylene threads.
abstract: BACKGROUND
  Adverse reactions after cosmetic lip augmentation with synthetic implant materials include inflammation, infection, and extrusion of and foreign body reaction to the implant. Clinically, all of them are characterized by pain, erythema, swelling, and formation of papules and/or pustules.
  
  
  OBJECTIVE
  To describe an unusual herpes simplex virus infection in a 48-year-old female patient after cosmetic lip augmentation with expanded polytetrafluoroethylene threads clinically resembling a foreign body reaction.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  A histopathologic examination showed no signs of a foreign body reaction. Instead, herpes simplex virus-specific DNA was demonstrated by polymerase chain reaction from lesional tissue.
  
  
  CONCLUSIONS
  Cosmetic lip augmentation with expanded polytetrafluoroethylene threads may be complicated by a delayed local herpes simplex virus infection clinically mimicking a foreign body reaction to the implant.
authors.affiliation: Department of Dermatology, Karl-Franzens-University School of Medicine, Graz, Austria. christina.rudolph@kfunigraz.ac.at
authors.forename: Christina M
authors.initials: CM
authors.lastname: Rudolph
authors.forename: Robert R
authors.initials: RR
authors.lastname: Müllegger
authors.forename: Sanja
authors.initials: S
authors.lastname: Schuller-Petrovic
authors.forename: Helmut
authors.initials: H
authors.lastname: Kerl
authors.forename: H Peter
authors.initials: HP
authors.lastname: Soyer
mesh_terms: D005260:Female; D005549:Foreign-Body Reaction / Q000175:diagnosis*; D006561:Herpes Simplex / Q000175:diagnosis*; D006801:Humans; D008046:Lip / Q000601:surgery / Q000821:virology; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants / Q000009:adverse effects*; D019651:Plastic Surgery Procedures; D018139:Simplexvirus / Q000502:physiology*; D013997:Time Factors; D014775:Virus Activation
chemical_list: D011138:Polytetrafluoroethylene