[Studies on immunocompetent constituents of Patrinia scabra Bunge].
Five compounds were isolated from the roots of Patrinia scabra Bunge separated and purified on sillica gel column chromatography. Their structures were elucidated on the physico-chemical properties and spectral data as lariciresinol(I), syringaresinol(II), scopoletin(III), quercetin(IV), ferulaic acid(V). All compounds were obtained from P. scabra for the first time. In vitro biological test of these compounds showed that syringaresinol was able to stimulate T and B lymphocyte proliferation.
Gu
Zhengbing
Z
College of Pharmacy, Second Military Medical University, Shanghai 200433.
Chen
Xinjian
X
Yang
Genjin
G
Li
Tingzhao
T
Liu
Wenyong
W
Zhang
Weidong
W
D001402:B-Lymphocytes / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D032405:Patrinia / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012603:Scopoletin / Q000737:chemistry / Q000302:isolation & purification; D013601:T-Lymphocytes / Q000187:drug effects
D004365:Drugs, Chinese Herbal; D005663:Furans; D017705:Lignans; C042192:syringaresinol; C060282:lariciresinol; D012603:Scopoletin