Effect of 0.2% brimonidine on retinal blood flow.
OBJECTIVE
To analyze the effect of 0.2% brimonidine eye drops on retinal blood flow of patients with glaucoma.


METHODS
Using self-control method and Heidelberg Retina Flowmeter (HRF), we examined the volume, flow and velocity of the superior nasal and temporal, the inferior nasal and temporal artery of retina at baseline and 2 hours after single instillation of 0.2% brimonidine.


RESULTS
There were no significant changes in volume, flow and velocity of four vessels before and after the administration of 0.2% brimonidine.


CONCLUSIONS
There are no significant ocular haemodynamic benefits associated with Brimonidine therapy to the glaucoma patients.
Yu
M
M
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Li
Y
Y
Liu
X
X
Ling
Y
Y
Zheng
X
X
D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000068438:Brimonidine Tartrate; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009883:Ophthalmic Solutions; D011810:Quinoxalines / Q000008:administration & dosage / Q000627:therapeutic use*; D012039:Regional Blood Flow / Q000187:drug effects; D012171:Retinal Vessels / Q000503:physiopathology*
D000316:Adrenergic alpha-Agonists; D009883:Ophthalmic Solutions; D011810:Quinoxalines; D000068438:Brimonidine Tartrate