title: Disabling overactivity of the extensor hallucis longus after stroke: clinical expression and efficacy of botulinum toxin type A.
abstract: OBJECTIVE
  To describe the clinical characteristics of persistent extension of the great toe related to overactivity of the extensor hallucis longus (EHL) after a stroke and to explore the efficacy of treatment with botulinum toxin type A.
  
  
  METHODS
  Case series.
  
  
  METHODS
  A physical medicine and rehabilitation department in France.
  
  
  METHODS
  Eleven patients with hemiplegia disabled by overactivity of the EHL were classified according to the different ways in which that overactivity was triggered. Disability was related to pain in 5 patients, to shoe difficulties in 10 patients, and to varus foot in 6 patients.
  
  
  METHODS
  Injection of botulinum toxin type A into the EHL.
  
  
  METHODS
  Efficacy was assessed on day 15 by triggering of pain, shoe difficulties, and varus deformity and by patients' subjective assessment on day 15, at 3 months, and at 6 months.
  
  
  RESULTS
  On day 15, EHL overactivity disappeared after 16 of the 18 injections in 10 patients; subjective assessment was very good for pain and shoe difficulties and remained good or very good at 3 months for 8 patients who received 12 injections.
  
  
  CONCLUSIONS
  Botulinum toxin type A is effective in treating disability related to poststroke overactivity of the EHL.
authors.affiliation: Physical Medicine and Rehabilitation Department, GH Lariboisière-Fernand Widal, Paris, France. alain.yelnik@lrb.ap-hop-paris.fr
authors.forename: Alain P
authors.initials: AP
authors.lastname: Yelnik
authors.forename: Florence M
authors.initials: FM
authors.lastname: Colle
authors.forename: Isabelle V
authors.initials: IV
authors.lastname: Bonan
authors.forename: Delphine R
authors.initials: DR
authors.lastname: Lamotte
mesh_terms: D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D020821:Dystonic Disorders / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D000071939:Stroke Rehabilitation; D014034:Toes / Q000503:physiopathology*
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A