title: Dysgerminoma in a patient with a tumor of the neck. Empiric treatment of stage IV dysgerminoma.
abstract: The evolution of therapy for malignant ovarian germ cell tumors is one of the true success stories in oncology. Treatment outcome has improved greatly thanks to cisplatin-based combination chemotherapy. According to the well-established treatment guidelines for advanced cases, we treated a case of stage IV undifferentiated germ cell tumor in which we were able to preserve the patient's fertility. We concluded that the PEP regimen is an effective treatment for the patient with metastatic germ cell tumor.
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Medical University Hospital, Tokyo, Japan. saka@tokyo-med.ac.jp
authors.forename: Keiichi
authors.initials: K
authors.lastname: Isaka
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Akaeda
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Itoh
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hori
authors.forename: Tamaki
authors.initials: T
authors.lastname: Yudate
authors.forename: Junko
authors.initials: J
authors.lastname: Nagata
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Masaomi
authors.initials: M
authors.lastname: Takayama
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy*; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009367:Neoplasm Staging; D017663:Peplomycin / Q000008:administration & dosage; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed
chemical_list: D017663:Peplomycin; D005047:Etoposide; D002945:Cisplatin