[Effects of modified SD therapy on Bell's palsy].
OBJECTIVE
To investigate the effects of a modified SD therapy (intravenous high dose hydrocortisone and low molecular dextran) on Bell's palsy(BP), and to avoid the severe side-effects such as hepatic and renal disorders during the treatment.


METHODS
Seventy-one BP patients were treated with modified SD method (modified group), thirty-two BP patients took prednisone (control group), and the curative rates of two therapies were compared, in the meanwhile recorded the side effects in detail.


RESULTS
Curative rate in modified group was 95.8% (House-Brakmsnn I-II) and in control group was 81.2% (P < 0.05). In modified group, the curative rate (I grade) in the patients were treated within 24 hours following onset was 75.0%, and the curative rate in other three subgroups were treated within 24-48 hours, 2-3 day and 3-5 day following onset was 43.8%, 26.7%, 18.8% respectively. Modified group had not shown hepatic and renal disorders or gastric ulcer.


CONCLUSIONS
Modified SD method may increase recoverable rate and can avoid significant side effects for BP, and emphasizes the importance of the administration of SD therapy in the early stage of the disease.
Tian
J F
JF
Department of Otorhinolaryngology, 304th Hospital of People's Liberation Army, Beijing 100037.
Li
B X
BX
Liu
D G
DG
Zhou
C Y
CY
Wang
L L
LL
Han
H
H
D000328:Adult; D000368:Aged; D003911:Dextrans / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005158:Facial Paralysis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged
D003911:Dextrans; D006854:Hydrocortisone