Chemical constituents from the Hydrangea chinensis.
Two quinazolone alkaloids, (+)-febrifugine (1) and isofebrifugine (2), along with three coumarin derivatives, 6-hydroxy coumarin (3), skimmin (5), and umbelliferone-7-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranoside (6), were isolated from the roots of Hydrangea chinensis. Compound 6 is a new compound. In addition, umbelliferone (4), linoleic acid (7), two steroidal glycosides (8, 9), three furfural derivatives (10-12), and butyl-beta-D-fructofuranoside (13) were isolated from the leaves of the same plant. The structures of all isolates were elucidated by spectral methods.
Khalil
Ashraf Taha
AT
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chang
Fang-Rong
FR
Lee
Yue-Han
YH
Chen
Chung-Yi
CY
Liaw
Chih-Chuang
CC
Ramesh
Patnam
P
Yuan
Shyng-Shiou F
SS
Wu
Yang-Chang
YC
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D031966:Hydrangea / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D011799:Quinazolines / Q000737:chemistry / Q000302:isolation & purification
D003374:Coumarins; D010936:Plant Extracts; D011799:Quinazolines; C030123:coumarin