title: Analysis of dietary supplements for arsenic, cadmium, mercury, and lead using inductively coupled plasma mass spectrometry.
abstract: The arsenic, cadmium, mercury, and lead contents of 95 dietary supplement products were determined using microwave digestion and high-resolution inductively coupled plasma mass spectrometry. Precision and accuracy were demonstrated by element recovery from 17 dietary supplements and replicates of 8 reference materials. The concentration ranges were as follows: arsenic, <5-3770 microg/kg; cadmium, <10-368 microg/kg; mercury, <80-16800 microg/kg; and lead, <20-48600 microg/kg. An assessment of estimated exposures/intakes of the four elements is presented.
authors.affiliation: Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5100 Paint Branch Parkway, College Park, Maryland 20740-3835, USA.
authors.forename: Scott P
authors.initials: SP
authors.lastname: Dolan
authors.forename: David A
authors.initials: DA
authors.lastname: Nortrup
authors.forename: P Michael
authors.initials: PM
authors.lastname: Bolger
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Capar
mesh_terms: D001151:Arsenic / Q000032:analysis*; D002104:Cadmium / Q000032:analysis*; D019587:Dietary Supplements / Q000032:analysis*; D007854:Lead / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*; D008452:Maximum Allowable Concentration; D008628:Mercury / Q000032:analysis*; D011786:Quality Control; D012680:Sensitivity and Specificity
chemical_list: D002104:Cadmium; D007854:Lead; D008628:Mercury; D001151:Arsenic