[Study on erzhi pill effects on neuro-endocrinologic-immuno network of animal of deficiency of yin].
OBJECTIVE
To investigate Erzhi Pill effect on Neuro-Endocrinologic-Immuno network of animal of deficiency of Yin.


METHODS
In the experiment through the determination of hemotic cortisol, insulin, testosterone, beta-endorphin, cholesterol, weight of adrenal and thymus, ConA-induced, spleelymphocyte proliferation and activity of natural killer cells (NKC). The changes of the animals of deficiency of Yin and the effects of the Erzhi Pill were investigated.


RESULTS
It showed that rats of deficiency of Yin, their hemotic, cortisol, insulin, testosterone, beta-endorphin, weight of adrenal and thymus decreased, cholesterol increased and mouse of deficiency of Yin, their lymphocyte proliferation and activity of NKC dcreased, which might be modulated with Erzhi Pill. Erzhi Pill could improve hemotic cortisol, insulin, testosterone, beta-endorphin, weight of adrenal and thymus, reduce hemotic cholesterol, improve lymphocyte proliferation and activity of NKC.


CONCLUSIONS
This principle could improve animals of deficiency of Yin regulating Neuro-Endocrinologic-Immuno network and keeping homeostais.
Cao
H
H
Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405.
Liang
S
S
Rong
X
X
Wu
Q
Q
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D036601:Eclipta / Q000737:chemistry*; D007694:Killer Cells, Natural / Q000276:immunology*; D031659:Ligustrum / Q000737:chemistry*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D016710:Yin Deficiency / Q000276:immunology / Q000378:metabolism*; D001615:beta-Endorphin / Q000097:blood
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C477278:erzhi pill; D001615:beta-Endorphin