title: Eyelid tremor in a patient with a unilateral paramedian thalamic lesion.
abstract: A patient with a circumscribed infarction of the right paramedian thalamus developed a tremor of both eyelids on voluntary eye closure. Co-registration of the magnetic resonance image to a stereotactic atlas of the human thalamus revealed that the lesion was confined to a small subgroup of paramedian nuclei, including the parvocellular part of the mediodorsal nucleus. It is concluded that this region provides inhibitory input to cortical and/or subcortical regions controlling eyelid movements. Voluntary eye closure may involve direct cortico-nuclear connections and indirect pathways through the paramedian thalamus, most probably through the mediodorsal nucleus.
authors.affiliation: Klinik für Neurologie, Charité, Humboldt-Universität, Berlin, Germany. jan.junge-huelsing@charite.de
authors.forename: G J
authors.initials: GJ
authors.lastname: Jungehülsing
authors.forename: C J
authors.initials: CJ
authors.lastname: Ploner
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000150:complications* / Q000473:pathology*; D003937:Diagnosis, Differential; D004576:Electromyography / Q000379:methods; D004585:Electrooculography; D005143:Eyelids / Q000503:physiopathology*; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013788:Thalamus / Q000098:blood supply* / Q000473:pathology*; D014202:Tremor / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*