A new coumestan from Tephrosia calophylla.
A new coumestan, tephcalostan (1) has been isolated from the whole plant of Tephrosia calophylla BEDD. together with two known flavonoids, 7-O-methylglabranin (2) and kaempferol 3-O-beta-D-glucopyranoside (3). The structure of tephcalostan was elucidated as 5'-(R)-8, 9-methylenedioxy-5'-isopropenyl-4', 5'-dihydrofurano[2', 3':2, 3]coumestan by extensive one-and two-dimensional (1D- and 2D-)-NMR techniques including (1)H-(1)H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and nuclear Overhauser enhancement spectroscopy (NOESY) experiments.
Hari Kishore
Pennaka
P
Natural Products Division, Department of Chemistry, Sri Venkateswara University, Paris, France.
Vijaya Bhaskar Reddy
Mopuru
M
Gunasekar
Duvvuru
D
Marthanda Murthy
Madugula
M
Caux
Cristelle
C
Bodo
Bernard
B
D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018514:Plant Structures; D031304:Tephrosia
D003374:Coumarins; D005419:Flavonoids; D010936:Plant Extracts