title: Tool command language automation of the modular ion cyclotron data acquisition system (MIDAS) for data-dependent tandem Fourier transform ion cyclotron resonance mass spectrometry.
abstract: This manuscript describes the addition of data-dependent automation to the modular ion cyclotron resonance data acquisition system (MIDAS). The automation is made possible by developments and incorporation of a tool command language (Tcl) interpreter for automated acquisition. To accomplish the automation, real-time generation of excitation waveforms and scriptable data post-processing has been implemented into the MIDAS source code. In addition a new excitation event has also been added to allow for run-time generation of a single notch stored waveform inverse Fourier transform (SWIFT) excitation event. Examples of these new features and discussion of their enhancement to the existing data station are presented.
authors.affiliation: Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA. freitas@chemistry.ohio-state.edu
authors.forename: Michael A
authors.initials: MA
authors.lastname: Freitas
authors.forename: Eric
authors.initials: E
authors.lastname: King
authors.forename: Stone D-H
authors.initials: SD
authors.lastname: Shi
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000737:chemistry; D000809:Angiotensins / Q000737:chemistry; D000818:Animals; D001331:Automation / Q000379:methods; D002417:Cattle; D017357:Cyclotrons / Q000295:instrumentation*; D005583:Fourier Analysis; D007256:Information Systems / Q000295:instrumentation; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D012984:Software; D025801:Ubiquitin / Q000737:chemistry
chemical_list: D000809:Angiotensins; D025801:Ubiquitin; D000324:Adrenocorticotropic Hormone