title: Conservative management of cervical intraepithelial neoplasia (CIN(2-3)) in pregnant women.
abstract: The management of cervical intraepithelial neoplasia (CIN(2-3)) diagnosed during pregnancy was the subject of this study. Two hundred and eight pregnant women with an abnormal cytology were assessed in our unit over a 10-year period. The age of the patients ranged from 20 to 45 (mean 28) years. Seventy-eight of these women were histologically proven to have CIN(2-3). All patients were followed up every 8-10 weeks by cytology and colposcopy during pregnancy and reassessed 8-12 weeks postpartum. The disease persisted in 30 cases (38.4%), whereas in the remaining 48 cases it regressed to CIN(1). No case of invasive disease developed during the follow-up period in these pregnant patients. Conservative management of CIN(2-3) during pregnancy is acceptable, but close follow-up and colposcopic expertise are necessary.
authors.affiliation: Gynecologic Oncology and Colposcopy Units, 1st Department of Obstetrics and Gynecology, Alexandra Hospital, Athens University, Athens, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Vlahos
authors.forename: A
authors.initials: A
authors.lastname: Rodolakis
authors.forename: E
authors.initials: E
authors.lastname: Diakomanolis
authors.forename: K
authors.initials: K
authors.lastname: Stefanidis
authors.forename: D
authors.initials: D
authors.lastname: Haidopoulos
authors.forename: K
authors.initials: K
authors.lastname: Abela
authors.forename: V
authors.initials: V
authors.lastname: Georgountzos
authors.forename: S
authors.initials: S
authors.lastname: Michalas
mesh_terms: D000328:Adult; D003127:Colposcopy; D005260:Female; D005500:Follow-Up Studies; D006115:Greece / Q000453:epidemiology; D006801:Humans; D008499:Medical Records; D008875:Middle Aged; D009367:Neoplasm Staging; D049590:Postpartum Period; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*