title: Scleroderma, stroke, optic neuropathy: a rare association.
abstract: A known case of scleroderma presented with right hemiparesis, focal seizures, optic atrophy and gangrene of digits. There was no evidence of peripheral nerve or muscle involvement. MRI showed multifocal infarcts in both cerebral hemispheres. MR angiography revealed poor flow in bilateral carotid arteries with collateralization from posterior circulation. She improved with phenytoin, nifedipine, antibiotics and immunosuppressants. The rarity of central nervous system affliction in scleroderma and large vessel vasculitis is discussed along with review of literature.
authors.affiliation: Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India. dascp@glide.net.in
authors.forename: C P
authors.initials: CP
authors.lastname: Das
authors.forename: S
authors.initials: S
authors.lastname: Prabhakar
authors.forename: V
authors.initials: V
authors.lastname: Lal
authors.forename: P S
authors.initials: PS
authors.lastname: Kharbanda
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009896:Optic Atrophy / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000150:complications*; D020521:Stroke / Q000209:etiology*