title: Carcinosarcoma of the stomach.
abstract: In the gastrointestinal tract, carcinosarcomas are most frequently seen in the esophagus. Carcinosarcoma in the stomach is a rare tumor. We report a carcinosarcoma of the antrum of stomach. The tumor was polypoid and exophytic in appearance and located in the antrum. Immunohistochemical studies showed positivity for cytokeratin, epithelial membrane antigen and cytoplasmic carcinoembryonic antigen in the epithelial component. Positive staining with vimentin, desmin and focal smooth muscle actin and negative staining with chromogranin were observed in spindle cells. Nuclear positive staining was observed with p53 and Ki-67 in both glandular and spindle atypical cells.
authors.affiliation: Department of Pathology, Baskent University Faculty of Medicine, Yüregir, Adana, 01250, Turkey. faziletks@yahoo.com
authors.forename: Fazilet
authors.initials: F
authors.lastname: Kayaselcuk
authors.forename: Ilhan
authors.initials: I
authors.lastname: Tuncer
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Toyganözü
authors.forename: Nebil
authors.initials: N
authors.lastname: Bal
authors.forename: Gürsel
authors.initials: G
authors.lastname: Ozgür
mesh_terms: D002296:Carcinosarcoma / Q000473:pathology* / Q000601:surgery*; D003893:Desmin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012509:Sarcoma / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*; D013276:Stomach Ulcer / Q000473:pathology / Q000601:surgery
chemical_list: D003893:Desmin