Babesiosis: persistence in the face of adversity.
Many babesial parasites establish infections of long duration in immune hosts. Among different species, at least four mechanisms are known that could facilitate evasion of the host immune response, although no one species is (yet) known to use them all. This update strives to illustrate the ramifications of these mechanisms and the interplay between them.
Allred
David R
DR
Dept of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611-0880, USA. allredd@mail.vetmed.ufl.edu
D000818:Animals; D000940:Antigenic Variation / Q000276:immunology; D001403:Babesia / Q000276:immunology / Q000472:pathogenicity* / Q000502:physiology; D001404:Babesiosis / Q000453:epidemiology / Q000276:immunology*; D002448:Cell Adhesion / Q000276:immunology; D004198:Disease Susceptibility / Q000662:veterinary; D004912:Erythrocytes / Q000378:metabolism / Q000469:parasitology; D005786:Gene Expression Regulation; D006790:Host-Parasite Interactions; D005810:Multigene Family / Q000235:genetics