title: [A method to identify BSE suspects in emergency slaughtered cattle during ante mortem examination].
abstract: A method is presented by which a maximal number of BSE-infected cattle that had escaped the filter of clinical examination are identified during ante mortem examination. This approach might prove to be an efficient and cost-effective method for veterinary and non-veterinary meat inspectors to remove infected animals prior to slaughter. In a case-control study, the clinical signs of 224 randomly selected sick slaughtered animals were compared with the clinical signs of 26 sick slaughtered animals in which BSE infection was diagnosed using a rapid test post mortem. In addition, the clinical signs of the sick slaughtered BSE-positive animals were compared with the clinical signs of a group of BSE suspects identified during the same time period and in which BSE infection could be confirmed. As a result of this study a mathematical model was developed to identify BSE suspects. This model contains a total of 7 variables (clinical signs) that proved to be of importance. These signs were aggressive behaviour, grinding of teeth, protruding eyeballs, reduced rumination, inability to stand, overexcitability, and difficulty in standing up. The presented model has a sensitivity of 61.5% (16 out of 26 BSE-positive animals slaughtered while sick were identified) and a specificity of 99.6% when compared to a rapid test conducted post mortem.
authors.affiliation: Bundesamt für Veterinärwesen, Bern-Liebefeld.
authors.forename: A R
authors.initials: AR
authors.lastname: Hett
authors.forename: J
authors.initials: J
authors.lastname: Rüfenacht
authors.forename: L
authors.initials: L
authors.lastname: Perler
authors.forename: D
authors.initials: D
authors.lastname: Heim
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D016022:Case-Control Studies; D002417:Cattle; D016643:Encephalopathy, Bovine Spongiform / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D008124:Locomotion; D008297:Male; D008962:Models, Theoretical; D010808:Physical Examination / Q000662:veterinary; D012680:Sensitivity and Specificity