[Immunochemical demonstration of human herpes virus 8 in conjunctival Kaposi's sarcoma].
BACKGROUND
Angiomatous lesions of the conjunctiva and chronic conjunctivitis are frequently difficult to differentiate.


METHODS
A 28 year old white male sought help because of a conjunctival swelling. A biopsy made elsewhere had revealed a capillary haemangioma of the conjunctiva. Recently striking alterations of the skin led to the suspicion of a Kaposi's sarcoma. Immunohistochemical and dermatological examinations confirmed the diagnosis of a Kaposi's sarcoma and viral testing of serum revealed an HIV-infection. Besides intensive antiviral therapy, our patient underwent local irradiation of the right eye, the nose and of the left shoulder with an external beam.


CONCLUSIONS
Kaposi's sarcoma is the most frequent Aids-associated malignant tumor. In about 30% of all patients with Aids, a Kaposi's sarcoma is diagnosed. The angiomatous character may lead to the histopathological diagnosis of a haemangioma. Human herpes virus 8 is known to be the transforming element.
Hasche
H
H
Augenklinik der Julius-Maximilians-Universität Würzburg.
Eck
M
M
Lieb
W
W
D000386:AIDS-Related Complex; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001706:Biopsy; D003230:Conjunctival Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D005500:Follow-Up Studies; D018324:Hemangioma, Capillary / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D019288:Herpesvirus 8, Human; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010315:Particle Accelerators; D011879:Radiotherapy Dosage; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D013997:Time Factors