[Cycloartane triterpenes and glycosides from Cimicifuga acerina].
OBJECTIVE
To investigate the chemical constituents from the rhizomes of Cimicifuga acerina (Sieb. et Zucc.) Tanaka.


METHODS
Column chromatgraphy (including silica gel and ODS) together with HPLC was used to separate the chemical constituents whose structures were determined by FAB-MS, NMR (1D and 2D) and hydrolysis methods.


RESULTS
Five cycloartane triterpenoids were isolated and identified as: (22R)-22-hydroxycimigenol (I), (22R)-22-hydroxy-24-O-acetylhydroshengmanol 3-O-beta-D-xylopyranoside (II), dahurinol (III), 24-epi-24-O-acetyl-7,8-didehydroshengmanol 3-O-beta-D-xylopyranoside (IV), 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside (V).


CONCLUSIONS
Compound I is a new natural product, compound II is a new compound and compounds IV and V were isolated from this plant for the first time.
Zhang
Q W
QW
Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.
Ye
W C
WC
Che
C T
CT
Zhao
S X
SX
D031885:Cimicifuga / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification
C475453:22-hydroxy-24-O-acetylhydroshengmanol 3-O-xylopyranoside; C475454:22-hydroxycimigenol; D012503:Saponins; D014315:Triterpenes