title: [The Feature of Skewing Distribution of TCR Vbeta T Cells from Peripheral Blood and Bone Marrow in Patients with AML-M(5)]
abstract: The TCR Vbeta 24 subfamily genes were amplified in peripheral blood and bone marrow mononuclear cells from 5 cases with acute monocytic leukemia (AML-M(5)) using RT-PCR, to observe the distribution of TCR Vbeta subfamilies. The results indicated that 1 - 19 Vbeta subfamily T cells could be identified in different samples from AML-M(5) cases. The variation of distribution of TCR Vbeta subfamily T cells could be found in different individual samples. The results provided the feature of cell immune function change in skewed distribution of TCR Vbeta subfamily T cells from peripheral blood and bone marrow of patients with AML-M(5).
authors.affiliation: Department of Hematology, Medical College, Jinan University, Guangzhou 510632, China; Deptartment of Hematology, The First Affiliated Hospitol of Medical College, Jinan University, Guangzhou 510632, China.
authors.forename: Lijian
authors.initials: L
authors.lastname: Yang
authors.forename: Yangqiu
authors.initials: Y
authors.lastname: Li
authors.forename: Shaohua
authors.initials: S
authors.lastname: Chen
authors.forename: Mingfang
authors.initials: M
authors.lastname: Qi
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Lu
authors.forename: Gengxin
authors.initials: G
authors.lastname: Luo