title: Pregnancy-associated Cushing's syndrome secondary to a luteinizing hormone/human chorionic gonadotropin receptor-positive adrenal carcinoma.
abstract: Cushing's syndrome occurring during pregnancy is frequently due to an adrenal neoplasm. Adrenal gland tumors occasionally respond to luteinizing hormone (LH) or human chorionic gonadotropin (hCG). We report a case of Cushing's syndrome during and following pregnancy due to an adrenal carcinoma which expressed the LH/hCG receptor. The presence of these receptors may have led to the growth and function of the tumor during pregnancy.
authors.affiliation: Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794-8154, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Wy
authors.forename: H E
authors.initials: HE
authors.lastname: Carlson
authors.forename: P
authors.initials: P
authors.lastname: Kane
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: Z M
authors.initials: ZM
authors.lastname: Lei
authors.forename: C V
authors.initials: CV
authors.lastname: Rao
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000737:chemistry / Q000150:complications*; D000328:Adult; D002277:Carcinoma / Q000737:chemistry / Q000150:complications*; D003480:Cushing Syndrome / Q000209:etiology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D012333:RNA, Messenger / Q000032:analysis; D011974:Receptors, LH / Q000032:analysis* / Q000235:genetics
chemical_list: D012333:RNA, Messenger; D011974:Receptors, LH