[Chemical constituents of the essential oil from the fruits of Lindera glauca and its antifungal activities].
The chemical constituents of the two essential oils extracted from the fruits of Lindera glauca by hydrodistillation and petroleum ether have been studied by means of GC-MS. Among which, 32 kinds of constituents were identified in distilling oil and 22 kinds in solvent oil. The main components in distilling oil were n-carpric acid (25.39%), germacrene A (10.71%), n-dodecanole acid (10.08%), epishyobunol acetate (7.29%) and caryophyllene oxide (5.44%), and in solvent oil were camphene (17.55%), 3,6,6-trimethyl-2-norpinene (16.85%), capric acid, ethyl ester (13.61%), eucalyptol (8.10%), and alpha-cis-ocimene (7.38%), In vitro the distilling oil exhibited more manifest antifungal properties than the solvent oil with MIC between 0.03-0.5 ml/L for pathogenic fungi species and 1.0-1.5 ml/L for moulds. Almost having not contained the sesquiterpenoids and their derivatives in the solvent oil maybe were a reason of poor inhibitory.
Yang
D
D
Zhongshan University, Guangzhou 510275.
Wang
F
F
Ren
S
S
Zhang
H
H
Peng
J
J
D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D000081008:Bicyclic Monoterpenes; D003455:Cryptococcus neoformans / Q000187:drug effects; D005638:Fruit / Q000737:chemistry; D027443:Lindera / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis; D045788:Sesquiterpenes, Germacrane; D013729:Terpenes / Q000032:analysis
D000935:Antifungal Agents; D000081008:Bicyclic Monoterpenes; D009822:Oils, Volatile; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; D013729:Terpenes; C471077:germacrene A; C019286:camphene