[Research on the mechanism of Yin-enriching and Qi-reinforcing, strengthening body and tonification deficiency syndrome action of radix Panacis quinquefolii].
Radix Panacis Quinquefolii could significantly promote 3H-TdR infiltrating of spontaneously and ConA-stimulated splenic lymphocytes of mice; Promote the splenic lymphocytes capacity of mice in interleukin2 (IL-2) production; Significantly enhance erythropoitin (EPO) level of mice in serum; Markedly promote production of colony stimulating factors (CSFs) in murine spleen-conditioned medium (SCM); And promote production of CSFs in lung-conditioned medium (LCM) of mice. The results suggest that yin-enriching and qi-reinforcing, strengthening body and tonification deficiency syndrome action of Radix Panacis Quinquefolii is in association with its lymphocytes activation-stimulating, IL-2 secrection-promoting, EPO secrection, and CSTs production enhancing effectes.
Gao
Y
Y
Fuzou Infectious Hospital, Fujian 350025.
Chen
Y
Y
Wang
B
B
D000818:Animals; D003115:Colony-Stimulating Factors / Q000096:biosynthesis*; D017077:Culture Media, Conditioned; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004921:Erythropoietin / Q000097:blood; D005260:Female; D007376:Interleukin-2 / Q000096:biosynthesis; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D005894:Panax / Q000737:chemistry*; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000378:metabolism
D003115:Colony-Stimulating Factors; D017077:Culture Media, Conditioned; D004365:Drugs, Chinese Herbal; D007376:Interleukin-2; D004921:Erythropoietin