[Supercritical-CO2 fluid extraction of fatty oils from Perilla frutescens seeds and pharmacological study].
Fatty oils from the seeds of Perilla frutescens were extracted by supercritical-CO2 fluid or petroleum ether and its quality was analyzed by GC-MS method. Pharmacological action of lowering blood-lipid for the oils was studied. The results showed that the technology of supercritical-CO2 extraction of the oils of P. frutescens seeds is superior than that of petroleum ether and the oil from SFE-CO2 have the action of lowering blood-lipid with low toxicity.
Tan
X
X
Guangzhou Pharmaceutical Industrial Research Institute, Guangzhou 510240.
Yie
L
L
Ge
F
F
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005227:Fatty Acids / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005638:Fruit / Q000737:chemistry; D006949:Hyperlipidemias / Q000188:drug therapy / Q000378:metabolism*; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000097:blood; D008297:Male; D051379:Mice; D031344:Perilla frutescens / Q000737:chemistry*; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011817:Rabbits; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods; D017962:alpha-Linolenic Acid / Q000302:isolation & purification
D004365:Drugs, Chinese Herbal; D005227:Fatty Acids; D000960:Hypolipidemic Agents; D008055:Lipids; D017962:alpha-Linolenic Acid