title: [Detection of Epstein-Barr virus DNA in fine needle aspiration specimen from cervical lymphnodes with polymerase chain reaction].
abstract: OBJECTIVE
  For the diagnosis of occult nasopharyngeal carcinoma.
  
  
  METHODS
  Epstein-Barr virus in 58 fine needle aspirations from cervical metastatic lymphnodes were detected with polymerase chain reaction.
  
  
  RESULTS
  The positive reaction was found in 28/35 metastatic carcinoma samples from middle or upside neck. Negative reaction was found in 3 lymphomas, 4 metastatic carcinomas in clavicular superior lymphnodes and 15/16 inflammatory diseases of cervical lymphnodes. The sensibility of this method for the diagnosis of nasopharyngeal carcinoma was 89.3%. The specificity was 86.7%.
  
  
  CONCLUSIONS
  The detection of Epstein-Barr virus in metastatic carcinoma from cervical lymphnodes had some clinical values for the diagnosis of occult nasopharyngeal carcinoma.
authors.affiliation: Department of Otolaryngology, Central Hospital of Jianghan Oil Field, Qianjiang, 433124.
authors.forename: Z X
authors.initials: ZX
authors.lastname: Lei
authors.forename: Q R
authors.initials: QR
authors.lastname: Liu
authors.forename: P
authors.initials: P
authors.lastname: Yuan
mesh_terms: D001707:Biopsy, Needle; D004279:DNA, Viral / Q000032:analysis*; D004854:Herpesvirus 4, Human / Q000235:genetics*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology* / Q000821:virology; D008207:Lymphatic Metastasis; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis*; D009333:Neck; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral