title: Dosimetric calculations and VIPAR polymer gel dosimetry close to the microSelectron HDR.
abstract: In the present study, different dosimetric methods were investigated for their ability to predict the energy dose in the vicinity of the microSelectron HDR 192Ir brachytherapy source. The results of a time-efficient Sievert integral model of proven accuracy in the cm distance range from all 192Ir sources were benchmarked against accurate Monte Carlo derived dosimetric data in the close vicinity of the source. This comparison revealed that the Sievert model is capable of accurate dosimetry even in the mm distance range from the source. The dose rate distributions were compared with results obtained from different versions (v. 13.7 and 14.2.2) of the Plato BPS commercial treatment planning system, for an application following the Paris trial intravascular irradiation protocol. The results of brachytherapy planning system calculations were found reliable at radial distances of clinical relevance. Noticeable errors existed only in the extreme case of dose calculations at 2 mm from the source axis using Plato v. 13.7. Experimental dosimetric data for the intravascular application, as obtained through the VIPAR polymer gel-MRI method, were also evaluated for dose verification purposes. This method allowed with reasonable accuracy the verification of absolute dose distributions for peripheral vessel applications using 192Ir sources.
authors.affiliation: Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71, Athens, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Kipouros
authors.forename: Georgios
authors.initials: G
authors.lastname: Anagnostopoulos
authors.forename: Angelos
authors.initials: A
authors.lastname: Angelopoulos
authors.forename: Dimos
authors.initials: D
authors.lastname: Baltas
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Baras
authors.forename: Anargiros
authors.initials: A
authors.lastname: Drolapas
authors.forename: Pantelis
authors.initials: P
authors.lastname: Karaiskos
authors.forename: Evangelos
authors.initials: E
authors.lastname: Pantelis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Papagiannis
authors.forename: Loukas
authors.initials: L
authors.lastname: Sakelliou
authors.forename: Ioannis
authors.initials: I
authors.lastname: Seimenis
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D005782:Gels; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007496:Iridium Radioisotopes / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*
chemical_list: D005782:Gels; D007496:Iridium Radioisotopes