[Study on effect of jinshui liujun jian oral liquid on serum superoxide dismutase activity and malonyldialdehyde content in mice with chronic bronchitis].
OBJECTIVE
To study the effect of Jinshui Liujun Jian Oral Liquid (JLJOL) on serum superoxide dismutase (SOD) activity and malonyldialdehyde (MDA) content in mice with chronic bronchitis.


METHODS
JLJOL was given to the chronic bronchitis mice model (induced by smoking) through gastrogavage, and then SOD activity and MDA content were tested.


RESULTS
SOD activity in model mice after JLJOL treatment was 0.67 +/- 0.15 NU/L, which was significantly higher than that in the untreated model (0.39 +/- 0.13 NU/L, P < 0.01). But the MDA content in treated mice was significantly lower than that in untreated one (9.26 +/- 2.90 nmol/L vs 16.07 +/- 5.62 nmol/L, P < 0.01).


CONCLUSIONS
JLJOL could scavenge the injury of free radical on organism.
Zhao
C Y
CY
First Affiliated Hospital of Medical School, Jinan University, Guangzhou 510630.
Shen
Y S
YS
Meng
H
H
D000818:Animals; D029481:Bronchitis, Chronic / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D016166:Free Radical Scavengers / Q000494:pharmacology; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D051379:Mice; D011897:Random Allocation; D013482:Superoxide Dismutase / Q000097:blood*
D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D008315:Malondialdehyde; D013482:Superoxide Dismutase