[Immunohistochemical study of the sinus mucosa during chronic maxillary sinusitis].
OBJECTIVE
To study the protective role of some immunocompetent cells and some humoral immune factors in the local mucosa during chronic sinusitis.


METHODS
Using immunohistochemical streptavidinbiotin peroxide complex (SABC) method to investigate the distribution and the numbers about the T-lymphocytes and subsets, B-cells, macrophages, NK cells, mast cells eosinophils, HLA-DR antigen and IgA, IgG, complement C3, lysozyme in the local mucosa of two type chronic sinusitis.


RESULTS
The numbers of T-lymphocytes, T helper/inducer cells, B-cells and macrophages in the mucosa of chronic sinusitis type 1 was significantly more than these in the healthy control (P < 0.01). The number of T-lymphocytes, T suppressor cells, B cells, mast cells and eosinophils in the type 2 was significantly more than these in the healthy control (P < 0.01). The ratio of the helper cells to T suppressor cells significant different in the two type chronic sinusitis.


CONCLUSIONS
The study showed that the infiltrating of immunocompetent cells was different between the two type chronic sinusitis.
Li
Y Z
YZ
Department of Otolaryngology, Affiliated Hospital of Taishan Medical College, Taian 271000.
Fang
Z S
ZS
Zhao
W B
WB
Zhou
Y
Y
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007150:Immunohistochemistry; D008297:Male; D015523:Maxillary Sinusitis / Q000276:immunology* / Q000473:pathology; D008875:Middle Aged; D009297:Nasal Mucosa / Q000276:immunology* / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology