title: [Evaluation of prevalent status of kala-azar in endemic area of Hubei Province].
abstract: OBJECTIVE
  To identify the diagnosis of 14 cases with "kala-azar" previously reported in Hubei Province since 1989 and to evaluate the present status of the disease.
  
  
  METHODS
  Bone marrow smear, immunological test (LDTand IFAT), mouse inoculation, fungi culture, vector (Phlebotomus) and reservoir host (dog) survey.
  
  
  RESULTS
  Among the 14 cases, 12 cases were progressive disseminated histoplasmois, one was an imported case and another one was a remnant skin type "kala-azar" case. An immunological survey was conducted during 1997-1999 in 25 townships located in 23 counties of 9 prefectures and cities. A total of 13,890 persons had been examined by LDT, the positive rate was 0.07%, no positive case was found among the persons under 40 years of age. During the survey, 1,756 persons had been examined by IFAT, the results were negative. No Phlebotomus chinensis had been found in the surveyed area. A total of 302 dogs were examined, no sick dog had been found.
  
  
  CONCLUSIONS
  Kala-azar has been eradicated in Hubei Province.
authors.affiliation: Institute of Parasitic Diseases, Hubei Academy of Medical Science, Wuhan 430079.
authors.forename: A F
authors.initials: AF
authors.lastname: Gui
authors.forename: S L
authors.initials: SL
authors.lastname: Zuo
authors.forename: J H
authors.initials: JH
authors.lastname: Wu
authors.forename: X E
authors.initials: XE
authors.lastname: Gui
authors.forename: L Q
authors.initials: LQ
authors.lastname: Hu
authors.forename: L D
authors.initials: LD
authors.lastname: Yang
authors.forename: S Q
authors.initials: SQ
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D002681:China / Q000453:epidemiology; D004285:Dogs; D005455:Fluorescent Antibody Technique; D006801:Humans; D007428:Intradermal Tests; D007893:Leishmania donovani / Q000276:immunology; D007898:Leishmaniasis, Visceral / Q000453:epidemiology*; D015995:Prevalence
chemical_list: D000913:Antibodies, Protozoan