Isolation of phytotoxic compounds from tree-of-heaven (Ailanthus altissima swingle).
The aqueous root extract of Ailanthus altissima showed allelopathic activity against radish (Raphanus sativus L. cv. "Saxa"), garden cress (Lepidium sativum L.), and purslane (Portulaca oleracea L.) seeds. A bioassay-oriented purification of active extracts, chromatographic fractions, and compounds demonstrated dose-dependent activity on germination and radicle growth of test seeds; radish seed was the most sensitive to allelochemicals. Active compounds have been isolated: ailanthone, ailanthinone, chaparrine, and ailanthinol B (quassinoid derivatives); the alkaloid 1-methoxycanthin-6-one is not active. The compound with greatest inhibitory activity is ailanthone. The data obtained suggest a possible use of tree-of-heaven root extracts or of its active constituents as natural herbicides.
De Feo
Vincenzo
V
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano (Salerno), Italy. defeo@unisa.it
De Martino
Laura
L
Quaranta
Emilia
E
Pizza
Cosimo
C
D032268:Ailanthus / Q000737:chemistry*; D001681:Biological Assay; D018525:Germination / Q000187:drug effects; D006540:Herbicides / Q000302:isolation & purification* / Q000494:pharmacology; D029686:Lepidium / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry*; D031822:Portulaca / Q000187:drug effects; D036702:Quassins / Q000302:isolation & purification / Q000494:pharmacology; D031224:Raphanus / Q000187:drug effects; D012639:Seeds / Q000187:drug effects / Q000254:growth & development
D006540:Herbicides; D010936:Plant Extracts; D036702:Quassins; C029825:ailanthone