title: Homogeneous Ir-192 afterloading-flab-irradiation of plane surfaces.
abstract: Homogeneous irradiation of plane targets by Ir-192 afterloading flabs made by a parallel series of linear applicators can be time-consuming even with modern planning systems. The aim of the present study was to develop an algorithm that supplies homogeneous dose distributions in an arbitrary given plane in parallel to the equipped plane of a flab. The edge and corner positions of the flab are of particular importance. The identity of the dose in the optimisation distance above the flab centre, corners, and middle of the flab edges, leads to a strict relation of the respective dwell weights. Formulas can be derived that allow the calculation of the dwell times. The dimensioning of the flab can be rapidly adapted to new conditions. A comparison with the results of Nucletron PLATO-BPS for applicator-applicator distances and step sizes of 1 cm at optimisation distances of 10, 20, 30, and 40 mm and various flab sizes (3 x 3, 9 x 9, and 15 x 15 cm2) shows the following results: The standard deviation of the proposed algorithm is sometimes slightly higher than the results of the commercial planning system, whereas the underdosage at the flab edges is usually smaller. The effort for planning and preparation of the irradiation, for example using a Nucletron HDR, is below 5 minutes--a considerable reduction of planning time.
authors.affiliation: Klinik und Poliklinik für Strahlentherapie, Julius-Maximilians-Universität Würzburg. K.Bratengeier@strahlentherapie.uni-wuerzburg.de
authors.forename: Klaus
authors.initials: K
authors.lastname: Bratengeier
authors.forename: Thomas
authors.initials: T
authors.lastname: Krieger
mesh_terms: D002138:Calibration; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008962:Models, Theoretical; D011880:Radiotherapy Planning, Computer-Assisted; D013997:Time Factors
chemical_list: D007496:Iridium Radioisotopes