title: Ameloblastic carcinoma: report of an aggressive case with multiple bony metastases.
abstract: Ameloblastic carcinoma is a rare primary tumor of the maxillofacial skeleton with a distinct predilection for the mandible. These lesions may initially show histologic features of ameloblastoma that dedifferentiate over time. Other ameloblastic carcinomas initially present with morphologic features suggestive of ameloblastoma with areas of epithelial dedifferentiation. We herein report a rare case of aggressive ameloblastic carcinoma in a 22-year-old white man who developed widespread bony metastases and expired 4 years after initial diagnosis.
authors.affiliation: Departments of Head and Neck Surgery and dagger Surgical Pathology, Roswell Park Cancer Institute, Buffalo, NY.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Datta
authors.forename: Janet S
authors.initials: JS
authors.lastname: Winston
authors.forename: Gustavo
authors.initials: G
authors.lastname: Diaz-Reyes
authors.forename: Thom R
authors.initials: TR
authors.lastname: Loree
authors.forename: Larry
authors.initials: L
authors.lastname: Myers
authors.forename: M Abraham
authors.initials: MA
authors.lastname: Kuriakose
authors.forename: Nestor R
authors.initials: NR
authors.lastname: Rigual
authors.forename: Wesley L
authors.initials: WL
authors.lastname: Hicks
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D001859:Bone Neoplasms / Q000556:secondary; D002277:Carcinoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery; D037981:Neck Dissection; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery