title: [Gastric ulcer and Helicobacter pylori infection].
abstract: Helicobacter pylori infection and the use of non-steroidal anti-inflammatory drugs (NSAID) are considered to be the two major risk factors implicated in the development of gastric ulcer. Helicobacter pylori infection related chronic gastritis is known to be the underlying condition which may lead to gastric ulcer. Development of gastric ulcer as the consequence of underlying chronic gastritis is caused by many factors. Treating Helicobacter pylori infection entails the healing of gastric ulcer, it concomitantly prevents recurrences and complications of gastric ulcer, primarily bleeding, and changes the natural course of gastric ulcer disease. Continuation of antisecretory maintenance treatment beyond ulcus healing and eradication of Helicobacter pylori infection is only indicated in risk groups. Patients with gastric ulcer caused by NSAID use are managed with antisecretory therapy.
authors.affiliation: Klinicka bolnica Merkur Medicinskog fakulteta Sveucilista u Zagrebu, Zajceva 19, 10000 Zagreb.
authors.forename: Mirjana
authors.initials: M
authors.lastname: Tićak
authors.forename: Marija
authors.initials: M
authors.lastname: Prskalo
authors.forename: Branka
authors.initials: B
authors.lastname: Sabarić
authors.forename: Mara
authors.initials: M
authors.lastname: Dominis
authors.forename: Bruno
authors.initials: B
authors.lastname: Skurla
authors.forename: Sonja
authors.initials: S
authors.lastname: Dzebro
authors.forename: Tajana
authors.initials: T
authors.lastname: Filipec
authors.forename: Vesna
authors.initials: V
authors.lastname: Colić-Cvrlje
authors.forename: Slavica
authors.initials: S
authors.lastname: Naumovski-Mihalić
authors.forename: Branko
authors.initials: B
authors.lastname: Papa
authors.forename: Davor
authors.initials: D
authors.lastname: Jelić
authors.forename: Miroslava
authors.initials: M
authors.lastname: Katicić
mesh_terms: D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D016481:Helicobacter Infections / Q000175:diagnosis / Q000628:therapy; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D013276:Stomach Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy