title: Effects of pesticides on DNA and protein of shrimp larvae Litopenaeus stylirostris of the California Gulf.
abstract: Recently, diverse pathologies and massive mortalities have been presented in shrimp hatcheries located along the California Gulf; therefore, toxic responses of shrimp larvae were used as biomarkers of pesticide pollution, because in this region intensive agriculture is practiced. Shrimp larvae were exposed to DDT, azinphosmethyl, permethrine, parathion, chlorpyrifos, malathion, endosulfan, and carbaryl, in order to determine LC50, DNA adducts and/or breaks, and total protein in larvae. The results indicate reductions in protein and DNA in larvae exposed to these pesticides, and in those exposed to DDT, breaks and/or adducts were registered. It is possible that pesticide pollution is a cause of these problems, because reduction in protein indicates a decrease in larvae growth rate and DNA breaks or adducts have been related to pathologies and carcinogenesis in many aquatic organisms.
authors.affiliation: Facultad de Ciencias del Mar, Universidad Autónoma de Sinaloa, Paseo Claussen s/n, Mazatán, Sin, C.P. 82000 Mexico.
authors.forename: J Guillermo
authors.initials: JG
authors.lastname: Galindo Reyes
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Leyva
authors.forename: Olivia A
authors.initials: OA
authors.lastname: Millan
authors.forename: Guadalupe A
authors.initials: GA
authors.lastname: Lazcano
mesh_terms: D000818:Animals; D004247:DNA / Q000032:analysis*; D018736:DNA Adducts / Q000032:analysis; D004784:Environmental Monitoring; D007814:Larva / Q000187:drug effects / Q000378:metabolism; D007928:Lethal Dose 50; D008800:Mexico; D033561:Penaeidae / Q000187:drug effects* / Q000378:metabolism; D010575:Pesticides / Q000633:toxicity*; D011506:Proteins / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D018736:DNA Adducts; D010575:Pesticides; D011506:Proteins; D014874:Water Pollutants, Chemical; D004247:DNA