title: Mixture ratios of local bone to artificial bone in lumbar posterolateral fusion.
abstract: There have been no reports on the effects of the mixture ratio of local bone graft to artificial bone on the outcome of intervertebral bone fusion. The purpose of this study was to determine whether the mixture ratio of local bone removed from laminae and spinous processes to apatite- and wollastonite-containing glass ceramic (AWGC) granules affected fusion rates in spinal fusion. Posterolateral lumbar fusion at two levels without spinal instrumentation was performed in 35 patients who were diagnosed with lumbar spinal canal stenosis. The patients were randomly divided into three groups, each of which received a different mixture ratio of local bone to AWGC granules: 2:1, 1:1, and 1:2. The total mass of grafted bone was 20 g in all three groups. The fusion rate was approximately 80% in all three groups. Our results indicate that lumbar posterolateral fusion can be successfully achieved even when the mixture ratio of local bone graft to AWGC granules is 1:2.
authors.affiliation: Department of Orthopaedic Surgery, Mei University Faculty of Medicine, Tsu, Japan. ykasai@clin.medic.mie-u.ac.jp
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kasai
authors.forename: Kenji
authors.initials: K
authors.lastname: Takegami
authors.forename: Atsumasa
authors.initials: A
authors.lastname: Uchida
mesh_terms: D000368:Aged; D001031:Apatites / Q000627:therapeutic use; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D017610:Calcium Compounds / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011786:Quality Control; D011859:Radiography; D017640:Silicates / Q000627:therapeutic use; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D013130:Spinal Stenosis / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D017610:Calcium Compounds; D017640:Silicates; C031293:calcium silicate