[Central pontine and extra-pontine myelinolysis in an alcoholic patient without hydro-electrolyte disturbances: case report].
Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) are different presentations of a demyelinating disorder of the brain more commonly associated with rapid correction of hyponatremia, spastic tetraparesia and pseudo-bulbar palsy. There are in the literature a few cases of CPM/EPM in patients without electrolyte disturbances. We report the case of a 39 year-old man with severe alcoholism, who presented with spastic tetraparesis and palsy of several cranial nerves, associated with lesions in the magnetic resonance compatible with CPM/EPM. The patient had a good follow-up after pulse therapy with corticosteroids.
Germiniani
Francisco Manoel B
FM
Serviço de Neurologia, Departamento de Clinica Medica, Hospital de Clinicas da Universidade Federal do Parana, Curitiba, PR, Brasil.
Roriz
Mauricio
M
Nabhan
Samir K
SK
Teive
Helio A G
HA
Werneck
Lineu C
LC
D000328:Adult; D000437:Alcoholism / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors; D014882:Water-Electrolyte Balance