title: Molecular strategies to study Plasmodium-mosquito interactions.
abstract: It is widely known that malaria kills millions of people every year. Less well recognized is the fact that the situation is steadily deteriorating for a lack of effective means to counter the disease. An essential first step towards the development of new approaches to fight malaria is a thorough understanding of the mechanisms that direct parasite growth and differentiation, including parasite-host interactions. This article reviews recent achievements and introduces some promising new technologies and approaches for studying host-parasite interactions.
authors.affiliation: Case Western Reserve University, Department of Genetics, 10900 Euclid Avenue, Cleveland, Ohio 44106-4955, USA.
authors.forename: Anil
authors.initials: A
authors.lastname: Ghosh
authors.forename: Prakash
authors.initials: P
authors.lastname: Srinivasan
authors.forename: Eappen G
authors.initials: EG
authors.lastname: Abraham
authors.forename: Hisashi
authors.initials: H
authors.lastname: Fujioka
authors.forename: Marcelo
authors.initials: M
authors.lastname: Jacobs-Lorena
mesh_terms: D000818:Animals; D009033:Culicidae / Q000235:genetics / Q000469:parasitology* / Q000502:physiology; D005786:Gene Expression Regulation; D006790:Host-Parasite Interactions; D006801:Humans; D007303:Insect Vectors / Q000235:genetics / Q000469:parasitology* / Q000502:physiology; D008018:Life Cycle Stages; D008288:Malaria / Q000469:parasitology / Q000635:transmission; D020411:Oligonucleotide Array Sequence Analysis; D010961:Plasmodium / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D040901:Proteomics