Prevalence of Chlamydia trachomatis in human immunodeficiency virus-infected women in Cuba.
To determine the prevalence rates and serovar distribution of Chlamydia trachomatis cervical infections in Cuban women, two different groups were selected. Group I consisted of 60 human immunodeficiency virus (HIV-1) seropositive women from different regions of Cuba and group II of 60 randomly selected women HIV seronegative and apparently healthy. C. trachomatis was detected in cervical scrapes by mean of nested polymerase chain reaction (PCR) specific for major out membrane protein. The overall prevalence rate of C. trachomatis in cervical scrapes determined by nested PCR was 10% in group I and the estimated prevalence was 6.6% for group II; 83.3% of HIV seropositive women with C. trachomatis infection reported history of pelvic inflammatory disease followed by cervicitis (50%). The control group C. trachomatis-infected women referred a history of cervicitis in 75% of cases. Other reports in the latter group included infertility and pelvic inflamatory disease in 50%. The present study is the first report of C. trachomatis prevalence in Cuba. It showed that there was not significantly difference in the prevalence rate of C. trachomatis between both groups.
Kouri
Vivian
V
Departamento de Virología, Instituto de Medicina Tropical 'Pedro Kouri', Ciudad de la Habana, Cuba. vkouri@ipk.sld.cu
Cartaya
Judith
J
Rodríguez
María E
ME
Muné
Mayra
M
Soto
Yudira
Y
Resik
Sonia
S
Bravo
Jose
J
Llop
Alina
A
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D002692:Chlamydia trachomatis; D003462:Cuba / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity / Q000453:epidemiology* / Q000382:microbiology; D015497:HIV-1; D006801:Humans; D008875:Middle Aged; D010298:Parity; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D018272:Porins / Q000032:analysis; D015995:Prevalence; D012307:Risk Factors
D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis