title: Correlation between structure, aggregation behaviour and cellular toxicity of anti-HIV catanionic analogues of galactosylceramide.
abstract: The self-association process of catanionic analogues of galactosylceramide and in particular the arrangement of their hydrophobic part seems to play a key role in their cellular toxicity
authors.affiliation: Laboratoire des Interactions Moléculaire et Réactivité Chimique et Photochimique, CNRS UMR 5623, Université P. Sabatier, 118 route de Narbonne, 31062 Toulouse cedex, France. blanzat@chimie.ups-tlse.fr
authors.forename: Muriel
authors.initials: M
authors.lastname: Blanzat
authors.forename: Emile
authors.initials: E
authors.lastname: Perez
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rico-Lattes
authors.forename: Armand
authors.initials: A
authors.lastname: Lattesa
authors.forename: Annette
authors.initials: A
authors.lastname: Gulik
mesh_terms: D019380:Anti-HIV Agents / Q000737:chemistry* / Q000494:pharmacology / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects*; D019281:Dimerization; D005699:Galactosylceramides / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: D019380:Anti-HIV Agents; D005699:Galactosylceramides