Androgens and aging men.
This article underlines the hormonal and clinical events characterizing the so-called andropause, as they may be described from an extensive review of the literature and some data obtained with the French colleagues of the author. Evidence-based hormonal intervention has to be positioned against anti-aging entrepreneurs who peddle hormones at random. The desequilibrium in aging men between the unchanged level of plasma cortisol and the profound decrease of androgens deserves cautious studies to eventually oppose this unbalanced hormonal situation effectively and safely.
Baulieu
Etienne-Emile
EE
INSERM U488 and Collège de France, 94276 Le Kremlin-Bicêtre, France. baulieu@kb.inserm.fr
D000375:Aging / Q000502:physiology*; D000728:Androgens / Q000378:metabolism*; D015519:Bone Density; D003687:Dehydroepiandrosterone / Q000008:administration & dosage / Q000378:metabolism; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007989:Libido / Q000502:physiology; D008297:Male; D008593:Menopause / Q000502:physiology; D013223:Statistics as Topic; D013739:Testosterone / Q000097:blood*
D000728:Androgens; D013739:Testosterone; D003687:Dehydroepiandrosterone; D004958:Estradiol