title: Malignant pleomorphic adenoma (malignant mixed tumor) of the trachea: a case report and review of the literature.
abstract: A case of malignant mixed tumor of the trachea in a 56-year-old man is described. His tumor was removed by segmental tracheal resection, and end-to-end anastomosis was performed. Histologically, the tumor was characterized by a biphasic composition showing admixtures of epithelial elements in varying proportions; these were cytologically atypical with prominent mitotic figures. However, stromal elements were osteoid and mixoid with a benign appearance. The patient had no evidence of disease in the head and neck region and had no history of previous surgery for a salivary gland tumor. These findings were interpreted as indicative of malignant pleomorphic adenoma of the trachea.
authors.affiliation: Department of Pathology, Atatürk Center for Chest Disease and Thoracic Surgery, M.Esat Bozkurt Cad., Kültür Apt. No. 5/17 Kolej, Ankara, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Demirağ
authors.forename: Salih
authors.initials: S
authors.lastname: Topçu
authors.forename: Cüneyt
authors.initials: C
authors.lastname: Kurul
authors.forename: Leyla
authors.initials: L
authors.lastname: Memiş
authors.forename: Tamer
authors.initials: T
authors.lastname: Altinok
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology; D000714:Anastomosis, Surgical; D001707:Biopsy, Needle; D013505:Digestive System Surgical Procedures / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D018198:Mixed Tumor, Malignant / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D014134:Tracheal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D016896:Treatment Outcome