title: Investigations on the wear behaviour of the temporary PMMA-based hip Spacer-G.
abstract: Total hip replacement has become one of the most successful orthopaedic procedures. However, complications due to infections may give serious problems and have devastating consequences for the hip implant. The use of a temporary three-dimensional polymethylmethacrylate (PMMA) cement spacer may be an alternative to solve infections in hip implants, improving the lives of patients awaiting reimplantation. In order to evaluate their wear behaviour, five PMMA Spacer-G femoral heads were tested against five post-mortem pelves in a hip joint simulator with bovine calf serum as lubricant. The surface of the worn spacers was characterized by scanning electron microscopy (SEM) analysis; all the samples revealed a similar morphology, showing areas characterized by different degrees of wear. Particle debris was isolated from the lubricant and PMMA particles and bone fractions were quantified. The amount of debris was found to be higher than where no-temporary prostheses were used. However, this result is acceptable since wear debris is removed by lavage irrigation when the Spacer-G is explanted. On the basis of these data, it is considered that the use of the cement Spacer-G could be a promising approach to the treatment of complicated infections of the hip joint. Therefore, Spacer-G is worthy of further research.
authors.affiliation: Laboratorio di Tecnologia Medica, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Affatato
authors.forename: A
authors.initials: A
authors.lastname: Mattarozzi
authors.forename: P
authors.initials: P
authors.lastname: Taddei
authors.forename: P
authors.initials: P
authors.lastname: Robotti
authors.forename: R
authors.initials: R
authors.lastname: Soffiatti
authors.forename: A
authors.initials: A
authors.lastname: Sudanese
authors.forename: A
authors.initials: A
authors.lastname: Toni
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation; D002102:Cadaver; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use; D019245:Compressive Strength; D019544:Equipment Failure Analysis / Q000295:instrumentation / Q000379:methods; D017276:Friction; D006622:Hip Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008153:Lubrication; D008855:Microscopy, Electron, Scanning; D019904:Polymethyl Methacrylate; D011475:Prosthesis Failure; D012086:Reoperation / Q000295:instrumentation; D016138:Walking; D016474:Weight-Bearing
chemical_list: D020099:Coated Materials, Biocompatible; D019904:Polymethyl Methacrylate