[Clinical and bacteriology observation on intraoperation usage of tarivid otic solution in treatment of chronic otitis media with cholesteatoma].
OBJECTIVE
To determine the effect and safety of Tarivid (oflorxacin) otic solution used during the operation in treatment for chronic otitis media with cholesteatoma.


METHODS
42 patients were divided into two groups. In Tarivid group, 23 patients' operative cavities were soaked with 0.3% Tarivid, while other 19 patients' operative cavities in boric acid group were soaked with 4% boric acid during the open mastoidectomy with tympanoplasty.


RESULTS
The recovery rate was 82.6% and 50% respectively. There was significant difference between two groups (P < 0.05). No side effect was observed.


CONCLUSIONS
It shows that using Tarivid otic solution in the operation can improve the outcome of the operation and has high security.
Gao
Q
Q
Department of Otolaryngology, Tongji Hospital, Tongji Medical University, Wuhan 430030.
Liu
Z
Z
Cui
Y
Y
D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D018424:Cholesteatoma, Middle Ear / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage*; D010033:Otitis Media / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D019999:Pharmaceutical Solutions / Q000008:administration & dosage; D014433:Tympanoplasty
D000890:Anti-Infective Agents; D019999:Pharmaceutical Solutions; D015242:Ofloxacin