title: Coronary revascularization in the 21st century. Emphasis on contributions by Japanese surgeons.
abstract: The first three decades of coronary artery surgery have provided the foundation for the next century of this evolution. It is apparent that a multitude of events including the development of cardioplegia, improving surgical instrumentation, technological advances including endoscopic approaches and computer assisted robotics and biologic discoveries such as the role of the endothelium have provided the underpinnings for improved surgical outcomes. However, the single most important determinant of late results is the type of bypass conduit used for grafting. Thus, use of the left internal thoracic artery (ITA) grafted to the left anterior descending coronary is a more important determinant of survival than is any other factor (progression of coronary artery disease, increased age, poor left ventricular function, diabetes, female gender and off-pump operations). Use of two ITAs provides further benefit and it is likely that three or more arterial conduits will be shown to be advantageous in this regard in due time. Japanese cardiothoracic surgeons have made significant contributions to the continuing evolution of coronary bypass surgery and particularly to the advance of arterial conduits. This report will address those contributions to this evolution.
authors.affiliation: Washington University School of Medicine, St. Louis, Missouri, USA. barnerh@msnotes.wustl.edu
authors.forename: Hendrick B
authors.initials: HB
authors.lastname: Barner
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods / Q000639:trends*; D003324:Coronary Artery Disease / Q000209:etiology; D004730:Endothelium, Vascular / Q000473:pathology / Q000502:physiology; D019074:Epigastric Arteries / Q000637:transplantation; D006801:Humans; D008323:Mammary Arteries / Q000637:transplantation; D009204:Myocardial Revascularization / Q000639:trends*; D017534:Radial Artery / Q000637:transplantation; D012501:Saphenous Vein / Q000637:transplantation; D014654:Vascular Patency