title: Impact of comorbid personality disorder on violence in psychosis: report from the UK700 trial.
abstract: BACKGROUND
  The impact of comorbid personality disorder on the occurrence of violence in psychosis has not been fully explored.
  
  
  OBJECTIVE
  To examine the association between comorbid personality disorder and violence in community-dwelling patients with psychosis.
  
  
  METHODS
  A total of 670 patients with established psychotic illness were screened for comorbid personality disorder. Physical assault was measured from multiple data sources over the subsequent 2 years. Logistic regression was used to assess whether the presence of comorbid personality disorder predicted violence in the sample.
  
  
  RESULTS
  A total of 186 patients (28%) were rated as having a comorbid personality disorder. Patients with comorbid personality disorder were significantly more likely to behave violently over the 2-year period of the trial (adjusted odds ratio=1.71, 95% CI 1.05-2.79).
  
  
  CONCLUSIONS
  Comorbid personality disorder is independently associated with an increased risk of violent behaviour in psychosis.
authors.affiliation: Health Services Research Department, Institute of Psychiatry, London, UK. paul.moran@iop.kcl.ac.uk
authors.forename: Paul
authors.initials: P
authors.lastname: Moran
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Walsh
authors.forename: Peter
authors.initials: P
authors.lastname: Tyrer
authors.forename: Tom
authors.initials: T
authors.lastname: Burns
authors.forename: Francis
authors.initials: F
authors.lastname: Creed
authors.forename: Tom
authors.initials: T
authors.lastname: Fahy
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010552:Personality Assessment; D010554:Personality Disorders / Q000523:psychology*; D011618:Psychotic Disorders / Q000523:psychology*; D012307:Risk Factors; D012565:Schizophrenic Psychology; D014754:Violence / Q000523:psychology*