title: [Congestive heart failure and paraoxonase].
abstract: OBJECTIVE
  To determine the changes of paraoxonase activity in patients with heart failure.
  
  
  METHODS
  The serum paraoxonase (PON) activity of the heart failure group and controls was measured with phenylacetate as the substrate.
  
  
  RESULTS
  The serum PON activity of the heart failure patients significantly decreased as compared with the controls; after the treatment, the PON activity of heart failure was largely elevated; and the PON activity of the patients with heart failure was negatively correlated with tumor necrosis factor-alpha.
  
  
  CONCLUSIONS
  The PON activity of patients with congestive heart failure significantly decreases.
authors.affiliation: Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Xiao-mei
authors.initials: XM
authors.lastname: Xie
authors.forename: Shui-ping
authors.initials: SP
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D043303:Aryldialkylphosphatase; D004070:Digitalis / Q000187:drug effects; D004950:Esterases / Q000378:metabolism*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000201:enzymology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D014409:Tumor Necrosis Factor-alpha; D004950:Esterases; D043303:Aryldialkylphosphatase