Simultaneous kidney-pancreas transplantation in a patient with small lymphocytic lymphoma.
BACKGROUND
Experience with organ transplantation in patients with indolent lymphoma is limited, and it is unknown how the natural history of the disease is altered by chronic immunosuppressive therapy.


METHODS
A patient with type 1 diabetes and renal failure who underwent simultaneous kidney-pancreas transplantation was found to have stage IV small lymphocytic lymphoma at the time of transplantation. He received quadruple immunosuppressive therapy using interleukin (IL)-2 receptor antibody, tacrolimus, mycophenolate mofetil, and prednisone.


RESULTS
Patient is doing well 3 years posttransplant with excellent graft function of both the kidney and pancreas without any evidence of progression of the disease.


CONCLUSIONS
Indolent lymphoma should not be considered an absolute contraindication to organ transplantation.
Romero
A  L  Ramon
A
Section of Transplantation, Department of Surgery, University of Kentucky, Lexington, KY 40536, USA.
Reddy
K Sudhakar
KS
Johnston
Thomas D
TD
Waid
Thomas W
TW
Wade MeKeown
J
J
Khan
Taqi
T
Karounos
Dennis
D
Doukas
Michael
M
Samayoa
Luis
L
Ranjan
Dinesh
D
D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000601:surgery*; D006801:Humans; D016030:Kidney Transplantation; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation; D051437:Renal Insufficiency / Q000150:complications / Q000601:surgery*