title: Rhinosporidiosis--a clinicopathological study of 34 cases.
abstract: Rhinosporidiosis was the commonest (68%) fungal lesion encountered during the period of 11 1/2 years from January 1987 to July 1998. Men in 2nd, 3rd, 4th decade were commonly affected. Nose and nasopharynx were the commonest (85%) sites involved followed by ocular tissue (9%). One patient had involvement of bone (tibia). Generally a lymphoplasmacytic response was observed in all cases. Polymorphonuclear leukocytic response mostly observed at the site of rupture of sporangia. Epithelioid cell granulomatous and giant cell response observed in 47% of cases. Transepithelial migration of sporangia observed in 76% of cases. Rhinosporidium seeberi could be easily identified in haematoxylin and eosin stained sections. The walls of young trophic forms are delineated well with the PAS stain and verhoeff van Gieson stain.
authors.affiliation: Department of Pathology, Karnataka Institute of Medical Sciences, Hubli, Karnataka.
authors.forename: J H
authors.initials: JH
authors.lastname: Makannavar
authors.forename: S S
authors.initials: SS
authors.lastname: Chavan
mesh_terms: D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000382:microbiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012227:Rhinosporidiosis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D012228:Rhinosporidium / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification*; D016622:Silver Staining; D018461:Soft Tissue Infections / Q000000981:diagnostic imaging / Q000382:microbiology*; D013172:Spores, Fungal / Q000302:isolation & purification; D013194:Staining and Labeling; D013977:Tibia