[Study on the relationship between microvascular density and prognosis in laryngeal cancer].
OBJECTIVE
To study the relationship between the microvascular density(MVD) and the prognosis in laryngeal cancer.


METHODS
Microvessel quantitation in 31 cases of laryngeal cancer was done with factor VIII-related antibody and SABC method.


RESULTS
The quantitation of microvessels in laryngeal cancer were negative of histologic grade and type, but were significantly different (P < 0.05) between metastasis (10.23 +/- 0.78) and without metastasis(6.38 +/- 0.33) two years after operation.


CONCLUSIONS
The angiogenesis of laryngeal cancer is correlated with the lymph node metastasis and prognosis.
Lu
Y Y
YY
Department of Otorhinolaryngology, First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003.
Shen
P
P
Ding
W
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology*; D011379:Prognosis