[Effect of qiongyugao on the action of DDP in inhibiting the division of GLC-82 cell strain in vitro].
OBJECTIVE
To observe the effect of Qiongyugao (QYG) on the action of DDP in inhibiting the division of GLC-82 cell strain in vitro.


METHODS
The method of serum pharmacology was used in observing the morphological change of the cancer cells. By accounting the number of the live cells of each day during 6 days respectively, the growth curve was drawn up. The effects of the three groups on the cancer cells apoptosis of GLC-82 cell strain were analysed by FACS. RESULLTS: The growth of the cancer cells in control group (normal saline) was much better than the other two groups; in chemical therapy group (DDP), the number of the live cells almost kept steady; the number of the live cells in combined group(DDP plus QYG) became even lower. QYG could enhance the action of DDP in inducing the apoptosis of GLC-82 cells strain remarkably.


CONCLUSIONS
QYG can enhance the effects of chemotherapy in inhibiting cancer cells division and inducing their apoptosis.
Zhang
Q
Q
Jinan University, Guangzhou 510632.
Xie
Q
Q
Chen
X
X
Sun
L
L
Ye
K
K
Tang
C
C
D000230:Adenocarcinoma / Q000473:pathology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D002945:Cisplatin / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005434:Flow Cytometry; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D002945:Cisplatin