[Isolation and identification of active constituent of Toddalia asiatica in cardiovascular system].
The ethereal extract from the crude ethanolic extract of Toddalia asiatica was chromatographed on silica gel and tested on biological activity. A crystalline was obtained and confirmed as an active constituent in cardiovascular system. The active constituent was identified as isopimpinellin on the basis of chemical method and spectral analysis.
Guo
S
S
Department of Chemistry, Jinan University, Guangzhou 510632.
Li
S
S
Peng
Z
Z
Ren
X
X
D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D011564:Furocoumarins / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D066298:In Vitro Techniques; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D027821:Rutaceae / Q000737:chemistry*; D014661:Vasoconstriction / Q000187:drug effects
D002121:Calcium Channel Blockers; D004365:Drugs, Chinese Herbal; D011564:Furocoumarins; C015304:isopimpinellin