[Chemical constituents from marine fungus Penicillium thomii].
OBJECTIVE
To investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach.


METHODS
The constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis.


RESULTS
Five compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii.


CONCLUSIONS
Penicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.
Jiang
Ting
T
National Research Laboratories of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
Tian
Li
L
Guo
Ai-hua
AH
Fu
Hong-zheng
HZ
Pei
Yue-hu
YH
Lin
Wen-han
WH
D000818:Animals; D008968:Molecular Conformation; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry* / Q000302:isolation & purification; D012615:Sea Anemones / Q000382:microbiology*; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification*
D044004:Xanthones; C479300:penicillixanthone A