title: Did quadruplex DNA play a role in the evolution of the eukaryotic linear chromosome?
abstract: The current evidence on prokaryotic linear chromosomes, the eukaryotes that do not use telomerase and quadruplex DNA has been considered. This has lead to the suggestion that quadruplex DNA may have played a role in the evolution of the protection linear chromosomes rather than in overcoming the end replication problem.
authors.affiliation: Chemistry Department, Wesleyan University, Middletown, CT 06459, USA.
authors.forename: Haribabu
authors.initials: H
authors.lastname: Arthanari
authors.forename: Philip H
authors.initials: PH
authors.lastname: Bolton
mesh_terms: D004247:DNA / Q000737:chemistry / Q000502:physiology*; D019143:Evolution, Molecular; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA