title: Emergence of an IMP-like metallo-enzyme in an Acinetobacter baumannii clinical strain from a Brazilian teaching hospital.
abstract: Multidrug-resistant Acinetobacter spp. constitute a serious cause of nosocomial infection in Brazilian hospitals. This manuscript reports the first appearance of an IMP-like metallo-beta-lactamase encountered in a clinical isolate of A. baumannii from a Brazilian teaching hospital.
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Universidade Federal de São Paulo, São Paulo, Brazil. galesac@aol.com
authors.forename: Ana C
authors.initials: AC
authors.lastname: Gales
authors.forename: Maria C B
authors.initials: MC
authors.lastname: Tognim
authors.forename: Adriana O
authors.initials: AO
authors.lastname: Reis
authors.forename: Ronald N
authors.initials: RN
authors.lastname: Jones
authors.forename: Hélio S
authors.initials: HS
authors.lastname: Sader
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy / Q000453:epidemiology; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000201:enzymology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D001938:Brazil / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D018432:Drug Resistance, Multiple; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D001618:beta-Lactamases / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; C409201:beta-lactamase IMP-1; D001618:beta-Lactamases