Iridium-catalyzed Oppenauer oxidations of primary alcohols using acetone or 2-butanone as oxidant.
The first Oppenauer oxidation of primary alcohols with acetone or 2-butanone by an amino alcohol-based Ir bifunctional catalyst was accomplished. The reaction proceeds with 1 mol % catalyst in acetone or 2-butanone at 30-80 degrees C to give the corresponding aldehydes in 33-96% yield.
Suzuki
Takeyuki
T
Department of Synthetic Organic Chemistry, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-Ku, Sendai, Miyagi 981-8558, Japan.
Morita
Kenji
K
Tsuchida
Mika
M
Hiroi
Kunio
K