title: Nephrotic syndrome in a patient with intravascular lymphomatosis.
abstract: The association of malignancy with nephrotic syndrome and renal histopathologic abnormalities is well documented. We report a case of intravascular lymphomatosis (IVL) presenting as nephrotic syndrome which was diagnosed by renal biopsy. Histological examination of the renal biopsy specimens showed dissemination of neoplastic lymphoid cells throughout the glomerular capillary bed. These tumor cells were positive for CD20. Since the nephrotic syndrome improved with treatment of the lymphoma, intravascular lymphomatosis may well have played an important role in the pathogenesis of minimal change nephrotic syndrome in this patient.
authors.affiliation: Department of Internal Medicine, Hamanomachi General Hospital, Fukuoka.
authors.forename: Haruko
authors.initials: H
authors.lastname: Kakumitsu
authors.forename: Masakazu
authors.initials: M
authors.lastname: Higuchi
authors.forename: Kenji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Tsunefumi
authors.initials: T
authors.lastname: Shibuya
mesh_terms: D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D019043:Vascular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology