title: Primary dural low grade BCL-2 negative follicular lymphoma: a case report.
abstract: We report a case of low-grade follicular lymphoma presenting as a primary lesion in the intracranial dura. Based on the preoperative MRI, our patient was presumed to have meningioma. A surgical excision was performed and the histology showed features of a grade 1 follicular lymphoma predominately small-cleaved cell type. Postoperative investigations confirmed that it was the only site of involvement. The patient then received cranial radiotherapy and she is doing well with a follow up period of 18 months. To the best of our knowledge, it is the first case of a primary dural grade 1 follicular lymphoma, small-cleaved cell type.
authors.affiliation: Department of Radiation Oncology, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
authors.forename: Sushil
authors.initials: S
authors.lastname: Beriwal
authors.forename: J Steve
authors.initials: JS
authors.lastname: Hou
authors.forename: Curtis
authors.initials: C
authors.lastname: Miyamoto
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Garcia-Young
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D004388:Dura Mater / Q000473:pathology; D016326:Extracellular Matrix Proteins; D005260:Female; D006801:Humans; D008224:Lymphoma, Follicular / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D015260:Neprilysin / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism
chemical_list: C490607:ECM1 protein, human; D016326:Extracellular Matrix Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D015260:Neprilysin