title: Peripheral sensory neuropathy associated with short-term oral acitretin therapy.
abstract: A 57-year-old female patient with widespread chronic plaque psoriasis and a 32-year-old male patient with severe oral lichen planus are reported, who developed sensory symptoms in the extremities 3 and 4 months after the onset of oral acitretin therapy, respectively. Both patients showed clinical and electrophysiological evidence of a sensory peripheral neuropathy, which completely resolved 2 and 2.5 years after discontinuation of oral acitretin administration, respectively.
authors.affiliation: Department of Dermatology, University of Patras, Greece. tsambaos@med.upatras.gr
authors.forename: D
authors.initials: D
authors.lastname: Tsambaos
authors.forename: T
authors.initials: T
authors.lastname: Sakkis
authors.forename: E
authors.initials: E
authors.lastname: Chroni
authors.forename: K
authors.initials: K
authors.lastname: Koniavitou
authors.forename: A
authors.initials: A
authors.lastname: Monastirli
authors.forename: E
authors.initials: E
authors.lastname: Pasmatzi
authors.forename: C
authors.initials: C
authors.lastname: Paschalis
mesh_terms: D017255:Acitretin / Q000008:administration & dosage / Q000009:adverse effects*; D000284:Administration, Oral; D000328:Adult; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D017676:Lichen Planus, Oral / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D011565:Psoriasis / Q000188:drug therapy
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin