['Proteomics': the mapping of all human proteins].
The genomes of many organisms, including humans, are now largely known. In the wake of this there is a need to identify and measure all proteins that are encoded by the genome (proteomics). This need leads to turbulent developments in the area of analytical techniques, such as two-dimensional electrophoresis, mass spectrometry, and protein chips. The rapidity of advancements justifies the expectation that in the next 5-10 years it will indeed become possible to determine the proteome of an organism or its components such as plasma, serum, or tissues. In combination with information on initiation and progress of disease, proteomics will contribute to improving health and to better primary and secondary prevention.
Reitsma
P H
PH
Academisch Medisch Centrum/Universiteit van Amsterdam, Laboratorium voor Experimentele Inwendige Geneeskunde, Meibergdreef 9, 1105 AZ Amsterdam. p.h.reitsma@amc.uva.nl
de Koster
Ch G
ChG
D030562:Databases, Protein; D015180:Electrophoresis, Gel, Two-Dimensional; D016678:Genome; D006801:Humans; D013058:Mass Spectrometry; D020543:Proteome / Q000737:chemistry*; D040901:Proteomics
D020543:Proteome