[Experimental research on drug evaluation of ibuprofen oral drop].
OBJECTIVE
To make a pharmaceutical comparison between ibuprofen oral drop and ibuprofen tablet.


METHODS
Using ibuprofen oral drop, we observed the anti-inflammatory and analgesic effects of ibuprofen oral drop on the inflammatory swelling of the rats' toe caused by diagonal carrageenin; its anti-thermic effect on the temperature rising of domestic rabbits caused by endotoxin; and its analgesic effect on mice's pain caused by acetic acid.


RESULTS
Ibuprofen had obvious anti-inflammatory and analgesic functions.


CONCLUSIONS
Ibuprofen oral drop has the same pesticide effect as that of ibuprofen tablet.
Zhan
Da-zhi
DZ
Health-care Section, Xiangya School of Medicine, Central South University, Changsha 410078, China.
Zhu
Zheng-gang
ZG
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology*; D004341:Drug Evaluation; D005260:Female; D007052:Ibuprofen / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D012996:Solutions; D013607:Tablets
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012996:Solutions; D013607:Tablets; D007052:Ibuprofen