[Effect of AMI on proliferative cycle phase of bone marrow cells in mice].
By using culture of bone marrow cells in vitro and flowcytometry, effect of Astragalus membranaceus injection (AMI) on proliferative cycle phase of bone marrow cells in normal and anemic mice was studied. AMI 40 micrograms/ml (concentration in culture system) can promote normal murine bone marrow cells (BMC) entering proliferative cycle phase (S + M/G2 phase), so do AMI 40 micrograms/ml and AMI 400 micrograms/ml to anemic murine BMC. The results suggested AMI maybe enhance hematopoietic function in mice.
Zhu
X
X
West China University of Medical Sciences, Chengdu 610041.
Zhu
B
B
D000740:Anemia / Q000097:blood / Q000473:pathology*; D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry*; D001854:Bone Marrow Cells / Q000187:drug effects / Q000473:pathology*; D002453:Cell Cycle / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005434:Flow Cytometry; D007267:Injections; D008297:Male; D051379:Mice
D004365:Drugs, Chinese Herbal