Homoisoflavonoids from Ophiopogon japonicus Ker-Gawler.
From the ethyl acetate extract of the tuberous roots of Ophiopogon japonicus (Liliaceae) eight known and five new homoisoflavonoidal compounds were isolated. The new compounds are 5,7-dihydroxy-8-methoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one (1), 7-hydroxy-5,8-dimethoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one (2), 5,7-dihydroxy-6,8-dimethyl-3-(4'-hydroxy-3'-methoxybenzyl)chroman-4-one (3), 2,5,7-trihydroxy-6,8-dimethyl-3-(3',4'-methylenedioxybenzyl)chroman-4-one (4) and 2,5,7-trihydroxy-6,8-dimethyl-3-(4'-methoxybenzyl)chroman-4-one (5). Their structures have been elucidated by mass and NMR spectroscopy. Compounds 4 and 5 are the first isolated homoisoflavonoids with a hemiacetal function at position 2.
Hoang Anh
Nguyen Thi
NT
Institute of Chemistry, National Centre for Natural Sciences and Technology, Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam.
Van Sung
Tran
T
Porzel
Andrea
A
Franke
Katrin
K
Wessjohann
Ludger A
LA
D000080:Acetals / Q000737:chemistry; D002845:Chromatography / Q000379:methods; D007529:Isoflavones / Q000737:chemistry* / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D031441:Ophiopogon / Q000737:chemistry*; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D000080:Acetals; D007529:Isoflavones