title: Congenital diaphragmatic hernia. Two cases with early prenatal diagnosis and increased nuchal translucency.
abstract: The early ultrasound prenatal diagnosis of congenital diaphragmatic hernia is uncommon and suggests a poor outcome. We report 2 cases diagnosed at 10 and 12 weeks' gestation, with increased fetal nuchal translucency thickness (4 and 11 mm) and associated abnormalities (complex heart defect in one and many malformations in the other, including duodenal atresia and asplenia). In 1 case, the baby was delivered vaginally at 36 weeks, but neonatal death occurred; the pregnancy was terminated at 15 weeks in the second case.
authors.affiliation: Department of Pediatric Surgery, Centre Hospitalier Universitaire, Saint-Etienne, France. mnf.varlet@wanadoo.fr
authors.forename: François
authors.initials: F
authors.lastname: Varlet
authors.forename: Frantz
authors.initials: F
authors.lastname: Bousquet
authors.forename: Alix
authors.initials: A
authors.lastname: Clemenson
authors.forename: Céline
authors.initials: C
authors.lastname: Chauleur
authors.forename: Nathalie
authors.initials: N
authors.lastname: Kopp-Dutour
authors.forename: Mireille
authors.initials: M
authors.lastname: Tronchet
authors.forename: Georges
authors.initials: G
authors.lastname: Teyssier
authors.forename: Fabienne
authors.initials: F
authors.lastname: Prieur
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: Varlet
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D000328:Adult; D004386:Duodenum / Q000002:abnormalities; D017809:Fatal Outcome; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006548:Hernia, Diaphragmatic / Q000000981:diagnostic imaging*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D008297:Male; D011247:Pregnancy; D016216:Ultrasonography, Prenatal