Antidiabetic activity of Terminalia pallida fruit in alloxan induced diabetic rats.
Different doses of ethanolic fraction of fruits of Terminalia pallida were evaluated for hypoglycemic and antihyperglycemic activity in normal and alloxan diabetic rats. The oral administration of ethanolic extract at a dosage of 0.5 g/kg body weight exhibited a significant antihyperglycemic activity in alloxan diabetic rats, whereas in normal rats no hypoglycemic activity was observed.
Kameswara Rao
B
B
Department of Biochemistry, S.V. University, Tirupathi 517502, Andhra Pradesh, India.
Renuka Sudarshan
P
P
Rajasekhar
M D
MD
Nagaraju
N
N
Appa Rao
Ch
Ch
D000284:Administration, Oral; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol; D005638:Fruit; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D029766:Terminalia
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000431:Ethanol