Congenital diaphragmatic hernia. Two cases with early prenatal diagnosis and increased nuchal translucency.
The early ultrasound prenatal diagnosis of congenital diaphragmatic hernia is uncommon and suggests a poor outcome. We report 2 cases diagnosed at 10 and 12 weeks' gestation, with increased fetal nuchal translucency thickness (4 and 11 mm) and associated abnormalities (complex heart defect in one and many malformations in the other, including duodenal atresia and asplenia). In 1 case, the baby was delivered vaginally at 36 weeks, but neonatal death occurred; the pregnancy was terminated at 15 weeks in the second case.
Varlet
François
F
Department of Pediatric Surgery, Centre Hospitalier Universitaire, Saint-Etienne, France. mnf.varlet@wanadoo.fr
Bousquet
Frantz
F
Clemenson
Alix
A
Chauleur
Céline
C
Kopp-Dutour
Nathalie
N
Tronchet
Mireille
M
Teyssier
Georges
G
Prieur
Fabienne
F
Varlet
Marie-Noëlle
MN
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D000328:Adult; D004386:Duodenum / Q000002:abnormalities; D017809:Fatal Outcome; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006548:Hernia, Diaphragmatic / Q000000981:diagnostic imaging*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D008297:Male; D011247:Pregnancy; D016216:Ultrasonography, Prenatal