title: Paroxysmal nocturnal hemoglobinuria arising from Fanconi anemia.
abstract: The progress of a female child with African type Fanconi anemia that evolves in time into paroxysmal nocturnal hemoglobinuria is described. Modern diagnostic methods are used to confirm this process. A discussion of possible mechanisms ensues.
authors.affiliation: University of the Witwatersrand, Chris-Hani-Baragwanath Hospital, Johannesburg, South Africa. sjaspan@iafrica.com
authors.forename: Linda
authors.initials: L
authors.lastname: Wainwright
authors.forename: Robert A
authors.initials: RA
authors.lastname: Brodsky
authors.forename: Linda K
authors.initials: LK
authors.lastname: Erasmus
authors.forename: Stelios
authors.initials: S
authors.lastname: Poyiadjis
authors.forename: Gita
authors.initials: G
authors.lastname: Naidu
authors.forename: Diane
authors.initials: D
authors.lastname: MacKinnon
mesh_terms: D002648:Child; D004912:Erythrocytes / Q000378:metabolism / Q000473:pathology; D005199:Fanconi Anemia / Q000097:blood / Q000150:complications*; D005260:Female; D005434:Flow Cytometry; D006457:Hemoglobinuria, Paroxysmal / Q000097:blood / Q000209:etiology*; D006801:Humans