Pd.Et3B-catalyzed alkylation of amines with allylic alcohols.
A combination of catalytic amounts of Pd (0.05 mmol) and Et3B (0.3 mmol) promotes allylic alkylation of primary and secondary aromatic and aliphatic amines (1.0 mmol) by the direct use of allylic alcohols, providing tertiary amines in excellent yields under mild conditions (room temperature approximately 50 degrees C).
Kimura
Masanari
M
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan. masanari@net.nagasaki-u.ac.jp
Futamata
Makoto
M
Shibata
Kazufumi
K
Tamaru
Yoshinao
Y