[Diagnosis of chronic lymphoid leukemia (an immunomorphological study)].
31 cases of chronic lymphoid leukemia (CLL)/lymphoma from small lymphocytes (LSL) was studied immunomorphologically. All cases had B-phenotype and positive expression of markers CD 5, CD 23. Most characteristic for CLL/LSL was pseudofollicular character of tumour growth. Two morphological variants of CLL/LSL having similar phenotype were distinguished: typical variant with roundish conturs of tumour cells and atypical with centrocytoid morphology of tumour cell nuclei.
Takhaev
Z V
ZV
N. N. Blokhin Cancer Research Centre, 115478, Moscow.
Probatova
N A
NA
Tupitsyn
N N
NN
Sholokhova
E N
EN
Osmanova
D Sh
DSh
D000328:Adult; D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis; D001402:B-Lymphocytes / Q000473:pathology; D018956:CD5 Antigens / Q000032:analysis; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D017455:Receptors, IgE / Q000032:analysis
D000944:Antigens, Differentiation, B-Lymphocyte; D018956:CD5 Antigens; D017455:Receptors, IgE