title: [Study on induction of ginsenosides on HL-60 cell apoptosis].
abstract: OBJECTIVE
  To observe whether the Ginsenosides (GS) could induce HL-60 cell line apoptosis from promyelocytic leukemia.
  
  
  METHODS
  HL-60 cells were treated with GS of various concentration to observe the effect of GS on cell morphological change, the DNA content change by flow cytometry, DNA ladder by electrophoresis, and apoptosis rate by Annexin V-FITC test of the cells.
  
  
  RESULTS
  GS could inhibit the growth of HL-60 cells and induce cell apoptosis in a certain scope of dose and reacting time.
  
  
  CONCLUSIONS
  GS could specifically induce apoptosis in HL-60 cells, which provides an experimental basis for treatment of leukemia with GS as an supplemntary agent of chemotherapy.
authors.affiliation: Institute of Hematopathy, Zhejiang Provincial TCM Hospital, Hangzhou 310006.
authors.forename: Yang-ping
authors.initials: YP
authors.lastname: Niu
authors.forename: Ruilan
authors.initials: R
authors.lastname: Gao
authors.forename: Tao
authors.initials: T
authors.lastname: Helen
mesh_terms: D017209:Apoptosis / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D004273:DNA, Neoplasm / Q000032:analysis; D036145:Ginsenosides / Q000494:pharmacology*; D018922:HL-60 Cells / Q000473:pathology; D006801:Humans
chemical_list: D004273:DNA, Neoplasm; D036145:Ginsenosides