Viral respiratory infections in young children attending day care in urban Northeast Brazil.
A cohort of children attending a day care center in Salvador (Bahia, Brazil) was studied prospectively to determine the incidence of viral respiratory infectious episodes and to identify the viruses associated with them. Two hundred seventy-one nasopharyngeal samples were collected over a 1-year period for examination, using indirect immunofluorescence with monoclonal antibodies against adenovirus, influenza A and B, parainfluenzae 1-3, and respiratory syncytial virus, and reverse transcriptase-polymerase chain reaction for picornavirus. Examination yielded positive results in 116 samples (42.8%). Rhinovirus was identified alone in 56 samples (48.3%) and was observed along with other viruses in 11 additional samples. Incidence density of viral respiratory infectious episodes was 7.66 episodes/1,000 child-days.
Souza
Leda Solano de Freitas
LS
Department of Pediatrics and Department of Preventive Medicine, Faculty of Medicine Federal University of Bahia, Salvador, Bahia, Brazil. ledasolano@bol.com.br
Ramos
Eduardo Antônio Gonçalves
EA
Carvalho
Fernando Martins
FM
Guedes
Virgínia Maria Castro Ribeiro
VM
Souza
Lídia Silva
LS
Rocha
Cristiane Machado
CM
Soares
Andréa Barreto
AB
Velloso
Luciana de Freitas
Lde F
Macedo
Izolete Santos
IS
Moura
Fernanda Edna Araujo
FE
Siqueira
Marilda
M
Fortes
Silvana
S
de Jesus
Cibele Cruz
CC
Santiago
Christiane Maria Gaspar
CM
Carvalho
Ana Maria da Silva
AM
Arruda
Eurico
E
D000208:Acute Disease; D001826:Body Fluids / Q000821:virology; D001938:Brazil / Q000453:epidemiology; D015331:Cohort Studies; D003631:Day Care, Medical; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D015994:Incidence; D010850:Picornaviridae Infections / Q000453:epidemiology; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000821:virology; D012229:Rhinovirus; D012621:Seasons; D014505:Urban Population; D014777:Virus Diseases / Q000453:epidemiology*