[Comparative characteristics of diagnostic methods of primary hyperparathyroidism in patients with urolithiasis].
Nephrolithiasis (NL) is a frequent complication of hyperparathyroidism (HPT). Such patients account for 5% of those with nephrolithogenesis. The study included 89 HPT patients (age 34.8 +/- 1.9 years) with NL, 22 patients (age 38 +/- 1.4 years) with NL and 10 healthy controls (age 30 +/- 1.2 years). Hypercalciemia was seen in 27-20% of patients with HPT and NL, 9-10% of patients with nephrolithiasis. Evaluation of parathyroid hormone (PTH) levels in the blood of the examinees showed its high diagnostic value: in 89% of HPT patients this level was high. It was also elevated in 10% of NL patients. cAMP in HPT and NL was elevated in 68.48 and 12% of patients, respectively, serum concentration of Ca2+ was high in 81.4 and 24.5%, Ca load test was positive in 80.9 and 10% of the patients, respectively. It is important for diagnosis that in HPT bone mass is low.
Ismailov
S I
SI
Uzbekov
K K
KK
Gaĭbullaev
A A
AA
Alimzhanov
N A
NA
Nasirov
A A
AA
Babakhanov
B Kh
BKh
D000293:Adolescent; D000328:Adult; D000368:Aged; D015519:Bone Density; D002118:Calcium / Q000097:blood / Q000652:urine; D000242:Cyclic AMP / Q000097:blood; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis; D006961:Hyperparathyroidism / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000652:urine; D007669:Kidney Calculi / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology* / Q000652:urine; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis / Q000000981:diagnostic imaging; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood / Q000652:urine; D011859:Radiography; D014463:Ultrasonography
D010281:Parathyroid Hormone; D010758:Phosphorus; D000242:Cyclic AMP; D002118:Calcium