[Terbium sensitized chemiluminescence of enoxacin].
OBJECTIVE
To determine the enoxacin by means of terbium sensitized chemiluminescence in pharmaceutical preparations as well as urine samples.


METHODS
Through six-way injection valve Ce4+, H2SO3, Tb3+ and enoxacin (ENX) standard solutions were injected into the flow system in a certain order, the chemiluminescence signal was detected by weak luminescence analyzer.


RESULTS
The chemiluminescence intensity was linearly related to the concentration of ENX in the range of 2.0 x 10(-9)-6.0 x 10(-8) mol.L-1 with a detection limit of 4.0 x 10(-10) mol.L-1. Relative standard deviation was less than 1.6% (n = 11).


CONCLUSIONS
It provides a sensitive rapid, simple and accuracy measurement of enoxacin for the pharmacokinetic studies.
Wang
X
X
Department of Chemistry, Beijing Normal University, Beijing 100875, China.
Zhao
H C
HC
D000890:Anti-Infective Agents / Q000032:analysis* / Q000652:urine; D015365:Enoxacin / Q000032:analysis* / Q000652:urine; D006801:Humans; D008163:Luminescent Measurements; D013607:Tablets / Q000737:chemistry; D013725:Terbium / Q000737:chemistry*
D000890:Anti-Infective Agents; D013607:Tablets; D013725:Terbium; D015365:Enoxacin