[Effect of lycium barbarum L on defending free radicals of mice caused by hypoxia].
The effect of Lycium Barbarum L. (LB) on the free radical defending system during hypoxia was tested. Fifty six mice were divided into 3 groups. Experimental mice were fed with LB and the control mice were fed with distilled water by tube feeding for 16 days. Animals were put into each enclosed bottle for testing the effect of hypoxia. The results showed that LB treatment could not prolong the survival time (P > 0.05), but increase the activities of superoxide dismutase (SOD), catalase(CAT) and total anti-oxidative capacity as compared with the control group(P < 0.05). The study indicated that LB could not increase the hypoxic tolerance, but it might have a protective effect on free radical injury caused by hypoxia.
Li
Guoli
G
Faculty of Preventive Medicine, Ningxia Medicine College, Yinchuan 750004, China.
Yang
Jianjun
J
Ren
Binbin
B
Wang
Zijun
Z
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002374:Catalase / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry; D000860:Hypoxia / Q000201:enzymology*; D032305:Lycium / Q000737:chemistry*; D008297:Male; D051379:Mice; D011897:Random Allocation; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D002374:Catalase; D013482:Superoxide Dismutase