title: Evaluation of hemostasis by the Clot Signature Analyzer: a potentially valuable device for the anesthesiologist.
abstract: Rapid detection of hemostatic defects presents a challenge for the anesthesiologist who must balance anesthetic and surgical considerations for maintaining adequate platelet and coagulant factors, while keeping allogenic blood exposure to a minimum. The Clot Signature Analyzer, a point-of-care device capable of rapid response and easy interpretation is described here. Its applicability in two obstetrical patients with platelet dysfunction is discussed.
authors.affiliation: Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Haddadin
authors.forename: C M
authors.initials: CM
authors.lastname: Ayoub
authors.forename: F B
authors.initials: FB
authors.lastname: Sevarino
authors.forename: C S
authors.initials: CS
authors.lastname: Rinder
mesh_terms: D000328:Adult; D000758:Anesthesia; D001778:Blood Coagulation Disorders / Q000175:diagnosis; D001780:Blood Coagulation Tests / Q000295:instrumentation* / Q000379:methods; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D022861:Hermanski-Pudlak Syndrome / Q000097:blood; D006801:Humans; D007432:Intraoperative Period; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood