Metabotropic glutamate receptors provide intrinsic modulation of the lamprey locomotor network.
Spinal networks generate the motor pattern underlying locomotion. These are subject to modulatory systems that influence their operation and thereby result in a flexible network organization. In this review, we have summarized the mechanisms by which the different metabotropic glutamate receptor subtypes fine-tune the cellular and synaptic properties and thus underlie intrinsic modulation of the activity of the locomotor network in the lamprey.
El Manira
Abdeljabbar
A
Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden. abdel.elmanira@neuro.ki.se
Kettunen
Petronella
P
Hess
Dietmar
D
Krieger
Patrik
P
D000818:Animals; D007798:Lampreys / Q000502:physiology*; D008124:Locomotion / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D018094:Receptors, Metabotropic Glutamate / Q000502:physiology*; D017661:Receptors, Presynaptic / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
D018094:Receptors, Metabotropic Glutamate; D017661:Receptors, Presynaptic