title: [Pathogen variance and drug-sensibility analysis of lower-respiratory-tract bacterial infection in chronic pulmonary heart disease].
abstract: We contrastively analyzed pathogens and their drug sensibilities of lower-respiratory-tract infection in chronic pulmonary heart disease in two different periods. The results were that the Gram-positive cocci (GPC) was 43.8% and Gram-negative bacilli (GNB) was 56.2% in Group A (1985-1990); GPC was 24.6% and GNB was 75.4% in Group B (1995-2000). The predominant bacteria were in the following order: Preudomonas (21.9%), pneumococcal (18.8%), streptococcus (10.9%), acinetobacter (9.4%), staphylococcus epidermidis (7.8%), and klebsiella (7.8%) in Group A; and preudomonas (30.7%), acinetobacter (12.3%), staphylococcus epidermidis (12.3%), klebsiella (10.5%), enteric bacilli (7.0%), and staphylococcus aureus (7.0%) in Group B. The results suggest that GNB is the main pathogen in recent years; sensibility of most drugs in the 1990s fell in varying degrees compared with that in the 1980s, but antibacterial in common use is still available.
authors.affiliation: Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Zhi-yuan
authors.initials: ZY
authors.lastname: Zheng
authors.forename: Bai-ling
authors.initials: BL
authors.lastname: Luo
authors.forename: Qiong
authors.initials: Q
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010406:Penicillins / Q000494:pharmacology; D018410:Pneumonia, Bacterial / Q000150:complications / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D011660:Pulmonary Heart Disease / Q000150:complications*; D013296:Streptococcus pneumoniae / Q000187:drug effects
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D010406:Penicillins