Endoscopic mucosal resection in the management of gastric carcinoid tumors.
OBJECTIVE
Gastric carcinoid tumors are a rare disease. Previously, total gastrectomy was regarded as the treatment of choice. However, differences in biological malignancy have recently led to the increased use of endoscopic mucosal resection (EMR) for treatment. We studied the outcome of EMR in patients with gastric carcinoids who were treated at our hospital and discuss the indications for endoscopic treatment.


METHODS
Between 1986 and 1999 we carried out gastric mucosal resection in five patients with gastric carcinoid tumors. The procedure used for EMR was either strip biopsy or endoscopic aspiration mucosectomy.


RESULTS
The carcinoid tumors measured 10 mm or less in four of the five patients. Two patients had type A gastritis, and all had hypergastrinemia. There was no evidence of recurrence during follow-up (range 6 - 66 months; mean 32.6 months).


CONCLUSIONS
EMR is useful in the management of type 1 gastric carcinoids as classified by Rindi (hypergastrinemia; tumor diameter of 10 mm or less).
Ichikawa
J
J
Gastroenterology Division, Department of Internal Medicine, Kitasato University East Hospital, 2-1-1 Asamizo-dai, Sagamihara-city, Kanagawa-ken 228-8520, Japan. ichikawa-jun@zamaayase.kanagawa.med.or.jp
Tanabe
S
S
Koizumi
W
W
Kida
Y
Y
Imaizumi
H
H
Kida
M
M
Saigenji
K
K
Mitomi
H
H
D000328:Adult; D000368:Aged; D001706:Biopsy; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D004724:Endoscopy; D019160:Endosonography; D005260:Female; D005753:Gastric Mucosa / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007413:Intestinal Mucosa / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013396:Suction