title: Minimally invasive techniques for management of early glottic cancer.
abstract: This article reviews management of early laryngeal squamous cell carcinoma with respect to current standards of practice and recent advances in minimally invasive endoscopic surgery, specifically highlighting powered instrumentation as an alternative to transoral laser resection of early glottic lesions. Limitations of the current staging system, controversy regarding management of lesions involving the anterior commissure, and the role of radiation therapy versus surgical management are also discussed with reference to current outcomes literature.
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery and Anesthesiology and Critical Care Medicine, Johns Hopkins Outpatient Center, 601 N. Caroline Street, Baltimore, MD 21287, USA. pflint@jhmi.edu
authors.forename: Paul W
authors.initials: PW
authors.lastname: Flint
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D007822:Laryngeal Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D007828:Laryngoscopy / Q000379:methods; D053685:Laser Therapy / Q000379:methods*; D019656:Loss of Heterozygosity / Q000235:genetics; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009367:Neoplasm Staging; D018579:Patient Selection; D016896:Treatment Outcome
chemical_list: D005819:Genetic Markers