title: Synthesis, catalytic properties and biological activity of new water soluble ruthenium cyclopentadienyl PTA complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane).
abstract: The new water soluble ruthenium complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane) were synthesised and characterised. Their evaluation as regioselective catalysts for hydrogenation of unsaturated ketones in aqueous biphasic conditions and as cytotoxic agents towards the TS/A adenocarcinoma cell line is briefly presented.
authors.affiliation: Istituto di Chimica dei Composti Organometallici, ICCOM-CNR, Via Jacopo Nardi 39, 50132 Firenze, Italy.
authors.forename: Dina N
authors.initials: DN
authors.lastname: Akbayeva
authors.forename: Luca
authors.initials: L
authors.lastname: Gonsalvi
authors.forename: Werner
authors.initials: W
authors.lastname: Oberhauser
authors.forename: Maurizio
authors.initials: M
authors.lastname: Peruzzini
authors.forename: Francesco
authors.initials: F
authors.lastname: Vizza
authors.forename: Peter
authors.initials: P
authors.lastname: Brüggeller
authors.forename: Antonio
authors.initials: A
authors.lastname: Romerosa
authors.forename: Gianni
authors.initials: G
authors.lastname: Sava
authors.forename: Alberta
authors.initials: A
authors.lastname: Bergamo
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002384:Catalysis; D002455:Cell Division / Q000187:drug effects; D006865:Hydrogenation; D051379:Mice; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D012428:Ruthenium / Q000737:chemistry* / Q000494:pharmacology; D012995:Solubility; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D009942:Organometallic Compounds; D012428:Ruthenium