title: Ring-enhanced mass in the brain of a woman with systemic lupus erythematosus and elevated serum CA19-9 level: brain abscess or metastatic tumor?--case report.
abstract: A 70-year-old woman with systemic lupus erythematosus presented with a brain abscess manifesting as progressive monoparesis of the right lower extremity over 4 days. She had had no episodes of fever, and did not complain of headache or exhibit any signs of meningeal irritability. Computed tomography of the brain showed a round, low-density mass with strong ring enhancement in the left frontal lobe. Laboratory examination found a moderately elevated serum level of CA19-9, a marker of some digestive organ cancers. Together with the absence of febrile episodes, headache, and a rise in leukocyte count, the initial suspicion was metastatic brain tumor rather than brain abscess. However, diffusion-weighted magnetic resonance imaging depicted the mass as a very hyperintense area. The neuroimaging diagnosis was brain abscess. After conservative treatment with intravenous antibiotics for 6 weeks, the brain abscess completely resolved, and the patient was discharged without neurological deficits.
authors.affiliation: Department of Neurosurgery, National Tokyo Medical Center, Tokyo, Japan. GInamasu@aol.com
authors.forename: Joji
authors.initials: J
authors.lastname: Inamasu
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Saito
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kuroshima
authors.forename: Keita
authors.initials: K
authors.lastname: Mayanagi
authors.forename: Shigeo
authors.initials: S
authors.lastname: Ohba
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nishikai
authors.forename: Kazunori
authors.initials: K
authors.lastname: Koyama
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Ichikizaki
mesh_terms: D000368:Aged; D001922:Brain Abscess / Q000097:blood / Q000175:diagnosis*; D001932:Brain Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000556:secondary*; D018395:CA-19-9 Antigen / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood*
chemical_list: D018395:CA-19-9 Antigen