title: Outbreak of clostridial myocarditis in calves.
abstract: This paper describes the epidemiological and pathological features of an outbreak of clostridial myocarditis in calves due to Clostridium chauvoei. Four of seven two-month-old Hereford calves died in the course of a week. Their gross postmortem lesions were similar and consisted of irregular dark red areas of myocardial necrosis through the full thickness of the atrial and ventricular myocardium. No lesions were observed in skeletal muscle. The heart muscle had extensive multifocal areas of acute coagulative necrosis. The diagnosis was confirmed by a fluorescent antibody technique on tissue smears, by a streptavidin-biotin technique on formalin-fixed, paraffin-embedded tissues, and by a PCR technique specific for the 16S rRNA of C. chauvoei.
authors.affiliation: Animal Health Unit, National Institute of Agricultural Technology, CC277, (8400) Bariloche, Argentina.
authors.forename: F A
authors.initials: FA
authors.lastname: Uzal
authors.forename: M
authors.initials: M
authors.lastname: Paramidani
authors.forename: R
authors.initials: R
authors.lastname: Assis
authors.forename: W
authors.initials: W
authors.lastname: Morris
authors.forename: M F
authors.initials: MF
authors.lastname: Miyakawa
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001344:Autopsy / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D003013:Clostridium / Q000302:isolation & purification / Q000472:pathogenicity*; D003015:Clostridium Infections / Q000453:epidemiology / Q000662:veterinary*; D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks / Q000662:veterinary*; D009205:Myocarditis / Q000453:epidemiology / Q000662:veterinary*; D009336:Necrosis; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000032:analysis
chemical_list: D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S