Improved systemic ventricular function after carvedilol administration in a patient with congenitally corrected transposition of the great arteries.
Congenitally corrected transposition of the great arteries (CCTGA) is associated with shortened survival due, at least in part, to progressive systolic dysfunction of the systemic ventricle. We report a substantial improvement in systemic ventricular function with carvedilol in a 63-year-old man with CCTGA.
Lindenfeld
JoAnn
J
Division of Cardiology, University of Colorado Hospital and Children's Hospital, University of Colorado Health Sciences Center, Denver, Colorado, USA. joAnn.lindenfield@uchsc.edu
Keller
Karin
K
Campbell
David N
DN
Wolfe
Robert R
RR
Quaife
Robert A
RA
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D000077261:Carvedilol; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D013318:Stroke Volume / Q000187:drug effects / Q000502:physiology; D014188:Transposition of Great Vessels / Q000188:drug therapy / Q000503:physiopathology*; D018754:Ventricular Dysfunction / Q000188:drug therapy* / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol