[Gene frequencies of 4 STR loci in Tibetan population of Yunnan province].
OBJECTIVE
To investigate the gene frequencies of 4 STR loci in Tibetan population of Yunnan.


METHODS
Multiple polymerase chain reaction (PCR), denaturing polyacrylamide gel electrophoresis and silver staining were used to detect D21S11, D8S1179, D16S539 and LPL loci. DNA samples collected from 105 unrelated Tibetan individuals in Yunnan province were analyzed.


RESULTS
At D21S11, D8S1179, D16S539 and LPL loci, 13, 8, 7, 6 alleles and 33, 21, 16 and 9 genotypes were observed, respectively. The genotype distribution of the 4 STR was in accordance with the Hardy-Weinberg equilibrium.


CONCLUSIONS
The high combined discrimination power and exclusion power of the four loci in Tibetan population make multi-PCR detection a valuable tool for forensic identity, genetics and anthropology.
Cheng
Bao-wen
BW
Yuxi Public Security Bureau of Yunnan Province, Yuxi, PR China.
Xiao
Chun-jie
CJ
D000483:Alleles; D002681:China; D004247:DNA / Q000235:genetics; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D008071:Lipoprotein Lipase / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D020080:Tandem Repeat Sequences / Q000235:genetics*; D018609:Tibet / Q000208:ethnology
D004247:DNA; D008071:Lipoprotein Lipase