[Low conductivity cationic channel in intact endothelium of the rat aorta].
A new low-conductance cationic channel has been recorded with the patch-clamp technique in excised patches of the luminal membrane of intact endothelial cells. The channel had conductance of 5.4 pS and the lifetime of 46 ms. It was equally permeable for Na+ and K+, but impermeable to Cl-. The lifetime and probability of the open state of the channel were independent of the membrane potential.
Marchenko
S M
SM
A.A. Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kiev.
D000818:Animals; D001013:Aorta, Thoracic / Q000502:physiology*; D002412:Cations / Q000378:metabolism*; D002462:Cell Membrane / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology*; D066298:In Vitro Techniques; D015640:Ion Channel Gating / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D018408:Patch-Clamp Techniques; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000378:metabolism
D002412:Cations; D007473:Ion Channels; D012964:Sodium; D011188:Potassium