Neurotransmission of cognition, part 1, Dopamine is a hitchhiker in frontal cortex: norepinephrine transporters regulate dopamine.
Since the frontal cortex has a low density of dopamine transporters, dopamine has to be inactivated there by hitching a ride on the norepinephrine transporter of neighboring norepinephrine neurons.
Stahl
Stephen M
SM
Neuroscience Education Institute, Carlsbad, California 92009, USA.
D001921:Brain / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D004298:Dopamine / Q000378:metabolism / Q000502:physiology*; D005625:Frontal Lobe / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D009474:Neurons / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology; D050484:Norepinephrine Plasma Membrane Transport Proteins; D027981:Symporters / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
D050484:Norepinephrine Plasma Membrane Transport Proteins; C493227:SLC6A2 protein, human; D027981:Symporters; D004298:Dopamine; D009638:Norepinephrine