Determination of perfluorooctane sulfonate in river water by liquid chromatography/atmospheric pressure photoionization mass spectrometry by automated on-line extraction using turbulent flow chromatography.
A simple, fast and sensitive liquid chromatography/atmospheric pressure photoionization mass spectrometry (LC/APPI-MS) method, with automated on-line extraction using turbulent flow chromatography (TFC), was developed for the determination of perfluorooctane sulfonate (PFOS) in river water. In this method, following an on-line extraction by injection onto a column under TFC conditions, PFOS is back-flushed onto a reversed-phase column via on-line column switching, and resolved chromatographically at a laminar flow rate of 1 mL min(-1). Using this tandem LC-LC/APPI-MS system the extraction, separation and selective detection of PFOS in river water could be achieved with satisfactory selectivity and sensitivity. The limit of detection (LOD) (S/N = 3) and the limit of quantitation (LOQ) (S/N = 10)were 5.35 and 17.86 pg mL(-1). The described procedure was very simple since no off-line sample preparation was required, total analysis time being 18.75 min.
Takino
Masahiko
M
Kansai Branch Office, Yokogawa Analytical Systems Inc., Yodogawa, Osaka, Japan. masahiko_takino@agilent.com
Daishima
Shigeki
S
Nakahara
Taketoshi
T
D017738:Alkanesulfonic Acids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005466:Fluorocarbons / Q000032:analysis*; D005618:Fresh Water / Q000737:chemistry*; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization; D014873:Water Pollutants / Q000032:analysis*
D017738:Alkanesulfonic Acids; D005466:Fluorocarbons; D014873:Water Pollutants; C076994:perfluorooctane sulfonic acid