A new crystal form of nateglinide.
OBJECTIVE
To find a new crystal structure of S-form in nateglinide [N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine]. The XRD, IR patterns and data were given and the melting point was determined.


METHODS
Phase analysis was performed by X-ray powder diffraction, IR and elemental analysis and the melting point was determined by differential scan calorimetry.


RESULTS
S-form nateglinide is different from H-form or B-form. The melting point is 172.04 degrees C.


CONCLUSIONS
The S-form nateglinide is a new crystal form.
Li
G
G
Chemistry and Physics Centralaboratory, Nanjing Normal University, Nanjing 210097, China. ligang-1959@263.net
Su
G Q
GQ
Xu
Q W
QW
Zhu
C Q
CQ
D003460:Crystallization; D018360:Crystallography, X-Ray; D003510:Cyclohexanes / Q000737:chemistry*; D007004:Hypoglycemic Agents / Q000737:chemistry*; D000077715:Nateglinide; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry*; D033362:Powder Diffraction; D017550:Spectroscopy, Fourier Transform Infrared
D003510:Cyclohexanes; D007004:Hypoglycemic Agents; D000077715:Nateglinide; D010649:Phenylalanine