A case of acute pneumonitis induced by injection of silicone for colpoplasty.
Silicone fluid (polymethylsiloxane) is a liquid polymer that had been widely used in breast augmentation and other cosmetic procedures. However, many adverse reactions after silicone injections into human beings have been reported including adverse pulmonary sequelae. We report a case of a 46-year-old woman who suffered from acute pneumonitis that was induced by illicit injection of silicone into the vaginal wall for colpoplasty. The pulmonary involvement was documented by transbronchial lung biopsy and bronchoalveolar lavage where examination with the electron microscope disclosed the presence of large quantities of pleomorphic cytoplasmic inclusions in alveolar macrophages. Clinicians should be aware of this unusual complication of injection of silicone.
Kim
Cheol Hyeon
CH
Department of Internal Medicine, Seoul National University College of Medicine and Lung Institute, Medical Research Center, Seoul National University, Seoul, Korea.
Chung
Doo Hyun
DH
Yoo
Chul-Gyu
CG
Lee
Choon-Taek
CT
Han
Sung Koo
SK
Shim
Young-Soo
YS
Kim
Young Whan
YW
D000208:Acute Disease; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D005260:Female; D005782:Gels / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced*; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*; D014621:Vagina / Q000601:surgery
D005782:Gels; D012828:Silicones; C078211:polymethylsiloxane