A high-protein diet enhances satiety without conditioned taste aversion in the rat.
In order to determine the respective roles of conditioned food aversion, satiety and palatability, we studied behavioral responses to a 50% total milk protein diet, compared with those to a normal protein diet containing 14% total milk protein. Different paradigms were employed, including meal pattern analysis, two-choice testing, flavor testing, a behavioral satiety sequence (BSS) and taste reactivity. Our experiments showed that only behavioral and food intake parameters were disturbed during the first day when an animal ate the high-protein (P50) diet, and that most parameters returned to baseline values as soon as the second day of P50. Rats adapted to P50 did not acquire a conditioned taste aversion (CTA) but exhibited satiety, and a normal BSS. The initial reduction in high-protein diet intake appeared to result from the lower palatability of the food combined with the satiety effect of the high-protein diet and the delay required for metabolic adaptation to the higher protein level.
Bensaïd
Ahmed
A
Institut National de la Recherche Agronomique, Unité INRA-INAPG de Physiologie de la Nutrition et du Comportement Alimentaire, Institut National Agronomique Paris-Grignon, 16 rue Claude Bernard, F75231 Paris Cedex 05, France.
Tomé
Daniel
D
L'Heureux-Bourdon
Diane
D
Even
Patrick
P
Gietzen
Dorothy
D
Morens
Céline
C
Gaudichon
Claire
C
Larue-Achagiotis
Christiane
C
Fromentin
Gilles
G
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development / Q000523:psychology; D001362:Avoidance Learning; D001522:Behavior, Animal / Q000187:drug effects; D002755:Choice Behavior; D003213:Conditioning, Psychological; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior / Q000187:drug effects; D005518:Food Preferences; D006120:Grooming; D008297:Male; D008894:Milk Proteins / Q000008:administration & dosage*; D009043:Motor Activity; D051381:Rats; D017208:Rats, Wistar; D012146:Rest; D012528:Satiety Response / Q000187:drug effects*; D013649:Taste
D008894:Milk Proteins