[Gene polymorphisms in Uighur patients with Abnormal Savda].
OBJECTIVE
To investigate gene polymorphisms in Uighur patients with Abnormal Savda.


METHODS
Polymorphisms of genomic fingerprints generated by arbitrarily primed PCR(AP-PCR) can be used for distinguishing between strains of almost any organism. The authors of this article applied the technique to the polymorphism analysis on the DNA of Uighur patients suffering from four kinds of Abnormal Savda (n=116), and on the DNA of a control group(n=50).


RESULTS
From the patients, 42 fragments were obtained, among them 27(64.2%) fragments did not show gene polymorphisms. On the 220-344 bp regions, the authors detected 6 AP-PCR products showing individual specificity.


CONCLUSIONS
The polymorphisms may serve as a molecular marker for gene diagnosis in the patients with Abnormal Savda.
Halmurat
Upur
U
Institute of Xinjiang Uighur Medicine, Urumqi, Xinjiang, PR China.
Askar
Yimit
Y
Ilhamjan
Sabit
S
Obul
Kasim
K
Roxangul
Sabir
S
D001249:Asthma / Q000175:diagnosis / Q000235:genetics; D004247:DNA / Q000235:genetics*; D016172:DNA Fingerprinting; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000235:genetics; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic
D005819:Genetic Markers; D004247:DNA