title: Efficient model-based quantification of left ventricular function in 3-D echocardiography.
abstract: Quantitative functional analysis of the left ventricle plays a very important role in the diagnosis of heart diseases. While in standard two-dimensional echocardiography this quantification is limited to rather crude volume estimation, three-dimensional (3-D) echocardiography not only significantly improves its accuracy but also makes it possible to derive valuable additional information, like various wall-motion measurements. In this paper, we present a new efficient method for the functional evaluation of the left ventricle from 3-D echographic sequences. It comprises a segmentation step that is based on the integration of 3-D deformable surfaces and a four-dimensional statistical heart motion model. The segmentation results in an accurate 3-D + time left ventricle discrete representation. Functional descriptors like local wall-motion indexes are automatically derived from this representation. The method has been successfully tested both on electrocardiography-gated and real-time 3-D data. It has proven to be fast, accurate, and robust.
authors.affiliation: Medisys Group, Philips Research France, 51 rue Carnot, 92156 Suresnes, France. Olivier.Gerard@philips.com
authors.forename: Olivier
authors.initials: O
authors.lastname: Gérard
authors.forename: Antoine Collet
authors.initials: AC
authors.lastname: Billon
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Rouet
authors.forename: Marie
authors.initials: M
authors.lastname: Jacob
authors.forename: Maxim
authors.initials: M
authors.lastname: Fradkin
authors.forename: Cyril
authors.initials: C
authors.lastname: Allouche
mesh_terms: D019560:Echocardiography, Three-Dimensional; D004562:Electrocardiography; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D016277:Ventricular Function, Left