title: Metabotropic glutamate receptors provide intrinsic modulation of the lamprey locomotor network.
abstract: Spinal networks generate the motor pattern underlying locomotion. These are subject to modulatory systems that influence their operation and thereby result in a flexible network organization. In this review, we have summarized the mechanisms by which the different metabotropic glutamate receptor subtypes fine-tune the cellular and synaptic properties and thus underlie intrinsic modulation of the activity of the locomotor network in the lamprey.
authors.affiliation: Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden. abdel.elmanira@neuro.ki.se
authors.forename: Abdeljabbar
authors.initials: A
authors.lastname: El Manira
authors.forename: Petronella
authors.initials: P
authors.lastname: Kettunen
authors.forename: Dietmar
authors.initials: D
authors.lastname: Hess
authors.forename: Patrik
authors.initials: P
authors.lastname: Krieger
mesh_terms: D000818:Animals; D007798:Lampreys / Q000502:physiology*; D008124:Locomotion / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D018094:Receptors, Metabotropic Glutamate / Q000502:physiology*; D017661:Receptors, Presynaptic / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D018094:Receptors, Metabotropic Glutamate; D017661:Receptors, Presynaptic