title: Chemical constituents from the Hydrangea chinensis.
abstract: Two quinazolone alkaloids, (+)-febrifugine (1) and isofebrifugine (2), along with three coumarin derivatives, 6-hydroxy coumarin (3), skimmin (5), and umbelliferone-7-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranoside (6), were isolated from the roots of Hydrangea chinensis. Compound 6 is a new compound. In addition, umbelliferone (4), linoleic acid (7), two steroidal glycosides (8, 9), three furfural derivatives (10-12), and butyl-beta-D-fructofuranoside (13) were isolated from the leaves of the same plant. The structures of all isolates were elucidated by spectral methods.
authors.affiliation: Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
authors.forename: Ashraf Taha
authors.initials: AT
authors.lastname: Khalil
authors.forename: Fang-Rong
authors.initials: FR
authors.lastname: Chang
authors.forename: Yue-Han
authors.initials: YH
authors.lastname: Lee
authors.forename: Chung-Yi
authors.initials: CY
authors.lastname: Chen
authors.forename: Chih-Chuang
authors.initials: CC
authors.lastname: Liaw
authors.forename: Patnam
authors.initials: P
authors.lastname: Ramesh
authors.forename: Shyng-Shiou F
authors.initials: SS
authors.lastname: Yuan
authors.forename: Yang-Chang
authors.initials: YC
authors.lastname: Wu
mesh_terms: D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D031966:Hydrangea / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D011799:Quinazolines / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D003374:Coumarins; D010936:Plant Extracts; D011799:Quinazolines; C030123:coumarin