Chiral reagents for the determination of enantiomeric excess and absolute configuration using NMR spectroscopy.
Recent advances in the development of chiral derivatizing and solvating agents that facilitate the determination of enantiomeric excess and absolute configuration are reviewed. These include metal-containing species, host-guest systems, donor-acceptor compounds, and liquid crystal discriminating agents. In the aggregate, these reagents can be used to analyze a wide range of compound classes.
Wenzel
Thomas J
TJ
Department of Chemistry, Bates College, Lewiston, Maine, USA. Twenzel@bates.edu
Wilcox
James D
JD