title: Pulmonary lymphomatoid granulomatosis evolving to large cell lymphoma in the skin.
abstract: Lymphomatoid granulomatosis is an angiodestructive, angioinvasive lymphoproliferative disorder. It involves most frequently lungs, central nervous system and skin. Recent studies indicate that lymphomatoid granulomatosis is an Epstein-Barr virus associated B cell disorder with a background of reactive T lymphocytes. In a 49 year old woman presenting with fever, malaise and pulmonary masses the diagnosis of lymphomatoid granulomatosis was established histologically by open lung biopsy. Following the initial diagnosis the patient was found to have gastric and skin involvement. The skin lesion was diagnosed as diffuse large B-cell lymphoma.
authors.affiliation: Department of Pathology, Adnan Menderes University, Faculty of Medicine, Aydin, 09100, Turkey. nculhaci@hotmail.com
authors.forename: Nil
authors.initials: N
authors.lastname: Culhaci
authors.forename: Edi
authors.initials: E
authors.lastname: Levi
authors.forename: Serdar
authors.initials: S
authors.lastname: Sen
authors.forename: Furuzan
authors.initials: F
authors.lastname: Kacar
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Meteoglu
mesh_terms: D001402:B-Lymphocytes / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D016246:Lymphocytes, Tumor-Infiltrating / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000276:immunology / Q000473:pathology*; D008230:Lymphomatoid Granulomatosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*; D014057:Tomography, X-Ray Computed