Naturally occurring peroxides with biological activities.
New natural peroxides that have potent biological activities with novel diverse structures are reviewed with classification as secondary metabolites such as terpenes, polyketides, phenolics, and hydroperoxides. These compounds, isolated mainly from medicinal plants and marine sponges, are valuable sources in the drug discovery for particularly antitumor and antimalarial agents.
Jung
Mankil
M
Department of Chemistry, Yonsei University, Seoul 120-749, Korea. mkjung@alchemy.yonsei.ac.kr
Kim
Hanjo
H
Lee
Kyunghoon
K
Park
Moonsoo
M
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D000962:Antimalarials / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry* / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008386:Marine Biology; D010545:Peroxides / Q000737:chemistry* / Q000494:pharmacology*; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D011161:Porifera / Q000737:chemistry; D013237:Stereoisomerism; D013729:Terpenes / Q000737:chemistry / Q000494:pharmacology
D000935:Antifungal Agents; D000962:Antimalarials; D000970:Antineoplastic Agents; D001688:Biological Products; D004791:Enzyme Inhibitors; D010545:Peroxides; D010636:Phenols; D013729:Terpenes