title: Neuroblastoma, apoptosis, and growth factors.
abstract: Neuroblastoma is the most common extracranial tumor of childhood. This tumor is associated with alterations in apoptosis and is affected by various growth factors and cytokines. In this short review we will discuss recent findings in our laboratory where we have been studying a cell culture model of neuroblastoma.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, University of Florida, P.O. Box 100286, JHMHSC, Gainesville, Florida 32610-0286, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Beierle
authors.forename: Wei
authors.initials: W
authors.lastname: Dai
authors.forename: Max R
authors.initials: MR
authors.lastname: Langham
authors.forename: Mike K
authors.initials: MK
authors.lastname: Chen
mesh_terms: D017209:Apoptosis / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D002460:Cell Line; D018920:Coculture Techniques; D017077:Culture Media, Conditioned; D016228:Endothelial Growth Factors / Q000378:metabolism / Q000502:physiology*; D022781:Hepatocytes / Q000502:physiology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism / Q000502:physiology*; D008222:Lymphokines / Q000378:metabolism / Q000502:physiology*; D009447:Neuroblastoma / Q000503:physiopathology* / Q000556:secondary; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D040262:Receptors, Vascular Endothelial Growth Factor / Q000378:metabolism; D014407:Tumor Cells, Cultured; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
chemical_list: D017077:Culture Media, Conditioned; D016228:Endothelial Growth Factors; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D019253:Proto-Oncogene Proteins c-bcl-2; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D040262:Receptors, Vascular Endothelial Growth Factor