[Pharmacological studies of trilex on treatment of pharyngitis].
Trilex consisted of three species: Ilex latifolia, Ilex asprella and Ilex rotunda. Trilex had the antipyretic effects, decreased the rat body temperature about 0.8 degree C on yeast induced hyperthermia. Trilex could obviously enhance the threshold of hot plate induced pain in mice. The maximum threshold increased 43.8%. Trilex could also inhibit acetic acid induced inflammatory ooze in mice abdominal cavity. The inhibitory rate was 34.8%. These results showed that trilex had antipyretic, analgesic and anti-inflammatory effects. It could be used to treat acute and chromic pharyngitis.
Jiang
J
J
Department of Pharmcy, Zhongshan University, Guangzhou 510275.
Xu
S
S
Kong
Y
Y
D000700:Analgesics / Q000494:pharmacology*; D018712:Analgesics, Non-Narcotic / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology*; D002199:Capillary Permeability / Q000187:drug effects; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D030017:Ilex / Q000737:chemistry / Q000145:classification; D008297:Male; D051379:Mice; D017288:Pain Threshold / Q000187:drug effects*; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal