Invasion of skin by schistosome cercariae: some neglected facts.
The process of skin invasion by Schistosoma cercariae was reviewed in a recent Trends Research Update, accompanied by a computer animation. Some aspects of that article were misleading and perpetuated misconceptions about parasite migration through the skin that should by now have been dispelled. This article sets out a different interpretation of events, taking account of the extensive data on migration and larval structural changes that have been documented for Schistosoma mansoni over the past 20 years.
Curwen
Rachel S
RS
Department of Biology, Area 5, PO Box 373, University of York, York, UK YO10 5YW. rsc105@york.ac.uk
Wilson
R Alan
RA
D000222:Adaptation, Physiological; D000818:Animals; D006790:Host-Parasite Interactions; D006801:Humans; D010196:Pancreatic Elastase / Q000378:metabolism; D012547:Schistosoma / Q000201:enzymology / Q000254:growth & development / Q000502:physiology*; D012552:Schistosomiasis / Q000469:parasitology*; D012867:Skin / Q000469:parasitology*; D012876:Skin Diseases, Parasitic / Q000469:parasitology
D010196:Pancreatic Elastase