Inflammation and Alzheimer's disease.
Alzheimer's disease (AD) is classified mainly as a neurodegenerative disease. Recent research, however, has shown that inflammatory mechanisms are also associated with AD and that they could have a role in contributing to the pathogenesis of this disease. The evidence is based on histopathological brain studies, laboratory studies of peripheral inflammation and the fact that certain anti-inflammatory drugs could modify the course of AD. There is wide scope for further research using anti-inflammatory therapies in the prevention/treatment of AD, thereby reducing the burden of this widely prevalent condition in the community.
Gupta
A
A
University Department of Geriatric Medicine, Llandough Hospital, Penarth, Glamorgan, UK.
Pansari
K
K
D000544:Alzheimer Disease / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003167:Complement Activation; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000473:pathology*
D000893:Anti-Inflammatory Agents