Microcephaly with plate-like cortical calcification.
Congenital malformations of the central nervous system have varied presentations depending on the stage of embryological development when the insult occurred. We report a neonate with microcephaly associated with plate-like cortical calcification, probably secondary to an unidentified insult at around 11-12 weeks post-conceptional age causing an arrest of the proliferative phase. The associated vasculopathy probably caused diffuse cortical calcification.
Kalyanasundaram
Sridhar
S
Department of Pediatrics, Post Graduate Institute of Medical Education and Research, 160012, Chandigarh, India.
Dutta
Sourabh
S
Narang
Anil
A
Katariya
Sudha
S
D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis; D002114:Calcinosis / Q000150:complications* / Q000175:diagnosis; D002540:Cerebral Cortex; D014695:Cerebral Ventriculography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008831:Microcephaly / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed