[The Gene Chip Technology and the Prospects of Its Application in Hematology and Oncology]
The basic principle, technological procedure and types of gene chips were introduced in the article. The probe choice in practical application and processing and hybridization of detected samples were described. Some researchers have used gene chips in hematology, oncology and cellular differentiation. Gene chips can be used to detect the expression of oncogenes, tumor suppression genes, and cell differentiation- and apoptosis-related genes. It can also help us to further study the association between the polymorphism of human genes and disease susceptibility. The aspects of development and problems in gene chips study were discussed.
Zhang
Xin
X
First Hospital of Beijing Medical University, Beijing 100034, China.
Zhu
Ping
P