title: Peptide derivatives as agonists or antagonists of formylpeptide receptors: analysis of their effects on neutrophils.
abstract: The effects of peptide derivatives as agonists or antagonists of formylpeptide receptors are described, taking into account the related cellular responses by neutrophils. These effects are related to the structure of peptide derivatives, some of which are potent anti HIV-1 agents. Finally, formylpeptide receptor models are depicted.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Via Fossato di Mortara 19, 44100 Ferrara, Italy. dla@dns.unife.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Dalpiaz
authors.forename: Angelo
authors.initials: A
authors.lastname: Scatturin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D019380:Anti-HIV Agents / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009504:Neutrophils / Q000187:drug effects*; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology*; D044042:Receptors, Formyl Peptide; D011971:Receptors, Immunologic / Q000819:agonists* / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D018000:Receptors, Peptide / Q000819:agonists* / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism
chemical_list: D019380:Anti-HIV Agents; D010455:Peptides; D044042:Receptors, Formyl Peptide; D011971:Receptors, Immunologic; D018000:Receptors, Peptide