Cimetidine therapy for epidermodysplasia verruciformis.
A 16-year-old boy with an 8-year history of multiple slightly keratotic papules on his face, trunk, and limbs, is described. On the basis of clinical features, histologic examination of 2 lesions and positivity for HPV 5, a diagnosis of epidermodysplasia verruciformis was made. Treatment with oral cimetidine (40 mg/kg per day) induced a marked improvement after 3 months of therapy, with no relapse at a 6-month follow-up.
Micali
Giuseppe
G
Dermatology Clinic, University of Catania, Catania, Italy. cldermct@dimtel.nti.it
Nasca
Maria Rita
MR
Dall'Oglio
Federica
F
Musumeci
Maria Letizia
ML
D000293:Adolescent; D002927:Cimetidine / Q000627:therapeutic use*; D004819:Epidermodysplasia Verruciformis / Q000188:drug therapy* / Q000473:pathology; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D006635:Histamine H2 Antagonists; D002927:Cimetidine