[Clinical and experimental study on treatment of infantile mycotic enteritis by jiechang mixture].
OBJECTIVE
To evaluate the therapeutic effect and mechanism of Jiechang Mixture (JCM) in treating infantile mycotic enteritis.


METHODS
The children patients confirmed to be suffered from mycotic enteritis were divided randomly into two groups: the 40 cases in the treated group treated with JCM and the 20 cases in the control group treated with fungicidin. The time of stool forming, diarrhea relieving and fungi vanishing were observed. The promoting effect of JCM on small intestine motility and the inhibition of JCM on Candida albicans in stool culture were studied experimentally.


RESULTS
The time of stool forming, diarrhea relieving and fungi vanishing in the treated group were significantly shorter than those in the control group (P < 0.01), and JCM also showed a better effect in improving clinical symptoms and signs of patients than the control. Results of experimental study showed that JCM could abate the ink evacuation of small intestine in mice. The fungi inhibitory test suggested that Candida albicans was susceptible to JCM.


CONCLUSIONS
JCM is an effective herbal medicine in treating infantile mycotic enteritis.
Dong
Y
Y
Ningbo Municipal Hospital of TCM, Zhejiang 315010.
Wang
B C
BC
Zhang
Y X
YX
D000285:Administration, Rectal; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage*; D002177:Candidiasis / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D004751:Enteritis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D051379:Mice; D009761:Nystatin / Q000008:administration & dosage; D008517:Phytotherapy; D011446:Prospective Studies
D000935:Antifungal Agents; D004365:Drugs, Chinese Herbal; D009761:Nystatin