[Establishment of a rabbit model of Acanthamoeba keratitis].
OBJECTIVE
To establish an animal model of Acanthamoeba keratitis.


METHODS
Six New Zealand white rabbits were each injected intrastromally with Acanthamoeba suspension 3 days after subconjunctival injection with dexamethasone.


RESULTS
All of the 6 rabbits developed keratitis. Acanthamoeba protozoa were identified by the methods of corneal scraping with 10% potassium hydroxide wet mount examined under microscope, corneal protozoa culture and pathological section examination.


CONCLUSIONS
A rabbit model of Acanthamoeba keratitis was established.
Deng
X
X
Henan Institute of Ophthalmology, Zhengzhou 450003.
Guo
X
X
Pang
G
G
Tian
X
X
D015823:Acanthamoeba Keratitis / Q000473:pathology / Q000503:physiopathology*; D000818:Animals; D004195:Disease Models, Animal; D007634:Keratitis / Q000473:pathology / Q000503:physiopathology*; D011817:Rabbits; D012106:Research