title: Short and long term mortality associated with foodborne bacterial gastrointestinal infections: registry based study.
abstract: OBJECTIVE
  To determine the excess mortality associated with infections with Salmonella, Campylobacter, Yersinia enterocolitica, and Shigella and to examine the effect of pre-existing illness.
  
  
  METHODS
  Registry based, matched cohort study.
  
  
  METHODS
  Denmark.
  
  
  METHODS
  48 857 people with gastrointestinal infections plus 487 138 controls from the general population.
  
  
  METHODS
  One year mortality among patients with gastrointestinal infections compared with controls after adjustment for comorbidity.
  
  
  RESULTS
  1071 (2.2%) people with gastrointestinal infections died within one year after infection compared with 3636 (0.7%) controls. The relative mortality within one year was 3.1 times higher in patients than in controls. The relative mortality within 30 days of infection was high in all four bacterial groups. Furthermore, there was excess mortality one to six months after infection with Yersinia enterocolitica (relative risk 2.53, 95% confidence interval 1.38 to 4.62) and from six months to one year after infection with Campylobacter (1.35, 1.02 to 1.80) and Salmonella (1.53, 1.31 to 1.79).
  
  
  CONCLUSIONS
  Infections with all these bacteria were associated with an increased short term risk of death, even after pre-existing illnesses were taken into account. Salmonella, Campylobacter, and Yersinia enterocolitica infections were also associated with increased long term mortality.
authors.affiliation: Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK-2300 Copenhagen S, Denmark.
authors.forename: Morten
authors.initials: M
authors.lastname: Helms
authors.forename: Pernille
authors.initials: P
authors.lastname: Vastrup
authors.forename: Peter
authors.initials: P
authors.lastname: Gerner-Smidt
authors.forename: Kåre
authors.initials: K
authors.lastname: Mølbak
mesh_terms: D001424:Bacterial Infections / Q000401:mortality*; D015331:Cohort Studies; D015897:Comorbidity; D003718:Denmark / Q000453:epidemiology; D005517:Foodborne Diseases / Q000401:mortality*; D005767:Gastrointestinal Diseases / Q000401:mortality*; D006801:Humans; D012042:Registries; D012044:Regression Analysis; D012307:Risk Factors