title: [The study on the anti-oxidation effect of root of Mallotus apelta in the rat model of liver fibrosis].
abstract: OBJECTIVE
  To investigate the effect of root of Mallotus apelta in treatment of liver fibrosis and the effect of anti-oxidation in the rat model of liver fibrosis.
  
  
  METHODS
  A rat model of liver fibrosis was induced with 40% CCl4 in peanut oil. A series of items were detected, which include ALT, AST, MDA, NO and hydroxyproline in the blood or liver tissues.
  
  
  RESULTS
  The level of ALT, MDA, NO in serum were significantly decreased, the level of hydroxyproline was declined too, while the formation of liver fibrosis was successfully ameliorated.
  
  
  CONCLUSIONS
  The root of Mallotus apelta could retain the progression of liver fibrosis, having a capacity of anti-oxidation. And the latter might be the reason of the former function.
authors.affiliation: First Military Medical University, Gunagzhou 510515.
authors.forename: Jinjun
authors.initials: J
authors.lastname: Zhao
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Lü
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Wang
authors.forename: Xufu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D002252:Carbon Tetrachloride Poisoning; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008106:Liver Cirrhosis, Experimental / Q000209:etiology / Q000378:metabolism*; D008297:Male; D036461:Mallotus Plant / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal