Correlation of mollicutes and their viruses with multiple sclerosis and other demyelinating diseases.
To identify infectious diseases likely involved in MS, the author previously correlated the geographical distribution of MS with the global distribution of tick-borne diseases. Tick-borne infectious agents include mollicutes or mycoplasmas. The current paper reviews evidence that mollicutes, especially spiroplasmas, or their viruses could be the initial exposure that causes MS. Mollicute infections, including the effects of their toxins, can be treated or prevented with gold salts or tetracyclines. If further research recommended by this review finds a role of mycoplasmas in MS, treatment of MS with gold with tetracycline should be evaluated.
Brown
James S
JS
McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249, USA. jbrown2185@aol.com
D000818:Animals; D003711:Demyelinating Diseases / Q000378:metabolism*; D006046:Gold / Q000494:pharmacology; D006801:Humans; D009103:Multiple Sclerosis / Q000378:metabolism*; D010957:Plasmids / Q000378:metabolism; D008973:Tenericutes / Q000821:virology*; D013752:Tetracycline / Q000494:pharmacology; D017282:Tick-Borne Diseases / Q000150:complications* / Q000821:virology; D013987:Ticks
D006046:Gold; D013752:Tetracycline