title: Fine-needle aspiration biopsy of solid aneurysmal bone cyst in the humerus.
abstract: We report the fine-needle aspiration biopsy (FNAB) cytology findings of a solid aneurysmal bone cyst in the left humerus of a 69-yr-old woman. Radiographically, the lesion showed an extensive, relatively well-defined osteolysis in the diaphysis, with a pathologic fracture. FNAB smears of the lesion consisted of benign, mononuclear cells and numerous osteoclast-like multinucleated giant cells. Some clusters of the mononuclear cells were closely associated with dense, homogeneous, extracellular, matrix material. To our knowledge, the FNAB features of solid ABC of the long bones have not been described previously in the English-language literature. The cytologic features are indistinguishable from those of giant cell tumors of bone and brown tumors of hyperparathyroidism.
authors.affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. yamatetu@med.kobe-u.ac.jp
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Keiko
authors.initials: K
authors.lastname: Nagira
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Akisue
authors.forename: Takashi
authors.initials: T
authors.lastname: Marui
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hitora
authors.forename: Teruya
authors.initials: T
authors.lastname: Kawamoto
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yoshiya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kurosaka
authors.forename: Ryuko
authors.initials: R
authors.lastname: Tsukamoto
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D017824:Bone Cysts, Aneurysmal / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D001859:Bone Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D018212:Giant Cell Tumor of Bone / Q000473:pathology; D006801:Humans; D006810:Humeral Fractures / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D006811:Humerus / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology; D006961:Hyperparathyroidism / Q000150:complications / Q000473:pathology; D010014:Osteolysis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography