Successful treatment of meningoencephalitis caused by methicillin-resistant Staphylococcus aureus with intrathecal vancomycin in an allogeneic peripheral blood stem cell transplant recipient.
Methicillin-resistant Staphylococcus aureus (MRSA) is a common infectious pathogen during stem cell trans-plantation. We report a case of meningoencephalitis with multiple abscess formation caused by MRSA, which occurred in a 4-year-old boy soon after allogeneic peripheral blood stem cell transplantation. We successfully cured the infection with a combination of intravenous and intrathecal vancomycin.
Matsubara
H
H
Divisions of Pediatric Oncology, National Cancer Hospital, Tokyo, Japan.
Makimoto
A
A
Higa
T
T
Kawamoto
H
H
Kanda
Y
Y
Kami
M
M
Tanosaki
R
R
Mineishi
S
S
Ohira
M
M
Takaue
Y
Y
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D007262:Infusions, Intravenous; D007278:Injections, Spinal; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D008590:Meningoencephalitis / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D016106:Methicillin Resistance; D016609:Neoplasms, Second Primary / Q000628:therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology; D013211:Staphylococcus aureus; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014640:Vancomycin / Q000008:administration & dosage / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D014640:Vancomycin