title: Clinical Sarcocystis neurona encephalomyelitis in a domestic cat following routine surgery.
abstract: Sarcocystis neurona is an important cause of equine protozoal myeloencephalitis (EPM) in horses in the Americas. An EPM-like neurological disease also has been reported from other mammals but it is difficult to induce this disease in the laboratory. A 4-month-old male domestic cat developed neurological signs 3 days following castration. The cat was euthanized 12 days later because of paralysis. Encephalomyelitis was the only lesion and was associated with numerous Sarcocystis schizonts and merozoites in the brain and spinal cord. The protozoa reacted positively with S. neurona-specific polyclonal rabbit antibody. Two unidentified sarcocysts were present in the cerebellum. It may be possible that stress of surgery triggered relapse of S. neurona infection in this cat.
authors.affiliation: Parasite Biology, Epidemiology and Systematics Laboratory, Agricultural Research Service, US Department of Agriculture, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, MD 20705-2350, USA. jdubey@anri.barc.usda.gov
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
authors.forename: J
authors.initials: J
authors.lastname: Benson
authors.forename: M A
authors.initials: MA
authors.lastname: Larson
mesh_terms: D000818:Animals; D001921:Brain / Q000469:parasitology / Q000473:pathology; D002371:Cat Diseases / Q000469:parasitology* / Q000473:pathology; D002415:Cats; D004679:Encephalomyelitis / Q000150:complications / Q000469:parasitology* / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009919:Orchiectomy / Q000662:veterinary; D012522:Sarcocystis / Q000302:isolation & purification; D012523:Sarcocystosis / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D013116:Spinal Cord / Q000469:parasitology / Q000473:pathology; D013312:Stress, Physiological / Q000150:complications / Q000662:veterinary