Pentoxifylline in the treatment of erythema nodosum leprosum.
Erythema nodosum leprosum (ENL) is a well-known serious complication affecting 10% of lepromatous multibacillary leprosy patients. In the chronic form, its morbidity may be considerable. Thalidomide and systemic steroids are the two current effective drugs for the management of ENL. However, their use in endemic countries is often difficult and hazardous, and a search for new therapies is needed. We report our experience on the effects of pentoxifylline, a methylxanthine derivative, which has recently been suggested as a possible effective treatment for ENL attacks.
De Carsalade
Georges-Yves
GY
Dispensaire de Mamoudzou, DASS de Mayotte, BP 104, 97600, Mamoudzou, Mayotte, France.
Achirafi
Aboubacar
A
Flageul
Béatrice
B
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D004334:Drug Administration Schedule; D004893:Erythema Nodosum / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D007917:Leprostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D015440:Leprosy, Lepromatous / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010431:Pentoxifylline / Q000008:administration & dosage / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome
D007917:Leprostatic Agents; D010431:Pentoxifylline