title: Mycotic aneurysm of the descending thoracic aorta caused by Pseudomonas aeruginosa in a solid organ transplant recipient: case report and review.
abstract: BACKGROUND
  Pseudomonas aeruginosa is a rare cause of aortic mycotic aneurysms. Optimal treatment, including reconstructive graft material and appropriate length of antibiotic therapy, is being debated.
  
  
  METHODS
  We describe a 26-year-old kidney-pancreas recipient who developed an aneurysm of the descending thoracic aorta caused by P. aeruginosa.
  
  
  RESULTS
  After surgical debridement and cryopreserved allograft reconstruction, parenteral antibiotics were continued for 12 months, at which time the patient was converted to oral antibiotic therapy. Within 6 months, he redeveloped a thoracic aortic aneurysm, necessitating reoperation and lifelong parenteral antibiotic therapy.
  
  
  CONCLUSIONS
  Herein we review and discuss the relevant literature concerning surgical and antibiotic treatment of mycotic thoracic aneurysms.
authors.affiliation: Department of Surgery, University of Minnesota, Mayo Mail Code 195, 420 Delaware Street SE, Minneapolis, MN 55455, USA. felti001@tc.umn.edu
authors.forename: Brad A
authors.initials: BA
authors.lastname: Feltis
authors.forename: David A
authors.initials: DA
authors.lastname: Lee
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Beilman
mesh_terms: D000328:Adult; D000785:Aneurysm, Infected / Q000628:therapy*; D017545:Aortic Aneurysm, Thoracic / Q000628:therapy*; D001398:Aztreonam / Q000008:administration & dosage*; D019917:Blood Vessel Prosthesis Implantation; D003646:Debridement; D004359:Drug Therapy, Combination / Q000008:administration & dosage*; D006801:Humans; D007263:Infusions, Parenteral / Q000379:methods; D008297:Male; D016377:Organ Transplantation; D010397:Penicillanic Acid / Q000008:administration & dosage* / Q000031:analogs & derivatives; D010878:Piperacillin / Q000008:administration & dosage*; D000077725:Piperacillin, Tazobactam Drug Combination; D011552:Pseudomonas Infections / Q000628:therapy*; D055502:Secondary Prevention; D016896:Treatment Outcome; D014640:Vancomycin / Q000008:administration & dosage*
chemical_list: D000077725:Piperacillin, Tazobactam Drug Combination; D014640:Vancomycin; D010397:Penicillanic Acid; D001398:Aztreonam; D010878:Piperacillin