[Preventing and treating effects of "changkun granules" on experimental acute renal failure induced by cisplatin in rats].
OBJECTIVE
To study the preventing and treating effects of "Changkun Granules" in experimental acute renal failure(ARF) induced by cisplatin in rats.


METHODS
The ARF rats were administered the "Changkun Granules". Serum BUN and SCr of all the rats were measured and the renal morphology was evaluated.


RESULTS
Serum BUN level in the "Changkun Granules" group was lower than the one in cisplatin group. "Changkun Granules" could also improve renal histology damage.


CONCLUSIONS
The results indicated that "Changkun Granules" had certain protective effect on experimental ARF.
Qiu
Yuwen
Y
Guangzhou Pharmaceutical Industrial Research Institute, 510240.
Ye
Liming
L
Feng
Weicheng
W
Guo
Tong
T
Liang
Jinqiang
J
Wu
Shuyi
S
Wang
Xueying
X
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000517:prevention & control*; D000818:Animals; D002945:Cisplatin / Q000494:pharmacology*; D008516:Medicine, Chinese Traditional; D051381:Rats
D002945:Cisplatin