Detection of human papillomavirus in sanitary napkins: a new paradigm in cervical cancer screening.
Human papillomavirus was successfully detected by polymerase chain reaction (PCR) in menstrual blood or vaginal discharge collected in sanitary napkins in 100% of 17 women having koilocytosis, cervical intraepithelial neoplasia, or squamous carcinoma. We advocate this form of cervical cancer screening because of its high sensitivity and acceptance by patients.
Tong
Tommy R
TR
Department of Pathology, Princess Margaret Hospital, Hong Kong, China. tommytong@yahoo.com
Chan
Olivia W H
OW
Chow
Tat-Chong
TC
Yu
Vivian
V
Leung
Kai-Man
KM
To
Shui-Him
SH
D041342:Absorbent Pads / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008598:Menstruation; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000821:virology
D004279:DNA, Viral