title: Effect of vaccination with refined components of the organism on infection of mice with Mycobacterium leprae.
abstract: Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton-the mycolyl-arabinogalactan-peptidoglycan complex-devoid of proteins is not protective.
authors.affiliation: National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand.
authors.forename: Maeya
authors.initials: M
authors.lastname: Ngamying
authors.forename: Pathom
authors.initials: P
authors.lastname: Sawanpanyalert
authors.forename: Raywadee
authors.initials: R
authors.lastname: Butraporn
authors.forename: Junjira
authors.initials: J
authors.lastname: Nikasri
authors.forename: Sang-Nae
authors.initials: SN
authors.lastname: Cho
authors.forename: Louis
authors.initials: L
authors.lastname: Levy
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Brennan
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D017358:Cell Wall Skeleton / Q000276:immunology; D005260:Female; D007918:Leprosy / Q000517:prevention & control*; D051379:Mice; D008807:Mice, Inbred BALB C; D009163:Mycobacterium bovis / Q000276:immunology; D009166:Mycobacterium leprae / Q000276:immunology*; D014611:Vaccination
chemical_list: D001428:Bacterial Vaccines; D017358:Cell Wall Skeleton