title: Highly enantioselective 1,4-addition of diorganozinc reagents to cyclic enones using chiral diphosphite ligands derived from H8-binaphthol.
abstract: [formula: see text] High enantioselectivities have been achieved in the 1,4-addition of dialkylzincs to 2-cyclopentenone, 2-cyclohexenone, and 2-cycloheptenone with ee values up to 99% by using chiral aryl diphosphite ligands derived from H8-binaphthol.
authors.affiliation: Open Laboratory of Chirotechnology, Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hong Kong, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Liang
authors.forename: Terry T L
authors.initials: TT
authors.lastname: Au-Yeung
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan