title: Two new methyl chanofruticosinates from Kopsia flavida blume.
abstract: Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1-decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N-decarbomethoxy-14,15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1-decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.
authors.affiliation: Department of Pharmacy, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia. khairana@medic.ukm.my
authors.forename: Khairana
authors.initials: K
authors.lastname: Husain
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Jantan
authors.forename: Ikram M
authors.initials: IM
authors.lastname: Said
authors.forename: Norio
authors.initials: N
authors.lastname: Aimi
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takayama
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D029062:Apocynaceae; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
chemical_list: D000470:Alkaloids; D010936:Plant Extracts