Highly efficient deprotection of aromatic acetals under neutral conditions using beta-cyclodextrin in water.
Aromatic acetals have been deprotected to the corresponding aldehydes under biomimetic conditions for the first time using beta-cyclodextrin in water under neutral conditions, thereby overcoming many of the drawbacks associated with earlier methodologies. This method, apart from being simple with regard to recycling of the catalyst, also has the potential for industrial applications.
Krishnaveni
N Srilakshmi
NS
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India ramaraok@iict.res.in
Surendra
K
K
Reddy
M Arjun
MA
Nageswar
Y V D
YV
Rao
K Rama
KR
D000080:Acetals / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D003505:Cyclodextrins / Q000737:chemistry*; D007202:Indicators and Reagents; D018716:Molecular Mimicry; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014867:Water / Q000737:chemistry
D000080:Acetals; D003505:Cyclodextrins; D007202:Indicators and Reagents; D014867:Water