title: Synthesis of 1,3-difluoroaromatics in one pot by addition of difluorocarbene from sodium chlorodifluoroacetate to 1,2-substituted cyclobutenes.
abstract: [formula: see text] The synthesis of 1,3-difluoro-2,4-diphenylbenzene has been accomplished in one step from 1,2-diphenylcyclobutene using the environmentally benign difluorocarbene precursor sodium chlorodifluoroacetate. In addition, the preparation of the previously unknown compound 1,3-difluoro-2,4-di-n-propylbenzene has been accomplished in one step from 1,2-di-n-propylcyclobutene using Seyferth's reagent (Ph-Hg-CF3) and sodium chlorodifluoroacetate.
authors.affiliation: Department of Chemistry, James Madison University, MSC 7701, Harrisonburg, Virginia 22807, USA.
authors.forename: Heather M
authors.initials: HM
authors.lastname: Morrison
authors.forename: James E
authors.initials: JE
authors.lastname: Rainbolt
authors.forename: Scott B
authors.initials: SB
authors.lastname: Lewis