title: Complication rate and diagnostic yield of 515 consecutive ultrasound-guided biopsies of renal allografts and native kidneys using a 14-gauge Biopty gun.
abstract: Our objective was to evaluate the safety and diagnostic efficacy of the ultrasound-guided renal biopsy procedure using an automated biopsy device (Biopty gun) with a 14-gauge needle. Five hundred fifteen consecutive ultrasound-guided renal biopsies performed in two large university hospitals were retrospectively reviewed. Three hundred forty-five biopsies were performed on renal allografts and 170 on native kidneys. The tissue specimen was adequate for histological evaluation in 95.3% of the cases (94.8% in the transplanted kidney group, 96.5% in the native kidney group). The overall complication rate was 12.2% and was significantly higher in the native kidney group (19.4%) than in the renal allograft group (8.7%). Major complications occurred in 2.7% of the cases (2.9% of the renal allografts and 2.4% of the native kidney biopsies), including one procedure-related death and the loss of the renal allograft in two other patients. Minor complications were noted in 9.5% of the biopsies and there were significantly more in the group of the native kidneys (17.1%) than in the group of the transplanted kidneys (5.8%). Renal biopsy with an automated device using a 14-gauge needle has a high tissue recovery rate, but it is associated with a small risk of serious complications.
authors.affiliation: Department of Radiology, Erasmus University Medical Center, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. Huurman@rond.azr.nl
authors.forename: Anda
authors.initials: A
authors.lastname: Preda
authors.forename: Lucas C
authors.initials: LC
authors.lastname: Van Dijk
authors.forename: Jacques A
authors.initials: JA
authors.lastname: Van Oostaijen
authors.forename: Peter M T
authors.initials: PM
authors.lastname: Pattynama
mesh_terms: D001707:Biopsy, Needle / Q000009:adverse effects* / Q000295:instrumentation; D015331:Cohort Studies; D005260:Female; D006406:Hematoma / Q000453:epidemiology / Q000209:etiology*; D006417:Hematuria / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology*; D016030:Kidney Transplantation / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology*; D008297:Male; D012016:Reference Values; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D015996:Survival Rate; D014184:Transplantation, Homologous / Q000473:pathology; D014463:Ultrasonography