title: [Acute exacerbation of interstitial pneumonia associated with active systemic lupus erythematosus in a patient with rheumatoid arthritis].
abstract: A 36-year-old woman with rheumatoid arthritis was admitted to our hospital for evaluation of newly developed active systemic lupus erythematosus (SLE). After hospitalization, she showed progressive respiratory failure. Chest CT revealed exacerbation of interstitial pneumonia, showing acute development of air-space consolidation and ground-glass opacity in addition to intensified reticular shadows. Administration of high-dose corticosteroids and cyclosporine A resulted in recovery from respiratory failure, accompanied by obvious improvement in the chest radiographs and CT, as demonstrated by the disappearance of air-space consolidation and ground-glass opacity. Clinically, the exacerbation of her interstitial pneumonia was compatible with acute lupus pneumonitis, a rare complication with active SLE.
authors.affiliation: Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors.forename: Ayaka
authors.initials: A
authors.lastname: Sadakata
authors.forename: Masao
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: Yoshikata
authors.initials: Y
authors.lastname: Misaki
authors.forename: Akiko
authors.initials: A
authors.lastname: Komiya
authors.forename: Yasuo
authors.initials: Y
authors.lastname: To
authors.forename: Motoyasu
authors.initials: M
authors.lastname: Iikura
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Yamada
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Tanaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Dohi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000208:Acute Disease; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000503:physiopathology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*