[Preimplantation genetic diagnosis: two successful cases]
OBJECTIVE: To establish a technology of preimplantation genetic diagnosis. METHODS: Intracytoplasm sperm injection and blastomere biopsy were performed on two women at the advanced age with the fallopian tube obstruction. Normal embryos were selected for embryo transfer after fluorescence in-situ hybridziation in biopsied blastomere. RESULTS: The levels of serum HCG were increased 20 days after embryo transfer and ultrasonography in 16 gestation weeks showed the fetal growth and structure are normal. CONCLUSION: Two successful clinical pregnancies achieved after preimplantation genetic diagnosis.
Jin
Fan
F
The Affiliated Obstetrics and Gynecology Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310006, China.
Xu
Chen-Ming
CM
Gao
Hui-Juan
HJ
Zhu
Yi-Min
YM
Qian
Yu-Li
YL
Ye
Ying-Hui
YH
Zhou
Fu-Zhen
FZ
Huang
He-Feng
HF