title: [Screening of benzodizepines and their metabolites in urine].
abstract: OBJECTIVE
  Screen seventeen benzodizepines and their metabolitesin urine by GC/ECD and GC/MS.
  
  
  METHODS
  They were GC (GC/ECD, GC/MS) assay of benzodizepines and GC (GC/ECD, GC/MS) assay of benzophenones of acid-hydrolytic products of 1,4-benzodizepines.
  
  
  RESULTS
  The methods were simple and sensitive. The recoverys were 60% to 90% of most benzodizepines, linear calibration curves were 20 ng/ml-200 ng/ml (r > 0.99), and detection limits were 0.5 ng/ml-10 ng/ml.
  
  
  CONCLUSIONS
  They methods were evaluated with human urine samples.
authors.affiliation: Institute of Forensic Sciences, Ministry of Justice, Shanghai 200063.
authors.forename: Bao-hua
authors.initials: BH
authors.lastname: Shen
authors.forename: Min
authors.initials: M
authors.lastname: Shen
authors.forename: Xian-yi
authors.initials: XY
authors.lastname: Zhuo
mesh_terms: D014151:Anti-Anxiety Agents / Q000378:metabolism / Q000652:urine*; D001569:Benzodiazepines / Q000378:metabolism / Q000652:urine*; D001577:Benzophenones / Q000378:metabolism / Q000652:urine; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans
chemical_list: D014151:Anti-Anxiety Agents; D001577:Benzophenones; D001569:Benzodiazepines