Further studies on the synthesis of 7,17-seco norditerpenoid alkaloids.
Following the report on the synthesis of the 7,17-seco compounds [Wang, F.P., Yang, J.S., Chen, Q.H., Yu, L. and Li, B.G. (2000), Chem. Pharm. Bull. 48, 1912-1916], further studies on the reaction optimization for cleavage of the C(7),C(17) bond led to the 7,17-seco norditerpenoid alkaloids (e.g. 4, 9) in nearly 90% yield.
Chen
Qiao-Hong
QH
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, China.
Wang
Feng-Peng
FP
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010946:Plants, Medicinal; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry
D000470:Alkaloids; D013729:Terpenes