title: Improvement in mitral regurgitation after aortic valve replacement.
abstract: BACKGROUND
  Concomitant mitral valve regurgitation is often present in patients with aortic stenosis. The additional MV replacement is associated with high operative risk. Previous studies have shown an amelioration of MV regurgitation after aortic valve replacement but most of the patient groups were heterogenous.
  
  
  OBJECTIVE
  To determine whether AV replacement for aortic stenosis has any effect on MV regurgitation.
  
  
  METHODS
  We reviewed two-dimensional echocardiography and color flow Doppler assessment of both aortic stenosis and MV regurgitation severity in 30 patients. Patients with previous MV surgery, organic MV disease, occlusive carotid artery disease, ejection fraction < 50%, and coexisting significant AV regurgitation were excluded. Preoperatively, MV regurgitation was mild in 23 patients (77%) and moderate in 7 (23%); in no patient was the condition severe. All patients had severe atrial stenosis (peak average aortic gradient 86 +/- 22 mmHg in the mild MV regurgitation group and 83 +/- 26 mmHg in the moderate group). The patients were divided into two groups according to the severity of MV regurgitation (associated mild, and moderate). Group 2, with moderate MV regurgitation, was the most problematic in terms of decision making for concomitant MV surgery. Therefore, additional assessment of several parameters was required.
  
  
  RESULTS
  There was a significant decrease in MV regurgitation area (7.6 +/- 1.9 vs. 3.0 +/- 1.2 cm2, P < or = 0.012) and percent (28 +/- 5% vs. 12 +/- 6%, P < or = 0.001) between pre- and postoperative evaluation. Thus, the severity of the condition in all patients with moderate MV regurgitation decreased after AV replacement; in the mild group it remained unchanged in 53% or improved in 47%. There was no association between the preoperative gradient on the aortic valve and the degree of MV regurgitation.
  
  
  CONCLUSIONS
  In our population of patients with severe atrial stenosis there were no patients with coexisting severe MV regurgitation. The decision to repair or replace a severely leaking mitral valve is an easy one, as in mild MV regurgitation. The clinical problem often presents in patients with severe aortic stenosis and moderate MV regurgitation. We believe that additional MV surgery is not necessary, at least in patients with preserved left ventricular function and without organic MV disease.
authors.affiliation: Institute of Cardiology, Kaplan Medical Center, Rehovot, Israel. sorel6@012.net.il
authors.forename: Sorel
authors.initials: S
authors.lastname: Goland
authors.forename: Gaby
authors.initials: G
authors.lastname: Loutaty
authors.forename: Alexander
authors.initials: A
authors.lastname: Arditi
authors.forename: Eitan
authors.initials: E
authors.lastname: Snir
authors.forename: Itzhak
authors.initials: I
authors.lastname: Abend
authors.forename: Abraham
authors.initials: A
authors.lastname: Caspi
mesh_terms: D000368:Aged; D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D018618:Echocardiography, Doppler, Color; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D012189:Retrospective Studies