title: Epiphyseal involvement of simple bone cysts.
abstract: Epiphyseal involvement of a simple bone cyst (SBC) is uncommon. Eight patients are reported in whom an SBC was found to cross the growth plate, involving the epiphysis in seven patients and the apophysis in one. All patients had more than two pathologic fractures. In seven patients growth disturbance was found. Functional impairment did not develop in any patient. Radiographically, all lesions presented a characteristic involvement of the epiphysis and metaphysis in various proportions. Only one of four cysts treated with methylprednisolone acetate injections showed incomplete healing; the others failed to respond. After percutaneous grafting of autologous bone marrow, three of seven cysts healed and the others attained incomplete healing. Epiphyseal involvement of SBC should be considered a more aggressive form of an active lesion.
authors.affiliation: Department of Pediatric Orthopaedics, Dana Children's Hospital, Tel-Aviv, Israel.
authors.forename: Dror
authors.initials: D
authors.lastname: Ovadia
authors.forename: Elias
authors.initials: E
authors.lastname: Ezra
authors.forename: Eitan
authors.initials: E
authors.lastname: Segev
authors.forename: Shlomo
authors.initials: S
authors.lastname: Hayek
authors.forename: David
authors.initials: D
authors.lastname: Keret
authors.forename: Shlomo
authors.initials: S
authors.lastname: Wientroub
authors.forename: Franklin
authors.initials: F
authors.lastname: Lokiec
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D002648:Child; D004838:Epiphyses / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077555:Methylprednisolone Acetate; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000893:Anti-Inflammatory Agents; D000077555:Methylprednisolone Acetate; D008775:Methylprednisolone