title: Congenital adrenal hypoplasia presenting as a chronic respiratory condition.
abstract: We describe two children with oxygen dependence, which resolved when congenital adrenal hypoplasia was diagnosed and treatment initiated. Chronic respiratory distress can be a symptom of adrenal hypoplasia and this should be taken into consideration when investigating a child with unexplained chronic respiratory difficulties. Respiratory symptoms resolve very quickly when the underlying condition is recognised and treated.
authors.affiliation: Paediatric Department, Bradford Royal Informary, UK.
authors.forename: K
authors.initials: K
authors.lastname: Schwarz
authors.forename: R
authors.initials: R
authors.lastname: Thwaites
authors.forename: A
authors.initials: A
authors.lastname: Minford
authors.forename: C
authors.initials: C
authors.lastname: Day
authors.forename: G
authors.initials: G
authors.lastname: Butler
mesh_terms: D000307:Adrenal Gland Diseases / Q000151:congenital / Q000175:diagnosis / Q000188:drug therapy; D000311:Adrenal Glands / Q000002:abnormalities*; D003937:Diagnosis, Differential; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007223:Infant; D007231:Infant, Newborn; D008901:Mineralocorticoids / Q000627:therapeutic use; D012120:Respiration Disorders / Q000175:diagnosis* / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D008901:Mineralocorticoids; D005438:Fludrocortisone; D006854:Hydrocortisone