Mirtazapine for pruritus.
Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies. Medical management recently has included the use of ondansetron and paroxetine. We report four patients whose pruritus responded to mirtazapine.
Davis
Mellar P
MP
The Harry R. Horvitz Center for Palliative Medicine, Cleveland, OH, USA.
Frandsen
Jan L
JL
Walsh
Declan
D
Andresen
Steven
S
Taylor
Sandy
S
D000368:Aged; D000369:Aged, 80 and over; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D002779:Cholestasis / Q000150:complications; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D008875:Middle Aged; D000078785:Mirtazapine; D009369:Neoplasms / Q000150:complications; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D051437:Renal Insufficiency / Q000150:complications
D000929:Antidepressive Agents, Tricyclic; D006634:Histamine H1 Antagonists; D008803:Mianserin; D000078785:Mirtazapine