Bullous eosinophilic cellulitis (Wells' syndrome) associated with Churg-Strauss syndrome.
We report a patient with Churg-Strauss syndrome (CSS) with asthma, eosinophilia, nasal polyposis and ANCA-associated multisystem vasculitis, who's skin eruption started with erythematous urticarial-plaques followed by haemorrhagic bullae. Histology of the plaques revealed 'flame figures' in the dermis with no granulomatous or vasculitic process, consistent with the diagnosis of eosinophilic cellulitis or Wells' syndrome. The association of CSS and Wells' syndrome observed in this patient may have a common pathogenesis. CSS may induce Wells' syndrome by an unknown factor.
Schuttelaar
M L A
ML
Centre for Blistering Skin Diseases, Department of Dermatology, Groningen University Hospital, Groningen, The Netherlands. m.l.schuttelaar@derm.azg.nl
Jonkman
M F
MF
D002481:Cellulitis / Q000150:complications*; D015267:Churg-Strauss Syndrome / Q000150:complications*; D004802:Eosinophilia / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000150:complications*