New, simple and cheap alternative to troponin test for diagnosis of acute myocardial infarction.
Acute myocardial infarction (AMI) is often a fatal disorder in humans seen throughout the world. It was earlier diagnosed with some serum enzymes like aspartate transaminase, creatine phosphokinase and its isoenzyme CPK-MB and lactate dehydrogenase which were shown to be increased in AMI. However, in the last few years importance has been given to measuring serum troponins released from the injured myocardium to confirm an AMI. Troponin estimation involves immunological technique, which is expensive with other associated problems like shelf life of reagents, number of samples to be analysed and availability of the kit itself, used for estimation. Under these circumstances the present work involves the measurement of total salt soluble proteins which are proteins associated with troponins also released from myocardium of a patient with AMI. This new test overrules all the disadvantages of the troponin test but seems equally viable and useful for diagnosis of AMI.
Bhaskar
Indira
I
Department of Biochemistry, Kasturba Medical College & Centre for Basic Sciences, Bejai, Mangalore 575 004, India.
Rao
Shrinivas B
SB
D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic / Q000191:economics / Q000592:standards*; D014336:Troponin
D011933:Reagent Kits, Diagnostic; D014336:Troponin