title: Sample Power and ExpDesign: tools for improving design of animal experiments.
abstract: Proper experimental design, involving the correct number of animals, should be a basic skill for any scientist working with animals. The authors describe a university-developed and freely available tutorial program and an interactive computer-assisted learning program, both of which guide students through the steps necessary for designing animal experiments and estimating optimal sample sizes.
authors.affiliation: Department of Pharmacology, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, the Netherlands. Hvwilgenburg@cs.com
authors.forename: Henk
authors.initials: H
authors.lastname: van Wilgenburg
authors.forename: Piet G
authors.initials: PG
authors.lastname: van Schaick Zillesen
authors.forename: Iva
authors.initials: I
authors.lastname: Krulichova
mesh_terms: D000700:Analgesics / Q000494:pharmacology; D000827:Animal Welfare; D000818:Animals; D003194:Computer-Assisted Instruction; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006358:Hot Temperature; D008614:Meperidine / Q000494:pharmacology; D051379:Mice; D010146:Pain / Q000517:prevention & control; D012107:Research Design / Q000706:statistics & numerical data*; D018401:Sample Size
chemical_list: D000700:Analgesics; D008614:Meperidine