title: Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates.
abstract: Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.
authors.affiliation: Department of Microbiology and Immunology, Division of Infectious Diseases, Stanford University, Stanford, California 94305, USA. eleonard@stanford.edu
authors.forename: Edward E
authors.initials: EE
authors.lastname: Leonard
authors.forename: Tohru
authors.initials: T
authors.lastname: Takata
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Blaser
authors.forename: Stanley
authors.initials: S
authors.lastname: Falkow
authors.forename: Lucy S
authors.initials: LS
authors.lastname: Tompkins
authors.forename: Erin C
authors.initials: EC
authors.lastname: Gaynor
mesh_terms: D000818:Animals; D002169:Campylobacter Infections / Q000453:epidemiology; D016123:Campylobacter jejuni / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D002417:Cattle; D004269:DNA, Bacterial; D020869:Gene Expression Profiling; D005838:Genotype; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D016366:Open Reading Frames; D019105:Random Amplified Polymorphic DNA Technique
chemical_list: D004269:DNA, Bacterial