title: Simultaneous congenital and acquired extrahepatic portosystemic shunts in two dogs.
abstract: Two dogs with simultaneous congenital and acquired portosystemic shunts are reported. The first dog was an eight-month-old, male Golden Retriever with a history of peritoneal effusion, polyuria/polydipsia, and stunted growth. The dog had a microcytic, hypochromic anemia, a mildly elevated AST, and a moderate to severely elevated preprandial and postprandial serum bile acids. Transcolonic portal scintigraphy confirmed the presence of a portosystemic shunt. An intraoperative mesenteric portogram was performed. Two conjoined congenital extrahepatic portosystemic shunts and multiple acquired extrahepatic portosystemic shunts were identified. The second dog was a five-month-old, mixed breed with two week history of peritoneal effusion. Abdominal ultrasound and transcolonic scintigraphy were used to diagnose a portosystemic shunt. A single extrahepatic portosystemic shunt, portal hypertension, and multiple acquired collateral shunts were identified at surgery. The histologic alterations observed in these dogs were consistent with a portosystemic shunt. In these dogs, the presence of congenital and acquired portosystemic shunts and histopathologic findings are considered to represent a combination of congenital portosystemic shunts and noncirrhotic portal hypertension or portal vein hypoplasia.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100102, Gainesville, FL 32610, USA.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Ferrell
authors.forename: John P
authors.initials: JP
authors.lastname: Graham
authors.forename: Rita
authors.initials: R
authors.lastname: Hanel
authors.forename: Susan
authors.initials: S
authors.lastname: Randell
authors.forename: James P
authors.initials: JP
authors.lastname: Farese
authors.forename: William L
authors.initials: WL
authors.lastname: Castleman
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D004285:Dogs; D006501:Hepatic Encephalopathy / Q000151:congenital / Q000473:pathology / Q000662:veterinary*; D006975:Hypertension, Portal / Q000150:complications / Q000662:veterinary*; D007813:Laparotomy / Q000662:veterinary; D008297:Male; D011169:Portal Vein / Q000002:abnormalities* / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging