title: [The role of leptin in human reproduction].
abstract: The article reviews the current literature about leptin, a hormone produced mainly in the adipose tissue, in terms of its role in reproduction. The structure of leptin, its biological activity as well as its influence on secretion of their hormones has been discussed. The leptin concentrations during the ovulatory cycle, pregnancy puerperium and assisted reproduction have been presented. It has been suggested that leptin may have an advantageous effect not only on oocyte and zygote development in the early stages, but also on the process of implantation and therefore its evaluation may be useful for the clinical determination of embryo quality in IVF-ET program.
authors.affiliation: Katedry i Kliniki Połoznictwa i Chorób Kobiecych AM w Bydgoszczy.
authors.forename: Marek
authors.initials: M
authors.lastname: Grabiec
authors.forename: Wiesław
authors.initials: W
authors.lastname: Szymański
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D020738:Leptin / Q000378:metabolism*; D010060:Ovulation / Q000378:metabolism; D010062:Ovulation Induction / Q000379:methods; D049590:Postpartum Period / Q000378:metabolism; D011247:Pregnancy; D012098:Reproduction / Q000502:physiology
chemical_list: D020738:Leptin