Chemokine signaling: rules of attraction.
The chemokine SDF-1 and its receptor CXCR4 control cell migration in the immune and nervous systems. Recent studies in zebrafish have shown that SDF-1 and CXCR4 also guide the migration of germ cells and sensory organs of the lateral line.
Schier
Alexander F
AF
Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. schier@saturn.med.nyu.edu
D000818:Animals; D054377:Chemokine CXCL12; D019743:Chemokines, CXC / Q000378:metabolism*; D004627:Embryonic Induction / Q000502:physiology*; D005854:Germ Cells / Q000378:metabolism; D019718:Receptors, CXCR4 / Q000378:metabolism; D015027:Zebrafish / Q000196:embryology / Q000502:physiology
D054377:Chemokine CXCL12; D019743:Chemokines, CXC; D019718:Receptors, CXCR4