Does C-reactive protein predict cardiovascular events in women better than LDL?
C-reactive protein (CRP) is an independent predictor of a first cardiovascular event in women and appears to be a stronger predictor than low-density lipoprotein (LDL) cholesterol levels. Unfortunately, this information does not lead directly to a therapeutic intervention. As an accompanying editorial stated, low carotenoid levels also predict cardiovascular events, but supplementation with beta carotene does not reduce an individual's risk. This study does not clarify whether CRP is a causative agent, a marker, or a result of cardiovascular disease. Our focus should remain on identifying and treating conventional risk factors until we better understand the exact role CRP has in therapeutic decisions regarding cardiovascular disease.
Stevermer
James J
JJ
Department of Family and Community Medicine, University of Missouri-Columbia, USA. stevermerj@health.missouri.edu.
D002097:C-Reactive Protein; D002318:Cardiovascular Diseases / Q000097:blood / Q000175:diagnosis* / Q000517:prevention & control; D008078:Cholesterol, LDL; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors
D008078:Cholesterol, LDL; D002097:C-Reactive Protein