title: Surgical treatment of breast cancer in previously augmented patients.
abstract: The incidence of breast cancer is increasing each year. Concomitantly, cosmetic breast augmentation has become the second most often performed cosmetic surgical procedure. As the augmented patient population ages, an increasing number of breast cancer cases among previously augmented women can be anticipated. The surgical treatment of these patients is controversial, with several questions remaining unanswered. Is breast conservation therapy feasible in this patient population and can these patients retain their implants? A retrospective review of all breast cancer patients with a history of previous augmentation mammaplasty who were treated at the Revlon/UCLA Breast Center between 1991 and 2001 was performed. During the study period, 58 patients were treated. Thirty patients (52 percent) were treated with a modified radical mastectomy with implant removal. Twenty-eight patients (48 percent) underwent breast conservation therapy, which consisted of lumpectomy, axillary lymph node dissection, and radiotherapy. Twenty-two of the patients who underwent breast conservation therapy initially retained their implants. Eleven of those 22 patients (50 percent) ultimately required completion mastectomies with implant removal because of implant complications (two patients), local recurrences (five patients), or the inability to obtain negative margins (four patients). Nine additional patients experienced complications resulting from their implants, including contracture, erosion, pain, and rupture. The data illustrate that breast conservation therapy with maintenance of the implant is not ideal for the majority of augmented patients. Breast conservation therapy with explantation and mastopexy might be appropriate for rare patients with large volumes of native breast tissue. Mastectomy with immediate reconstruction might be a more suitable choice for these patients.
authors.affiliation: Division of Plastic and Reconstructive Surgery and Surgical Oncology, Revlon/UCLA Breast Center, UCLA Medical Center, Los Angeles, CA, USA. ykaranas@stanford.edu
authors.forename: Yvonne L
authors.initials: YL
authors.lastname: Karanas
authors.forename: Darren S
authors.initials: DS
authors.lastname: Leong
authors.forename: Andrew
authors.initials: A
authors.lastname: Da Lio
authors.forename: Kathleen
authors.initials: K
authors.lastname: Waldron
authors.forename: James P
authors.initials: JP
authors.lastname: Watson
authors.forename: Helena
authors.initials: H
authors.lastname: Chang
authors.forename: William W
authors.initials: WW
authors.lastname: Shaw
mesh_terms: D000328:Adult; D019928:Breast Implantation; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000601:surgery*