[The prospects of vaccination against H. pylori infection].
H. pylori causes numerous gastroduodenal diseases including malignancies. Although eradication of H. pylori using antibiotics is clinically performed, it is sometimes unsuccessful because of resistant bacteria and patient non-compliance with treatment. Therefore prophylactic and therapeutic vaccination against H. pylori infection is necessary for clinical use but it is still under study. H. pylori is widely believed to be transmitted in childhood. If long and chronic H. pylori infection causes gastric cancer, vaccination should be targeted at children for the prophylaxis of cancer. Systemic immunization with aluminum hydroxide which has been already proved to be safe for human child, deserve attention.
Minoura
Takanori
T
Department of Pediatrics, Tohoku University Graduate School of Medicine.
Nishizono
Akira
A
D001428:Bacterial Vaccines; D016481:Helicobacter Infections / Q000517:prevention & control / Q000628:therapy*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D016233:Immunotherapy, Active
D001428:Bacterial Vaccines