title: Comparison of PTFE, pericardium bovine and fascia lata for repair of incisional hernia in rat model, experimental study.
abstract: Incisional hernia is a frequent complication of abdominal surgery developing in 11-20 % of patients undergoing an abdominal operation. Regarding morbidity and loss of manpower, incisional hernias continue to be a fundamental problem for surgeons. In this experimental study, three commonly used mesh materials (Goretex PTFE; Tutoplast Fascia lata; Tutopatch Pericardium bovine) were compared according to effectiveness, strength, adhesion formation, histological changes, and early complications. Three groups, each consisting of 14 rats, have been formed as group A: polytetrafluoroethylene (PTFE), group B: pericardium bovine and group C: fascia lata. Evaluations were achieved at the end of the first and second postoperative week, respectively. Adhesion formation, wound maturation, bursting pressure, and tensile strength were evaluated. No statistically significant difference regarding adhesion formation was observed between groups although adhesion formation was less significant in PTFE and pericardium bovine groups than in the fascia lata group. Bursting pressure and tensile strength values were significantly higher in PTFE group than in the fascia lata group ( P<0.05). No statistically significant difference was observed between groups regarding wound maturation. In this experimental model, PTFE and pericardium bovine were found to be superior to fascia lata in abdominal wall repair.
authors.affiliation: Cerrahpasa Medical Faculty, Department of General Surgery, Istanbul University, Turkey. selinkapan@turk.net
authors.forename: S
authors.initials: S
authors.lastname: Kapan
authors.forename: M
authors.initials: M
authors.lastname: Kapan
authors.forename: E
authors.initials: E
authors.lastname: Goksoy
authors.forename: I
authors.initials: I
authors.lastname: Karabicak
authors.forename: H
authors.initials: H
authors.lastname: Oktar
mesh_terms: D000818:Animals; D002417:Cattle; D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D004195:Disease Models, Animal; D005206:Fascia Lata / Q000637:transplantation*; D006555:Hernia, Ventral / Q000473:pathology / Q000601:surgery*; D008297:Male; D010496:Pericardium / Q000637:transplantation*; D011138:Polytetrafluoroethylene / Q000009:adverse effects / Q000627:therapeutic use*; D011183:Postoperative Complications; D019919:Prosthesis Implantation / Q000009:adverse effects*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013718:Tensile Strength; D013997:Time Factors; D000267:Tissue Adhesions / Q000209:etiology / Q000473:pathology
chemical_list: D011138:Polytetrafluoroethylene