Towards an e-biology of ageing: integrating theory and data.
Ageing is a highly complex process; it involves interactions between numerous biochemical and cellular mechanisms that affect many tissues in an organism. Although work on the biology of ageing is now advancing quickly, this inherent complexity means that information remains highly fragmented. We describe how a new web-based modelling initiative is seeking to integrate data and hypotheses from diverse biological sources.
Kirkwood
Thomas B L
TB
Institute for Ageing and Heath, University of Newcastle, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK.
Boys
Richard J
RJ
Gillespie
Colin S
CS
Proctor
Carole J
CJ
Shanley
Daryl P
DP
Wilkinson
Darren J
DJ
D000375:Aging; D000818:Animals; D016922:Cellular Senescence; D003198:Computer Simulation; D006801:Humans; D020407:Internet; D008954:Models, Biological; D012984:Software; D013997:Time Factors