Lymphangioleiomyomatosis associated with pulmonary metastasis from an occult papillary carcinoma of the thyroid: report of a case occurring in a patient without tuberous sclerosis.
We report on 50-year-old woman without tuberous sclerosis, presenting with recurrent spontaneous pneumothorax. A CT-scan of the chest showed multiple, bilateral, thin-walled cysts, consistent with pulmonary lymphangioleiomyomatosis. A videothoracoscopic lung biopsy confirmed the diagnosis of lymphangioleiomyomatosis, but revealed also a micrometastasis from an occult papillary carcinoma of the thyroid gland. The main histologic differential diagnosis and the possible correlation between lymphangioleiomyomatosis and thyroid diseases are briefly discussed.
Cavazza
Alberto
A
Department of Pathology, S. Maria Nuova Hospital, Reggio Emilia, Italy. cavazza.alberto@asmn.re.it
Roggeri
Alberto
A
Zini
Michele
M
Rossi
Giulio
G
Zucchi
Luigi
L
D002291:Carcinoma, Papillary / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary*; D018192:Lymphangioleiomyomatosis / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology*