title: Changes in dietary bioaccumulation of tributyltin chloride (TBTCl) in red sea bream (Pagrus major) with the concentration in feed.
abstract: The effect of the concentration of tributyltin (TBT) in feed on the dietary bioaccumulation of tributyltin chloride (TBTCl) was studied in an 8-week uptake experiment and a 4-week elimination experiment using red sea bream (Pagrus major). The biomagnification factor (BMF) and the assimilation efficiency (AE) decreased from 0.30 to 0.15 and from 13% to 5.9%, respectively, as the TBT concentration in feed increased from 1.3 to 20 microg/g. The elimination rate constant (k(2)) was independent of the TBT concentration in the fish. Laboratory measurements of the BMF and AE of TBTCl underestimate actual field values if highly contaminated feed is used. Judging from the BMF and AE, the risk of the bioaccumulation of TBTCl through the food chain might be smaller than that of polychlorinated biphenyls.
authors.affiliation: National Research Institute of Fisheries and Environment of Inland Sea, Fisheries Research Agency, 2-17-5 Maruishi Ohno, Saeki, Hiroshima 739-0452, Japan. kikeda@fra.affrc.go.jp
authors.forename: Kumiko
authors.initials: K
authors.lastname: Ikeda
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamada
mesh_terms: D000818:Animals; D004032:Diet; D004781:Environmental Exposure; D020387:Food Chain; D018570:Risk Assessment; D021541:Sea Bream / Q000502:physiology*; D014018:Tissue Distribution; D014220:Trialkyltin Compounds / Q000493:pharmacokinetics*; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics*
chemical_list: D014220:Trialkyltin Compounds; D014874:Water Pollutants, Chemical; C011559:tributyltin