The reactions of cyclization of semicarbazide derivatives of 1,3-diphenyl-1,2,4-triazolin-5-thione-4-acetic acid.
In the reaction of hydrazide of 1,3-diphenyl-1,2,4-triazolin-5-thione-4-acetic acid with isocyanates. semicarbazide derivatives of 1,3-diphenyl-1,2,4-triazolin-5-thione-4-acetic acid [I-X] were obtained. Cyclization of these compounds in the presence of 2% NaOH led to the formation of derivatives of 1,2,4-triazolin-5-one [XI-XX].
Dobosz
Maria
M
Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 6 Staszica Str., 20-081 Lublin, Poland.
Pitucha
Monika
M
Chudnicka
Alina
A
D019342:Acetic Acid / Q000737:chemistry / Q000494:pharmacology; D003500:Cyclization; D008826:Microbial Sensitivity Tests; D012663:Semicarbazides / Q000737:chemistry* / Q000494:pharmacology; D014230:Triazoles / Q000737:chemistry* / Q000494:pharmacology
D012663:Semicarbazides; D014230:Triazoles; D019342:Acetic Acid