Biodegradable thermoresponsive poly(amino acid)s.
Reaction of poly(succinimide) with a mixture of 5-aminopentanol and 6-aminohexanol produced new thermoresponsive polymers based on biodegradable poly(amino acids)s, poly(N-substituted alpha/beta-asparagine)s, showing a clear LCST in water.
Tachibana
Yoichi
Y
Department of Materials Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 606-8501, Japan.
Kurisawa
Motoichi
M
Uyama
Hiroshi
H
Kakuchi
Toyoji
T
Kobayashi
Shiro
S
D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry*; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry; D006358:Hot Temperature; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*
D001672:Biocompatible Materials; D004337:Drug Carriers; D010455:Peptides; C045164:polyasparagine; C025252:poly-DL-succinimide; D001224:Aspartic Acid