Innate immunity in th e cornea: a putative role for keratocytes in the chemokine response to viral infection of the human corneal stroma.
Existing evidence suggests that chemokine expression by virus-infected cells is a common response to viral infection. By such a mechanism, non-immunologic cells may participate in the generation of an early innate immune response to infection. In the absence of classic immunologic cells in the corneal stroma, keratocytes may play a similar role in the corneal responses to viral infection.
Natarajan
Kanchana
K
Department of Ophthalmology, Molecular Pathogenesis of Eye Infection Research Center, Dean A. McGee Eye Institute, Oklahoma City, Oklahoma, USA.
Chodosh
James
J
Kennedy
Ronald
R
D000818:Animals; D018925:Chemokines / Q000378:metabolism*; D003315:Cornea / Q000276:immunology* / Q000378:metabolism* / Q000473:pathology; D003319:Corneal Stroma / Q000821:virology*; D006801:Humans; D007109:Immunity; D014777:Virus Diseases / Q000276:immunology* / Q000378:metabolism* / Q000473:pathology
D018925:Chemokines