title: The typical Cochrane review. How many trials? How many participants?
abstract: OBJECTIVE
  To describe the number of trials and participants in a typical systematic review from The Cochrane Database of Systematic Reviews.
  
  
  METHODS
  The number of trials in 1,000 Cochrane systematic reviews in issue 1, 2001 of The Cochrane Database of Systematic Reviews was counted for three categories of trial: included trials, ongoing trials, and trials awaiting assessment for inclusion. (The term trial is used in this paper, although a small number of Cochrane reviews include studies that are not trials.) The total number of participants in included trials was extracted from a sample of reviews.
  
  
  RESULTS
  A total of 9,778 trials were included in the Cochrane reviews. There were a further 356 ongoing trials and 1,138 trials awaiting assessment for inclusion. A typical review contained six included trials. Forty percent of the reviews listed ongoing trials and/or trials awaiting assessment for inclusion. Based on a sample of 258 reviews, the median number of participants per review was 945 (interquartile range, 313 to 2,511) per review and 118 (interquartile range, 60 to 241) per trial.
  
  
  CONCLUSIONS
  This report is a descriptive study of the number of trials and participants in a typical Cochrane review from The Cochrane Library, issue 1, 2001.
authors.forename: Susan
authors.initials: S
authors.lastname: Mallett
authors.forename: Mike
authors.initials: M
authors.lastname: Clarke
mesh_terms: D016206:Databases, Bibliographic; D019317:Evidence-Based Medicine; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*; D006113:United Kingdom