title: Plant defense: one post, multiple guards?!
abstract: Arabidopsis RIN4 is a key bacterial virulence target that is guarded by the resistance (R) protein RPM1. Two recent studies suggest that another R protein, RPS2, also guards RIN4. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 alter this key protein. R proteins RPM1 and RPS2 recognize the altered status and initiate a defense-signaling response. The guard hypothesis is in!
authors.affiliation: Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.
authors.forename: Rajendra
authors.initials: R
authors.lastname: Marathe
authors.forename: S P
authors.initials: SP
authors.lastname: Dinesh-Kumar
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000382:microbiology* / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000502:physiology; D001426:Bacterial Proteins / Q000502:physiology; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology; D017343:Genes, Plant; D047908:Intracellular Signaling Peptides and Proteins; D008954:Models, Biological; D010935:Plant Diseases / Q000235:genetics / Q000382:microbiology; D011549:Pseudomonas / Q000472:pathogenicity / Q000502:physiology; D014774:Virulence / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; C453279:RIN4 protein, Arabidopsis