Analysis of Case II drug transport with radial and axial release from cylinders.
Analysis is presented for Case II drug transport with axial and radial release from cylinders. The previously reported [J. Control Release 5 (1987) 37] relationships for radial release from films and slabs are special cases of the general solution derived in this study. The widely used exponential relation M(t)/M(infinity) = kt(n) describes nicely the first 60% of the fractional release curve when Case II drug transport with axial and radial release from cylinders is operating.
Kosmidis
Kosmas
K
Department of Physics, University of Thessaloniki, Thessaloniki 54124, Greece.
Rinaki
Eleni
E
Argyrakis
Panos
P
Macheras
Panos
P
D000465:Algorithms; D003692:Delayed-Action Preparations / Q000737:chemistry*; D004058:Diffusion; D004337:Drug Carriers / Q000737:chemistry*; D007700:Kinetics; D008956:Models, Chemical; D011108:Polymers / Q000737:chemistry*; D013997:Time Factors
D003692:Delayed-Action Preparations; D004337:Drug Carriers; D011108:Polymers