Comparison of neonatal effects of epidural and general anesthesia for cesarean section.
We assessed the influence of anesthetic technique for cesarean section on neonatal outcome. Thirty parturient women (ASA I/II) were randomly allocated into two groups. In Group GA general anesthesia was induced with 4 mg.kg(-1) thiopental and 1.5 mg.kg(-1) succinylcholine. In group EA epidural anesthesia was performed with 20 ml 0.375% bupivacaine through L(3-4) inter-space. 1-min Apgar scores were significantly higher in group EA (p < 0.001). Neurologic and Adaptive Capacity scores at 2 and 24 h were higher in group EA (p < 0.001). In terms of blood gas values, umbilical arterial pH and pO(2) values were higher in group EA (p < 0.05 and p < 0.001, respectively). The first breast-feeding intervals were found to be shorter in group EA (p < 0.001). We conclude that in terms of better Apgar and NAC scores, acid-base status and earlier initiation of breast-feeding, the epidural anesthesia may be preferred to general anesthesia in cesarean section.
Sener
Elif Bengi
EB
Department of Anesthesiology and Reanimation, Ondokuzmayis Universit, and University Faculty of Medicine, Samsun, Turkey. bengimd@hotmail.com
Guldogus
Fuat
F
Karakaya
Deniz
D
Baris
Sibel
S
Kocamanoglu
Serhat
S
Tur
Ayla
A
D000328:Adult; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000009:adverse effects / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000494:pharmacology; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000494:pharmacology; D001034:Apgar Score; D002045:Bupivacaine / Q000008:administration & dosage / Q000494:pharmacology; D002585:Cesarean Section / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007530:Isoflurane / Q000008:administration & dosage / Q000494:pharmacology; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D013390:Succinylcholine / Q000008:administration & dosage; D013874:Thiopental / Q000008:administration & dosage
D018685:Anesthetics, Inhalation; D000779:Anesthetics, Local; D007530:Isoflurane; D013390:Succinylcholine; D013874:Thiopental; D009609:Nitrous Oxide; D002045:Bupivacaine