Peripheral keratitis associated with erythema elevatum diutinum.
OBJECTIVE
To describe a case of peripheral keratitis associated with erythema elevatum diutinum (EED), an unusual immune-complex-mediated cutaneous vasculitis.


METHODS
Observational case report.


METHODS
A 25-year-old man who was diagnosed 15 months previously with erythema elevatum diutinum presented with an inflammatory peripheral keratitis of the left eye.


RESULTS
Serologic investigations for systemic disorders associated with vasculitic peripheral ulcerative keratitis were unremarkable. As the sclerokeratitis was thought to represent an ocular extension of the patient's cutaneous vasculitis, dapsone therapy was initiated and resulted in a rapid response of both the cutaneous and the ocular inflammation.


CONCLUSIONS
Erythema elevatum diutinum should be included in the differential diagnosis of vasculitic peripheral keratitis.
Aldave
Anthony J
AJ
Department of Ophthalmology, University of California, San Francisco/Francis I Proctor Foundation, San Francisco, California, USA. aldave@jsei.ucla.edu
Shih
Judy L
JL
Jovkar
Sayed
S
McLeod
Stephen D
SD
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004890:Erythema / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000188:drug therapy
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003622:Dapsone