A methodology to migrate the gene ontology to a description logic environment using DAML+OIL.
The Gene Ontology Next Generation Project (GONG) is developing a staged methodology to evolve the current representation of the Gene Ontology into DAML+OIL in order to take advantage of the richer formal expressiveness and the reasoning capabilities of the underlying description logic. Each stage provides a step level increase in formal explicit semantic content with a view to supporting validation, extension and multiple classification of the Gene Ontology. The paper introduces DAML+OIL and demonstrates the activity within each stage of the methodology and the functionality gained.
Wroe
C J
CJ
Department of Computer Science, University of Manchester, Oxford Rd, Manchester, M13 9PL, UK. cwroe@cs.man.ac.uk
Stevens
R
R
Goble
C A
CA
Ashburner
M
M
D002965:Classification; D019295:Computational Biology; D030562:Databases, Protein; D004798:Enzymes / Q000737:chemistry / Q000235:genetics; D023281:Genomics / Q000706:statistics & numerical data*; D016015:Logistic Models; D040901:Proteomics / Q000706:statistics & numerical data; D012984:Software; D009626:Terminology as Topic
D004798:Enzymes