title: Lithium target performance evaluation for low-energy accelerator-based in vivo measurements using gamma spectroscopy.
abstract: The operating conditions at McMaster KN Van de Graaf accelerator have been optimized to produce neutrons via the (7)Li(p, n)(7)Be reaction for in vivo neutron activation analysis. In a number of earlier studies (development of an accelerator based system for in vivo neutron activation analysis measurements of manganese in humans, Ph.D. Thesis, McMaster University, Hamilton, ON, Canada; Appl. Radiat. Isot. 53 (2000) 657; in vivo measurement of some trace elements in human Bone, Ph.D. Thesis. McMaster University, Hamilton, ON, Canada), a significant discrepancy between the experimental and the calculated neutron doses has been pointed out. The hypotheses formulated in the above references to explain the deviation of the experimental results from analytical calculations, have been tested experimentally. The performance of the lithium target for neutron production has been evaluated by measuring the (7)Be activity produced as a result of (p, n) interaction with (7)Li. In contradiction to the formulated hypotheses, lithium target performance was found to be mainly affected by inefficient target cooling and the presence of oxides layer on target surface. An appropriate choice of these parameters resulted in neutron yields same as predicated by analytical calculations.
authors.affiliation: Medical Physics and Applied Radiation Sciences Unit, McMaster University, Nuclear Research Building, Hamilton, ON, Canada L8S 4M1. aslam@mcmaster.ca
authors.lastname: Aslam
authors.forename: W V
authors.initials: WV
authors.lastname: Prestwich
authors.forename: F E
authors.initials: FE
authors.lastname: McNeill
mesh_terms: D006801:Humans; D008094:Lithium / Q000737:chemistry*; D009501:Neutron Activation Analysis; D009502:Neutrons; D013057:Spectrum Analysis / Q000379:methods*
chemical_list: D008094:Lithium