Aptamer structures: a preview into regulatory pathways?
The crystal structure of a streptomycin binding RNA aptamer displays a novel bipartite fold able to clamp the antibiotic. In view of the recent findings that metabolites directly control mRNA translation, we might expect that similar structures exist in natural RNAs.
Piganeau
Nicolas
N
Institute of Microbiology and Genetics, Vienna Biocenter, Dr. Bohrgasse 9/4, A-1030 Vienna, Austria.
Schroeder
Renée
R
D001665:Binding Sites; D003460:Crystallization; D009690:Nucleic Acid Conformation; D014176:Protein Biosynthesis; D012313:RNA / Q000737:chemistry* / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D013307:Streptomycin / Q000378:metabolism
D012333:RNA, Messenger; D012313:RNA; D013307:Streptomycin