Silica-related rheumatoid arthritis without lung involvement.
We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of silicosis. To our knowledge, this is the first report of silicosis apparent solely in the mediastinal lymph node of an RA patient. This suggests that lung involvement is not crucial for the development of silica-related arthritis.
Markovits
D
D
The B. Shine Department of Rheumatology, Rambam Medical Center, Haifa, 31096 Israel. d_markovits@rambam.health.gov.il
Schapira
D
D
Wiener
A
A
Nahir
A M
AM
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D008168:Lung / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000209:etiology / Q000473:pathology; D008297:Male; D008482:Mediastinum; D012720:Severity of Illness Index; D012829:Silicosis / Q000150:complications* / Q000473:pathology*