title: [The apoptosis in damaged testicular tissue caused by varicocele].
abstract: OBJECTIVE
  To investigate the effects of experimental varicocele on apoptosis of spermatogenic cells in rats.
  
  
  METHODS
  Experimental varicocele was induced by partial ligation of the left renal vein in Wistar rat. Apoptosis cells were detected by in situ terminal deoxynucleotityl transferase-mediated dTUP nick end labeling(TUNEL) technique.
  
  
  RESULTS
  There was certain proportion of apoptosis cells in spermatogenic cells in control group rats. The incidence of apoptosis increased remarkably in experimental group, the testicular growth was slower than that in control group.
  
  
  CONCLUSIONS
  The apoptosis of spermatogenic cells caused by varicocele may play an important role in leading to subfertility.
authors.affiliation: Department of Urology, Renmin Hospital, Wuhan University, Wuhan, Hubei 430060, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Xia
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000818:Animals; D017209:Apoptosis; D020287:In Situ Nick-End Labeling; D008297:Male; D009929:Organ Size; D051381:Rats; D017208:Rats, Wistar; D013733:Testicular Diseases / Q000209:etiology / Q000473:pathology; D013737:Testis / Q000473:pathology*; D014646:Varicocele / Q000150:complications / Q000503:physiopathology*