title: [The influence of two implant materials on the growth of three subgingival predominant bacteria].
abstract: OBJECTIVE
  Commercially pure titanium and titanium alloy as dental implants have show impressive clinical results. Despite the high success rates, some implants do fail. Compared to those studies on osseointegration of implants, the information pertaining to their failure is little. Further studies on the relationship between implant material and micro-organism are needed. The purpose of this investigation is to study the effect of two commonly used implant materials Titanium (TA2) and Ti-6AI-4V alloy (TC4) on the growth behaviour of three subgingival predominant bacteria Streptococcus sanguis (S. s), Porphyromanus gingivalis (P. g), Fusobacterium nucleatum (F. n) and their mixture.
  
  
  METHODS
  Under anaerobic condition, bacterial suspensions of S.s, P.g, F.n and their mixture were incubated together with the two implant materials respectively, setting the same bacterial suspensions as controls. After 2, 7 and 14 days, the bacterial growth amount was assayed by means of clone forming unit (CFU) method. The pH value of the bacterial suspension was determined by pH-Meter.
  
  
  RESULTS
  The results showed that there was no difference in amount of bacterial growth or pH value between TA2 group and TC4 group (P > 0.05). There was also no statistically significant change as to the proportion of individual bacteria in bacterial mixture or the pH value of culture suspension.
  
  
  CONCLUSIONS
  Under the condition of this investigation, the two studies implant materials have no examined influences on the growth of the subgingival bacteria and the pH value of their culture environment.
authors.affiliation: Department of Prosthodontics, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Gao
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Xiao
authors.forename: Feng
authors.initials: F
authors.lastname: Chai
authors.forename: Suqin
authors.initials: S
authors.lastname: Xian
authors.forename: Zhu
authors.initials: Z
authors.lastname: Zhu
authors.forename: Yurong
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000497:Alloys; D003470:Culture Media; D015921:Dental Implants / Q000382:microbiology*; D003764:Dental Materials; D016967:Fusobacterium nucleatum / Q000254:growth & development; D006801:Humans; D006863:Hydrogen-Ion Concentration; D016966:Porphyromonas gingivalis / Q000254:growth & development*; D013298:Streptococcus sanguis / Q000254:growth & development*; D014025:Titanium
chemical_list: D000497:Alloys; D003470:Culture Media; D015921:Dental Implants; D003764:Dental Materials; C031462:titanium alloy (TiAl6V4); D014025:Titanium