title: The first preparation of beta-lactones by radical cyclization.
abstract: beta-Lactones have, for the first time, been prepared by 4-exo-trig radical cyclization. Thus, alpha-ethenoyloxy radicals react in the presence of tributylstannane in a photothermal process to give beta-lactones. Highest yields were obtained when groups capable of stabilizing a carbon-centered radical were present at the 3-position of the alkenoate acceptor.
authors.affiliation: Department of Chemistry, University of Reading, Reading RG6 6AD, UK.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Castle
authors.forename: Chee-San
authors.initials: CS
authors.lastname: Hau
authors.forename: J B
authors.initials: JB
authors.lastname: Sweeney
authors.forename: Craig
authors.initials: C
authors.lastname: Tindall