[Current views on the pathogenesis of atherosclerosis from the position of infectious pathology].
The role of immune inflammation at atherogenesis is studied in the paper. Two etiological factors of atherosclerosis pathogeny are under examination: the role of modified low density lipoproteins (mLDL) and essential parasites (Chlamydia pneumoniae and Cytomegaloviruses). Generality of immune response during persistent infection into a blood vessel wall and deposit or formation of mLDL are discussed. The point of view is substantiated that the development of atherosclerotic damages of blood vessels is speeded up by a combination of the two mentioned etiological factors.
Nagornev
V A
VA
Pigarevskiĭ
P V
PV
Voskan'iants
A N
AN
Iakovleva
O A
OA
Mal'tseva
S V
SV
D000818:Animals; D001011:Aorta / Q000382:microbiology* / Q000821:virology; D002339:Carotid Arteries / Q000382:microbiology* / Q000821:virology; D003324:Coronary Artery Disease / Q000150:complications* / Q000382:microbiology* / Q000821:virology