[Human pasteurellosis: diagnosis, treatment and precautions].
The circumstances of diagnosis of human pasteurellosis are reviewed. The diagnosis is usually suspected for animal bite or scratch wounds. Conversely, in other infections the diagnosis is only based on bacteriological data. Phenotypic misidentification of Pasteurellaceae from clinical material is common. The phenotypic criteria of identification of the six species of human pathogen Pasteurella are presented. We emphasise that bite wound specimens have to be cultured for aerobic and anaerobic bacteria and yield an average of 5 bacterial isolates per culture. Antibiotic therapy relies upon amino-penicillins or cephalosporins, although b-lactamase producing strains are scarce. Fluoroquinolones can be an alternative for systemic infections. Molecular typing unequivocally points out the risk of transmission from pets to humans. Immunocompromised persons have to be made aware of precautions.
Gautier-Lerestif
A-L
AL
Laboratoire de bactériologie-virologie, CHRU Pontchaillou, rue Henri Le Guilloux, 35033 Rennes cedex 9.
Desbordes
L
L
Gaillot
O
O
Avril
J-L
JL
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001733:Bites and Stings; D003937:Diagnosis, Differential; D006801:Humans; D010325:Pasteurella / Q000302:isolation & purification / Q000472:pathogenicity; D010326:Pasteurella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control
D000900:Anti-Bacterial Agents