New chemical syntheses of cholest-4,6-dien-3-one.
Steroidal dienones represent a significant class of compounds that are useful intermediates in the further functionalization of the steroid nucleus. Their chemical synthesis can be problematic owing to the lack of a simplified method of preparation and the occurrence of impurities that can be difficult to remove. We have endeavored to develop new methods of chemical synthesis of cholest-4,6-dien-3-one that would yield a product of high purity.
Parish
Edward J
EJ
Department of Chemistry, Auburn University, Alabama 36849-5312, USA. parisej@auburn.edu
Sun
Hang
H
Lu
Ding
D
Kizito
Stephen A
SA
Qiu
Zhihai
Z
D002783:Cholestenones / Q000138:chemical synthesis* / Q000737:chemistry; D013256:Steroids / Q000138:chemical synthesis*
D002783:Cholestenones; D013256:Steroids; C030311:4,6-cholestadien-3-one