Prostatic involvement of a testicular lymphoma in a patient with myasthenia gravis on long-term azathioprine.
Side effects of long-term use of azathioprine in myasthenia gravis are infrequently reported. We present a patient who developed non-Hodgkin's lymphoma after eight years of azathioprine treatment for myasthenia gravis. He presented unusually with testicular lymphoma spreading to the prostate and the illness followed a particularly aggressive course.
Barthelmes
L
L
Department of Urology, Alaw Unit, Ysbyty Gwynedd, Bangor LL 57 2 PW Wales, UK.
Thomas
K J
KJ
Seale
J R C
JR
D001379:Azathioprine / Q000009:adverse effects*; D017809:Fatal Outcome; D006801:Humans; D016393:Lymphoma, B-Cell / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011471:Prostatic Neoplasms; D013736:Testicular Neoplasms / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology*; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000601:surgery
D001379:Azathioprine