Future strategies in psychiatric genetics.
There is evidence suggesting that the primary (idiopathic) mental disorders are due to epimutations involving genes that determine the structure of the brain. Although in the past it has been suggested that the genes underlying the primary mental disorders may be unidentifiable, recent developments in neuroscience suggest otherwise. This paper outlines various epigenetic strategies that may help identify the genes underlying these disorders.
Peedicayil
Jacob
J
Department of Pharmacology, Christian Medical College and Hospital, Vellore, India. jpeedicayil@hotmail.com
D019175:DNA Methylation; D015870:Gene Expression; D006657:Histones / Q000378:metabolism; D006801:Humans; D001523:Mental Disorders / Q000235:genetics*; D009154:Mutation
D006657:Histones