title: Epithelial ingrowth in a phakic corneal transplant patient after traumatic wound dehiscence.
abstract: OBJECTIVE
  To report a case of epithelial ingrowth (downgrowth) occurring in a phakic corneal transplant patient after traumatic wound dehiscence with iris prolapse that was successfully eradicated with early surgical intervention.
  
  
  METHODS
  Interventional case report of a 70-year-old monocular, phakic patient who developed epithelial ingrowth within 1 week of repair of a traumatic penetrating keratoplasty wound dehiscence, with reposition of the iris that had been prolapsed for 36 hours. A gradually expanding membrane developed from the surface of the reposited iris, across the anterior lens capsule. Argon laser photocoagulation applied to the surface of the iris confirmed the diagnosis and outlined the extent of the epithelial tissue on the iris.
  
  
  RESULTS
  Intraoperative peeling of the epithelial membrane from the surface of the lens and excision of the involved iris were performed combined with extracapsular cataract extraction and insertion of a posterior chamber intraocular lens via an open-sky technique through a repeat penetrating keratoplasty opening in the cornea. This resulted in complete resolution of the intraocular epithelialization. Histopathologic examination of the excised tissue confirmed the diagnosis of epithelial ingrowth.
  
  
  CONCLUSIONS
  Reposition of traumatically prolapsed iris tissue can result in epithelial ingrowth. Early aggressive surgical intervention can successfully remove all the epithelial tissue from within the anterior segment.
authors.affiliation: Cornea Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA.
authors.forename: Parveen K
authors.initials: PK
authors.lastname: Nagra
authors.forename: Irving M
authors.initials: IM
authors.lastname: Raber
mesh_terms: D000368:Aged; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D004847:Epithelial Cells / Q000473:pathology; D019573:Epithelium, Corneal / Q000473:pathology*; D005131:Eye Injuries / Q000150:complications*; D006801:Humans; D007499:Iris Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D015948:Keratoplasty, Penetrating; D008297:Male; D011391:Prolapse; D013529:Surgical Wound Dehiscence / Q000150:complications*; D014949:Wounds, Nonpenetrating / Q000150:complications*