title: [Renal involvement in Behçet's disease. About six cases].
abstract: OBJECTIVE
  To analyze anatomoclinic and evolutive aspects of the renal involvement associated to the Behçet's disease through 6 observations collected in the nephrology department from 1985 to 2000 and to make a review of the literature.
  
  
  METHODS
  Retrospective study, diagnosis of Behçet's disease according to the Classification of the International Group Study on the Behçet's disease and renal damage confirmed by histology.
  
  
  RESULTS
  Our patients all male are aged between 25 to 55 years with a mean at 34 years old. The renal damage was revelated by a nephrotic syndrome in 3 cases and by a proteinuria at 1 to 2.7 g/day in 3 cases. Microscopic hematuria was present in 2 cases and arterial hypertension in 2 cases. The renal insufficiency has been noted in 2 cases of which severe in one of them. The renal biopsy showed an amyloidosis AA type in 3 cases, a segmental and focal glomerulonephritis in 2 cases and a thrombotic microangiopathy associated to a moderate tubulo-interstitiel lesions by toxicity of ciclosporine in 1 case. The extrarenal signs were dominated by bipolar aphtosis in all cases, necrotic pseudofolliculitis and the no specific cutaneous hyperreactivity in 5 cases and the erythema nodosum in 1 case. The ocular manifestation has been noted in 4 cases and articular manifestation in 3 cases. The vascular manifestation has been noted in one case. The treatment was colchicine in 4 cases and prednisone and cyclophosphamide in 1 case. Three patients were lost of view and a patient died in hemodialysis. The 2 other patients with amylosis had persistent proteinuria with a normal renal function.
  
  
  CONCLUSIONS
  The kidney is one of organs that can alter the prognosis of the Behçet's disease; so, its screening must be realised in each patient with this disease.
authors.affiliation: Service de néphrologie, CHU Ibn Rochd, Casablanca, Maroc. khalid_zahiri@yahoo.fr
authors.forename: K
authors.initials: K
authors.lastname: Zahiri
authors.forename: K
authors.initials: K
authors.lastname: Hachim
authors.forename: A
authors.initials: A
authors.lastname: Zamd
authors.forename: E
authors.initials: E
authors.lastname: Fatihi
authors.forename: M-G
authors.initials: MG
authors.lastname: Benghanem
authors.forename: B
authors.initials: B
authors.lastname: Ramdani
authors.forename: S
authors.initials: S
authors.lastname: Sqalli
authors.forename: D
authors.initials: D
authors.lastname: Zaïd
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D001706:Biopsy; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D051437:Renal Insufficiency / Q000209:etiology; D012189:Retrospective Studies