[An immunohistochemical study on the distribution in organs in cases with morphine poisoning].
OBJECTIVE
To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection.


METHODS
Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method.


RESULTS
Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found.


CONCLUSIONS
The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.
Shan
Ya-ming
YM
Shenyang Criminal Science and Technology Institute, Shenyang 110002.
Hao
Chun-yu
CY
Wang
Long
L
D000328:Adult; D001921:Brain / Q000378:metabolism*; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D007150:Immunohistochemistry; D007668:Kidney / Q000378:metabolism; D008297:Male; D009020:Morphine / Q000493:pharmacokinetics* / Q000506:poisoning*; D009021:Morphine Dependence / Q000378:metabolism; D014018:Tissue Distribution
D009020:Morphine