High frequency of novel germline mutations in the VHL gene in the heterogeneous population of Brazil.
Rocha
J C C
JC
Department of Oncogenetics, Hospital do Câncer A C Camargo, São Paulo, Brazil. jccrocha@ludwig.org.br
Silva
R L A
RL
Mendonça
B B
BB
Marui
S
S
Simpson
A J G
AJ
Camargo
A A
AA
D001938:Brazil; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004252:DNA Mutational Analysis; D005192:Family Health; D005787:Gene Frequency; D005838:Genotype; D018095:Germ-Line Mutation; D006801:Humans; D008025:Ligases / Q000235:genetics*; D010641:Phenotype; D025521:Tumor Suppressor Proteins; D044767:Ubiquitin-Protein Ligases; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D006623:von Hippel-Lindau Disease / Q000235:genetics* / Q000473:pathology
D025521:Tumor Suppressor Proteins; D004247:DNA; D044767:Ubiquitin-Protein Ligases; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D008025:Ligases; C497446:VHL protein, human