title: CT colonography: digital subtraction bowel cleansing with mucosal reconstruction initial observations.
abstract: The authors evaluated a computed tomography (CT) colonographic technique with a combination of preexamination orally ingested positive contrast material and postacquisition image processing to subtract out the ingested opacified bowel contents. With this technique, rigorous physical purging of the bowel was not necessary before structural examination of the colon. With images obtained in 20 patients, two readers were able to correctly identify the majority of polyps confirmed at colonoscopy. Their performance for detection of lesions larger than 1 cm was similar to that with conventional CT colonography.
authors.affiliation: Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA. mzalis@partners.org
authors.forename: Michael E
authors.initials: ME
authors.lastname: Zalis
authors.forename: James
authors.initials: J
authors.lastname: Perumpillichira
authors.forename: Chiara
authors.initials: C
authors.lastname: Del Frate
authors.forename: Peter F
authors.initials: PF
authors.lastname: Hahn
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000465:Algorithms; D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic / Q000379:methods*; D003287:Contrast Media / Q000008:administration & dosage; D004573:Electrolytes / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000008:administration & dosage; D012680:Sensitivity and Specificity; D013382:Subtraction Technique
chemical_list: D003287:Contrast Media; D004573:Electrolytes; C033608:Golytely; D011092:Polyethylene Glycols