title: Antifeedant and growth inhibitory effects of some neo-clerodane diterpenoids isolated from Clerodendron species (Verbenaceae) on Earias vitella and Spodoptera litura.
abstract: Antifeedant and growth inhibitory effects of various neo-clerodane diterpenoids having a furofuran moiety, isolated from Clerodendron spp., were studied using Earias vitella and Spodoptera litura. The compounds clerodendrin B, 3-epicaryoptin, 15-hydroxyepicaryoptin, and clerodin were effective antifeedants at 10 microg/cm(3) (30 microg/g) of diet against E. vitella and at 10 microg/cm(2) of leaf against S. litura. All of the tested compounds, namely, clerodendrin B, 3-epicaryoptin, clerodendrin C, 15-hydroxyepicaryoptin, clerodendrin B acetate, and clerodin, showed good insect growth inhibitory activity even at lower concentrations.
authors.affiliation: T. R. Govindachari Centre for Natural Products, SPIC Science Foundation, 88 Mount Road, Chennai 600 032, India. gnkrishna@hotmail.com
authors.forename: G N
authors.initials: GN
authors.lastname: Krishna Kumari
authors.forename: J
authors.initials: J
authors.lastname: Balachandran
authors.forename: S
authors.initials: S
authors.lastname: Aravind
authors.forename: M R
authors.initials: MR
authors.lastname: Ganesh
mesh_terms: D000818:Animals; D032409:Clerodendrum / Q000737:chemistry*; D004224:Diterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D045785:Diterpenes, Clerodane; D004435:Eating / Q000187:drug effects; D007306:Insecticides / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D009036:Moths / Q000254:growth & development / Q000502:physiology*; D018411:Spodoptera / Q000254:growth & development / Q000502:physiology*
chemical_list: D004224:Diterpenes; D045785:Diterpenes, Clerodane; D007306:Insecticides; C468586:neoclerodane