title: Health-related quality of life after maxillectomy: a comparison between prosthetic obturation and free flap.
abstract: OBJECTIVE
  The purpose of this cross sectional study was to evaluate the health-related quality of life of patients following maxillectomy and to compare obturation and free flap reconstruction.
  
  
  METHODS
  At the Regional Maxillofacial Unit in Liverpool, United Kingdom, between 1992 to 1996, 39 patients underwent maxillectomy for malignant pathology. Of these patients, 28 (10 underwent obturation and 18 underwent free tissue reconstruction) completed a postoperative semi-structured interview. Eight questionnaires were used to test aspects of health-related quality of life and function.
  
  
  RESULTS
  The main findings were the associations between the size of maxillectomy defect and the University of Washington activity (-0.53; P =.005) and recreation (-0.70; P <.001) domains, and with the physical functioning (-0.58; P =.001) and quality of life (-0.51; P =.007) domains of the European Organization for Research and Treatment of Cancer questionnaire. No statistically significant differences were seen between the obturator and free flap groups. Borderline trends were for obturator patients to be more concerned about their appearance, to have more pain and soreness in their mouths, to be more aware of their upper teeth, more self-conscious and less satisfied with their upper dentures, and less satisfied with function.
  
  
  CONCLUSIONS
  Similar subjective outcomes were found for both groups, and a larger longitudinal study is needed to test these relationships more rigorously.
authors.affiliation: Regional Maxillofacial Unit, University Hospital Aintree, Aintree Trust, Liverpool, United Kingdom. snrogers@globalnet.co.uk
authors.forename: Simon N
authors.initials: SN
authors.lastname: Rogers
authors.forename: Derek
authors.initials: D
authors.lastname: Lowe
authors.forename: Deborah
authors.initials: D
authors.lastname: McNally
authors.forename: James S
authors.initials: JS
authors.lastname: Brown
authors.forename: E David
authors.initials: ED
authors.lastname: Vaughan
mesh_terms: D000368:Aged; D016025:Bone Transplantation / Q000523:psychology; D003430:Cross-Sectional Studies; D005205:Fascia / Q000637:transplantation; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008441:Maxillary Neoplasms / Q000601:surgery; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation; D019647:Oral Surgical Procedures / Q000523:psychology*; D010158:Palatal Obturators / Q000523:psychology*; D017060:Patient Satisfaction; D010865:Pilot Projects; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000523:psychology*; D013524:Surgical Flaps; D011795:Surveys and Questionnaires