title: [Calcimimetics as a new chance for effective treatment of calcium metabolism disturbances].
abstract: Physiological principles are presented of calcium receptor (CaR) as well as agents affecting the receptor, defined as calcimimetics. Positive influence of type 1 and type 2 calcimimetics on calcium metabolism is discussed. The clinical indications for calcimimetics, especially type 2, in the future, seem to be hypercalcemia in the course of primary and secondary hyperparathyroidism as well as hypercalcemia in patients with parathyroid carcinoma.
authors.affiliation: Klinika Nefrologii ze Stacja Dializ Centralnego Szpitala Klinicznego WAM w Warszawie.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Nowak
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Laudański
mesh_terms: D002118:Calcium / Q000819:agonists* / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy; D007668:Kidney / Q000378:metabolism; D010280:Parathyroid Glands / Q000378:metabolism; D010282:Parathyroid Neoplasms / Q000188:drug therapy; D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface / Q000187:drug effects*
chemical_list: D002135:Calcium-Binding Proteins; D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface; D002118:Calcium