title: Neurotrophin-4 mediated TrkB activation reinforces morphine-induced analgesia.
authors.affiliation: Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Lucas
authors.forename: Panu
authors.initials: P
authors.lastname: Hendolin
authors.forename: Tibor
authors.initials: T
authors.lastname: Harkany
authors.forename: Karin
authors.initials: K
authors.lastname: Agerman
authors.forename: Gustavo
authors.initials: G
authors.lastname: Paratcha
authors.forename: Carl
authors.initials: C
authors.lastname: Holmgren
authors.forename: Yuri
authors.initials: Y
authors.lastname: Zilberter
authors.forename: Mikko
authors.initials: M
authors.lastname: Sairanen
authors.forename: Liliana
authors.initials: L
authors.lastname: Minichiello
authors.forename: Eero
authors.initials: E
authors.lastname: Castren
authors.forename: Patrik
authors.initials: P
authors.lastname: Ernfors
mesh_terms: D000698:Analgesia; D000701:Analgesics, Opioid / Q000494:pharmacology; D000818:Animals; D001933:Brain Stem / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005799:Genes, Dominant; D066298:In Vitro Techniques; D008125:Locus Coeruleus / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D009020:Morphine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D009270:Naloxone / Q000494:pharmacology; D009414:Nerve Growth Factors / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D010147:Pain Measurement / Q000187:drug effects; D010766:Phosphorylation / Q000187:drug effects; D020813:Receptor, trkB / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D017450:Receptors, Opioid, mu / Q000378:metabolism; D014279:Trigeminal Nucleus, Spinal / Q000187:drug effects / Q000378:metabolism
chemical_list: D000701:Analgesics, Opioid; D009414:Nerve Growth Factors; D017450:Receptors, Opioid, mu; D009270:Naloxone; D009020:Morphine; D020813:Receptor, trkB; C073922:neurotrophin 4