title: [Cryotherapy with nitrous oxide in primary care].
abstract: OBJECTIVE
  To study the efficacy, tolerance and safety in primary care of the cryotherapy technique using nitrous oxide. Design. Descriptive, observational and transversal study.
  
  
  METHODS
  Mariñamansa-A Cuña Health Centre, Ourense.
  
  
  METHODS
  All the patients who consulted for cutaneous lesions caused by cryotherapy between March and April 2000 (n=130).
  
  
  METHODS
  Age, sex, diagnosis, location, size of lesion, duration of application of the cryogenic agent, previous treatment, side-effects observed, and evolution of the lesion.
  
  
  RESULTS
  Mean age was 36.65 (95% CI, 32.57-40.74), of whom 53.8% (95% CI, 44.80-62.50) were women. The most common lesions were common warts (68.5%), actinic Keratosis (12.3%) and plantar warts (7.7%). We found that most lesions were located on an upper limb (50.8%). The mean size of lesions was 8.65 mm2 (95% CI, 4.50-12.80). 69.7% of warts were scraped prior to cryotherapy; and 16.2% received prior keratolysis. We found no side-effects in 32.3% of the patients; the commonest side-effect detected was blisters. Mean number of cryotherapy sessions was 2.82 (95% CI, 2.39-3.29). The technique was tolerated well in 83.8% of cases. We found total cure in 87.7%. Most of the cutaneous lesions that failed were common warts.
  
  
  CONCLUSIONS
  Nitrous oxide is effective in most lesions caused by cryotherapy. The technique is tolerated well, can be handled easily and can be used in primary care.
authors.affiliation: Centro de Saúde Mariñamansa-A Cuña. Servicio Galego de Saúde. Ourense. España. carmevill@eresmas.com
authors.forename: C
authors.initials: C
authors.lastname: Menéndez Villalva
authors.forename: T
authors.initials: T
authors.lastname: Gamarra Mondelo
authors.forename: R
authors.initials: R
authors.lastname: Fernández Alvarez
authors.forename: C
authors.initials: C
authors.lastname: Núñez Losada
authors.forename: M
authors.initials: M
authors.lastname: Pérez García
authors.forename: S
authors.initials: S
authors.lastname: Bujan Garmendia
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D017679:Cryotherapy; D005260:Female; D006801:Humans; D008297:Male; D009609:Nitrous Oxide; D011320:Primary Health Care; D012871:Skin Diseases / Q000628:therapy*
chemical_list: D009609:Nitrous Oxide