Excision and integration of cassettes by an integron integrase of Nitrosomonas europaea.
We found in the environmental strain Nitrosomonas europaea a chromosomal integron-like structure with an integrase gene, intI(Neu). We have tested the capacity of the IntINeu integrase to excise and integrate several resistance gene cassettes. The results allow us to consider IntINeu a new functional integron integrase.
Léon
Grégory
G
Centre de Recherche en Infectiologie, Centre Hospitalier Universitaire de Québec, Québec, Canada.
Roy
Paul H
PH
D001287:Attachment Sites, Microbiological; D001483:Base Sequence; D024881:Drug Resistance, Bacterial / Q000235:genetics; D019426:Integrases / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D009606:Nitrosomonas / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D010802:Phylogeny; D010957:Plasmids; D016133:Polymerase Chain Reaction; D011995:Recombination, Genetic; D016415:Sequence Alignment
D019426:Integrases; C115006:integron integrase IntI1