title: [Sex correction in testicular feminization syndrome].
abstract: From 1993 to 2000 the authors observed 10 patients with testicular feminization. In spite of existent highly informative methods, early diagnosis of the genesis of abnormal sexual differentiation is not easy, it requires time. Treatment policy varied with the form of testicular feminization. In a complete form (6 patients), bilateral ventrofixation of the gonads (ovotestis) was made, in incomplete form (4 patients) male gonads were removed with subsequent replacement hormonotherapy. Correction of the external genitalia consisted in amputation of the hypertrophic clitoris with creation of the female-type external genitalia. It is emphasized that in incomplete testicular feminization surgical correction should be started before the appearance of secondary sexual characters to raise effectiveness of hormone treatment in formation of a female genotype.
authors.forename: M D
authors.initials: MD
authors.lastname: Dzhavad-Zade
authors.forename: E Ia
authors.initials: EIa
authors.lastname: Guseĭnov
authors.forename: T T
authors.initials: TT
authors.lastname: Guseĭnova
authors.forename: A D
authors.initials: AD
authors.lastname: Magarramov
mesh_terms: D000293:Adolescent; D000367:Age Factors; D013734:Androgen-Insensitivity Syndrome / Q000175:diagnosis / Q000235:genetics / Q000601:surgery*; D002648:Child; D004967:Estrogens / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D011182:Postoperative Care; D013997:Time Factors
chemical_list: D004967:Estrogens