title: [A patient with stage IVb small cell carcinoma of the esophagus who survived 23 months after systemic cancer chemotherapy].
abstract: A 59-year-old male visited our hospital with complaints of difficulty in swallowing. X-ray barium studies and upper gastrointestinal endoscopic examination revealed an irregular ulcerated lesion in the lower portion of the esophagus, which was diagnosed based on pathology tests as small cell carcinoma. A computed tomography scan showed para-aortic lymph node swelling and multiple liver metastases. Treatment with chemotherapy of CDDP and 5-FU showed clinical complete remission. However, the patient died of paraaortic lymph node metastasis, recurrence of the original lesion, multiple liver metastasis and brain metastasis 23 months after diagnosis. The prognosis of small cell carcinoma of the esophagus is quite unfavorable because of the highly aggressive biological behavior. However, if remission is achieved by chemotherapy as in this case, a better prognosis is possible.
authors.affiliation: Dept. of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University.
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsujie
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Shibata
authors.forename: Takashi
authors.initials: T
authors.lastname: Nomura
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Tanaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Morimoto
authors.forename: Syoichi
authors.initials: S
authors.lastname: Fujita
authors.forename: Kotaro
authors.initials: K
authors.lastname: Kitani
authors.forename: Shin
authors.initials: S
authors.lastname: Nakahira
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okuda
authors.forename: Masashi
authors.initials: M
authors.lastname: Takeda
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D005047:Etoposide / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017741:Survivors
chemical_list: D005047:Etoposide; D002945:Cisplatin; D005472:Fluorouracil