title: Olanzapine treatment of anorexia nervosa: a retrospective study.
abstract: BACKGROUND
  Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non-eating-disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients.
  
  
  METHODS
  Eighteen AN subjects who engaged in open treatment with olanzapine were retrospectively questioned about their response.
  
  
  RESULTS
  Subjects reported a significant reduction in anxiety, difficulty eating, and core eating disorder symptoms after taking olanzapine.
  
  
  CONCLUSIONS
  These data lend support to the possibility that olanzapine may be useful in AN patients.
  
  
  CONCLUSIONS
  A controlled trial is necessary to prove that olanzapine is efficacious.
authors.affiliation: Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: Amanda
authors.initials: A
authors.lastname: Malina
authors.forename: Jill
authors.initials: J
authors.lastname: Gaskill
authors.forename: Claire
authors.initials: C
authors.lastname: McConaha
authors.forename: Guido K
authors.initials: GK
authors.lastname: Frank
authors.forename: Maria
authors.initials: M
authors.lastname: LaVia
authors.forename: Lisa
authors.initials: L
authors.lastname: Scholar
authors.forename: Walter H
authors.initials: WH
authors.lastname: Kaye
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000188:drug therapy*; D001569:Benzodiazepines; D006801:Humans; D000077152:Olanzapine; D010890:Pirenzepine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D012189:Retrospective Studies; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
chemical_list: D001569:Benzodiazepines; D000077152:Olanzapine; D010890:Pirenzepine; D017367:Selective Serotonin Reuptake Inhibitors