[Screening and hepatitis C management survey in general medicine in the Alpes-Maritimes and east Var area].
BACKGROUND
This study was performed to assess screening and management of hepatitis C by community-based practitioners in the Alpes Maritimes district in the South of France and to compare their practices with the recommendations issued by the consensus conferences in 1997 and 1999. This information was to be used to adapt continuing medical education to the needs of practitioners in the area.


METHODS
Two hundred and nineteen general practitioners who were members of eighteen continuing medical education associations accepted to complete a questionnaire containing eighteen closed questions. It was issued late 1999 during one of the monthly meetings and completed by all the participating physicians.


RESULTS
Only 32% of general practitioners knew the conclusions of one of the two French and European consensus conferences concerning hepatitis C. General practitioner practices were in accordance with recommendations for targeted screening in case of transfusion before 1991 (88%), intra-venous drug use (94%) and increased ALT (91%); however intra nasal drug use (35%) and imprisonment (46%) were underestimated risk factors. Frequency of screening was correlated to duration of practice (P<0.01), size of practice (P<0.02) and follow-up of hepatitis C infected patients, regardless of treatment (P<0.03). Upon discovery of a positive HCV status, 80% of general practitioners prescribed initial investigations but these included costly and needless procedures such as hepatic imaging (56%), RNA quantification (39%) and viral genotype (6%). On the other hand, 79% general practitioners recommended a liver biopsy for patients with elevated transaminase levels. When transaminase levels were normal, only 13% requested qualitative detection of viral RNA. Generally, general practitioners were confused concerning the indications for qualitative or quantitative viral RNA investigations. Few general practitioners followed treated HCV-infected patients and renewed interferon therapy prescriptions. Condom use was advised by 56% of GPs for couples in which one of the partners had a positive HCV status.


CONCLUSIONS
This study demonstrates the weak impact of consensus conferences on hepatitis C management for general practitioners in the Alpes Maritimes. It provides an opportunity to identify the need for specific training which will be developed within the Côte d'Azur Hepatitis C Network.
Ouzan
Denis
D
Institut Arnault Tzanck, St Laurent du Var. denis.ouzan@wanadoo.fr
Hofliger
Philippe
P
Cavailler
Philippe
P
Mamino
Christophe
C
Tran
Albert
A
D001706:Biopsy; D004796:Clinical Enzyme Tests; D004502:Education, Medical, Continuing; D005194:Family Practice / Q000193:education*; D005602:France; D019983:Guideline Adherence; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000473:pathology; D017410:Practice Guidelines as Topic; D012367:RNA, Viral / Q000032:analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires; D000637:Transaminases / Q000097:blood
D012367:RNA, Viral; D000637:Transaminases