title: Vitrectomy with silicone oil infusion in severe diabetic retinopathy.
abstract: OBJECTIVE
  To determine the results of pars plana vitrectomy (PPV) and silicone oil infusion (SOI) in severe proliferative diabetic retinopathy (PDR).
  
  
  METHODS
  The records of 23 eyes (21 patients: 12 males, nine females) with PDR who had undergone PPV and SOI were reviewed retrospectively.
  
  
  RESULTS
  Average follow up was 5.4 months (range 1-25). Surgical indications were tractional retinal detachment (TRD) (17.4%), traction-rhegmatogenous retinal detachment (TRRD) (8.7%), TRD with vitreous haemorrhage (VH) (48%), TRD with neovascular glaucoma (NVG) (8.6%), TRD with fibrinoid syndrome (FS) (17.3%). With one operation, the retinal reattachment rate was 17/23 (74%). Among these 23 eyes, 11 (48%) had previously failed vitrectomy, and the retina was attached in 8/11 (73%) with a single procedure. With additional surgery employing PPV and SOI, the final reattachment rate was 20/23 (87%). The only cases with intraocular pressure <5 mm Hg had retinal detachment. Postoperative visual acuity (VA) improved in 10 eyes (44%), was unchanged in three (12%), and decreased in 10 eyes (44%).
  
  
  CONCLUSIONS
  SO tamponade is useful in severely diseased eyes with PDR, even in the presence of rubeosis iridis (RI) and NVG, FS, or in cases with previously failed vitrectomy, especially in the presence of RI.
authors.affiliation: Institute of Ophthalmology and Visual Science, NJMS, UMDNJ, USA.
authors.forename: A
authors.initials: A
authors.lastname: Castellarin
authors.forename: R
authors.initials: R
authors.lastname: Grigorian
authors.forename: N
authors.initials: N
authors.lastname: Bhagat
authors.forename: L
authors.initials: L
authors.lastname: Del Priore
authors.forename: M A
authors.initials: MA
authors.lastname: Zarbin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy / Q000379:methods; D003930:Diabetic Retinopathy / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000150:complications / Q000601:surgery; D012189:Retrospective Studies; D012827:Silicone Oils / Q000008:administration & dosage*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000009:adverse effects / Q000379:methods*
chemical_list: D012827:Silicone Oils