Comparison of MR and PET imaging for the evaluation of liver metastases.
OBJECTIVE
To compare the accuracy of fluoro-18-deoxyglucose positron emission tomography (FDG-PET) and dynamic-enhanced magnetic resonance imaging (MRI) scans in the diagnosis of liver metastatic lesions from colon and other sources.


METHODS
Thirty consecutive patients with known or suspected metastatic lesions were scanned by both MRI and PET. Histopathology and/or clinical outcome, including cross-sectional imaging follow up, were used as a gold standard.


RESULTS
Of 30 patients, 16 were positive by pathology and/or clinical outcome and 14 were negative for liver metastases. The sensitivity, specificity, and positive and negative predictive values on MRI were 85.7%, 100%, 100%, and 89%, respectively, compared to 71%, 93.7%, 90.9%, and 79% on FDG-PET. The difference between the two methods was not significant (X(2) = 0.2, P > 0.05).


CONCLUSIONS
Our study showed no significant difference in detection of liver metastases using MRI or FDG-PET. However, MRI has advantages in spatial resolution and lesion characterization.
Yang
Ming
M
Department of Radiology, West Virginia University, School of Medicine, Morgantown, West Virginia 26505-9235, USA.
Martin
Diego R
DR
Karabulut
Nevzat
N
Frick
Mathis P
MP
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D008875:Middle Aged; D012189:Retrospective Studies; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed
D019788:Fluorodeoxyglucose F18