[Effect of droperidol and tramadol combination on the hemostasis in rabbits].
The effect of a combined administration of analgesic droperidol and neuroleptic tramadol (tramal) on the plasma coagulation and platelet aggregation was studied on awake rabbits. Both tramadol and droperidol, as well as their combination, enhance the coagulation of plasma proteins and suppress the thrombocyte deaggregation process.
Bol'shakov
V V
VV
Pharmacology Department, Kemerovo State Medical Academy, ul. Voroshilova 22A, Kemerovo, 650029 Russia.
Sapozhkov
A V
AV
Denisova
S V
SV
D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D000818:Animals; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004329:Droperidol / Q000008:administration & dosage / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006487:Hemostasis / Q000187:drug effects*; D008297:Male; D011817:Rabbits; D014147:Tramadol / Q000008:administration & dosage / Q000009:adverse effects*
D000701:Analgesics, Opioid; D014150:Antipsychotic Agents; D004338:Drug Combinations; D014147:Tramadol; D004329:Droperidol