title: Phase I/IIA randomized study of PHY906, a novel herbal agent, as a modulator of chemotherapy in patients with advanced colorectal cancer.
authors.affiliation: Department of Medicine, Yale Cancer Center, Yale University School of Medicine, West Haven, CT 06516, USA.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Farrell
authors.forename: Shivaani
authors.initials: S
authors.lastname: Kummar
mesh_terms: D000930:Antidiarrheals / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002166:Camptothecin / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000627:therapeutic use; D017321:Clinical Trials, Phase I as Topic; D017322:Clinical Trials, Phase II as Topic; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D003967:Diarrhea / Q000139:chemically induced* / Q000517:prevention & control*; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005472:Fluorouracil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D000077146:Irinotecan; D015337:Multicenter Studies as Topic; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D000930:Antidiarrheals; D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; C476037:PHY 906; D000077146:Irinotecan; D005472:Fluorouracil; D002166:Camptothecin