title: [The effect of interictal epileptiform discharges on cognitive function in children with idiopathic epilepsy].
abstract: BACKGROUND
  Transient cognitive disorders (CD) in benign rolandic epilepsy (BRE), the most common of idiopathic partial epilepsy (IPE), may be secondary to interictal epileptiform discharges (IED).
  
  
  OBJECTIVE
  To determine incidence and risk factors for persistent TC in students with IE before, during and after antiepileptic (AE).
  
  
  METHODS
  
  
  
  METHODS
  6 12 years old, IPE, controlled for 2 years with AE, and follow up for 5 years.
  
  
  METHODS
  intelligence (Wechsler III), learning (Wechsler), academic level (Woodcock Johnson) and attention/behavior (O Conners R).
  
  
  METHODS
  sex, age of onset, seizure type, interval between first seizure and AE onset, EEG results and AE type.
  
  
  METHODS
  chi square.
  
  
  RESULTS
  Fourteen children had decreased learning and attention span with impulsivity, hyperactivity, low tolerance and agressivity during remission; 12 (85,71%) with temporal lobe epilepsy: 6 (50%) with IED in the left dominant hemisphere, 2 (16,67%) with IED in the right temporal lobe in left dominant hemisphere children, 2 (16,67%) in both temporal lobes in left dominant hemisphere children and 2 (14,29%) with ERB and IED. MRI were normal.
  
  
  CONCLUSIONS
  Children with idiopathic temporal lobe epilepsy and IED in the left dominant hemisphere are at higher risk for CD than children with other types of IPE. To control the seizures and to abolish the IED are recommended in an attempt to prevent these cognitive disorders
authors.affiliation: Departamento de Neurology, Miami Children's Hospital, Miami, FL 331555, USA.
authors.forename: O
authors.initials: O
authors.lastname: Papazian
authors.forename: I
authors.initials: I
authors.lastname: Alfonso
authors.forename: V
authors.initials: V
authors.lastname: García-Galarreta
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D003072:Cognition Disorders / Q000209:etiology* / Q000503:physiopathology; D004569:Electroencephalography; D019305:Epilepsy, Rolandic / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors
chemical_list: D000927:Anticonvulsants