Direct Zn-diamine promoted reduction of C=O and C=N bonds by polymethylhydrosiloxane in methanol.
Ketones and imines are chemoselectively reduced at room temperature in methanol to the corresponding alcohols and amines in high yields in a one-step procedure using polymethylhydrosiloxane (PMHS) and a simple zinc-diamine catalyst.
Bette
Virginie
V
Chimie Organique Appliquée, UPRESA 8010 CNRS-Université de Lille 1, ENSCL, BP 108, 59652 Villeneuve d'Ascq Cedex, France.
Mortreux
André
A
Lehmann
Christian W
CW
Carpentier
Jean-François
JF