Primary hyperparathyroidism, hypercalcemic crisis and subsequent seizures occurring during pregnancy: a case report.
A first-trimester primigravid patient presented with hyperemesis and malaise. Work-up was consistent with primary hyperparathryoidism. During acute treatment, she developed generalized motor seizures considered to be secondary to hypercalcemia. Evaluation and treatment of women with primary hyperparathyroidism and hypercalcemia are reviewed, and the pathogenesis of seizures associated with hypercalcemia is discussed.
Cherry
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TA
Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center at Amarillo, Amarillo, Texas 79106, USA.
Kauffman
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RP
Myles
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TD
D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D020073:Gravidity; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology* / Q000628:therapy; D006939:Hyperemesis Gravidarum / Q000209:etiology; D006961:Hyperparathyroidism / Q000209:etiology* / Q000601:surgery; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016105:Parathyroidectomy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011261:Pregnancy Trimester, First; D012640:Seizures / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome
D000927:Anticonvulsants; D010281:Parathyroid Hormone