Body fat mass in hemodialysis patients.
BACKGROUND
Changes in body fat mass in a large number of hemodialysis patients is unknown.


METHODS
Body fat mass and lean body mass were measured by dual x-ray absorptiometry (DXA) in 561 patients with hemodialysis duration less than 180 months (62.3 +/- 11.5 years old; mean +/- SD).


RESULTS
Fat mass tended to increase during the first 3 years of hemodialysis, and it tended to decrease thereafter. Between hemodialysis duration and the fat mass index, there was a significant positive correlation within the first 36-month period of hemodialysis (r = 0.124; P < 0.05; n = 245), and a significant negative correlation during the period of 36 to 180 months. (r = -0.192; P < 0.001; n = 316). There was no tendency of change in the lean body mass index.


CONCLUSIONS
Considering the results together with the authors previous prospective study results, which show significant fat mass increase in the first year of hemodialysis, the present cross-sectional study may suggest that fat mass gradually increases in the first 3 years and decreases thereafter. Fat mass is suggested to be a nutritional parameter in hemodialysis patients.
Ishimura
Eiji
E
Department of Nephrology, Osaka City University Graduate School of Medicine and Shirasagi Hospital Kidney Center, Osaka, Japan. ish@med.osaka-cu.ac.jp
Okuno
Senji
S
Marukawa
Taro
T
Katoh
Yoshikazu
Y
Hiranaka
Toshiyuki
T
Yamakawa
Tomoyuki
T
Morii
Hirotoshi
H
Kim
Masao
M
Matsumoto
Naoki
N
Shoji
Tetsuo
T
Inaba
Masaaki
M
Nakatani
Tatsuya
T
Nishizawa
Yoshiki
Y
D015502:Absorptiometry, Photon; D000273:Adipose Tissue / Q000378:metabolism*; D001823:Body Composition; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods; D013997:Time Factors