Two new methyl chanofruticosinates from Kopsia flavida blume.
Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1-decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N-decarbomethoxy-14,15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1-decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.
Husain
Khairana
K
Department of Pharmacy, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia. khairana@medic.ukm.my
Jantan
Ibrahim
I
Said
Ikram M
IM
Aimi
Norio
N
Takayama
Hiromitsu
H
D000470:Alkaloids / Q000737:chemistry*; D029062:Apocynaceae; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
D000470:Alkaloids; D010936:Plant Extracts