title: Face and emotion recognition deficits in Turner syndrome: a possible role for X-linked genes in amygdala development.
abstract: Face recognition is thought to rely on configural visual processing. Where face recognition impairments have been identified, qualitatively delayed or anomalous configural processing has also been found. A group of women with Turner syndrome (TS) with monosomy for a single maternal X chromosome (45, Xm) showed an impairment in face recognition skills compared with normally developing women. However, normal configural face-processing abilities were apparent. The ability to recognize facial expressions of emotion, particularly fear, was also impaired in this TS subgroup. Face recognition and fear recognition accuracy were significantly correlated in the female control group but not in women with TS. The authors therefore suggest that anomalies in amygdala function may be a neurological feature of TS of this karyotype.
authors.affiliation: Department of Behavioural and Brain Sciences, Institute of Child Health, University College London, England. kelgar@ich.ucl.ac.uk
authors.forename: Kate
authors.initials: K
authors.lastname: Lawrence
authors.forename: Jonna
authors.initials: J
authors.lastname: Kuntsi
authors.forename: Michael
authors.initials: M
authors.lastname: Coleman
authors.forename: Ruth
authors.initials: R
authors.lastname: Campbell
authors.forename: David
authors.initials: D
authors.lastname: Skuse
mesh_terms: D000293:Adolescent; D000328:Adult; D000679:Amygdala / Q000503:physiopathology*; D041321:Chromosomes, Human, X / Q000235:genetics*; D004644:Emotions / Q000502:physiology*; D005149:Facial Expression; D005239:Fear / Q000502:physiology / Q000523:psychology; D008040:Genetic Linkage / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D009006:Monosomy; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology*; D014424:Turner Syndrome / Q000235:genetics* / Q000503:physiopathology / Q000523:psychology