Management of clinical stage I nonseminomatous germ-cell testis tumors.
Nonseminomatous germ-cell tumors of the testis, the most common cancer in young adult males, are highly curable. Clinical Stage I disease represents almost a third of the patients. Three treatment strategies are currently available: surveillance, postorchiectomy chemotherapy and retroperitoneal lymph node dissection. Factors predictive of extratesticular involvement have been described, thus making it possible to tailor treatment to risk. New imaging procedures also permit staging and prediction of outcome. Decision-making is shared between the patient and his oncologist. Economic issues are better understood but should be further studied.
Flechon
Aude
A
Department of Medical Oncology, Centre Léon Bérard, Lyon, France. flechon@lyon.fnclcc.fr
Droz
Jean-Pierre
JP
D017024:Chemotherapy, Adjuvant; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000628:therapy*; D009919:Orchiectomy; D011379:Prognosis; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*