Organoruthenium(II) and (III) amidinates, (eta5-C5Me5)Ru(eta-amidinate) and (eta5-C5Me5)RuCl(eta-amidinate), as unique redox catalysts for the intramolecular Kharasch reactions: facile access to a pyrrolizidine alkaloid skeleton under mild conditions.
A novel organoruthenium(III) amidinate, (eta5-C5Me5)RuCl(eta-iPrN=C(Me)NiPr) (2), has been prepared by oxidation of organoruthenium amidinate, (eta5-C5Me5)Ru(eta-iPrN=C-(Me)NiPr) (1), by organic chlorides; both 1 and 2 are found to be good catalysts for atom-transfer cyclization of N-allyltrichloroacetamides which are useful for successful preparation of a pyrrolizidine alkaloid skeleton under mild conditions.
Nagashima
Hideo
H
Institute of Advanced Material Study, Kyushu University, Kasuga, Fukuoka 816-8580, Japan. nagasima@cm.kyushu-u.ac.jp
Gondo
Mitsuru
M
Masuda
Satoshi
S
Kondo
Hideo
H
Yamaguchi
Yoshitaka
Y
Matsubara
Kouki
K