title: Nanotechnological approaches for the delivery of macromolecules.
abstract: In this overview, novel approaches are described for the controlled release and/or for the targeted delivery of macromolecules such as proteins and DNA. The building stones of these highly complex systems are (phospho)lipids and/or (biodegradable) polymers. They should be carefully chosen and preparation protocols should be rationally designed to maximize chances for success.
authors.affiliation: Department Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, Utrecht 3508 TB, The Netherlands. d.j.a.crommelin@pharm.uu.nl
authors.forename: Daan J A
authors.initials: DJ
authors.lastname: Crommelin
authors.forename: Gert
authors.initials: G
authors.lastname: Storm
authors.forename: Wim
authors.initials: W
authors.lastname: Jiskoot
authors.forename: Robert
authors.initials: R
authors.lastname: Stenekes
authors.forename: Enrico
authors.initials: E
authors.lastname: Mastrobattista
authors.forename: Wim E
authors.initials: WE
authors.lastname: Hennink
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D046911:Macromolecular Substances; D036103:Nanotechnology / Q000379:methods*
chemical_list: D046911:Macromolecular Substances