title: The importance of opioid tolerance: a therapeutic paradox.
authors.affiliation: Palliative Care Service, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
authors.forename: A Reed
authors.initials: AR
authors.lastname: Thompson
authors.forename: James B
authors.initials: JB
authors.lastname: Ray
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance / Q000502:physiology*; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods; D012131:Respiratory Insufficiency / Q000209:etiology
chemical_list: D000701:Analgesics, Opioid