title: A titanium-catalyzed three-component coupling to generate alpha,beta-unsaturated beta-iminoamines.
abstract: The three-component coupling of an amine, alkyne, and isonitrile is facilitated by a titanium complex bearing the N,N-di(pyrrolyl-alpha-methyl)-N-methylamine (dpma) ligand. From this methodology, alpha,beta-unsaturated beta-iminoamines are generated regioselectively with many substrates and are available on multigram scales.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Changsheng
authors.initials: C
authors.lastname: Cao
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Shi
authors.forename: Aaron L
authors.initials: AL
authors.lastname: Odom