title: [Distribution of neuropeptide Y-like immunoreactive fiber in rat temporomandibular joint].
abstract: OBJECTIVE
  This investigation aimed at explore the total distribution of neuropeptide Y-like immunoreactive (NPY-LI) fibers and their changes post-trauma in rat temporomandibular joints (TMJs).
  
  
  METHODS
  Six groups of rats were killed individually before trauma, 1, 3, 7, 14 and 28 days after trauma. TMJs were extracted totally, and the avidin-biotin-peroxidase complex method and image analysis were employed to detect NPY-LI fibers in frozen sections of TMJs.
  
  
  RESULTS
  NPY-LI fibers were distributed extensively in TMJs, except the central disc band and bone, and they were mainly located around blood vessels, especially arteries. The densities of fibers in the six groups were 160.4 +/- 27.5, 95.8 +/- 16.4, 88.6 +/- 14.5, 114.3 +/- 17.0, 135.0 +/- 20.7, 158.6 +/- 19.5 (unit:mm2).
  
  
  CONCLUSIONS
  NPY-LI nerve fibers are distributed extensively in the periphery of blood vessels of TMJs and densities changed dynamically when TMJs were impacted. NPY may play an important role in pathologic change of TMJ by regulating local blood circulation.
authors.affiliation: Department of Stomatology, Eighty-first Hospital of PLA.
authors.forename: Xianghui
authors.initials: X
authors.lastname: Liu
authors.forename: Zhenglin
authors.initials: Z
authors.lastname: Xu
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.forename: Fangjie
authors.initials: F
authors.lastname: Si
authors.forename: Zhiren
authors.initials: Z
authors.lastname: Rao
mesh_terms: D000818:Animals; D008297:Male; D009412:Nerve Fibers / Q000378:metabolism / Q000473:pathology*; D009478:Neuropeptide Y / Q000032:analysis* / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012815:Signal Processing, Computer-Assisted; D013704:Temporomandibular Joint / Q000294:innervation*
chemical_list: D009478:Neuropeptide Y