[Perspectives on the oncologist pharmacopoeia].
MGI114, ET743, BBR3464, ZD0473, ZD9331, BN80915, J107088, F11782, XR11576, BMS247550, PS341, UCN01, ISIS 3521, STI571, ZD1839, IMC-C225, OSI774, SU5416, DNA minor and major grooves, chimeric proteins, ribonucleotide reductase, topoisomerases, tubuline, proteasome, protein kinase C, bcr-abl, EGF or VEGF tyrosine kinase receptors are code names (somewhat barbarian) and targets for new drugs which will complement the therapeutic arsenal of the twenty-first century oncologist. This review provides a survey their clinical advances.
Lansiaux
Amélie
A
Laboratoire de pharmacologie antitumorale du Centre Oscar-Lambret et Unité 524 Inserm, 1, place de Verdun, 59045 Lille France.
Bailly
Christian
C
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D001897:Boronic Acids / Q000627:therapeutic use; D000069286:Bortezomib; D004149:Dioxoles / Q000627:therapeutic use; D007211:Indoles / Q000627:therapeutic use; D007546:Isoquinolines / Q000627:therapeutic use; D009369:Neoplasms / Q000188:drug therapy*; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D011480:Protease Inhibitors / Q000627:therapeutic use; D011719:Pyrazines / Q000627:therapeutic use; D011758:Pyrroles / Q000627:therapeutic use; D011799:Quinazolines / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000627:therapeutic use; D044005:Tetrahydroisoquinolines; D000077606:Trabectedin
D020533:Angiogenesis Inhibitors; D000970:Antineoplastic Agents; D018906:Antineoplastic Agents, Alkylating; D001897:Boronic Acids; D004149:Dioxoles; D007211:Indoles; D007546:Isoquinolines; D009944:Organoplatinum Compounds; D011480:Protease Inhibitors; D011719:Pyrazines; D011758:Pyrroles; D011799:Quinazolines; D012717:Sesquiterpenes; D044005:Tetrahydroisoquinolines; C094299:ZD 9331; C110525:amminedichloro(2-methylpyridine)platinum(II); D000069286:Bortezomib; C102714:irofulven; C116890:Semaxinib; C114062:BBR 3464; D000077606:Trabectedin