The Kin I kinesins are microtubule end-stimulated ATPases.
The Kin I kinesins are microtubule-destabilizing enzymes important for neuronal transport, spindle assembly, and chromosome segregation. now show that the Kin I MCAK is a microtubule end-stimulated ATPase that can catalytically depolymerize MT's.
Walczak
Claire E
CE
Medical Sciences, Indiana University, 915 E. 3rd Street, Myers Hall 262, Bloomington, IN 47405, USA.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D016547:Kinesins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological
C091489:KIF2C protein, human; D000251:Adenosine Triphosphatases; D016547:Kinesins