Metastatic potential of dermatofibrosarcoma protuberans with fibrosarcomatous change.
Dermatofibrosarcoma protuberans (DFSP) is a relatively uncommon fibrohistiocytic tumor that is locally aggressive. DFSP is associated with frequent local recurrences but rarely metastasizes. It has been suggested that fibrosarcomatous change within a dermatofibrosarcoma protuberans (DFSP-FS) is associated with increased risk of local recurrence and distant metastases. Metastases remain rare, however, and are typically preceded by multiple local recurrences. We report a rare case of a DFSP-FS metastasis to the head of the pancreas without any preceding local recurrence.
Minter
Rebecca M
RM
Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA.
Reith
John D
JD
Hochwald
Steven N
SN
D000328:Adult; D018223:Dermatofibrosarcoma / Q000556:secondary*; D005260:Female; D005354:Fibrosarcoma / Q000556:secondary*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010190:Pancreatic Neoplasms / Q000556:secondary*; D012307:Risk Factors; D012878:Skin Neoplasms / Q000473:pathology*