Enantioselective synthesis of slagenins A-C.
[formula: see text] An enantioselective synthesis of slagenins A-C (1a-c) is described in which their absolute stereochemistries were established. The key step in the synthesis involved the efficient condensation of 2-methoxy-dihydro-furan-3-one 9 and urea to construct the slagenin bicycle core.
Jiang
Biao
B
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, Peoples Republic of China. jiangb@pub.sioc.ac.cn
Liu
Jia-Feng
JF
Zhao
Sheng-Yin
SY