title: [Lupus hepatitis].
abstract: We report the case of 42 year-old man who presents an acute polyarthritis associated with systemic manifestation and immunologic disorders related to systemic lupus erythematosus. Hepatic tests show cholostase and cytolysis. Hepatic involvement is linked with systemic lupus erythematosus after exclusion of hepatotoxic drugs, viral hepatitis and absence of anti mitochondrial and anti muscle antibodies. Lupus hepatitis seems to be correlated with autoantibodies to ribosomal P protein. Its treatment remains to be defined.
authors.affiliation: Service de Rhumatologie, Hôpital Charles Nicolle.
authors.forename: Yahia Chiraz
authors.initials: YC
authors.lastname: Ben Hadj
authors.forename: Lilia
authors.initials: L
authors.lastname: Chaabouni
authors.forename: Kchir Mohamed
authors.initials: KM
authors.lastname: Montacer
authors.forename: Feriel
authors.initials: F
authors.lastname: Abid
authors.forename: Rafik
authors.initials: R
authors.lastname: Zouari
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000276:immunology; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D015800:Protozoan Proteins; D012269:Ribosomal Proteins / Q000276:immunology
chemical_list: D001323:Autoantibodies; C064601:L12E protein, Trypanosoma cruzi; D015800:Protozoan Proteins; D012269:Ribosomal Proteins