title: Parahippocampal gray matter density in panic disorder: a voxel-based morphometric study.
abstract: OBJECTIVE
  The authors examined possible cerebral gray matter abnormalities in patients with panic disorder.
  
  
  METHODS
  Gray matter concentration in 18 panic disorder outpatients and 18 healthy subjects was compared by using a voxel-based morphometry approach.
  
  
  RESULTS
  Gray matter density of the left parahippocampal gyrus was significantly lower in patients with panic disorder compared with healthy subjects.
  
  
  CONCLUSIONS
  This result provides further support for the involvement of the parahippocampal area in the pathophysiology of panic disorder.
authors.affiliation: Institut Clínic de Psiquiatria i Psicologia, Corporació Sanitària Clínic, I.D.I.B.A.S., Barcelona, Catalonia, Spain. trocosmos@yahoo.es
authors.forename: Guillem
authors.initials: G
authors.lastname: Massana
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Serra-Grabulosa
authors.forename: Pilar
authors.initials: P
authors.lastname: Salgado-Pineda
authors.forename: Cristòbal
authors.initials: C
authors.lastname: Gastó
authors.forename: Carme
authors.initials: C
authors.lastname: Junqué
authors.forename: Joan
authors.initials: J
authors.lastname: Massana
authors.forename: José María
authors.initials: JM
authors.lastname: Mercader
mesh_terms: D000328:Adult; D000379:Agoraphobia / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D016584:Panic Disorder / Q000175:diagnosis* / Q000503:physiopathology; D020534:Parahippocampal Gyrus / Q000033:anatomy & histology* / Q000503:physiopathology