title: [Study on effects of scutellarin on scavenging reactive oxygen].
abstract: OBJECTIVE
  To study the antioxidative effects and its mechanism of scutellarin.
  
  
  METHODS
  Scavenging effects of scutellarin on hydroxyl radical (OH.) produced from 0-phenathroline-ascorbic acid system, super oxide anion radical (O2-.) produced from xanthine-xanthine oxidase-luminol system and hydrogen peroxide was studied by a chemiluminescence assay.
  
  
  RESULTS
  Scutellarin has a significant effect on scavenging hydroxyl radicals, super oxide anion radicals, hydrogen peroxide, their IC50 are 66 micrograms/ml, 1.3 micrograms/ml and 1.6 micrograms/ml respectively.
  
  
  CONCLUSIONS
  Scutellarin is an efficiency antioxidant.
authors.affiliation: Institute of Pharmacy, Huazhong University of Science & Technology, Wuhan 430074.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.forename: Xiangliang
authors.initials: X
authors.lastname: Yang
authors.forename: Linzhu
authors.initials: L
authors.lastname: Zhou
authors.forename: Huibi
authors.initials: H
authors.lastname: Xu
mesh_terms: D047310:Apigenin; D019659:Asteraceae / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000737:chemistry*; D005965:Glucuronates; D006861:Hydrogen Peroxide / Q000032:analysis; D017665:Hydroxyl Radical / Q000032:analysis; D008163:Luminescent Measurements; D010946:Plants, Medicinal / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000032:analysis*; D013481:Superoxides / Q000032:analysis
chemical_list: D005419:Flavonoids; D016166:Free Radical Scavengers; D005965:Glucuronates; D017382:Reactive Oxygen Species; D013481:Superoxides; C484876:scutellarin; D017665:Hydroxyl Radical; D047310:Apigenin; D006861:Hydrogen Peroxide; C458179:scutellarein