title: Alveolar ridge augmentation using titanium micromesh: an experimental study in dogs.
abstract: OBJECTIVE
  Augmentation of the alveolar ridge before implant placement is frequently performed. The purpose of this study was to compare the amount and quality of bone formation under Micro Titanium Augmentation Mesh (M-TAM) when used alone for guided tissue regeneration or in combination with a porous hydroxyapatite (HA) bone graft substitute.
  
  
  METHODS
  Nine adult female dogs underwent extraction of premolars and molars and had a knife-edge ridge created. Three months later, the ridges were augmented with either M-TAM alone or M-TAM with a nonresorbable porous HA (Interpore 200; Interpore Cross International, Irvine, CA). Six months after augmentation, the dogs were killed, and the mandibles were harvested and imaged using 3-dimensional computed axial tomography. Statistical analysis was performed from the data obtained from the scans. The mandibles were then fixed, sectioned, and examined by light microscopy.
  
  
  RESULTS
  Dehiscence occurred in 22 of 32 experimental sites. Seven of these 22 dehisced sites showed increased ridge width. Ridge width increased in both the HA and non-HA groups. The HA group showed a greater increase in ridge width.
  
  
  CONCLUSIONS
  A high rate of dehiscence was observed in this animal study using M-TAM for guided tissue regeneration. In animals that did not dehisce, increased width was greater when nonresorbable porous HA was used as a bone graft substitute.
authors.affiliation: Division of Oral and Maxillofacial Surgery, Columbia University School of Dental and Oral Surgery and Dental Service, New York-Presbyterian Hospital, New York, NY, USA. sbe2002@columbia.edu
authors.forename: Sidney B
authors.initials: SB
authors.lastname: Eisig
authors.forename: Victor
authors.initials: V
authors.lastname: Ho
authors.forename: Richard
authors.initials: R
authors.lastname: Kraut
authors.forename: Peggy
authors.initials: P
authors.lastname: Lalor
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000295:instrumentation / Q000379:methods*; D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D004285:Dogs; D017886:Durapatite; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000009:adverse effects; D007568:Jaw / Q000000981:diagnostic imaging; D013526:Surgical Mesh; D013529:Surgical Wound Dehiscence; D014025:Titanium; D036542:Tomography, Spiral Computed
chemical_list: D018786:Bone Substitutes; D017886:Durapatite; D014025:Titanium