title: Severe spontaneous intracranial haematoma in a HIV-negative 66-year-old mild haemophiliac. Complete recovery with the use of 1-month factor VIII replacement.
abstract: Intracranial haemorrhage is the most feared manifestation of haemophilia and is usually seen in severe forms. We report herein the case of a 66-year-old HIV-negative patient with mild haemophilia (factor VIII: 7%) who presented with a spontaneous and massive intracranial haematoma causing hemiplegia and aphasia. We discuss the management of this peculiar situation emphasizing the need for rapid and adapted FVIII replacement. A complete recovery was obtained using this strategy combined with initial resuscitation measures and subsequent physical therapy.
authors.affiliation: Department of Haematology, Centre Hospitalier de la Côte Basque, Bayonne, France. fbauder001@chcb.rss.fr
authors.forename: F
authors.initials: F
authors.lastname: Bauduer
authors.forename: P
authors.initials: P
authors.lastname: Delpy
authors.forename: C
authors.initials: C
authors.lastname: Borde
authors.forename: L
authors.initials: L
authors.lastname: Ducout
authors.forename: J B
authors.initials: JB
authors.lastname: Boutin
mesh_terms: D000368:Aged; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D005169:Factor VIII / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D005169:Factor VIII