[Calcium needs in hemodialyzed-parathyroidectomized patients].
Parathyroidectomy changes the homeostasis of calcium balance in patients under dialysis for kidney failure. The aim of this work is to value calcium needs in 20 hemodialysed patients who underwent parathyroidectomy, in the department of nephrology of UHC Ibn Rochd of Casablanca from January 1994 to June 1999. These patients, 12 women (60%) and 8 men (40%), aged between 14 and 70 years (mean=46.10+/-13.62 years). Hungry bone syndrome was noted in 8 patients and postoperative hypocalcemia in 15 (75%). Mean minimal serum calcium was 196+/-0.21 mmol/l, with clinical signs in 6 patients. Mean calcium supplement the first postoperative week was 18.1+/-0,54 g/day in the 8 patients with hungry bone syndrome and 14.28+/-0,86 g/day in the 12 remaining patients. Between 6 and 18 months postoperatively, required calcium supplementation was 4.5 to 12 g/day in patients with hungry bone syndrome compared with 3 to 6g/day at the remaining patients. Mean serum calcium remained stable between 2.16 mmol/l to the 3(rd) month and 2.48 mmol/l to the 36(th) month. Postoperative hypocalcemia remains a major concern after parathyroidectomy requiring massive substitution with calcium and active vitamin D metabolite under close supervision to spare these patients from hypercalcemia resulting from parathyroid dysfunction.
Zahiri
Khalid
K
Service de Néphrologie et d'Hémodialyse, CHU Ibn Rochd, Casablanca, Maroc. khlaid_zahiri@yahoo.fr
Hachim
Khadija
K
Fatihi
El Mustapha
el M
Benghanem
Mohamed Gharbi
MG
Ramdani
Benyounès
B
Zaïd
Driss
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002119:Calcium Carbonate / Q000627:therapeutic use*; D002762:Cholecalciferol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000601:surgery; D006996:Hypocalcemia / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016105:Parathyroidectomy / Q000009:adverse effects*; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000628:therapy; D012189:Retrospective Studies; D016896:Treatment Outcome
D002762:Cholecalciferol; D002119:Calcium Carbonate