title: Mirtazapine for pruritus.
abstract: Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies. Medical management recently has included the use of ondansetron and paroxetine. We report four patients whose pruritus responded to mirtazapine.
authors.affiliation: The Harry R. Horvitz Center for Palliative Medicine, Cleveland, OH, USA.
authors.forename: Mellar P
authors.initials: MP
authors.lastname: Davis
authors.forename: Jan L
authors.initials: JL
authors.lastname: Frandsen
authors.forename: Declan
authors.initials: D
authors.lastname: Walsh
authors.forename: Steven
authors.initials: S
authors.lastname: Andresen
authors.forename: Sandy
authors.initials: S
authors.lastname: Taylor
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D002779:Cholestasis / Q000150:complications; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D008875:Middle Aged; D000078785:Mirtazapine; D009369:Neoplasms / Q000150:complications; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D051437:Renal Insufficiency / Q000150:complications
chemical_list: D000929:Antidepressive Agents, Tricyclic; D006634:Histamine H1 Antagonists; D008803:Mianserin; D000078785:Mirtazapine