title: Deep brain stimulation: a new treatment for Parkinson's disease.
abstract: Patients suffering from advanced Parkinson's disease (PD) often experience an array of symptoms that greatly affect their quality of life. Deep brain stimulation (DBS) of the bilateral subthalamic nuclei (STN) has produced remarkable improvements in people with advanced PD whose symptoms are not adequately controlled with medication. We present a case report on a patient who has benefitted immensely from bilateral STN stimulation. Levodopa responsiveness, disabling motor fluctuations and dyskinesias, cognition, and concurrent illness are major factors in identifying candidates who will receive the greatest benefit.
authors.affiliation: Division of Movement Disorders, Department of Neurology, Vanderbilt University Medical Center, Medical Center South, 2100 Pierce Ave., Nashville, TN 37212, USA.
authors.forename: Myrandele
authors.initials: M
authors.lastname: Damian
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Davis
authors.forename: Peter E
authors.initials: PE
authors.lastname: Konrad
authors.forename: Amanda G
authors.initials: AG
authors.lastname: Roberts
authors.forename: Alyssa A
authors.initials: AA
authors.lastname: Pfister
authors.forename: P David
authors.initials: PD
authors.lastname: Charles
mesh_terms: D000328:Adult; D004599:Electric Stimulation Therapy; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000502:physiology*