title: Chiral ligand-controlled asymmetric conjugate addition of lithium amides to enoates.
abstract: The external chiral ligand-controlled asymmetric conjugate addition reaction of lithium amides with alpha,beta-unsaturated esters provided beta-amino esters in high yields and high enantioselectivities.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Doi
authors.forename: Takeo
authors.initials: T
authors.lastname: Sakai
authors.forename: Mayu
authors.initials: M
authors.lastname: Iguchi
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Yamada
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tomioka
mesh_terms: D000577:Amides / Q000737:chemistry*; D000596:Amino Acids / Q000138:chemical synthesis*; D004952:Esters / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D000577:Amides; D000596:Amino Acids; D004952:Esters; D009942:Organometallic Compounds; D008094:Lithium