title: [Selection for disease and epidemic resistance in domestic ruminants and swine by indicator traits, marker and causal genes--a review. Part 2: Special immunogenetics of sheep and goats with particular regard for endoparasitoses, scrapie, foot rot and maedi-visna virus infection].
abstract: The introduction of the first part deals with immunogenetic investigations on the field of life-stock. The main chapter is outlined as a tabular overview of current opportunities of the application of indicator traits as well as marker and causal genes in breeding for disease resistance in cattle, sheep, goats and swine. In the discussion of the second part, emphasis was laied on diseases of small ruminants in central and western Europe with special respect of endoparasitoses, scrapie, foot-rot and maedi-visna virus infection. Indicator traits are discussed with respect of their advantages and disadvantages. The rigorous selection on specific traits is connected with an increase of the number of homozygotes. In contrary, pathogens do undergo mutations, thus escaping the host's immune system. Out of this point of view it is advisable, to set on selection very cautiously. The role of technologies of modern immunogenetics is pointed out in respect of constructing disease resistant animals.
authors.affiliation: II. Medizinischen Universitätsklinik für Klauentiere der Veterinärmedizinischen Universität Wien. wimmers@itz.uni-bonn.de
authors.forename: W
authors.initials: W
authors.lastname: Sipos
authors.forename: F
authors.initials: F
authors.lastname: Schmoll
authors.forename: K
authors.initials: K
authors.lastname: Wimmers
mesh_terms: D000818:Animals; D001947:Breeding; D004198:Disease Susceptibility / Q000662:veterinary; D005260:Female; D005535:Foot Rot / Q000235:genetics / Q000276:immunology; D005819:Genetic Markers; D015511:Goat Diseases / Q000235:genetics / Q000276:immunology*; D006041:Goats; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics*; D008297:Male; D010273:Parasitic Diseases, Animal / Q000235:genetics / Q000276:immunology; D012608:Scrapie / Q000235:genetics / Q000276:immunology; D012641:Selection, Genetic; D012756:Sheep; D012757:Sheep Diseases / Q000235:genetics / Q000276:immunology*; D016182:Visna / Q000235:genetics / Q000276:immunology
chemical_list: D005819:Genetic Markers