title: Ovary specific immune response during Plasmodium yoelii yoelii infection in malaria vector Anopheles stephensi (Diptera:Insecta).
abstract: Innate immune related polypeptides expression during three gonotrophic cycles in the ovaries of major disease vector mosquito A. stephensi has been analyzed following infection by malaria parasite, P. yoelii yoelii. Seventeen polypeptides were induced in the ovaries of various stages due to parasitic infection. Most of proteins were induced systemically during early stages of infection suggesting the possibility of immune related signalling process. The reduction in the quantity of protein contents in infected mosquitoes has been ascribed to the repression of seven polypeptides and in turn correlated with the fecundity reduction. The mechanism of these responses and their significance for malaria transmission and fecundity reduction are discussed.
authors.affiliation: Department of Biosciences, Maharshi Dayanand University, Rohtak 124 001, India. gakharsk@yahoo.co.in
authors.forename: S K
authors.initials: SK
authors.lastname: Gakhar
authors.forename: Harish
authors.initials: H
authors.lastname: Shandilya
mesh_terms: D000818:Animals; D000852:Anopheles / Q000276:immunology* / Q000469:parasitology; D005260:Female; D007303:Insect Vectors; D008288:Malaria / Q000635:transmission*; D010053:Ovary / Q000276:immunology*; D010967:Plasmodium yoelii / Q000302:isolation & purification*