Multiple myeloma associated with lactic acidosis.
Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-kappa) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.
Ustun
Celalettin
C
Department of Internal Medicine, Medical College of Georgia, Veterans Affairs Medical Center, 1 Freedom Way, Augusta, GA 30904, USA.
Fall
Pamela
P
Szerlip
Harold M
HM
Jillella
Anand
A
Hendricks
Linda
L
Burgess
Russell
R
Dainer
Paul
P
D000140:Acidosis, Lactic / Q000175:diagnosis / Q000209:etiology*; D018450:Disease Progression; D006801:Humans; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D019344:Lactic Acid / Q000097:blood; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012008:Recurrence
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D019344:Lactic Acid