False-positive reaction to VDRL test with prozone phenomena. Association with lymphosarcoma.
A patient with lymphosarcoma had a VDRL test reactive at 1:256. A prozone phenomenon was also present. The nontreponemal test result was shown to be a false-positive reaction by nonreactive Treponema pallidum immobilization and fluorescent treponemal antibody absorption tests. High-titer serologic tests for syphilis are uncommon, and prozone reactions are previously unrecorded in the false-positive reactor.
Wuepper
K D
KD
Venereal Disease Branch, Communicable Disease Center, Public Health Service, Department of Public Health, San Francisco, USA.
Tuffanelli
D L
DL
D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000276:immunology*; D008875:Middle Aged; D013587:Syphilis / Q000175:diagnosis*; D013588:Syphilis Serodiagnosis