title: Atrial fibrillation during adjuvant chemotherapy with docetaxel: a case report.
abstract: A 46-year-old woman had an episode of atrial fibrillation during infusion of docetaxel as adjuvant chemotherapy for an infiltrating ductal carcinoma of the breast. All cardiological tests performed before treatment were normal and there was no evidence of thyroid dysfunction nor any objective or anamnestic data indicating acute or chronic cardiovascular disease. None of the drugs administered has ever shown any proarrhythmic activity. In controlled clinical trials docetaxel was found to have a very low cardiotoxicity.
authors.affiliation: Medical Oncology, Department of Experimental Medicine and Pathology, University of Rome La Sapienza, Rome, Italy.
authors.forename: Marzia
authors.initials: M
authors.lastname: Palma
authors.forename: Andrea
authors.initials: A
authors.lastname: Mancuso
authors.forename: Federico
authors.initials: F
authors.lastname: Grifalchi
authors.forename: Antonio
authors.initials: A
authors.lastname: Lugini
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Pizzardi
authors.forename: Enrico
authors.initials: E
authors.lastname: Cortesi
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001281:Atrial Fibrillation / Q000139:chemically induced*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy / Q000601:surgery; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D003520:Cyclophosphamide / Q000008:administration & dosage; D000077143:Docetaxel; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D043823:Taxoids; D016896:Treatment Outcome
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D015251:Epirubicin; D003520:Cyclophosphamide; D017239:Paclitaxel; D005472:Fluorouracil