[A case of advanced colon cancer responding to treatment with levofolinate combined with 5-fluorouracil].
The patient was a 70-year-old man who had sigmoid colon cancer with multiple lung and paraaortic lymph node metastases. Sigmoidectomy was performed on August 3, 2001. After the operation, combined l-Leucovorin (LV) + 5-fluorouracil (5-FU) was carried out. As a result, lung and lymph node metastases were reduced markedly and CEA level decreased. It is suggested that this combination therapy may be useful for advanced colon cancer patients.
Sawada
Mitsuhiro
M
Dept. of Surgery, Hirosaki Central Hospital.
Ono
Yuichi
Y
Fukushima
Matsuro
M
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D014057:Tomography, X-Ray Computed
D002955:Leucovorin; D005472:Fluorouracil