title: Design and development of a common synthetic strategy for a variety of 1-N-iminosugars.
abstract: [formula: see text] A new synthetic strategy has been developed for a general approach toward the synthesis of a variety of 1-N-iminosugar-type glycosidase inhibitors utilizing precursors developed by the PET-mediated cyclization of alpha-trimethylsilylmethylamine radical cation to a tethered pi-functionality.
authors.affiliation: Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune 411008, India. pandey@ems.ncl.res.in
authors.forename: Ganesh
authors.initials: G
authors.lastname: Pandey
authors.forename: Manmohan
authors.initials: M
authors.lastname: Kapur
mesh_terms: D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D006027:Glycosides / Q000138:chemical synthesis* / Q000494:pharmacology; D007097:Imines / Q000138:chemical synthesis; D050112:Imino Pyranoses; D010880:Piperidines / Q000138:chemical synthesis
chemical_list: D006027:Glycosides; D007097:Imines; D050112:Imino Pyranoses; D010880:Piperidines; C098432:isofagomine; D006026:Glycoside Hydrolases