title: Cataract formation after initial trabeculectomy in young patients.
abstract: OBJECTIVE
  To evaluate the risk of cataract formation in young patients after initial trabeculectomy.
  
  
  METHODS
  Retrospective, noncomparative case series.
  
  
  METHODS
  Thirty-four eyes from 27 patients undergoing initial trabeculectomy at the Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary (mean age, 43.7 years; range, 12-54 years).
  
  
  METHODS
  Follow-up averaged 42.6 months (range, 11-90 months).
  
  
  METHODS
  Lens status was observed before surgery and at 3 months; 6 months; and 1, 2, 3, 4, 5, and 6 years after initial trabeculectomy.
  
  
  METHODS
  The main outcome measure was defined as cataract extraction for visually significant lenticular opacifications that developed after trabeculectomy.
  
  
  RESULTS
  The rate of cataract extraction after initial trabeculectomy was 24% (n = 8). The average time from trabeculectomy to cataract extraction was 26 months (range, 5-58 months). Progression of lenticular opacities occurred throughout the follow-up period. There was no increased rate of cataract formation in subjects with uveitic and steroid-induced glaucoma when compared with all other types of glaucoma. In the patients with both eyes in the study, the first eye was a predictor of cataract progression in the fellow eye.
  
  
  CONCLUSIONS
  Cataract is a common complication after trabeculectomy in young patients. The 24% rate of cataract extraction after trabeculectomy reported in this study is a significant risk of which young patients contemplating surgery should be aware.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.
authors.forename: Ron Afshari
authors.initials: RA
authors.lastname: Adelman
authors.forename: Stacey C
authors.initials: SC
authors.lastname: Brauner
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Afshari
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Grosskreutz
mesh_terms: D000293:Adolescent; D000328:Adult; D002386:Cataract / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D002387:Cataract Extraction / Q000706:statistics & numerical data; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014130:Trabeculectomy / Q000009:adverse effects*