[Effects of invigorating the kidney and strengthening the bones capsule on osteoporosis in ovariectomized rats].
OBJECTIVE
To study the therapeutic effects of inrigorating the kidney and strengthening the bones capsule(IKSBC) on osteoporotic ovariectomized(OVX) rat model.


METHODS
The concentrations of calcium, phosphorus and ALP in serum of ovariectomized rats were determined by clinical biochemical assay, and the right hind leg thighbones of ovariectomized rats were reserved for the preparation of bone specimens and were studied by bone histomorphometry.


RESULTS
After treatment with IKSBC, the concentrations of calcium and phosphorus in ovariectomized rat serum were increased, the activity of ALP was decreased and the percentage of relative trabecular volume was increased significantly as compared with that before treatment(P < 0.05).


CONCLUSIONS
IKSBC possesses some therapeutic effects on osteoporotic rat model.
Li
Shenggang
S
Qingdao Institution for Drug Control, Qingdao 266071.
Yang
Xiaofeng
X
Yu
Dezhi
D
Zhu
Aimin
A
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D002118:Calcium / Q000097:blood; D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005269:Femur / Q000473:pathology; D010024:Osteoporosis / Q000097:blood* / Q000473:pathology; D010052:Ovariectomy; D010758:Phosphorus / Q000097:blood; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D002214:Capsules; D004365:Drugs, Chinese Herbal; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium