title: [Pulmonary veno-occlusive disease in a patient with HIV infection. A case report with autopsy findings].
abstract: We relate the autopsy findings of a case of pulmonary veno-occlusive disease which occurred in an HIV-infected intravenous drug abuser. This exceedingly rare disease, of unknown cause, is responsible for 10% of primary pulmonary hypertension. Histologically, the disease is characterized by a fibrous intimal thickening of small and medium sized pulmonary veins associated with congestive and dilated capillary network and alveolar haemorrhage. The occurrence of primary pulmonary hypertension in HIV positive patients is 25 times more frequent than in the general population. This is the third reported case of pulmonary veno-occlusive disease occurring in a HIV positive patient. It suggests the role of HIV in the pathogenesis of these vascular lesions.
authors.affiliation: Service d'Anatomie et de Cytologie Pathologiques, Hôpital Avicenne, Bobigny. imagerie.anapath@ap-hop-paris.fr
authors.forename: Muriel
authors.initials: M
authors.lastname: Hourseau
authors.forename: Frédérique
authors.initials: F
authors.lastname: Capron
authors.forename: Hilario
authors.initials: H
authors.lastname: Nunes
authors.forename: Pascal
authors.initials: P
authors.lastname: Godmer
authors.forename: Antoine
authors.initials: A
authors.lastname: Martin
authors.forename: Marianne
authors.initials: M
authors.lastname: Kambouchner
mesh_terms: D000328:Adult; D001344:Autopsy; D017809:Fatal Outcome; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D011667:Pulmonary Veins / Q000473:pathology; D011668:Pulmonary Veno-Occlusive Disease / Q000209:etiology* / Q000473:pathology*