[Progresses on macrophages of male reproductive tract].
The review summarized the recent progress on macrophages of male reproductive tract and the action of macrophages on male reproductive physiology and pathology. The close correlation and effect between testicular macrophages and Leydig cells, Sertoli cells, germ cells, hypothalamic-pituitary-gonadal axis were introduced, respectively. At the same time, it pointed out the changes of macrophages' morphology and function in immune orchitis, and their regulation on the development of orchitis. So the complex immune regulation network in testes and testicular macrophages playing an important role on spermatogenesis and the stableness of spermatogenetic microenvironment in testes were further illuminated, which can provide theoretical basis for clinic therapy.
Li
Jing-Jing
JJ
Department of Histology and Embryology, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Wang
Tao
T
Wang
Geng-Xin
GX
D005837:Genitalia, Male / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D006801:Humans; D008264:Macrophages / Q000166:cytology / Q000276:immunology*; D008297:Male; D009920:Orchitis / Q000276:immunology / Q000473:pathology; D013091:Spermatogenesis / Q000502:physiology