title: Disseminated Acanthamoeba infection in a human immunodeficiency virus-infected infant.
abstract: Infection with Acanthamoeba is difficult to diagnose and treat. We present the first case of disseminated Acanthamoeba infection in an HIV-infected infant. The infant survived 2 years with treatment with several agents having anti-Acanthamoeba activity in vitro.
authors.affiliation: Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, 77030, USA. hlschwar@texaschildrenshospital.org
authors.forename: Heidi
authors.initials: H
authors.lastname: Schwarzwald
authors.forename: Purvi
authors.initials: P
authors.lastname: Shah
authors.forename: John
authors.initials: J
authors.lastname: Hicks
authors.forename: Moise
authors.initials: M
authors.lastname: Levy
authors.forename: Milton L
authors.initials: ML
authors.lastname: Wagner
authors.forename: Mark W
authors.initials: MW
authors.lastname: Kline
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy*; D000048:Acanthamoeba / Q000302:isolation & purification*; D000562:Amebiasis / Q000175:diagnosis* / Q000188:drug therapy*; D000563:Amebicides / Q000008:administration & dosage*; D000818:Animals; D000900:Anti-Bacterial Agents; D001707:Biopsy, Needle; D018450:Disease Progression; D004359:Drug Therapy, Combination / Q000008:administration & dosage*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D012720:Severity of Illness Index
chemical_list: D000563:Amebicides; D000900:Anti-Bacterial Agents