Changing trends in bacteriology of burns in the burns unit, Delhi, India.
A retrospective study of bacterial isolates from the wounds of patients admitted to burns unit, was undertaken at Guru Tegh Bahadur Hospital, University College of Medical Sciences, Delhi, India, over a period of 5 years between July 1997 and April 2002. The study compared the results obtained with the previous 5 years data (June 1993-June 1997) from the same unit to determine the changing patterns and emerging trends of bacterial isolates and their antimicrobial susceptibilities. Pseudomonas species (31%) and Staphylococcus aureus (22%) were the most common pathogens followed by Klebsiella species (19%). Multi-drug resistant (MDR) Acinetobacter species (9%) have emerged as an important nosocomial pathogen in our burn unit. Most of the gram-negative isolates obtained were found to be multi-drug resistant and 61% of the tested isolates were extended spectrum beta-lactamase (ESBL) producers. Concomitant resistance to penicillin and aminoglycosides was observed in 61% of Enterococcus fecalis isolates. When compared with the results of previous 5 years (June 1993-June 1997) Pseudomonas spp. was still the commonest pathogen in the burns unit. However, isolation of this organism and other gram-negative organisms has decreased in comparison to previous years. The incidence of antimicrobial resistance has markedly increased over the past years resulting in limitation of therapeutic options.
Singh
N P
NP
Department of Microbiology, Guru Tegh Bahadur Hospital, University College of Medical Sciences, New Delhi-110095, India.
Goyal
R
R
Manchanda
V
V
Das
S
S
Kaur
I
I
Talwar
V
V
D002053:Burn Units / Q000639:trends; D002056:Burns / Q000382:microbiology*; D003428:Cross Infection / Q000382:microbiology; D004351:Drug Resistance; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007194:India; D008826:Microbial Sensitivity Tests / Q000379:methods; D010403:Penicillin Resistance; D012189:Retrospective Studies; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology*