title: Two signal models of lymphocyte activation incorporate a mechanism of peripheral tolerance, and have implications for achieving immunological unresponsiveness and effective transplantation.
authors.affiliation: Department of Microbiology and Immunology, University of Saskatchewan, Saskatchewan, Canada. bretschr@duke.usask.ca
authors.forename: Peter
authors.initials: P
authors.lastname: Bretscher
authors.forename: Nathan
authors.initials: N
authors.lastname: Peters
mesh_terms: D006801:Humans; D007108:Immune Tolerance; D008213:Lymphocyte Activation / Q000276:immunology*; D017634:Self Tolerance; D015398:Signal Transduction / Q000276:immunology; D023001:Transplantation Tolerance