title: [Tryptase and fatal anaphylaxic reaction].
abstract: OBJECTIVE
  To investigate the relationship between tryptase in serum and anaphylaxis.
  
  
  METHODS
  The concentrations of tryptase in the sera of heart blood in three persons died from anaphylaxis shock were detected by ELISA. The first sample was obtained from a man, aged 38, died of injecting Amikacin. The second sample was obtained from a man, aged 42, died of injecting Cephradine. The third sample was from a woman, aged 39, died of injecting Lincomycin. All samples were stored in -20 degrees C.
  
  
  RESULTS
  The concentrations of tryptase in sera were 52 ng/ml, 121 ng/ml and 0.73 ng/ml. It was unknown why the concentration of tryptase in the third sample was normal.
  
  
  CONCLUSIONS
  In fetal anaphylaxia reaction tryptase measurement is a useful indicator, but the diagnosis is not to be based on the test alone.
authors.affiliation: Department of Forensic Medicine, Shanghai Medical School, Fudan University, Shanghai 200032. shenyiwen88@citiz.net
authors.forename: Yi-wen
authors.initials: YW
authors.lastname: Shen
authors.forename: Chao
authors.initials: C
authors.lastname: Lu
authors.forename: Zi-qin
authors.initials: ZQ
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000201:enzymology*; D015415:Biomarkers / Q000097:blood; D002423:Cause of Death; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000201:enzymology; D011180:Postmortem Changes; D012189:Retrospective Studies; D012697:Serine Endopeptidases / Q000097:blood*; D053802:Tryptases
chemical_list: D015415:Biomarkers; D012697:Serine Endopeptidases; D053802:Tryptases