title: [A histological study on healing process of palatal wound with denuded bone restored with transplanted buccal or palatal mucosa].
abstract: OBJECTIVE
  The purpose of this study was to observe the healing process of palate wound with denuded bone restored with transplanted buccal or palatal mucosa and to elucidate the mechanism of maxillary growth inhibition following palate repair.
  
  
  METHODS
  32 Japan white rabbits, 5 weeks old, were selected as the subjects for this study. They were divided into 4 groups at random. The rabbits in group I was the control without receiving any treatment. The rabbits in group II, III, IV was surgically denuded the bone of palate, and afterwards, the rabbits in group II were not received further restoration, but rabbits in group III and IV were restored with transplanted buccal and palatal mucosa respectively. From 2 to 14 weeks after surgery, at regular intervals, palatal wounds were observed by using a light microscope. Histological changes were also compared among different groups.
  
  
  RESULTS
  It was found in group II that dense connective tissue was formed 2 weeks after the surgery, and Sharpey's fibers was formed between the scar and bone tissue 4 weeks after the surgery. However, no Sharpey's fiber was found in group III and group IV, and in the latter two groups, the histological character of tissue was similar to that of the control.
  
  
  CONCLUSIONS
  Prevention of the attachment of Sharpey's fibers to the palatal bone could be effectively accomplished by covering the denuded palatal bone with the transplanted buccal or palatal mucosa.
authors.affiliation: Nanjing Stomatologic Hospital, Nanjing.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Wang
authors.forename: Bing
authors.initials: B
authors.lastname: Shi
authors.forename: Dawei
authors.initials: D
authors.lastname: Lu
authors.forename: Qinggao
authors.initials: Q
authors.lastname: Song
mesh_terms: D000818:Animals; D002972:Cleft Palate / Q000473:pathology* / Q000601:surgery*; D005260:Female; D009061:Mouth Mucosa / Q000637:transplantation*; D021362:Palate, Hard / Q000473:pathology / Q000601:surgery; D011817:Rabbits; D011897:Random Allocation; D013524:Surgical Flaps; D014945:Wound Healing