[Anaphylactic shock and myocytic necrosis after treatment with Artotec].
Treatment with non-steroid anti-inflammatory drugs associated with a prostaglandin analogue is common, but the potential cardiovascular effects are largely unknown. The authors report a case of myocardial necrosis and anaphylactic shock due to treatment with diclofenac and misoprostol. The reintroduction of the treatment in hospital led to the recurrence of the initial cutaneous and cardiac symptoms in this patient.
Meuleman
C
C
Service de cardiologie, centre hospitalier René-Dubos, 6, avenue de l'Ile-de-France, 95301 Pontoise.
Jourdain
P
P
Bellorini
M
M
Guillard
N
N
Loiret
J
J
Thebault
B
B
Sadeg
N
N
Funck
F
F
D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced*; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D004008:Diclofenac / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016595:Misoprostol / Q000009:adverse effects*; D009206:Myocardium / Q000473:pathology*; D009336:Necrosis
D000897:Anti-Ulcer Agents; D016595:Misoprostol; D004008:Diclofenac