title: An urban outbreak of leptospirosis in Mumbai, India.
abstract: An outbreak of leptospirosis occurred during the rainy season in the city of Mumbai, India. Out of 169 suspected cases, 74 (43.7%) were determined serologically positive by microagglutination test (MAT) carried out with a battery of eight pathogenic serovars, while 78 (46.1%) were shown positive for IgM antibodies to leptospira by enzyme-linked immunosorbent assay. On the basis of MAT, serovar Copenhageni accounted for 66 (89.1%) out of the 74 cases admitted during the period of the outbreak. Myalgia, conjunctival suffusion, cough with hemoptysis, icterus, and oliguria were significantly more common in patients whose samples were determined positive by MAT. The presence of pulmonary signs and symptoms and renal failure were significantly associated with mortality in patients presumed to be suffering from leptospirosis.
authors.affiliation: Department of Microbiology, Byramjee Jeejeehoy Medical College, Maharashtra, India.
authors.forename: Renu
authors.initials: R
authors.lastname: Bharadwaj
authors.forename: Abhijit M
authors.initials: AM
authors.lastname: Bal
authors.forename: Suvarna A
authors.initials: SA
authors.lastname: Joshi
authors.forename: Anju
authors.initials: A
authors.lastname: Kagal
authors.forename: Sae S
authors.initials: SS
authors.lastname: Pol
authors.forename: Gajanan
authors.initials: G
authors.lastname: Garad
authors.forename: Vidya
authors.initials: V
authors.lastname: Arjunwadkar
authors.forename: Ravindra
authors.initials: R
authors.lastname: Katti
mesh_terms: D000328:Adult; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007919:Leptospira; D007922:Leptospirosis / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D014504:Urban Health