title: Treatment of metastatic breast cancer with liver transplantation.
abstract: Resection of liver metastases is accepted as an appropriate treatment for colorectal metastases in suitable patients. Liver transplant is not often used for malignant disease as there is a high incidence of undetectable micrometastases elsewhere and recurrence is likely. The effects of immunosuppression may also enhance the growth of malignant cells at other sites. We report a case where a young patient with undiagnosed breast cancer with axillary and liver metastases underwent liver transplantation and is effectively leading a normal life 33 months after transplant.
authors.affiliation: Academic Unit of Surgery, St. James's University Teaching Hospital, Leeds, West Yorkshire, United Kingdom. j.m.wilson@leeds.ac.uk
authors.forename: J M
authors.initials: JM
authors.lastname: Wilson
authors.forename: P
authors.initials: P
authors.lastname: Carder
authors.forename: S
authors.initials: S
authors.lastname: Downey
authors.forename: M H
authors.initials: MH
authors.lastname: Davies
authors.forename: J I
authors.initials: JI
authors.lastname: Wyatt
authors.forename: T G
authors.initials: TG
authors.lastname: Brennan
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000556:secondary; D018450:Disease Progression; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation; D020360:Neoadjuvant Therapy; D013997:Time Factors