Evidence for sexual difference in astrocytes of adult rat hippocampus.
We quantified the number of glial fibrillary acidic protein immunoreactive (GFAP-IR) astrocytes in the CA1 and CA3 areas of the adult rat hippocampus. The dorsal and ventral regions of the hippocampus were taken into account to estimate the GFAP-IR cells using unbiased stereological techniques. Males had a higher number of GFAP-IR astrocytes in the CA3 area, whereas females had more in the CA1 area. No sex difference was found between dorsal and ventral regions, although most GFAP-IR astrocytes were located in the dorsal hippocampus.
Conejo
Nélida M
NM
Laboratory of Psychobiology, School of Psychology, University of Oviedo, Oviedo, Spain. nelida@correo.uniovi.es
González-Pardo
Héctor
H
Pedraza
Carmen
C
Navarro
Francisco F
FF
Vallejo
Guillermo
G
Arias
Jorge L
JL
D000818:Animals; D001253:Astrocytes / Q000166:cytology* / Q000378:metabolism; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006624:Hippocampus / Q000166:cytology* / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012737:Sex Factors
D005904:Glial Fibrillary Acidic Protein