title: Substituted quinolines induce inhibition of proliferation of HTLV-1 infected cells.
abstract: Several quinolines were synthesized and evaluated against HTLV-1 infected cells. Some of them were able to inhibit HTLV-1 cell-growth at 10 microM. Some structure-activity relationships were observed.
authors.affiliation: Laboratoire de Pharmacognosie (associé au CNRS-BioCIS) Faculté de Pharmacie, Université de Paris-Sud, rue J. B. Clément, 92296 Châtenay-Malabry, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Fournet
authors.forename: Renaud
authors.initials: R
authors.lastname: Mahieux
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Fakhfakh
authors.forename: Xavier
authors.initials: X
authors.lastname: Franck
authors.forename: Reynald
authors.initials: R
authors.lastname: Hocquemiller
authors.forename: Bruno
authors.initials: B
authors.lastname: Figadère
mesh_terms: D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002472:Cell Transformation, Viral; D015490:HTLV-I Infections / Q000188:drug therapy*; D015368:Human T-lymphotropic virus 1 / Q000187:drug effects* / Q000254:growth & development; D006801:Humans; D011804:Quinolines / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013601:T-Lymphocytes / Q000166:cytology / Q000382:microbiology
chemical_list: D011804:Quinolines