title: Studies of serum total immunoglobulin E concentrations in atopic and non-atopic dogs.
abstract: The serum total immunoglobulin E (IgE) concentrations of two groups of atopic dogs and three groups of non-atopic dogs were compared. There was a wide range of concentrations with a high degree of overlap between the groups. The serum total IgE concentrations of a group of 15 non-atopic racing greyhounds were significantly higher than those of all the other groups. Atopic and non-atopic dogs receiving stringent parasite control treatments could not be differentiated on the basis of their serum total IgE concentrations. In the non-atopic dogs there was no correlation between their serum total IgE concentrations and the number of allergen-specific positive results obtained in an ELISA, or between their serum total IgE concentrations and their age.
authors.affiliation: Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH.
authors.forename: M A
authors.initials: MA
authors.lastname: Fraser
authors.forename: P E
authors.initials: PE
authors.lastname: McNeil
authors.forename: G
authors.initials: G
authors.lastname: Gettinby
mesh_terms: D000375:Aging / Q000276:immunology; D000485:Allergens / Q000276:immunology; D000818:Animals; D003876:Dermatitis, Atopic / Q000097:blood / Q000276:immunology* / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs / Q000145:classification / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male
chemical_list: D000485:Allergens; D007073:Immunoglobulin E