Transcriptional activation: getting a grip on condensed chromatin.
Chromosomal transcription involves the concerted action of enormous, multisubunit chromatin remodeling complexes. A recent study, however, suggests a different and surprising viewpoint in which these protein assemblies are quite dynamic and individual subunits play key roles in chromatin remodeling.
Peterson
Craig L
CL
Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Biotech 2, Suite 210, Worcester, MA 01605, USA. craig.Peterson@umassmed.edu
D000818:Animals; D016466:CHO Cells; D002843:Chromatin / Q000502:physiology*; D006224:Cricetinae; D014158:Transcription, Genetic / Q000502:physiology*
D002843:Chromatin