title: Solubilization of carbon nanotubes by Nafion toward the preparation of amperometric biosensors.
abstract: The ability to solubilize single-wall and multiwall carbon nanotubes (CNT) in the presence of the perfluorinated polymer Nafion is described. Such use of Nafion as a solubilizing agent for CNT overcomes a major obstacle for creating CNT-based biosensing devices. Their association with Nafion does not impair the electrocatalytic properties of CNT. The resulting CNT/Nafion modified glassy-carbon electrodes exhibit a strong and stable electrocatalytic response toward hydrogen peroxide. The marked acceleration of the hydrogen peroxide redox process is very attractive for the operation of oxidase-based amperometric biosensors, as illustrated for the highly selective low-potential (-0.05 V vs Ag/AgCl) biosensing of glucose. These findings open the door for using CNT in a wide range of chemical sensors and nanoscale electronic devices.
authors.affiliation: Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA. joewang@nmsu.edu
authors.forename: Joseph
authors.initials: J
authors.lastname: Wang
authors.forename: Mustafa
authors.initials: M
authors.lastname: Musameh
authors.forename: Yuehe
authors.initials: Y
authors.lastname: Lin
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004566:Electrodes; D005465:Fluorocarbon Polymers / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000737:chemistry; D012995:Solubility
chemical_list: D005465:Fluorocarbon Polymers; D037742:Nanotubes, Carbon; C040402:perfluorosulfonic acid; D006861:Hydrogen Peroxide; D010088:Oxidoreductases