title: FET-1: a novel W-linked, female specific gene up-regulated in the embryonic chicken ovary.
abstract: A differential expression screen for sex-determining genes in the embryonic chicken gonad revealed a novel gene called Female Expressed Transcript 1 (FET-1). Fluorescent in situ hybridization analysis mapped FET-1 to the female specific W chromosome. Whole mount in situ hybridization showed that FET-1 expression was restricted to females and up-regulated in the cortex of the left gonad during the sex-determining period. Female specific expression was also observed in the embryonic caudal somites, neural tube and waste collection ducts.
authors.affiliation: Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Kirsty J
authors.initials: KJ
authors.lastname: Reed
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Sinclair
mesh_terms: D000818:Animals; D002642:Chick Embryo; D005260:Female; D017404:In Situ Hybridization, Fluorescence; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D010053:Ovary / Q000196:embryology* / Q000378:metabolism; D012730:Sex Chromosomes; D015854:Up-Regulation
chemical_list: D008565:Membrane Proteins