[Prospects in the search for new biological agents to prevent tuberculosis].
Six biological specimens, including BCG obtained from Mycobacterium tuberculosis or animal tissues in accordance with an original procedure were studied. Their protective efficiency in tuberculosis infection was evaluated by the magnitude of allergic reactions and by pathological tissue changes 5 months after animal immunization and infection. The drug PKP-3 was found to be most effective and its further study is promising.
Kolomiets
V M
VM
Evglevskiĭ
A A
AA
Kovalenko
A M
AM
Timkova
E A
EA
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000818:Animals; D001500:BCG Vaccine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006168:Guinea Pigs; D014397:Tuberculosis, Pulmonary / Q000517:prevention & control*
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine