[New assumptions in the concept of vaccine prophylaxis of infantile infections].
An essential reduction in the incidence rate of six infantile infections within the Expanded Immunization Program was accompanied by occurrence of new problems in vaccine prophylaxis. 1. Vaccine-dependence--the reoccurrence of vaccine-prevented infections in those cases when vaccination was stopped. 2. A choice of strategy in the immune prophylaxis of poliomyelitis during the post-liquidation period bearing in mind the elimination of vaccine strains from the human population and a possible global refusal from vaccination. 3. Elaboration of regional programs for eliminating the measles in big territories. 4. Alteration of protective antigens Bordotella pertussis. The relationship of such alterations correlates with a rise in the Bordotella pertussis incidence rate with regard for multiple comprehensive vaccinations in the USA and Western Europe.
Semenov
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D001886:Bordetella pertussis / Q000276:immunology; D015331:Cohort Studies; D004165:Diphtheria / Q000453:epidemiology / Q000517:prevention & control*; D004168:Diphtheria Toxoid / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control*; D008458:Measles Vaccine / Q000008:administration & dosage*; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D011051:Poliomyelitis / Q000517:prevention & control*; D023321:Poliovirus Vaccines / Q000008:administration & dosage*; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D014611:Vaccination / Q000009:adverse effects; D014917:Whooping Cough / Q000453:epidemiology / Q000517:prevention & control*
D004168:Diphtheria Toxoid; D008458:Measles Vaccine; D010567:Pertussis Vaccine; D023321:Poliovirus Vaccines