title: Fluorous, chromatography-free Mitsunobu reaction.
abstract: [formula: see text] The reaction of secondary and primary alcohols with highly fluorinated 3,4,5-tris(5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-heptadecafluorododecan- 1-yloxy)benzoic acid in the presence of Ph3P and DIAD in THF at room temperature (fluorous Mitsunobu) resulted in a simple, chromatography-free isolation protocol with excellent yields (83-96%).
authors.affiliation: Department of Chemistry, Oakland University, 2200 N. Squirrel Rd., Rochester, Michigan 48309-4477, USA.
authors.forename: Marcin W
authors.initials: MW
authors.lastname: Markowicz
authors.forename: Roman
authors.initials: R
authors.lastname: Dembinski