[Sperm evaluation in testicular cancer patients before and after chemotherapy].
OBJECTIVE
Over the last 20 years treatment results of testicular cancer have improved. At present, up to 90% of patients are cured.


METHODS
Semen analysis has been performed in 50 patients before and 3, 6, 12, 12, 18, 24, 30 months after i.t.


METHODS
50 Patients with testicular cancer underwent chemotherapy based on cisplatin. Before and after treatment the semen analysis has been performed on each patients. The results of the patient groups have been compared to healthy group of men.


RESULTS
The quality of the semen is much worse in the group with cancer compared to healthy controls. The deepest impairment of the spermatogenesis has been found 3 mounts after chemotherapy.


CONCLUSIONS
Orchidectomy has no influence on sperm parameters. Semen analysis revealed normospermia in 30% of the patients. 30 months after chemotherapy.
Demkow
Tomasz
T
Kliniki Nowotworów Układu Moczowego Centrum Onkologii-Instytutu w Warszawie.
Faundez
Ricardo
R
Kamoda
Jacek
J
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D016022:Case-Control Studies; D002945:Cisplatin / Q000009:adverse effects; D006801:Humans; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D012661:Semen / Q000187:drug effects* / Q000378:metabolism; D013091:Spermatogenesis; D013094:Spermatozoa / Q000187:drug effects* / Q000378:metabolism; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000503:physiopathology*; D013997:Time Factors; D016896:Treatment Outcome
D002945:Cisplatin