title: Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection.
abstract: The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partial-onset seizures. Detailed magnetic resonance imaging (MRI) studies were normal. Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation.
authors.affiliation: Texas Comprehensive Epilepsy Program, Department of Neurology, University of Texas-Houston Medical School, Houston, Texas, USA. y2ng@chw.edu
authors.forename: Yu-tze
authors.initials: YT
authors.lastname: Ng
authors.forename: Howard L
authors.initials: HL
authors.lastname: Kim
authors.forename: James W
authors.initials: JW
authors.lastname: Wheless
mesh_terms: D001931:Brain Mapping; D002675:Child, Preschool; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D009421:Nervous System Malformations / Q000175:diagnosis / Q000601:surgery; D010296:Parietal Lobe / Q000002:abnormalities / Q000601:surgery*; D013226:Status Epilepticus / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome