title: Osteogenesis imperfecta with bleeding diathesis.
abstract: Osteogenesis imperfecta (OI) is a disorder of type 1 collagen synthesis with varied complications in form of brittle bones, hearing loss, dental, skin, and ocular changes. Osteogenesis imperfecta may have bleeding diathesis rarely due to defective vascular integrity for the same reason. Here we come across a rare case of Sillence type IB Osteogenesis imperfecta with bleeding in the form of repeated epistaxis and petechial rash, which seem to have a collagenous link.
authors.affiliation: Department of Pediatrics, Deen Dayal Upadhyaya Hospital, New Delhi, India.
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Mondal
authors.forename: Umang
authors.initials: U
authors.lastname: Mann
authors.forename: Mamta
authors.initials: M
authors.lastname: Sharma
mesh_terms: D002648:Child; D004844:Epistaxis / Q000209:etiology; D005076:Exanthema / Q000209:etiology; D006474:Hemorrhagic Disorders / Q000209:etiology*; D006801:Humans; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications*