The membrane domain of SpoIIIE is required for membrane fusion during Bacillus subtilis sporulation.
During Bacillus subtilis sporulation, SpoIIIE is required for both postseptational chromosome segregation and membrane fusion after engulfment. Here we demonstrate that SpoIIIE must be present in the mother cell to promote membrane fusion and that the N-terminal membrane-spanning segments constitute a minimal membrane fusion domain, as well as direct septal localization.
Sharp
Marc D
MD
Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0349, USA.
Pogliano
Kit
K
D001412:Bacillus subtilis / Q000737:chemistry / Q000166:cytology / Q000502:physiology*; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D002455:Cell Division; D004269:DNA, Bacterial / Q000378:metabolism; D008561:Membrane Fusion / Q000502:physiology*; D009154:Mutation; D013171:Spores, Bacterial / Q000502:physiology
D001426:Bacterial Proteins; D004269:DNA, Bacterial; C030069:spore-specific proteins, Bacillus