Osteogenesis imperfecta with bleeding diathesis.
Osteogenesis imperfecta (OI) is a disorder of type 1 collagen synthesis with varied complications in form of brittle bones, hearing loss, dental, skin, and ocular changes. Osteogenesis imperfecta may have bleeding diathesis rarely due to defective vascular integrity for the same reason. Here we come across a rare case of Sillence type IB Osteogenesis imperfecta with bleeding in the form of repeated epistaxis and petechial rash, which seem to have a collagenous link.
Mondal
Rakesh K
RK
Department of Pediatrics, Deen Dayal Upadhyaya Hospital, New Delhi, India.
Mann
Umang
U
Sharma
Mamta
M
D002648:Child; D004844:Epistaxis / Q000209:etiology; D005076:Exanthema / Q000209:etiology; D006474:Hemorrhagic Disorders / Q000209:etiology*; D006801:Humans; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications*