title: Trace analysis of peroxide-based explosives.
abstract: The first method for quantitative trace analysis of peroxide-based explosives is described. A reversed-phase high-performance liquid chromatography method with post-column UV irradiation and fluorescence detection for the analysis of triacetone triperoxide (TATP) and hexamethylene triperoxide diamine (HMTD) has been developed. After separation, the analytes are degraded photochemically to hydrogen peroxide, which is subsequently determined on the basis of the peroxidase-catalyzed oxidation of p-hydroxyphenylacetic acid to the fluorescent dimer. This two-step reaction scheme in combination with the respective blanks (photochemical reactor switched off) provides for high selectivity. The limits of detection were 2 x 10(-6) mol/L for both TATP and HMTD, respectively. The method has been applied to the analysis of real samples.
authors.affiliation: Department of Chemical Analysis and MESA+ Research Institute, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.
authors.forename: Rasmus
authors.initials: R
authors.lastname: Schulte-Ladbeck
authors.forename: Peter
authors.initials: P
authors.lastname: Kolla
authors.forename: Uwe
authors.initials: U
authors.lastname: Karst
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods / Q000592:standards; D005107:Explosions; D010545:Peroxides / Q000032:analysis*
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D010545:Peroxides; C058103:hexamethylenetriperoxidediamine