[Consciousness disturbance caused by iodoform absorption in a patient with decubitus ulcer topically treated with iodoform-gauze].
A 76-year-old man with supranuclear palsy, developed consciousness disturbance followed by the treatment of decubitus ulcer in the sacral region using iodoform-gauze. He was semicoma and tachycardia. His pupils were miotic and light reflexes were absent. EEG demonstrated diffuse and random slow activities. Plasma concentration of free iodine was high (151 micrograms/dl), but the other laboratory findings including thyroid functions were normal. He was diagnosed as suffering from iodoform poisoning. The symptoms and laboratory abnormalities of the patient recovered soon after the removal of iodoform-gauze. Although iodoform has been widely used for the treatment of wounds, there are few case reports of its side effects, such as consciousness disturbance, delirium, headache and tachycardia.
Tada
Masayoshi
M
Department of Neurology, Akita Red Cross Hospital, 222-1 Nawashirosawa, Saruta, Kamikitate, Akita-shi, Akita 010-1495, Japan.
Tada
Mari
M
Ishiguro
Hideaki
H
Hirota
Kouichi
K
D000208:Acute Disease; D000368:Aged; D003244:Consciousness Disorders / Q000139:chemically induced*; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000506:poisoning*; D008297:Male; D003668:Pressure Ulcer / Q000188:drug therapy*; D013494:Supranuclear Palsy, Progressive / Q000150:complications
D006847:Hydrocarbons, Iodinated; C010473:iodoform