title: Theophylline: new perspectives for an old drug.
authors.affiliation: Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College, Dovehouse Street, London SW3 6LY, UK. p.j.barnes@ic.ac.uk
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Barnes
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D001993:Bronchodilator Agents / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D015870:Gene Expression / Q000187:drug effects / Q000276:immunology; D006655:Histone Deacetylases / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007249:Inflammation / Q000276:immunology; D016753:Interleukin-10 / Q000276:immunology; D008657:Metabolic Clearance Rate; D008967:Molecular Biology; D018579:Patient Selection; D010726:Phosphodiesterase Inhibitors / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D018047:Receptors, Purinergic P1 / Q000187:drug effects; D013806:Theophylline / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D001993:Bronchodilator Agents; D010726:Phosphodiesterase Inhibitors; D018047:Receptors, Purinergic P1; D016753:Interleukin-10; D013806:Theophylline; D006655:Histone Deacetylases