title: [Hyperhomocysteinemia and thrombosis: clinical case and literature's review].
abstract: Patients with homocystinuria have an increased risk for both venous and artherial thrombosis but it has been found that even moderate increase in homocysteine levels are associated with heightened risk of thromboembolism. The Authors report a case of juvenile vasculopathy in a patient with hyperomocysteinemia. In this case the patient presented both venous and artherial thromboembolism in the absence of the most important risk factors. The opportunity is stressed to perform clinical tests for the correct diagnosis of hyperhomocysteinemia because it is possible, with the use of folic acid and vitamin B12, to correct the elevated levels of homocysteine.
authors.affiliation: Insegnamento di semeiotica chirurgica e metodologia clinica, Divisione di Chirurgia Generale, Dipartimento di Scienze Chirurgiche, Università degli Studi La Sapienza, Roma.
authors.forename: F
authors.initials: F
authors.lastname: Stio
authors.forename: G
authors.initials: G
authors.lastname: Guerriero
authors.forename: S
authors.initials: S
authors.lastname: Ferri
authors.forename: R P
authors.initials: RP
authors.lastname: Iachetta
authors.forename: M
authors.initials: M
authors.lastname: Scona
authors.forename: R E
authors.initials: RE
authors.lastname: Stio
authors.forename: D
authors.initials: D
authors.lastname: Feroci
mesh_terms: D000328:Adult; D005263:Femoral Artery; D006710:Homocysteine / Q000097:blood; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008297:Male; D011150:Popliteal Artery; D013923:Thromboembolism / Q000209:etiology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D006710:Homocysteine