title: Neuropsychological Outcome in Children after Frontal Lobe Epilepsy Surgery.
abstract: We investigated the neuropsychological performance of children with frontal lobe epilepsy (FLE, n = 12) before and 1 year after surgery. Children with temporal lobe epilepsy (TLE, n = 12) were included as control group. Preoperatively, children with FLE had a significantly higher IQ than children with TLE, but were significantly more often impaired in manual motor coordination. Postoperatively, both groups improved in attention, short-term and long-term memory, and manual coordination, although the latter was not significant. Neuropsychological outcome in FLE patients was not better in seizure-free patients than in patients with continuing seizures. To avoid deterioration in language functions of patients in whom surgery involved left area 44, correspondence of results in cortical stimulation and intracarotid amytal test may be essential. All in all, our data indicate a favorable cognitive outcome in children 1 year after frontal lobe surgery.
authors.affiliation: University Hospital of Epileptology, Bonn, Germany
authors.forename: M
authors.initials: M
authors.lastname: Lendt
authors.forename: U
authors.initials: U
authors.lastname: Gleissner
authors.forename: C
authors.initials: C
authors.lastname: Helmstaedter
authors.forename: R
authors.initials: R
authors.lastname: Sassen
authors.forename: H
authors.initials: H
authors.lastname: Clusmann
authors.forename: C E.
authors.initials: CE
authors.lastname: Elger