[Acute exacerbation of interstitial pneumonia associated with active systemic lupus erythematosus in a patient with rheumatoid arthritis].
A 36-year-old woman with rheumatoid arthritis was admitted to our hospital for evaluation of newly developed active systemic lupus erythematosus (SLE). After hospitalization, she showed progressive respiratory failure. Chest CT revealed exacerbation of interstitial pneumonia, showing acute development of air-space consolidation and ground-glass opacity in addition to intensified reticular shadows. Administration of high-dose corticosteroids and cyclosporine A resulted in recovery from respiratory failure, accompanied by obvious improvement in the chest radiographs and CT, as demonstrated by the disappearance of air-space consolidation and ground-glass opacity. Clinically, the exacerbation of her interstitial pneumonia was compatible with acute lupus pneumonitis, a rare complication with active SLE.
Sadakata
Ayaka
A
Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Yamaguchi
Masao
M
Misaki
Yoshikata
Y
Komiya
Akiko
A
To
Yasuo
Y
Iikura
Motoyasu
M
Yamada
Hirokazu
H
Tanaka
Ryoichi
R
Dohi
Makoto
M
Yamamoto
Kazuhiko
K
D000208:Acute Disease; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000503:physiopathology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*