[Calcimimetics as a new chance for effective treatment of calcium metabolism disturbances].
Physiological principles are presented of calcium receptor (CaR) as well as agents affecting the receptor, defined as calcimimetics. Positive influence of type 1 and type 2 calcimimetics on calcium metabolism is discussed. The clinical indications for calcimimetics, especially type 2, in the future, seem to be hypercalcemia in the course of primary and secondary hyperparathyroidism as well as hypercalcemia in patients with parathyroid carcinoma.
Nowak
Zbigniew
Z
Klinika Nefrologii ze Stacja Dializ Centralnego Szpitala Klinicznego WAM w Warszawie.
Laudański
Krzysztof
K
D002118:Calcium / Q000819:agonists* / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy; D007668:Kidney / Q000378:metabolism; D010280:Parathyroid Glands / Q000378:metabolism; D010282:Parathyroid Neoplasms / Q000188:drug therapy; D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface / Q000187:drug effects*
D002135:Calcium-Binding Proteins; D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface; D002118:Calcium