title: Preresponse cues reduce the impairing effects of alcohol on the execution and suppression of responses.
abstract: The present study examined the effects of alcohol on the ability to execute and inhibit behavior in a context in which preliminary information signaled the likelihood that a response should be executed or suppressed. Social drinkers (N = 12) performed a cued go/no-go task that required quick responses to go targets and suppression of responses to no-go targets. Performance was tested under 3 doses of alcohol: 0.65 g/kg, 0.45 g/kg, and 0.0 g/kg (placebo). Alcohol had no effect on inhibition and execution when cues correctly signaled these actions. By contrast, alcohol impaired inhibition and execution in a dose-dependent manner when cues incorrectly signaled actions. These findings are consistent with a resource limitation account of alcohol impairment.
authors.affiliation: Department of Psychology, University of Kentucky, Lexington 40506-0044, USA.
authors.forename: Cecile A
authors.initials: CA
authors.lastname: Marczinski
authors.forename: Mark T
authors.initials: MT
authors.lastname: Fillmore
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000523:psychology; D002492:Central Nervous System Depressants / Q000097:blood / Q000494:pharmacology*; D003216:Conditioning, Operant / Q000187:drug effects*; D003463:Cues; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009949:Orientation; D011930:Reaction Time / Q000187:drug effects
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol