title: HLA typing does not predict REM sleep behaviour disorder and hallucinations in Parkinson's disease.
abstract: HLA-DR2 haplotype and DQ1 DNA alleles, characterizing 90 to 100% of all narcoleptic patients, were found to be equally distributed in 20 Parkinson's disease (PD) patients with early hallucinations, rapid eye movement (REM) sleep-related behaviour disturbances (RBD), and sleep onset in REM (SOREM), and in 20 PD patients without hallucinations, despite 10 to 15 years of treatment, and no RBD or SOREM.
authors.affiliation: Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Onofrj
authors.affiliation: Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Anna Lisa
authors.initials: AL
authors.lastname: Luciano
authors.affiliation: Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Diego
authors.initials: D
authors.lastname: Iacono
authors.affiliation: Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Astrid
authors.initials: A
authors.lastname: Thomas
authors.affiliation: Department of Oncology and Neuroscience, Movement Disorders Center, Neurophysiopathology, Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Stocchi
authors.affiliation: Regional Center for Immunohaematology and Tissue Typing, National Council of Research, L'Aquila, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Papola
authors.affiliation: Regional Center for Immunohaematology and Tissue Typing, National Council of Research, L'Aquila, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Adorno
authors.affiliation: Institute of Medical Statistics. Università G. D'Annunzio, Chieti-Pescara, Italy.
authors.forename: Rocco
authors.initials: R
authors.lastname: Di Mascio
mesh_terms: D000368:Aged; D002352:Carrier Proteins / Q000235:genetics; D005260:Female; D015802:HLA-DR2 Antigen / Q000235:genetics; D006212:Hallucinations / Q000175:diagnosis / Q000235:genetics*; D006239:Haplotypes; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D018832:Molecular Chaperones; D010300:Parkinson Disease / Q000235:genetics*; D020187:REM Sleep Behavior Disorder / Q000175:diagnosis / Q000235:genetics*; D012494:Sampling Studies
chemical_list: D002352:Carrier Proteins; D015802:HLA-DR2 Antigen; D018832:Molecular Chaperones; C108175:TOR1A protein, human; C491547:TOR1B protein, human