Animal transgenesis: recent data and perspectives.
Gene transfer to generate transgenic animals is used more and more to study gene regulation and function. It is also an essential tool to prepare pharmaceuticals or pig organs for transplantation to humans. It is also expected to be a potent way to generate farm animals having traits that cannot emerge by conventional selection. During the last few years, the different techniques to generate transgenic animals and obtain a well-controlled expression of the transgenes have been quite significantly improved. This paper is a brief summary of the most recent relevant data in this field.
Houdebine
Louis-Marie
LM
Biology of Development and Biotechnology, Institut National de la Recherche Agronomique, 78352 Jouy-en-Josas, France. houdebine@biotec.jouy.inra.fr
D000818:Animals; D030801:Animals, Genetically Modified; D005786:Gene Expression Regulation; D018014:Gene Transfer Techniques; D014162:Transfection