title: The use of computed tomography for the diagnosis of acute appendicitis in children does not influence the overall rate of negative appendectomy or perforation.
abstract: BACKGROUND
  Computed tomography (CT) has been used more frequently to diagnose acute appendicitis in children. The purpose of this study was to determine whether the use of CT has any influence on negative appendectomy or perforation rates.
  
  
  METHODS
  Review of a prospective database of children having appendectomy for suspected acute appendicitis. Negative appendectomy and perforation rates were determined by correlation with final pathology reports.
  
  
  RESULTS
  Eighty-five consecutive patients underwent appendectomy for the suspicion of acute appendicitis. The overall negative appendectomy rate was 17.6%, being 19.4% in females and 16.6% in males (p = 0.75). The overall accuracy, sensitivity and positive predictive value of CT were 75%, 91%, and 81%, respectively. Patients that had CT did not have a significantly lower rate of negative appendectomy (17.9% vs. 19.3%, p > 0.99) or perforation (26% vs. 17%; p = 0.53).
  
  
  CONCLUSIONS
  The use of CT for the diagnosis of appendicitis in children does not change the negative appendectomy rate. Results of studies performed in adults may not be extrapolated to the evaluation of children with suspected acute appendicitis.
authors.affiliation: Department of Surgery, New York-Presbyterian Hospital and Weill Medical College of Cornell University, New York, NY 10021, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Weyant
authors.forename: S R
authors.initials: SR
authors.lastname: Eachempati
authors.forename: M A
authors.initials: MA
authors.lastname: Maluccio
authors.forename: N
authors.initials: N
authors.lastname: Spigland
authors.forename: L J
authors.initials: LJ
authors.lastname: Hydo
authors.forename: P S
authors.initials: PS
authors.lastname: Barie
mesh_terms: D000293:Adolescent; D001062:Appendectomy; D001064:Appendicitis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed