Anion receptors: a new class of amide/quaternized amine macrocycles and the chelate effect.
A new class of tetraamide macrocyclic receptors for anions with two quaternized amine functionalities exhibited higher affinities for anions compared with the corresponding neutral amides. In two crystal structures of halide complexes of the prototypes with phenyl and pyridine spacers, the anions are held by hydrogen bonding with the amide hydrogens. The pyridine analogues display higher affinities in general than the phenyl systems, a phenomenon which is attributed to the anion version of the chelate effect.
Hossain
Md Alamgir
MA
Department of Chemistry, University of Kansas, Lawrence 66045, USA.
Kang
Sung Ok
SO
Powell
Douglas
D
Bowman-James
Kristin
K