title: Variability in the incidence of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infection among young injecting drug users in New York City.
abstract: Cohort studies of young (aged 18-30 years) injecting drug users recruited in 1997-1999 in the Harlem and Lower East Side areas of New York City, New York, were used to assess the incidence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). The authors found that HIV incidence was low at both sites: 0.8/100 person-years at the Harlem site and 0/100 person-years at the Lower East Side site. In contrast, HBV incidence was moderate (12.2/100 person-years) at the Harlem site and high (30.7/100 person-years) at the Lower East Side site. Similarly, HCV incidence was moderate (9.3/100 person-years) at the Harlem site and high (34.0/100 person-years) at the Lower East Side site. Results show that high rates of HBV and HCV transmission do not imply high rates of HIV transmission, even within an area of high HIV seroprevalence.
authors.affiliation: Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York, NY 10003, USA. dcdesjarla@aol.com
authors.forename: Don C
authors.initials: DC
authors.lastname: Des Jarlais
authors.forename: Theresa
authors.initials: T
authors.lastname: Diaz
authors.forename: Theresa
authors.initials: T
authors.lastname: Perlis
authors.forename: David
authors.initials: D
authors.lastname: Vlahov
authors.forename: Carey
authors.initials: C
authors.lastname: Maslow
authors.forename: Mary
authors.initials: M
authors.lastname: Latka
authors.forename: Russell
authors.initials: R
authors.lastname: Rockwell
authors.forename: Vincent
authors.initials: V
authors.lastname: Edwards
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Friedman
authors.forename: Edgar
authors.initials: E
authors.lastname: Monterroso
authors.forename: Ian
authors.initials: I
authors.lastname: Williams
authors.forename: Richard S
authors.initials: RS
authors.lastname: Garfein
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006509:Hepatitis B / Q000453:epidemiology* / Q000635:transmission; D006526:Hepatitis C / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D015994:Incidence; D007407:Interviews as Topic; D008297:Male; D009519:New York City / Q000453:epidemiology; D012309:Risk-Taking; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000821:virology*