title: HPLC-NMR/HPLC-MS analysis of the bark extract of Stauranthus perforatus.
abstract: A combination of HPLC-MS and HPLC-NMR techniques has been used to analyse the cytotoxic fractions of the dichloromethane extract of bark of Stauranthus perforatus. Six furanocoumarins (byakangelicol, heraclenin, heraclenol, imperatorin, isopimpinellin and xanthotoxin) and nine quinoline alkaloids (two known compounds, veprisine and 5-hydroxy-1-methyl-2-phenyl-4-quinolone, along with seven novel compounds, stauranthine, 3',4'-dihydroxy-3',4'-dihydroveprisine, 3',4'-dihydroxy-3',4'-dihydrostauranthine, 3',6'-dihydroxy-3',6'-dihydroveprisine, 3',6'-dihydroxy-3',6'-dihydrostauranthine, 6'-hydroxy-3'-ketoveprisine and 6'-hydroxy-3'-ketostauranthine) have been identified in the fractions.
authors.affiliation: Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu
authors.forename: William N
authors.initials: WN
authors.lastname: Setzer
authors.forename: Bernhard
authors.initials: B
authors.lastname: Vogler
authors.forename: Robert B
authors.initials: RB
authors.lastname: Bates
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Schmidt
authors.forename: Christopher W
authors.initials: CW
authors.lastname: Dicus
authors.forename: Pichaya
authors.initials: P
authors.lastname: Nakkiew
authors.forename: William A
authors.initials: WA
authors.lastname: Haber
mesh_terms: D000470:Alkaloids / Q000032:analysis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D011564:Furocoumarins / Q000032:analysis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D011804:Quinolines / Q000032:analysis / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D011564:Furocoumarins; D010936:Plant Extracts; D011804:Quinolines