[Effective transarterial neoadjuvant chemotherapy with paclitaxel (TXL) in a case of locally advanced breast cancer].
The patient was a 49-year-old woman who had locally advanced breast cancer with skin invasion. She was placed on neoadjuvant weekly systemic chemotherapy of TXL (65 mg/m2) and ADM (20 mg/m2). After systemic chemotherapy, she underwent 2 courses of transarterial neoadjuvant chemotherapy of TXL (day 1, 8, 15). We administered TXL (45 mg/m2) into the subclavian artery and TXL (20 mg/m2) into the internal thoracic artery. Although she experienced grade 3 leukopenia during systemic chemotherapy, she experienced only grade 2 alopecia and grade 1 nausea during transarterial chemotherapy. After chemotherapy, she underwent radical mastectomy. We report herein a case in which transarterial neoadjuvant chemotherapy with TXL was effective.
Koga
Yoshikatsu
Y
Dept. of Surgery, Miyazaki Prefectural Nobeoka Hospital.
Ohchi
Tetsufumi
T
Kudo
Shunsuke
S
Ogata
Kenichi
K
Nakamura
Takeshi
T
Ishiodori
Hiroyuki
H
Ochiai
Takashi
T
Muranaka
Takahiro
T
Ishihara
Akira
A
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D015409:Mastectomy, Radical; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D017239:Paclitaxel / Q000008:administration & dosage*; D013348:Subclavian Artery; D013895:Thoracic Arteries
D000972:Antineoplastic Agents, Phytogenic; D004317:Doxorubicin; D017239:Paclitaxel