Ehrlichiosis optic neuritis.
OBJECTIVE
To describe a case of ehrlichiosis optic neuritis.


METHODS
Single observational case report.


METHODS
A 41-year-old woman with symptoms and clinical and imaging signs consistent with optic neuritis presented to a tertiary care academic center for comprehensive neuro-ophthalmic evaluation. Main outcome measures included preoptic and postoptic neuritis polyvalent ehrlichiosis titers and magnetic resonance imaging (MRI) of orbits with gadolinium.


RESULTS
Ehrlichiosis titers drawn 11 days before onset of eye symptoms were negative. Titers drawn 7 days after symptoms began were positive. The optic nerve enhanced with gadolinium on MRI.


CONCLUSIONS
Ehrlichiosis can cause optic neuritis and should be considered in patients with optic neuritis after a febrile, flu-like illness in an endemic area.
Lee
Michael S
MS
Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. leem4@ccf.org
Goslee
Timothy E
TE
Lessell
Simmons
S
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood; D004318:Doxycycline / Q000627:therapeutic use; D004536:Ehrlichia / Q000276:immunology; D016873:Ehrlichiosis / Q000150:complications* / Q000175:diagnosis; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000382:microbiology; D008279:Magnetic Resonance Imaging; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D004318:Doxycycline