title: Engineering redox functions in a nucleic acid binding protein.
abstract: A nucleic acid binding protein, rop, has conserved topology with a number of redox proteins; this is exploited to engineer haem binding, expanding its function as a redox protein.
authors.affiliation: Department of Biological Sciences, Biochemistry Building, Imperial College, London, UK SW7 2AY.
authors.forename: Jon R
authors.initials: JR
authors.lastname: Wilson
authors.forename: Daren J
authors.initials: DJ
authors.lastname: Caruana
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Gilardi
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry; D001665:Binding Sites; D004563:Electrochemistry / Q000379:methods; D006418:Heme / Q000737:chemistry; D010084:Oxidation-Reduction; D011487:Protein Conformation; D015202:Protein Engineering / Q000379:methods*; D016601:RNA-Binding Proteins / Q000737:chemistry*; D017186:Titrimetry
chemical_list: D001426:Bacterial Proteins; D016601:RNA-Binding Proteins; C054243:Rop protein, ColE1 plasmid; D006418:Heme