title: Multiple sclerosis: report on 200 cases from Iran.
abstract: Clinical findings of 200 patients in Iran with definite multiple sclerosis (MS) according to Poser et al.'s criteria and positive findings on magnetic resonance imaging (MRI) have been reviewed. The clinical course was relapsing-remitting (RR) for 88%, primary progressive (PP) for 7% and secondary progressive (SP) for 5% of cases. The mean age of onset was 27 +/- 7.4 years for the whole group and 37.1 +/- 8.8 years for PPMS. The gender ratio was 2.5:1 female:male. Involvement of the pyramidal system was the most common mode of presentation. Five per cent of patients had positive family history for the disease, 14% of patients had benign MS and 12% with disease duration longer than five years had an Expanded Disability Status Scale < or = 2. The optico-spinal form was not a common form of presentation in the group.
authors.affiliation: Shahid Beheshtie University of Medical Sciences, Department of Neurology, Loghman Hospital, Kamalie Street, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Kalanie
authors.forename: Kurosh
authors.initials: K
authors.lastname: Gharagozli
authors.forename: Amir Reza
authors.initials: AR
authors.lastname: Kalanie
mesh_terms: D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D020528:Multiple Sclerosis, Chronic Progressive / Q000453:epidemiology* / Q000473:pathology; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000453:epidemiology* / Q000473:pathology; D011712:Pyramidal Tracts / Q000473:pathology; D017678:Sex Distribution