Botryomycosis in an HIV-positive subject.
A 28-year-old male AIDS patient with generalized painful skin ulcers, fever and malaise presented to us. The differential diagnosis included varicella zoster infection, herpes simplex infection, actinomycosis, sporotrichosis and botryomycosis. Histopathology revealed clusters of gram-positive coccoid bacteria in the deep dermis, surrounded by a mixed dense inflammatory infiltrate. A bacterial culture grew Staphylococcus aureus. Viral cultures remained negative. Based on these findings botryomycosis was diagnosed. Large lesions were excised surgically and with antimicrobial therapy all skin symptoms disappeared. We discuss this case with reference to a short review of the literature on botryomycosis in relation to HIV infection.
de Vries
H J C
HJ
Department of Dermatology, Academic Medical Centre, University of Amsterdam, POB 22700, 1100 DE, Amsterdam, The Netherlands. h.j.devries@amc.uva.nl
van Noesel
C J M
CJ
Hoekzema
R
R
Hulsebosch
H J
HJ
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology*; D000328:Adult; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D008297:Male; D013207:Staphylococcal Skin Infections / Q000276:immunology*; D013211:Staphylococcus aureus