title: Clinicopathologic features of ileocolonic malignant lymphoma: analysis according to colonoscopic classification.
abstract: BACKGROUND
  The aims of this study were to classify primary ileocolonic lymphomas according to colonoscopic findings and to determine the clinicopathologic relationship according to classes.
  
  
  METHODS
  Thirty-two patients (22 men, 10 women; age range 29 to 75 years) with primary malignant lymphoma of the terminal ileum and/or colorectum were studied. The clinicopathologic features were evaluated according to colonoscopic findings.
  
  
  RESULTS
  Thirty-six lesions in 32 patients were endoscopically classified as follows: fungating (14, 39%), ulcerofungating (11, 31%), infiltrative (5, 14%), ulceroinfiltrative (4, 11%), and ulcerative (2, 6%). Location of the lesions was as follows: terminal ileum, 15 (42%); colorectum, 14 (39%); both regions, 7 (19%). The most common histopathologic types were diffuse large cell (22, 69%) and large cell immunoblastic (5, 16%). There was no relationship between the endoscopic findings and histologic types. In 9 patients (28%), the clinical manifestation was intussusception, and all were found endoscopically to have the fungating type lesion.
  
  
  CONCLUSIONS
  Primary ileocolonic lymphomas can be classified endoscopically into fungating, ulcerative, infiltrative, ulcerofungating, and ulceroinfiltrative types. Among these, fungating and ulcerofungating are the most frequent. Intussusception is a common clinical finding in ileocolonic lymphomas, occurring mainly in patients with the fungating type of lesion.
authors.affiliation: Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Seung-Jae
authors.initials: SJ
authors.lastname: Myung
authors.forename: Kwang Ro
authors.initials: KR
authors.lastname: Joo
authors.forename: Suk-Kyun
authors.initials: SK
authors.lastname: Yang
authors.forename: Hwoon-Yong
authors.initials: HY
authors.lastname: Jung
authors.forename: Hye-Sook
authors.initials: HS
authors.lastname: Chang
authors.forename: Hyun Ju
authors.initials: HJ
authors.lastname: Lee
authors.forename: Weon-Seon
authors.initials: WS
authors.lastname: Hong
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Young Il
authors.initials: YI
authors.lastname: Min
authors.forename: Hee Cheol
authors.initials: HC
authors.lastname: Kim
authors.forename: Chang Sik
authors.initials: CS
authors.lastname: Yu
authors.forename: Jin Cheon
authors.initials: JC
authors.lastname: Kim
authors.forename: Jung-Sun
authors.initials: JS
authors.lastname: Kim
mesh_terms: D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000145:classification / Q000175:diagnosis*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000145:classification / Q000175:diagnosis*; D007082:Ileum / Q000473:pathology; D008223:Lymphoma / Q000145:classification / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000145:classification / Q000175:diagnosis*; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000145:classification / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged