[Predictive parameters of infectiologic complications in patients after TIPSS].
OBJECTIVE
To define predictive parameters of a complicated clinical course after the TIPSS procedure.


METHODS
Blood cultures were drawn prospectively in 41 patients from a central line and from the portal venous blood before stent placement as well as from the central line 20 min after intervention. C-reactive protein (CRP) (mg/dl) and white blood cell count (WBC,/microl) on the day of TIPSS-procedure (d0), the first (d1) and seven (d7) days after TIPSS were compared in patients with a complicated clinical course (spontaneous bacterial peritonitis,pneumonia,sepsis; group I) to patients without clinical complications (group II) RESULTS: Group I showed a significant increase in CRP (d0: 1.8+/-1.0; d1: 3.2+/-1.5; d7: 4.3+/-3.2), and white blood cell count (d0: 7700+/-2600; d1: 10800+/-2800; d7: 7500+/-1800) on the first day after TIPSS-procedure in comparison to group II (CRP: d0: 1.6+/-0.6; d1: 1.8+/-1.0; d7: 1.9+/-0.6. WBC: d0: 6900+/-1500; d1: 8000+/-1600; d7: 7600+/-1400). Microbiological analysis showed in 12% skin or oral flora in the last sample.


CONCLUSIONS
The course of CRP and WBC-count during the first week after TIPSS procedure may indicate patients with a potential risk of a complicated clinical course.
Cohnen
M
M
Institut für Diagnostische Radiologie, Universitätsklinikum Düsseldorf.
Lüthen
R
R
Däubener
W
W
Saleh
A
A
Bode
J
J
Häussinger
D
D
Mödder
U
U
D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000175:diagnosis* / Q000276:immunology; D001424:Bacterial Infections / Q000175:diagnosis* / Q000276:immunology; D001431:Bacteriological Techniques; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007958:Leukocyte Count; D008103:Liver Cirrhosis / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000175:diagnosis / Q000276:immunology; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000276:immunology; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011237:Predictive Value of Tests; D015607:Stents; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000276:immunology
D002097:C-Reactive Protein