[Resistant starches and immune system].
Different absorbtion level is inherent capacities for natural, resistant and hydrolized starches to regulate a volume of non-hydrolyzed starches in colon. This regulates an interaction with intestinal microflora to produce the short chain fatty acids and other bio-active compounds. The T- and B-lymphocyte receptors are targets for starches to disrupt the number and density of plasma membrane receptors CD3, CD4, and CD8. All starches regulate the expression of adhesion molecules LFA-1 and ICAM-1, as well as receptor Mac-1. Maize starch increases the level of spontaneous and ceramide-dependent apoptosis in thymic and spleen cells of experimental animals.
Sotnikova
E V
EV
Martynova
E A
EA
Gorbacheva
E V
EV
Gapparov
M M
MM
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D017252:CD3 Complex / Q000378:metabolism; D015704:CD4 Antigens / Q000378:metabolism; D016827:CD8 Antigens / Q000378:metabolism; D003106:Colon / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D007107:Immune System / Q000502:physiology*; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000382:microbiology; D016169:Lymphocyte Function-Associated Antigen-1 / Q000378:metabolism; D013154:Spleen / Q000276:immunology / Q000473:pathology; D013213:Starch / Q000378:metabolism*
D017252:CD3 Complex; D015704:CD4 Antigens; D016827:CD8 Antigens; D005227:Fatty Acids; D016169:Lymphocyte Function-Associated Antigen-1; D018799:Intercellular Adhesion Molecule-1; D013213:Starch