Proline-catalyzed asymmetric alpha-amination of aldehydes and ketones--an astonishingly simple access to optically active alpha-hydrazino carbonyl compounds.
Duthaler
Rudolf O
RO
Novartis Institutes for Biomedical Research, Postfach, 4002 Basel, Switzerland. rudolf.duthaler@pharma.novartis.com
D000447:Aldehydes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D011392:Proline / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D000588:Amines; D007659:Ketones; D011392:Proline