title: Measurement of adhesive forces between individual Staphylococcus aureus MSCRAMMs and protein-coated surfaces by use of optical tweezers.
abstract: The force required to rupture bonds between individual Staphylococcus aureus MSCRAMMs and surfaces coated with extracellular matrix molecules has been quantified by using optical tweezers. The observed binding forces between fibrinogen or fibronectin and S. aureus MSCRAMMs occurred as an approximate integer multiple of 20 or 25 pN, respectively.
authors.affiliation: Department of Bioengineering, Rice University, Houston, Texas 77251-1892, USA.
authors.forename: Kathryn H
authors.initials: KH
authors.lastname: Simpson
authors.forename: Gabriela
authors.initials: G
authors.lastname: Bowden
authors.forename: Magnus
authors.initials: M
authors.lastname: Höök
authors.forename: Bahman
authors.initials: B
authors.lastname: Anvari
mesh_terms: D000268:Adhesiveness; D001422:Bacterial Adhesion; D005340:Fibrinogen / Q000378:metabolism*; D005353:Fibronectins / Q000378:metabolism*; D055095:Optics and Photonics / Q000295:instrumentation*; D013211:Staphylococcus aureus / Q000502:physiology*
chemical_list: D005353:Fibronectins; D005340:Fibrinogen