title: Bullous pyoderma gangrenosum complicated by disseminated intravascular coagulation with subsequent myelodysplastic syndrome (chronic myelomonocytic leukemia).
abstract: A 33-year-old woman developed a bullous PG precursing a chronic myelomonocytic leukemia (CMML) complicated by life-threatening, disseminated, intravascular coagulation after administration of systemic corticosteroids in combination with immunosuppressant and antibiotic agents. Although the association between PG and leukemia, as well as the coincidence of disseminated intravascular coagulation (DIC) and leukemia, is well known, a premonitoring effect of PG in combination with DIC preceding the diagnosis of chronic myelomonocytic leukemia in the same patient has not been reported recently.
authors.affiliation: Universitätsklinikum Leipzig AöR, Klinik und Poliklinik für Hautkrankheiten, Leipzig, Germany.
authors.forename: Christina
authors.initials: C
authors.lastname: Rogalski
authors.forename: Uwe
authors.initials: U
authors.lastname: Paasch
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Glander
authors.forename: Uwe-Frithjof
authors.initials: UF
authors.lastname: Haustein
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage; D047070:Bandages, Hydrocolloid; D003102:Colloids; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007866:Leg; D015477:Leukemia, Myelomonocytic, Chronic / Q000150:complications*; D011239:Prednisolone / Q000008:administration & dosage; D017511:Pyoderma Gangrenosum / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D003102:Colloids; D011239:Prednisolone; D001379:Azathioprine