Antioxidative effect of citrus essential oil components on human low-density lipoprotein in vitro.
We studied the antioxidative action to evaluate the effect of citrus essential oil components on human LDL in vitro. Among the authentic volatile compounds tested, gamma-terpinene showed the strongest antioxidative effect, and inhibited both the Cu(2+)-induced and AAPH-induced oxidation of LDL. gamma-Terpinene added after 30 min (mid-lag phase) and 60 min (propagation phase) of incubation of LDL with Cu(2+) inhibited LDL oxidation.
Takahashi
Yasuo
Y
Wakayama Agricultural Processing Research Corporation, 398 Tsukatsuki, Momoyama-cho, Naga-gun, Wakayama 649-6112, Japan. wakaken@silver.ocn.ne.jp
Inaba
Nobuya
N
Kuwahara
Shigeru
S
Kuki
Wataru
W
D000578:Amidines / Q000737:chemistry; D000975:Antioxidants; D001713:Biphenyl Compounds; D002957:Citrus / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D000081005:Cyclohexane Monoterpenes; D006801:Humans; D008077:Lipoproteins, LDL / Q000737:chemistry*; D039821:Monoterpenes; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D010851:Picrates / Q000737:chemistry; D013729:Terpenes / Q000494:pharmacology; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry
D000578:Amidines; D000975:Antioxidants; D001713:Biphenyl Compounds; D000081005:Cyclohexane Monoterpenes; D008077:Lipoproteins, LDL; D039821:Monoterpenes; D009822:Oils, Volatile; D010851:Picrates; D013729:Terpenes; D017392:Thiobarbituric Acid Reactive Substances; C018669:gamma-terpinene; C046728:2,2'-azobis(2-amidinopropane); D003300:Copper; C004931:1,1-diphenyl-2-picrylhydrazyl