title: Comparison of neonatal effects of epidural and general anesthesia for cesarean section.
abstract: We assessed the influence of anesthetic technique for cesarean section on neonatal outcome. Thirty parturient women (ASA I/II) were randomly allocated into two groups. In Group GA general anesthesia was induced with 4 mg.kg(-1) thiopental and 1.5 mg.kg(-1) succinylcholine. In group EA epidural anesthesia was performed with 20 ml 0.375% bupivacaine through L(3-4) inter-space. 1-min Apgar scores were significantly higher in group EA (p < 0.001). Neurologic and Adaptive Capacity scores at 2 and 24 h were higher in group EA (p < 0.001). In terms of blood gas values, umbilical arterial pH and pO(2) values were higher in group EA (p < 0.05 and p < 0.001, respectively). The first breast-feeding intervals were found to be shorter in group EA (p < 0.001). We conclude that in terms of better Apgar and NAC scores, acid-base status and earlier initiation of breast-feeding, the epidural anesthesia may be preferred to general anesthesia in cesarean section.
authors.affiliation: Department of Anesthesiology and Reanimation, Ondokuzmayis Universit, and University Faculty of Medicine, Samsun, Turkey. bengimd@hotmail.com
authors.forename: Elif Bengi
authors.initials: EB
authors.lastname: Sener
authors.forename: Fuat
authors.initials: F
authors.lastname: Guldogus
authors.forename: Deniz
authors.initials: D
authors.lastname: Karakaya
authors.forename: Sibel
authors.initials: S
authors.lastname: Baris
authors.forename: Serhat
authors.initials: S
authors.lastname: Kocamanoglu
authors.forename: Ayla
authors.initials: A
authors.lastname: Tur
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000009:adverse effects / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000494:pharmacology; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000494:pharmacology; D001034:Apgar Score; D002045:Bupivacaine / Q000008:administration & dosage / Q000494:pharmacology; D002585:Cesarean Section / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007530:Isoflurane / Q000008:administration & dosage / Q000494:pharmacology; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D013390:Succinylcholine / Q000008:administration & dosage; D013874:Thiopental / Q000008:administration & dosage
chemical_list: D018685:Anesthetics, Inhalation; D000779:Anesthetics, Local; D007530:Isoflurane; D013390:Succinylcholine; D013874:Thiopental; D009609:Nitrous Oxide; D002045:Bupivacaine