title: Granulocytic sarcoma of the pancreas successfully treated with intensive chemotherapy and stem cell transplantation.
abstract: A case of preleukemic granulocytic sarcoma of pancreas is presented. Pancreas is a well described site of secondary metastasis of solid tumors, but occasionally it has been reported as the primary site of leukemia. Like other cases reported in the literature, the present case was initially misdiagnosed as malignant lymphoma. We highlight the importance of an accurate immunohistochemical diagnosis and of an early and intensive acute myeloid leukemia-like treatment for these cases representing an uncommon and aggressive form of acute leukemia.
authors.affiliation: Dipartimento di Biotecnologie Cellulari ed Ematologia, University La Sapienza, Via Benevento 6, Rome, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Breccia
authors.forename: Mariella
authors.initials: M
authors.lastname: D'Andrea
authors.forename: Andrea
authors.initials: A
authors.lastname: Mengarelli
authors.forename: Salvatore G
authors.initials: SG
authors.lastname: Morano
authors.forename: Gianna M
authors.initials: GM
authors.lastname: D'Elia
authors.forename: Giuliana
authors.initials: G
authors.lastname: Alimena
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000628:therapy*; D012074:Remission Induction / Q000379:methods; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000628:therapy*