title: Vestibulo-cerebellar participation in protection of duodenal mucosa: possible role of neurotransmitters.
abstract: Vestibulo cerebellar lesion in rats produced a decrease in the intracellular presecreted mucus together with a decrease in the norepinephrine (NE) and serotonin (5HT) content of the duodenal tissue. Whereas vestibulo cerebellar stimulation by rotation produced an increase in the intracellular presecreted mucus and an increase in the NE content of the duodenal tissue but very little increase in 5HT content of the duodenum. The results suggest that the vestibulo cerebellum by modulating the tissue content of the neurotransmitter NE and 5HT has a direct influence in the protective mechanism through the intracellular mucus content.
authors.affiliation: Neurophysiology Laboratory, Department of Physiology, University of Calcutta, 92 A.P.C. Road, Kolkata 700 009, India.
authors.forename: Debjani
authors.initials: D
authors.lastname: Guha
authors.forename: Sudarshana
authors.initials: S
authors.lastname: Purkayastha
authors.forename: Partha
authors.initials: P
authors.lastname: Chakrabarty
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D004386:Duodenum / Q000502:physiology*; D005260:Female; D007413:Intestinal Mucosa / Q000502:physiology; D008297:Male; D018377:Neurotransmitter Agents / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014722:Vestibule, Labyrinth / Q000502:physiology*
chemical_list: D018377:Neurotransmitter Agents