title: [Clinical experience of gelatin-resorcin-formal (GRF) glue for acute empyema with bronchopleural fistula].
abstract: Gelatin-resorcin-formal (GRF) glue is a new biological adhesive agent with the advantage of sealing efficacy. We report a successful closure of bronchopleural fistula using this agent. A 77-year-old man underwent cavernostomy for lung aspergillosis. After surgery, he developed methicillin-resistant staphylococcus aureus (MRSA)-empyema with bronchopleural fistula. Thoracoplasty and muscular plombage were performed for filling up the cavity and closure of bronchial fistula. But the fistula relapsed 3 days after surgery. GRF glue was injected into the residual cavity, then air-leakage was completely disappeared with tight adhesion of cavity wall. We consider this agent is useful material for the closure of bronchopleural fistula.
authors.affiliation: Department of Thoracic Surgery, Ohta Nishinouchi Hospital, Kohriyama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hasumi
authors.forename: S
authors.initials: S
authors.lastname: Yamanaka
authors.forename: H
authors.initials: H
authors.lastname: Yamanaka
authors.forename: C
authors.initials: C
authors.lastname: Endoh
authors.forename: H
authors.initials: H
authors.lastname: Suda
mesh_terms: D000208:Acute Disease; D000368:Aged; D001228:Aspergillosis / Q000601:surgery; D001983:Bronchial Fistula / Q000601:surgery*; D004338:Drug Combinations; D016724:Empyema, Pleural / Q000601:surgery*; D005557:Formaldehyde; D005780:Gelatin; D006801:Humans; D008172:Lung Diseases, Fungal / Q000601:surgery; D008297:Male; D010995:Pleural Diseases / Q000601:surgery*; D011183:Postoperative Complications / Q000601:surgery*; D012086:Reoperation; D012118:Resorcinols; D016156:Respiratory Tract Fistula / Q000601:surgery*; D013905:Thoracoplasty / Q000379:methods
chemical_list: D004338:Drug Combinations; D012118:Resorcinols; C027813:gelatin-resorcinol-formaldehyde tissue adhesive; D005557:Formaldehyde; D005780:Gelatin