[Acute hemorrhage. View on the problem].
Acute hemorrhage is a main cause of reduction of blood oxygen capacity. The main aim of correction of sequels of acute hemorrhage is to maintain effective gas exchange by restoring central circulation and microcirculation, the rate of diuresis, by normalizing water-salt exchange, to eliminate anemia, hypoproteinemia, and acute blood coagulability disorders. The values of oxygen budget with calculated oxygen delivery and consumption and those of hemoglobin and hematocrit which are of great value only after recovery of circulating blood volume are considered to be major indications for hemotransfusion. A relationship is established between the extraction and uptake of oxygen and its delivery. The concept of the critical level of oxygen delivery is considered, ways of correcting oxygen indebtedness are presented. Alternatives to the use of hemotransfusions by employing the solutions of modified hemoglobulin and perfluorocarbon-containing emulsions are under consideration. A possible algorithm of aid rendering in acute hemorrhage is given.
Moroz
V V
VV
Ostapchenko
D A
DA
Meshcheriakov
G N
GN
Radaev
S M
SM
D000208:Acute Disease; D001784:Blood Gas Analysis; D001802:Blood Substitutes / Q000494:pharmacology; D001803:Blood Transfusion; D006439:Hemodynamics / Q000502:physiology*; D006470:Hemorrhage / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D010100:Oxygen / Q000097:blood*; D010952:Plasma Substitutes / Q000494:pharmacology
D001802:Blood Substitutes; D010952:Plasma Substitutes; D010100:Oxygen