title: Novel antiinsectan oxalicine alkaloids from two undescribed fungicolous Penicillium spp.
abstract: 15-Deoxyoxalicine B (1) and decaturins A (2) and B (3) have been isolated from Penicillium decaturense and Penicillium thiersii, two previously undescribed species obtained as colonists of wood-decay fungi. The structures were determined by 2D NMR experiments and/or single-crystal X-ray diffraction analysis. These compounds are members of a rare structural class, and decaturins A and B feature a new polycyclic ring system. Decaturin B (3) exhibited potent antiinsectan activity against the fall armyworm (Spodoptera frugiperda).
authors.affiliation: Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
authors.forename: Yichao
authors.initials: Y
authors.lastname: Zhang
authors.forename: Chen
authors.initials: C
authors.lastname: Li
authors.forename: Dale C
authors.initials: DC
authors.lastname: Swenson
authors.forename: James B
authors.initials: JB
authors.lastname: Gloer
authors.forename: Donald T
authors.initials: DT
authors.lastname: Wicklow
authors.forename: Patrick F
authors.initials: PF
authors.lastname: Dowd
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D000818:Animals; D018360:Crystallography, X-Ray; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification; D018411:Spodoptera
chemical_list: C474593:15-dexoyoxalicine B; D000470:Alkaloids; D007306:Insecticides; D011753:Pyrones; D013141:Spiro Compounds; C474594:decaturin A; C474595:decaturin B