[The influence of gastroesophageal reflux on asthma].
The association of gastroesophageal reflux (GER) and respiratory symptoms has been investigated for a long time. The results of large number of studies are often conflicting. It seems, however, that with present knowledge an agreement concerning causal relationship between GER and asthma is possible to achieve. This article is to clarify available information related to the subject. It presents current views on pathogenesis of GER, its extra esophageal manifestations, suggested mechanisms linking reflux and respiratory symptoms. We analyzed diagnostic methods used when reflux is suspected as a cause of asthma exacerbations. The treatment recommended in such cases and its efficacy is discussed. Other diseases of the respiratory system connected with GER are also presented.
Bareła
Anna D
AD
Katedry i Kliniki Chorób Wewnetrznych, Pneumonologii i Alergologii, Akademii Medycznej w Warszawie. adbarela@amwaw.edu.pl
Chazan
Ryszarda
R
D001249:Asthma / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D018849:Controlled Clinical Trials as Topic; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans