Tag, you're hit: retroviral insertions identify genes involved in cancer.
Retroviral integrations have been used for many years to identify genes involved in cancer. The recently published mouse genome sequence has allowed large-scale identification of potential human cancer genes and their classification into distinct signaling pathways.
Dudley
Jaquelin P
JP
Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, TX 78705, USA. jdudley@uts.cc.utexas.edu
D000818:Animals; D020077:Endogenous Retroviruses / Q000235:genetics*; D015698:Genomic Library; D006801:Humans; D009052:Leukemia Virus, Murine / Q000235:genetics; D051379:Mice; D016254:Mutagenesis, Insertional / Q000235:genetics*; D009857:Oncogenes / Q000235:genetics*; D011533:Proviruses / Q000235:genetics*