Neuropsychological findings in combat-related posttraumatic stress disorder.
Previous research investigating whether combat-related Posttraumatic Stress Disorder (PTSD) is associated with impaired neuropsychological functioning has yielded inconsistent findings. The present study addressed many methodological limitations of previous research. Neuropsychological measures of intellectual ability, learning, memory, attention, visuospatial ability, executive functioning, language, and psychomotor speed were compared in four groups of early middle-aged community dwelling veterans. The four demographically comparable groups were: (a) those with current PTSD symptoms (n=80); (b) those with a prior history of PTSD but not currently experiencing active PTSD symptoms (n=80); (c) a non-PTSD psychiatrically matched control group (n=80); and (d) a normal control group (n=80). Results indicated that the four groups did not statistically differ on the neuropsychological measures and that veterans with PTSD perform similarly to demographically matched controls. Results further suggested that the cognitive difficulties previously linked to PTSD may actually have been secondary to preexisting individual differences or other clinical conditions coexisting with PTSD.
Crowell
Timothy A
TA
Department of Psychiatry and Behavioral Medicine, University of South Florida, Tampa, FL 33613, USA. TCrowell@hsc.usf.edu
Kieffer
Kevin M
KM
Siders
Craig A
CA
Vanderploeg
Rodney D
RD
D000328:Adult; D001143:Arousal; D001288:Attention; D016022:Case-Control Studies; D003130:Combat Disorders / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D007360:Intelligence; D007858:Learning; D008950:MMPI / Q000706:statistics & numerical data; D008297:Male; D008568:Memory; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance; D011897:Random Allocation; D013313:Stress Disorders, Post-Traumatic / Q000503:physiopathology / Q000523:psychology*; D014481:United States; D014728:Veterans / Q000523:psychology*