title: Cyclosporin A and methotrexate are equally effective in reducing T cell numbers in psoriatic skin lesions but have no consistent effect on IFN-gamma and IL-4 expression in psoriatic skin in situ.
authors.affiliation: Department of Dermatology, Room L3-359, Academic Medical Center, University of Amsterdam, P.O. Box: 22700, The Netherlands. g.piskin@amc.uva.nl
authors.forename: Gamze
authors.initials: G
authors.lastname: Piskin
authors.forename: Vera M R
authors.initials: VM
authors.lastname: Heydendael
authors.forename: Menno A
authors.initials: MA
authors.lastname: de Rie
authors.forename: Jan D
authors.initials: JD
authors.lastname: Bos
authors.forename: Marcel B M
authors.initials: MB
authors.lastname: Teunissen
mesh_terms: D000328:Adult; D000368:Aged; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007371:Interferon-gamma / Q000378:metabolism*; D015847:Interleukin-4 / Q000378:metabolism*; D018655:Lymphocyte Count; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D011446:Prospective Studies; D011565:Psoriasis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D013601:T-Lymphocytes / Q000187:drug effects* / Q000473:pathology
chemical_list: D007166:Immunosuppressive Agents; D015847:Interleukin-4; D007371:Interferon-gamma; D016572:Cyclosporine; D008727:Methotrexate