Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella.
Combined measles, mumps, and rubella (MMR) vaccine did not increase the risk of hospitalisation with invasive bacterial infection in the three months after vaccination; rather there was a protective effect. These results provide no support for the concept of "immunological overload" induced by multiple antigen vaccinations, nor calls for single antigen vaccines.
Miller
E
E
Immunisation Division, Communicable Disease Surveillance Centre, Public Health Laboratory Service, 61 Colindale Avenue, London NW9 5EQ, UK. emiller@phls.org.uk
Andrews
N
N
Waight
P
P
Taylor
B
B
D001424:Bacterial Infections / Q000276:immunology* / Q000517:prevention & control; D002675:Child, Preschool; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000009:adverse effects / Q000276:immunology*; D011018:Pneumonia, Pneumococcal / Q000276:immunology; D012307:Risk Factors
D022542:Measles-Mumps-Rubella Vaccine