title: Clinical usefulness of a new infrared videoendoscope system for diagnosis of early stage gastric cancer.
abstract: BACKGROUND
  Infrared light can penetrate tissue more deeply than visible light. Therefore, an infrared video endoscope may be useful for assessment of gastric submucosal vessels. However, the resolution of currently available infrared video endoscope systems has been unsatisfactory. A new infrared video endoscope system was developed and its clinical utility assessed for diagnosis of early stage gastric cancer.
  
  
  METHODS
  Twenty-five patients with early stage gastric cancer and 8 with gastric adenoma underwent endoscopy with the infrared video endoscope system after intravenous injection of indocyanine green.
  
  
  RESULTS
  Indocyanine green pooling did not appear in adenomas and some intramucosal gastric cancers, whereas it was noted in all submucosally invasive gastric cancers. Tumors not exhibiting indocyanine green pooling were intramucosal, well-differentiated adenocarcinomas of low height (flat-type cancers).
  
  
  CONCLUSIONS
  These results suggest that our new infrared video endoscope provides valuable information about the submucosal aspect of early stage gastric cancer. Infrared video endoscopy may become a powerful technique for determining whether to perform endoscopic mucosal resection.
authors.affiliation: Second Department of Internal Medicine, National Defense, Medical College, Tokorozawa City, Saitama, Japan.
authors.forename: Norikazu
authors.initials: N
authors.lastname: Mataki
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Nagao
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawaguchi
authors.forename: Koji
authors.initials: K
authors.lastname: Matsuzaki
authors.forename: Junichi
authors.initials: J
authors.lastname: Miyazaki
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakajima
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Tsuzuki
authors.forename: Kazurou
authors.initials: K
authors.lastname: Itoh
authors.forename: Hirohumi
authors.initials: H
authors.lastname: Niwa
authors.forename: Soichiro
authors.initials: S
authors.lastname: Miura
mesh_terms: D000236:Adenoma / Q000175:diagnosis*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004867:Equipment Design; D020699:Gastroscopes; D006801:Humans; D007208:Indocyanine Green; D007259:Infrared Rays; D013274:Stomach Neoplasms / Q000175:diagnosis*; D014741:Video Recording
chemical_list: D007208:Indocyanine Green