[The influence of asymptomatic leukocytospermia on interleukin IL-2 and IL-6 levels in male semen plasma].
OBJECTIVE
The study presents the results of the search for a correlation between leukocytospermia and the interleukin IL-2 and IL-6 levels in male semen plasma.


METHODS
Interleukin levels were assessed by immunoenzymatic method (ELISA). Study covered 3 groups of males: I--fertile (No. = 16); II--with leukocytospermia (No = 16); III--with oligoasthenozoospermia (No = 20).


RESULTS
The study revealed higher levels of IL-6 in a group of males with leukocytospermia (10.01 +/- 2.57 pg/ml) and with oligoasthenozoospermia (13.53 +/- 2.78 pg/ml) compared to a group of fertile males (7.68 +/- 1.4 pg/ml) (p < 0.01), however no statistically significant differences in IL-6 levels between group II and III have been observed. Higher level of IL-2 has been noted in III group (16.68 +/- 5.86 pg/ml) compared to I and II group (9.77 +/- 3.18 pg/ml and 6.05 +/- 2.16 pg/ml, respectively) (p < 0.01). No statistically significant difference in IL-2 semen plasma level between the fertile male group and the group with leukocytospermia has been revealed.


CONCLUSIONS
Leukocytospermia is accompanied by an increase in IL-6 semen plasma level whereas IL-2 level remains statistically unchanged.
Swatowski
Dariusz
D
Kliniki Rozrodczości i Andrologii AM w Lublinie.
Jakiel
Grzegorz
G
D000328:Adult; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007248:Infertility, Male / Q000276:immunology* / Q000378:metabolism; D007376:Interleukin-2 / Q000378:metabolism*; D015850:Interleukin-6 / Q000378:metabolism*; D007962:Leukocytes / Q000473:pathology; D007964:Leukocytosis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012661:Semen / Q000276:immunology* / Q000378:metabolism
D007376:Interleukin-2; D015850:Interleukin-6