title: Malignant Sertoli cell tumor in the retained abdominal testis of a unilaterally cryptorchid horse.
abstract: A 13-year-old Morgan gelding was evaluated because of a mass in the caudal region of the abdomen. The horse had been presumed to be a gelding, but necropsy findings revealed a retained testis in the right retroperitoneal space. Histologically, the retained testis contained neoplastic cells; metastases were identified in the liver, spleen, lungs, and sublumbar lymph nodes. Immunohistochemical examination of the testis and metastatic tissues confirmed the diagnosis of malignant Sertoli cell tumor. Testicular neoplasms are infrequently reported in stallions. Seminomas are most commonly reported, whereas Sertoli cell tumors are considered to be rare. Typical biological behavior of Sertoli cell tumors in horses is unknown. To the authors' knowledge, there have been 2 reports of Sertoli cell tumors in horses; the tumors developed in descended testes, and 1 tumor was malignant.
authors.affiliation: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Pratt
authors.forename: Brian A
authors.initials: BA
authors.lastname: Stacy
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Whitcomb
authors.forename: Justin D
authors.initials: JD
authors.lastname: Vidal
authors.forename: Hilde E V
authors.initials: HE
authors.lastname: De Cock
authors.forename: W David
authors.initials: WD
authors.lastname: Wilson
mesh_terms: D000818:Animals; D003456:Cryptorchidism / Q000150:complications / Q000662:veterinary*; D017809:Fatal Outcome; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D008113:Liver Neoplasms / Q000556:secondary / Q000662:veterinary; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary; D008297:Male; D012707:Sertoli Cell Tumor / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D013160:Splenic Neoplasms / Q000556:secondary / Q000662:veterinary; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*