title: Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.
abstract: Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride in pyridine produced adenosine 5'-phosphoramidates in good yields under mild conditions, it is interesting that nucleophilic attack of amino acid methyl esters only occurred on alpha-phosphorus of ADP.
authors.affiliation: Bioorganic Phosphorus Chemistry Lab of Education Ministry, Department of Chemistry, School of Life Sciences and Engineering, Tsinghua University, Beijing 100084, P. R. China. fuhua@mail.tsinghua.edu.cn
authors.forename: Hua
authors.initials: H
authors.lastname: Fu
authors.forename: Bo
authors.initials: B
authors.lastname: Han
authors.forename: Yu-Fen
authors.initials: YF
authors.lastname: Zhao
mesh_terms: D000244:Adenosine Diphosphate / Q000737:chemistry*; D000249:Adenosine Monophosphate / Q000031:analogs & derivatives* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry*; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: D014297:Trimethylsilyl Compounds; C034515:phenylalanine methyl ester; D000249:Adenosine Monophosphate; D010649:Phenylalanine; C015651:adenosine 5'-phosphoramidate; D000244:Adenosine Diphosphate