title: Follow-up of breast lesions detected by MRI not biopsied due to absent enhancement of contrast medium.
abstract: Our objective was to follow-up patients in whom scheduled MR-guided vacuum biopsies for suspicious lesions were aborted due to absent enhancement of contrast medium. Thirty-seven of 291 scheduled MR-guided vacuum biopsies were aborted. Six cases were lost to follow-up. Two could be unequivocally identified and were nevertheless biopsied. In 25 of 29 patients absent enhancement was confirmed on subsequent studies without compression. Varying hormonal or inflammatory changes between initial MRI and MR-guided vacuum biopsy most probably explain the findings. Enhancement re-appeared on short-term follow-up <6 months without compression in 4 of the 29 patients. Too strong compression during MR-guided vacuum biopsy explains the absence of enhancement in these patients. Of note, on histology, three of these cases proved malignant. We conclude that short-term follow-up without compression is necessary and recommended for all lesions not visible during scheduled MR-guided vacuum biopsy.
authors.affiliation: Department of Obstetrics and Gynecology, Martin Luther University Halle-Wittenberg, Magdeburger Strasse 16, 06112 Halle, Germany.
authors.forename: L
authors.initials: L
authors.lastname: Hefler
authors.forename: J
authors.initials: J
authors.lastname: Casselman
authors.forename: B
authors.initials: B
authors.lastname: Amaya
authors.forename: A
authors.initials: A
authors.lastname: Heinig
authors.forename: T
authors.initials: T
authors.lastname: Alberich
authors.forename: H
authors.initials: H
authors.lastname: Koelbl
authors.forename: S H
authors.initials: SH
authors.lastname: Heywang-Köbrunner
mesh_terms: D016477:Artifacts; D001706:Biopsy; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011312:Pressure / Q000009:adverse effects; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted
chemical_list: D003287:Contrast Media