[Comparison of peritoneal transport of solutes and water during CAPD with glucose or amino acids solutions. Preliminary report].
The aim of the study was the comparison of peritoneal transport of solutes and water during dialysis with presently used 1.1% amino acid solution in relation to 1.36% glucose solution. 20 clinically stable patients on CAPD for 50.0 +/- 27.6 months were enrolled into the study. On the basis of blood and dialysate samples taken during 4-hour CAPD, intraperitoneal dialysate volume and diffusive mass transport coefficients (KBD) for: glucose, creatinine, urea, sodium, potassium and total protein were calculated. Intraperitoneal dialysate volume was higher in the case of amino acid solution in comparison to glucose solution. The KBD values for the investigated solutes were higher when amino acid solution was used, but for glucose and sodium the KBD values were statistically significantly higher. In conclusion, the differences in transperitoneal transport of solutes and water between both solutions found in our study suggest better clinical usefulness of amino acid solution than standard glucose solution for achieving adequate ultrafiltration.
Olszowska
Anna
A
Klinika Nefrologii ze Stacja Dializ Centralnego Szpitala Klinicznego WAM w Warszawie.
Waniewski
Jacek
J
Weryński
Andrzej
A
Marciniak
Maria
M
Wańkowicz
Zofia
Z
D000328:Adult; D000368:Aged; D000601:Amino Acids, Essential / Q000008:administration & dosage / Q000378:metabolism*; D001693:Biological Transport, Active; D003404:Creatinine / Q000378:metabolism; D005260:Female; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism*; D015312:Hemodialysis Solutions / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010537:Peritoneum / Q000378:metabolism*; D013997:Time Factors; D014508:Urea / Q000378:metabolism; D014867:Water / Q000378:metabolism
D000601:Amino Acids, Essential; D015312:Hemodialysis Solutions; D014867:Water; D014508:Urea; D003404:Creatinine; D005947:Glucose