Flavonoids from Achillea nobilis L.
The detailed investigation of a methanolic extract of aerial parts of Achillea nobilis resulted in the isolation of 10 flavonoids. A new C-glycosylflavone, luteolin-6-C-apiofuranosyl-(1'''-->2'')-glucoside, was isolated besides orientin, isoorientin, vitexin, isoschaftoside, luteolin-7-O-beta-glucuronide, luteolin-4'-O-beta-glucoside and quercetin-3-O-methyl ether and two rare flavonolglycosides, quercetin-3-O-alpha-arabinosyl-(1'''-->6'')-glucoside and quercetin-3-O-methylether-7-O-beta-glucoside. The structures were established either by comparison with authentic substances or by UV, 1H NMR and 13C NMR spectroscopic methods including 2D-NMR techniques and ESI-MS.
Krenn
Liselotte
L
Institute of Pharmacognosy, University of Vienna, Pharmacy-Center, Althanstrasse 14, A-1090 Vienna, Austria. liselotte.krenn@univie.ac.at
Miron
Anca
A
Pemp
Enne
E
Petr
Ursula
U
Kopp
Brigitte
B
D031162:Achillea / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D019075:Electrophoresis, Capillary; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry; D047311:Luteolin; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D008958:Models, Molecular; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D011794:Quercetin / Q000737:chemistry / Q000302:isolation & purification
D005419:Flavonoids; D010936:Plant Extracts; D011794:Quercetin; D047311:Luteolin; D000432:Methanol