[The expression of nuclear factor kappa B in cancer cells of human adenocarcinoma].
OBJECTIVE
Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis.


METHODS
Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma.


RESULTS
Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus.


CONCLUSIONS
The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer.
Chen
Yao
Y
Department of Anatomy, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Li
Ruixiang
R
D000230:Adenocarcinoma / Q000378:metabolism* / Q000556:secondary; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D016328:NF-kappa B / Q000096:biosynthesis*; D012004:Rectal Neoplasms / Q000378:metabolism* / Q000473:pathology
D016328:NF-kappa B