[Administration of epithalamine in the treatment of unstable glaucoma of different types after normalization of intraocular pressure].
The treatment effect and clinical efficacy of epithalamine solution was studied on 28 patients (42 eyes) with unstable glaucoma and normalized intraocular pressure (IOP). Epithalamine belongs to the group of cytomedines and it has a modeling effect on the functional activity of the simpatico-adrenaline system, adrenal cortex and anti-oxidizing activity. The clinical study showed that the use of epithalamine solution resulted in normalization of the biochemical activity of the neuro-humoral triphism (adrenaline, norepinephrine, and hydrocortisone). It leads to an increased diameter of arterioles of the bulbar conjunctiva and of the optic disk as well as to a decreased degree of congestive angiopathy and of intravascular aggregation of erythrocytes.
Egorov
V V
VV
Sorokin
E L
EL
Smoliakova
G P
GP
D000818:Animals; D002417:Cattle; D004837:Epinephrine / Q000652:urine; D019261:Epithalamus / Q000737:chemistry; D005260:Female; D005901:Glaucoma / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D006706:Homeostasis; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007273:Injections, Intramuscular; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine; D010455:Peptides / Q000008:administration & dosage*; D010870:Pineal Gland / Q000737:chemistry; D013997:Time Factors; D014020:Tissue Extracts / Q000008:administration & dosage; D014794:Visual Fields
D010455:Peptides; D014020:Tissue Extracts; C027437:epithalamin; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine