title: Loniceroside C, an antiinflammatory saponin from Lonicera japonica.
abstract: A new triterpenoid saponin, loniceroside C was isolated from the aerial parts of Lonicera japonica. Its structure was established to be 3-O-beta-D-glucopyranosyl hederagenin 28-O-alpha-L-rhamnopyranosyl (1-->2)-[beta-D-xylopyranosyl(1-->6)]-beta-D-glucopyranosyl ester by spectroscopic techniques and chemical transformations. Loniceroside C showed in vivo antiinflammatory activity against mouse ear edema provoked by croton oil.
authors.affiliation: SK Chemicals Ltd., Suwon, Korea.
authors.forename: Wie Jong
authors.initials: WJ
authors.lastname: Kwak
authors.forename: Chang Kyun
authors.initials: CK
authors.lastname: Han
authors.forename: Hyeun Wook
authors.initials: HW
authors.lastname: Chang
authors.forename: Hyun Pyo
authors.initials: HP
authors.lastname: Kim
authors.forename: Sam Sik
authors.initials: SS
authors.lastname: Kang
authors.forename: Kun Ho
authors.initials: KH
authors.lastname: Son
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use*; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006027:Glycosides; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy; D031239:Lonicera; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D006027:Glycosides; D010936:Plant Extracts; D012503:Saponins; C420335:loniceracetalide A