title: Impaired mirror-image imitation in Asperger and high-functioning autistic subjects.
abstract: Imitation is crucial for proper development of social and communicative skills. Here, we argue that, based on an error analysis of a behavioral imitation task, adult Asperger and high-functioning autistic subjects suffer from an intriguing deficit of imitation: they lack the natural preference for imitation in a mirror-image fashion. The imitation task consisted of a simple movement sequence of putting a pen with the left or right hand into a green or a blue cup using one of two possible grips. The subjects were asked to imitate the experimenter's hand movements either using the crossed hand (e.g., the subject's right hand corresponding to the experimenter's right hand) for imitation or to imitate as if looking in a mirror (e.g., the subject's left hand corresponding to the experimenter's right hand). When people normally view other persons face-to-face, they prefer to imitate as in a mirror, and observation of mirror-image-like movements speeds up performance in nonimitative tasks. However, our autistic subjects, defective in social cognition, did not profit from mirror-image movements of others. These results provide a new insight into the difficulties that autistic subjects face in viewing and understanding actions of others.
authors.affiliation: Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, FIN-02015 HUT, Espoo, Finland. avi@neuro.hut.fi
authors.forename: Sari
authors.initials: S
authors.lastname: Avikainen
authors.forename: Andreas
authors.initials: A
authors.lastname: Wohlschläger
authors.forename: Sasu
authors.initials: S
authors.lastname: Liuhanen
authors.forename: Ritva
authors.initials: R
authors.lastname: Hänninen
authors.forename: Riitta
authors.initials: R
authors.lastname: Hari
mesh_terms: D000328:Adult; D020817:Asperger Syndrome / Q000503:physiopathology*; D001321:Autistic Disorder / Q000503:physiopathology*; D004292:Dominance, Cerebral; D006801:Humans; D007100:Imitative Behavior