title: Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference.
abstract: This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.
authors.affiliation: Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA. paula.haffman@uchsc.edu
authors.forename: Paula L
authors.initials: PL
authors.lastname: Hoffman
authors.forename: Michael
authors.initials: M
authors.lastname: Miles
authors.forename: Howard J
authors.initials: HJ
authors.lastname: Edenberg
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Sommer
authors.forename: Boris
authors.initials: B
authors.lastname: Tabakoff
authors.forename: Jeanne M
authors.initials: JM
authors.lastname: Wehner
authors.forename: Joanne
authors.initials: J
authors.lastname: Lewohl
mesh_terms: D000428:Alcohol Drinking / Q000235:genetics*; D000437:Alcoholism / Q000235:genetics*; D000818:Animals; D001921:Brain / Q000503:physiopathology*; D002755:Choice Behavior / Q000502:physiology*; D004361:Drug Tolerance / Q000235:genetics; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000502:physiology; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D020411:Oligonucleotide Array Sequence Analysis; D011493:Protein Kinase C / Q000235:genetics; D051381:Rats; D012641:Selection, Genetic
chemical_list: C087857:protein kinase C gamma; D011493:Protein Kinase C