Brain imaging: how stable are synaptic connections?
Cortical circuits can undergo experience-dependent remodeling, while retaining the capacity for long-term information storage. The stability of individual synaptic connections is fundamental to both processes, but poorly understood; two studies using new in vivo imaging techniques have finally shed some light on this important issue.
Meyer
M P
MP
Department of Molecular and Cellular Physiology, Beckman Center, Stanford University School of Medicine, Stanford, CA 94305, USA. martinm@stanford.edu
Niell
C M
CM
Smith
S J
SJ
D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D003712:Dendrites; D003952:Diagnostic Imaging; D051379:Mice; D013569:Synapses