title: Seroepidemiological survey of rubella immunity among three populations in Shiraz, Islamic Republic of Iran.
abstract: We used indirect ELISA assay to test 1193 sera for rubella IgG and IgM antibodies in a seroepidemiological survey of three age- and gender-differentiated sample populations in Shiraz: 203 children aged 2-7 years, 255 paired mothers and neonates (cord blood) and 480 women aged 14-70 years. Seropositivity among women aged 14-70 years was 96.2%. No IgM positive case was found among the 255 tested cord blood samples. Seropositivity among the 203 children was 97.0% (much higher than previously reported). This may be due to rubella epidemics, which tend to occur every 6-10 years. The impact of introducing rubella vaccination is discussed.
authors.affiliation: Department of Immunology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: M
authors.initials: M
authors.lastname: Doroudchi
authors.forename: A S
authors.initials: AS
authors.lastname: Dehaghani
authors.forename: K
authors.initials: K
authors.lastname: Emad
authors.forename: A A
authors.initials: AA
authors.lastname: Ghaderi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases / Q000706:statistics & numerical data*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005312:Fetal Blood / Q000737:chemistry* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D011247:Pregnancy / Q000097:blood*; D012409:Rubella / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D012411:Rubella Vaccine; D012412:Rubella virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D014504:Urban Health / Q000706:statistics & numerical data*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012411:Rubella Vaccine