title: Chronic sclerosing sialadenitis (Kuttner's tumor): unusual presentation with bilateral involvement of major and minor salivary glands.
abstract: In 1896 Kuttner reported four cases which he described as induration of the submandibular gland. Histologically, they showed chronic inflammation and fibrosis. Sporadic cases of this entity that have come to be known as Kuttner's tumor or chronic sclerosing sialadenitis of the submandibular gland and have been reported throughout the 20th century. This inflammatory tumor has been under-recognized, and awareness of its importance and probable immunologic background have recently become evident. We report an unusual case of chronic sclerosing sialadenitis, affecting both parotid glands, both submandibular glands, and minor salivary glands of the oral cavity, and explore the immunohistochemical profile of this entity.
authors.affiliation: Arkadi M. Rywlin MD Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Greater Miami, Miami Beach, FL 33140, USA.
authors.forename: Mario
authors.initials: M
authors.lastname: Blanco
authors.forename: Thomas
authors.initials: T
authors.lastname: Mesko
authors.forename: Marco
authors.initials: M
authors.lastname: Cura
authors.forename: Beria
authors.initials: B
authors.lastname: Cabello-Inchausti
mesh_terms: D015703:Antigens, CD / Q000378:metabolism; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D010306:Parotid Gland / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D012469:Salivary Glands / Q000378:metabolism / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000378:metabolism / Q000473:pathology*; D012793:Sialadenitis / Q000378:metabolism / Q000473:pathology*; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D015703:Antigens, CD