title: Neural mechanisms for detecting and remembering novel events.
abstract: The ability to detect and respond to novel events is crucial for survival in a rapidly changing environment. Four decades of neuroscientific research has begun to delineate the neural mechanisms by which the brain detects and responds to novelty. Here, we review this research and suggest how changes in neural processing at the cellular, synaptic and network levels allow us to detect, attend to and subsequently remember the occurrence of a novel event.
authors.affiliation: Center for Neuroscience and Department of Psychology, University of California, Davis, 1544 Newton Ct., Davis, California 95616, USA. cranganath@ucdavis.edu
authors.forename: Charan
authors.initials: C
authors.lastname: Ranganath
authors.forename: Gregor
authors.initials: G
authors.lastname: Rainer
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D006801:Humans; D008568:Memory / Q000502:physiology*; D008959:Models, Neurological; D009473:Neuronal Plasticity / Q000502:physiology*; D011323:Primates; D012377:Rodentia; D013569:Synapses / Q000502:physiology