Direct synthesis of unprotected 4-aryl phenylalanines via the Suzuki reaction under microwave irradiation.
[formula: see text] 4-Aryl phenylalanines were prepared as free amino acids from the Suzuki coupling of 4-borono phenylalanine with aryl halides in high yields within 5-10 min under microwave irradiation.
Gong
Yong
Y
Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Welsh & McKean Roads, Spring House, Pennsylvania 19477-0776, USA. ygong@prdus.jnj.com
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Wei
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