Effect of medium-chain triglycerides on the postprandial triglyceride concentration in healthy men.
This study compared the serum lipid concentrations after a single dose of medium-chain triglycerides (MCT) or long-chain triglycerides (LCT) between individuals grouped according to the body mass index (BMI). Twenty-five males participated as volunteers, the test diet containing 10 g of MCT or LCT. Blood samples were collected up to 6 h after the intake of a test diets. The LCT diet resulted in significantly greater increases in areas under the curves (AUCs) for serum and chylomicron triglyceride in the BMI > or = 23 kg/m2 group than those in the BMI < 23 kg/m2 group. The magnitude of response after intake of the MCT diet by the BMI > or = 23 kg/m2 group was significantly lower than that after the LCT diet. These results suggest that, in subjects with BMI > or = 23 kg/m2, the intake of MCT is preferable to that of LCT for maintaining postprandial triglyceride at a low concentration.
Kasai
Michio
M
Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD., 1 Shinmei-cho, Yokosuka, Kanagawa 239-0832, Japan. m-kasai@nisshin.oilliogroup.com
Maki
Hideaki
H
Nosaka
Naohisa
N
Aoyama
Toshiaki
T
Ooyama
Katsuhiko
K
Uto
Harumi
H
Okazaki
Mitsuko
M
Igarashi
Osamu
O
Kondo
Kazuo
K
D000818:Animals; D001774:Blood Chemical Analysis; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D018592:Cross-Over Studies; D004032:Diet; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology; D004311:Double-Blind Method; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008297:Male; D019518:Postprandial Period / Q000502:physiology*; D051381:Rats; D014280:Triglycerides / Q000378:metabolism* / Q000494:pharmacology*
D004042:Dietary Fats, Unsaturated; D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol