Revisiting ethical guidelines for research with terminal wean and brain-dead participants.
Some research is too risky to be conducted on anyone with a life expectancy of more than a few hours. Yet under some circumstances, the research can still be carried out by using subjects who are either brain dead or are soon to undergo a terminal wean, and who have articulated values that inclusion in the study can honor. So argues a team of ethicists and researchers at M.D. Anderson Cancer Center, where such research was recently undertaken.
Pentz
Rebecca D
RD
Flamm
Anne L
AL
Pasqualini
Renata
R
Logothetis
Christopher J
CJ
Arap
Wadih
W
D001926:Brain Death; D032984:Ethics, Research; D017408:Guidelines as Topic; D006805:Human Experimentation / Q000941:ethics*; D006801:Humans; D019452:Terminally Ill; D009927:Tissue and Organ Procurement / Q000941:ethics; D014481:United States; D015300:Ventilator Weaning