title: [Patient assessment for zanamivir therapy (second report) -- a survey of patients with influenza who were prescribed zanamivir during the 2001/2002 season in Japan].
abstract: Patients diagnosed as influenza who were prescribed zanamivir were surveyed from December 2001 to April 2002 in Japan as the same 2000/2001 influenza season. A total of 751 survey questionnaires were returned. We analyzed the efficacy of zanamivir against 367 patients who were diagnosed as influenza by rapid diagnosed kit and took zanamivir within 48 hours after onset of symptoms. Following the first zanamivir treatment, symptom relief was reported by 24.0% of the patients within 12 hours, 52.6% within 24 hours and 79.6% within 48 hours. The patients reported that the severest influenza symptom was fever, 28.4% of the patients started to feel reduction of fever within 12 hours, 62.2% within 24 hours. All of the 751 patients, 98.8% reported that the Diskhaler could be used as instructed by the doctor or pharmacist and 91.3% found the device easy or very easy to use. These results showed that the effect of zanamivir started very fast and the diskhaer was well accepted. This was the same as the previous results.
authors.affiliation: Nagasaki University and Aino Memorial Hospital.
authors.forename: Keizo
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
authors.forename: Norio
authors.initials: N
authors.lastname: Sugaya
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006146:Guanidines; D006801:Humans; D007223:Infant; D007251:Influenza, Human / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011714:Pyrans; D012794:Sialic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D053243:Zanamivir
chemical_list: D000998:Antiviral Agents; D006146:Guanidines; D011714:Pyrans; D012794:Sialic Acids; D053243:Zanamivir