[Fructosamine, high density lipoproteins and degree of dyslipidemia in patients with vascular complications of diabetes mellitus type I].
The contents of products from lipid peroxidation (LP) and from fructosamine oxidation, associated with high-density lipoproteins (HDLP), were examined in the blood of patients with diabetes mellitus (DM) of type 1. It was established that, as the vascular complications of DM, type 1, (i.e. micro- and macroangiopathies) aggravated, the HDLP level, modified by LP heptanophil products, was growing up in the blood serum. The content of the above category of HDLP-associated lipoperoxides depended directly on a quantity of HDLP-bound fructosamine, and it reached a maximum value at the most pronounced dislipidemic disorders accompanied by clinical signs of arteriosclerosis (macroangiopathies).
Volchegorskiĭ
I A
IA
Kharchenkova
N V
NV
D000293:Adolescent; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000097:blood* / Q000209:etiology; D005260:Female; D019270:Fructosamine / Q000097:blood*; D006031:Glycosylation; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000150:complications; D015227:Lipid Peroxidation; D008075:Lipoproteins, HDL / Q000097:blood* / Q000378:metabolism; D008297:Male
D008075:Lipoproteins, HDL; D019270:Fructosamine