title: New 2'-oxygenated flavonoids from Andrographis affinis.
abstract: Three new 2'-oxygenated flavonoids, (2S)-5,7,2',3',4'-pentamethoxyflavanone (1), 5-hydroxy-7,8,2',5'-tetramethoxyflavone (2), and echioidinin 2'-O-beta-d-(6' '-O-acetyl) glucopyranoside (3), together with four known flavonoids, 7-O-methyldihydrowogonin, 7-O-methylwogonin, skullcapflavone I 2'-methyl ether, and skullcapflavone I, and two diterpenoids, andrograpanin and 14-deoxy-11,12-didehydroandrographolide, were isolated from the whole plant of Andrographis affinis. The structures were elucidated by spectral and chemical studies.
authors.affiliation: Natural Products Division, Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India.
authors.forename: M Vijaya
authors.initials: MV
authors.lastname: Bhaskar Reddy
authors.forename: P Hari
authors.initials: PH
authors.lastname: Kishore
authors.forename: C Venkata
authors.initials: CV
authors.lastname: Rao
authors.forename: D
authors.initials: D
authors.lastname: Gunasekar
authors.forename: Cristelle
authors.initials: C
authors.lastname: Caux
authors.forename: Bernard
authors.initials: B
authors.lastname: Bodo
mesh_terms: D035685:Andrographis / Q000737:chemistry*; D002942:Circular Dichroism; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D044950:Flavanones; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006868:Hydrolysis; D007194:India; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: C475152:5,7,2',3',4'-pentamethoxyflavanone; C475151:5-hydroxy-7,8,2',5'-tetramethoxyflavone; D004224:Diterpenes; D044950:Flavanones; D005419:Flavonoids; D005960:Glucosides