title: High frequency of novel germline mutations in the VHL gene in the heterogeneous population of Brazil.
authors.affiliation: Department of Oncogenetics, Hospital do Câncer A C Camargo, São Paulo, Brazil. jccrocha@ludwig.org.br
authors.forename: J C C
authors.initials: JC
authors.lastname: Rocha
authors.forename: R L A
authors.initials: RL
authors.lastname: Silva
authors.forename: B B
authors.initials: BB
authors.lastname: Mendonça
authors.forename: S
authors.initials: S
authors.lastname: Marui
authors.forename: A J G
authors.initials: AJ
authors.lastname: Simpson
authors.forename: A A
authors.initials: AA
authors.lastname: Camargo
mesh_terms: D001938:Brazil; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004252:DNA Mutational Analysis; D005192:Family Health; D005787:Gene Frequency; D005838:Genotype; D018095:Germ-Line Mutation; D006801:Humans; D008025:Ligases / Q000235:genetics*; D010641:Phenotype; D025521:Tumor Suppressor Proteins; D044767:Ubiquitin-Protein Ligases; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D006623:von Hippel-Lindau Disease / Q000235:genetics* / Q000473:pathology
chemical_list: D025521:Tumor Suppressor Proteins; D004247:DNA; D044767:Ubiquitin-Protein Ligases; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D008025:Ligases; C497446:VHL protein, human