Anticardiolipin antibodies in women with recurrent abortion.
The present study sought to determine whether the level of anticardiolipin antibodies in women with recurrent abortion differed from that in the general population. Enzyme-linked immunosorbent assay was used for detection of anticardiolipin antibodies in a group of 26 patients defined as habitual aborters (at least three consecutive spontaneous abortions), and in a control group of 26 patients each of whom had had at least one live birth without pregnancy wastage. A high level of anticardiolipin antibody activity was detected among 19.23% of the habitual aborters but in none of the controls, indicating an association between anticardiolipin antibody level and habitual abortion.
Daboubi
M K
MK
Department of Obstetrics and Gynaecology, King Hussein Medical Centre, Amman, Jordan.
D000026:Abortion, Habitual / Q000097:blood* / Q000209:etiology*; D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000097:blood*; D016736:Antiphospholipid Syndrome / Q000097:blood* / Q000150:complications*; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D010922:Placenta Diseases / Q000209:etiology; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D012008:Recurrence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013927:Thrombosis / Q000209:etiology
D017153:Antibodies, Anticardiolipin