Antioxidative activity of the blue pigment formed in a D-xylose-glycine reaction system.
A blue compound was prepared from 1 M D-xylose and 0.1 M glycine, and designated Blue-M1, an intermediate color product of melanoidins. As melanoidins are well known to have antioxidative activity as well as high scavenging activity against active oxygen species, the antioxidative activity of Blue-M1 against the peroxidation of linoleic acid was investigated, in addition to the scavenging activity of Blue-M1 toward hydroxyl and DPPH radicals. Blue-M1 suppressed the peroxidation of linoleic acid as effectively as melanoidins did. The scavenging activity of Blue-M1 toward hydroxyl and DPPH radicals was also as strong as that of melanoidins. Blue-M1 showed higher activity with increasing concentration. The pyrrolopyrrole ring and a methine bridge between two pyrrolopyrrole rings in Blue-M1 could be related to the ability for radical scavenging activity, but not four carboxyl groups.
Shizuuchi
Satomi
S
Department of Agricultural Chemistry, Meiji University, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.
Hayase
Fumitaka
F
D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D001713:Biphenyl Compounds; D002084:Butylated Hydroxytoluene / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D016166:Free Radical Scavengers / Q000737:chemistry; D005998:Glycine / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry; D013058:Mass Spectrometry; D010545:Peroxides / Q000737:chemistry; D010851:Picrates / Q000737:chemistry; D010860:Pigments, Biological / Q000494:pharmacology*; D011108:Polymers / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D014810:Vitamin E / Q000737:chemistry; D014994:Xylose / Q000737:chemistry*
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010545:Peroxides; D010851:Picrates; D010860:Pigments, Biological; D011108:Polymers; C011908:melanoidin polymers; D014810:Vitamin E; D002084:Butylated Hydroxytoluene; D017665:Hydroxyl Radical; D014994:Xylose; C004931:1,1-diphenyl-2-picrylhydrazyl; D005998:Glycine