title: [Compression of the spinal cord revealing a seronegative rheumatoid arthritis].
abstract: BACKGROUND
  Craniocervical junction damages may result in a compression of the spinal cord. They may be caused by infectious, tumoral or inflammatory processes. Rheumatoid arthritis is probably among rheumatic diseases the most frequent cause of atlantoaxial arthritis. Nevertheless involvement of the craniocervical junction as the presenting symptom of rheumatoid arthritis is a very rare feature.
  
  
  METHODS
  We report the case of a 61 years old woman who presented with atlantoaxial involvement and spinal cord compression one year before the diagnosis of a seronegative rheumatoid arthritis.
  
  
  CONCLUSIONS
  Symptomatic craniocervical junction damages may appear. Patients with damages of the craniocervical junction and negative investigations should be followed long-term; an underlying inflammatory disease may become evident after significant delay.
authors.affiliation: Service de médecine interne, hôpital Jean-Verdier, Bondy, France.
authors.forename: P
authors.initials: P
authors.lastname: Guilpain
authors.forename: A
authors.initials: A
authors.lastname: Kettaneh
authors.forename: J-M
authors.initials: JM
authors.lastname: Chamouard
authors.forename: J
authors.initials: J
authors.lastname: Stirnemann
authors.forename: M
authors.initials: M
authors.lastname: Thomas
authors.forename: O
authors.initials: O
authors.lastname: Fain
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D012698:Serologic Tests; D013117:Spinal Cord Compression / Q000188:drug therapy*