title: Quantitative measurements of proton spin-lattice (T1) and spin-spin (T2) relaxation times in the mouse brain at 7.0 T.
abstract: The goal of this work is to provide regional T(1) and T(2) values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T(1) in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T(2) measurements were made in the same regions using a single spin echo sequence repeated at six separate echo times. Both T(1) and T(2) measurements were validated with phantom measurements.
authors.affiliation: Nathan S. Kline Institute, Center for Advanced Brain Imaging, Orangeburg, New York 10962, USA.
authors.forename: David N
authors.initials: DN
authors.lastname: Guilfoyle
authors.forename: Victor V
authors.initials: VV
authors.lastname: Dyakin
authors.forename: Jacqueline
authors.initials: J
authors.lastname: O'Shea
authors.forename: Gaby S
authors.initials: GS
authors.lastname: Pell
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Helpern
mesh_terms: D000367:Age Factors; D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D051379:Mice; D008815:Mice, Inbred Strains; D019047:Phantoms, Imaging; D011522:Protons
chemical_list: D011522:Protons