title: A prospective study of the association between smoking and later alcohol drinking in the general population.
abstract: OBJECTIVE
  To address the possible prospective association between smoking habits and risk of later heavy drinking in the adult population.
  
  
  METHODS
  Pooled population-based long-term cohort studies with repeated assessments of smoking and alcohol habits.
  
  
  METHODS
  Copenhagen, Denmark.
  
  
  METHODS
  A total of 14,130 non- to moderate drinkers at baseline, who attended re-examination.
  
  
  METHODS
  Among the non- to moderate drinkers we addressed the relation between smoking habits at first examination and the risk of becoming a heavy and excessive drinker at follow-up.
  
  
  RESULTS
  Level of tobacco consumption at first examination predicted an increased risk of becoming a heavy and excessive drinker in a dose-dependent manner. Men who smoked more than 25 g of tobacco per day had adjusted odds ratios of 2.12 (95% confidence interval (CI): 1.44-3.11) and 3.95 (95% CI: 1.93-8.95) for becoming heavy and excessive drinkers, compared to participants who had never smoked. Equivalent estimates among women were 1.76 (95% CI: 1.02-3.04) and 2.21 (95% CI: 1.00-4.58), respectively.
  
  
  CONCLUSIONS
  This study suggests that tobacco use is associated quantitatively with later risk of heavier drinking.
authors.affiliation: Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: Majken K
authors.initials: MK
authors.lastname: Jensen
authors.forename: Thorkild I A
authors.initials: TI
authors.lastname: Sørensen
authors.forename: Anne T
authors.initials: AT
authors.lastname: Andersen
authors.forename: Thorkil
authors.initials: T
authors.lastname: Thorsen
authors.forename: Janne S
authors.initials: JS
authors.lastname: Tolstrup
authors.forename: Nina S
authors.initials: NS
authors.lastname: Godtfredsen
authors.forename: Morten
authors.initials: M
authors.lastname: Grønbaek
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology; D000437:Alcoholism / Q000453:epidemiology / Q000209:etiology*; D016001:Confidence Intervals; D003718:Denmark / Q000453:epidemiology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology