title: Chemosensory factors influencing alcohol perception, preferences, and consumption.
abstract: This article presents the proceedings of a symposium at the 2002 RSA/ISBRA Meeting in San Francisco, California, co-organized by Julie A. Mennella and Alexander A. Bachmanov of the Monell Chemical Senses Center. The goal of this symposium was to review the role that chemosensory factors (taste, smell, and chemical irritation) play in the perception, preference, and consumption of alcohol. The presented research focused on both humans and laboratory animals and used a variety of approaches including genetic, developmental, pharmacological, behavioral, and psychophysical studies. The presentations were as follows: (1) Introduction and overview of the chemical senses (Julie A. Mennella and Alexander A. Bachmanov); (2) Taste reactivity as a measure of alcohol palatability and its relation to alcohol consumption in rats (Stephen W. Kiefer); (3) Early learning about the sensory properties of alcohol in laboratory animals (Juan Carlos Molina); (4) Early learning about the sensory properties of alcohol in humans (Julie A. Mennella); (5) Genetic dissection of the ethanol-sweet taste relationship in mice (Alexander A. Bachmanov and Michael Tordoff); and (6) Human genetic variation in taste: connections with alcohol sensation and intake (Valerie B. Duffy and Linda M. Bartoshuk). The symposium concluded with a general discussion.
authors.affiliation: Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104-3308, USA. bachmanov@monell.org
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Bachmanov
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Kiefer
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Molina
authors.forename: Michael G
authors.initials: MG
authors.lastname: Tordoff
authors.forename: Valerie B
authors.initials: VB
authors.lastname: Duffy
authors.forename: Linda M
authors.initials: LM
authors.lastname: Bartoshuk
authors.forename: Julie A
authors.initials: JA
authors.lastname: Mennella
mesh_terms: D000428:Alcohol Drinking / Q000235:genetics / Q000503:physiopathology* / Q000523:psychology; D000435:Alcoholic Intoxication / Q000235:genetics / Q000503:physiopathology / Q000523:psychology; D000818:Animals; D001143:Arousal / Q000235:genetics / Q000502:physiology; D001244:Association; D002628:Chemoreceptor Cells / Q000503:physiopathology*; D002755:Choice Behavior / Q000502:physiology; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000235:genetics / Q000503:physiopathology; D005838:Genotype; D006801:Humans; D008297:Male; D051379:Mice; D010641:Phenotype; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012903:Smell / Q000235:genetics / Q000502:physiology*; D013649:Taste / Q000235:genetics / Q000502:physiology*