Treatment of metastatic breast cancer with liver transplantation.
Resection of liver metastases is accepted as an appropriate treatment for colorectal metastases in suitable patients. Liver transplant is not often used for malignant disease as there is a high incidence of undetectable micrometastases elsewhere and recurrence is likely. The effects of immunosuppression may also enhance the growth of malignant cells at other sites. We report a case where a young patient with undiagnosed breast cancer with axillary and liver metastases underwent liver transplantation and is effectively leading a normal life 33 months after transplant.
Wilson
J M
JM
Academic Unit of Surgery, St. James's University Teaching Hospital, Leeds, West Yorkshire, United Kingdom. j.m.wilson@leeds.ac.uk
Carder
P
P
Downey
S
S
Davies
M H
MH
Wyatt
J I
JI
Brennan
T G
TG
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000556:secondary; D018450:Disease Progression; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation; D020360:Neoadjuvant Therapy; D013997:Time Factors