[Sleep and sedation: clinical and electrophysiological parallels].
Clinical and electrophysiological studies were performed in 10 volunteers and 45 patients with Classes I and II, as stated by the American Society of Anesthesiologists, to evaluate consciousness during sedation. Prior studies on volunteers showed that there was a clear correlation between N-REM sleep and SEF in 90% of cases. Based on these findings, the authors propose a modified suppressed consciousness scale whose rating was adjusted to the levels of N-REM sleep. Irrespective of the type and technique of sedation (infusion of thiopental and propofol; PCS, midazolam), changes in the levels of drug-depressed consciousness were found to be the same.
Zaĭtsev
A Iu
AIu
Svetlov
V A
VA
Levin
Ia I
IaI
Oleĭnikov
V V
VV
Kozlov
S P
SP
Nikolaev
A P
AP
D000328:Adult; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D016292:Procedural Sedation / Q000379:methods*; D003243:Consciousness / Q000187:drug effects / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D005283:Fentanyl / Q000494:pharmacology; D006801:Humans; D008297:Male; D008874:Midazolam / Q000494:pharmacology; D015742:Propofol / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects / Q000502:physiology*; D012895:Sleep, REM / Q000187:drug effects* / Q000502:physiology; D013874:Thiopental / Q000494:pharmacology
D018686:Anesthetics, Intravenous; D013874:Thiopental; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol