[Dynamics in microcirculation and regional ventilation of the lung during treatment in patients with destructive tuberculosis].
Studies of the time course of changes in regional blood flow and regional ventilation of the lung in patients with destructive pulmonary tuberculosis (DPT) suggest that there may be different shifts in radionuclide indices after antibacterial therapy. Full recovery of regional blood flow and regional ventilation of the lung sometimes is accounted for by the resolution of inflammatory changes, by the healing of destruction frequently attended by a significant improvement, but there is a more regular change in the areas of the underlying process in particular, through evolving pneumosclerosis. A comprehensive radionuclide study in patients with destructive pulmonary tuberculosis in combination with clinical and X-ray studies allows clinicians to investigate the extent and site of a pathological process and thereby to define the functional status of capillary blood flow and pulmonary alveoles. Radionuclide studies enable a trend of a pathological process in the lung to be defined during treatment since alterations in the lung reflect the time course of changes in a specific process and the efficiency of treatment.
Sigaev
A T
AT
Chukanov
V I
VI
Perfil'ev
A V
AV
Iurgel'
N V
NV
D006801:Humans; D008168:Lung / Q000098:blood supply* / Q000000981:diagnostic imaging; D008833:Microcirculation / Q000000981:diagnostic imaging*; D012123:Pulmonary Ventilation / Q000187:drug effects; D011877:Radionuclide Imaging; D012039:Regional Blood Flow / Q000187:drug effects; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology*