Measurements of the major isoforms of vitamins A and E and carotenoids in the blood of people with spinal-cord injuries.
We used reversed-phase HPLC with diode array detection to simultaneously measure the major isoforms of vitamins A, E, and the carotenoids in serum from 55 healthy people with spinal cord injuries. Typically, the method measured retinol (vitamin A), alpha-tocopherol (vitamin E) and beta-carotene, alpha-carotene, lutein, lycopene, and cryptoxanthin (carotenoids). gamma-Tocopherol (vitamin E), 25-hydroxycalciferol (vitamin D), and the carotenoid zeaxanthin could also be measured when they were present in high concentrations. Healthy people with spinal cord injuries were more likely than similar people without injuries to have low concentrations of alpha-tocopherol, and to a lesser extent retinol and beta-carotene.
Burri
Betty Jane
BJ
Western Human Nutrition Research Center, PWA, Agricultural Research Service, United States Department of Agriculture, 1035 Wickson Hall, 1 Shields Avenue, Davis, CA 95616-8683, USA. bburri@whnrc.usda.gov
Dopler-Nelson
Mindy
M
Neidllinger
Terry Ray
TR
D000328:Adult; D006801:Humans; D007536:Isomerism; D013119:Spinal Cord Injuries / Q000097:blood*; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D014801:Vitamin A; D014810:Vitamin E