title: [Sperm evaluation in testicular cancer patients before and after chemotherapy].
abstract: OBJECTIVE
  Over the last 20 years treatment results of testicular cancer have improved. At present, up to 90% of patients are cured.
  
  
  METHODS
  Semen analysis has been performed in 50 patients before and 3, 6, 12, 12, 18, 24, 30 months after i.t.
  
  
  METHODS
  50 Patients with testicular cancer underwent chemotherapy based on cisplatin. Before and after treatment the semen analysis has been performed on each patients. The results of the patient groups have been compared to healthy group of men.
  
  
  RESULTS
  The quality of the semen is much worse in the group with cancer compared to healthy controls. The deepest impairment of the spermatogenesis has been found 3 mounts after chemotherapy.
  
  
  CONCLUSIONS
  Orchidectomy has no influence on sperm parameters. Semen analysis revealed normospermia in 30% of the patients. 30 months after chemotherapy.
authors.affiliation: Kliniki Nowotworów Układu Moczowego Centrum Onkologii-Instytutu w Warszawie.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Demkow
authors.forename: Ricardo
authors.initials: R
authors.lastname: Faundez
authors.forename: Jacek
authors.initials: J
authors.lastname: Kamoda
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D016022:Case-Control Studies; D002945:Cisplatin / Q000009:adverse effects; D006801:Humans; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D012661:Semen / Q000187:drug effects* / Q000378:metabolism; D013091:Spermatogenesis; D013094:Spermatozoa / Q000187:drug effects* / Q000378:metabolism; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000503:physiopathology*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002945:Cisplatin