title: [Adhesions of the labia minora in three young girls].
abstract: Three girls, 2, 5 and 6 years of age, had labial adhesions: one without complaints but whose mother was anxious about abnormal anatomy of the external genitalia, one with urinary problems because of pooling of the urine in the almost completely covered vagina, relapsing after surgical intervention, and one with irregular adhesions because of sexual abuse. In all three, after (repeated) application of oestrogen cream the adhesions reduced or disappeared. Adhesions of the labia minora can often be noticed under the age of 8 years and dissolve after that age during the period of progressive natural oestrogen production. Therapy consists of application of oestrogen cream on the contact surface of the labia minora. Surgical treatment is disputable and causes a high recurrence, probably higher than conservative treatment.
authors.affiliation: Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Gynaecologie en Verloskunde, Postbus 22.660, 1100 DD Amsterdam. m.a.lubsen@amc.uva.
authors.forename: M A C
authors.initials: MA
authors.lastname: Lubsen-Brandsma
mesh_terms: D000287:Administration, Topical; D002648:Child; D002650:Child Abuse, Sexual; D002675:Child, Preschool; D004967:Estrogens / Q000008:administration & dosage; D005260:Female; D006801:Humans; D000267:Tissue Adhesions / Q000150:complications / Q000209:etiology / Q000628:therapy; D014524:Urethral Obstruction / Q000209:etiology* / Q000628:therapy; D014621:Vagina / Q000473:pathology; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage; D014844:Vulva / Q000473:pathology*; D014845:Vulvar Diseases / Q000150:complications / Q000209:etiology* / Q000628:therapy
chemical_list: D004967:Estrogens; D014622:Vaginal Creams, Foams, and Jellies