Significant variations of responsiveness of rat gut smooth muscles to glutamate.
Our four-year study, conducted on isolated rat stomach and rectum strips from adult rats of the same brood in five series, demonstrated for the first time notable variations of the responsiveness of the gut smooth muscles to glutamate, the findings that point to strong variability of glutamate contractile action which could lead to inconsistencies and should be taken into account in the future research.
Milovanovic
Dragan R
DR
Department of Pharmacology, Medical Faculty, University of Kragujevac, Svetozara Markovica 69, P.O. Box 124, 34000 Kragujevac, Serbia, FR Yugoslavia. piki@ptt.yu
Matovic
Milovan
M
Milicic
Biljana
B
Jankovic
Slobodan M
SM
D000818:Animals; D005260:Female; D018698:Glutamic Acid / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D012007:Rectum / Q000187:drug effects / Q000502:physiology; D013270:Stomach / Q000187:drug effects / Q000502:physiology; D014662:Vasoconstrictor Agents / Q000494:pharmacology*
D014662:Vasoconstrictor Agents; D018698:Glutamic Acid