title: Pathology of sporotrichosis in 10 cats in Rio de Janeiro.
abstract: Ten cats with sporotrichosis were examined clinically and pathologically. They were in very poor general condition, and had widespread ulcerated cutaneous lesions and respiratory signs. Gross internal abnormalities were found only in the lungs and lymph nodes. Histologically, an inflammatory infiltrate and yeast-like structures were observed in the skin, lungs, liver and lymph nodes. The spleen was congested and contained fungal elements. No microscopical changes were observed in the pancreas, kidneys and heart. Sporothix schenckii was isolated from all the skin samples and nasal swabs obtained in vivo, and from all the samples of lung, liver, spleen, lymph nodes, heart and kidney taken postmortem.
authors.affiliation: Serviço de Zoonoses, Instituto de Pesquisa, Clínica Evandro Chagas-Fiocruz, Av Brasil 4365, 21045-900 Rio de Janeiro, RJ, Brasil.
authors.forename: T M Pacheco
authors.initials: TM
authors.lastname: Schubach
authors.forename: A de Oliveira
authors.initials: Ade O
authors.lastname: Schubach
authors.forename: T
authors.initials: T
authors.lastname: Cuzzi-Maya
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
authors.forename: R Santos
authors.initials: RS
authors.lastname: Reis
authors.forename: P C Fialho
authors.initials: PC
authors.lastname: Monteiro
authors.forename: M C
authors.initials: MC
authors.lastname: Gutierrez-Galhardo
authors.forename: B
authors.initials: B
authors.lastname: Wanke
mesh_terms: D000818:Animals; D001938:Brazil; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D002415:Cats; D005260:Female; D017964:Itraconazole / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008297:Male; D011859:Radiography; D013174:Sporotrichosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000662:veterinary*
chemical_list: D017964:Itraconazole