Disseminated Acanthamoeba infection in a human immunodeficiency virus-infected infant.
Infection with Acanthamoeba is difficult to diagnose and treat. We present the first case of disseminated Acanthamoeba infection in an HIV-infected infant. The infant survived 2 years with treatment with several agents having anti-Acanthamoeba activity in vitro.
Schwarzwald
Heidi
H
Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, 77030, USA. hlschwar@texaschildrenshospital.org
Shah
Purvi
P
Hicks
John
J
Levy
Moise
M
Wagner
Milton L
ML
Kline
Mark W
MW
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy*; D000048:Acanthamoeba / Q000302:isolation & purification*; D000562:Amebiasis / Q000175:diagnosis* / Q000188:drug therapy*; D000563:Amebicides / Q000008:administration & dosage*; D000818:Animals; D000900:Anti-Bacterial Agents; D001707:Biopsy, Needle; D018450:Disease Progression; D004359:Drug Therapy, Combination / Q000008:administration & dosage*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D012720:Severity of Illness Index
D000563:Amebicides; D000900:Anti-Bacterial Agents