Traces of human migrations in Helicobacter pylori populations.
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive their gene pools from ancestral populations that arose in Africa, Central Asia, and East Asia. Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade.
Falush
Daniel
D
Department of Molecular Biology, Max-Planck Institut für Infektionsbiologie, 10117 Berlin, Germany.
Wirth
Thierry
T
Linz
Bodo
B
Pritchard
Jonathan K
JK
Stephens
Matthew
M
Kidd
Mark
M
Blaser
Martin J
MJ
Graham
David Y
DY
Vacher
Sylvie
S
Perez-Perez
Guillermo I
GI
Yamaoka
Yoshio
Y
Mégraud
Francis
F
Otto
Kristina
K
Reichard
Ulrike
U
Katzowitsch
Elena
E
Wang
Xiaoyan
X
Achtman
Mark
M
Suerbaum
Sebastian
S
D000349:Africa; D000383:Agriculture; D000569:Americas; D001208:Asia; D001426:Bacterial Proteins / Q000235:genetics; D001499:Bayes Theorem; D004641:Emigration and Immigration; D005006:Ethnicity; D005060:Europe; D005798:Genes, Bacterial; D014644:Genetic Variation; D005828:Genetics, Population; D005843:Geography; D016481:Helicobacter Infections / Q000382:microbiology* / Q000635:transmission; D016480:Helicobacter pylori / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007198:Indians, North American; D007802:Language; D011110:Polymorphism, Genetic; D011114:Polynesia; D044469:Racial Groups; D011995:Recombination, Genetic; D012940:Social Problems; D012984:Software
D001426:Bacterial Proteins; C074689:VacA protein, Helicobacter pylori