title: [Relationship between the heterotopic neurons and intractable epilepsy].
abstract: OBJECTIVE
  To discuss the relationship between heterotopic neurons and intractable epilepsy.
  
  
  METHODS
  Epileptogenic zones were precisely located with MRI, video-EEG monitoring, intracranial electrical recording and electrocorticography monitoring and then resected in seven patients. The removed tissue was processed for conventional pathological examination with immunohistochemical staining.
  
  
  RESULTS
  Heterotopic neurons were found in the white matter of the specimens. All the seven cases experienced a favorable outcome, with six seizure free.
  
  
  CONCLUSIONS
  The heterotopic neurons scattered or clustered in the white matter contribute to the pathogenesis of intractable epilepsy.
authors.affiliation: Department of Functional Neurosurgy, Xuanwu Hospital, The Capital University of Medical Science. Beijing 100053, China. lengyun318@163.net
authors.forename: Tao
authors.initials: T
authors.lastname: Yu
authors.forename: Yuping
authors.initials: Y
authors.lastname: Wang
authors.forename: Guojun
authors.initials: G
authors.lastname: Zhang
authors.forename: Yongjie
authors.initials: Y
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002828:Choristoma / Q000473:pathology*; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009474:Neurons / Q000473:pathology*