Novel and efficient chiral sulfideoxathiane ligands for palladium-catalyzed asymmetric allylic alkylation.
Easily prepared, chiral sulfideoxathiane ligands are described which give excellent enantioselectivity (up to 99% ee) in the Pd-catalyzed allylic alkylation of 1,3-diphenyl-2-propenyl acetate with a range of alkyl malonate nucleophiles.
Okuyama
Yuko
Y
Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan.
Nakano
Hiroto
H
Takahashi
Kouichi
K
Hongo
Hiroshi
H
Kabuto
Chizuko
C