Molecular monitoring of acute myeloid leukemia associated with inv(16): threshold of CBFbeta/MYH11 transcript copy number above which relapse occurs and below which continuous Complete Remission is likely.
Martinelli
G
G
Buonamici
S
S
Visani
G
G
Malagola
M
M
Piccaluga
P P
PP
Isidori
A
A
Bosi
C
C
Bonifazi
F
F
Soverini
S
S
Terragna
C
C
Amabile
M
M
Giannini
B
B
Baccarani
M
M
D000208:Acute Disease; D007446:Chromosome Inversion; D002885:Chromosomes, Human, Pair 16; D018572:Disease-Free Survival; D018628:Gene Dosage; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000235:genetics; D025202:Molecular Diagnostic Techniques; D018365:Neoplasm, Residual / Q000175:diagnosis / Q000235:genetics; D015514:Oncogene Proteins, Fusion / Q000235:genetics; D012334:RNA, Neoplasm / Q000032:analysis; D012008:Recurrence; D012074:Remission Induction; D020133:Reverse Transcriptase Polymerase Chain Reaction
C095514:CBFbeta-MYH11 fusion protein; D015514:Oncogene Proteins, Fusion; D012334:RNA, Neoplasm