Allele frequencies for an interferon-gamma microsatellite in a population of Brazilian leprosy patients.
A group of Brazilian leprosy patients and controls were genotyped for a CA-repeat microsatellite polymorphism within the interferon (IFN)-gamma gene. A significantly higher frequency of alleles 5-7 was observed in this patient population, indicating that IFN-gamma gene polymorphism may contribute to the course of leprosy post-infection.
Reynard
M P
MP
Department of Histocompatability & Immunogenetics, National Blood Dervice, London, UK.
Turner
D
D
Junqueira-Kipnis
A P
AP
Ramos de Souza
M
M
Moreno
C
C
Navarrete
C V
CV
D001938:Brazil; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006801:Humans; D007371:Interferon-gamma / Q000235:genetics*; D007918:Leprosy / Q000235:genetics*; D018895:Microsatellite Repeats; D009010:Monte Carlo Method
D007371:Interferon-gamma