[Gene level diagnosis in malignant lymphoma].
Malignant lymphoma is a diverse group of clonal proliferative disorders derived from immature and mature lymphoid cells. Each subtype of lymphoma is defined according to a combination of morphology, immunophenotype, genetic features and clinical syndromes. Accordingly, based on our practical experience in the laboratory-oncologic point of view, the role, clinical significance, applications and laboratory issues for testing or interpretation of gene level examination in practical oncology of lymphoma are reviewed.
Kamihira
Shimeru
S
Division of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences.
D015321:Gene Rearrangement; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000235:genetics; D025202:Molecular Diagnostic Techniques; D014178:Translocation, Genetic