title: Polytetrafluoroethylene monocusp valve technique for right ventricular outflow tract reconstruction.
abstract: Nonvalve transannular patch repair of right ventricular outflow tract obstructive (RVOTO) defects results in pulmonary insufficiency, which can contribute to early postoperative right ventricular dysfunction. In both animal and clinical studies, monocusp valves provide perioperative RVOT competence and improved right ventricular functional characteristics. In these reports, monocusp leaflet construction with 0.1-mm polytetrafluoroethylene (PTFE) appeared equal, or superior, to biologic monocusp valves. Construction of the polytetrafluoroethylene monocusp valve is an inexpensive and straightforward way to create a competent RVOT in a variety of RVOTO anomalies. Based on our clinical experience, it effectively prevents short-term and significantly reduces midterm pulmonary insufficiency without evidence of stenosis.
authors.affiliation: Department of Surgery, Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. mturren@iupui.edu
authors.forename: Mark W
authors.initials: MW
authors.lastname: Turrentine
authors.forename: Ryan P
authors.initials: RP
authors.lastname: McCarthy
authors.forename: Palaniswamy
authors.initials: P
authors.lastname: Vijay
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Fiore
authors.forename: John W
authors.initials: JW
authors.lastname: Brown
mesh_terms: D000818:Animals; D006350:Heart Valve Prosthesis; D006801:Humans; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants; D011474:Prosthesis Design; D011664:Pulmonary Valve; D014694:Ventricular Outflow Obstruction / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene