[Study of the characteristics of biological membranes used in osteoplasty with the aim of purposeful tissue regeneration on a model of continuous bone marrow cultures].
The biological materials Parodoncol and Hapcol (Polystom Firm) used in osteoplasty were studied in continuous mouse bone marrow cultures. Culturing in continuous bone marrow cultures showed growth and development of stromal and hemopoietic cells on Hapcol and Parodoncol. The materials caused no negative reactions and failed to inhibit bone marrow cell growth. The number of cells gradually increased, hemopoiesis was normal, and young and mature granulocytes formed. This method of culturing proved to be highly effective for evaluation of the characteristics of biological membranes and other composite materials.
Volozhin
A I
AI
Barer
G M
GM
Ianushevich
O O
OO
Chepel'
A A
AA
Lebedev
V G
VG
D000818:Animals; D001854:Bone Marrow Cells / Q000187:drug effects*; D001861:Bone Regeneration / Q000187:drug effects*; D018786:Bone Substitutes / Q000494:pharmacology*; D002478:Cells, Cultured; D003094:Collagen / Q000494:pharmacology*; D004338:Drug Combinations; D017886:Durapatite / Q000494:pharmacology*; D005269:Femur / Q000473:pathology / Q000601:surgery; D006882:Hydroxyapatites / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D023421:Models, Animal
D018786:Bone Substitutes; D004338:Drug Combinations; C104010:Hapcol; D006882:Hydroxyapatites; C475032:Parodoncol; D003094:Collagen; D017886:Durapatite