Concurrent HIV infection and neuroblastoma.
An infant is reported who presented with Pneumocystis carinii pneumonia, secondary to HIV infection, diagnosed at 3 months of age, and who had concurrent paravertebral neuroblastoma. Although neuroblastoma cell lines support the growth of HIV in vitro, this is the first report of a clinical association between HIV infection and neuroblastoma. Although we do not think the conditions are causally linked, we report the case to raise awareness of a possible association between HIV and neuroblastoma. The case also raises the importance of starting antiretroviral treatment with three drugs.
Leotta
N
N
University of Sydney, Department of Oncology, Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Alvaro
F
F
Dalla-Pozza
L
L
Isaacs
D
D
D019380:Anti-HIV Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D003131:Combined Modality Therapy; D018450:Disease Progression; D017809:Fatal Outcome; D015658:HIV Infections / Q000150:complications* / Q000151:congenital / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D013902:Radiography, Thoracic; D012720:Severity of Illness Index; D013904:Thoracic Vertebrae
D019380:Anti-HIV Agents