title: Liposarcoma metastatic to the orbit.
abstract: OBJECTIVE
  To describe a patient with liposarcoma metastatic to the left orbit.
  
  
  METHODS
  A 72-year-old man was admitted with diplopia and proptosis of the left eye. Previously, a retroperitoneal liposarcoma had been surgically removed followed by postoperative radiation. Visual acuity was normal. There was proptosis of the left eye, increased retrobulbar resistance and reduced mobility. Trans-septal orbital biopsies showed liposarcoma. The patient was initially treated with prednisolone and later received radio- and chemotherapy. Despite treatment he lost vision of the left eye and died a few months later.
  
  
  RESULTS
  Histological examination of the orbital tumor revealed a spindle-cell liposarcoma similar to the primary tumor of the retroperitoneum.
  
  
  CONCLUSIONS
  Liposarcoma metastatic to the orbit is rare, but should be suspected in a patient with proptosis caused by a space-occupying lesion and a history of liposarcoma.
authors.affiliation: Eye Pathology Institute, University of Copenhagen, Denmark.
authors.forename: A H Y
authors.initials: AH
authors.lastname: Tehrani
authors.forename: S
authors.initials: S
authors.lastname: Heegaard
authors.forename: J U
authors.initials: JU
authors.lastname: Prause
authors.forename: H C
authors.initials: HC
authors.lastname: Fledelius
authors.forename: S
authors.initials: S
authors.lastname: Daugaard
mesh_terms: D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004172:Diplopia / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D007069:Ifosfamide / Q000627:therapeutic use; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity
chemical_list: D018906:Antineoplastic Agents, Alkylating; D007069:Ifosfamide