New viral fitness test helps determine regimens.
The enigma of failing antiretroviral regimens and rising viral load in patients who are not progressing to AIDS now has an explanation and a tool that will help clinicians determine which patients will experience this phenomenon. It appears at the same time HIV mutates and becomes resistant to antiretrovirals in some patients, the virus also has a reduced ability to replicate. A new replication capacity test can measure whether the virus has developed a reduced ability to replicate.
D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D024882:Drug Resistance, Viral / Q000235:genetics*; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D009154:Mutation
D019380:Anti-HIV Agents