title: Role of bacteria and HLA-B27 in the pathogenesis of reactive arthritis.
abstract: Strictly speaking, "reactive arthritis" is a conventional term with no study-verified definition. This review will focus on the type of arthritis that is induced by the following species: Chlamydia, Shigella, Salmonella, Yersinia, and Campylobacter. The types of arthritis caused by these pathogens share a clinical pattern that is common in the spondyloarthropathies, especially undifferentiated spondyloarthropathy and Reiter's syndrome. All these diseases, including ankylosing spondylitis, must also share major pathogenetic pathways.
authors.affiliation: Division of Rheumatology, University of California at Los Angeles, 35-40 Rehab Center, 1000 Veterans Avenue, Los Angeles, CA 90095, USA. dtyyu@ucla.edu
authors.forename: David
authors.initials: D
authors.lastname: Yu
authors.forename: Jens G
authors.initials: JG
authors.lastname: Kuipers
mesh_terms: D016918:Arthritis, Reactive / Q000150:complications / Q000276:immunology* / Q000382:microbiology* / Q000503:physiopathology; D002169:Campylobacter Infections / Q000150:complications / Q000276:immunology / Q000503:physiopathology; D002450:Cell Communication; D002690:Chlamydia Infections / Q000150:complications / Q000276:immunology* / Q000503:physiopathology; D002692:Chlamydia trachomatis / Q000276:immunology / Q000472:pathogenicity; D004756:Enterobacteriaceae Infections / Q000150:complications / Q000276:immunology / Q000503:physiopathology; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D015796:HLA-B27 Antigen