title: Phased-array MRI of canine prostate using endorectal and endourethral coils.
abstract: A four-channel phased array consisting of one surface coil, two endorectal coils, and one flexible endourethral loop coil was designed for MRI of the canine prostate. The endorectal coils provide high signal in the posterior region of the prostate, while the endourethral and surface coils are sensitive to the central and anterior regions of the prostate. Gel phantom experiments indicate that the proposed phased-array configuration generates 15 times more signal-to-noise ratio (SNR) than a combination of two surface coils and one endorectal coil within the posterior region of the prostate; the performance of the two configurations is comparable near the anterior prostate surface. Ultimate intrinsic SNR (UISNR) analysis was used to compare the proposed phased array's performance to the best possible SNR for external coils. This analysis showed that the proposed phased array outperforms the best-case external coil within the posterior and central regions of the prostate by up to 20 times. In canine experiments in vivo, high-resolution fast spin-echo (FSE) images of the prostate were obtained with a pixel size of 230 microm obtained in 3 min 12 s. The proposed phased-array design potentially can be used to increase the accuracy of prostate cancer staging and the feasibility of MR-guided prostate interventions.
authors.affiliation: Department of Radiology, NMR Research Division, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Yung
authors.forename: Ali Y
authors.initials: AY
authors.lastname: Oner
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Serfaty
authors.forename: Mark
authors.initials: M
authors.lastname: Feneley
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Yang
authors.forename: Ergin
authors.initials: E
authors.lastname: Atalar
mesh_terms: D000818:Animals; D004285:Dogs; D004867:Equipment Design; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods; D008297:Male; D019047:Phantoms, Imaging; D011467:Prostate / Q000033:anatomy & histology*; D011469:Prostatic Diseases / Q000175:diagnosis