Fetal Toxoplasma infection after oocyst inoculation of pregnant rats.
Six groups totalling 53 Wistar rats were fed 10(4)oocysts from one of six different Toxoplasma strains at 15 days of pregnancy. The overall transplacental transmission rate was 51%. This varied between 10% and 80%, dependent on the strain used. The strains of Toxoplasma which are more pathogenic for mice were transmitted transplacentally more frequently than the strains of intermediate or low pathogenicity. There were no statistically significant differences in the rate of congenital transmission of Toxoplasmain rats fed oocysts (present work) or cysts (previous work).
Freyre
A
A
Laboratorio de Toxoplasmosis, Dpto. de Parasitología, Facultad de Veterinaria, Alberto Lasplaces 1550, Montevideo, Uruguay. freyrealvaro@hotmail.com
Falcón
J
J
Mendez
J
J
González
M
M
Venzal
J M
JM
Morgades
D
D
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D005315:Fetal Diseases / Q000469:parasitology*; D005333:Fetus / Q000469:parasitology; D018445:Infectious Disease Transmission, Vertical; D051379:Mice; D033661:Oocysts / Q000254:growth & development; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000469:parasitology*; D051381:Rats; D017208:Rats, Wistar; D014122:Toxoplasma / Q000145:classification / Q000254:growth & development / Q000472:pathogenicity; D014124:Toxoplasmosis, Animal / Q000151:congenital* / Q000469:parasitology / Q000635:transmission*