Smallpox vaccination and the patient with an organ transplant.
Organ transplant recipients are vulnerable to a variety of infections because of the immunosuppressed state required to prevent organ rejection. We review the recommendations of the Centers for Disease Control and Prevention (Atlanta, Georgia) for smallpox vaccination and the possible complications of vaccination in the population with organ transplants. The risk of these complications is presumably dependent on the extent of deficient cell-mediated immunity.
Dropulic
Lesia K
LK
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. lesia@jhmi.edu
Rubin
Robert H
RH
Bartlett
John G
JG
D002487:Centers for Disease Control and Prevention, U.S.; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D018570:Risk Assessment; D012900:Smallpox Vaccine / Q000009:adverse effects* / Q000276:immunology; D019737:Transplants; D014481:United States
D012900:Smallpox Vaccine