title: Prospective cohort study of comprehensive prevention to gastric cancer.
abstract: OBJECTIVE
  To evaluate the preliminary effects of comprehensive prevention of gastric cancer in Zhuanghe County epidemiologically.
  
  
  METHODS
  Stratified sampling and cluster sampling were applied to define the intervention group and the control group. The prospective cohort study was used for evaluating the effect of preventing gastric cancer. The relative risk (RR) and attributable risk percent (AR %) of intervention on gastric cancer death were calculated. Potential years of life lost (PLYY) of the disease was analyzed, and the RR and AR % of PYLL were calculated. Survival analysis was applied among the screened patients.
  
  
  RESULTS
  In the first 4 years after intervening, the relative risk (RR) of intervention on death was 0.5059 (95 % CI: 0.3462-0.7392, P<0.05) with significance statistically. AR % of the intervention on death was 49.41 %. The RR of intervention on cumulative PYLL was 0.6778 (95 % CI: 0.5604-0.8198, P<0.05) with statistic significance. AR % of the intervention on cumulative PYLL was 30.32 %. The four-year survival rate of the screened patients was 0.6751 (95 % CI: 0.5298-0.9047).
  
  
  CONCLUSIONS
  The initiative intervention results showed that the intervention approach used in the trial was effective, it reduced mortality and increased survival rate, and alleviated the adverse effect of gastric cancer on the health and life of screened population.
authors.affiliation: Department of Epidemiology, College of Public Health, China Medical University, Shenyang 110001, Liaoning Province, China. yyuan@mail.cmu.edu.cn
authors.forename: Hai-Qiang
authors.initials: HQ
authors.lastname: Guo
authors.forename: Peng
authors.initials: P
authors.lastname: Guan
authors.forename: Hai-Long
authors.initials: HL
authors.lastname: Shi
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhang
authors.forename: Bao-Sen
authors.initials: BS
authors.lastname: Zhou
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yuan
mesh_terms: D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011315:Preventive Medicine / Q000592:standards; D011446:Prospective Studies; D018570:Risk Assessment; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D016019:Survival Analysis