title: [Mediastinal mature teratoma perforating into the lung with elevated serum carbohydrate antigen 19-9 (CA19-9) levels; report of a case].
abstract: A 17-year-old woman was suddenly seized with anterior chest pain and admitted to our hospital. Chest X-ray, computed tomography (CT) scan and magnetic resonance imaging (MRI) showed a mass shadow in the left middle lung field associated with the left pleural effusion and high serum carbohydrate antigen 19-9 (CA 19-9) levels (58.5 U/ml). We performed a total resection of the tumor with adherent parts of the left lung. The tumor was 6.5 x 3. 8 x 2.9 cm in size, and was made up of soft tissues, fluid and cystic components. The histological diagnosis was a mature cystic teratoma with perforation into the lung, which contained pancreatic tissues, hepatic cells, bronchial epithelium, serous glands and so on. The levels of fluid amylase and CA 19-9 were high. We report mediastinal mature teratoma perforating into the lung and discuss the mechanism of perforation.
authors.affiliation: Department of Surgery, Maebashi Red-Cross Hospital, Maebashi, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Kimura
authors.forename: M
authors.initials: M
authors.lastname: Kamiyoshihara
authors.forename: K
authors.initials: K
authors.lastname: Sakata
authors.forename: H
authors.initials: H
authors.lastname: Itoh
authors.forename: Y
authors.initials: Y
authors.lastname: Morishita
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor / Q000097:blood*; D018395:CA-19-9 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000276:immunology / Q000601:surgery*; D012422:Rupture, Spontaneous; D013724:Teratoma / Q000276:immunology / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen