title: Bacterial adhesion to rigid and foldable posterior chamber intraocular lenses: in vitro study.
abstract: OBJECTIVE
  To determine the in vitro bacterial adherence to intraocular lenses (IOLs) routinely used at 1 center.
  
  
  METHODS
  University Hospital of Vienna, Vienna, Austria.
  
  
  METHODS
  Four types of rigid IOLs (hydrophobic poly[methyl methacrylate] [PMMA] and hydrophilic heparin-surface-modified PMMA) and 5 types of foldable intraocular lenses (hydrophobic silicone, hydrophobic acrylic, and hydrophilic acrylic) were used in the experiment. Under standardized conditions, the IOLs were contaminated with 2 strains of Staphylococcus epidermidis. A sonication method and impression method were used for quantification. The mean bacterial density per lens type (colony forming units/mm(2)) was compared.
  
  
  RESULTS
  With both germs and both quantification methods, more bacteria was found on hydrophobic lenses than on IOLs with hydrophilic surfaces (P =.001). The Alcon AcrySof and Askin UV80F IOLs had the greatest and the Corneal Acrygel and Bausch & Lomb Hydroview IOLs the least affinity to these microorganisms.
  
  
  CONCLUSIONS
  The data suggest that hydrophilic IOLs can help reduce the rate of postoperative endophthalmitis as a result of their surface properties.
authors.affiliation: Department of Ophthalmology, University Hospital of Vienna, Austria. joerg.schauersberger@akh-wien.ac.at
authors.forename: Jörg
authors.initials: J
authors.lastname: Schauersberger
authors.forename: Michael
authors.initials: M
authors.lastname: Amon
authors.forename: Doris
authors.initials: D
authors.lastname: Aichinger
authors.forename: Apostoulos
authors.initials: A
authors.lastname: Georgopoulos
mesh_terms: D000180:Acrylic Resins; D001422:Bacterial Adhesion; D020099:Coated Materials, Biocompatible; D015169:Colony Count, Microbial; D066298:In Vitro Techniques; D007910:Lenses, Intraocular / Q000382:microbiology*; D019904:Polymethyl Methacrylate; D012826:Silicone Elastomers; D013212:Staphylococcus epidermidis / Q000502:physiology*
chemical_list: D000180:Acrylic Resins; D020099:Coated Materials, Biocompatible; D012826:Silicone Elastomers; D019904:Polymethyl Methacrylate