Verification of the selectivity of (+)N-3-benzylnirvanol as a CYP2C19 inhibitor.
Walsky
Robert L
RL
Obach
R Scott
RS
D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D065731:Cytochrome P-450 CYP2C19; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D008617:Mephenytoin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013237:Stereoisomerism
D004791:Enzyme Inhibitors; C454675:N-3-benzylnirvanol; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D008617:Mephenytoin