Evaluation of acrosome reactivity using the Acrobeads test in varicocele patients: findings before and after treatment.
The Acrobeads test was performed on semen samples from 43 patients with varicocele before and after varicocelectomy. Sperm motility significantly increased after surgery (p <.05), while sperm concentration and motile sperm concentration did not alter postoperatively. Sperm motion analysis using CellSoft 3000 did not demonstrate a significant change after treatment. Acrobeads score significantly increased after the procedure (p<.005). Pregnancy was achieved in 10 patients (28%). Acrobeads score in cases that achieved pregnancy was increased postoperatively (p<.005). The percentage of patients with a postoperative increase in Acrobeads score in the group that achieved pregnancy was significantly higher than that observed in the unsuccessful group (p <.05). Sperm parameters other than the Acrobeads score did not show a significant difference between the successful and unsuccessful patients. The Acrobeads test assessed postoperatively can be useful in precisely evaluating fertility potential after varicocele repair.
Fuse
H
H
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan. fuse@ms.toyama-mpu.ac.jp
Iwasaki
M
M
Mizuno
I
I
Ikehara-Kawauchi
Y
Y
D020101:Acrosome Reaction; D000328:Adult; D000818:Animals; D005260:Female; D005298:Fertility; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D013081:Sperm Motility; D014646:Varicocele / Q000503:physiopathology* / Q000601:surgery