[Clinical risk factors for postoperative proliferative vitreoretinopathy (PVR). A prospective study].
OBJECTIVE
To identify clinical risk factors for development of postoperative PVR, to determine the incidence of this complication and its time of onset by a prospective multicentric study.


METHODS
A multicentric and prospective study of 223 patients with rhegmatogenous retinal detachment (RD) was conducted. Logistic regression analysis was used to identify risk factors for PVR among 83 variables related to preoperative, intraoperative and postoperative characteristics.


RESULTS
22 out of 223 RD developed PVR (incidence 9.9%, confidence interval 95%: 5.9-13.9). After logistic regression analysis, four variables showed an odds ratio higher than 1.0 (RD affecting 4 quadrants, cryopexy, aphakia/pseudophakia and those RD in which an encircling band was implanted). None of these factors showed a <<p>> value lower than 0.05. Most of postoperative PVR (77.2%) appeared in the first month after surgery.


CONCLUSIONS
This study establishes the incidence of PVR, and its time of onset, but it was not effective to identify clinical risk factors with a high level of confidence.
Rodríguez de la Rúa
E
E
Instituto Universitario de Oftalmobiología Aplicada, Grupo de Retina, Universidad de Valladolid, Valladolid, Spain. quique@ioba.med.uva.es
Martínez
V
V
Aragón
J
J
Sanabria
R M
RM
Giraldo
A
A
Mayo
A
A
Pastor
J C
JC
Miranda
I
I
García Arumí
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D012163:Retinal Detachment / Q000601:surgery*; D012307:Risk Factors; D018630:Vitreoretinopathy, Proliferative / Q000453:epidemiology*