Magnesium deficit and sudden infant death syndrome (SIDS): SIDS due to magnesium deficiency and SIDS due to various forms of magnesium depletion: possible importance of the chronopathological form.
Sudden Infant Death Syndrome (SIDS) might be due to the fetal consequences of a Mg maternal deficiency, which might be prevented by simple atoxic nutritional Mg intake by the mother. Various stresses in the pregnant women or in the infant may transform a simple Mg deficiency into Mg depletion which may not be cured by nutritional Mg supplement, but requires a correction of its causal dysregulation. Beside the well established risk factors in baby care and in the environment, it is important to stress the possible role of a primary hypofunction of the biological clock. This may be treated by darkness therapy: total light deprivation at night for the infant and atoxic nutritional Mg supplement for the pregnant women. The place in the prevention of SIDS of Mg therapy for the infant and of the use of melatonin, L-tryptophan and taurine is now uncertain yet.
Durlach
Jean
J
SDRM, Université P et M. Curie, Paris VI, Bât. A-6ème étage, 4 Place Jussieu, F-75252 Paris Cedex, France. Jean.Durlach@wanadoo.fr
Pagès
Nicole
N
Bac
Pierre
P
Bara
Michel
M
Guiet-Bara
Andrée
A
D000328:Adult; D001683:Biological Clocks / Q000502:physiology*; D001833:Body Temperature Regulation / Q000502:physiology; D004777:Environment; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008275:Magnesium Deficiency / Q000150:complications* / Q000503:physiopathology; D011247:Pregnancy; D013312:Stress, Physiological / Q000378:metabolism / Q000503:physiopathology; D013398:Sudden Infant Death / Q000209:etiology*