title: Metastatic melanoma presenting as cardiac mass and hemobilia.
abstract: We present a rare case of malignant melanoma of unknown primary origin presenting as cardiac and cholecystic masses. In this 72-year-old man, a cardiac lesion caused right ventricular outlet obstruction, and gallbladder lesions led to hemobilia. Right atrial and gallbladder metastases were resected. After 2 years of disease-free survival, the patient had recurrent skin lesions, which were treated with local resection and dacarbazine. The patient has survived for more than 5 years after initial diagnosis, with continued complete clinical remission. This case illustrates the importance of aggressive surgical resection and chemotherapy in the treatment of metastatic malignant melanoma.
authors.affiliation: Divisions of Medical Oncology, Mayo Clinic Rochester, MN 55905, USA.
authors.forename: Guangzhi
authors.initials: G
authors.lastname: Qu
authors.forename: Judith S
authors.initials: JS
authors.lastname: Kaur
authors.forename: James B
authors.initials: JB
authors.lastname: Seward
mesh_terms: D000368:Aged; D005706:Gallbladder Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D006338:Heart Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D006431:Hemobilia; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D012074:Remission Induction; D014463:Ultrasonography