Capacitance and resistance of the bilayer lipid membrane formed of phosphatidylcholine and cholesterol.
Capacity and electric resistance of lipid membranes composed of lecithin and cholesterol were determined. The components were chosen for the study because they were present in biological membranes. Capacitance of the lecithin and cholesterol membranes amounts to 0.38 and 0.61 microF/cm(2), and resistance to 1.44(10(4)and 2.12(10(6)Omega cm(2), respectively. A 1:1 complex appears as a result of lecithin-cholesterol membrane formation. Parameters of the membrane formed of the lecithin-cholesterol complex were determined: surface concentration (Gamma(3)), capacitance (C(3)), and conductance (R;(3)(-1), as well as the stability constant (K) of the complex. The mean values of those magnitudes are as follows: 4.265(10(-6)mol/m(2), 0.54 microF/cm(2), 1.381(10(-6)Omega(-1)cm(-2)and 3.748(10(7), respectively.
Naumowicz
Monika
M
Institute of Chemistry, University of Białystok, al. J. Piłsudskiego 11/4, Poland.
Petelska
Aneta D
AD
Figaszewski
Zbigniew A
ZA
D002784:Cholesterol / Q000737:chemistry*; D025802:Electric Capacitance; D017097:Electric Impedance; D004563:Electrochemistry; D066298:In Vitro Techniques; D008051:Lipid Bilayers / Q000737:chemistry*; D008956:Models, Chemical; D010713:Phosphatidylcholines / Q000737:chemistry*
D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D002784:Cholesterol