Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi.
Ganodermadiol, lucidadiol and applanoxidic acid G were isolated as first triterpenes from the European Basidiomycete Ganoderma pfeifferi. The compounds show antiviral activity against influenza virus type A and HSV type 1.
Mothana
R A A
RA
Department of Pharmaceutical Biology, Ernst-Moritz-Arndt University Greifswald, Greifswald D-17487, Germany.
Awadh Ali
N A
NA
Jansen
R
R
Wegner
U
U
Mentel
R
R
Lindequist
U
U
D000998:Antiviral Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D032902:Ganoderma; D006801:Humans; D009980:Influenza A virus / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D014315:Triterpenes / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
D000998:Antiviral Agents; D010936:Plant Extracts; D014315:Triterpenes