Breast cancer cell lines: friend or foe?
The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.
Burdall
Sarah E
SE
Molecular Medicine Unit, University of Leeds, Leeds, UK.
Hanby
Andrew M
AM
Lansdown
Mark R J
MR
Speirs
Valerie
V
D001943:Breast Neoplasms / Q000473:pathology*; D018929:Cell Culture Techniques / Q000379:methods / Q000592:standards*; D006801:Humans; D011786:Quality Control; D014407:Tumor Cells, Cultured