Understanding cancer through proteomics.
Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies such as two-dimensional gel electrophoresis and mass spectrometry, complement genomic technologies, providing cancer researchers with powerful tools for cancer diagnosis and prognosis and for the identification of targets for therapy.
Choi
Woonyoung
W
Department of Pathology, The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
Song
Sonya W
SW
Zhang
Wei
W
D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D007834:Lasers; D013058:Mass Spectrometry; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000378:metabolism; D011379:Prognosis; D040081:Protein Array Analysis; D011485:Protein Binding; D020543:Proteome
D020543:Proteome