title: Bacterial siderophores: synthesis and biological activities of novel pyochelin analogues.
abstract: The synthesis and biological activities of four pyochelin analogues substituted in different parts of the molecule are reported: 5-NHBoc-pyochelin, 3"N-Boc-pyochelin, 3"-nor-NH-pyochelin and neopyochelin II, the enantiomer of natural pyochelin. All these compounds complex iron(III) and transport it at different rates into the cells of Pseudomonas aeruginosa.
authors.affiliation: Laboratorium Kimia Organik FMIPA-UNRI, Jl Raya Bangkinang Km 12.5, Pekanbaru 28293, Indonesia.
authors.forename: A
authors.initials: A
authors.lastname: Zamri
authors.forename: I J
authors.initials: IJ
authors.lastname: Schalk
authors.forename: F
authors.initials: F
authors.lastname: Pattus
authors.forename: M A
authors.initials: MA
authors.lastname: Abdallah
mesh_terms: D007202:Indicators and Reagents; D007501:Iron / Q000378:metabolism; D007502:Iron Chelating Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000138:chemical synthesis* / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000737:chemistry* / Q000187:drug effects / Q000378:metabolism; D017262:Siderophores / Q000138:chemical synthesis* / Q000494:pharmacology*; D013844:Thiazoles
chemical_list: D007202:Indicators and Reagents; D007502:Iron Chelating Agents; D010636:Phenols; D017262:Siderophores; D013844:Thiazoles; C025316:pyochelin; D007501:Iron