title: Histopathological characteristics of eruption mesenchymal calcified hamartoma: two case reports.
abstract: Odontogenic calcified masses were present in the opercula of lower first molars that were delayed in eruption. The masses were relatively small, opaque, white in color with a smooth texture. Histopathological examinations revealed that they contained osteodentin, cementum, and pulp-like components; however, not odontogenic epithelial cells or enameloid. Further, mesenchymal multinucleated giant cells and dysplastic dental matrices were observed in the connective tissues surrounding the masses. These clinical and histopathological findings disagree with the features of pericoronal odontogenic hamartoma lesions, including odontoma, ameloblastic fibroma, and ameloblastic fibro-odontoma. Therefore, we propose to categorize this odontogenic mass as a new variety of hamartoma, eruption mesenchymal calcified hamartoma.
authors.affiliation: Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamada-oka, Suita, Osaka 565-0871, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Onishi
authors.forename: Suguru
authors.initials: S
authors.lastname: Sakashita
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ogawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Ooshima
mesh_terms: D002114:Calcinosis / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003238:Connective Tissue / Q000473:pathology; D003739:Dental Cementum / Q000473:pathology; D003743:Dental Enamel / Q000002:abnormalities; D003782:Dental Pulp / Q000473:pathology; D003804:Dentin / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D015726:Giant Cells / Q000473:pathology; D005882:Gingival Diseases / Q000473:pathology*; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D008648:Mesoderm / Q000473:pathology*; D008963:Molar; D014078:Tooth Eruption