E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.
Love-Gregory
L
L
Wasson
J
J
Lin
J
J
Skolnick
G
G
Suarez
B
B
Permutt
M A
MA
D000255:Adenosine Triphosphate / Q000502:physiology; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide; D024661:Potassium Channels, Inwardly Rectifying / Q000235:genetics* / Q000378:metabolism; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics; D044465:White People / Q000235:genetics*
D024661:Potassium Channels, Inwardly Rectifying; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D000255:Adenosine Triphosphate