Nature of haem-haem interaction.
Haem-haem interaction consists of a change of tension at the haems, caused by a transition between two alternative quaternary structures of the protein. Dr Perutz describes how spin changes that accompany reaction with ligands alter the oxygen affinity of the haems.
Perutz
M F
MF
MRC Laboratory of Molecular Biology, Hills Road, Cambridge.
D000494:Allosteric Regulation; D000495:Allosteric Site; D018360:Crystallography, X-Ray; D006418:Heme / Q000737:chemistry* / Q000378:metabolism*; D006454:Hemoglobins / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000737:chemistry / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D020836:Protein Structure, Quaternary; D019265:Spectroscopy, Near-Infrared; D055672:Static Electricity; D013816:Thermodynamics
D006454:Hemoglobins; D006418:Heme; D007501:Iron; D010100:Oxygen