Purely follicular mycosis fungoides without mucinosis: report of two cases with review of the literature.
Follicular lesions can either associate with typical patch-/plaque-type mycosis fungoides or, more rarely, be the only clinical manifestation of the disease. We describe 2 adult patients who presented with alopecia and disseminated follicular erythematous papules, and comedones and cysts, respectively. In both patients, histology showed a folliculotropic infiltrate of atypical lymphocytes that spared the epidermis, in the absence of follicular mucinosis. Molecular genetic analysis confirmed the oligo/monoclonal nature of the T-cell infiltrate. Reported cases of purely follicular mycosis fungoides without mucinosis are reviewed.
Monopoli
Alessandro
A
Istituto Dermopatico dell'Immacolata, Istituto di ricovero e cura e carattere scientifico, Rome, Italy.
Annessi
Giorgio
G
Lombardo
Giuseppe A
GA
Baliva
Giannandrea
G
Girolomoni
Giampiero
G
D000368:Aged; D001707:Biopsy, Needle; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D000507:Mucinosis, Follicular / Q000473:pathology*; D009182:Mycosis Fungoides / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D011379:Prognosis; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*