title: [In vitro sensitivity of methicillin-resistant Staphylococcus aureus to fusidic acid and trimethoprim-sulfamethoxazole].
abstract: In this study, a total of 225 methicillin resistant Staphylococcus aureus strains isolated from various clinical specimens (114 wounds, 27 blood, 16 of each catheter and sputum, 14 throat swabs, 10 tracheal aspirates, 7 of each urine and drain materials, 6 pleural fluids, 5 graft materials, 2 cerebrospinal fluids, 1 ascitis fluid) of hospitalized patients, were tested in-vitro for their susceptibilities to fusidic acid and trimethoprim-sulfamethoxazole (TMP-SMX) by disk diffusion method. Two-hundred-eighteen (96.9%) of isolates were found susceptible to both fusidic acid and TMP-SMX, 4 (1.8%) were resistant to both of the agents (3 isolates from wound, 1 from sputum), 2 (0.9%) (both of them were wound isolates) were resistant only to fusidic acid, and 1 (0.4%) (throat isolate) was resistant only to TMP-SMX.
authors.affiliation: Ankara Universitesi Tip Fakültesi, Infeksiyon Hastaliklari ve Klinik Bakteriyoloji Anabilim Dali, Ankara.
authors.forename: K Osman
authors.initials: KO
authors.lastname: Memikoğlu
authors.forename: Banu
authors.initials: B
authors.lastname: Bayar
authors.forename: Ozlem
authors.initials: O
authors.lastname: Kurt
authors.forename: Fügen
authors.initials: F
authors.lastname: Cokça
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D005672:Fusidic Acid / Q000494:pharmacology*; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D005672:Fusidic Acid; D015662:Trimethoprim, Sulfamethoxazole Drug Combination