title: Further constituents from Caralluma negevensis.
abstract: Two new megastigmane glycosides (1 and 2) and two new flavone glycosides (3 and 4) were isolated from the methanol extract of the whole plant of Caralluma negevensis Zohary (Asclepiadaceae). The structures of the isolated compounds were characterized as (9R)-2beta,9-dihydroxymegastigma-4,7-dien-3-one-9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (1), 2beta,9-dihydroxymegastigma-4-en-3-one 9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (2), luteolin 3'-O-beta-D-glucopyranoside-4'-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside (3), and luteolin 3',4'-di-O-beta-D-glucopyranoside (4). The structures of the isolated compounds were established on the basis of spectral evidence and chemical transformation.
authors.affiliation: Faculty of Pharmacy, Al-Zaytoonah University of Jordan, PO Box 130, 11733 Amman, Jordan.
authors.forename: Ammar
authors.initials: A
authors.lastname: Bader
authors.forename: Alessandra
authors.initials: A
authors.lastname: Braca
authors.forename: Nunziatina
authors.initials: N
authors.lastname: De Tommasi
authors.forename: Ivano
authors.initials: I
authors.lastname: Morelli
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D002236:Carbohydrate Conformation; D005591:Chemical Fractionation; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002855:Chromatography, Thin Layer; D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D045792:Norisoprenoids; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D003512:Cyclohexanones; D005419:Flavonoids; D005960:Glucosides; D006027:Glycosides; D045792:Norisoprenoids; C413264:megastigmane