Mastopathy and diabetes.
Sclerosing lymphocytic lobulitis or "diabetic mastopathy" is strongly associated with type 1 diabetes but may occur occasionally in its absence. It is characterized by keloid-type fibrosis, lymphocytic lobulitis, and perivasculitis and epithelioid cells. Infiltrating cells are predominantly B lymphocytes. It may be associated with retinopathy and neuropathy, but more research is needed to verify this association. The etiopathogenesis is unknown and the disorder does not seem to predispose to breast carcinoma or lymphoma.
Kudva
Yogish C
YC
Division of Endocrinology and Metabolism, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA. kudva.yogish@mayo.edu
Reynolds
Carol A
CA
O'Brien
Timothy
T
Crotty
Thomas B
TB
D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D001706:Biopsy; D001940:Breast / Q000473:pathology; D048909:Diabetes Complications; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications; D003930:Diabetic Retinopathy / Q000150:complications; D005260:Female; D005348:Fibrocystic Breast Disease; D005355:Fibrosis; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008413:Mastitis / Q000209:etiology* / Q000473:pathology; D012598:Sclerosis; D013967:Thyroiditis, Autoimmune / Q000150:complications