Early and definitive diagnosis of toxic shock syndrome by detection of marked expansion of T-cell-receptor VBeta2-positive T cells.
We describe two cases of early toxic shock syndrome, caused by the superantigen produced from methicillin-resistant Staphylococcus aureus and diagnosed on the basis of an expansion of T-cell-receptor VBeta2-positive T cells. One case-patient showed atypical symptoms. Our results indicate that diagnostic systems incorporating laboratory techniques are essential for rapid, definitive diagnosis of toxic shock syndrome.
Matsuda
Yoshio
Y
Department of Obstetrics and Gynecology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan. ymatsuda@obgy.twmu.ac.jp
Kato
Hidehito
H
Yamada
Ritsuko
R
Okano
Hiroya
H
Ohta
Hiroaki
H
Imanishi
Ken'ichi
K
Kikuchi
Ken
K
Totsuka
Kyouichi
K
Uchiyama
Takehiko
T
D000328:Adult; D001427:Bacterial Toxins; D004768:Enterotoxins / Q000097:blood*; D005260:Female; D006801:Humans; D011645:Puerperal Infection / Q000175:diagnosis* / Q000382:microbiology; D012772:Shock, Septic / Q000175:diagnosis*; D018089:Superantigens
D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal