[Inherited renal and vascular diseases].
The advances in molecular biology during the last decade have revealed the genes responsible for inherited renal and vascular diseases and their mutations. These genes code structure proteins, receptors, channels, transporters, and signal proteins, which are specifically expressed in the renal and vascular systems. Other genes code modulators of the system. These findings have provided the understanding of molecular mechanisms of hereditary disorders and may open the way for genetic diagnosis of inherited renal and vascular diseases in the field of laboratory medicine.
Shoji
Masaru
M
Department of Laboratory Medicine, Hirosaki University School of Medicine.
Yasujima
Minoru
M
D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis* / Q000235:genetics*; D025202:Molecular Diagnostic Techniques; D009154:Mutation; D014652:Vascular Diseases / Q000175:diagnosis* / Q000235:genetics*