title: Treatment of monomorphic B-cell lymphoma with rituximab after liver transplantation in a child.
abstract: Rituximab, a monoclonal antibody directed against the B-cell specific CD20 antigen has been used with success in post-transplant lymphoproliferative disorder (PTLD) of B-cell phenotype. However, the use of such drug in children with liver transplantation and PTLD is very limited. We report a 2-yr-old liver transplant recipient with monomorphic non-Hodgkin lymphoma of B-cell origin. The lymphoma did not respond to immunosuppression withdrawal, with a subsequent allograft rejection. Despite resumption of immunosuppression and rejection treatment, the lymphoma was successfully treated with rituximab.
authors.affiliation: Department of Pediatric Surgery, Complejo Hospitalario Universitario Juan Canalejo, As Xubias 84, 15006 A Coruña, Spain. jbueno@canalejo.org
authors.forename: Javier
authors.initials: J
authors.lastname: Bueno
authors.forename: Carmen
authors.initials: C
authors.lastname: Ramil
authors.forename: Ivan
authors.initials: I
authors.lastname: Somoza
authors.forename: Amelia
authors.initials: A
authors.lastname: Sanchez-Galindo
authors.forename: Alfonso
authors.initials: A
authors.lastname: Solar
authors.forename: Francisco
authors.initials: F
authors.lastname: Arnal
authors.forename: Augusto
authors.initials: A
authors.lastname: Alvarez
authors.forename: Pilar
authors.initials: P
authors.lastname: Sánchez-Mozo
authors.forename: Manuel
authors.initials: M
authors.lastname: Gómez
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D058846:Antibodies, Monoclonal, Murine-Derived; D005260:Female; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D016393:Lymphoma, B-Cell / Q000188:drug therapy*; D000069283:Rituximab
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab