title: Pulmonary-to-systemic blood flow ratio oriented management after repair of obstructive total anomalous pulmonary venous connection in neonates with single ventricle.
abstract: Caval oxygen saturation was monitored to estimate pulmonary-to-systemic blood flow ratio after relief of obstructive total anomalous pulmonary venous connection in two neonates with single ventricle. Distribution between systemic and pulmonary blood flow was manipulated by pharmacologic, ventilatory, and surgical interventions aimed at achieving pulmonary-to-systemic blood flow ratio of 0.5 to 1.0. Monitoring of pulmonary-to-systemic blood flow ratio facilitates appropriate balancing between tissue perfusion and oxygenation, and detects redundant ventricular volume-load.
authors.affiliation: Department of Cardiovascular Surgery, Japanese Red Cross Medical Center, Tokyo, Japan. yukihirokaneko@hotmail.com
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Hirata
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Yagyu
authors.forename: Arata
authors.initials: A
authors.lastname: Murakami
authors.forename: Shinichi
authors.initials: S
authors.lastname: Takamoto
mesh_terms: D005260:Female; D006330:Heart Defects, Congenital / Q000097:blood / Q000601:surgery*; D006352:Heart Ventricles / Q000002:abnormalities* / Q000601:surgery; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000097:blood / Q000601:surgery; D007223:Infant; D008026:Ligation; D010100:Oxygen / Q000097:blood*; D011651:Pulmonary Artery / Q000601:surgery; D011652:Pulmonary Circulation / Q000502:physiology*; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000601:surgery; D011668:Pulmonary Veno-Occlusive Disease / Q000097:blood / Q000151:congenital* / Q000601:surgery; D012039:Regional Blood Flow / Q000502:physiology; D014188:Transposition of Great Vessels / Q000097:blood / Q000601:surgery; D014683:Vena Cava, Superior; D014781:Viscera / Q000098:blood supply
chemical_list: D010100:Oxygen