title: Neurologic complications associated with influenza vaccination: two adult cases.
abstract: We describe two adult cases of neurologic complications occurring after influenza vaccination. The first case was a 62-year-old man who experienced convulsions 5 days after vaccination, and the second case was a 70-year-old man who exhibited paraplegia 7 days after vaccination. Diagnoses of acute disseminated encephalomyelitis and transverse myelitis with acute motor axonal neuropathy were made, respectively, and steroid pulse therapy and intravenous gamma globulin therapy alleviated the patients' symptoms. Although the efficacy and cost benefit of influenza vaccination have been widely accepted, such neurologic complications might occur in the elderly or even in adults.
authors.affiliation: Department of Neurology, Fujita Health University, School of Medicine, Toyoake, Aichi.
authors.forename: Naoko
authors.initials: N
authors.lastname: Nakamura
authors.forename: Kazuya
authors.initials: K
authors.lastname: Nokura
authors.forename: Takaaki
authors.initials: T
authors.lastname: Zettsu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koga
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tachi
authors.forename: Masaki
authors.initials: M
authors.lastname: Terada
authors.forename: Hideshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Yuri
authors.initials: Y
authors.lastname: Itoh
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osawa
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Ozeki
authors.forename: Hiroko
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D000367:Age Factors; D000368:Aged; D004673:Encephalomyelitis, Acute Disseminated / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control*; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D020551:Pulse Therapy, Drug; D018570:Risk Assessment; D016896:Treatment Outcome; D014611:Vaccination / Q000009:adverse effects
chemical_list: D016756:Immunoglobulins, Intravenous; D007252:Influenza Vaccines; D008775:Methylprednisolone