title: Aztreonam treatment of Pasteurella multocida cellulitis and bacteremia.
abstract: OBJECTIVE
  To report a case of Pasteurella multocida cellulitis and bacteremia treated successfully with aztreonam.
  
  
  METHODS
  An 81-year-old white man with multiple antibiotic allergies was admitted with severe cellulitis of the left arm and bacteremia due to P. multocida. The patient was treated for 14 days with aztreonam and had complete resolution of the infection.
  
  
  CONCLUSIONS
  To our knowledge, this is the first published case describing successful treatment of P. multocida cellulitis and bacteremia with aztreonam. Antimicrobials recommended for use in P. multocida infections include penicillin, ampicillin, amoxicillin, second- and third-generation cephalosporins, tetracyclines, fluoroquinolones, and trimethoprim/sulfamethoxazole. There is very little information in the current literature regarding the activity of aztreonam toward P. multocida.
  
  
  CONCLUSIONS
  This case demonstrates the potential use of aztreonam for P. multocida cellulitis and bacteremia in those instances where antibiotics of choice cannot be given.
authors.affiliation: Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK 73104, USA.
authors.forename: Jamie S
authors.initials: JS
authors.lastname: Winner
authors.forename: Chris A
authors.initials: CA
authors.lastname: Gentry
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Machado
authors.forename: Paul
authors.initials: P
authors.lastname: Cornea
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001398:Aztreonam / Q000494:pharmacology / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D001733:Bites and Stings; D002415:Cats; D002481:Cellulitis / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D010326:Pasteurella Infections / Q000188:drug therapy* / Q000382:microbiology; D016979:Pasteurella multocida / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D001398:Aztreonam