Human growth hormone for thymus reconstitution.
The thymus is an important immune organ necessary for development of new T-cells (like CD4+ and CD8+ cells.) Without some residual thymus, immune reconstitution with a wide variety of functional CD4+ cells is not believed to be possible. Thus, the state of the thymus in HIV disease and the impact of therapies on the thymus are of great interest to those researching immune restoration approaches.
D015496:CD4-Positive T-Lymphocytes / Q000166:cytology*; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology*; D002986:Clinical Trials as Topic; D015658:HIV Infections / Q000276:immunology*; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D013950:Thymus Gland / Q000503:physiopathology*
D019382:Human Growth Hormone