title: The promise of gene therapy in gastrointestinal and liver diseases.
abstract: Gene therapy consists of the transfer of genetic material to cells to achieve a therapeutic goal. In the field of gastroenterology and hepatology gene therapy has produced considerable expectation as a potential tool in the management of conditions that lack effective therapy including non-resectable neoplasms of the liver, pancreas and gastrointestinal tract, chronic viral hepatitis unresponsive to interferon therapy, liver cirrhosis, and inflammatory bowel disease.
authors.affiliation: Division of Hepatology and Gene Therapy, Department of Medicine, Clinica Universitaria, University of Navarra, Pamplona, Spain. jprieto@unav.es
authors.forename: J
authors.initials: J
authors.lastname: Prieto
authors.forename: M
authors.initials: M
authors.lastname: Herraiz
authors.forename: B
authors.initials: B
authors.lastname: Sangro
authors.forename: C
authors.initials: C
authors.lastname: Qian
authors.forename: G
authors.initials: G
authors.lastname: Mazzolini
authors.forename: I
authors.initials: I
authors.lastname: Melero
authors.forename: J
authors.initials: J
authors.lastname: Ruiz
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004067:Digestive System Neoplasms / Q000628:therapy; D005767:Gastrointestinal Diseases / Q000628:therapy*; D015316:Genetic Therapy / Q000379:methods*; D006525:Hepatitis, Viral, Human / Q000628:therapy; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000628:therapy; D008107:Liver Diseases / Q000628:therapy*