Antifeedant activity of some pentacyclic triterpene acids and their fatty acid ester analogues.
The 3-O-fatty acid ester derivatives (C(12)-C(18)) of two pentacyclic triterpenic acids, ursolic acid and oleanolic acid, were synthesized under mild esterification conditions in excellent yields (80-85%) and screened for their antifeedant activity, together with the parent acids, against the agricultural pest tobacco caterpillar larvae (Spodoptera litura F) in a no-choice laboratory study. The Urs-12-ene-28-carboxy-3beta-octadecanoate and olean-12-ene-28-carboxy-3beta-hexadecanoate were found to exhibit exceptionally potent antifeedant activities at 50 microg/cm(2) concentration, even after 48 h.
Mallavadhani
Uppuluri V
UV
Forest and Marine Products Department, Natural Resources Division, Regional Research Laboratory (CSIR), Bhubaneswar-751 013, Orissa, India. uvmavadani@yahoo.com
Mahapatra
Anita
A
Raja
S Sabitha
SS
Manjula
C
C
D000818:Animals; D029788:Diospyros / Q000737:chemistry*; D004435:Eating; D007306:Insecticides; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018411:Spodoptera / Q000502:physiology*; D014315:Triterpenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D000097245:Ursolic Acid
D007306:Insecticides; D009828:Oleanolic Acid; D014315:Triterpenes; D000097245:Ursolic Acid; C473545:olean-12-ene-28-carboxy-3-hexadecanoate; C473546:urs-12-ene-28-carboxy-3-octadecanoate