title: Evaluating alleged drinking after driving--the hip-flask defence. Part 2. Congener analysis.
abstract: The second part of this review describes the principles and practice of forensic congener analysis as an alternative way to evaluate claims of drinking alcohol after driving. Congener analysis was developed, perfected and practised in Germany as a way to evaluate hip-flask defences. This kind of defence challenge arises frequently when the drunk driving suspect is not apprehended at the wheel and especially after hit-and-run incidents. Besides ethanol and water, alcoholic beverages contain trace amounts of many other low-molecular substances, known collectively as the congeners, which impart the characteristic smell and taste to the drink. Importantly, the congener profile can be used to identify a particular kind of alcoholic beverage. Forensic congener analysis entails making a qualitative and quantitative analysis of ethanol, methanol, n-propanol and the isomers of butanol in blood and urine from the apprehended driver and comparing the results with the known congener profile of the alcoholic beverage allegedly consumed after driving. Interpreting the results of congener analysis requires knowledge about the absorption, distribution and elimination pattern of the congener alcohols, including their oxidation and conjugation reactions, and any metabolic interactions with ethanol. Complications arise if drinks with widely different congener profiles are consumed or if the same beverage was ingested both before and after driving. Despite these limitations, congener analysis can furnish compelling evidence to challenge or support claims of drinking alcohol after driving.
authors.affiliation: Department of Legal Medicine, University of Köln, Köln, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Iffland
authors.forename: A W
authors.initials: AW
authors.lastname: Jones
mesh_terms: D000433:1-Propanol / Q000097:blood* / Q000378:metabolism; D000428:Alcohol Drinking; D000435:Alcoholic Intoxication / Q000097:blood* / Q000175:diagnosis / Q000378:metabolism; D001334:Automobile Driving / Q000331:legislation & jurisprudence*; D000440:Butanols / Q000097:blood* / Q000378:metabolism; D002849:Chromatography, Gas; D000431:Ethanol / Q000097:blood* / Q000378:metabolism; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans
chemical_list: D000440:Butanols; D000431:Ethanol; D000433:1-Propanol