title: Pyomyositis as a focus of infection in hematological disorders: a report of 3 cases.
abstract: The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders.
authors.affiliation: Division of Internal Medicine, Tokyo Metropolitan Police Hospital, Tokyo, Japan.
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Hayashi
authors.forename: Miho
authors.initials: M
authors.lastname: Nozaki
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Nonaka
authors.forename: Kazuteru
authors.initials: K
authors.lastname: Ohashi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Sakamaki
authors.forename: Takeo
authors.initials: T
authors.lastname: Nomura
mesh_terms: D000328:Adult; D000368:Aged; D024881:Drug Resistance, Bacterial; D017809:Fatal Outcome; D006402:Hematologic Diseases / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008712:Methicillin; D008875:Middle Aged; D009220:Myositis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D009503:Neutropenia; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D013211:Staphylococcus aureus
chemical_list: D008712:Methicillin