title: Stacked tone-burst-evoked auditory brainstem response (ABR): preliminary findings.
abstract: In 1997, Don and his co-workers described a new method for evaluating the auditory brainstem response (ABR)--yielding the stacked-wave-V ABR--which may permit the reliable detection of even small vestibular schwannomas (VSs). However, this method requires a masking technique that may not be readily available to the clinician. Furthermore, relatively high-level noise is required and may be annoying to the patient. An alternative method that might permit the same manipulation of the ABR was thus explored whereby tone-bursts (TBs) were used to obtain frequency-specific ABRs. The goal of the study was to determine whether TBs could be used to achieve the sort of de-convolution and subsequent enhancement of wave V reported with the original method of Don et al. First, the TB-stacked ABR (wave V) was compared to that obtained using derived narrowband masked ABRs in young normal-hearing subjects. Second, the TB method was employed in subjects with unilateral VSs and in patients with unilateral sensory hearing loss in a preliminary clinical trial. The observed results are promising for the use of the TB method as an alternative approach to ABR 'stacking' and warrant further research and development of the TB method.
authors.affiliation: Unité CNRS UMR 5020, Laboratoire Neurosciences et Systèmes Sensoriels, CNRS GDR 2213 Prothèses Auditives, Hospices Civil de Lyon, Université Claude Bernard Lyon I, Lyon, France.
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Philibert
authors.forename: John D
authors.initials: JD
authors.lastname: Durrant
authors.forename: Chantal
authors.initials: C
authors.lastname: Ferber-Viart
authors.forename: Roland
authors.initials: R
authors.lastname: Duclaux
authors.forename: Evelyne
authors.initials: E
authors.lastname: Veuillet
authors.forename: Lionel
authors.initials: L
authors.lastname: Collet
mesh_terms: D000328:Adult; D000368:Aged; D001309:Auditory Threshold / Q000502:physiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000453:epidemiology; D011300:Preoperative Care; D012720:Severity of Illness Index; D013997:Time Factors; D014012:Tinnitus / Q000453:epidemiology; D014717:Vertigo / Q000453:epidemiology