title: Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine.
abstract: The vision of personalized medicine, the practice of medicine where each patient receives the most appropriate medical treatments and the most fitting dosage and combination of drugs based on his or her genetic make-up, seems to become more realistic as our knowledge about the human genome rapidly expands. We already know the reason for many types of adverse drug reactions, which are often related to polymorphic gene alleles of drug metabolizing enzymes. Moreover, insight into reasons for poor drug efficacy, often related to single nucleotide polymorphisms or larger polymorphisms in genes encoding drug target proteins, has been gained. There is a growing need to incorporate this increasingly complex body of knowledge to the standard curriculum of medical schools, so that the forthcoming generation of clinicians and researchers will be familiar with the latest developments in pharmacogenomics and medical bioinformatics, and will be capable of providing patients with the expected benefits of personalized medicine.
authors.affiliation: Department of Human Genetics and Molecular Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel. gurwitz@post.tau.ac.il
authors.forename: David
authors.initials: D
authors.lastname: Gurwitz
authors.forename: Abraham
authors.initials: A
authors.lastname: Weizman
authors.forename: Moshe
authors.initials: M
authors.lastname: Rehavi
mesh_terms: D003479:Curriculum; D016045:Human Genome Project; D006801:Humans; D020407:Internet; D010597:Pharmacogenetics / Q000193:education* / Q000639:trends; D012106:Research / Q000639:trends