title: Scleroderma renal crisis sine scleroderma during pregnancy.
abstract: Renal crisis is a serious complication of systemic sclerosis. Its occurrence prior to the development of skin sclerosis is exceedingly rare. We report a patient who developed acute renal failure during pregnancy. Renal biopsy showed features compatible with scleroderma renal crisis but typical cutaneous changes were only evident 2 months after the renal episode. The relationship between pregnancy, scleroderma activity and renal crisis is discussed.
authors.affiliation: Department of Medicine & Geriatrics, Tuen Mun Hospital, New Territories, Hong Kong, SAR China, ccmok@netvigator.com
authors.forename: C C
authors.initials: CC
authors.lastname: Mok
authors.forename: T H
authors.initials: TH
authors.lastname: Kwan
authors.forename: L
authors.initials: L
authors.lastname: Chow
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001158:Arteries / Q000473:pathology; D002216:Captopril / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D007741:Labetalol / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology
chemical_list: D000959:Antihypertensive Agents; D002216:Captopril; D007741:Labetalol