title: Vaccination campaign following an increase in incidence of serogroup C meningococcal diseases in the department of Puy-de-Dôme (France).
abstract: In the department of Puy-de-Dôme, France, 17 cases of invasive meningococcal disease C were notified between March 2001 and the first week of 2002. Among the 15 confirmed cases, 11 (73%) were serogroup C, 2 (13%) serogroup B, and 2 could not be identified. The rapid increase in the number of cases in a period of low endemicity for the rest of the country and the severity of the disease (case fatality ratio 27%, purpura fulminans 64%) led the health authorities to initiate a vaccination campaign targeting children and young adults from 2 months up to 20 years living in a limited area of the department. Around 80,000 people were immunised between 16/01/02 and 09/02/02. More than half of the 1390 immediate side effects were headache and dizziness. As of mid-March, no further case of meningococcal disease has been notified since 6 January.
authors.affiliation: Institut de Veille Sanitaire, Saint-Maurice, France.
authors.forename: D
authors.initials: D
authors.lastname: Lévy-Bruhl
authors.forename: A
authors.initials: A
authors.lastname: Perrocheau
authors.forename: M
authors.initials: M
authors.lastname: Mora
authors.forename: M-K
authors.initials: MK
authors.lastname: Taha
authors.forename: S
authors.initials: S
authors.lastname: Dromell-Chabrier
authors.forename: J
authors.initials: J
authors.lastname: Beytout
authors.forename: I
authors.initials: I
authors.lastname: Quatresous
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005602:France / Q000453:epidemiology; D006293:Health Promotion; D006801:Humans; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000517:prevention & control*; D022401:Meningococcal Vaccines / Q000008:administration & dosage*; D038542:Neisseria meningitidis, Serogroup C
chemical_list: D022401:Meningococcal Vaccines