title: New topical drugs for open-angle glaucoma.
abstract: When we reviewed the management of open-angle glaucoma in 1997, the topical drug treatments available included beta-blockers, a carbonic anhydrase inhibitor (dorzolamide), an alpha 2 agonist (apraclonidine), a prostaglandin analogue (latanoprost) and a variety of miotics and sympathomimetics. We concluded that a beta-blocker was the treatment of first choice. Here, we review seven new topical preparations that have been marketed, or had their licensed indications changed, since our earlier article.
mesh_terms: D000287:Administration, Topical; D000577:Amides; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects; D000069580:Bimatoprost; D000068438:Brimonidine Tartrate; D002257:Carbonic Anhydrase Inhibitors / Q000008:administration & dosage; D003008:Cloprostenol / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D000077338:Latanoprost; D008055:Lipids / Q000008:administration & dosage; D009883:Ophthalmic Solutions / Q000009:adverse effects; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage; D011810:Quinoxalines / Q000008:administration & dosage; D013449:Sulfonamides / Q000008:administration & dosage; D013843:Thiazines / Q000008:administration & dosage; D000069557:Travoprost
chemical_list: D000577:Amides; D000959:Antihypertensive Agents; D002257:Carbonic Anhydrase Inhibitors; D008055:Lipids; D009883:Ophthalmic Solutions; D011461:Prostaglandins F, Synthetic; D011810:Quinoxalines; D013449:Sulfonamides; D013843:Thiazines; D003008:Cloprostenol; D000068438:Brimonidine Tartrate; D000077338:Latanoprost; C111827:brinzolamide; D000069580:Bimatoprost; D000069557:Travoprost