title: [Evaluation of the Surveillance System of Acute Flaccid Paralysis in Puglia: 5 years of work].
abstract: Surveillance of acute flaccid paralysis (AFP) is the milestone to monitor the progress toward poliomyelitis eradication aim, fixed by WHA in 1988. Active AFP surveillance started in Apulia in 1997; this work evaluates five-year period activities. In this period, the total number of cases notified was 48, 7 of which were resident out of Apulia. Twenty-five were males and 23 females; the age ranged between 1 month and 15 years. Any collected serum specimens showed protective antibody levels against polioviruses. Polioviruses type 1 and type 2 Sabin-like were isolated from stool samples collected from two AFP patients. AFP surveillance targets improved in the years, with only exception, in 2001, of second serum specimen collected within 14 days because of children were discharged earlier form the hospitals. Apulia experience demonstrates the achievement of good levels of AFP surveillance targets. System sensitivity has been optimal in 2001 with a number of notified cases threefold the expected value and adequate specimen sampling (80%). Additional involved hospitals and availability of increased and dedicated human resources contributed to this outcome. The effort to achieve WHO targets for AFP surveillance needs to be maintained in next years until global certification of eradication will be declared.
authors.affiliation: Osservatorio Epidemiologico, Regione Puglia.
authors.forename: R
authors.initials: R
authors.lastname: Prato
authors.forename: M
authors.initials: M
authors.lastname: Labianca
authors.forename: A
authors.initials: A
authors.lastname: Calvario
authors.forename: A
authors.initials: A
authors.lastname: Bozzi
authors.forename: C
authors.initials: C
authors.lastname: Rizzo
authors.forename: L
authors.initials: L
authors.lastname: Fiore
authors.forename: L
authors.initials: L
authors.lastname: Vellucci
authors.forename: G
authors.initials: G
authors.lastname: Buttinelli
authors.forename: V
authors.initials: V
authors.lastname: Donati
authors.forename: P L
authors.initials: PL
authors.lastname: Lopalco
authors.forename: C
authors.initials: C
authors.lastname: Germinario
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008297:Male; D009123:Muscle Hypotonia; D010243:Paralysis / Q000175:diagnosis / Q000453:epidemiology*; D011159:Population Surveillance; D013997:Time Factors