title: [Correlation of the presence of meibomian gland dysfunction with the incidence of superficial punctate keratopathy after penetrating keratoplasty].
abstract: OBJECTIVE
  To examine the correlation of the presence of meibomian gland dysfunction(MGD) with the incidence of superficial punctate keratopathy (SPK) after penetrating keratoplasty.
  
  
  METHODS
  We studied 151 eyes of 141 patients that underwent penetrating keratoplasty. SPK and the presence of MGD were evaluated by slit-lamp examination. Tear function was evaluated by Schirmer test.
  
  
  RESULTS
  Among 151 eyes investigated, 78 eyes had neither MGD nor hypolacrimation. The number of eyes with MGD only, with hypolacrimation only, or with both MGD and hypolacrimation was 34, 23, and 16. The presence of SPK after penetrating keratoplasty was correlated with the presence of MGD 1 month or 6 months post-surgery, but no correlation was observed with the presence of hypolacrimation. There was no interaction between the presence of MGD and hypolacrimation and the incidence of SPK.
  
  
  CONCLUSIONS
  This study suggested that the active treatment of MGD is important in the post-surgery management of SPK.
authors.affiliation: Department of Biomolecular Recognition and Ophthalmology, Yamaguchi University School of Medicine, 1-1-1 Minami-kogushi, Ube 755-8505, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Shiozawa
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Morishige
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hirayama
authors.forename: Takashi
authors.initials: T
authors.lastname: Murashige
authors.forename: Tadafumi
authors.initials: T
authors.lastname: Adachi
authors.forename: Tai-ichiro
authors.initials: T
authors.lastname: Chikama
authors.forename: Teruo
authors.initials: T
authors.lastname: Nishida
mesh_terms: D003316:Corneal Diseases / Q000209:etiology*; D015352:Dry Eye Syndromes / Q000150:complications; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D008537:Meibomian Glands / Q000503:physiopathology*; D008875:Middle Aged; D011183:Postoperative Complications