title: Neurotological complications after radiosurgery versus conservative management in acoustic neuromas: a systematic review-based study.
abstract: OBJECTIVE
  Treatment modalities for acoustic neuroma (AN) include surgery, observation and gamma-knife surgery. The aim of this study was to compare neurotological complications resulting from two treatment alternatives to microsurgery: radiosurgery and observation.
  
  
  METHODS
  We conducted a systematic review of the literature dealing with radiosurgery for AN and compared the rate of neurotological complications in this population with that in a cohort of patients managed conservatively.
  
  
  RESULTS
  We found that neurotological complications, namely facial hypoesthesia (p = 0.002), hearing loss (p < 0.05) and hydrocephalus (p = 0.02), were more frequently encountered after radiosurgery than with conservative management. In contrast, we found that the risk of growth of AN is significantly higher with conservative management and that the rate of stability of the tumor did not differ significantly between the two treatments.
  
  
  CONCLUSIONS
  We prefer a conservative management regimen for patients who cannot be operated on for their AN. However, there are some difficulties inherent in this conservative management policy, namely non-compliance and difficulties in establishing the evolution of the tumor.
authors.affiliation: Department of Otolaryngology, Purpan Hospital, Toulouse, France. shin.y@chu-toulouse.fr
authors.forename: Young Je
authors.initials: YJ
authors.lastname: Shin
authors.forename: Maryse
authors.initials: M
authors.lastname: Lapeyre-Mestre
authors.forename: Inthidar
authors.initials: I
authors.lastname: Gafsi
authors.forename: Christophe
authors.initials: C
authors.lastname: Cognard
authors.forename: Olivier
authors.initials: O
authors.lastname: Deguine
authors.forename: Michel
authors.initials: M
authors.lastname: Tremoulet
authors.forename: Bernard
authors.initials: B
authors.lastname: Fraysse
mesh_terms: D005156:Facial Neuralgia / Q000209:etiology*; D005158:Facial Paralysis / Q000209:etiology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology*; D008866:Microsurgery; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D016634:Radiosurgery