Change in quality of life from before to after discharge following left ventricular assist device implantation.
BACKGROUND
Quality of life (QOL) outcomes after left ventricular assist device (LVAD) implantation from before to after hospital discharge have been examined only in a very small sample of patients. The purposes of this study are to describe change in QOL from before to after hospital discharge in LVAD patients and to determine whether being discharged with an LVAD predicts better QOL than being hospitalized with an LVAD.


METHODS
A non-random sample of 62 LVAD patients (approximately 50 years old, male, white, married, fairly well-educated) completed self-report questionnaires at >or=2 timepoints post-implant. The questionnaires (Quality of Life Index, Rating Question Form, Heart Failure Symptom Checklist, Sickness Impact Profile, LVAD Stressor Scale, Jalowiec Coping Scale), which were collated into booklets, had acceptable reliability and validity. Longitudinal analyses were performed in 2 steps using 1-sample t-tests and linear mixed effects modeling.


RESULTS
Perception of QOL and health status were fairly good both before and after discharge of LVAD patients. Discharge predicted increased satisfaction with socioeconomic areas of life; decreased overall and psychologic stress and stress related to family and friends, self-care and work/school/finances; and decreased physical and self-care disability.


CONCLUSIONS
QOL outcomes improved from before to after hospital discharge in LVAD patients awaiting heart transplantation. As LVADs potentially become available as destination therapy, in addition to being successful bridges to heart transplantation, QOL outcomes will become more important to study.
Grady
Kathleen L
KL
Rush-Presbyterian-St Luke's Medical Center, Professional Building II, Suite 439, 1725 West Harrison Street, Chicago, Illinois 60612-3824, USA.
Meyer
Peter M
PM
Mattea
Annette
A
Dressler
Diane
D
Ormaza
Sophia
S
White-Williams
Connie
C
Chillcott
Suzanne
S
Kaan
Annemarie
A
Loo
Alice
A
Todd
Barbara
B
Klemme
Annette
A
Piccione
William
W
Costanzo
Maria Rosa
MR
D001294:Attitude to Health; D006304:Health Status; D006353:Heart-Assist Devices / Q000523:psychology*; D006801:Humans; D007297:Inpatients / Q000523:psychology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000523:psychology