[Myocardial microdialysis. Importance and potential in cardiovascular research].
The microdialysis expanded mainly in the field of the neuro- and the dermopharmacology with the study of the transmitters released in the central nervous system and derm. Since ten years, this tool gained other disciplines such as cardiology and cardiovascular surgery. Indeed, the collection and the study of the molecules released in the myocardic interstitial fluid without deteriorating it functioning made microdialysis a powerful tool in the study of the extracellular environment of the cardiomyocyte. The purpose of this study is to point out the principle of the microdialysis and to show its various uses in the field of cardiovascular pharmacology.
Davani
S
S
Laboratoire de Pharmacologie, centre hospitalier universitaire, J.-Minjoz, 25030, Besançon, France. davani@ufc-chu.univ.fcomte.fr
Chocron
S
S
Muret
P
P
Mersin
N
N
Etievent
J-P
JP
Kantelip
J-P
JP
D000818:Animals; D006801:Humans; D019194:Ischemic Preconditioning; D017551:Microdialysis / Q000295:instrumentation / Q000379:methods; D009206:Myocardium / Q000378:metabolism*; D013903:Thoracic Surgery