title: [Complete surgical resection of a huge thoracic mass consisting in a localized fibrous tumor simulating a high-grade malignant neoplasm].
abstract: Solitary fibrous tumour is an infrequent neoplasm generally arising from the parietal and visceral pleura. The diagnosis may be difficult in the presence of a history of malignant disease owing to the different presentations and to radiological findings of evident invasiveness. The authors report the case of a woman with a right giant fibrous solitary tumour of the pleura twenty years after a subcutaneous mastectomy with axillary dissection and radiation therapy for breast cancer. The biopsy diagnosis was consistent with a probable solitary fibrous tumour of the pleura but the discrepancy with the radiological images and the difficult differential diagnosis versus a malignant sarcoma, possibly radio-induced, prompted us to verify the real features of the disease. The patient was submitted to a right anterolateral thoracotomy and partial sternotomy and the giant mass was resected enbloc with the phrenic nerve and diaphragm which proved to be the only structures tightly adhering to the neoplasm. Histological examination confirmed the diagnosis of a solitary fibrous tumour of the pleura. The patient is still alive and disease-free 30 months after the surgical operation. Fibrous solitary tumour is a disease generally characterised by a good prognosis but in particular cases, with unmistakable radiological findings of invasiveness, a precise diagnosis must be obtained in order to choose the most appropriate therapy.
authors.affiliation: Divisione di Chirurgia Toracica Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano.
authors.forename: Pier Paolo Brega
authors.initials: PP
authors.lastname: Massone
authors.forename: Barbara
authors.initials: B
authors.lastname: Conti
authors.forename: Cosimo
authors.initials: C
authors.lastname: Lequaglie
authors.forename: Franca
authors.initials: F
authors.lastname: Ferro
authors.forename: Ignazio
authors.initials: I
authors.lastname: Cataldo
mesh_terms: D005260:Female; D005350:Fibroma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000473:pathology / Q000601:surgery*