Angiogenesis and vascular remodeling by intussusception: from form to function.
During most instances of angiogenesis, not only are the capillaries or terminal vessels generated and modified, but the supplying vascular system is subjected to remodeling as well. Intussusception, i.e., transluminal pillar formation, is one essential mechanism for growth, arborization, bifurcation remodeling, and pruning. Complex and efficient vascular beds can thus be generated by local interactions between vascular cells and hemodynamic conditions.
Kurz
Haymo
H
Institute of Anatomy II, University of Freiburg, D-79104 Freiburg, Germany.
Burri
Peter H
PH
Djonov
Valentin G
VG
D000818:Animals; D001808:Blood Vessels / Q000166:cytology / Q000254:growth & development* / Q000502:physiology; D002196:Capillaries / Q000254:growth & development / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D018919:Neovascularization, Physiologic / Q000502:physiology*