Persistence of virus-reactive serum immunoglobulin m antibody in confirmed west nile virus encephalitis cases.
Twenty-nine laboratory-confirmed West Nile virus (WNV encephalitis patients were bled serially so that WNV-reactive immunoglobulin (Ig) M activity could be determined. Of those patients bled, 7 (60%) of 12 had anti-WNV IgM at approximately 500 days after onset. Clinicians should be cautious when interpreting serologic results from early season WNV IgM-positive patients.
Roehrig
John T
JT
Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA. jtr1@cdc.gov
Nash
Denis
D
Maldin
Beth
B
Labowitz
Anne
A
Martin
Denise A
DA
Lanciotti
Robert S
RS
Campbell
Grant L
GL
D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014901:West Nile Fever / Q000097:blood / Q000276:immunology*
D000914:Antibodies, Viral; D007075:Immunoglobulin M