title: Histology of vermiform appendix-like organ in slow loris.
abstract: The vermiform appendix-like organ (VALO) of the slow loris was investigated for its histology and immunohistochemical characteristics. The VALO has a much thinner wall with flat folded mucosa and shallower crypts than the cecal mucosa, while cellular components and population of the mucosa were similar to those of the cecum. No coalescent lymph nodules were seen in the submucosa. Immunohistochemically 5-HT-positive cells in the crypts and CD3- and CD8-positive lymphocytes in the lymph nodules were shown in the VALO as well as in the cecum. These findings suggest that the VALO is a low-differentiated vermiform appendix of the slow loris.
authors.affiliation: Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Kakuni
authors.forename: Takashi
authors.initials: T
authors.lastname: Makita
authors.forename: Hery
authors.initials: H
authors.lastname: Wijayanto
authors.forename: Eiichi
authors.initials: E
authors.lastname: Hondo
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kiso
mesh_terms: D000818:Animals; D001065:Appendix / Q000033:anatomy & histology* / Q000166:cytology / Q000378:metabolism; D017252:CD3 Complex / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes; D005260:Female; D007150:Immunohistochemistry; D008142:Lorisidae / Q000033:anatomy & histology*; D008198:Lymph Nodes / Q000166:cytology / Q000378:metabolism; D008297:Male; D012701:Serotonin / Q000378:metabolism
chemical_list: D017252:CD3 Complex; D012701:Serotonin