title: Improving planning procedure in brain biopsy: coupling frame-based stereotaxy with navigational device STP 4.0.
abstract: 37 consecutive patients with space-occupying intracerebral lesions were operated via frame-based stereotaxy. After CT-localizing of suspect lesions and computer-supported definition of entry and target coordinates a serial stereotactic biopsy was performed. Biopsy specimens allowed a satisfactory neuropathological examination and diagnostic result in 36 cases (97 %). Only three patients (8.1 %) showed an intraoperative bleeding, which was not associated with any postoperative CT-detectable hematoma, neurosurgical intervention nor with any neurological deficits. In summary we described the method of a computerized planning technique for stereotactic biopsy with the use of a special stereotactic planning program. High percentage of satisfactory neuropathological diagnoses and comfortable and accurate definition of target and entry coordinates justify computer support as a routine method.
authors.affiliation: Department of Neurosurgery, University of Leipzig, Germany. wind@medizin.uni-leipzig.de
authors.forename: D
authors.initials: D
authors.lastname: Winkler
authors.forename: C
authors.initials: C
authors.lastname: Trantakis
authors.forename: D
authors.initials: D
authors.lastname: Lindner
authors.forename: A
authors.initials: A
authors.lastname: Richter
authors.forename: J
authors.initials: J
authors.lastname: Schober
authors.forename: J
authors.initials: J
authors.lastname: Meixensberger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy / Q000295:instrumentation* / Q000379:methods*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D038361:Neuronavigation / Q000295:instrumentation* / Q000379:methods*; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods