Neurogenic motor evoked potentials: role in brachial plexus surgery. Case report.
Peripheral nerve graft repair after severe brachial plexus injury is futile if there is degeneration of motor fibers in the proximal nerve stump to which the graft must be attached. Traditional intraoperative neurophysiological assessment methods like nerve action potential (NAP) and somatosensory evoked potential (SSEP) monitoring have been used to evaluate proximal nerve stump integrity, but these methods do not allow evaluation of the integrity of motor fibers back to the anterior horn cell. Consequently, the authors used transcranial electrical stimulation and recorded neurogenic motor evoked potentials (MEPs) directly from the brachial plexus in a patient undergoing surgical repair of a complete upper brachial plexus injury (Erb palsy) to assess the functional continuity of motor fibers. In addition, selected elements of the brachial plexus were directly stimulated, and NAPs were recorded. Finally, SSEPs were recorded from the scalp after stimulation of selected elements of the brachial plexus. Neurogenic MEPs were present from the medial cord of the brachial plexus, but not the middle or upper trunk; NAPs were present from the lateral and posterior cords after middle trunk stimulation, but absent after upper trunk stimulation; and SSEPs were present after medial cord stimulation but absent after stimulation of the upper and middle trunks. For the first time, neurogenic MEPs were coupled with NAPs and SSEPs to evaluate successfully the functional status of motor fibers back to the anterior horn cell for accurate localization of the lesion sites.
Burkholder
Lee M
LM
Division of Neurosurgery and Neuroscience Research Program, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Ontario, Canada.
Houlden
David A
DA
Midha
Rajiv
R
Weiss
Erin
E
Vennettilli
Marco
M
D000200:Action Potentials; D001917:Brachial Plexus / Q000293:injuries / Q000503:physiopathology* / Q000601:surgery*; D001921:Brain / Q000503:physiopathology; D004558:Electric Stimulation; D019054:Evoked Potentials, Motor; D005073:Evoked Potentials, Somatosensory; D006801:Humans; D008297:Male; D008875:Middle Aged; D011843:Radiculopathy / Q000209:etiology / Q000503:physiopathology; D012535:Scalp / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology; D014949:Wounds, Nonpenetrating / Q000150:complications / Q000503:physiopathology* / Q000601:surgery*