[Regularity of synaptic contacts forming in the molecular layer of the cerebral cortex after brief total brain anoxia].
By the end of 10 and 90 min long total brain anoxia and on 1st, 3rd, 7th and 30th postanoxic days numerical density of synapses, shape and size of presynaptic dense projections (DP), curvature of synaptic contacts plane in molecular layer of cerebellar cortex were studied in control albino rats. Dependence between shape and extent of alterations of curvature of synaptic contacts and parameters and shape of DS was established. Maximum positive curvature of plane of synaptic contacts corresponded with maximum distance between DP, minimum height and spherical shape of DP. Maximum decline in numerical density of synapses and extent of curvature of synaptic contacts plane were found in zones of irreversible postanoxic damage of Purkinje cells.
Stepanov
S S
SS
Department of Histology and Embryology, Medical Academy of Omsk, Laboratory of Hypoxic Disturbances of Brain and Neurorehabilitation, Scientific Research Centre of Siberian Section of RAMS, Omsk.
Semchenko
V V
VV
Sergeeva
E D
ED
D000818:Animals; D002452:Cell Count; D048429:Cell Size; D002525:Cerebellar Cortex / Q000648:ultrastructure*; D002534:Hypoxia, Brain / Q000473:pathology*; D007365:Intercellular Junctions / Q000648:ultrastructure; D008297:Male; D011689:Purkinje Cells / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000648:ultrastructure*; D013997:Time Factors