[Early diagnostics of hemorrhagic fever with renal syndrome on the basis of the use of Pumala virus recombinant nucleocapsid protein].
Pumala virus recombinant nucleocapsid protein was used for the early diagnosis of haemorrhagic fever with renal syndrome. Specific IgM in the sera of patients could be determined by the IEA technique as early as on days 2-3 from the onset of the disease. The diagnostic effectiveness of the test-system was 95% and its specificity was 98%.
Veselov
S Iu
SIu
Bashkir State University, Ufa, Russia.
Khaĭbullina
S F
SF
Morzunov
S P
SP
Khasanova
S S
SS
Li
L E
LE
Garipova
M E
ME
Klimchuk
L A
LA
Speranskiĭ
V V
VV
Kulagin
V F
VF
Magazov
R Sh
RSh
D000914:Antibodies, Viral / Q000097:blood; D004926:Escherichia coli / Q000378:metabolism; D005822:Genetic Vectors; D006480:Hemorrhagic Fever with Renal Syndrome / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000097:blood; D019251:Nucleocapsid / Q000235:genetics / Q000276:immunology*; D019590:Nucleocapsid Proteins; D029262:Puumala virus / Q000276:immunology*; D011994:Recombinant Proteins / Q000276:immunology; D012680:Sensitivity and Specificity; D012698:Serologic Tests
D000914:Antibodies, Viral; D007075:Immunoglobulin M; D019590:Nucleocapsid Proteins; D011994:Recombinant Proteins; C100886:nucleocapsid protein, Puumala virus