Murine Lix1, a novel marker for substantia nigra, cortical layer 5, and hindbrain structures.
We describe the expression of Lix1 in the mouse. Starting at E8, transcripts are present in a regionalized fashion and persist throughout development. mLix1 is expressed in the cortical plate, subventricular zone, layer 5 of the postnatal cortex, the substantia nigra, dorsal root ganglia, specific nuclei of the brain stem and in spinal cord. Limb buds and facial primordia show transient expression. The prominent expression of mLix1 in the developing cerebral cortex and in the substantia nigra pars compacta makes this novel gene a candidate marker for both of these tissues.
Moeller
Carsten
C
Max Planck Institute of Experimental Endocrinology, Hanover 30625, Germany.
Yaylaoglu
Murat B
MB
Alvarez-Bolado
Gonzalo
G
Thaller
Christina
C
Eichele
Gregor
G
D000375:Aging; D000818:Animals; D000071183:Autophagy-Related Proteins; D015415:Biomarkers / Q000032:analysis; D002540:Cerebral Cortex / Q000196:embryology / Q000254:growth & development / Q000502:physiology*; D005314:Embryonic and Fetal Development; D018507:Gene Expression Regulation, Developmental; D051379:Mice; D009928:Organ Specificity; D011506:Proteins / Q000235:genetics*; D012249:Rhombencephalon / Q000196:embryology / Q000502:physiology*; D013378:Substantia Nigra / Q000196:embryology / Q000502:physiology*; D014158:Transcription, Genetic
D000071183:Autophagy-Related Proteins; D015415:Biomarkers; C499180:Lix1 protein, mouse; D011506:Proteins