TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).
Lorsbach
R B
RB
Moore
J
J
Mathew
S
S
Raimondi
S C
SC
Mukatira
S T
ST
Downing
J R
JR
D000208:Acute Disease; D000328:Adult; D000595:Amino Acid Sequence; D002648:Child; D002879:Chromosomes, Human, Pair 10; D002880:Chromosomes, Human, Pair 11; D004268:DNA-Binding Proteins / Q000235:genetics*; D005333:Fetus; D020869:Gene Expression Profiling; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D006899:Mixed Function Oxygenases; D008969:Molecular Sequence Data; D051788:Myeloid-Lymphoid Leukemia Protein; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D009928:Organ Specificity; D011518:Proto-Oncogene Proteins; D011519:Proto-Oncogenes; D014157:Transcription Factors; D014178:Translocation, Genetic
D004268:DNA-Binding Proteins; C497422:KMT2A protein, human; D015514:Oncogene Proteins, Fusion; D011518:Proto-Oncogene Proteins; D014157:Transcription Factors; D051788:Myeloid-Lymphoid Leukemia Protein; D006899:Mixed Function Oxygenases; C462539:TET1 protein, human; D011495:Histone-Lysine N-Methyltransferase