title: 1,2-cyclic sulfamidates as versatile precursors to thiomorpholines and piperazines.
abstract: [reaction: see text] 1,2-Cyclic sulfamidates undergo regiospecific nucleophilic displacement with either methyl thioglycolate or alpha-amino esters, followed by lactamization (thermal, base-mediated, or cyanide-catalyzed), to give thiomorpholin-3-ones and piperazin-2-ones.
authors.affiliation: School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Williams
authors.forename: Suda
authors.initials: S
authors.lastname: Chakthong
authors.forename: Diane
authors.initials: D
authors.lastname: Gray
authors.forename: Ron M
authors.initials: RM
authors.lastname: Lawrence
authors.forename: Timothy
authors.initials: T
authors.lastname: Gallagher