title: Holter changes resulting from right-sided and bilateral infrastellate upper thoracic sympathectomy.
abstract: BACKGROUND
  We tested the hypothesis that no right-sided dominance exists after infrastellate surgical upper-thoracic sympathectomy. We aimed to confirm whether a significant bradycardia was constant and only dependent on the right side.
  
  
  METHODS
  We performed 24-hour Holter electrocardiographic recordings in 12 patients referred for bilateral sympathectomy. Surgery was performed at two distinct times allowing for the study of the consequences of unilateral right and bilateral sympathectomy.
  
  
  RESULTS
  Heart rate was 77 +/- 8 beats per minute before surgery on the 24-hour recording and significantly decreased after bilateral (67.8 +/- 6.5 beats per minute; p < 0.05) but not after unilateral right sympathectomy. Consistently spectral analysis variables significantly changed after bilateral surgery but showed no right-sided dominance. Little effect of sympathectomy was found on the QT interval, which tended to decrease after bilateral sympathectomy.
  
  
  CONCLUSIONS
  Patients should be informed of the bradycardia resulting from sympathectomy. No right-sided dominance can be found consistently with the random distribution of substellate cardiac fibers reported in anatomic studies.
authors.affiliation: Department of Vascular Investigation and Sports Medicine, University Hospital, Angers, France. piabraham@chu-angers.fr
authors.forename: Pierre
authors.initials: P
authors.lastname: Abraham
authors.forename: Jean
authors.initials: J
authors.lastname: Berthelot
authors.forename: Jacques
authors.initials: J
authors.lastname: Victor
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Saumet
authors.forename: Jean
authors.initials: J
authors.lastname: Picquet
authors.forename: Bernard
authors.initials: B
authors.lastname: Enon
mesh_terms: D000328:Adult; D015716:Electrocardiography, Ambulatory; D005260:Female; D007839:Functional Laterality; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013562:Sympathectomy / Q000379:methods*; D013909:Thorax / Q000294:innervation