title: Fatal pulmonary artery embolism in a sickle cell patient: case report and literature review.
abstract: This article reports a rare case of fatal saddle embolism to the pulmonary artery presenting as an Acute Chest Syndrome (ACS) in a Sickle Cell patient. We present a review of the etiology, pathophysiology, clinical manifestation and management of ACS. Clinicians should be aware of the fact that a sickle cell crisis admission may represent a life-threatening process. Such awareness will help physicians to act promptly and execute proper therapeutic interventions. It is important for clinicians to be expectant of impending clinical deterioration and likewise be aware that ACS can develop in patients hospitalized for other medical or surgical conditions.
authors.affiliation: Department of Cardiology, Creighton University School of Medicine, Omaha, NE 68131, USA.
authors.forename: Dhanunjaya R
authors.initials: DR
authors.lastname: Lakkireddy
authors.forename: Robert
authors.initials: R
authors.lastname: Patel
authors.forename: Krishnamohan
authors.initials: K
authors.lastname: Basarakodu
authors.forename: James
authors.initials: J
authors.lastname: Vacek
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy