Recycling and reuse of a polymer-supported scavenger for amine sequestration.
The regeneration and reuse of a supported scavenger 1 for amine sequestration has been achieved up to three times without significant loss of activity. The scavenging process between the aldehyde resin 1 and a range of amines has been investigated in detail to determine the scope of this scavenger. Its application for the rapid purification of a small library of secondary amines 7a-j has also been demonstrated, and it has been shown that the large excess of scavenger resin used can be recovered and recycled, making this a more cost-effective process.
Guinó
Meritxell
M
Department of Chemistry, King's College London, Strand, London U.K. WC2R 2LS.
Brulé
Emilie
E
de Miguel
Yolanda R
YR
D000447:Aldehydes / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D007097:Imines / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
D000447:Aldehydes; D000588:Amines; D007097:Imines; D007202:Indicators and Reagents