[Consideration on serotoninergic syndrome based on a clinical situation ].
The diagnosis criteria for serotoninergic syndrome was first time proposed in 1991 by Sternbach, mixing clinical, biological and historical features. Drugs inducing serotonin accumulation by decreasing the synaptic recapture or increasing the serotoninergic transmission are responsible for the onset of this syndrome even in small amounts. We are describing a case of a young patient developing a comatose stage of serotoninergic syndrome as a result of Amitriptylinum and Sertralinum poisoning.
Sorodoc
L
L
Facultatea de Medicină Clinica de Urgenţe Medicale, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Frasin
M
M
Benchea
Beatrice
B
Ciuhodaru
T
T
Zaharia
Ileana
I
D018759:Adrenergic Uptake Inhibitors / Q000506:poisoning; D000328:Adult; D000639:Amitriptyline / Q000506:poisoning; D003128:Coma / Q000139:chemically induced; D004338:Drug Combinations; D005260:Female; D006801:Humans; D020230:Serotonin Syndrome / Q000139:chemically induced* / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000506:poisoning; D020280:Sertraline / Q000506:poisoning; D013406:Suicide, Attempted; D016896:Treatment Outcome
D018759:Adrenergic Uptake Inhibitors; D000639:Amitriptyline; D004338:Drug Combinations; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline