HIV resistance and tolerability issues in antiretroviral therapy.
The therapeutic regimens used to treat patients with HIV disease involve a considerable pill burden. Patient adherence to dosing schedules and other factors have been implicated in the therapeutic failure of antiretroviral agents. Alternative medical approaches to HIV disease are problematic for clinicians and scientists because many of these herbal compounds have not been assessed in well-designed research trials. A thorough investigation of alternative therapies by the medical and pharmacological sciences are needed for evaluation against existing therapies.
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Advocate Bethany Hospital, University of Illinois, College of Medicine, University of Illinois, College of Medicine, Chicago, Illinois, USA.
D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D000529:Complementary Therapies / Q000379:methods; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D018432:Drug Resistance, Multiple; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D020714:Maximum Tolerated Dose; D011379:Prognosis; D018570:Risk Assessment; D016896:Treatment Outcome
D019380:Anti-HIV Agents