title: Conversion of the enantiomers of spiro[4.4]nonane-1,6-diol into both epimeric carbaspironucleosides having natural C1' absolute configuration.
abstract: [reaction: see text] The enantiomers of spiro[4.4]nonane-1,6-diol have been transformed by different reaction pathways into the two possible carbaspironucleoside epimers with natural C1' absolute stereochemistry.
authors.affiliation: Department of Chemistry, Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio 43210, USA. paquette.1@osu.edu
authors.forename: Leo A
authors.initials: LA
authors.lastname: Paquette
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Hartung
authors.forename: David J
authors.initials: DJ
authors.lastname: France
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis; D007202:Indicators and Reagents; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D019380:Anti-HIV Agents; D007202:Indicators and Reagents; D009705:Nucleosides; D013141:Spiro Compounds; C474370:spiro(4.4)nonane-1,6-diol