Histology of vermiform appendix-like organ in slow loris.
The vermiform appendix-like organ (VALO) of the slow loris was investigated for its histology and immunohistochemical characteristics. The VALO has a much thinner wall with flat folded mucosa and shallower crypts than the cecal mucosa, while cellular components and population of the mucosa were similar to those of the cecum. No coalescent lymph nodules were seen in the submucosa. Immunohistochemically 5-HT-positive cells in the crypts and CD3- and CD8-positive lymphocytes in the lymph nodules were shown in the VALO as well as in the cecum. These findings suggest that the VALO is a low-differentiated vermiform appendix of the slow loris.
Kakuni
Masakazu
M
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
Makita
Takashi
T
Wijayanto
Hery
H
Hondo
Eiichi
E
Kiso
Yasuo
Y
D000818:Animals; D001065:Appendix / Q000033:anatomy & histology* / Q000166:cytology / Q000378:metabolism; D017252:CD3 Complex / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes; D005260:Female; D007150:Immunohistochemistry; D008142:Lorisidae / Q000033:anatomy & histology*; D008198:Lymph Nodes / Q000166:cytology / Q000378:metabolism; D008297:Male; D012701:Serotonin / Q000378:metabolism
D017252:CD3 Complex; D012701:Serotonin