title: Value of routine long bone radiographs in management of babies with a positive VDRL at the Mount Hope Women's Hospital.
abstract: This retrospective study examined the records of 44 mothers and 44 babies with a positive blood VDRL test and/or who showed symptoms of congenital syphilis at the Mount Hope Women's Hospital (MHWH), Trinidad, between June 1, 1996 and September 30, 1998. Long bone radiographs of 40/44 (91%) babies were assessed independently by two radiologists for signs of congenital syphilis and the data were analysed using frequency tables. Of the 44 mothers in the study, 34 (77%) were VDRL positive and the rest were either negative or unknown. Maternal age ranged from 14 to 39 years and most (92%) had antenatal care. Fourteen of the 34 (41%) VDRL positive mothers received treatment antenatally. All mothers were asymptomatic and none had any clinical features of syphilis. In 35/44 babies, the VDRL test was positive and in nine, the test was either negative or unknown. Twenty-six of the babies had signs suggestive of congenital syphilis and in 12, (46%) long bone radiographs revealed changes compatible with the diagnosis of congenital syphilis. Radiographic abnormalities were present only in infants with VDRL titres > 1:8.
authors.affiliation: Neonatal Unit, Mt Hope Women's Hospital, Department of Clinical Medical Sciences, Department of Public Health and Community Medicine, and the Radiology Unit, University of the West Indies, St Augustine, Trinidad and Tobago, West Indies.
authors.forename: G
authors.initials: G
authors.lastname: Busby
authors.forename: Z
authors.initials: Z
authors.lastname: Ali
authors.forename: D T
authors.initials: DT
authors.lastname: Simeon
authors.forename: O
authors.initials: O
authors.lastname: Khan
authors.forename: V
authors.initials: V
authors.lastname: Abhang
mesh_terms: D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D011859:Radiography; D012189:Retrospective Studies; D013587:Syphilis / Q000175:diagnosis; D013588:Syphilis Serodiagnosis; D013590:Syphilis, Congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging