title: Proteomic 2DE database for spot selection, automated annotation, and data analysis.
abstract: We present a software solution that enables faster and more accurate data analysis of 2DE/MALDI TOF MS data. The software supports data analysis through a number of automated data selection functions and advanced graphical tools. Once protein identities are determined using MALDI TOF MS, automated data retrieval from online databases provides biological information. The software, called 2DDB, reduces analysis time to a fraction without losing any quality compared to more manual data analysis. The database contains over 100,000 data entries, and selected parts can be reached at http://2ddb.org.
authors.affiliation: Cell & Molecular Biology, University of Lund, BMC, C13, 221 84 Lund, Sweden
authors.forename: Lars
authors.initials: L
authors.lastname: Malmström
authors.forename: Johan
authors.initials: J
authors.lastname: Malmström
authors.forename: György
authors.initials: G
authors.lastname: Marko-Varga
authors.forename: Gunilla
authors.initials: G
authors.lastname: Westergren-Thorsson
mesh_terms: D000818:Animals; D019295:Computational Biology; D030562:Databases, Protein; D006801:Humans; D040901:Proteomics