Mediterranean spotted fever during pregnancy: case presentation and literature review.
Mediterranean spotted fever (MSF) is caused by Rickettsia conorii, an obligate intracellular parasite of eukaryotic cells. Although, usually this disease has a benign course, a rapidly fatal outcome can occur even in young healthy adults. We describe a case of a 40-year-old Bedouin woman gravida 11, para 10, who was admitted at 36 weeks gestation with this rickettsial disease. During pregnancy, the treatment of choice for Mediterranean spotted fever is chloramphenicol, but it seems that Azithromycin could be another possible option.
Bentov
Yaakov
Y
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, PO Box 151, 84101 Beer-Sheva, Israel.
Sheiner
Eyal
E
Kenigsberg
Shlomit
S
Mazor
Moshe
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000907:Antibodies, Bacterial / Q000097:blood; D018912:Arabs; D001907:Boutonneuse Fever / Q000175:diagnosis* / Q000188:drug therapy; D002444:Cefuroxime / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D005260:Female; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D007557:Israel; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D020114:Rickettsia conorii / Q000276:immunology
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D002701:Chloramphenicol; D002444:Cefuroxime