title: Dynamic shifting in thalamocortical processing during different behavioural states.
abstract: Recent experiments in our laboratory have indicated that as rats shift the behavioural strategy employed to explore their surrounding environment, there is a parallel change in the physiological properties of the neuronal ensembles that define the main thalamocortical loop of the trigeminal somatosensory system. Based on experimental evidence from several laboratories, we propose that this concurrent shift in behavioural strategy and thalamocortical physiological properties provides rats with an efficient way to optimize either the detection or analysis of complex tactile stimuli.
authors.affiliation: Department of Neurobiology and Duke Centre for Neuroengineering, Duke University Medical Center, Durham, NC 27710, USA. nicoleli@neuro.duke.edu
authors.forename: Miguel A L
authors.initials: MA
authors.lastname: Nicolelis
authors.forename: Erika E
authors.initials: EE
authors.lastname: Fanselow
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D008959:Models, Neurological; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D013788:Thalamus / Q000502:physiology*