[A case of diffuse malignant mesothelioma of the pleura with bilateral chylothorax].
We describe a case of bilateral chylothorax with malignant pleural mesothelioma. A 41-year-old woman was admitted to our hospital because of dyspnea. She had no history of exposure to asbestos. A chest radiograph and chest computed tomogram (CT) on admission revealed massive bilateral pleural effusion and a large tumor with pleural thickening in the left lateral and anterior parts of the pleura and mediastinum. Biochemical tests of pleural fluid revealed chyle. Two years before, she had been diagnosed through histological and histochemical examinations as having diffuse malignant pleural mesothelioma of the epithelial type. Chest-tube drainage was performed, and pleurodesis was induced by the intrathoracic injection of OK-432 at 10 KE per dose. The chylothorax disappeared after pleurodesis. To date, reports of malignant mesothelioma with nontraumatic chylothorax have been rare.
Shimizudani
Naohiro
N
Fifth Department of Internal Medicine, Tokyo Medical University.
Morisako
Takahisa
T
Miyao
Yoshiko
Y
Ito
Masayuki
M
Hatao
Eiichi
E
Kiyoi
Kiwamu
K
Sudo
Akihike
A
Kobayashi
Katsuyuki
K
Tsuchida
Fumihiro
F
Adachi
Hideki
H
Kishi
Koji
K
Yagyu
Hisanaga
H
Oishi
Syuji
S
Nakamura
Hiroyuki
H
Matsuoka
Takeshi
T
D000328:Adult; D002916:Chylothorax / Q000209:etiology*; D005260:Female; D006801:Humans; D008654:Mesothelioma / Q000150:complications*; D010997:Pleural Neoplasms / Q000150:complications*