Ductal lavage in the screening of high-risk women.
Due to the high incidence of breast cancer and the excessively high false-positive rate of current screening technologies, adjunctive risk assessment measures are needed. Nipple aspiration cytologic analysis and random fine-needle aspirations have been proposed; however, ductal lavage and cytologic analysis of the effluent is a more sensitive and specific test. The dilemma lies in what should be done subsequent to a ductal lavage yielding malignant or atypical cells. Discussion of the proceeding procedures and potential management strategies are discussed.
Kenney
Patrick J
PJ
Department of General Surgery, Tripler Army Medical Center, MCHK-DS, Honolulu, HI 96859, USA. PKenney@mwumail.midwestern.edu
Ellison
Margarett C
MC
D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003581:Cytodiagnosis / Q000379:methods*; D005260:Female; D006801:Humans; D008403:Mass Screening; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D007507:Therapeutic Irrigation