[Tocopherol Succinate Reference Standard (Control 021) of National Institute of Health Sciences].
The raw material of tocopherol succinate was tested for the preparation of the "Tocopherol Succinate Reference Standard (Control 021)". Analytical data obtained were as follows: infrared spectrum, same as that of the Tocopherol Succinate Reference Standard (Control 981); specific absorbance, E1% 1 cm (286 nm) = 40.7; thin-layer chromatography, no impurities were detected until 50.0 micrograms; high-performance liquid chromatography (HPLC), four impurities were detected and the amount of tocopherol succinate was estimated to be 99.0%; loss on drying, 0.11%. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Reference Standard (Control 021).
Saito
Hiroyuki
H
Koide
Tatsuo
T
Iwata
Miho
M
Tanimoto
Tsuyoshi
T
D002851:Chromatography, High Pressure Liquid; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards*; D012015:Reference Standards; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards*
D014810:Vitamin E; D024505:Tocopherols