title: [Acromelanosis].
abstract: Acromelanosis is an independent disease entity, characterized by increased skin pigmentation, usually located on the acral areas of the fingers and toes. It is mostly seen in newborns or during the first years of life. Only a few cases of this entity have previously been described in the medical literature. In some of these cases, the cutaneous lesions spread to affect large parts of the skin surface. A possible association with other benign and malignant diseases has been proposed. Differential diagnosis must be made with a wide variety of systemic and dermatologic conditions, especially dermatoses with acral distribution of macular hyperpigmentation, including acropigmentation. In this article, we report a new case of acromelanosis in a 5-week-old girl showing two peculiar clinical features: associated melanosis of the genital mucosa and stabilization of the lesions after an initial phase of progression and proximal spread. In addition, the most important features of this rare cutaneous disease are discussed.
authors.affiliation: Servicio de Dermatología. Hospital 12 de Octubre. Madrid. España. jsopena@yahoo.es
authors.forename: J
authors.initials: J
authors.lastname: Sopena Barona
authors.forename: R
authors.initials: R
authors.lastname: Gamo Villegas
authors.forename: A
authors.initials: A
authors.lastname: Guerra Tapia
authors.forename: L
authors.initials: L
authors.lastname: Iglesias Díez
mesh_terms: D005260:Female; D005831:Genital Diseases, Female / Q000150:complications / Q000473:pathology*; D006229:Hand Dermatoses / Q000150:complications / Q000473:pathology*; D006801:Humans; D007223:Infant; D008548:Melanosis / Q000150:complications / Q000473:pathology*; D009092:Mucous Membrane / Q000473:pathology