Corneal neovascularization possibly associated with latanoprost therapy.
OBJECTIVE
To report a case of corneal neovascularization possibly associated with latanoprost therapy.


METHODS



METHODS
A 67-year-old man developed a progressive stromal corneal neovascularization in his right eye within eight months of a corneal trauma. At admission, he was receiving latanoprost 0.005% therapy. His topical medications were rearranged: latanoprost was replaced with carteolol hydrochloride 1% twice daily bilaterally and prednisolone acetate 1% was added twice daily in the right eye.


RESULTS
One month later, he presented regression of the corneal neovascularization and an increase in visual acuity.


CONCLUSIONS
Latanoprost, an arachidonic acid derivative, could have directly or indirectly stimulated the corneal neovascularization in this patient with a history of nonpenetrating corneal trauma.
Orhan
M
M
Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey. morhan@hacettepe.edu.tr
Kerimoğlu
H
H
Irkeç
M
M
D000287:Administration, Topical; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002354:Carteolol / Q000627:therapeutic use; D016510:Corneal Neovascularization / Q000139:chemically induced* / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007429:Intraocular Pressure; D000077338:Latanoprost; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D016896:Treatment Outcome; D014792:Visual Acuity
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D005938:Glucocorticoids; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost; D002354:Carteolol; D011239:Prednisolone