title: From words to literature in structural proteomics.
abstract: Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy - from atoms to cells - into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes.
authors.affiliation: Department of Biopharmaceutical Sciences, and California Institute for Quantitative Biomedical Research, University of California, San Francisco, California 94143, USA.
authors.forename: Andrej
authors.initials: A
authors.lastname: Sali
authors.forename: Robert
authors.initials: R
authors.lastname: Glaeser
authors.forename: Thomas
authors.initials: T
authors.lastname: Earnest
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Baumeister
mesh_terms: D000818:Animals; D003460:Crystallization; D006801:Humans; D008854:Microscopy, Electron / Q000379:methods; D008958:Models, Molecular; D011487:Protein Conformation; D020543:Proteome / Q000737:chemistry* / Q000378:metabolism*; D040901:Proteomics / Q000379:methods* / Q000639:trends*
chemical_list: D020543:Proteome