title: Plasma hormone levels in human subject during stress loads in microgravity and at readaptation to Earth's gravity.
abstract: In great part of the investigations of endocrine system functions in astronauts during space flights the plasma levels of hormones and metabolites were determined only in resting conditions, usually from one blood sample collection. Such levels reflected the psychical and physical state and new hormonal homeostasis of organism at the time of blood collection, however, the functional capacity of neuroendocrine system to respond to various stress stimuli during space flight remained unknown. The aim of present investigations was to study dynamic changes of hormone levels during the stress and metabolic loads (insulin induced hypoglycemia, physical exercise and oral glucose tolerance test) at the exposure of human subject to microgravity on the space station MIR. The responses of sympatico-adrenomedullary system to these stress and workloads were presented by Kvetnansky et al.
authors.affiliation: Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia.
authors.forename: L
authors.initials: L
authors.lastname: Macho
authors.forename: J
authors.initials: J
authors.lastname: Koska
authors.forename: L
authors.initials: L
authors.lastname: Ksinantova
authors.forename: M
authors.initials: M
authors.lastname: Vigas
authors.forename: V B
authors.initials: VB
authors.lastname: Noskov
authors.forename: A I
authors.initials: AI
authors.lastname: Grigoriev
authors.forename: R
authors.initials: R
authors.lastname: Kvetnansky
mesh_terms: D000222:Adaptation, Physiological; D001786:Blood Glucose / Q000378:metabolism*; D002096:C-Peptide / Q000097:blood / Q000378:metabolism; D005080:Exercise Test; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism; D006728:Hormones / Q000097:blood / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism; D007003:Hypoglycemia; D007328:Insulin / Q000097:blood / Q000378:metabolism; D008297:Male; D011388:Prolactin / Q000097:blood / Q000378:metabolism; D013026:Space Flight; D013312:Stress, Physiological / Q000097:blood / Q000378:metabolism*; D014893:Weightlessness
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D006728:Hormones; D007328:Insulin; D011388:Prolactin; D013006:Growth Hormone; D006854:Hydrocortisone