The C7N aminocyclitol family of natural products.
This review covers microbial secondary metabolites classified in the family of C7N aminocyclitols, a relatively new class of natural products that is increasingly gaining recognition due to their significant biomedical and agricultural uses. Their discovery and structure determinations, their biosynthetic origin, biological properties, chemical synthesis, as well as their further development for pharmaceutical uses are described. The literature from 1970 to July 2002 is reviewed, with 269 references cited.
Mahmud
Taifo
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Department of Chemistry, University of Washington, Seattle, WA 98195-1700, USA.
D020909:Acarbose; D000190:Actinomyces / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D000606:Amino Sugars; D000688:Amylose; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry / Q000145:classification / Q000378:metabolism / Q000494:pharmacology; D002867:Chromones; D005027:Ethylene Oxide; D007294:Inositol / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure; D009844:Oligosaccharides; D011758:Pyrroles; D017385:Sequence Homology; D014312:Trisaccharides
D000606:Amino Sugars; D000900:Anti-Bacterial Agents; D001688:Biological Products; D002867:Chromones; D009844:Oligosaccharides; D011758:Pyrroles; D014312:Trisaccharides; C036274:adiposin; C101442:pyralomicin 1a; D007294:Inositol; C003749:validamycins; C038505:trestatin; D000688:Amylose; D005027:Ethylene Oxide; D020909:Acarbose