title: [Tocopherol Succinate Reference Standard (Control 021) of National Institute of Health Sciences].
abstract: The raw material of tocopherol succinate was tested for the preparation of the "Tocopherol Succinate Reference Standard (Control 021)". Analytical data obtained were as follows: infrared spectrum, same as that of the Tocopherol Succinate Reference Standard (Control 981); specific absorbance, E1% 1 cm (286 nm) = 40.7; thin-layer chromatography, no impurities were detected until 50.0 micrograms; high-performance liquid chromatography (HPLC), four impurities were detected and the amount of tocopherol succinate was estimated to be 99.0%; loss on drying, 0.11%. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Reference Standard (Control 021).
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Saito
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Koide
authors.forename: Miho
authors.initials: M
authors.lastname: Iwata
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tanimoto
mesh_terms: D002851:Chromatography, High Pressure Liquid; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards*; D012015:Reference Standards; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards*
chemical_list: D014810:Vitamin E; D024505:Tocopherols