Vasculitis in a dog resembling isolated angiitis of the central nervous system in humans.
An 1-year-old dog succumbed to a seizure disorder of 18 days duration. At necropsy, an area of hemorrhage and discolored parenchyma was identified in the left pyriform lobe of the brain. Microscopic examination revealed a localized, necrotizing vasculitis with associated cerebral necrosis. Vasculitis was not present in other organs. This presentation is consistent with isolated central nervous system (CNS) angiitis, a rare form of vasculitis in humans.
Sasaki
M
M
Pool
R
R
Summers
B A
BA
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D006801:Humans; D012640:Seizures / Q000473:pathology / Q000662:veterinary; D020293:Vasculitis, Central Nervous System / Q000473:pathology* / Q000662:veterinary*