Simulated microgravity induces alteration in the central nervous system.
To investigate whether the signs of neurophysiological impairment observed in flight may be traced back to cytomorphology, we undertook a ground-based study focusing upon the architecture of cultured glial cells under simulated microgravity obtained by three-dimensional clinorotation.
Uva
B M
BM
Department of Experimental, Environmental and Applied Biology, University of Genua, Genua, Italy.
Masini
M A
MA
Sturla
M
M
Prato
P
P
Passalacqua
M
M
Giuliani
M
M
Strollo
F
F
Tagliafierro
G
G
D008841:Actin Cytoskeleton / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002490:Central Nervous System / Q000166:cytology / Q000502:physiology* / Q000648:ultrastructure; D003599:Cytoskeleton / Q000502:physiology / Q000648:ultrastructure; D018613:Microscopy, Confocal; D008870:Microtubules / Q000502:physiology* / Q000648:ultrastructure; D009457:Neuroglia / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D012399:Rotation; D018474:Weightlessness Simulation