Role of Campylobacter jejuni/coli in diarrhoea in Ile-Ife, Nigeria.
BACKGROUND
Campylobacter jejuni/coli are well established causative agents of diarrhoea. In Nigeria, gastroenteritis due to C. jejuni was first reported in northern part of the country in 1981 and the South-Western part in Ile-Ife in 1983.


OBJECTIVE
To re-examine the role of C. jejuni as an agent of diarrhoea after more than a decade at Ile-Ife, Nigeria and to determine the biological characteristics of local strains.


METHODS
A prospective case control study.


METHODS
Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC) Ile-Ife, Nigeria.


METHODS
Three hundred and three children with diarrhoea and 100 children with other medical conditions other than diarrhoea were randomly selected.


METHODS
Isolation of C. jejuni/coli from stool samples collected from the patients and controls. Biological characteristics of the isolates.


RESULTS
Fifty eight (19.1%) and 6% of the patients and controls, had the organism respectively. Campylobacter coli accounts for 53.3% of isolates. All the isolates were susceptible to erythromycin and there was no evidence of beta-lactamase production.


CONCLUSIONS
Campylobacter jejuni is an important diarrhoea agent in our environment and should be considered strongly in children with diarrhoea. Complete characterization of local, strains is necessary.
Aboderin
A O
AO
Department of Medical Microbiology and Parasitology, Faculty of Basic Medical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Smith
S I
SI
Oyelese
A O
AO
Onipede
A O
AO
Zailani
S B
SB
Coker
A O
AO
D017677:Age Distribution; D002169:Campylobacter Infections / Q000150:complications* / Q000453:epidemiology*; D017000:Campylobacter coli / Q000145:classification; D016123:Campylobacter jejuni / Q000145:classification; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D009549:Nigeria / Q000453:epidemiology; D011159:Population Surveillance; D011446:Prospective Studies; D012703:Serotyping; D017678:Sex Distribution