The role of PCI and CABG in the management of coronary artery disease in patients with diabetes.
The role of percutaneous coronary intervention (PCI) and coronary artery bypass surgery (CABG) in patients with diabetes mellitus (DM) is evolving. Data from clinical trials and observational studies are reviewed as well as current clinical practice guidelines. The importance of aggressive medical therapy to achieve recommended glycemic control targets, and management of usual risk factors in patients with coronary artery disease (CAD) cannot be overemphasized regardless of the revascularization therapy selected. Patients with type 2 diabetes are at increased risk for CAD, which is the cause of death in the majority of patients. Outcomes following PCI and CABG are worse in patients with DM compared to those without DM. This calls for randomized trials and other studies focused on patients with DM.
Frye
Robert L
RL
Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. rfrye@mayo.edu
Bell
Malcolm R
MR
Schaff
Hartzell V
HV
Holubkov
Richard
R
Detre
Katherine M
KM
D015906:Angioplasty, Balloon, Coronary; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D009316:National Institutes of Health (U.S.); D016032:Randomized Controlled Trials as Topic; D012042:Registries; D014481:United States