title: Cutaneous metastasis from pancreatic adenocarcinoma: a case report and a review of the literature.
abstract: We treated a 77-year-old Japanese man with cutaneous metastases from pancreatic adenocarcinoma. Physical examinations revealed reddish, non-tender and firm nodules in left axilla. Laboratory examination showed a remarkable elevation in the tumor markers of CA 19-9, DUPAN-2 and SPAN-1. Abdominal computed tomography showed a low-density mass in the tail of the pancreas, and histological examination of nodule in the axilla revealed a metastatic adenocarcinoma. The immunohistochemistry of CA 19-9 in the excised nodule was positive. Cutaneous metastasis from pancreatic adenocarcinoma is usually rare, and the prognosis is poor, as the disease is usually advanced.
authors.affiliation: Institute of Gastroenterology of Hofu 14-33 Eki-minami, Hofu, Yamagichi 747, Japan.
authors.forename: Hideya
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Toyokazu
authors.initials: T
authors.lastname: Kawano
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Toda
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Minamisono
authors.forename: Susumu
authors.initials: S
authors.lastname: Nagasaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Yao
authors.forename: Keizo
authors.initials: K
authors.lastname: Sugimachi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D000368:Aged; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy