title: Trans-hiatal oesophagectomy as palliative treatment for carcinoma of the oesophagus.
abstract: OBJECTIVE
  To determine the role of palliation with trans-hiatal oesophagectomy in Nigerian patients with carcinoma of the oesophagus.
  
  
  METHODS
  Prospective case series. The first series was from February 1986 to September 1987 (Series A) while the second series was from March 1989 to November 1996 (Series B).
  
  
  METHODS
  Cardiothoracic Surgery Unit (CTSU) of the University College Hospital, Ibadan, Nigeria.
  
  
  METHODS
  First series consisted of 10 consecutive operable patients with carcinoma of oesophagus seen over the period of study. The second series consisted of 21 consecutive patients with same disease.
  
  
  METHODS
  All patients had transhiatal oeosphagectomy by a two team approach and immediate placement of the freed stomach in the posterior mediastinum and cervical oesophagogastrostomy.
  
  
  RESULTS
  Patients in both series had a comparable age range of 43 - 80 years for series A and 40 - 82 years for Series B. The duration of symptoms were 2 - 6 months and 2 - 12 months respectively, for series A and B. In series A, nine patients had carcinoma of the middle-third (M1/3) of the thoracic oesophagus and one patient had carcinoma of lower-third (L1/3) of the thoracic oesophagus. In series B, 18 patients had M1/3 and three patients had L1/3 lesions. Average blood loss in series A was 1,067 mls, corresponding value for series B was 852 mls. Postoperatively, all cases were classified as stage III or stage IV disease. There were 18 complications in eight patients in series A and 22 complications in 10 patients in series B. The commonest complications in series A were pleural enteries in six patients, haemorrhage four patients (three intraoperative, one post-operative) and respiratory failure (two patients). The commonest in series B were pleural enteries in nine patients, anastomotic leaks and stenosis in four patients and respiratory failure in three patients. Hospital mortality was 50% in Series A and 14.3% in series B. The causes of death were haemorrhage and respiratory failure in series A, respiratory failure in series B. Survival period in series A of the five patients discharged was for a median of 84 months, for series B, four patients were alive at 18 months post-operative, one patient attended follow-up clinic 24 months after surgery. No other adjunctive therapy was offered to the patients.
  
  
  CONCLUSIONS
  Trans-hiatal oesophagectomy is a procedure suitable for patients with carcinoma of the oesophagus and affords palliation at an "acceptable price" among carefully selected patients with advanced carcinoma of the oesophagus.
authors.affiliation: Cardiothoracic Unit. Department of Surgery, University College Hospital, PMB 5116, Ibadan, Nigeria.
authors.forename: V O
authors.initials: VO
authors.lastname: Adegboye
authors.forename: M O
authors.initials: MO
authors.lastname: Obajimi
authors.forename: A O
authors.initials: AO
authors.lastname: Ogunseyinde
authors.forename: I A
authors.initials: IA
authors.lastname: Brimmo
authors.forename: A O
authors.initials: AO
authors.lastname: Adebo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001466:Barium Sulfate; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D003287:Contrast Media; D004210:Dissection / Q000379:methods; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D009367:Neoplasm Staging; D009549:Nigeria / Q000453:epidemiology; D010166:Palliative Care / Q000379:methods*; D018579:Patient Selection; D019106:Postoperative Hemorrhage / Q000209:etiology; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D001466:Barium Sulfate