Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.
In 2000, the chemosusceptibility of imported malaria was stable in France. All countries of infection considered, the bi-resistance to chloroquine and cycloguanil has not changed from 1996 to 2000. The monotherapy using quinine or mefloquine remains the first-line treatment to falciparum malaria. Resistance to these two antimalarials is rare in Africa and has not evolved over the past 15 years.
Ralaimazava
P
P
National reference centre for malaria chemosusceptibility, Hopital Bichat-Claude-Bernard, Paris.
Durand
R
R
Godineau
N
N
Keundjian
A
A
Jezic
Z
Z
Pradines
B
B
Bouchaud
O
O
Le Bras
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use; D004351:Drug Resistance; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D016778:Malaria, Falciparum / Q000188:drug therapy* / Q000453:epidemiology* / Q000517:prevention & control; D008297:Male; D015767:Mefloquine / Q000627:therapeutic use; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000187:drug effects*; D002727:Proguanil; D011803:Quinine / Q000627:therapeutic use; D014227:Triazines / Q000627:therapeutic use
D000962:Antimalarials; D014227:Triazines; C026009:cycloguanil; D002738:Chloroquine; D011803:Quinine; D002727:Proguanil; D015767:Mefloquine