The role of the plasminogen activation cascade in glioma cell invasion: a review.
Tumour cell invasion is a dynamic process that depends on a co-ordinated series of biochemical events. This review discusses the role of the proteolytic enzyme system, the plasminogen activation cascade, in glioma cell invasion.
Tsatas
Dina
D
Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Grattan St., Parkville, Vic. 3052, Australia.
Kaye
Andrew H
AH
D000818:Animals; D001932:Brain Neoplasms / Q000201:enzymology*; D004789:Enzyme Activation / Q000502:physiology*; D005910:Glioma / Q000201:enzymology*; D006801:Humans; D008954:Models, Biological; D010958:Plasminogen / Q000378:metabolism / Q000502:physiology*; D010960:Plasminogen Activators / Q000502:physiology; D015849:Plasminogen Inactivators; D011956:Receptors, Cell Surface / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
D015849:Plasminogen Inactivators; D011956:Receptors, Cell Surface; D010958:Plasminogen; D010960:Plasminogen Activators