title: [Beneficial effect of cibenzoline in a patient with hypertrophic obstructive cardiomyopathy complicated with idiopathic interstitial pneumonia].
abstract: A 72-year-old woman who had idiopathic interstitial pneumonia was admitted due to general fatigue. Echocardiography revealed asymmetric septal hypertrophy and systolic anterior movement of the mitral valve. In addition, Doppler echocardiography revealed a pressure gradient of 52 mmHg in the left ventricular outflow tract. Hypertrophic obstructive cardiomyopathy was diagnosed. Because she had a respiratory disease, she was treated with cibenzoline instead of beta-blockers. After treatment her pressure gradient decreased to 10 mmHg, but respiratory symptom remained unchanged. This finding suggests that cibenzoline is useful for patients with hypertrophic obstructive cardiomyopathy complicated with respiratory disease.
authors.affiliation: Second Department of Internal Medicine, Ehime University School of Medicine.
authors.forename: Makoto
authors.initials: M
authors.lastname: Saito
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Shigematsu
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Ohtsuka
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Saeki
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Ogimoto
authors.forename: Akihito
authors.initials: A
authors.lastname: Yokoyama
authors.forename: Mareomi
authors.initials: M
authors.lastname: Hamada
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D002312:Cardiomyopathy, Hypertrophic / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D017563:Lung Diseases, Interstitial / Q000150:complications*
chemical_list: D000889:Anti-Arrhythmia Agents; D007093:Imidazoles; C032151:cifenline