title: Antimicrobial susceptibilities of Shiga toxin-producing Escherichia coli isolates from pigs with edema disease in Japan.
abstract: Fifty-seven Shiga toxin-producing Escherichia coli (STEC) strains isolated from pigs with edema disease (ED) from 1997 to 2001 in Japan were examined for antimicrobial susceptibilities. The susceptibilities were compared with those of E. coli ATCC 23546 isolated from pig with ED in the 1950's. Consequently, the isolated STECs showed high susceptibility to peptides and bicozamycin in a way similar to the reference strain. On the other hand, the STECs showed low susceptibility to beta-lactams, tetracyclines, novobiocin, fosfomycin, trimethoprim, and old quinolones. It became clear that the susceptibilities of the isolated STECs had diminished in regard to antimicrobials.
authors.affiliation: Department of Veterinary Hygiene, Faculty of Agriculture, Miyazaki University, Miyazaki, Miyazaki 889-2192, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Uemura
authors.forename: Masuo
authors.initials: M
authors.lastname: Sueyoshi
authors.forename: Miki
authors.initials: M
authors.lastname: Nagayoshi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nagatomo
mesh_terms: D042462:4-Quinolones; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000494:pharmacology; D004488:Edema Disease of Swine / Q000188:drug therapy / Q000382:microbiology*; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D005578:Fosfomycin / Q000494:pharmacology; D007564:Japan; D007769:Lactams; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D009675:Novobiocin / Q000494:pharmacology; D010455:Peptides; D013552:Swine; D013754:Tetracyclines / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology
chemical_list: D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D007769:Lactams; D010455:Peptides; D013754:Tetracyclines; D009675:Novobiocin; D005578:Fosfomycin; D014295:Trimethoprim; C024504:bicozamycin