Keloidal scleroderma.
A 53-year-old woman with systemic sclerosis developed numerous cutaneous nodules, resembling keloids, on her anterior chest wall. The nodules failed to respond to therapy with topical steroid, calcipotriol, or extended photochemotherapy. This is a rare, disfiguring variant of scleroderma, unresponsive to treatment, and poorly understood.
Ling
T C
TC
The Dermatology Centre, Hope Hospital, Manchester, UK. tcling@doctors.org.uk
Herrick
A L
AL
Andrew
S M
SM
Brammah
T
T
Griffiths
C E M
CE
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001507:Beclomethasone / Q000627:therapeutic use; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007627:Keloid / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D011701:PUVA Therapy; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology / Q000628:therapy; D017211:Treatment Failure
D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids; C055085:calcipotriene; D002117:Calcitriol; D001507:Beclomethasone