title: Vasorelaxing properties and bio-guided fractionation of Cedrelopsis grevei.
abstract: The activity-guided fractionation of the hydroalcoholic extract of trunk bark of Cedrelopsis grevei led to the isolation of five coumarins, norbraylin (1), methyl-O-cedrelopsin (2), cedrecoumarin A (3), scoparone (4) and braylin (5) as a part of the constituents responsible for the vasorelaxing activity observed for the crude extract.
authors.forename: Olivier
authors.initials: O
authors.lastname: Rakotoarison
authors.forename: Ingeborg
authors.initials: I
authors.lastname: Rabenau
authors.forename: Annelise
authors.initials: A
authors.lastname: Lobstein
authors.forename: Byung-Hun
authors.initials: BH
authors.lastname: Um
authors.forename: Christa
authors.initials: C
authors.lastname: Schott
authors.forename: Robert
authors.initials: R
authors.lastname: Anton
authors.forename: Adolphe
authors.initials: A
authors.lastname: Randriantsoa
authors.forename: Ramaoson
authors.initials: R
authors.lastname: Andriantsitohaina
mesh_terms: D000818:Animals; D001011:Aorta / Q000187:drug effects; D003374:Coumarins / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects; D006801:Humans; D020128:Inhibitory Concentration 50; D029582:Meliaceae; D009638:Norepinephrine; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D014661:Vasoconstriction / Q000187:drug effects*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D003374:Coumarins; D010936:Plant Extracts; D014665:Vasodilator Agents; D009638:Norepinephrine