[Formation and structural organization of a barrier on the brain outer surface].
Using the methods of light and electron microscopy and immunocytochemistry, the barrier structures on the outer surface of the forming human brain were studied in the early prenatal period of development. The data obtained suggest that the superficial barrier in the forming brain is heteromorphous and consists of differently specialized morpho-functional complexes. The areas of contact of developing brain surface with blood capillaries of pericerebral vascular network were found to be the zone of the blood-brainbarrier formation, while the areas of the surface bordering the meningeal extracellular matrix were the zone of future liquor-brain barrier.
Otellin
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VA
Department of Morphology, RAMS Scientific Research Institute of Experimental Medicine, St. Petersburg.
Korzhevskiĭ
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DE
D001812:Blood-Brain Barrier / Q000502:physiology*; D005314:Embryonic and Fetal Development / Q000502:physiology*; D006801:Humans; D008854:Microscopy, Electron; D019579:Neocortex / Q000196:embryology / Q000502:physiology / Q000648:ultrastructure