[A clinical study of reflux oesophagites].
OBJECTIVE
To study the incidence and role of acid and bile reflux in gastroesophageal reflux disease (GERD).


METHODS
Fifty two patients with reflux symptoms were studied. All of them were performed endoscopy received acid and bile reflux monitoring.


RESULTS
Fifty two patients received acid and bile reflux monitoring, 42 patients had reflux with the main type of double-reflux (both acid and bile reflux) which was 59.5% (25/42), and with the type of the single-reflux which was 40.5% (17/42). Among single-reflux, the acid reflux was the main type about 76.4% (13/17); Among double-reflux, the degree of acid reflux was more severe, than did bile reflux; The percent of reflux oesophagites join the double-reflux patients was significant high than that in single-acid-reflux patients (P < 0.05); There was a liner correlation between acid reflux index either the frequency or the severity of reflux symptoms.


CONCLUSIONS
Double-reflux was the main type of reflux in GERD, and acid reflux was the main type among double-reflux and single-reflux. There may be a synergistic effect between acid and bile reflux. Acid reflux was the main factor for reflux symptoms.
Jiang
Jiali
J
Department of Digestion, Beijing Tongren Hospital, Capital University of Medical Science, Beijing 100730, China.
Wang
Hong
H
Wang
Minli
M
Wagn
Tianyou
T
Bi
Chunshan
C
Liu
Bin
B
D001655:Bile Reflux / Q000209:etiology*; D004942:Esophagitis, Peptic / Q000209:etiology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory