[Infertility caused by AZF microdeletions. A new case of azoospermia].
We report report a case of a man with azoospermia who was studied because of infertility. Between the causes of azoospermia and severe oligospermia, in male patients with infertility evaluations, small deletions in regions of the Y chromosome must be considered, as in our case. Regions for spermatogenesis in the Yq chromosome can be evidenced using PCR analysis. Men with azoospermia are at high risk to have small deletions in that regions. Yq chromosome deletions could be transmitted when ICSI (intracytoplasmic sperm injection) is applied. Thereafter, study of microdeletions would be included in severe infertile men.
García Rodríguez
J
J
Servicio Urología I, Hospital Central de Asturias, Asturias.
Martín Benito
J L
JL
Rodríguez Martínez
J J
JJ
Jalón Monzón
A
A
Rodríguez Faba
O
O
Fernández Gómez
J M
JM
Regadera Sejas
J
J
D000328:Adult; D002872:Chromosome Deletion; D041322:Chromosomes, Human, Y; D056426:Genetic Loci; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D029589:Seminal Plasma Proteins / Q000235:genetics*
D029589:Seminal Plasma Proteins