title: Guaiane sesquiterpenes from Amoora rohituka.
abstract: The petroleum ether extract of the stem bark of Amoora rohituka afforded two novel guaiane-derived sesquiterpenoids, 6beta,7beta-epoxyguai-4-en-3-one (1) and 6beta,7beta-epoxy-4beta,5-dihydroxyguaiane (2). The structures of 1 and 2 were determined by extensive NMR and MS analyses and by comparison of their spectral data with related compounds. The relative stereochemistry of the asymmetric centers in 1 and 2, except at C-5 of 2, were determined by selective 1D-NOESY experiments.
authors.affiliation: Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.
authors.forename: Rasheduzzaman
authors.initials: R
authors.lastname: Chowdhury
authors.forename: Choudhury M
authors.initials: CM
authors.lastname: Hasan
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Rashid
mesh_terms: D001681:Biological Assay; D002845:Chromatography / Q000379:methods; D003508:Cycloheptanes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D029582:Meliaceae / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013237:Stereoisomerism
chemical_list: D003508:Cycloheptanes; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C421026:guaiane