title: Activated recombinant factor VII for control of diffuse bleeding after implantation of ventricular assist device.
abstract: Patients with prolonged severe cardiogenic shock requiring implantation of a biventricular assist device may develop diffuse bleeding due to alteration of hepatic and renal function and subsequent coagulopathy. Bleeding control in these patients may be difficult despite massive use of blood products. We report on the successful use of recombinant activated factor VII for control of massive bleeding after implantation of a biventricular assist device in a patient with prolonged severe cardiogenic shock.
authors.affiliation: Deutsches Herzzentrum Berlin, Berlin, Germany. potapov@dhzb.de
authors.forename: Evgenij V
authors.initials: EV
authors.lastname: Potapov
authors.forename: Miralem
authors.initials: M
authors.lastname: Pasic
authors.forename: Matthias
authors.initials: M
authors.lastname: Bauer
authors.forename: Roland
authors.initials: R
authors.lastname: Hetzer
mesh_terms: D005167:Factor VII / Q000627:therapeutic use*; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use*; D012770:Shock, Cardiogenic / Q000150:complications
chemical_list: D011994:Recombinant Proteins; D005167:Factor VII