Condensation nucleation light scattering detection with ion chromatography for direct determination of glyphosate and its metabolite in water.
An ion chromatography-condensation nucleation light scattering detection (IC-CNLSD) method was successfully used to directly analyze glyphosate, a polar pesticide, and aminomethylphosaphonic acid, the major metabolite of glyphosate, in water without need of pre-treatment or derivatization. CNLSD gave a LOD of 53 ng/ml for glyphosate, which is much lower than the maximum contaminant level of 700 ng/ml for drinking water issued by the US Environmental Protection Agency. Spiked analytes in different matrixes were tested. A diluted commercial herbicide containing glyphosate was also evaluated. Compared to other reported methods, the IC-CNLSD method has no need of sample derivatization, pre-concentration, and mobile phase conductivity suppression. It is simple, fast and inexpensive. IC-CNLSD is an ideal direct detection technique for such pesticides without chromophores or fluorophores.
You
Jing
J
Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901-4409, USA.
Koropchak
John A
JA
D002853:Chromatography, Liquid / Q000379:methods*; D005998:Glycine / Q000031:analogs & derivatives* / Q000032:analysis*; D008027:Light; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D014881:Water Supply / Q000032:analysis*; D000097797:Glyphosate
D005998:Glycine; D000097797:Glyphosate