[Determination of several erythrocyte enzymes activity in patients with different tumors of the oral cavity].
Considering the influence on the molecular level of the neoplasic factors, upon several proteins, nucleic acids, one can say that some of the oncogenesis determinants are represented by genetic mutations. Free radicals, including also some organic peroxides are considered as tumour promoters, although the exact mechanism of this process in still unknown. The neoplasic disease is characterized generally by disorders of the control processes, including the one displayed on the subcellular level. Considering the enzymatic changes occurred in erythrocytes and determined by the disturbances of membrane permeability, we evaluated the response of several aggressions at the erythrocyte level, in case of maxillo-facial tumours. Our results show increase of the LDH, G-6-P-DH activity and decrease of catalase activity within the erythrocyte.
Pavel
Mariana
M
Facultatea de Medicină Stomatologică, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Foia
Liliana
L
Popescu
Eugenia
E
Iacobovici
Irina
I
Costuleanu
Natalia
N
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000201:enzymology*; D002374:Catalase / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008441:Maxillary Neoplasms / Q000201:enzymology; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000201:enzymology*; D009363:Neoplasm Proteins / Q000097:blood*
D009363:Neoplasm Proteins; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D002374:Catalase