title: Enantioselective cyanosilylation of ketones by a catalytic double-activation method employing chiral Lewis acid and achiral N-oxide catalysts.
abstract: [reaction: see text] Enantioselective addition of TMSCN to ketones is achieved by a catalytic double-activation method using 1a-Ti(IV) complex as the Lewis acid and achiral N-oxide 2 as the Lewis base to activate ketones and TMSCN, respectively.
authors.affiliation: Sichuan Key Laboratory of Green Chemistry and Technology, College of Chemistry, Sichuan University, Chengdu 610064, China.
authors.forename: Fuxue
authors.initials: F
authors.lastname: Chen
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng
authors.forename: Bo
authors.initials: B
authors.lastname: Qin
authors.forename: Guolin
authors.initials: G
authors.lastname: Zhang
authors.forename: Yaozhong
authors.initials: Y
authors.lastname: Jiang