title: Superficial granulomatous pyoderma treated with intravenous immunoglobulin.
abstract: Superficial granulomatous pyoderma is a rare variant of pyoderma gangrenosum. The superficial ulceration and vegetative margins are clinically distinctive; the suppurative and granulomatous histology is characteristic, though not pathognomonic. The condition is said to be relatively benign and more responsive to treatment than classic pyoderma gangrenosum, though published evidence of this is not always convincing. We present a case of superficial granulomatous pyoderma that was unusually aggressive, but that underwent dramatic and lasting resolution after intravenous immunoglobulin therapy.
authors.affiliation: Department of Dermatology, Royal Liverpool University Hospital, United Kingdom. cdobson8@hotmail.com
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Dobson
authors.forename: Richard A
authors.initials: RA
authors.lastname: Parslew
authors.forename: Susan
authors.initials: S
authors.lastname: Evans
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005148:Facial Dermatoses / Q000188:drug therapy / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007150:Immunohistochemistry; D008297:Male; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous