title: Characteristics of visual field progression in patients with normal-tension glaucoma with optic disk hemorrhages.
abstract: OBJECTIVE
  To study the characteristics of visual field progression in patients with normal-tension glaucoma (NTG) with optic disk hemorrhages.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Fifty-eight eyes of 58 untreated patients with NTG who had at least five reliable visual fields of the Humphrey Field Analyzer (central 30-2) within the follow-up period of more than 24 months were enrolled. Of these, 27 eyes had optic disk hemorrhages in their clinical courses. Pointwise linear regression analysis was done using total deviation values of the fields at each of 74 test locations in each patient. Progression was defined as the points of negative slopes with P <.01. A whole visual field was concentrically divided into three clusters: the areas within 10 degrees, 10 to 20 degrees, and 20 to 30 degrees. Percentages of the progressed points of the three clusters and a whole field were compared between the groups with and without optic disk hemorrhages.
  
  
  RESULTS
  No significant differences were found in patients' backgrounds, including initial mean deviation values, follow-up periods, and the number of visual field examinations between the 27 patients with optic disk hemorrhages and the 31 without. The group with optic disk hemorrhages showed significantly higher percentages of progressed points within the 10-degree area compared with the group without optic disk hemorrhages (mean +/- SD: 13.1 +/- 13.7%; 5.1 +/- 8.5%, respectively; P =.0086, Student t test), whereas no significant differences were found in the other two clusters or in a whole field.
  
  
  CONCLUSIONS
  Patients with NTG with optic disk hemorrhages tend to show visual field progression in areas within 10 degrees.
authors.affiliation: Department of Ophthalmology, Gifu University School of Medicine, Gifu, Japan. ykono-gif@umin.ac.jp
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Kono
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Sugiyama
authors.forename: Kyoko
authors.initials: K
authors.lastname: Ishida
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kitazawa
mesh_terms: D000328:Adult; D000368:Aged; D018450:Disease Progression; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000503:physiopathology*; D009901:Optic Nerve Diseases / Q000503:physiopathology*; D012166:Retinal Hemorrhage / Q000503:physiopathology*; D012189:Retrospective Studies; D014786:Vision Disorders / Q000503:physiopathology*; D014794:Visual Fields