title: [The human genome and gene expression].
abstract: Recent data estimate that the human genome contains only about twice as many genes as the c. elegans and drosophila genomes. However, this may not reflect the true difference in the complexity of the organisms, since splicing and other postranscriptional mechanisms may occur more frequently in humans. This review highlights the current knowledge of human gene structure and gene expression, with focus on mechanisms that play a role in human diseases.
authors.affiliation: Klinisk Biokemisk Afdeling, H:S Rigshospitalet, Blegdamsvej 9, DK-2100 København ø.
authors.forename: Finn Cilius
authors.initials: FC
authors.lastname: Nielsen
mesh_terms: D015870:Gene Expression / Q000235:genetics; D005815:Genetic Code; D015894:Genome, Human; D006801:Humans; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger