[Genodiagnosis and molecular typing of the pathogens for plague, cholera, and anthrax].
The paper contains a survey of published data about the use of DNA-diagnostics in indicating and identifying the causative agents of highly dangerous infections like plague, cholera and anthrax. A discussion of data about the genetic relationship between strains of the mentioned causative agents isolated from different sources by using the molecular-typing methods as well as about the evolution ties between strains of different origins is in the focus of attention. Results of comparative studies of nucleotide sequences of genomes or of individual genomes in different Yersinia pestis, Vibrio cholerae and Bacillus anthracis strains, which are indicative of the evolution of their pathogenicity, are also under discussion.
Kutyrev
V V
VV
Russian Plague Control Institute Mikrob, Saratov.
Smirnova
N I
NI
D001408:Bacillus anthracis / Q000145:classification* / Q000235:genetics; D016680:Genome, Bacterial; D005838:Genotype; D014734:Vibrio cholerae / Q000145:classification* / Q000235:genetics; D015010:Yersinia pestis / Q000145:classification* / Q000235:genetics