title: Early and definitive diagnosis of toxic shock syndrome by detection of marked expansion of T-cell-receptor VBeta2-positive T cells.
abstract: We describe two cases of early toxic shock syndrome, caused by the superantigen produced from methicillin-resistant Staphylococcus aureus and diagnosed on the basis of an expansion of T-cell-receptor VBeta2-positive T cells. One case-patient showed atypical symptoms. Our results indicate that diagnostic systems incorporating laboratory techniques are essential for rapid, definitive diagnosis of toxic shock syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan. ymatsuda@obgy.twmu.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Hidehito
authors.initials: H
authors.lastname: Kato
authors.forename: Ritsuko
authors.initials: R
authors.lastname: Yamada
authors.forename: Hiroya
authors.initials: H
authors.lastname: Okano
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ohta
authors.forename: Ken'ichi
authors.initials: K
authors.lastname: Imanishi
authors.forename: Ken
authors.initials: K
authors.lastname: Kikuchi
authors.forename: Kyouichi
authors.initials: K
authors.lastname: Totsuka
authors.forename: Takehiko
authors.initials: T
authors.lastname: Uchiyama
mesh_terms: D000328:Adult; D001427:Bacterial Toxins; D004768:Enterotoxins / Q000097:blood*; D005260:Female; D006801:Humans; D011645:Puerperal Infection / Q000175:diagnosis* / Q000382:microbiology; D012772:Shock, Septic / Q000175:diagnosis*; D018089:Superantigens
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal