Update on Charcot neuroarthropathy.
Charcot neuroarthropathy is not uncommon in diabetic patients with peripheral neuropathy. Often, the condition is misdiagnosed for cellulitis or osteomyelitis and treatment is delayed. A high index of suspicion is required in these patients to initiate appropriate treatment early. This article covers the pathogeneses of this condition and briefly describes the recent studies performed to understand the underlying etiopathogenetic factors of this devastating condition. Lastly, it mentions the recently completed multicenter trial using bisphosphonates in diabetic Charcot neuroarthropathy.
Jude
E B
EB
Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK. ejude@dc.cmht.nwest.nhs.uk
Boulton
A J
AJ
D001177:Arthropathy, Neurogenic / Q000209:etiology / Q000473:pathology / Q000628:therapy; D017719:Diabetic Foot / Q000150:complications*; D006801:Humans