Development of brain metastasis 5 years before the appearance of the primary lung cancer: "messenger metachronous metastasis".
We report a patient with a brain metastasis that presented 5 years before the primary adenocarcinoma of the lung from which it originated. The metastasis and the primary tumor were removed. To confirm their common origin, we used comparative genomic hybridization. We have named this type of metastasis "messenger metachronous metastasis." The patient remains well 79 months after the brain metastasectomy and 18 months after the lung surgery.
Furák
József
J
Division of Thoracic Surgery, University of Szeged, Szeged, Hungary. fj@surg.szote.u-szeged.hu
Troján
Imre
I
Tiszlavicz
László
L
Micsik
Tamás
T
Puskás
László G
LG
D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D001932:Brain Neoplasms / Q000235:genetics / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000235:genetics / Q000473:pathology / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D009693:Nucleic Acid Hybridization; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery*; D011013:Pneumonectomy; D018714:Radiotherapy, Adjuvant; D012086:Reoperation