[Investigation of hydrophobicity of Proteus vulgaris strains and ability of Proteus vulgaris and Proteus penneri strains to penetrate bladder membrane HCV T-29 cells ].
Proteus bacilli play a particularly important role in urinary tract infections (UTI). Fimbriae and adherence ability and hemolysins production (HpmA, HlyA) are one of the factors of pathogenicity of these bacteria. In this paper we describe the invasion of HCV T-29 transitional bladder urothelial cells carcinoma strains of P. penneri, as well as P. vulgaris strains belonging to different serogroups. The cytotoxic effect was observed at 8 hour of incubation of the tested cells with P. vulgaris O21 and the same effect (complete lysis) at 6 hours by P. vulgaris O4 (this strain manifests maximal activity in the production of HlyA hemolysin). P. penneri strains, produce different types of fimbriae, expressed similar bacterial invasiveness. The hydrophobic properties of 25 P. vulgaris strains were also tested and only 3 strains occur to have hydrophobic cell surface.
Bartodziejska
Beata
B
Zakład Immunobiologii Bakterii, Instytutu Mikrobiologii i Immunologii Uniwersytetu Łódzkiego.
Błaszczyk
Aleksandra
A
Wykrota
Marianna
M
Kwil
Iwona
I
Babicka
Dorota
D
Rózalski
Antoni
A
D002295:Carcinoma, Transitional Cell / Q000378:metabolism / Q000382:microbiology*; D006460:Hemolysin Proteins / Q000096:biosynthesis; D057927:Hydrophobic and Hydrophilic Interactions; D011511:Proteus / Q000145:classification / Q000378:metabolism / Q000472:pathogenicity; D011514:Proteus vulgaris / Q000145:classification / Q000378:metabolism* / Q000472:pathogenicity*; D012703:Serotyping; D013045:Species Specificity; D014407:Tumor Cells, Cultured; D001749:Urinary Bladder Neoplasms / Q000378:metabolism / Q000382:microbiology*; D019459:Urothelium / Q000378:metabolism / Q000382:microbiology
D006460:Hemolysin Proteins