Minimising antibiotic resistance to Staphylococcus aureus in developing countries.
OBJECTIVE
To assess the role of rational drug use and laboratory service in preventing the emergence of multiple antibiotic resistant Staphylococcus aureus in developing countries.


METHODS
Literature search on compact disk-read only memory (CD-ROM) Medline and Internet using the key words: Staphylococcus and antibiotic resistance. A few articles were manually reviewed.


METHODS
Relevant studies or articles on antibiotic resistance with special reference to Eastern Africa, region are included in the review.


METHODS
From individual studies or articles.


RESULTS
Evidence for the spread of S. aureus multiple antibiotic resistance is synchronized under the headings: Introduction, current situation, antibiotic resistance control strategies, are outlined.


CONCLUSIONS
There is need for concerted efforts between different groups to monitor changes in the epidemiology and antibiotic resistance of S. aureus. Strategies aimed at preventing transmission of resistant strains are remarkably effective when strictly enforced. Necessary attention should be given on the subject so that meaningful control measures preventing the expansion of antimicrobial resistance can be formulated, thereby ensuring the future successful treatment of Staphylococcal infections.
Kakai
R
R
Moi University, Faculty of Health Sciences, Eldoret, Kenya.
Wamola
I A
IA
D000351:Africa, Eastern / Q000453:epidemiology; D000900:Anti-Bacterial Agents / Q000191:economics / Q000627:therapeutic use; D003906:Developing Countries / Q000191:economics / Q000706:statistics & numerical data*; D024881:Drug Resistance, Bacterial; D004363:Drug Utilization; D006266:Health Education; D006282:Health Personnel / Q000193:education; D006801:Humans; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D018579:Patient Selection; D011159:Population Surveillance; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control / Q000635:transmission; D013211:Staphylococcus aureus
D000900:Anti-Bacterial Agents