title: Change in quality of life from before to after discharge following left ventricular assist device implantation.
abstract: BACKGROUND
  Quality of life (QOL) outcomes after left ventricular assist device (LVAD) implantation from before to after hospital discharge have been examined only in a very small sample of patients. The purposes of this study are to describe change in QOL from before to after hospital discharge in LVAD patients and to determine whether being discharged with an LVAD predicts better QOL than being hospitalized with an LVAD.
  
  
  METHODS
  A non-random sample of 62 LVAD patients (approximately 50 years old, male, white, married, fairly well-educated) completed self-report questionnaires at >or=2 timepoints post-implant. The questionnaires (Quality of Life Index, Rating Question Form, Heart Failure Symptom Checklist, Sickness Impact Profile, LVAD Stressor Scale, Jalowiec Coping Scale), which were collated into booklets, had acceptable reliability and validity. Longitudinal analyses were performed in 2 steps using 1-sample t-tests and linear mixed effects modeling.
  
  
  RESULTS
  Perception of QOL and health status were fairly good both before and after discharge of LVAD patients. Discharge predicted increased satisfaction with socioeconomic areas of life; decreased overall and psychologic stress and stress related to family and friends, self-care and work/school/finances; and decreased physical and self-care disability.
  
  
  CONCLUSIONS
  QOL outcomes improved from before to after hospital discharge in LVAD patients awaiting heart transplantation. As LVADs potentially become available as destination therapy, in addition to being successful bridges to heart transplantation, QOL outcomes will become more important to study.
authors.affiliation: Rush-Presbyterian-St Luke's Medical Center, Professional Building II, Suite 439, 1725 West Harrison Street, Chicago, Illinois 60612-3824, USA.
authors.forename: Kathleen L
authors.initials: KL
authors.lastname: Grady
authors.forename: Peter M
authors.initials: PM
authors.lastname: Meyer
authors.forename: Annette
authors.initials: A
authors.lastname: Mattea
authors.forename: Diane
authors.initials: D
authors.lastname: Dressler
authors.forename: Sophia
authors.initials: S
authors.lastname: Ormaza
authors.forename: Connie
authors.initials: C
authors.lastname: White-Williams
authors.forename: Suzanne
authors.initials: S
authors.lastname: Chillcott
authors.forename: Annemarie
authors.initials: A
authors.lastname: Kaan
authors.forename: Alice
authors.initials: A
authors.lastname: Loo
authors.forename: Barbara
authors.initials: B
authors.lastname: Todd
authors.forename: Annette
authors.initials: A
authors.lastname: Klemme
authors.forename: William
authors.initials: W
authors.lastname: Piccione
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Costanzo
mesh_terms: D001294:Attitude to Health; D006304:Health Status; D006353:Heart-Assist Devices / Q000523:psychology*; D006801:Humans; D007297:Inpatients / Q000523:psychology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000523:psychology