Improvements to EPA method 531.1 for the analysis of carbamates that resulted in the development of U.S. EPA Method 531.2.
This project is undertaken to fully optimize the U.S. Environmental Protection Agency Method 531.1 post-column chemistries and to incorporate recent advances in liquid chromatographic separation, post-column derivatization, and detection techniques. Sample preservation and storage stability studies establish citric acid as a suitable replacement for the caustic monochloroacetic acid in the current method and confirm its antimicrobial effectiveness. Performance of an alternate set of commercially available post-column reagents is also investigated. This research has resulted in the publication of Method 531.2, a high-performance liquid chromatographic direct injection method for the analysis of N-methylcarbamoyloximes and N-methylcarbamates using post-column derivatization and fluorescence detection.
Bassett
Martha V
MV
Shaw Environmental, Inc., 26 W. Martin Luther King Drive, Cincinnati, OH 45268, USA. bassett.margie@EPA.gov
Wendelken
Steve C
SC
Pepich
Barry V
BV
Munch
David J
DJ
D002219:Carbamates; D002713:Chlorine / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D007306:Insecticides / Q000032:analysis*; D012015:Reference Standards; D013050:Spectrometry, Fluorescence; D014481:United States; D014484:United States Environmental Protection Agency
D002219:Carbamates; D007306:Insecticides; D002713:Chlorine