[Mechanisms of the protective action of plant preparation erakond in influenza].
The results of the study of some mechanisms of the protective action of Erakond, a phytopreparation intended for use in acute influenza infection are presented. In controlled animal observations Erakond was shown to induce the synthesis of antibodies in infected and immunized mice, the production of lymphokine, endogenic interferon; to increase the phagocytic and adhesive activity of mononuclears. The preparation facilitated the normalization of the process of the peroxide oxidation of lipids in mice and rendered a positive effect on the course of the inflammatory process in the lungs of mice at the final stage of influenza infection.
Slobodeniuk
A V
AV
Urals State Medical Academy, Research Institute of Viral Preparations, Yekaterinburg.
Grigor'eva
Iu V
IuV
Pashnina
N Ia
NIa
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002448:Cell Adhesion; D007114:Immunization; D007249:Inflammation / Q000188:drug therapy; D007273:Injections, Intramuscular; D007369:Interferon Inducers / Q000627:therapeutic use*; D007372:Interferons / Q000032:analysis; D007963:Leukocytes, Mononuclear / Q000276:immunology; D015227:Lipid Peroxidation; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008222:Lymphokines / Q000032:analysis; D051379:Mice; D008807:Mice, Inbred BALB C; D009976:Orthomyxoviridae Infections / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D009195:Peroxidase / Q000378:metabolism; D010587:Phagocytosis; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use*
D000914:Antibodies, Viral; D007369:Interferon Inducers; D008222:Lymphokines; D028321:Plant Preparations; D007372:Interferons; D009195:Peroxidase