title: [Comparison of colonic J-pouch and straight coloanal anastomosis after low anterior resection for rectal carcinoma: a meta-analysis of 8 randomized trails].
abstract: OBJECTIVE
  To evaluate the effect of colonic J-pouch coloanal anastomosis after low anterior resection for mid or low rectal cancer on improving defecation and anorectal physiology.
  
  
  METHODS
  To make a meta-analysis, prospective randomized controlled trial of with or without colonic J-pouch after low anterior resection for mid or low rectal cancer was conducted. The key words included rectal cancer, J-pouch (or J-pouch) and those randomized from selected reports. The data on bowel function and physiological function of the anal canal and (neo) rectum were meta-analyzed using fixed effect model and random effect model.
  
  
  RESULTS
  Eight randomized trails including 378 patients entered this study. After one year follow-up, the functional results showed that there were significant differences in stool frequency per day, urgency and use of medication between colonic J-pouch group and straight coloanal anastomosis group. On physiological function of the anal canal and (neo) rectum, there was significant difference only in rectal compliance between the two groups. But there was no significant difference in other 4 items.
  
  
  CONCLUSIONS
  The functional improvement gained from colonic J-pouch coloanal anastomosis continues to benefit the patient with mid or low rectal cancer for at least 12 months. It is necessary to further study about the effect of colonic J-pouch coloanal anastomosis on physiological function of the anal canal and (neo) rectum.
authors.affiliation: Department of Gastrointestinopancreatic Surgery, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
authors.forename: Junsheng
authors.initials: J
authors.lastname: Peng
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zhan
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Zhao
authors.forename: Jianping
authors.initials: J
authors.lastname: Wang
authors.forename: Adamou H J
authors.initials: AH
authors.lastname: Alain
authors.forename: Jinping
authors.initials: J
authors.lastname: Ma
authors.forename: Aihua
authors.initials: A
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods; D039021:Colonic Pouches; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000601:surgery*; D016896:Treatment Outcome