title: Synchronous occurrence of glioblastoma multiforme and esophageal adenocarcinoma.
abstract: Synchronous malignancies are rare occurrences for which there may be a genetic link between two cancers or which may be simply coincidental. Although glioblastoma multiforme and esophageal adenocarcinoma have few clinical similarities there are no known biochemical or genetic links between the two malignancies. This case discussion details the synchronous occurrences of these two lesions and highlights possible clinical, biochemical, and genetic commonalities.
authors.affiliation: Section of Surgical Oncology, Department of Surgery, University of Tennessee-Memphis, 38163, USA.
authors.forename: Derrick J
authors.initials: DJ
authors.lastname: Beech
authors.forename: Atul K
authors.initials: AK
authors.lastname: Madan
authors.forename: Shaghayegh
authors.initials: S
authors.lastname: Aliabadi-Wahle
authors.forename: Angela N
authors.initials: AN
authors.lastname: Hays
authors.forename: William P
authors.initials: WP
authors.lastname: Long
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D002330:Carmustine / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D016371:Cranial Irradiation; D003680:Deglutition Disorders / Q000209:etiology; D016145:Endoscopy, Digestive System; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D016629:Esophagectomy; D004945:Esophagoscopy; D005472:Fluorouracil / Q000008:administration & dosage; D005909:Glioblastoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D010296:Parietal Lobe; D018714:Radiotherapy, Adjuvant; D012307:Risk Factors; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed
chemical_list: C453779:carmustine with prolifeprosan 20; D002945:Cisplatin; D005472:Fluorouracil; D002330:Carmustine