title: Helicobacter pylori in Indian HIV infected patients.
abstract: Helicobacter pylori is a causative organism for chronic gastritis and associated with peptic ulcer disease. Infection may be asymptomatic as well. Human immuno-deficiency virus infection predisposes to a multitude of opportunistic infections, many of them resulting in gastrointestinal symptoms. We studied the prevalence of H pylori co-infection with HIV and its correlation with gastrointestinal symptoms in HIV infected patients. Seventy-three consecutive HIV infected patients presenting to the medical out patient department of Postgraduate Institute of Medical Education & Research, Chandigarh, India, were included in the study. Antibodies (IgG) to H pylori were tested by ELISA. There were 43 males, 30 females; mean age 26.1 +/- 4.7 years. Risk factors for acquiring HIV infection was predominantly heterosexual exposure. Eleven patients presented with gastrointestinal symptoms. Thirty-five of the 73 (47.9%) patients had serological evidence of H pylori infection. Six of them had gastrointestinal symptoms. These were odynophagia in 5, dyspepsia in 4 and recent diarrhoea in 2. Twenty-four patients with H pylori infection had AIDS. There was no difference in the prevalence of H pylori infection between patients with and without AIDS.
authors.affiliation: Sexually Transmitted Diseases Research Center, Marian Villa, Westmead Hospital, Westmead, NSW 2145, Australia. asud@icpmr.wsahs.nsw.gov.au
authors.forename: A
authors.initials: A
authors.lastname: Sud
authors.forename: P
authors.initials: P
authors.lastname: Ray
authors.forename: D K
authors.initials: DK
authors.lastname: Bhasin
authors.forename: A
authors.initials: A
authors.lastname: Wanchu
authors.forename: P
authors.initials: P
authors.lastname: Bambery
authors.forename: S
authors.initials: S
authors.lastname: Singh
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis*; D015658:HIV Infections / Q000150:complications*; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D012307:Risk Factors