[Prognostic value of pharmaco-EEG in depression treated with moclobemide].
Ten women (age 41.90 +/- 5.67) with depressive episode (moderate, mild; ICD-10) were treated with moclobemide (450 mg). After 4 weeks two groups (each consists of 5 patients) with different response to the drug emerged (responders: improvement in Beck Inventory of Depression 13.6 +/- 2.9 and nonresponders: 2.0 +/- 2.4). FFT analysis of their EEG (taken before and after 4 weeks of treatment) showed some relative power differences in most bands of frequencies between groups, mostly marked for á (7-14 Hz), smaller for ä and â, but no differences for è were found. Alfa activity was relatively low after treatment in nonresponders and slightly higher in responders. However any of these results had statistical value.
Wiśniewski
Grzegorz
G
I Klinika Chorób Psychicznych AM w Gdańsku.
Jakitowicz
Janusz
J
Nowicki
Zbigniew
Z
Pankiewicz
Piotr
P
D000328:Adult; D000928:Antidepressive Agents / Q000008:administration & dosage*; D003866:Depressive Disorder / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020912:Moclobemide / Q000008:administration & dosage*; D008996:Monoamine Oxidase Inhibitors / Q000008:administration & dosage*; D011237:Predictive Value of Tests; D011379:Prognosis; D013997:Time Factors; D016896:Treatment Outcome
D000928:Antidepressive Agents; D008996:Monoamine Oxidase Inhibitors; D020912:Moclobemide