[Hepatic metastases of colorectal cancer: current therapies].
Important progress has been made in the treatment of liver metastases of advanced colorectal cancer. Surgery with curative intent, when possible, shows evidence of prolonged survival. Response rate and overall survival can be improved with modern polychemotherapy. Cytotoxic drug combinations and sequential treatments sometimes make surgery possible for initially non resectable lesions. Impact of loco-regional treatment such as hepatic arterial infusion chemotherapy must be defined in randomised trials. Radiofrequency ablation is also currently evaluated in clinical trials. In this review the benefit of each treatment is discussed.
Polus
M
M
Service d'Oncologie médicale, CHU, Sart Tilman.
Honoré
P
P
De Roover
A
A
Detry
O
O
Detroz
B
B
Jérusalem
G
G
Sautois
B
B
Fillet
G
G
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D009367:Neoplasm Staging; D016019:Survival Analysis