title: Astigmatic axis and amblyopia in childhood.
abstract: OBJECTIVE
  This study is part of a larger project whose aim is to evaluate the relationship between refractive errors and amblyopia. In an earlier study, we showed that there is a substantial increase in the prevalence of amblyopia among children with oblique astigmatism. To further evaluate this relationship, we examined children with astigmatisms of 1 dioptre or more and varying directions of the astigmatic axes.
  
  
  METHODS
  Two groups of astigmatic children, with oblique and orthogonal astigmatism, respectively, were selected for the study at 1 year of age via a general health screening programme. The most emmetropic axis was identified in each child and used in the study. Visual acuity (VA) was tested when the children were between 4 and 4.5 years of age. The presence of amblyopia, defined as difference in VA between the eyes of 0.1 log unit or more, and any increase in acuity following occlusion therapy were noted.
  
  
  RESULTS
  The angle of the astigmatic axis strongly relates to the risk of developing amblyopia. Axes +/- 15 degrees from the main axes did not affect the risk of amblyopia but oblique astigmatism significantly increased the risk of developing amblyopia (p = 0.0024).
  
  
  CONCLUSIONS
  The results accord with earlier findings that oblique astigmatism increases the risk of developing amblyopia.
authors.affiliation: Department of Clinical Neuroscience, Gotherburg University, SE-413 45 Gothenburg, Sweden. maths@oft.gu.se
authors.forename: Maths
authors.initials: M
authors.lastname: Abrahamsson
authors.forename: Johan
authors.initials: J
authors.lastname: Sjöstrand
mesh_terms: D000550:Amblyopia / Q000209:etiology* / Q000503:physiopathology; D001251:Astigmatism / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D014792:Visual Acuity