title: Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.
abstract: In 2000, the chemosusceptibility of imported malaria was stable in France. All countries of infection considered, the bi-resistance to chloroquine and cycloguanil has not changed from 1996 to 2000. The monotherapy using quinine or mefloquine remains the first-line treatment to falciparum malaria. Resistance to these two antimalarials is rare in Africa and has not evolved over the past 15 years.
authors.affiliation: National reference centre for malaria chemosusceptibility, Hopital Bichat-Claude-Bernard, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Ralaimazava
authors.forename: R
authors.initials: R
authors.lastname: Durand
authors.forename: N
authors.initials: N
authors.lastname: Godineau
authors.forename: A
authors.initials: A
authors.lastname: Keundjian
authors.forename: Z
authors.initials: Z
authors.lastname: Jezic
authors.forename: B
authors.initials: B
authors.lastname: Pradines
authors.forename: O
authors.initials: O
authors.lastname: Bouchaud
authors.forename: J
authors.initials: J
authors.lastname: Le Bras
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use; D004351:Drug Resistance; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D016778:Malaria, Falciparum / Q000188:drug therapy* / Q000453:epidemiology* / Q000517:prevention & control; D008297:Male; D015767:Mefloquine / Q000627:therapeutic use; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000187:drug effects*; D002727:Proguanil; D011803:Quinine / Q000627:therapeutic use; D014227:Triazines / Q000627:therapeutic use
chemical_list: D000962:Antimalarials; D014227:Triazines; C026009:cycloguanil; D002738:Chloroquine; D011803:Quinine; D002727:Proguanil; D015767:Mefloquine