Efficacy of ADCON-T/N after primary flexor tendon repair in Zone II: a controlled clinical trial.
A prospective double-blind, randomized, controlled clinical trial was conducted to assess the use of ADCON-T/N after flexor tendon repair in Zone II. Forty-five patients with 82 flexor tendon repairs in 50 digits completed the study. ADCON-T/N was injected into the tendon sheath after tenorrhaphy in the experimental group while the control group was not treated with ADCON-T/N. ADCON-T/N had no statistically significant effect on total active motion at 3, 6 and 12 months but the time taken to achieve the final range of motion was significantly shorter in treated patients. ADCON-treated patients had a higher rupture rate but this was not significant.
Golash
A
A
Department of Plastic Surgery, Wythenshawe Hospital, Wythenshawe, Manchester, UK.
Kay
A
A
Warner
J G
JG
Peck
F
F
Watson
J S
JS
Lees
V C
VC
D000328:Adult; D002241:Carbohydrates / Q000627:therapeutic use*; D004311:Double-Blind Method; D005383:Finger Injuries / Q000601:surgery*; D005782:Gels; D006801:Humans; D011108:Polymers / Q000627:therapeutic use*; D011446:Prospective Studies; D016059:Range of Motion, Articular; D013708:Tendon Injuries / Q000601:surgery*; D013710:Tendons / Q000601:surgery*; D000267:Tissue Adhesions / Q000517:prevention & control
C101549:ADCON-T-N; D002241:Carbohydrates; D005782:Gels; D011108:Polymers