title: Simulated microgravity induces alteration in the central nervous system.
abstract: To investigate whether the signs of neurophysiological impairment observed in flight may be traced back to cytomorphology, we undertook a ground-based study focusing upon the architecture of cultured glial cells under simulated microgravity obtained by three-dimensional clinorotation.
authors.affiliation: Department of Experimental, Environmental and Applied Biology, University of Genua, Genua, Italy.
authors.forename: B M
authors.initials: BM
authors.lastname: Uva
authors.forename: M A
authors.initials: MA
authors.lastname: Masini
authors.forename: M
authors.initials: M
authors.lastname: Sturla
authors.forename: P
authors.initials: P
authors.lastname: Prato
authors.forename: M
authors.initials: M
authors.lastname: Passalacqua
authors.forename: M
authors.initials: M
authors.lastname: Giuliani
authors.forename: F
authors.initials: F
authors.lastname: Strollo
authors.forename: G
authors.initials: G
authors.lastname: Tagliafierro
mesh_terms: D008841:Actin Cytoskeleton / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002490:Central Nervous System / Q000166:cytology / Q000502:physiology* / Q000648:ultrastructure; D003599:Cytoskeleton / Q000502:physiology / Q000648:ultrastructure; D018613:Microscopy, Confocal; D008870:Microtubules / Q000502:physiology* / Q000648:ultrastructure; D009457:Neuroglia / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D012399:Rotation; D018474:Weightlessness Simulation