Multibacterial sepsis in an alcohol abuser with hepatic cirrhosis.
An alcohol abuser with hepatitis C developed multibacterial sepsis. His mean 100% alcohol intake reached 400 ml/day. In January 2001, he suddenly experienced fever (39 degrees C) with no other symptoms. One week later, he was admitted to our hospital and was subsequently diagnosed with sepsis associated with four species of bacteria (Streptococcus constellatus, Fusobacterium mortiferum, Bacteroides thetaiotaomicron, and non-spore-forming anaerobic gram-positive bacillus). A drip infusion of imipenem/cilastatin was administrated, resulting in a successful therapeutic outcome. No underlying disorder was found except for gastric ulcers and hepatic cirrhosis. Damaged gastric mucosa was assumed to be the possible cause and route for the bacterial invasion.
Matsukawa
Yoshihiro
Y
Department of Internal Medicine I, Nihon University School of Medicine, Tokyo.
Kitamura
Noboru
N
Kaneko
Motohide
M
Yoshioka
Daijirou
D
Miki
Takaaki
T
Nishinarita
Susumu
S
Horie
Takashi
T
Hosokawa
Naoto
N
Iwasaki
Yoh
Y
Kumasaka
Kazunari
K
Kawano
Kinya
K
D000368:Aged; D000900:Anti-Bacterial Agents; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001420:Bacteria, Aerobic / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000302:isolation & purification; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013276:Stomach Ulcer / Q000150:complications / Q000175:diagnosis*
D000900:Anti-Bacterial Agents