title: Multibacterial sepsis in an alcohol abuser with hepatic cirrhosis.
abstract: An alcohol abuser with hepatitis C developed multibacterial sepsis. His mean 100% alcohol intake reached 400 ml/day. In January 2001, he suddenly experienced fever (39 degrees C) with no other symptoms. One week later, he was admitted to our hospital and was subsequently diagnosed with sepsis associated with four species of bacteria (Streptococcus constellatus, Fusobacterium mortiferum, Bacteroides thetaiotaomicron, and non-spore-forming anaerobic gram-positive bacillus). A drip infusion of imipenem/cilastatin was administrated, resulting in a successful therapeutic outcome. No underlying disorder was found except for gastric ulcers and hepatic cirrhosis. Damaged gastric mucosa was assumed to be the possible cause and route for the bacterial invasion.
authors.affiliation: Department of Internal Medicine I, Nihon University School of Medicine, Tokyo.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Matsukawa
authors.forename: Noboru
authors.initials: N
authors.lastname: Kitamura
authors.forename: Motohide
authors.initials: M
authors.lastname: Kaneko
authors.forename: Daijirou
authors.initials: D
authors.lastname: Yoshioka
authors.forename: Takaaki
authors.initials: T
authors.lastname: Miki
authors.forename: Susumu
authors.initials: S
authors.lastname: Nishinarita
authors.forename: Takashi
authors.initials: T
authors.lastname: Horie
authors.forename: Naoto
authors.initials: N
authors.lastname: Hosokawa
authors.forename: Yoh
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Kazunari
authors.initials: K
authors.lastname: Kumasaka
authors.forename: Kinya
authors.initials: K
authors.lastname: Kawano
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001420:Bacteria, Aerobic / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000302:isolation & purification; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013276:Stomach Ulcer / Q000150:complications / Q000175:diagnosis*
chemical_list: D000900:Anti-Bacterial Agents