[Ultrastructure of the cerebral cortex after exposure to gas containing hydrogen sulfide].
In experimental animals exposed to hydrogen sulfide-containing gas, electron microscopic study of cerebral cortex indicated the variability in the reaction of layer V neurons: along with neurons demonstrating irreversible damage, some cells with single signs of alteration were found. The reaction of different types of glial cells was also non-uniform. During initial 12 h following single exposure, oligodendrocytes showed the signs of intensified endocytosis. Following repeated exposures, severe destructive changes were found in myelinated nerve fibers and in single neurons, in which the karyolysis and cytoplasmic swelling were observed.
Solnyshkova
T G
TG
Laboratory of Experimental Pathology of the Cell, Scientific Research Institute of Human Morphology, Moscow.
Shakhlamov
V A
VA
Volodina
E P
EP
D000280:Administration, Inhalation; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000648:ultrastructure*; D005579:Fossil Fuels / Q000633:toxicity*; D006862:Hydrogen Sulfide / Q000633:toxicity*; D008297:Male; D008854:Microscopy, Electron; D009413:Nerve Fibers, Myelinated / Q000187:drug effects / Q000648:ultrastructure; D009457:Neuroglia / Q000187:drug effects / Q000648:ultrastructure; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D013003:Somatosensory Cortex / Q000187:drug effects / Q000648:ultrastructure
D005579:Fossil Fuels; D006862:Hydrogen Sulfide