title: Gene structure of Taenia solium paramyosin.
abstract: Paramyosin is a muscle protein that probably plays a role in the survival of the larval stage of Taenia solium during its prolonged host-parasite relationship. Here we describe the structure of the gene coding for the paramyosin of T. solium. The characterization of two clones obtained from a genomic library showed that the complete gene of paramyosin contains 13 introns delimited by conventional eukaryotic splice signals. Comparison with the paramyosin genes of Drosophila melanogaster and Caenorhabditis elegans showed a lack of conservation of the exon/intron organization in contrast to other muscle genes. No evidence of alternative splicing sites were found, excluding the possibility that T. solium expresses a mini-paramyosin like D. melanogaster.
authors.affiliation: Department of Immunology, Instituto de Investigaciones Biomédicas, UNAM, A.P. 70228, 04510 Mexico City, Mexico.
authors.forename: Laura
authors.initials: L
authors.lastname: Vargas-Parada
authors.forename: Juan Pedro
authors.initials: JP
authors.lastname: Laclette
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D019143:Evolution, Molecular; D005091:Exons; D017238:Genes, Helminth; D007438:Introns; D016415:Sequence Alignment; D041201:Taenia solium / Q000235:genetics*; D014335:Tropomyosin / Q000235:genetics*
chemical_list: D014335:Tropomyosin