Auditory thalamic nuclei projections to the temporal cortex in the rat.
Thalamocortical projections from the auditory thalamic nuclei were examined systematically in the rat, including those from the dorsal division (MGD) of the medial geniculate body (MG), which were less clearly determined in previous studies. Injections of biocytin confined in each thalamic nucleus revealed characteristic features of projections in terms of cortical areas and layers of termination. In contrast to exclusively selective projections to cortical area Te1 from the ventral division (MGV) of the MG, diffuse and selective terminations were observed in the projections from the dorsal (MGD) and medial divisions (MGM) of the MG and the suprageniculate nucleus (SG). Diffuse termination was continuous in layer I or VI of the temporal cortex, while selective termination was in layers III and IV of discrete cortical areas. In addition to diffuse termination in the upper half of layer I of cortical areas Te1, Te2d and Te3v, the MGD and SG projections formed plexuses of axons selectively in lower layer III and layer IV of Te2d and Te3v. The SG projections targeted further the dorsal bank of the perirhinal cortex (PRh), while the MGD projections targeted in part the ventral fringe of Te1. The MGM projections terminated diffusely in layer VI of Te1 and Te3v, and selectively in lower layer III and layer IV of the rostral part of Te3v. Diffuse projections to layers I and VI from the SG and MGM extended in cortical regions over the dorsal fringe of Te1. Selective dense projections to middle cortical layers of Te2d and Te3v (especially its rostral part) indicate the existence of auditory areas, which could be involved in cross-modal interaction with visual and somatosensory system, respectively. Diffuse projections are supposed to bind information processings in these areas and the primary auditory area (Te1).
Kimura
A
A
Department of Physiology, Wakayama Medical University, 811-1, 641-0012, Wakayama Kimiidera, Japan. akimura@wakayama-med.ac.jp
Donishi
T
T
Sakoda
T
T
Hazama
M
M
Tamai
Y
Y
D000818:Animals; D001303:Auditory Cortex / Q000166:cytology* / Q000502:physiology; D001306:Auditory Pathways / Q000166:cytology* / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology; D001369:Axons / Q000502:physiology / Q000648:ultrastructure*; D001931:Brain Mapping; D005829:Geniculate Bodies / Q000166:cytology* / Q000502:physiology; D008239:Lysine / Q000031:analogs & derivatives*; D008297:Male; D020656:Posterior Thalamic Nuclei / Q000166:cytology / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013003:Somatosensory Cortex / Q000166:cytology / Q000502:physiology; D014795:Visual Pathways / Q000166:cytology / Q000502:physiology
C013411:biocytin; D008239:Lysine