Cervical adenocarcinoma survival among Hispanic and white women: a multicenter cohort study.
OBJECTIVE
We compared the clinical outcome of cervical adenocarcinoma in Hispanic and white women to determine whether race was an independent predictor of survival.


METHODS
All women who were diagnosed with cervical adenocarcinoma at three institutions between 1982 and 2000 were identified. Medical records were reviewed retrospectively. Hispanic and white cohorts were matched 1:2 for age, stage of disease, date of diagnosis, tumor size, histologic subtype, grade, and invasive depth.


RESULTS
The 65 Hispanic patients were more likely to be treated at the public hospital (71% vs 14%; P <.001) than the 122 matched white patients. Most Hispanic patients (72%) and white patients (76%) presented with early (stage IA-IIA), not advanced (IIB-IVB), disease. Early (81% vs 81%, P =.65), advanced (37% vs 26%, P =.21), and overall 5-year survival rates (67% vs 68%, P =.57) were similar among Hispanic and white patients, respectively. The relative risk of race on recurrence was 1.22 (95% CI, 0.56-2.42) and on survival was 0.72 (95% CI, 0.36-1.44).


CONCLUSIONS
Hispanic race is not an independent predictor of survival in cervical adenocarcinoma.
Schorge
John O
JO
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75390, USA. john.schorge@utsouthwestern.edu
Lea
Jayanthi S
JS
Garner
Elizabeth O
EO
Duska
Linda R
LR
Miller
David S
DS
Coleman
Robert L
RL
D000230:Adenocarcinoma / Q000208:ethnology* / Q000503:physiopathology*; D000328:Adult; D015331:Cohort Studies; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000208:ethnology; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000208:ethnology* / Q000503:physiopathology*; D044465:White People / Q000706:statistics & numerical data*