title: Changes in the distribution of labeled retinal ganglion cells after an implant of DiI into the optic nerve in the chick embryos.
abstract: Changes in the distribution of retinal ganglion cells (RGCs) were studied using the retrograde labeling of DiI in chicks and chick embryos. The small retinal area filled with labeled RGCs was observed in the retinal fundus on E8. The labeled retinal area expanded radially toward the peripheral retina as the retina grew, and finally occupied a whole retina by P1. The temporal retina was labeled more rapidly than in the nasal retina. The observed-increasing rate of the labeled area was corrected with the growing rate of the retina. Consequently, the corrected-increasing rate of the labeled area was estimated to be about 390% between E8 and E11, and 20-50% after E11. This means that spreading speed of the maturated RGCs lowered until 1/10-1/20 after E11.
authors.affiliation: Laboratory of Veterinary Anatomy, College of Animal Medicine, China Agricultural University, Beijing, China.
authors.forename: Yaoxing
authors.initials: Y
authors.lastname: Chen
authors.forename: Man
authors.initials: M
authors.lastname: Hu
authors.forename: Hideshi
authors.initials: H
authors.lastname: Shibata
authors.forename: Jumpei
authors.initials: J
authors.lastname: Naito
mesh_terms: D000818:Animals; D002232:Carbocyanines / Q000032:analysis; D002642:Chick Embryo; D005314:Embryonic and Fetal Development; D009900:Optic Nerve; D012160:Retina / Q000166:cytology* / Q000196:embryology*; D012165:Retinal Ganglion Cells / Q000166:cytology* / Q000502:physiology*
chemical_list: D002232:Carbocyanines