Annexin 1: an endogenous anti-inflammatory protein.
A hallmark of inflammation is the mobilization of blood-borne leukocytes across microvessels to kill and remove the invading pathogen. For its damaging potential, leukocyte movement is finely regulated, and endogenous pathways exist to ensure the time dependency of this process. Annexin 1 and its receptor(s) are one example of these pathways.
Perretti
Mauro
M
The William Harvey Research Institute, London EC1M 6BQ, United Kingdom.
Gavins
Felicity N E
FN
D000818:Animals; D017302:Annexins / Q000494:pharmacology / Q000502:physiology*; D006801:Humans; D018836:Inflammation Mediators / Q000494:pharmacology / Q000502:physiology*
D017302:Annexins; D018836:Inflammation Mediators