UCB 62045: pharmacology of a novel, dual-function anti-inflammatory agent with histamine type 1 receptor antagonist and 5-lipoxygenase inhibitor activity.
Selig
William M
WM
UCB Research, Inc., Cambridge, MA 02139, USA. william.selig@ucb-group.com
Bayless
Lynn
L
Libertine
Lyn
L
Eckman
Joseph B
JB
Wypij
Donna M
DM
Wels
Bruce F
BF
Eckert
Maria
M
Young
Michelle A
MA
Nicolas
Jean M
JM
Scannell
Ralph T
RT
Ellis
James L
JL
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001094:Arachidonate 5-Lipoxygenase / Q000494:pharmacology*; D016084:Bronchoconstriction / Q000187:drug effects*; D004195:Disease Models, Animal; D006168:Guinea Pigs; D006633:Histamine Antagonists / Q000494:pharmacology*; D016859:Lipoxygenase Inhibitors
D000893:Anti-Inflammatory Agents; D006633:Histamine Antagonists; D016859:Lipoxygenase Inhibitors; D001094:Arachidonate 5-Lipoxygenase