title: Varicella vaccination during early pregnancy: a cause of in utero miliary fetal tissue calcifications and hydrops?
abstract: BACKGROUND
  It is the purpose of this article to describe a suspected association of inadvertent vaccination with varicella vaccine during early pregnancy with the subsequent development of in utero miliary fetal tissue calcifications and fetal hydrops detected by sonogram at 15 weeks of gestation.
  
  
  METHODS
  This is a case presentation of a pregnant patient who received varicella vaccination during the same menstrual cycle that she became pregnant, and is supplemented by a literary review. The fetus developed miliary fetal tissue calcifications and fetal hydrops detected by a targeted sonogram at 15 weeks gestation.
  
  
  CONCLUSIONS
  Varicella vaccination during early pregnancy may be a cause of miliary fetal tissue calcifications and fetal hydrops.
authors.affiliation: Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, Newark, New Jersey 07103-2714, USA. apuzzijj@umdnj.edu
authors.forename: Joseph
authors.initials: J
authors.lastname: Apuzzio
authors.forename: Vijaya
authors.initials: V
authors.lastname: Ganesh
authors.forename: Leslie
authors.initials: L
authors.lastname: Iffy
authors.forename: Anthony
authors.initials: A
authors.lastname: Al-Khan
mesh_terms: D000032:Abortion, Therapeutic; D000328:Adult; D002114:Calcinosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D002644:Chickenpox / Q000517:prevention & control*; D019433:Chickenpox Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005333:Fetus / Q000473:pathology; D006801:Humans; D015160:Hydrops Fetalis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018570:Risk Assessment; D012720:Severity of Illness Index; D016216:Ultrasonography, Prenatal; D014611:Vaccination / Q000009:adverse effects
chemical_list: D019433:Chickenpox Vaccine