Osteosarcoma arising from the skull--case report.
A 20-year-old male presented with an osteosarcoma in the right parieto-occipital bone occurring as a painless occipital lump which had rapidly enlarged in the 6 months prior to admission. The neuroimaging appearance resembled intraosseous meningioma. Gross total resection of the tumor was achieved. The final histological diagnosis was osteosarcoma. Osteosarcomas of craniofacial region have a better prognosis than those of the skeletal bones, and distant metastasis is rare. Local recurrence is the most significant factor contributing to poor outcome. Complete excision with negative margins is the key to a better outcome. Adjuvant therapy may be an option in cases of incomplete excision. Advances in target chemotherapy may diminish the significant morbidity associated with these lesions.
Kanazawa
Ryuzaburo
R
Department of Neurosurgery, Nippon Medical School, Tokyo, Japan. ryu@nms.ac.jp
Yoshida
Daizo
D
Takahashi
Hiroshi
H
Matsumoto
Koshi
K
Teramoto
Akira
A
D000328:Adult; D000792:Angiography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008576:Meningeal Arteries / Q000000981:diagnostic imaging; D012516:Osteosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed