title: Serial exercise performance in children with surgically corrected congenital aortic stenosis.
abstract: We examined serial exercise test performance in children with congenital aortic stenosis (AS) treated surgically compared to that of nonoperated children with mild to moderate AS. Maximal treadmill exercise data were assessed in 21 children 5.5 +/- 3.8 years after aortic valve (AO) surgery. Patients had undergone the Ross procedure (n = 6) or previous aortic valvotomy, balloon valvuloplasty, or neonatal aortic valvotomy (n = 15). Follow-up treadmill tests were conducted 3.7 +/- 2.8 years later. Data were compared to those of 19 nonoperated AS patients (mean gradient by echocardiogram <50 mmHg). These patients were exercised 3.6 +/- 3.2 years apart. Endurance time, heart rate, systemic blood pressure, and electrocardiogram were compared as repeated measures between tests and to age- and sex-matched normative data. Postsurgical children with AS had normal endurance times despite low peak heart rates on the initial test, and they maintained endurance over time. Nonoperated children with mean AO gradients <50 mmHg also had normal endurance times on the initial test but increased endurance over 3.6 years. Children with operated and nonoperated AS were able to reach or exceed normal endurance times, which may make it difficult to achieve compliance to imposed activity restrictions in this population.
authors.affiliation: Dr. Scholl Cardiac Exercise Laboratory, Division of Cardiology, Children's Memorial Hospital, Chicago, IL 60614, USA.
authors.forename: B M
authors.initials: BM
authors.lastname: Mitchell
authors.forename: J F
authors.initials: JF
authors.lastname: Strasburger
authors.forename: J E
authors.initials: JE
authors.lastname: Hubbard
authors.forename: H U
authors.initials: HU
authors.lastname: Wessel
mesh_terms: D000293:Adolescent; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000601:surgery*; D001795:Blood Pressure Determination; D002648:Child; D015331:Cohort Studies; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000601:surgery*; D006334:Heart Function Tests; D006339:Heart Rate; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D010807:Physical Endurance; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013997:Time Factors