Bioinorganic chemistry in the postgenomic era.
Genome sequencing has revolutionized all fields of life sciences. Bioinorganic chemistry is certainly not immune to this influence, which is presenting unprecedented challenges. A new goal for bioinorganic chemistry is the investigation of the linkages between inorganic elements and genomic information. This requires new advancements andor the development of new expertise in fields such as bioinformatics and genetics but also provides a driving force to push forward the exploitation of traditional analytical techniques and spectroscopic tools. The "case study" of metal homeostasis in cells is discussed to provide a flavor of the current evolution of the field.
Bertini
Ivano
I
Magnetic Resonance Center, University of Florence, Via Luigi Sacconi 6, 50019 Sesto Fiorentino, Italy. bertini@cerm.unifi.it
Rosato
Antonio
A
D001483:Base Sequence; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics; D015393:Chemistry, Bioinorganic / Q000379:methods*; D005823:Genetics / Q000639:trends*; D016678:Genome; D008670:Metals / Q000378:metabolism; D008958:Models, Molecular; D017433:Protein Structure, Secondary
D002352:Carrier Proteins; D008670:Metals