title: Breast cancer cell lines: friend or foe?
abstract: The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.
authors.affiliation: Molecular Medicine Unit, University of Leeds, Leeds, UK.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Burdall
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Hanby
authors.forename: Mark R J
authors.initials: MR
authors.lastname: Lansdown
authors.forename: Valerie
authors.initials: V
authors.lastname: Speirs
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D018929:Cell Culture Techniques / Q000379:methods / Q000592:standards*; D006801:Humans; D011786:Quality Control; D014407:Tumor Cells, Cultured