Construct validity of the abbreviated mental test in older medical inpatients.
OBJECTIVE
To evaluate validity and internal structure of the Abbreviated Mental Test (AMT), and to assess the dependence of the internal structure upon the characteristics of the patients examined.


METHODS
Cross-sectional examination using data from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA) database.


METHODS
Twenty-four acute care wards of Geriatrics or General Medicine.


METHODS
Two thousand eight hundred and eight patients consecutively admitted over a 4-month period.


METHODS
Demographic characteristics, functional status, medical conditions and performance on AMT were collected at discharge. Sensitivity, specificity and predictive values of the AMT <7 versus a diagnosis of dementia made according to DSM-III-R criteria were computed. The internal structure of AMT was assessed by principal component analysis. The analysis was performed on the whole population and stratified for age (<65, 65-80 and >80 years), gender, education (<6 or >5 years) and presence of congestive heart failure (CHF).


RESULTS
AMT achieved high sensitivity (81%), specificity (84%) and negative predictive value (99%), but a low positive predictive value of 25%. The principal component analysis isolated two components: the former component represents the orientation to time and space and explains 45% of AMT variance; the latter is linked to memory and attention and explains 13% of variance. Comparable results were obtained after stratification by age, gender or education. In patients with CHF, only 48.3% of the cumulative variance was explained; the factor accounting for most (34.6%) of the variance explained was mainly related to the three items assessing memory.


CONCLUSIONS
AMT >6 rules out dementia very reliably, whereas AMT <7 requires a second level cognitive assessment to confirm dementia. AMT is bidimensional and maintains the same internal structure across classes defined by selected social and demographic characteristics, but not in CHF patients. It is likely that its internal structure depends on the type of patients. The use of a sum-score could conceal some part of the information provided by the AMT.
Antonelli Incalzi
R
R
Centro di Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Roma, Italia.
Cesari
M
M
Pedone
C
C
Carosella
L
L
Carbonin
P U
PU
D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D003625:Data Collection; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales / Q000592:standards*; D012680:Sensitivity and Specificity