Primary antiphospholipid antibody syndrome and cardiac involvement in a child.
We report a case of polyvalvar disease and recurrent thrombosis in a 2-year-old boy due to primary antiphospholipid antibody syndrome. His diagnosis was delayed, and he was treated for other diagnoses, including culture-negative endocarditis. Primary antiphospholipid antibody syndrome is rarely discussed in the pediatric cardiology literature, and this case highlights the need for early diagnosis to prevent recurrent valve dysfunction and thrombosis.
Clauss
S B
SB
Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, USA.
Manco-Johnson
M J
MJ
Quivers
E
E
Takemoto
C
C
Spevak
P J
PJ
D017153:Antibodies, Anticardiolipin / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D003951:Diagnostic Errors; D006349:Heart Valve Diseases / Q000209:etiology* / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D012008:Recurrence; D013927:Thrombosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy
D017153:Antibodies, Anticardiolipin; D007074:Immunoglobulin G