Waist-hip ratio and breast cancer risk in urbanized Nigerian women.
BACKGROUND
The aim of this study was to examine the relationship between waist-hip ratio and the risk of breast cancer in an urban Nigerian population.


METHODS
Between March 1998 and August 2000, we conducted a case-control study of hospital-based breast cancer patients (n = 234) and population-based controls (n = 273) using nurse interviewers in urban Southwestern Nigeria.


RESULTS
Multivariable logistic regression showed a significant association between the highest tertile of waist-hip ratio and the risk of breast cancer (odds ratio= 2.67, 95% confidence interval = 1.05-6.80) among postmenopausal women. No association was found in premenopausal women.


CONCLUSIONS
The present study, the first in an indigenous African population, supports other studies that have shown a positive association between obesity and breast cancer risk among postmenopausal women.
Adebamowo
Clement A
CA
Division of Oncology, Department of Surgery, University College Hospital, Ibadan, Nigeria. clement.adebamowo@+channing.harvard.edu
Ogundiran
Temidayo O
TO
Adenipekun
Adeniyi A
AA
Oyesegun
Rasheed A
RA
Campbell
Oladapo B
OB
Akang
Effiong E
EE
Rotimi
Charles N
CN
Olopade
Olunfunmilayo I
OI
D000293:Adolescent; D000328:Adult; D001824:Body Constitution / Q000502:physiology*; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000503:physiopathology*; D016022:Case-Control Studies; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D015999:Multivariate Analysis; D009549:Nigeria; D017698:Postmenopause; D017697:Premenopause; D012307:Risk Factors; D014504:Urban Health; D014505:Urban Population