[Genetic tests for leukemia].
The diagnosis of leukemia is mainly based on chromosome analysis and genetic testing. The analysis of molecular genetics associated with chromosome abnormalities has contributed to new classifications of leukemia. The minimal residual disease(MRD) in its currently accepted application refers to low-level disease detected by quantitative PCR techniques in clinical situations. It is anticipated that efforts in characterization of molecular genetics in leukemia will ultimately translate into better clinical outcomes for patients.
Kitamura
Kiyoshi
K
International Research Center for Medical Education, University of Tokyo.
D002869:Chromosome Aberrations; D006801:Humans; D007938:Leukemia / Q000175:diagnosis* / Q000235:genetics; D025202:Molecular Diagnostic Techniques; D018365:Neoplasm, Residual / Q000175:diagnosis; D016133:Polymerase Chain Reaction; D014178:Translocation, Genetic