title: Heterogeneous Epstein-Barr virus latent gene expression in AIDS-associated lymphomas and in type I Burkitt's lymphoma cell lines.
abstract: Epstein-Barr virus (EBV) is associated with lymphoma in immunocompromised patients. This study provides evidence that the expression of EBV nuclear antigen-3 genes can be directed from the F promoter in different type I Burkitt's lymphoma cell lines and in some lymphomas from human immunodeficiency virus-infected patients. This expression occurs predominantly after induction of the EBV lytic cycle.
authors.affiliation: INSERM EPI 03-34, IUH, Hôpital Saint-Louis, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Touitou
authors.affiliation: INSERM EPI 03-34, IUH, Hôpital Saint-Louis, Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Arbach
authors.affiliation: INSERM EPI 03-34, IUH, Hôpital Saint-Louis, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Cochet
authors.affiliation: Hématologie Biologique, Hôpital Avicenne, EA 1625, UFR SMBH, Université Paris 13 Bobigny, France.
authors.forename: J
authors.initials: J
authors.lastname: Feuillard
authors.affiliation: Hématologie Biologique, Hôpital Avicenne, EA 1625, UFR SMBH, Université Paris 13 Bobigny, France.
authors.forename: A
authors.initials: A
authors.lastname: Martin
authors.affiliation: Hématologie Biologique, Hôpital Avicenne, EA 1625, UFR SMBH, Université Paris 13 Bobigny, France.
authors.forename: M
authors.initials: M
authors.lastname: Raphaël
authors.affiliation: INSERM EPI 03-34, IUH, Hôpital Saint-Louis, Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Joab
mesh_terms: D001483:Base Sequence; D002051:Burkitt Lymphoma / Q000821:virology*; D002460:Cell Line; D004279:DNA, Viral / Q000235:genetics; D019309:Epstein-Barr Virus Nuclear Antigens / Q000032:analysis / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000502:physiology*; D006801:Humans; D007150:Immunohistochemistry; D016483:Lymphoma, AIDS-Related / Q000821:virology*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017735:Virus Latency
chemical_list: D004279:DNA, Viral; C422762:EBNA-3B antigen; D019309:Epstein-Barr Virus Nuclear Antigens; D012333:RNA, Messenger