title: Nodular secondary syphilis.
abstract: Secondary syphilis can have protean clinical manifestations and may present with unusual lesions, which may go unrecognized. We report a case of secondary syphilis with nodular lesions. A 22 year old male presented with nodular and annular skin lesions over the face, back and limbs and condylomata lata lesion at the penoscrotal junction associated with generalized lymphadenopathy, fever and malaise. Prior to onset of these lesions the patient also had history of a painless genital sore, which healed within two weeks. The serology revealed a reactive VDRL(1:64) and positive TPHA. The HIV serology was non-reactive. The patient responded to a single dose of benzathine penicillin, 2.4 million units, given intramuscularly. This case highlights that secondary syphilis may present with nodular lesions and should be suspected in the appropriate clinical setting.
authors.affiliation: Department of Dermatology and STD, JIPMER, Pondicherry-605 006, India.
authors.forename: Shriya
authors.initials: S
authors.lastname: Dave
authors.forename: Deepthy V
authors.initials: DV
authors.lastname: Gopinath
authors.forename: Devinder M M
authors.initials: DM
authors.lastname: Thappa
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D009055:Mouth / Q000473:pathology; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D010413:Penis / Q000473:pathology; D013587:Syphilis / Q000175:diagnosis* / Q000188:drug therapy; D013588:Syphilis Serodiagnosis; D013591:Syphilis, Cutaneous / Q000175:diagnosis; D014210:Treponema pallidum / Q000302:isolation & purification
chemical_list: D010401:Penicillin G Benzathine