Phospholipid/cholesterol model membranes: formation of cholesterol crystallites.
Experimental data that define conditions under which cholesterol crystallites form in cholesterol/phospholipid model membranes are reviewed. Structural features of the phospholipids that determine cholesterol crystallization include the length and degree of unsaturation of the acyl chains, the presence of charge on the headgroups and interheadgroup hydrogen bonds.
Bach
Diana
D
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, 76100, Israel. bmbach@wicc.weizmann.ac.il
Wachtel
Ellen
E
D002152:Calorimetry, Differential Scanning; D002784:Cholesterol / Q000737:chemistry*; D003460:Crystallization; D006860:Hydrogen Bonding; D008051:Lipid Bilayers / Q000737:chemistry*; D015394:Molecular Structure; D010743:Phospholipids / Q000737:chemistry*; D012995:Solubility; D013696:Temperature; D014961:X-Ray Diffraction
D008051:Lipid Bilayers; D010743:Phospholipids; D002784:Cholesterol