title: Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel.
abstract: On return from duty in North Solomons Province (including Bougainville Island), Papua New Guinea, 586 Australian Defence Force personnel received either primaquine (14-d) or tafenoquine (3-d) post-exposure malaria prophylaxis. Within 12 months, 6 of the 214 volunteers receiving primaquine and 7 of 378 receiving tafenoquine had developed vivax malaria. Overall, volunteers preferred the shorter course of tafenoquine.
authors.affiliation: Australian Defence Force Combined Health Element, Loloho, North Solomons Province, Papua New Guinea.
authors.forename: Peter
authors.initials: P
authors.lastname: Nasveld
authors.forename: Scott
authors.initials: S
authors.lastname: Kitchener
authors.forename: Michael
authors.initials: M
authors.lastname: Edstein
authors.forename: Karl
authors.initials: K
authors.lastname: Rieckmann
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000962:Antimalarials / Q000627:therapeutic use*; D001315:Australia; D005260:Female; D006801:Humans; D016780:Malaria, Vivax / Q000517:prevention & control*; D008297:Male; D008889:Military Personnel; D018512:Parasitemia / Q000517:prevention & control; D011319:Primaquine / Q000627:therapeutic use*
chemical_list: D000634:Aminoquinolines; D000962:Antimalarials; C055852:tafenoquine; D011319:Primaquine