Using temperature gradient gas chromatography to determine or predict vapor pressures and linear solvation energy relationship parameters of highly boiling organic compounds.
An isothermal chromatographic method allowing determination of sigmabetaH2 and sigmaalphaH2 descriptors of the linear solvation energy relationship (LSER) was tested and results obtained are presented. This method is based on the use of four stationary phases of various polarity. On the other hand, it was demonstrated that the temperature gradient chromatography may be successfully used to determine LSER descriptors. Results of piH2, sigmabetaH2 and log L16 determination are reported. This approach opens new possibilities of precise and rapid determination of LSER descriptors of high boiling compounds using a small number of phases. It was demonstrated that the log L16 descriptor may be used to estimate vapor pressures of high boiling organic compounds with a better accuracy than those usually obtained with chromatographic methods.
Mutelet
F
F
Laboratoire de Thermodynamique des Milieux Polyphasés, Ecole Nationale Supérieure des Industries Chimiques, Institut National Polytechnique de Lorraine, 1 Rue Grandville, BP 451, F-54001 Nancy Cedex, France.
Rogalski
M
M
D002849:Chromatography, Gas / Q000379:methods*; D009930:Organic Chemicals / Q000737:chemistry*; D011312:Pressure; D015203:Reproducibility of Results; D013696:Temperature
D009930:Organic Chemicals