Aging, immunity, and tumor susceptibility.
The study of aging, susceptibility to tumors, and immunity is at an initial stage, and numerous excellent questions challenge immunologists and tumor biologists. Because unpredicted factors contribute to tumor susceptbility in the human population, the authors feel that the development of an animal model is essential to dissect these complicated issues.
Zhang
Huang-Ge
HG
The University of Alabama at Birmingham, Department of Medicine, Division of Clinical Immunology and Rheumatology, Lyons-Harrison Research Building, Room 473, 701 South 19th Street, Birmingham, AL 35294, USA.
Grizzle
William E
WE
D017668:Age of Onset; D000368:Aged; D000375:Aging / Q000276:immunology*; D000818:Animals; D020022:Genetic Predisposition to Disease; D006801:Humans; D007113:Immunity, Innate; D009369:Neoplasms / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology