Preparation of N-aryl azacrown ether derivatives, using arene-iron chemistry.
m- or p-phenylenediamine and m- or p-chlorophenyl-substituted azacrown ether derivatives were synthesized through sequential nucleophilic substitution of [(eta(5)-cyclopentadienyl)(eta(6)-(m- or p-dichlorobenzene))]iron hexafluorophosphate by azacrown ethers and cyclohexaamines. Monoarylation is the main reaction for diazacrown ethers. The overall yield from the starting complex is 50-96% for multiple steps.
Pearson
Anthony J
AJ
Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA. ajp4@po.cwru.edu
Xiao
Wenjing
W