Lipopolysaccharide down-regulates leukotriene C4 synthase gene expression in a cell-specific manner in the monocyte-like cell line, THP-1.
Serio
Kenneth J
KJ
Department of Medicine, Veterans Affairs San Diego Healthcare System and the University of California, San Diego, CA 92161, USA.
Johns
Scott C
SC
Luo
Linda
L
Hodulik
Craig R
CR
Bigby
Timothy D
TD
D001249:Asthma / Q000201:enzymology / Q000235:genetics*; D002460:Cell Line; D015536:Down-Regulation / Q000187:drug effects*; D015870:Gene Expression / Q000187:drug effects* / Q000235:genetics*; D005982:Glutathione Transferase / Q000187:drug effects* / Q000235:genetics*; D006801:Humans; D066298:In Vitro Techniques; D008070:Lipopolysaccharides / Q000494:pharmacology*; D009000:Monocytes / Q000187:drug effects* / Q000201:enzymology
D008070:Lipopolysaccharides; D005982:Glutathione Transferase; C041116:leukotriene-C4 synthase