Neurologic complications associated with influenza vaccination: two adult cases.
We describe two adult cases of neurologic complications occurring after influenza vaccination. The first case was a 62-year-old man who experienced convulsions 5 days after vaccination, and the second case was a 70-year-old man who exhibited paraplegia 7 days after vaccination. Diagnoses of acute disseminated encephalomyelitis and transverse myelitis with acute motor axonal neuropathy were made, respectively, and steroid pulse therapy and intravenous gamma globulin therapy alleviated the patients' symptoms. Although the efficacy and cost benefit of influenza vaccination have been widely accepted, such neurologic complications might occur in the elderly or even in adults.
Nakamura
Naoko
N
Department of Neurology, Fujita Health University, School of Medicine, Toyoake, Aichi.
Nokura
Kazuya
K
Zettsu
Takaaki
T
Koga
Hiroshi
H
Tachi
Masayuki
M
Terada
Masaki
M
Katoh
Hideshi
H
Itoh
Yuri
Y
Osawa
Hiroyuki
H
Ozeki
Toshihiko
T
Yamamoto
Hiroko
H
D000367:Age Factors; D000368:Aged; D004673:Encephalomyelitis, Acute Disseminated / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control*; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D020551:Pulse Therapy, Drug; D018570:Risk Assessment; D016896:Treatment Outcome; D014611:Vaccination / Q000009:adverse effects
D016756:Immunoglobulins, Intravenous; D007252:Influenza Vaccines; D008775:Methylprednisolone