Hemopericardium and cardiac tamponade as presenting findings of dexamethasone-induced hypertrophic cardiomyopathy complicated by transmural myocardial infarction.
This is the first report of dexamethasone-induced left ventricular outflow obstruction causing decreased coronary artery perfusion and apical transmural cardiac infarct that resulted in hemopericardium and rapid cardiac tamponade. The differential diagnosis of hemorrhagic pericardial effusion must now include dexamethasone-induced hypertrophic cardiomyopathy.
Lilien
L D
LD
Neonatology Associates, 300 W. Clarendon, No. 375, Phoenix, AZ 85013, USA.
Lilien
R H
RH
Setrakian
S
S
D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D002305:Cardiac Tamponade / Q000209:etiology*; D002312:Cardiomyopathy, Hypertrophic / Q000139:chemically induced*; D003326:Coronary Circulation / Q000502:physiology; D003907:Dexamethasone / Q000009:adverse effects*; D004200:Diseases in Twins; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology*; D010490:Pericardial Effusion / Q000209:etiology*; D014694:Ventricular Outflow Obstruction / Q000139:chemically induced*
D000893:Anti-Inflammatory Agents; D003907:Dexamethasone