title: Allele frequencies for an interferon-gamma microsatellite in a population of Brazilian leprosy patients.
abstract: A group of Brazilian leprosy patients and controls were genotyped for a CA-repeat microsatellite polymorphism within the interferon (IFN)-gamma gene. A significantly higher frequency of alleles 5-7 was observed in this patient population, indicating that IFN-gamma gene polymorphism may contribute to the course of leprosy post-infection.
authors.affiliation: Department of Histocompatability & Immunogenetics, National Blood Dervice, London, UK.
authors.forename: M P
authors.initials: MP
authors.lastname: Reynard
authors.forename: D
authors.initials: D
authors.lastname: Turner
authors.forename: A P
authors.initials: AP
authors.lastname: Junqueira-Kipnis
authors.forename: M
authors.initials: M
authors.lastname: Ramos de Souza
authors.forename: C
authors.initials: C
authors.lastname: Moreno
authors.forename: C V
authors.initials: CV
authors.lastname: Navarrete
mesh_terms: D001938:Brazil; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006801:Humans; D007371:Interferon-gamma / Q000235:genetics*; D007918:Leprosy / Q000235:genetics*; D018895:Microsatellite Repeats; D009010:Monte Carlo Method
chemical_list: D007371:Interferon-gamma