title: [Neovir therapy in acute hepatitis C].
abstract: Neovir, an inductor of interferon-alpha, was injected intramuscularly to 15 male patients aged 16-44 years with diagnosed acute viral hepatitis in a dose of 250 mg a day, 2-3 times a week, for 3 months. By the end of the therapy hepatitis C virus RNA could still be isolated in 84.6% of the patients; the values of AlaT, AsaT and alkaline phosphatase exceeded the normal levels twofold. The result of the therapy is regarded as ineffective.
authors.affiliation: State Medical Stomatology University, State Clinical Infectious Hospital No. 2, Central Research Institute of Epidemiology, Moscow, Russia.
authors.forename: S L
authors.initials: SL
authors.lastname: Maksimov
authors.forename: N D
authors.initials: ND
authors.lastname: Iushchuk
authors.forename: I M
authors.initials: IM
authors.lastname: Roslyĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Kravchenko
authors.forename: T V
authors.initials: TV
authors.lastname: Danilova
mesh_terms: D000166:Acridines / Q000627:therapeutic use*; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D015415:Biomarkers / Q000097:blood; D004334:Drug Administration Schedule; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000097:blood / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D007273:Injections, Intramuscular; D007369:Interferon Inducers / Q000627:therapeutic use*; D008297:Male; D012367:RNA, Viral / Q000032:analysis; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D000166:Acridines; D015415:Biomarkers; D007369:Interferon Inducers; D012367:RNA, Viral; C077681:Camedon; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase