Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma.
Ingram
Jennifer L
JL
Laboratory of Pulmonary Pathobiology (Drs. Ingram and Bonner, Ms. Rice, and Ms. Geisenhoffer), National Institute of Environmental Health Science, Research Triangle Park, NC 27709, USA.
Rice
Annette
A
Geisenhoffer
Kristen
K
Madtes
David K
DK
Bonner
James C
JC
D000818:Animals; D001249:Asthma / Q000150:complications* / Q000503:physiopathology; D002468:Cell Physiological Phenomena / Q000187:drug effects*; D004195:Disease Models, Animal; D005347:Fibroblasts / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D018793:Interleukin-13 / Q000494:pharmacology*; D008168:Lung / Q000187:drug effects* / Q000503:physiopathology; D009210:Myofibrils / Q000187:drug effects* / Q000502:physiology; D011658:Pulmonary Fibrosis / Q000209:etiology* / Q000503:physiopathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D015533:Transcriptional Activation / Q000187:drug effects* / Q000502:physiology
D018793:Interleukin-13