Neurological complications of rabies vaccines.
The rabies vaccines containing neural elements are used in some countries including India. We report three cases that presented with various neurological complications following the use of these vaccines. The presenting manifestations included those of encephalitis, radiculitis and acute inflammatory demyelinating polyradiculoneuropathy. These neurological complications are highlighted so that scientific evidence compels the community to discontinue the use of the neural tissue rabies vaccines. Newer generation cell culture rabies vaccines should be preferred over the neural tissue rabies vaccines for post-exposure prophylaxis.
Tullu
Millind S
MS
Departments of Pediatrics and Radiology, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai 400 012, Maharashtra, India. millindtullu@yahoo.com
Rodrigues
Sean
S
Muranjan
Mamta N
MN
Bavdekar
Sandeep B
SB
Kamat
Jaishree R
JR
Hira
Priya R
PR
D002552:Cerebral Ventricles / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003711:Demyelinating Diseases / Q000139:chemically induced*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011819:Rabies Vaccines / Q000009:adverse effects*
D011819:Rabies Vaccines