Morpho-functional adaptations in the bone tissue under the space flight conditions.
Microgravity in space flight--situation of a maximum deficit of supporting loading on the skeleton and good model for finding-out of osteopenia and osteoporosis development laws, which are wide-spreading now and are "civilization diseases". Most typical for bones in conditions of a microgravitation by changes are: a decrease of intensity growth and osteoplastic processes, osteopenia and osteoporosis, decreasing of a mechanical strength and the risk of breaches arising (Oganov V.S., Schneider V. (1996)). Cytological mechanisms of gravity-dependent reactions in a bone tissue remain in many respects not-clear. By the purpose of our work was the analysis of some ultrastructural changes in bone tissue cells of the monkeys (Macaca mulatta), staying during two weeks onboard the biosatellite BION -11.
Rodionova
N V
NV
Schmalhausen Institute of Zoology, NAS of Ukraine, Kiev, Ukraine. rodionova@iz.freenet.kiev.ua
Oganov
V S
VS
D000222:Adaptation, Physiological; D000818:Animals; D004721:Endoplasmic Reticulum / Q000502:physiology; D006056:Golgi Apparatus / Q000502:physiology; D007085:Ilium / Q000502:physiology* / Q000648:ultrastructure; D008253:Macaca mulatta; D008928:Mitochondria / Q000502:physiology; D015388:Organelles / Q000502:physiology; D010006:Osteoblasts / Q000648:ultrastructure*; D010011:Osteocytes / Q000648:ultrastructure*; D013026:Space Flight; D014893:Weightlessness