Acute-onset autoimmune hepatitis treated with living donor-liver transplantation.
A 50-year-old woman was diagnosed with acute-onset autoimmune hepatitis. She did not respond to steroid therapy including pulse therapy, and was subsequently treated with living donor-liver transplantation 36 days after the beginning of steroid therapy. Except for a period of transient mild acute rejection, her liver function tests remained within a normal range for 2.5 years after the operation. The courses of autoimmune hepatitis patients treated with living-donor liver transplantation have not been previously documented to our knowledge. Living donor-liver transplantation is thought to be one of the therapy options for severe autoimmune hepatitis.
Kawai
Keiko
K
Third Department of Internal Medicine, Ehime University School of Medicine, Onsen-gun.
Michitaka
Kojiro
K
Miyauchi
Shozo
S
Sano
Masahiro
M
Abe
Masanori
M
Ninomiya
Tsuneyuki
T
Matsuura
Bunzo
B
Masumoto
Toshikazu
T
Akbar
S M Fazle
SM
Horiike
Norio
N
Onji
Morikazu
M
D000208:Acute Disease; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D019693:Hepatitis, Autoimmune / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D007564:Japan; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008875:Middle Aged; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome