Posttransplant CD30+ (Ki-1) anaplastic large cell lymphoma: a case report and review of the literature.
Posttransplant CD30(+) (Ki-1) anaplastic large cell lymphoma (ALCL) is rare. A review of the literature revealed only 3 such cases. All 3 cases were developed after single-organ transplantation. We describe CD30(+) (Ki-1) ALCL in a dual-organ (liver and heart) transplantation recipient. The patient was a 68-year-old white female who underwent an orthotopic heart transplantation in 1999 and a liver transplantation in 2000. She presented with nausea and was found to have CD30(+) (Ki-1) ALCL by pathologic examination of the gastric antrum biopsy specimen. To our knowledge, this patient represents the first reported case of posttransplant CD30(+) ALCL following a dual-organ transplantation.
Lee
Lisa Y
LY
Mount Sinai Medical Center, Department of Pathology, New York, NY 10029, USA.
Harpaz
Noam
N
Strauchen
James A
JA
D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology; D005260:Female; D016027:Heart Transplantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis*; D011706:Pyloric Antrum / Q000473:pathology