Second cancers in survivors of childhood cancer.
More than 70% of children diagnosed with cancer can now be expected to be long-term survivors. However, the consequences of 'cure' might be considerable for the survivors of cancer: 60-70% of young adults who have survived childhood cancer will develop at least one medical disability as a result of their cancer or, more commonly, as a result of their therapy. Of these, the most devastating is a second cancer.
Bhatia
Smita
S
City of Hope National Medical Center, Duarte, California 91010, USA.
Sklar
Charles
C
D000367:Age Factors; D064420:Drug-Related Side Effects and Adverse Reactions; D004777:Environment; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality / Q000532:radiotherapy; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D012307:Risk Factors; D013534:Survival; D013997:Time Factors