title: Advances in the pharmacological treatment of pathological gambling.
abstract: In the present paper we discuss the current status of drug treatment for pathological gambling and the scientific rationales underlying the various pharmacological approaches. Specifically, we summarize the treatment study results of serotonin reuptake inhibitors, mood stabilizers, opioid antagonists, and atypical antipsychotics in pathological gambling. We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation.
authors.affiliation: Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454-1495, USA. grant045@umn.edu
authors.forename: Jon E
authors.initials: JE
authors.lastname: Grant
authors.forename: Suck Won
authors.initials: SW
authors.lastname: Kim
authors.forename: Marc N
authors.initials: MN
authors.lastname: Potenza
mesh_terms: D018692:Antimanic Agents / Q000494:pharmacology; D016739:Behavior, Addictive / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005715:Gambling; D006801:Humans; D009292:Narcotic Antagonists / Q000494:pharmacology; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology
chemical_list: D018692:Antimanic Agents; D009292:Narcotic Antagonists; D017367:Selective Serotonin Reuptake Inhibitors