title: Efficacy of bovine viral diarrhea vaccine used in Japan against bovine viral diarrhea virus type 2 strain 890.
abstract: Bovine viral diarrhea virus (BVDV) has been segregated into two genotypes, type 1 and type 2. To determine the efficacy of the commercially available bovine viral diarrhea type 1 vaccine used in Japan against BVDV type 2, calves were infected with BVDV type 2 strain 890 4 weeks after administration of the vaccine. The vaccinated calves did not develop any clinical signs and hematological changes such as observed in unvaccinated calves after the challenge. Furthermore, the challenge virus was not recovered from the vaccinated calves throughout the duration of the experiment, whereas it was recovered from all unvaccinated calves. The bovine viral diarrhea vaccine used in Japan is efficacious against infection with BVDV type 2 strain 890.
authors.affiliation: National Veterinary Assay Laboratory, Tokyo, Japan.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Shimazaki
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Nakamura
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Taguchi
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Inoue
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis / Q000276:immunology; D001831:Body Temperature; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000276:immunology* / Q000517:prevention & control*; D002417:Cattle; D030242:Diarrhea Virus 2, Bovine Viral / Q000276:immunology*; D007564:Japan; D009500:Neutralization Tests; D013997:Time Factors; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines