[Angiotensin-converting enzyme, quinapril, in treating chronic cardiac failure].
OBJECTIVE
To assess effectiveness of ACE inhibitor quinapril in patients with moderate cardiac failure of ischemic etiology.


METHODS
20 patients received quinapril in a daily dose 20 mg for 6 months. Clinical condition, exercise tolerance, functional and geometric parameters of the left ventricle, Holter monitoring, heart rhythm variability, late potentials were studied before and after the treatment.


RESULTS
The treatment relieved symptoms significantly, exercise tolerance increased, positive changes occurred in systotic, diastotic functions and left ventricular geometry. Ischemic episodes, supraventricular extrasystoles reduced in number and duration.


CONCLUSIONS
Quinapril is an effective drug for treatment of moderate ischemic heart failure.
Gadzhiev
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AN
D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D008875:Middle Aged; D000077583:Quinapril; D044005:Tetrahydroisoquinolines; D016896:Treatment Outcome
D000806:Angiotensin-Converting Enzyme Inhibitors; D007546:Isoquinolines; D044005:Tetrahydroisoquinolines; D000077583:Quinapril