title: Chronic myeloid leukaemia at the Kenyatta National Hospital, Nairobi.
abstract: OBJECTIVE
  To determine the clinical and haematological factors associated with treatment and outcome of chronic myeloid leukaemia (CML) at Kenyatta National Hospital.
  
  
  METHODS
  Retrospective survey of patients treated for chronic myeloid leukaemia.
  
  
  METHODS
  Kenyatta National hospital, Nairobi, Kenya, between April 1990 and August 2000.
  
  
  METHODS
  Patients with chronic myeloid leukaemia.
  
  
  RESULTS
  One hundred and four patients, 55 males and 49 females, age range 10-72 years with a median age of 35 years. Treatment with busulphan getting less popular in favour of hydroxyurea. Median follow-up 20 months with none of the clinical and haematological parameters impacting significantly on duration of follow-up.
  
  
  CONCLUSIONS
  CML occurs at a younger age-group in Kenya, and none of the clinical or haematological parameters appears to impact on follow-up duration.
authors.affiliation: Department of Medicine, Faculty of Medicine, College of Health Sciences, University of Nairobi, PO Box 19676, Nairobi, Kenya.
authors.forename: N A
authors.initials: NA
authors.lastname: Othieno-Abinya
authors.forename: L O
authors.initials: LO
authors.lastname: Nyabola
authors.forename: G W
authors.initials: GW
authors.lastname: Kiarie
authors.forename: R
authors.initials: R
authors.lastname: Ndege
authors.forename: J M D
authors.initials: JM
authors.lastname: Maina
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002066:Busulfan / Q000008:administration & dosage; D002648:Child; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D007630:Kenya; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013163:Splenomegaly / Q000145:classification / Q000209:etiology; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D018906:Antineoplastic Agents, Alkylating; D002066:Busulfan; D006918:Hydroxyurea