[Efficacy and tolerance assessment of mitrazapine in the treatment of depression in the elderly--preliminary report].
Depressive disorders are often met in the elderly, its course is usually protracted and outcome sometimes fatal. The purpose of this study is evaluation of efficacy and tolerance of mirtazapine in this group of patients. 24 patients (mean age 73.8) with major depressive episode (> 20 in 17-tem HAMD; also CGI scale was used for evaluation) without psychotic features were treated with mirtazapine (30-45 mg) for 6 months.


RESULTS
Improvement (especially such symptoms as better mood and sleep, less anxiety) could be seen in 75% of patients.
Florkowski
Antoni
A
Katedra i Klinika Psychiatrii Wojskowej Akademii Medycznej w Łodzi.
Gruszczyński
Wojciech
W
Zboralski
Krzysztof
K
D000368:Aged; D000369:Aged, 80 and over; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage* / Q000009:adverse effects; D003866:Depressive Disorder / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D015577:Geriatric Assessment; D006801:Humans; D008803:Mianserin / Q000008:administration & dosage* / Q000009:adverse effects / Q000031:analogs & derivatives; D000078785:Mirtazapine; D013997:Time Factors; D016896:Treatment Outcome
D000929:Antidepressive Agents, Tricyclic; D008803:Mianserin; D000078785:Mirtazapine