Pericardiocentesis and pancreatic aspiration needle biopsy in coagulopathic and thrombocytopenic cirrhotic patient.
We report on the case of a 40-year-old patient with coagulopathic alcoholic cirrhosis who underwent ultrasound-directed pericardiocentesis and fine-needle aspiration biopsy of the pancreas after receiving recombinant human factor VIIa (rhFVIIa). The infusion of rhFVIIa rapidly corrected her coagulopathy and made it possible to perform both procedures. The marked changes produced in the prothrombin time and international normalized ratio as a result of the infusion of rhFVIIa are presented. As a result of these changes in coagulation status, both procedures were performed safely, and the patient's clinical management and subsequent care plan were defined.
Mindikoglu
Ayse L
AL
Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA.
Anantharaju
Abhinandana
A
Villanueva
Jaime
J
Shah
Nikunj
N
Van Thiel
David H
DH
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D001778:Blood Coagulation Disorders / Q000209:etiology*; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications*; D010190:Pancreatic Neoplasms / Q000473:pathology; D020519:Pericardiocentesis / Q000379:methods*; D011994:Recombinant Proteins / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000209:etiology
D011994:Recombinant Proteins; D015942:Factor VIIa