Acetaminophen toxicosis in a Dalmatian.
An 11-year-old, spayed female Dalmatian was presented with suspected acetaminophen toxicosis. The dog was severely depressed. Methemoglobinemia, facial edema, and hemoglobinuria responded to treatment with intravenous fluids, N-acetylcysteine, ascorbic acid, and sodium bicarbonate. There was no clinical evidence of hepatic damage typical of acetaminophen toxicity in the dog.
MacNaughton
Sarah M
SM
Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
D000082:Acetaminophen / Q000506:poisoning*; D000111:Acetylcysteine / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D000818:Animals; D001205:Ascorbic Acid / Q000627:therapeutic use; D004283:Dog Diseases / Q000139:chemically induced* / Q000628:therapy; D004285:Dogs; D004638:Emergency Treatment / Q000662:veterinary; D005260:Female; D005440:Fluid Therapy / Q000662:veterinary; D016166:Free Radical Scavengers / Q000627:therapeutic use; D008099:Liver / Q000187:drug effects / Q000473:pathology; D008708:Methemoglobinemia / Q000139:chemically induced / Q000662:veterinary; D017693:Sodium Bicarbonate / Q000627:therapeutic use; D016896:Treatment Outcome
D018712:Analgesics, Non-Narcotic; D016166:Free Radical Scavengers; D000082:Acetaminophen; D017693:Sodium Bicarbonate; D001205:Ascorbic Acid; D000111:Acetylcysteine