title: [Epidemiological and immunological monitoring of tetanus in Georgia (Republic)].
abstract: During the period of 1961-1990 the regular immunological and epidemiological monitoring of tetanus was carried out. At the prevaccination period (1937-1960) 140 cases of tetanus were registered, 77 patients died (morbidity rate being 0.97-0.11 per 100,000 of the population with mortality rate equal to 55.6%). At the period of mass vaccinal prophylaxis (1960-1990) 56 cases were registered and 27 patients died (the corresponding values: 0.09-0.11 with 48.2% mortality). In 1981-1990 altogether 53,213 vaccinees were examined. 4,864 vaccinees (8.9%) proved to be seronegative and 43,615 vaccinees (81.9%) were found to have protective antibody titers. 4,220 pregnant women were examined; 476 women (11.2%) proved to be seronegative and 3,576 women (84.3%) were found to have protective antibody titers. Timely specific prophylaxis proved to be the only way for decreasing tetanus morbidity.
authors.affiliation: State Medical Academy of Post-Diploma Medical Training, Tbilisi, Georgia.
authors.forename: V A
authors.initials: VA
authors.lastname: Kurashvili
authors.forename: I Sh
authors.initials: ISh
authors.lastname: Dgebuadze
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003017:Clostridium tetani / Q000276:immunology*; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D005846:Georgia (Republic) / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000276:immunology; D012042:Registries; D016036:Seroepidemiologic Studies; D013742:Tetanus / Q000453:epidemiology* / Q000276:immunology* / Q000517:prevention & control; D013745:Tetanus Toxoid / Q000008:administration & dosage; D014611:Vaccination
chemical_list: D000907:Antibodies, Bacterial; D013745:Tetanus Toxoid