Reflections on a century of protein chemistry.
The development of protein structural chemistry during the twentieth century is briefly reviewed. Emphasis is placed on certain major problems that have defined the field, and how they have been resolved, often as a consequence of technological advances. The ways in which incorrect hypotheses have affected the development of the field are also discussed.
van Holde
K E
KE
Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331-7305, USA. vanholdk@ucs.orst.edu
D001671:Biochemistry / Q000266:history; D018360:Crystallography, X-Ray / Q000266:history; D049673:History, 20th Century; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000266:history*
D011506:Proteins