Cardiovascular risk factors in diabetic patients with hypertension.
Individuals with diabetes mellitus have cardiovascular disease (CVD) mortality comparable to nondiabetics who have suffered a myocardial infarction or stroke. Aggressive management of risk factors such as hypertension, dyslipidemia, and platelet dysfunction in persons with diabetes has been shown to reduce morbidity and mortality in prospective randomized controlled clinical trials. Accordingly, there are national mandates to lower blood pressure to less than 130/85 mm Hg, reduce low-density lipoprotein cholesterol to less than 100 mg/dL, and institute aspirin therapy in adult patients with diabetes. Although not definitively shown to reduce CVD, there are also recommendations to control the level of glycemia, as well. This article discusses CVD risk factors in the diabetic patient with hypertension.
Winer
Nathaniel
N
Department of Medicine, SUNY Health Science Center, 450 Clarkson Avenue, Box 1205, Brooklyn, NY 11203, USA.
Sowers
James R
JR
D002318:Cardiovascular Diseases / Q000209:etiology*; D003925:Diabetic Angiopathies / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D012307:Risk Factors