title: The role of interleukin-6 in nociception and pain.
abstract: That IL-6 is an interesting target in the study of pain is underscored by its biomolecular properties, its localization after experimental pain, and its modulating effect on pain after administration.
authors.affiliation: *Department of Anesthesia, Intensive Care, and Emergency Care and the Multidisciplinary Pain Centre, Ziekenhuis Oost Limburg, Genk, Belgium; †Johnson & Johnson, Pharmaceutical Research and Development, Beerse, Belgium; and ‡Department of Anesthesia, University Hospital of Nijmegen, Nijmegen, The Netherlands.
authors.forename: Raf F
authors.initials: RF
authors.lastname: De Jongh
authors.forename: Kris C
authors.initials: KC
authors.lastname: Vissers
authors.forename: Theo F
authors.initials: TF
authors.lastname: Meert
authors.forename: Leo H D J
authors.initials: LHDJ
authors.lastname: Booij
authors.forename: Catharina S
authors.initials: CS
authors.lastname: De Deyne
authors.forename: René J
authors.initials: RJ
authors.lastname: Heylen
mesh_terms: D000818:Animals; D006801:Humans; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology; D018836:Inflammation Mediators / Q000378:metabolism / Q000502:physiology*; D015850:Interleukin-6 / Q000378:metabolism / Q000502:physiology*; D009474:Neurons / Q000187:drug effects; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology*; D010146:Pain / Q000378:metabolism / Q000503:physiopathology*
chemical_list: D018836:Inflammation Mediators; D015850:Interleukin-6