title: Metastatic renal cell carcinoma to the ovary: a case report and discussion of differential diagnoses.
abstract: The clinical presentation of renal cell carcinoma in the ovary is rare and may closely resemble that of other ovarian clear cell tumors. Metastatic renal cell carcinoma was diagnosed in a patient who presented with a right adnexal mass and no other significant past medical history. The gross appearance of the tumor suggested a primary ovarian neoplasm. However, microscopic and immunohistochemical analysis revealed involvement of both ovaries by a clear cell tumor with features of renal cell carcinoma. A renal mass was subsequently discovered. We discuss the clinical, histologic, and immunohistochemical features of this tumor and the features of other clear cell neoplasms in the differential diagnosis.
authors.affiliation: Department of Pathology, University of Miami/Jackson Memorial Medical Center, FL 33136, USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: Hammock
authors.forename: Zeina
authors.initials: Z
authors.lastname: Ghorab
authors.forename: Carmen R
authors.initials: CR
authors.lastname: Gomez-Fernandez
mesh_terms: D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000175:diagnosis