title: Diagnostic value of maximum intensity projections versus source images for assessment of contrast-enhanced three-dimensional breath-hold magnetic resonance coronary angiography.
abstract: OBJECTIVE
  We compared maximum intensity projections (MIP) versus original source images (SI) in respect to detection of coronary artery stenoses by means of magnetic resonance (MR) coronary angiography.
  
  
  METHODS
  MR coronary angiography was performed on 61 patients. MIP and SI were independently evaluated as to presence of significant stenoses in the proximal and midcoronary segments and compared with x-ray angiography.
  
  
  RESULTS
  A total of 315 of 427 (74%) coronary artery segments could be evaluated in MIP and 328 of 427 (77%) in SI. In segments able to be evaluated, MIP images demonstrated 84% (54/64) sensitivity and 87% (219/251) specificity, whereas SI images showed 85% (58/68) sensitivity and 90% (235/260) specificity. Overall accuracy was 87% (273/310) for MIP and 89% (293/328) for SI. There was no statistically significant difference between both modalities.
  
  
  CONCLUSIONS
  The MIP reconstructions showed comparable accuracy to unprocessed SI. However, MIP postprocessing is compromised by a higher number of images that were unable to be evaluated due to overlap of coronary arteries with adjacent cardiac structures.
authors.affiliation: Department of Internal Medicine II, Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Ulmenweg 18, 91054 Erlangen, Germany. dres.regenfus@t-online.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Regenfus
authors.forename: Dieter
authors.initials: D
authors.lastname: Ropers
authors.forename: Stephan
authors.initials: S
authors.lastname: Achenbach
authors.forename: Christian
authors.initials: C
authors.lastname: Schlundt
authors.forename: Winfried
authors.initials: W
authors.lastname: Kessler
authors.forename: Gerhard
authors.initials: G
authors.lastname: Laub
authors.forename: Werner
authors.initials: W
authors.lastname: Moshage
authors.forename: Werner G
authors.initials: WG
authors.lastname: Daniel
mesh_terms: D000465:Algorithms; D003287:Contrast Media; D023921:Coronary Stenosis / Q000175:diagnosis*; D003331:Coronary Vessels / Q000473:pathology*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA