[A review of the research progress on LIM protein family].
LIM Proteins contain one or more LIM domains. Proteins of this family capable of interacting with many types of proteins have been identified including structural protein, kinase, and several classes of transcription factors. These interactions have been discovered to display important roles in a variety of fundamental processes including transcriptional regulation, development of cell types and organization of the cytoskeleton. This article reviews recent advances in the characterization of members of the LIM protein family, their biology roles, LIM domain binding protein and the function in heart development.
Zheng
Bin
B
Department of Biochemistry, Institute of Basic Medicine, Hebei Medical University, Shijiazhuang 050017.
Wen
Jin-Kun
JK
Han
Mei
M
D000818:Animals; D002320:Cardiovascular Physiological Phenomena; D006333:Heart Failure / Q000503:physiopathology; D018398:Homeodomain Proteins / Q000145:classification* / Q000502:physiology*; D006801:Humans; D051379:Mice; D011487:Protein Conformation
D018398:Homeodomain Proteins