A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH.
In this paper we report 8-quinolineboronic acid as a novel type of fluorescent probe for carbohydrates. This boronic acid responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution.
Yang
Wenqian
W
Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA.
Yan
Jun
J
Springsteen
Greg
G
Deeter
Susan
S
Wang
Binghe
B
D001897:Boronic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*; D012996:Solutions
D001897:Boronic Acids; D002241:Carbohydrates; D005456:Fluorescent Dyes; D011804:Quinolines; D012996:Solutions; C477948:8-quinolineboronic acid