title: A manipulator system for 14-gauge large core breast biopsies inside a high-field whole-body MR scanner.
abstract: OBJECTIVE
  To investigate a robotic manipulator system for MR-guided breast biopsies inside a 1.5 T whole-body magnet.
  
  
  METHODS
  Fourteen patients with suspicious breast lesions (diameter 18.6 +/- 12 mm) underwent biopsy. Patients with malignant findings underwent surgery afterwards and the histologic findings between biopsy and surgery were correlated.
  
  
  RESULTS
  In five patients biopsy findings were histopathologically confirmed following open surgery. One tubular carcinoma was missed; one invasive cancer was underestimated. Seven patients with benign findings are still in the follow-up period.
  
  
  CONCLUSIONS
  The study demonstrates the feasibility to perform breast biopsies inside the magnet of a whole-body MR scanner by using a manipulator system.
authors.affiliation: Institute of Diagnostic and Interventional Radiology, Friedrich-Schiller-University Jena, Jena, Germany. stefan.pfleiderer@med.uni-jena.de
authors.forename: Stefan O R
authors.initials: SO
authors.lastname: Pfleiderer
authors.forename: Jürgen R
authors.initials: JR
authors.lastname: Reichenbach
authors.forename: Tarek
authors.initials: T
authors.lastname: Azhari
authors.forename: Christiane
authors.initials: C
authors.lastname: Marx
authors.forename: Ansgar
authors.initials: A
authors.lastname: Malich
authors.forename: Achim
authors.initials: A
authors.lastname: Schneider
authors.forename: Jörg
authors.initials: J
authors.lastname: Vagner
authors.forename: Harald
authors.initials: H
authors.lastname: Fischer
authors.forename: Werner A
authors.initials: WA
authors.lastname: Kaiser
mesh_terms: D001706:Biopsy / Q000295:instrumentation*; D001941:Breast Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004867:Equipment Design; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011446:Prospective Studies; D012371:Robotics