[Case-control study of hepatitis C HBs Ag and antivirus antibodies in chronic hepatopathies].
The aim of this study is to establish the prevalence of hepatitis C HBs Ag and of anti-virus antibodies in chronic hepatopathies. The prospective case-control study was carried out on 91 patients who needed to be treated for chronic hepatopathies and 92 occasional blood donors. The search for hepatitis C HBs Ag and anti-virus antibodies was done using third generation ELISA screening. At the end of the study, HBs Ag was found in 54% of the patients vs. 4.3% of the control (p=0.0006). The two markers were present more frequently in cirrhosis than in hepatocellular carcinoma (HCC) and their association was more frequent in the case of cirrhosis. In Mali, hepatitis B and C viruses play an important part in chronic hepatopathies.
Maiga
Moussa Y
MY
Service d'hépatogastroentérologie, Hôpital Gabriel-Touré, Bamako, Mali.
Dembele
Mamadou
M
Maiga
Ibrahim
I
Sanago
Bougouzié
B
Sangare
Drissa
D
Traoré
Hamar A
HA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000276:immunology; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D018937:Hepatitis C Antibodies / Q000032:analysis*; D006801:Humans; D008103:Liver Cirrhosis / Q000276:immunology; D008107:Liver Diseases / Q000175:diagnosis / Q000276:immunology*; D008113:Liver Neoplasms / Q000276:immunology; D008297:Male; D008302:Mali; D008875:Middle Aged; D011446:Prospective Studies
D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies