Prevalence and antimicrobial sensitivity pattern in urinary tract infection in febrile under-5s at a children's emergency unit in Nigeria.
The prevalence of urinary tract infection (UTI) in 300 consecutively admitted, febrile, preschool children with and without a focus of infection was evaluated to determine the contribution of UTI to febrile illnesses. Uncentrifuged urine was evaluated by culture and microscopy. The prevalence of UTI was 9% and was significantly higher in girls than in boys. It was also significantly higher when urine infection had been clinically suspected than in those with other diagnoses. Temperature >41 degrees C and abdominal pain were significantly associated with UTI. Other features significantly associated with UTI were fever of at least 7 days duration, a peak evaluation temperature >or=38.3 degrees C and a white blood cell count >10/mm(3). Escherichia coli, Klebsiella pneumonia and Staphylococcus aureus were the only organisms isolated and they all showed high in vitro sensitivity to clavulanic acid-potentiated amoxycillin, gentamicin and ceftriaxone but were poorly sensitive to co-trimoxazole.
Musa-Aisien
A S
AS
Department of Paediatrics, Gwagwalada Specialist Hospital, Gwagwalada, Nigeria.
Ibadin
O M
OM
Ukoh
G
G
Akpede
G O
GO
D001772:Blood Cell Count; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D004630:Emergencies; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D005334:Fever / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D008297:Male; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D012744:Sex Ratio; D013211:Staphylococcus aureus / Q000302:isolation & purification; D014552:Urinary Tract Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*