title: Effects of stress on the urinary excretory pattern of niacin catabolites, the most reliable index of niacin status, in humans.
abstract: Urinary output of water-soluble vitamins has been used as an indices for vitamin nutrition. It has been pointed out that the coefficient variance of these values is high, especially for niacin catabolites. Thus, we investigated what kinds of stress affect the catabolism using female subjects. The effects of cold exposure (as a typical physical stress), calculation exercise (a typical mental stress) and dark exposure (a typical emotional stress) on the metabolism of niacin were investigated. Of the stresses, cold exposure significantly increased urinary excretory output of the niacin metabolites. The biosynthesis of nicotinamide from Trp seemed to be increased by cold exposure.
authors.affiliation: Laboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture, Hikone, Shiga 522-8533, Japan. hokamoto@shc.usp.ac.jp
authors.forename: Hidemi
authors.initials: H
authors.lastname: Okamoto
authors.forename: Aya
authors.initials: A
authors.lastname: Ishikawa
authors.forename: Mamoru
authors.initials: M
authors.lastname: Nishimuta
authors.forename: Naoko
authors.initials: N
authors.lastname: Kodama
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yoshitake
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Fukuwatari
authors.forename: Katsumi
authors.initials: K
authors.lastname: Shibata
mesh_terms: D000328:Adult; D003080:Cold Temperature / Q000009:adverse effects; D018592:Cross-Over Studies; D003624:Darkness / Q000009:adverse effects; D005260:Female; D006801:Humans; D008606:Mental Processes / Q000502:physiology; D009525:Niacin / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism*; D013997:Time Factors
chemical_list: D009525:Niacin