title: A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH.
abstract: In this paper we report 8-quinolineboronic acid as a novel type of fluorescent probe for carbohydrates. This boronic acid responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution.
authors.affiliation: Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA.
authors.forename: Wenqian
authors.initials: W
authors.lastname: Yang
authors.forename: Jun
authors.initials: J
authors.lastname: Yan
authors.forename: Greg
authors.initials: G
authors.lastname: Springsteen
authors.forename: Susan
authors.initials: S
authors.lastname: Deeter
authors.forename: Binghe
authors.initials: B
authors.lastname: Wang
mesh_terms: D001897:Boronic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*; D012996:Solutions
chemical_list: D001897:Boronic Acids; D002241:Carbohydrates; D005456:Fluorescent Dyes; D011804:Quinolines; D012996:Solutions; C477948:8-quinolineboronic acid