Oncoproteomics: state-of-the-art.
Proteomics is a promising approach in the identification of proteins and biochemical pathways involved in carcinogenesis. Proteomic technologies are now being incorporated in oncology in the post-genomic era. Cancer involves alterations in protein expression and provides a good model not only for detection of biomarkers but also their use in drug discovery. Proteomics has an impact on diagnostics as well as drug discovery. Genomics still remains an important approach but the value of proteomics lies in the fact that most of the diagnostics and drugs target proteins. The importance of application of proteomics in oncology is recognized by the publication of this special issue of TRCT.
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D016678:Genome; D006801:Humans; D008495:Medical Oncology / Q000639:trends; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D020411:Oligonucleotide Array Sequence Analysis; D020543:Proteome; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D020543:Proteome