Autoantibody in mucous membrane pemphigoid binds to an intracellular epitope on human beta4 integrin and causes basement membrane zone separation in oral mucosa in an organ culture model.
Bhol
K C
KC
Colon
J E
JE
Ahmed
A R
AR
D000818:Animals; D001323:Autoantibodies / Q000276:immunology* / Q000378:metabolism; D001485:Basement Membrane / Q000276:immunology; D000939:Epitopes / Q000276:immunology / Q000378:metabolism; D006801:Humans; D039663:Integrin beta4 / Q000276:immunology* / Q000378:metabolism; D009061:Mouth Mucosa / Q000276:immunology; D009924:Organ Culture Techniques; D010390:Pemphigoid, Benign Mucous Membrane / Q000276:immunology*
D001323:Autoantibodies; D000939:Epitopes; D039663:Integrin beta4