title: [Studies on the marker compounds for standardization of traditional Chinese medicine "polyporus sclerotium ([symbol: see text])"].
abstract: Natural products have been used for healthcare and pharmacotherapy. Because difficulties in quality control affect their production, processing, and marketing, it is necessary to establish adequate marker compounds for their effective application. Ergosta-4,6,8(14),22-tetraen-3-one(I) was studied in the screening of the marker compounds for the standardization of Polyporus Sclerotium ([symbol: see text]), which has the advantage of easy qualitative and quantitative analysis because of its fluorescence. Its applicability in the standardization of Polyporus Sclerotium is discussed based on comparative studies of 30 crude samples of Polyporus Sclerotium and some other fungi herbs using TLC and HPLC analysis with I it as the marker compound, as well as its chemical synthesis.
authors.affiliation: Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, China, Kanebo LTD., Kampo & Healthcare Research Laboratories, 3-1 Kanebo-machi, Takaoka, Japan.
authors.forename: Dan
authors.initials: D
authors.lastname: Yuan
authors.forename: Kei-ichi
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Kaishun
authors.initials: K
authors.lastname: Bi
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kano
mesh_terms: D002783:Cholestenones / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000592:standards
chemical_list: D002783:Cholestenones; D004365:Drugs, Chinese Herbal; C015860:ergosta-4,6,8(14),22-tetraen-3-one