Human metapneumovirus in severe respiratory syncytial virus bronchiolitis.
Reverse transcription-polymerase chain reaction was used to detect segments of the M (matrix), N (nucleoprotein), and F (fusion) genes of human metapneumovirus in bronchoalveolar fluid from 30 infants with severe respiratory syncytial virus bronchiolitis. Seventy percent of them were coinfected with metapneumovirus. Such coinfection might be a factor influencing the severity of bronchiolitis.
Greensill
Julie
J
University of Liverpool, Liverpool, United Kingdom.
McNamara
Paul S
PS
Dove
Winifred
W
Flanagan
Brian
B
Smyth
Rosalind L
RL
Hart
C Anthony
CA
D001990:Bronchiolitis, Viral / Q000150:complications / Q000821:virology*; D001992:Bronchoalveolar Lavage Fluid / Q000821:virology*; D016679:Genome, Viral; D006801:Humans; D007223:Infant; D029121:Metapneumovirus / Q000235:genetics* / Q000302:isolation & purification; D018184:Paramyxoviridae Infections / Q000150:complications*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000821:virology*