title: The Y chromosome and male fertility and infertility.
abstract: Since 1995, thanks to a large number of studies, Y chromosome microdeletion screening has become part of the routine diagnostic work-up of severe male factor infertility. Many initial contradictory issues such as variability in deletion frequency, markers to be tested, presence of deletions in 'fertile' men, and genotype-phenotype correlation has been resolved. Past and present unresolved issues are discussed in this review.
authors.affiliation: Department of Clinical Physiopathology, University of Florence, Florence, Italy. c.krausz@dfc.unifi.it
authors.forename: Csilla
authors.initials: C
authors.lastname: Krausz
authors.forename: G
authors.initials: G
authors.lastname: Forti
authors.forename: Ken
authors.initials: K
authors.lastname: McElreavey
mesh_terms: D002872:Chromosome Deletion; D041322:Chromosomes, Human, Y; D005298:Fertility / Q000235:genetics*; D005817:Genetic Counseling; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male