title: Keloidal scleroderma.
abstract: A 53-year-old woman with systemic sclerosis developed numerous cutaneous nodules, resembling keloids, on her anterior chest wall. The nodules failed to respond to therapy with topical steroid, calcipotriol, or extended photochemotherapy. This is a rare, disfiguring variant of scleroderma, unresponsive to treatment, and poorly understood.
authors.affiliation: The Dermatology Centre, Hope Hospital, Manchester, UK. tcling@doctors.org.uk
authors.forename: T C
authors.initials: TC
authors.lastname: Ling
authors.forename: A L
authors.initials: AL
authors.lastname: Herrick
authors.forename: S M
authors.initials: SM
authors.lastname: Andrew
authors.forename: T
authors.initials: T
authors.lastname: Brammah
authors.forename: C E M
authors.initials: CE
authors.lastname: Griffiths
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001507:Beclomethasone / Q000627:therapeutic use; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007627:Keloid / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D011701:PUVA Therapy; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology / Q000628:therapy; D017211:Treatment Failure
chemical_list: D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids; C055085:calcipotriene; D002117:Calcitriol; D001507:Beclomethasone