title: Successful management of endodermal sinus tumor of the ovary associated with pregnancy.
abstract: BACKGROUND
  Pregnancy complicated by endodermal sinus tumor of the ovary has rarely been reported.
  
  
  METHODS
  A 32-year-old pregnant woman was found to have an ovarian tumor. At 19 weeks of gestation, tumorectomy was performed and a diagnosis of primary endodermal sinus tumor of the ovary (stage Ic) was made. Pregnancy was continued without postoperative chemotherapy. At 36 weeks of gestation, she underwent cesarean section combined with second-look laparotomy. A normal infant was delivered and there were no signs of recurrence. Subsequently, three courses of combination chemotherapy with bleomycin, etoposide, and cisplatin were administered. There was no evidence of recurrence at 27 months after initial treatment.
  
  
  CONCLUSIONS
  Successful management of endodermal sinus tumor of the ovary in a pregnant woman is reported.
authors.affiliation: Department of Obstetrics and Gynecology, Saiseikai-Utsunomiya Hospital, Utsunomiya-shi, Tochigi, Japan.
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Komiyama
authors.forename: Toru
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nakata
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Iida
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D018240:Endodermal Sinus Tumor / Q000188:drug therapy*; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*
chemical_list: D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin