Roles of galectins in vivo.
The mutational analysis of the galectin family is shedding a different light of this class of molecules. On the one hand, it appears that galectin 1 and galectin 3 are not required for the survival of mice in normal animal house conditions, while on the other hand, there seems to be several subtle, but very complex, consequences of lacking galectins during development.
Poirier
Françoise
F
Institut Jacques Monod, 2 Place Jussieu, 75251 Paris, France. poirier@ijm.jussieu.fr
D000818:Animals; D010064:Embryo Implantation / Q000502:physiology; D037161:Galectins / Q000235:genetics / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D051379:Mice; D008817:Mice, Mutant Strains; D010641:Phenotype
D037161:Galectins