MR imaging of autopsy-proved paraneoplastic limbic encephalitis in non-Hodgkin lymphoma.
We report the case of a 26-year-old man with precursor T-cell acute lymphoblastic leukemia who developed paraneoplastic limbic encephalitis that was diagnosed on the basis of MR imaging findings and was proved post mortem. In our MR imaging studies, fluid-attenuated inversion recovery images and diffusion-weighted echo-planar images clearly depicted bilateral involvement of the medial temporal lobes and multifocal involvement of the brain, whereas T2-weighted turbo spin-echo images failed to show the changes.
Thuerl
Christina
C
Department of Radiology, University of Freiburg, Freiburg, Germany.
Müller
Klaus
K
Laubenberger
Jörg
J
Volk
Benedikt
B
Langer
Mathias
M
D000328:Adult; D001344:Autopsy; D001921:Brain / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D017352:Echo-Planar Imaging; D006801:Humans; D007089:Image Enhancement; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D017254:Leukemic Infiltration; D020363:Limbic Encephalitis / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D012680:Sensitivity and Specificity; D013702:Temporal Lobe / Q000473:pathology