title: [Gastrointestinal stromal tumors: report of a clinical case and review of the literature].
abstract: In this case report, the Authors describe a case of stromal gastric tumour, in a male 65 years old, who presented gastrointestinal bleeding. Gastro-Intestinal Stromal Tumors (GISTs) are neoplasm with an incidence of 1-3 per cent of the digestive tract malignant neoplasms. The rarity of this disease, its visceral wall localization, the histopathological characteristics make the diagnosis difficult. Moreover there is no correlation between the behaviour of these neoplasms and the histologic features. Surgery represents the main treatment for GISTs based on complete resection, followed by a long-term follow-up. Chemotherapy and radiotherapy don't seem to play a crucial role in the treatment of these neoplasms. A new treatment with inhibitors of the tyrosinekinase is under discussion. Follow-up represents the only way to evaluate the effective behaviour of the disease, due to the lack of classic prognostic factors impact.
authors.affiliation: Università degli Studi di Genova, Di. S.C.A.T. Ospedale S. Martino e Cliniche Universitarie Convenzionate Sezione di Clinica Chirurgica d'Urgenza.
authors.forename: P
authors.initials: P
authors.lastname: Bronzino
authors.forename: G
authors.initials: G
authors.lastname: Cassinelli
authors.forename: E
authors.initials: E
authors.lastname: Arena
authors.forename: P C
authors.initials: PC
authors.lastname: Rassu
authors.forename: F
authors.initials: F
authors.lastname: Partipilo
authors.forename: I
authors.initials: I
authors.lastname: Rusca
authors.forename: A E
authors.initials: AE
authors.lastname: Cuneo
authors.forename: M
authors.initials: M
authors.lastname: Casaccia
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000601:surgery; D017154:Stromal Cells