Mycobacterium celatum pulmonary infection in the immunocompetent: case report and review.
Mycobacterium celatum has been shown to cause disease in immunocompromised patients. We report a case of serious pulmonary infection caused by M. celatum in an apparently immunocompetent patient and review the characteristics of two other reported cases. Clinical and radiologic symptoms and signs included cough, malaise, and weight loss associated with cavitary lesions and pulmonary infiltrates. Although M. celatum is easy to detect in clinical specimens by liquid and solid media, it may be misidentified as a member of the M. tuberculosis complex or as M. xenopi. M. celatum pulmonary infection appears to respond to antimycobacterial chemotherapy, particularly with clarithromycin.
Piersimoni
Claudio
C
Department of Clinical Microbiology, Umberto I-Torrette Hospital, Ancona, Italy. piersim@tin.it
Zitti
Pier Giorgio
PG
Nista
Domenico
D
Bornigia
Stefano
S
D005260:Female; D006801:Humans; D007121:Immunocompetence; D008171:Lung Diseases / Q000382:microbiology* / Q000503:physiopathology; D008875:Middle Aged; D009161:Mycobacterium / Q000302:isolation & purification* / Q000472:pathogenicity