title: [Progress in research on heat shock proteins in cardiovascular system].
abstract: Diverse physiological stresses (e.g., heat shock, ischemia and hemodynamics) produce multiple changes in a cell that affect metabolic processes and cellular structures. In response, stress proteins are synthesized, and are thought to mediate cytoprotection through biological function as molecular chaperones. Accumulated evidence indicates that HSP70, HSP90, HSP47, HSP32 and HSP27 play an important role during cardiac ischemia, ischemia preconditioning, cardiac hypertrophy and vascular wall injury.
authors.affiliation: Department of Physiology, Fourth Military Medical University, Xi'an 710032.
authors.forename: Jing-Jun
authors.initials: JJ
authors.lastname: Zhou
authors.forename: Yun-Long
authors.initials: YL
authors.lastname: Zhu
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Pei
authors.forename: Zhan
authors.initials: Z
authors.lastname: Gao
authors.forename: Miao-Zhang
authors.initials: MZ
authors.lastname: Zhu
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000378:metabolism* / Q000503:physiopathology; D002319:Cardiovascular System / Q000378:metabolism* / Q000503:physiopathology; D050958:HSP47 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins / Q000502:physiology; D018841:HSP90 Heat-Shock Proteins / Q000502:physiology; D006360:Heat-Shock Proteins / Q000502:physiology*; D051381:Rats; D013552:Swine
chemical_list: D050958:HSP47 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins; D018841:HSP90 Heat-Shock Proteins; D006360:Heat-Shock Proteins; C494662:Serpinh1 protein, rat