title: Synthesis, chemistry, and dynamic NMR study of new atropisomeric 4-dialkylamino-5-chloro-1,2-dithiole-3-thiones.
abstract: [reaction: see text] Reaction of N-(2-phthalimidoethyl)-N-alkylisopropylamines and S(2)Cl(2) gave atropisomeric (by dynamic NMR) 4-N-(2-phthalimidoethyl)-N-alkylamino-5-chloro-1,2-dithiole-3-thiones that quantitatively cycloadded to dimethyl or diethyl acetylenedicarboxylate to give a novel class of stable thioacid chlorides, which in turn reacted with 1 or 2 equiv of secondary amines to give thioamides.
authors.affiliation: Departamento de Química, Facultad de Ciencias, Universidad de Burgos, 09001 Burgos, Spain.
authors.forename: María
authors.initials: M
authors.lastname: García-Valverde
authors.forename: Ricardo
authors.initials: R
authors.lastname: Pascual
authors.forename: Tomás
authors.initials: T
authors.lastname: Torroba