Terpene biosynthesis in the nudibranch Doriopsilla areolata.
Biogenesis of the enantiomeric sesquiterpenes 1 and 5 of the marine nudibranch Doriopsilla areolata was investigated by feeding of [1-(13)C]glucose, [1,2-(13)C(2)]glucose, and [1,2-(13)C(2)]acetate. Evidence is presented that supports de novo origin of both compounds via mevalonic acid.
Fontana
Angelo
A
Istituto di Chimica Biomolecolare (ICB)-CNR, Via Campi Flegrei 34, 80078 Pozzuoli, Napoli, Italy. afontana@icmib.na.cnr.it
Tramice
Annabella
A
Cutignano
Adele
A
D'Ippolito
Giuliana
G
Gavagnin
Margherita
M
Cimino
Guido
G
D000085:Acetates / Q000378:metabolism*; D000818:Animals; D002247:Carbon Isotopes; D002384:Catalysis; D005947:Glucose / Q000378:metabolism*; D008798:Mevalonic Acid / Q000378:metabolism; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000378:metabolism*; D013237:Stereoisomerism; D013729:Terpenes
D000085:Acetates; D002247:Carbon Isotopes; D012717:Sesquiterpenes; D013729:Terpenes; D005947:Glucose; D008798:Mevalonic Acid