[Possible applications of Y chromosome STRs in examination of abortion tissue].
By application of Y-chromosomal STRs, DNA analysis of abortion material can be considerably facilitated since great excess of maternal DNA is tolerated without disturbing the Y-STR amplification. If paternity can't be excluded on the basis of the Y-STR haplotype, further examinations must follow, e.g. autosomal STR analysis. For this purpose, histological preparation of the abortion tissue might still be necessary. Different Y-chromosomal haplotypes of embryo and putative father usually lead to an exclusion from paternity. Based on four case examples, the feasibility of this method is discussed.
Schmidt
Ulrike
U
Institut für Rechtsmedizin, Universität Freiburg.
Meier
Nicola
N
Weisser
Hans-Joachim
HJ
Knoblich
Annette
A
Graw
Matthias
M
D000029:Abortion, Legal / Q000331:legislation & jurisprudence*; D000293:Adolescent; D000328:Adult; D002650:Child Abuse, Sexual / Q000331:legislation & jurisprudence; D002824:Chorionic Villi / Q000473:pathology; D041322:Chromosomes, Human, Y; D004247:DNA / Q000235:genetics*; D005260:Female; D006801:Humans; D007179:Incest / Q000331:legislation & jurisprudence; D008297:Male; D010334:Paternity; D011247:Pregnancy; D011902:Rape / Q000331:legislation & jurisprudence; D020080:Tandem Repeat Sequences / Q000235:genetics*
D004247:DNA