title: Total synthesis as a resource in the discovery of potentially valuable antitumor agents: cycloproparadicicol.
authors.affiliation: Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA.
authors.forename: Kana
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Robert M
authors.initials: RM
authors.lastname: Garbaccio
authors.forename: Shawn J
authors.initials: SJ
authors.lastname: Stachel
authors.forename: David B
authors.initials: DB
authors.lastname: Solit
authors.forename: Gabriela
authors.initials: G
authors.lastname: Chiosis
authors.forename: Neal
authors.initials: N
authors.lastname: Rosen
authors.forename: Samuel J
authors.initials: SJ
authors.lastname: Danishefsky
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015195:Drug Design; D018841:HSP90 Heat-Shock Proteins / Q000737:chemistry; D006801:Humans; D020128:Inhibitory Concentration 50; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018942:Macrolides; D015394:Molecular Structure; D011485:Protein Binding; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D003521:Cyclopropanes; D018841:HSP90 Heat-Shock Proteins; D007783:Lactones; D018942:Macrolides; C477936:cycloproparadicicol; C035359:monorden