title: [A case of diffuse malignant mesothelioma of the pleura with bilateral chylothorax].
abstract: We describe a case of bilateral chylothorax with malignant pleural mesothelioma. A 41-year-old woman was admitted to our hospital because of dyspnea. She had no history of exposure to asbestos. A chest radiograph and chest computed tomogram (CT) on admission revealed massive bilateral pleural effusion and a large tumor with pleural thickening in the left lateral and anterior parts of the pleura and mediastinum. Biochemical tests of pleural fluid revealed chyle. Two years before, she had been diagnosed through histological and histochemical examinations as having diffuse malignant pleural mesothelioma of the epithelial type. Chest-tube drainage was performed, and pleurodesis was induced by the intrathoracic injection of OK-432 at 10 KE per dose. The chylothorax disappeared after pleurodesis. To date, reports of malignant mesothelioma with nontraumatic chylothorax have been rare.
authors.affiliation: Fifth Department of Internal Medicine, Tokyo Medical University.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Shimizudani
authors.forename: Takahisa
authors.initials: T
authors.lastname: Morisako
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Miyao
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ito
authors.forename: Eiichi
authors.initials: E
authors.lastname: Hatao
authors.forename: Kiwamu
authors.initials: K
authors.lastname: Kiyoi
authors.forename: Akihike
authors.initials: A
authors.lastname: Sudo
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Tsuchida
authors.forename: Hideki
authors.initials: H
authors.lastname: Adachi
authors.forename: Koji
authors.initials: K
authors.lastname: Kishi
authors.forename: Hisanaga
authors.initials: H
authors.lastname: Yagyu
authors.forename: Syuji
authors.initials: S
authors.lastname: Oishi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakamura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Matsuoka
mesh_terms: D000328:Adult; D002916:Chylothorax / Q000209:etiology*; D005260:Female; D006801:Humans; D008654:Mesothelioma / Q000150:complications*; D010997:Pleural Neoplasms / Q000150:complications*