Hemostatic analysis of a patient undergoing off-pump coronary artery bypass surgery with argatroban anticoagulation.
This case describes the impact of argatroban and off-pump coronary revascularization on hemostasis as assessed by conventional hemostatic measures and Thrombelastography in a patient with heparin-induced thrombocytopenia.
Kieta
Derek R
DR
Departments of *Anesthesiology and †Surgery, The University of Alabama at Birmingham.
McCammon
Andrew T
AT
Holman
William L
WL
Nielsen
Vance G
VG
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D001120:Arginine / Q000031:analogs & derivatives; D003092:Colitis / Q000150:complications; D001026:Coronary Artery Bypass / Q000379:methods*; D017809:Fatal Outcome; D005340:Fibrinogen / Q000032:analysis; D006487:Hemostasis / Q000187:drug effects*; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D010314:Partial Thromboplastin Time; D010875:Pipecolic Acids / Q000627:therapeutic use*; D010976:Platelet Count; D011517:Prothrombin Time; D013449:Sulfonamides; D013916:Thrombelastography; D013917:Thrombin / Q000037:antagonists & inhibitors; D013921:Thrombocytopenia / Q000139:chemically induced; D014914:Whole Blood Coagulation Time
D000925:Anticoagulants; D010875:Pipecolic Acids; D013449:Sulfonamides; D005340:Fibrinogen; D006493:Heparin; D001120:Arginine; D013917:Thrombin; C031942:argatroban