Subjective memory impairment, cognitive function and depression--a community study in older Koreans.
Correlates of subjective memory impairment (SMI) were investigated using data from a community study of 1,204 individuals aged 65 or over in an urban and rural area of South Korea. SMI and depression were ascertained from the Geriatric Mental State Schedule and cognitive function from the Korean version of the Mini-Mental State Examination (MMSE-K). 686 participants had also completed the MMSE-K two years earlier. SMI was present in 22% of the sample and was associated with depression and lower MMSE-K scores. Depression and SMI were most strongly associated in the presence of cognitive impairment. SMI was weakly associated with previous cognitive decline and was not associated with APOE e4. SMI and cognitive impairment were most strongly associated in urban residents, particularly rural-to-urban migrants.
Kim
Jae-Min
JM
Department of Psychiatry, College of Medicine, Chosun University, Kwangju, Republic of Korea.
Stewart
Robert
R
Shin
Il-Seon
IS
Choi
Sung-Ku
SK
Yoon
Jin-Sang
JS
D000368:Aged; D001057:Apolipoproteins E / Q000235:genetics; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D003430:Cross-Sectional Studies; D003625:Data Collection; D003710:Demography; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D005838:Genotype; D006304:Health Status; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D011569:Psychiatric Status Rating Scales; D012423:Rural Health; D012647:Self-Assessment; D014504:Urban Health
D001057:Apolipoproteins E