The clinical use of milnacipran for depression.
We examined the relation between dosage and efficacy, and the predictors of response to milnacipran. There was no difference between 50 and 100 mg dose. However, the 100 mg dose had a faster onset of action than the 50 mg dose. An age and an episode have been predictors of milnacipran.
Morishita
Shigeru
S
Department of Psychiatry, Kawasaki Medical School, 577 Matsushima, Kurashiki-city, 701-0192 Okayama, Japan. morisita@med.kawaski-m.ac.jp
Arita
Seizaburo
S
D000328:Adult; D000367:Age Factors; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy*; D003521:Cyclopropanes / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D000078764:Milnacipran; D011569:Psychiatric Status Rating Scales; D011897:Random Allocation; D013997:Time Factors; D016896:Treatment Outcome
D000928:Antidepressive Agents; D003521:Cyclopropanes; D000078764:Milnacipran