[Roles of molecular analysis in hematopoietic stem cell transplantation].
Recent advances in molecular analysis by polymerase chain reaction(PCR) have taken a prominent position an essential part in regeneration medicine. In hematopoietic stem cell transplantation, HLA(human leukocyte antigen) typing, assessment of graft viability/rejection (chimerism analysis), and evaluation of minimal residual disease are significant for treatment strategy. Molecular analysis will play a more important role in the diversification of transplantation methods in the future of tailor-made medicines.
Hino
Masayuki
M
Department of Internal Medicine, Osaka City University Medical School.
Yamamura
Ryosuke
R
Fujino
Keizo
K
D000017:ABO Blood-Group System / Q000235:genetics; D006680:HLA Antigens; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D025202:Molecular Diagnostic Techniques; D018365:Neoplasm, Residual / Q000175:diagnosis / Q000235:genetics; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D018183:Transplantation Chimera
D000017:ABO Blood-Group System; D006680:HLA Antigens