title: Artificial cerebral aneurysm model for medical testing, training, and research.
abstract: Artificial models of cerebral aneurysms for medical training and testing of medical devices were constructed from corrosion casts of the main cerebral arteries of a human specimen. Three aneurysms with a variety of shapes were simulated at typical locations. Rigid and soft models were made of silicone using the "lost wax" technique. The transparent silicone models were anatomically accurate and reproducible copies of human vascular casts. These models could be connected in a closed circuit that used an electric pump to simulate pulsatile flow. Endovascular procedures and surgical clip application were performed under fluoroscopic or direct visual control. Surgical clipping, endoluminal coil manipulation, and consecutive hemodynamic changes were visualized by digital subtraction angiography and direct observation. The model provides trainee surgeons with an understanding of clinical conditions. New medical devices, such as platinum coils, would be experimentally implanted in the model under stable conditions. These anatomically accurate and reproducible models of cerebral vasculature and aneurysms are valuable for medical testing, training, and research.
authors.affiliation: Section of Neuroradiology, Department of Radiology, University Hospital of Geneva, Geneva, Switzerland. ksugiu@md.okayama-u.ac.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugiu
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Martin
authors.forename: Beatrix
authors.initials: B
authors.lastname: Jean
authors.forename: Philippe
authors.initials: P
authors.lastname: Gailloud
authors.forename: Shinya
authors.initials: S
authors.lastname: Mandai
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Rufenacht
mesh_terms: D016319:Corrosion Casting; D006801:Humans; D002532:Intracranial Aneurysm / Q000473:pathology*; D008422:Materials Testing / Q000295:instrumentation; D008955:Models, Cardiovascular; D017145:Models, Educational; D012106:Research / Q000295:instrumentation; D013664:Teaching Materials