[The use of gene expression differential display analysis technics in trauma research].
Gene is the regulation core of cell proliferation, differentiation and maturation. It is also the decisive factor of occurrence, progression and prognosis of many diseases. The changes in gene expression will inevitably lead to many kinds of abnormal in cells, tissue, organs even in whole biological organism. Trauma, as well as other stimulators, may bring a series complications through the abnormal expression of genes following injury. With the development of bioinformatics and molecular biology, a series of assays (so called gene expression differential display analysis technics, such as DNA microarray) have been established, which have been used to analyze differentially expressed genes effectively. These methods have been widely used in the research of tumor and other disease. This review will focus to some usage of the ways in traumatology.
Xu
Fa-Liang
FL
Institute of Military Surgery, Third Military Medical University, Chongqing 400042.
Li
Lei
L
D000818:Animals; D015870:Gene Expression; D005821:Genetic Techniques; D006801:Humans; D017403:In Situ Hybridization; D020411:Oligonucleotide Array Sequence Analysis; D016133:Polymerase Chain Reaction; D011817:Rabbits; D051381:Rats; D014947:Wounds and Injuries / Q000150:complications / Q000235:genetics* / Q000473:pathology