title: [Genetic tests in immune system-related diseases].
abstract: Recent progress in molecular medicine has revealed genes responsible for numerous instances of immunodeficiency syndrome. Such disorders have been diagnosed mainly by functional tests of both T and B lymphocytes. Genetic tests are effective in cases difficult to diagnose as well as in the detection of gene carriers. Currently, studies are underway to determine if SNP significantly impacts polygenic immunosystem-related diseases, and whether its effects influence disorders secondary to such diseases. In some diseases analysis of HLA aids in diagnosis.
authors.affiliation: Department of Clinical Pathology, Juntendo University School of Medicine.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yamada
mesh_terms: D006801:Humans; D007154:Immune System Diseases / Q000175:diagnosis* / Q000235:genetics*; D025202:Molecular Diagnostic Techniques; D020641:Polymorphism, Single Nucleotide