title: Preoperative blood pressure and catecholamines related to hypothermia during general anesthesia.
abstract: BACKGROUND
  We previously demonstrated that preoperative blood pressure values affect intraoperative hypothermia during general anesthesia. We hypothesized that increased catecholamine secretion could be responsible for the relationship between preoperative blood pressure and hypothermia.
  
  
  METHODS
  To evaluate the effect of preoperative systolic blood pressure (SBP) and plasma catecholamine levels on core temperature during general anesthesia, 40 male patients who were scheduled for open abdominal surgery were allocated to two groups: those whose preoperative SBP was 140 mmHg or greater (high SBP group, n = 20), and those whose SBP was less than 140 mmHg (normal SBP group, n = 20). Anesthesia was maintained with 0.4% isoflurane and opioids.
  
  
  RESULTS
  The average age, height, and weight of the patients in the two groups did not differ. Preoperative SBP, mean blood pressure, diastolic blood pressure and heart rate in the high SBP group were significantly higher than those in the normal SBP group. Plasma norepinephrine concentrations in the high SBP group were significantly greater than those in the normal SBP group before and 1 h after the induction of anesthesia. Tympanic membrane temperatures in the normal SBP group started to decline further just after the induction of anesthesia, more so than that in the high SBP group. The vasoconstriction threshold in the normal SBP group was significantly lower than that in the high SBP group.
  
  
  CONCLUSIONS
  These results suggest that the higher levels of preoperative catecholamine secretion contributed to the lesser degree of intraoperative hypothermia observed in the high SBP group.
authors.affiliation: Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kamigyoku, Kyoto, Japan. kasai@koto.kpu-m.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Kasai
authors.forename: M
authors.initials: M
authors.lastname: Hirose
authors.forename: T
authors.initials: T
authors.lastname: Matsukawa
authors.forename: A
authors.initials: A
authors.lastname: Takamata
authors.forename: K
authors.initials: K
authors.lastname: Yaegashi
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D000005:Abdomen / Q000601:surgery; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001794:Blood Pressure / Q000502:physiology*; D001833:Body Temperature Regulation; D002395:Catecholamines / Q000502:physiology*; D004837:Epinephrine / Q000097:blood; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D014661:Vasoconstriction / Q000502:physiology
chemical_list: D002395:Catecholamines; D009638:Norepinephrine; D004837:Epinephrine