NCI investigators find CD4 t-cell protectors.
A senior investigator with the National Cancer Institute discusses in this question-and-answer interview some recent findings that a novel human antibody is effective in preventing some strains of HIV from entering CD4 t-cells. The researchers named the newly identified antibody X5 and found that it reacts strongly against a highly conserved region of the glycoprotein gp120.
D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects*; D015658:HIV Infections / Q000276:immunology / Q000821:virology*; D006801:Humans; D008561:Membrane Fusion / Q000276:immunology*; D009316:National Institutes of Health (U.S.); D014481:United States