Pregnancy after breast cancer.
The issue of pregnancy in patients previously treated for breast cancer is controversial. This paper reviews the literature using Medline and Embase databases over the last 50 years to address the issue. Overall survival in patients treated for breast cancer who subsequently become pregnant compares favourably with controls. This paper also addresses the effects of adjuvant therapy (loco-regional and systemic) on subsequent pregnancy. Introduction of a national registry of these patients may help inform such patients in the future.
Upponi
S S
SS
Cambridge Breast Unit, Addenbrooke's Hospital, UK.
Ahmad
F
F
Whitaker
I S
IS
Purushotham
A D
AD
D000970:Antineoplastic Agents / Q000009:adverse effects; D001943:Breast Neoplasms / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000209:etiology; D011247:Pregnancy / Q000187:drug effects / Q000528:radiation effects; D011252:Pregnancy Complications, Neoplastic / Q000209:etiology*; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects; D016019:Survival Analysis; D013723:Teratogens; D013997:Time Factors
D000970:Antineoplastic Agents; D013723:Teratogens