title: Successful reimplantation of total femoral prosthesis after deep infection.
abstract: A 16-year-old boy developed a deep infection with methicillin-resistant Staphylococcus aureus 6 months after total femoral replacement including knee and hip joints. The deep infection was eradicated by the use of débridement with continuous irrigation and removal of all prosthetic components followed by insertion of an antibiotic-impregnated cement spacer. Six weeks later, the total femoral prosthesis could be successfully reimplanted with both acetabular and tibial components. Two and half years later, the patient remained free of infection. Débridement with continuous irrigation and an antibiotic-impregnated cement spacer can be a feasible technique for the treatment of deep infection after large prosthetic replacement. Furthermore, reimplantation should be performed after a short waiting period. Such treatment should be considered before deciding on amputation.
authors.affiliation: Department of Orthopedic Surgery, Hyogo College of Medicine, Hyogo, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Morimoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Futani
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ogura
authors.forename: Akira
authors.initials: A
authors.lastname: Okayama
authors.forename: Soji
authors.initials: S
authors.lastname: Maruo
mesh_terms: D000293:Adolescent; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019643:Arthroplasty, Replacement / Q000009:adverse effects* / Q000379:methods; D001843:Bone Cements / Q000627:therapeutic use*; D003646:Debridement; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects; D008297:Male; D016106:Methicillin Resistance; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D012086:Reoperation; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D013211:Staphylococcus aureus; D007507:Therapeutic Irrigation
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D001843:Bone Cements