title: Protein S deficiency in repetitive superficial thrombophlebitis.
abstract: Protein S deficiency is one of the principal congenital thrombophilias reported. The objective of this study was to assess the prevalence of protein S deficiency in patients with repetitive superficial thrombophlebitis. Thirty-six consecutive patients, 28 female and eight male, who presented with repetitive superficial thrombophlebitis (two or more cases); age range, 17 to 58 years, mean, 38.2 years; were evaluated. Coagulometry was used to determine the biologic activity of protein S. In 5.5% of the patients with repetitive superficial thrombophlebitis, protein S deficiency was detected.
authors.affiliation: Department of Cardiology and Vascular Surgery, São José do Rio Preto University School of Medicine, São Paulo, Brasil. godoyjmp@riopreto.com.br
authors.forename: José Maria Pereira
authors.initials: JM
authors.lastname: de Godoy
authors.forename: Domingos Marcolino
authors.initials: DM
authors.lastname: Braile
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain; D018455:Protein S Deficiency / Q000175:diagnosis*; D013924:Thrombophlebitis / Q000209:etiology* / Q000503:physiopathology