[Comparative study of the effect of vitamax, synergin and alpha-tocopherol on physical endurance of highly trained athletes].
The influence of vitamax, synergin, and alpha-tocopherol on the exercise performance (ultimate run on a tretbahn with increasing load) of high-rank athletes has been studied. Peculiarities of the drug action upon lipid peroxidation (LPO) in unsaturated fatty acids were studied by a chemiluminescence technique and by monitoring the malonic dialdehyde in the course of a 21-day treatment-training session and within a 5-day period after termination of the drug administration. Vitamax and synergin increase the working capacity of high-rank athletes on the 10th and 11st day of administration, respectively, while alpha-tocopherol produces such effect only on the 21st day. All the drugs studied possess antioxidant properties, which are also more pronounced for vitamax and synergin.
Rozhkova
E A
EA
Laboratory of Clinical Pharmacology and Antidoping Monitoring, Moscow Scientific-Practical Center of Sport Medicine, Zemlyanoi Val 8, Moscow, 107120 Russia.
Ordzhonikidze
Z G
ZG
Seĭfulla
R D
RD
D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology; D014142:Track and Field / Q000502:physiology*; D024502:alpha-Tocopherol / Q000494:pharmacology*
D000975:Antioxidants; D024502:alpha-Tocopherol