title: Controlled release from crosslinked degradable networks.
abstract: This article reviews controlled release from crosslinked degradable networks. Network formulations include those derived from wholly synthetic components, natural components, and combinations thereof. This includes, but is not limited to, poly(orthoesters), poly(anhydrides), poly(ethylene glycol) (PEG) derivatives, and dextran functional macromonomers. In addition, we present a discussion of the chemistry behind novel degradable networks with potential use in the controlled release realm.
authors.affiliation: Howard Hughes Medical Institute and Department of Chemical Engineering, University of Colorado-Boulder, Boulder, Colorado 80309, USA.
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Davis
authors.forename: Kristi S
authors.initials: KS
authors.lastname: Anseth
mesh_terms: D001673:Biodegradation, Environmental; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry*; D015195:Drug Design; D011108:Polymers / Q000737:chemistry*; D013678:Technology, Pharmaceutical
chemical_list: D003692:Delayed-Action Preparations; D004337:Drug Carriers; D011108:Polymers