[Role of IVIG in modern neonatology].
A newborn presents capacity to respond to specific antigens, but his immune system is still immature. Deficiency of immune function in the neonate is concerned with both innate and acquired immunity and provides to higher morbidity and mortality at this age of life. Therefore many multicentral studies on this field are performed. In the first part of the paper the authors present the development of humoral response and the role of immunoglobulins in infections of fetuses and newborns. The second part contains current views on immunoglobulin therapy in these children.
Gajewska
Elzbieta
E
Klinika Neonatologii Akademii Medycznej we Wrocławiu.
Czyzewska
Małgorzata
M
Szafrańska
Agnieszka
A
Lachowska
Monika
M
D000917:Antibody Formation / Q000276:immunology; D005315:Fetal Diseases / Q000188:drug therapy / Q000276:immunology; D005333:Fetus / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007231:Infant, Newborn / Q000276:immunology*; D007239:Infections / Q000188:drug therapy* / Q000276:immunology; D009359:Neonatology / Q000379:methods*; D011044:Poland
D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous