The synthesis and characterization of [2,3-3H] gamma-aminobutyric acid via 4-aminotetrolic acid at high specific activity.
Gamma-aminobutyric acid was labelled with tritium by the tritium gas catalytic reduction of a convenient 4-aminotetrolic acid derivative. The purified product was characterized by HPLC and tritium NMR.
Ahern
David G
DG
PerkinElmer Life Sciences Inc., 549 Albany St., Boston, MA 02118, USA.
Laseter
Anne G
AG
Filer
Crist N
CN
D000613:Aminobutyrates / Q000737:chemistry; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D007553:Isotope Labeling; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010084:Oxidation-Reduction; D014316:Tritium / Q000737:chemistry*; D005680:gamma-Aminobutyric Acid / Q000737:chemistry* / Q000378:metabolism
D000613:Aminobutyrates; D014316:Tritium; C000148:4-aminotetrolic acid; D005680:gamma-Aminobutyric Acid