title: [Influence of diet and physical activity on the course and therapy of osteoporosis].
abstract: Osteoporosis is a disease, the course of which is dependent among others on diet and physical activity. The aim of study was to find correlation between these factors and changes in bone density measured in lumbar spine. The project comprised 82 women with primary postmenopausal or senile osteoporosis treated with calcitonin, hormone replacement therapy and vitamin D. Bone density was measured by DEXA method before and after 12 month therapy. The patients were divided into four groups depending upon amount of ingested calcium and time of physical activity performed daily.
  
  
  RESULTS
  Only in the group of women (n = 32) who were physically active and presented high dietary calcium intake (over 500 mg daily) statistically significant improvement in bone density was found: T-score increased by +0.23 (p = 0.010449). No statistically significant difference of bone density in other subgroups was found.
  
  
  CONCLUSIONS
  Daily dietary calcium intake over 500 mg and physical activity performed for over 45 minutes every day provides higher bone density increase during pharmacotherapy of osteoporosis compared to pharmacotherapy alone or pharmacotherapy associated with only one of the above mentioned elements.
authors.affiliation: Katedra i Klinika Endokrynologii, Przemiany Materii i Chorób Wewnetrznych AM, Poznaniu.
authors.forename: Maciej
authors.initials: M
authors.lastname: Owecki
authors.forename: Wanda
authors.initials: W
authors.lastname: Horst-Sikorska
authors.forename: Daria
authors.initials: D
authors.lastname: Baszko-Błaszyk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Sowiński
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D015519:Bone Density / Q000187:drug effects; D002116:Calcitonin / Q000627:therapeutic use; D002136:Calcium, Dietary / Q000627:therapeutic use; D004032:Diet; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000187:drug effects; D008875:Middle Aged; D009043:Motor Activity; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy / Q000517:prevention & control; D013997:Time Factors; D014807:Vitamin D / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D002136:Calcium, Dietary; D014807:Vitamin D; D002116:Calcitonin