Antimicrobial properties of self-etching primer-bonding systems.
Self-etching primers are now considered the new generation of dentin bonding systems that modify and incorporate the bacteria-containing smear layer into their bonding mechanism. The antibacterial effects of the self-etching primers Clearfil SE Bond, Mac Bond, Imperva FL Bond, One-Up BondF and Prompt L-Pop were evaluated using the bacteria Streptococcus mutans ATCC25175, Peptostreptococcus anaerobius, Peptostreptococcus prevotii, Peptostreptococcus asaccharolyticus, Lactobacillus acidophilus, Lactobacillus catenaforme, Lactobacillus jensenii, Actinomyces odontolyticus, Porphyromonas endodontalis, Clostridium ramosum, Prevotella oris, Prevotella denticola and Fusobacterium nucleatum, with a disk diffusion method. A single-bottle total-etch dentin adhesive (Excite) was used for comparisons and chlorhexidine (0.2%) was used as the positive control. After incubation, zones of inhibited bacterial growth were observed. One-Up BondF, Prompt L-Pop and Excite showed growth inhibition for all bacterial strains. The bonding agents of Clearfil SE Bond, Mac Bond and Imperva FL Bond were unable to inhibit the growth of Lactobacillus jensenii and Actinomyces odontolyticus, while the primers of these systems produced inhibition halos to all tested microorganisms greater than that of chlorhexidine.
Cehreli
Zafer C
ZC
Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey. zaferc@hotmail.com
Stephan
Atila
A
Sener
Burcin
B
D000190:Actinomyces / Q000187:drug effects; D000473:Alkanes / Q000494:pharmacology; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002710:Chlorhexidine / Q000494:pharmacology; D003013:Clostridium / Q000187:drug effects; D017220:Dentin-Bonding Agents / Q000494:pharmacology*; D016967:Fusobacterium nucleatum / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D007778:Lactobacillus / Q000187:drug effects; D007779:Lactobacillus acidophilus / Q000187:drug effects; D008298:Maleates / Q000494:pharmacology; D008422:Materials Testing; D008689:Methacrylates / Q000494:pharmacology; D010462:Peptostreptococcus / Q000187:drug effects; D017861:Porphyromonas / Q000187:drug effects; D018720:Prevotella / Q000187:drug effects; D019279:Resin Cements / Q000494:pharmacology; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects
D000473:Alkanes; D000891:Anti-Infective Agents, Local; C438313:Clearfil SE Bond; D017220:Dentin-Bonding Agents; C420130:Excite cement; D008298:Maleates; D008689:Methacrylates; C446260:One-Up-Bond F; C408584:Prompt L-Pop; D019279:Resin Cements; C115514:Tokuso Mac Bond; C474103:imperva fluoro bond; D002710:Chlorhexidine