title: How best to ventilate? Trial design and patient safety in studies of the acute respiratory distress syndrome.
authors.forename: Robert
authors.initials: R
authors.lastname: Steinbrook
mesh_terms: D002405:Catheterization, Central Venous; D002407:Catheterization, Swan-Ganz; D002986:Clinical Trials as Topic / Q000941:ethics / Q000331:legislation & jurisprudence / Q000379:methods*; D005440:Fluid Therapy; D033161:Government Regulation; D006801:Humans; D007258:Informed Consent; D009316:National Institutes of Health (U.S.); D012107:Research Design; D012121:Respiration, Artificial / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D013990:Tidal Volume; D014481:United States; D014483:United States Dept. of Health and Human Services