Study of the addition of Grignard reagents to 2-aryl-3H-indol-3-ones.
Grignard reagents are added to the carbonyl group of 2-aryl-3H-indol-3-ones to generate 3-alkyl(or phenyl)-2-aryl-3H-indol-3-ols, which are in turn rearranged to yield 2-alkyl(or phenyl)-2-aryl-1,2-dihydro-3H-indol-3-ones.
Liu
Yahua
Y
Medicinal Chemistry Research, Pharmacia Corporation, Kalamazoo, Michigan 49001, USA.
McWhorter
William W
WW