title: Intradural, eextramedullary tuberculoma of the spinal cord as a complication of tuberculous meningitis.
abstract: An unusual case of an intradural, extramedullary spinal cord tuberculoma, as a complication of tuberculous meningitis caused by a strain susceptible to major anti-TB drugs, is described in a previously healthy, HIV-negative, 27-year-old male. The tuberculoma was detected by magnetic resonance imaging (MRI) while the patient was under conventional anti-tuberculous (anti-TB) therapy. Histopathology confirmed the diagnosis. Despite the anti-TB treatment and the surgical resection, intramedullary spreading occurred. Finally, a favorable response was achieved by prolongation of treatment accompanied by the administration of ofloxacin and cycloserine.
authors.affiliation: Dept. of Internal Medicine, Hospital of Infectious Diseases, Grigoriou Lampraki 13 str, GR-54638 Thessaloniki, Greece. skendros@med.auth.gr
authors.forename: P
authors.initials: P
authors.lastname: Skendros
authors.forename: F
authors.initials: F
authors.lastname: Kamaria
authors.forename: V
authors.initials: V
authors.lastname: Kontopoulos
authors.forename: I
authors.initials: I
authors.lastname: Tsitouridis
authors.forename: L
authors.initials: L
authors.lastname: Sidiropoulos
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004388:Dura Mater; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D014375:Tuberculoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D014390:Tuberculosis, Meningeal / Q000150:complications*; D014399:Tuberculosis, Spinal / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
chemical_list: D000995:Antitubercular Agents