title: Highly regioselective hydrogenolysis of bis(alpha-methylbenzyl)amine derivatives affected by the trifluoromethyl substituent on the aromatic ring.
abstract: [reaction: see text] The highly regioselective hydrogenolysis of bis(alpha-methylbenzyl)amine derivatives proceeded with influence not from the electronic effect but from the steric effect of the trifluoromethyl substituent on the aromatic ring to provide a practical asymmetric synthesis of trifluoromethyl-substituted alpha-phenylethylamines.
authors.affiliation: Chemical Research Center, Central Glass Co., Ltd., Kawagoe, Saitama 350-1151, Japan. mkanai@cgco.co.jp
authors.forename: Masatomi
authors.initials: M
authors.lastname: Kanai
authors.forename: Manabu
authors.initials: M
authors.lastname: Yasumoto
authors.forename: Yokusu
authors.initials: Y
authors.lastname: Kuriyama
authors.forename: Kenjin
authors.initials: K
authors.lastname: Inomiya
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Katsuhara
authors.forename: Kimio
authors.initials: K
authors.lastname: Higashiyama
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ishii