title: The tetranucleotide repeat polymorphism C2_4_4: population data and linkage disequilibria with HLA class I.
abstract: The tetranucleotide repeat locus C2_4_4 situated in the HLA class I region (6p21.3) and the HLA-ABC specificities were investigated in an Austrian population sample of 240 unrelated Caucasoid individuals. The analysis of the linkage disequilibrium between C2_4_4 and HLA class I showed several significant values, especially when factors coded for by so-called "superhaplotypes" were considered; such linkage disequilibria are of importance for the practical use of HLA coded short tandem repeats.
authors.affiliation: University of Vienna, Division of Blood Group Serology, Waehringer Guertel 18-20, A-1090 Wien, Austria.
authors.forename: Simone
authors.initials: S
authors.lastname: Stadlbacher
authors.forename: Eva-Maria
authors.initials: EM
authors.lastname: Dauber
authors.forename: Sabine
authors.initials: S
authors.lastname: Wenda
authors.forename: Barbara
authors.initials: B
authors.lastname: Glock
authors.forename: Maria
authors.initials: M
authors.lastname: Hafner
authors.forename: Günther F
authors.initials: GF
authors.lastname: Körmöczi
authors.forename: Wolfgang R
authors.initials: WR
authors.lastname: Mayr
mesh_terms: D001317:Austria; D005787:Gene Frequency; D005805:Genes, MHC Class I; D006801:Humans; D015810:Linkage Disequilibrium; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic