The photobleaching of disulfonated aluminium phthalocyanine in microbial systems.
Front-face illumination spectroscopic techniques were used to study photobleaching of disulfonated aluminium phthalocyanine (AlPcS2) in the bacteria and yeast cells Escherichia coil, Porphyromonas gingivalis (Gram-negative bacteria), Streptococcus mutans (a Gram-positive bacterium), and the yeast Candida albicans. The photobleaching of AlPcS2 with the microbes studied is complex, involving reactive species generated by type I and type II processes with the rate dependent on the relative contributions of the different photobleaching mechanisms. The average rate of photobleaching of the AlPcS2 monomer in the presence of both E. coli and C. albicans increases as the fluence of the illumination source decreases. The effects of oxygen and sensitiser concentration on the rate of AlPcS2 photobleaching in these systems are also investigated.
Lacey
Jackie A
JA
Department of Chemistry, Imperial College of Science, Technology and Medicine, London, UK.
Phillips
David
D
D002176:Candida albicans / Q000378:metabolism / Q000528:radiation effects; D004926:Escherichia coli / Q000378:metabolism / Q000528:radiation effects; D007211:Indoles / Q000378:metabolism / Q000528:radiation effects*; D009942:Organometallic Compounds / Q000378:metabolism / Q000528:radiation effects*; D038761:Photobleaching; D017319:Photosensitizing Agents / Q000378:metabolism / Q000528:radiation effects; D016966:Porphyromonas gingivalis / Q000378:metabolism / Q000528:radiation effects; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry; D013295:Streptococcus mutans / Q000378:metabolism / Q000528:radiation effects
D007211:Indoles; D009942:Organometallic Compounds; D017319:Photosensitizing Agents; C064331:aluminum phthalocyanine disulfonate