title: [Risk of sensitization to Anisakis simplex among the members of the families of patients with anisakiasis].
abstract: OBJECTIVE
  Infection by anisakid nematodes is associated with consumption of raw fish. The aim of this paper was to determine the prevalence of sensitization among members of families of patients with anisakiasis.
  
  
  METHODS
  Eleven asymptomatic members of families of patients diagnosed with anisakiasis were studied by means of IgE-immunoblotting. The frequency of sensitization was compared with the prevalence in a normal population from the same geographic area.
  
  
  RESULTS
  A very high frequency of sensitization was observed among patients' family members (73%) as compared with the prevalence in normal population (12%) (p < 0.001).
  
  
  CONCLUSIONS
  All members of the family of a patient diagnosed with anisakiasis should be studied to determine whether they are sensitized.
authors.affiliation: Centro de Investigación Clínica y Medicina Preventiva. Instituto de Salud Carlos III. Madrid. España. mlcsoto@hotmail.com
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Caballero
authors.forename: Ignacio
authors.initials: I
authors.lastname: Moneo
mesh_terms: D000818:Animals; D017129:Anisakiasis / Q000453:epidemiology / Q000276:immunology*; D017163:Anisakis / Q000276:immunology / Q000302:isolation & purification; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D007114:Immunization; D015151:Immunoblotting / Q000379:methods; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male; D009679:Nuclear Family; D010375:Pedigree; D012306:Risk
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D007073:Immunoglobulin E