title: Thinning of the anterior capsule associated with congenital aniridia.
abstract: OBJECTIVE
  To report the unusual finding of intraoperative fragility of the anterior capsule in some patients with congenital aniridia and determine the histopathologic etiology of this finding.
  
  
  METHODS
  Cincinnati Eye Institute, Cincinnati, Ohio, USA.
  
  
  METHODS
  Anterior lens capsule specimens were obtained from aniridic and nonaniridic patients during cataract surgery. The intraoperative behavior of each capsule was noted, after which the specimens were submitted for histopathologic evaluation.
  
  
  RESULTS
  All anterior capsule specimens from the nonaniridic patients were of normal thickness. Some, but not all, anterior capsule specimens from the aniridic patients were remarkably thin. Thin capsules were associated with extreme intraoperative fragility.
  
  
  CONCLUSIONS
  Greater awareness of anterior capsule fragility in some aniridic patients may reduce the risk of capsule complications and lead to safer surgical outcomes.
authors.affiliation: Department of Ophthalmology University of Cincinnati College of Medicine, Cincinnati, Ohio 45219, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Schneider
authors.forename: Robert H
authors.initials: RH
authors.lastname: Osher
authors.forename: Scott E
authors.initials: SE
authors.lastname: Burk
authors.forename: Travis B
authors.initials: TB
authors.lastname: Lutz
authors.forename: Richard
authors.initials: R
authors.lastname: Montione
mesh_terms: D000328:Adult; D000368:Aged; D015783:Aniridia / Q000150:complications*; D000869:Anterior Eye Segment; D002387:Cataract Extraction; D005260:Female; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D007905:Lens Diseases / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged