One-pot synthesis of polyfunctionalized cyclic urea derivatives.
[reaction: see text] Unexpectedly, imidazolidin-2-ones are easily obtained from beta-keto esters upon treatment with tert-butyl nosyloxycarbamate and calcium oxide under mild conditions. The structure of the product was established by X-ray crystallography.
Fioravanti
Stefania
S
Dipartimento di Chimica dell'Università degli Studi di Roma La Sapienza, P.le Aldo Moro 2, I-00185 Roma, Italy.
Marchetti
Fabio
F
Morreale
Alberto
A
Pellacani
Lucio
L
Tardella
Paolo A
PA
D017610:Calcium Compounds / Q000737:chemistry; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
D017610:Calcium Compounds; D010087:Oxides; D014508:Urea; C016538:lime