title: Principal component analysis as a method to facilitate fast detection of transient-evoked otoacoustic emissions.
abstract: Transient-evoked otoacoustic emissions (TEOAE) are acoustic signals coming from the inner ear (outer hair cells of the cochlea) after acoustic stimulation by clicks. They can be used to investigate the status of the peripheral hearing system. Some of their potential applications (e.g., their use as a tool in newborn hearing screening programs) are deeply related to the duration of each recording session. This duration can be strongly reduced by applying a principal component analysis approach to a set of TEOAE recorded from the same ear at different stimulus levels averaging only a few sweeps (a maximum of 100 versus the classical 260). The PCA approach is shown to be able to enhance the signal-to-noise ratio and, in turn, to allow a correct detection of the responses. Results of the application of this approach in comparison with responses recorded from the same subjects with the classical technique will be shown.
authors.affiliation: Istituto di Ingegneria Biomedica CNR, Piazza Leonardo da Vinca 32, 20133 Milan, Italy. paolo.ravazzani@polimi.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Ravazzani
authors.forename: Gabriella
authors.initials: G
authors.lastname: Tognola
authors.forename: Marta
authors.initials: M
authors.lastname: Parazzini
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Grandori
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D000465:Algorithms; D001300:Audiometry, Evoked Response / Q000379:methods; D001309:Auditory Threshold / Q000502:physiology; D006320:Hearing Tests / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D025341:Principal Component Analysis / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity