Treatment of Candida albicans endocarditis: case report and a review.
Candida albicans endocarditis occurs mostly in patients with congenital heart disease; open heart surgery is the greatest predisposing factor. We report on a child with truncus arteriosus communis and a large Candida vegetation within the prosthetic pulmonary valve, causing severe right ventricular outflow tract obstruction. Treatment was performed successfully by surgery and administration of liposomal amphotericin B (AmBisome) and 5-flucytosine.
Hauser
M
M
Dept. of Pediatric Cardiology, German Heart Center, Lazarettstrasse 36, D-80636 Munich, Germany. hauser@dhm.mhn.de
Hess
J
J
Belohradsky
B H
BH
D000666:Amphotericin B / Q000627:therapeutic use; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D002177:Candidiasis / Q000453:epidemiology / Q000628:therapy*; D002648:Child; D004696:Endocarditis / Q000150:complications / Q000382:microbiology* / Q000628:therapy*; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008297:Male
C068538:liposomal amphotericin B; D000666:Amphotericin B