title: Novel consecutive beta- and gamma-turn mimetics composed of alpha-aminooxy tripeptides.
abstract: [structure: see text] To develop novel consecutive beta- and gamma-turn mimetics, we designed and characterized alpha-aminooxy tripeptides (trimers) consisting of oxanipecotic acid dimer and alpha-aminooxy acid. According to FT-IR and NMR data, as well as ab initio quantum calculations, the trimers adopted unusual folded structures with consecutive beta- and gamma-turnlike conformations.
authors.affiliation: Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Bong-Hyeon
authors.initials: BH
authors.lastname: Baek
authors.forename: Myung-Ryul
authors.initials: MR
authors.lastname: Lee
authors.forename: Kwang-Yon
authors.initials: KY
authors.lastname: Kim
authors.forename: Ung-In
authors.initials: UI
authors.lastname: Cho
authors.forename: Doo Wan
authors.initials: DW
authors.lastname: Boo
authors.forename: Injae
authors.initials: I
authors.lastname: Shin
mesh_terms: D019281:Dimerization; D009682:Magnetic Resonance Spectroscopy; D018716:Molecular Mimicry; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D017433:Protein Structure, Secondary; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D010455:Peptides