title: Incidental control of rosacea by somatostatin.
abstract: BACKGROUND
  The precise pathomechanism of rosacea remains elusive. The disease commonly requires long-term treatments using topical or oral therapies.
  
  
  OBJECTIVE
  This report presents incidental findings about the possible modulatory role of somatostatin in the outcome of rosacea.
  
  
  METHODS
  Four patients presenting long-standing recalcitrant facial rosacea were treated with octreotide for diabetic retinopathy.
  
  
  RESULTS
  Rosacea improved rapidly and even cleared without any recurrence in 3 of the patients.
  
  
  CONCLUSIONS
  The beneficial effect might be attributed to inhibitory actions on the sebaceous gland, the neovascularization and/or on the inflammatory process.
authors.affiliation: Department of Dermatopathology, University Medical Center of Liège, Belgium.
authors.forename: Claudine
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: Pascale
authors.initials: P
authors.lastname: Quatresooz
authors.forename: Gérald E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003930:Diabetic Retinopathy / Q000150:complications / Q000188:drug therapy*; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D012393:Rosacea / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D006728:Hormones; D015282:Octreotide