title: [Comparative study of the effect of vitamax, synergin and alpha-tocopherol on physical endurance of highly trained athletes].
abstract: The influence of vitamax, synergin, and alpha-tocopherol on the exercise performance (ultimate run on a tretbahn with increasing load) of high-rank athletes has been studied. Peculiarities of the drug action upon lipid peroxidation (LPO) in unsaturated fatty acids were studied by a chemiluminescence technique and by monitoring the malonic dialdehyde in the course of a 21-day treatment-training session and within a 5-day period after termination of the drug administration. Vitamax and synergin increase the working capacity of high-rank athletes on the 10th and 11st day of administration, respectively, while alpha-tocopherol produces such effect only on the 21st day. All the drugs studied possess antioxidant properties, which are also more pronounced for vitamax and synergin.
authors.affiliation: Laboratory of Clinical Pharmacology and Antidoping Monitoring, Moscow Scientific-Practical Center of Sport Medicine, Zemlyanoi Val 8, Moscow, 107120 Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Rozhkova
authors.forename: Z G
authors.initials: ZG
authors.lastname: Ordzhonikidze
authors.forename: R D
authors.initials: RD
authors.lastname: Seĭfulla
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology; D014142:Track and Field / Q000502:physiology*; D024502:alpha-Tocopherol / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D024502:alpha-Tocopherol