Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient.
Levofloxacin is a fluoroquinolone antibiotic commonly used to treat respiratory, urinary tract, skin and soft-tissue infections. Levofloxacin is generally well tolerated and has fewer reported side effects than other fluoroquinolones. We present a case of levofloxacin-associated severe hepatocellular injury. The hepatitis resolved soon after discontinuation of levofloxacin.
Schwalm
Jon-David
JD
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON.
Lee
Christine H
CH
D000208:Acute Disease; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002481:Cellulitis / Q000150:complications / Q000188:drug therapy*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D064704:Levofloxacin; D008297:Male; D015242:Ofloxacin / Q000009:adverse effects*; D006435:Renal Dialysis
D000890:Anti-Infective Agents; D064704:Levofloxacin; D015242:Ofloxacin