Hemihypertrophy and the Chiari I malformation.
We report two children with hemihypertrophy and Chiari I malformation (CIM) and review the extant medical literature regarding CIM and overgrowth disorders. We propose that these two entities do not represent a spurious association but rather share a common dysembryology of mesoderm.
Tubbs
R Shane
RS
Department of Cell Biology, University of Alabama at Birmingham, Alabama 35233, USA. richard.tubbs@ccc.uab.edu
Smyth
Matthew D
MD
Wellons
John C
JC
Oakes
W Jerry
WJ
D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D002648:Child; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male