Inhibition of dipeptidylpeptidase IV (DPP IV, CD26) activity modulates surface expression of CTLA-4 in stress-induced abortions.
Rüter
Jens
J
Department of Internal Medicine/Psychosomatics, Charité Campus Mitte, Luisenstr. 13A, Berlin, Germany.
Demuth
Hans-Ulrich
HU
Arck
Petra C
PC
Hoffmann
Torsten
T
Klapp
Burghard F
BF
Hildebrandt
Martin
M
D000069594:Abatacept; D000022:Abortion, Spontaneous / Q000517:prevention & control*; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics; D060908:CTLA-4 Antigen; D018819:Dipeptidyl Peptidase 4 / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005434:Flow Cytometry; D018796:Immunoconjugates; D007166:Immunosuppressive Agents / Q000037:antagonists & inhibitors; D007371:Interferon-gamma / Q000097:blood; D007532:Isoleucine / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D016131:Lymphocyte Subsets / Q000276:immunology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA; D011247:Pregnancy; D011480:Protease Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use*; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D013601:T-Lymphocytes / Q000276:immunology*
C475121:2-cyano-1-isoleucylpyrrolidine; D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007166:Immunosuppressive Agents; D011480:Protease Inhibitors; D011759:Pyrrolidines; D007532:Isoleucine; D000069594:Abatacept; D007371:Interferon-gamma; D018819:Dipeptidyl Peptidase 4