Down-regulation of 5-lipoxygenase activity and leukotriene production by prolonged exposure to lipopolysaccharide.
Brock
Thomas G
TG
Division of Pulmonary and Critical, Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109-0642, USA.
D000818:Animals; D001094:Arachidonate 5-Lipoxygenase / Q000187:drug effects / Q000235:genetics*; D015777:Eicosanoids / Q000378:metabolism; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects / Q000502:physiology*; D015289:Leukotrienes / Q000378:metabolism; D008070:Lipopolysaccharides / Q000494:pharmacology*; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000201:enzymology*; D051381:Rats
D015777:Eicosanoids; D015289:Leukotrienes; D008070:Lipopolysaccharides; D001094:Arachidonate 5-Lipoxygenase