title: Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry.
abstract: ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.
authors.affiliation: Department of Chemistry, University of Wollongong, Northfields Avenue, Wollongong 2522, Australia.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Beck
authors.forename: Rajesh
authors.initials: R
authors.lastname: Gupta
authors.forename: Thitima
authors.initials: T
authors.lastname: Urathamakul
authors.forename: Nyree L
authors.initials: NL
authors.lastname: Williamson
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Sheil
authors.forename: Janice R
authors.initials: JR
authors.lastname: Aldrich-Wright
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Ralph
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D007364:Intercalating Agents / Q000737:chemistry / Q000378:metabolism*; D009841:Oligonucleotides / Q000737:chemistry / Q000378:metabolism; D009942:Organometallic Compounds / Q000737:chemistry / Q000378:metabolism*; D012428:Ruthenium / Q000737:chemistry* / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization; D013379:Substrate Specificity
chemical_list: D007364:Intercalating Agents; D009841:Oligonucleotides; D009942:Organometallic Compounds; D012428:Ruthenium; D004247:DNA