Non-invasive assessment of coronary flow velocity reserve: a new method using transthoracic Doppler echocardiography.
Transthoracic Doppler echocardiography (TTDE) allows noninvasive flow measurement in the distal left anterior descending artery (LAD). The feasibility of detecting coronary flow by contrast-enhanced TTDE with second harmonic technique was assessed, the coronary flow velocity reserve (CFVR) was evaluated in comparison to intracoronary Doppler flow (ICD) analysis and the CFVR after PTCA in LAD was investigated. In 77 (96%) of 80 patients, CFVR was successfully determined with intravenous adenosine infusion. Doppler signal quality was evaluated in the first 46 patients by use of intravenous Levovist infusion and second harmonic technique. The Doppler flow was not visible in 1. patient only. CFVR determined from TTDE (2.77 +/- 0.65) was correlated closely with those from ICD (2.88 +/- 0.78) measurements (y = 0.73x + 0.67, r = 0.87, P < 0.001). In conclusion, TTDE is a feasible method and provides reliable data on CFVR which can be used for follow-up after PTCA.
Yang
Ya
Y
Institute of Cardiovascular Disease, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Bartel
Thomas
T
Eggebrecht
Holger
H
Latina
Loredana
L
von Birgelen
Clemems
C
Caspari
Guido
G
Wang
Xinfang
X
Erbel
Raimund
R
D000241:Adenosine / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D003287:Contrast Media; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003326:Coronary Circulation / Q000502:physiology*; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000187:drug effects / Q000503:physiopathology; D015150:Echocardiography, Doppler / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides; D011237:Predictive Value of Tests; D014665:Vasodilator Agents / Q000008:administration & dosage
D003287:Contrast Media; D011134:Polysaccharides; D014665:Vasodilator Agents; C059891:SHU 508; D000241:Adenosine