title: Salivary characteristics of diabetic children.
abstract: Salivary components may suffer variations that can be detected by chemical determinations. The aim of this work was to determine physical and biochemical characteristics of the saliva of a group of diabetic children compared to those of a control group. Relation to oral health indices was also determined. Twenty diabetic children (3-15-years-old) and 21 control children (5-12-years-old) were included in this study. Total proteins, sugars and calcium were determined by colorimetric methods, and glucose, urea, alpha-amylase and acid phosphatase by enzymatic methods. Our results demonstrated that acidic pH, diminished salivary flow rate and excess foam are usually present in saliva of diabetic children. Total sugars, glucose, urea and total proteins were greater in diabetic patients than controls, while calcium values were decreased. These differences were confirmed by the discrimination test. Diabetic children have higher DMFT-dmft-deft and DMFS-dmfs-defs values compared to those of the control children despite their lower sugar intake. Some salivary components in addition to the diminished flow rate could be involved in the characterization of the oral health state of diabetic children.
authors.affiliation: Biologic Chemistry, Faculty of Dentistry, National University of Tucumán, San Miguel de Tucumán, Argentina. melopez@fo.unt.edu.ar
authors.forename: María Elena
authors.initials: ME
authors.lastname: López
authors.forename: María Eugenia
authors.initials: ME
authors.lastname: Colloca
authors.forename: Rafael Gustavo
authors.initials: RG
authors.lastname: Páez
authors.forename: Judit Nora
authors.initials: JN
authors.lastname: Schallmach
authors.forename: Myriam Adriana
authors.initials: MA
authors.lastname: Koss
authors.forename: Amalia
authors.initials: A
authors.lastname: Chervonagura
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis; D000293:Adolescent; D000704:Analysis of Variance; D002118:Calcium / Q000032:analysis; D002241:Carbohydrates / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003124:Colorimetry; D004245:DMF Index; D003774:Dental Plaque Index; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000503:physiopathology; D005260:Female; D005947:Glucose / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D016014:Linear Models; D008297:Male; D010512:Periodontal Index; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000032:analysis; D012636:Secretory Rate / Q000502:physiology; D014508:Urea / Q000032:analysis; D000516:alpha-Amylases / Q000032:analysis
chemical_list: D002241:Carbohydrates; D012471:Salivary Proteins and Peptides; D014508:Urea; D000135:Acid Phosphatase; D000516:alpha-Amylases; D005947:Glucose; D002118:Calcium