title: Painful soft-tissue reaction to injectable Norian SRS calcium phosphate cement after curettage of enchondromas.
abstract: A prospective single-cohort study was designed to include 20 patients with enchondromas but was stopped because of poor early results. Four patients with an enchondroma, three in the proximal humerus and one in the distal femur, were treated by curettage and filling of the defect with Norian SRS cement. Clinical and radiological follow-up including CT and MRI was carried out for 18 months. All three patients with lesions in the proximal humerus had severe pain and limited movement of the shoulder. The radiological and CT appearances of the cement were unchanged at follow-up. There were characteristic appearances of synovitis and periosteitis on MRI in two patients. Since the cement induces a soft-tissue reaction the bony cavity should be sealed with the curetted and burred bone after curettage and introduction of Norian cement, especially in sites where a tourniquet cannot be applied.
authors.affiliation: Department of Orthopaedic Surgery, University of Graz, Austria.
authors.forename: Heike
authors.initials: H
authors.lastname: Welkerling
authors.forename: Johann
authors.initials: J
authors.lastname: Raith
authors.forename: Norbert
authors.initials: N
authors.lastname: Kastner
authors.forename: Claus
authors.initials: C
authors.lastname: Marschall
authors.forename: Reinhard
authors.initials: R
authors.lastname: Windhager
mesh_terms: D001843:Bone Cements / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000601:surgery*; D002130:Calcium Phosphates / Q000009:adverse effects*; D002812:Chondroma / Q000601:surgery*; D003475:Curettage; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus / Q000601:surgery; D010149:Postoperative Pain / Q000139:chemically induced*; D010522:Periostitis / Q000139:chemically induced; D011446:Prospective Studies; D013585:Synovitis / Q000139:chemically induced
chemical_list: D001843:Bone Cements; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous