title: [Systematic review of randomised controlled trial of iodised salt for preventing iodine deficiency disorders].
abstract: OBJECTIVE
  To assess the effect of iodised salt for preventing iodine deficiency disorders.
  
  
  METHODS
  Cochrane systematic review.
  
  
  RESULTS
  Four randomised controlled trials were included. Subgroup analysis performed lay on different ages, interventions and controls. Prevalence of goitre was reduced close to 5% when using distributed iodised salt and market iodised salt plus iodine oil capsule which showed more effective than using market iodised salt alone (OR = 0.10, 95% CI: 0.02 - 0.17). The latter's prevalence of goitre was 14.7%. When using market iodised salt, the iodine urea excretion level showed different results in children group in different countries. Basically, the market iodised salt for preventing iodine deficiency of pregnancy women were effective, but a part of them did not achieve to the ideal status of iodine nutrition.
  
  
  CONCLUSIONS
  The needs to be strictly controlled quality of iodised salt and market iodised salt plus iodised oil capsule thus can effectively reduce the prevalence of iodine deficiency disorders. However there was not enough evidence to support that market iodised salt can effectively eliminate these disorders, particularly in children. More eligibility trials are needed for providing more evidences.
authors.affiliation: Department of Clinical Epidemiology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Taixiang
authors.initials: T
authors.lastname: Wu
authors.forename: Guanjian
authors.initials: G
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Li
mesh_terms: D000328:Adult; D002648:Child; D002681:China / Q000453:epidemiology; D006042:Goiter / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D007455:Iodine / Q000008:administration & dosage* / Q000172:deficiency*; D016032:Randomized Controlled Trials as Topic; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*
chemical_list: D017673:Sodium Chloride, Dietary; C034024:iodized salt; D007455:Iodine