title: Management of non-neoplastic ovarian cysts with sclerotherapy.
abstract: OBJECTIVE
  To evaluate sclerotherapy with alcohol and erythromycin in the management of simple ovarian cysts.
  
  
  METHODS
  Twenty-four simple ovarian cysts were subjected to sclerotherapy with alcohol and erythromycin. All procedures were performed under local anesthesia and in an outpatient setting. Cytological examination was carried out in all cases and two patients were excluded from the study because of suspicious cytological results. The patients were followed up monthly with color Doppler sonography for more than 12 months.
  
  
  RESULTS
  Cyst fluid was serous in 17 cases and dark-chocolate colored in seven cases. The volume of aspirated fluid ranged from 100 to 220 ml. The size of ovarian masses and cyst-wall thickness ranged from 5.5 to 8.5 cm and 1.5 to 5 mm, respectively. Cytological analysis of 15 cysts revealed acellular sediment, seven cysts were compatible with endometrioma, and two were reported as suspicious. During the 12-month follow-up, seven cyst recurrences were detected.
  
  
  CONCLUSIONS
  Aspiration and sclerotherapy with alcohol and erythromycin are followed by a relatively high recurrence rate when the aspirate is bloody. However, patients with a simple cyst that is painful or liable to torsion could benefit from sclerotherapy. Such patients, who are at low risk for malignancy, are relieved with sclerotherapy while avoiding surgery.
authors.affiliation: Department of Obstetrics and Gynecology, Medical School, Harran University, Sanliurfa, Turkey. hasankafali@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Kafali
authors.forename: S
authors.initials: S
authors.lastname: Yurtseven
authors.forename: F
authors.initials: F
authors.lastname: Atmaca
authors.forename: I
authors.initials: I
authors.lastname: Ozardali
mesh_terms: D000293:Adolescent; D000328:Adult; D001585:Benzoyl Peroxide / Q000627:therapeutic use*; D004338:Drug Combinations; D004917:Erythromycin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010048:Ovarian Cysts / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D012008:Recurrence; D012597:Sclerosing Solutions / Q000627:therapeutic use; D015911:Sclerotherapy; D018615:Ultrasonography, Doppler, Color
chemical_list: D004338:Drug Combinations; D012597:Sclerosing Solutions; C097386:benzoyl peroxide, erythromycin drug combination; D004917:Erythromycin; D001585:Benzoyl Peroxide