[Hepatosplenic localization of cat scratch disease in immunocompetent adults. Two cases].
The infective agent responsible for cat scratch disease, Bartonella henselae, is a rare cause of hepatic granulomatosis in immunocompetent adults. Clinical features include a prolonged fever or more typical symptoms such as lymphadenopathy associated with painful hepatomegaly and a fever following a cat scratch or bite. Images of micronodular hepatosplenic lesions on abdominal ultrasonography or computed tomography scan along with epithelioid granulomas in a liver biopsy can suggest this diagnosis. It is established with a serology by indirect immunofluorescence or by ELISA and/or the presence of Bartonella henselae DNA evidenced by PCR in the liver biopsy. We report two cases of hepatosplenic localizations of cat scratch disease in a 41-year-old woman and a 44-year-old man presenting asthenia and fever associated with a biological inflammatory syndrome and elevated liver enzymes.
Le Tallec
Véronique
V
Service d'Hépato-Gastroentérologie, Centre Hospitalier Universitaire, 4, rue Larrey, 49033 Angers cedex 01.
Abgueguen
Pierre
P
Pichard
Eric
E
Chennebault
Jean-Marie
JM
Bellec
Véronique
V
Delbos
Valérie
V
Rousselet
Marie-Christine
MC
Dib
Nina
N
Boyer
Jean
J
D000328:Adult; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008107:Liver Diseases / Q000175:diagnosis*; D008297:Male; D013158:Splenic Diseases / Q000175:diagnosis*