[Early glottic carcinoma: a clinico-pathological study].
The aim of the present study is to evaluate histopathological features of malignization of laryngeal dysplasia and recurrence of early glottic carcinoma.


METHODS
A prospective study was perform in a cohort of 134 patients who underwent surgery between 1992/99 at the ENT department of the Complutense University of Madrid. Tumor localization, malignization rate and recurrence rate were studied in 68 cases of laryngeal dysplasia, 11 of in situ-carcinoma and 55 of microinvasive carcinoma.


RESULTS
Nine laryngeal dysplasias experienced invasive carcinoma (13%) and six patients with invasive glottic carcinoma had laryngeal recurrence (11%), all of them with anterior commisure involvement. Eight patients underwent total laryngectomy for recurrence (6%) and three patients died of laryngeal cancer.


CONCLUSIONS
Anterior commisure involvement was the most important risk factor in early glottic carcinoma.
Martín Villares
C
C
Departamento Cirugía II-ORL, Hospital Clínico San Carlos Universidad Complutense de Madrid (UCM).
Poch Broto
J
J
Ortega Medina
L
L
González Gimeno
M J
MJ
Iglesias Moreno
M C
MC
Santos Corchero
J M
JM
D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D015331:Cohort Studies; D005931:Glottis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D008866:Microsurgery / Q000379:methods; D009367:Neoplasm Staging; D011446:Prospective Studies