Molecular Mechanisms Leading to the Development of Diabetes.
Current therapy for type 2 diabetes relies mainly on several approaches intended to reduce hyperglycemia. Several major studies have shown that the appropriate long-term management of glycemia is critical to reduce the risk of vascular complications. Thus, the goal of future treatments of the disease will be to intervene when early clinical signs, such as impaired glucose tolerance, first manifest and to exploit the knowledge of the molecular mechanisms of insulin secretion by the beta-cells as well as insulin action in its target tissues to develop new drugs to accomplish a tight glycemic control. (c) 2002 Prous Science. All rights reserved.
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