title: [Multi-variate regression analysis of clinicopathological characteristics and prognosis of colorectal cancer].
abstract: OBJECTIVE
  To evaluate the relationship between clinicopathologic features and prognosis of colorectal cancer after surgical treatment.
  
  
  METHODS
  The clinical characteristics, pathologic features and survival rate of 761 patients with colorectal cancer after surgical treatment were univariately and multivariately analyzed.
  
  
  RESULTS
  The overall 3- and 5-year survival rates of patients with colorectal cancer after surgical treatment were 62.9% and 60.7% with a median survival of 1,825 days. The factors of gross findings, degree of differentiation, infiltration, nodal and distant metastasis and neoplastic intestinal obstruction influenced the survival rate by univariate analysis. The factors of Dukes stage, gross tumor configuration, intramural spread and differentiation degree were available independent prognostic factors through multivariate analysis.
  
  
  CONCLUSIONS
  Dukes stage, as the most important available independent prognostic factor (P < 0.0005), is able to assess the postoperative survival.
authors.affiliation: Department of Gastrointestinopancreatic Surgery, First Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China.
authors.forename: Jian-ping
authors.initials: JP
authors.lastname: Wang
authors.forename: Zu-li
authors.initials: ZL
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Wen-guang
authors.initials: WG
authors.lastname: Dong
authors.forename: Yi-hua
authors.initials: YH
authors.lastname: Huang
authors.forename: Jian-zhang
authors.initials: JZ
authors.lastname: Qin
authors.forename: Wen-hua
authors.initials: WH
authors.lastname: Zhan
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D012044:Regression Analysis; D015996:Survival Rate