title: Breast masses: removal of all US evidence during biopsy by using a handheld vacuum-assisted device--initial experience.
abstract: OBJECTIVE
  To assess the effects of removal of all ultrasonographic (US) evidence of breast lesions by using a vacuum-assisted biopsy (VAB) device.
  
  
  METHODS
  Thirty-four women with breast masses underwent US-guided biopsy with an 11-gauge VAB device, with which removal of all evidence of the lesion was attempted. Histologic findings were compared with results of surgery and follow-up imaging. Patient tolerance and perceptions of the procedure and the ability of the procedure to eliminate a palpable finding were evaluated with questionnaires and findings at follow-up physical examination.
  
  
  RESULTS
  The biopsy protocol was completed in all cases. Twenty-six benign lesions (76%) and eight malignancies (24%) were diagnosed. After VAB, 10 patients (29%) underwent surgery on the basis of histologic findings of invasive carcinoma (n = 7), ductal carcinoma in situ (n = 1), lobular neoplasia (n = 1), or atypical ductal hyperplasia (n = 1). VAB resulted in complete excision of four of 10 lesions: two of eight malignancies and two of two benign lesions. Among 21 patients with benign lesions who underwent 6-month follow-up imaging, eight (38%) had a definite residual mass. At 6-month follow-up examination, VAB was seen to have eliminated the palpable abnormality in seven (88%) of eight patients with initially palpable benign masses. Thirty-two patients (94%) described no or mild pain during biopsy, and 33 patients (97%) rated care as excellent.
  
  
  CONCLUSIONS
  After removal of all US evidence of breast masses with a VAB device, there was a substantial probability that residual lesion that was not visualized during the procedure would later be found at surgery or follow-up imaging. A palpable mass (< or =1.2 cm in mean diameter) was eliminated in 88% of cases, and patient tolerance and perceptions of the procedure were favorable.
authors.affiliation: Department of Radiology, Baystate Medical Center, 759 Chestnut St, Springfield, MA 01199, USA.
authors.forename: David E
authors.initials: DE
authors.lastname: March
authors.forename: Bret F
authors.initials: BF
authors.lastname: Coughlin
authors.forename: Ruth B
authors.initials: RB
authors.lastname: Barham
authors.forename: Robert A
authors.initials: RA
authors.lastname: Goulart
authors.forename: Stephen V
authors.initials: SV
authors.lastname: Klein
authors.forename: Martin E
authors.initials: ME
authors.lastname: Bur
authors.forename: James L
authors.initials: JL
authors.lastname: Frank
authors.forename: Grace
authors.initials: G
authors.lastname: Makari-Judson
mesh_terms: D001706:Biopsy / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D004867:Equipment Design; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D017060:Patient Satisfaction; D011446:Prospective Studies; D015203:Reproducibility of Results; D014463:Ultrasonography