Synthesis of (1R,2R,7R,7aS)-1-hydroxymethyl-2,3,5,6,7,7a-hexahydropyrrolizidine-1,2,7-triol from rosmarinine degradation.
A novel tetrahydroxypyrrolizidine alkaloid (6) was obtained from rosmarinine degradation in 23% yield (isolated from Senecio callosas).
Nieto-Alvarez
David Aaron
DA
Departamento de Química, Centro de Investigación y de Estudios Avanzados del I.P.N. Mexico D.F., A.P. 14-740. C.P. 07000, Mexico.
Calderón
José S
JS
Mancilla
Teresa
T
D019906:Nuclear Magnetic Resonance, Biomolecular; D011763:Pyrrolizidine Alkaloids / Q000138:chemical synthesis / Q000737:chemistry*; D012674:Senecio / Q000737:chemistry*
D011763:Pyrrolizidine Alkaloids