Cadaveric renal transplantation from a non-heart-beating pediatric donor into adult recipients.
BACKGROUND
The use of cadaveric pediatric kidneys has been suggested as a means to overcome organ shortage, but is debated because of technical complications and an increased incidence of functional allograft impairment.


METHODS
We experienced 2 cases of cadaveric renal transplantation from a non-heart-beating pediatric donor.


RESULTS
In our cases, transplanted kidneys achieved good graft function and proteinuria due to glomerulosclerosis was not recognized.


CONCLUSIONS
Previous reports indicate that in transplantation from pediatric donors into adults recipients, glomerular sclerosis occurs as the reason for impairment of grafts. Further, cadaveric renal transplantation from a non-heart-beating donor has a warm ischemia time and an increased risk of hyperfiltrated injury and graft failure. If transplantation of pediatric kidneys into adults from a non-heart-beating donor is performed, BMI and BSA must be carefully considered in the selection of recipients in order to avoid imbalance between nephron supply and metabolic demands and to insure successful, healthy grafts.
Nakatani
Tatsuya
T
Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585 Japan.
Uchida
Junji
J
Yamazaki
Takeshi
T
Iwai
Tomoaki
T
Naganuma
Toshihide
T
Kim
Taku
T
Sugimura
Kazunobu
K
D015992:Body Mass Index; D001830:Body Surface Area; D002102:Cadaver; D002648:Child; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology; D008297:Male; D008875:Middle Aged