title: Update on pediatric acute respiratory distress syndrome.
abstract: Pediatric acute respiratory distress syndrome (ARDS) remains an important challenge for the intensive care clinician. ARDS, which can result from either direct lung injury or from a "downstream" inflammatory process, is manifested by profound hypoxemia and respiratory failure. The care of pediatric ARDS is based on a meticulous, multidisciplinary, intensive care team approach. This review discusses the changing definition of ARDS and available intensive care treatment modalities, including newer lung-protective mechanical ventilation strategies and adjunct therapies. The prognosis of children suffering pediatric ARDS is examined with a look toward areas of potential future intervention in this often deadly disease.
authors.affiliation: Division of Pediatric Pharmacology and Critical Care, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. mxa35@po.cwru.edu.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Anderson
mesh_terms: D000208:Acute Disease; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal / Q000379:methods / Q000639:trends*; D011379:Prognosis; D012121:Respiration, Artificial / Q000379:methods / Q000639:trends; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy / Q000628:therapy*; D012138:Respiratory Therapy / Q000379:methods / Q000639:trends*; D016896:Treatment Outcome; D014481:United States