Treatment of Old World cutaneous leishmaniasis with intralesionally injected meglumine antimoniate using a Dermojet device.
Pentavalent antimonial compounds, the mainstay in the treatment of the various forms of leishmaniasis, have considerable toxicity, are difficult to administer and expensive. We describe a safe and efficient therapeutic modality using a spring-loaded and air-powered device for the intralesional injection of a high-velocity meglumine antimoniate microspray in a patient with cutaneous leishmaniasis.
Bogenrieder
Thomas
T
Department of Dermatology, University of Regensburg, Germany. bogenrieder@wistar.upenn.edu
Lehn
Norbert
N
Landthaler
Michael
M
Stolz
Wilhelm
W
D000293:Adolescent; D000965:Antimony / Q000008:administration & dosage* / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D004867:Equipment Design; D006801:Humans; D015552:Injections, Intralesional / Q000295:instrumentation* / Q000379:methods; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy*; D008297:Male; D008536:Meglumine / Q000008:administration & dosage* / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000008:administration & dosage* / Q000627:therapeutic use
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony