title: [A case of astrocytoma with extracranial extension after malignant transformation].
abstract: A case of astrocytoma with extracranial extension after malignant transformation is presented. The patient was a 58-year-old female who suffered from headache. The initial magnetic resonance imaging (MRI) demonstrated a slightly hyperintense tumor on T 2-weighted images in the tip of the left temporal lobe, and no contrast enhancement on gadolinium-enhanced T 1-weighted images(Gd-T 1 WI). On digital subtraction angiography, there was no tumor staining. The initial diagnosis was made as low-grade astrocytoma. However two months later, her symptoms aggravated suddenly. MRI revealed a remarkably growing tumor with ring-like enhancement on Gd-T 1 WI. She underwent a temporal lobectomy, which pathologically demonstrated a glioblastoma. After surgery, chemotherapy and radiotherapy were performed. The tumor invades the skull base and extended into the infratemporal fossa 25 months after surgery.
authors.affiliation: Department of Radiology, Akita University School of Medicine, 1-1-1 Hondo, Akita City, Akita 010-8543, Japan.
authors.forename: Ikuo
authors.initials: I
authors.lastname: Sakuma
authors.forename: Noriaki
authors.initials: N
authors.lastname: Tomura
authors.forename: Koichi
authors.initials: K
authors.lastname: Omachi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Jiro
authors.initials: J
authors.lastname: Watarai
authors.forename: Toshio
authors.initials: T
authors.lastname: Sasajima
authors.forename: Kazuo
authors.initials: K
authors.lastname: Mizoi
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009367:Neoplasm Staging; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000473:pathology*