title: Job characteristics and serum lipid profile in Japanese rural workers: the Jichi Medical School Cohort Study.
abstract: To observe the association between adverse psychosocial job characteristics, measured by the Karasek job demand-control questionnaire, and a lipid profile, cross-sectional analyses were performed for a Japanese rural working population. The study population comprised 3,333 male and 3,596 female actively employed workers, aged 65 years and under. Among men, higher psychological demands were associated with high total cholesterol levels, with an adjusted difference from the top to bottom tertiles of 3.3 mg/dl (F = 3.03; p = 0.048). High demands were also positively associated with the total/HDL cholesterol ratio (F = 3.94; p = 0.020). Neither job control nor job strain (the ratio of demands to control) was associated with any of the lipid levels in either gender. A psychologically demanding job may be associated with an unfavorable lipid profile, but the impact of job strain on atherogenic lipids is negligible.
authors.affiliation: Okayama University School of Medicine and Dentistry, Social and Environmental Life Sciences, Social Medicine and Longevity Sciences, Hygiene and Preventive Medicine, Okayama, Japan.
authors.forename: Akizumi
authors.initials: A
authors.lastname: Tsutsumi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Kayaba
authors.forename: Shizukiyo
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Tadao
authors.initials: T
authors.lastname: Gotoh
authors.forename: Naoki
authors.initials: N
authors.lastname: Nago
authors.forename: Seishi
authors.initials: S
authors.lastname: Yamada
authors.forename: Masafumi
authors.initials: M
authors.lastname: Mizooka
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Sakai
authors.forename: Shinya
authors.initials: S
authors.lastname: Hayasaka
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood* / Q000453:epidemiology*; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D015331:Cohort Studies; D015897:Comorbidity; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D004784:Environmental Monitoring / Q000379:methods / Q000706:statistics & numerical data*; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D007587:Job Description; D008019:Life Style; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology; D009790:Occupations / Q000706:statistics & numerical data*; D011336:Probability; D011584:Psychology; D012307:Risk Factors; D012424:Rural Population; D012577:Schools, Medical; D017678:Sex Distribution; D013315:Stress, Psychological / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL