[Study on the incidence and risk factors for in-hospital stroke in patients with acute myocardial infarction].
OBJECTIVE
To determine the incidence and risk factors for in-hospital stroke in patients with acute myocardial infarction (AMI).


METHODS
Two thousand one hundred and thirty-three patients with acute myocardial infarction were studied retrospectively. History, demographic, clinical, thrombolytic and anticoagulant data of AMI were obtained through review of the medical record. The relative risk of in-hospital stroke in patients with AMI was estimated using multiple nonconditional logistic regression to adjust for potential confounding factors.


RESULTS
Among 2,133 consecutive patients admitted with acute myocardial infarction to hospitals in Shandong and Hubei provinces, 98 (4.59%) experienced strokes during hospitalization. In our analysis, anterior infarction was the most important risk factor for in-hospital stroke (ischemic and hemorrhagic) in patients with AMI (RR = 7.04), followed by history of hypertension (RR = 3.41), previous stroke (RR = 1.69), atrial fibrillation (RR = 2.22), advanced age (RR = 1.04), and higher heart rate at enrollment (RR = 1.03).


CONCLUSIONS
The incidence of in-hospital stroke in patients with AMI increased with lower rate of using thrombolytic agents. Thrombolytic therapy was noticed as a protective factor for stroke after AMI. The risk factors for in-hospital stroke with AMI were history of hypertension, previous stroke, atrial fibrillation, advanced age, anterior infarction, and higher heart rate at enrollment.
Pi
Yansheng
Y
Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Zhang
Wei
W
Shi
Luyuan
L
Wang
Ruifang
R
Xia
Zhihong
Z
Li
Li
L
Zhang
Yun
Y
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications*; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology