title: A network of rice genes associated with stress response and seed development.
abstract: We used a systematic approach to build a network of genes associated with developmental and stress responses in rice by identifying interaction domains for 200 proteins from stressed and developing tissues, by measuring the associated gene expression changes in different tissues exposed to a variety of environmental, biological, and chemical stress treatments, and by localizing the cognate genes to regions of stress-tolerance trait genetic loci. The integrated data set suggests that similar genes respond to environmental cues and stresses, and some may also regulate development. We demonstrate that the data can be used to correctly predict gene function in monocots and dicots. As a result, we have identified five genes that contribute to disease resistance in Arabidopsis.
authors.affiliation: Torrey Mesa Research Institute, 3115 Merryfield Row, San Diego, CA 92121, USA. bcooper912@worldnet.att.net
authors.forename: Bret
authors.initials: B
authors.lastname: Cooper
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Clarke
authors.forename: Paul
authors.initials: P
authors.lastname: Budworth
authors.forename: Joel
authors.initials: J
authors.lastname: Kreps
authors.forename: Don
authors.initials: D
authors.lastname: Hutchison
authors.forename: Sylvia
authors.initials: S
authors.lastname: Park
authors.forename: Sonia
authors.initials: S
authors.lastname: Guimil
authors.forename: Molly
authors.initials: M
authors.lastname: Dunn
authors.forename: Peter
authors.initials: P
authors.lastname: Luginbühl
authors.forename: Cinzia
authors.initials: C
authors.lastname: Ellero
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Goff
authors.forename: Jane
authors.initials: J
authors.lastname: Glazebrook
mesh_terms: D048948:14-3-3 Proteins; D017360:Arabidopsis / Q000235:genetics; D018744:DNA, Plant / Q000235:genetics; D015870:Gene Expression; D017343:Genes, Plant; D008969:Molecular Sequence Data; D012275:Oryza / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D010641:Phenotype; D010749:Phosphoprotein Phosphatases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D010935:Plant Diseases / Q000235:genetics; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D030821:Plants, Genetically Modified; D021122:Protein Subunits; D040641:Quantitative Trait Loci; D012639:Seeds / Q000254:growth & development; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D020798:Two-Hybrid System Techniques; D014446:Tyrosine 3-Monooxygenase / Q000235:genetics / Q000378:metabolism
chemical_list: D048948:14-3-3 Proteins; D018744:DNA, Plant; D010940:Plant Proteins; D021122:Protein Subunits; D014157:Transcription Factors; D014446:Tyrosine 3-Monooxygenase; D010749:Phosphoprotein Phosphatases