title: Occurrence of false positives during testing for antibodies to hepatitis C virus among volunteer blood donors in India.
abstract: The hepatitis C virus antibody statuses of only 11 (21.5%) of 51 initially reactive samples from volunteer blood donors could be confirmed by using additional screening and confirmatory assays; 23 (45%) were negative by all subsequent assays. Seventeen samples (33.3%) gave variable results in the different assays. The core and NS5 antigens were most immunogenic. An algorithm for serological screening of volunteer blood donors in blood banks of developing countries is suggested.
authors.affiliation: Department of Clinical Virology, Christian Medical College, Vellore 632 004, Tamil Nadu, India.
authors.forename: Sukanya
authors.initials: S
authors.lastname: Raghuraman
authors.forename: Thenmozhi
authors.initials: T
authors.lastname: Subramaniam
authors.forename: Dolly
authors.initials: D
authors.lastname: Daniel
authors.forename: Gopalan
authors.initials: G
authors.lastname: Sridharan
authors.forename: Priya
authors.initials: P
authors.lastname: Abraham
mesh_terms: D001782:Blood Donors; D005189:False Positive Reactions; D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000175:diagnosis*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D015151:Immunoblotting; D007124:Immunoenzyme Techniques / Q000379:methods
chemical_list: D018937:Hepatitis C Antibodies