[Antiphospholipid antibodies in HELLP syndrome: clinical and biological study in 68 women].
OBJECTIVE
Pregnancy complicated by the HELLP syndrome and antiphospholipid syndrome have rarely been reported. We report a study on anticardiolipin antibodies in HELLP syndrome.


METHODS
Between March 1996 and September 1999, anticardiolipin antibodies were checked in all women with HELLP syndrome hospitalised in a maternity of the North of France. The women with positive anticardiolipin antibodies were seen month later in a internal medicine department.


RESULTS
In the period 68 women with HELLP syndrome were checked for anticardiolipin antibodies. Apl were present in 9 patients (Incidence 42.8/1000 HELLP Year). They persisted after the accident only in 3 patients. Antiphospholipid syndrome was diagnosed in 2 patients, prevalence between the HELLP syndrome for the 42 month period was 0.03.


CONCLUSIONS
HELLP syndrome may be a manifestation linked to the antiphospholipid syndrome and may revealed it.
Queyrel
V
V
Service de médecine interne, hôpital Claude-Huriez, CHRU de Lille, rue Polonovski, 59037 cedex, Lille, France. v-queyrel@chru-lille.fr <v-queyrel@chru-lille.fr>
Ducloy-Bouthors
A-S
AS
Michon-Pasturel
U
U
Hachulla
E
E
Dubucquoi
S
S
Caron
C
C
Vallat
A-S
AS
Subtil
D
D
Dufour
P
P
Lambert
M
M
Hatron
P-Y
PY
Devulder
B
B
Puech
F
F
D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis* / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000276:immunology* / Q000473:pathology; D005260:Female; D017359:HELLP Syndrome / Q000276:immunology* / Q000473:pathology; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies
D017152:Antibodies, Antiphospholipid