title: Effects of intermittent cycle exercise on intramyocellular lipid use and recovery.
abstract: The purpose of this investigation was to compare intramyocellular lipid (IMCL) changes in skeletal muscle in nine moderately trained subjects after 45 min of interval cycling and through 1 h of recovery. The exercise session was continuous with alternating cycling intensity achieving 50 (3 min) and 110% (2 min) of ventilatory threshold. Spectra from the vastus lateralis were acquired before, immediately after, and 60 min following exercise using a 1.5 T Signa whole-body magnet (point-resolved spectroscopy sequence, echo time 60 ms, transverse relaxation time 2000 ms, 128 acquisitions, and 20 mm3 voxel). Immediately following exercise, IMCL concentration decreased 38% compared to pre-exercise levels (P < 0.05). Fitness level and baseline IMCL were not correlated with changes in IMCL following exercise (P > 0.05). In the 60-min recovery, IMCL was reduced 30% compared to baseline (P < 0.05) and did not recover. In contrast, a nonexercising control group showed no change in IMCL. Our results suggest that IMCL decreased significantly following 45 min of interval cycling, with little recovery in the hour following.
authors.affiliation: Human Performance Laboratory, University of New Mexico, Albuquerque, New Mexico 87106, USA. lwhite@hhp.ufl.edu
authors.forename: Lesley J
authors.initials: LJ
authors.lastname: White
authors.forename: Robert A
authors.initials: RA
authors.lastname: Robergs
authors.forename: Wilmer L
authors.initials: WL
authors.lastname: Sibbitt
authors.forename: Michael A
authors.initials: MA
authors.lastname: Ferguson
authors.forename: Sean
authors.initials: S
authors.lastname: McCoy
authors.forename: William M
authors.initials: WM
authors.lastname: Brooks
mesh_terms: D000328:Adult; D015308:Anaerobic Threshold; D015444:Exercise; D005080:Exercise Test; D006801:Humans; D050356:Lipid Metabolism; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000378:metabolism*; D009142:Musculoskeletal Physiological Phenomena; D012123:Pulmonary Ventilation