title: Parathyroid hormone-related protein in pancreatic exocrine cancer associated with hypercalcaemia.
abstract: Hypercalcaemia is a common complication of malignancy seen in about 10% of cases of advanced cancer. Although hypercalcaemia is not uncommon with endocrine tumour of the pancreas, hypercalcaemia with cancer of the exocrine pancreas unrelated to bone metastasis has been rarely reported. We report a case of undifferentiated pancreatic cancer with severe hypercalcaemia due to parathyroid hormone-related protein produced by the tumour cells that did not respond to medical management.
authors.affiliation: Department of Medicine and Surgery, St Mary's Hospital, Newport, Isle of Wight.
authors.forename: P
authors.initials: P
authors.lastname: Bandyopadhyay
authors.forename: S
authors.initials: S
authors.lastname: Baksi
authors.forename: D
authors.initials: D
authors.lastname: Bandyopadhyay
authors.forename: C U
authors.initials: CU
authors.lastname: Patel
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood*; D010190:Pancreatic Neoplasms / Q000097:blood / Q000150:complications*; D044162:Parathyroid Hormone-Related Protein; D010446:Peptide Fragments / Q000097:blood*; D011506:Proteins
chemical_list: D009363:Neoplasm Proteins; D044162:Parathyroid Hormone-Related Protein; D010446:Peptide Fragments; D011506:Proteins; C066077:parathyroid hormone-related protein (1-84)