[Influence of dithranol therapy on clinical status and serum calcitonin concentrations in patients with common psoriasis].
The aim of this work was to study the effects of external dithranol therapy of psoriatic patients on the clinical status and serum calcitonin concentrations. This was done on 19 patients with common psoriasis using Cignoderm in the short contact therapy. Calcitonin concentration in serum samples was determined before and after a 14-day therapy. Results obtained before were compared with concentrations after dithranol treatment and with results in control group. Serum TSH was also measured in serum samples from both groups at the very beginning time. The determinations showed statistically significant lower serum TSH level in psoriatic patients before therapy vs. control and significant, negative correlation with calcitonin concentration in those patients. After a 14-day dithranol therapy a significant calcitonin concentration decrease as well as clinical effects were observed in the investigated group.
Bendkowski
Witold
W
Kliniczny Oddział Dermatologii Szpitala Specjalistycznego, Zabrzu.
Hadas
Ewa
E
Swietochowska
Elzbieta
E
Wielkoszyński
Tomasz
T
Ostrowska
Zofia
Z
Szapska
Bozena
B
D000287:Administration, Topical; D000328:Adult; D000875:Anthralin / Q000494:pharmacology / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002116:Calcitonin / Q000097:blood* / Q000187:drug effects*; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D002116:Calcitonin; D000875:Anthralin