title: Biological inorganic chemistry at the beginning of the 21st century.
abstract: Advances in bioinorganic chemistry since the 1970s have been driven by three factors: rapid determination of high-resolution structures of proteins and other biomolecules, utilization of powerful spectroscopic tools for studies of both structures and dynamics, and the widespread use of macromolecular engineering to create new biologically relevant structures. Today, very large molecules can be manipulated at will, with the result that certain proteins and nucleic acids themselves have become versatile model systems for elucidating biological function.
authors.affiliation: Beckman Institute, California Institute of Technology, Pasadena, CA 91125, USA. hbgray@caltech.edu
authors.forename: Harry B
authors.initials: HB
authors.lastname: Gray
mesh_terms: D015393:Chemistry, Bioinorganic / Q000639:trends*; D003576:Electron Transport Complex IV / Q000737:chemistry; D004777:Environment; D006418:Heme; D008670:Metals; D017433:Protein Structure, Secondary
chemical_list: D008670:Metals; D006418:Heme; D003576:Electron Transport Complex IV