title: Osteomyelitis of the pelvis caused by Rhodococcus equi in a two-year-old horse.
abstract: A 2-year-old female Quarter Horse was evaluated for hind limb lameness, fever (40 degrees C [104 degrees F]), and lethargy of 2 weeks' duration. Hypoproteinemia characterized by hypoalbuminemia and hyperfibrinogenemia was detected. Abdominal ultrasonography revealed thickening of the right dorsal colon wall. Treatment was instituted for putative right dorsal coliis. Lameness evaluation localized signs of pain to the lumbar vertebrae or pelvis. Radiography performed with the horse standing and nuclear scintigraphy revealed no abnormalities. Ventrodorsal pelvic radiography revealed a focal area of bony lysis and proliferation involving the cranial portion of the pubic symphysis. Aspiration yielded purulent exudate containing Rhodococcus equi, which was susceptible to erythromycin. Treatment included surgical debridement of the abscess and oral administration of erythromycin and rifampin. The horse's hind limb lameness completely resolved within 20 days. Infections of the pubic symphysis should be considered when lameness localized to the pelvis is associated with fever and an inflammatory leukogram.
authors.affiliation: Department of Clinical Science, College of Veterinary Medicine, Kansas State University, Manhattan 66506-5606, USA.
authors.forename: Stuart C
authors.initials: SC
authors.lastname: Clark-Price
authors.forename: Bonnie R
authors.initials: BR
authors.lastname: Rush
authors.forename: Earl M
authors.initials: EM
authors.lastname: Gaughan
authors.forename: Judy H
authors.initials: JH
authors.lastname: Cox
mesh_terms: D000193:Actinomycetales Infections / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement / Q000662:veterinary; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D006736:Horses; D007794:Lameness, Animal / Q000209:etiology; D010019:Osteomyelitis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D011631:Pubic Symphysis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D011859:Radiography; D016929:Rhodococcus equi / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin