Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma. A case report.
BACKGROUND
Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC.


METHODS
We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor.


CONCLUSIONS
This case documents the role of FNA cytology in confirming HPC.
Ghaffar
Hasan
H
Department of Pathology, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, Maryland 21287, USA.
Parwani
Anil
A
Rosenthal
Dorothy L
DL
D000328:Adult; D018952:Antigens, CD34 / Q000378:metabolism; D014408:Biomarkers, Tumor; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000556:secondary*
D018952:Antigens, CD34; D014408:Biomarkers, Tumor