[Status of intragastric acidity in diabetes mellitus patients with chronic gastroduodenal ulcers].
1. The daily gastric pH monitoring in patients with diabetes of the first type failed to reveal any differences in the state of intragastric acidity, as compared with the control group of healthy people. A tendency towards increased stomach acidity is observed only during the first five years of type I diabetes, and it is normalized later on. 2. 68% patients with type II diabetes had normal gastric acidity, and only 23% had hypoacidity. A tendency towards moderate hypoacidity in the stomach body was observed on average when the disease lasted for more than 5 years. 3. In case of type I diabetes in combination with chronic gastroduodenal ulcers at the acute stage, the intragastric pH in the whole group was reduced to the degree of pronounced hyperacidity with the decompensation of alkalization in the antral portion of the stomach. 4. In case of type II diabetes in combination with chronic gastroduodenal ulcers at the acute stage, there also was a tendency towards hyperacidity in the stomach for the whole group. Moderate intragastric hyperacidity was recorded in case of stomach ulcers, and pronounced intragastric hyperacidity was recorded in case of duodenal ulcers.
Fedorchenko
Iu L
IuL
State Medical University of the Far East, Khabarovsk.
D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology*; D005744:Gastric Acid; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D010437:Peptic Ulcer / Q000150:complications / Q000503:physiopathology*