MK 886 functions as a radiomimetic agent: genomic responses related to oxidative stress, the cell cycle, proliferation and programmed cell death in Panc-1 cells.
Anderson
Ken M
KM
Departments of Medicine and of Biochemistry, Rush Medical College, Chicago, Il. 60612, USA.
Alrefai
Waddah
W
Anderson
Colin
C
Bonomi
Philip
P
Harris
Jules
J
D017209:Apoptosis / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology*; D020411:Oligonucleotide Array Sequence Analysis; D018384:Oxidative Stress / Q000187:drug effects / Q000502:physiology*; D010190:Pancreatic Neoplasms / Q000235:genetics; D014407:Tumor Cells, Cultured; D002722:Chlorobenzenes
D007211:Indoles; D016859:Lipoxygenase Inhibitors; C060893:MK-886; D002722:Chlorobenzenes