title: Transnasal repair of unilateral choanal atresia.
abstract: OBJECTIVE
  To evaluate the outcomes of the surgical correction of unilateral choanal atresia using a transnasal approach.
  
  
  METHODS
  Over a 36-months period (from 1999 to 2001), seven children underwent endoscopic endonasal repair of an unilateral choanal atresia using the microdebrider (powered instrumentation). At the end of the procedure, topical application of Mitomycin-C was performed. No postoperative nasal stenting was inserted. Clinical characteristics of these patients, CT scan examination, complications of the procedure and outcomes were analysed and compared to historical cases treated in the same institution from 1990 to 1998.
  
  
  RESULTS
  Seven patients (2 M/5F) (age 6 to 46 months) presented with primary unilateral choanal atresia and were operated during the period from 1999 to 2001. All the patients were symptomatic before surgical correction. No patients showed other facial anomaly. Of the 7 patients procedures, 6 (85.7%) remained patent (follow-up range 12 to 36 months). Mean surgical repair per patient before obtaining patent choana was 1.14. One patient required surgical transnasal revision nine months after the initial procedure with a patent choanal after this second procedure (follow-up 9 months). Minor turbinoseptal synechiae diagnosed 6 months after the surgical correction occurred in one patient and was the only postoperative complication. When compared to historical cases of unilateral choanal atresia (19 patients from 1990 to 1998) repaired without endoscopic control and without Mitomycin-C, it was shown that this current method provided better results; mean surgical repair per patient; 1.14 vs 1.89 and 85.7% of patent choanae at twelve months vs 47.3%.
  
  
  CONCLUSIONS
  An endoscopic endonasal approach without postoperative stenting, using the microdebrider seems to us the treatment of choice for unilateral choanal atresia. The exact role of the topical application of Mitomycin-C needs to be further investigated.
authors.affiliation: Cliniques Universitaires Saint-Luc, ENT Department, Avenue Hippocrate 10, Brussels, Belgium. philippe.rombaux@orlo.ucl.ac.be
authors.forename: Ph
authors.initials: P
authors.lastname: Rombaux
authors.forename: C
authors.initials: C
authors.lastname: de Toeuf
authors.forename: M
authors.initials: M
authors.lastname: Hamoir
authors.forename: P
authors.initials: P
authors.lastname: Eloy
authors.forename: B
authors.initials: B
authors.lastname: Bertrand
authors.forename: F
authors.initials: F
authors.lastname: Veykemans
mesh_terms: D002675:Child, Preschool; D002754:Choanal Atresia / Q000601:surgery*; D003646:Debridement; D004724:Endoscopy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use; D013517:Otorhinolaryngologic Surgical Procedures; D012189:Retrospective Studies
chemical_list: D016685:Mitomycin