title: [Early glottic carcinoma: a clinico-pathological study].
abstract: The aim of the present study is to evaluate histopathological features of malignization of laryngeal dysplasia and recurrence of early glottic carcinoma.
  
  
  METHODS
  A prospective study was perform in a cohort of 134 patients who underwent surgery between 1992/99 at the ENT department of the Complutense University of Madrid. Tumor localization, malignization rate and recurrence rate were studied in 68 cases of laryngeal dysplasia, 11 of in situ-carcinoma and 55 of microinvasive carcinoma.
  
  
  RESULTS
  Nine laryngeal dysplasias experienced invasive carcinoma (13%) and six patients with invasive glottic carcinoma had laryngeal recurrence (11%), all of them with anterior commisure involvement. Eight patients underwent total laryngectomy for recurrence (6%) and three patients died of laryngeal cancer.
  
  
  CONCLUSIONS
  Anterior commisure involvement was the most important risk factor in early glottic carcinoma.
authors.affiliation: Departamento Cirugía II-ORL, Hospital Clínico San Carlos Universidad Complutense de Madrid (UCM).
authors.forename: C
authors.initials: C
authors.lastname: Martín Villares
authors.forename: J
authors.initials: J
authors.lastname: Poch Broto
authors.forename: L
authors.initials: L
authors.lastname: Ortega Medina
authors.forename: M J
authors.initials: MJ
authors.lastname: González Gimeno
authors.forename: M C
authors.initials: MC
authors.lastname: Iglesias Moreno
authors.forename: J M
authors.initials: JM
authors.lastname: Santos Corchero
mesh_terms: D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D015331:Cohort Studies; D005931:Glottis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D008866:Microsurgery / Q000379:methods; D009367:Neoplasm Staging; D011446:Prospective Studies