[Experimental study of vasoligation in the treatment and prevention of benign prostatic hyperplasia].
OBJECTIVE
To investigate the possibility and efficacy of vasoligation and deferent vein ligation in treating and preventing benign prostatic hyperplasia(BPH).


METHODS
40 male pooches were divided into A, B, C and D groups randomly. Each group has 10 pooches group A and B were made into the model of BPH. Two years later, the pooches in group A and C accepted the operation of vasoligation and deferent vein ligation on both sides. Group B and D only accepted the operation of dissection and relieving its deferent duct. Then continuing to feed the 40 pooches after the operation, they were killed another two years later. After taking out their prostates and calculating their volume and weight, the sections of the prostates were checked by microscope to observe their histology and pathology changes.


RESULTS
There were significant differences of weight and volume as well as the changes of histology and pathology between group A and group C (P < 0.01). It was the same with group B and D (hyperplasia changes).


CONCLUSIONS
Vasoligation and deferent vein ligation before benign prostatic hyperplasia at pooches grow-up stage can reduce the extent of BPH at old age, and treatment after benign prostatic hyperplasia can make prostatic tissue appear different degrees of atrophy.
Guo
Xian-Kun
XK
Institute of Andrology, Medical College, Three Gorges University, Yichang, Hubei 443003, China.
Bian
Jiang
J
Nie
Yong
Y
Zhang
Zhao-Xiang
ZX
Li
Wen-Li
WL
Zhang
Yan
Y
Gao
Wu-Yang
WY
Feng
Yong-Ju
YJ
Cheng
Shi-Ping
SP
Xiang
Yan-Jiu
YJ
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D008026:Ligation; D008297:Male; D011470:Prostatic Hyperplasia / Q000517:prevention & control / Q000628:therapy*; D014659:Vasectomy