title: [Mathematical modeling -- an objective assessment of new medicines and treatment technologies].
abstract: An objective method of studying effectiveness of new medicines and methods of treatment is mathematical modeling. On the basis of mathematical processing of the pooled data obtained in the control group of patients an individual prognostic formula can be made which predicts the only outcome for each patient. When studying a new medicine or method of treatment in each patient under test his prognostic outcome is compared to the real one. An improvement of the real outcome as compared to the prognostic one points to the effectiveness of the new medicine used. An objective and individual approach to the assessment of the result after the end of each case of treatment allows the further perspectiveness of the work done and the number of necessary tests to be efficiently estimated.
authors.forename: M I
authors.initials: MI
authors.lastname: Gromov
authors.forename: D M
authors.initials: DM
authors.lastname: Shirokov
mesh_terms: D004358:Drug Therapy / Q000592:standards*; D006801:Humans; D008954:Models, Biological; D010956:Plasmapheresis / Q000379:methods; D011379:Prognosis; D012774:Shock, Traumatic / Q000628:therapy; D013530:Surgical Wound Infection / Q000628:therapy