Enantioresolution and absolute configurations of chiral meta-substituted diphenylmethanols as determined by X-ray crystallographic and 1H NMR anisotropy methods.
meta-Substituted diphenylmethanols were enantioresolved by the method of chiral phthalic acid yielding enantiopure alcohols. Their absolute configurations were unambiguously determined by X-ray crystallography of chiral phthalate esters and/or by the (1)H NMR anisotropy method using 2-methoxy-2-(1-naphthyl)propionic acid.
Kosaka
Masashi
M
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan.
Sugito
Takeo
T
Kasai
Yusuke
Y
Kuwahara
Shunsuke
S
Watanabe
Masataka
M
Harada
Nobuyuki
N
Job
Gabriel E
GE
Shvet
Alex
A
Pirkle
William H
WH