New transcutaneous jaundice device with two optical paths.
OBJECTIVE
To confirm the accuracy and precision of transcutaneous bilirubin (TcB) values measured by a new device with two optical paths (JM-103) and the value of total serum bilirubin (TSB) level in clinical units of measurement.


METHODS
For comparison of the levels of accuracy and precision of JM-103 and the old device (JM-102), serum samples were collected from 77 Japanese infants in three different hospitals including 24 preterm infants and 53 term infants. Measurement of TcB by JM-103 and JM-102 were performed on the forehead of each infant within 30 min before or after blood sampling.


RESULTS
The range of TSB was limited to 19.6 mg/dL and to 17 mg/dL for preterm infants. The correlation coefficients for all subjects (r = 0.94) and for term and preterm subjects between TcB measured by JM-103 and TSB was higher than that between TcB measured by JM-102 and TSB. The regression line in term infants between TcB measured by JM-103 and TcB was similar to that in preterm infants. The error distribution of TcB measured by JM-102 and TSB for all subjects (0.00 +/- 2.21) and for term and preterm subjects was larger than that of TcB measured by JM-103 and TSB (all subjects, 0.30 +/- 1.55).
Yasuda
Saneyuki
S
Department of Pediatrics, Kagawa Medical University, Kagawa, Japan.
Itoh
Susumu
S
Isobe
Kenichi
K
Yonetani
Masahiko
M
Nakamura
Hajime
H
Nakamura
Makoto
M
Yamauchi
Yoshitada
Y
Yamanishi
Akio
A
D001663:Bilirubin / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D003116:Color; D004867:Equipment Design; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood; D007567:Jaundice, Neonatal / Q000175:diagnosis* / Q000378:metabolism; D015997:Neonatal Screening / Q000295:instrumentation*; D011237:Predictive Value of Tests; D012016:Reference Values; D012044:Regression Analysis; D040521:Subcutaneous Tissue / Q000378:metabolism*
D001663:Bilirubin