title: LEOPARD syndrome with a new association of congenital corneal tumor, choristoma.
abstract: A 5-year-old girl with a family history of LEOPARD syndrome had multiple lentigines on the face and trunk, hypertelorism, and growth retardation. In addition, she had congenital corneal tumors on both eyes. Histologically the tumors were choristoma. The neuroectodermal origin hypothesis of LEOPARD syndrome could explain the presence of a congenital corneal tumor in this patient. We suggest that corneal tumor may represent an unrecognized associated finding in this syndrome.
authors.affiliation: Department of Dermatology, College of Medicine, Seoul National University, Korea.
authors.forename: Won-Woo
authors.initials: WW
authors.lastname: Choi
authors.forename: Jong-Yeop
authors.initials: JY
authors.lastname: Yoo
authors.forename: Kyoung-Chan
authors.initials: KC
authors.lastname: Park
authors.forename: Kyu-Han
authors.initials: KH
authors.lastname: Kim
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis; D001707:Biopsy, Needle; D002675:Child, Preschool; D002828:Choristoma / Q000150:complications / Q000473:pathology*; D003315:Cornea; D005134:Eye Neoplasms / Q000150:complications / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000150:complications / Q000175:diagnosis; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000175:diagnosis; D006801:Humans; D006972:Hypertelorism / Q000150:complications / Q000175:diagnosis; D007150:Immunohistochemistry; D007911:Lentigo / Q000150:complications / Q000175:diagnosis; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D010375:Pedigree; D013577:Syndrome