[Digestive diseases and nutrition in cystic fibrosis].
Present in 85-90% of patients, pancreatic exocrine insufficiency contributes to growth retardation and delayed puberty in the child, and low weight in the adult. The incidence of hepatic disease varies according to whether one considers the discovery of histological abnormalities at autopsy of patients who have died from other complications (20-70%) or the presence of a focal or multilobular biliary cirrhosis complicated or not by portal hypertension (2-10%). Gastro-oesophageal reflux can contribute to the degradation of the nutritional state and exacerbate the respiratory symptomatology. All deviations of anthropometric parameters (weight/height ratio, body mass index) from standard references are a warning sign and justify nutritional assistance, of which one distinguishes 3 successive stages by chronological order: fractionated oral supplementation, nasogastric enteral nutrition and parenteral nutrition.
Turck
Dominique
D
Centre de soins pour la mucoviscidose, Unité de gastro-entérologie, hépatologie et nutrition Clinique de pédiatrie Hôpital Jeanne-de-Flandre, Faculté de médecine 59037 Lille. dturck@chru-lille.fr
Michaud
Laurent
L
Wizla-Derambure
Nathalie
N
D003550:Cystic Fibrosis / Q000150:complications* / Q000628:therapy; D004066:Digestive System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D009748:Nutrition Disorders / Q000209:etiology; D009747:Nutritional Physiological Phenomena