[Liver hemosiderosis in chronic hepatitis].
Liver hemosiderosis (LH) was studied in chronic hepatitis (CH) B and C and CH of other and alcoholic (AL) etiology. LH was present in 122 patients (a study group) and was absent in 188 patients (a comparison group). LH is considered to be a marker of organ iron overload. The total incidence of LH was 39.4 +/- 2.7%, including 33.3 +/- 5.6% in LH-B, 49.3 +/- 5.8% in LH-C, and 48.7 +/- 8.0% in AL. The association with LH was characterized by a longer duration of the disease, by a higher activity and degree of hepatic cirrhosis. The efficiency of reaferon therapy was lower in hepatitis B and C in the presence of LH. These forms of the disease are considered to be secondary hemosiderosis.
Smirnov
O A
OA
I.M. Mechnikov Saint-Petersburg State Medical Academy, 195067, Saint-Petersburg.
Anichkov
N M
NM
Radchenko
V G
VG
D006485:Hemosiderin / Q000032:analysis; D006486:Hemosiderosis / Q000209:etiology / Q000473:pathology*; D006521:Hepatitis, Chronic / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008099:Liver / Q000201:enzymology / Q000473:pathology*; D008103:Liver Cirrhosis / Q000209:etiology / Q000473:pathology; D008111:Liver Function Tests; D012074:Remission Induction
D007372:Interferons; D006485:Hemosiderin