Testicular blood flow alterations and flow cytometric analysis in prepubertal rats with experimentally induced unilateral varicocele.
Unilateral testicular pathologies have been accused of causing contralateral damage through a decrease in testicular blood flow. However, the contralateral testicular blood flow in unilateral varicocele has not been studied in detail. Therefore, the present study has been designed to evaluate the effects of a unilateral varicocele on the ipsilateral and on the contralateral testicular blood flow and the flow cytometric alterations in prepubertal rats. Experimental stenosis of the left renal vein in prepubertal rats causes dilation of the testicular vessels after puberty. Partial stenosis of the ipsilateral renal vein during the prepubertal period has no effect on ipsilateral or contralateral testicular blood flow, but does induce significant testicular damage, as determined by flow cytometry.
Oztürk
H
H
Department of Pediatric Surgery, Gülhane Military Medical Academy, Ankara, Turkey.
Surer
I
I
Okur
H
H
Demirbag
S
S
Cetinkursun
S
S
D000818:Animals; D001794:Blood Pressure; D005434:Flow Cytometry; D008026:Ligation; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012039:Regional Blood Flow; D012082:Renal Veins; D012741:Sexual Maturation / Q000502:physiology*; D013737:Testis / Q000098:blood supply* / Q000473:pathology; D014646:Varicocele / Q000473:pathology* / Q000503:physiopathology*