title: Recurrent bradycardia and delayed recovery in a neonate following repair of nasofrontal encephalocoele with holoprosencephaly and single cerebral ventricle.
abstract: Holoprosencephaly and single cerebral ventricle are uncommon congenital anomalies that are associated with a high rate of perinatal mortality. We describe a neonate who developed recurrent bradycardia along with delayed recovery following frontal craniotomy for the repair of a nasofrontal encephalocoele associated with holoprosencephaly and a single cerebral ventricle. The neonate, however, recovered following elective ventilation. Etiopathogenesis and management of such complications are discussed.
authors.affiliation: Department of Neuroanesthesiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. bhartineerja@rediffmail.com
authors.forename: Neerja
authors.initials: N
authors.lastname: Bharti
authors.forename: H H
authors.initials: HH
authors.lastname: Dash
authors.forename: A K
authors.initials: AK
authors.lastname: Mahapatra
mesh_terms: D000762:Anesthesia Recovery Period; D001919:Bradycardia / Q000209:etiology*; D002552:Cerebral Ventricles / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D003399:Craniotomy; D004677:Encephalocele / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016142:Holoprosencephaly / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures; D009666:Nose / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012121:Respiration, Artificial