Biologically active metabolites from fungi, 17. 8-alpha-acetoxyverrol, a new member of the trichothecene sesquiterpenes.
8-alpha-Acetoxyverrol (4), the first open chain example of the trichothecenes with oxygenation at C-8, was isolated from cultures of Aphanocladium spectabile. The compound doses the biosynthetic gap to the macrocyclic verrucarins.
Krohn
Karsten
K
Fachbereich Chemie und Chemietechnik der Universität Paderborn, Warburger Str. 100 D-33098 Paderborn, Germany.
Steingröver
Klaus
K
Aust
Hans-Jürgen
HJ
Draeger
Siegfried
S
Schulz
Barbara
B
D002850:Chromatography, Gel; D003904:Mitosporic Fungi / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014255:Trichothecenes / Q000737:chemistry / Q000302:isolation & purification*
D014255:Trichothecenes