title: [Corticosteroid therapy of acute viral myocarditis in patients with severe clinical course of disease].
abstract: The article is devoted to the issue of great current interest--that of treatment of patients with acute viral myocarditis. Topicality of the subject in touched upon in some detail, positive and negative sides of use of corticosteroids in patients with acute viral myocarditis are outlined. Comparative data are submitted of treatment of patients with acute viral myocarditis running a grave clinical course with heparin, thiotriasoline, complex heparin--thiotriasoline--prednisolone. The presented results of treatment show expediency of administration of corticosteroids leading to a statistically significant decrease in concentration of titres of antiviral antibodies Coxsackie B1-4 viruses, increase in ejection fraction, rises in platelet count in patients with acute viral myocarditis running a grave clinical course.
authors.forename: B H
authors.initials: BH
authors.lastname: Doroshenko
authors.forename: P S
authors.initials: PS
authors.lastname: Nazar
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000914:Antibodies, Viral / Q000032:analysis; D003384:Coxsackievirus Infections / Q000188:drug therapy*; D029822:Enterovirus B, Human / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D009205:Myocarditis / Q000188:drug therapy* / Q000821:virology; D011239:Prednisolone / Q000627:therapeutic use*; D012720:Severity of Illness Index
chemical_list: D000893:Anti-Inflammatory Agents; D000914:Antibodies, Viral; D011239:Prednisolone