title: Amyloidosis of medium-sized arteries presenting as perioral mass: a case report.
abstract: We report a case of amyloidosis localized to the medium-sized arteries of the face and presenting as prominent perioral swelling. The condition was identified as primary AL-type amyloidosis on the basis of immunohistochemical reactivity, predominantly for anti-lambda light chain antibody within amyloid deposits. Subsequent radiographic and laboratory evaluation of the patient disclosed multiple myeloma. Although amyloid deposits were subsequently detected in the temporal arteries, evidence of widespread amyloidosis has not been observed after 1 year of follow-up. To the best of our knowledge, this is the first report of myeloma-associated amyloidosis mainly localized to the medium-sized arteries of the face.
authors.affiliation: Taichung Veterans General Hospital, Department of Pathology, Taichung Kang Road, Section 3, No. 160, Taichung City 40705, Taiwan, Republic of China.
authors.forename: Mu-Chun
authors.initials: MC
authors.lastname: Li
authors.forename: Guan
authors.initials: G
authors.lastname: Chou
authors.forename: Jung-Ta
authors.initials: JT
authors.lastname: Chen
authors.forename: Yong Kie
authors.initials: YK
authors.lastname: Wong
authors.forename: William L
authors.initials: WL
authors.lastname: Ho
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis*; D001158:Arteries / Q000473:pathology; D003937:Diagnosis, Differential; D005145:Face / Q000098:blood supply*; D005500:Follow-Up Studies; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D007150:Immunohistochemistry; D008046:Lip / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000098:blood supply*; D009101:Multiple Myeloma / Q000175:diagnosis; D013699:Temporal Arteries / Q000473:pathology; D014652:Vascular Diseases / Q000175:diagnosis
chemical_list: D007146:Immunoglobulin lambda-Chains