title: Paradoxical effects of chemicals in the diet on health.
abstract: In 1992, Block et al. published a summary of 200 epidemiological investigations which indicated that a diet that was high in fruit and vegetables cut cancer risks approximately in half. These investigations used conventionally farmed produce that contained traces of synthetic pesticides and mycotoxins as well as an estimated 10,000 secondary products (i.e. natural pesticides). Dietary consumption of fruits and vegetables also reduces risks of cardiovascular disease, cataracts and brain dysfunction. Before genetic manipulation is undertaken to elevate or diminish any individual constituent of fruits and vegetables, the contribution of each of these constituents to health must be better understood, as in many cases their effects on health can be paradoxical.
authors.affiliation: Institute of Cell and Molecular Biology, Mayfield Road, University of Edinburgh, Edinburgh EH9 3JH, UK.
authors.forename: Anthony
authors.initials: A
authors.lastname: Trewavas
authors.forename: Derek
authors.initials: D
authors.lastname: Stewart
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology; D002273:Carcinogens / Q000008:administration & dosage / Q000633:toxicity; D003677:Deficiency Diseases; D004032:Diet; D005638:Fruit / Q000009:adverse effects / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D009183:Mycotoxins / Q000008:administration & dosage / Q000494:pharmacology / Q000633:toxicity; D010575:Pesticides / Q000009:adverse effects; D014675:Vegetables / Q000009:adverse effects / Q000737:chemistry* / Q000235:genetics
chemical_list: D000975:Antioxidants; D002273:Carcinogens; D009183:Mycotoxins; D010575:Pesticides