Kikuchi's disease accompanied by lupus-like butterfly rash.
Kikuchi's disease (KD) is a benign and self-limiting lymphadenitis, particularly affecting young women. KD is often associated with fever, arthralgia, and leukopenia, features also found in systemic lupus erythematosus (SLE). Lymphadenitis associated with SLE is indistinguishable from that in KD, and the association of KD and SLE has been previously reported. We describe a case of KD who developed a typical butterfly rash, reminiscent of SLE. However, histological and laboratory findings excluded the diagnosis of SLE. This case emphasizes that careful differential diagnosis between KD and SLE is required.
Okuzawa
Chie
C
Third Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Gunma, Japan.
Kuroiwa
Takashi
T
Kaneko
Yoriaki
Y
Ueki
Kazue
K
Tsukada
Yoshito
Y
Nojima
Yoshihisa
Y
D000293:Adolescent; D003937:Diagnosis, Differential; D005076:Exanthema / Q000175:diagnosis*; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000473:pathology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D008198:Lymph Nodes / Q000473:pathology