title: Single-trial estimation of multichannel evoked-potential measurements.
abstract: A method for single-trial estimation of multichannel evoked potentials is presented. The proposed method is based on the regularized least squares scheme. The spatial correlation between the channels is used as additional information in the estimation procedure. Amplitude estimates obtained with the proposed method is compared with the estimates calculated without using the spatial information. The performance of the method is evaluated using simulated and real data of P300 responses measured using auditory stimuli. The multichannel approach is shown to give realistic and comparable information about the amplitude differences of the P300 peak between different channels.
authors.affiliation: University of Kuopio, Department of Applied Physics, FIN-70211 Kuopio, Finland.
authors.forename: P O
authors.initials: PO
authors.lastname: Ranta-aho
authors.forename: A S
authors.initials: AS
authors.lastname: Koistinen
authors.forename: J O
authors.initials: JO
authors.lastname: Ollikainen
authors.forename: J P
authors.initials: JP
authors.lastname: Kaipio
authors.forename: J
authors.initials: J
authors.lastname: Partanen
authors.forename: Pasi A
authors.initials: PA
authors.lastname: Karjalainen
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000465:Algorithms; D001921:Brain / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D003198:Computer Simulation; D004569:Electroencephalography / Q000379:methods*; D005071:Evoked Potentials / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology; D008959:Models, Neurological; D015233:Models, Statistical; D011786:Quality Control; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D013269:Stochastic Processes