title: [Influence of dithranol therapy on clinical status and serum calcitonin concentrations in patients with common psoriasis].
abstract: The aim of this work was to study the effects of external dithranol therapy of psoriatic patients on the clinical status and serum calcitonin concentrations. This was done on 19 patients with common psoriasis using Cignoderm in the short contact therapy. Calcitonin concentration in serum samples was determined before and after a 14-day therapy. Results obtained before were compared with concentrations after dithranol treatment and with results in control group. Serum TSH was also measured in serum samples from both groups at the very beginning time. The determinations showed statistically significant lower serum TSH level in psoriatic patients before therapy vs. control and significant, negative correlation with calcitonin concentration in those patients. After a 14-day dithranol therapy a significant calcitonin concentration decrease as well as clinical effects were observed in the investigated group.
authors.affiliation: Kliniczny Oddział Dermatologii Szpitala Specjalistycznego, Zabrzu.
authors.forename: Witold
authors.initials: W
authors.lastname: Bendkowski
authors.forename: Ewa
authors.initials: E
authors.lastname: Hadas
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Swietochowska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Wielkoszyński
authors.forename: Zofia
authors.initials: Z
authors.lastname: Ostrowska
authors.forename: Bozena
authors.initials: B
authors.lastname: Szapska
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000875:Anthralin / Q000494:pharmacology / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002116:Calcitonin / Q000097:blood* / Q000187:drug effects*; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D002116:Calcitonin; D000875:Anthralin