title: Hepatic abscesses associated with umbilical catheterisation in two neonates.
abstract: We describe two neonates with a liver abscess after umbilical venous catheterisation. The first case was a female neonate, born at 32 weeks of gestation. After persistence of elevated inflammatory parameters, an abscess in the right lobe of the liver was diagnosed. Percutaneous drainage under CT guidance was performed. The aspirated pus grew Staphylococcus epidermidis. Inflammatory parameters normalised after 27 days of antimicrobial therapy (vancomycin, cefotaxim, rifampicin). The second case was in a male neonate, born at 29 weeks of gestation. Percutaneously aspirated pus from the liver abscess was cultured and remained sterile. The patient received antimicrobial therapy (vancomycin, cefotaxim, amikacin) for 26 days and was cured with conservative treatment.
  
  
  CONCLUSIONS
  hepatic abscess should be considered in any infant with an umbilical catheter-associated sepsis and persistent inflammatory response in spite of adequate antimicrobial therapy, especially when signs of abdominal infection are present.
authors.affiliation: Department of Paediatrics, Division of Neonatology, Faculty of Medicine, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium.
authors.forename: Els
authors.initials: E
authors.lastname: Moens
authors.forename: Jozef De
authors.initials: JD
authors.lastname: Dooy
authors.forename: Hilde
authors.initials: H
authors.lastname: Jansens
authors.forename: Christine
authors.initials: C
authors.lastname: Lammens
authors.forename: Bart
authors.initials: B
authors.lastname: Op de Beeck
authors.forename: Ludo
authors.initials: L
authors.lastname: Mahieu
mesh_terms: D002406:Catheterization, Peripheral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008100:Liver Abscess / Q000209:etiology* / Q000382:microbiology; D008297:Male; D013203:Staphylococcal Infections / Q000209:etiology*; D013212:Staphylococcus epidermidis; D014471:Umbilical Veins