title: [Life-threatening theophylline intoxication: a variant of Munchhausen syndrome by proxy].
abstract: We report of a prematurely born infant, who was admitted to hospital at the age of 6 months due to seizures. The seizures continued despite of an improved electroencephalogram due to varying medications. The boy had episodes of hypokaliaemia, diarrhea, and tachycardia which were treated in critical care unit. Not before 3 months of continued treatment and diagnostic work up in three different hospitals had passed the underlying poisoning with theophylline by the mother was proved. The toxicity of theophylline is well known. Adverse reactions occur frequently during theophylline therapy. There are numerous reports of suicidal intoxications with theophylline. Non-accidental poisoning with theophylline has not yet been reported in the context of Munchausen syndrome by proxy.
authors.affiliation: Abteilung für allgemeine Kinderheilkunde, Klinik und Poliklinik für Kinderheilkunde, Universitätsklinikum Münster. dfoell@uni-muenster.de
authors.forename: D
authors.initials: D
authors.lastname: Föll
authors.forename: O
authors.initials: O
authors.lastname: Debus
authors.forename: G M
authors.initials: GM
authors.lastname: Schmitt
authors.forename: E
authors.initials: E
authors.lastname: Harms
authors.forename: K-P
authors.initials: KP
authors.lastname: Zimmer
mesh_terms: D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000187:drug effects; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced / Q000175:diagnosis; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008297:Male; D016735:Munchausen Syndrome by Proxy / Q000175:diagnosis* / Q000523:psychology; D011041:Poisoning / Q000175:diagnosis*; D013036:Spasms, Infantile / Q000139:chemically induced / Q000175:diagnosis; D013610:Tachycardia / Q000139:chemically induced / Q000175:diagnosis; D013806:Theophylline / Q000506:poisoning*
chemical_list: D013806:Theophylline