title: Left ventricular systolic dysfunction and ischemic cardiomyopathy.
abstract: Coronary artery disease is the primary risk factor for left ventricular systolic dysfunction and the most common cause of heart failure. Heart failure is the prevailing diagnosis for hospital admissions in the United States for people over 65 years of age. It has a great impact on the health care delivery system as a whole for both inpatient and outpatient treatment. A comprehensive understanding of this disease state is paramount for health care providers. This article describes the epidemiology, risk factors, pathophysiology, and current treatment modalities for left ventricular systolic dysfunction related to heart disease.
authors.affiliation: The Cardiovascular Institute, The University of Pittsburgh Medical Center, Pittsburgh, Pa, USA. Henrlm@msn.upmc.edu
authors.forename: Lisa Bratton
authors.initials: LB
authors.lastname: Henry
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003327:Coronary Disease / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D012307:Risk Factors; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D002317:Cardiovascular Agents