Clinical spectrum of Swyer-James-Macleod syndrome in adults.
OBJECTIVE
The aim of this study is to describe the clinical and imaging features of Swyer-James-Macleod syndrome (SJMS) in 9 adults.


METHODS
We reviewed the charts of 9 patients diagnosed with SJMS at the King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia over a 10 year period.


RESULTS
The patients mean age was 38.1 years; males were more affected than females (7:2). Seven of the patients had symptoms referable to the chest and a similar number had compatible abnormalities on physical examination. The left lung was involved in all cases. Bronchiectasis was present in 7 (77.8%). Eight patients who underwent pulmonary function tests had combined defects. Two patients demonstrated significant reversibility. All patients had a stable course over at least before a 3 year follow-up period.


CONCLUSIONS
Swyer-James-Macleod syndrome has a diverse manifestations in adults and can mimic other pulmonary disorders, which may lead to incorrect diagnosis and inappropriate therapy. The course is generally a stable one.
Abba
Abdullah A
AA
Department of Medicine, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh 11533, Kingdom of Saudi Arabia. abbaiya@yahoo.com
Al-Mobeireek
Abdullah F
AF
D000328:Adult; D001987:Bronchiectasis / Q000175:diagnosis; D005260:Female; D006801:Humans; D019568:Lung, Hyperlucent / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014692:Ventilation-Perfusion Ratio