Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru.
Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (n = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.
Ahmed
Niyaz
N
Centre for DNA Fingerprinting and Diagnostics (CDFD), Nacharam, Hyderabad 500076, India.
Caviedes
Luz
L
Alam
Mahfooz
M
Rao
K Rajender
KR
Sangal
Vartul
V
Sheen
Patricia
P
Gilman
Robert H
RH
Hasnain
Seyed E
SE
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D016172:DNA Fingerprinting / Q000379:methods; D005838:Genotype; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D010568:Peru; D010802:Phylogeny; D012150:Polymorphism, Restriction Fragment Length; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000382:microbiology*