Evidence of inter- and intra-molecular crosslinking of tyrosine residues of calmodulin induced by photo-activation of ruthenium(II).
Tris(2,2'-bipyridyl)ruthenium(n) upon illumination with light at a wavelength of 450 nm in the presence of an electron acceptor induces dityrosine crosslinking in proteins.
Andreev
Oleg A
OA
Department of Molecular Biology and Immunology, Institute for Cancer Research, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Blvd, Fort Worth, TX 7610, USA. oandreev@hsc.unt.edu
Reshetnyak
Yana K
YK
Goldfarb
Ronald H
RH
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives* / Q000737:chemistry / Q000528:radiation effects; D000818:Animals; D002147:Calmodulin / Q000737:chemistry*; D002417:Cattle; D056831:Coordination Complexes; D010777:Photochemistry; D011506:Proteins / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry* / Q000528:radiation effects; D013050:Spectrometry, Fluorescence; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry*; D017975:Ruthenium Compounds
D015082:2,2'-Dipyridyl; D002147:Calmodulin; D056831:Coordination Complexes; D011506:Proteins; D012428:Ruthenium; D014443:Tyrosine; C547232:tris(2,2-bipyridine)-ruthenium(II); D017975:Ruthenium Compounds; C007543:dityrosine