Dermatofibrosarcoma protuberans of breast.
We describe the case of a 57-year-old woman with a tumor of the breast suspected of being a dermatofibrosarcoma protuberans (DFSP). To confirm the diagnosis, molecular studies were performed on fixed tumor and revealed the presence of the fusion product of the COL1A1-PDGFB genes characteristic of DFSP.
Sandberg
Avery A
AA
Department of DNA Diagnostics, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013, USA. jvaugha@chw.edu
Anderson
William D
WD
Fredenberg
Christine
C
Hashimoto
Hiroshi
H
D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D024042:Collagen Type I / Q000235:genetics; D000090602:Collagen Type I, alpha 1 Chain; D018223:Dermatofibrosarcoma / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D005091:Exons; D005260:Female; D006801:Humans; D008875:Middle Aged; D015514:Oncogene Proteins, Fusion / Q000235:genetics; D020797:Receptor, Platelet-Derived Growth Factor beta / Q000235:genetics; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology* / Q000601:surgery
D024042:Collagen Type I; D000090602:Collagen Type I, alpha 1 Chain; D015514:Oncogene Proteins, Fusion; D020797:Receptor, Platelet-Derived Growth Factor beta