Apoptosis in peripheral blood leukocytes induced by hyperthermia and prednisolone in patients with dysadaptation.
We studied morphological changes in blood leukocytes produced by prednisolone and hyperthermia. Patients with dysadaptation were characterized by activation of spontaneous apoptosis and inhibition of induced apoptosis in neutrophils and lymphocytes compared to healthy donors.
Chernykh
E I
EI
Research Institute for Mental Health, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Russia. lenccher@mail.ru
Yazykov
K G
KG
Semke
V Ya
VY
D000222:Adaptation, Physiological; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects* / Q000502:physiology*; D005260:Female; D005334:Fever; D006801:Humans; D007962:Leukocytes / Q000187:drug effects*; D008297:Male; D009504:Neutrophils / Q000187:drug effects; D011239:Prednisolone / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D011239:Prednisolone