Synthesis of alpha,alpha-dibromo esters as precursors of ynolates.
Aliphatic alpha,alpha-dibromo esters, precursors of ynolates, were synthesized via bromination of lithium alpha-bromo ester enolates with 1,2-dibromotetrafluoroethane in good yields. alpha-Trimethylsilyl-alpha,alpha-dibromo esters were synthesized via radical bromination.
Shindo
Mitsuru
M
Institute for Medicinal Resources, University of Tokushima, 1 Sho-machi, Japan. shindo@ph2.tokushima-u.ac.jp
Sato
Yusuke
Y
Koretsune
Ryoko
R
Yoshikawa
Takashi
T
Matsumoto
Kenji
K
Itoh
Kotaro
K
Shishido
Kozo
K
D001557:Benzenesulfonates / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters
D001557:Benzenesulfonates; D004952:Esters; C012890:alpha,alpha-dibromo-4-xylenesulfonic acid