title: Intracranial hemorrhage in late hemorrhagic disease of the newborn.
abstract: This study was conducted to evaluate the clinical profile and outcome in late hemorrhagic disease of the newborn (HDN) with particular reference to intracranial hemorrhage. Infants (n = 42) presenting with late HDN from January 1998 to December 2001 were studied. Majority (76%) were in the age group of 1-3 months. All were term babies on exclusive breast-feeding and none received vitamin K at birth. 71% patients presented with intracranial hemorrhage, commonest site being intracerebral and multiple ICH. Visible external bleeding was noted in 1/3rd of patients only. Three patients expired. Late HDN is still an important cause of mortality and morbidity in developing countries where vitamin K prophylaxis is not routinely practiced. Isolated intracranial hemorrhage is a common mode of presentation.
authors.affiliation: Department of Pediatrics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. poonia@yahoo.com
authors.forename: Puneet A
authors.initials: PA
authors.lastname: Pooni
authors.forename: Daljit
authors.initials: D
authors.lastname: Singh
authors.forename: Harmesh
authors.initials: H
authors.lastname: Singh
authors.forename: B K
authors.initials: BK
authors.lastname: Jain
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D017063:Outcome Assessment, Health Care; D012307:Risk Factors; D013997:Time Factors; D006475:Vitamin K Deficiency Bleeding / Q000150:complications* / Q000175:diagnosis / Q000628:therapy