Using Tc-99m DMSA renal scan to detect renal damage in Taiwanese women with Type 2 diabetes--a preliminary report.
In this preliminary study, we compared control women and Type 2 diabetes mellitus (DM) women for the prevalence and type of renal damage as revealed by technetium-99m dimercapto-succinic acid (Tc-99m DMSA) renal scan.


METHODS
A total of 20 control women and 60 women with Type 2 DM received Tc-99m DMSA renal scan were included in this study. The 60 women with Type 2 DM were separated into three groups: 20 women without UTI history, 20 patients with cystitis histories only, and 20 with pyelonephritis histories.


RESULTS
All of the control women had normal Tc-99m DMSA renal scan findings. However, 38.3% of Type 2 DM wonmen had abnormal Tc-99m DMSA renal scan findings. Type 2 DM women without UTI history had no abnormal scan findings. The prevalence of abnormal renal scan findings was significantly higher in Type 2 DM women with pyelonephritis (90.0%) than with cystitis alone (25.0%). Renal scar findings were found only in Type 2 DM women with pyelonephritis (40.0%).


CONCLUSIONS
Compared with control women, women with Type 2 DM, especially if they had UTI and pyelonephritis histories, have a significantly higher prevalence of abnormal Tc-99m DMSA renal scan findings.
Chang
Chao-Hsiang
CH
Department of Urology, China Medical College Hospital, Taichung, Taiwan.
Shiau
Yu-Chien
YC
Lin
Cheng-Chieh
CC
Kao
Chia-Hung
CH
Hsu
Chung-Huei
CH
D016022:Case-Control Studies; D002921:Cicatrix / Q000000981:diagnostic imaging; D003556:Cystitis / Q000000981:diagnostic imaging; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000000981:diagnostic imaging* / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011704:Pyelonephritis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
D019783:Technetium Tc 99m Dimercaptosuccinic Acid