title: [Twenty-four cases of carcinoma in pleomorphic adenoma in the salivary gland].
abstract: OBJECTIVE
  To study the clinical characteristics, treatment and prognosis 24 cases of carcinoma in pleomorphic adenoma in salivary gland.
  
  
  METHODS
  The clinical data of 24 patients with carcinoma in pleomorphic adenoma treated in our hospital from September 1974 to July 1995 were analyzed.
  
  
  RESULTS
  The overall 5-year survival rate was 66.7%. The five-year survival rates of patients with carcinoma in pleomorphic adenoma in the major and minor salivary glands were 63.6% and 2/2, respectively.
  
  
  CONCLUSIONS
  Operation is the optimal treatment and extensive resection at the initial operation is suggested. For lumps in the submaxillary gland, preventive neck dissection should be considered. Postoperative radiotherapy can not improve the local-control rate.
authors.affiliation: Department of Head & Neck Surgery, Cancer Hospital, FuDan University, Shanghai 200032, China.
authors.forename: Cai-ping
authors.initials: CP
authors.lastname: Huang
authors.forename: Hong-shi
authors.initials: HS
authors.lastname: Wang
authors.forename: Xiao-yu
authors.initials: XY
authors.lastname: Tu
mesh_terms: D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012468:Salivary Gland Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D015996:Survival Rate