title: Implementation of the three Rs in regulatory testing of vaccines in Canada.
authors.affiliation: Vaccines Division, Bureau of Biologics and Radiopharmaceuticals, Biologics and Genetic Therapies Directorate, Health Canada, Ottawa, Ont.
authors.forename: G A
authors.initials: GA
authors.lastname: Calver
mesh_terms: D000826:Animal Testing Alternatives; D000818:Animals; D002170:Canada; D066298:In Vitro Techniques; D012107:Research Design; D018675:Toxicity Tests / Q000379:methods*; D014612:Vaccines / Q000633:toxicity*
chemical_list: D014612:Vaccines