First example of electrophile induced Baylis-Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives.
Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis-Hillman reaction.
Basavaiah
Deevi
D
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. dbsc@uohyd.ernet.in
Rao
Anumolu Jaganmohan
AJ