[The distribution and detection of androgen receptor in extra-testis tissues].
Androgen receptor(AR) plays an important role in modulating the effects of androgen on target cells. It is well known that AR is mainly existed in testis. This paper reviewed the distribution of AR and its mRNA in prostate, epididymis, skin of penis, and some other tissues in non-genital system and tumors, such as the skin of scalp, hippocampus, fat, gastric cancer, cancer of larynx, and so on. Besides, this paper also reviewed the detection methods to AR, and further investigated the function of androgen.
Cheh
Lei-Lei
LL
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Yao
Bing
B
Huang
Yu-Feng
YF
D000728:Androgens / Q000378:metabolism; D006624:Hippocampus / Q000378:metabolism; D006801:Humans; D008297:Male; D010413:Penis / Q000378:metabolism*; D011467:Prostate / Q000378:metabolism*; D011944:Receptors, Androgen / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*; D014018:Tissue Distribution; D014407:Tumor Cells, Cultured
D000728:Androgens; D011944:Receptors, Androgen