title: [Experimental study of vasoligation in the treatment and prevention of benign prostatic hyperplasia].
abstract: OBJECTIVE
  To investigate the possibility and efficacy of vasoligation and deferent vein ligation in treating and preventing benign prostatic hyperplasia(BPH).
  
  
  METHODS
  40 male pooches were divided into A, B, C and D groups randomly. Each group has 10 pooches group A and B were made into the model of BPH. Two years later, the pooches in group A and C accepted the operation of vasoligation and deferent vein ligation on both sides. Group B and D only accepted the operation of dissection and relieving its deferent duct. Then continuing to feed the 40 pooches after the operation, they were killed another two years later. After taking out their prostates and calculating their volume and weight, the sections of the prostates were checked by microscope to observe their histology and pathology changes.
  
  
  RESULTS
  There were significant differences of weight and volume as well as the changes of histology and pathology between group A and group C (P < 0.01). It was the same with group B and D (hyperplasia changes).
  
  
  CONCLUSIONS
  Vasoligation and deferent vein ligation before benign prostatic hyperplasia at pooches grow-up stage can reduce the extent of BPH at old age, and treatment after benign prostatic hyperplasia can make prostatic tissue appear different degrees of atrophy.
authors.affiliation: Institute of Andrology, Medical College, Three Gorges University, Yichang, Hubei 443003, China.
authors.forename: Xian-Kun
authors.initials: XK
authors.lastname: Guo
authors.forename: Jiang
authors.initials: J
authors.lastname: Bian
authors.forename: Yong
authors.initials: Y
authors.lastname: Nie
authors.forename: Zhao-Xiang
authors.initials: ZX
authors.lastname: Zhang
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wu-Yang
authors.initials: WY
authors.lastname: Gao
authors.forename: Yong-Ju
authors.initials: YJ
authors.lastname: Feng
authors.forename: Shi-Ping
authors.initials: SP
authors.lastname: Cheng
authors.forename: Yan-Jiu
authors.initials: YJ
authors.lastname: Xiang
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D008026:Ligation; D008297:Male; D011470:Prostatic Hyperplasia / Q000517:prevention & control / Q000628:therapy*; D014659:Vasectomy