Bone mineral density in a cohort of adolescent women using depot medroxyprogesterone acetate for one to two years.
The purpose of this study was to examine estradiol and bone mineral density (BMD) in a cohort of adolescents using depot medroxyprogesterone acetate (DMPA) for one to two years. BMD was significantly decreased in the femoral neck and lumbar spine at year one. Estradiol levels suggested hypoestrogenization among subjects
Busen
Nancy H
NH
University of Texas Houston Health Science Center, School of Nursing, Houston, Texas 77030, USA. nbusen@son1.nur.uth.tmc.edu
Britt
Robin B
RB
Rianon
Nahid
N
D015502:Absorptiometry, Photon; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D015519:Bone Density / Q000187:drug effects* / Q000502:physiology; D015331:Cohort Studies; D003271:Contraceptive Agents, Female; D004334:Drug Administration Schedule; D004958:Estradiol / Q000032:analysis*; D005260:Female; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage*; D011446:Prospective Studies; D012016:Reference Values
D003271:Contraceptive Agents, Female; D004958:Estradiol; D017258:Medroxyprogesterone Acetate