title: Carotid endarterectomy in the octogenarian: outcomes of 345 procedures performed from 1995-2000.
abstract: The purpose of this study is to evaluate the efficacy and the safety of carotid endarterectomy (CEA) in the octogenarian patient. From January 1995 to December 2000, we have performed 3430 CEAs in 2743 patients: 345 CEAs in 269 octogenarian patients (Group 1) and 3085 CEAs in 2474 younger patients (Group 2). Age was the only selection criteria for including patients in Group 1. Octogenarians' perioperative mortality (1.4%) was greater than that in Group 2 (0.3%) (p<0.05). No differences can be found between the groups' perioperative ipsilateral stroke rates (1.7% in Group 1 vs 1.2% in Group 2) and combined ipsilateral stroke and death rates (2.3% in Group 1 vs 1.3% in Group 2) (p>0.05). The octogenarians' Kaplan-Meier 6-year overall and free-stroke survival rates were 86 and 76% respectively. CEA can be performed in selected octogenarian patients with low early and late mortality and neurologic morbidity rates.
authors.affiliation: Department of Vascular Surgery, Scientific Institute (IRCCS), H. San Raffaele, Università "Vita e salute" San Raffaele, Via Olgettina, 60-20132, Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Pruner
authors.forename: R
authors.initials: R
authors.lastname: Castellano
authors.forename: A M
authors.initials: AM
authors.lastname: Jannello Am
authors.forename: D
authors.initials: D
authors.lastname: Astore
authors.forename: E
authors.initials: E
authors.lastname: Civilini
authors.forename: G
authors.initials: G
authors.lastname: Melissano
authors.forename: R
authors.initials: R
authors.lastname: Chiesa
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D016894:Endarterectomy, Carotid / Q000009:adverse effects* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D020521:Stroke / Q000517:prevention & control; D015996:Survival Rate; D016896:Treatment Outcome