CD8 T-cell memory: the other half of the story.
Historically, most immune response studies have been limited to analyses of lymphoid tissue. However, peripheral sites of infection are likely to represent important sites of cell-mediated immune surveillance and effector function. Recent debates have centered on the persistence, trafficking patterns, effector activity, and protective role of non-lymphoid memory T cells.
Masopust
David
D
Division of Immunology, Department of Medicine, University of Connecticut Health Center, 263 Farmington Avenue, MC1319, Farmington, CT 06030-1319, USA.
Lefrançois
Leo
L
D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D002465:Cell Movement; D006801:Humans; D007156:Immunologic Memory; D007239:Infections / Q000276:immunology*; D007413:Intestinal Mucosa / Q000276:immunology; D008099:Liver / Q000276:immunology; D008168:Lung / Q000276:immunology; D051379:Mice