166Ho-coated balloon for vascular brachytherapy.
A simple procedure was developed for coating the surface of a conventional percutaneous transluminal coronary angioplasty balloon angioplasty catheter with 166Ho. The absorbed dose delivered by the surface-coated catheter is twice that of a similar catheter filled with a solution containing the same activity of 166Ho. Leakage tests show that <0.6% of the coated activity is removable from the surface of the catheter. The coated catheter removes the risk of release of the 166Ho into the body as a result of rupture of the balloon, and also reduces the radiation exposure to staff.
Hong
Young-Don
YD
RI and Radiation Application Team, Korea Atomic Energy Research Institute, 150, Dukjin-dong Yuseong-gu, 305-353, Daejon, South Korea.
Choi
Sun-Ju
SJ
Kim
Kyung-Hwa
KH
Shin
Byung-Chul
BC
Park
Woong-Woo
WW
Park
Sang-Hyun
SH
Park
Kyung Bae
KB
D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D001918:Brachytherapy / Q000379:methods*; D003327:Coronary Disease / Q000532:radiotherapy; D006695:Holmium / Q000008:administration & dosage* / Q000737:chemistry*; D006801:Humans; D011834:Radiation Monitoring; D011835:Radiation Protection; D011868:Radioisotopes / Q000008:administration & dosage* / Q000737:chemistry* / Q000493:pharmacokinetics; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics; D011879:Radiotherapy Dosage; D013997:Time Factors
D011868:Radioisotopes; D019275:Radiopharmaceuticals; D006695:Holmium