title: Allergy to chlorhexidine gluconate in urethral gel: report of four cases and review of the literature.
abstract: Chlorhexidine is a bis-biguanide molecule widely used in many preparations as a disinfectant and an antiseptic. We describe four confirmed cases of allergy to chlorhexidine gluconate in urethral gel and review the existing published reports. Pertinent issues in the treatment and investigation of these patients are discussed.
authors.affiliation: Department of Urology, Hawke's Bay Hospital, Hastings, New Zealand.
authors.forename: Anuradha
authors.initials: A
authors.lastname: Jayathillake
authors.forename: David F C
authors.initials: DF
authors.lastname: Mason
authors.forename: Kim
authors.initials: K
authors.lastname: Broome
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D002710:Chlorhexidine / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000209:etiology*; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D014546:Urinary Catheterization / Q000009:adverse effects / Q000379:methods*
chemical_list: D000892:Anti-Infective Agents, Urinary; D005782:Gels; C010882:chlorhexidine gluconate; D002710:Chlorhexidine