Oral cancer research with an emphasis on genomic analysis.
Ablative surgery has been a standard procedure for many years, but during the past few years there has been a significant improvement in our understanding of invasion and metastasis in oral cancer. Each procedure has to be planned individually. Before surgery, every attempt must have been made to arrive at a proper diagnosis, including the exact nature and aggressiveness of the tumor and an analysis of the patient's genetic background. These procedures and the prognosis will be discussed.
Shibahara
Takahiko
T
First Department of Oral and Maxillofacial Surgery, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan.
Noma
Hiroyasu
H
Kakizawa
Takashi
T
Ohtsuru
Hiroshi
H
Fukutake
Kimio
K
Uchida
Ikuhiro
I
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D016147:Genes, Tumor Suppressor; D006801:Humans; D015994:Incidence; D008297:Male; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D020411:Oligonucleotide Array Sequence Analysis; D012744:Sex Ratio
D004273:DNA, Neoplasm