title: Luteinizing hormone following light exposure in healthy young men.
abstract: Urinary luteinizing hormone (LH) and the melatonin metabolite (6-sulfatoxymelatonin; aMT6s) were measured in normal young men following early morning light exposure. Eleven young healthy men ages 19-30 years participated in this study. During separate weeks in counterbalanced order, each subject received both 5 days of bright light treatment (BL) and 5 days of placebo light treatment (PL) for 1 h (05:00-06:00). LH excretion was increased 69.5% after bright light exposure, but was not changed by placebo light exposure. The acrophases and offsets of aMT6s were advanced, but the duration of aMT6s excretion was not changed after BL. Light stimulation of LH could have interesting applications in psychiatry and reproductive endocrinology.
authors.affiliation: Department of Psychiatry and Sam and Rose Stein, Institute for Research on Aging, 0667, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA 92093-0667, USA.
authors.forename: In-Young
authors.initials: IY
authors.lastname: Yoon
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Kripke
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Elliott
authors.forename: Shawn D
authors.initials: SD
authors.lastname: Youngstedt
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D018592:Cross-Over Studies; D006801:Humans; D008029:Lighting / Q000379:methods*; D007986:Luteinizing Hormone / Q000652:urine*; D008297:Male; D008550:Melatonin / Q000031:analogs & derivatives* / Q000652:urine; D010775:Photic Stimulation / Q000379:methods; D017440:Photoperiod
chemical_list: C054513:6-sulfatoxymelatonin; D007986:Luteinizing Hormone; D008550:Melatonin