title: [Changes of prostaglandin E2 levels in periapical exudates after root canal treatment].
abstract: OBJECTIVE
  The aim of this study was to examine the levels of prostaglandin E2 in periapical exudates before and after root canal treatment.
  
  
  METHODS
  Periapical exudates specimens were quantitatively sampled from root canals of 25 teeth at consecutive treatment visits, and the concentration of prostaglandin E2 in each sample was determined using a commercial kit.
  
  
  RESULTS
  The mean prostaglandin E2 levels significantly decreased after the endodontic therapy. Significant correlations between the levels of prostaglandin E2 and the clinical features of periapical periodontitis were also found in this study.
  
  
  CONCLUSIONS
  The results suggest that the level of prostaglandin E2 in periapical exudates reflects the state of periapical periodontitis.
authors.affiliation: Department of Endodontics, Stomatological College, Nanjing Medical University, Nanjing 210029, China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Liu
authors.forename: Jinhua
authors.initials: J
authors.lastname: Yu
authors.forename: Hongbo
authors.initials: H
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015232:Dinoprostone / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010485:Periapical Periodontitis / Q000378:metabolism* / Q000628:therapy; D010490:Pericardial Effusion / Q000378:metabolism*; D011671:Pulpitis / Q000378:metabolism / Q000628:therapy; D012390:Root Canal Therapy
chemical_list: D015232:Dinoprostone