title: Thermodynamic characterization of ferric and ferrous haem binding to a designed four-alpha-helix protein.
abstract: The thermodynamics of ferric and ferrous haem affinity of a de novo designed four-alpha-helix bundle protein and the associated haem electrochemistry is described.
authors.affiliation: Columbia University, Department of Chemistry, 3000 Broadway MC 3121, New York, NY 10027, USA.
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Reedy
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Kennedy
authors.forename: Brian R
authors.initials: BR
authors.lastname: Gibney
mesh_terms: D004563:Electrochemistry; D005290:Ferric Compounds / Q000378:metabolism*; D005296:Ferrous Compounds / Q000378:metabolism*; D006418:Heme / Q000737:chemistry* / Q000378:metabolism*; D010084:Oxidation-Reduction; D011485:Protein Binding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics; D017186:Titrimetry / Q000379:methods
chemical_list: D005290:Ferric Compounds; D005296:Ferrous Compounds; D011506:Proteins; D006418:Heme