title: [A comparative study of digital colposcope and optical colposcope in the diagnosis of early lesions of uterine cervix].
abstract: OBJECTIVE
  To evaluate the clinical value of domestically manufactured digital colposcope system (SLC-2000) in the detection of early cervical lesions.
  
  
  METHODS
  During a follow-up study of patients in Xiangyuan county, Shanxi, a high risk area for cervical cancer, a digital colposcope and an optical colposcope were randomly used for diagnosis, with pathology as the gold standard.
  
  
  RESULTS
  In 163 cervical biopsy specimens, 103 were diagnosed as chronic inflammation by histologic examination. Among 60 specimens which gave abnormal pathology, there were papilloma 1, cervical intra-epithelial neoplasia (CIN) I 37, CIN II 18 and CIN III 4. In 33 endocervical curettage specimens, 3 were pathologically positive. Comparing the digital and optical colposcope in diagnosing the positive lesions of > or = CIN I, the sensitivity of the former and latter were 83.3% and 95.0%, the difference without being statistically significant (P = 0.075). The specificity, positive predictive value, and accuracy of these two instruments were 61.2%, 21.4%, 55.6% and 41.3%, 69.3% 48.5%, with significant difference (P = 0.000, P = 0.035, and P = 0.000). In diagnosing > or = CIN II cervical lesions, these three results of the two instruments did not show any significant difference either. The negative predictive value of the digital and optical colposcope were 86.3% and 88.0%, also showing no significant difference (P = 0.075).
  
  
  CONCLUSIONS
  The specificity, positive predictive value, and accuracy of the digital colposcope in diagnosing cervical lesions > or = CIN I are all superior to those of the traditional optical colposcope, even though the sensitivity of the latter is higher. There is no difference between the two instruments in diagnosing lesions > or = CIN II. Not only is domestic digital colposcope (SLC-2000) effective, but feasible and practical in the diagnosis, research and follow-up of cervical lesions.
authors.affiliation: Department of Gynecologic Oncology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zhang
authors.forename: Manni
authors.initials: M
authors.lastname: Huang
authors.forename: Shumin
authors.initials: S
authors.lastname: Li
authors.forename: Lingying
authors.initials: L
authors.lastname: Wu
authors.forename: Nan
authors.initials: N
authors.lastname: Li
authors.forename: Xun
authors.initials: X
authors.lastname: Zhang
authors.forename: Qinjing
authors.initials: Q
authors.lastname: Pan
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Shen
authors.forename: Youlin
authors.initials: Y
authors.lastname: Qiao
mesh_terms: D020681:Colposcopes; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D002577:Uterine Cervical Diseases / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis; D002575:Uterine Cervicitis / Q000175:diagnosis