title: Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates.
abstract: A young woman with transient osteoporosis of the hip (TOH) during pregnancy, severe pain, physical disability and marked generalized osteoporosis was treated with intravenous biphosphonates with prompt beneficial effects on both clinical symptoms and bone density. The features of this rare and sometimes underdiagnosed condition are reviewed. Intravenous biphosphonates seem to be an effective therapy for TOH.
authors.affiliation: B. Shine Department of Rheumatology, Rambam Medical Center, Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Schapira
authors.forename: Y
authors.initials: Y
authors.lastname: Braun Moscovici
authors.forename: G
authors.initials: G
authors.lastname: Gutierrez
authors.forename: A M
authors.initials: AM
authors.lastname: Nahir
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D000963:Antimetabolites / Q000627:therapeutic use*; D001175:Arthrography; D015519:Bone Density / Q000187:drug effects; D004002:Clodronic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007275:Injections, Intravenous; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology; D010024:Osteoporosis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D018712:Analgesics, Non-Narcotic; D000963:Antimetabolites; D004002:Clodronic Acid