title: Orthokeratology lens-related Pseudomonas aeruginosa infectious keratitis.
abstract: OBJECTIVE
  To report a case of orthokeratology lens-related Pseudomonas corneal ulcer in an adult.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 37-year-old man presented with a 1-day history of painful red eye. He was a soft contact lens wearer before he started on nocturnal orthokeratology lens wear of 8 to 10 hours per night 9 months ago. Corneal scraping sent for culture revealed a heavy growth of Pseudomonas aeruginosa. The patient was treated with intensive topical fortified tobramycin and ceftazidime drops. The ulcer healed with a residual paraxial corneal scar. Although his best-corrected visual acuity (BCVA) recovered from finger counting (8/200) at presentation to 20/30, he suffered visual loss from a premorbid BSCVA of 20/15. His contrast sensitivity (Vector Vision CSV 1000 test) performance was also worse than his fellow eye.
  
  
  CONCLUSIONS
  Nocturnal orthokeratology lens wear may be associated with an increased risk of infection.
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, People's Republic of China.
authors.forename: Alvin L
authors.initials: AL
authors.lastname: Young
authors.forename: Alfred T S
authors.initials: AT
authors.lastname: Leung
authors.forename: Eva Y Y
authors.initials: EY
authors.lastname: Cheung
authors.forename: Lulu L
authors.initials: LL
authors.lastname: Cheng
authors.forename: Angus K K
authors.initials: AK
authors.lastname: Wong
authors.forename: Dennis S C
authors.initials: DS
authors.lastname: Lam
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D009216:Myopia / Q000628:therapy; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D014031:Tobramycin / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D002442:Ceftazidime; D014031:Tobramycin