title: Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue.
authors.affiliation: Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital, Boston, MA.
authors.forename: Sean P
authors.initials: SP
authors.lastname: Colgan
authors.forename: Cormac T
authors.initials: CT
authors.lastname: Taylor
authors.forename: Sailaja
authors.initials: S
authors.lastname: Narravula
authors.forename: Kristin
authors.initials: K
authors.lastname: Synnestvedt
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Blume
mesh_terms: D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism*; D001483:Base Sequence; D015687:Cell Hypoxia / Q000502:physiology*; D002460:Cell Line; D018920:Coculture Techniques; D051546:Cyclooxygenase 2; D017931:DNA Primers; D004730:Endothelium, Vascular / Q000201:enzymology*; D004790:Enzyme Induction; D004847:Epithelial Cells / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis / Q000235:genetics*; D008565:Membrane Proteins; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis / Q000235:genetics*; D020545:Respiratory Mucosa / Q000502:physiology; D014471:Umbilical Veins; D019459:Urothelium / Q000502:physiology
chemical_list: D017931:DNA Primers; D007527:Isoenzymes; D008565:Membrane Proteins; D015121:6-Ketoprostaglandin F1 alpha; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases