Renal alterations promoted by the lectins from Canavalia ensiformis (ConA) and Dioclea guianensis (DguiL) seeds.
The lectin from the seeds of Canavalia ensiformis (ConA) and Dioclea guianensis (DguiL) was tested upon its renal effects using the isolated perfusion rat kidney method. Both lectins (10 microg/ml) affected perfusion pressure and renal vascular resistance, but DguiL showed a much greater action than ConA. However, ConA, but not DguiL, affected potassium tubular transport.
Havt
Alexandre
A
Departmento de Fiscologia e Farmacologia, Coronel Nunes de Melo, Fortaleza-Ceará, Brasil.
Barbosa
Paulo S F
PS
Sousa
Ticiana M
TM
Martins
Alice M C
AM
Nobre
Arlandia C L
AC
Nascimento
Kyria S
KS
Teixeira
Edson H
EH
Pinto
Vicente P T
VP
Sampaio
Alexandre H
AH
Fonteles
Manassés C
MC
Cavada
Benildo S
BS
Monteiro
Helena S A
HS
D000818:Animals; D032449:Canavalia / Q000378:metabolism; D007668:Kidney / Q000187:drug effects*; D008297:Male; D037121:Plant Lectins / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012639:Seeds / Q000378:metabolism
D037121:Plant Lectins; C039268:lectin, Canavalia