title: The efficacy of sputum cytology in mass screening program for early detection of lung cancer.
abstract: BACKGROUND
  In order to evaluate the efficacy of sputum cytology in lung cancer screening, we re-analyzed the data obtained in our previous case-control study.
  
  
  METHODS
  The source population was defined as the previous screenees for reducing self-selection bias. Matching conditions were: gender, year of birth, municipality and smoking history.
  
  
  RESULTS
  Smoking adjusted odds ratio (SAOR) of dying from lung cancer for those screened by chest roentgenogram (CXp) only vs. not screened was 0.47, and that for those screened by sputum cytology (SpC) & CXp vs. not screened was 0.36, which was approximately three-fourths of the former. In another analysis, SAOR for those screened by SpC & CXp vs. those screened by CXp only was 0.63.
  
  
  CONCLUSIONS
  Although statistical significance was not obtained, there might be some possibility that the risk of lung cancer death in smokers would decrease by additional SpC, compared with CXp only.
authors.affiliation: Department of Thoracic Surgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan. sagawam@kanazawa-med.ac.jp
authors.forename: Motoyasu
authors.initials: M
authors.lastname: Sagawa
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Saito
authors.forename: Masami
authors.initials: M
authors.lastname: Sato
authors.forename: Satomi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Katsuo
authors.initials: K
authors.lastname: Usuda
authors.forename: Keiji
authors.initials: K
authors.lastname: Kanma
authors.forename: Chiaki
authors.initials: C
authors.lastname: Endo
authors.forename: Akira
authors.initials: A
authors.lastname: Sakurada
authors.forename: Makoto
authors.initials: M
authors.lastname: Sugita
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sakuma
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D011859:Radiography; D012907:Smoking / Q000009:adverse effects; D013183:Sputum / Q000166:cytology*