title: [Extracapsular spread in advanced laryngeal cancer].
abstract: The aim of the present study is to evaluate histopathological features of extracapsular spread detected in patients with laryngeal cancer.
  
  
  METHODS
  Specimens of 47 patients with laryngeal cancer were processed as Whole-Organ Serial Sections at the ENT Department of the Complutense University of Madrid between 1994/97.
  
  
  RESULTS
  Extracapsular metastases were found in 21 patients. The risk for extracapsular spread was higher in those patients with: supraglottic or piriform sinus cancer, more than 2-3 neck metastatic nodes, tumor diameter of more than 2 cm and N2 stage.
authors.affiliation: Departamento Cirugía II-ORL, Hospital Clínico San Carlos, Universidad Complutense de Madrid (UCM).
authors.forename: C
authors.initials: C
authors.lastname: Martín Villares
authors.forename: J
authors.initials: J
authors.lastname: Poch Broto
authors.forename: L
authors.initials: L
authors.lastname: Ortega Medina
authors.forename: M C
authors.initials: MC
authors.lastname: Iglesias Moreno
authors.forename: M J
authors.initials: MJ
authors.lastname: González Gimeno
authors.forename: F
authors.initials: F
authors.lastname: Cogolludo
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D015996:Survival Rate