title: [Tuberculosis and molecular biology].
abstract: Mycobacterium tuberculosis, the causative agent of tuberculosis (TB) hunting millions worldwide, is a challenge to work with in the laboratory. Modern molecular biology has provided extremely useful tools which have changed conventional diagnostic procedures in the TB laboratories. Research in molecular epidemiology is currently expanding our knowledge of the natural history of TB. Access to the genome sequence has opened new avenues for research in drug development and new vaccines. However, we are still awaiting the impact of these efforts in the resource-poor TB endemic countries.
authors.affiliation: Epidemiafdeling M5131, H:S Rigshospitalet, Blegdamsvej 9, DK-2100 København ø. bengaard@dadlnet.dk
authors.forename: Ase Bengård
authors.initials: AB
authors.lastname: Andersen
authors.forename: Troels
authors.initials: T
authors.lastname: Lillebaek
authors.forename: Christian
authors.initials: C
authors.lastname: Søborg
authors.forename: Isik Somuncu
authors.initials: IS
authors.lastname: Johansen
authors.forename: Vibeke Østergaard
authors.initials: VØ
authors.lastname: Thomsen
mesh_terms: D005821:Genetic Techniques; D006801:Humans; D025202:Molecular Diagnostic Techniques; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000276:immunology; D014376:Tuberculosis / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control; D032581:Tuberculosis Vaccines / Q000008:administration & dosage; D018088:Tuberculosis, Multidrug-Resistant / Q000235:genetics / Q000276:immunology / Q000517:prevention & control
chemical_list: D032581:Tuberculosis Vaccines