title: Methylphenidate in treatment of adults with Attention-Deficit/Hyperactivity Disorder.
abstract: Attention-Deficit/Hyperactivity Disorder (ADHD) can persist into adulthood with a continuation of the pattern of childhood psychopathology, cognition and functioning. Adult comorbidities include substance use disorders, antisocial personality disorder, anxiety, and depression. Studies have shown that as in children, methylphenidate treatment for adults can lead to a robust, dose-dependent improvement in ADHD symptoms. Future research is needed to evaluate the safety and efficacy of long-term treatment with methylphenidate (MPH).
authors.affiliation: Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA.
authors.forename: J
authors.initials: J
authors.lastname: Biederman
authors.forename: T
authors.initials: T
authors.lastname: Spencer
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000697:Central Nervous System Stimulants / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D015897:Comorbidity; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008134:Long-Term Care; D001523:Mental Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D008774:Methylphenidate / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate