title: A case series of ziprasidone overdoses.
abstract: In recent years, prescriptions for atypical antipsychotic medications have surpassed traditional antipsychotic agents because of improved treatment of the negative symptoms associated with schizophrenia and a relatively safer side effect profile. The relatively new atypical antipsychotic agent ziprasidone has become a popular treatment for schizophrenia, and like other psychiatric medications has potential for misuse. This series reports 3 cases of ziprasidone overdose. Diligence in cardiac monitoring and obtaining a history of possible co-ingestion are vital in the management of these patients.
authors.affiliation: Toxikon Consortium/Cook County Hospital, Section of Toxicology, Suite 500, 1900 West Polk Street, Chicago, IL 60612, USA.
authors.forename: Sean M
authors.initials: SM
authors.lastname: Bryant
authors.forename: Jeff
authors.initials: J
authors.lastname: Zilberstein
authors.forename: Kirk L
authors.initials: KL
authors.lastname: Cumpston
authors.forename: Dan D
authors.initials: DD
authors.lastname: Magdziarz
authors.forename: Dennis D
authors.initials: DD
authors.lastname: Costerisan
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000506:poisoning*; D003937:Diagnosis, Differential; D062787:Drug Overdose / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010879:Piperazines / Q000506:poisoning*; D013844:Thiazoles / Q000506:poisoning*
chemical_list: D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone