A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo.
Total of 7,495 children including 3,908 boys and 3,587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo alone (group 1), and 45 children with HLI were treated with 1% lindane shampoo and oral trimethoprim/sulfamethoxazole (group 2), and follow-up visits were conducted 2 and 4 weeks later. The children who still had HLI 2 weeks after the primary treatment were treated again. At the 2-week follow-up visit, the treatment success rates of groups 1 and 2 were 76.8% and 86.7%, respectively, and at the 4-week follow-up visit, the rates were 91.3% and 97.8%, respectively. No statistically significant synergistic effect was observed for the combination of a 1% lindane shampoo and oral trimethoprim/sulfamethoxazole.
Sim
Seobo
S
Department of Parasitology and Institute of Tropical Medicine, Yonsei University College ofMedicine, Seoul 120-752, Korea.
Lee
In-Yong
IY
Lee
Kyu-Jae
KJ
Seo
Jang-Hoon
JH
Im
Kyung-Il
KI
Shin
Myeong Heon
MH
Yong
Tai-Soon
TS
D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006203:Hair Preparations; D006306:Health Surveys; D001556:Hexachlorocyclohexane / Q000627:therapeutic use*; D006801:Humans; D007723:Korea / Q000453:epidemiology; D010373:Lice Infestations / Q000188:drug therapy* / Q000453:epidemiology*; D008297:Male; D010374:Pediculus; D015995:Prevalence; D013334:Students; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
D000890:Anti-Infective Agents; D006203:Hair Preparations; D001556:Hexachlorocyclohexane; D015662:Trimethoprim, Sulfamethoxazole Drug Combination