title: A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals.
abstract: The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2mm in planar and 2-3mm in tomographic imaging. Imaging studies in mice have been carried out both in 2D and 3D. Conventional radiopharmaceuticals have been used and the results have been compared with images from a clinically used system.
authors.affiliation: Department of Electrical and Computer Engineering, Institute of Communication and Computer Systems, National Technical University of Athens, Iroon Polytexneiou 9, Str. Zografos, Attiki, 15773, Athens, Greece. gloudos@central.ntua.gr
authors.forename: G K
authors.initials: GK
authors.lastname: Loudos
authors.forename: K S
authors.initials: KS
authors.lastname: Nikita
authors.forename: N D
authors.initials: ND
authors.lastname: Giokaris
authors.forename: E
authors.initials: E
authors.lastname: Styliaris
authors.forename: S C
authors.initials: SC
authors.lastname: Archimandritis
authors.forename: A D
authors.initials: AD
authors.lastname: Varvarigou
authors.forename: C N
authors.initials: CN
authors.lastname: Papanicolas
authors.forename: S
authors.initials: S
authors.lastname: Majewski
authors.forename: D
authors.initials: D
authors.lastname: Weisenberger
authors.forename: R
authors.initials: R
authors.lastname: Pani
authors.forename: F
authors.initials: F
authors.lastname: Scopinaro
authors.forename: N K
authors.initials: NK
authors.lastname: Uzunoglu
authors.forename: D
authors.initials: D
authors.lastname: Maintas
authors.forename: K
authors.initials: K
authors.lastname: Stefanis
mesh_terms: D000465:Algorithms; D000818:Animals; D001839:Bombesin / Q000493:pharmacokinetics*; D015902:Gamma Cameras; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D007668:Kidney / Q000000981:diagnostic imaging; D051379:Mice; D008819:Mice, Nude; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D013667:Technetium / Q000737:chemistry / Q000493:pharmacokinetics*
chemical_list: D019275:Radiopharmaceuticals; D013667:Technetium; D001839:Bombesin