Photoinactivation of bacterial strains involved in periodontal diseases sensitized by porphycene-polylysine conjugates.
Selected bacterial strains that are responsible for periodontal diseases are efficiently inactivated by visible light irradiation in the presence of porphycene-polylysine conjugates. Repeated photosensitization of surviving cells does not induce the selection of resistant bacterial strains and does not modify their sensitivity to antibiotic treatment.
Lauro
Federico M
FM
Department of Histology, Microbiology and Medical Biotechnology, University of Padova, Via A. Gabelli 63, 35121 Padova, Italy.
Pretto
Patrizia
P
Covolo
Loredana
L
Jori
Giulio
G
Bertoloni
Giulio
G
D001419:Bacteria / Q000187:drug effects* / Q000472:pathogenicity / Q000528:radiation effects; D006801:Humans; D008027:Light; D010510:Periodontal Diseases / Q000382:microbiology*; D017319:Photosensitizing Agents / Q000494:pharmacology*
D017319:Photosensitizing Agents