title: Two new non-steroidal constituents from Dioscorea futschauensis R. Kunth.
abstract: Dioscorone A (1) and a new isocoumarin derivative (2) were isolated from the rhizome of Dioscorea futschauensis R. Kunth. The structures of 1 and 2 were elucidated on the basis of detailed analysis of NMR spectra. Their anti-fungal activity against Pyricularia oryzae and cytotoxic activity on K562 and HCT-15 cell lines were evaluated in vitro.
authors.affiliation: Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang, China.
authors.forename: W H
authors.initials: WH
authors.lastname: Liu
authors.forename: L S
authors.initials: LS
authors.lastname: Wang
authors.forename: B
authors.initials: B
authors.lastname: Cai
authors.forename: S X
authors.initials: SX
authors.lastname: Yao
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000187:drug effects; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D027742:Dioscorea / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D018517:Plant Roots / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014407:Tumor Cells, Cultured
chemical_list: D000935:Antifungal Agents; D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins; C473339:dioscorone A