[Hepatic amyloidosis as cause of severe intrahepatic cholestasis].
The liver is frequently involved by amyloidosis, but hyperbilirubinemia and liver failure are uncommon features. A mild elevation of the serum alkaline phosphatase value and, less frequently, hepatomegaly are the most common findings. Usually the patients have no symptoms related with the liver involvement; the clinical manifestation and the long term prognosis depends on the renal and cardiac disease. We report an unusual clinical presentation of primary amyloidosis in a previously asymptomatic 65 years old woman who was admitted to the hospital because of ictericia and ascitis mimicking a drug induced acute hepatic failure.
Gavilán
J C
JC
Servicio de Medicina Interna, Hospital Universitario Virgen de la Victoria, Campus de Teatinos, 29017 Málaga.
Bermúdez
F J
FJ
Márquez
A
A
Sánchez-Carrillo
J J
JJ
González-Santos
P
P
D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D002780:Cholestasis, Intrahepatic / Q000209:etiology*; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D017114:Liver Failure, Acute / Q000209:etiology*; D012720:Severity of Illness Index