[Tubulo-interstitial nephritis and uveitis (TINU syndrome): a new pediatric case].
TINU is a rare disease of unknown etiology that associates acute tubulointerstitial nephritis and uveitis in a context of systemic symptoms (asthenia, weight loss, fever) and inflammatory biological signs. We report a new case in a 10-year-old girl with unilateral uveopapillitis and renal insufficiency caused by interstitial nephritis (creatininemia: 225 micro mol/l). Complete recovery was obtained with high-dose systemic corticotherapy, with the patient remaining free of disease 2.5 years after the end of treatment. The disappearance of renal lesions was histologically verified.
Bensmail
D
D
Service de Médecine Interne, Centre Hospitalier National d'Ophthalmologie des Quinze-Vingts, Paris.
Rossignol
I
I
Tuil
E
E
Sabourin
C
C
Morin
Y
Y
Héron
E
E
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D009395:Nephritis, Interstitial / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use*; D012074:Remission Induction; D013577:Syndrome; D014605:Uveitis / Q000188:drug therapy*
D000893:Anti-Inflammatory Agents; D011241:Prednisone