[Normotensive scleroderma renal crisis].
A 60 year old male patient having systemic scleroderma and normotensive scleroderma renal crisis was admitted in our hospital. He presented polyarticular, esophagic, lung and skin compromise. Before admission he had been treated with high doses of corticosteroids. We believe corticosteroids led to the worsening of renal damage with renal failure, microangiopathic hemolytic anemia without high blood pressure. The 10% of these cases have normal blood pressure. The patient was treated with enalapril and hemodialysis. There was no favourable response to this treatment and he died seven days after admission.
Villaverde
Marcelo
M
Servicio de Clínica Médica, Hospital Nacional Alejandro Posadas, Mosconi 585, 1706 Haedo, Provincia Buenos Aires, Argentina.
González
Alejandra
A
Orellano
Pablo
P
Lafage
Matías
M
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000743:Anemia, Hemolytic / Q000139:chemically induced; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001794:Blood Pressure; D004656:Enalapril / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012595:Scleroderma, Systemic / Q000150:complications* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000806:Angiotensin-Converting Enzyme Inhibitors; D004656:Enalapril