Periodontal microbiota and clinical periodontal status in a rural sample in southern Thailand.
We sought to determine (i) the association of subgingival bacterial profiles to clinical periodontal status in a population with limited access to dental care in Thailand, and (ii) the external validity of our earlier findings from a similar study in rural China. We examined 356 subjects, 30-39 yr old and 50-59 yr old, with respect to clinical periodontal status and subgingival plaque at maximally 14 sites per subject. Checkerboard hybridizations were used to analyse a total of 4343 samples. The prevalence of the 27 species investigated ranged between 87.2% and 100%. Discriminant analysis based on microbial profiles classified correctly 67.5% of all deep (> or = 5 mm) and 64.2% of all shallow sites, and 67.4% of all subjects with and 69.3% of all subjects without > or = 3 deep pockets. High colonization by 'red complex' bacteria was four times as likely (95% Confidence Limits (CL) 2.5-6.6) in subjects with > or = 10 sites with attachment loss of > or = 5 mm, and 4.3 times as likely (95% CL 2.6-7.1) in subjects with > or = 30 such sites. The data confirmed (i) the ubiquitous prevalence of the bacteria investigated in subjects with no regular access to dental care; and (ii) the high odds for periodontal pathology conferred by increased levels of specific periodontal bacteria.
Papapanou
P N
PN
Columbia University School of Dental and Oral Surgery, NY, USA.
Teanpaisan
R
R
Obiechina
N S
NS
Pithpornchaiyakul
W
W
Pongpaisal
S
S
Pisuithanakan
S
S
Baelum
V
V
Fejerskov
O
O
Dahlén
G
G
D000190:Actinomyces / Q000145:classification; D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000145:classification; D001439:Bacteroides / Q000145:classification; D002681:China; D016001:Confidence Intervals; D003773:Dental Plaque / Q000382:microbiology*; D016002:Discriminant Analysis; D005260:Female; D016967:Fusobacterium nucleatum / Q000145:classification; D006090:Gram-Negative Bacteria / Q000145:classification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D017622:Periodontal Attachment Loss / Q000382:microbiology; D010510:Periodontal Diseases / Q000382:microbiology*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology; D010519:Periodontium / Q000382:microbiology*; D017861:Porphyromonas / Q000145:classification; D018720:Prevotella / Q000145:classification; D015203:Reproducibility of Results; D012423:Rural Health; D013291:Streptococcus / Q000145:classification; D013785:Thailand; D014208:Treponema / Q000145:classification