[Clinical analysis of 80 perinatal death from hepatic diseases in pregnancy].
OBJECTIVE
To explore the factors associated with perinatal death of hepatic diseases in pregnancy (HDIP) and make feasible suggestions and measures for perinatal care of high risk patients.


METHODS
The 80 perinatal death cases of hepatic diseases in pregnancy (HDIP) during 1991-2000 in our hospital were analyzed retrospectively.


RESULTS
The perinatal mortality of HDIP in our hospital during the last 10 years was 17.99 approximately 65% was in utero death. Perinatal mortality was different between male (21.64%) and female (10.11%) (P<0.01). Compared first 5 years with last 5 years author found that the perinatal mortality of HDIP had no significant decrease (P>0.05). The perinatal mortality in city and suburbs had decreased, while in the floating population from other provinces the perinatal mortality had increased. The perinatal death was mainly caused by pregnancy induced hypertension (PIH) and asphyxia. But for the HBV carrier mothers the causes of death included umbilical cord problems, premature rupture of membrane and asphyxia.


CONCLUSIONS
The perinatal death mortality was increased by HDIP, deaths were essentially associated with pregnancy induced hypertension and asphyxia and the floating population and male gender were high risks. To enhance the management of HDIP or immigration, take effective therapies of hepatitis and improvement of resuscitation of newborns are critically important.
Liu
Ying
Y
Beijing You An Hospital, Beijing 100054, China.
Chang
Lingzhi
L
Zhong
Chongfang
C
Huang
Chun
C
D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D005260:Female; D005313:Fetal Death / Q000453:epidemiology*; D005316:Fetal Distress / Q000209:etiology / Q000401:mortality; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008107:Liver Diseases / Q000150:complications / Q000401:mortality*; D008297:Male; D011225:Pre-Eclampsia / Q000150:complications / Q000401:mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality*; D012189:Retrospective Studies; D012737:Sex Factors