[Prognostic factors of 60 nasal cavity carcinoma patients].
OBJECTIVE
To evaluate the treatment modalities and the prognostic factors of nasal cavity carcinoma.


METHODS
A retrospective study was done on 60 nasal cavity carcinoma patients treated from 1985 to 1992. Thirty-four patients received radiotherapy alone and 26 patients received surgery plus radiotherapy. Kaplan-Meier method was used to evaluate the survival, Log-rank test to assess the difference between these two groups and Cox proportional hazard model by multivariate analysis.


RESULTS
The overall 5- and 10-year survival rates were 55.9% and 36.9% respectively. The 5- and 10-year survival rates were 79.0% and 57.9% in patients with early lesions (stage I, II) and 44.1% and 26.0% in patients with advanced lesions (stage III, IV) (P = 0.005). There was no significant difference in the survival rate between radiotherapy alone and radiotherapy plus surgery (P = 0.33). Patients with squamous cell carcinoma had obviously poorer survival rate than patients with adenocarcinoma (P = 0.04). Patients with positive nodes had a lower survival rate compared with negative node patients (P = 0.09).


CONCLUSIONS
Histological type and clinical stage, but not method of treatment or neck node metastasis, are the important prognostic factors.
Hu
Weihan
W
Department of Radiation Oncology, Cancer Center, Guangzhou 510060, China.
Xie
Fangyun
F
Chen
Dezhu
D
Chen
Ming
M
He
Dandan
D
Mao
Zhida
Z
Pan
Guoying
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009296:Nasal Cavity; D009333:Neck; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate