title: The effect of image size on nuchal translucency measurement.
abstract: OBJECTIVE
  To assess the effect of altering image size on the absolute nuchal translucency (NT) measurement.
  
  
  METHODS
  NT was measured at three image magnifications (60%, 100% and 200%) in 120 singleton pregnancies.
  
  
  RESULTS
  The mean +/- SD NT measurements were 1.52 +/- 0.57 mm, 1.35 +/- 0.53 mm and 1.18 +/- 0.48 mm at 60%, 100% and 200% magnification, respectively (p = 0.00001).
  
  
  CONCLUSIONS
  The measurement of NT decreases significantly with increasing image size. Optimisation of NT as a method of screening will require agreed standardisation of image magnification.
authors.affiliation: Fetal Diagnostic Unit, Monash Medical Centre, Monash University, Clayton, Victoria, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Edwards
authors.forename: Sheila
authors.initials: S
authors.lastname: Mulvey
authors.forename: Euan M
authors.initials: EM
authors.lastname: Wallace
mesh_terms: D000293:Adolescent; D000328:Adult; D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008423:Maternal Age; D009333:Neck / Q000000981:diagnostic imaging* / Q000196:embryology; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018566:Pregnancy, High-Risk; D011446:Prospective Studies; D012016:Reference Values; D015203:Reproducibility of Results; D016216:Ultrasonography, Prenatal / Q000379:methods* / Q000592:standards