title: Biosynthesis of the sesquiterpene hodgsonox from the New Zealand liverwort Lepidolaena hodgsoniae.
abstract: The incorporation of [1-13C] labelled glucose into hodgsonox, a sesquiterpene epoxide with a unique, doubly allylic ether functionality has been studied in axenic cultures of the liverwort Lepidolaena hodgsoniae. Quantitative 13C NMR spectroscopic analysis showed that the isoprene units are derived exclusively from the methylerythritol phosphate pathway.
authors.affiliation: Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.
authors.forename: Anna J
authors.initials: AJ
authors.lastname: Barlow
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Lorimer
authors.forename: Ed R
authors.initials: ER
authors.lastname: Morgan
authors.forename: Rex T
authors.initials: RT
authors.lastname: Weavers
mesh_terms: D002247:Carbon Isotopes; D046508:Culture Techniques / Q000379:methods; D005947:Glucose / Q000737:chemistry / Q000378:metabolism; D035926:Hepatophyta / Q000254:growth & development / Q000378:metabolism*; D009520:New Zealand; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D012717:Sesquiterpenes / Q000737:chemistry / Q000378:metabolism*; D013403:Sugar Phosphates / Q000737:chemistry / Q000378:metabolism
chemical_list: D002247:Carbon Isotopes; D012717:Sesquiterpenes; D013403:Sugar Phosphates; D005947:Glucose