title: Melanoma metastatic to central neurocytoma: a novel case of tumor-to-tumor metastasis.
abstract: We report a case of a 43-year-old man with known metastatic melanoma and two intracranial tumors, one of which was resected and confirmed to be melanoma. At autopsy, the second lesion was found to be a central neurocytoma harboring metastatic melanoma. To our knowledge, this represents the first reported case of tumor-to-tumor metastasis to a central neurocytoma. The most common pattern of tumor-to-tumor metastasis for intracranial neoplasms, in which an aggressive high-grade malignancy serves as the source tumor and a more indolent neoplasm serves as the recipient tumor, is affirmed by the present novel example.
authors.affiliation: Department of Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: Heather M
authors.initials: HM
authors.lastname: Brown
authors.forename: Ian E
authors.initials: IE
authors.lastname: McCutcheon
authors.forename: Norman E
authors.initials: NE
authors.lastname: Leeds
authors.forename: Donald S
authors.initials: DS
authors.lastname: Schomer
authors.forename: Mario A
authors.initials: MA
authors.lastname: Luna
authors.forename: Gregory N
authors.initials: GN
authors.lastname: Fuller
mesh_terms: D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000556:secondary*; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis; D018306:Neurocytoma / Q000175:diagnosis*; D012688:Septum Pellucidum / Q000473:pathology