The effect of composition upon the physical and chemical properties of biodegradable gelatin polymer matrixes.
The aim of the research was to obtain porous, elastic gel matrix with a long decomposition time as a carrier of therapeutic substance. The pigskin gelatin of various degrees of gelation and glycerol was used in the experiment. The studies showed that such biopolymer as gelatin is enable to prepare the matrix which can remain in organism for a long time and a porous structure of the sponge allows to increase absorbing capacity of exudate.
Pluta
Janusz
J
Department of Applied Pharmacy, Wrocław Medical Uniwersity.
Haznar
Dorota
D
D000042:Absorption; D000818:Animals; D001458:Bandages; D001673:Biodegradation, Environmental; D004337:Drug Carriers; D005781:Gelatin Sponge, Absorbable / Q000737:chemistry*; D008422:Materials Testing; D010447:Peptide Hydrolases / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D013552:Swine
D004337:Drug Carriers; D011108:Polymers; D010447:Peptide Hydrolases