title: Synthesis of novel C2-symmetrical chiral sulfides and their utility in asymmetric epoxidation of aldehydes.
abstract: Novel C(2)-symmetrical chiral sulfides were synthesized from (R,R)-tartaric acid and their utility in the asymmetric epoxidation of aldehydes with benzyl bromide was examined. Among the sulfides used, silyl ether-type sulfides were found to be superior to diol- and benzyl ether-type sulfides. Also, the presence of an aromatic group on the sulfide was proven to be an important factor for increasing enantioselectivity.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Shinjuku-ku, Tokyo, Japan. ishizaki@ps.kagu.tus.ac.jp
authors.forename: Miyuki
authors.initials: M
authors.lastname: Ishizaki
authors.forename: Osamu
authors.initials: O
authors.lastname: Hoshino