[Efficacy of ursodeoxycholic acid in gallbladder cholesterosis accompanied by cholecystolithiasis].
23 patients with gall-bladder cholesterosis associated with cholesterol gallstones were treated with ursodeoxycholic acid preparations. A regression of cholesterol polyps was recorded in 56.5% against the background of treatment, and complete or partial dissolution of gallstones was observed in 87%. The efficiency of dissolution of cholesterol polyps and stones in the gall-bladder went up along with the extension of the therapy terms, reaching its maximum by 7-9 months of treatment. The dissolution rates were higher for gallstones than for cholesterol polyps. The volume of bile being secreted increased, and the gall-bladder contractile function improved in the course of treatment.
Il'chenko
A A
AA
Central Scientific Research Institute of Gastroenterology, Moscow.
Orlova
Iu N
IuN
D000293:Adolescent; D000328:Adult; D000368:Aged; D002769:Cholelithiasis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use*
D014580:Ursodeoxycholic Acid; D002784:Cholesterol