On long-term depression induced by activation of G-protein coupled receptors.
In this mini-review I consider the mechanisms by which activation of glutamate and acetylcholine metabotropic receptors can result in the induction of long-term depression. Two regions of the CNS will receive particular attention; the CA1 region of hippocampus and the perirhinal cortex.
Bashir
Zafar I
ZI
MRC Centre for Synaptic Plasticity, Department of Anatomy, University of Bristol, Bristol BS8 1TD, UK. z.i.bashir@bris.ac.uk
D000818:Animals; D001921:Brain / Q000502:physiology; D036881:Long-Term Synaptic Depression / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D011950:Receptors, Cholinergic / Q000378:metabolism*; D018094:Receptors, Metabotropic Glutamate / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
D011950:Receptors, Cholinergic; D018094:Receptors, Metabotropic Glutamate