[Multi-variate regression analysis of clinicopathological characteristics and prognosis of colorectal cancer].
OBJECTIVE
To evaluate the relationship between clinicopathologic features and prognosis of colorectal cancer after surgical treatment.


METHODS
The clinical characteristics, pathologic features and survival rate of 761 patients with colorectal cancer after surgical treatment were univariately and multivariately analyzed.


RESULTS
The overall 3- and 5-year survival rates of patients with colorectal cancer after surgical treatment were 62.9% and 60.7% with a median survival of 1,825 days. The factors of gross findings, degree of differentiation, infiltration, nodal and distant metastasis and neoplastic intestinal obstruction influenced the survival rate by univariate analysis. The factors of Dukes stage, gross tumor configuration, intramural spread and differentiation degree were available independent prognostic factors through multivariate analysis.


CONCLUSIONS
Dukes stage, as the most important available independent prognostic factor (P < 0.0005), is able to assess the postoperative survival.
Wang
Jian-ping
JP
Department of Gastrointestinopancreatic Surgery, First Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China.
Yang
Zu-li
ZL
Wang
Lei
L
Dong
Wen-guang
WG
Huang
Yi-hua
YH
Qin
Jian-zhang
JZ
Zhan
Wen-hua
WH
D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D012044:Regression Analysis; D015996:Survival Rate