[Persistence of immunity after hepatitis B vaccination].
The paper recalls different preparations of vaccines (including these containing S, preS1 and preS2 antigens), schemes of vaccinations and their effects. The possible causes of hyporeactivity to hepatitis B vaccines, both technical and dependent on deficiency of immunity, or immunogenetic profile of a vaccine were discussed. The persistence of anti-HBs responses after natural infection and post-vaccination was compared. Finally, a possibility of persistence of post-vaccination cellular immunity for at least 15 years was discussed.
Madaliński
Kazimierz
K
Zakład Immunopatologii Państwowego Zakładu Higieny w Warszawie. kmadalinski@pzh.gov.pl
D006509:Hepatitis B / Q000276:immunology* / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D017325:Hepatitis B Vaccines / Q000276:immunology* / Q000627:therapeutic use; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D011498:Protein Precursors / Q000097:blood; D013997:Time Factors
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D011498:Protein Precursors; C050806:presurface protein 1, hepatitis B surface antigen; C050807:presurface protein 2, hepatitis B surface antigen