title: Tumor detection in the bladder wall with a measurement of abnormal thickness in CT scans.
abstract: Virtual cystoscopy is a developing technique for bladder cancer screening. In a conventional cystoscopy, an optical probe is inserted into the bladder and an expert reviews the appearance of the bladder wall. Physical limitations of the probe place restrictions on the examination of the bladder wall. In virtual cystoscopy, a computed tomography (CT) scan of the bladder is acquired and an expert reviews the appearance of the bladder wall as shown by the CT. The task of identifying tumors in the bladder wall has often been done without extensive computational aid to the expert. We have developed an image processing algorithm that aids the expert in the detection of bladder tumors. Compared with an expert observer reading the CT, our algorithm achieves 89% sensitivity, 88% specificity, 48% positive predictive value, and 98% negative predictive value.
authors.affiliation: Telecommunications Laboratory, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium. jaume@tele.ucl.ac.be
authors.forename: Sylvain
authors.initials: S
authors.lastname: Jaume
authors.forename: Matthieu
authors.initials: M
authors.lastname: Ferrant
authors.forename: Benoît
authors.initials: B
authors.lastname: Macq
authors.forename: Lennox
authors.initials: L
authors.lastname: Hoyte
authors.forename: Julia R
authors.initials: JR
authors.lastname: Fielding
authors.forename: Andreas
authors.initials: A
authors.lastname: Schreyer
authors.forename: Ron
authors.initials: R
authors.lastname: Kikinis
authors.forename: Simon K
authors.initials: SK
authors.lastname: Warfield
mesh_terms: D019412:Anatomy, Cross-Sectional / Q000379:methods; D004452:Echocardiography / Q000379:methods; D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging*