[Uveal lymphoid infiltration with systemic extension].
METHODS
We report the case of a patient who was surgically treated in his right eye because of an uncontrollable glaucoma and a retinal detachment without retinal break. Ultrasound and computed tomography showed diffuse choroidal thickening. During 6 years of follow-up, he developed a major ocular and orbitary invasion and bone marrow infiltration. He was treated by enucleation and chemotherapy with apparent total remission.


CONCLUSIONS
Reactive lymphoid hyperplasia of the uvea consists of a lymphocytic proliferation that primarily involves the uveal tract. This process is regarded as a low malignant condition, but this case of late diagnosis showed a tendency to orbital and systemic extension.
Barbón García
J J
JJ
Servicio de Oftalmología, Hospital San Agustín, Avilés, Asturias. jjbarbon@telecable.es
Viña Escalar
C
C
Menéndez Fernández
C L
CL
Fernández Alvarez
C
C
Carballo Fernández
C
C
Villarreal Renedo
P M
PM
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D015862:Choroid Diseases / Q000473:pathology* / Q000601:surgery; D002830:Choroid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D003520:Cyclophosphamide / Q000008:administration & dosage; D018450:Disease Progression; D004317:Doxorubicin / Q000008:administration & dosage; D015353:Eye Enucleation; D015355:Glaucoma, Neovascular / Q000209:etiology; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D016393:Lymphoma, B-Cell / Q000097:blood / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000556:secondary; D010266:Paraproteins; D011241:Prednisone / Q000008:administration & dosage; D019310:Pseudolymphoma / Q000473:pathology* / Q000601:surgery; D012074:Remission Induction; D012163:Retinal Detachment / Q000209:etiology* / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
D007145:Immunoglobulin kappa-Chains; D010266:Paraproteins; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone