title: [Comparison of cerebral blood flow with Xe-inhalation CT and perfusion CT].
abstract: Cerebral blood flow (ml/min/100g) (CBF) was detected by two methods, static xenon inhalation dynamic CT (Xe-CT) and perfusion CT, and a comparison of these two methods (Xe-CBF and perfusion CBF) was carried out in the same cases. Xe CT used 30% static xenon, 4 min wash-in, and 5 min wash-out, while perfusion CT was done by injecting 30 ml of non-ionic contrast medium at a rate of 9 ml/sec. Forty-eight patients underwent these examinations (30 serious cases and 18 mild). The correlation coefficients in the hemispheric area were r=0.713 (p<0.01) with Xe-CBF and perfusion CBF in mild cases and r=0.567 (p<0.01) in serious cases. The two CBF values were especially disparate in serious cases. The value for perfusion CBF was almost double that of Xe-CBF in these cases. Perfusion CT was a useful examination for the detection of CBF, but in serious cases, CBF needs to be determined by Xe-CT as well.
authors.affiliation: Department of Radiology, Toho University Oomori Hospital.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Machida
authors.forename: Hideharu
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D020144:Basal Ganglia Cerebrovascular Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014978:Xenon / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D014978:Xenon