Guided osteogenesis using synthetic membranes and alloplastic materials: a pilot study.
OBJECTIVE
The aim of this study was to develop an experimental model for the assessment of bone augmentation, and in doing so, compare the use of beta-tricalcium phosphate (TCP) bone grafts in combination with Gore-Tex augmentation material (GTAM) and GTAM without TCP.


METHODS
Calvarial sites in eight Sprague Dawley rats were prepared for bone augmentation. Graft materials and Hermann stainless steel bone pins were used for localized bone augmentation. Specimens were subjected to macroscopic and histological evaluation at the sixth week.


RESULTS
Bone formation was significantly higher in the group with the graft support.


CONCLUSIONS
TCP bone grafts used in conjunction with supporting pins may contribute to successful bone regeneration by osseoconduction and by maintaining the membrane-created space. At the sixth week, guided bone regeneration utilizing Gore-Tex augmentation material and TCP bone grafts resulted in the formation of viable new bone.
Aybar
Buket
B
Faculty of Dentistry, Department of Oral Surgery, Istanbul University, Istanbul, Turkey. buketaybar@hotmail.com
Günhan
Omer
O
Bilgiç
Levent
L
Emes
Yusuf
Y
D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation; D002130:Calcium Phosphates; D048091:Guided Tissue Regeneration / Q000379:methods*; D008297:Male; D008567:Membranes, Artificial; D010865:Pilot Projects; D011138:Polytetrafluoroethylene; D051381:Rats; D017207:Rats, Sprague-Dawley; D012886:Skull; D018709:Statistics, Nonparametric
D018786:Bone Substitutes; D002130:Calcium Phosphates; D008567:Membranes, Artificial; C485817:beta-tricalcium phosphate; D011138:Polytetrafluoroethylene; C018392:tricalcium phosphate