title: 166Ho-coated balloon for vascular brachytherapy.
abstract: A simple procedure was developed for coating the surface of a conventional percutaneous transluminal coronary angioplasty balloon angioplasty catheter with 166Ho. The absorbed dose delivered by the surface-coated catheter is twice that of a similar catheter filled with a solution containing the same activity of 166Ho. Leakage tests show that <0.6% of the coated activity is removable from the surface of the catheter. The coated catheter removes the risk of release of the 166Ho into the body as a result of rupture of the balloon, and also reduces the radiation exposure to staff.
authors.affiliation: RI and Radiation Application Team, Korea Atomic Energy Research Institute, 150, Dukjin-dong Yuseong-gu, 305-353, Daejon, South Korea.
authors.forename: Young-Don
authors.initials: YD
authors.lastname: Hong
authors.forename: Sun-Ju
authors.initials: SJ
authors.lastname: Choi
authors.forename: Kyung-Hwa
authors.initials: KH
authors.lastname: Kim
authors.forename: Byung-Chul
authors.initials: BC
authors.lastname: Shin
authors.forename: Woong-Woo
authors.initials: WW
authors.lastname: Park
authors.forename: Sang-Hyun
authors.initials: SH
authors.lastname: Park
authors.forename: Kyung Bae
authors.initials: KB
authors.lastname: Park
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D001918:Brachytherapy / Q000379:methods*; D003327:Coronary Disease / Q000532:radiotherapy; D006695:Holmium / Q000008:administration & dosage* / Q000737:chemistry*; D006801:Humans; D011834:Radiation Monitoring; D011835:Radiation Protection; D011868:Radioisotopes / Q000008:administration & dosage* / Q000737:chemistry* / Q000493:pharmacokinetics; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics; D011879:Radiotherapy Dosage; D013997:Time Factors
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals; D006695:Holmium