Phenylpropanoid glycosides from Rhodiola rosea.
Rhodiola rosea L. (Golden Root) has been used for a long time as an adaptogen in Chinese traditional medicine and is reported to have many pharmacological properties. Along its known secondary metabolites tyrosol (1), salidroside (rhodioloside) (2), rosin (3), rosarin (4), rosavin (5), sachaliside 1 (6) and 4-methoxy-cinnamyl-O-beta-D-glucopyranoside (7), four compounds were isolated from aqueous methanol extract of the plant and identified as cinnamyl-(6'-O-beta-xylopyranosyl)-O-beta-glucopyranoside (8), 4-methoxy-cinnamyl-(6'-O-alpha-arabinopyranosyl)-O-beta-glucopyranoside (9), picein (10) and benzyl-O-beta-glucopyranoside (11) by UV, MS and NMR methods. Compounds 8 and 9 are new natural compounds whereas compounds 10 and 11 were isolated first time from R. rosea. Also the compounds 6 and 7 are isolated earlier only from the callus cultures of the plant but not from the differentiated plant.
Tolonen
Ari
A
Department of Chemistry, University of Oulu, Finland. ari.tolonen@oulu.fi
Pakonen
Minna
M
Hohtola
Anja
A
Jalonen
Jorma
J
D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D010666:Phenylpropionates / Q000737:chemistry* / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots; D029771:Rhodiola
D006027:Glycosides; D010666:Phenylpropionates; D010936:Plant Extracts