title: Comparative biology of gamma delta T cells.
abstract: Accumulative evidence suggests that resident gamma delta T cells in epithelia are biologically distinct from systemic gamma delta T cells in the circulation. Murine resident gamma delta T cells have innate immune characteristics and play an important role in tissue homeostasis after damages. In contrast, a unique subset of circulating gamma delta T cells in primates, like alpha beta T cells, can mount adaptive immune responses in infections. This article compares biological features between resident and circulating gamma delta T cells.
authors.affiliation: zchen@caregroup.harvard.edu
authors.forename: Zheng W
authors.initials: ZW
authors.lastname: Chen
mesh_terms: D000818:Animals; D004848:Epithelium / Q000276:immunology; D006801:Humans; D007156:Immunologic Memory; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta