Retroperitoneal schwannoma with features of gastrointestinal schwannoma. A case report.
A case of retroperitoneal schwannoma with histological features of gastrointestinal (GI) schwannoma occurring in a 67-year-old woman is reported. The tumor was composed of spindle cells with focal pseudoatypism and it showed several features typical of gastrointestinal-type schwannoma such as lymphocytic infiltration, peripheral cuff of lymphocytes, lack of Antoni A pattern, and absence of thick walled vessels. Immunohistochemically, the tumor showed diffuse reactivity for S100 protein and glial fibrillary acidic protein. The authors discuss a phenotypical similarity of the lesion with GI schwannoma as well as the possible existence of GI-type schwannoma outside the tubal GI tract.
Zámecník
M
M
Sikl's Department of Pathology, Faculty Hospital, Charles University, Pilsen, Czech Republic. zamecnik@medima.cz
Koys
F
F
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D009442:Neurilemmoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D012186:Retroperitoneal Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*