title: Immunoregulatory Properties of alpha(2)-Macroglobulin.
abstract: Native and modified with ammonium ions alpha(2)-macroglobulin forms exhibit similar abilities to influence proliferative activity and secretion of immunoglobulins in cultures of human blood mononuclear cells in vitro. Effects of modified with ammonium ions alpha(2)-macroglobulin were more significant than those of native alpha(2)-macroglobulin. Revealed properties of native alpha(2)-macroglobulin could be conditioned by a partial modification of its structure with endogenous proteinases or cytokines, some of which were shown to be common affinants for both forms.
authors.affiliation: Central Research Laboratory, Physician Postgraduate Training Institute, Novokuznetsk, Russia.
authors.forename: N. V.
authors.initials: NV
authors.lastname: Maltseva
authors.forename: O. F.
authors.initials: OF
authors.lastname: Lykova
authors.forename: T. V.
authors.initials: TV
authors.lastname: Konysheva
authors.forename: R. M.
authors.initials: RM
authors.lastname: Zorina
authors.forename: S. V.
authors.initials: SV
authors.lastname: Arhipova
authors.forename: T. S.
authors.initials: TS
authors.lastname: Chirikova
authors.forename: N. A.
authors.initials: NA
authors.lastname: Zorin