title: Understanding and preventing the edge effect.
abstract: Edge stenosis, combining neointimal proliferation and negative remodeling, remains a serious limitation of vascular brachytherapy. This review comprehensively presents terminology, definitions, mechanisms, and treatment strategies to better understand the complexities of edge narrowing. The major contributors to this phenomenon are known; understanding the practical solutions will enable us to further minimize the problem of the edge effect.
authors.affiliation: Cardiovascular Research Institute, Division of Cardiology, Washington Hospital Center, 110 Irving Street, NW, Suite 4B-1, Washington, DC 20010, USA.
authors.forename: Edouard
authors.initials: E
authors.lastname: Cheneau
authors.forename: Roswitha
authors.initials: R
authors.lastname: Wolfram
authors.forename: Laurent
authors.initials: L
authors.lastname: Leborgne
authors.forename: Ron
authors.initials: R
authors.lastname: Waksman
mesh_terms: D001918:Brachytherapy; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000517:prevention & control* / Q000532:radiotherapy*; D006801:Humans; D011340:Problem Solving; D011879:Radiotherapy Dosage