title: Prospective study of coinfection in patients with erythema migrans.
abstract: The frequency of coinfection with Borrelia burgdorferi and either Anaplasma phagocytophila or Babesia microti among patients with erythema migrans, the initial skin lesion of Lyme disease, was assessed in 2 mainland locations in Rhode Island and Connecticut in a 4-year prospective study. Of the 93 patients with culture-proven erythema migrans, 2 (2%) patients had coinfection with A. phagocytophila and 2 (2%) had coinfection with B. microti. We concluded that the frequency of coinfection with these agents was low among patients with erythema migrans in the study areas.
authors.affiliation: Division of Rheumatology and Immunology, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA. asteere@partners.org
authors.forename: Allen C
authors.initials: AC
authors.lastname: Steere
authors.forename: Gail
authors.initials: G
authors.lastname: McHugh
authors.forename: Carolin
authors.initials: C
authors.lastname: Suarez
authors.forename: Jason
authors.initials: J
authors.lastname: Hoitt
authors.forename: Nitin
authors.initials: N
authors.lastname: Damle
authors.forename: Vijay K
authors.initials: VK
authors.lastname: Sikand
mesh_terms: D000328:Adult; D000709:Anaplasma / Q000302:isolation & purification*; D000712:Anaplasmosis / Q000453:epidemiology; D000818:Animals; D025065:Borrelia burgdorferi / Q000302:isolation & purification*; D003237:Connecticut / Q000453:epidemiology; D015787:Erythema Chronicum Migrans / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012237:Rhode Island / Q000453:epidemiology