Isolation from blood culture of a Leclercia adecarboxylata strain producing an SHV-12 extended-spectrum beta-lactamase.
We report on the first isolation of an extended-spectrum beta-lactamase-producing Leclercia adecarboxylata strain from the bloodstream in a 58-year-old man with acute myeloid leukemia. The strain, resistant to ceftazidime, cefotaxime, and aztreonam, produces the SHV-12 beta-lactamase, one of the most common variants found in Italian nosocomial isolates of Enterobacteriaceae.
Mazzariol
Annarita
A
Department of Pathology, Microbiology Section, University of Verona, Verona, Italy.
Zuliani
Jessica
J
Fontana
Roberta
R
Cornaglia
Giuseppe
G
D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001398:Aztreonam / Q000494:pharmacology; D016470:Bacteremia / Q000382:microbiology; D001769:Blood / Q000382:microbiology*; D002442:Ceftazidime / Q000494:pharmacology; D003470:Culture Media; D004755:Enterobacteriaceae / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000382:microbiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D003470:Culture Media; D002442:Ceftazidime; C107198:beta-lactamase SHV-12; D001618:beta-Lactamases; D001398:Aztreonam