[Management of the bank of biological material in the hospital-based SEROCO and HEMOCO cohorts of HIV-infected patients].
The French SEROCO and HEMOCO hospital-based cohorts have enrolled and followed HIV-infected patients, before and after the highly active antiretroviral therapy era. Among the objectives in 1988, was explicitly mentioned the constitution of a centralised bank of biological material (serums at enrollment and every 6 months, PBMC at enrollment and every 18 months). This paper details the organisation of the bank and the numerous studies performed from this bank, and presents a few simple decision rules which have been developed with the growing acquired experience.
Meyer
L
L
Service d'Epidémiologie, INSERM U569, Hôpital de Bicêtre AP/HP, 82, rue du Général-Leclerc, 94276 Le Kremlin-Bicêtre Cedex. meyer@vjf.inserm.fr
Gharib
M
M
Lerable
J
J
Sarr
A
A
Boufassa
F
F
Deveau
C
C
Boucherit
S
S
Chaib
A
A
Hubert
J-B
JB
Persoz
A
A
Delfraissy
J-F
JF
Rouzioux
C
C
D023241:Antiretroviral Therapy, Highly Active; D001771:Blood Banks / Q000458:organization & administration*; D001793:Blood Preservation; D015331:Cohort Studies; D015925:Cryopreservation; D005260:Female; D005602:France; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy; D006801:Humans; D008297:Male; D013048:Specimen Handling / Q000379:methods