title: Mining genomic databases to identify novel hydrogen producers.
abstract: The realization that fossil fuel reserves are limited and their adverse effect on the environment has forced us to look into alternative sources of energy. Hydrogen is a strong contender as a future fuel. Biological hydrogen production ranges from 0.37 to 3.3 moles H(2) per mole of glucose and, considering the high theoretical values of production (4.0 moles H(2) per mole of glucose), it is worth exploring approaches to increase hydrogen yields. Screening the untapped microbial population is a promising possibility. Sequence analysis and pathway alignment of hydrogen metabolism in complete and incomplete genomes has led to the identification of potential hydrogen producers.
authors.affiliation: Institute of Genomics and Integrative Biology/CSIR, Delhi University Campus, Mall Delhi Road, 11 00 07, India. vckalia@cbt.res.in
authors.forename: Vipin C
authors.initials: VC
authors.lastname: Kalia
authors.forename: Sadhana
authors.initials: S
authors.lastname: Lal
authors.forename: Rohit
authors.initials: R
authors.lastname: Ghai
authors.forename: Manabendra
authors.initials: M
authors.lastname: Mandal
authors.forename: Ashwini
authors.initials: A
authors.lastname: Chauhan
mesh_terms: D001419:Bacteria / Q000145:classification* / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D003247:Conservation of Natural Resources; D003628:Database Management Systems; D030562:Databases, Protein; D004734:Energy Metabolism / Q000235:genetics; D006859:Hydrogen / Q000378:metabolism*; D006864:Hydrogenase / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D016247:Information Storage and Retrieval / Q000379:methods*; D013045:Species Specificity
chemical_list: D006859:Hydrogen; D006864:Hydrogenase