title: Glutamate carboxypeptidase II inhibition as a novel therapeutic target.
authors.affiliation: Guilford Pharmaceuticals Inc., 6611 Tributary Street, Baltimore, Maryland 21224 USA.
authors.forename: C
authors.initials: C
authors.lastname: Rojas
authors.forename: A G
authors.initials: AG
authors.lastname: Thomas
authors.forename: P
authors.initials: P
authors.lastname: Majer
authors.forename: T
authors.initials: T
authors.lastname: Tsukamoto
authors.forename: X M
authors.initials: XM
authors.lastname: Lu
authors.forename: J J
authors.initials: JJ
authors.lastname: Vornov
authors.forename: K M
authors.initials: KM
authors.lastname: Wozniak
authors.forename: B S
authors.initials: BS
authors.lastname: Slusher
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D001930:Brain Injuries / Q000517:prevention & control; D002268:Carboxypeptidases / Q000378:metabolism*; D004195:Disease Models, Animal; D043425:Glutamate Carboxypeptidase II; D002546:Ischemic Attack, Transient / Q000188:drug therapy; D007668:Kidney / Q000201:enzymology; D018696:Neuroprotective Agents / Q000494:pharmacology / Q000627:therapeutic use; D009943:Organophosphorus Compounds / Q000494:pharmacology / Q000627:therapeutic use; D011480:Protease Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use*
chemical_list: C402107:2-(phosphonomethyl)pentanedioic acid; D018696:Neuroprotective Agents; D009943:Organophosphorus Compounds; D011480:Protease Inhibitors; D002268:Carboxypeptidases; D043425:Glutamate Carboxypeptidase II