The Leyton obsessional inventory - child version in Greek adolescents: standardization in a national school-based survey and two-year follow-up.
OBJECTIVE
The aims of this study were a) to standardize the survey form of the Leyton Obsessional Inventory - Child Version (Leyton-CV) in Greece, and estimate its sensitivity and specificity, and b) to assess high-risk factors for the development of adolescent obsessive-compulsive disorder (OCD) within a two year period.


METHODS
The Leyton-CV was administered to a national, representative, school-based population of 2552 Greek adolescents. Adolescents with a wide range of Leyton-CV scores were interviewed with the SADS-LA to determine the sensitivity and specificity of the instrument. Adolescents with high Leyton scores but no OCD diagnosis, and those with obsessive-compulsive symptoms (OCS), were re-interviewed after two years with the SADS-LA. Family history data on OCD and other mental illness were obtained through the Family Informant Schedule at follow-up.


RESULTS
Using a cut-off point of 35 for the total score, the sensitivity of the Leyton-CV was 79.4 % and the specificity 72.6 %. High Leyton-CV scores and a positive family history for OCD/OCS appeared to constitute high risk factors for later OCD/OCS in adolescents.
Roussos
Alexandra
A
Attiki Child Psychiatric Hospital, Athens, Greece. alrousou@ath.forthnet.gr
Francis
Konstantine
K
Koumoula
Anastasia
A
Richardson
Clive
C
Kabakos
Christos
C
Kiriakidou
Tatiana
T
Karagianni
Stavroula
S
Karamolegou
Kalliopi
K
D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006115:Greece; D006306:Health Surveys; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D010552:Personality Assessment / Q000592:standards* / Q000706:statistics & numerical data; D011594:Psychometrics; D015203:Reproducibility of Results; D012307:Risk Factors