Genetic mechanism and property of a whole-arm translocation (WAT) between chromosomes 8 and 9 of agile gibbons (Hylobates agilis).
C-banding analysis with 47 gibbons of the subgenus Hylobates (Hylobates) (44-chromosome gibbons) uncovered that the gibbons had a characteristic complicated C-banding pattern. The C-band pattern also revealed that a whole-arm translocation (WAT) between chromosomes 8 and 9 existed only in the species H. agilis (agile gibbon). Comprehensive consideration allows postulation that the translocation seemed to be restricted to two subspecies: H. agilis agilis (mountain agile gibbon) and H. agilis unko (lowland agile gibbon), found in Sumatra and part of the Malay Peninsula. Moreover, combined intensive analyses of C-banding and chromosome painting provided strong evidence for a plausible evolutionary pathway of chromosome differentiation of chromosomes 8 and 9. The C-banded morph 8M(t/c) seemed to be the primary type of chromosome 8 in the subgenus and to have altered into the three morphs through three pericentric inversions. The newest morph (8A(M/ci)) produced by the third inversion exchanged the long arm for chromosome 9, and subsequently constructed the WAT morphs of 8/9A(Mc/ct) and 9/8M(i/ci).
Hirai
Hirohisa
H
Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan. hirai@pri.kyoto-u.ac.jp
Mootnick
Alan R
AR
Takenaka
Osamu
O
Suryobroto
Bambang
B
Mouri
Toshio
T
Kamanaka
Yosirou
Y
Katoh
Akira
A
Kimura
Naoto
N
Katoh
Akino
A
Maeda
Norihiko
N
D000818:Animals; D002871:Chromosome Banding; D002875:Chromosomes; D005260:Female; D006922:Hylobates / Q000235:genetics*; D017404:In Situ Hybridization, Fluorescence; D014178:Translocation, Genetic