[A randomized controlled study on the efficacy of modified sclerotherapy in treating angioma of ear, nose and throat].
OBJECTIVE
To evaluate the efficacy and security of modified and traditional sclerotherapy in treating angioma in ENT.


METHODS
For the Angioma of derma and hypodermis (naso face, auricles, neck) 56 cases and 82 cases of mucosa and hypomucosa (the cavities of nose, throat and mouth) were randomized divided into 2 groups each.: The 5% Sodium Morrhate + Triamcinolone Acetonide (The Modified Sclerotherapy n = 28, n = 41) and only 5% Sodium Morrhate (Traditional Sclerotherapy n = 28, n = 41) were respectively injected into bodies of Angioma, as one time a week for 2-6 weeks, on average 19 days.


RESULTS
The rates of cure and effective for Modified and Traditional Sclerotherapies were 84.1%, 65.2% and 91.3%, 85.5% respectively. There is a significant in statistics for effective rates and there is a notable difference in cured rates between the two therapies. It shows that Modified Sclerotherapy has an obvious advantage (P < 0.05). Although the efficacy is similar between the two therapies for angioma of mucosa and hypomucosa, the difference has a significant in efficacy for angioma of derma and hypoderma between the two therapies (P < 0.05) and the side-effects were very slight for Modified Sclerotherapy.


CONCLUSIONS
There is a more prominent efficacy and security for Modified Sclerotherapy than Traditional Sclerotherapy.
Zhou
Kaiyuan
K
Department of Otolaryngology, Huaxi Hospital, Sichuan University, Chengdu 610041.
Liang
Chuanyu
C
Yang
Keqin
K
Wang
Lihong
L
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010039:Otorhinolaryngologic Neoplasms / Q000628:therapy*; D015911:Sclerotherapy; D012976:Sodium Morrhuate / Q000008:administration & dosage; D014222:Triamcinolone Acetonide / Q000008:administration & dosage
D012976:Sodium Morrhuate; D014222:Triamcinolone Acetonide