[Clinical study on treatment of HIV infected persons based on viral load detection and CD4+ T lymphocyte counting].
OBJECTIVE
To study the usage of viral load and CD4+ cell count methods in evaluating the effects of clinical treatment in HIV infected people.


METHODS
Totally 73 cases of HIV infected persons were studied with clinical observation and laboratory examinations, six cases were treated with cocktail therapy, 36 cases with chinese herbs and the other 31 cases were untreated.


RESULTS
The results indicated that the viral load levels in cocktail therapy group were significantly lower than the other two groups within 3 months and then kept at very low level. The CD4+ T lymphocyte levels showed a significant increase after 3 months and kept rising up. The chinese herb group, however, had no significant difference in viral load level and CD4+ T lymphocyte level as compared with untreated group. But in clinical observation chinese herbs showed the effect of improving clinical status in some cases.


CONCLUSIONS
The authors conclude that the viral load and CD4+ count are efficient methods in clinical evaluation of HIV treatment, especially in routine anti-HIV therapy. As for the chinese herbs treatment, these two monitors did not reflect changes in clinical status.
Lin
Xudong
X
National Center for AIDS Prevention and Control, Beijing 100050, China.
Xu
Lianzhi
L
Feng
Yi
Y
Li
Jie
J
Pei
Lijan
L
Shen
Tongqing
T
Shao
Yiming
Y
D019380:Anti-HIV Agents / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D006801:Humans; D008517:Phytotherapy; D016896:Treatment Outcome; D019562:Viral Load
D019380:Anti-HIV Agents; D004365:Drugs, Chinese Herbal