Early neonatal antioxidant capacity after preexisting impaired placental function.
Plasma antioxidant capacity in very preterm infants (n=17), measured as the ferric-reducing ability of plasma (FRAP), increased significantly until day 2 postpartum and decreased thereafter until day 7. Within this period, the FRAP values in matched infants, born after impaired placental function (IPF, n=17), did not change. Their FRAP values were lower and the incidence of oxidative stress-related diseases was significantly higher in these infants.
Wijnberger
Lia D E
LD
Department of Obstetrics, Wilhelmina Children's Hospital Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands.
Krediet
Tannette G
TG
Visser
Gerard H A
GH
van Bel
Frank
F
Egberts
Johannes
J
D000975:Antioxidants / Q000032:analysis*; D001663:Bilirubin / Q000097:blood; D001724:Birth Weight; D005260:Female; D005290:Ferric Compounds / Q000737:chemistry; D017359:HELLP Syndrome / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010922:Placenta Diseases / Q000150:complications*; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D012709:Serum Albumin / Q000032:analysis
D000975:Antioxidants; D005290:Ferric Compounds; D012709:Serum Albumin; D001663:Bilirubin