[The sensitivity of the uropathogenic Escherichia coli strains to antibiotics, bacteriophages and bactericidal serum activity].
Escherichia coli strains isolated from children with urinary tract infections (UTI) were investigated for their sensitivity to antimicrobial drugs, bacteriophages and bactericidal activity of human serum. It has been proved, that the resistance to bactericidal effect of serum is not the dominant feature of uropathogenic Escherichia coli strains. Significant percentage of the strains appeared to be sensitive to the most popular drugs ordered during UTI treatment in children. No simple relationship between sensitivity of the strains to the drug and to the human serum has been found. Three of 44 bacteriophages specific to Escherichia coli have shown the lytic effect towards 50-60% strains under investigations.
Drulis-Kawa
Zuzanna
Z
Zakład Mikrobiologii Ogólnej, Instytut Mikrobiologii Uniwersytetu Wrocławskiego we Wrocławiu, Laboratorium Bakteriologiczne, Dolnoślaskie Centrum Pediatryczne im. J. Korczaka, Wrocławiu.
Weber-Dabrowska
Beata
B
Lewczyk
Ewa
E
Jankowski
Stanisław
S
Doroszkiewicz
Włodzimierz
W
D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use; D001770:Blood Bactericidal Activity; D002648:Child; D003090:Coliphages; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D004926:Escherichia coli / Q000187:drug effects*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology*
D000892:Anti-Infective Agents, Urinary