title: Patterns of changes in temperament and character inventory scales in subjects with obsessive-compulsive disorder following a 4-month treatment.
abstract: OBJECTIVE
  The purpose of this study was to assess changes in the temperament and character patterns in subjects with obsessive-compulsive disorder (OCD) following the treatment for obsessive/compulsive and accompanying depressive symptoms.
  
  
  METHODS
  Study subjects were 35 patients who met the DSM-IV criteria for OCD. All subjects were assessed with the Temperament and Character Inventory (TCI), the Yale-Brown Obsessive-Compulsive Scale, the Beck Depression Inventory, and the Beck Anxiety Inventory before and after a 4-month treatment.
  
  
  RESULTS
  Harm Avoidance (HA) scores in OCD subjects before treatment significantly decreased after treatment. However, the Self-Directedness scores, which were significantly lower than healthy comparison subjects before treatment, did not change. In addition, Reward Dependence scores in OCD subjects, which were not significantly different from healthy comparison subjects before treatment, significantly increased after treatment.
  
  
  CONCLUSIONS
  The TCI pattern of untreated OCD subjects (high HA and low Self-Directedness, relative to healthy comparison subjects) and the decrease of HA scores and no change in Self-Directedness scores following a successful treatment suggest that temperaments are more amenable to treatment than characters.
authors.affiliation: Department of Psychiatry, Seoul National University College of Medicine, Seoul, South Korea.
authors.forename: I K
authors.initials: IK
authors.lastname: Lyoo
authors.forename: T
authors.initials: T
authors.lastname: Yoon
authors.forename: D H
authors.initials: DH
authors.lastname: Kang
authors.forename: J S
authors.initials: JS
authors.lastname: Kwon
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety; D003863:Depression; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000523:psychology* / Q000628:therapy*; D011569:Psychiatric Status Rating Scales; D012649:Self Concept; D013694:Temperament; D016896:Treatment Outcome