[Lymphomatoid papulosis type C or transition to CD30+-T-cell lymphoma? A difficult differential diagnosis].
Lymphomatoid papulosis (LyP) is a recurrent papulonodular eruption, characterized by self-healing skin lesions. While this disorder usually has a benign course, about 10% of the patients develop lymphoproliferative disorders such as CD30+ T cell lymphoma. We report 2 patients with LyP type C. In one case progress to a cutaneous CD30+ large T cell lymphoma could not be excluded. Histologic differentiation between LyP and malignant lymphoma causes considerable problems. In this regard, the evaluation of the clinical course is essential. A long-term follow-up including diagnostic imaging studies is required.
Plettenberg
H
H
Universitätshautklinik, Düsseldorf.
Neumann
N J
NJ
Ruzicka
T
T
Megahed
M
M
D002648:Child; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D017731:Lymphomatoid Papulosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D012867:Skin / Q000473:pathology; D013997:Time Factors