title: Comparison of extracapillary and endocapillary blood flow oxygenators for open heart surgery in dogs: efficiency of gas exchange and platelet conservation.
abstract: The goal of the current study was to compare the efficiency of gas exchange and platelet conservation of a new extracapillary blood flow oxygenator versus an endocapillary blood flow oxygenator during open heart surgery with extracorporeal circulation in dogs. Dilation and remodeling of the right ventricular outflow tract of dogs was performed using a patch graft technique to simulate pulmonary stenosis. Sequential pre- and post-operative blood analysis revealed that gas exchange efficiency and platelet conservation was significantly greater with the extracapillary blood flow oxygenator than with the endocapillary blood flow oxygenator. However, the priming volume of the extracapillary blood flow oxygenator was significantly greater, leading to hemodilution. We conclude that while the extracapillary blood flow oxygenator provided benefits in terms of gas exchange and platelet conservation, development of a smaller extracapillary blood flow type oxygenator to reduce hemodilution effects would be beneficial.
authors.affiliation: Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan.
authors.forename: Katsuichiro
authors.initials: K
authors.lastname: Hoshi
authors.forename: Ryou
authors.initials: R
authors.lastname: Tanaka
authors.forename: Akira
authors.initials: A
authors.lastname: Shibazaki
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Nagashima
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Hirao
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Namiki
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takashima
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Noishiki
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Yamane
mesh_terms: D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary; D001792:Blood Platelets / Q000166:cytology*; D006348:Cardiac Surgical Procedures / Q000662:veterinary*; D004285:Dogs; D005260:Female; D008297:Male; D010100:Oxygen / Q000097:blood*; D010106:Oxygenators / Q000662:veterinary*
chemical_list: D010100:Oxygen