Biosynthesis of the sesquiterpene hodgsonox from the New Zealand liverwort Lepidolaena hodgsoniae.
The incorporation of [1-13C] labelled glucose into hodgsonox, a sesquiterpene epoxide with a unique, doubly allylic ether functionality has been studied in axenic cultures of the liverwort Lepidolaena hodgsoniae. Quantitative 13C NMR spectroscopic analysis showed that the isoprene units are derived exclusively from the methylerythritol phosphate pathway.
Barlow
Anna J
AJ
Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.
Lorimer
Stephen D
SD
Morgan
Ed R
ER
Weavers
Rex T
RT
D002247:Carbon Isotopes; D046508:Culture Techniques / Q000379:methods; D005947:Glucose / Q000737:chemistry / Q000378:metabolism; D035926:Hepatophyta / Q000254:growth & development / Q000378:metabolism*; D009520:New Zealand; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D012717:Sesquiterpenes / Q000737:chemistry / Q000378:metabolism*; D013403:Sugar Phosphates / Q000737:chemistry / Q000378:metabolism
D002247:Carbon Isotopes; D012717:Sesquiterpenes; D013403:Sugar Phosphates; D005947:Glucose