title: Bridging the synthetic and biopolymer worlds with peptide-drug conjugates.
abstract: Roberts and Li break the standard library mold by generating hybrid libraries of small molecules tethered to peptides. Hybrid libraries harness larger chemical and structural diversities and thus represent a new frontier in lead drug discovery.
authors.affiliation: Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Weiss
authors.forename: Richard
authors.initials: R
authors.lastname: Chamberlin
mesh_terms: D001704:Biopolymers / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D015195:Drug Design; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000737:chemistry*
chemical_list: D001704:Biopolymers; D019151:Peptide Library; D010455:Peptides; D004364:Pharmaceutical Preparations