title: [Hypothyroidism in children. 82 cases].
abstract: The hypothyroidism is a frequent endocrinopathos. The authors report a retrospective study of 67 cases gathered at pediatric department of Sfax, during 23 years. 40 boys and 42 girls aged from 1 to 164 months, with an average of 55 months old children. The most clinical symptoms have been the dysmorphic syndrome (81.17%), Huge tongue (59.75%), the T3 is low in 30.48%, the FT4 or the T4 is low in 79% and the TSH is high in 84.14%. All the patients have benefitted a treatment based on thyroidian extract from 1977 to 1984, and since 1985 it was based on L. Thyroxin. The neuropsychiatric prognosis satisfactory in 72% and 28% have a mental delay and 56% a delay in growth. The authors insist on the necessity of doing an early diagnosis and treatment which is the only way and issue leading to a favorable neuropsychiatric evolution.
authors.affiliation: Service de Pediatrie, CHU Hedi Chaker-Sfax, Tunisie.
authors.forename: Mongia
authors.initials: M
authors.lastname: Hachicha
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Mahfoudh
authors.forename: Fatma
authors.initials: F
authors.lastname: Loulou
authors.forename: Hatem
authors.initials: H
authors.lastname: Ben Amar
authors.forename: Sémia
authors.initials: S
authors.lastname: Kolsi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ben Slimen
authors.forename: Sémia
authors.initials: S
authors.lastname: Rekik
authors.forename: Ali
authors.initials: A
authors.lastname: Triki
mesh_terms: D002648:Child; D002658:Developmental Disabilities / Q000209:etiology; D005260:Female; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood; D014416:Tunisia / Q000453:epidemiology
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine