title: Biocompatibility of dental materials used in contemporary endodontic therapy: a review. Part 1. Intracanal drugs and substances.
abstract: Irrigation solutions and intracanal medicaments are used within the root canal to clean and aid in disinfecting the dentinal walls. Although these materials are intended to be contained within the root canal, they invariably contact the periapical tissues, either through inadvertent extrusion through the apex or leaching. This paper is a review on the methodology involved in biocompatibility testing followed by a discussion on biocompatibility of contemporary intracanal drugs and substances used in endodontics.
authors.affiliation: Department of Oral Rehabilitation, School of Dentistry, University of Otago, Dunedin, New Zealand. tina.hauman@stonebow.otago.ac.nz
authors.forename: C H J
authors.initials: CH
authors.lastname: Hauman
authors.forename: R M
authors.initials: RM
authors.lastname: Love
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D003786:Dental Pulp Cavity / Q000187:drug effects; D006801:Humans; D008422:Materials Testing; D010486:Periapical Tissue / Q000187:drug effects; D012387:Root Canal Filling Materials / Q000633:toxicity*; D012388:Root Canal Irrigants / Q000633:toxicity*; D018675:Toxicity Tests
chemical_list: D001672:Biocompatible Materials; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants