title: Guided osteogenesis using synthetic membranes and alloplastic materials: a pilot study.
abstract: OBJECTIVE
  The aim of this study was to develop an experimental model for the assessment of bone augmentation, and in doing so, compare the use of beta-tricalcium phosphate (TCP) bone grafts in combination with Gore-Tex augmentation material (GTAM) and GTAM without TCP.
  
  
  METHODS
  Calvarial sites in eight Sprague Dawley rats were prepared for bone augmentation. Graft materials and Hermann stainless steel bone pins were used for localized bone augmentation. Specimens were subjected to macroscopic and histological evaluation at the sixth week.
  
  
  RESULTS
  Bone formation was significantly higher in the group with the graft support.
  
  
  CONCLUSIONS
  TCP bone grafts used in conjunction with supporting pins may contribute to successful bone regeneration by osseoconduction and by maintaining the membrane-created space. At the sixth week, guided bone regeneration utilizing Gore-Tex augmentation material and TCP bone grafts resulted in the formation of viable new bone.
authors.affiliation: Faculty of Dentistry, Department of Oral Surgery, Istanbul University, Istanbul, Turkey. buketaybar@hotmail.com
authors.forename: Buket
authors.initials: B
authors.lastname: Aybar
authors.forename: Omer
authors.initials: O
authors.lastname: Günhan
authors.forename: Levent
authors.initials: L
authors.lastname: Bilgiç
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Emes
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation; D002130:Calcium Phosphates; D048091:Guided Tissue Regeneration / Q000379:methods*; D008297:Male; D008567:Membranes, Artificial; D010865:Pilot Projects; D011138:Polytetrafluoroethylene; D051381:Rats; D017207:Rats, Sprague-Dawley; D012886:Skull; D018709:Statistics, Nonparametric
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D008567:Membranes, Artificial; C485817:beta-tricalcium phosphate; D011138:Polytetrafluoroethylene; C018392:tricalcium phosphate