title: Primary heterologous carcinosarcoma of the ureter with necrotic malignant polyps. Report of a case and review of the literature.
abstract: Carcinosarcoma is a rare and aggressive disease characterized by biphasic neoplasms with distinct mesenchymal and epithelial components. We report a case of ureteral carcinosarcoma with malignant necrotic polyps. The patient was a 58-year-old woman with painless hematuria, who was later diagnosed as having ureteral carcinosarcoma. Three long pendulous polypoid-shape tumors consisting of high-grade transitional cell carcinoma with chondrosarcomatous and osteosarcomatous elements were found. Two months after nephroureterectomy, the tumor relapsed in the bladder. Despite anterior exenteration, the patient died of local recurrence 6 months after her initial visit. To our knowledge, only 10 cases of this disease have been reported in the literature.
authors.affiliation: Department of Urology, Uji Tokushukai Hospital, Kyoto, Japan. johnin@belle.shiga-med.ac.jp
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Johnin
authors.forename: Takashi
authors.initials: T
authors.lastname: Kadowaki
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kushima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ushida
authors.forename: Shuichi
authors.initials: S
authors.lastname: Koizumi
authors.forename: Yusaku
authors.initials: Y
authors.lastname: Okada
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000453:epidemiology / Q000473:pathology*; D002296:Carcinosarcoma / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000453:epidemiology / Q000473:pathology*; D014513:Ureter / Q000473:pathology; D014516:Ureteral Neoplasms / Q000453:epidemiology / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology