[Seroepidemiologic survey of hepatitis G virus in selected population of Shanxi, Qinghai and Xinjiang Provinces (region) of China].
OBJECTIVE
To observe the serological features of hepatitis G virus (HGV or GBV) in selected population of Shaanxi, Qinghai and Xinjiang Provinces (region).


METHODS
Enzyme-linked immunosorbent assay (ELISA) was used to determine IgG antibody against GBV (anti-GBV IgG) in serum specimens of 1469 individuals from the 3 provinces (region).


RESULTS
The positivity rate of serum GBV-IgG antibody in ethnic minorities (4.11% in Tibetan, 5.36% in Mongolian, 4.55% in Uigur, 4.00% in Hui population) was slightly higher than that in Han population (1.36%-1.73%), but the differences were not significant (P>0.05). The positivity rate of serum GBV-IgG antibody in drug abusers (11.30%, 34/301) was remarkably higher than that of the normal population (2.44%,18/736) (P<0.01). The positivity rate of serum GBV-IgG antibody in blood donors was 1.02%-7.68%.


CONCLUSIONS
The positivity rates of serum GBV-IgG antibody among ethnic groups in the 3 provinces (region) had no significant differences; blood-borne transmission seemed to be an important transmission route of GBV, therefore supervision of blood donors and drug abusers should be intensified.
Cao
Maokai
M
Xi'an Jiaotong University, Xi'an 710049, China.
Liu
Fuping
F
Jiang
Shuangying
S
Shao
Xiru
X
Lan
Kexue
K
Li
Xinlan
X
Zhang
Zhenxue
Z
Wang
Wen
W
Zhao
Wenmig
W
Huang
Ruihua
R
D000914:Antibodies, Viral / Q000097:blood*; D001782:Blood Donors; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D018178:Flaviviridae Infections / Q000453:epidemiology* / Q000635:transmission; D029407:GB virus C / Q000276:immunology*; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D016036:Seroepidemiologic Studies; D019966:Substance-Related Disorders / Q000821:virology
D000914:Antibodies, Viral; D007074:Immunoglobulin G