title: Performance evaluation of the Sysmex XT-2000i automated hematology analyzer.
abstract: The Sysmex XT-2000i automated hematology analyzer was evaluated at Saint Louis Children's Hospital (SLCH), St. Louis, MO, USA. Complete blood count results from the Sysmex XT-2000i were compared to results from the Sysmex XE-2100 for 114 pediatric and adult patient samples. Manual differentials were performed on each specimen by 2 experienced medical technologists using guidelines established in the National Committee for Clinical Laboratory Standards (NCCLS) document H20-A. Carryover, precision, linearity, correlation, stability, and mixing-test studies were also performed. The XT-2000i results showed excellent correlation with the results from the XE-2100 for the following parameters: white blood cells; red blood cells; hemoglobin; hematocrit; mean corpuscular volume; mean corpuscular hemoglobin; mean corpuscular hemoglobin concentration; red blood cell distribution width by standard deviation; red blood cell distribution width by coefficient of variation; mean platelet volume; platelets; percent neutrophils, lymphocytes, monocytes, eosinophils, and basophils; and reticulocyte percent and number. In our evaluation of the XT-2000i the correlation coefficients for all complete blood counts and differential parameters compared well with those of the XE-2100. We concluded that the XT-2000i demonstrated comparable analytical performance to its predecessor, the XE-2100.
authors.affiliation: Saint Louis Children's Hospital Core Laboratory/Hematology, St. Louis, Missouri 63110-1077, USA. kxl6966@bjc.org
authors.forename: K
authors.initials: K
authors.lastname: Langford
authors.forename: L
authors.initials: L
authors.lastname: Luchtman-Jones
authors.forename: R
authors.initials: R
authors.lastname: Miller
authors.forename: D
authors.initials: D
authors.lastname: Walck
mesh_terms: D000328:Adult; D001772:Blood Cell Count / Q000295:instrumentation* / Q000592:standards; D002138:Calibration; D002648:Child; D001330:Electronic Data Processing; D006402:Hematologic Diseases / Q000097:blood / Q000175:diagnosis; D006801:Humans; D007202:Indicators and Reagents; D007755:Laboratories, Hospital; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012984:Software
chemical_list: D007202:Indicators and Reagents