Distal airways in humans: dynamic hyperpolarized 3He MR imaging--feasibility.
Dynamic hyperpolarized helium 3 (3He) magnetic resonance (MR) imaging of the human airways is achieved by using a fast gradient-echo pulse sequence during inhalation. The resulting dynamic images show differential contrast enhancement of both distal airways and the lung periphery, unlike static hyperpolarized 3He MR images on which only the lung periphery is seen. With this technique, up to seventh-generation airway branching can be visualized.
Tooker
Angela C
AC
Department of Radiology, Brigham and Women's Hospital, 221 Longwood Ave, Boston, MA 02115, USA.
Hong
Kwan Soo
KS
McKinstry
Erin L
EL
Costello
Philip
P
Jolesz
Ferenc A
FA
Albert
Mitchell S
MS
D000328:Adult; D005240:Feasibility Studies; D005260:Female; D006371:Helium; D006801:Humans; D007554:Isotopes; D008168:Lung / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male
D007554:Isotopes; D006371:Helium