title: Paravertebral block: an alternative to general anesthesia in breast cancer surgery.
abstract: Alternative forms of anesthesia in breast cancer patients have been sought to reduce the untoward effects of general anesthesia. The purpose of this study was to compare paravertebral block (PVB) and general anesthesia (GA) in terms of pain control, postoperative nausea and vomiting, and resumption of diet in patients undergoing operations for breast cancer. A retrospective chart review was performed on all patients (289) undergoing breast cancer surgery from May 1, 1999 through December 31, 2000 with PVB or GA. The PVB (n = 128) and GA (n = 100) groups had similar demographics. Postoperative narcotics were given to 80.8 and 93 per cent of PVB and GA patients, respectively (P < 0.01), after an average of 216 and 122 minutes from the end of surgery (P = 0.028). The PVB group received 6.2 narcotic units compared with 10.1 in the GA group (P = 0.04). Postoperative nausea and vomiting was present in 16.8 and 24 per cent of patients in the PVB and GA groups, respectively (P = 0.12). A diet was tolerated on the same day of surgery by 98.4 and 82 per cent of PVB and GA patients, respectively (P < 0.01). The complication rate of PVB was 1.8 per cent. PVB resulted in better postoperative pain control and earlier resumption of diet compared with GA. The good success rate and low complication rate of PVB make it well suited for breast cancer surgery and can eliminate the need for GA in patients with serious comorbidities.
authors.affiliation: Department of Surgery, Gundersen Lutheran Medical Center, La Crosse, Wisconsin 54601, USA.
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Najarian
authors.forename: Jeanne M
authors.initials: JM
authors.lastname: Johnson
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Landercasper
authors.forename: Paul
authors.initials: P
authors.lastname: Havlik
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Lambert
authors.forename: David
authors.initials: D
authors.lastname: McCarthy
mesh_terms: D000768:Anesthesia, General; D000772:Anesthesia, Local; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology; D020250:Postoperative Nausea and Vomiting / Q000209:etiology