title: [Spontaneous spleen rupture associated to active cytomegalovirus infection].
abstract: We present a 24 year old immunocompetent male who developed a spontaneous rupture of the spleen (SRE) during an acute cytomegalovirus (CMV) infection. The only previous clinical feature was the presence of flu-like symptoms two weeks before the SRE. The diagnosis was confirmed by the presence of IgM antibodies to CMV in the serum and a positive CMV-PCR in the splenic biopsy after splenectomy. The patient recovered completely after surgery. Spontaneous splenic rupture is an uncommon event associated with primary cytomegalovirus infection, and this is the first case reported in our country.
authors.affiliation: Sección Hematología, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Hospital Universitario, Buenos Aires. pduarte1@hotmail.com
authors.forename: Patricio J
authors.initials: PJ
authors.lastname: Duarte
authors.forename: Marcela
authors.initials: M
authors.lastname: Echavarría
authors.forename: Andrea
authors.initials: A
authors.lastname: Paparatto
authors.forename: Roberto
authors.initials: R
authors.lastname: Cacchione
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D016133:Polymerase Chain Reaction; D012422:Rupture, Spontaneous / Q000821:virology; D013156:Splenectomy; D013161:Splenic Rupture / Q000821:virology*
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M