title: [Study on the incidence and risk factors for in-hospital stroke in patients with acute myocardial infarction].
abstract: OBJECTIVE
  To determine the incidence and risk factors for in-hospital stroke in patients with acute myocardial infarction (AMI).
  
  
  METHODS
  Two thousand one hundred and thirty-three patients with acute myocardial infarction were studied retrospectively. History, demographic, clinical, thrombolytic and anticoagulant data of AMI were obtained through review of the medical record. The relative risk of in-hospital stroke in patients with AMI was estimated using multiple nonconditional logistic regression to adjust for potential confounding factors.
  
  
  RESULTS
  Among 2,133 consecutive patients admitted with acute myocardial infarction to hospitals in Shandong and Hubei provinces, 98 (4.59%) experienced strokes during hospitalization. In our analysis, anterior infarction was the most important risk factor for in-hospital stroke (ischemic and hemorrhagic) in patients with AMI (RR = 7.04), followed by history of hypertension (RR = 3.41), previous stroke (RR = 1.69), atrial fibrillation (RR = 2.22), advanced age (RR = 1.04), and higher heart rate at enrollment (RR = 1.03).
  
  
  CONCLUSIONS
  The incidence of in-hospital stroke in patients with AMI increased with lower rate of using thrombolytic agents. Thrombolytic therapy was noticed as a protective factor for stroke after AMI. The risk factors for in-hospital stroke with AMI were history of hypertension, previous stroke, atrial fibrillation, advanced age, anterior infarction, and higher heart rate at enrollment.
authors.affiliation: Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
authors.forename: Yansheng
authors.initials: Y
authors.lastname: Pi
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Luyuan
authors.initials: L
authors.lastname: Shi
authors.forename: Ruifang
authors.initials: R
authors.lastname: Wang
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Xia
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications*; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology