title: Chemistry and biology of new marine alkaloids from the indole and annelated indole series.
abstract: Chemistry and biology of marine natural products from the indole and annelated indole series have become an attractive research field for development of new pharmacological lead substances. In the past years some of the isolated natural organic compounds were synthesized by chemists and evaluated with great enthusiasm to find new lead natural compounds against different diseases. In this review the latest results for new compounds including isolation, biological evaluation, synthetic pathways and some retrosynthetic analyses are summarized.
authors.affiliation: Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Mainz, D-55099 Mainz, Germany.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Aygün
authors.forename: Ulf
authors.initials: U
authors.lastname: Pindur
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008386:Marine Biology; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000302:isolation & purification; D013329:Structure-Activity Relationship
chemical_list: D000470:Alkaloids; D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D001685:Biological Factors; D007211:Indoles; D004364:Pharmaceutical Preparations