[Antiphospholipid antibodies in acute coronary syndrome].
The authors examined the presence of antiphospholipid antibodies in acute coronary syndrome. As their results show the frequency of antibodies against B2-glycoprotein I is significantly higher (14.4%) than the presence of these antibodies in a healthy control group (2%). Occurrence of antibodies against B2-glycoprotein I is much more higher than the occurrence of IgG- or IgM type antibodies against cardiolipin or lupus anticoagulant.


CONCLUSIONS
The authors emphasize the possible role of anti-B2-glycoprotein I antibodies in thrombotic process of acute coronary syndrome. The previous ischaemic stroke was significantly more frequent in those patients medical history in whose serums antibodies against B2-glycoprotein I were present, so the presence of this thrombophil factor in acute coronary syndrome points out the importance of secunder antithrombotic prevention.
Soltész
Pál
P
Debreceni Egyetem Orvos- és Egészségtudományi Centrum Altalános Orvostudományi Kar, III. sz. Belgyógyászati Klinika. soltesz@iiibel.dote.hu
Veres
Katalin
K
Lakos
Gabriella
G
Kerényi
Adrienn
A
Szegedi
Gyula
G
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D001323:Autoantibodies / Q000097:blood; D002308:Cardiolipins / Q000276:immunology; D003327:Coronary Disease / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D005260:Female; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013577:Syndrome
D017152:Antibodies, Antiphospholipid; D001323:Autoantibodies; D002308:Cardiolipins; D006023:Glycoproteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M