title: [Lymphoscintigraphy in sentinel lymph node biopsy of breast cancer].
abstract: OBJECTIVE
  To evaluate the feasibility of lymphoscintigraphy in sentinel lymph node biopsy of breast cancer.
  
  
  METHODS
  Lymphoscintigraphy was performed after peritumoral or subdermal injection of radioactive colloid. Then, sentinel lymph node (SLN) biopsy guided by gamma detector probe was performed. Factors correlated with identification-detection rate were assessed.
  
  
  RESULTS
  Lymphatic drainage was present in preoperative lymphoscintigraphy in 88(93%) out of 95 patients, with 39 (44.3%) positive for lymphatic drainage other than in the axilla. A total of 91 (95.8%) patients had their SLN identified in the intraoperative procedure. The quality of lymphoscintigraphic image was closely related to SLN identification-detection rate in the intraoperative procedure (P = 0.025).
  
  
  CONCLUSIONS
  Sentinel lymph node outside the axilla can be detected by lymphoscintigraphy. The combination of lymphoscintigraphy and gamma detector probe for sentinel lymph node biopsy of breast cancer not only is acceptable but promising.
authors.affiliation: Department of Breast Surgery and Nuclear Medicine, Cancer Hospital (Institute), Fu Dan University, Shanghai 200032, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Kunwei
authors.initials: K
authors.lastname: Shen
authors.forename: Lamichhane
authors.initials: L
authors.lastname: Nirmal
authors.forename: Guangyu
authors.initials: G
authors.lastname: Liu
authors.forename: Jiong
authors.initials: J
authors.lastname: Wu
authors.forename: Yingjian
authors.initials: Y
authors.lastname: Zhang
authors.forename: Huifeng
authors.initials: H
authors.lastname: Du
authors.forename: Zhangchi
authors.initials: Z
authors.lastname: Pan
authors.forename: Zhimin
authors.initials: Z
authors.lastname: Shao
authors.forename: Zhenzhou
authors.initials: Z
authors.lastname: Shen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001365:Axilla; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008198:Lymph Nodes; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy