Management of intracranial aneurysms: factors that influence clinical grade and surgical outcome.
BACKGROUND
We report the experience in managing intracranial aneurysms at our medical center.


METHODS
We retrospectively analyzed 297 intracranial aneurysms managed during a 6-year period. Risk factors were analyzed with respect to their influence on outcome after surgery as measured by Glasgow Outcome Scale score.


RESULTS
Fifty-eight patients had multiple aneurysms. Of all aneurysms, 83% were in the anterior circulation, 37% were unruptured, and 59% were larger than 10 mm in size. Good outcomewas achieved in 75% of patients, and another 16% had fair outcomes. The mortality rate was 4%, and significant morbidity occurred in 5% of patients. Significant indicators of poor outcome were worsened clinical grade, posterior aneurysm location, and large aneurysm size.


CONCLUSIONS
Hypertensive patients, older patients, and patients with posterior circulation aneurysms had poorer neurologic status, which significantly influenced outcome. Larger aneurysms and vertebrobasilar aneurysms were associated with poor outcomes.
Nanda
Anil
A
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA. ananda@lsuhsc.edu
Vannemreddy
Prasad
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008145:Louisiana / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome