title: [Antiphospholipid antibodies in HELLP syndrome: clinical and biological study in 68 women].
abstract: OBJECTIVE
  Pregnancy complicated by the HELLP syndrome and antiphospholipid syndrome have rarely been reported. We report a study on anticardiolipin antibodies in HELLP syndrome.
  
  
  METHODS
  Between March 1996 and September 1999, anticardiolipin antibodies were checked in all women with HELLP syndrome hospitalised in a maternity of the North of France. The women with positive anticardiolipin antibodies were seen month later in a internal medicine department.
  
  
  RESULTS
  In the period 68 women with HELLP syndrome were checked for anticardiolipin antibodies. Apl were present in 9 patients (Incidence 42.8/1000 HELLP Year). They persisted after the accident only in 3 patients. Antiphospholipid syndrome was diagnosed in 2 patients, prevalence between the HELLP syndrome for the 42 month period was 0.03.
  
  
  CONCLUSIONS
  HELLP syndrome may be a manifestation linked to the antiphospholipid syndrome and may revealed it.
authors.affiliation: Service de médecine interne, hôpital Claude-Huriez, CHRU de Lille, rue Polonovski, 59037 cedex, Lille, France. v-queyrel@chru-lille.fr <v-queyrel@chru-lille.fr>
authors.forename: V
authors.initials: V
authors.lastname: Queyrel
authors.forename: A-S
authors.initials: AS
authors.lastname: Ducloy-Bouthors
authors.forename: U
authors.initials: U
authors.lastname: Michon-Pasturel
authors.forename: E
authors.initials: E
authors.lastname: Hachulla
authors.forename: S
authors.initials: S
authors.lastname: Dubucquoi
authors.forename: C
authors.initials: C
authors.lastname: Caron
authors.forename: A-S
authors.initials: AS
authors.lastname: Vallat
authors.forename: D
authors.initials: D
authors.lastname: Subtil
authors.forename: P
authors.initials: P
authors.lastname: Dufour
authors.forename: M
authors.initials: M
authors.lastname: Lambert
authors.forename: P-Y
authors.initials: PY
authors.lastname: Hatron
authors.forename: B
authors.initials: B
authors.lastname: Devulder
authors.forename: F
authors.initials: F
authors.lastname: Puech
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis* / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000276:immunology* / Q000473:pathology; D005260:Female; D017359:HELLP Syndrome / Q000276:immunology* / Q000473:pathology; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D017152:Antibodies, Antiphospholipid