title: Challenges to cancer control by screening.
abstract: Population-based screening seems to be a common-sense strategy for controlling cancer, but recent reports have raised controversy concerning the benefits of common screening procedures. Intense efforts to develop and evaluate novel screening technologies are underway; however, effective use of any screening method must take into account any underlying biological considerations. What are these biological issues, and what challenges do clinicians face in screening for common cancers?
authors.affiliation: Programs of Cancer Prevention and Cancer Genetics, McGill University, Montreal, Quebec, Canada H3T 1E2. michael.pollak@mcgill.ca
authors.forename: Michael N
authors.initials: MN
authors.lastname: Pollak
authors.forename: William D
authors.initials: WD
authors.lastname: Foulkes
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008403:Mass Screening / Q000191:economics / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D012680:Sensitivity and Specificity; D016019:Survival Analysis
chemical_list: D014408:Biomarkers, Tumor