Tuberculosis of the nasopharynx: a rare entity revisited.
OBJECTIVE
Tuberculosis of the nasopharynx is uncommon. A large series of 17 cases is reported, and the clinical and pathological features are discussed.


METHODS
A retrospective review.


METHODS
Seventeen archived cases of biopsy-proven nasopharyngeal tuberculosis were reviewed for patient age and sex, presenting complaint and duration, systemic symptoms, cervical lymphadenopathy, and chest x-ray findings. These findings were compared with a compilation of 40 cases reported in the English literature.


RESULTS
There was a female predominance (13 women and 4 men), with age range of 20 to 74 years (mean age, 38 y). The most common presentation was enlargement of the cervical lymph nodes (53%), followed by hearing loss (12%), tinnitus, otalgia, nasal obstruction, and postnasal drip (6% each). The duration of the presenting symptoms ranged from 1 week to 1 year (mean duration, 16 wk). Ten patients (59%) had cervical lymphadenopathy, two (12%) had systemic symptoms (fever, weight loss, night sweats), and one patient (6%) had miliary pulmonary tuberculosis. Direct endoscopic examination showed nasopharyngeal mucosal irregularity or mass in the majority of patients (12 patients [70%]). These features were similar to those reported in the literature.


CONCLUSIONS
Nasopharyngeal tuberculosis is uncommon, usually occurring without pulmonary or systemic involvement. Cervical lymphadenopathy occurs in more than half of the patients and is the most common presenting complaint; this, together with the nasopharyngeal findings of mass or mucosal irregularity, makes differentiation from carcinoma on clinical examination difficult, necessitating histological evaluation.
Tse
Gary M K
GM
Department of Anatomical and Cellular Pathology, Division of Otorhinolaryngology, Prince of Wales Hospital, Chinese University of Hong Kong, Republic of China. garytse@cuhk.edu.hk
Ma
Tony K F
TK
Chan
Amy B W
AB
Ho
Fiona N Y
FN
King
Ann D
AD
Fung
Kitty S C
KS
Ahuja
Anil T
AT
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D009302:Nasopharyngeal Diseases / Q000150:complications / Q000473:pathology*; D009333:Neck; D012189:Retrospective Studies; D014376:Tuberculosis / Q000150:complications / Q000473:pathology*