PGG2, 11R-HPETE and 15R/S-HPETE are formed from different conformers of arachidonic acid in the prostaglandin endoperoxide H synthase-1 cyclooxygenase site.
Thuresson
Elizabeth D
ED
Department of Biochemistry, Michigan State University, East Lansing, MI 48824, USA.
Lakkides
Karen M
KM
Smith
William L
WL
D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism*; D019556:COS Cells; D002522:Chlorocebus aethiops; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000737:chemistry / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008565:Membrane Proteins; D008861:Microsomes / Q000201:enzymology; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D011462:Prostaglandins G / Q000737:chemistry / Q000378:metabolism*; D011994:Recombinant Proteins; D012669:Seminal Vesicles / Q000201:enzymology; D013237:Stereoisomerism; D013379:Substrate Specificity; D014162:Transfection
D006893:Hydroxyeicosatetraenoic Acids; D007527:Isoenzymes; D008565:Membrane Proteins; D011462:Prostaglandins G; D011994:Recombinant Proteins; D016718:Arachidonic Acid; C038291:prostaglandin G2; C027356:11-hydroxy-5,8,12,14-eicosatetraenoic acid; C025984:15-hydroxy-5,8,11,13-eicosatetraenoic acid; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; C496511:PTGS1 protein, human; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases