Use of equivocal zone in interpretation of results of the amplified mycobacterium tuberculosis direct test for diagnosis of tuberculosis.
The sensitivity and specificity of the Amplified Mycobacterium Tuberculosis Direct (AMTD) test, evaluated with 1,363 respiratory samples (128 from tuberculous patients), were 92.97 and 98.7%, respectively. When an equivocal zone (30,000 to 1,000,000 relative light units [RLU]) was used instead of a 30,000-RLU cutoff, the sensitivity and specificity of the AMTD test were 92.97 and 100%, respectively.
Kerleguer
A
A
HIA Val de GrAce, 75005 Paris. HIA Percy, 92140 Clamart. HIA Desgenettes, 69003 Lyon, France. alexandrakerleguer@net-up.com
Koeck
J-L
JL
Fabre
M
M
Gérôme
P
P
Teyssou
R
R
Hervé
V
V
D015342:DNA Probes; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D012329:RNA, Bacterial / Q000302:isolation & purification; D012335:RNA, Ribosomal / Q000235:genetics; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology*
D015342:DNA Probes; D012329:RNA, Bacterial; D012335:RNA, Ribosomal