title: Endoscopic miniprobe ultrasonography in diagnosis of carcinomas and submucosal tumors of large intestine.
abstract: OBJECTIVE
  To assess the value of endoscopic miniprobe ultrasonography in the diagnosis of carcinomas and submucosal tumors of the large intestine.
  
  
  METHODS
  A total of 96 patients with carcinomas and submucosal tumors of the large intestine were given colonoscopic ultrasonography with a miniprobe (Olympus UM-2R, 12 MHz; UM-3R, 20 MHz) from December, 2000 to January, 2002.
  
  
  RESULTS
  Carcinomas of the large intestine of 81 patients appeared as a hypoechoic mass under endoscopic ultrasonography, by which 67 patients (82.7%) were accurately diagnosed as having infiltrated colorectal carcinomas. The sensitivity of endoscopic ultrasonography in the diagnosis of lymph node metastasis was 55.4%, while the specificity was 68.8%. The positive predictive value and the negative predictive value were 0.88 and 0.28, respectively. All 15 cases with submucosal tumors were diagnosed correctly under endoscopic ultrasonography except for one leiomyoma, which was misdiagnosed as leiomyosarcoma.
  
  
  CONCLUSIONS
  Endoscopic miniprobe ultrasonography has a high accuracy in determining the invasion depth of carcinomas of the large intestine and the diagnosis of submucosal tumors. The pre-operative endoscopic ultrasonography may provide valuable information and influence the choice of therapy for carcinomas and submucosal tumors of the large intestine.
authors.affiliation: Department of General Surgery, ZhongShan Hospital, Fudan University, Shanghai 200032, China. chow@zshospital.net
authors.forename: Pinghong
authors.initials: P
authors.lastname: Zhou
authors.forename: Liqing
authors.initials: L
authors.lastname: Yao
authors.forename: Fenglin
authors.initials: F
authors.lastname: Liu
authors.forename: Xinyu
authors.initials: X
authors.lastname: Qin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D014463:Ultrasonography