title: [Prognosis of infectious endocarditis].
abstract: OBJECTIVE
  To study clinical course and prognostic factors of infective endocarditis.
  
  
  METHODS
  Infective endocarditis was identified in 126 consecutive patients (criteria of DURACK). Of these, 73 were male, mean age was 29.9 + 15 years, 98 (77.7%) had past history of cardiac disease. The evolution has been marked by 38 deaths (30%) in spite of the recourse to surgery (69 patients). The mean follow-up period was 52 months, the event-free survival was 61% at 5 years.
  
  
  RESULTS
  By univariate analysis the predictors of bad prognosis: Large vegetations > 10 mm, delay of apyrexia > 10 days presence of a neurological accident and the absence of surgical treatment. Multivariate analysis: Vegetation > 10 mm (OR 1.97, 1-4.1, p = 0.05), presence of a neurological accident (OR:2.76, 1.32-5.76, p = 0.007) and the absence of surgical treatment (OR: 5.03, 2-11.4, p < 0.001).
  
  
  CONCLUSIONS
  Infective endocarditis remains a serious affection, identification of patients with poor prognosis should lead to early surgical referral: this attitude provides good immediate and long-term results.
authors.affiliation: Service de Cardiologie Centre Hospitalo-Universitaire F Bourguiba de Monastir.
authors.forename: Hamda K
authors.initials: HK
authors.lastname: Ben
authors.forename: F
authors.initials: F
authors.lastname: Betbout
authors.forename: F
authors.initials: F
authors.lastname: Addad
authors.forename: H
authors.initials: H
authors.lastname: Gamra
authors.forename: F
authors.initials: F
authors.lastname: Maatouk
authors.forename: Z
authors.initials: Z
authors.lastname: Dridi
authors.forename: M A
authors.initials: MA
authors.lastname: Zidi
authors.forename: R
authors.initials: R
authors.lastname: Hammouda
authors.forename: Farhat M
authors.initials: FM
authors.lastname: Ben
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D018572:Disease-Free Survival; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D005260:Female; D017052:Hospital Mortality; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011237:Predictive Value of Tests; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014416:Tunisia / Q000453:epidemiology