title: Three-dimensional terahertz pulse imaging of dental tissue.
abstract: There are unresolved clinical problems that require the provision of accurate 3-D images of tissue structures such as teeth. In particular, measurements of dental enamel thickness are necessary to quantify problems associated with enamel erosion, yet currently there is no nondestructive method to obtain this information. We present a method that relies on the use of pulsed terahertz radiation to gain 3-D information from dental tissues. We discuss results from 14 samples and demonstrate that we can reliably and accurately quantify enamel thickness. We show that in a series of 22 surfaces, we can image pertinent subsurface features 91% of the time. Example images are shown where structures in teeth at depth are rendered accurate to within 10 microm. We discuss issues that arise using this imaging method and propose ways in which it could be used in clinical practice.
authors.affiliation: University of Cambridge, Cavendish Laboratory, Cambridge, United Kingdom and Tera View Limited, Cambridge Science Park, Cambridge, United Kingdom.
authors.forename: David
authors.initials: D
authors.lastname: Crawley
authors.forename: Christopher
authors.initials: C
authors.lastname: Longbottom
authors.forename: Vincent P
authors.initials: VP
authors.lastname: Wallace
authors.forename: Bryan
authors.initials: B
authors.lastname: Cole
authors.forename: Don
authors.initials: D
authors.lastname: Arnone
authors.forename: Michael
authors.initials: M
authors.lastname: Pepper
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D066298:In Vitro Techniques; D007180:Incisor / Q000166:cytology*; D008872:Microwaves; D012815:Signal Processing, Computer-Assisted