Adaptive designs for sequential experiments.
Various adaptive designs have been proposed and applied to clinical trials, bioassay, psychophysics, etc. Adaptive designs are also useful in high cost engineering trials. More and more people have been paying attention to these design methods. This paper introduces several broad families of designs, such asthe play-the-winner rule, randomized play-the-winner rule and its generalization to the multi-arm case, doubly biased coin adaptive design, Markov chain model.
Lin
Zheng-Yan
ZY
Department of Mathematics, Zhejiang University, Hangzhou 310028, China. zlin@mail.hz.zj.cn
Zhang
Li-Xin
LX
D002986:Clinical Trials as Topic / Q000145:classification* / Q000379:methods*; D005246:Feedback; D006801:Humans; D008390:Markov Chains; D015233:Models, Statistical; D018579:Patient Selection; D011786:Quality Control; D012107:Research Design; D018401:Sample Size; D015983:Selection Bias; D016896:Treatment Outcome