title: [Neuroprotective effect of Betoptic S-considerations after 18 months of treatment].
abstract: BACKGROUND
  The aim of our study was the analysis of the hypotensor and neuroprotector effect induced by Betoptic S given to patients diagnosed with open-angled glaucoma.
  
  
  METHODS
  A set of patients with open-angled glaucoma at different stages of evolution, during a period of 18 months were available for our examination. We took in to account parametres such as: ocular pressure values, fundus examination, kinetic and automatic perimetry.
  
  
  RESULTS
  Betoptic S treatment in patients with open-angled glaucoma in early stages was efficient; therefore ocular pressure values continued in normal limits and visual capacity at automatic perimetry was improved. A number of patients in which Betoptic S didn't cause an ocular pressure compensation were given Xalatan. This association was a beneficial one. In those patients with open-angled glaucoma in terminal stage Betoptic S and Xalatan association was inefficient. In those patients which were not treated at all, visual capacity decreased to zero.
  
  
  CONCLUSIONS
  1. Betoptic S neuroprotector effect is obvious in early glaucoma patients; visual capacity was improved in all cases. 2. In advanced and terminal stages of the disease visual capacity goes on decreasing in spite of the associated treatment.
authors.forename: Florica
authors.initials: F
authors.lastname: Ignat
authors.forename: Carmen
authors.initials: C
authors.lastname: Damian
authors.forename: Rodica
authors.initials: R
authors.lastname: Mănescu
authors.forename: Ilia
authors.initials: I
authors.lastname: Perovic
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D015784:Betaxolol / Q000627:therapeutic use*; D003196:Computer Graphics; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D015784:Betaxolol