title: Physical fitness and plasma non-enzymatic antioxidant status at rest and after a wingate test.
abstract: We tested seven physical education students whether 30-s sprint anaerobic exercise (Wingate test) would result in oxidative stress (evaluated by lipid radical levels) sufficient to alter plasma non-enzymatic antioxidant status (plasma uric acid, ascorbic acid, alpha-tocopherol, beta-carotene). This study demonstrates that 1) Wingate test increases plasma uric and ascorbic acid concentrations (p <.05), and decreases plasma alpha-tocopherol and beta-carotene levels (p <.05); 2) lipid radical levels at rest and sprint performance are negatively correlated with resting plasma uric acid and alpha-tocopherol concentrations (p <.05). In conclusion, this study 1) demonstrates that a 30-s sprint anaerobic exercise is associated with acute changes in plasma non-enzymatic antioxidant status, 2) indicates that the subjects with largest leg peak power are those who exhibit the lowest plasma antioxidant status at rest (uric acid and alpha-tocopherol), 3) and suggests that antioxidant intake by maintaining plasma antioxidant concentration at rest in the normal range might protect athletes against oxidative stress induced by exercise.
authors.affiliation: Laboratoire de Physiologie et de Biomechanique de l'Exercice Musculataire, UFRAPS, University de Rennes 2, Rennes Cedex, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Groussard
authors.forename: Guillaume
authors.initials: G
authors.lastname: Machefer
authors.forename: FrançOise
authors.initials: F
authors.lastname: Rannou
authors.forename: Henri
authors.initials: H
authors.lastname: Faure
authors.forename: Hassane
authors.initials: H
authors.lastname: Zouhal
authors.forename: Odile
authors.initials: O
authors.lastname: Sergent
authors.forename: Martine
authors.initials: M
authors.lastname: Chevanne
authors.forename: Josiane
authors.initials: J
authors.lastname: Cillard
authors.forename: Arlette
authors.initials: A
authors.lastname: Gratas-Delamarche
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000975:Antioxidants / Q000378:metabolism*; D001205:Ascorbic Acid / Q000097:blood; D001642:Bicycling / Q000502:physiology; D005080:Exercise Test; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D018384:Oxidative Stress; D010809:Physical Fitness; D014527:Uric Acid / Q000097:blood; D024502:alpha-Tocopherol / Q000097:blood; D019207:beta Carotene / Q000097:blood
chemical_list: D000975:Antioxidants; D007773:Lactates; D019207:beta Carotene; D014527:Uric Acid; D024502:alpha-Tocopherol; D001205:Ascorbic Acid