title: [Studies on the relationship between vitamin D receptor gene polymorphism and osteoporosis in postmenopausal women].
abstract: OBJECTIVE
  To determine the relationship between vitamin D receptor (VDR) gene polymorphism and osteoporosis in postmenopausal women.
  
  
  METHODS
  The polymerase chain reaction-restriction fragment length polymorphism was used to detect VDR genotype in 40 patients with osteoporosis and 21 healthy postmenopausal women.
  
  
  RESULTS
  In the patients with osteoporosis, the bb, Bb, and BB genotype accounted for 82.5%, 17.5% and 0, respectively; in healthy groups, they were 85.71%, 14.29% and 0, respectively (P>0.05).
  
  
  CONCLUSIONS
  Significant association between VDR genotype and osteoporosis in Chinese women was observed in this study.
authors.affiliation: Department of Endocrinology, the Second Teaching Hospital of Chongqing Medical University, Chongqing, 400010 P. R. China. Chen_96938@163.com
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Liping
authors.initials: L
authors.lastname: Zhang
authors.forename: Junfeng
authors.initials: J
authors.lastname: Qiu
authors.forename: Hui
authors.initials: H
authors.lastname: Peng
authors.forename: Zhongliang
authors.initials: Z
authors.lastname: Deng
authors.forename: Yujun
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhongde
authors.initials: Z
authors.lastname: Yan
mesh_terms: D004247:DNA / Q000235:genetics / Q000378:metabolism; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000235:genetics*; D011110:Polymorphism, Genetic; D018167:Receptors, Calcitriol / Q000235:genetics*
chemical_list: D018167:Receptors, Calcitriol; D004247:DNA; C053864:endodeoxyribonuclease BsmI; D015252:Deoxyribonucleases, Type II Site-Specific