[The expression of IL-8 on laryngeal carcinoma and edge tissues].
OBJECTIVE
To explore the expression of IL-8 on laryngeal carcinoma and the edge tissues and its relationship with the character of laryngeal carcinoma.


METHODS
Immunohistochemical SABC detections were carried out in 35 case of original laryngeal cancer and the edge tissues (1.0 cm near the tumor).


RESULTS
The positive rate was 68.6% in 24 case of carcinoma group, 42.9% in 15 case of edge group. The statistical difference between carcinoma group with edge group was very significant(P < 0.05). The expression of IL-8 had no difference in location, tumor developed degree and lymph metastases.


CONCLUSIONS
The expression of IL-8 may play an important role in the process of laryngeal cancer and the patients' immune stage.
Song
Jinhui
J
Department of Otorhinolaryngology, Hospital of PLA 463, Shenyang 110042.
Dai
Song
S
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000378:metabolism*; D005260:Female; D006801:Humans; D016209:Interleukin-8 / Q000096:biosynthesis*; D007822:Laryngeal Neoplasms / Q000276:immunology / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000276:immunology / Q000378:metabolism
D016209:Interleukin-8