title: [Role of IVIG in modern neonatology].
abstract: A newborn presents capacity to respond to specific antigens, but his immune system is still immature. Deficiency of immune function in the neonate is concerned with both innate and acquired immunity and provides to higher morbidity and mortality at this age of life. Therefore many multicentral studies on this field are performed. In the first part of the paper the authors present the development of humoral response and the role of immunoglobulins in infections of fetuses and newborns. The second part contains current views on immunoglobulin therapy in these children.
authors.affiliation: Klinika Neonatologii Akademii Medycznej we Wrocławiu.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Gajewska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Czyzewska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Szafrańska
authors.forename: Monika
authors.initials: M
authors.lastname: Lachowska
mesh_terms: D000917:Antibody Formation / Q000276:immunology; D005315:Fetal Diseases / Q000188:drug therapy / Q000276:immunology; D005333:Fetus / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007231:Infant, Newborn / Q000276:immunology*; D007239:Infections / Q000188:drug therapy* / Q000276:immunology; D009359:Neonatology / Q000379:methods*; D011044:Poland
chemical_list: D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous