title: Central neurocytoma with craniospinal dissemination.
abstract: Central neurocytoma was first described by Hassoun et al. in 1982. The tumor is a rare benign tumor of the central nervous system, usually located in the lateral ventricles. Most reported cases are histologically and clinically benign. Several cases with recurrence have been described. Including the case presented here, only seven cases with craniospinal dissemination have been reported. None of the previous cases with dissemination had histological atypia but most did have a high MIB-1 labeling index (MIB-1 LI). Our patient had a high MIB-1 LI (4.6%) and dissemination was found to have advanced through the anterior horns of the lateral ventricles and to the spinal cord at the T4 level. The patient underwent partial resection of the tumor with follow-up radiation treatments for the residual tumor and dissemination. After the radiation, the size of the tumor decreased. The report of this casewill be helpful in the treatment of disseminated central neurocytoma.
authors.affiliation: Department of Radiology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. takaoh-tky@umin.ac.jp
authors.forename: Hidemasa
authors.initials: H
authors.lastname: Takao
authors.forename: Keiichi
authors.initials: K
authors.lastname: Nakagawa
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
mesh_terms: D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness; D018306:Neurocytoma / Q000473:pathology* / Q000532:radiotherapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*; D013120:Spinal Cord Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D013904:Thoracic Vertebrae / Q000473:pathology