Effects of GSM-900 microwaves on the experimental allergic encephalomyelitis (EAE) rat model of multiple sclerosis.
The effects of acute exposure to GSM-900 microwaves (900 MHz, 217 Hz pulse modulation) on the clinical parameters of the acute experimental allergic encephalomyelitis (EAE) model in rats were investigated in two independent experiments: rats were either habituated or nonhabituated to the exposure restrainers. EAE was induced with a mixture of myelin basic protein and Mycobacterium tuberculosis. Female Lewis rats were divided into cage control, sham exposed, and two groups exposed either at 1.5 or 6.0 W/kg local specific absorption rate (SAR averaged over the brain) using a loop antenna placed over their heads. There was no effect of a 21 day exposure (2 h/day) on the onset, duration, and termination of the EAE crisis.
Anane
R
R
PIOM Laboratory, EPHE, ENSCPB, University of Bordeaux 1, Pessac, France. m.geffard@piom.u-bordeaux.fr
Geffard
M
M
Taxile
M
M
Bodet
D
D
Billaudel
B
B
Dulou
P E
PE
Veyret
B
B
D000818:Animals; D001921:Brain / Q000528:radiation effects*; D040421:Cell Phone; D004195:Disease Models, Animal; D004307:Dose-Response Relationship, Radiation; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D008872:Microwaves; D009103:Multiple Sclerosis / Q000139:chemically induced / Q000503:physiopathology*; D051381:Rats; D011917:Rats, Inbred Lew; D012149:Restraint, Physical / Q000379:methods; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000503:physiopathology