title: Late thrombosis: a problem solved?
abstract: Late thrombosis (angiographic total occlusion associated with an acute coronary syndrome) is a potentially life-threatening complication after intracoronary radiation therapy. This review is intended to explore the preclinical and clinical evidence for late thrombosis, to discuss the etiology, and to provide guidelines for future management. Although we have gained a greater understanding of this complex entity, further research is required in a quest to curtail late thrombosis rates.
authors.affiliation: Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA.
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Ajani
authors.forename: Edouard
authors.initials: E
authors.lastname: Cheneau
authors.forename: Laurent
authors.initials: L
authors.lastname: Leborgne
authors.forename: Roswitha
authors.initials: R
authors.lastname: Wolfram
authors.forename: Ron
authors.initials: R
authors.lastname: Waksman
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology / Q000532:radiotherapy; D023903:Coronary Restenosis / Q000453:epidemiology / Q000517:prevention & control / Q000532:radiotherapy; D019317:Evidence-Based Medicine; D006801:Humans; D011340:Problem Solving; D011878:Radiotherapy / Q000009:adverse effects; D012307:Risk Factors; D013927:Thrombosis / Q000453:epidemiology / Q000209:etiology*; D013997:Time Factors