title: Tuberculosis and badgers: new approaches to diagnosis and control.
abstract: The Eurasian badger (Meles meles) is considered to be an important wildlife reservoir of Mycobacterium bovis infection for cattle in Ireland and in Great Britain. The inability to eradicate the disease from cattle is, in part, a consequence of M. bovis infection in badgers sharing the environment with cattle. Whereas national tuberculosis eradication programmes continue to be effective in maintaining the disease prevalence in cattle at a low level, strategies to control and eradicate tuberculosis in badgers remain constrained by a lack of reagents and rapid tests to diagnose tuberculosis infection in live badgers. However, the development of rational control measures for both badgers and cattle can be achieved by detailed epidemiological analysis combining immunological testing and strain typing with current developments in information technology and geographical information systems. This allows for construction of detailed profiles of tuberculosis episodes which can identify the nature of the outbreak, its likely origin and future spread. The identification of critical areas for control then permits the strategic allocation of resources based on analysis of disease patterns in cattle and badgers. Targeted vaccination of badgers is an option which could facilitate the elimination of disease in affected areas.
authors.affiliation: Large Animal Clinical Studies, Faculty of Veterinary Medicine, University College Dublin, Dublin 4, Ireland. egormley@ucd.ie
authors.forename: E
authors.initials: E
authors.lastname: Gormley
authors.forename: E
authors.initials: E
authors.lastname: Costello
mesh_terms: D000818:Animals; D001500:BCG Vaccine; D002335:Carnivora; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000635:transmission*; D004197:Disease Reservoirs; D006801:Humans; D007494:Ireland; D009163:Mycobacterium bovis / Q000235:genetics; D012698:Serologic Tests / Q000379:methods; D014376:Tuberculosis / Q000175:diagnosis / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D001500:BCG Vaccine