title: Familial urachal sinus associated with a possible congenital malformation: report of a case.
abstract: We report a rare case of familial urachal disease associated with a congenital malformation. A 34-year-old woman was referred to our hospital with recurrent umbilical purulent discharge. She had undergone partial resection of the small intestine for obstruction and, later, a pyeloplasty for a stricture of the ureter-pyelo junction. Her younger brother had also undergone surgery for a urachal sinus 1 year earlier. She was found to have an umbilical granuloma with a fistulous track that could be probed for 3 cm distally. Computed tomography (CT) and ultrasonography confirmed the fistulous track. Under a diagnosis of urachal sinus, a urachal remnant was excised. Histological analysis of the excised specimen revealed only inflammatory granulomatous tissue with marked infiltration of lymphocytes and foreign body giant cells. Urachal cysts are associated with a risk of intestinal strangulation and therefore, the finding of urachal disease justifies detailed evaluation.
authors.affiliation: Department of Gastrointestinal Surgery, The University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kubota
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Nomura
authors.forename: Masaki
authors.initials: M
authors.lastname: Kawahara
authors.forename: Michio
authors.initials: M
authors.lastname: Kaminishi
mesh_terms: D000328:Adult; D005260:Female; D006099:Granuloma / Q000235:genetics; D006801:Humans; D014472:Umbilicus; D014496:Urachal Cyst / Q000235:genetics*; D014497:Urachus / Q000002:abnormalities*