Guidelines and algorithms for the use of methylphenidate in children with Attention-Deficit/ Hyperactivity Disorder.
OBJECTIVE
To review published algorithms for guiding the use of methylphenidate (MPH) in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children and adolescents.


METHODS
A consensus roundtable of 12 experts was convened to review the evidence for the safety and efficacy of MPH in the treatment of ADHD, as well as the published algorithms and practice guidelines for using MPH. The experts reviewed the algorithms for practicality and acceptability by clinicians.


RESULTS
Algorithms that included MPH commonly selected it as the initial medication to be employed in the treatment of children with ADHD. Factors involved included its high efficacy, good safety record, and the ubiquitous nature of its appearance in the ADHD treatment literature.


CONCLUSIONS
MPH should be considered as the first medication to be used in a treatment algorithm for children and adolescents with ADHD.
Greenhill
L
L
New York State Psychiatric Institute/Columbia University, New York 10032, USA. LarryLGreenhill@cs.com
Beyer
D H
DH
Finkleson
J
J
Shaffer
D
D
Biederman
J
J
Conners
C K
CK
Gillberg
C
C
Huss
M
M
Jensen
P
P
Kennedy
J L
JL
Klein
R
R
Rapoport
J
J
Sagvolden
T
T
Spencer
T
T
Swanson
J M
JM
Volkow
N
N
D000293:Adolescent; D000465:Algorithms; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000697:Central Nervous System Stimulants / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D003245:Consensus Statements as Topic; D006801:Humans; D008774:Methylphenidate / Q000009:adverse effects / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
D000697:Central Nervous System Stimulants; D008774:Methylphenidate