9alpha,20-Dihydroxyecdysone, a new natural ecdysteroid from Silene italica ssp. nemoralis.
A new natural compound, 9alpha,20-dihydroxyecdysone (1), and two known related compounds, 20-hydroxyecdysone and ecdysone, were isolated from the herb Silene italica ssp. nemoralis. Compound 1 is the first C-9 hydroxylated ecdysteroid with a cis-fused A/B ring junction to have been isolated from a plant source, and its structure was determined using a combination of spectroscopic techniques.
Pongrácz
Zita
Z
Department of Pharmacognosy, University of Szeged, Szeged, Eötvös utca 6, H-6720, Hungary.
Báthori
Mária
M
Tóth
Gábor
G
Simon
András
A
Mák
Marianna
M
Máthé
Imre
I
D004440:Ecdysone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D006814:Hungary; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D029751:Silene / Q000737:chemistry*; D013237:Stereoisomerism
C476839:9alpha,20-dihydroxyecdysone; D004440:Ecdysone