title: [The effects of n-butanol fraction of Lysimachia hemsleyana on the activities of lymphocytes in mice].
abstract: OBJECTIVE
  To study the effects of n-butanol fraction from the whole plants (Lysimachia hemsleyana) on the phagocytic activities of the peritoneal macrophage, production of interleukin-2.
  
  
  METHODS
  We extracted the components with ethanol, acetic ether, n-butanol and chloroform, then studied the n-butanol fraction on the phagocytic activities of the peritoneal macrophage, production of interleukin-2 (IL-2) from splenocytes induced by ConA in mice in vitro.
  
  
  RESULTS
  n-Butanol fraction of an ethanol extract of air-dried herbs bilaterally regulated the IL-2 production from splenocytes induced by ConA, and enhanced the phagocytic activities of activated mouse peritoneal macrophages.
  
  
  CONCLUSIONS
  The results suggest that Lysimachia hemsleyana may has an immunoregulation effect and may be an potential agent in the treatment of the inflammatory pathological process and some autoimmune diseases.
authors.affiliation: Department of Rheumatology, Changhai Hospital, Second Military Medical University, Shanghai, 200433.
authors.forename: Lanling
authors.initials: L
authors.lastname: Zhang
authors.forename: Jiming
authors.initials: J
authors.lastname: Meng
authors.forename: Haisheng
authors.initials: H
authors.lastname: Chen
authors.forename: Xinghai
authors.initials: X
authors.lastname: Han
mesh_terms: D020001:1-Butanol / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007376:Interleukin-2 / Q000096:biosynthesis; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism; D017737:Macrophages, Peritoneal / Q000276:immunology / Q000378:metabolism; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008813:Mice, Inbred ICR; D010587:Phagocytosis / Q000187:drug effects*; D029623:Primulaceae / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D007376:Interleukin-2; D020001:1-Butanol