Byssochlamysol, a new antitumor steroid against IGF-1-dependent cells from Byssochlamys nivea. II. Physico-chemical properties and structure elucidation.
The structure of byssochlamysol, a new antitumor metabolite against IGF-1-dependent cancer cells from Byssochlamys nivea M#5187, was determined to be a highly oxidized ergostane steroid as shown in Fig. 1 by NMR studies.
Mori
Toshiya
T
Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
Shin-ya
Kazuo
K
Takatori
Kosuke
K
Aihara
Maki
M
Hayakawa
Yoichi
Y
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D032641:Eurotiales / Q000737:chemistry*; D007334:Insulin-Like Growth Factor I / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D000970:Antineoplastic Agents; D013256:Steroids; C472758:byssochlamysol; D007334:Insulin-Like Growth Factor I