Steroid myopathy in a child with juvenile rheumatoid arthritis. Case report.
An 8-year-old boy who had been diagnosed as systemic-onset juvenile rheumatoid arthritis were on treatment for 8 months with methotrexate and additional steroids during activation. At the end of the 8th month when the corticosteroid dose was 12.5 mg/day, he began to suffer from numbness and weakness in his hands. Physical examination, laboratory findings and electromyography results demonstrated myopathy. Steroid myopathy was considered. Corticosteroids were tapered and stopped. At follow-up clinical findings remitted and electromyography became normal at the 4th month. We present here this case to direct attention to drug-induced myopathy besides myopathy due to primary disease in connective tissue disorders whenever myopathy exists.
Genel
F
F
Department of Pediatrics and Pathology, Dr. Behçet Uz Children's Hospital, Izmir, Turkey. ferahgen@yahoo.com
Arslanoglu
S
S
Hizarcioglu
M
M
Durmaz
B
B
Uran
N
N
Aktaş
S
S
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects*; D009135:Muscular Diseases / Q000139:chemically induced* / Q000473:pathology
D000305:Adrenal Cortex Hormones; D018501:Antirheumatic Agents; D008727:Methotrexate