Comparative biology of gamma delta T cells.
Accumulative evidence suggests that resident gamma delta T cells in epithelia are biologically distinct from systemic gamma delta T cells in the circulation. Murine resident gamma delta T cells have innate immune characteristics and play an important role in tissue homeostasis after damages. In contrast, a unique subset of circulating gamma delta T cells in primates, like alpha beta T cells, can mount adaptive immune responses in infections. This article compares biological features between resident and circulating gamma delta T cells.
Chen
Zheng W
ZW
zchen@caregroup.harvard.edu
D000818:Animals; D004848:Epithelium / Q000276:immunology; D006801:Humans; D007156:Immunologic Memory; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D016692:Receptors, Antigen, T-Cell, gamma-delta