title: Familial eccrine spiradenoma: a case report and review of the literature.
abstract: BACKGROUND
  Familial eccrine spiradenoma is a rare autosomal dominant condition that is characterized by slow-growing, benign adnexal tumors.
  
  
  OBJECTIVE
  We investigated a case of familial eccrine spiradenoma displaying an autosomal dominant inheritance pattern. To our knowledge, only two previously reported cases of familial eccrine spiradenoma exist in the literature.
  
  
  METHODS
  A case report and review of the literature are given.
  
  
  RESULTS
  We report a case of familial eccrine spiradenoma in a mother and daughter and present successful treatment using surgical extirpation and CO2 laser ablation.
  
  
  CONCLUSIONS
  Familial eccrine spiradenoma is a benign autosomal dominantly inherited condition that is characterized by tender, slow-growing, adnexal tumors of the head and neck. Surgical tumor extirpation and CO2 laser ablation offer both an effective symptomatic and cosmetically elegant treatment option.
authors.affiliation: Department of Dermatology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Maryanna C
authors.initials: MC
authors.lastname: Ter Poorten
authors.forename: Kate
authors.initials: K
authors.lastname: Barrett
authors.forename: Joel
authors.initials: J
authors.lastname: Cook
mesh_terms: D006607:Adenoma, Sweat Gland / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D013544:Sweat Gland Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery