Amniotic band syndrome with significant orofacial clefts and disruptions and distortions of craniofacial structures.
Amniotic band syndrome (ABS) is a rare disorder in which bands of mesoderm that emanate from the chorionic side of the amnion and insert on the fetal body can generate a wide variety of disfiguring and disabling malformations. It usually is sporadic, and the incidence is approximately 1 in 15,000 live births, and affected children typically require involvement of several pediatric surgical subspecialties. The authors describe a case of ABS with extensive craniofacial anomalies.
Muraskas
Jonathan K
JK
Division of Neonatal-Perinatal Medicine, Pediatric Ophthalmology, and Pediatric Surgery, Ronald McDonald Children's Hospital, Loyola University Medical Center, Maywood, Illinois, USA.
McDonnell
James F
JF
Chudik
Ronald J
RJ
Salyer
Kenneth E
KE
Glynn
Loretto
L
D000015:Abnormalities, Multiple; D000328:Adult; D000652:Amniotic Band Syndrome; D015858:Anisometropia / Q000209:etiology; D002971:Cleft Lip / Q000601:surgery; D005124:Eye Abnormalities / Q000601:surgery; D005143:Eyelids / Q000002:abnormalities; D005145:Face / Q000002:abnormalities*; D005260:Female; D005315:Fetal Diseases / Q000821:virology; D006801:Humans; D007231:Infant, Newborn; D009915:Orbit / Q000002:abnormalities*; D010322:Parvoviridae Infections / Q000196:embryology; D016732:Parvovirus B19, Human; D011247:Pregnancy; D013701:Temporal Bone / Q000002:abnormalities