A case series of ziprasidone overdoses.
In recent years, prescriptions for atypical antipsychotic medications have surpassed traditional antipsychotic agents because of improved treatment of the negative symptoms associated with schizophrenia and a relatively safer side effect profile. The relatively new atypical antipsychotic agent ziprasidone has become a popular treatment for schizophrenia, and like other psychiatric medications has potential for misuse. This series reports 3 cases of ziprasidone overdose. Diligence in cardiac monitoring and obtaining a history of possible co-ingestion are vital in the management of these patients.
Bryant
Sean M
SM
Toxikon Consortium/Cook County Hospital, Section of Toxicology, Suite 500, 1900 West Polk Street, Chicago, IL 60612, USA.
Zilberstein
Jeff
J
Cumpston
Kirk L
KL
Magdziarz
Dan D
DD
Costerisan
Dennis D
DD
D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000506:poisoning*; D003937:Diagnosis, Differential; D062787:Drug Overdose / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010879:Piperazines / Q000506:poisoning*; D013844:Thiazoles / Q000506:poisoning*
D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone