Study of solubility of isoproturon by its complexation with beta-cyclodextrin.
The inclusion complexes of beta-cyclodextrin-isoproturon were prepared using techniques such as kneading, co-evaporation, and co-precipitation. These complexes were characterised for physical properties and spectral studies such as UV, FTIR, and 1HNMR spectroscopy. To investigate the stoichiometry of the complexes Phase solubility method was adopted. Most of the complexes showed an increase in the dissolution rate of the herbicide. The best results were obtained when inclusion complexes were prepared by co-precipitation and co-evaporation method. Findings of this paper will allow the rational use of isoproturon with increase in its efficacy.
Manolikar
M K
MK
Applied Chemistry Division, Institute of Chemical Technology, University of Mumbai, Matunga, 400 019, Mumbai, India.
Sawant
M R
MR
D002273:Carcinogens / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D006540:Herbicides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008782:Methylurea Compounds / Q000737:chemistry*; D010671:Phenylurea Compounds; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D047392:beta-Cyclodextrins
D002273:Carcinogens; D003505:Cyclodextrins; D006540:Herbicides; D008782:Methylurea Compounds; D010671:Phenylurea Compounds; D047392:beta-Cyclodextrins; C028904:isoproturon; C031215:betadex