Phylogenetic analysis of Vietnamese isolates of feline immunodeficiency virus: genetic diversity of subtype C.
Phylogenetic relationships of novel Vietnamese strains of feline immunodeficiency virus (FIV) were analysed. One Vietnamese strain was found to cluster with subtype D, which was previously known only in Japan, while the other seven strains were placed with members of subtype C. Calculation of the relative numbers of mutations resulting in amino acid and silent changes in FIV env subtypes suggested that subtype C isolates may be less structurally constrained (potentially more pathogenic) than subtype B.
Nakamura
K
K
Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Suzuki
Y
Y
Ikeo
K
K
Ikeda
Y
Y
Sato
E
E
Nguyen
N T P
NT
Gojobori
T
T
Mikami
T
T
Miyazawa
T
T
D000818:Animals; D002415:Cats / Q000821:virology*; D002460:Cell Line; D014644:Genetic Variation; D016089:Immunodeficiency Virus, Feline / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D007963:Leukocytes, Mononuclear / Q000821:virology; D008969:Molecular Sequence Data; D009154:Mutation; D010802:Phylogeny; D014744:Vietnam; D014759:Viral Envelope Proteins / Q000235:genetics
D014759:Viral Envelope Proteins