title: Chemically regulated gene expression in plants.
abstract: Chemically inducible systems that activate or inactivate gene expression have many potential applications in the determination of gene function and in plant biotechnology. The precise timing and control of gene expression are important aspects of chemically inducible systems. Several systems have been developed and used to analyze gene function, marker-free plant transformation, site-specific DNA excision, activation tagging, conditional genetic complementation, and restoration of male fertility. Chemicals that are used to regulate transgene expression include the antibiotic tetracycline, the steroids dexamethasone and estradiol, copper, ethanol, the inducer of pathogen-related proteins benzothiadiazol, herbicide safeners, and the insecticide methoxyfenozide. Systems that are suitable for field application are particularly useful for experimental systems and have potential applications in biotechnology.
authors.affiliation: RHeoGene/Rohm and Haas, PO Box 949, Spring House, Pennsylvania 19477-0949, USA.
authors.forename: Malla
authors.initials: M
authors.lastname: Padidam
mesh_terms: D003300:Copper / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology; D018506:Gene Expression Regulation, Plant / Q000187:drug effects*; D005818:Genetic Engineering / Q000379:methods*; D006728:Hormones / Q000494:pharmacology; D030821:Plants, Genetically Modified; D012097:Repressor Proteins / Q000378:metabolism; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D006728:Hormones; D012097:Repressor Proteins; D000431:Ethanol; D003300:Copper; D013752:Tetracycline