title: Catheter cryoablation of supraventricular arrhythmias: a painless alternative to radiofrequency energy.
abstract: Cryothermy has potential advantages over RF energy for catheter ablation, including reversibility of lesion formation, catheter stability, and less procedural discomfort. Cryoablation procedures were performed in 14 patients with atrioventricular reentrant tachycardias (AVNRTs), 13 patients with accessory pathway (AP)-mediated tachycardias, and 5 patients with atrial fibrillation. The numbers of energy applications, pain scores, procedural times, and outcomes were recorded and compared with age- and sex-matched patients undergoing similar RF procedures. Cryoablation was successful in 26 of 32 patients (11/14 AVNRT, 10/13 AP, 5/5 AF) compared with 30 of 32 undergoing RF procedures, with similar numbers of energy applications and procedural times. Cryothermy was painless in all patients, and the overall procedural discomfort was significantly less than in patients treated with RF (1.3 +/- 2.2 vs 6.1 +/- 3.5). In patients with anteroseptal pathways, cryomapping successfully identified safe sites to target the delivery of energy. Cryothermy is a painless and safe alternative to RF. It may be particularly useful for catheter ablation of patients with pathways close to the atrioventricular node.
authors.affiliation: Cardiac Electrophysiology Unit, Papworth Hospital, Cambridge CB3 8RE, UK.
authors.forename: Martin D
authors.initials: MD
authors.lastname: Lowe
authors.forename: Maggie
authors.initials: M
authors.lastname: Meara
authors.forename: James
authors.initials: J
authors.lastname: Mason
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Grace
authors.forename: Francis D
authors.initials: FD
authors.lastname: Murgatroyd
mesh_terms: D000328:Adult; D001281:Atrial Fibrillation / Q000628:therapy; D017115:Catheter Ablation / Q000009:adverse effects; D003452:Cryosurgery / Q000009:adverse effects; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000601:surgery; D006801:Humans; D008297:Male; D010147:Pain Measurement; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000601:surgery; D013617:Tachycardia, Supraventricular / Q000601:surgery*