Neuropathological findings in Sneddon's syndrome.
The authors report the neuropathologic findings in a case of Sneddon's syndrome. There were multiple small, predominantly cortical, infarcts, with focal hyperplasia and fibrotic occlusion of arterial vessels in the superficial white matter, cortex, and leptomeninges. A very occasional arterial thrombus was seen. These findings suggest that Sneddon's syndrome is caused by a noninflammatory arteriopathy affecting superficial cerebral vessels.
Hilton
David A
DA
Department of Histopathology, Derriford Hospital, Plymouth, UK. david.hilton@phnt.swest.nhs.uk
Footitt
David
D
D001160:Arterioles / Q000473:pathology; D001921:Brain / Q000098:blood supply / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology; D002544:Cerebral Infarction / Q000209:etiology / Q000473:pathology; D003328:Coronary Thrombosis / Q000150:complications / Q000473:pathology; D016757:Death, Sudden, Cardiac; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D017445:Skin Diseases, Vascular / Q000175:diagnosis* / Q000209:etiology; D018860:Sneddon Syndrome / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology