New chemical synthesis of functionalized arylzinc compounds from aromatic or thienyl bromides under mild conditions using a simple cobalt catalyst and zinc dust.
A new chemical method for the preparation of arylzinc intermediates is described in acetonitrile, on the basis of the activation of aryl bromides by low-valent cobalt species arising from the reduction of cobalt halide by zinc dust. This procedure allows for the synthesis of a variety of functionalized aryl- and thienylzinc species in good to excellent yields. The versatility and the simplicity of that original method represent an alternative to most known procedures.
Fillon
Hyacinthe
H
Laboratoire d'Electrochimie, Catalyze et Synthèse Organique, UMR 7582 CNRS-Université Paris 12 2, rue Henry-Dunant 94320 Thiais, France.
Gosmini
Corinne
C
Périchon
Jacques
J