title: [Comparative study of two Tramadol prescription protocols for postoperative analgesia in children].
abstract: We reported the result of a prospective study concerning the use of Tramadol for postoperative analgesia in children. Seventy-two children 1 to 6 year's old were enrolled. Tramadol was given at a dose of 1 mg/kg for 30 minutes and Oral regimen started 4 hours after at a dose of 0.5 mg/kg/6 hours for 24 hours in 40 child. Only one dose of Tramadôl, 2 Mg/kg, was used in other 32 children. We assessed every 3 hours: pain scale (CHEOPS), respiratory rate, and cardiac rate, blood pressure and sedation scale. We obtained satisfactory analgesia in 70% of children since the first hour postoperatively with 2 mg/kg Tramadol and in 60% of them who received 1 mg/kg. In the first group, analgesia had lasted for 24 hours in 62.5% of children and in 80% of children with oral Tramadol. The main side effect was vomiting as reported in 25% of children especially after intravenous Tramadol and mild sedation in 34% of them. Tramadol is a safe and efficient analgesic molecule in children.
authors.affiliation: Service d'orthopédie infantile, Hôpital d'enfants de Tunis, Tunisie.
authors.forename: Olfa
authors.initials: O
authors.lastname: Kaabachi
authors.forename: Hayet
authors.initials: H
authors.lastname: el Jaouani
authors.forename: Hathem
authors.initials: H
authors.lastname: Safi
authors.forename: Chakib
authors.initials: C
authors.lastname: Jelel
authors.forename: Maher
authors.initials: M
authors.lastname: Ben Ghachem
mesh_terms: D000284:Administration, Oral; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D002985:Clinical Protocols; D016903:Drug Monitoring; D011307:Drug Prescriptions; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy*; D011446:Prospective Studies; D012119:Respiration / Q000187:drug effects; D013997:Time Factors; D014147:Tramadol / Q000008:administration & dosage* / Q000494:pharmacology; D016896:Treatment Outcome; D014839:Vomiting / Q000139:chemically induced
chemical_list: D000701:Analgesics, Opioid; D014147:Tramadol