title: Dilated cardiomyopathy in a 3-year-old girl with a terminal deletion, 46,XX,del(3)(q27-qter), of the long arm of chromosome 3.
abstract: We report a case in which a 3-year-old girl with terminal deletion of the long arm of chromosome 3 had dilated cardiomyopathy, a complication that has not previously been reported in association with this chromosome abnormality. In addition to cardiomyopathy, she had intrauterine growth retardation, small eyes and mouth, a broad nose, thin lips, low-set ears, a short neck and overlapping second toes.
  
  
  CONCLUSIONS
  due to the paucity of reported cases of 3q deletion, and the clinical variability of such cases, identification of a distinct 3q phenotype (including cardiac complications) remains elusive.
authors.affiliation: Department of Paediatric Cardiology, Saitama Heart Institute, Saitama Medical School Hospital, 38 Morohongo, Moroyama, Japan. hsenzaki@saitama-med.ac.jp
authors.forename: Hideaki
authors.initials: H
authors.lastname: Senzaki
authors.forename: Mika
authors.initials: M
authors.lastname: Inui
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Ban
authors.forename: Satoshi
authors.initials: S
authors.lastname: Masutani
authors.forename: Mofeed
authors.initials: M
authors.lastname: Morsy
authors.forename: Toshiki
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Hironori
authors.initials: H
authors.lastname: Nagasaka
authors.forename: Nozomu
authors.initials: N
authors.lastname: Sasaki
authors.forename: Shunei
authors.initials: S
authors.lastname: Kyo
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yokote
mesh_terms: D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D002675:Child, Preschool; D002872:Chromosome Deletion; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D017809:Fatal Outcome; D005260:Female; D006801:Humans