title: [Incidence some congenital defects in Monterrey, Mexico].
abstract: OBJECTIVE
  In Mexico, the congenital defects (CD) in newborns represent the third cause of infant morbi-mortality. Incidence rates/1000 reported for our country vary from 8.15 (Puebla) to 32.90 (Distrito Federal). The aim of this study was to estimate the incidence of some CD in Monterrey, Mexico.
  
  
  METHODS
  A transversal, prospective, descriptive, and observational study was carried out at the Hospital de Ginecologia y Obstetricia No. 23, IMSS during January 1995 to December 1999. The external CD were analyzed according to World Health Organization (WHO) and classified according to their topography distribution.
  
  
  RESULTS
  A total incidence of 9.89 [(1309/132,369)* 1000)] was detected. The more frequent CD were: the nervous system (2.33), the chromosomal (1.67), osteomuscular (1.67) of face and neck (1.18), and reproductive system (0.81). The less frequent CD were: the digestive system (0.43), diverse syndromes (0.38), and skin (0.29).
  
  
  CONCLUSIONS
  Even though the global incidence of DC observed in this study is into the rank informed in the national and international literature. Because of this incidence has a great variability, we considered important to homogenize diagnosis criteria for each DC. With this results it will be possible to carry out comparative cross-sectional studies to determine if they are similar or different and then, by association studies to establish its possible etiological factors.
authors.affiliation: Departamento de Genética, Hospital de Ginecología y Obstetricia No. 23 Dr. Ignacio Morones Prieto, Instituto Mexicano del Seguro Social IMSS.
authors.forename: Ricardo J
authors.initials: RJ
authors.lastname: Hernández-Herrera
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Cerda-Flores
authors.forename: Martha I
authors.initials: MI
authors.lastname: Dávila-Rodríguez
authors.forename: Elva I
authors.initials: EI
authors.lastname: Cortés-Gutiérrez
mesh_terms: D000013:Congenital Abnormalities / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D008800:Mexico / Q000453:epidemiology; D011446:Prospective Studies