title: Steroid myopathy in a child with juvenile rheumatoid arthritis. Case report.
abstract: An 8-year-old boy who had been diagnosed as systemic-onset juvenile rheumatoid arthritis were on treatment for 8 months with methotrexate and additional steroids during activation. At the end of the 8th month when the corticosteroid dose was 12.5 mg/day, he began to suffer from numbness and weakness in his hands. Physical examination, laboratory findings and electromyography results demonstrated myopathy. Steroid myopathy was considered. Corticosteroids were tapered and stopped. At follow-up clinical findings remitted and electromyography became normal at the 4th month. We present here this case to direct attention to drug-induced myopathy besides myopathy due to primary disease in connective tissue disorders whenever myopathy exists.
authors.affiliation: Department of Pediatrics and Pathology, Dr. Behçet Uz Children's Hospital, Izmir, Turkey. ferahgen@yahoo.com
authors.forename: F
authors.initials: F
authors.lastname: Genel
authors.forename: S
authors.initials: S
authors.lastname: Arslanoglu
authors.forename: M
authors.initials: M
authors.lastname: Hizarcioglu
authors.forename: B
authors.initials: B
authors.lastname: Durmaz
authors.forename: N
authors.initials: N
authors.lastname: Uran
authors.forename: S
authors.initials: S
authors.lastname: Aktaş
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects*; D009135:Muscular Diseases / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D018501:Antirheumatic Agents; D008727:Methotrexate