Chemical chaperones--a new concept in drug research.
Kolter
Thomas
T
Kekulé-Institut für Organische Chemie und Biochemie der Universität Gerhard-Domagk Strasse 1, 53121 Bonn, Germany. tkolter@uni-bonn.de
Wendeler
Michaela
M
D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives; D000818:Animals; D004795:Enzyme Stability / Q000187:drug effects; D000795:Fabry Disease / Q000188:drug therapy* / Q000378:metabolism; D005690:Galactose / Q000737:chemistry / Q000494:pharmacology; D005776:Gaucher Disease / Q000188:drug therapy* / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D006801:Humans; D050111:Imino Sugars; D008970:Molecular Weight; D010880:Piperidines / Q000737:chemistry / Q000494:pharmacology; D011487:Protein Conformation / Q000187:drug effects*; D017510:Protein Folding; D000519:alpha-Galactosidase / Q000037:antagonists & inhibitors / Q000235:genetics
D050111:Imino Sugars; D010880:Piperidines; D017485:1-Deoxynojirimycin; C090092:migalastat; D006026:Glycoside Hydrolases; D000519:alpha-Galactosidase; D005690:Galactose