title: Transient cerebral arteriopathy in infancy associated with enteroviral infection.
abstract: We report the case of an 18-month-old boy who presented aphasia and right hemiplegia of acute onset. The neurological deficit completely resolved after a few hours, but identical transient neurological deficits and seizures occurred during the following days. Imaging showed proximal stenosis of the medial cerebral artery and deep ischaemic lesions in the territory of this artery. Analysis of the cerebrospinal fluid showed pleocytosis and an active enteroviral infection with positive RNA detection. The evolution was consistent with transient cerebral arteriopathy of childhood as magnetic resonance angiography showed normalization of the arterial lesions. This is the first report of an enteroviral infection associated with this entity. We want to stress the importance of performing a cerebrospinal fluid analysis when an ischaemic stroke of unclear aetiology occurs in a child.
authors.affiliation: Department of Paediatric Neurology, Université Libre de Bruxelles, Hôpital Erasme, Belgium.
authors.forename: Pascale
authors.initials: P
authors.lastname: Ribai
authors.forename: Corinne
authors.initials: C
authors.lastname: Liesnard
authors.forename: Georges
authors.initials: G
authors.lastname: Rodesch
authors.forename: Sanda
authors.initials: S
authors.lastname: Giurgea
authors.forename: Denis
authors.initials: D
authors.lastname: Verheulpen
authors.forename: Philippe
authors.initials: P
authors.lastname: David
authors.forename: Patrick
authors.initials: P
authors.lastname: Van Bogaert
mesh_terms: D003251:Constriction, Pathologic; D004769:Enterovirus Infections / Q000134:cerebrospinal fluid / Q000150:complications*; D006801:Humans; D007223:Infant; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000821:virology*; D018810:Magnetic Resonance Angiography; D008297:Male; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000473:pathology*; D016133:Polymerase Chain Reaction; D011859:Radiography; D012075:Remission, Spontaneous; D012640:Seizures / Q000134:cerebrospinal fluid / Q000821:virology*