title: Risk of cesarean section in singleton pregnancies after assisted reproductive techniques.
abstract: OBJECTIVE
  To evaluate the perinatal outcome of singleton pregnancies after assisted reproductive techniques in comparison with that in matched controls from spontaneous pregnancies.
  
  
  METHODS
  A total of 11,776 deliveries from January 1, 1995, to May 31, 2001, were subjected to retrospective analysis. Data on 259 neonates from singleton pregnancies after ovulation induction (n = 85, 32.8%), intrauterine insemination (n = 17, 6.6%) or in vitro fertilization (n = 157, 60.6%) were evaluated. The pregnancy outcome was compared with that for controls (n = 518) matched for age, gravidity and parity after spontaneous pregnancies.
  
  
  RESULTS
  Cesarean section was significantly more frequent in the study group than in the control group (42.1% vs. 27.6%, P < .001, odds ratio [OR] 1.91, 95% confidence interval [CI] 1.39-2.61). The prevalence of preterm deliveries was not significantly higher (P = .40, OR 1.23, 95% CI .78-1.95) in the study group as compared with the controls (12.7% vs. 10.6%). There was no significant difference in intrauterine growth retardation between the two groups (9.3% vs. 6.2%, P = .14, OR 1.55, 95% CI .89-2.69).
  
  
  CONCLUSIONS
  Singleton pregnancies after assisted reproductive techniques are associated with an increased rate of cesarean section, whereas neonatal outcome is not influenced.
authors.affiliation: Department of Obstetrics and Gynecology, University of Szeged, Center for Assisted Reproduction, Kaáli Institute, Department of Pediatrics, University of Szeged, Szeged, Hungary.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Kozinszky
authors.forename: Janos
authors.initials: J
authors.lastname: Zádori
authors.forename: Hajnalka
authors.initials: H
authors.lastname: Orvos
authors.forename: Márta
authors.initials: M
authors.lastname: Katona
authors.forename: Attila
authors.initials: A
authors.lastname: Pál
authors.forename: László
authors.initials: L
authors.lastname: Kovács
mesh_terms: D000328:Adult; D002585:Cesarean Section; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007315:Insemination, Artificial / Q000009:adverse effects*; D008297:Male; D007744:Obstetric Labor Complications / Q000209:etiology*; D010062:Ovulation Induction / Q000009:adverse effects*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011256:Pregnancy Outcome; D017584:Reproductive History; D012189:Retrospective Studies; D018570:Risk Assessment