[HPV 16 DNA occurrence in lymph nodes of patients with cervical carcinoma].
OBJECTIVE
We estimated the occurrence of DNA HPV 16 presence in lymph nodes of 25 patients undergoing abdominal operation for cervical carcinoma.


METHODS
The presence of HPV 16 DNA was detected during the preoperative diagnosis procedure by the PCR method.


RESULTS
According to the histopathological examination, metastases in the lymph nodes were present in material from two patients. It was confirmed HPV 16 DNA was detected with PCP. We found also 6 patients with HPV 16 DNA in their lymph nodes without histological confirmation.


CONCLUSIONS
We consider PCR detection of HPV DNA as a simple and useful support of pathology diagnosis.
Łukaszuk
Krzysztof
K
Samodzielnej Pracowni Endokrynologii i Diagnostyki Laboratoryjnej, Gdańsku.
Liss
Joanna
J
Gulczyński
Jacek
J
Woźniak
Izabela
I
Emerich
Janusz
J
Wójcikowski
Czesław
C
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D002277:Carcinoma / Q000473:pathology / Q000601:surgery / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000821:virology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications* / Q000821:virology; D016133:Polymerase Chain Reaction; D013997:Time Factors; D014412:Tumor Virus Infections / Q000150:complications* / Q000821:virology; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery / Q000821:virology*
D000914:Antibodies, Viral; D004279:DNA, Viral
Wystepowanie DNA wirusa HPV 16 w przerzutach do wezłówa chłonnych u chorych na raka szyjki macicy.