title: Clinical outcomes of coronary revascularization without cardiopulmonary bypass.
abstract: OBJECTIVE
  Coronary artery bypass without cardiopulmonary bypass (OPCAB) eliminates the complications related to cardiopulmonary bypass. However, the long-term outcomes of this procedure are largely unknown.
  
  
  METHODS
  We sought to investigate the rates of late mortality, stroke, acute myocardial infarction, and target vessel reintervention after OPCAB in a consecutive series of 857 patients who underwent OPCAB between May 1987 and March 1999.
  
  
  RESULTS
  Long-term follow-up was obtained for 86% of eligible patients. Actuarial and event-free survival was 89% and 76%, respectively, for a median follow-up period of 2.2 years (range, 0-13.3 years). Risk factors for late mortality were identified with Cox regression analysis. In the multivariate analysis, patient age >75 years (odds ratio, 1.1; 95% confidence interval, 1.0-1.1; P =.01) and an ejection fraction <35% (odds ratio, 2.7; 95% confidence interval, 1.2-6.2; P =.02) emerged as independent predictors of late mortality.
  
  
  CONCLUSIONS
  OPCAB is associated with a low mortality and clinical event rate. Advanced age and depressed ejection fraction may increase mortality after OPCAB.
authors.affiliation: Section of Cardiac Surgery, Georgetown University Hospital, Washington, DC, USA.
authors.forename: Sotiris C
authors.initials: SC
authors.lastname: Stamou
authors.forename: Albert J
authors.initials: AJ
authors.lastname: Pfister
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Jablonski
authors.forename: Peter C
authors.initials: PC
authors.lastname: Hill
authors.forename: Mercedes K C
authors.initials: MK
authors.lastname: Dullum
authors.forename: Ammar S
authors.initials: AS
authors.lastname: Bafi
authors.forename: Steven W
authors.initials: SW
authors.lastname: Boyce
authors.forename: Jorge M
authors.initials: JM
authors.lastname: Garcia
authors.forename: Tracie A
authors.initials: TA
authors.lastname: Lomax
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Corso
mesh_terms: D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D001281:Atrial Fibrillation / Q000209:etiology; D002315:Cardiopulmonary Bypass; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D013318:Stroke Volume; D016019:Survival Analysis; D016896:Treatment Outcome