title: Allergic contact dermatitis from occupational exposure to ranitidine hydrochloride.
abstract: Contact sensitivity to ranitidine hydrochloride has been demonstrated in 6 of 8 symptomatic exposed pharmaceutical manufacturing employees; a 7th has been found to be sensitized to ranitidine base. Although closed manufacturing processes diminish the risk of such sensitization, operatives with potential exposure should be made aware of the importance of avoiding skin contact.
authors.affiliation: Employee Health Management, GlaxoSmithKline, Brentford, Middlesex, UK.
authors.forename: P J J
authors.initials: PJ
authors.lastname: Ryan
authors.forename: R J G
authors.initials: RJ
authors.lastname: Rycroft
authors.forename: I R
authors.initials: IR
authors.lastname: Aston
mesh_terms: D000328:Adult; D002617:Chemical Industry; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D010328:Patch Tests; D011899:Ranitidine / Q000009:adverse effects*; D018570:Risk Assessment; D012494:Sampling Studies; D012680:Sensitivity and Specificity
chemical_list: D011899:Ranitidine