title: Surgical ablation of retinal angiomatous proliferation.
abstract: Age-related macular degeneration (AMD) remains the leading cause of visual loss in adults older than 65 years. Retinal angiomatous proliferation (RAP) is a newly recognized manifestation of exudative AMD that has a poor natural history and demonstrated resistance to treatment with conventional laser photocoagulation. A novel surgical technique has been developed in this pilot series that shows promise in the treatment of this subtype of neovascular lesions. Through specific surgical lysis of the feeding arteriole and draining venule of an RAP lesion, improvement in visual acuity has been noted. This has been correlated with resolution of intraretinal edema and flattening of associated pigment epithelial detachment, which was confirmed by fluorescein angiography, optical coherence tomography, and high-speed indocyanine green angiography.
authors.affiliation: Retina Service, Wills Eye Hospital, Philadelphia, PA 19107, USA.
authors.forename: J Luigi
authors.initials: JL
authors.lastname: Borrillo
authors.forename: Arunan
authors.initials: A
authors.lastname: Sivalingam
authors.forename: Adam
authors.initials: A
authors.lastname: Martidis
authors.forename: Jay L
authors.initials: JL
authors.lastname: Federman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D007368:Interferometry; D008027:Light; D008268:Macular Degeneration / Q000150:complications / Q000601:surgery; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012171:Retinal Vessels / Q000473:pathology / Q000601:surgery*; D014054:Tomography; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green