Mechanical properties and in vitro degradation of bioabsorbable self-expanding braided stents.
The aim of this study was to characterize the mechanical and self-expansion properties of braided bioabsorbable stents. In total four different stents were manufactured from PLLA fibres using a braiding technique. The changes in radial pressure stiffness and diameter recovery of the stents were determined initially, and after insertion and release from a delivery device. The braided stents were compared to three commercially available metallic braided stents. The changes in physical and mechanical properties of the PLLA fibres and stents during in vitro degradation were investigated. After release from the delivery device, the PLLA stents did not fully recover to their original diameter. The radial pressure stiffness of the bioabsorbable stents was similar to that of the metallic stents. The in vitro degradation study showed that the stents would keep at least half of their initial radial pressure stiffness for more than 22 weeks.
Nuutinen
Juha-Pekka
JP
Institute of Biomaterials, Tampere University of Technology, PO Box 589, FIN-33101 Tampere, Finland.
Clerc
Claude
C
Reinikainen
Raija
R
Törmälä
Pertti
P
D001673:Biodegradation, Environmental; D004548:Elasticity; D004867:Equipment Design; D011091:Polyesters / Q000737:chemistry* / Q000493:pharmacokinetics; D015607:Stents; D014783:Viscosity
D011091:Polyesters; C033616:poly(lactide)