Prophylactic use of clobazam in hot water epilepsy.
OBJECTIVE
To assess the efficacy of intermittent administration of clobazam to prevent hot water epilepsy.


METHODS
Ten adults with 1:1 ratio of hot water epilepsy were administered 10 mg of clobazam about one and half hour before each hot water head bath. They were followed up for nine months.


RESULTS
Nine out of 10 patients did not develop recurrence of seizure following regular hot water head bath during nine month follow up period. One continued to get mild giddiness. The adverse effects observed were sleepiness in two and fall in memory in one on the day of drug intake.


CONCLUSIONS
Intermittent oral administration of clobazam before hot water bath alone is effective in preventing hot water epilepsy with 1:1 ratio.
Dhanaraj
M
M
Department of Neurology, Government Stanley Medical College and Hospital, Chennai-600 001.
Jayavelu
A
A
D000328:Adult; D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D001569:Benzodiazepines; D002648:Child; D000078306:Clobazam; D020195:Epilepsy, Reflex / Q000209:etiology / Q000517:prevention & control*; D006801:Humans
D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D001569:Benzodiazepines; D000078306:Clobazam