title: Foveal thickness in occult macular dystrophy.
abstract: OBJECTIVE
  Occult macular dystrophy (OMD) is an inherited macular dystrophy characterized by a progressive macular dysfunction without any visible fundus abnormality. We studied the foveal thickness in patients with OMD using optical coherence tomography (OCT).
  
  
  METHODS
  Observational case series. Foveal thickness by OCT images.
  
  
  METHODS
  Foveal thickness obtained from 22 eyes of 11 patients with OMD was compared with that from 27 eyes of 20 age-matched normal controls.
  
  
  RESULTS
  Mean foveal thickness in the patients group (96.5 +/- 19.5 microm) was significantly thinner than that in the normal controls (133.3 +/- 9.0 microm, P <.0001, Mann-Whitney U test). Eighteen of 22 eyes with OMD had foveal thickness that were thinner than the lower limit of the normal range. There was no statistically significant correlation between the foveal thickness and visual acuity, age, or duration from onset.
  
  
  CONCLUSIONS
  These results demonstrated that there are significant anatomic changes in the macula of patients with OMD.
authors.affiliation: Department of Ophthalmology, Nagoya University School of Medicine, Japan. kondomi@med.nagoya-u.ac.jp
authors.forename: Mineo
authors.initials: M
authors.lastname: Kondo
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Ito
authors.forename: Shinji
authors.initials: S
authors.lastname: Ueno
authors.forename: Chang-Hua
authors.initials: CH
authors.lastname: Piao
authors.forename: Hiroko
authors.initials: H
authors.lastname: Terasaki
authors.forename: Yozo
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000293:Adolescent; D000328:Adult; D003941:Diagnostic Techniques, Ophthalmological; D004596:Electroretinography; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D007368:Interferometry; D008027:Light; D008268:Macular Degeneration / Q000175:diagnosis*; D008875:Middle Aged; D014054:Tomography / Q000379:methods; D014792:Visual Acuity