[Effect of zinc on the growth of cerebral cortex neurons of human fetus].
With the primary cultured cerebral cortex neurons of human fetus, studies were made to investigate the effect of zinc on the growth of neurons by using immunohistochemical stain and image analysis. The main results were as follows: (1) The growth of neurons of zinc group was the most prosperous at the 10-14 day of primary culture. The number of survival neurons was increased at the 1-28 day of culture (P < 0.01). (2) In the presence of zinc, the number and the length of neurites as well as the soma areas were all increased remarkably(P < 0.01). It was concluded that zinc could promote the growth of neurons.
Cong
L
L
Department of Nutrition of Qingdao Medical College, Qingdao 266021, China.
Wang
Z
Z
Li
J
J
Li
S
S
D002452:Cell Count; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000187:drug effects / Q000196:embryology*; D005333:Fetus; D006801:Humans; D016501:Neurites / Q000187:drug effects; D009474:Neurons / Q000166:cytology; D015032:Zinc / Q000494:pharmacology*
D015032:Zinc