title: The comparative sealing ability of hydroxyapatite cement, mineral trioxide aggregate, and super ethoxybenzoic acid as root-end filling materials.
abstract: A comparison was made of the ability of hydroxyapatite cement, mineral trioxide aggregate, and super ethoxybenzoic acid to prevent the leakage of bacteria from root canals, when used as root-end filling materials. The materials were tested in a double-chamber device in which a root segment connects the upper (delivery) chamber and the lower (receiving) chamber. The root segment was prepared by having the root canal instrumented to a #45 file, and a 3-mm-deep, root-end preparation placed at the apical foramen. The canal of each root segment was filled with gutta-percha, and the root-end preparation was filled with one of three test materials, mixed according to the manufacturer's directions. Negative controls were constructed with sticky wax sealing the apical foramen. A titered suspension of radioactively (3H-thymidine)-labeled bacteria (Enterococcus fecalis) was placed into the delivery chamber, and sterile saline was placed into the receiving chamber such that the apical third of each root section was immersed. At various time points, samples were taken from the receiving chamber, and measured for 3H activity. The results indicated that (a) all the test materials leaked significantly compared with the negative controls; and (b) there was no significant difference found between the leakage rates of the three materials tested.
authors.affiliation: Department of Endontology, Temple University School of Dentistry, Philadelphia, PA, USA.
authors.forename: C
authors.initials: C
authors.lastname: Mangin
authors.forename: C
authors.initials: C
authors.lastname: Yesilsoy
authors.forename: R
authors.initials: R
authors.lastname: Nissan
authors.forename: R
authors.initials: R
authors.lastname: Stevens
mesh_terms: D017607:Aluminum Compounds / Q000494:pharmacology; D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D017610:Calcium Compounds / Q000494:pharmacology; D003763:Dental Leakage / Q000517:prevention & control*; D015194:Diffusion Chambers, Culture; D004338:Drug Combinations; D013293:Enterococcus faecalis / Q000187:drug effects; D006801:Humans; D006882:Hydroxyapatites / Q000494:pharmacology*; D062425:Hydroxybenzoate Ethers; D062385:Hydroxybenzoates / Q000494:pharmacology; D010087:Oxides / Q000494:pharmacology; D012184:Retrograde Obturation / Q000379:methods; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D017640:Silicates / Q000494:pharmacology; D018709:Statistics, Nonparametric
chemical_list: D017607:Aluminum Compounds; D000891:Anti-Infective Agents, Local; D017610:Calcium Compounds; D004338:Drug Combinations; D006882:Hydroxyapatites; D062425:Hydroxybenzoate Ethers; D062385:Hydroxybenzoates; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C475044:hydroxyapatite cement; C086631:mineral trioxide aggregate; C015199:ethoxybenzoic acid