Sideroblastic anaemia with reactive thrombocytosis versus myelodysplastic/myeloproliferative disease.
The reported incidence of thrombocytosis among cases of refractory anaemia with ring sideroblasts (RARS) may be as high as 15%. We report four additional cases of this association, which appear to be hematologically heterogeneous. One patient clearly represents a case of RARS with reactive thrombocytosis. Two cases have features suggestive of the coincidental occurrence of essential thrombocythemia and RARS. The fourth case could be best classified as a subtype of myelodysplastic/myeloproliferative disease unclassifiable (MDS/MPD U). Only new biological or molecular markers will allow better differentiation between these disorders.
Pérez Sánchez
I
I
Pérez Corrala
A
A
Menarguez Palanca
J
J
Mayayo Crespo
M
M
Escudero Soto
A
A
Pintado Cros
T
T
D000368:Aged; D000369:Aged, 80 and over; D000756:Anemia, Sideroblastic / Q000150:complications / Q000175:diagnosis*; D001799:Blood Sedimentation; D001853:Bone Marrow / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003937:Diagnosis, Differential; D004900:Erythroblasts / Q000473:pathology; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007621:Karyotyping; D008297:Male; D009190:Myelodysplastic Syndromes / Q000145:classification / Q000175:diagnosis*; D009196:Myeloproliferative Disorders / Q000145:classification / Q000175:diagnosis*; D011014:Pneumonia / Q000150:complications; D013922:Thrombocytosis / Q000150:complications / Q000175:diagnosis*