Dendritic cells, new tools for vaccination.
Our rapidly expanding knowledge of the biology of the dendritic cell (DC), a major antigen-presenting cell connecting innate and adaptive immunity, suggests new possibilities for the development of vaccines and therapeutic strategies against pathogens, through the manipulation of their function in vivo, or the injection of the DC itself, once properly instructed ex vivo.
Colino
Jesus
J
Department of Pathology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.
Snapper
Clifford M
CM
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000938:Antigen-Presenting Cells / Q000276:immunology; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology* / Q000637:transplantation; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D007239:Infections / Q000628:therapy*; D008070:Lipopolysaccharides / Q000276:immunology / Q000627:therapeutic use; D008954:Models, Biological; D014611:Vaccination / Q000379:methods; D014612:Vaccines / Q000008:administration & dosage
D000276:Adjuvants, Immunologic; D008070:Lipopolysaccharides; D014612:Vaccines