title: Management options for persistent functional tumors.
abstract: This article describes in detail the current management of patients with functional pituitary tumors that demonstrate persistent function after surgical intervention. After providing a clear definition of "persistent function" for each specific type of tumor, the medical, surgical, and radiation options for each type are provided. Functional tumors include those that produce growth hormone, adrenocorticotrophic hormone, prolactin, and thyroid stimulating hormone.
authors.affiliation: Department of Neurosurgery, University of Michigan Health System, 1500 East Medical Center Drive, Room 2128, Taubman Center, Ann Arbor, MI 48109-0338, USA. wchndler@umich.edu
authors.forename: William F
authors.initials: WF
authors.lastname: Chandler
authors.forename: Ariel L
authors.initials: AL
authors.lastname: Barkan
authors.forename: David E
authors.initials: DE
authors.lastname: Schteingart
mesh_terms: D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D010911:Pituitary Neoplasms / Q000378:metabolism / Q000601:surgery*; D015175:Prolactinoma / Q000378:metabolism / Q000601:surgery
chemical_list: D007334:Insulin-Like Growth Factor I; D013007:Growth Hormone-Releasing Hormone