title: Abnormalities in the cerebral arterial system in osteogenesis imperfecta.
abstract: A 9-year-old girl with osteogenesis imperfecta (OI) type 4 was admitted to the hospital because of choreatic movement. Cerebral angiography demonstrated bilateral symmetrical stenosis of the proximal cavernous segment of internal carotid artery, prethrombotic occlusion of the M1 segment of left middle cerebral artery, and moyamoya-like collateral vascular structure arising from the right lenticulostriate arteries. After a literature review, these findings were interpreted as vasculopathic changes secondary to vascular fragility caused by the collagen abnormality in OI.
authors.affiliation: Department of Radiology, Division of Neuroradiology, Cerrahpasa Medical School, Istanbul University, Turkey.
authors.forename: Sait
authors.initials: S
authors.lastname: Albayram
authors.forename: Osman
authors.initials: O
authors.lastname: Kizilkilic
authors.forename: Halit
authors.initials: H
authors.lastname: Yilmaz
authors.forename: Beyhan
authors.initials: B
authors.lastname: Tuysuz
authors.forename: Naci
authors.initials: N
authors.lastname: Kocer
authors.forename: Civan
authors.initials: C
authors.lastname: Islak
mesh_terms: D002198:Capillary Fragility / Q000502:physiology; D002341:Carotid Artery Thrombosis / Q000175:diagnosis / Q000235:genetics; D002343:Carotid Artery, Internal / Q000473:pathology; D002426:Cavernous Sinus / Q000473:pathology; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D007089:Image Enhancement; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000235:genetics; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis* / Q000235:genetics; D020766:Intracranial Embolism / Q000175:diagnosis / Q000235:genetics; D008279:Magnetic Resonance Imaging; D009072:Moyamoya Disease / Q000175:diagnosis / Q000235:genetics; D009460:Neurologic Examination; D010013:Osteogenesis Imperfecta / Q000175:diagnosis* / Q000235:genetics; D012307:Risk Factors