title: The importance of adjusting for differences in proximal and distal contrast bolus arrival times in contrast-enhanced iliac artery magnetic resonance angiography.
abstract: We tested the hypothesis that differences in proximal and distal contrast bolus arrival times may result in insufficient vascular signal in the distal part of the aortoiliofemoral territory with routinely used timing techniques. The difference in arrival time of the contrast medium bolus between the aorta and the common femoral arteries was measured in 14 patients undergoing magnetic resonance angiography of the aortoiliac arteries. A dual-station test bolus technique adjusting for this difference was evaluated. The variation coefficient of the signal intensity in six defined locations and signal intensities (SI) normalised to fat were calculated. Comparisons were made with findings in 13 patients examined with a fluoroscopically triggered timing technique (BolusTrak, Philips Medical Systems, Best, The Netherlands). The difference in bolus arrival time between proximal and distal vessels was 0-7 s. In 3 of 14 patients it was 5.6-7 s. There was a tendency towards a lower mean variation coefficient in the dual-station group ( p=0.10). With both techniques, significantly lower SIs were measured in the femoral arteries compared with SIs in the superior part of the abdominal aorta. In two cases in the BolusTrak group, a distal vessel could not be delineated but was shown to be patent on a delayed scan. Differences in contrast medium arrival time along the vessel may be large enough to preclude visualisation of distal vessels unless there is compensation. A dual-station test bolus technique taking this into account was found to be feasible.
authors.affiliation: Department of Diagnostic Radiology, Uppsala University Hospital, Akademiska sjukhuset, 75185 Uppsala, Sweden. johan.wikstrom@radiol.uu.se
authors.forename: J
authors.initials: J
authors.lastname: Wikström
authors.forename: L
authors.initials: L
authors.lastname: Johansson
authors.forename: S
authors.initials: S
authors.lastname: Karacagil
authors.forename: H
authors.initials: H
authors.lastname: Ahlström
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta / Q000187:drug effects / Q000473:pathology; D001014:Aortic Aneurysm / Q000175:diagnosis; D001157:Arterial Occlusive Diseases / Q000175:diagnosis; D003287:Contrast Media / Q000008:administration & dosage*; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D005471:Fluoroscopy; D005500:Follow-Up Studies; D006801:Humans; D017543:Iliac Aneurysm / Q000175:diagnosis; D007083:Iliac Artery / Q000000981:diagnostic imaging* / Q000187:drug effects / Q000473:pathology; D007269:Injections, Intra-Arterial; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged; D011856:Radiographic Image Enhancement; D013997:Time Factors
chemical_list: D003287:Contrast Media