title: [Study of molecular genetics of the size of reproductive organs and litter size in the sow].
abstract: The mutations of ESR, PRLR and FSHR genes were investigated by SNP; 103 F2 sows were slaughtered and their reproductive organs were determined; the litter size of sow was recorded. The linkage between mutations of genes and size of reproductive organ, litter size was analyzed. The results revealed: these sows that could provide more piglets with bigger reproductive organs usually carried genotype like as genotype BB on the sites of ESR, FSHRB and the genotype AA on the sites of ESRB and PRLR, that is, the genotype of BB on the sites of ESR or FSHRB in sow was not only helpful to promote growth of reproductive organs, but also benefit to improve litter size; The size of productive organs and litter size of the sow with genotype AA on the sites of ESRB or PRLR were significantly higher than those of sow with genotype AB or BB.
authors.affiliation: College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. sjxiaozhang@mail.hzag.edu.cn
authors.forename: Shu-Jun
authors.initials: SJ
authors.lastname: Zhang
authors.forename: Yuan-Zhu
authors.initials: YZ
authors.lastname: Xiong
authors.forename: Chang-Yan
authors.initials: CY
authors.lastname: Deng
authors.forename: Fan-Tong
authors.initials: FT
authors.lastname: Zeng
authors.forename: Xiang-Pin
authors.initials: XP
authors.lastname: Qiu
authors.forename: Sen-Mu
authors.initials: SM
authors.lastname: Xiao
authors.forename: Yu
authors.initials: Y
authors.lastname: Xia
authors.forename: Jian-Xiang
authors.initials: JX
authors.lastname: Xu
authors.forename: Zheng
authors.initials: Z
authors.lastname: Ruan
mesh_terms: D000818:Animals; D005260:Female; D005838:Genotype; D008098:Litter Size / Q000235:genetics*; D008297:Male; D009154:Mutation; D010053:Ovary / Q000378:metabolism*; D010298:Parity / Q000235:genetics; D020641:Polymorphism, Single Nucleotide; D011960:Receptors, Estrogen / Q000235:genetics; D011962:Receptors, FSH / Q000235:genetics; D011981:Receptors, Prolactin / Q000235:genetics; D013552:Swine / Q000235:genetics* / Q000254:growth & development; D014599:Uterus / Q000378:metabolism*
chemical_list: D011960:Receptors, Estrogen; D011962:Receptors, FSH; D011981:Receptors, Prolactin