Use of tumor-activated hepatic stellate cell as a target for the preclinical testing of anti-angiogenic drugs against hepatic tumor development.
Olaso
Elvira
E
Department of Cell Biology, Basque Country University School of Medicine and Dentistry, Leioa, Spain.
Vidal-Vanaclocha
Fernando
F
D020533:Angiogenesis Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002478:Cells, Cultured / Q000187:drug effects; D017077:Culture Media, Conditioned / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D016228:Endothelial Growth Factors / Q000032:analysis / Q000494:pharmacology; D004730:Endothelium, Vascular / Q000473:pathology; D006133:Growth Substances / Q000494:pharmacology; D036341:Intercellular Signaling Peptides and Proteins / Q000032:analysis / Q000494:pharmacology; D008114:Liver Neoplasms, Experimental / Q000517:prevention & control / Q000556:secondary*; D008222:Lymphokines / Q000032:analysis / Q000494:pharmacology; D008297:Male; D051379:Mice; D009363:Neoplasm Proteins / Q000032:analysis / Q000494:pharmacology; D009389:Neovascularization, Pathologic / Q000188:drug therapy* / Q000473:pathology; D020286:Pericytes / Q000187:drug effects*; D014407:Tumor Cells, Cultured / Q000378:metabolism / Q000637:transplantation; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D020533:Angiogenesis Inhibitors; D017077:Culture Media, Conditioned; D016228:Endothelial Growth Factors; D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D009363:Neoplasm Proteins; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors