title: Hadamard transform microchip electrophoresis combined with diode laser fluorometry.
abstract: The application of a Hadamard transform technique to microchip electrophoresis is described. The sample is electrokinetically injected into a separation channel and is then detected by diode laser-induced fluorometry. The sample and buffer solutions are introduced into the channel by controlling the high voltages applied to the solutions, according to a code determined by a Hadamard matrix. The S/N ratio of the signal in the electropherogram can be improved by a factor of 5 in comparison with that obtained by a conventional single-injection method, although an 8-fold improvement is theoretically predicted when a 255-order matrix is used.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, 812-8581 Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Hata
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Kichise
authors.forename: Takashi
authors.initials: T
authors.lastname: Kaneta
authors.forename: Totaro
authors.initials: T
authors.lastname: Imasaka