Relapse of ocular symptoms after remission of myasthenia gravis--a comparison of relapsed and complete remission cases.
Extended thymectomy and high-dose alternate-day prednisolone administration may increase the chance of remission in myasthenia gravis (MG) patients. In cases of remission, ocular symptoms sometimes reappear after a gradual decrease or discontinuation of prednisolone administration. We compared relapsed patients with those who experienced complete remission. We found that the period from onset of MG to thymectomy and initiation of prednisolone administration was longer in the relapsed cases, which suggests that early thymectomy and administration of prednisolone can lead to a superior outcome in MG patients.
Wakata
Nobuo
N
The Fourth Department of Internal Medicine, Toho University School of Medicine, 2-17-6 Oohashi, Meguro-ku, Tokyo 153-8515, Japan. waka@oha.toho-u.ac.jp
Iguchi
Hiroaki
H
Sugimoto
Hideki
H
Nomoto
Nobuatu
N
Kurihara
Teruyuki
T
D000293:Adolescent; D000328:Adult; D005128:Eye Diseases / Q000209:etiology* / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D011239:Prednisolone / Q000008:administration & dosage / Q000494:pharmacology*; D012008:Recurrence; D013934:Thymectomy
D005938:Glucocorticoids; D011239:Prednisolone