title: One-shot memory in hippocampal CA3 networks.
abstract: The hippocampus plays a crucial role in the encoding and retrieval of episodic memory. In this issue of Neuron, Nakazawa and coworkers show that synaptic modification in hippocampal CA3 neurons is critical for immediate storage of information, a key feature of episodic memory.
authors.affiliation: Centre for the Biology of Memory, Norwegian University of Science and Technology, 7491, Trondheim, Norway.
authors.forename: Edvard I
authors.initials: EI
authors.lastname: Moser
authors.forename: May Britt
authors.initials: MB
authors.lastname: Moser
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D017774:Long-Term Potentiation / Q000502:physiology; D018782:Maze Learning; D008568:Memory / Q000502:physiology*; D051379:Mice; D009154:Mutation; D009415:Nerve Net / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D017966:Pyramidal Cells / Q000378:metabolism / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics / Q000378:metabolism; D013569:Synapses / Q000502:physiology*
chemical_list: C409466:NR1 NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate