title: A rare case of a pulmonary granular cell tumor presenting as a coin lesion.
abstract: A 38-year-old man was found to show a well-defined oval-shaped homogeneous dense mass (20 x 30 mm) in the left upper lung field on chest X-ray. Left upper divisionectomy was performed under video-assisted thoracic surgery. Histology showed that the tumor cells had abundant eosinophilic granular cytoplasm, and were immunopositive for neuron-specific enolase, CD56, S-100 protein, and chromogranin. The proportion of Ki-67 positive cells was < 1%. An electron-microscopic examination showed many membrane-bound whorls in the cytoplasm. Although this was a very rare case presenting as an asymptomatic coin lesion, the histological features were the same as those demonstrated for granular cell tumor at common sites.
authors.affiliation: Department of Surgery, Sendai Kosei Hospital, Sendai, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Hosaka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Niikawa
authors.forename: Jotaro
authors.initials: J
authors.lastname: Shibuya
authors.forename: Takashi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Masashi
authors.initials: M
authors.lastname: Handa
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000473:pathology