title: Determination of neonicotinoid pesticide residues in vegetables and fruits with solid phase extraction and liquid chromatography mass spectrometry.
abstract: A rapid and simple extraction method for the simultaneous analysis of five neonicotinoid insecticides has been developed. Twelve different fruit and vegetable matrixes were extracted with methanol and cleaned up using a graphitized carbon solid phase extraction cartridge loading with a 20% methanol solution. The concentrated eluate after methanol elution was then analyzed for pesticide residues by liquid chromatography/mass spectrometry in the APCI positive mode. The five pesticides including nitenpyram, thiamethoxam, imidacloprid, acetamiprid, and thiacloprid were recovered at 70-95% at spike levels of 0.1 and 1 mg/kg in bell pepper, cucumber, eggplant, grape, grapefruit, Japanese radish, peach, pear, potato, rice, and tomato. Relative standard deviations were less than 10% for all of the recovery tests. The proposed method is fast, easy to perform, and could be utilized for regular monitoring of pesticide residues.
authors.affiliation: Osaka Prefectural Institute of Public Health, 1-3-69 Nakamichi, Higashinari, Osaka 5370025, Japan. obana@iph.pref.osaka.jp
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Obana
authors.forename: Masahiro
authors.initials: M
authors.lastname: Okihashi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Akutsu
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Hori
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D005506:Food Contamination / Q000032:analysis*; D005638:Fruit / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007306:Insecticides / Q000032:analysis; D010573:Pesticide Residues / Q000032:analysis*; D013997:Time Factors; D014675:Vegetables / Q000737:chemistry*
chemical_list: D007306:Insecticides; D010573:Pesticide Residues