title: Polysiloxane-supported NAD(P)H model 1-benzyl-1,4-dihydronicotinamide: synthesis and application in the reduction of activated olefins.
abstract: A new polysiloxane-supported NAD(P)H model, 1-benzyl-1,4-dihydronicotinamide, was designed and synthesized, which can efficiently reduce many activated olefins under mild conditions. The most advantageous features of this new polysiloxane-supported reductant are (i) easy workup and separation of the reaction products and (ii) good potential for recycling use of the reductant, which makes this new polysiloxane-supported NAD(P)H model a promising alternative both in research laboratories and in industrial processes.
authors.affiliation: State Key Laboratory of Elemento-Organic Chemistry, Department of Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Baolian
authors.initials: B
authors.lastname: Zhang
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Zhu
authors.forename: Jin-Yong
authors.initials: JY
authors.lastname: Lu
authors.forename: Jiaqi
authors.initials: J
authors.lastname: He
authors.forename: Peng G
authors.initials: PG
authors.lastname: Wang
authors.forename: Jin-Pei
authors.initials: JP
authors.lastname: Cheng
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D009243:NAD / Q000031:analogs & derivatives*; D009249:NADP; D010084:Oxidation-Reduction; D012833:Siloxanes / Q000737:chemistry
chemical_list: C445701:1-benzyl-1,4-dihydronicotinamide; D000475:Alkenes; D012833:Siloxanes; D009243:NAD; D009249:NADP