[Helicobacter pylori infection and idiopathic thrombocytopenic purpura].
The prevalence of Helicobacter pylori(H. pylori) infection and the effect of its eradication on platelet count in 51 chronic idiopathic thrombocytopenic purpura(ITP) and 9 secondary autoimmune thrombocytopenic purpura(SAITP) patients, were investigated. H. pylori infection was found in 31 ITP patients(60.8%) and in two SAITP(22.2%). H. pylori eradication was obtained in 24 of 26 infected ITP patients. 14 of 24 H. pylori-eradicated patients(58.3%) showed a significant increase in platelet count 6 months after eradication, however two infected patients with SAITP did not show platelet increase. This response was maintained in all responding patients throughout the follow-up period(median 20 months).
Kohda
Kyuhei
K
Department of Gastroenterology and Hematology, Asahikawa Red Cross Hospital.
Niitsu
Yoshiro
Y
D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications*