title: Fournier's gangrene: an analysis of repeated surgical debridement.
abstract: OBJECTIVE
  We wanted to determine if there was a difference in outcome for those patients with Fournier's disease who underwent numerous debridements as opposed to only one initial debridement.
  
  
  METHODS
  The records of 19 patients with the diagnosis of Fournier's gangrene were reviewed retrospectively at our institution. Special attention was placed on demographic data, primary managing service, as well as wound cultures, and the number and timing of surgical debridements. Patients were also classified by a collection of variables at presentation and given a score named the Fournier's Severity Index. We utilised the Fournier's Severity Index (FSI) as developed by Laor et al. which included a number of vital sign data as well as laboratory values collected at admission in the emergency room.
  
  
  RESULTS
  The average FSI was 9.1 ranging from 0 to 15. The mean FSI of survivors was 8.6 versus 12.4 of non-survivors. The surgical management of this disease process was also critically examined. The average number of repeated debridements was 3.5 ranging from 1 to 8. Both the FSI and the number of debridements were attempted to be used to predict outcome. Outcome was measured in the variables length of stay (days) and survival. A regression analysis revealed the number of debridements to be positively related to the length of stay (LOS). This was the opposite as expected at the beginning of the study. Also FSI was not predictive of LOS.
  
  
  CONCLUSIONS
  Fournier's gangrene is a disease process with a wide variability in presentation. The FSI does give some indication about the likelihood of survival based on variables which can be recorded upon presentation. It also provides an efficient way to characterize the acuity of presentation and compare patients. While the repeated nature of debridements may be considered the accepted standard of care in these patients, this was not found to be predictive of outcome.
authors.affiliation: Department of Urology, Temple University Medical Center, Philadelphia, PA 19140, USA.
authors.forename: Sam N
authors.initials: SN
authors.lastname: Chawla
authors.forename: Christina
authors.initials: C
authors.lastname: Gallop
authors.forename: Jack H
authors.initials: JH
authors.lastname: Mydlo
mesh_terms: D003646:Debridement; D005260:Female; D018934:Fournier Gangrene / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D012086:Reoperation; D012189:Retrospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate