title: Symmetrical reconversion: measuring cross-correlation rates with enhanced accuracy.
abstract: A new strategy has been developed to measure cross-correlation rates with much enhanced accuracy. The method relies on the use of four complementary experiments. Errors due to pulse miscalibration and to uncontrolled attenuation factors associated with relaxation are cancelled out. Problems due to violations of the secular approximation are greatly alleviated. The method has been applied to the measurement of N/NH (CSA/DD) cross-correlated relaxation rates in human ubiquitin.
authors.affiliation: Département de Chimie, associé au CNRS, Ecole Normale Supérieure, 24 rue Lhomond, 05 F-75231, Paris Cedex, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Pelupessy
authors.forename: Guillermo Minguez
authors.initials: GM
authors.lastname: Espallargas
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Bodenhausen
mesh_terms: D016880:Anisotropy; D002247:Carbon Isotopes; D006801:Humans; D009587:Nitrogen Isotopes; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D025801:Ubiquitin / Q000737:chemistry*
chemical_list: D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D025801:Ubiquitin