title: Copper-catalyzed anti-stereocontrolled ring opening of oxabicyclic alkenes with grignard reagents.
abstract: [reaction: see text] A general copper-catalyzed procedure for the stereoselective ring opening of [2.2.1]-oxabicyclic alkenes with Grignard reagents is described. In the presence of catalytic amounts of CuCl/PPh(3) the reaction occurs with very high or complete anti selectivity in all cases.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.
authors.forename: Ramón
authors.initials: R
authors.lastname: Gómez Arrayás
authors.forename: Silvia
authors.initials: S
authors.lastname: Cabrera
authors.forename: Juan C
authors.initials: JC
authors.lastname: Carretero