N-ras mutation in a canine lymphoma: short communication.
Lymphomas of dogs were investigated by molecular genetic methods. Regions of exon 1 and 2 of the N-ras gene, which harbours the mutation hot spots (codons 12, 13 and 61) were screened. A GGT [symbol: see text] GAT (glycine [symbol: see text] aspartic acid) mutation in codon 13 was present in a multicentric-type lymphoma of a 1-year-old male dog.
Mayr
B
B
Institute for Animal Breeding and Genetics, Veterinary University, Veterinärplatz 1, A-1210 Vienna, Austria. Burkhard.Mayr@vu-wien.ac.at
Holzheu
M
M
Schaffner
G
G
Reifinger
M
M
D000818:Animals; D017931:DNA Primers; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D011905:Genes, ras / Q000235:genetics*; D008223:Lymphoma / Q000235:genetics / Q000662:veterinary*; D008297:Male; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000662:veterinary
D017931:DNA Primers