[Prognosis of outcome of radical surgery in patients with lung cancer associated with severe complications and concurrent diseases].
From 1981 to 2001 (20 years) 1307 patients with lung cancer underwent surgery. Postoperative lethality was 1.7% (after 635 pneumonectomies it was 2.4%, after 672 lob- and bilobectomies--1.2%). Medical histories of 171 operated patients with severe concomitant diseases was studied to analyze surgical outcomes depending on such important factors as age, concomitant diseases, surgical trauma. It is demonstrated that age of patients is not a factor of postoperative prognosis, but concomitant diseases and surgical trauma (i.e. pneumonectomy) are important factors of it. Results of surgery in the group of patients with four and more concomitant diseases after pneumonectomy were most unfavorable (lethality was 22.9%). In less severe surgical trauma (lobectomy) results of surgery were more favorable. It is concluded that surgery in patients with a lot of concomitant diseases must be less radical to obtain lower lethality. Radicality of treatment in these patients is ensured due to complex chemo- and radiation therapy after surgery.
Shevchenko
Iu L
IuL
Chistov
L V
LV
Borisov
I A
IA
Ablitsov
Iu A
IuA
Kuznetsov
N A
NA
Gorbatov
O I
OI
Nevzorova
E V
EV
Agikian
S S
SS
Anisimova
O V
OV
D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects; D001145:Arrhythmias, Cardiac / Q000150:complications; D001157:Arterial Occlusive Diseases / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008175:Lung Neoplasms / Q000150:complications* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy / Q000009:adverse effects / Q000379:methods; D011237:Predictive Value of Tests; D011379:Prognosis; D012131:Respiratory Insufficiency / Q000150:complications; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
Prognozirovanie iskhodov radikal'nykh operatsiĭ u bol'nykh rakom lëgkogo s tiazhëlymi sochetannymi i konkuriruiushchimi zabolevaniiami.