title: Prenatal diagnosis by DNA polymorphism analysis of complete mole with coexisting twin.
abstract: Partial mole is distinguishable from complete mole with coexisting normal twin after delivery by DNA polymorphysm analysis. Our patient had chorionic villus sampling of a molar-appearing placenta with coexisting fetus at 12.3 weeks. Absent maternal alleles confirmed a diandrogenetic complete mole. Prenatal DNA diagnosis of complete mole is possible and clinically useful.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, USA.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Wax
authors.forename: Michael G
authors.initials: MG
authors.lastname: Pinette
authors.forename: Renée
authors.initials: R
authors.lastname: Chard
authors.forename: Jacquelyn
authors.initials: J
authors.lastname: Blackstone
authors.lastname: Do
authors.forename: Angelina
authors.initials: A
authors.lastname: Cartin
mesh_terms: D000328:Adult; D015193:Chorionic Villi Sampling; D004247:DNA / Q000235:genetics*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000235:genetics; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011296:Prenatal Diagnosis / Q000379:methods; D014427:Twins; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000235:genetics*
chemical_list: D004247:DNA