title: Severe proliferative retinopathy progressing to blindness in a japanese woman with takayasu disease.
abstract: OBJECTIVE
  To report a patient with Takayasu disease with severe proliferative retinopathy progressing to bilateral blindness. A 57-year-old Japanese woman suffering from Takayasu disease for 16 years manifested severe proliferative retinopathy in both eyes, leading to blindness due to optic atrophy.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 57-year-old Japanese woman suffering from Takayasu disease for 16 years underwent a comprehensive opthalmologic examination. Panretinal photocoagulation and vitrectomy were performed on both eyes.
  
  
  METHODS
  Institutional practice.
  
  
  RESULTS
  At initial examination, the patient was found to have severe proliferative retinopathy with tractional retinal detachment in both eyes. The retinal detachments were repaired by the vitrectomy, however, the patient developed bilateral blindness due to optic atrophy.
  
  
  CONCLUSIONS
  Patients with a long history of Takayasu disease can demonstrate severe proliferative retinopathy that may be resistant to photocoagulation and/or vitreous surgery. Ocular ischemia can lead to blindness from ischemic optic neuropathy.
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Japan.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Kuwahara
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imamura
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Okamura
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Sakai
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Ikeda
mesh_terms: D001766:Blindness / Q000209:etiology*; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007564:Japan; D017075:Laser Coagulation; D008875:Middle Aged; D009896:Optic Atrophy / Q000209:etiology; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013625:Takayasu Arteritis / Q000150:complications* / Q000175:diagnosis / Q000208:ethnology; D014821:Vitrectomy