Carboxylate-directed highly stereoselective homogeneous hydrogenation of cyclic olefins with Wilkinson's catalyst.
A highly efficient diastereoselective, carboxylate-directed homogeneous hydrogenation of cyclic olefins with use of Wilkinson's catalyst is described. Under the optimized reaction conditions, better than 99% de was achieved. The experimental protocol is very simple and readily amenable to scale-up. [reaction: see text]
Zhang
Mingbao
M
Department of Chemistry Research, Bayer Research Center, 400 Morgan Lane, West Haven, CT 06516, USA. mingbao.zhang@bayer.com
Zhu
Lei
L
Ma
Xin
X
Dai
Miao
M
Lowe
Derek
D