title: Upper gastrointestinal cancer risk in familial adenomatous polyposis.
abstract: Familial adenomatous polyposis has a known risk of colorectal carcinoma. Less well recognized, however, is the association with duodenal polyps and their subsequent malignant degeneration. While frequent endoscopic surveillance is acceptable, a case of early malignant transformation is presented, and the argument for prophylactic preemptive pancreaticoduodenectomy is made.
authors.affiliation: Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.
authors.forename: T Jeffery
authors.initials: TJ
authors.lastname: Wieman
authors.forename: Scott W
authors.initials: SW
authors.lastname: Taber
authors.forename: Donald N
authors.initials: DN
authors.lastname: Reed
authors.forename: Gary C
authors.initials: GC
authors.lastname: Vitale
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000601:surgery; D000328:Adult; D005770:Gastrointestinal Neoplasms / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012306:Risk