title: Observation of the cascaded atomic-to-global length scales driving protein motion.
abstract: Model studies of the ligand photodissociation process of carboxymyoglobin have been conducted by using amplified few-cycle laser pulses short enough in duration (<10 fs) to capture the phase of the induced nuclear motions. The reaction-driven modes are observed directly in real time and depict the pathway by which energy liberated in the localized reaction site is efficiently channeled to functionally relevant mesoscale motions of the protein.
authors.affiliation: Department of Physics and Astronomy, University of Rochester, Bausch & Lomb Hall, Rochester, NY 14627-0171, USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Armstrong
authors.forename: J P
authors.initials: JP
authors.lastname: Ogilvie
authors.forename: M L
authors.initials: ML
authors.lastname: Cowan
authors.forename: A M
authors.initials: AM
authors.lastname: Nagy
authors.forename: R J D
authors.initials: RJ
authors.lastname: Miller
mesh_terms: D000818:Animals; D002248:Carbon Monoxide; D003574:Cytochrome c Group / Q000737:chemistry*; D007834:Lasers; D009211:Myoglobin / Q000737:chemistry*
chemical_list: D003574:Cytochrome c Group; D009211:Myoglobin; D002248:Carbon Monoxide