title: [Clonal expansion of Neisseria meningitidis W135. Epidemiological implications for the African meningitis belt].
abstract: Meningococcal meningitis occur as large epidemics in the "African meningitis belt" described by L. Lapeyssonnie. Neisseria meningitidis serogroup A, clone III-I, was involved in recent epidemics and immunization with A and C vaccine was therefore adequate. However, we report here the emergence of a new clone of N. meningitidis of serogroup W135 during the 2001 epidemics in Niger and in Burkina Faso and discuss the implications of this new epidemiological feature for future surveillance and vaccine strategies.
authors.affiliation: Association pour la médecine préventive, Institut Pasteur, 25-28 rue du Dr Roux, 75724 Paris, France.
authors.forename: I Parent
authors.initials: IP
authors.lastname: du Châtelet
authors.forename: J M
authors.initials: JM
authors.lastname: Alonso
authors.forename: M K
authors.initials: MK
authors.lastname: Taha
mesh_terms: D015373:Bacterial Typing Techniques; D002050:Burkina Faso / Q000453:epidemiology; D021821:Communicable Diseases, Emerging / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control; D004196:Disease Outbreaks / Q000517:prevention & control / Q000706:statistics & numerical data*; D006801:Humans; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control; D022401:Meningococcal Vaccines; D017720:Molecular Epidemiology; D038582:Neisseria meningitidis, Serogroup W-135 / Q000145:classification / Q000235:genetics; D009548:Niger / Q000453:epidemiology; D011159:Population Surveillance; D011634:Public Health; D012703:Serotyping; D014611:Vaccination / Q000379:methods / Q000592:standards
chemical_list: D022401:Meningococcal Vaccines
vernacular_title: Expansion clonale de Neisseria meningitidis W135. Implications épidémiologiques pour la ceinture africaine de la méningite.