title: [Improvement of health-related quality of life in patients with obstructive sleep apnea syndrome under CPAP therapy].
abstract: BACKGROUND
  Only poor data regarding changes in quality of life in patients with obstructive sleep apnea syndrome (OSAS) under continuous positive airway pressure (CPAP) therapy concerning long-term effects are available.
  
  
  METHODS
  In this study, 85 patients were evaluated before and under CPAP therapy using the Visual Analog Scale (VAS) Quality of Life, the Nottingham Health Profile (NHP), and the Quality of Life Index (QL-Index). The results of patients with continuous usage of CPAP (n = 66) were compared with a control group of patients who discontinued CPAP therapy (n = 19).
  
  
  RESULTS
  VAS (before CPAP 56.9 +/- 27.0, under CPAP 67.2 +/- 21.8 mm; p = 0.027) as well as the NHP dimensions "Energy" (before CPAP 44.2 +/- 39.5, under CPAP 25.0 +/- 34.2 points; p < 0.001), "Emotional reactions" (before CPAP 24.7 +/- 22.5, under CPAP 11.8 +/- 18.8 points; p < 0,001), and "Sleep problems" (before CPAP 32.0 + 30.0, under CPAP 21.5 + 27.2 points; p = 0.005) showed a significant improvement after 16 +/- 9-month follow-up. In the control group, none of the instruments displayed a significant change. A correlation between CPAP compliance (mask hours) and changes in quality of life was not detected.
  
  
  CONCLUSIONS
  Thus, even suboptimal CPAP usage might bring benefit regarding quality of life. As not all health-related instruments or dimensions were able to display the effects on quality of life, there is a need to translate and validate disease-specific instruments into the German language.
authors.affiliation: Medizinische Klinik III, Schwerpunkt Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin, Berufsgenossenschaftliche Kliniken Bergmannsheil, Klinikum der Ruhr-Universität Bochum. justus.dezeeuw@rurr-uni-bochum.de
authors.forename: Justus
authors.initials: J
authors.lastname: de Zeeuw
authors.forename: Henning Thomas
authors.initials: HT
authors.lastname: Baberg
authors.forename: Daniela Jennifer
authors.initials: DJ
authors.lastname: Kempkens
authors.forename: Oliver
authors.initials: O
authors.lastname: Schmalz
authors.forename: Hans-Werner
authors.initials: HW
authors.lastname: Duchna
authors.forename: Maritta
authors.initials: M
authors.lastname: Orth
authors.forename: Joachim
authors.initials: J
authors.lastname: Kugler
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schultze-Werninghaus
authors.forename: Kurt
authors.initials: K
authors.lastname: Rasche
mesh_terms: D000328:Adult; D000368:Aged; D016001:Confidence Intervals; D003627:Data Interpretation, Statistical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010349:Patient Compliance; D017286:Polysomnography; D011175:Positive-Pressure Respiration; D011788:Quality of Life; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D011795:Surveys and Questionnaires; D013997:Time Factors
vernacular_title: Verbesserung der gesundheitsspezifischen Lebensqualität unter CPAP-Therapie bei Patienten mit obstruktivem Schlafapnoesyndrom.