Interferon-induced sarcoidosis.
Interferons have been used as therapy of both malignant and nonmalignant diseases and commonly in the treatment of hepatitis C virus infection. Although the most commonly encountered side effects of interferon therapy include nonspecific constitutional symptoms, pulmonary involvement is rare. Here, we provide two documented cases of sarcoidosis appearing in patients receiving interferon therapy for hepatitis C infection, because there have only been a few reports of this association. Physicians should be aware of this uncommon yet clinically important complication, because imaging these patients may obviate more invasive procedures.
Rubinowitz
Ami N
AN
the Department of Radiology, New York University Medical Center, New York, NY 10016, USA. ami.rubinowitz@med.nyu.edu
Naidich
David P
DP
Alinsonorin
Cesar
C
D000998:Antiviral Agents / Q000009:adverse effects*; D005260:Female; D006526:Hepatitis C / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007372:Interferons / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D017565:Sarcoidosis, Pulmonary / Q000139:chemically induced* / Q000175:diagnosis
D000998:Antiviral Agents; D007372:Interferons