title: Radiologic correlates of symptom-based diagnostic criteria for chronic rhinosinusitis.
abstract: OBJECTIVE
  In 1997, the Task Force on Rhinosinusitis (TFR) set forth symptom-based diagnostic guidelines for chronic rhinosinusitis (CRS). In the present study, we examined radiologic correlates of the TFR diagnostic criteria for rhinosinusitis.
  
  
  METHODS
  One hundred twenty-five consecutive patients undergoing computed tomography (CT) scans of the sinuses were studied at Oregon Health and Science University. Patients were evaluated prospectively with a questionnaire based on the TFR criteria, and their CT scans were graded according to the Lund-Mackay scoring system.
  
  
  RESULTS
  Of the 125 patients, 115 met the symptom criteria for CRS. However, 40 of 115 had negative scans (Lund-McKay score, 0) despite meeting the diagnostic criteria for rhinosinusitis. Of 115, 75 had positive scans (Lund-McKay score, >1). Of the 10 patients who had negative diagnoses for rhinosinusitis, 9 had a positive CT scan. The Kappa coefficient was -0.103 (+/-95% confidence interval, -0.201 to -0.004), indicating poor agreement between CRS positivity and CT positivity. The sensitivity of TFR criteria for detecting a positive scan was 89%, but the specificity was poor at only 2%.
  
  
  CONCLUSIONS
  Based on these pilot data, it appears that the specificity and predictive value of the current TFR criteria may not be adequate to serve as a diagnostic standard for rhinosinusitis. Additional validating data may provide guidance for improving the sensitivity and specificity of symptom-based diagnostic instruments for rhinosinusitis.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, Portland, USA. hwangp@ohsu.edu
authors.forename: Peter H
authors.initials: PH
authors.lastname: Hwang
authors.forename: Sande B
authors.initials: SB
authors.lastname: Irwin
authors.forename: Susan E
authors.initials: SE
authors.lastname: Griest
authors.forename: James E
authors.initials: JE
authors.lastname: Caro
authors.forename: Gary M
authors.initials: GM
authors.lastname: Nesbit
mesh_terms: D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012220:Rhinitis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D012852:Sinusitis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011795:Surveys and Questionnaires; D014057:Tomography, X-Ray Computed