title: [Preliminary experience with O.P.A.T. (Outpatient parenteral antimicrobial-drug therapy) in infective endocarditis].
abstract: The authors evaluated the efficacy and safety of an OPAT program in a small group of patients affected by infective endocarditis. Three patients were considered eligible for the treatment; i.e. they had a stable hemodynamic balance and no embolic events. Streptococcus spp. grew in blood cultures of two patients, while blood cultures were negative in the third patient. Long-acting antibiotics were used and all patients recovered from the infection without adverse events. The treatment was efficacious and safe. This preliminary experience suggests that OPAT programs can be promoted in infective endocarditis with advantage. Strictness and caution are necessary in screening and monitoring patients.
authors.affiliation: U.O. di Malattie Infettive, A.O. S.G. Moscati, Avellino.
authors.forename: F S
authors.initials: FS
authors.lastname: Nigro
authors.forename: G
authors.initials: G
authors.lastname: Buonopane
authors.forename: M
authors.initials: M
authors.lastname: Iandoli
authors.forename: M
authors.initials: M
authors.lastname: Matarazzo
authors.forename: P
authors.initials: P
authors.lastname: Maio
authors.forename: F
authors.initials: F
authors.lastname: Siano
authors.forename: M L
authors.initials: ML
authors.lastname: Taddeo
authors.forename: E
authors.initials: E
authors.lastname: Zuccardi
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004696:Endocarditis / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Esperienze preliminari di trattamento delle endocarditi infettive in OPAT.