title: Variability in phenolic composition of Hypericum androsaemum.
abstract: The methanolic extracts of fifteen Hypericum androsaemum samples, growing spontaneously or cultivated in Portugal, were analysed by HPLC/DAD, allowing the identification of 9 phenolic compounds and the detection of 6 phloroglucinols. Total amounts of phenolics found ranged from 11 to 39 g/kg, and the influence of some factors which may be responsible for this variation is discussed. The individual compounds were also quantified. Four different phenolic profiles were found concerning both qualitative and quantitative composition, indicating the possible existence of chemical polymorphism.
authors.affiliation: CEQUP/Serviço de Farmacognosia, Faculdade de Farmácia, Universidade do Porto, R. Anibal Cunha 164, 4050-047 Porto, Portugal.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Valentão
authors.forename: Alberto
authors.initials: A
authors.lastname: Dias
authors.forename: Manuel
authors.initials: M
authors.lastname: Ferreira
authors.forename: Branca
authors.initials: B
authors.lastname: Silva
authors.forename: Paula B
authors.initials: PB
authors.lastname: Andrade
authors.forename: M Lourdes
authors.initials: ML
authors.lastname: Bastos
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Seabra
mesh_terms: D002851:Chromatography, High Pressure Liquid; D006801:Humans; D020902:Hypericum; D010636:Phenols / Q000737:chemistry*; D010696:Phloroglucinol / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
chemical_list: D010636:Phenols; D010936:Plant Extracts; D010696:Phloroglucinol