Di-iron-tyrosyl radical ribonucleotide reductases.
New insights have been gained into the formation of the di-iron tyrosyl radical cofactor, which is essential for nucleotide reduction in the class I ribonucleotide reductases. Recent advances include Insight into the function of the tyrosyl radical in initiation of nucleotide reduction.
Stubbe
JoAnne
J
Chemistry and Department, Massachusetts Institute of Technology, Cambridge, MA 01239, USA.
D004926:Escherichia coli / Q000201:enzymology; D005609:Free Radicals; D010084:Oxidation-Reduction; D012264:Ribonucleotide Reductases / Q000737:chemistry*; D014443:Tyrosine / Q000737:chemistry; D015003:Yeasts / Q000201:enzymology
D005609:Free Radicals; D014443:Tyrosine; D012264:Ribonucleotide Reductases