title: Single route to chiral syn- and anti-2-amino-1,2-diphenylethanols via a new stereodivergent opening of trans-1,2-diphenyloxirane.
abstract: Oxiranyl ring opening of trans-stilbene oxide gave rise to anti- or syn-2-bromo-1,2-diphenylethanols, using either MgBr(2).Et(2)O or MgBr(2).Et(2)O, NaBr, and KBr with Amberlyst 15, respectively. Starting from optically pure (R,R)-trans-stilbene oxide, (1R,2R)- and (1R,2S)-2-amino-1,2-diphenylethanols were obtained in high yield and ee.
authors.affiliation: Dipartimento di Chimica, Università degli Studi della Basilicata, via Nazario Sauro 85, 85100 Potenza, Italy. lupattelli@unibas.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Lupattelli
authors.forename: Carlo
authors.initials: C
authors.lastname: Bonini
authors.forename: Leonilde
authors.initials: L
authors.lastname: Caruso
authors.forename: Augusto
authors.initials: A
authors.lastname: Gambacorta