title: Gallium-67 demonstration of extensive soft-tissue involvement of multiple myeloma.
abstract: A 46-year-old woman with multiple myeloma presented with neurological symptoms in the right upper extremity. After MR imaging of the cervical spine failed to show the cause of her symptoms, Ga-67 scintigraphy demonstrated increased uptake in multiple areas including the right supraclavicular region and bilateral lower extremities. Histology of the specimen obtained from the left thigh proved soft-tissue involvement of myeloma, and extensive extramedullary involvement was diagnosed. Radiotherapy to the right supraclavicular mass relieved her symptoms. Although Ga-67 scintigraphy is generally considered of limited value in multiple myeloma, this modality contributed to the development of an appropriate strategy in this patient with extensive extramedullary involvement.
authors.affiliation: Department of Radiology, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan. makohoso@saitama-med.ac.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Hosono
authors.forename: Kikuo
authors.initials: K
authors.lastname: Machida
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Inoue
authors.forename: Norinari
authors.initials: N
authors.lastname: Honda
authors.forename: Takeo
authors.initials: T
authors.lastname: Takahashi
authors.forename: Akio
authors.initials: A
authors.lastname: Kashimada
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ohtawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ohno
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yamano
mesh_terms: D002951:Citrates; D005260:Female; D005708:Gallium; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D013848:Thigh / Q000000981:diagnostic imaging; D034941:Upper Extremity / Q000000981:diagnostic imaging; D014915:Whole-Body Counting
chemical_list: D002951:Citrates; D019275:Radiopharmaceuticals; D005708:Gallium; C103850:gallium citrate