Buruli's ulcer: three cases diagnosed and treated in France.
The authors report three cases of skin ulcer, called Buruli's ulcer. This is a tropical disease, caused by Mycobacterium ulcerans. The diagnosis is often belated, because the infection is rare in Europe. Diagnosis is based on the clinical aspects, and can be confirmed by a biopsy and a molecular study. A culture is needed to test antibiotics. Treatment is always surgical, including a wide excision of all lesions, and specific oral antibiotics for 6 months.
Journeau
Pierre
P
Paediatric Surgery Department, Le Mans Hospital, Le Mans, France. p.journeau@chu-nancy-fr
Fitoussi
Franck
F
Jehanno
Pascal
P
Padovani
Jean-Paul
JP
Pennecot
Georges-François
GF
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D017291:Clarithromycin / Q000627:therapeutic use; D007560:Cote d'Ivoire / Q000208:ethnology; D005602:France; D006801:Humans; D007866:Leg / Q000382:microbiology* / Q000601:surgery; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000628:therapy; D019911:Mycobacterium ulcerans / Q000302:isolation & purification*; D012293:Rifampin / Q000627:therapeutic use; D018461:Soft Tissue Infections / Q000175:diagnosis* / Q000628:therapy
D000900:Anti-Bacterial Agents; D017291:Clarithromycin; D012293:Rifampin