Stereotactic neurosurgery for movement disorders.
Stereotactic neurosurgery for the treatment of movement disorders focuses primarily on the treatment of Parkinson's disease (PD), essential tremor (ET), and dystonia. The surgical targets in use are the subthalamic nucleus (STN) and the globus pallidus internus (GPi) for PD, GPi for dystonia, and ventralis intermedius (Vim) nucleus of the thalamus for ET. Following target selection, procedures include the generation of lesions or the placement of deep brain stimulating electrodes in the selected target. Additionally, transplantation has been used in the treatment of PD. The indications, outcomes, and risks of the various procedures are reviewed.
Abosch
Aviva
A
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
Lozano
Andres
A
D004421:Dystonia / Q000503:physiopathology / Q000601:surgery; D004599:Electric Stimulation Therapy / Q000295:instrumentation / Q000379:methods; D020329:Essential Tremor / Q000503:physiopathology / Q000601:surgery; D005917:Globus Pallidus / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D016343:Monitoring, Intraoperative; D009069:Movement Disorders / Q000503:physiopathology / Q000601:surgery*; D019635:Neurosurgical Procedures; D010300:Parkinson Disease / Q000503:physiopathology / Q000601:surgery; D018579:Patient Selection; D013238:Stereotaxic Techniques; D020531:Subthalamic Nucleus / Q000503:physiopathology / Q000601:surgery; D013788:Thalamus / Q000503:physiopathology / Q000601:surgery; D016896:Treatment Outcome; D014202:Tremor / Q000503:physiopathology / Q000601:surgery