The effect of propofol (anesthetic and inhibitor of CYP3A4) on serum lidocaine concentrations in smokers and chronic alcohol consumers.
Elmas
T
T
Mavioglu
O
O
Oztekin
S
S
Elar
Z
Z
Guven
H
H
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000378:metabolism*; D000777:Anesthetics / Q000097:blood / Q000494:pharmacology*; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004347:Drug Interactions; D006801:Humans; D007275:Injections, Intravenous; D008012:Lidocaine / Q000097:blood*; D008875:Middle Aged; D015742:Propofol / Q000494:pharmacology*; D012907:Smoking / Q000378:metabolism*
D000777:Anesthetics; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D008012:Lidocaine; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D015742:Propofol