title: Impact of urinary incontinence and overactive bladder on quality of life.
abstract: OBJECTIVE
  To assess the quality of life (QOL) of women with urinary incontinence (UI) or overactive bladder (OB) compared with women without UI.
  
  
  METHODS
  A case-control study conducted in Italy on risk factors for UI and OB. Information on QOL were collected using the SF-12 questionnaire, validated for Italian women.
  
  
  RESULTS
  A total of 1062 cases (258 had stress, 195 urge, 486 mixed UI and 123 OB without incontinence) and 1143 controls were interviewed. QOL, as assessed by the SF-12, was significantly impaired in cases compared with controls (p=0.0001); the mean SF-12 physical health score was 48.3 for controls, but 45.6, 42.0, 44.5 and 40.0 for cases with OB, urge, stress and mixed incontinence, respectively. Women with OB had significantly higher physical health scores than women with urge and mixed UI (p<0.005) (44.6 versus 41.7 and 41.3). Physical and mental health dimensions of cases significantly decreased with increasing severity of symptoms.
  
  
  CONCLUSIONS
  QOL was significantly impaired in women with UI or OB compared to controls. Physical and mental functioning tended to be more impaired in patients than in controls.
authors.affiliation: Istituto di Ricerche Farmacologiche "Mario Negri", Via Eritrea 62, 20157, Milano, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Chiaffarino
authors.forename: Fabio
authors.initials: F
authors.lastname: Parazzini
authors.forename: Maurizio
authors.initials: M
authors.lastname: Lavezzari
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Giambanco
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D016022:Case-Control Studies; D005260:Female; D006304:Health Status; D006801:Humans; D007558:Italy; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence; D014550:Urinary Incontinence, Stress