title: Dual derivatization and GC-MS analysis of phenolic compounds suspected of being xenoestrogens.
abstract: A procedure has been specifically designed to characterize suspect phenolic xenoestrogens in derivatized form by GC-MS. Methyl and trimethylsilyl derivatives of phenolic compounds were sequentially subjected to GC-MS. The mass spectral information derived from the molecular ion allowed the determination of the number of reactive hydroxyl groups and the molecular weight of the parent phenol.
authors.affiliation: Centre for Environmental Research, Brunel University, Uxbridge, Middlesex, United Kingdom. Susan.Grimes@brunel.ac.uk
authors.forename: Susan M
authors.initials: SM
authors.lastname: Grimes
authors.forename: Brian B
authors.initials: BB
authors.lastname: Wheals
authors.forename: Lina K
authors.initials: LK
authors.lastname: Mehta
authors.forename: Akiko
authors.initials: A
authors.lastname: Yokomi
mesh_terms: D004967:Estrogens / Q000032:analysis* / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D015262:Xenobiotics / Q000032:analysis / Q000737:chemistry
chemical_list: D004967:Estrogens; D010636:Phenols; D015262:Xenobiotics