title: Mycosporine-glutamicol-glucoside: a natural UV-absorbing secondary metabolite of rock-inhabiting microcolonial fungi.
abstract: Microcolonial ascomycetes are known to inhabit bare rock surfaces in cold and hot deserts and thus are habitually exposed to high levels of solar radiation. Several of these stress-tolerant fungal isolates, cultivated in the laboratory under daylight illumination, were studied for the presence of effective UV-radiation protection substances. Liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS) analyses allowed for efficient separation and structure clarification of two mycosporines. It was demonstrated that both mycosporine-glutamicol-glucoside and mycosporine-glutaminol-glucoside are natural and constitutive secondary metabolites of microcolonial fungi. The function and relation of these substances in the fungal cell are discussed.
authors.affiliation: Institute of Chemistry and Biology of the Marine Environment (ICBM), Carl von Ossietzky University Oldenburg, PO Box 2503, 26111 Oldenburg, Germany. marc.volkmann@uni-oldenburg.de
authors.forename: Marc
authors.initials: M
authors.lastname: Volkmann
authors.forename: Kenia
authors.initials: K
authors.lastname: Whitehead
authors.forename: Heike
authors.initials: H
authors.lastname: Rütters
authors.forename: Jürgen
authors.initials: J
authors.lastname: Rullkötter
authors.forename: Anna A
authors.initials: AA
authors.lastname: Gorbushina
mesh_terms: D001203:Ascomycota / Q000737:chemistry* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003511:Cyclohexanols / Q000737:chemistry* / Q000378:metabolism; D005960:Glucosides / Q000737:chemistry* / Q000378:metabolism; D006027:Glycosides / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D013473:Sunscreening Agents / Q000737:chemistry* / Q000378:metabolism; D014466:Ultraviolet Rays
chemical_list: D003511:Cyclohexanols; D005960:Glucosides; D006027:Glycosides; D013473:Sunscreening Agents; C474430:mycosporine-glutamicol-glucoside