Management of paracetamol poisoning.
Paracetamol is the most common substance involved in self-poisoning in the UK. The main advances made over the past five years in the management of early paracetamol poisoning, identification of risk factors for paracetamol poisoning, understanding of the mechanisms and management of late paracetamol poisoning and issues concerning the prevention of paracetamol poisoning are discussed.
Dargan
Paul I
PI
National Poisons Information Service, Guy's & St Thomas' NHS Trust, Avonley Road, London SE14 5ER, UK. paul.dargan@gstt.sthames.nhs.uk
Jones
Alison L
AL
D000082:Acetaminophen / Q000494:pharmacology / Q000506:poisoning*; D000111:Acetylcysteine / Q000009:adverse effects / Q000627:therapeutic use; D000437:Alcoholism / Q000150:complications; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology / Q000506:poisoning*; D000931:Antidotes / Q000009:adverse effects / Q000627:therapeutic use; D002626:Chemistry, Pharmaceutical; D062787:Drug Overdose; D004349:Drug Packaging; D006801:Humans; D011041:Poisoning / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy; D012307:Risk Factors; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology
D018712:Analgesics, Non-Narcotic; D000931:Antidotes; D000082:Acetaminophen; D000111:Acetylcysteine