title: Recalcitrant atopic dermatitis due to allergy to Compositae.
abstract: Atopic dermatitis is often complicated by allergic contact dermatitis, although patch testing may reveal positive reactions of uncertain relevance. We report a case of a 35-year-old woman with recalcitrant atopic dermatitis, with a positive patch-test reaction to Compositae mix (CM). Initially, sensitization appeared to be of past relevance only, due to use of calendula. However, it turned out that she followed a self-devised diet consisting largely of food products of the Compositae family. On excluding these food products her skin condition improved quickly. This case report underscores the difficulty in determining the relevance of positive patch tests, and shows that thorough analysis of positive patch tests, by both patient and physician, may reveal unexpected or less common sources of contact allergens.
authors.affiliation: Department of Dermatology, Leiden University Medical Center, the Netherlands. mwintzen@knmg.nl
authors.forename: M
authors.initials: M
authors.lastname: Wintzen
authors.forename: A S
authors.initials: AS
authors.lastname: Donker
authors.forename: E J
authors.initials: EJ
authors.lastname: van Zuuren
mesh_terms: D000328:Adult; D000485:Allergens; D019659:Asteraceae / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D003876:Dermatitis, Atopic / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010328:Patch Tests; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D000485:Allergens