title: Clinical application of a new bioresorbable guided tissue regeneration device: case reports.
abstract: Bioresorbable barriers have been recently introduced in clinical practice for guided tissue regeneration therapy. One of these is the Guidor matrix barrier which is made of amorphous polylactic acid softened with a citric acid ester to increase malleability and facilitate clinical handling. The advantages of the bioresorbable barrier include: the elimination of second surgery; better handling and adaptation around the tooth and over the bone; and integration of the connective tissue of the flap with the barrier preventing epithelial migration, gingival recession, and pocket formation. In the case of matrix exposure the material disappears within 6 to 8 weeks. The purpose of this report is to present the clinical application of the Guidor matrix barrier in the treatment of two- or three-wall intrabony defects that were followed up for more than 1 year. The evaluation included soft tissue changes using clinical parameters and hard tissue changes using nonstandardized digital subtraction radiography. In the authors' opinion, the incorporation of a bioresorbable barrier in guided tissue regeneration therapy represents a significant improvement in the treatment of intrabony defects.
authors.affiliation: Dental School, University of Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Parashis
authors.forename: A
authors.initials: A
authors.lastname: Andronikaki-Faldami
authors.forename: K
authors.initials: K
authors.lastname: Tsiklakis
authors.forename: P
authors.initials: P
authors.lastname: van der Stelt
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D016301:Alveolar Bone Loss / Q000145:classification / Q000601:surgery; D000539:Alveolar Process / Q000000981:diagnostic imaging; D001672:Biocompatible Materials / Q000737:chemistry / Q000627:therapeutic use; D002951:Citrates / Q000737:chemistry / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000145:classification / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D010012:Osteogenesis / Q000502:physiology; D017622:Periodontal Attachment Loss / Q000145:classification / Q000601:surgery; D010514:Periodontal Pocket / Q000145:classification / Q000601:surgery; D010518:Periodontitis / Q000601:surgery; D018583:Pliability; D011091:Polyesters / Q000737:chemistry / Q000627:therapeutic use; D011856:Radiographic Image Enhancement; D013382:Subtraction Technique; D013524:Surgical Flaps / Q000473:pathology
chemical_list: D001672:Biocompatible Materials; D002951:Citrates; C105021:Guidor; D008567:Membranes, Artificial; D011091:Polyesters