Thalidomide: current therapeutic uses and management of its toxicities.
Thalidomide currently is used to treat relapsed and refractory multiple myeloma. The drug also is being actively investigated in patients newly diagnosed with multiple myeloma. The therapeutic applications of thalidomide are expected to grow as clinical trials document its activity in treating other neoplastic disorders and diseases. Healthcare providers need to be well informed of its toxicities and able to identify their signs and symptoms immediately. They must have adequate knowledge about thalidomide administration and provide comprehensive patient education regarding thalidomide and its toxicities to ensure patient safety and compliance.
Tariman
Joseph D
JD
jtariman@nmff.org
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D020533:Angiogenesis Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D003248:Constipation / Q000139:chemically induced; D006801:Humans; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D013792:Thalidomide / Q000009:adverse effects* / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000139:chemically induced
D020533:Angiogenesis Inhibitors; D013792:Thalidomide