Some aspects of the stability of ion current in a matrix-assisted laser desorption/ionization source.
The effect of laser exposure (the number of laser shots) on the stability of production of matrix (gentisic acid, sinapinic acid, nicotinic acid and benzoic acid) and biomolecule (insulin and cytochrome-c) ions is presented. Two methods of sample preparation, dried-droplet and pressure, were examined. In the case of pressure preparation, the dry powder sample was pressed mechanically with a pressure of 30 MPa. The best results were obtained for the pressure method and gentisic acid as matrix.
Ptasińska
Sylwia
S
Institute of Physics, Maria Curie-Skłodowska University, 20-031 Lublin, Poland.
Michalak
Leszek
L
Smolira
Marcin
M
D019817:Benzoic Acid / Q000737:chemistry; D003373:Coumaric Acids / Q000737:chemistry; D003574:Cytochrome c Group / Q000737:chemistry; D005841:Gentisates; D062385:Hydroxybenzoates / Q000737:chemistry; D007328:Insulin / Q000737:chemistry; D009525:Niacin / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
D003373:Coumaric Acids; D003574:Cytochrome c Group; D005841:Gentisates; D062385:Hydroxybenzoates; D007328:Insulin; D010455:Peptides; D009525:Niacin; C073734:sinapinic acid; D019817:Benzoic Acid; C010925:2,5-dihydroxybenzoic acid