title: [Brachyurins--serine collagenolytic enzymes from crabs].
abstract: The properties of brachyurins, proteolytic enzymes belonging to a new subfamily of chymotrypsin-like proteases, are considered. These enzymes, found in various species of crustacean, exhibit mixed substrate specificity and a marked collagenolytic activity. The enzymatic and physicochemical properties of brachyurins I and their primary and spatial structures are discussed in detail. A separate chapter is devoted to the preparations of collagenases from the hepatopancreas of king crab: their action on the damaged skin and use in medicine.
authors.affiliation: Chemical Faculty, Moscow State University, Vorob'evy gory, GSP Moscow, 119899 Russia. laboratoriahps@hotmail.com
authors.forename: G N
authors.initials: GN
authors.lastname: Rudenskaia
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003386:Brachyura / Q000201:enzymology*; D002918:Chymotrypsin / Q000737:chemistry / Q000378:metabolism; D003094:Collagen / Q000737:chemistry / Q000378:metabolism*; D017364:Collagenases / Q000378:metabolism; D004064:Digestive System / Q000201:enzymology; D008969:Molecular Sequence Data; D012697:Serine Endopeptidases / Q000737:chemistry* / Q000378:metabolism* / Q000627:therapeutic use; D012871:Skin Diseases / Q000188:drug therapy; D013379:Substrate Specificity; D014357:Trypsin / Q000737:chemistry / Q000378:metabolism
chemical_list: D003094:Collagen; D012697:Serine Endopeptidases; D002918:Chymotrypsin; D014357:Trypsin; D017364:Collagenases
vernacular_title: Brakhiuriny--serinovye kollagenoliticheskie fermenty krabov.