Campylobacter jejuni O:19 serotype-associated Guillain-Barré syndrome in a child: the first case reported from Greece.
We present a case of Guillain-Barré syndrome (GBS) following Campylobacter jejuni HS serotype O:19 infection in a child. Antibodies against C. jejuni and autoantibodies to the peripheral nerve gangliosides GM1 were positive, a pattern correlating well with the existence of an inflammatory neuropathy like GBS. The patient shared the HLA-B35 and HLA-DR8 antigens, which have been found to be increased in GBS patients with previous C. jejuni infection. As this is the first diagnosed C. jejuni-associated GBS case reported from Greece, further clinical and epidemiologic investigations are warranted.
Chatzipanagiotou
S
S
Department of Clinical Microbiology, Aeginition Hospital, Medical School of Athens, Vass. Sophias av. 72-4, 115 28 Athens, Greece. chatlouk@hotmail.com
Kilidireas
K
K
Trimis
G
G
Nicolaou
C
C
Anagnostouli
M
M
Athanassaki
C
C
Giannoulia
A
A
Legakis
N
N
Youroukos
S
S
D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D002169:Campylobacter Infections / Q000150:complications* / Q000188:drug therapy; D016123:Campylobacter jejuni / Q000254:growth & development*; D002648:Child; D004917:Erythromycin / Q000627:therapeutic use; D006115:Greece; D020275:Guillain-Barre Syndrome / Q000188:drug therapy / Q000382:microbiology*; D015797:HLA-B35 Antigen / Q000097:blood; D006684:HLA-DR Antigens / Q000097:blood; D059810:HLA-DR Serological Subtypes; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D008297:Male; D019081:O Antigens / Q000097:blood
D000907:Antibodies, Bacterial; D001323:Autoantibodies; D015797:HLA-B35 Antigen; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C041559:HLA-DR8 antigen; D007136:Immunoglobulins; D019081:O Antigens; D004917:Erythromycin