title: [Sleepy drivers have a high frequency of traffic accidents related to respiratory effort-related arousals].
abstract: BACKGROUND
  Respiratory effort-related arousals (RERA) are secondary to subtle obstructions of the upper airway during sleep and can appear in the absence of a predominance of apneas and hypopneas, causing excessive daytime sleepiness. Analyzing the possible consequences of these new respiratory events is of increasing interest. Habitually sleepy drivers are at high risk of having traffic accidents related to sleep disorders (apneas, hypopneas and RERA).
  
  
  OBJECTIVE
  The aim of this study was to determine whether excess RERA alone is an independent risk factor among sleepy drivers.
  
  
  METHODS
  We studied 40 habitually sleepy drivers and 23 age- and sex-matched controls selected from a sample of 4,002 automobile drivers. We surveyed sleep habits, daytime sleepiness and traffic accidents. Sleep studies of esophageal pressure were performed.
  
  
  RESULTS
  The sleepy drivers with apneas (apnea/hypopnea index > 10) had a higher 5-year accident rate (0.33 0.50) than did control drivers (0.004 0.21; p < 0.05). However, a high RERA index, but not sleep apnea, was an independent risk factor among the habitually sleepy drivers. The adjusted odds ratio (OR) for a RERA index > or = 10 was 7.6 (confidence interval [CI], 1.2 to 48); for a RERA index > or = 15, the OR was 17 (CI 1.5 to 91).
  
  
  CONCLUSIONS
  The high risk of traffic accidents among sleepy drivers is mainly determined by the presence of RERA rather than the presence of apneas and hypopneas. These findings verify the importance of identifying RERA in routine sleep laboratory studies.
authors.affiliation: Sección de Neumología. Hospital San Pedro de Alcántara. Cáceres. Spain. fmasa@separ.es
authors.forename: J F
authors.initials: JF
authors.lastname: Masa Jiménez
authors.forename: M
authors.initials: M
authors.lastname: Rubio González
authors.forename: L J
authors.initials: LJ
authors.lastname: Findley
authors.forename: J A
authors.initials: JA
authors.lastname: Riesco Miranda
authors.forename: A
authors.initials: A
authors.lastname: Sojo González
authors.forename: C
authors.initials: C
authors.lastname: Disdier Vicente
mesh_terms: D000063:Accidents, Traffic / Q000706:statistics & numerical data*; D000328:Adult; D001334:Automobile Driving; D006970:Disorders of Excessive Somnolence / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000175:diagnosis
vernacular_title: Los conductores somnolientos tienen alta frecuencia de accidentes de tráfico asociados a exceso de RERA.