title: Leber congenital amaurosis associated with optic disk neovascularization and vitreous hemorrhage.
abstract: OBJECTIVE
  To report an unusual case of optic disk neovascularization and vitreous hemorrhage associated with Leber congenital amaurosis (LCA).
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 16-year-old Caucasian girl with a history of LCA presented with decreased vision in her left eye, diffuse retinal pigmentary abnormalities characteristic of LCA, and hemorrhage over the left optic disk and macula. Six months of follow-up revealed optic disk neovascularization. A small amount of neovascularization was noted in the right eye at 6 months.
  
  
  RESULTS
  An extensive systemic evaluation indicated no other cause for the neovascularization. Panretinal photocoagulation was performed in both eyes, and subsequently the neovascularization regressed.
  
  
  CONCLUSIONS
  Leber congenital amaurosis like retinitis pigmentosa, can rarely be associated with neovascularization of the disk, which is amenable to treatment with peripheral photocoagulation if it does not spontaneously regress.
authors.affiliation: Retina Service, Indiana University, Indianapolis, USA.
authors.forename: Daryl
authors.initials: D
authors.lastname: Kurz
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Ciulla
mesh_terms: D000293:Adolescent; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D017075:Laser Coagulation; D029242:Optic Atrophy, Hereditary, Leber / Q000150:complications* / Q000175:diagnosis; D009898:Optic Disk / Q000098:blood supply*; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D014823:Vitreous Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery