title: [Mechanisms of activation of pathogenic bacteria in the host organism].
abstract: A minireview of the data of literature on the interaction of bacteria with cytokins and the stimulation of the growth of pathogenic bacteria by some cytokins is presented. The addition of tumor necrosis factor-alpha into the culture medium has been shown to stimulate the growth of Salmonella virulent and avirulent strains 4-fold and 2-fold respectively. This cytokin has also been shown to produce a stimulating effect on the process of the in vitro and in vivo recultivation of noncultivating forms of virulent and avirulent strains.
authors.affiliation: Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Romanova
authors.forename: R Kh
authors.initials: RKh
authors.lastname: Boshnakov
authors.forename: T V
authors.initials: TV
authors.lastname: Baskakova
authors.forename: A L
authors.initials: AL
authors.lastname: Gintsburg
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism / Q000494:pharmacology; D006790:Host-Parasite Interactions / Q000187:drug effects / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007700:Kinetics; D012480:Salmonella Infections / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D012486:Salmonella typhimurium / Q000472:pathogenicity / Q000502:physiology*; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism; D015534:Trans-Activators / Q000235:genetics* / Q000276:immunology; D015533:Transcriptional Activation; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*; D014774:Virulence
chemical_list: D016207:Cytokines; D015534:Trans-Activators; D014409:Tumor Necrosis Factor-alpha
vernacular_title: Mekhanizmy aktivatsii patogennykh bakteriĭ v organizme khoziaina.