[Research advances on mammalian circadian clock-related genes].
Circadian rhythms,generated by endogenous biological clocks,regulate physiological activities autonomously. It is one of the focuses in life science in recent years. The researches on the mechanism of mammalian circadian clock have been developed at the molecular level. Some clock-related genes are cloned and identified in succession. The core mechanism for the master circadian clock consists of interaction between the positive and negative transcription and translation feedback loops. The peripheral tissues cultured in vitro exhibit circadian rhythms as well. These give clues to further research.
Wei
Fang
F
Department of Biomedical Engineering, West China Center of Medical Sciences, Sichuan University, Chengdu, PR China.
Wang
Zheng-Rong
ZR
D000818:Animals; D001683:Biological Clocks / Q000235:genetics*; D002940:Circadian Rhythm / Q000235:genetics*; D008322:Mammals; D020419:Photoreceptor Cells, Vertebrate / Q000502:physiology*