Propofol--a safe and effective sedative for endoscopy.
BACKGROUND
Propofol has recently been reported to be a safe sedative for endoscopy.


METHODS
One hundred consecutive patients more than 18 years of age undergoing an endoscopic procedure were included in the study. The risk of sedation was calculated using the American Society of Anesthesiology risk class. Pregnant women, patients opting to undergo endoscopy without sedation, and those allergic to any sedative, eggs or soyabeans were excluded. A trained nurse administered propofol under the supervision of an anesthesiologist. Vital parameters, including oxygen saturation, were measured before and during the procedure. Time taken for full sedation, quantity of propofol used, duration of the procedure, time taken for recovery from sedation, and any complication during or after anesthesia were recorded. The patients scored quality of sedation, perception of pain and any memory of the procedure.


RESULTS
Eighty-four patients were in ASA risk class I and II and the remaining 16 were in a higher ASA risk class. There was no difference in vital sign measurements during the endoscopic procedures as compared to baseline values. None of the patients had any complication. More than 90% of patients did not report any pain and had complete amnesia for the procedure.


CONCLUSIONS
Propofol is a safe and effective sedative for endoscopic procedures.
Khanna
Sudeep
S
Department of Gastroenterology, Pushpawati Singhania Research Institute for Liver, Renal and Digestive Diseases, New Delhi 110 017. khannasudeep@hotmail.com
Tobin
Raj
R
Khare
Sanjay
S
Vij
Jagdish
J
Kumar
Arun
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008875:Middle Aged; D015742:Propofol; D011446:Prospective Studies
D006993:Hypnotics and Sedatives; D015742:Propofol