[Analysis of bacteriological tests of children with decreased serum immunoglobulin IgA levels].
Results of 142 children with decreased serum immunoglobulin IgA compared with the reference values for age, and 73 reached normal age levels for serum immunoglobulin (control group), up 6 months to 14 years of age with various clinical symptoms, admitted to hospital between 1999-2000, were analysed. The patients were divided into three groups: group I--children with decreased serum immunoglobulin IgA levels (86 patients), group II--children with hypogammaglobulinaemia IgA and IgG compared with the reference values for age (56 patients), group III--children reaching normal levels of serum immunoglobulin for age (73 patients)--control group. Staphylococcus aureus was found most frequently among pathogenic strains in groups I and II in comparison to the control group. In urine, Enterococcus faecalis strains were observed more often in the first and in the second group than in the control group. All patients in our three groups showed high per cent of Candida albicans in biological material from the pharynx and faeces. We associated this with treatment of recurrent infections in children, using many antibiotics. In conclusion, our results have demonstrated that low serum IgA and IgG concentrations in children are favourable for colonisation with pathogenic microorganisms.
Basiewicz-Worsztynowicz
Barbara
B
Katedra Propedeutyki Pediatrii i Klinika Immunologii Wieku Rozwojowego, Akademii Medycznej we Wrocławiu.
Polańska
Bozena
B
Karnas-Kalemba
Wiesława
W
Nienartowicz
Barbara
B
Lewczyk
Ewa
E
Jankowski
Adam
A
Gorczyca
Daiva
D
Bajda
Barbara
B
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000276:immunology; D016908:Gram-Positive Bacterial Infections / Q000276:immunology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology; D017098:IgA Deficiency / Q000276:immunology*; D007070:Immunoglobulin A / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D008297:Male; D012016:Reference Values; D013997:Time Factors
D000900:Anti-Bacterial Agents; D007070:Immunoglobulin A; D007074:Immunoglobulin G
Analiza wyników wybrancych badań bakteriologicznych u dzieci z obnizonym stezeniem surowiczego IgA.