title: [Use of antibiotics in otorhinolaryngologic practice].
abstract: BACKGROUND
  This study investigated utilization of antibacterial agents at the Ear, Nose and Throat Department of the Outpatient Service of the Health Center Novi Sad-Liman and at the Ear, Nose and Throat Clinic of the Clinical Center Novi Sad, in the period February-March 2001.
  
  
  METHODS
  All antibacterial agents were classified as group J, regarding Anatomic-Therapeutic-Chemical Classification. Data on drug utilization were presented in Defined Daily Doses (DDD). Patients who were under observation were all treated with antibiotics.
  
  
  RESULTS
  In regard to prescribed treatment in the Ear, Nose and Throat Department of the Outpatient Service of the Health Center Novi Sad-Liman, most outpatients were treated with macrolide antibiotics--in 26.21%; combination of penicillin and beta-lactamase inhibitors in 20.83% and pyranosides in 16.12%. At the Ear, Nose and Throat Clinic of the Clinical Center Novi Sad, macrolides and lincosamines were most frequently used--in 20.46%; cephalosporins in 19.87% and penicillins susceptible to beta-lactamase in 18.85%. It is extremely positive and in agreement with current pharmacotherapeutic principles that in both institutions peroral ampicillins have not been prescribed. Aminoglycosides have been prescribed in less than 1% of patients of the Ear, Nose and Throat Department of the Outpatient Service of the Health Center Novi Sad-Liman, whereas they were much more frequently prescribed at the Ear, Nose and Throat Clinic of the Clinical Center Novi Sad--in 11.25%. Although there is a positive postantibiotic effect in regard to these antibiotics and it is recommended to use them once a day, in both examined institutions aminoglycosides were given twice a day. In regard to bacterial identification it was done in 80.76% of patients of the Ear, Nose and Throat Department of the Outpatient Service of the Health Center Novi Sad-Liman, while in the Ear, Nose and Throat Clinic of the Clinical Center Novi Sad it was done only in 32.42%.
  
  
  CONCLUSIONS
  Although treatment performed on empirical basis and clinical findings is usually correct, a greater percentage of antibiotic prescriptions should be confirmed by antibiograms providing optimal therapy and decreased degree of resistance.
authors.affiliation: Klinika za infektivne bolesti, 21000 Novi Sad, Hajduk Veljkova 1-3. stefanns@eunet.yu
authors.forename: Sandra
authors.initials: S
authors.lastname: Stefan-Mikić
authors.forename: Ana
authors.initials: A
authors.lastname: Sabo
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Jovancević
authors.forename: Jasna
authors.initials: J
authors.lastname: Jovićević
authors.forename: Marija
authors.initials: M
authors.lastname: Vasović
authors.forename: Vida
authors.initials: V
authors.lastname: Jakovljević
mesh_terms: D000554:Ambulatory Care Facilities; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004363:Drug Utilization; D006801:Humans; D010038:Otorhinolaryngologic Diseases / Q000188:drug therapy*; D015022:Yugoslavia
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Upotreba antibiotika u otorinolaringoloskoj praksi.