An appraisal of post-irradiation metabolic changes in toad liver (Bufo melanostictus).
Whole body 60Co gamma irradiation of B . melanostictus with two sublethal doses of 3.5 and 7 Gy resulted in a significant increase (P < 0.001) in total lipid (hyperlipidemia), cholesterol content (hypercholesterolemia) and total free amino acid content, and significant decrease (P < 0.001) in total protein content in the liver tissues on post-irradiation day (PID) 1, 5 and 10 as compared to controls. The ratio of total lipid to cholesterol showed a gradual declining trend by PID-10 in the treated groups as compared to controls. However, it was more pronounced in the 7 Gy treated group. An observation on the ratio of total protein to total free amino acid content also showed a similar declining trend by PID-10 in both the treated groups as compared to controls.
Mishra
J
J
School of Life Sciences, Jyoti Vihar, Sambalpur University, Burla 768 019, India.
Mittra
A
A
D000818:Animals; D002025:Bufonidae; D004307:Dose-Response Relationship, Radiation; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*