title: [Non post-operative spondylodiskitis. Our experience during the period 1990-2001].
abstract: Aim of the study was to evaluate the prevalence and characteristics of non operative spondylodiskitis (SD) in our geographic area.
  
  
  METHODS
  We evaluated retrospectively epidemiological, clinical, laboratory and radiological features of patients with non operative SD observed between 1990 and 2001 in our department of the "D. Cotugno" hospital - Naples.
  
  
  RESULTS
  Eighteen patients with diagnosis of SD were evaluated. Etiologic agent was identified in 17 patients: M. tuberculosis in 5, brucella spp. in 4 and pyogenic bacteria in 8. Ten patients had underlying diseases or risk factors (4 diabetes mellitus, 3 arthrosis, 1 CRF, 1 IVDA and 2 previous back trauma). Symptoms preceded observation between 2 days and 12 months (median value 15 days). Seventeen patients presented fever, 13 back pain, 6 meningitis, 3 were comatous and 2 had severe sepsis. Ten patients showed high white blood cells count with granulocyte prevalence. Eritrosedimentation rate or C reactive protein were elevated in all patients. Diagnosis was confirmed in 8 patients only with radiographs of the spine, while 3 needed a CT and 11 a RMN imaging. Antimicrobial therapy was perfomed for at least 6 months in patients with brucellosis, 12 months in patients with tuberculosis and 2 months in patients with pyogenic SD. Persistent neurological deficit were observed in 2 patients.
  
  
  CONCLUSIONS
  Neurological deficit may be avoid in patients affected by SD only with a carefull diagnosis and an accurate antibiotic therapy.
authors.affiliation: Centro Neuropatie Infettive Ospedale "D. Cotugno" Napoli, Italy.
authors.forename: Francesco Saverio
authors.initials: FS
authors.lastname: Faella
authors.forename: Marco
authors.initials: M
authors.lastname: Rossi
authors.forename: Pasquale
authors.initials: P
authors.lastname: Pagliano
authors.forename: Vittorio
authors.initials: V
authors.lastname: Attanasio
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Briante
authors.forename: Ugo
authors.initials: U
authors.lastname: Fusco
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mascarella
authors.forename: Francesco
authors.initials: F
authors.lastname: Scarano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D003131:Combined Modality Therapy; D015299:Discitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000601:surgery; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Spondilodisciti non chirurgiche. Casistica degli anni 1990-2001.