title: High prevalence of PER-1 extended-spectrum beta-lactamase-producing Acinetobacter spp. in Korea.
abstract: PER-1, an extended-spectrum beta-lactamase, has been reported only in Europe. We detected PER-1 in 53 of 97 acinetobacters in Korea, mainly in the sputum of intensive care unit patients. Pulsed-field gel electrophoresis analysis suggested that clonal spread had occurred. Only PCR reliably detected PER-1 producers. PER-1 producers may also exist in other Asian countries.
authors.affiliation: Department of Laboratory Medicine, Research Institute of Bacterial Resistance. BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Dongeun
authors.initials: D
authors.lastname: Yong
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Sinyoung
authors.initials: S
authors.lastname: Kim
authors.forename: Youngsik
authors.initials: Y
authors.lastname: Lim
authors.forename: Jong Hwa
authors.initials: JH
authors.lastname: Yum
authors.forename: Kyungwon
authors.initials: K
authors.lastname: Lee
authors.forename: Yunsop
authors.initials: Y
authors.lastname: Chong
authors.forename: Adolf
authors.initials: A
authors.lastname: Bauernfeind
mesh_terms: D000150:Acinetobacter / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D007723:Korea; D011550:Pseudomonas aeruginosa / Q000201:enzymology; D001618:beta-Lactamases / Q000032:analysis* / Q000096:biosynthesis
chemical_list: C108863:beta-lactamase PER-1; D001618:beta-Lactamases