(Z)-sarcodictyin A, a new highly cytotoxic diterpenoid from the soft coral Bellonella albiflora.
A new cytotoxic diterpene, (Z)-sarcodictyin A, was isolated from the Japanese soft coral Bellonella albiflora.(1) Its structure was elucidated on the basis of 1D and 2D NMR analysis and chemical degradation. (Z)-Sarcodictyin A showed strong cytotoxicity against HeLa human cervix cells.
Nakao
Yoichi
Y
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshida
Satoru
S
Matsunaga
Shigeki
S
Fusetani
Nobuhiro
N
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003063:Cnidaria / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D007564:Japan; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism; D014407:Tumor Cells, Cultured / Q000187:drug effects; D002583:Uterine Cervical Neoplasms
D000470:Alkaloids; D000970:Antineoplastic Agents; D004224:Diterpenes; C109552:sarcodictyin A