title: Pulmonary inflammatory pseudotumor with rapid growth and serum carcinoembryonic antigen elevation.
abstract: Inflammatory pseudotumors consist of chronic inflammatory cells, predominantly plasma cells. We report a rare case of pulmonary inflammatory pseudotumor associated with rapid growth and elevated serum carcinoembryonic antigen (CEA). A 75-year-old man referred for bloody sputum was found in chest computed tomography (CT) to have a round circumscribed tumor with a cavity located in the periphery of the right lower pulmonary lobe. Cytological examination of a biopsy specimen obtained by CT-guided transthoracic fine needle aspiration showed no malignancy. Two months later, the tumor had noticeably grown, accompanied by a notable rise in serum CEA. We conducted right lower pulmonary lobectomy with regional lymph node dissection, since malignancy could not be ruled out by frozen-section examination. Histological examination of the resected specimen showed an inflammatory pseudotumor with CEA production.
authors.affiliation: Department of Respiratory Disease, Kagawa Prefectural Cancer Detection Center, Takamatsu, Japan.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Misao
authors.forename: Katashi
authors.initials: K
authors.lastname: Satoh
authors.forename: Hideharu
authors.initials: H
authors.lastname: Nakano
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood*; D006801:Humans; D008297:Male; D016726:Plasma Cell Granuloma, Pulmonary / Q000097:blood / Q000473:pathology*
chemical_list: D002272:Carcinoembryonic Antigen