[Skin test reactivity to seven aeroallergens in a Sousse area population sample].
BACKGROUND
Allergy skin tests are an important tool in the diagnosis of allergy diseases. They are useful in epidemiologic studies.


OBJECTIVE
The aim of our study is to estimate the prevalence of the skin sensitivity in a sample of unselected population and to study the relationship between skin test reactivity and clinical manifestations.


METHODS
During 9 months, we undertake skin prick-test in 500 subjects. Our population was recruited in the blood sample room of the biochemistry laboratory of the University Hospital of Sousse. Seven aeroallergen was tested: Dermatophagoïdes pteronyssinus (DPT), Dermatophagoïdes farinae (DF), Pollens of Graminees, Olive-tree, Partetaure, Cockroach and Candidine. A positive and a negative control tests were made.


RESULTS
34% of the population was sensitized to one or more aeroallergens. In the litterature this prevalence vary from 9 to 55.5% according to the methodology applied. In our study the skin reactivity does not change with sex (p = 0.26) but was high in subjects aged between 15 and 35 years. 21.8% were sensitized to house dust mites (DPT, DF) and 18.2% to pollens (Olive-tree, Graminees, Parietaire). Skin reactivity was more common when subjects had personal atopic history (p < 0.003) and/or had actual allergic symptoms particularyrhinitis and asthma (p < 0.006).


CONCLUSIONS
Skin reactivity to common aeroallergens is frequent in the general population, particularly in symptomatic subjects affected by rhinitis and/or allergic asthma. This skin sensitization is the result of genetic and environmental interaction, but skin sensitization does not mean allergy.
Benzarti
M
M
Mezghani
S
S
Jarray
M
M
Garrouche
A
A
Khirouni
S
S
Klabi
N
N
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens / Q000009:adverse effects* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003877:Dermatitis, Contact / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D014416:Tunisia / Q000453:epidemiology
D000485:Allergens
Sensibilisation cutanee aux pneumallergenes courants dans une population generale de la region de Sousse.