title: Functional perfusion imaging using continuous arterial spin labeling with separate labeling and imaging coils at 3 T.
abstract: Functional perfusion imaging with a separate labeling coil located above the common carotid artery was demonstrated in human volunteers at 3 T. A helmet resonator and a spin-echo echo-planar imaging (EPI) sequence were used for imaging, and a circular surface coil of 6 cm i.d. was employed for labeling. The subjects performed a finger-tapping task. Signal differences between the condition of finger tapping and the resting state were between -0.5% and -1.1 % among the subjects. The imaging protocol included a long post-label delay (PLD) to reduce transit time effects. Labeling was applied for all repetitions of the functional run to reduce the sampling interval.
authors.affiliation: Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany. mildner@cns.mpg.de
authors.forename: Toralf
authors.initials: T
authors.lastname: Mildner
authors.forename: Robert
authors.initials: R
authors.lastname: Trampel
authors.forename: Harald E
authors.initials: HE
authors.lastname: Möller
authors.forename: Andreas
authors.initials: A
authors.lastname: Schäfer
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Wiggins
authors.forename: David G
authors.initials: DG
authors.lastname: Norris
mesh_terms: D000328:Adult; D017536:Carotid Artery, Common / Q000502:physiology; D017352:Echo-Planar Imaging; D005385:Fingers / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D010477:Perfusion / Q000295:instrumentation; D013113:Spin Labels
chemical_list: D013113:Spin Labels