Two flavone C-glycosides from the style of Zea mays with glycation inhibitory activity.
A new flavone C-glycoside, chrysoeriol 6-C-beta-boivinopyranosyl-7-O-beta-glucopyranoside (1), and a known flavone C-glycoside (2) were isolated from the style of Zea mays. Each compound contains the rare sugar boivinose. These flavones exhibited glycation inhibitory activity similar to that of aminoguanidine, a known glycation inhibitor.
Suzuki
Ryuichiro
R
Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose-shi, Tokyo 204-8588, Japan.
Okada
Yoshihito
Y
Okuyama
Toru
T
D047309:Flavones; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006031:Glycosylation / Q000187:drug effects*; D006146:Guanidines / Q000494:pharmacology; D007564:Japan; D008519:Medicine, Traditional; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D003313:Zea mays / Q000737:chemistry*
D047309:Flavones; D005419:Flavonoids; D006027:Glycosides; D006146:Guanidines; C477588:chrysoeriol 6-C-beta-L-boivinopyranoside; C477587:chrysoeriol 6-C-beta-boivinopyranosyl-7-O-beta-glucopyranoside; C043562:flavone; C004479:pimagedine