title: [Pathology of implants].
abstract: Progress in the surgery of implants and biomaterials can be accomplished by: 1. Painstakingly analysing and registering of defaulting implants after explantation within a "National Registry of Implant Pathology". 2. Development of a DNA-microarray named "Implantat/Chronic Wound" in order to discover the differential transcriptional activities of cells brought into contact with different foreign surfaces. 3. Predictive cell-engineering combined with custom-made implant surfaces with the aim of optimal patient care.
authors.affiliation: Institut für Pathologie, Universitätsklinikum, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen.
authors.forename: C
authors.initials: C
authors.lastname: Mittermayer
authors.forename: M
authors.initials: M
authors.lastname: Eblenkamp
authors.forename: H A
authors.initials: HA
authors.lastname: Richter
authors.forename: G
authors.initials: G
authors.lastname: Zwadlo-Klarwasser
authors.forename: R S
authors.initials: RS
authors.lastname: Bhardwaj
authors.forename: B
authors.initials: B
authors.lastname: Klosterhalfen
mesh_terms: D002478:Cells, Cultured / Q000473:pathology; D019544:Equipment Failure Analysis / Q000379:methods*; D005549:Foreign-Body Reaction / Q000473:pathology*; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D011183:Postoperative Complications / Q000473:pathology*; D011474:Prosthesis Design; D012042:Registries
vernacular_title: Pathologie der Implantate.