title: [Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus].
abstract: The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase 50-100-fold.
authors.affiliation: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia. bgg@humgen.siobc.ras.ru
authors.forename: B G
authors.initials: BG
authors.lastname: Gavrilov
authors.forename: G S
authors.initials: GS
authors.lastname: Monastyrskaia
authors.forename: T V
authors.initials: TV
authors.lastname: Velikodvorskaia
authors.forename: O B
authors.initials: OB
authors.lastname: Filiukova
authors.forename: S N
authors.initials: SN
authors.lastname: Konovalova
authors.forename: A A
authors.initials: AA
authors.lastname: Kachko
authors.forename: E V
authors.initials: EV
authors.lastname: Protopopova
authors.forename: L G
authors.initials: LG
authors.lastname: Nikolaev
authors.forename: V B
authors.initials: VB
authors.lastname: Loktev
authors.forename: E D
authors.initials: ED
authors.lastname: Sverdlov
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; D002478:Cells, Cultured; D004669:Encephalitis Viruses, Tick-Borne / Q000378:metabolism* / Q000472:pathogenicity; D005786:Gene Expression Regulation; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods; D007668:Kidney / Q000166:cytology / Q000196:embryology / Q000502:physiology / Q000821:virology*; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000032:analysis; D016601:RNA-Binding Proteins; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014776:Virus Cultivation
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; C484290:IFIT1 protein, human; C484289:IFIT2 protein, human; D011506:Proteins; D012333:RNA, Messenger; D016601:RNA-Binding Proteins
vernacular_title: Pozdniaia aktivatsiia interferonindutsiruemykh genov IFI-54k i IFI-56k pri infektsii kletok linii RH cheloveka virusom kleshchevogo éntsefalita.