title: New evidence of spontaneous cure in human Chagas' disease.
abstract: A new case of spontaneous cure of human Chagas' disease is described in Uruguay. An 87-year-old man who had a typical acute phase of Trypanosoma cruzi infection in 1947 and never received specific treatment against the disease, when examined in 1998 revealed several completely negative parasitological and serological tests, including traditional serology, PCR and flow cytometry. As a whole, such findings fulfill the current criteria to define the cure of Chagas' disease. Clinical data suggest the possibility of a benign evolution of Chagas' disease in this case, but the basic findings (slight cardiac and esophageal impairment) could also be due to the advanced age of the patient.
authors.affiliation: National University, Montevideo, Uruguay.
authors.forename: Sonia S
authors.initials: SS
authors.lastname: Francolino
authors.forename: Antonio Fernandez
authors.initials: AF
authors.lastname: Antunes
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Talice
authors.forename: Rachel
authors.initials: R
authors.lastname: Rosa
authors.forename: Joel
authors.initials: J
authors.lastname: Selanikio
authors.forename: Joffre Marcondes
authors.initials: JM
authors.lastname: de Rezende
authors.forename: Alvaro J
authors.initials: AJ
authors.lastname: Romanha
authors.forename: João Carlos Pinto
authors.initials: JC
authors.lastname: Dias
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014355:Chagas Disease / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012075:Remission, Spontaneous