Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp.
We present the first report of community-acquired human infections with marine mammal-associated Brucella spp. and describe the identification of these strains in two patients with neurobrucellosis and intracerebral granulomas. The identification of these isolates as marine mammal strains was based on omp2a sequence and amplification of the region flanking bp26.
Sohn
Annette H
AH
University of California, San Francisco, San Francisco, California, USA. asohn@itsa.ucsf.edu
Probert
Will S
WS
Glaser
Carol A
CA
Gupta
Nalin
N
Bollen
Andrew W
AW
Wong
Jane D
JD
Grace
Elizabeth M
EM
McDonald
William C
WC
D000293:Adolescent; D000328:Adult; D002002:Brucella / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D002006:Brucellosis / Q000188:drug therapy / Q000503:physiopathology; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000503:physiopathology*; D006099:Granuloma / Q000473:pathology*; D006801:Humans; D008297:Male; D010568:Peru