A novel HLA-DRB1 allele, DRB1*0707.
We report herein the identification of a new HLA-DRB1 allele, DRB1*0707. This new allele was seen in a volunteer bone marrow donor (ID#118069) belonging to the German bone marrow donor registry (DKMS). HLA-DRB1*0707 was detected while performing HLA-DRB1 high resolution typing by sequence based typing. This novel allele differs from DRB1*070101 by a single nucleotide substitution at position 163 (C-->T) in exon 2.
Frison
S
S
Centro Trasfusionale e di Immunologia dei Trapianti, Divisione di Ematologia, Ospedale Maggiore Policlinico IRCCS, Via Francesco Sforza 35, 20122 Milan, Italy.
Poli
F
F
Longhi
E
E
Bianchi
P
P
Baier
D Marc
DM
Scalamogna
M
M
D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains