Lamivudine resistance in human T-cell leukemia virus type 1 may be due to a polymorphism at codon 118 (V-->I) of the reverse transcriptase.
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D019380:Anti-HIV Agents / Q000494:pharmacology*; D003062:Codon; D024882:Drug Resistance, Viral; D015368:Human T-lymphotropic virus 1 / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D019259:Lamivudine / Q000494:pharmacology*; D011110:Polymorphism, Genetic; D012194:RNA-Directed DNA Polymerase / Q000235:genetics*; D018894:Reverse Transcriptase Inhibitors / Q000494:pharmacology*
D019380:Anti-HIV Agents; D003062:Codon; D018894:Reverse Transcriptase Inhibitors; D019259:Lamivudine; D012194:RNA-Directed DNA Polymerase