title: Central nervous system involvement in autoimmune polyglandular syndrome.
abstract: We present a 33 year-old man, admitted because of transient deterioration of visual acuity. Magnetic resonance imaging showed diffuse central nervous system (CNS) demyelination, which largely resolved spontaneously within 4 months. The patient fulfilled the diagnostic criteria of APS type III, having autoimmune thyroiditis and alopecia universalis. In this patient, autoimmune activation against CNS antigens is thought to be the cause of reversible CNS demyelination.
authors.affiliation: Department of Neurology, Medical Faculty of Karadeniz Technical University, Trabzon 61080, Turkey. cavitb@yahoo.com
authors.forename: Cavit
authors.initials: C
authors.lastname: Boz
authors.forename: Sibel
authors.initials: S
authors.lastname: Velioglu
authors.forename: Vildan
authors.initials: V
authors.lastname: Altunayoğlu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozmenoglu
authors.forename: Changir
authors.initials: C
authors.lastname: Erem
mesh_terms: D000328:Adult; D000505:Alopecia; D020278:Demyelinating Autoimmune Diseases, CNS / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications* / Q000473:pathology*; D012075:Remission, Spontaneous; D013577:Syndrome; D013966:Thyroiditis / Q000150:complications* / Q000473:pathology*