Use of denaturing HPLC and a heteroduplex generator to detect the HFE C282Y mutation associated with genetic hemochromatosis.
Fruchon
Séverine
S
Unité de Physiopathologie Cellulaire et Moléculaire, CNRS UPR 2163, CHU Purpan, 31059 Toulouse Cedex 3, France.
Bensaid
Mounia
M
Borot
Nicolas
N
Roth
Marie-Paule
MP
Coppin
Hélène
H
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005838:Genotype; D006432:Hemochromatosis / Q000235:genetics*; D000071020:Hemochromatosis Protein; D020180:Heteroduplex Analysis / Q000379:methods; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D020125:Mutation, Missense; D009691:Nucleic Acid Denaturation; D016133:Polymerase Chain Reaction
C103673:HFE protein, human; D000071020:Hemochromatosis Protein; D015395:Histocompatibility Antigens Class I; D008565:Membrane Proteins