Dual derivatization and GC-MS analysis of phenolic compounds suspected of being xenoestrogens.
A procedure has been specifically designed to characterize suspect phenolic xenoestrogens in derivatized form by GC-MS. Methyl and trimethylsilyl derivatives of phenolic compounds were sequentially subjected to GC-MS. The mass spectral information derived from the molecular ion allowed the determination of the number of reactive hydroxyl groups and the molecular weight of the parent phenol.
Grimes
Susan M
SM
Centre for Environmental Research, Brunel University, Uxbridge, Middlesex, United Kingdom. Susan.Grimes@brunel.ac.uk
Wheals
Brian B
BB
Mehta
Lina K
LK
Yokomi
Akiko
A
D004967:Estrogens / Q000032:analysis* / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D015262:Xenobiotics / Q000032:analysis / Q000737:chemistry
D004967:Estrogens; D010636:Phenols; D015262:Xenobiotics