title: Population study of eight novel Y-chromosome STRs (DYS460, DYS461, GATA-A10, GATA-C4, GATA-H4, DYS434, DYS437, DYS439) in a southeast Iberian population: looking for highly informative Y-chromosome haplotypes.
abstract: The present study analyses 8 recently described tetranucleotide microsatellites (DYS460, DYS461, GATA-A10, GATA-C4, GATA-H4, DYS434, DYS437, DYS439) in southeast Spain and out of a total of 76 individuals 67 showed different haplotypes. Out of the 67 different haplotypes, 63 were present once, 3 were found 2 times, and 1 was found 7 times (9.21%). By combining the allelic states of the present eight Y-chromosome STRs with those previously carried out on the same individuals, highly informative haplotypes could be obtained. The haplotype diversity using the basic set of Y-STRs (DYS19, DYS389-I, DYS389-II, DYS390, DYS391, DYS392, DYS393, DYS385 and DYX156Y) previously analyzed is 0.9844. For the same individuals, this value using the new set of Y-STRs is slightly lower (0.8949), while the haplotype diversity combining the two sets of primers significantly increase to 0.9868. The results obtained in the present work show the usefulness of these microsatellites for individual identification and paternity testing in forensic genetics.
authors.affiliation: Laboratorio de Genética Forense U.D. Medicina Legal, Universidad de Valencia E.G., Spain. mercedes.aler@uv.es
authors.forename: M
authors.initials: M
authors.lastname: Aler
authors.forename: A
authors.initials: A
authors.lastname: Salas
authors.forename: E
authors.initials: E
authors.lastname: Murcia
authors.forename: M
authors.initials: M
authors.lastname: Gisbert-Grifo
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D041322:Chromosomes, Human, Y / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D013030:Spain; D020080:Tandem Repeat Sequences