Synthesis of CDE and BCDE molecular fragments of the limonoids havanensin and azadiradione.
A new approach to the synthesis of CDE and BCDE molecular fragments of the limonoids havanensin and azadiradione has been achieved from cyclocitral and drimenal in seven steps in overall yields of 20 and 9%, respectively.
Fernández-Mateos
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Universidad de Salamanca, Facultad de C. Químicas, Departamento de Química Orgánica, Plaza de los Caídos 1-5, 37008 Salamanca, Spain. afmateos@usal.es
Mateos Burón
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Martín de la Nava
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Rubio González
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D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D007202:Indicators and Reagents; D036701:Limonins / Q000032:analysis / Q000138:chemical synthesis*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
D007202:Indicators and Reagents; D036701:Limonins; C479321:azadiradione; C479320:havanensin