title: Blood cardioplegia filtration.
abstract: The introduction of blood cardioplegia has been proven to limit ischaemia and reperfusion injury in cardiac surgery. But the presence of activated neutrophils in the capillary bed may cause further damage. Leukocyte filters have been shown to be very effective in reducing the leukocytes in blood cardioplegia to less than 10%. Leukocyte depletion of blood cardioplegia provides an excellent approach to minimizing myocardial injury, predominantly in high-risk cardiac surgery.
authors.affiliation: Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany. Martin@ch11.ukl.uni-freiburg.de
authors.forename: Juergen
authors.initials: J
authors.lastname: Martin
authors.forename: Matthias
authors.initials: M
authors.lastname: Krause
authors.forename: Christoph
authors.initials: C
authors.lastname: Benk
authors.forename: Georg
authors.initials: G
authors.lastname: Lutter
authors.forename: Michael
authors.initials: M
authors.lastname: Siegenthaler
authors.forename: Friedhelm
authors.initials: F
authors.lastname: Beyersdorf
mesh_terms: D000818:Animals; D006348:Cardiac Surgical Procedures / Q000379:methods; D002314:Cardioplegic Solutions / Q000378:metabolism* / Q000627:therapeutic use; D005374:Filtration; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation* / Q000379:methods; D007962:Leukocytes / Q000166:cytology / Q000502:physiology; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D002314:Cardioplegic Solutions