[Renal damage during type I cryoglobulinemia].
CHARACTERISTICS OF THE RENAL DAMAGE: Type I cryoglobulinemia, composed of a single monoclonal immunoglobulin, may be responsible for a glomerulopathy with clinical presentation and histological characteristics close to those of mixed cryoglobulinemia.


BACKGROUND
Type I cryoglobulins complicate a malignant haematological disease, chronic lymphoid leukaemia or non-Hodgkin's malignant lymphoma in 60% of cases.


RESULTS
Treatment with corticosteroids and immunosuppressors or antimitotics often leads to the parallel stabilisation or remission of the renal manifestations and the haematological disease
Bridoux
Frank
F
Service de néphrologie, hémodialyse et transplantation rénale, Hôpital Jean Bernard, CHU Poitiers. f.bridoux@chu-poitiers.fr
Provôt
François
F
Ayache
Ramzi Abou
RA
Goujon
Jean-Michel
JM
Touchard
Guy
G
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D001706:Biopsy; D003449:Cryoglobulinemia / Q000145:classification / Q000150:complications* / Q000276:immunology; D005260:Female; D006526:Hepatitis C / Q000150:complications / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009393:Nephritis / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000628:therapy; D009404:Nephrotic Syndrome / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000628:therapy
D000305:Adrenal Cortex Hormones; D007136:Immunoglobulins; D007166:Immunosuppressive Agents
Atteinte rénale au cours des cryoglobulinémies de type I.