Phytoestrogens--mechanism of action and effect on bone markers and bone mineral density.
Dietary supplements, especially those containing phytoestrogens, frequently are used to either promote health or prevent disease. An estimated 20 billion dollars was spent on dietary supplements in the year 2000. Approximately 40% to 55% of Americans use supplements on a regular basis and 24% of these supplements contain herbs. Phytoestrogens are defined as any compound that is structurally or functionally related to ovarian or placental estrogens and their active metabolites. These compounds are widely used for various disorders related to women's health.
Fitzpatrick
Lorraine A
LA
Division of Endocrinology, Metabolism, Diabetes Nutrition & Internal Medicine, Department of Medicine, Endocrine Research Unit, Mayo Clinic and Mayo Foundation, Joseph 5-194, 200 First Street SW, Rochester, MN 55905, USA. fitz@mayo.edu
D015415:Biomarkers; D015519:Bone Density / Q000187:drug effects*; D001842:Bone and Bones / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D002986:Clinical Trials as Topic; D019587:Dietary Supplements; D004968:Estrogens, Non-Steroidal / Q000145:classification / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007529:Isoflavones / Q000627:therapeutic use; D010024:Osteoporosis / Q000517:prevention & control; D048789:Phytoestrogens; D028321:Plant Preparations
D015415:Biomarkers; D004968:Estrogens, Non-Steroidal; D007529:Isoflavones; D048789:Phytoestrogens; D028321:Plant Preparations