title: Lower limb SSEP changes in stroke-predictive values regarding functional recovery.
abstract: OBJECTIVE
  To assess the predictive value of lower limbs somatosensory evoked potentials (SSEPs) in the acute phase of stroke.
  
  
  METHODS
  94 stroke patients (mean age: 61.2; S.D.: 11.8; 43 women) were included. Computed tomography confirmed diagnosis was cortical middle cerebral artery (MCA) infarction in 35, subcortical MCA in 11, and mixed in 25. By size, infarctions were large (29), limited (33), and lacunar (9). Thalamic haemorrhage was found in eight patients, putaminal in seven, small capsular in two, massive in two and lobar in four patients. All patients presented with hemiparesis (54) or hemiplegia (40), pure in five and combined with hemihypesthesia in 89. Tibial nerve SSEPs were recorded early in the course of the disease (up to third day). SSEP parameters (presence/absence of SSEP, absolute P40 latency, amplitude and amplitude ratio-affected/healthy side of P40-N50) were evaluated and compared with motor ability using the Medical Research Council (MRC) scale, and daily living activities using Barthel index (ADLB) followed for 3 months after stroke. Disability was assessed after the Rankin scale.
  
  
  RESULTS
  The absolute amplitude of P40 has moderately strong correlation with Barthel index (r=0.63) and nearly moderate (r=-0.46) with Rankin scale at 3 months. P40 ratio exhibits weaker correlations with clinical outcome parameters. The combination of SSEP abnormalities and MRC has stronger predictive value than MRC alone (P<0.0001 vs P<0.03).
  
  
  CONCLUSIONS
  Tibial SSEP investigation early in stroke, independently or combined with muscle power assessment, significantly increases prognostic capability.
authors.affiliation: Stroke Unit, Department of Neurology, Medical University of Pleven, Georgi Kochev str. 8A, Pleven 5800, Bulgaria. tzvetanovplamen@hotmail.com
authors.forename: Pl
authors.initials: P
authors.lastname: Tzvetanov
authors.forename: R T
authors.initials: RT
authors.lastname: Rousseff
authors.forename: Iv
authors.initials: I
authors.lastname: Milanov
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000150:complications*; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007866:Leg / Q000502:physiology; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000473:pathology; D010291:Paresis / Q000209:etiology; D011237:Predictive Value of Tests; D011379:Prognosis; D020521:Stroke / Q000473:pathology*; D014057:Tomography, X-Ray Computed