Macular thickness measurements in healthy subjects with different axial lengths using optical coherence tomography.
OBJECTIVE
To evaluate the retinal thickness of the macula in healthy subjects with different axial lengths.


METHODS
Included were 203 healthy subjects (116 males and 87 females). The axial length of the eyes ranged from 22.68 to 30.22 mm. Four optical coherence tomograms were obtained in a radial spoke pattern centered on the central fovea. Retinal thickness was calculated from the inner and outer retinal boundaries. The average retinal thickness in three circular areas surrounding the central fovea (350, 1,850, and 2,850 microm in diameter) was determined.


RESULTS
The retinal thickness in the three circular areas was not significantly correlated with the axial length of the eye (P = 0.10, P = 0.39, and P = 0.12). There also was no statistically significant difference found between the average thickness in emmetropic and low myopic, mildly myopic, and highly myopic eyes in the three circular areas (P = 0.35, P = 0.38, and P = 0.14).


CONCLUSIONS
When eyes with pathologic myopia were excluded, the axial length of the eye was found not to influence the average retinal thickness in the macular area.
Wakitani
Yoshikatsu
Y
Department of Ophthalmology, Mie University School of Medicine, Tsu Mie, Japan.
Sasoh
Mikio
M
Sugimoto
Masahiko
M
Ito
Yoshikazu
Y
Ido
Masashi
M
Uji
Yukiyaka
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007368:Interferometry; D008027:Light; D008266:Macula Lutea / Q000033:anatomy & histology* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000145:classification / Q000473:pathology; D012016:Reference Values; D012737:Sex Factors; D014054:Tomography