title: Lateral force transmission across costameres in skeletal muscle.
abstract: In skeletal muscle, contractile force can be transmitted laterally between the z-disks and M-lines of neighboring myofibrils, across the sarcolemma, and through the extracellular matrix to the tendon. Here we examine the data that support this model and the sarcolemmal properties and structures, termed "costameres," that are consistent with it.
authors.affiliation: Department of Physiology, University of Maryland School of Medicine, Baltimore 21201, USA. rbloch@umaryland.edu
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Bloch
authors.forename: Hugo
authors.initials: H
authors.lastname: Gonzalez-Serratos
mesh_terms: D008841:Actin Cytoskeleton / Q000502:physiology / Q000648:ultrastructure; D000818:Animals; D003599:Cytoskeleton / Q000502:physiology / Q000648:ultrastructure*; D016189:Dystrophin / Q000378:metabolism; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D007150:Immunohistochemistry; D016023:Integrins / Q000502:physiology; D008953:Models, Anatomic; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology* / Q000648:ultrastructure*
chemical_list: D016189:Dystrophin; D016023:Integrins