title: Extramedullary relapse in the pleura in acute promyelocytic leukemia.
abstract: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloblastic leukemia with specific clinical, morphologic and genetic features and a good response to all trans retinoic acid (ATRA). However, extramedullary (EM) relapse is an interesting feature of these cases, especially those treated with ATRA. Recently, we have encountered an EM relapse in the pleura in a case with APL receiving an ATRA containing regimen. This case is reported and the relevant literature is reviewed.
authors.affiliation: Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey.
authors.forename: Umut
authors.initials: U
authors.lastname: Disel
authors.forename: Sinan
authors.initials: S
authors.lastname: Yavuz
authors.forename: Semra
authors.initials: S
authors.lastname: Paydas
authors.forename: Berksoy
authors.initials: B
authors.lastname: Sahin
authors.forename: Handan
authors.initials: H
authors.lastname: Zeren
mesh_terms: D000328:Adult; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy / Q000473:pathology*; D017254:Leukemic Infiltration; D008297:Male; D016066:Pleural Effusion, Malignant / Q000737:chemistry; D010997:Pleural Neoplasms / Q000209:etiology* / Q000473:pathology; D012008:Recurrence; D023981:Sarcoma, Myeloid / Q000209:etiology* / Q000473:pathology; D014212:Tretinoin
chemical_list: D014212:Tretinoin