title: [Indication and surgical outcome in hepatocellular carcinoma with infiltration of blood vessels, bile ducts and lymph nodes].
abstract: From 1995 to 2001, 243 patients with hepatocellular carcinoma were recorded at Jena University Hospital, 59 (24%) underwent curative hepatic resection or orthotopic liver transplantation. 28 tumors (12%) showed microvascular invasion, and 29 (12%) presented with gross vascular invasion. 32 patients (13%) had regional lymph node metastases. In one patient (0.4%) CT scan showed involvement of the extrahepatic bile duct. Curative removal of the tumor was possible in 61%, 21%, 3% and 0%, respectively. Vascular invasion did not influence survival statistically significant. 3 year survival rates in patients with and without regional lymph node involvement were 0% and 38% (p < 0.01).
authors.affiliation: Klinik für Allgemeine und Viszerale Chirurgie, Universitätsklinikum, Bachstrasse 18, 07740 Jena.
authors.forename: A
authors.initials: A
authors.lastname: Altendorf-Hofmann
authors.forename: J
authors.initials: J
authors.lastname: Scheele
mesh_terms: D001650:Bile Duct Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000098:blood supply* / Q000473:pathology; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D009367:Neoplasm Staging; D015996:Survival Rate; D019043:Vascular Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery
vernacular_title: Indikation und Operationsergebnisse beim hepatozellulären Karzinom mit Infiltration der Gefässe, Gallengänge und Lymphknoten.