title: Phylogenetic web profiler.
abstract: Phylogenetic Web Profiler (PWP) is a web-based service designed to perform phylogenetic profiling of proteins against genomes. The current version offers a selection of 63 completed genomes and available plasmids as annotated in the PEDANT genome database. Unlike currently available applications, this tool offers several choices of ortholog prediction parameters including E-value cutoff, percent length difference tolerance, and annotation similarity. Additional features include tight integration with the PEDANT database and tools to analyze properties of predicted proteins. PWP should prove very useful for the analysis of functional-linkage between proteins.
authors.affiliation: Department of Biochemistry, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
authors.forename: Philip
authors.initials: P
authors.lastname: Wong
authors.forename: Grigory
authors.initials: G
authors.lastname: Kolesov
authors.forename: Dmitrij
authors.initials: D
authors.lastname: Frishman
authors.forename: Walid A
authors.initials: WA
authors.lastname: Houry
mesh_terms: D000595:Amino Acid Sequence; D019143:Evolution, Molecular; D020869:Gene Expression Profiling / Q000379:methods*; D014644:Genetic Variation; D020407:Internet; D008969:Molecular Sequence Data; D010802:Phylogeny; D011506:Proteins / Q000235:genetics*; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins