title: Palliation and survival in metastatic tumors compressing the cauda equina: a 19-year radiotherapeutic experience.
abstract: PURPOSE; Radiotherapy (RT) offers a means of promoting an acceptable quality of life in people with incurable cancer. We reviewed our radiotherapeutic experience of metastatic tumors compressing the cauda equina (MTCCE) because large case series and achieved palliation in these patients are infrequently documented in the literature.
  
  
  METHODS
  Seventy-six individuals undergoing RT for MTCCE were identified from a 19-year period (1981-1999). Treatment responses and survival were assessed.
  
  
  RESULTS
  Pain relief was complete in 94%, partial in 3%, and not achieved in 3% of the 32 evaluated patients. Complete resolution of impaired sensation in the lower limbs occurred in three cases, and of anal or bladder sphincter dysfunction in three persons also. Among the 28 evaluable individuals with lower extremity motion impairment, 11 (39%) were nonambulatory and 17 (61%) were ambulatory following treatment. The overall median survival was 3 months; the survival rate at 1 year was 18% and at 3 years 8%.
  
  
  CONCLUSIONS
  Although long-term survival is not to be expected, the usefulness of RT for palliation of MTCCE may be trusted.
authors.affiliation: Department of Radiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA. fampil@lsuhsc.edu
authors.forename: Federico L
authors.initials: FL
authors.lastname: Ampil
authors.forename: Gloria
authors.initials: G
authors.lastname: Caldito
authors.forename: Maureen
authors.initials: M
authors.lastname: Heldmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002420:Cauda Equina / Q000473:pathology*; D005260:Female; D006302:Health Services Research; D006801:Humans; D008145:Louisiana; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology / Q000532:radiotherapy*; D010166:Palliative Care / Q000379:methods*; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011788:Quality of Life; D015996:Survival Rate; D013727:Terminal Care; D016896:Treatment Outcome