Synthesis and inverse electron demand Diels-Alder reactions of 3,6-bis(3,4-dimethoxybenzoyl)-1,2,4,5-tetrazine.
The synthesis of 3,6-bis(3,4-dimethoxybenzoyl)-1,2,4,5-tetrazine (2) and the scope of its reactivity in inverse electron demand Diels-Alder reactions are disclosed representing the first systematic study of the [4 + 2] cycloaddition reactions of 3,6-diacyl-1,2,4,5-tetrazines.
Soenen
Danielle R
DR
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Zimpleman
Jeffrey M
JM
Boger
Dale L
DL
D020650:Combinatorial Chemistry Techniques; D006573:Heterocyclic Compounds, 1-Ring; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis*; D062425:Hydroxybenzoate Ethers; D062385:Hydroxybenzoates / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
C479322:3,6-bis(3,4-dimethoxybenzoyl)-1,2,4,5-tetrazine; D006573:Heterocyclic Compounds, 1-Ring; D006575:Heterocyclic Compounds, 3-Ring; D062425:Hydroxybenzoate Ethers; D062385:Hydroxybenzoates; D007202:Indicators and Reagents