title: Osseointegration under immediate loading: biomechanical stress-strain and bone formation--resorption.
abstract: During the past 10 years, clinicians have used two-piece implants as a one-piece system for immediate loading to accomplish early recovery for function and esthetics. The statistical analysis by the Institute of Clinical Materials demonstrates high survival rates of 92.3 +/- 8.3%. Animal experiments of beagle dogs have been carried out to analyze successful conditions of immediate loading according to the dependency of bone formation--resorption upon the biomechanical stress--strain of bone. Histometric investigations clarified that the micromotion of less than 30 microns at the implant-bone interface did not interfere with the osteogenesis and new bone growth at the implant-bone interface. Bone formation and resorption are discussed from the standpoint of minimum effective strain on living bone.
authors.affiliation: Osaka Dental University, President, Institute of Clinical Materials, Osaka, Japan. icm@sea.plala.or.jp
authors.forename: Haruyuki
authors.initials: H
authors.lastname: Kawahara
authors.forename: Dai
authors.initials: D
authors.lastname: Kawahara
authors.forename: Masahide
authors.initials: M
authors.lastname: Hayakawa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Tamai
authors.forename: Tokio
authors.initials: T
authors.lastname: Kuremoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Matsuda
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001732:Bite Force; D001862:Bone Resorption / Q000503:physiopathology*; D000044:Dental Abutments; D003759:Dental Implantation, Endosseous, Endodontic; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D003830:Denture, Partial, Fixed; D004285:Dogs; D008334:Mandible / Q000473:pathology / Q000502:physiology / Q000601:surgery; D016348:Osseointegration; D010012:Osteogenesis / Q000502:physiology*; D013314:Stress, Mechanical; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium; D016474:Weight-Bearing / Q000502:physiology
chemical_list: D015921:Dental Implants; D014025:Titanium