New dihydroalkylhexenones from Lannea edulis.
Activity-guided isolation of radical-scavenging compounds from the dichloromethane extract of the root bark of Lannea edulis led to isolation of two known bioactive alkylphenols [cardonol 7 (1) and cardonol 13 (2)], and three new dihydroalkylhexenones were also isolated (3-5). Their structures were elucidated by spectroscopic and chemical methods. The absolute configuration of 4 was determined by the Mosher ester method.
Queiroz
Emerson F
EF
Institute of Pharmacognosy and Phytochemistry, University of Lausanne, BEP, CH-1015 Lausanne, Switzerland.
Kuhl
Celestina
C
Terreaux
Christian
C
Mavi
Stephen
S
Hostettmann
Kurt
K
D027926:Anacardiaceae / Q000737:chemistry*; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006588:Hexanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010851:Picrates; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D015030:Zimbabwe
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006588:Hexanones; D010636:Phenols; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl