Guidelines for the laboratory investigation of inherited thrombophilias. Recommendations for the first level clinical laboratories.
Recent advances in the laboratory diagnostic approach to inherited thrombophilia call for an update on laboratory strategies and organization. The present paper therefore deals in particular with: the panel test choice, timing and test appropriateness, and analytical methods in several clinical conditions. Specific recommendations are supported by the state-of-the-art in this branch.
Carraro
Paolo
P
Department of Laboratory Medicine, Padova University-Hospital, Padova, Italy. pcarraro@hotmail.com
D020152:Antithrombin III Deficiency / Q000235:genetics; D003955:Diagnostic Tests, Routine / Q000592:standards; D005165:Factor V / Q000032:analysis; D005260:Female; D006801:Humans; D007753:Laboratories / Q000592:standards*; D011247:Pregnancy; D020151:Protein C Deficiency / Q000235:genetics; D018455:Protein S Deficiency / Q000235:genetics; D011786:Quality Control; D012015:Reference Standards; D015203:Reproducibility of Results; D019851:Thrombophilia / Q000175:diagnosis* / Q000235:genetics* / Q000503:physiopathology
D005165:Factor V