[Cost-effectiveness analysis: a reader's guide].
BACKGROUND
This article is devoted to the critical appraisal of cost-effectiveness analysis.


METHODS
The example chosen concerns the choice of first line chemotherapy for a patient with stage IV non small cell bronchial carcinoma; a common problem in thoracic oncology. It compares three chemotherapy regimes: vinorelbine alone, cisplatin-vinorelbine and cisplatin-vindesine.


CONCLUSIONS
The guide used allows evaluation of the validity of the methodology and, therefore, of the results obtained.


CONCLUSIONS
The article studies the possible application of these results to the patient whose clinical history was presented as an introduction. The limitations of cost-effectiveness analyses are also considered.
Vergnenègre
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Service de l'Information Médicale et de l'Evaluation, Hôpital du Cluzeau, CHU Dupuytren, Limoges cedex, France. avergne@unilim.fr
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000191:economics* / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000191:economics* / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000191:economics* / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D002945:Cisplatin / Q000008:administration & dosage / Q000191:economics* / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003362:Cost-Benefit Analysis; D003627:Data Interpretation, Statistical; D019317:Evidence-Based Medicine; D006801:Humans; D016015:Logistic Models; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D008297:Male; D008875:Middle Aged; D014747:Vinblastine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000191:economics* / Q000627:therapeutic use*; D014751:Vindesine / Q000008:administration & dosage / Q000191:economics* / Q000627:therapeutic use*; D000077235:Vinorelbine
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D002945:Cisplatin; D000077235:Vinorelbine; D014751:Vindesine
L'analyse coût-efficacité: un guide de lecture.