title: Implantable microelectrodes with new electro-conductive materials for recording sympathetic neural discharge.
abstract: We have developed two new types of bipolar cuff microelectrodes (volume size, 2-3 mm(3)) using electro-conductive rubber or water-absorbent polymer, either of which can be applied to measure sympathetic nerve activity in small animals. A renal nerve bundle of an anesthetized rat was inserted into the center hole of the electrode (diameter, 0.15 mm) through a slit and had good contact with the electrodes. Renal sympathetic nerve activity, which was verified by sympathetic ganglionic blockade, could be recorded using either type of implantable cuff electrode.
authors.affiliation: Department of Physiology, Institute of Health Sciences, Hiroshima University Faculty of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551 Japan. matsuk@hiroshima-u.ac.jp
authors.forename: Kanji
authors.initials: K
authors.lastname: Matsukawa
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Komine
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Tsuchimochi
authors.forename: Jun
authors.initials: J
authors.lastname: Murata
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Yonezawa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kondo
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Seki
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D004567:Electrodes, Implanted; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D007668:Kidney / Q000294:innervation* / Q000502:physiology*; D008839:Microelectrodes; D010525:Peripheral Nerves / Q000502:physiology*; D051381:Rats; D013564:Sympathetic Nervous System / Q000502:physiology*