MR-guided catheter navigation of the intracranial subarachnoid space.
Percutaneous intraspinal navigation (PIN) is a new minimally invasive approach to the CNS. The authors studied the utility of MR-guided intracranial navigation following access to the subarachnoid compartment via PIN. The passive tracking technique was employed to visualize devices during intracranial navigation. Under steady-state free precession (SSFP) MR-guidance a microcatheter-microguidewire was successfully navigated to multiple brain foci in two cadavers. SSFP MR fluoroscopy possesses adequate contrast and temporal resolution to allow MR-guided intracranial navigation.
Rappard
George
G
Department of Radiology, Division of Neuroradiology, the University of Texas Southwestern Medical Center at Dallas, USA.
Metzger
Gregory J
GJ
Fleckenstein
James L
JL
Babcock
Evelyn E
EE
Weatherall
Paul T
PT
Replogle
Robert E
RE
Pride
G Lee
GL
Miller
Susan L
SL
Adams
Christina E
CE
Purdy
Phillip D
PD
D001921:Brain / Q000473:pathology*; D002408:Catheters, Indwelling; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004867:Equipment Design; D005240:Feasibility Studies; D005471:Fluoroscopy; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D038361:Neuronavigation / Q000295:instrumentation*; D012680:Sensitivity and Specificity; D013129:Spinal Puncture / Q000295:instrumentation*; D013346:Subarachnoid Space / Q000473:pathology*