title: [First experiences with fluorodeoxyglucose-positron-emission tomography (FDG-PET) in the evaluation of painful total knee and hip joint replacements].
abstract: OBJECTIVE
  The aim of the study was to describe first experiences using FDG-PET in the examination of painful arthroplasties.
  
  
  METHODS
  12 patients prior to revision of a total hip or knee joint replacement underwent PET. Histopathology, microbiological analysis and intraoperative diagnosis were compared to preoperative PET findings.
  
  
  RESULTS
  The analysis of intraoperative findings, of microbiological examinations and of histopathology showed that besides the well known determinants infection and early postoperative granulation tissue, polyethylene wear induced foreign-body reaction was a major cause for increased FDG consumption.
  
  
  CONCLUSIONS
  In vivo imaging of marked foreign-body tissue reaction induced by polyethylene wear is feasible by FDG-PET. This observation, however, leads to reduced specificity of PET imaging for the diagnosis of periprosthetic infection.
authors.affiliation: Orthopädische Universitätsklinik Aachen. kaikisielinski@yahoo.de
authors.forename: K
authors.initials: K
authors.lastname: Kisielinski
authors.forename: U
authors.initials: U
authors.lastname: Cremerius
authors.forename: U
authors.initials: U
authors.lastname: Büll
authors.forename: B
authors.initials: B
authors.lastname: Hermanns
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
authors.forename: F U
authors.initials: FU
authors.lastname: Niethard
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging* / Q000473:pathology; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000473:pathology; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging
chemical_list: D001786:Blood Glucose; D019788:Fluorodeoxyglucose F18
vernacular_title: Erste Erfahrungen mit der Fluorodeoxyglukose-Positronenemissionstomographie (FDG-PET) in der Diagnostik schmerzhafter Knie- und Hüfttotalendoprothesen.