Extrapyramidal reactions to ondansetron: cross-reactivity between ondansetron and prochlorperazine?
Ondansetron can rarely induce extrapyramidal reactions in susceptible individuals. Our patient had a history of drug-induced dystonic reaction; therefore, these patients may be susceptible to extrapyramidal adverse reactions after ondansetron.
Sprung
Juraj
J
Department of Anesthesiology, Mayo Clinic, Rochester, MN.
Choudhry
Faisal M
FM
Hall
Brian A
BA
D000328:Adult; D000932:Antiemetics / Q000009:adverse effects*; D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000503:physiopathology; D001943:Breast Neoplasms / Q000150:complications / Q000601:surgery; D003429:Cross Reactions; D005260:Female; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D009666:Nose / Q000601:surgery; D017294:Ondansetron / Q000009:adverse effects*; D011346:Prochlorperazine / Q000009:adverse effects*; D019651:Plastic Surgery Procedures
D000932:Antiemetics; D017294:Ondansetron; D011346:Prochlorperazine