title: [Hepatobiliogastroscintigraphy in assessment of the hepatobiliary system in primary cancer of the liver].
abstract: Primary cancer of the liver is characterized not only by laboratory evidence for cytolytic (87.5% cases), cholestatic (100% cases) syndromes, high levels of oncomarkers (CA-19-9, 50%; CEA, 68.75%; alpha FP, 43.75%) and activation of hemostasis system but, as shown at hepatobiligastroscintigraphy with 99m-Tc-brommeside, by at least 2-fold decline in absorptive and excretory function of hepatic polygonal cells (in 75% cases), at least a 5-fold decline in secretory function of the gallbladder (in 100% cases), cholestasis (in 100% cases) manifesting as a 3.8-fold reduction, on the average, of the ratio of secretory function of the gallbladder to that of the intrahepatic bile ducts, dilation of the latter (in 50% cases), Oddi's sphincter hypotonicity (in 50% cases). None of the patients showed duodenogastric reflux.
authors.forename: V V
authors.initials: VV
authors.lastname: Krashutskiĭ
authors.forename: S M
authors.initials: SM
authors.lastname: Pikurin
mesh_terms: D000328:Adult; D000368:Aged; D001659:Biliary Tract / Q000000981:diagnostic imaging*; D014408:Biomarkers, Tumor / Q000097:blood; D005260:Female; D005704:Gallbladder / Q000503:physiopathology; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging / Q000379:methods; D019275:Radiopharmaceuticals; D013270:Stomach / Q000000981:diagnostic imaging; D019780:Technetium Tc 99m Lidofenin
chemical_list: D014408:Biomarkers, Tumor; D019275:Radiopharmaceuticals; D019780:Technetium Tc 99m Lidofenin
vernacular_title: Gepatobiligastrostsintigrafiia v otsenke sostoianiia gepatobiliarnoĭ sistemy pri pervichnom rake pecheni.