[Effect of aluminium on meiotic maturation of mouse oocyte in vitro].
The effect of aluminium nitrate on the meiotic maturation of mouse oocyte was studied in the culture of mouse oocyte. The results showed that aluminium nitrate could inhibit the extruding of the first polar body and the dose of 30 mg/L and 60 mg/L could affect the viability of mouse oocyte, but little impact on the germinal vesicle breakdown (GVBD) of oocyte. The results indicated that aluminium nitrate might be hazardous to the meiotic maturation of mouse oocyte.
Shen
W
W
Medical College of Yangzhou University, Yangzhou 225001, China.
Ji
Q
Q
Li
C
C
Chen
Y
Y
D017607:Aluminum Compounds / Q000633:toxicity*; D000818:Animals; D000831:Animals, Newborn; D002478:Cells, Cultured; D005260:Female; D008540:Meiosis / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D009566:Nitrates / Q000633:toxicity*; D009865:Oocytes / Q000166:cytology*
D017607:Aluminum Compounds; D009566:Nitrates; C050609:aluminum nitrate