Functional perfusion imaging using continuous arterial spin labeling with separate labeling and imaging coils at 3 T.
Functional perfusion imaging with a separate labeling coil located above the common carotid artery was demonstrated in human volunteers at 3 T. A helmet resonator and a spin-echo echo-planar imaging (EPI) sequence were used for imaging, and a circular surface coil of 6 cm i.d. was employed for labeling. The subjects performed a finger-tapping task. Signal differences between the condition of finger tapping and the resting state were between -0.5% and -1.1 % among the subjects. The imaging protocol included a long post-label delay (PLD) to reduce transit time effects. Labeling was applied for all repetitions of the functional run to reduce the sampling interval.
Mildner
Toralf
T
Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany. mildner@cns.mpg.de
Trampel
Robert
R
Möller
Harald E
HE
Schäfer
Andreas
A
Wiggins
Christopher J
CJ
Norris
David G
DG
D000328:Adult; D017536:Carotid Artery, Common / Q000502:physiology; D017352:Echo-Planar Imaging; D005385:Fingers / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D010477:Perfusion / Q000295:instrumentation; D013113:Spin Labels
D013113:Spin Labels