title: [Evaluation of abnormal myocardial wall motions in patients with univentricular heart by tissue Doppler echocardiography].
abstract: BACKGROUND
  Assessment of systolic and diastolic ventricular function in children and adults with morphologically and functionally univentricular heart is difficult using the conventional echocardiographic methods. Quantitative assessment of systolic and diastolic wall motion by TDE may provide information on abnormal systolic and diastolic ventricular function. Thus, the object of this study was to analyze the patterns of anterior and posterior wall motions in children with univentricular heart after palliative Fontan operation in comparison to normal subjects.
  
  
  METHODS
  We investigated 21 patients of an average age of 10.1 years (range 4.2 to 32 years) with the primary diagnosis of univentricular heart and tricuspid atresia after a median period of 4.3 (range 1.2 to 8) years after cavo-pulmonary anastomosis (Fontan procedure) and in comparison to a normal collective of children without cardiovascular malformations. For investigation we used the novel tissue Doppler echocardiography (TDE) (EchoPack 6.3.6, Vingmed, Norway). Thereby we chose the standardized apical view and evaluated the left and right annular systolic (S(T)), early diastolic (E(T)) and atrial (A(T)) motion. We also registered the acceleration and deceleration time of each obtained curve.
  
  
  RESULTS
  In comparison to the posterior myocardial wall the velocities at the anterior wall of the rudimentary ventricle were significantly reduced in all patients with tricuspid atresia and univentricular heart (p<0.0001). Particularly the annular systolic and diastolic wall motions of the rudimentary ventricle as well as their deceleration and acceleration time in patients with univentricular hearts differed significantly from those in healthy persons.
  
  
  CONCLUSIONS
  Abnormal myocardial wall motion is detectable in children and adults with univentricular heart after palliative cardiac procedures using tissue Doppler echocardiography. The hemodynamic value of the measured abnormal wall motions, however, need further comparative studies.
authors.affiliation: Klinik für Angeborene Herzfehler und Kinderkardiologie, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. Abdul-Khaliq@dhzb.de
authors.forename: H
authors.initials: H
authors.lastname: Abdul-Khaliq
authors.forename: B
authors.initials: B
authors.lastname: Schmitt
authors.forename: A
authors.initials: A
authors.lastname: Rentzsch
authors.forename: A
authors.initials: A
authors.lastname: Helweg
authors.forename: M
authors.initials: M
authors.lastname: Gutberlet
authors.forename: M
authors.initials: M
authors.lastname: Yegitbasi
authors.forename: J H
authors.initials: JH
authors.lastname: Nürnberg
authors.forename: V
authors.initials: V
authors.lastname: Alexi-Meskhishvili
authors.forename: R
authors.initials: R
authors.lastname: Hetzer
authors.forename: P E
authors.initials: PE
authors.lastname: Lange
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013599:Systole / Q000502:physiology; D018785:Tricuspid Atresia / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery
vernacular_title: Evaluation abnormer Myokardwandgeschwindigkeiten des univentrikulären Herzens mittels Gewebedoppler-Echokardiographie.