Myopic strabismus fixus: a mitochondrial myopathy?
OBJECTIVE
Ultrastructural analysis of extraocular muscle in a case of myopic strabismus fixus.


METHODS
Interventional case report.


METHODS
Incisional biopsy and ultrastuctural analysis of recti muscles in a female patient with myopic strabismus fixus.


RESULTS
Ultrastuctural analysis revealed evidence of mitochondrial myopathy.


CONCLUSIONS
Acquired strabismus fixus due to high myopia may be a manifestation of mitochondrial myopathy, a finding that has not been previously reported.
Venkatesh
Canjeevaram P
CP
Vittala International Institute of Ophthalmology, Bangalore, India. cpvenky@yahoo.com
Gayathri
Narayanappa
N
Murthy
Krishnamoorthy R
KR
D000328:Adult; D004948:Esotropia / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D008931:Mitochondria, Muscle / Q000648:ultrastructure; D017240:Mitochondrial Myopathies / Q000209:etiology* / Q000473:pathology; D009210:Myofibrils / Q000648:ultrastructure; D009216:Myopia / Q000150:complications*; D009801:Oculomotor Muscles / Q000601:surgery / Q000648:ultrastructure*