title: Systemic 5-fluorouracil producing an inflammatory response in porokeratosis.
abstract: Topical 5-fluorouracil has been used as an effective treatment for porokeratosis. Upon its treatment, an inflammatory effect occurs with the topical 5-fluorouracil. We report a case of a patient with disseminated superficial actinic porokeratosis displaying a comparable inflammatory process following therapy with systemic 5-fluorouracil used to manage a metastatic breast cancer.
authors.affiliation: Boston University School of Medicine, Roger Williams Medical Center, Department of Dermatology and Skin Surgery, Providence, Rhode Island 02908, USA.
authors.forename: W K
authors.initials: WK
authors.lastname: Nahm
authors.forename: K G
authors.initials: KG
authors.lastname: Donohue
authors.forename: J F
authors.initials: JF
authors.lastname: Danahy
authors.forename: E
authors.initials: E
authors.lastname: Badiavas
authors.forename: V
authors.initials: V
authors.lastname: Falanga
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D017499:Porokeratosis / Q000188:drug therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil