Definitions of enzyme function for the structural genomics era.
Questions are being asked about how enzyme function is described at the molecular level and the strengths and weaknesses of the EC system for this purpose. A new approach to describing enzyme function has been proposed that might improve our capabilities for functional inference for members of enzyme superfamilies.
Babbitt
Patricia C
PC
Department of Biopharmaceutical Sciences, University of California, 513 Parnassus Street, San Francisco, CA 94143-0446, USA. babbitt@cgl.ucsf.edu
D000818:Animals; D004798:Enzymes / Q000737:chemistry / Q000145:classification* / Q000235:genetics; D023281:Genomics / Q000639:trends*; D006801:Humans; D013329:Structure-Activity Relationship; D009626:Terminology as Topic
D004798:Enzymes