[Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus].
The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase 50-100-fold.
Gavrilov
B G
BG
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia. bgg@humgen.siobc.ras.ru
Monastyrskaia
G S
GS
Velikodvorskaia
T V
TV
Filiukova
O B
OB
Konovalova
S N
SN
Kachko
A A
AA
Protopopova
E V
EV
Nikolaev
L G
LG
Loktev
V B
VB
Sverdlov
E D
ED
D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; D002478:Cells, Cultured; D004669:Encephalitis Viruses, Tick-Borne / Q000378:metabolism* / Q000472:pathogenicity; D005786:Gene Expression Regulation; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods; D007668:Kidney / Q000166:cytology / Q000196:embryology / Q000502:physiology / Q000821:virology*; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000032:analysis; D016601:RNA-Binding Proteins; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014776:Virus Cultivation
D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; C484290:IFIT1 protein, human; C484289:IFIT2 protein, human; D011506:Proteins; D012333:RNA, Messenger; D016601:RNA-Binding Proteins
Pozdniaia aktivatsiia interferonindutsiruemykh genov IFI-54k i IFI-56k pri infektsii kletok linii RH cheloveka virusom kleshchevogo éntsefalita.