title: An appraisal of post-irradiation metabolic changes in toad liver (Bufo melanostictus).
abstract: Whole body 60Co gamma irradiation of B . melanostictus with two sublethal doses of 3.5 and 7 Gy resulted in a significant increase (P < 0.001) in total lipid (hyperlipidemia), cholesterol content (hypercholesterolemia) and total free amino acid content, and significant decrease (P < 0.001) in total protein content in the liver tissues on post-irradiation day (PID) 1, 5 and 10 as compared to controls. The ratio of total lipid to cholesterol showed a gradual declining trend by PID-10 in the treated groups as compared to controls. However, it was more pronounced in the 7 Gy treated group. An observation on the ratio of total protein to total free amino acid content also showed a similar declining trend by PID-10 in both the treated groups as compared to controls.
authors.affiliation: School of Life Sciences, Jyoti Vihar, Sambalpur University, Burla 768 019, India.
authors.forename: J
authors.initials: J
authors.lastname: Mishra
authors.forename: A
authors.initials: A
authors.lastname: Mittra
mesh_terms: D000818:Animals; D002025:Bufonidae; D004307:Dose-Response Relationship, Radiation; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*