title: Neurologic complications of cancer therapy.
abstract: Neurologic complications of chemotherapy are relatively common. The diagnosis of chemotherapy-associated neurotoxicity remains a clinical one, and is largely based on the exclusion of other possible causes. The goal of this review is to describe the neurotoxicity associated with established chemothrerapeutic agents and with some of the newer biologic agents, monoclonal antibodies and targeted molecular therapies used in the treatment of cancer.
authors.affiliation: Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02446, USA.
authors.forename: Scott R
authors.initials: SR
authors.lastname: Plotkin
authors.forename: Patrick Y
authors.initials: PY
authors.lastname: Wen
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D010523:Peripheral Nervous System Diseases / Q000209:etiology*
chemical_list: D000276:Adjuvants, Immunologic; D018931:Antineoplastic Agents, Hormonal