Cancer Chemoprevention by Phytochemicals and their Related Compounds.
Cancer chemoprevention by phytochemicals may be one of the most feasible approaches for cancer control. For example, phytochemicals obtained from vegetables, fruits, spices, teas, herbs and medicinal plants, such as carotenoids, phenolic compounds and terpenoids, have been proven to suppress experimental carcinogenesis in various organs. These candidates should be evaluated by intervention studies, before acceptance as cancer preventive agents for human application. Phytochemicals may also be useful to develop "designer foods" or "functional foods" for cancer prevention. We are now planning animal foods, such as meats, eggs and milk, which contain anti-carcinogenic phytochemicals. In prototype experiments, expression of genes for synthesis of phytochemicals, such as phytoene and limonene, has been successful in cultured animal cells.
Nishino
Hoyoku
H
Department of Biochemistry, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. hnishino@basic.kpu-m.ac.jp
Tokuda
Harukuni
H
Satomi
Yoshiko
Y
Masuda
Mitsuharu
M
Onozuka
Mari
M
Yamaguchi
Shino
S
Takayasu
Junko
J
Tsuruta
Jun
J
Takemura
Manabu
M
Ii
Tsunehiro
T
Ichiishi
Eiichiro
E
Kuchide
Shouji
S
Okuda
Masato
M
Murakoshi
Michiaki
M