Composite hopanoid biosynthesis in Zymomonas mobilis: N-acetyl-D-glucosamine as precursor for the cyclopentane ring linked to bacteriohopanetetrol.
A selective labelling of the two major composite hopanoids of Z. mobilis with deuterated N-acetyl-D-glucosamine showed that this carbohydrate is a common precursor of the glucosamine or the cyclopentitol moieties respectively linked to bacteriohopanetetrol by a glycosidic or an ether bond.
Vincent
Stéphane P
SP
Ecole Normale Supérieure, Département de Chimie, UMR-8642 du CNRS, 24 rue Lhomond, 75231 Paris Cedex 05, France.
Sinaÿ
Pierre
P
Rohmer
Michel
M
D000117:Acetylglucosamine / Q000737:chemistry / Q000378:metabolism*; D003517:Cyclopentanes / Q000737:chemistry / Q000378:metabolism*; D003903:Deuterium; D004986:Ether / Q000737:chemistry; D006017:Glycolipids / Q000737:chemistry / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry / Q000378:metabolism; D012255:Ribitol / Q000737:chemistry / Q000378:metabolism; D014315:Triterpenes / Q000737:chemistry* / Q000378:metabolism*; D017355:Zymomonas / Q000378:metabolism*
D003517:Cyclopentanes; D006017:Glycolipids; D006027:Glycosides; D014315:Triterpenes; D004986:Ether; C025206:hopane; D012255:Ribitol; D003903:Deuterium; D000117:Acetylglucosamine