Frontal fibrosing alopecia.
Two cases of frontal fibrosing alopecia in post menopausal women, one of them biopsy-proven, are reported. Both women showed a progressive marginal alopecia and none had multifocal areas of involvement typical of lichen planopilaris nor the mucosal or cutaneous lesions of lichen planus. However, scalp biopsy specimens from the frontal hair margin showed perifollicular fibrosis and lymphocytic inflammation. Because the histologic findings are indistinguishable from those seen in lichen planopilaris, frontal fibrosing alopecia is considered a variant of lichen planus pilaris with a particular specific localization and usually onset in the postmenopausal age.
Fiorucci
Maria Cristina
MC
DiSEM, Section of Dermatology, University of Genoa Viale Benedetto XV, 7, Italy.
Cozzani
Emmanuel
E
Parodi
Aurora
A
Rebora
Alfredo
A
D000368:Aged; D000505:Alopecia / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000473:pathology / Q000503:physiopathology*; D008875:Middle Aged; D017698:Postmenopause; D012536:Scalp Dermatoses / Q000473:pathology / Q000503:physiopathology*