title: On the design of active contours for medical image segmentation. A Scheme for Classification and construction.
abstract: OBJECTIVE
  To provide a comprehensive bottom-up categorization of model-based segmentation techniques that allows to select, implement, and apply well-suited active contour models for segmentation of medical images, where major challenges are the high variability in shape and appearance of objects, noise, artifacts, partial occlusions of objects, and the required reliability and correctness of results.
  
  
  METHODS
  We consider the general purpose of segmentation, the dimension of images, the object representation within the model, image and contour influences, as well as the solution and the parameter selection of the model. Potentials and limits are characterized for all instances in each category providing essential information for the application of active contours to various purposes in medical image processing. Based on prolops surgery planning, we exemplify the use of the scheme to successfully design robust 3D-segmentation.
  
  
  RESULTS
  The construction scheme allows to design robust segmentation methods, which, in particular, should avoid any gaps of dimension. Such gaps result from different image domains and value ranges with respect to the applied model domain and the dimension of relevant subsets for image influences, respectively.
  
  
  CONCLUSIONS
  A general segmentation procedure with sufficient robustness for medical applications is still missing. It is shown that in almost every category, novel techniques are available to improve the initial snake model, which was introduced in 1987.
authors.affiliation: Institute of Medical Informatics, Aachen University of Technology, Aachen, Germany. lehmann@computer.org
authors.forename: T M
authors.initials: TM
authors.lastname: Lehmann
authors.forename: J
authors.initials: J
authors.lastname: Bredno
authors.forename: K
authors.initials: K
authors.lastname: Spitzer
mesh_terms: D003952:Diagnostic Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*