[The 1(2)-dehydrogenation of steroid substrates by Nocardioides simplex VKM Ac-2033D].
The bacterium formerly known as Arthrobacter globiformis 193 has high 1(2)-dehydrogenase activity toward pharmaceutically important steroids, 9(11)-dehydrocortexolone in particular. The complex analysis of the morphostructural, physiological, biochemical, and phylogenetic properties of this bacterium allowed us to reclassify it into Nocardioides simplex (N. simplex VKM Ac-2033D).
Fokina
V V
VV
Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia.
Sukhodol'skaia
G V
GV
Gulevskaia
S A
SA
Gavrish
E Iu
EIu
Evtushenko
L I
LI
Donova
M V
MV
D001173:Arthrobacter / Q000145:classification / Q000378:metabolism*; D003350:Cortodoxone / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D009618:Nocardiaceae / Q000145:classification / Q000378:metabolism*; D010802:Phylogeny; D012329:RNA, Bacterial / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D013256:Steroids / Q000737:chemistry / Q000378:metabolism*
D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D013256:Steroids; D006913:Hydroxysteroid Dehydrogenases; D003350:Cortodoxone
1(2)-degidrirovanie steroidnykh substratov shtammom Nocardioides simplex BKM Ac-2033D.