Eosinophils and eosinophil products in asthma.
Eosinophils are known to be an indirect marker of airway inflammation in asthma. It is known since long that the total eosinophil count reflects asthmatic activity and is useful for regulating steroid dosage and for early detection of exacerbations. Eosinophils are currently regarded as the effector cells responsible for much of the pathology of asthma. Eosinophil-mediated damage to the respiratory epithelium is a major pathogenetic mechanism in asthma. This article is a review of the latest works about the relationship of eosinophil and eosinophil products with asthma.
Saeed
Waseem
W
Department of Pulmonology, Military Hospital, Pakistan.
Badar
Ahmed
A
Hussain
M Mazhar
MM
Aslam
Muhammad
M
D017209:Apoptosis; D001249:Asthma / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D001798:Blood Proteins / Q000502:physiology; D047091:Eosinophil Granule Proteins; D004804:Eosinophils / Q000502:physiology*; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D007958:Leukocyte Count; D012260:Ribonucleases
D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D012260:Ribonucleases