title: Safety and feasibility of a CT protocol for acute stroke: combined CT, CT angiography, and CT perfusion imaging in 53 consecutive patients.
abstract: By combining non-contrast-enhanced CT imaging, CT perfusion imaging, and cranial-to-chest CT angiography (CTA), the entire cerebrovascular axis can be imaged during acute stroke. To our knowledge, the safety and feasibility of this technique have not been previously reported. In a consecutive series of 53 patients with suspected acute stroke, renal failure was not observed. Median imaging time was 27 minutes (range, 9-67 minutes). Image quality was degraded by motion in 1.3% of vessels studied. Dynamic CT perfusion data were successfully obtained in 52 patients (98% of patients). High-speed, multisection, helical CT scanners allow rapid, safe imaging of the entire neurovascular axis in patients with acute stroke by use of combined CT imaging, CT perfusion imaging, and CTA.
authors.affiliation: Department of Neurology, University of California, San Francisco, 94143, USA.
authors.forename: Wade S
authors.initials: WS
authors.lastname: Smith
authors.forename: Heidi C
authors.initials: HC
authors.lastname: Roberts
authors.forename: Nathaniel A
authors.initials: NA
authors.lastname: Chuang
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Ong
authors.forename: Theodore J
authors.initials: TJ
authors.lastname: Lee
authors.forename: S Claiborne
authors.initials: SC
authors.lastname: Johnston
authors.forename: William P
authors.initials: WP
authors.lastname: Dillon
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000209:etiology; D002985:Clinical Protocols; D003404:Creatinine / Q000097:blood; D003937:Diagnosis, Differential; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging* / Q000209:etiology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011856:Radiographic Image Enhancement; D012039:Regional Blood Flow / Q000502:physiology; D012307:Risk Factors; D036542:Tomography, Spiral Computed; D014057:Tomography, X-Ray Computed
chemical_list: D003404:Creatinine