SSEP analysis in surgery of idiopathic scoliosis: the influence of spine deformity and surgical approach.
The study was conducted to assess the possible impact of spine deformity in patients with idiopathic scoliosis (IS) on tibial nerve somatosensory evoked potentials (t-SSEPs) and the influence of spine correction upon postoperative SSEP recordings. In 61 consecutive patients undergoing 64 spinal instrumentations, 129 pre- and postoperative SSEPs were analyzed. The degree of spine deformity was assessed by the pre-operative Cobb angle of the major scoliotic curve. In a control group, reference values of t-SSEP latencies were established with respect to body height. In a cohort study, IS patients were compared with healthy controls with respect to t-SSEP latency, amplitude, configuration and interside difference. The results of the analysis showed that preoperative-body-height-corrected t-SSEP latencies were prolonged in 61% of patients, with a pathological interside difference in 23.4% of them. The impairment of t-SSEPs was not related to the extent of spine deformity as assessed by the Cobb angle. Even without occurrence of postoperative neurological deficits, postoperative t-SSEPs showed significantly increased latencies without changes in t-SSEP configuration. The prolongation of t-SSEP latencies was related to the surgical procedure (combined ventro-dorsal approach), but not to the extent of spine correction, level of instrumentation, or number of fused segments. The analysis of preoperative t-SSEPs was of no predictive value for intra- or postoperative neurological complications. t-SSEPs are significantly affected in IS patients, although these patients show no obvious clinical neurological deficits. The extent of t-SSEP impairment is not related to the severity of scoliosis. Even in clinically uneventful surgery, the postoperative t-SSEPs can be deteriorated depending on the surgical approach. This indicates a subclinical impact of spine surgery upon spinal cord function.
Hausmann
Oliver
O
ParaCare, Swiss Paraplegic Center, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland.
Min
Kan
K
Böni
Thomas
T
Erni
Thomas
T
Dietz
Volker
V
Curt
Armin
A
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D001827:Body Height / Q000502:physiology; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D012600:Scoliosis / Q000503:physiopathology* / Q000601:surgery*; D013116:Spinal Cord / Q000502:physiology; D013131:Spine / Q000002:abnormalities* / Q000601:surgery
D015415:Biomarkers