Time trends and occupational risk factors for peritoneal mesothelioma in Sweden.
Epidemiologic data on peritoneal mesothelioma are scarce but exposure to asbestos is an identified risk factor. To characterize the disease, time trends, age-incidence relationships, and occupational risk factors for peritoneal mesothelioma were studied based on the Swedish Family-Database covering years 1961 to 1998. Peritoneal mesothelioma is a rare disease and only 96 male and 113 female cases were recorded during the 38-year period. Age-standardized incidence of the disease has increased for men until 1985 and leveled off thereafter. The incidence in women has been equally high but it has continued to increase toward the end of the follow-up period. The incidence was maximal at an age around 80 years for both genders. No female occupational or socioeconomic group was at risk. For men, 29% of the cases had typical asbestos related jobs with a SIR of 1.70. Bricklayers and plumbers had the highest risk of 7.22 and 5.12, respectively. Within limits of the sample size, no evidence was noted for risk from environmental exposures to asbestos because the risk of farmers and that of urban residents were not different.
Hemminki
Kari
K
Department of Biosciences at Novum, Karolinska Institute, 141 57 Huddinge, Sweden. kari.hemminki@cnt.ki.se
Li
Xinjun
X
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008654:Mesothelioma / Q000453:epidemiology*; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology*; D010534:Peritoneal Neoplasms / Q000453:epidemiology*; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology