A rare case of a pulmonary granular cell tumor presenting as a coin lesion.
A 38-year-old man was found to show a well-defined oval-shaped homogeneous dense mass (20 x 30 mm) in the left upper lung field on chest X-ray. Left upper divisionectomy was performed under video-assisted thoracic surgery. Histology showed that the tumor cells had abundant eosinophilic granular cytoplasm, and were immunopositive for neuron-specific enolase, CD56, S-100 protein, and chromogranin. The proportion of Ki-67 positive cells was < 1%. An electron-microscopic examination showed many membrane-bound whorls in the cytoplasm. Although this was a very rare case presenting as an asymptomatic coin lesion, the histological features were the same as those demonstrated for granular cell tumor at common sites.
Hosaka
Tomoko
T
Department of Surgery, Sendai Kosei Hospital, Sendai, Japan.
Suzuki
Satoshi
S
Niikawa
Hiromichi
H
Shibuya
Jotaro
J
Suzuki
Takashi
T
Handa
Masashi
M
D000328:Adult; D003937:Diagnosis, Differential; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000473:pathology