A study of dermatophytes and their in-vitro antifungal sensitivity.
Of the 150 clinically suspected cases of Dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), Tinea corporis (48.7%) and Tinea capitis (18%) were the commonest clinical types. The isolation rate was 24% (36) of which 19 (52.7%) were Trichophyton rubrum, 11 (30.55%) were Trichophyton mentagrophytes and 4 (11.1%) were Trichophyton violaceum. One isolate each of Microsporum gypseum & Epidermophyton floccosum were obtained. Griseofulvin proved to be the best drug with a sensitivity of 94.4% followed by Miconazole (75% sensitive). Tolnaftate showed a sensitivity of 47.22%. For Clotrimazole only 30.55% of the isolates were sensitive.
Sumana
M N
MN
Department of Microbiology, Govt. Medical College, Mysore.
Rajagopal
V
V
D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D003881:Dermatomycoses / Q000382:microbiology; D004821:Epidermophyton / Q000187:drug effects / Q000302:isolation & purification; D005260:Female; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D007223:Infant; D008297:Male; D008825:Miconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects / Q000302:isolation & purification; D008875:Middle Aged; D014249:Trichophyton / Q000187:drug effects* / Q000302:isolation & purification
D000935:Antifungal Agents; D006118:Griseofulvin; D008825:Miconazole