title: [Kimura's disease on the hard palate in a patient from Martinique].
abstract: BACKGROUND
  We report an observation of Kimura's disease (angiolymphoid hyperplasia with eosinophilia) in a Black patient from West Indies, in a rare localisation on hard palate.
  
  
  METHODS
  A 46-year-old male patient from French West Indies (Martinique) presented with a tumor of hard palate evolving from 2 years with locoregional lymph nodes. He had a history of chronic urticaria, prurigo, rhinitis and alopecia areata. Pathological examination of the tumor was consistent with the diagnosis of Kimura's disease. Blood tests showed hypereosinophilia, elevation of IgG and IgE. The serology of Toxocara canis with Western blott was positive. Corticosteroid therapy (0.7 mg/kg/d) and albendazole (800 mg/d) allowed regression of the tumor, lymph nodes, and urticaria. The remaining tumor was surgically excised.
  
  
  CONCLUSIONS
  Kimura's disease was first described in Japanese young men, between 20 and 40 years old, with subcutaneous nodules on head and neck area. Involvement of oral mucosa is rare, and the occurence in West Indian patients has been rarely reported.
authors.affiliation: Service de médecine interne, centre hospitalier universitaire de Fort-de-France, 97261 cedex, Fort-de-France, Martinique.
authors.forename: V
authors.initials: V
authors.lastname: Ray
authors.forename: A-M
authors.initials: AM
authors.lastname: Boisseau-Garsaud
authors.forename: G
authors.initials: G
authors.lastname: Hillion
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000097:blood / Q000175:diagnosis* / Q000469:parasitology* / Q000628:therapy; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D044383:Black People; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004804:Eosinophils; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008395:Martinique; D008875:Middle Aged; D021362:Palate, Hard; D013256:Steroids; D017166:Toxocara canis; D014120:Toxocariasis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000871:Anthelmintics; D000893:Anti-Inflammatory Agents; D007074:Immunoglobulin G; D013256:Steroids; D007073:Immunoglobulin E; D015766:Albendazole
vernacular_title: Maladie de Kimura à localisation palatine chez un Antillais.