Dialysis modalities and dyslipidemia.
Progressive renal failure is accompanied by dyslipidemia, which is reflected in an abnormal apolipoprotein profile. It is characterized by increased concentrations of intact and partially metabolized triglyceride-rich apoB-containing lipoproteins. They occur preferentially in very-low density lipoprotein (VLDL) and low-density lipoprotein (LDL) as a result of impaired metabolism and clearance. Hemodialysis can moderately attenuate the renal dyslipidemia. In contrast, peritoneal dialysis is associated with further aggravation, including an increase of cholesterol-rich apoB-containing lipoproteins.
Attman
Per-Ola
PO
Department of Nephrology, Sahlgrenska University Hospital, Göteborg, Sweden. per-ola.attman@vgregion.se
Samuelsson
Ola
O
Johansson
Ann-Cathrine
AC
Moberly
James B
JB
Alaupovic
Petar
P
D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D010530:Peritoneal Dialysis; D006435:Renal Dialysis