title: Presurgical fMRI evaluation of cerebral reorganization and motor deficit in patients with tumors and vascular malformations.
abstract: The aim of this fMRI study was to evaluate the motor reorganization (cerebral plasticity) and the risk of motor deficit in patients presenting with tumors and vascular malformations, within the framework of their pre-surgical planning. Functional MR imaging data was obtained from 17 patients. Ten patients (seven with tumors and three with vascular malformations) presented with motor reorganization. The results of the present study suggest that the evaluation of the cerebral reorganization is an essential step in predicting the risk of motor deficit in patients having surgical indication for treatment. Furthermore, the cerebral reorganization constitutes an important factor for surgical decision.
authors.affiliation: Laboratoire de Psychologie Expérimentale, UMR CNRS 5105, Université Pierre Mendès-France, 151 Rue des Universités, Domaine Universitaire, 38400 Saint Martin d'Hères, Grenoble BP47, France. monica.baciu@upmf-grenoble.fr
authors.forename: M
authors.initials: M
authors.lastname: Baciu
authors.forename: J F
authors.initials: JF
authors.lastname: Le Bas
authors.forename: C
authors.initials: C
authors.lastname: Segebarth
authors.forename: A L
authors.initials: AL
authors.lastname: Benabid
mesh_terms: D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D005910:Glioma / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D009044:Motor Cortex / Q000502:physiology*; D011300:Preoperative Care