title: Candidemia in a tertiary care hospital: epidemiology and factors influencing mortality.
abstract: The present study was conducted in order to assess the epidemiology and clinical course of candidemia and to identify the risk factors associated with mortality. A total of 143 episodes of nosocomial candidemia were identified during a 5-year period, and these were included in the study. The majority of candidemic episodes were due to Candida albicans (63, 44%), followed by Candida parapsilosis(32, 22%). The overall mortality was 45%. The following independent prognostic factors for mortality were identified: bacterial sepsis, rapidly fatal illness, chronic obstructive lung disease, presence of a central venous catheter, candidemia due to Candida albicans, and lack of antifungal therapy.
authors.affiliation: Division of Preventive Medicine, University of Cantabria, School of Medicine, Santander, Spain.
authors.forename: H
authors.initials: H
authors.lastname: Alonso-Valle
authors.forename: O
authors.initials: O
authors.lastname: Acha
authors.forename: J D
authors.initials: JD
authors.lastname: García-Palomo
authors.forename: C
authors.initials: C
authors.lastname: Fariñas-Alvarez
authors.forename: C
authors.initials: C
authors.lastname: Fernández-Mazarrasa
authors.forename: M C
authors.initials: MC
authors.lastname: Fariñas
mesh_terms: D000328:Adult; D000368:Aged; D002175:Candida / Q000145:classification* / Q000302:isolation & purification; D002176:Candida albicans / Q000145:classification / Q000302:isolation & purification; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D005260:Female; D016469:Fungemia / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors