[Study on risk factors and molecular typing of Acinetobacter baummanii in nosocomial infections].
OBJECTIVE
To study the risk factors of Acinetobacter baummanii in nosocomial infections, and to verify the nature of Acinetobacter baumannii strains isolated from intensive care unit (ICU).


METHODS
A hundred and fourty patients associated with nosocomial infection of Acinetobacter baummanii from four teaching hospitals were selected and compared with controls through a case control study to identify risk factors. The strains isolated from the ICU were typed by polymerase chain reaction (PCR) with the primer M(13) following electrophoresis in agarose gel.


RESULTS
The odds ratios (ORs) were: state of the illness (OR = 8.69), using immunosuppressant (OR = 4.85), mechanical ventilation (OR = 3.68) and treatment with 3 kinds of antibiotics (OR = 3.014). Data from PCR studies indicated that these strains were sharing identical band pattern from the five strains.


CONCLUSIONS
Risk factors for nosocomial infection with Acinetobacter baummanii included state of an illness, immunosuppressant, mechanical ventilation, and treatment with antibiotics. A multidrug-resistant strains of Acinetobacter baumannii was identified in ICU.
Liu
Ding
D
Center of Nosocomial Infection, The Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Chen
Ping
P
Chen
Wei
W
Lian
Xiang-qun
XQ
Yu
Zhi-hai
ZH
D040981:Acinetobacter baumannii / Q000145:classification* / Q000235:genetics; D003428:Cross Infection / Q000209:etiology / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D016015:Logistic Models; D016133:Polymerase Chain Reaction; D012307:Risk Factors