title: Drosophila asrij is expressed in pole cells, trachea and hemocytes.
abstract: We have analysed the expression, during embryogenesis, of a Drosophila gene asrij (Sanskrit; asR ij = blood), which encodes a novel conserved protein with putative transmembrane domains. asrij is expressed in the pole cells, amnioserosa, trachea and hemocytes. Embryos homozygous for a chromosomal deficiency that removes asrij have no embryonic hemocytes. Expression in the blood-cell lineage precedes that of known hematopoietic transcription factors. These results suggest that Drosophila asrij functions in the hematopoietic lineage.
authors.affiliation: Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, 560 064, Bangalore, India. inamdar@jncasr.ac.in
authors.forename: Maneesha S
authors.initials: MS
authors.lastname: Inamdar
mesh_terms: D000818:Animals; D017931:DNA Primers; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000196:embryology* / Q000235:genetics*; D020869:Gene Expression Profiling; D006410:Hematopoiesis / Q000235:genetics*; D006434:Hemocytes / Q000502:physiology; D017403:In Situ Hybridization; D008565:Membrane Proteins / Q000235:genetics*; D014132:Trachea / Q000502:physiology
chemical_list: C570890:Asrij protein, Drosophila; D017931:DNA Primers; D029721:Drosophila Proteins; D008565:Membrane Proteins