title: Potential and limitations of the automatic detection of fiducial markers using an amorphous silicon flat-panel imager.
abstract: Amorphous silicon electronic portal imaging devices (a-Si EPIDs) allow fast acquisition of high resolution portal images (PI). A visualization of organ movement for adaptive image-guided radiotherapy (IGRT) can be reached by implantation and automatic detection of fiducial markers. A method of automatic detection has been developed for fiducial spherical tungsten markers on PIs, acquired with an a-Si flat-panel imager. The detection method consists of a 2D Mexican hat filter (MHF), whose parameters are tuned to the particular marker signal. The high selectivity of this filter allows a reliable and precise detection of tungsten markers down to a diameter of 1.5 mm. The presented method allows fast, automatic and unsupervised detection of markers. Inevitably, the detection is hampered by image background (bone structures, etc) and noise. A detection success rate higher than 95% was reached, analysing PIs of patients with markers fixed on their skin. Furthermore, this approach to automatic marker detection can also be generalized to elliptic MHFs for the detection of cylindrical markers. The accuracy and detection probability of this method may allow accurate and fast online localization of the considered organ.
authors.affiliation: Abteilung für Medizinische Physik, Universitatsklinik für Radioonkologie Tübingen, Hoppe-Seyler-Str. 3. 72076 Tübingen, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Buck
authors.forename: M
authors.initials: M
authors.lastname: Alber
authors.forename: F
authors.initials: F
authors.lastname: Nüsslin
mesh_terms: D005240:Feasibility Studies; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D019047:Phantoms, Imaging; D011471:Prostatic Neoplasms / Q000503:physiopathology / Q000532:radiotherapy; D011856:Radiographic Image Enhancement / Q000295:instrumentation* / Q000379:methods*; D011874:Radiometry / Q000295:instrumentation / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation* / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000503:physiopathology