Midazolam syrup as a premedication to reduce the discomfort associated with pediatric intravenous catheter insertion.
This randomized, double-blind, placebo-controlled study evaluated midazolam syrup for reducing discomfort from intravenous placement in children 9 months to 6 years. Parents and observers rated the child's discomfort by using visual analogue scales. Median parents' pain scores were significantly lower in the midazolam than the placebo group (P =.002). Midazolam effectively reduces discomfort associated with intravenous insertion.
McErlean
Mara
M
Department of Emergency Medicine, Albany Medical College, Albany, New York 12208, USA.
Bartfield
Joel M
JM
Karunakar
Tanuja A
TA
Whitman
Mark C W
MC
Turley
Dawn M
DM
D000284:Administration, Oral; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D008874:Midazolam / Q000008:administration & dosage* / Q000627:therapeutic use*; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D010147:Pain Measurement; D011292:Premedication; D011446:Prospective Studies
D006993:Hypnotics and Sedatives; D008874:Midazolam