title: [Effect of water-soluble vitamins on the anti-lysozyme activity of enterobacteria].
abstract: The influence of vitamins of group B (B1, B6, B12) and vitamin C on the antilysozyme activity (ALA) of pathogenic and opportunistic bacteria (Salmonella, Klebsiella, Escherichia coli) has been determined in a number of in vitro experiments. In E. coli vitamins had different influence on ALA: vitamins B1 and C (at a concentration of 5 mg/ml) increased this activity in E. coli, while vitamins B12 and C (at concentrations of 0.5 and 0.05 mg/ml) decreased it. In Klebsiella vitamins B1, B12 and C (at a concentration of 0.05 mg/ml) decreased ALA, while after the addition of vitamin C at concentrations of 0.5 and 5 mg/ml into the medium ALA increased. In Salmonella vitamins of group B had no influence on ALA, ascorbic acid at a low concentration (0.5 mg/ml) decreased their capacity for inactivating lysozyme. In enterobacteria vitamin B6 produced no changes in ALA.
authors.affiliation: Research Institute of Cellular and Intracellular Symbiosis, Medical Academy, Orenburg, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Valyshev
authors.forename: V A
authors.initials: VA
authors.lastname: Kirillov
authors.forename: D A
authors.initials: DA
authors.lastname: Kirillov
mesh_terms: D001205:Ascorbic Acid / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000378:metabolism*; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity; D007709:Klebsiella / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity; D009113:Muramidase / Q000037:antagonists & inhibitors* / Q000187:drug effects; D009894:Opportunistic Infections / Q000382:microbiology; D012475:Salmonella / Q000187:drug effects / Q000472:pathogenicity; D014803:Vitamin B Complex / Q000494:pharmacology*
chemical_list: D014803:Vitamin B Complex; D009113:Muramidase; D001205:Ascorbic Acid
vernacular_title: Vliianie vodorastvorimykh vitaminov na antilizotsimnuiu aktivnost' énterobakteriĭ.