Comparison of automated ACMIA and EMIT immunoassays for whole blood cyclosporin monitoring.
OBJECTIVE
Evaluation of a new fully automated antibody conjugated magnetic immunoassay (ACMIA) for whole blood cyclosporin (CsA) monitoring.


METHODS
Evaluation of the analytical performance of the ACMIA method and comparison to the Enzyme Multiplied Immunoassay (EMIT) method.


RESULTS
The analytical performance of the ACMIA and the EMIT methods was comparable. Without the need of a pretreatment step of the sample, the ACMIA method is faster than the EMIT method.


CONCLUSIONS
The ACMIA method for CsA monitoring is a good alternative to the EMIT method.
Dessars
Barbara
B
Department of Clinical Chemistry - Hôpital Erasme, Brussels, Belgium.
Cotton
Frédéric
F
Thiry
Philippe
P
Gulbis
Béatrice
B
D016572:Cyclosporine / Q000097:blood* / Q000276:immunology; D017248:Enzyme Multiplied Immunoassay Technique; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*
D016572:Cyclosporine