Contact dermatitis from electrocardiograph-monitoring electrodes: role of p-tert-butylphenol-formaldehyde resin.
Three cases of allergic contact dermatitis localized to the sites of electrocardiograph-monitoring electrodes are reported. All patients had positive patch tests to both the gel and the adhesive part of the Red Dot 2239 3M monitoring electrode used and to the p-tert-butylphenol-formaldehyde resin (PTBP-F-R) of the standard series. Two patients had a history of possible exposition to the resin previously but there was no explanation for the third. No information about the presence of PTBP-F-R in the electrodes could be obtained from the manufacturers. Chemical analysis of samples of the electrode, using a gas chromatography-mass spectrometry (GC-MS) and high pressure liquid chromatography (HPLC) analytical system, demonstrated the presence of several PTBP-F-R derivatives in both the gel and the adhesive part.
Avenel-Audran
M
M
Service de Dermatologie (Pr Verret), Centre Hospitalier Universitaire, Angers, France. MaAvenel-Audran@chu-angers.fr
Goossens
A
A
Zimerson
E
E
Bruze
M
M
D000269:Adhesives / Q000009:adverse effects*; D000368:Aged; D000485:Allergens / Q000009:adverse effects / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D004562:Electrocardiography / Q000009:adverse effects / Q000295:instrumentation; D015716:Electrocardiography, Ambulatory / Q000009:adverse effects* / Q000295:instrumentation; D004566:Electrodes; D005260:Female; D005500:Follow-Up Studies; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D012117:Resins, Synthetic / Q000009:adverse effects*; D012494:Sampling Studies; D012680:Sensitivity and Specificity
D000269:Adhesives; D000485:Allergens; D012117:Resins, Synthetic; C014273:p-tert-butylphenolformaldehyde resin