Abnormalities in the cerebral arterial system in osteogenesis imperfecta.
A 9-year-old girl with osteogenesis imperfecta (OI) type 4 was admitted to the hospital because of choreatic movement. Cerebral angiography demonstrated bilateral symmetrical stenosis of the proximal cavernous segment of internal carotid artery, prethrombotic occlusion of the M1 segment of left middle cerebral artery, and moyamoya-like collateral vascular structure arising from the right lenticulostriate arteries. After a literature review, these findings were interpreted as vasculopathic changes secondary to vascular fragility caused by the collagen abnormality in OI.
Albayram
Sait
S
Department of Radiology, Division of Neuroradiology, Cerrahpasa Medical School, Istanbul University, Turkey.
Kizilkilic
Osman
O
Yilmaz
Halit
H
Tuysuz
Beyhan
B
Kocer
Naci
N
Islak
Civan
C
D002198:Capillary Fragility / Q000502:physiology; D002341:Carotid Artery Thrombosis / Q000175:diagnosis / Q000235:genetics; D002343:Carotid Artery, Internal / Q000473:pathology; D002426:Cavernous Sinus / Q000473:pathology; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D007089:Image Enhancement; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000235:genetics; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis* / Q000235:genetics; D020766:Intracranial Embolism / Q000175:diagnosis / Q000235:genetics; D008279:Magnetic Resonance Imaging; D009072:Moyamoya Disease / Q000175:diagnosis / Q000235:genetics; D009460:Neurologic Examination; D010013:Osteogenesis Imperfecta / Q000175:diagnosis* / Q000235:genetics; D012307:Risk Factors