[Mechanisms of activation of pathogenic bacteria in the host organism].
A minireview of the data of literature on the interaction of bacteria with cytokins and the stimulation of the growth of pathogenic bacteria by some cytokins is presented. The addition of tumor necrosis factor-alpha into the culture medium has been shown to stimulate the growth of Salmonella virulent and avirulent strains 4-fold and 2-fold respectively. This cytokin has also been shown to produce a stimulating effect on the process of the in vitro and in vivo recultivation of noncultivating forms of virulent and avirulent strains.
Romanova
Iu M
IuM
Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
Boshnakov
R Kh
RKh
Baskakova
T V
TV
Gintsburg
A L
AL
D000818:Animals; D016207:Cytokines / Q000378:metabolism / Q000494:pharmacology; D006790:Host-Parasite Interactions / Q000187:drug effects / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007700:Kinetics; D012480:Salmonella Infections / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D012486:Salmonella typhimurium / Q000472:pathogenicity / Q000502:physiology*; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism; D015534:Trans-Activators / Q000235:genetics* / Q000276:immunology; D015533:Transcriptional Activation; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*; D014774:Virulence
D016207:Cytokines; D015534:Trans-Activators; D014409:Tumor Necrosis Factor-alpha
Mekhanizmy aktivatsii patogennykh bakteriĭ v organizme khoziaina.