title: FR235222, a fungal metabolite, is a novel immunosuppressant that inhibits mammalian histone deacetylase III. Structure determination.
authors.affiliation: Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 5-2-3, Tokodai, Tsukuba 300-2698, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Mori
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Urano
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Seiji
authors.initials: S
authors.lastname: Yoshimura
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Takase
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hino
mesh_terms: D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D056572:Histone Deacetylase Inhibitors; D007166:Immunosuppressive Agents / Q000737:chemistry* / Q000494:pharmacology; D008958:Models, Molecular; D008968:Molecular Conformation; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004791:Enzyme Inhibitors; C474179:FR 235222; D056572:Histone Deacetylase Inhibitors; D007166:Immunosuppressive Agents; D010456:Peptides, Cyclic