title: Paraoxonase and other coronary risk factors in a community-based cohort.
abstract: Oxidative damage to circulating lipids and vascular tissues contributes to the initiation and progression of atherosclerosis. High density lipoprotein provides protection from atherosclerosis and the enzyme paraoxonase may contribute to this effect. The aim of the present study was to examine the trends in paraoxonase activity during the course of a community-directed life-style intervention, and relationships of paraoxonase activity to other coronary heart disease risk factors, in a cohort of Australian Aboriginal people.
authors.affiliation: Department of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
authors.forename: Jacob
authors.initials: J
authors.lastname: Cohen
authors.forename: Alicia J
authors.initials: AJ
authors.lastname: Jenkins
authors.forename: Connie
authors.initials: C
authors.lastname: Karschimkus
authors.forename: Su
authors.initials: S
authors.lastname: Qing
authors.forename: Chee Teik
authors.initials: CT
authors.lastname: Lee
authors.forename: Kerin
authors.initials: K
authors.lastname: O'Dea
authors.forename: James D
authors.initials: JD
authors.lastname: Best
authors.forename: Kevin G
authors.initials: KG
authors.lastname: Rowley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D043303:Aryldialkylphosphatase; D001315:Australia; D002265:Carboxylic Ester Hydrolases / Q000097:blood; D002338:Carotenoids / Q000097:blood; D015331:Cohort Studies; D048909:Diabetes Complications; D004032:Diet; D004950:Esterases / Q000097:blood*; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000378:metabolism; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking
chemical_list: D008075:Lipoproteins, HDL; D002338:Carotenoids; D004950:Esterases; D002265:Carboxylic Ester Hydrolases; C019734:arylesterase; D043303:Aryldialkylphosphatase