title: Elevated anticardiolipin antibodies in acute liver failure.
abstract: Antibodies to cardiolipin (aCLA), a phospholipid primarily localized in inner mitochondrial membranes, were transiently elevated (P<0.01) when mice were exposed to an industrial surfactant and then infected with influenza B virus, a model of acute liver failure (ALF). Children with ALF also had elevated levels of aCLA.
authors.affiliation: Department of Microbiology and Immunology, Dalhousie University, Nova Scotia, B3H 4H7, Halifax, Canada.
authors.forename: K R
authors.initials: KR
authors.lastname: Rozee
authors.forename: P
authors.initials: P
authors.lastname: Acott
authors.forename: S H S
authors.initials: SH
authors.lastname: Lee
authors.forename: J F S
authors.initials: JF
authors.lastname: Crocker
authors.forename: D
authors.initials: D
authors.lastname: Gough
authors.forename: J
authors.initials: J
authors.lastname: MacDonald
authors.forename: J
authors.initials: J
authors.lastname: Evans
authors.forename: M G
authors.initials: MG
authors.lastname: Murphy
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D017153:Antibodies, Anticardiolipin / Q000097:blood*; D002308:Cardiolipins / Q000276:immunology*; D002648:Child; D004195:Disease Models, Animal; D006801:Humans; D008099:Liver / Q000473:pathology / Q000648:ultrastructure; D017114:Liver Failure, Acute / Q000097:blood / Q000276:immunology* / Q000473:pathology; D051379:Mice
chemical_list: D017153:Antibodies, Anticardiolipin; D002308:Cardiolipins