title: Cooperation between memory systems: acetylcholine release in the amygdala correlates positively with performance on a hippocampus-dependent task.
abstract: The present experiment examined the relationship between release of acetylcholine (ACh) in the amygdala and performance on a hippocampus-dependent spatial working memory task. Using in vivo microdialysis, the authors measured ACh release in rats during testing on a spontaneous alternation task. Amygdala ACh release was positively correlated with performance on the hippocampus-dependent task. These findings suggest that activation of the amygdala promotes processing in other neural systems important for learning and memory.
authors.affiliation: Department of Neurobiology and Behavior, University of California, Irvine, USA.
authors.forename: Christa K
authors.initials: CK
authors.lastname: McIntyre
authors.forename: Lisa K
authors.initials: LK
authors.lastname: Marriott
authors.forename: Paul E
authors.initials: PE
authors.lastname: Gold
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000679:Amygdala / Q000378:metabolism*; D000818:Animals; D005106:Exploratory Behavior / Q000502:physiology; D006624:Hippocampus / Q000378:metabolism* / Q000502:physiology; D008297:Male; D018782:Maze Learning / Q000502:physiology; D008568:Memory / Q000502:physiology*; D017551:Microdialysis; D011597:Psychomotor Performance / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000109:Acetylcholine