Polysiloxane-supported NAD(P)H model 1-benzyl-1,4-dihydronicotinamide: synthesis and application in the reduction of activated olefins.
A new polysiloxane-supported NAD(P)H model, 1-benzyl-1,4-dihydronicotinamide, was designed and synthesized, which can efficiently reduce many activated olefins under mild conditions. The most advantageous features of this new polysiloxane-supported reductant are (i) easy workup and separation of the reaction products and (ii) good potential for recycling use of the reductant, which makes this new polysiloxane-supported NAD(P)H model a promising alternative both in research laboratories and in industrial processes.
Zhang
Baolian
B
State Key Laboratory of Elemento-Organic Chemistry, Department of Chemistry, Nankai University, Tianjin 300071, China.
Zhu
Xiao-Qing
XQ
Lu
Jin-Yong
JY
He
Jiaqi
J
Wang
Peng G
PG
Cheng
Jin-Pei
JP
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D009243:NAD / Q000031:analogs & derivatives*; D009249:NADP; D010084:Oxidation-Reduction; D012833:Siloxanes / Q000737:chemistry
C445701:1-benzyl-1,4-dihydronicotinamide; D000475:Alkenes; D012833:Siloxanes; D009243:NAD; D009249:NADP