Evaluation of preservative systems in a sunscreen formula by linear regression method.
A sunscreen formula with eight different preservative systems was evaluated by linear regression, pharmacopeial, and the CTFA (Cosmetic, Toiletry and Fragrance Association) methods. The preparations were tested against Staphylococcus aureus, Burkholderia cepacia, Shewanella putrefaciens, Escherichia coli, and Bacillus sp. The linear regression method proved to be useful in the selection of the most effective preservative system used in cosmetic formulation.
Bou-Chacra
Nádia A
NA
Department of Pharmacy, Faculty of Pharmaceutical Sciences, São Paulo University, São Paolo, Brazil.
Pinto
Terezinha de Jesus A
Tde J
Ohara
Mitsuko Taba
MT
D000890:Anti-Infective Agents / Q000494:pharmacology / Q000592:standards*; D015169:Colony Count, Microbial; D016014:Linear Models; D008826:Microbial Sensitivity Tests; D013473:Sunscreening Agents / Q000737:chemistry*
D000890:Anti-Infective Agents; D013473:Sunscreening Agents