Anti-E alloimmunization in pregnancy: management dilemmas.
Compared to anti-D alloimmunization, anti-E alloimmunization is a less common cause of hemolytic diseases of the newborn. Being a less potent immunogen, clinical manifestations of anti-E alloimmunization are more variable and usually of less severity. However, the clinical obstetric management of these cases of anti-E alloimmunization is just as challenging. We report here the management of a patient with anti-E alloimmunization to illustrate the controversies of invasive and non-invasive monitoring in the management of such cases.
To
William W K
WW
Department of Obstetrics and Gynaecology, United Christian Hospital, Kwun Tong, Kowloon, Hong Kong. wwkto@hutchcity.com
Ho
San-Ni
SN
Mok
Ka Ming
KM
D000017:ABO Blood-Group System / Q000276:immunology; D000328:Adult; D000649:Amniocentesis; D003937:Diagnosis, Differential; D004899:Erythroblastosis, Fetal / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis*; D011247:Pregnancy; D011295:Prenatal Care; D016216:Ultrasonography, Prenatal
D000017:ABO Blood-Group System; D007518:Isoantibodies