title: Solution crystallisation via a submerged liquid-liquid phase boundary: oiling out.
abstract: In many situations the process of crystallisation from solution is known to occur via metastable crystalline states (polymorphs or solvates). Here we present what we believe to be a novel example of small molecule crystallisation in which the initial separation of a solute rich liquid phase precedes the crystallisation event. We believe this occurs because a submerged liquid-liquid phase boundary is accessible within the metastable zone of the crystal nucleation process.
authors.affiliation: Process Studies Group, Syngenta, Huddersfield, West Yorkshire, UK HD2 1FF.
authors.forename: P E
authors.initials: PE
authors.lastname: Bonnett
authors.forename: K J
authors.initials: KJ
authors.lastname: Carpenter
authors.forename: S
authors.initials: S
authors.lastname: Dawson
authors.forename: R J
authors.initials: RJ
authors.lastname: Davey