title: Ethics of large clinical trials in rapidly lethal diseases.
authors.forename: Simon
authors.initials: S
authors.lastname: Rule
authors.forename: Adrian
authors.initials: A
authors.lastname: Copplestone
mesh_terms: D002986:Clinical Trials as Topic / Q000941:ethics*; D017322:Clinical Trials, Phase II as Topic; D004345:Drug Industry; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy; D018401:Sample Size; D019452:Terminally Ill