Splenic spontaneous rupture (SSR) and hemoperitoneum associated with low molecular weight heparin: a case report.
We describe the first case of spontaneous splenic rupture associated with tinzaparin in a cancer patient. This low-molecular-weight heparin was administrated for deep venous thrombosis and pulmonary embolism. No underlying splenic pathology predisposing to this condition was found.
Taccone
Fabio Silvio
FS
Service de Soins Intensifs (ASTI), Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Rue Heger-Bordet 1, 1000 Brussels, Belgium.
Starc
Jean-Marc
JM
Sculier
Jean-Paul
JP
D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006465:Hemoperitoneum / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology; D011655:Pulmonary Embolism / Q000188:drug therapy; D011859:Radiography; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013997:Time Factors; D000078222:Tinzaparin; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D000078222:Tinzaparin