title: [Clinical course of epidermoid carcinoma of the penis in our series].
abstract: OBJECTIVE
  To study the evolution of 49 patients with squamous cell carcinoma of the penis.
  
  
  METHODS
  49 patients who underwent surgery for squamous cell carcinoma of the penis (30 partial penile amputations, 11 total amputations and 7 circumcisions). 27 inguinal lymphadenectomies, superficial, profound and ilio-obturator (2 cases), were performed due to persistent lymph nodes after penile amputation despite of antibiotic treatment for 4 weeks, or to high grade primary tumour. 13 patients were found to have lymph node metastases after treatment, receiving posterior adjuvant treatment with radiotherapy, chemotherapy or a combination of them. Patients were followed in relation to stage, cell differentiation degree, and presence or absence of positive lymph nodes and distant metastases.
  
  
  RESULTS
  There were 5 Ta stage tumours, 26 T1(63.2%), 16 T2 (32.6%), and 2 T3 (4.08%). Regarding cytological degree 81% were GI, 16% G II, and 2% G III. Lymph node metastasis were detected in 13 patients (26.53%) after lymph node dissection. 6 patients died from tumour dissemination, 2 of them were T2G2, one T2G1, and three T1G2; two additional patients died from causes different from the tumour, all of them being N+ at the time of diagnosis.
  
  
  CONCLUSIONS
  Penile squamous cell carcinoma is an aggressive tumour the evolution of which mainly depends on the local-regional stage at the time of diagnosis and cell differentiation; these factors will condition lymphadenectomy versus observation.
authors.affiliation: Servicio de Urología I, Hospital Central de Asturias, Oviedo, España.
authors.forename: Jorge
authors.initials: J
authors.lastname: García Rodríguez
authors.forename: Jesús María
authors.initials: JM
authors.lastname: Fernández Gómez
authors.forename: Juan Javier
authors.initials: JJ
authors.lastname: Rodríguez Martínez
authors.forename: Oscar
authors.initials: O
authors.lastname: Rodríguez Faba
authors.forename: Antonio
authors.initials: A
authors.lastname: Jalón Monzón
authors.forename: Alfonso
authors.initials: A
authors.lastname: San Martín Blanco
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Martínez Gómez
authors.forename: Alberto
authors.initials: A
authors.lastname: Sánchez Trilla
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Martín Benito
authors.forename: Safwan
authors.initials: S
authors.lastname: Escaf Barmadah
authors.forename: Javier
authors.initials: J
authors.lastname: Regadera Sejas
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000473:pathology* / Q000601:surgery*
vernacular_title: Análisis de la evolución del carcinoma epidermoide de pene en nuestra serie.