[Studies on 14 functional foods labelled with tumor inhibition effects].
Tumor inhibition effects of 14 functional foods were measured. Test items included sarcoma 180(S180) inhibiting test, Ehrlich ascites carcinoma (EAC) inhibiting test, phagocyte phagocytosis test and NK cell activity test. The results showed dose-response tendencies in all indices. But the tumor inhibition rate and survival time were decreased in high dose groups and even lower than those of control group (P < 0.05) in some samples. Correlation analysis showed a positive correlation between tumor inhibition rate and survival time, phagocytic percentage and phagocytic index, phagocytic percentage and NK activity, phagocytic index and NK activity (P < 0.01). Tumor inhibition rate and phagocytic percentage appeared negative correlation (P < 0.05). It is suggested that the present methods should be modified. The new and better methods needed to be established. The judge criterion for functional food should be strictly enacted. More Studies needed to be repeated for some foods with significant tumor inhibition functions.
Dai
Q
Q
Institute of Nutrition and Functional Foods, Medical College, Shanghai Tiedao University, Shanghai 200070, China.
Li
S
S
Yu
J
J
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology; D019587:Dietary Supplements; D007694:Killer Cells, Natural / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D010587:Phagocytosis / Q000187:drug effects; D012510:Sarcoma 180 / Q000276:immunology
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents