title: Effect of iron on growth in iron deficient anemic school going children.
abstract: Iron deficiency anemia (IDA) in children has been associated with retardation in growth and the cognitive development. In the ongoing study on the effects of IDA in school going children, the effects on anthropometric parameters such as height (Ht), Weight (Wt), head circumference (HC), body mass index (BMI) and the mid arm circumference (MAC) were studied along with the hematological parameters such as hemoglobin (Hb), hematocrit (Hct), MCV, MCH, serum iron (SI), total iron binding capacity (TIBC) and % saturation. The pre-supplementation values of all these parameters were taken in anemic and control groups of girls and boys. After deworming all the children with albendazole (400 mg), the anemic group was put on iron supplementation (Ferrous iron 3-4 mg/kg body weight/day) along with vitamin C (100 mg OD) and the control children were given vitamin C (100 mg OD), for 90 days. Pre-supplementation values of IDA children were significantly lower for MAC and HC in girls and for Ht and MAC in boys, when compared to the control group. After the therapy both the groups of girls showed improvement in the hematological parameters though it was greater in the anemic girls. Ht and Wt of both groups also improved significantly but the anemic girls showed increase in BMI also. Both the control and anemic boys showed gain in weight. Post therapy, improvement in hematological parameters for both the anemic girls and boys were greater than their respective control groups. The MAC value for anemic girls were in the control range but those of anemic boys remained lesser than the control boys. So, it can be concluded from the present study that the IDA children lagged behind the control children in terms of anthropometric parameters and they benefited relatively more in terms of anthropometric improvement and hematological improvement after iron supplementation.
authors.affiliation: Department of Physiology, University College of Medical Sciences & Guru Teg Bahadur Hospital, Dilshad Garden, Delhi-110 095.
authors.forename: R
authors.initials: R
authors.lastname: Bandhu
authors.forename: N
authors.initials: N
authors.lastname: Shankar
authors.forename: O P
authors.initials: OP
authors.lastname: Tandon
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000188:drug therapy*; D001827:Body Height / Q000187:drug effects* / Q000502:physiology; D001835:Body Weight / Q000187:drug effects / Q000502:physiology; D002648:Child; D005260:Female; D006801:Humans; D007501:Iron / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D013334:Students / Q000706:statistics & numerical data
chemical_list: D007501:Iron