GoMiner: a resource for biological interpretation of genomic and proteomic data.
We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative and statistical output files and two useful visualizations. The first is a tree-like structure analogous to that in the AmiGO browser and the second is a compact, dynamically interactive 'directed acyclic graph'. Genes displayed in GoMiner are linked to major public bioinformatics resources.
Zeeberg
Barry R
BR
Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Feng
Weimin
W
Wang
Geoffrey
G
Wang
May D
MD
Fojo
Anthony T
AT
Sunshine
Margot
M
Narasimhan
Sudarshan
S
Kane
David W
DW
Reinhold
William C
WC
Lababidi
Samir
S
Bussey
Kimberly J
KJ
Riss
Joseph
J
Barrett
J Carl
JC
Weinstein
John N
JN
D003196:Computer Graphics; D003627:Data Interpretation, Statistical; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D023281:Genomics; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D040901:Proteomics; D012984:Software; D012985:Software Design