[Soluble interleukin 2 receptor (SIL-2R) in bronchoalveolar lavage fluid (BALF) of patients with sarcoidosis and atopic bronchial asthma].
The aim of the study was assessment of sIL-2R in BALF in asthma and sarcoidosis patients. Forty three patients were enrolled in this study. Twenty eight with sarcoidosis (S) in different stages (I, II, III) and activity of disease: active (AS) or nonactive (NAS) and fifteen with atopic bronchial asthma (AO). BALF sIL-2R levels were measured in both groups. The level of sIL-2R was similar in sarcoidosis patients independently to activity of disease. Significantly lower level of sII-2R in BALF was observed in patients with AO in comparison to S, SII and NAS (p < 0.005). We didn't find significant differences in sIL-2R levels between AO and SI, SIII, AS.
Jankowska
Renata
R
Katedra i Klinika Chorób Płuc AM, Wrocławiu.
Passowicz-Muszyńska
Ewa
E
Gołecki
Marcin
M
Krasnowska
Maryla
M
D000328:Adult; D001249:Asthma / Q000276:immunology / Q000378:metabolism*; D015415:Biomarkers / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry* / Q000276:immunology; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D017565:Sarcoidosis, Pulmonary / Q000276:immunology / Q000378:metabolism*; D012995:Solubility; D018709:Statistics, Nonparametric
D015415:Biomarkers; D015375:Receptors, Interleukin-2
Rozpuszczalny receptor dla interleukiny 2 w popłuczynach oskrzelowo--pecherzykowych (BALF) u chorych na sarkoidoze i astme oskrzelowa atopowa.