Guillain-Barré syndrome associated with immune reconstitution.
We report a case of acute Guillain-Barré syndrome (GBS) associated with a prompt and vigorous immune reconstitution and decrease in the virus load noted during treatment with a potent regimen of highly active antiretroviral therapy. We hypothesize that GBS may have been due to an aberrant immune response or an adverse drug reaction in association with preexisting peripheral neurologic disease.
Piliero
Peter J
PJ
Albany Medical College, Albany, New York 12208, USA. pilierp@mail.amc.edu
Fish
Douglas G
DG
Preston
Sandra
S
Cunningham
Donna
D
Kinchelow
Tosca
T
Salgo
Miklos
M
Qian
Jiang
J
Drusano
George L
GL
D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D020275:Guillain-Barre Syndrome / Q000209:etiology / Q000276:immunology*; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D007109:Immunity / Q000187:drug effects; D008297:Male; D008875:Middle Aged
D019380:Anti-HIV Agents