title: [Expression of adhesion molecules LFA-1 and L-selectin on PMN and level of soluble sE-selectin and sL-selectin in the serum of patients with small cell lung cancer].
abstract: The aim of this study was to estimate expression of adhesion molecules LFA-1 and L-selectin on PMN of peripheral blood, and level of soluble sE-selectin and sL-selectin in the serum of 16 patients with small cell lung cancer (SCLC) before treatment. We observed significantly higher expression of LFA-1 and L-selectin on PMN in comparison to healthy persons and higher level sE selectin and sL selectin in the serum of SCLC patients. Increasing of adhesion molecules expression on PMN can lead to damage of neoplasmatic cells and may be one of the reasons for create a new cancer sites as well.
authors.affiliation: Zakład Immunologii AM, Białymstoku. anetaiz@mp.pl
authors.forename: Aneta
authors.initials: A
authors.lastname: Izycka
authors.forename: Ewa
authors.initials: E
authors.lastname: Jabłońska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Izycki
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Chyczewska
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000276:immunology*; D016022:Case-Control Studies; D002448:Cell Adhesion; D019040:E-Selectin / Q000097:blood*; D005260:Female; D006801:Humans; D019041:L-Selectin / Q000097:blood*; D008175:Lung Neoplasms / Q000276:immunology*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D018709:Statistics, Nonparametric
chemical_list: D019040:E-Selectin; D016169:Lymphocyte Function-Associated Antigen-1; D019041:L-Selectin
vernacular_title: Ocena ekspresji czasteczek adhezyjnych LFA-1 i L-selektyny na neutrofilach krwi obwodowej oraz poziomu rozpuszczalnych form L-selektyny i E-selektyny u chorych na drobnokomórkowego raka płuca.