title: Direct catalytic asymmetric aldol-type reaction of aldehydes with ethyl diazoacetate.
abstract: The direct aldol-type condensation of aldehydes with ethyl diazoacetate catalyzed by the chiral complex of BINOL derivatives-Zr(O(t)Bu)(4) gave beta-hydroxy alpha-diazo carbonyl compounds with moderate enantioselectivities (53-87% ee). [reaction: see text]
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry, Peking University, Beijing 100871, People's Republic of China.
authors.forename: Wengang
authors.initials: W
authors.lastname: Yao
authors.forename: Jianbo
authors.initials: J
authors.lastname: Wang