Acute toxicity of some heavy metals to Lates calcarifer fry with a note on its histopathological manifestations.
Static bioassay tests for acute toxicity of four heavy metals to fry of the fish Lates calcarifer in brackishwater medium were conducted. The 96 h LC50 values of metals such as Hg, Cu, Cr, and Mn for two different size groups 11 +/- 3 mm and 24 +/- 4 mm were found to be 0.085, 1.3, 27.9, and 220 mg/L and 0.20, 1.8, 33, and 250 mg/L, respectively. The rank order of toxicity of metals was found to be Hg > Cu > Cr > Mn. Using the safe concentration factor of 0.01, the allowable safe concentration for Hg, Cu, Cr, and Mn in brackishwater are 0.00085-0.002, 0.013-0.018, 0.279-0.33, and 2.20-2.50 mg/L, respectively. The damage caused to different organ systems of the fish, exposed to the heavy metals, agrees with the rank order of the toxicity. Heavy nerve tissue necrosis was observed in fish exposed to mercury. Copper induced gill epithelial necrosis and kidney tubular degeneration. Chromium and manganese accounted for various histopathological manifestations involving vital organs such as liver and kidney.
Krishnani
K K
KK
Central Institute of Brackishwater Aquaculture, R.A. Puram, Chennai, India. krishnanik@hotmail.com
Azad
Ismail S
IS
Kailasam
M
M
Thirunavukkarasu
A R
AR
Gupta
B P
BP
Joseph
K O
KO
Muralidhar
M
M
Abraham
Mathew
M
D000818:Animals; D005880:Gills / Q000473:pathology; D007668:Kidney / Q000473:pathology; D007814:Larva; D007928:Lethal Dose 50; D008099:Liver / Q000473:pathology; D019216:Metals, Heavy / Q000633:toxicity*; D009336:Necrosis; D009420:Nervous System / Q000473:pathology; D010473:Perciformes / Q000502:physiology*; D014873:Water Pollutants / Q000633:toxicity*
D019216:Metals, Heavy; D014873:Water Pollutants