title: Immunohistochemical assays of farnesyltransferase inhibition in patient samples.
authors.affiliation: Department of Oncology, Mayo Clinic and Foundation, Rochester, MN, USA.
authors.forename: Alex A
authors.initials: AA
authors.lastname: Adjei
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002352:Carrier Proteins / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D034904:Lamin Type A / Q000276:immunology / Q000378:metabolism*; D051379:Mice; D008969:Molecular Sequence Data; D009061:Mouth Mucosa / Q000201:enzymology; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009369:Neoplasms / Q000201:enzymology*; D009687:Nuclear Proteins / Q000276:immunology; D009928:Organ Specificity; D010446:Peptide Fragments / Q000276:immunology; D011498:Protein Precursors / Q000276:immunology; D017368:Protein Prenylation / Q000187:drug effects; D011499:Protein Processing, Post-Translational / Q000187:drug effects*; D011817:Rabbits; D012680:Sensitivity and Specificity
chemical_list: D000970:Antineoplastic Agents; D002352:Carrier Proteins; C107481:DNAJA1 protein, human; D004791:Enzyme Inhibitors; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D034904:Lamin Type A; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D010446:Peptide Fragments; D011498:Protein Precursors; C090764:prelamin A; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase