title: Comparison of conventional versus wavefront-guided laser in situ keratomileusis in the same patient.
abstract: OBJECTIVE
  To verify whether there is any difference in visual outcome, including higher order aberrations, after performing laser in situ keratomileusis (LASIK) with conventional ablation and wavefront-guided ablation in myopic eyes of the same patient.
  
  
  METHODS
  This was a prospective randomized study of 20 myopic eyes (10 patients) who had LASIK using the Nidek NAVEX excimer laser system. Wavefront-guided customized ablation was used in the first eye of the patient (study group) and the other eye of the same patient was operated with conventional ablation (control group). Mean refractive error was similar between left and right eyes of the same patient. Preoperative examination included higher order aberration by Nidek OPD-Scan. Uncorrected and best spectacle-corrected visual acuity and higher order aberrations were recorded postoperatively.
  
  
  RESULTS
  Preoperative and postoperative best spectacle-corrected visual acuity was better than 20/40 (100%) after LASIK in both the conventional ablation and wavefront-guided customized ablation groups. Postoperative refraction was within +/- 0.50 D of emmetropia: 90% in the conventional group and 100% in the wavefront-guided group. No statistically significant difference in postoperative higher order aberrations was found between groups.
  
  
  CONCLUSIONS
  Postoperative visual outcome with both conventional LASIK and wavefront-guided customized ablation was not significantly different. Higher order aberrations did not significantly increase postoperatively in either group.
authors.affiliation: Laser Vision LASIK Center, Bangkok, Thailand.
authors.forename: Nutharin
authors.initials: N
authors.lastname: Phusitphoykai
authors.forename: Tulaya
authors.initials: T
authors.lastname: Tungsiripat
authors.forename: Janpen
authors.initials: J
authors.lastname: Siriboonkoom
authors.forename: Anun
authors.initials: A
authors.lastname: Vongthongsri
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D003315:Cornea / Q000601:surgery; D019781:Corneal Topography; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity