[Myocardial infarction in hiv patients treated with protease inhibitors: report of two cases].
The Authors describe two cases of HIV patients treated with Protease Inhibitors that have gone on to suffer from lipodystrophy, metabolic disorder, diabetes and myocardial infarction (fatal in one of them). The surviving patient underwent a Percutaneous Transluminal Coronary Angioplasty (PTCA) with improvement of the acute coronary syndrome. In the light of the review of literature and our observations, we propose some considerations about prevention, diagnostic and therapeutic management of HIV patients treated with IP and cardiovascular risk.
Sabbatani
Sergio
S
Unità Operativa di Malattie Infettive, Ospedale Maggiore, Bologna, Italy.
Dentale
Nicola
N
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D017809:Fatal Outcome; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*; D011480:Protease Inhibitors / Q000009:adverse effects*
D011480:Protease Inhibitors
Considerazioni su due casi di infarto miocardico in pazienti HIV positivi trattati con inibitori delle proteasi.