[Effect of auxiliary heterotopic partial liver transplantation on the pig with acute ischemic liver failure].
OBJECTIVE
To study the effect of auxiliary heterotopic partial liver transplantation on the pig with acute ischemic liver failure.


METHODS
When portal vein was shrinked more than 85 percent and artery was ligated or reserved, auxiliary heterotopic partial liver transplantation was performed in the pigs. The living condition, liver function, blood supply, pathological change and bile secretion of donor liver were observed, analysed and summarized.


RESULTS
In the artery-ligated pigs, the volume of original liver reduced and the hepatocytes were necrotic evidently. While in the artery-reserved pigs, the colour and hepatocytes of original liver were normal. The volume of donor liver augmented, and the hepatocytes lived and proliferated well.


CONCLUSIONS
Liver artery-ligated and portal vein-shrinker can result in acute ischemic liver failure, and auxiliary heterotopic partial liver transplantation is effective to treat this liver failure. reducing portal vein blood supply is little harmful to liver.
Yi
Yong-xiang
YX
Department of Pathology, Affiliated Nanjing Second Hospital, Medical College of Southeast University, Nanjing 210003, China.
Yu
Jian-guang
JG
D000818:Animals; D005260:Female; D007511:Ischemia / Q000601:surgery; D017114:Liver Failure, Acute / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D013552:Swine; D016042:Transplantation, Heterotopic / Q000379:methods