title: Synergism in mixtures of cymoxanil and mancozeb on Phytophthora infestans in vivo.
abstract: The preventive activity of 1:8 mixture of cymoxanil and mancozeb against Phytophthora infestans was higher than that of either the two single ingredients or the other nine mixtures. The synergistic interaction existed (synergy ratio 2.01) between the two at the mixing ratio of 1:8, whereas additive interaction (synergy ratios ranged from 0.73 to 1.34) existed at the mixing ratios ranging from 1:1 to 1:7, from 1:9 to 1:10, 1:8 was the optimal ratio. The preventive activity of 1:8 mixture was higher than the curative and the eradicative. In addition, the eradicative synergism of inhibiting sporangia production on lesions was stronger than the eradicative synergism of inhibiting lesion extension and suppressing infection of sporangia, and than the curative synergism of inhibiting lesion sporulation on detached potato leaflets.
authors.affiliation: Plant Protection Institute, Hebei Academy of Agricultural & Forestry Sciences, Baoding 071000, Hebei, China. wenqiaow@heinfo.net
authors.forename: Wen-Qiao
authors.initials: WQ
authors.lastname: Wang
authors.forename: Xiu-Ying
authors.initials: XY
authors.lastname: Han
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Zhang
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Kang
authors.forename: Shu-Long
authors.initials: SL
authors.lastname: Chen
mesh_terms: D000081:Acetamides / Q000008:administration & dosage / Q000633:toxicity*; D004357:Drug Synergism; D005659:Fungicides, Industrial / Q000008:administration & dosage / Q000633:toxicity*; D008344:Maneb / Q000008:administration & dosage / Q000633:toxicity*; D010838:Phytophthora / Q000187:drug effects*; D011198:Solanum tuberosum / Q000382:microbiology; D015038:Zineb / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D000081:Acetamides; D005659:Fungicides, Industrial; D008344:Maneb; C025644:2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide; C013099:mancozeb; D015038:Zineb