title: Iron-catalyzed regio- and stereoselective ring opening of [2.2.1]- and [3.2.1]oxabicyclic alkenes with a Grignard reagent.
abstract: [reaction: see text] Arylative and alkenylative ring-opening reactions of a [2.2.1]- or [3.2.1]oxabicyclic alkene with a Grignard reagent take place in the presence of a catalytic amount of iron(III) chloride and a stoichiometric amount of TMEDA to produce a highly substituted 3-cyclohexen-1-ol or 3-cyclohepten-1-ol in good yield with high regio- and stereoselectivity.
authors.affiliation: Department of Chemistry, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. nakamura@chem.s.u-tokyo.ac.jp
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Keiko
authors.initials: K
authors.lastname: Matsuo
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Inoue
authors.forename: Eiichi
authors.initials: E
authors.lastname: Nakamura