Severe proliferative retinopathy progressing to blindness in a japanese woman with takayasu disease.
OBJECTIVE
To report a patient with Takayasu disease with severe proliferative retinopathy progressing to bilateral blindness. A 57-year-old Japanese woman suffering from Takayasu disease for 16 years manifested severe proliferative retinopathy in both eyes, leading to blindness due to optic atrophy.


METHODS
Interventional case report.


METHODS
A 57-year-old Japanese woman suffering from Takayasu disease for 16 years underwent a comprehensive opthalmologic examination. Panretinal photocoagulation and vitrectomy were performed on both eyes.


METHODS
Institutional practice.


RESULTS
At initial examination, the patient was found to have severe proliferative retinopathy with tractional retinal detachment in both eyes. The retinal detachments were repaired by the vitrectomy, however, the patient developed bilateral blindness due to optic atrophy.


CONCLUSIONS
Patients with a long history of Takayasu disease can demonstrate severe proliferative retinopathy that may be resistant to photocoagulation and/or vitreous surgery. Ocular ischemia can lead to blindness from ischemic optic neuropathy.
Kuwahara
Chihiro
C
Department of Ophthalmology, Osaka Medical College, Japan.
Imamura
Yutaka
Y
Okamura
Nobuaki
N
Sakai
Ryouichi
R
Ikeda
Tsunehiko
T
D001766:Blindness / Q000209:etiology*; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007564:Japan; D017075:Laser Coagulation; D008875:Middle Aged; D009896:Optic Atrophy / Q000209:etiology; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013625:Takayasu Arteritis / Q000150:complications* / Q000175:diagnosis / Q000208:ethnology; D014821:Vitrectomy