Variability in phenolic composition of Hypericum androsaemum.
The methanolic extracts of fifteen Hypericum androsaemum samples, growing spontaneously or cultivated in Portugal, were analysed by HPLC/DAD, allowing the identification of 9 phenolic compounds and the detection of 6 phloroglucinols. Total amounts of phenolics found ranged from 11 to 39 g/kg, and the influence of some factors which may be responsible for this variation is discussed. The individual compounds were also quantified. Four different phenolic profiles were found concerning both qualitative and quantitative composition, indicating the possible existence of chemical polymorphism.
Valentão
Patrícia
P
CEQUP/Serviço de Farmacognosia, Faculdade de Farmácia, Universidade do Porto, R. Anibal Cunha 164, 4050-047 Porto, Portugal.
Dias
Alberto
A
Ferreira
Manuel
M
Silva
Branca
B
Andrade
Paula B
PB
Bastos
M Lourdes
ML
Seabra
Rosa M
RM
D002851:Chromatography, High Pressure Liquid; D006801:Humans; D020902:Hypericum; D010636:Phenols / Q000737:chemistry*; D010696:Phloroglucinol / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves
D010636:Phenols; D010936:Plant Extracts; D010696:Phloroglucinol