Hypertrophic pachymeningitis: case report.
Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.
de Deus-Silva
Leonardo
L
University of Campinas, Campinas, SP, Brazil.
Queiroz
Luciano de Souza
Lde S
Zanardi Vd
Verônica de Araújo
Vde A
Ghizoni
Enrico
E
Pereira
Hoyama da Costa
Hda C
Malveira
George Linard Silva
GL
Pirani
Clodoaldo
C
Damasceno
Benito Pereira
BP
Cendes
Fernando
F
D001706:Biopsy; D004388:Dura Mater / Q000473:pathology; D005260:Female; D005682:Gadolinium; D006801:Humans; D006984:Hypertrophy; D018810:Magnetic Resonance Angiography; D008581:Meningitis / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D009300:Nasal Septum / Q000473:pathology; D009901:Optic Nerve Diseases / Q000150:complications
D005682:Gadolinium