[Prognostic significance of factors of membrane pathology in hypertension].
A rise in cell concentration of calcium, magnitude of its increment in response to stimulation, activity of proteinkinase C, and membrane content of actin have been shown to affect the complication rates in hypertensive disease (HD). A correlation has been established between the incidence of complications and membrane disorders in irregular intake of enalapril, its regular administration having been associated with a lower fatality rate and fewer complications in HD patients.
Babadzhan
V D
VD
D000199:Actins / Q000378:metabolism; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D002118:Calcium / Q000037:antagonists & inhibitors; D004656:Enalapril / Q000008:administration & dosage / Q000627:therapeutic use; D004910:Erythrocyte Membrane / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology*; D011379:Prognosis; D011493:Protein Kinase C / Q000378:metabolism
D000199:Actins; D000959:Antihypertensive Agents; D004656:Enalapril; D011493:Protein Kinase C; D002118:Calcium
Prognosticheskoe znachenie disbalansa membrannykh faktorov pri gipertonicheskoĭ bolezni.