Efficient adsorption of the mycotoxins zearalenone and T-2 toxin on a modified yeast glucan.
1,3-Beta-D-glucan derived from baker's yeast was chemically modified in two steps yielding crosslinked carboxymethyl glucan as the sodium salt (2). After cation exchange with hexadecyltrimethylammonium chloride, a hydrophobic adsorbent (3) was obtained which showed an excellent binding of the estrogenic mycotoxin zearalenone with a maximum adsorption of up to 183 mg/g. Compound 3 additionally showed a relatively high adsorption capacity for the trichothecene T-2 toxin of at least 10 mg/g. Starting from 2, various derivatives were prepared by cation exchange using quaternary ammonium salts bearing substituents besides methyl from four to 18 carbon atoms. The adsorption of T-2 toxin on these derivatives were compared with compound 3 leading to the conclusion that 3 is the best adsorbent of all investigated tetraalkylammonium-modified derivatives of 2.
Freimund
Stefan
S
Swiss Federal Institute of Technology, Laboratory of Technical Chemistry, Zurich, Switzerland. freimund@tech.chem.ethz.ch
Sauter
Martin
M
Rys
Paul
P
D000327:Adsorption; D004968:Estrogens, Non-Steroidal / Q000378:metabolism; D005936:Glucans / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D013605:T-2 Toxin / Q000378:metabolism*; D015025:Zearalenone / Q000378:metabolism*; D047071:beta-Glucans
D004968:Estrogens, Non-Steroidal; D005936:Glucans; D047071:beta-Glucans; D015025:Zearalenone; C033363:beta-1,3-glucan; D013605:T-2 Toxin