Biological efficacy of electroless-deposited silver on plasma activated polyurethane.
Silver coating of catheters has been shown to have inhibitory effects on bacterial growth and adhesion to catheter surfaces. In this study, plasma-modification was used to enhance the adhesion of an electroless silver coating on polyurethane. Both the antibacterial and antiadhesive properties of these coatings were investigated. Bacterial growth was inhibited in cultures exposed to silver-treated polyurethane compared to unmodified polyurethane. Higher growth inhibition was observed for polyurethane surfaces with lower silver coverage. Bacterial adhesion was completely inhibited on all silver-coated surfaces.
Gray
J E
JE
Department of Chemistry and Interface Science Western, University of Western Ontario, London, Ontario, Canada N6A 5B7.
Norton
P R
PR
Alnouno
R
R
Marolda
C L
CL
Valvano
M A
MA
Griffiths
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001422:Bacterial Adhesion / Q000187:drug effects* / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000494:pharmacology*; D004563:Electrochemistry / Q000379:methods; D004926:Escherichia coli / Q000166:cytology* / Q000187:drug effects* / Q000254:growth & development; D006358:Hot Temperature; D008422:Materials Testing; D011140:Polyurethanes; D016459:Prosthesis-Related Infections / Q000517:prevention & control; D012834:Silver / Q000494:pharmacology*; D013499:Surface Properties
D000900:Anti-Bacterial Agents; D020099:Coated Materials, Biocompatible; D011140:Polyurethanes; D012834:Silver