title: Ocular Hypertension Treatment Study (OHTS) commentary.
abstract: OBJECTIVE
  To summarize the major findings of the Ocular Hypertension Treatment Study (OHTS).
  
  
  RESULTS
  Ocular hypertensive subjects who received topical glaucoma medication experienced conversion to glaucoma at less than half the rate of subjects who were monitored without treatment. Risk factors for converting to glaucoma included older age, higher intraocular pressure, larger cup-disc ratio, higher pattern SD, and thinner central corneal thickness.
  
  
  CONCLUSIONS
  The OHTS clearly established that medically treating ocular hypertension is efficacious in delaying or preventing the onset of glaucoma. Further, the results may assist in providing useful guidelines for determining who with ocular hypertension should be offered medical treatment.
authors.affiliation: Creighton University School of Medicine, Omaha, Nebraska 68178, USA.
authors.forename: Brian L
authors.initials: BL
authors.lastname: Lee
authors.forename: M Roy
authors.initials: MR
authors.lastname: Wilson
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009798:Ocular Hypertension / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D014794:Visual Fields
chemical_list: D009883:Ophthalmic Solutions