title: [Syndrome of systemic inflammatory response in children with septic pyogenic complications of rhinosinusitis].
abstract: Clinical features and diagnostic and prognostic values of systemic inflammatory response syndrome (SIRS) were studied in 158 children with rhino-sinusogenic orbital and intracranial complications. Patients, whose condition was more severe, showed more SIRS markers and more often needed surgical removal of the primary infectious process in paranasal sinuses (31%). Increase of the SIRS symptoms led to an increase of organic dysfunction from 3.3% to 53.3%. The main targets for shock are the brain and meninges, with the lungs being often the second target and the hemostasis system being also often involved. Complicated rhinosinusitis should be regarded as septic if in addition to the primary infectious process the child has two or more SIRS symptoms and signs of organic dysfunctions. This approach to the diagnosis and treatment of sepsis results in recovery of 98.5 of children with this condition.
authors.forename: A N
authors.initials: AN
authors.lastname: Zinkin
authors.forename: M M
authors.initials: MM
authors.lastname: Sergeev
authors.forename: A A
authors.initials: AA
authors.lastname: Gornostaev
mesh_terms: D000293:Adolescent; D002494:Central Nervous System Infections / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality; D009916:Orbital Diseases / Q000209:etiology; D011379:Prognosis; D012220:Rhinitis / Q000150:complications*; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000175:diagnosis / Q000209:etiology; D012852:Sinusitis / Q000150:complications*; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000209:etiology
vernacular_title: Sindrom sistemnogo vospalitel'nogo otveta pri gnoĭno-septicheskikh oslozhneniiakh rinosinusitov u deteĭ.