title: N-ras mutation in a canine lymphoma: short communication.
abstract: Lymphomas of dogs were investigated by molecular genetic methods. Regions of exon 1 and 2 of the N-ras gene, which harbours the mutation hot spots (codons 12, 13 and 61) were screened. A GGT [symbol: see text] GAT (glycine [symbol: see text] aspartic acid) mutation in codon 13 was present in a multicentric-type lymphoma of a 1-year-old male dog.
authors.affiliation: Institute for Animal Breeding and Genetics, Veterinary University, Veterinärplatz 1, A-1210 Vienna, Austria. Burkhard.Mayr@vu-wien.ac.at
authors.forename: B
authors.initials: B
authors.lastname: Mayr
authors.forename: M
authors.initials: M
authors.lastname: Holzheu
authors.forename: G
authors.initials: G
authors.lastname: Schaffner
authors.forename: M
authors.initials: M
authors.lastname: Reifinger
mesh_terms: D000818:Animals; D017931:DNA Primers; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D011905:Genes, ras / Q000235:genetics*; D008223:Lymphoma / Q000235:genetics / Q000662:veterinary*; D008297:Male; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D017931:DNA Primers