title: Voiding urgency and detrusor contractility in women with overactive bladders.
abstract: OBJECTIVE
  To check whether the contractility of overactive bladders would be affected by voiding urgency.
  
  
  METHODS
  We urodynamically studied 100 women: 20 normal controls (group 1), 60 patients with idiopathic detrusor overactivity (DO), and 20 with neurogenic DO from intracerebral lesions. The idiopathic DO groups 2A (n = 20), 2B (n = 20), and 3 (n = 20) had moderate, severe, and no voiding urgency, respectively. The neurogenic DO group 4 had severe urgency. The delay time of urgent void at cystometry (2 minutes or more or, respectively, less than 2 minutes) defined moderate or severe urgency. Detrusor contractility was defined by the maximum bladder external voiding power (WF(max)).
  
  
  RESULTS
  WF(max) was higher in the idiopathic DO patients than in the controls, had the highest values in group 2B, and did not differ significantly between groups 1-4 and 2A-3.
  
  
  CONCLUSIONS
  We inferred from our data that idiopathic DO suggests a facilitation of voiding contractions and that such facilitation might be centrally amplified by severe urgency. This amplifying effect would probably be impaired in cases of neurogenic DO from intracerebral lesions.
authors.affiliation: Divisione di Urologia, Policlinico S. Matteo, IRCCS, Pavia, Italy. c.cucchi@libero.it
authors.forename: A
authors.initials: A
authors.lastname: Cucchi
authors.forename: S
authors.initials: S
authors.lastname: Siracusano
authors.forename: C
authors.initials: C
authors.lastname: Guarnaschelli
authors.forename: B
authors.initials: B
authors.lastname: Rovereto
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009119:Muscle Contraction; D009122:Muscle Hypertonia / Q000503:physiopathology*; D001743:Urinary Bladder / Q000503:physiopathology; D014555:Urination Disorders / Q000503:physiopathology*; D014563:Urodynamics