title: [The 1(2)-dehydrogenation of steroid substrates by Nocardioides simplex VKM Ac-2033D].
abstract: The bacterium formerly known as Arthrobacter globiformis 193 has high 1(2)-dehydrogenase activity toward pharmaceutically important steroids, 9(11)-dehydrocortexolone in particular. The complex analysis of the morphostructural, physiological, biochemical, and phylogenetic properties of this bacterium allowed us to reclassify it into Nocardioides simplex (N. simplex VKM Ac-2033D).
authors.affiliation: Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Fokina
authors.forename: G V
authors.initials: GV
authors.lastname: Sukhodol'skaia
authors.forename: S A
authors.initials: SA
authors.lastname: Gulevskaia
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Gavrish
authors.forename: L I
authors.initials: LI
authors.lastname: Evtushenko
authors.forename: M V
authors.initials: MV
authors.lastname: Donova
mesh_terms: D001173:Arthrobacter / Q000145:classification / Q000378:metabolism*; D003350:Cortodoxone / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D009618:Nocardiaceae / Q000145:classification / Q000378:metabolism*; D010802:Phylogeny; D012329:RNA, Bacterial / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D013256:Steroids / Q000737:chemistry / Q000378:metabolism*
chemical_list: D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D013256:Steroids; D006913:Hydroxysteroid Dehydrogenases; D003350:Cortodoxone
vernacular_title: 1(2)-degidrirovanie steroidnykh substratov shtammom Nocardioides simplex BKM Ac-2033D.