title: Splenic spontaneous rupture (SSR) and hemoperitoneum associated with low molecular weight heparin: a case report.
abstract: We describe the first case of spontaneous splenic rupture associated with tinzaparin in a cancer patient. This low-molecular-weight heparin was administrated for deep venous thrombosis and pulmonary embolism. No underlying splenic pathology predisposing to this condition was found.
authors.affiliation: Service de Soins Intensifs (ASTI), Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Rue Heger-Bordet 1, 1000 Brussels, Belgium.
authors.forename: Fabio Silvio
authors.initials: FS
authors.lastname: Taccone
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Starc
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Sculier
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006465:Hemoperitoneum / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology; D011655:Pulmonary Embolism / Q000188:drug therapy; D011859:Radiography; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013997:Time Factors; D000078222:Tinzaparin; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D000078222:Tinzaparin