NMR-microscopy with TrueFISP at 11.75T.
The purpose of this paper is to demonstrate that a fully balanced gradient echo technique (TrueFISP) can be used for microscopic experiments at high static magnetic field strengths. TrueFISP experiments were successfully performed on homogeneous and inhomogeneous objects at 11.75T. High-resolution TrueFISP images were obtained from phantoms, plants, formalin-fixed samples, and from an isolated beating rat heart with an in-plane resolution of 78 micro m and a slice thickness of 500 micro m. The signal-to-noise ratio (SNR) gain of TrueFISP compared to conventional gradient echo or spin echo sequences will allow faster acquisition times or an improvement in spatial resolution for microscopic experiments.
Köhler
Sascha
S
Physikalisches Institut, EP5, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany. sakoehler@physik.uni-wuerzburg.de
Hiller
Karl-Heinz
KH
Griswold
Mark
M
Bauer
Wolfgang R
WR
Haase
Axel
A
Jakob
Peter M
PM
D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006321:Heart / Q000502:physiology*; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D003287:Contrast Media; D019786:Gadolinium DTPA