title: [Role of Shigella flexneri type-specific antigen in bacterial resistance to oxidative stressor].
abstract: Lac+ type- S. flexneri 1298 1a and S. flexneri 1338 1b hybrids has been obtained in the crosses of Shigella strains with Escherichia coli K-12 Hfr C. The detection of in vitro survive of the bacteria of genetically linked pair strains, differing in type specific antigen synthesis is presented. The more sensitive of lac+ type- hybrids to the treatment by hydrogen peroxide of concentration 205 mM in comparison with the parent S. flexneri strains possesses the type specific antigen synthesis was shown.
authors.affiliation: Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
authors.forename: I L
authors.initials: IL
authors.lastname: Mal'shakova
mesh_terms: D000942:Antigens, Bacterial / Q000145:classification / Q000235:genetics / Q000276:immunology*; D003433:Crosses, Genetic; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000145:classification / Q000235:genetics / Q000276:immunology; D008040:Genetic Linkage; D006824:Hybridization, Genetic; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007763:Lac Operon / Q000235:genetics; D008070:Lipopolysaccharides / Q000276:immunology; D018384:Oxidative Stress / Q000187:drug effects*; D011995:Recombination, Genetic; D012703:Serotyping; D012763:Shigella flexneri / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D013045:Species Specificity
chemical_list: D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D006861:Hydrogen Peroxide
vernacular_title: Rol' tipovogo antigena Shigella flexneri v ustoĭchivosti bakteriĭ k oksidativnomu stressoru.