title: Effects of rare earth elements on the growth of Cistanche deserticola cells and the production of phenylethanoid glycosides.
abstract: The rare earth elements Nd, La, Ce at proper concentrations had positive effects on the cell growth of Cistanche deserticola and production of phenylethanoid glycosides (PeG). A mixture of rare earth elements (MRE, La(2)O(3):CeO(2):Pr(6)O(11):Sm(2)O(3)=255:175:3:1, mol/mol) showed the most remarkable effects. After 30 day's culture, 0.02 mmoll(-1) MRE gave the highest content (20.8%) and production (1.6 gl(-1)) of PeG, which were 104 and 167% higher than those obtained in control (without rare earth elements).
authors.affiliation: State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, China. joyouyang@yahoo.com
authors.forename: Jie
authors.initials: J
authors.lastname: Ouyang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Wang
authors.forename: Bing
authors.initials: B
authors.lastname: Zhao
authors.forename: Xiaofan
authors.initials: X
authors.lastname: Yuan
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Wang
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D031671:Cistanche / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development*; D004305:Dose-Response Relationship, Drug; D006027:Glycosides / Q000096:biosynthesis*; D008674:Metals, Rare Earth / Q000494:pharmacology*
chemical_list: D006027:Glycosides; D008674:Metals, Rare Earth