[Epidemiological effect of hepatitis B immunization among newborn babies in Beijing].
OBJECTIVE
To evaluate the epidemiological effect of hepatitis B immunization among newborn babies in Beijing.


METHODS
A multistage sampling method was used for the collection of immunization cards, field epidemiological survey on hepatitis B virus (HBV) immunization of children, analysis of infectious disease reports. HBsAg, anti-HBs and anti-HBc levels were detected by solid phase radioimmunoassays (SPRIA).


RESULTS
The incidence of hepatitis B in children of 0 to 14 years at the beginning of HBV immunization was 18.59 to 20.52/100,000, and declined to 0.39 to 2.38/100,000 in 2000 (chi2 = 58.26, P < 0.01). The HBsAg carrying rate of the children decreased from 2.82% to 0.60%, about 80.00% after vaccination (chi2 = 10.75, P < 0.01).


CONCLUSIONS
Hepatitis B vaccination of newborn babies is an effective measure for prevention and control of hepatitis B virus infection.
Gong
Xiao-hong
XH
Institute of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Liu
Li-rong
LR
Jia
Lei
L
Li
Yang-hua
YH
Xing
Yu-lan
YL
Wang
Quan-yi
QY
D002681:China / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000517:prevention & control*; D006514:Hepatitis B Surface Antigens / Q000097:blood / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D016036:Seroepidemiologic Studies; D014611:Vaccination
D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines