Cystoid macular edema associated with latanoprost therapy in a pseudophakic vitrectomized patient after removal of silicone oil endotamponade.
OBJECTIVE
To describe the occurrence of cystoid macular edema in a pseudophakic vitrectomized patient following use of latanoprost (0.005%).


METHODS
A 58-year-old patient underwent routine cataract surgery with posterior chamber lens implantation complicated by rhegmatogenous retinal detachment three months later. A pars plana vitrectomy was performed with silicone oil endotamponade which was removed six months later. Five months after oil removal, the patient presented with secondary open-angle glaucoma treated with latanoprost 0.005% eye drops once daily.


RESULTS
Two weeks after initiation of latanoprost treatment, visual acuity dropped from 0.8 to 0.3 due to cystoid macular edema confirmed by fluorescein angiography. After discontinuing latanoprost therapy and with topical corticosteroid treatment, cystoid macular edema slowly resolved, and within 6 months, visual acuity improved to 0.8.


CONCLUSIONS
Despite its marked ocular hypotensive effect, latanoprost should be carefully used in patients after uncomplicated cataract surgery if the vitreous body was removed by pars piana vitrectomy.
Jäger
M
M
Department of Ophthalmology, Eye Hospital, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany.
Jonas
J B
JB
D000959:Antihypertensive Agents / Q000009:adverse effects*; D004322:Drainage; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D000077338:Latanoprost; D019654:Lens Implantation, Intraocular; D008269:Macular Edema / Q000139:chemically induced*; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D019591:Pseudophakia / Q000150:complications*; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery; D012827:Silicone Oils; D014821:Vitrectomy
D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D012827:Silicone Oils; D000077338:Latanoprost