Gallium-67 demonstration of extensive soft-tissue involvement of multiple myeloma.
A 46-year-old woman with multiple myeloma presented with neurological symptoms in the right upper extremity. After MR imaging of the cervical spine failed to show the cause of her symptoms, Ga-67 scintigraphy demonstrated increased uptake in multiple areas including the right supraclavicular region and bilateral lower extremities. Histology of the specimen obtained from the left thigh proved soft-tissue involvement of myeloma, and extensive extramedullary involvement was diagnosed. Radiotherapy to the right supraclavicular mass relieved her symptoms. Although Ga-67 scintigraphy is generally considered of limited value in multiple myeloma, this modality contributed to the development of an appropriate strategy in this patient with extensive extramedullary involvement.
Hosono
Makoto
M
Department of Radiology, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan. makohoso@saitama-med.ac.jp
Machida
Kikuo
K
Inoue
Yusuke
Y
Honda
Norinari
N
Takahashi
Takeo
T
Kashimada
Akio
A
Ohtawa
Nobuyuki
N
Ohno
Hitoshi
H
Yamano
Takafumi
T
D002951:Citrates; D005260:Female; D005708:Gallium; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D013848:Thigh / Q000000981:diagnostic imaging; D034941:Upper Extremity / Q000000981:diagnostic imaging; D014915:Whole-Body Counting
D002951:Citrates; D019275:Radiopharmaceuticals; D005708:Gallium; C103850:gallium citrate