Opioid receptor coupling to GIRK channels. In vitro studies using a Xenopus oocyte expression system and in vivo studies on weaver mutant mice.
Ikeda
Kazutaka
K
Department of Molecular Psychiatry, Tokyo Institute of Psychiatry, Laboratory for Neurobiology of Emotion, RIKEN Brain Science Institute, Japan.
Yoshii
Mitsunobu
M
Sora
Ichiro
I
Kobayashi
Toru
T
D000701:Analgesics, Opioid / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology; D018076:DNA, Complementary / Q000235:genetics; D004259:DNA-Directed DNA Polymerase / Q000235:genetics; D005260:Female; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D015870:Gene Expression; D005822:Genetic Vectors; D005838:Genotype; D066298:In Vitro Techniques; D051379:Mice; D008818:Mice, Neurologic Mutants; D008954:Models, Biological; D020125:Mutation, Missense; D009865:Oocytes; D018408:Patch-Clamp Techniques; D010957:Plasmids; D017354:Point Mutation; D015221:Potassium Channels / Q000235:genetics / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011957:Receptors, Opioid / Q000378:metabolism*; D012680:Sensitivity and Specificity; D014981:Xenopus
D000701:Analgesics, Opioid; D018076:DNA, Complementary; D015221:Potassium Channels; D012333:RNA, Messenger; D011957:Receptors, Opioid; D004259:DNA-Directed DNA Polymerase; D019204:GTP-Binding Proteins