Ocular Hypertension Treatment Study (OHTS) commentary.
OBJECTIVE
To summarize the major findings of the Ocular Hypertension Treatment Study (OHTS).


RESULTS
Ocular hypertensive subjects who received topical glaucoma medication experienced conversion to glaucoma at less than half the rate of subjects who were monitored without treatment. Risk factors for converting to glaucoma included older age, higher intraocular pressure, larger cup-disc ratio, higher pattern SD, and thinner central corneal thickness.


CONCLUSIONS
The OHTS clearly established that medically treating ocular hypertension is efficacious in delaying or preventing the onset of glaucoma. Further, the results may assist in providing useful guidelines for determining who with ocular hypertension should be offered medical treatment.
Lee
Brian L
BL
Creighton University School of Medicine, Omaha, Nebraska 68178, USA.
Wilson
M Roy
MR
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009798:Ocular Hypertension / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D014794:Visual Fields
D009883:Ophthalmic Solutions