Testosterone urinary excretion rate increases during hypergravity in male monkeys.
Real and simulated microgravity impairs T secretion both in animals and in the human. To verify whether hypergravity might enhance T secretion as a consequence of an opposite mechanical effect, 6 male monkeys were centrifuged at 2 G for 3 weeks after a 1 G stabilization period lasting 3 weeks and then taken back to 1 G for 1 week and urine were collected daily for T excretion measurement. Significantly higher level were observed during the initial 2 G phase as compared to pre- and post centrifugation periods and the trend was the same during the remaining 2 G period. This may reflect changes in testicular perfusion rather than endocrine adaptation per se.
Strollo
F
F
I.N.R.C.A. Endocrine Unit, Rome, Italy.
Barger
L
L
Fuller
C
C
D000818:Animals; D001522:Behavior, Animal; D002498:Centrifugation; D018471:Hypergravity; D008253:Macaca mulatta; D008297:Male; D015203:Reproducibility of Results; D012930:Social Dominance; D013739:Testosterone / Q000378:metabolism* / Q000652:urine*
D013739:Testosterone