title: [Significance of maternal and paternal age in assisted reproduction programs].
abstract: BACKGROUND
  Many infertile couples try to become parents spontaneously, neglecting the possibility to conceive artificially, so they seek medical help in their late reproductive age.
  Major aspects of maternal age in regard to assisted reproduction consider oocytes, ovaries and endometrium. Also, some habits and maternal diseases associated with aging may have an impact on fertility (smoking, atherosclerosis, previous gynecological operations etc.). Even though estimating the ovarian reserve is the most objective test in assessing female fertility, it has a limited predictive value in younger women. A short protocol of ovulation induction showed best results in women with poor ovarian reserve, but recent studies recommend low-dose gonadotropin-releasing hormone agonists in these cases.
  With aging, sperm parameters become worse, which points to the neglected role of the father in assisted reproduction.
  
  
  CONCLUSIONS
  Thus, parental age plays an important role in assisted reproductive programs.
authors.affiliation: Klinika za ginekologiju i akuserstvo, 21000 Novi Sad, Branimira Cosića 37.
authors.forename: Dunja
authors.initials: D
authors.lastname: Tabs
authors.forename: Nebojsa
authors.initials: N
authors.lastname: Radunović
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008423:Maternal Age; D010331:Paternal Age; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted
vernacular_title: Znacaj godina starosti majke i oca u programu asistirane reprodukcije.