title: Zygomycosis: A report of eleven cases and a review of the Brazilian literature.
abstract: Eleven cases of zygomycosis (mucormycosis) observed throughout an eighteen year period (1982-2000) have been reviewed. The most important demographic and clinical data of seven patients were tabulated. The remaining four are related as illustrative cases. Seven patients presented with the pulmonary form of the disease; two patients presented with the pulmonary manifestation associated with sinusitis; and two patients presented with the rhinocerebral form. Predisposing conditions, in decreasing order of frequency, were diabetes mellitus (6), renal transplantation (2), associated with pancreas-kidney transplantation and diabetes (1), bone marrow aplasia (1), and chronic obstructive lung disease treated with corticosteroids (1). The diagnoses were based on the detection of characteristic zygomycetous hyphae in tissue. The causative organim was isolated and identified in only four cases; three were due to Rhizopus arrhizus, and one to Absidia corymbifera. In addition the Brazilian literature on zygomycosis is reviewed.
authors.affiliation: Laboratório de Microbiologia Clínica, IPD - Santa Casa, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Annes Dias, 285, Porto Alegre 90020-090, RS, Brasil. severo@santacasa.tche.br
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Severo
authors.forename: Flávio De Mattos
authors.initials: FD
authors.lastname: Oliveira
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Dreher
authors.forename: Paulo Zimmermann
authors.initials: PZ
authors.lastname: Teixeira
authors.forename: Nelson Da Silva
authors.initials: ND
authors.lastname: Porto
authors.forename: Alberto Thomas
authors.initials: AT
authors.lastname: Londero