title: MR-guided catheter navigation of the intracranial subarachnoid space.
abstract: Percutaneous intraspinal navigation (PIN) is a new minimally invasive approach to the CNS. The authors studied the utility of MR-guided intracranial navigation following access to the subarachnoid compartment via PIN. The passive tracking technique was employed to visualize devices during intracranial navigation. Under steady-state free precession (SSFP) MR-guidance a microcatheter-microguidewire was successfully navigated to multiple brain foci in two cadavers. SSFP MR fluoroscopy possesses adequate contrast and temporal resolution to allow MR-guided intracranial navigation.
authors.affiliation: Department of Radiology, Division of Neuroradiology, the University of Texas Southwestern Medical Center at Dallas, USA.
authors.forename: George
authors.initials: G
authors.lastname: Rappard
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Metzger
authors.forename: James L
authors.initials: JL
authors.lastname: Fleckenstein
authors.forename: Evelyn E
authors.initials: EE
authors.lastname: Babcock
authors.forename: Paul T
authors.initials: PT
authors.lastname: Weatherall
authors.forename: Robert E
authors.initials: RE
authors.lastname: Replogle
authors.forename: G Lee
authors.initials: GL
authors.lastname: Pride
authors.forename: Susan L
authors.initials: SL
authors.lastname: Miller
authors.forename: Christina E
authors.initials: CE
authors.lastname: Adams
authors.forename: Phillip D
authors.initials: PD
authors.lastname: Purdy
mesh_terms: D001921:Brain / Q000473:pathology*; D002408:Catheters, Indwelling; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004867:Equipment Design; D005240:Feasibility Studies; D005471:Fluoroscopy; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D038361:Neuronavigation / Q000295:instrumentation*; D012680:Sensitivity and Specificity; D013129:Spinal Puncture / Q000295:instrumentation*; D013346:Subarachnoid Space / Q000473:pathology*