title: Altered gravity modulates prostaglandin H synthase in human K562 cells.
abstract: In this study, we extended our previous observations on the effects of altered gravity on the "lipoxygenase pathway", by ascertain the possible role of the force of gravity in modulating the activity and expression of PHS in human erythro-leukemia K562 cells.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences and Biomedical Space Center, University of Rome, "Tor Vergata", Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Maccarrone
authors.forename: M
authors.initials: M
authors.lastname: Bari
authors.forename: T
authors.initials: T
authors.lastname: Lorenzon
authors.forename: A
authors.initials: A
authors.lastname: Finazzi-Agrò
mesh_terms: D001094:Arachidonate 5-Lipoxygenase / Q000378:metabolism; D002498:Centrifugation; D005786:Gene Expression Regulation; D018470:Gravity, Altered; D006801:Humans; D018471:Hypergravity; D020014:K562 Cells / Q000201:enzymology*; D008213:Lymphocyte Activation / Q000502:physiology; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D012399:Rotation; D018474:Weightlessness Simulation
chemical_list: D001094:Arachidonate 5-Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases