title: Sideroblastic anaemia with reactive thrombocytosis versus myelodysplastic/myeloproliferative disease.
abstract: The reported incidence of thrombocytosis among cases of refractory anaemia with ring sideroblasts (RARS) may be as high as 15%. We report four additional cases of this association, which appear to be hematologically heterogeneous. One patient clearly represents a case of RARS with reactive thrombocytosis. Two cases have features suggestive of the coincidental occurrence of essential thrombocythemia and RARS. The fourth case could be best classified as a subtype of myelodysplastic/myeloproliferative disease unclassifiable (MDS/MPD U). Only new biological or molecular markers will allow better differentiation between these disorders.
authors.forename: I
authors.initials: I
authors.lastname: Pérez Sánchez
authors.forename: A
authors.initials: A
authors.lastname: Pérez Corrala
authors.forename: J
authors.initials: J
authors.lastname: Menarguez Palanca
authors.forename: M
authors.initials: M
authors.lastname: Mayayo Crespo
authors.forename: A
authors.initials: A
authors.lastname: Escudero Soto
authors.forename: T
authors.initials: T
authors.lastname: Pintado Cros
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000756:Anemia, Sideroblastic / Q000150:complications / Q000175:diagnosis*; D001799:Blood Sedimentation; D001853:Bone Marrow / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003937:Diagnosis, Differential; D004900:Erythroblasts / Q000473:pathology; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007621:Karyotyping; D008297:Male; D009190:Myelodysplastic Syndromes / Q000145:classification / Q000175:diagnosis*; D009196:Myeloproliferative Disorders / Q000145:classification / Q000175:diagnosis*; D011014:Pneumonia / Q000150:complications; D013922:Thrombocytosis / Q000150:complications / Q000175:diagnosis*