title: Residential Environment, Diet and Risk of Stomach Cancer: a Case-control Study in Linzhou, China.
abstract: A case-control study was conducted to investigate risk factors for stomach cancer in a rural population in China. Linzhou Cancer Registry was used to identify cases of stomach cancer, aged between 30 and 75 years, diagnosed between January 1998 and April 1999. Three neighbourhood controls were selected for each case, matched according to age, sex and village of residence. A total of 210 cases and 630 controls were interviewed. Conditional logistic regression was used to estimate odds ratios (OR) for factors associated with the risk of cancer. Among characteristics of the residential environment, significantly increased risk was found for: frequent irritation on eyes or throat by soot (OR 5.54, 95% CI 1.42-21.65, p for trend <0.01). This effect was particularly strong in women (OR 19.5, 95% CI 1.28-297.09, p for trend =0.01). Dietary factors that were significantly associated with an increased risk were food grains other than rice, wheat and maize (OR 2.93, 95% 1.16-7.38), pickled or salted vegetables (OR 3.99, 95% CI 1.63-9.75) and preference for a high salt diet (OR 2.58, 95% CI 1.56-4.26). The consumption of vegetables showed a protective effect with an odds ratio of 0.27 (95% CI 0.11-0.61). It follows that a developing economy and improvement in living standards, with associated increased intake of fruit and vegetables and reduced consumption of salt, can contribute to a reduction in the incidence of stomach cancer in the Linzhou population.
authors.affiliation: Thames Cancer Registry, London SE1 3QD, UK. Xbsun21@sina.com
authors.forename: Sun
authors.initials: S
authors.lastname: Xibin
authors.forename: Henrik
authors.initials: H
authors.lastname: Moller
authors.forename: Helen S
authors.initials: HS
authors.lastname: Evans
authors.forename: Dai
authors.initials: D
authors.lastname: Dixing
authors.forename: Duan
authors.initials: D
authors.lastname: Wenjie
authors.forename: Lu
authors.initials: L
authors.lastname: Jianbang