title: Mechanical properties and in vitro degradation of bioabsorbable self-expanding braided stents.
abstract: The aim of this study was to characterize the mechanical and self-expansion properties of braided bioabsorbable stents. In total four different stents were manufactured from PLLA fibres using a braiding technique. The changes in radial pressure stiffness and diameter recovery of the stents were determined initially, and after insertion and release from a delivery device. The braided stents were compared to three commercially available metallic braided stents. The changes in physical and mechanical properties of the PLLA fibres and stents during in vitro degradation were investigated. After release from the delivery device, the PLLA stents did not fully recover to their original diameter. The radial pressure stiffness of the bioabsorbable stents was similar to that of the metallic stents. The in vitro degradation study showed that the stents would keep at least half of their initial radial pressure stiffness for more than 22 weeks.
authors.affiliation: Institute of Biomaterials, Tampere University of Technology, PO Box 589, FIN-33101 Tampere, Finland.
authors.forename: Juha-Pekka
authors.initials: JP
authors.lastname: Nuutinen
authors.forename: Claude
authors.initials: C
authors.lastname: Clerc
authors.forename: Raija
authors.initials: R
authors.lastname: Reinikainen
authors.forename: Pertti
authors.initials: P
authors.lastname: Törmälä
mesh_terms: D001673:Biodegradation, Environmental; D004548:Elasticity; D004867:Equipment Design; D011091:Polyesters / Q000737:chemistry* / Q000493:pharmacokinetics; D015607:Stents; D014783:Viscosity
chemical_list: D011091:Polyesters; C033616:poly(lactide)