[Regeneration of the cornea].
The cornea is a transparent, colorless tissue that functions as the optical surface of the eye. Transparency is vital for useful vision, which can be compromised by disorders to the corneal epithelium, stroma or endothelium. Transplantation of donor corneas is the standard surgical procedure for irreversible damage to the tissue. However, Japan, as well as many countries across the globe, are suffering from a shortage of donor supplies. Recent developments in bioengineering techniques have opened the way for the possible development of regenerated tissue from cultured progenitor cells. An artificial cornea with all the necessary cell components may become available in the near future.
Shimmura
Shigeto
S
Department of Ophthalmology, Tokyo Dental College.
Tsubota
Kazuo
K
D000650:Amnion / Q000637:transplantation; D001187:Artificial Organs; D002478:Cells, Cultured; D003315:Cornea / Q000502:physiology*; D003316:Corneal Diseases / Q000628:therapy; D019573:Epithelium, Corneal / Q000166:cytology; D016332:Fetal Tissue Transplantation; D006801:Humans; D012038:Regeneration; D033581:Stem Cell Transplantation; D023822:Tissue Engineering