title: Clinicopathologic correlations in 646 consecutive surgical eye specimens, 1990-2000.
abstract: All surgical eye specimens examined in our pathology laboratory between January 1, 1990, and July 31, 2000 (N = 646), were classified by surgical procedure (enucleation, evisceration, or exenteration) and pathologic diagnosis. Among 523 enucleated globes (81.0%), 252 (48.2%) contained tumors, of which 208 were intraocular malignant melanomas. Nonneoplastic causes for enucleation included glaucoma (67/523 [12.8%]), phthisis bulbi (61/523 [11.7%]), and recent trauma (59/523 [11.3%]). Sixty-seven specimens (10.4%) had been eviscerated. Fifty-six specimens (8.7%) were obtained by exenteration performed to manage malignant tumors originating in or invading the orbit. Between 1990 and 2000, the percentage of procedures performed to remove neoplasms decreased from 65% to 38%, procedures performed to treat glaucoma increased from 4% to 29%, and those to treat phthisis bulbi increased from 8% to 13%. The numbers of procedures remained relatively constant for trauma and for infectious and inflammatory diseases.
authors.affiliation: Mayo Medical School, Mayo Clinic, Rochester, MN, USA.
authors.forename: Anna S
authors.initials: AS
authors.lastname: Kitzmann
authors.forename: Amy L
authors.initials: AL
authors.lastname: Weaver
authors.forename: Christine M
authors.initials: CM
authors.lastname: Lohse
authors.forename: Helmut
authors.initials: H
authors.lastname: Buettner
authors.forename: Diva R
authors.initials: DR
authors.lastname: Salomão
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005123:Eye / Q000473:pathology*; D005128:Eye Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery; D015353:Eye Enucleation / Q000706:statistics & numerical data / Q000639:trends; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D008910:Minnesota; D013508:Ophthalmologic Surgical Procedures / Q000706:statistics & numerical data; D012189:Retrospective Studies; D017678:Sex Distribution