title: Semi-quantitative CBF and CBF ratios obtained using perfusion-weighted MR imaging.
abstract: To clarify the utility of semi-quantitative cerebral blood flow (CBF) measurements using perfusion-weighted MR imaging (PWI), a comparison of this method with quantitative CBF obtained using PET was conducted in 10 patients with chronic occlusive cerebrovascular disease and unilateral occlusion of the cerebral artery. Semi-quantitative CBF obtained using PWI and quantitative CBF obtained using PET showed no statistically significant correlation. The CBF ratios of the affected side relative to the contralateral unaffected side obtained using PWI and PET were 0.94 +/- 0.22 and 0.88 +/- 0.19, respectively. A statistically significant positive correlation was obtained between these ratios (p < 0.01). The CBF ratio, but not the semi-quantitative CBF, obtained using PWI has a potential to detect changes in the CBF.
authors.affiliation: Neurosurgery, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. fmihara@radiol.med.kyushu-u.ac.jp
authors.forename: Futoshi
authors.initials: F
authors.lastname: Mihara
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kuwabara
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshiura
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tanaka
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kaneko
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
authors.forename: Toshio
authors.initials: T
authors.lastname: Matsushima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D014055:Tomography, Emission-Computed