title: Ascites and elevated androgen level in a pregnant patient with an ovarian sclerosing stromal tumor.
abstract: We report the case of a 31-year-old woman with an androgen-producing sclerosing stromal tumor found during the eighth week of gestation in association with ascites and elevated serum androgen and cancer antigen (CA)-125 levels. The combined features of ascites, elevated serum androgen and elevated CA-125 in association with this rare type of ovarian tumor is unusual. Surgical removal of the tumor resulted in relief of symptoms, resolution of ascites, and decreases in serum androgen and CA-125 levels. The pregnancy was uneventful.
authors.affiliation: Departments of Obstetrics & Gynecology, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan.
authors.forename: Soon-Cen
authors.initials: SC
authors.lastname: Huang
authors.forename: Hsiang-Chun
authors.initials: HC
authors.lastname: Chen
authors.forename: Kong-Chao
authors.initials: KC
authors.lastname: Chang
authors.forename: Cheng-Yang
authors.initials: CY
authors.lastname: Chou
mesh_terms: D000328:Adult; D000728:Androgens / Q000096:biosynthesis*; D001201:Ascites / Q000209:etiology; D018394:CA-125 Antigen / Q000097:blood; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery; D018312:Sex Cord-Gonadal Stromal Tumors / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery
chemical_list: D000728:Androgens; D018394:CA-125 Antigen