[Serum and bronchoalveolar lavage fluid neopterin levels in patients with bronchial asthma].
Neopterin is an activation marker of macrophages. These cells become activated in bronchial asthma. The aim of the study was to measure serum and BALF neopterin levels in patients with bronchial asthma. The study included 15 patients with moderate, stable bronchial asthma. Serum neopterin levels were normal, while those in BALF were increased. The results of the study seem to indicate that in patients with moderate stable bronchial asthma alveolar macrophages are activated, as shown by increased levels of neopterin in BALF.
Passowicz-Muszyńska
Ewa
E
Katedra i Klinika Chorób Płuc, Akademii Medycznej we Wrocławiu.
Krasnowska
Maryla
M
Jankowska
Renata
R
Piesiak
Paweł
P
D000328:Adult; D001249:Asthma / Q000201:enzymology*; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D005260:Female; D005540:Forced Expiratory Flow Rates; D005541:Forced Expiratory Volume; D006801:Humans; D008262:Macrophage Activation; D008297:Male; D008875:Middle Aged; D019798:Neopterin / Q000032:analysis* / Q000097:blood*; D013997:Time Factors
D019798:Neopterin
Stezenia neopteryny w surowicy i popłuczynach oskrzelowo-pecherzykowych u chorych na astme oskrzelowa (doniesienie wstepne).