[Pathology of implants].
Progress in the surgery of implants and biomaterials can be accomplished by: 1. Painstakingly analysing and registering of defaulting implants after explantation within a "National Registry of Implant Pathology". 2. Development of a DNA-microarray named "Implantat/Chronic Wound" in order to discover the differential transcriptional activities of cells brought into contact with different foreign surfaces. 3. Predictive cell-engineering combined with custom-made implant surfaces with the aim of optimal patient care.
Mittermayer
C
C
Institut für Pathologie, Universitätsklinikum, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen.
Eblenkamp
M
M
Richter
H A
HA
Zwadlo-Klarwasser
G
G
Bhardwaj
R S
RS
Klosterhalfen
B
B
D002478:Cells, Cultured / Q000473:pathology; D019544:Equipment Failure Analysis / Q000379:methods*; D005549:Foreign-Body Reaction / Q000473:pathology*; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D011183:Postoperative Complications / Q000473:pathology*; D011474:Prosthesis Design; D012042:Registries
Pathologie der Implantate.