Postoperative endocrine management of pituitary tumors.
Pituitary tumors are common and are often associated with endocrine abnormalities. Furthermore, pituitary surgery itself may result in additional hormonal changes, including impairment of anterior pituitary hormone secretion and, more commonly, abnormalities of ADH regulation. Endocrine management of patients with pituitary or other sellar lesions involves acute hospital-based and longer term office-based evaluation and treatment. In the immediate postoperative period, careful attention must be directed toward sodium and water balance as well as toward recognition of changes in endocrine function. Postoperative measurement of serum hormone levels also helps to determine if resection of a hypersecreting tumor has been successful. To minimize postoperative morbidity, perioperative endocrine assessment and management of patients undergoing pituitary surgery should consist of a team approach, involving both the neurosurgeon and the endocrinologist.
Singer
Peter A
PA
Division of Endocrinology and Metabolism, Keck School of Medicine, University of Southern California, 1355 San Pablo Street, Room 118, Los Angeles, CA 90033, USA. psinger@hsc.usc.edu
Sevilla
Linda J
LJ
D003919:Diabetes Insipidus / Q000517:prevention & control; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000517:prevention & control; D010911:Pituitary Neoplasms / Q000378:metabolism / Q000601:surgery*; D011182:Postoperative Care