Significant delay of birth in advanced preterm labour at 23 gestational weeks with an oxytocin antagonist.
A 27-year-old primigravid woman with advanced preterm labour at 23 weeks and 5 days gestation received tocolytic therapy with a continuous infusion of the oxytocin antagonist, atosiban, during 154 h. The delivery was postponed for 12 days. The baby was discharged after 3 months of neonatal care and at 6 months of age is healthy. The prolonged treatment was not associated with maternal or fetal side effects.
Herbst
Andreas
A
Department of Obstetrics and Gynecology, University Hospital, University of Lund, Lund 221 85, Sweden.
Wide-Swensson
Dag
D
Ingemarsson
Ingemar
I
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002097:C-Reactive Protein / Q000032:analysis; D002444:Cefuroxime / Q000008:administration & dosage; D002584:Cervix Uteri / Q000382:microbiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D010121:Oxytocin / Q000037:antagonists & inhibitors*; D011247:Pregnancy; D013292:Streptococcus agalactiae; D013726:Terbutaline / Q000008:administration & dosage / Q000009:adverse effects; D014668:Vasotocin / Q000008:administration & dosage* / Q000031:analogs & derivatives*
D000900:Anti-Bacterial Agents; C047046:atosiban; D008795:Metronidazole; D010121:Oxytocin; D002097:C-Reactive Protein; D013726:Terbutaline; D002444:Cefuroxime; D014668:Vasotocin