title: [Association of systemic diseases and myelodysplastic syndromes. A retrospective study of 14 cases].
abstract: BACKGROUND
  The association of a systemic disease (SD) and a myelodysplastic syndrome (MDS) may not be a coincidence. We report 14 cases.
  
  
  METHODS
  A retrospective study was conducted in patients presenting with an MDS, hospitalised between 1989 and 1999, in the search for a concomitant systemic disease.
  
  
  RESULTS
  Ninety-seven patients, 61 men and 36 women, with a mean age of 74 +/- 11 years suffered from an MDS and 14 of them a concomitant SD: one nodular periateritis, 2 systemic vascularitis, 2 cutaneous vascularitis, 2 atrophic polychondritis, 4 Gougerot-Sjogrën syndrome, 2 systemic lupus and one cutaneous lupus. The systemic disease did not appear to influence survival.
  
  
  CONCLUSIONS
  It is possible that the association is not a coincidence and therefore an MDS should be searched for when confronted with an SD, so that treatment may be adapted appropriately.
authors.affiliation: Service de médecine interne et de maladies infectieuses et tropicales CHU La Milétrie Poitiers.
authors.forename: F
authors.initials: F
authors.lastname: Roy-Peaud
authors.forename: M
authors.initials: M
authors.lastname: Paccalin
authors.forename: G
authors.initials: G
authors.lastname: Le Moal
authors.forename: C
authors.initials: C
authors.lastname: Landron
authors.forename: L
authors.initials: L
authors.lastname: Juhel
authors.forename: P
authors.initials: P
authors.lastname: Roblot
authors.forename: B
authors.initials: B
authors.lastname: Becq-Giraudon
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001379:Azathioprine / Q000627:therapeutic use; D001803:Blood Transfusion; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008178:Lupus Erythematosus, Cutaneous / Q000150:complications* / Q000401:mortality; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000401:mortality / Q000628:therapy; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000401:mortality; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000401:mortality; D012189:Retrospective Studies; D012859:Sjogren's Syndrome / Q000150:complications* / Q000401:mortality; D013997:Time Factors; D014657:Vasculitis / Q000150:complications* / Q000401:mortality
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D001379:Azathioprine
vernacular_title: Association maladies systémiques et syndromes myélodysplasiques. Etude rétrospective portant sur 14 observations.