Paraprotein and beta2-microglobulin analyses in multiple myeloma--do we need to monitor both?
The relationship between serum paraprotein and beta2-microglobulin (B2m) levels was studied in serial samples from 41 patients with myeloma. A positive correlation coefficient was found in 70.7% of myeloma patients indicating that no extra information was gained from measuring both analytes routinely. As a result, the workload for B2m fell without any diminution in clinical service.
Sinclair
David
D
Department of Chemical Pathology, Queen Alexandra Hospital, Portsmouth, UK. david.sinclair@porthosp.nhs.uk
Cranfield
Tanya
T
Ganczakowski
Mary
M
D006801:Humans; D007132:Immunoglobulin Isotypes / Q000097:blood; D009101:Multiple Myeloma / Q000175:diagnosis*; D010266:Paraproteins / Q000032:analysis*; D001613:beta 2-Microglobulin / Q000097:blood*
D007132:Immunoglobulin Isotypes; D010266:Paraproteins; D001613:beta 2-Microglobulin