title: Why Intervention Studies are Needed for Development of Cancer Preventive Foodstuffs.
abstract: In order to put nutrition advice on cancer preventive agents on an evidence basis, appropriate intervention studies in high risk human populations are necessary. Although epidemiological observations are clearly very important in providing pointers to beneficial components of foods, as illustrated by the adverse effects apparent with smokers receiving beta-carotene supplementation, they are not necessarily able to predict actual effects and require confirmation in a defined human setting.
authors.affiliation: Department of Clinical Epidemiology, Osaka Medical Center for Cancer and Cardiovascular Diseases,Osaka 537, Japan. Cancer@gol.com
authors.forename: Hideki
authors.initials: H
authors.lastname: Ishikawa