Anhydramnios and maternal thrombocytopenia after prolonged use of nimesulide.
Prostaglandin synthesis inhibition have been proposed as an effective alternative to prevent preterm labour. This case report shows a pregnancy with anhydramnios and maternal thrombocytopenia, as side effects of the nimesulide therapy.
Paternoster
Delia M
DM
Department of Gynaecology and Human Reproduction, V Giustiniani 3, 35128 Padova, Italy. paternod@unipd.it
Snijders
Deborah
D
Manganelli
Francesca
F
Torrisi
Angela
A
Bracciante
Roberto
R
D000328:Adult; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D016104:Oligohydramnios / Q000139:chemically induced*; D011247:Pregnancy; D013449:Sulfonamides / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000139:chemically induced*
D016861:Cyclooxygenase Inhibitors; D013449:Sulfonamides; C012655:nimesulide