Using BNP to diagnose, manage, and treat heart failure.
A rapid assay for B-type natriuretic peptide (BNP) not only can be used to diagnose heart failure, it can help the clinician evaluate effectiveness of therapy, determine when discharge from the hospital is appropriate, and estimate prognosis. A synthetic formulation of BNP (nesiritide) is used to treat decompensated heart failure, resulting in improved hemodynamics and symptoms.
Hobbs
Robert E
RE
Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, The Cleveland Clinic, Cleveland Clinic Foundation, OH 44195, USA. hobbsr@ccf.org
D009320:Atrial Natriuretic Factor / Q000097:blood*; D006333:Heart Failure / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D045283:Natriuretic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use; D020097:Natriuretic Peptide, Brain; D011237:Predictive Value of Tests
D045283:Natriuretic Agents; D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor