title: [Sexual delinquency and Parkinson's disease].
abstract: The risk of aberrant sexual behaviour such as hypersexuality, exhibitionism, or pederasty may be underestimated in Parkinson's disease and its therapy with high-dosage L-dopa or dopamine agonists. We describe two legal cases which are representative of the forensic assessment of these side effects. The first case brought to court was a 45-year-old man suffering for 20 years from Parkinson's disease who developed hypersexuality and exhibitionism under high-dose therapy with ropinirol. The second patient, a 57-year-old man with an 11-year history of Parkinson's disease, developed increased libido and pederasty under therapy with L-dopa and bromocriptine. We discuss the present literature concerning hypersexuality and sexually deviant behaviour in Parkinson's disease and dopaminergic therapy in the German legal context. Doctors treating Parkinson patients should be aware of increased sexual impulses or reduced behavioural control and ask specifically about them during anamnesis, and counteractive therapeutic strategies should be considered to prevent the occurrence of illegal sexually aberrant behavioural disorders.
authors.affiliation: Neurologische Universitätsklinik, Heidelberg. christian_berger@med.uni-heidelberg.de
authors.forename: Ch
authors.initials: Ch
authors.lastname: Berger
authors.forename: F W
authors.initials: FW
authors.lastname: Mehrhoff
authors.forename: K M
authors.initials: KM
authors.lastname: Beier
authors.forename: H-M
authors.initials: HM
authors.lastname: Meinck
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001364:Awareness / Q000187:drug effects; D001971:Bromocriptine / Q000009:adverse effects / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005084:Exhibitionism / Q000139:chemically induced; D005104:Expert Testimony / Q000331:legislation & jurisprudence*; D006801:Humans; D007175:Impulsive Behavior / Q000139:chemically induced; D007211:Indoles / Q000009:adverse effects / Q000627:therapeutic use; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use; D007989:Libido / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D010378:Pedophilia / Q000139:chemically induced; D012742:Sex Offenses / Q000331:legislation & jurisprudence*
chemical_list: D000978:Antiparkinson Agents; D007211:Indoles; C046649:ropinirole; D001971:Bromocriptine; D007980:Levodopa
vernacular_title: Sexuelle Delinquenz und Morbus Parkinson.