title: Diagnostic imaging in lower limb atherosclerosis.
abstract: At present, there are a number of diagnostic imaging procedures for the evaluation of lower limb atherosclerosis. In particular, MR-angiography with contrast medium and multislice CT are rapidly developing. However, their role in clinical practice is still to be defined. In this article, first, the functional anatomy of peripheral arterial system divided into inflow arteries (aortoiliac trunk), outflow arteries (femoropoplietal trunk) and runoff arteries (leg and foot vessels), is examined. Then, image extraction with color-Doppler US, inflow MR-angiography with contrast material, multislice CT and angiography is briefly illustrated. The corresponding advantages and disadvantages, are indicated. The findings of combined imaging in relation to the various stages of atherosclerosis are analyzed. In particular, intimal thickening leading to occlusion is considered with respect to both morphology and flow alterations. Based on these considerations, the use of the different procedures is discussed in relation to the clinical presentation (no symptoms, claudication or pain, trophic lesions, during postoperative follow-up). For each stage, questions the radiologist should address for a correct approach and the best cost/benefit ratio, are described.
authors.affiliation: Istituto di Radiologia, Università Cattolica del S. Cuore, Policlinico A. Gemelli, Largo A. Gemelli 8,00168 Roma, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Di Stasi
authors.forename: A
authors.initials: A
authors.lastname: Cina
authors.forename: R
authors.initials: R
authors.lastname: Manfredi
authors.forename: S
authors.initials: S
authors.lastname: Colafati
mesh_terms: D001161:Arteriosclerosis / Q000175:diagnosis*; D003287:Contrast Media; D003952:Diagnostic Imaging; D006801:Humans; D007866:Leg / Q000098:blood supply*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis*
chemical_list: D003287:Contrast Media