title: Macular thickness measurements in healthy subjects with different axial lengths using optical coherence tomography.
abstract: OBJECTIVE
  To evaluate the retinal thickness of the macula in healthy subjects with different axial lengths.
  
  
  METHODS
  Included were 203 healthy subjects (116 males and 87 females). The axial length of the eyes ranged from 22.68 to 30.22 mm. Four optical coherence tomograms were obtained in a radial spoke pattern centered on the central fovea. Retinal thickness was calculated from the inner and outer retinal boundaries. The average retinal thickness in three circular areas surrounding the central fovea (350, 1,850, and 2,850 microm in diameter) was determined.
  
  
  RESULTS
  The retinal thickness in the three circular areas was not significantly correlated with the axial length of the eye (P = 0.10, P = 0.39, and P = 0.12). There also was no statistically significant difference found between the average thickness in emmetropic and low myopic, mildly myopic, and highly myopic eyes in the three circular areas (P = 0.35, P = 0.38, and P = 0.14).
  
  
  CONCLUSIONS
  When eyes with pathologic myopia were excluded, the axial length of the eye was found not to influence the average retinal thickness in the macular area.
authors.affiliation: Department of Ophthalmology, Mie University School of Medicine, Tsu Mie, Japan.
authors.forename: Yoshikatsu
authors.initials: Y
authors.lastname: Wakitani
authors.forename: Mikio
authors.initials: M
authors.lastname: Sasoh
authors.forename: Masahiko
authors.initials: M
authors.lastname: Sugimoto
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Ito
authors.forename: Masashi
authors.initials: M
authors.lastname: Ido
authors.forename: Yukiyaka
authors.initials: Y
authors.lastname: Uji
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007368:Interferometry; D008027:Light; D008266:Macula Lutea / Q000033:anatomy & histology* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000145:classification / Q000473:pathology; D012016:Reference Values; D012737:Sex Factors; D014054:Tomography