Upper gastrointestinal cancer risk in familial adenomatous polyposis.
Familial adenomatous polyposis has a known risk of colorectal carcinoma. Less well recognized, however, is the association with duodenal polyps and their subsequent malignant degeneration. While frequent endoscopic surveillance is acceptable, a case of early malignant transformation is presented, and the argument for prophylactic preemptive pancreaticoduodenectomy is made.
Wieman
T Jeffery
TJ
Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.
Taber
Scott W
SW
Reed
Donald N
DN
Vitale
Gary C
GC
D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000601:surgery; D000328:Adult; D005770:Gastrointestinal Neoplasms / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012306:Risk