title: "Difficult-to-treat depression".
authors.forename: David J
authors.initials: DJ
authors.lastname: Kupfer
authors.forename: Dennis S
authors.initials: DS
authors.lastname: Charney
mesh_terms: D001714:Bipolar Disorder / Q000188:drug therapy / Q000628:therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D004351:Drug Resistance; D006801:Humans