Determination of peak serum levels and immune response to the humanized anti-ganglioside antibody-interleukin-2 immunocytokine.
Hank
Jacquelyn A
JA
Comprehensive Cancer Center, Department of Human Oncology, University of Wisconsin, Madison, WI, USA.
Surfus
Jean E
JE
Gan
Jacek
J
Ostendorf
Amy
A
Gillies
Stephen D
SD
Sondel
Paul M
PM
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis / Q000276:immunology; D000920:Antibody-Dependent Cell Cytotoxicity; D019921:Biotinylation; D016207:Cytokines / Q000097:blood* / Q000276:immunology / Q000493:pharmacokinetics; D016503:Drug Delivery Systems; D004797:Enzyme-Linked Immunosorbent Assay; D005732:Gangliosides / Q000378:metabolism; D006207:Half-Life; D006801:Humans; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D051379:Mice; D012680:Sensitivity and Specificity; D013048:Specimen Handling
D000888:Antibodies, Anti-Idiotypic; D016207:Cytokines; D005732:Gangliosides; C019403:ganglioside, GD2