title: Eosinophils and eosinophil products in asthma.
abstract: Eosinophils are known to be an indirect marker of airway inflammation in asthma. It is known since long that the total eosinophil count reflects asthmatic activity and is useful for regulating steroid dosage and for early detection of exacerbations. Eosinophils are currently regarded as the effector cells responsible for much of the pathology of asthma. Eosinophil-mediated damage to the respiratory epithelium is a major pathogenetic mechanism in asthma. This article is a review of the latest works about the relationship of eosinophil and eosinophil products with asthma.
authors.affiliation: Department of Pulmonology, Military Hospital, Pakistan.
authors.forename: Waseem
authors.initials: W
authors.lastname: Saeed
authors.forename: Ahmed
authors.initials: A
authors.lastname: Badar
authors.forename: M Mazhar
authors.initials: MM
authors.lastname: Hussain
authors.forename: Muhammad
authors.initials: M
authors.lastname: Aslam
mesh_terms: D017209:Apoptosis; D001249:Asthma / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D001798:Blood Proteins / Q000502:physiology; D047091:Eosinophil Granule Proteins; D004804:Eosinophils / Q000502:physiology*; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D007958:Leukocyte Count; D012260:Ribonucleases
chemical_list: D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D012260:Ribonucleases