title: Habitual exercise and the age-associated decline in large artery compliance.
abstract: The compliance of the large elastic arteries in the cardiothoracic circulation declines with age, causing a number of adverse effects on cardiovascular function and disease risk. Recent findings indicate that regular aerobic exercise may favorably modulate age-associated decreases in central arterial compliance and the related adverse physiological and pathophysiological consequences.
authors.affiliation: Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, USA. seals@spot.colorado.edu
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Seals
mesh_terms: D000375:Aging / Q000502:physiology; D001011:Aorta; D001158:Arteries / Q000502:physiology*; D017704:Baroreflex / Q000502:physiology; D001775:Blood Circulation / Q000502:physiology; D002339:Carotid Arteries / Q000502:physiology; D003187:Compliance; D004548:Elasticity; D015444:Exercise / Q000502:physiology*; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D010807:Physical Endurance / Q000502:physiology; D016277:Ventricular Function, Left