title: Highly enantioselective quinoline synthesis via ene-type cyclization of 1,7-enynes catalyzed by a cationic BINAP-palladium(II) complex.
abstract: The first highly enantioselective synthesis of a six-membered ring quinoline catalyzed by a cationic BINAP-palladium(II) complex is shown to afford the quinoline products having a quaternary carbon center or a spiro-ring in quantitative yield and >99% ee.
authors.affiliation: Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152-8552, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Hatano
authors.forename: Koichi
authors.initials: K
authors.lastname: Mikami
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D009281:Naphthalenes / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis*; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D000480:Alkynes; C406943:BINAP, 2-naphthol; D009281:Naphthalenes; D009942:Organometallic Compounds; D011804:Quinolines; D010165:Palladium