title: Determination of absolute structure of macroviracins by chemical synthesis.
abstract: The relative and absolute configurations of macroviracins have been established by the stereocontrolled synthesis of methyl ester 2a of the C(22) carboxylic acid, a constitutive fatty acid of macroviracin A (1), and their comparison to a sample 2 derived from the natural product 1. [structure: see text]
authors.affiliation: RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama 351-0198, Japan. shunyat@postman.riken.go.jp
authors.forename: Shunya
authors.initials: S
authors.lastname: Takahashi
authors.forename: Moritoshi
authors.initials: M
authors.lastname: Hosoya
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Koshino
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nakata
mesh_terms: D005227:Fatty Acids / Q000138:chemical synthesis / Q000737:chemistry*; D046911:Macromolecular Substances; D009844:Oligosaccharides / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry
chemical_list: D005227:Fatty Acids; D046911:Macromolecular Substances; D009844:Oligosaccharides; C476171:macroviracin A