Hypothesis of regulation of hip joint cartilage activity by mechanical loading.
Hypothesis of regulation of proteosynthetic activity of chondrocytes is suggested. A deformation of the cartilage caused by contact hip joint stress and consequent deformation of the chondrocytes are considered as main factors that could influence the metabolism of the cartilage.
Daniel
Matej
M
Laboratory of Biomechanics of Man, Czech Technical University in Prague, Technická 4, Prague, Czech Republic.
Sochor
Miroslav
M
Iglic
Ales
A
Kralj-Iglic
Veronika
V
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D002358:Cartilage, Articular / Q000502:physiology*; D019902:Chondrocytes / Q000502:physiology*; D006621:Hip Joint / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D040542:Mechanotransduction, Cellular / Q000502:physiology*; D008954:Models, Biological; D013314:Stress, Mechanical; D016474:Weight-Bearing / Q000502:physiology*