Disseminated cytomegalovirus disease as a cause of prolonged fever in a bullous pemphigoid patient under systemic steroid therapy.
We present the first reported case of disseminated cytomegalovirus (CMV) in association with prednisone therapy in bullous pemphigoid (BP). A 66-year-old black male patient was admitted to our hospital presenting cutaneous pruritic lesions represented by tense blisters, with serous content on the arms, abdomen and legs. Laboratory findings confirmed the diagnosis of BP. After two weeks of prednisone therapy, the patient developed prolonged fever, which was caused by CMV disseminated disease, with prompt clinical recovery after ganciclovir administration.
Casals
Daniel Sesto
DS
Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil.
Nunes
Eduardo de Azevedo
Ede A
Maruta
Celina Wakisaka
CW
Aoki
Valeria
V
Santi
Claudia Giuli
CG
Simonsen Nico
Marcello Menta
MM
Correa
Maria Cassia Mendes
MC
Leite
Olavo Henrique Munhoz
OH
Rivitti
Evandro A
EA
D000368:Aged; D001707:Biopsy, Needle; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D005334:Fever / Q000150:complications* / Q000175:diagnosis; D005500:Follow-Up Studies; D015774:Ganciclovir / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D008297:Male; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D011241:Prednisone / Q000008:administration & dosage* / Q000009:adverse effects; D018570:Risk Assessment; D016896:Treatment Outcome
D015774:Ganciclovir; D011241:Prednisone