[Study of storage stability of the commercial series of thromboplastin preparations].
The stability of commercial series of the thromboplastin preparation (obtained from rabbit brain) with calcium (TKS, Researach-and-Production Enterprise "Renam" MICH 1.1-1.2), of TKS "Tromborel" and of "Immunoplastin" (Technoclon) was comparatively studied. TKS "Renam" preserved its activity and sensitivity to factor VII in the liophilizated state for as long as 6 months. The preparations of "Renam", TKS, preserved the stable activity in the reconstructed liquid state, under the conditions of continuous storage, at 37 degrees C for 2 days, at 18-20 degrees C--for 2-3 days, and at 2-8 degrees C--for 5-7 days, which was accompanied by a stable high sensitivity to factor VII. The stability of the "Renam", TKS, was found to be similar to that of imported preparations.
Berkovskiĭ
A L
AL
Ul'ianova
I S
IS
Sergeeva
E V
EV
Gradova
Iu A
IuA
Balamedova
I A
IA
Suvorov
A V
AV
D000818:Animals; D004356:Drug Storage; D006490:Hemostatics / Q000737:chemistry*; D011817:Rabbits; D013696:Temperature; D013925:Thromboplastin / Q000737:chemistry*; D013997:Time Factors
D006490:Hemostatics; D013925:Thromboplastin
Issledovanie stabil'nosti promyshlennykh seriĭ preparatov tromboplastina pri khranenii.