[Adverse reactions and quality of life].
Several studies evaluated the impact of chronic hepatitis C on the patient's quality of life. The findings show that chronic HCV infection affects life quality, independently of the severity of the hepatitis. Quality of life improves when the virus is eliminated. Adverse reactions of the monotherapy with interferon or combination therapy with ribavirin can be added to the debilitating effects of the disease itself. Impact on the quality of life may be even greater with a program that includes frequent doses of standard interferon. Preliminary data, reported as abstracts and as complete documents, suggest that pegylated interferon has better results during and after treatment as far as quality of life is concerned. The comparison was made with interferon a2a alone and with interferon a2b plus ribavirin.
Trejo Estrada
Rafael
R
Departamento de Gastroenterología, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, IMSS. Ave. Cuauhtémoc No. 330, Col. Doctores, Deleg. Cuauhtémoc, 06720 México, D.F.
D000998:Antiviral Agents / Q000009:adverse effects; D006526:Hepatitis C / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007372:Interferons / Q000009:adverse effects; D011788:Quality of Life
D000998:Antiviral Agents; D007372:Interferons
Reacciones adversas y calidad de vida.