[The effect of organism environment on bacteriostatic and mechanical properties of Palacos R cement mixed with antibiotic].
The results of bacteriological tests of Palacos R cement with antibiotic directly after its obtaining and 3 and 6 months after implantation in rabbit organism have been presented in this work. The results of tests of mechanical characteristics of cement with and without antibiotic samples after being kept in physiological saline for 3 to 6 weeks have also been presented. Bacteriological tests prove that antibiotic (III generation cephalosporin) added to surgical cement retain its bacteriostatic properties. When tested on rabbits cement plus antibiotic retains its bacteriostatic properties only in the initial period. Kep of the Palacos R cement with and without III generation cephalosporin in physiological saline insignificantly decreased the strength properties as compared to respective values of dry cement strength and did not lead to any loss of its visco-elasticity.
Toborek
Jerzy
J
Oddział Urazowo-Ortopedyczny, Szpital Miejski nr 2 w Siemianowicach Slaskich.
Gajda
Zbigniew
Z
Balin
Alicja
A
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001843:Bone Cements / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002443:Ceftriaxone / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D008422:Materials Testing / Q000379:methods; D019904:Polymethyl Methacrylate / Q000493:pharmacokinetics*; D016459:Prosthesis-Related Infections / Q000517:prevention & control*; D011817:Rabbits; D013314:Stress, Mechanical; D013718:Tensile Strength; D013997:Time Factors
D000900:Anti-Bacterial Agents; D001843:Bone Cements; D002443:Ceftriaxone; D019904:Polymethyl Methacrylate
Wpływ środowiska organizmu na właściwości bakteriostatyczne i mechaniczne cementu Palacos R z domieszka antybiotyku.