[HLA typing in twins with vesicoureteral reflux].
We treated 2 cases of vesicoureteral reflux (VUR) in twins. Case 1: A 6-year-old girl had grade 3 VUR on the right side and grade 1 VUR on the left side. Case 2: A 5-year-old girl, the younger sister of case 1, had grade 4 VUR on the right side. We treated these patients with bilateral anti-reflux-therapy (Cohen's method). We analyzed the HLA ABC locus in this family and found that these twins and their mother (who had been treated for bilateral VUR in childhood) were of the same haplotype, but not a haplotype previously reported. We believe that familial VUR should be aggressively investigated.
Nose
Kazuhiro
K
Department of Urology, Kinki University of Medicine.
Hanai
Tadashi
T
Sugiyama
Takahide
T
Kurita
Takashi
T
Kajikawa
Hiroshi
H
Kataoka
Kiyonori
K
D002648:Child; D002675:Child, Preschool; D004200:Diseases in Twins; D005192:Family Health; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D014429:Twins, Dizygotic; D014718:Vesico-Ureteral Reflux / Q000235:genetics* / Q000601:surgery
D006680:HLA Antigens