The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya I. Development of infrastructure and description of study site.
Randomized controlled trials in sub-Saharan Africa have shown that permethrin-treated bed nets and curtains reduce all-cause child mortality by 15-33% in areas with low or high but seasonal malaria transmission. This report describes the study site for a community-based, group-randomized, controlled trial in an area of high and year-round malaria transmission in western Kenya. We outline the development of the human and physical infrastructure required to conduct this trial and discuss some of the difficulties encountered and lessons learned in conducting it.
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Penelope A
PA
Phillips-Howard
Bernard L
BL
Nahlen
Jane A
JA
Alaii
Feiko O
FO
ter Kuile
John E
JE
Gimnig
Dianne J
DJ
Terlouw
S Patrick
SP
Kachur
Allen W
AW
Hightower
Altaf A
AA
Lal
Erik
E
Schoute
Aggrey J
AJ
Oloo
William A
WA
Hawley
D001512:Bedding and Linens; D044383:Black People; D002648:Child; D002980:Climate; D005006:Ethnicity; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D007630:Kenya / Q000453:epidemiology; D008288:Malaria / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D009017:Morbidity; D015337:Multicenter Studies as Topic; D026023:Permethrin / Q000494:pharmacology*; D011891:Rain
D007306:Insecticides; D026023:Permethrin