Use of sodium chloride to facilitate reduction of particle size of dexamethasone during ball milling.
Apte
Shireesh P
SP
Alcon Research, Inc., Process Research and Support, Fort Worth, Texas 76134, USA. shireesh.apte@alconlabs.com
Cagle
Mike
M
Bryant
Ronald
R
Weidenbach
Annita
A
Kulshreshtha
Alok K
AK
D001548:Benzalkonium Compounds / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D003907:Dexamethasone / Q000737:chemistry*; D004339:Drug Compounding; D005079:Excipients / Q000737:chemistry; D008353:Mannitol / Q000737:chemistry; D010316:Particle Size; D011136:Polysorbates / Q000737:chemistry; D012965:Sodium Chloride / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry; D013535:Suspensions / Q000737:chemistry
D001548:Benzalkonium Compounds; D005079:Excipients; D011136:Polysorbates; D013501:Surface-Active Agents; D013535:Suspensions; D008353:Mannitol; D012965:Sodium Chloride; D003907:Dexamethasone