Studies of five microelement contents in human serum, hair, and fingernails correlated with aged hypertension and coronary heart disease.
Using atomic absorption spectrometry (AAS), five microelements in human serum, hair, and fingernails of aged hypertension, coronary heart disease (diseased group) and aged health control (healthy group) were detected. Results of the t-test are as follows: The iron, zinc, and cadmium contents and Zn/Cu (mol/mol) ratio of the diseased group were significantly higher than that of the healthy group in serum (p<0.01, p<0.05, p<0.01, and p<0.05, respectively); the chromium contents in the serum, hair, and fingernails (p<0.05, p<0.01, and p<0.05, respectively); the iron and zinc contents in the hair and fingernails (p<0.01, p<0.001, p<0.05, and p<0.01 respectively) and Zn/Cu ratio in the hair (p<0.01) of the diseased group were significantly lower than that of the healthy group.
Tang
Yu-Rong
YR
College of Chemistry and Molecular Science, College of Life Sciences, Wuhan University, 430072 Wuhan Hubei, China.
Zhang
Shu-Qin
SQ
Xiong
Yin
Y
Zhao
Yu
Y
Fu
Hua
H
Zhang
Hua-Ping
HP
Xiong
Kai-Min
KM
D000368:Aged; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D002104:Cadmium / Q000032:analysis / Q000097:blood; D002857:Chromium / Q000032:analysis / Q000097:blood; D003327:Coronary Disease / Q000453:epidemiology*; D005260:Female; D005385:Fingers; D006197:Hair / Q000737:chemistry*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D007501:Iron / Q000032:analysis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000737:chemistry*; D012016:Reference Values; D013054:Spectrophotometry, Atomic; D014131:Trace Elements / Q000032:analysis* / Q000097:blood; D015032:Zinc / Q000032:analysis / Q000097:blood
D015415:Biomarkers; D014131:Trace Elements; D002104:Cadmium; D002857:Chromium; D007501:Iron; D015032:Zinc