Bioresorbable polymeric stents: current status and future promise.
Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory.
Department of Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry, Hines Boulevard, Dallas, TX 75390-9130, USA. robert.eberhart@utsouthwestern.edu
Robert C
RC
Eberhart
Shih-Horng
SH
Su
Kytai Truong
KT
Nguyen
Meital
M
Zilberman
Liping
L
Tang
Kevin D
KD
Nelson
Peter
P
Frenkel
D001673:Biodegradation, Environmental; D020099:Coated Materials, Biocompatible; D016503:Drug Delivery Systems; D006801:Humans; D011108:Polymers; D019919:Prosthesis Implantation; D015607:Stents / Q000639:trends*
D020099:Coated Materials, Biocompatible; D011108:Polymers