[Medical treatment of acute coronary syndrome without ST-segment elevation].
Unstable angina is the most frequent acute coronary syndrome. Risk stratification to predict coronary morbidity and mortality and the risk of major haemorrhage are the key steps of the medical approach. Combined antithrombotic therapy (including aspirin, clopidogrel, low-molecular weight heparins and, eventually glycoprotein IIb/IIIa receptor antagonists) has led to a substantial reduction of major coronary events with a good tolerance because of the short duration of such aggressive strategy. This combined antithrombotic also allowed to increase the benefit of an early invasive strategy including coronary angiogram with stent percutaneous coronary angioplasty.
Collet
Jean-Philippe
JP
Institut de cardiologie Groupe hospitalier La Pitié-La Salpêtrière 75651 Paris. jean-philippe.collet@psl.ap-hop-paris.fr
Choussat
Rémi
R
Montalescot
Gilles
G
D000208:Acute Disease; D000789:Angina, Unstable / Q000188:drug therapy* / Q000473:pathology; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003327:Coronary Disease / Q000188:drug therapy* / Q000473:pathology; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D009203:Myocardial Infarction / Q000517:prevention & control; D018570:Risk Assessment; D013577:Syndrome
D005343:Fibrinolytic Agents