Clinical findings in macular hole surgery with indocyanine green-assisted peeling of the internal limiting membrane.
OBJECTIVE
Indocyanine green (ICG) staining of the internal limiting membrane has facilitated ILM peeling in macular hole surgery. However, it has been reported that ICG-assisted peeling of the ILM may result in retinal damage and unfavorable functional outcome. Therefore, we analyzed our visual and anatomical results of ICG assisted macular hole surgery.


METHODS
In a retrospective study the records of a consecutive series of 37 patients with full-thickness idiopathic macular holes operated with ICG-assisted ILM peeling by a single surgeon were analyzed. All patients underwent a standard three-port vitrectomy with surgically induced posterior vitreous detachment, staining of the ILM with ICG, peeling of the ILM in a circular manner around the fovea, and SF6 20% endotamponade.


RESULTS
A total of 37 patients (37 eyes) were included in the study. The mean age was 69+/-7 years (range 52-81 years), and there were 26 women and 11 men. The follow-up ranged from 6 to 30 months (mean 18+/-6 months). At baseline visual acuity ranged from 20/400 to 20/40. Anatomically, 13 eyes had stage 2 holes, 21 eyes (57%) stage 3 holes, and three eyes stage 4 holes. At the postoperative visit (8-12 weeks after surgery) anatomical closure of the macular hole was achieved in 36 eyes. Visual acuity ranged between 20/400 and 20/20. At the last follow-up after initial surgery the macular hole was closed in all eyes. Visual acuity ranged from 20/200 to 20/20.


CONCLUSIONS
In our retrospective series anatomical and functional results of macular hole surgery with ICG-assisted peeling of the ILM are satisfactory. Primary hole closure was achieved in 97% of eyes and visual acuity increased in 62% of eyes in our series.
Klinik und Poliklinik für Augenheilkunde, Liebigstrasse 10-14, 04103 , Leipzig, Germany. wolfs@medizin.uni-leipzig.de.
S
S
Wolf
Klinik und Poliklinik für Augenheilkunde, Liebigstrasse 10-14, 04103 , Leipzig, Germany.
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MB
Reichel
Klinik und Poliklinik für Augenheilkunde, Liebigstrasse 10-14, 04103 , Leipzig, Germany.
P
P
Wiedemann
Klinik und Poliklinik für Augenheilkunde, Liebigstrasse 10-14, 04103 , Leipzig, Germany.
U E K
UEK
Schnurrbusch
D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D019773:Epiretinal Membrane / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D013194:Staining and Labeling; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy
D004396:Coloring Agents; D007208:Indocyanine Green