[Activity of the enzymatic antioxidant system depends on the clinical stage of laryngeal cancer ].
The goal of this study was to examine if there is any connection between enzymatic antioxidant system and larynx cancer staging. The levels of superoxide dysmutase, catalase and glutathione peroxidase, 6-phosphogluconic dehydrogenase and glucoso-6-phosphate dehydrogenase were measured in blood of 28 larynx cancer patients. The results show that the activity of this system is lower in sick patients than in healthy control group. It was becoming lower group of patients with more advanced cancer.
II Katedra i Oddział Kliniczny Laryngologii Slaskiej AM w Zabrzu.
Grzegorz
G
Namysłowski
Andrzej
A
Sobczak
Ewa
E
Uhma
D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D002374:Catalase / Q000097:blood; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D007822:Laryngeal Neoplasms / Q000201:enzymology* / Q000473:pathology*; D008297:Male; D010734:Phosphogluconate Dehydrogenase / Q000097:blood; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase