Management of neuromas.
After nerve injury and regeneration, significant pain may be associated with the scar and altered sensation observed within the distribution of the injured nerve. A bulbous swelling may form at the severed nerve end, constituting a traumatic neuroma. The development of a painful neuroma may be more disabling to the patient than an area of anesthesia or even loss of motor function. Effective treatment of the painful neuroma remains a difficult problem. Diminished productivity, alterations in patient lifestyle, and possible progression to chronic pain syndromes must be considered within the scope of neuroma management, and treatment must focus on alleviating the pain and restoring the functional loss caused by the nerve injury. Careful patient selection is the cornerstone of successful outcomes. Once the patient has been selected, the surgical management of the painful neuroma throughout the body is based on basic principles that vary only slightly from region to region. Using these tenets, a neuroma management algorithm has been developed based on the pathophysio-logy of the neuroma, the results of experimental studies, review of patient outcomes, and understanding the psychology of pain in the surgical patient.
Vernadakis
Adam J
AJ
Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, Suite 17424, East Pavilion, Box 8238, One Barnes-Jewish Hospital Plaza, St. Louis, MO 63110, USA.
Koch
Horst
H
Mackinnon
Susan E
SE
D005121:Extremities / Q000294:innervation*; D006801:Humans; D017169:Neoplasms, Post-Traumatic / Q000175:diagnosis / Q000601:surgery*; D009416:Nerve Regeneration; D009463:Neuroma / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000503:physiopathology / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications