Never fat or gaunt.
Bacteria stringently regulate the synthesis of their membrane phospholipids, but the responsible regulatory mechanisms are incompletely understood. In this issue of Developmental Cell, a study reports negative regulation of the transcription of several genes of fatty acid and phospholipid synthesis plus identification of the regulatory protein.
James
Ethan S
ES
Department of Microbiology, University of Illinois, Urbana, IL 61801, USA.
Cronan
John E
JE
D001412:Bacillus subtilis / Q000235:genetics / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D008563:Membrane Lipids / Q000096:biosynthesis*; D010743:Phospholipids / Q000096:biosynthesis*; D014157:Transcription Factors / Q000378:metabolism*
D029968:Escherichia coli Proteins; C067955:FAPR protein, E coli; D008563:Membrane Lipids; D010743:Phospholipids; D014157:Transcription Factors