[Severe diarrhea and eosinophilic colitis attributed to pinworms (Enterobius vermicularis)].
In a 32-year-old woman suffering from severe diarrhoea, eosinophilic infiltration of colonic mucosa and a peripheral eosinophilia, microbiological investigations only revealed large numbers of Enterobius vermicularis (pinworm) in the faeces. Treatment with mebendazole resulted in a rapid resolution of symptoms and disappearance of the eosinophilia, which strongly suggested a causative role of this pinworm in the clinical syndrome of the patient. E. vermicularis is generally regarded as an innocent nematode, which at most causes perianal pruritus due to migration of worms from the colon and expulsion of eggs onto the perianal skin. Although the pinworm maturates and lives in the gut, gastrointestinal symptoms have seldom been reported. E. vermicularis infection should be considered in patients with unexplained eosinophilic enteritis.
Academisch Medisch Centrum, afd. Medische Microbiologie, Postbus 22.660, 1100 DD Amsterdam. m.d.dejong@amc.uva.nl
M D
MD
de Jong
J
J
Baan
E
E
Lommerse
T
T
van Gool
D000328:Adult; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D003092:Colitis / Q000188:drug therapy / Q000469:parasitology*; D003967:Diarrhea / Q000188:drug therapy / Q000469:parasitology*; D017229:Enterobiasis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004757:Enterobius / Q000302:isolation & purification; D004802:Eosinophilia / Q000188:drug therapy / Q000469:parasitology*; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008463:Mebendazole / Q000627:therapeutic use
D000969:Antinematodal Agents; D008463:Mebendazole