Anti-inflammatory activity of a novel flavonol glycoside from the Bauhinia variegata Linn.
Bauhinia variegata Linn. (Leguminosae) is commonly known as 'Kachnar' in Hindi. It is distributed almost throught India. Its powdered bark is traditionally used for tonic, astrain, ulcers. It is also useful in skin diseases. The roots are used as antidote to snake poison. The present article deals with the isolation and structural elucidation of a novel flavonol glycoside 5,7,3',4'-tetrahydroxy-3-methoxy-7-O-alpha-L-rhamnopyranosyl(1-->3)-O-beta-galactopyranoside (1) from the roots of Bauhinia Variegata and its structure was identified by spectral analysis and chemical degradations. The novel compound (1) showed anti-inflammatory activity.
Yadava
R N
RN
Natural Products Laboratory, Department of Chemistry, Dr. H.S. Gour University, Sagar (M.P.) 470003, India. rnyadava@rediffmail.com
Reddy
V Madhu Sudhan
VM
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D036481:Bauhinia / Q000737:chemistry*; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007249:Inflammation / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats
C479402:5,7,3',4'-tetrahydroxy-3-methoxy-7-O-rhamnopyranosyl-1-3-galactopyranoside; D000893:Anti-Inflammatory Agents; D004187:Disaccharides; D005419:Flavonoids