The role of intraoperative device closure in the management of muscular ventricular septal defects.
The contemporary surgical management of multiple ventricular septal defects (VSDs) carries a relatively high mortality rate in comparison to that of other biventricular repairs. Several innovative approaches have been recommended for repair of multiple VSDs, but none are uniformly successful in achieving complete elimination of ventricular shunting without causing ventricular dysfunction. This is especially true in cases with highly deficient ventricular septa, the so-called "Swiss cheese" anomaly. The recent introduction of the CardioSEAL (NMT Medical Inc, Boston, MA) double-clamshell device led to an evaluation of intraoperative device-mediated closure of muscular VSDs. Taken in context with our overall experience in the surgical management of multiple VSDs, we suggest that device-mediated closure of muscular VSDs is a useful and potentially ventricular function-sparing option for this challenging problem.
Hospital for Sick Children, University of Toronto, Toronto, Canada.
Igor E
IE
Konstantinov
John G
JG
Coles
D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods; D006348:Cardiac Surgical Procedures / Q000295:instrumentation* / Q000379:methods; D002675:Child, Preschool; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D006346:Heart Septum / Q000473:pathology / Q000601:surgery*; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007432:Intraoperative Period; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013525:Surgical Instruments; D015996:Survival Rate; D013536:Suture Techniques; D016896:Treatment Outcome