Molluscicidal and antimicrobial activity of Solanum aculeastrum.
The methanolic extract of the fresh root bark and berries of Solanum aculeastrum showed significant activity against host snails of schistosomiasis. The berries extract was more potent with 100% snail kill at 50 ppm. Fractionation increased activity with 100% mortality at 20 ppm. The aqueous and methanolic extracts of the berries showed moderate antimicrobial activity, increasing by fractionation.
Kenyatta University, Chemistry Department, PO Box 43844, Nairobi, Kenya.
Alphonse W
AW
Wanyonyi
Sumesh C
SC
Chhabra
Gerald
G
Mkoji
Wilson
W
Njue
Paul K
PK
Tarus
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001700:Biomphalaria / Q000187:drug effects*; D005638:Fruit; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008975:Molluscacides / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D012552:Schistosomiasis / Q000188:drug therapy; D032322:Solanum
D000900:Anti-Bacterial Agents; D008975:Molluscacides; D010936:Plant Extracts