[Carcinomatous transformation of an atypical polypoid adenomyofibroma of the uterus].
We report a case of an atypical polypoid adenomyofibroma (APA) with carcinomatous transformation that occurred in a nulliparous 32 year-old woman treated with estroprogestatives. The well-differentiated mucinous adenocarcinoma was in continuity with the APA, showed a deep myoinvasion and extended to the upper part of the cervix. No hormonal receptor was expressed by tumor cells. Because of the risk of carcinomatous transformation, complete excision of APA(s) is warranted.
Service d'Anatomie et de Cytologie Pathologiques, Hôpital Edouard Herriot, Lyon..
Annie
A
Buénerd
Daniel
D
Dargent
Jean-Yves
JY
Scoazec
Gérard
G
Berger
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D018194:Adenomyoma / Q000473:pathology*; D000328:Adult; D002471:Cell Transformation, Neoplastic; D004967:Estrogens / Q000008:administration & dosage; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D011372:Progestins / Q000008:administration & dosage; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery
D004967:Estrogens; D011372:Progestins