A comparison of the efficacy of alfentanil and remifentanil analgesic infusions for spinal surgery.
The use of alfentanil infusion was compared with that of remifentanil infusion for spinal cord surgery in a retrospective review. The aim was to compare the outcome when methohexitone was used as the only hypnotic agent in the two groups. Over a 3-year period, 5 patients (group 1) had Alfentanil infusion and 11 patients (group 2) had remifentanil infusion for analgesia during spinal cord surgery. Results showed that remifentanil lead to a faster onset of recorvery than alfentanil. It also provided better haemodynamic stability than alfentanil without excesive hypotension (p > 0.05). Our experience here indicated that remifentanil provided better flexibility of use with less tachycardia and respiratory depression than alfentanil for spinal surgery.
Department of Anaesthesia, Obafemi Awolowo University, Ile-Ife, Nigeria.
A F
AF
Faponle
J W H
JW
Watt
D000328:Adult; D015760:Alfentanil / Q000494:pharmacology / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000494:pharmacology / Q000627:therapeutic use*; D000762:Anesthesia Recovery Period; D018686:Anesthetics, Intravenous / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control; D010880:Piperidines / Q000494:pharmacology / Q000627:therapeutic use*; D000077208:Remifentanil; D012131:Respiratory Insufficiency / Q000139:chemically induced; D012189:Retrospective Studies; D013118:Spinal Cord Diseases / Q000601:surgery*; D013610:Tachycardia / Q000139:chemically induced; D013997:Time Factors; D016896:Treatment Outcome; D015300:Ventilator Weaning
D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D010880:Piperidines; D015760:Alfentanil; D000077208:Remifentanil