Room-temperature Hiyama cross-couplings of arylsilanes with alkyl bromides and iodides.
The first method for achieving Hiyama couplings of unactivated alkyl bromides and iodides is reported. The desired carbon-carbon bond formation proceeds under mild conditions (room temperature) with good functional-group tolerance.
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Jae-Young
JY
Lee
Gregory C
GC
Fu
D002384:Catalysis; D006838:Hydrocarbons / Q000138:chemical synthesis*; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D012821:Silanes / Q000737:chemistry*; D013696:Temperature
D006838:Hydrocarbons; D006842:Hydrocarbons, Brominated; D006847:Hydrocarbons, Iodinated; D012821:Silanes; D010165:Palladium