[Effect of Zingiber OfficinaleRosc on lipid peroxidation in hyperlipidemia rats].
Zingiber Officinale Rosc(ginger) is the food of rhizoma species as well as Chinese traditional medicine and has various pharmacological effects. The last researches showed that ginger not only reduced plasma lipid levels but also the mouse atherosclerotic lesion areas. The ginger antioxidative effect maybe pay an important role in attenuation of development of atherosclerosis. Antioxidative effect of Zingiber Officinale Rosc on hyperlipidemia rats have been studied and the changes of GSH-Px and LPO in their blood have been observed in this paper. Male adult Wistar rats were grouped into control, preventive and curative teams. The experimental teams were respectively fed on the test diet containing 2% ginger and 5% ginger, in order to measure the changes of plasma lipid peroxides (LPO) and glutathione (GSH-Px) after the experiment. The results show that ginger increased GSH-Px and reduced LPO in the rats' blood. Ginger could inhibit and/or scaving radicals of rat body in different degrees.
School of Food Science, Northeast Agricultural University, Harbin 150030, China.
Ning
N
Liu
Guicheng
G
Huo
Ling
L
Zhang
Xueyan
X
Zhang
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology; D020939:Zingiber officinale; D005979:Glutathione Peroxidase / Q000097:blood; D006949:Hyperlipidemias / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D008054:Lipid Peroxides / Q000097:blood; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D008054:Lipid Peroxides; D005979:Glutathione Peroxidase