MCID/Low Disease Activity State Workshop: low disease activity state in rheumatoid arthritis.
The MCID (minimal clinically important difference) module of OMERACT 5 developed a research agenda that led to the conclusion that a state of low disease activity for rheumatoid arthritis (RA) would need to be defined. To develop such a definition the various concepts and terminologies, the process for developing an operational definition, and the availability and design of longitudinal datasets for validation needed to be considered. This article describes the process of the MCID/Low Disease Activity State Workshop at OMERACT 6 to develop such a definition.
Department of Clinical Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada.
George
G
Wells
Maarten
M
Boers
Beverley
B
Shea
Jennifer
J
Anderson
David
D
Felson
Kent
K
Johnson
John
J
Kirwan
Marissa
M
Lassere
Vivian
V
Robinson
Lee
L
Simon
Vibeke
V
Strand
Piet
P
van Riel
Peter
P
Tugwell
D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D017063:Outcome Assessment, Health Care; D012074:Remission Induction; D012720:Severity of Illness Index