Transitional cell papilloma of the penis associated with human papilloma virus infection. Report of two cases.
Condylomas are one of the most common human papilloma virus (HPV)-related benign lesions of the male genitourinary tract. Although rarely, HPV has also been detected along the urinary tract, using molecular techniques, in transitional cell neoplasms without microscopic signs of koilocytic atypia. When affecting the urethra, condylomas are usually limited to its third distal portion. However, transitional cell neoplasms of the urethra are exceptional and in most of the cases remain limited to its proximal portion. To the best of our knowledge, 12 cases of transitional cell carcinomas and only one case of typical transitional cell papilloma have been described in the anterior urethra. We report two exceptional cases of typical transitional cell papilloma of the glans of the penis near the fossa navicularis which showed microscopic signs of HPV infection.
Rodríguez-Pinilla
Socorro María
SM
Department of Pathology 12 de Octubre, University Hospital, 28041, Madrid, Spain.
Rodríguez-Peralto
José Luis
JL
Férnandez-Figueras
María Teresa
MT
D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000473:pathology* / Q000821:virology; D027383:Papillomaviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications / Q000473:pathology*; D010412:Penile Neoplasms / Q000473:pathology* / Q000821:virology; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000150:complications / Q000473:pathology*
D004279:DNA, Viral