Dual role of organosulfur compounds in foods: a review.
Organosulfur compounds present in natural food are generally considered as beneficial for health because of their antioxidant and anticarcinogenic properties. This has led to their excessive and long-term consumption. However, there is also evidence that these compounds demonstrate toxicity and adverse health effects suggesting their potential dual biological roles. Thus, they can act as double-edged biological swords.
Division of In Vitro and Biochemical Toxicology, Office of Applied Research and Safety Assessment, U.S. Food and Drug Administration, Laurel, MD 20708, USA. Saura.Sahu@cfsan.fda.gov
Saura C
SC
Sahu
D000975:Antioxidants / Q000494:pharmacology*; D002273:Carcinogens / Q000378:metabolism / Q000494:pharmacology*; D002318:Cardiovascular Diseases / Q000503:physiopathology; D005502:Food; D006801:Humans; D009153:Mutagens / Q000378:metabolism; D017382:Reactive Oxygen Species; D013457:Sulfur Compounds / Q000009:adverse effects* / Q000494:pharmacology*
D000975:Antioxidants; D002273:Carcinogens; D009153:Mutagens; D017382:Reactive Oxygen Species; D013457:Sulfur Compounds