Antihyperglycemic activity of Caralluma attenuata.
Extracts of Caralluma attenuata are screened for their antihyperglycemic activity. Ethanol, chloroform and butanol extracts were tested on glucose loaded and alloxan-induced diabetic rats. In both tests, the butanol extract, at the oral dose of 250 mg/kg, has shown statistically significant and considerable antihyperglycemic activity.
G Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad 500 028, India. venkateshsama@hotmail.com
S
S
Venkatesh
G Dayanand
GD
Reddy
B Madhava
BM
Reddy
M
M
Ramesh
A V N Appa
AV
Rao
D000284:Administration, Oral; D000496:Alloxan; D000818:Animals; D029062:Apocynaceae; D001786:Blood Glucose / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy; D005951:Glucose Tolerance Test; D006943:Hyperglycemia / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000496:Alloxan