Investigation of a rubella outbreak in Kyrgyzstan in 2001: implications for an integrated approach to measles elimination and prevention of congenital rubella syndrome.
In 1999, the Ministry of Health of Kyrgyzstan adopted the goal of measles elimination. This opportunity was used to launch a rubella and congenital rubella syndrome prevention program. Between January and August 2001, a rubella outbreak occurred in Bishkek City and Chui Oblast. Rubella surveillance data were reviewed for Kyrgyzstan (1981-2000) and rubella case-patient and laboratory information from Bishkek City and Chui Oblast during the outbreak. The data suggest that rubella is endemic in Kyrgyzstan with periodic epidemics every 3-5 years. From January to August 2001, 1936 rubella case-patients were reported from Bishkek City and Chui Oblast; 242 were tested and 176 (73%) were laboratory confirmed. Most case-patients were 3-14 years old. However, the incidence rate per 100,000 among persons aged 15-35 years increased >/=40-fold from 1 in 2000 to 41 in 2001. These findings highlight the importance of introducing rubella-containing vaccine in conjunction with measles elimination activities.
Dayan
Gustavo H
GH
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. gdayan@cdc.gov
Zimmerman
Laura
L
Shteinke
Ludmila
L
Kasymbekova
Kalya
K
Uzicanin
Amra
A
Strebel
Peter
P
Reef
Susan
S
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007707:Kyrgyzstan / Q000453:epidemiology; D008297:Male; D011159:Population Surveillance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D012409:Rubella / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D012410:Rubella Syndrome, Congenital / Q000517:prevention & control*; D016036:Seroepidemiologic Studies; D014505:Urban Population
D000914:Antibodies, Viral