Efficient epoxidation of electron-deficient olefins with a cationic manganese complex.
The complex [MnII(R,R-mcp)(CF3SO3)2] is an efficient and practical catalyst for the epoxidation of electron-deficient olefins. This catalyst is capable of epoxidizing olefins with as little as 0.1 mol % catalyst in under 5 min using 1.2 equiv of peracetic acid as the terminal oxidant. A wide scope of substrates are epoxidized including terminal, tertiary, cis and trans internal, enones, and methacrylates with >85% isolated yields.
Department of Chemistry, Stanford University, Stanford, California 94305, USA.
Andrew
A
Murphy
Geraud
G
Dubois
T D P
TD
Stack
D000475:Alkenes / Q000737:chemistry*; D002412:Cations / Q000737:chemistry; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000138:chemical synthesis*; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry
D000475:Alkenes; D002412:Cations; D004852:Epoxy Compounds; D009942:Organometallic Compounds; D008345:Manganese