Near-fatal grape aspiration with complicating acute lung injury successfully treated with extracorporeal membrane oxygenation.
OBJECTIVE
In this report of a near-fatal case of grape aspiration successfully treated with extracorporeal membrane oxygenation (ECMO), we highlight the danger of feeding seedless grapes to young children and demonstrate that ECMO can provide cardiopulmonary support for cases of acquired large-airway disruption and can facilitate therapeutic intervention.


METHODS
Case report.


METHODS
A tertiary pediatric intensive care unit and ECMO center.


METHODS
A healthy 14-month-old boy aspirated a seedless grape while playing at home and suffered a cardiopulmonary arrest of 15 mins in duration. He responded to advanced life support with return of cardiac output but developed intractable cardiopulmonary failure secondary to aspirated grape particles and postobstructive pulmonary edema.


METHODS
The patient was emergently transferred to the regional ECMO center and placed on venoarterial ECMO. Bronchoscopies were performed in the stable environment provided by ECMO, aspirated particles were removed from the large airways, and lung recovery was facilitated.


RESULTS
End-organ perfusion was restored via ECMO during a period of severe intractable cardiopulmonary failure. Pulmonary recovery occurred during a 6-day ECMO run and was facilitated by therapeutic bronchoscopy. The patient was reviewed 1 yr later and has made a full neurodevelopmental recovery, despite a 15-min out-of-hospital cardiac arrest.


CONCLUSIONS
Aspiration of a seedless grape is a life-threatening event in a small child. This danger is not fully appreciated by parents in the UK. ECMO may be life saving in cases of acquired large-airway disruption resulting in severe cardiopulmonary failure, including foreign body aspiration, as long as end-organ perfusion is maintained.
Cardiac Intensive Care Unit, Great Ormond Street Hospital, London, UK.
K L
KL
Brown
A
A
Shefler
G
G
Cohen
C
C
DeMunter
N
N
Pigott
A P
AP
Goldman
D002303:Cardiac Output, Low / Q000209:etiology; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D007223:Infant; D008297:Male; D011015:Pneumonia, Aspiration / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome