[Accuracy of intraoperative diagnosis in central nervous system tumors: report of 1315 cases].
Clinicians order neurosurgery frozen sections in order to answer three questions: is the specimen tumor tissue? is it benign or malignant? what is its histological type? We studied the diagnostic accuracy of 1 315 frozen sections of central nervous system tumors, performed between 1988 and 1999, and compared it with data in the literature. Agreement between intraoperative and paraffin-section diagnosis was 96.6% (rate of error: 3.4% for the question tumor tissue or not). The answer was concordant in 92.6% with a 7.4% rate of error for tumor malignancy or benignity. Exact histological concordance was 87.6%. The most frequent errors in histological typing concerned gliomas, hemangioblastomas and metastasis. Our results emphazise the reliability of intraoperative frozen sections in Neurosurgery and the importance of close collaboration between clinicians, radiologists and pathologists.
Laboratoire d'Anatomie Pathologique, Hôpital des Spécialités Oto-Ophtalmologique, CHU Ibn Sina, Rabat, Maroc.
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Regragui
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Amarti Riffi
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Maher
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El Khamlichi
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Saidi
D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005910:Glioma / Q000473:pathology / Q000556:secondary / Q000601:surgery; D018325:Hemangioblastoma / Q000473:pathology / Q000556:secondary / Q000601:surgery; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies