Short communication: Net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver.
The objective was to determine whether net uptake of various nonesterified long chain fatty acids differs in the caprine liver. Caudate lobes were isolated from four mature goats and perfused (1 ml/min x g wet tissue) with buffer containing 0.3 mM of each palmitic, stearic, oleic, linoleic, linolenic, eicosapentaenoic, and docosahexaenoic acids. The amount of fatty acid in the perfusate decreased over time for all fatty acids with the exception of stearic acid. There was no net uptake of stearic acid, which was significantly different from all other fatty acids examined, with the exception of oleic acid. Net hepatic uptake of oleic acid was numerically, but not significantly lower than palmitic, linoleic, linolenic, eicosapentaenoic, and docosahexaenoic acids. It was concluded that net uptake of fatty acids was similar for all fatty acids tested with the exception of stearic acid.
Department of Dairy Science, University of Wisconsin, Madison 53706, USA.
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Mashek
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Grummer
D000818:Animals; D004281:Docosahexaenoic Acids / Q000378:metabolism; D015118:Eicosapentaenoic Acid / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D006041:Goats / Q000378:metabolism*; D007700:Kinetics; D019787:Linoleic Acid / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D019301:Oleic Acid / Q000378:metabolism; D019308:Palmitic Acid / Q000378:metabolism; D013229:Stearic Acids / Q000378:metabolism; D017962:alpha-Linolenic Acid / Q000378:metabolism
D005230:Fatty Acids, Nonesterified; D013229:Stearic Acids; D017962:alpha-Linolenic Acid; D004281:Docosahexaenoic Acids; D019301:Oleic Acid; D019308:Palmitic Acid; C031183:stearic acid; D019787:Linoleic Acid; D015118:Eicosapentaenoic Acid