Hormonal basis of mood and postpartum disorders.
Mood disorders during the postpartum period occur in 10% to 15% of women. The hormonal basis of these disorders, however, has not been investigated systematically and extensively. We review recent studies, primarily from the past 5 years, in which investigators examined the major categories of proposed hormonal etiologies, including gonadal steroids, thyroid hormones, cortisol, prolactin, and melatonin, and then present descriptive statistics of our preliminary findings in these hormonal dimensions from a group of 20 depressed and normal control pregnant and postpartum women.
Parry
Barbara L
BL
Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, USA. bparry@ucsd.edu
Sorenson
Diane L
DL
Meliska
Charles J
CJ
Basavaraj
Neal
N
Zirpoli
Gina G
GG
Gamst
Anthony
A
Hauger
Richard
R
D000328:Adult; D016022:Case-Control Studies; D019052:Depression, Postpartum / Q000097:blood* / Q000523:psychology; D004967:Estrogens / Q000097:blood; D005260:Female; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008550:Melatonin / Q000097:blood; D019964:Mood Disorders / Q000097:blood* / Q000209:etiology; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood; D013997:Time Factors
D004967:Estrogens; D006728:Hormones; D013963:Thyroid Hormones; D011374:Progesterone; D011388:Prolactin; D008550:Melatonin; D006854:Hydrocortisone