Utilisation of structurally diverse organophosphonates by Streptomycetes.
A group of streptomycete strains was found able to utilise a wide range of structurally diverse phosphonates as a sole phosphorus source. No relation could be observed between ability to synthesise compounds containing a direct carbon-to-phosphorus (C-P) bond and biodegradative potential towards phosphonates in the strains studied. Streptomyces morookaensis DSM 40565 could degrade 2-amino-4-phosphonobutyrate as a sole nitrogen and phosphorus source in a stereoselective-like manner. This result suggests the existence of a new metabolic pathway for C-P bond breakage.
Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland. obojska@kchf.ch.pwr.wroc.pl
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Obojska
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Lejczak
D000613:Aminobutyrates / Q000378:metabolism; D001426:Bacterial Proteins / Q000096:biosynthesis; D001673:Biodegradation, Environmental; D002458:Cell Fractionation; D009682:Magnetic Resonance Spectroscopy; D063065:Organophosphonates / Q000378:metabolism*; D013302:Streptomyces / Q000201:enzymology / Q000254:growth & development* / Q000378:metabolism*
D000613:Aminobutyrates; D001426:Bacterial Proteins; D063065:Organophosphonates; C012729:2-amino-4-phosphonobutyric acid