Cutaneous anthrax associated with facial palsy: case report and literature review.
BACKGROUND
Anthrax is primarily an animal disease. Bacillus anthracis, the causal agent in anthrax, is a Gram-positive rod. Humans can acquire anthrax by industrial exposure to infected animals or animal products.


METHODS
Reported here is the case of a 48-year-old male farm worker from Iran with a history of direct contact with herds. He presented after 6 days of fever with toxicity and a crusted ulcer on the face that was later confirmed bacteriologically to be cutaneous anthrax. He was treated with large doses of intravenous penicillin and corticosteroids along with multiple subcutaneous epinephrine injections that were used to control the infection and massive facial edema.


RESULTS
After 14 days, he partially recovered; however, ipsilateral facial nerve palsy developed and persisted despite therapeutic efforts.


CONCLUSIONS
It is not possible to conclude whether early diagnosis and treatment of anthrax results in a lower risk of complications. Facial palsy can be added to the list of variable complications of the cutaneous effects of anthrax.
Faghihi
G
G
Department of Dermatology, Isfahan University School of Medicine, Isfahan, Iran. g_faghihi@med.mui.ac.ir
Siadat
A H
AH
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000881:Anthrax / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D001408:Bacillus anthracis / Q000302:isolation & purification; D004837:Epinephrine / Q000008:administration & dosage; D005148:Facial Dermatoses / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005158:Facial Paralysis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000008:administration & dosage; D017192:Skin Diseases, Bacterial / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000305:Adrenal Cortex Hormones; D010406:Penicillins; D004837:Epinephrine