Hypertensive encephalopathy: antecedent to hippocampal sclerosis and temporal lobe epilepsy?
The authors describe three patients with refractory temporal lobe epilepsy (TLE) following an episode of hypertensive encephalopathy as their only identified antecedent event. All patients had typical MR features of hippocampal sclerosis (HS), and the two operated cases had typical HS histology and became seizure-free postoperatively. These cases suggest that hypertensive encephalopathy may be a rare form of initial precipitating injury, leading to TLE and HS.
Epilepsy Research Institute, University of Melbourne and Austin and Repatriation Medical Center, Melbourne, Victoria, Australia.
C
C
Solinas
R S
RS
Briellmann
A S
AS
Harvey
L A
LA
Mitchell
S F
SF
Berkovic
D038481:Anterior Temporal Lobectomy; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003952:Diagnostic Imaging; D017029:Epilepsy, Complex Partial / Q000209:etiology / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D005921:Glomerulonephritis / Q000150:complications; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications; D020343:Hypertensive Encephalopathy / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications; D009404:Nephrotic Syndrome / Q000150:complications; D012189:Retrospective Studies; D012598:Sclerosis / Q000209:etiology
D000959:Antihypertensive Agents