Effect of Indigofera aspalathoides against Dalton's ascitic lymphoma.
The effect of intraperitoneal injection of 400 mg/kg of ethanolic extract of Indigofera aspalathoides (EEIA) against Dalton's ascitic lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span, a decrease in the cancer cell count and body weight were noted in the tumour-induced mice after treatment with EEIA. These observations indicate that the plant is having protective effect in Dalton's ascitic lymphoma.
Christina
A J M
AJ
Division of Pharmacology, K M College of Pharmacy, Uthangudi, Melur Road, Madurai, Tamil Nadu, India. tinatina38@rediffmail.com
Alwin Jose
M
M
Heison Robert
S Jerry
SJ
Kothai
R
R
Chidambaranathan
N
N
Muthumani
P
P
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001201:Ascites / Q000188:drug therapy; D005472:Fluorouracil / Q000494:pharmacology; D029883:Indigofera; D007274:Injections, Intraperitoneal; D008223:Lymphoma / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D005472:Fluorouracil