GeneHopper: a web-based search engine to link gene-expression platforms through GenBank accession numbers.
Global gene-expression analysis is carried out using different technologies that are either array- or sequence-tag-based. To compare experiments that are performed on these different platforms, array probes and sequence tags need to be linked. An additional challenge is cross-referencing between species, to compare human profiles with those obtained in a mouse model, for example. We have developed the web-based search engine GeneHopper to link different expression resources based on UniGene clusters and HomoloGene orthologs databases of the National Center for Biotechnology Information (NCBI).
Center for Human and Clinical Genetics/Leiden Genome Technology Center, Leiden University Medical Center, The Netherlands.
B Anders T
BA
Svensson
Arja J
AJ
Kreeft
Gert-Jan B
GJ
van Ommen
Johan T
JT
den Dunnen
Judith M
JM
Boer
D000818:Animals; D019295:Computational Biology / Q000379:methods / Q000706:statistics & numerical data; D030561:Databases, Nucleic Acid / Q000706:statistics & numerical data*; D020869:Gene Expression Profiling / Q000706:statistics & numerical data*; D006801:Humans; D020407:Internet; D051379:Mice; D051381:Rats; D012984:Software