Indium-mediated reduction of hydroxylamines to amines.
[reaction: see text] A novel and simple procedure for reduction of hydroxylamines to the corresponding amines by means of indium powder in aqueous media is reported. Applicability to one-pot reactions and isoxazolidine N-O bond reduction is also demonstrated. A catalytic version of the process using 2-5% In in the presence of other metals (Zn, Al) has been successfully developed.
Dipartimento di Chimica Organica Ugo Schiff, Università di Firenze, via della Lastruccia 13, I-50019 Sesto Fiorentino (FI), Italy.
Stefano
S
Cicchi
Marco
M
Bonanni
Francesca
F
Cardona
Julia
J
Revuelta
Andrea
A
Goti