(+/-)-5-(4-methoxyphenylaminocarbonyl)-1-azabicyclo[3.3.0]octan-2-one benzene solvate.
The title trans prolyl amide exists as a benzene solvate, C(15)H(18)N(2)O(3).C(6)H(6), with positional disorder of the prolyl ring. The molecular structure is influenced by a close intramolecular N-H...N contact that provides structural support for the intramolecular catalysis of peptidyl-prolyl cis-trans isomerization.
Wheeler
Kraig A
KA
Department of Chemistry, Delaware State University, Dover, DE 19901, USA. kwheeler@dsc.edu