The role of the counteranion in the cation-pi interaction.
Chemical double mutant cycles have been used to quantify cation-pi interactions in chloroform as a function of the nature of the counteranion. The cation-pi interaction is -2.5 +/- 0.4 kJ mol(-1) and independent of the anion, even though the overall stability of the complexes varies by an order of magnitude due to competition of the anion for alternative binding sites.
Hunter
Christopher A
CA
Centre for Chemical Biology, Krebs Institute for Biomolecular Science, Department of Chemistry, University of Sheffield, Sheffield, UK S3 7HF. C.Hunter@Sheffield.ac.uk
Low
Caroline M R
CM
Rotger
Carmen
C
Vinter
Jeremy G
JG
Zonta
Cristiano
C