Effects of oral contraceptives on total serum proteins, albumin, globulins and cholesterol levels in Ibadan, Nigeria.
Total serum protein, albumin, globulin, albumin/globulin ratio and cholesterol levels were determined in 25 subjects on oral contraceptives and 25 controls. The mean serum total protein, globulin and cholesterol levels were significantly increased in oral contraceptive and their control counterparts. The albumin/globulin ratio in subjects on oral contraceptives users is significantly decreased compared with controls. In view of the findings of this study, it is suggested that the biochemical profile of long-term oral contraceptive users be assessed periodically.
Obisesan
K A
KA
Department of Obstetrics and Gynaecology, College of Medicine University of Ibadan, Nigeria.
Adenaike
F A
FA
Okunlola
M A
MA
Adenaike
A A
AA
D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000187:drug effects*; D002784:Cholesterol / Q000097:blood*; D003276:Contraceptives, Oral / Q000009:adverse effects*; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000139:chemically induced*; D009549:Nigeria; D012709:Serum Albumin / Q000187:drug effects*; D012712:Serum Globulins / Q000187:drug effects*; D013997:Time Factors
D001798:Blood Proteins; D003276:Contraceptives, Oral; D012709:Serum Albumin; D012712:Serum Globulins; D002784:Cholesterol