A combined approach of enamel matrix derivative gel and autogenous bone grafts in treatment of intrabony periodontal defects. A case report.
Enamel matrix derivative (EMD) has recently been introduced as a new modality in regenerative periodontal therapy. This case report demonstrates a combined approach in topical application of EMD gel (Emdogain) and autogenous bone grafts for treatment of intrabony defects and furcation involvement defects in a patient with chronic periodontitis. The seven-month post-surgery clinical and radiographic results were presented. The combined application of EMD gel with autogenous bone grafts in intrabony osseous defects resulted in clinically significant gain of attachment on diseased root surfaces and bone fill on radiographs. Further controlled clinical studies are required to confirm the long-term effectiveness of the combination of EMD gel and autogenous bone grafts in treatment of various osseous defects in subjects with chronic periodontitis.
Leung
George
G
Faculty of Dentistry, Periodontology, University of Hong Kong, Hong Kong, PR China.
Jin
Lijian
L
D016301:Alveolar Bone Loss / Q000601:surgery*; D001861:Bone Regeneration / Q000502:physiology; D016025:Bone Transplantation; D002908:Chronic Disease; D003746:Dental Enamel Proteins / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D017823:Furcation Defects / Q000601:surgery; D005782:Gels; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000601:surgery; D010518:Periodontitis / Q000601:surgery; D014182:Transplantation, Autologous
D003746:Dental Enamel Proteins; D005782:Gels; C109069:enamel matrix proteins