Altering T-cell activation by targeting the multidomain tyrosine kinase Itk.
Kanner
Steven B
SB
Immunology and Oncology Drug Discovery, Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ 08543, USA.
Perez-Villar
Juan J
JJ
D000818:Animals; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology*; D011505:Protein-Tyrosine Kinases / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D011505:Protein-Tyrosine Kinases; C080813:emt protein-tyrosine kinase