Apparent eradication of Mycoplasma synoviae in broiler breeders subjected to intensive antibiotic treatment directed to control Escherichia coli.
A Mycoplasma synoviae (MS)-free flock of broiler breeders was housed for brooding and rearing on an MS endemic farm. PCR revealed that the flock became infected within nine weeks. At 22 weeks the flock was transferred to a clean and disinfected house on a previously depopulated farm. The birds were then subjected to three treatments with fluoroquinolones due to recurrent Escherichia coli peritonitis and from the 32 weeks of age they received 600 ppm of oxytetracycline hydrochloride continuously in the feed. Monitoring by PCR showed a decrease in MS positive birds after 34 weeks of age and MS may have been eradicated as judged by consistent negative results in PCR. We conclude that intensive antibiotic treatments supported by adequate biosecurity could clear MS from infected broiler breeders.
Fiorentin
Laurimar
L
Brazilian Agricultural Research Corporation--EMBRAPA Embrapa Suínos e Aves, BR 153, km 110, Vila Tamanduá, Caixa Postal 21, 89700-000, Concórdia, SC, Brazil. laurimar@cnpsa.embrapa.br
Soncini
Ricardo A
RA
da Costa
José Luiz A
JL
Mores
Marcos A Z
MA
Trevisol
Iara M
IM
Toda
Márcia
M
Vieira
Nilson D
ND
D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001938:Brazil / Q000453:epidemiology; D002645:Chickens; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D005260:Female; D024841:Fluoroquinolones; D006920:Hygiene; D008297:Male; D009174:Mycoplasma / Q000187:drug effects / Q000302:isolation & purification; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D010118:Oxytetracycline / Q000627:therapeutic use; D010538:Peritonitis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary; D016133:Polymerase Chain Reaction / Q000379:methods / Q000662:veterinary; D011201:Poultry Diseases / Q000188:drug therapy / Q000453:epidemiology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D010118:Oxytetracycline