Herbicidal, plant growth inhibitory, and cytotoxic activities of bismuthines containing aromatic heterocycles.
This work presents the herbicidal and plant growth regulatory activities of tertiary bismuthines containing heterocyclic aromatic rings of the general formula (2-C(4)H(3)X)(3)Bi, where X = S (3), O (1), or NMe (2). Toxicity against Artemia salina and herbicidal activity on Lactuca sativa, Trifolium pratense, and Lolium multiflorum were tested. In addition to the effects on mitochondrial respiration obtained from roots of Phaseolus vulgaris, these compounds also demonstrated partial radical scavenging properties against 2,2-diphenyl-1-picrylhydrazyl (DPPH). The furyl substituent is the most important structural requirement for the activity measurements observed in this study.
Instituto de Química, Universidad Nacional Autónoma de México, Coyoacán 04510, Mexico D.F., Mexico. ccespede@servidor.unam.mx
Carlos L
CL
Céspedes
Adela
A
Lemus
Juan R
JR
Salazar
Armando
A
Cabrera
Pankaj
P
Sharma
D000818:Animals; D001156:Artemia / Q000187:drug effects; D001713:Biphenyl Compounds; D001729:Bismuth / Q000032:analysis*; D016166:Free Radical Scavengers / Q000494:pharmacology; D006540:Herbicides / Q000494:pharmacology*; D006571:Heterocyclic Compounds / Q000737:chemistry* / Q000494:pharmacology*; D018545:Lactuca / Q000187:drug effects / Q000254:growth & development; D008129:Lolium / Q000187:drug effects / Q000254:growth & development; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D010101:Oxygen Consumption / Q000187:drug effects; D027805:Phaseolus / Q000648:ultrastructure; D010851:Picrates; D010937:Plant Growth Regulators / Q000494:pharmacology*; D018517:Plant Roots / Q000648:ultrastructure; D012639:Seeds / Q000187:drug effects; D029921:Trifolium / Q000187:drug effects / Q000254:growth & development
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006540:Herbicides; D006571:Heterocyclic Compounds; D010851:Picrates; D010937:Plant Growth Regulators; C004931:1,1-diphenyl-2-picrylhydrazyl; D001729:Bismuth