Microelectrode array on folding polyimide ribbon for epidural mapping of functional evoked potentials.
This paper describes a flexible polyimide microelectrode ribbon with a bending structure for epidural recording. Bending the ribbon establishes good electro-mechanical contact of the electrodes to the cortex. Impedance spectroscopy and noise measurements in vitro were used to characterize the electrodes. Our in vivo experiments then successfully achieved synchronized neuronal activity and evoked potential patterns useful for understanding brain function and for finding cortical function.
Department of Engineering Synthesis, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. hiro@hnl.t.u-tokyo.ac.jp
Hirokazu
H
Takahashi
Takayuki
T
Ejiri
Masayuki
M
Nakao
Naoya
N
Nakamura
Kimitaka
K
Kaga
Thierry
T
Hervé
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001672:Biocompatible Materials; D001931:Brain Mapping / Q000295:instrumentation*; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation; D004824:Epidural Space / Q000502:physiology; D004867:Equipment Design; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D008839:Microelectrodes; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012117:Resins, Synthetic
D001672:Biocompatible Materials; D012117:Resins, Synthetic; C029945:polyimide resin