[A rare massive parenchymal metastasis in central nervous system from abdominal non-Hodgkin lymphoma: effectiveness of stereotactic radiosurgey: case report].
A 62-year-old female presented with a rare massive parenchymatous metastasis from abdominal malignant lymphoma. Computed tomography and magnetic resonance image revealed a large enhanced mass in the right basal ganglia. 123I-IMP SPECT showed increased uptake on both early and delayed images. A stereotactic biopsy was performed; histological examination revealed a diffuse large B-cell malignant lymphoma. The patient underwent stereotactic radiosurgery (SRS). Short-term cliniconeuroradiological follow-up showed both neurologic improvement and virtually complete disappearance of the tumor. Our findings suggest that 123I-IMP SPECT can help differentiate malignant lymphoma from benign lesions and other malignant brain tumors. In addition, SRS with conventional radiotherapy may be an effective therapeutic strategy to control malignant lymphoma.
Uchino
Masafumi
M
Department of Neurosurgery, Toho University School of Medicine, 6-11-1 Ohmori-Nishi, Ota-ku, Tokyo 143-8541, Japan.
Kitajima
Satoru
S
Yokota
Kyosuke
K
Nagao
Takeki
T
Seiki
Yoshikatsu
Y
Shibata
Iekado
I
Natori
Kazuhiko
K
Hasegawa
Chikako
C
D000008:Abdominal Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008875:Middle Aged; D016634:Radiosurgery / Q000379:methods