[Relationship between plasminogen activator, plasminogen activator inhibitor and Sertoli cells].
Plasminogen activator(PA) and plasminogen activator inhibitor(PAI) are involved in many physiological or pathological events. The Sertoli cells, the important elements within the seminiferous epithelium, are thought to play a key role in spermatogenesis. The Sertoli cells secrete PA and PAI. The levels of them are modulated by hormonal and cell-mediated influences. They play a fundamental role in the maintenance of spermatogenesis, sperm motility and fertilization.
Wang
Xiao-Yan
XY
Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Xiong
Cheng-Liang
CL
D006801:Humans; D008297:Male; D010960:Plasminogen Activators / Q000378:metabolism* / Q000502:physiology; D015849:Plasminogen Inactivators / Q000378:metabolism* / Q000502:physiology; D012708:Sertoli Cells / Q000378:metabolism* / Q000502:physiology; D013737:Testis / Q000166:cytology
D015849:Plasminogen Inactivators; D010960:Plasminogen Activators