Occurrence of the spinal reflex due to skin pressure in sudomotor and cutaneous vasoconstrictor nerve system of humans.
The effects of skin pressure applied to one side of the waist on sudomotor and vasoconstrictor nerve activity were compared with the effects on sweating and cutaneous blood flow in humans. The sweat rate and cutaneous blood flow were measured on left and right dorsal feet. Skin sympathetic nerve activity (SSNA) was recorded by microneurography from a microelectrode inserted in left and right peroneal nerves. Skin pressure was applied in a supine position to the area over the left or right anterior superior iliac spine under warm (T(a): 30-36 degrees C) and cool (T(a): 19-23 degrees C) conditions. Sudomotor and vasoconstrictor bursts were identified for quantitative analysis. The skin pressure increased the contralateral/ipsilateral ratio of the sweat rate. It also increased the contralateral/ipsilateral ratio of the cutaneous blood flow and the contralateral/ipsilateral ratio of the sudomotor burst amplitude. However, skin pressure did not induce any significant changes in the contralateral/ipsilateral ratio of the vasoconstrictor burst amplitude. The results indicate that an asymmetrical reflex effect of skin pressure on vasoconstrictor nerve activity was absent, suggesting that, whereas the ipsilateral suppression of sweating elicited by skin pressure was mediated by the sudomotor nerve system, the ipsilateral suppression of cutaneous blood flow was not mediated by the vasoconstrictor nerve system. Thus, the occurrence of the spinal reflex due to skin pressure is not uniform between the sudomotor and the vasoconstrictor nerve systems, which represent different organizations at the level of spinal cord.
Department of Physiology, School of Medicine, Aichi Medical University, Nagakute, Aichi 480-1195, Japan.
Tomoko
T
Okagawa
Junichi
J
Sugenoya
Satoshi
S
Iwase
Tadaaki
T
Mano
Akio
A
Suzumura
Takaaki
T
Matsumoto
Yoshiki
Y
Sugiyama
D000328:Adult; D003080:Cold Temperature; D006358:Hot Temperature; D006801:Humans; D008297:Male; D010543:Peroneal Nerve / Q000502:physiology*; D011312:Pressure; D012018:Reflex / Q000502:physiology*; D012867:Skin / Q000098:blood supply*; D012881:Skin Temperature / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*; D013546:Sweating / Q000502:physiology; D014661:Vasoconstriction / Q000502:physiology*