Secretion: kiss and run caught on film.
Recent results have provided graphic support for the hypothesis that vesicle secretion involves a 'kiss-and-run' mechanism. Evanescent field microscopy has shown that, during exocytosis, intravesicular markers escape without collapse of the vesicular membrane into the surface membrane and that the empty vesicle is immediately retrieved back into the cell.
Department of Neurobiology, Pharmacology and Physiology, University of Chicago, Illinois 60637, USA.
H Clive
HC
Palfrey
Cristina R
CR
Artalejo
D000818:Animals; D005089:Exocytosis / Q000502:physiology*; D007425:Intracellular Membranes / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008853:Microscopy / Q000379:methods; D022142:Secretory Vesicles / Q000378:metabolism*
D008565:Membrane Proteins