First human case of nocardiosis caused by Nocardia pseudobrasiliensis in Japan.
Nocardia sp. IFM 0896, an actinomycete with biochemical characteristics that differed from Nocardia brasiliensis, was isolated from a 71-year-old Japanese man with a history of tuberculosis and cancer. Although the isolate was tentatively identified as N. brasiliensis, the morphological and physiological characteristics of strain IFM 0896 were different from those of N. brasiliensis IFM 0236T. The results of 16S rRNA gene sequence phylogenies and PCR-RFLP analysis of a heat shock protein revealed that Nocardia sp. IFM 0896 belongs to the species N. pseudobrasiliensis. This is the first clinical isolation report of N. pseudobrasiliensis in Japan.
Kageyama
Akiko
A
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8673, Japan.
Sato
Hiroko
H
Nagata
Matsuo
M
Yazawa
Katsukiyo
K
Katsu
Masakazu
M
Mikami
Yuzuru
Y
Kamei
Katsuhiko
K
Nishimura
Kazuko
K
D000368:Aged; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D007564:Japan; D008297:Male; D009615:Nocardia / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D009617:Nocardia Infections / Q000382:microbiology* / Q000473:pathology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012336:RNA, Ribosomal, 16S / Q000737:chemistry / Q000235:genetics; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S