Antioxidant flavonoids and phenolic acids from leaves of Leea guineense G Don (Leeaceae).
From leaves of Leea guineense (Leeaceae) three hydrophilic flavonoids were isolated and identified as quercetin-3'-sulphate-3-O-alpha-L-rhamnopyranoside, quercetin-3,3'-disulphate and a new flavonoid sulphate, quercetin-3,3',4'-trisulphate, together with kaempferol, quercetin, quercitrin, mearnsitrin, gallic acid and ethyl gallate. The structures were established by spectroscopic analysis (UV, MS, (1)H-NMR, (13)C-NMR and 2D-NMR). Their antioxidant effect on free radical scavenging was evaluated in the DPPH assay.
Département de Pharmacochimie Moléculaire UMR 5063 CNRS/UJF, Faculté de Pharmacie de Grenoble, LA TRONCHE, France.
Philippe
P
Op de Beck
Gilbert
G
Cartier
Bruno
B
David
Marie-Geneviève
MG
Dijoux-Franca
Anne-Marie
AM
Mariotte
D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001713:Biphenyl Compounds; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D062385:Hydroxybenzoates / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010851:Picrates; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D027844:Vitaceae
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D062385:Hydroxybenzoates; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl; C017616:phenolic acid