Gonadotropins and sex hormones modulate interrenal function in soft-shelled turtle.
The aim of the current work was to investigate the role of gonadotropins and female sex hormones on interrenal activity in soft-shelled turtles, Lissemys punctata punctata. 1) FSH treatment (3 microg/100 g body wt daily for 10 days) caused interrenal hypertrophy with increased nuclear diameter, raises of acid phosphatase and alkaline phosphatase concentrations, and depletions of cholesterol (except the free fraction) and ascorbic acid levels from the interrenal gland. However, LH treatment (3 microg/100 g body wt daily for 10 days) failed to produce any perceptible change in the interrenal activity. The combined treatments of FSH and LH (3 microg each/100 gm body wt daily for 10 days) produced no further change beyond that of FSH alone. 2) Estrogen treatment with the low dose (25 microg/100 g body wt daily for 10 days) had no effect, but with higher doses (50 microg or 100 microg/100 gm body wt daily for 10 days) is caused interrenal stimulation by inducing the same manifestations to those of FSH. The degree of manifestations was higher with the higher dose (100 microg daily) than that of the moderate dose (50 microg daily). Progesterone treatment with the low dose (25 microg /100 g body wt daily for 10 days) had no significant effect, but with the moderate (50 microg daily) and higher (100 microg daily) doses suppressed interrenal activity by showing the reverse changes to those of estrogen. The degree of manifestations was higher with the higher dose than that of the moderate one. The combined treatments of estrogen and progesterone (100 microg each/100 g body wt daily for 10 days) caused interrenal stimulation but to a lesser extent than that of estrogen alone. The findings are briefly discussed.
Ray
Prajna P
PP
Histophysiology Laboratory, Department of Zoology, University of Calcutta (Ballygunge Campus), 35 Ballygunge Circular Road, Calcutta 700 019, India.
Maiti
B R
BR
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D012739:Gonadal Steroid Hormones / Q000494:pharmacology*; D007401:Interrenal Gland / Q000187:drug effects* / Q000502:physiology; D007986:Luteinizing Hormone / Q000494:pharmacology*; D011374:Progesterone / Q000494:pharmacology; D014426:Turtles / Q000033:anatomy & histology / Q000097:blood / Q000502:physiology*
D004967:Estrogens; D012739:Gonadal Steroid Hormones; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone