[Risk factors for gestational trophoblastic tumors following complete hydatidiform mole].
OBJECTIVE
The aim of our study was to determine the factors associated with higher incidence of trophoblastic tumours following complete hydatidiform mole.


METHODS
Epidemiological and clinical factors were studied in eighty five patients with complete hydatidiform mole evacuated from 1973 to 1997 in Department of Obstetrics and Gynecology Medical University of Gdańsk. Univariate and multivariate analysis were used to study of group.


CONCLUSIONS
In the analysis of 85 patients we found three prognostically independent factors that were associated with higher incidence of trophoblastic tumours after the complete hydatidiform mole: pre-evacuation hCG level, presence of prominent theca lutein cysts (greater than 6 cm in diameter) and molar pregnancy in the patient's past history. Persistent vomiting was a symptom of lower significance as a risk factor of trophoblastic tumour.
Grzybowski
Wojciech
W
Kliniki Połoznictwa Instytutu Połoznictwa i Chorób Kobiecych, Akademii Medycznej w Gdańsku.
Płoszyński
Andrzej
A
Mielnik
Jerzy
J
Adamcio-Deptulska
Maria
M
Preis
Krzysztof
K
Wojciechowska
Danuta
D
D000328:Adult; D002471:Cell Transformation, Neoplastic; D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000737:chemistry / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006828:Hydatidiform Mole / Q000737:chemistry / Q000473:pathology*; D015994:Incidence; D008184:Luteal Cells; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000737:chemistry / Q000473:pathology*
D006063:Chorionic Gonadotropin