Analytical procedure for the simultaneous voltammetric determination of toxic metals in dialysis fluids.
A new analytical voltammetric procedure for the simultaneous determination of copper(II), lead(II), cadmium(II), zinc(II), chromium(VI), and manganese(II) in two kinds of dialysis fluid (peritoneal and haemodialysis fluids) is described. The voltammetric measurements were performed using, as working electrode, a stationary mercury electrode, and a platinum electrode and a Agmid R:AgClmid R:KCl ((sat.)) electrode as auxiliary and reference electrodes, respectively, employing 0.1 mol L(-1) dibasic ammonium citrate solution pH 6.9 as supporting electrolyte. For all the elements, the accuracy, expressed as relative recovery R%, was very satisfactory being in the range 94-105%, the precision, expressed as relative standard deviation s(r)%, was lower than 6%, while the limits of detection were of the order of a few units of microg L(-1). The analytical voltammetric procedure has been validated by comparison with spectroscopic (graphite furnace atomic absorption spectroscopy, GFAAS) measurements.
Department of Chemistry G. Ciamician, University of Bologna, Via F. Selmi 2, 40126, Bologna, Italy. clinio@ciam.unibo.it
Clinio
C
Locatelli
D002138:Calibration; D015314:Dialysis Solutions / Q000032:analysis*; D004563:Electrochemistry; D007202:Indicators and Reagents; D019216:Metals, Heavy / Q000032:analysis*; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013054:Spectrophotometry, Atomic
D015314:Dialysis Solutions; D007202:Indicators and Reagents; D019216:Metals, Heavy