[Inhibition of human gastric carcinoma cell growth by vitamin E succinate].
The effects of vitamin E succinate (VES) on the growth of human gastric carcinoma cell (SGC-7901) were examined and compared with the effects of alpha-tocopherol by MTT assay. It was found that VES(5, 10 and 20 micrograms/ml) inhibited cell growth significantly, but alpha-tocopherol did not show any inhibition effects. The results showed that the anticancer effect of VES and the anticancer mechanism of VES is different from alpha-tocopherol.
Public Health School of Harbin Medical University, Harbin 150001, China.
B
B
Liu
K
K
Wu
D
D
Zhao
D000230:Adenocarcinoma / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D013274:Stomach Neoplasms / Q000473:pathology*; D024505:Tocopherols; D014407:Tumor Cells, Cultured; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000494:pharmacology*; D024502:alpha-Tocopherol / Q000494:pharmacology
D014810:Vitamin E; D024502:alpha-Tocopherol; D024505:Tocopherols