A prospective study to evaluate the efficacy of two- and three-dimensional sonohysterography in women with intrauterine lesions.
OBJECTIVE
To measure the accuracy of three-dimensional (3D) sonohysterography in detecting intrauterine lesions.


METHODS
Prospective study.


METHODS
Teaching hospital.


METHODS
Two hundred nine infertile patients suspected to have an intrauterine lesion on 2D ultrasound or hysterosalpingography.


METHODS
Three-dimensional ultrasound, 2D and 3D sonohysterography (SHG). Ninety-two of the patients had a lesion distorting the endometrium on the 3D SHG, and those were referred for hysteroscopy.


METHODS
Sensitivity and specificity of 2D, 3D ultrasound, and 2D SHG compared to 3D SHG.


RESULTS
Of the 92 patients with a lesion, 48 had polyps, 35 submucous/intramural myomas, 3 both polyps and myomas, 4 müllerian anomalies, 1 thick endometrium, and 1 synechiae. Compared with the 3D SHG results, the sensitivity and specificity were 97% and 11% for the 2D transvaginal ultrasound, 87% and 45% for the 3D ultrasound, and 98% and 100% for the 2D SHG. In the group of 59 patients who had hysteroscopy, the sensitivity of the 2D SHG and 3D SHG were 98% and 100%, with a positive predictive value of 95% and 92%, respectively.


CONCLUSIONS
Three-dimensional sonohysterography allows precise recognition and localization of lesions. If 2D and 3D SHG are normal, invasive diagnostic procedures such as hysteroscopy could be avoided.
Sylvestre
Camille
C
McGill Reproductive Center, Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montréal, Québec, Canada. camsylvestre@hotmail.com
Child
Tim J
TJ
Tulandi
Togas
T
Tan
Seang Lin
SL
D000328:Adult; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007889:Leiomyoma / Q000000981:diagnostic imaging*; D011127:Polyps / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging*; D014599:Uterus / Q000000981:diagnostic imaging*