Identification of the L-aspartate transporter in Bacillus subtilis.
YveA of Bacillus subtilis, a putative transporter of the amino acid/polyamine/organocation (APC) superfamily, is shown to mediate uptake of both L-aspartate and L-glutamate as well as having sensitivity to L-aspartate hydroxamate. This 14 TMS protein is the primary aspartate uptake system in B. subtilis and serves as the prototype for a new family within the APC superfamily.
Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093-0116, USA.
Graciela
G
Lorca
Brit
B
Winnen
Milton H
MH
Saier
D026922:Amino Acid Transport Systems, Acidic / Q000235:genetics* / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D001216:Asparagine / Q000031:analogs & derivatives* / Q000494:pharmacology; D001224:Aspartic Acid / Q000378:metabolism*; D001412:Bacillus subtilis / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D002455:Cell Division / Q000502:physiology; D003001:Cloning, Molecular; D018698:Glutamic Acid / Q000378:metabolism; D009154:Mutation; D010802:Phylogeny; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D013379:Substrate Specificity
D026922:Amino Acid Transport Systems, Acidic; D000596:Amino Acids; D001426:Bacterial Proteins; D002352:Carrier Proteins; D011993:Recombinant Fusion Proteins; C474649:YveA protein, Bacillus subtilis; C024848:beta-aspartylhydroxamic acid; D001224:Aspartic Acid; D018698:Glutamic Acid; D001216:Asparagine