Langerhans cell histiocytosis presenting as adult onset epilepsy.
A 37 year old man presented with recurrent secondarily generalized seizures from right partial onset since December 1999, MRI scan of brain (contrast study) revealed multiple enhancing lesions predominantly involving frontal, parietal and temporal regions. Left frontotemporal lesion was biopsied and histopathology confirmed it to be rare case of adult Langerhans cell histiocytosis. He was given short course of oral corticosteroids. Two years postoperative course on antiepileptic therapy alone is uneventful and repeat MRI brain and MR spectroscopy showed significant resolution of lesions.
Jain
R S
RS
Dept. of Neurology, RNT Medical College, Udaipur, India.
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007194:India; D008279:Magnetic Resonance Imaging; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
D000927:Anticonvulsants; D005938:Glucocorticoids; D002220:Carbamazepine; D011239:Prednisolone