Vancomycin-associated linear IgA bullous dermatosis mimicking toxic epidermal necrolysis.
Vancomycin is the most frequent trigger of drug-induced linear IgA bullous dermatosis. We describe a fulminant case of linear IgA bullous dermatosis in a 74-year-old man who experienced skin sloughing of 90% of his body surface after receiving vancomycin.
Department of Dermatology, University of Colorado School of Medicine, Denver, 90262, USA.
Robert P
RP
Dellavalle
Joanna M
JM
Burch
Shalini
S
Tayal
Loren E
LE
Golitz
James E
JE
Fitzpatrick
Patrick
P
Walsh
D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis; D013203:Staphylococcal Infections / Q000188:drug therapy; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis*; D014640:Vancomycin / Q000009:adverse effects* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D007070:Immunoglobulin A; D014640:Vancomycin