[Results of cervical cancer treatment at the Lower Silesian Oncology Center between 1987 and 1989].
OBJECTIVE
The aim of the project was to analyze a survival of patients with cervical cancer during 10-years follow-up and to identify factors that predict survival. Age, place of living (city vs. country), stage of disease, histology of the tumor and performed treatment were considered as potential prognostic factors.


METHODS
The analysis included 497 patients diagnosed with cervical cancer, treated in Lower Silesian Oncology Centre between 1987 and 1989. Squamous cell carcinoma was a predominant type of the tumors. 488 patients were treated with radiotherapy, 92 patients underwent hysterectomy m. Freund. Intracavitary brachytherapy with radium 226 or cesium 137 (remote after loading--technique) was performed in most (486) patients.


RESULTS
10-years survival rate was 43.5% (216 patients), 5-years-survival 53.3%. During 5-year follow-up mortality decreased more rapidly than during next 5 years. It has been observed, that prognosis was better for younger patients (< 50 years old) with 10-y SR (survival rate) of 51.9%, compared with the group of older (> 50 years old) with 10-y SR of 35.5%. No difference in survival was noticed between patents living in the cities and in the country. Like other, I found that clinical stage of disease is the most important prognostic factor based on observed SR. 5-y SR was 72.5%, 59.5%, 22.1% an 10-y SR was 63.8%, 48%, 15.2% for stage Ib, IIb, IIIb respectively. Brachytherapy with cesium resulted in improved SR of 50.9% compared with radium (39.8%).


CONCLUSIONS
Based on obtained data, the factors of prognostic value are: stage of disease, age and treatment.
Katedry Onkologii i Kliniki Ginekologii Onkologicznej Akademii Medycznej we Wrocławiu.
Jacek
J
Dryl
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008197:Lymph Node Excision; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D012074:Remission Induction; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000628:therapy*