Improved detection of inferobasal ischemia during dobutamine echocardiography with doppler tissue imaging.
OBJECTIVE
The purpose of this study was quantitative evaluation of the inferobasal segment during dobutamine stress echocardiography using Doppler tissue imaging (DTI).


BACKGROUND
Overdiagnosis of myocardial ischemia during dobutamine echocardiography is a common problem. DTI may permit more accurate quantitative diagnosis of ischemia.


METHODS
A total of 50 patients with normal contraction of the inferobasal segment at rest were referred for dobutamine stress echocardiography. All underwent coronary angiography. Systolic and diastolic myocardial velocities were measured from apical 2-chamber view at rest and at the peak of dobutamine infusion.


RESULTS
Stenosis of the right coronary artery >or= 70% was detected in 11 patients. Conventional stress echocardiography was falsely positive in 10.3% and falsely negative in 27.3%. When DTI was combined with conventional stress echocardiography, sensitivity and specificity was 81.8% and 97.4%, respectively.


CONCLUSIONS
DTI may enhance the diagnosis of inferior ischemia during dobutamine echocardiography and can be added to conventional imaging in the treatment of these patients.
Leitman
Marina
M
Cardiology Department, Assaf Harofeh Medical Center, Zerifin, Israel. zvered@asaf.health.gov.il
Sidenko
Stanislav
S
Wolf
Ruth
R
Sucher
Edgar
E
Rosenblatt
Simha
S
Peleg
Eli
E
Krakover
Ricardo
R
Vered
Zvi
Z
D000328:Adult; D000368:Aged; D025401:Echocardiography, Stress; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity