[Clinical study of sarcomatoid renal cell carcinoma].
Patients with sarcomatoid renal cell carcinoma are rare and have poor survival. We evaluated 14 patients who had renal cell carcinoma with a sarcomatoid component between 1982 and 2000. There were 9 men and 5 women with a median age of 59.5 years (range 32 to 77). Seven patients had a tumor on the right side and 7 on the left side. Thirteen patients had some symptoms and 11 had metastases at the initial visit. Most of them were stage T4 and high nuclear grade cancer and showed elevated acute phase reactants. There were 7 patients followed by interferon therapy, and the cause-specific 5-year survival rate was less than 10%. We confirmed that renal cell carcinoma with a sarcomatoid component often showed local invasion, distant metastasis and poor prognosis.
Ohba
Kojiro
K
Department of Urology, Nagasaki University Graduate School of Biochemical Science.
Koga
Shigehiko
S
Nishikido
Masaharu
M
Miyata
Yasuyoshi
Y
Noguchi
Mitsuru
M
Kanetake
Hiroshi
H
Kanda
Shigeru
S
Hayashi
Tomayoshi
T
Yamada
Jun
J
D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012509:Sarcoma / Q000401:mortality / Q000473:pathology*; D015996:Survival Rate