Endovascular cooling with heat exchange catheters: a new method to induce and maintain hypothermia.
OBJECTIVE
To test the convenience of a new cooling technique with intravenous heat exchange catheters.


METHODS
Retrospective chart review.


METHODS
University hospital neurointensive care unit.


METHODS
Twenty patients with severe subarachnoid hemorrhage Hunt and Hess Grade 3-5 treated with mild hypothermia.


METHODS
Cooling to reach target body core temperature (33 degrees C-34 degrees C) was induced as quickly as possible in all patients. In the first ten patients (group one) moderate hypothermia was induced and maintained using cooling blankets. In group two, an 8.5F heat exchange catheter was placed central venous and temperature-adjusted normal saline circulated in a closed-loop system entailing two balloons.


RESULTS
A total of 2,007 values of body core temperature (BCT) were registered every hour. Foley temperature catheters were used for monitoring BCT in the bladder. The time to reach the target BCT and the stability of temperature during hypothermia were compared between the two groups. No specific complications associated with the new cooling device were observed. Time to reach the target temperature in group two was significantly shorter than in group one (190+/-110 and 370+/-220 min) ( P=0.023). In group one significantly more temperature values were out of the target range (127 of 792 values; 16.0%) than in group two (62 of 1,215 values; 5.1%) ( P<0.0001).


CONCLUSIONS
The new endovascular cooling technique seems to be superior for rapid induction of hypothermia and maintaining a more stable temperature than the cooling techniques using blankets and ice bags.
Keller
Emanuela
E
Department of Neurosurgery, Nordtrakt 1, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland. ees@usc.ch.
Imhof
Hans-Georg
HG
Department of Neurosurgery, Nordtrakt 1, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Gasser
Stefan
S
Department of Neurosurgery, Nordtrakt 1, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Terzic
Andre
A
Department of Neurosurgery, Nordtrakt 1, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Yonekawa
Yasuhiro
Y
Department of Neurosurgery, Nordtrakt 1, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
D001831:Body Temperature; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002408:Catheters, Indwelling; D016292:Procedural Sedation / Q000379:methods; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016037:Single-Blind Method; D013345:Subarachnoid Hemorrhage / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome