[Soft tissue myoepithelioma, a rare tumor. A case report].
Myoepithelioma of soft tissues is a rare and under-recognized tumor. We report a case of a myoepithelioma arising in the soft tissue of the wrist in a 37-year-old man. This 3cm, nodular, well circumscribed tumor consisted of a mixture of spindle and epithelioid cells in a fibrous or focally myxoid stroma. Nuclear atypia were mild and mitotic activity was 1 mitotic figure per 10 high-power fields. No tubular epithelial structure was found. The tumoral cells expressed cytokeratin (KL1) and S-100 protein. Smooth muscle actin and desmin were negative. The excision was complete. At 5 months, no recurrence was noted. Myoepithelioma of deep soft tissue has a predilection for extremity involvement. It has to be differentiated from extraskeletal myxoid chondrosarcoma, parachordoma and synovial sarcoma. Most of myoepitheliomas are benign. However, metastasis may occur in a minority of cases.
Service d'anatomie et cytologie pathologiques, Centre Hospitalier Général, 1 avenue Michel de l'Hospital, 02321 Saint-Quentin.
Magali
M
Colombat
Agnès
A
Lesourd
Mirdad
M
Moughabghab
Jean-Michel
JM
Coindre
Sophie
S
Carton
D000199:Actins / Q000032:analysis; D000328:Adult; D002467:Cell Nucleus / Q000473:pathology; D003893:Desmin / Q000032:analysis; D004847:Epithelial Cells / Q000473:pathology; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D008938:Mitosis; D009208:Myoepithelioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
D000199:Actins; D003893:Desmin; D009418:S100 Proteins; D007633:Keratins