Dietary predictors of concentrations of polychlorinated biphenyls in breast adipose tissue of women living in Ontario, Canada.
The authors evaluated dietary predictors of concentrations of 11 polychlorinated biphenyls (PCBs) in breast adipose tissue from 190 women with benign breast disease who live in Ontario, Canada. Consumption of fish was positively correlated with, and the most consistent dietary predictor of, breast tissue PCB levels. Dietary predictors accounted for < 8% of the variation in breast adipose tissue PCB levels. Age was positively and most strongly associated with tissue PCB levels, perhaps representing long-term dietary intake and the complex interplay of absorption, metabolism, distribution, and excretion.
Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada.
Alicia
A
Paris-Pombo
Kristan J
KJ
Aronson
Christy G
CG
Woolcott
Will D
WD
King
D000273:Adipose Tissue / Q000737:chemistry*; D000367:Age Factors; D001706:Biopsy; D015992:Body Mass Index; D001940:Breast / Q000737:chemistry*; D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology; D016022:Case-Control Studies; D004032:Diet / Q000009:adverse effects; D002149:Energy Intake; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D017747:Seafood / Q000009:adverse effects; D011795:Surveys and Questionnaires
D004785:Environmental Pollutants; D011078:Polychlorinated Biphenyls