Needed: mouse/human cross validation of reinstatement/relapse models (and drug reward models) to model human substance abuse vulnerability allelic variants.
Molecular Neurobiology Branch, NIDA-IRP, NIH, Box 5180, Baltimore, MD 21224, USA. guhl@intra.nida.nih.gov.
George R
GR
Uhl
D000483:Alleles; D000818:Animals; D004195:Disease Models, Animal; D014644:Genetic Variation; D006801:Humans; D051379:Mice; D008960:Models, Psychological; D015203:Reproducibility of Results; D012201:Reward; D055502:Secondary Prevention; D019966:Substance-Related Disorders / Q000235:genetics* / Q000517:prevention & control / Q000523:psychology