Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Glucagon for the treatment of symptomatic beta blocker overdose.
A short cut review was carried out to establish whether the intravenous glucagon can support blood pressure in beta blocker overdose. A total of 51 papers were found using the reported search, of which six presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Boyd
R
R
Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Ghosh
A
A
D000319:Adrenergic beta-Antagonists / Q000506:poisoning*; D000328:Adult; D062787:Drug Overdose; D004630:Emergencies; D019317:Evidence-Based Medicine; D005260:Female; D005934:Glucagon / Q000627:therapeutic use*; D006801:Humans; D011433:Propranolol / Q000506:poisoning*; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000188:drug therapy
D000319:Adrenergic beta-Antagonists; D005934:Glucagon; D011433:Propranolol