Effect of an oral administration of Lactobacillus casei strain Shirota on the natural killer activity of blood mononuclear cells in aged mice.
The natural killer (NK) activity of blood mononuclear cells and splenocytes in aged mice fed on a diet containing Lactobacillus casei strain Shirota (LcS group) was significantly (P < 0.01) higher than that in mice fed on a diet without LcS. In the LcS group, there was a significant positive correlation (r = 0.63, P < 0.01) between the NK activity of blood mononuclear cells and the NK activity of splenocytes.
Hori
Tetsuji
T
Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi, Tokyo 186-8650, Japan. tetsuji-hori@yakult.co.jp
Kiyoshima
Junko
J
Yasui
Hisako
H
D000284:Administration, Oral; D000375:Aging / Q000276:immunology*; D000818:Animals; D005260:Female; D007694:Killer Cells, Natural / Q000276:immunology*; D007780:Lacticaseibacillus casei / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000166:cytology / Q000276:immunology