Controlling cell division in yeast and animals: does size matter?
In yeast, cell-size checkpoints coordinate cellular growth with cell-cycle progression. Now, evidence has been provided that such checkpoints probably do not exist in mammalian cells. These findings highlight an important difference between how yeast and animal cells proliferate in response to extracellular cues.
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA. ssgrewal@fhcrc.org
Savraj S
SS
Grewal
Bruce A
BA
Edgar
D000818:Animals; D002455:Cell Division / Q000502:physiology*; D048429:Cell Size; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000502:physiology*; D012583:Schwann Cells / Q000166:cytology* / Q000502:physiology*