Peripheral nerve complications in hemophilia.
OBJECTIVE
Muscle bleed in hemophilics can result in compressive neuropathy and permanent disability if not treated properly in time. Twenty cases of peripheral nerve involvement in hemophilics are presented with an aim to highlight its features and the role of pulsed ultrasound in the management.


METHODS
Between January, 1999 and 2000 June, 134 patients of bleeding disorders were examined. Twenty of them presented with features of nerve palsy. In addition to usual conservative treatment, pulse ultrasound electrotherapy of 10-15 sittings was used in all the cases.


RESULTS
Femoral nerve was involved in majority (15), followed by sciatic (4) and peroneal nerve in one case. Femoral nerve involvement was associated with iliacus bleed in 13 patients and inguinal bleed in two cases. All the four cases of sciatic nerve palsy were associated with gluteal hematoma. Only case of peroneal nerve palsy was associated with hematoma at upper leg and calf. Twelve cases improved completely within six months whereas another four recovered around 10 months. Remaining four showed only partial recovery even when followed up to 12 months.


CONCLUSIONS
Recognition of nerve complications in hemophilics is important to avoid long-term disability. Conservative therapy starting early was associated with favourable results. Pulsed ultrasound therapy at the site of haematoma helped in early regression of hematoma and neural recovery.
Department of Orthopaedics, Institute of Medical Sciences, Banaras Hindu University, Varanasi.
S K
SK
Saraf
O P
OP
Singh
V P
VP
Singh
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004599:Electric Stimulation Therapy; D005260:Female; D006467:Hemophilia A / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome