Engineering plants for nematode resistance.
Biotechnology offers sustainable solutions to the problem of plant parasitic nematode control. There are several possible approaches for developing transgenic plants with improved nematode resistance; these include anti-invasion and migration strategies, feeding-cell attenuation, and antinematode feeding and development strategies. The essential elements of an effective control strategy are (a) genes that encode an antinematode effector protein, peptide or interfering RNA and (b) promoters that direct a specific pattern of expression for that effector. This review summarizes information on effectors that act directly against the nematode as well as those aimed at disrupting the nematode feeding site. We discuss patterns of promoter activity that could deliver expression of these effectors in a restricted and directed manner. Societal opposition to the technology of GM-nematode control is also discussed.
Centre for Plant Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom. h.j.atkinson@leeds.ac.uk
Howard J
HJ
Atkinson
Peter E
PE
Urwin
Michael J
MJ
McPherson
D000818:Animals; D009348:Nematoda / Q000472:pathogenicity*; D018517:Plant Roots / Q000469:parasitology; D030821:Plants, Genetically Modified / Q000009:adverse effects / Q000469:parasitology*; D011480:Protease Inhibitors / Q000145:classification / Q000494:pharmacology; D034622:RNA Interference
D011480:Protease Inhibitors