[Study on the chemosensitivity test of human gastric cancer using the MTT assay].
OBJECTIVE
This study was conducted to investigate the chemosensitivity of gastric carcinoma.


METHODS
112 cases of fresh human gastric cancer samples were obtained for drug sensitivity testing using MTT.


RESULTS
The sensitivity sequence of antitumor agents was 5-Fu, DDP, MMC, etc. On the other hand, the sensitivity was relative to pathology and individual differences.


CONCLUSIONS
The MTT assay is an accurate system for determination of the chemosensitivity of tumor cells.
Chen
Z
Z
Department of General Surgery, First Affiliated Hospital, WCUMS, Chengdu 610041, China.
Hu
J
J
Chen
J
J
Yan
L
L
Mao
Y
Y
Zou
L
L
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002945:Cisplatin / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D005260:Female; D005472:Fluorouracil / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000494:pharmacology; D013274:Stomach Neoplasms / Q000473:pathology*; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D016685:Mitomycin; D002945:Cisplatin; D005472:Fluorouracil