[Use of color Doppler technique and estimation of CA 125 amd TPA levels in blood serum for the diagnosis of adnexal masses].
OBJECTIVE
The purpose of the study was to compare usefulness of color doppler technique and measurements of Ca 125 and TPA levels in differential diagnosis of adnexal masses.


METHODS
122 patients admitted and diagnosed due to presence of adnexal masses. Transvaginal scans with color doppler technique were performed Ca 125 and TPA levels in blood serum were measured. Morphological features of tumor during transvaginal scans were also noticed. Histopathological data after operation were collected and compared with preoperative scores.


RESULTS
22 adnexal masses were malignant. Presence of central vascularisation within the tumor and low Resistance Index and Pulsatility Index values were the best predictors of malignancy. Measurements of Ca 125 and TPA levels had worse predictive value ind diagnosis of adnexal masses.


CONCLUSIONS
Color doppler technique is a useful tool in diagnosis of adnexal masses and has higher sensitivity and specificity compared with measurements of Ca125, TPA levels and single tumor features achieved during transvaginal ultrasound.
Fuchs
Tomasz
T
Katedry i Kliniki Rozrodczości i Połoznictwa AM we Wrocławiu.
Michniewicz
Joanna
J
Zimmer
Mariusz
M
D000291:Adnexal Diseases / Q000000981:diagnostic imaging / Q000276:immunology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000276:immunology*; D011230:Precancerous Conditions / Q000000981:diagnostic imaging / Q000276:immunology; D011673:Pulsatile Flow; D019396:Tissue Polypeptide Antigen / Q000097:blood*; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D014655:Vascular Resistance
D018394:CA-125 Antigen; D019396:Tissue Polypeptide Antigen