[The involvement of endocrine disrupting chemicals in spermatogenic cell apoptosis].
Elimination of spermatogenic cells via apoptosis occurs spontaneously under normal physiologic conditions and is often aggravated after chemical-induced testicular impairment. A great amount of pollutants is released into the environment by modern industry, and many of these substances have been confirmed possessing reproductive toxicity, which can affect the reproduction and development of organism. These chemicals have been categorized to endocrine disrupting chemicals(EDCs). Studying spermatogenic cell apoptosis induced by EDCs will enrich and expand the pathway to identify EDCs, and will put forward new expounding of its mechanism. It has important meaning in the field of reproduction toxicology and male fertility.
Wang
Sheng
S
Department of Physiology, Medical College of Shantou University, Shantou, Guangdong 515031, China.
Qin
Da-Nian
DN
D017209:Apoptosis; D004703:Endocrine System / Q000166:cytology / Q000187:drug effects*; D004785:Environmental Pollutants / Q000633:toxicity*; D006801:Humans; D008297:Male; D012098:Reproduction / Q000187:drug effects; D013091:Spermatogenesis / Q000187:drug effects*
D004785:Environmental Pollutants