Infection with an extended-spectrum beta-lactamase-producing strain of Serratia marcescens following tongue reconstruction.
We report a case of postsurgical wound infection of polymicrobial etiology caused by Serratia marcescens and Pseudomonas aeruginosa following the use of a radial forearm free flap for oncological tongue reconstruction. S. marcescens was a producer of SHV-12 extended-spectrum beta-lactamase (ESBL). This is the first report from India of this ESBL. S. marcescens and P. aeruginosa were resistant to the empirical perioperative antibiotics administered. Delay in the recognition of the type of infection and in the institution of appropriate therapy resulted in total loss of the free flap.
Dhawan
Benu
B
Department of Microbiology, All India Institute of Medical Sciences, New Delhi-29, India.
Bonnet
Richard
R
Shukla
N K
NK
Mathur
Purva
P
Das
Bimal K
BK
Kapil
Arti
A
D000328:Adult; D005798:Genes, Bacterial; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000209:etiology; D019651:Plastic Surgery Procedures / Q000009:adverse effects; D016868:Serratia Infections / Q000209:etiology*; D012706:Serratia marcescens / Q000201:enzymology* / Q000235:genetics / Q000472:pathogenicity*; D013524:Surgical Flaps; D013530:Surgical Wound Infection / Q000209:etiology*; D014059:Tongue / Q000601:surgery*; D014062:Tongue Neoplasms / Q000601:surgery; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases