[Toxic epidermal necrolysis. A case for the burn intensive care unit].
Toxic epidermal necrolysis is a rare but life-threatening exfoliating disease of the skin and mucous membranes, commonly considered a drug sensitivity reaction. In this review of the literature we discuss the epidemiology, etiology, and pathology. We show diagnostic problems and current treatment strategies. Many of the problems associated with the disease, such as wound infection, sepsis, nutritional support, and pain management, are similar to problems in severely burned patients. Burn centers provide optimal logistics and knowledge to diagnose and treat this serious disease entity.
Spies
M
M
Klinik für Plastische, Hand- und Wiederherstellungschirurgie, Schwerverbranntenzentrum am Klinikum Oststadt, Medizinische Hochschule Hannover, Hannover. marcus.spies.oststadt@klinikum-hannover.de
Vogt
P M
PM
Herndon
D N
DN
D001684:Biological Dressings; D002053:Burn Units; D003131:Combined Modality Therapy; D003422:Critical Care; D003646:Debridement; D003937:Diagnosis, Differential; D006801:Humans; D010348:Patient Care Team; D016038:Skin Transplantation; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000601:surgery*