Pathogenesis of postoperative oral surgical pain.
Pain is a major postoperative symptom in many oral surgical procedures. It is a complex and variable phenomenon that can be influenced by many factors. Good management of oral surgical pain requires a detailed understanding of the pathogenesis of surgical pain. This article aims at reviewing postoperative pain from a broad perspective by looking into the nociception, neuroanatomy, neurophysiology, and neuropharmacology of pain. Therapeutic recommendations are made after reviewing the evidence from the literature for maximizing the efficacy of pain management techniques for oral surgical pain.
Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, National University of Singapore, Singapore. cliffong@pacific.net.sg
Cliff K S
CK
Ong
R A
RA
Seymour
D000700:Analgesics / Q000627:therapeutic use; D001921:Brain / Q000502:physiology; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology; D009055:Mouth / Q000601:surgery*; D009475:Neurons, Afferent / Q000502:physiology; D009619:Nociceptors / Q000502:physiology; D010149:Postoperative Pain / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D013116:Spinal Cord / Q000502:physiology; D014276:Trigeminal Nerve / Q000502:physiology
D000700:Analgesics; D018836:Inflammation Mediators