The use of enamel matrix protein in the treatment of localized aggressive periodontitis: a case report.
The previously named localized juvenile periodontitis (LJP), recently reclassified as localized aggressive periodontitis (LAP) seen in young people, is a rare condition characterized by severe periodontal destruction around first molars and incisors in individuals with little or no accumulation of visible plaque and/or calculus. Treatment of this condition has traditionally included periodontal surgery and adjunctive antibiotic therapy. Even though several periodontal regeneration techniques in these patients have been reported, there have been no reports of the use of the enamel matrix proteins in the treatment of intrabony defects caused by this disease. This report describes the case of a 15-year-old patient who was diagnosed as having LAP and the resulting treatment and outcome. The treatment consisted of systemic antibiotic therapy and periodontal surgical procedures combined with enamel matrix protein application. The 6-month clinical probing and attachment level measurements and radiographic findings are reported.
Department of Endodontics and Periodontics, University of Texas Health Science Center at Houston Dental Branch, 77030, USA.
Hernan
H
Bonta
Fernando
F
Llambes
Antonio J
AJ
Moretti
Hiru
H
Mathur
Otis J
OJ
Bouwsma
D000293:Adolescent; D010520:Aggressive Periodontitis / Q000150:complications / Q000188:drug therapy*; D016301:Alveolar Bone Loss / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery; D001861:Bone Regeneration; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins