[Anti-phospholipid syndrome nephropathy].
In the course of the antiphospholipid syndrome (APS), the renal involvement attributable to primary APS, APS nephropathy (APSN), corresponds to vaso-occlusive lesions of the intrarenal vessels, associated side-by-side, acute thromboses with chronic arterial and arteriolar lesions, leading to zones of cortical ischemic atrophy. A second retrospective study of 114 lupus patients was undertaken to determine whether APSN can be found in the course of systemic lupus and if there are biologic or clinical predictive factors of the presence of APSN. We showed the following
Service d'Anatomie Pathologique, Hôpital Européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris Cedex15. dominique.nochy@hop.egp.ap-hop-paris.fr
Dominique
D
Nochy
Eric
E
Daugas
Gary
G
Hill
Jean-Charles
JC
Piette
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis; D017152:Antibodies, Antiphospholipid / Q000032:analysis; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D008181:Lupus Nephritis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D008297:Male; D012079:Renal Circulation; D012189:Retrospective Studies; D012307:Risk Factors
D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor