Artifactually low glycated haemoglobin in a patient with severe hypertriglyceridaemia.
This report describes a case of artifactually low glycated haemoglobin (Hb) in a patient with type II diabetes and severe hypertriglyceridaemia. The effect of hypertriglyceridaemia on glycated Hb determination using the Abbott Vision method was investigated in a series of patients with diabetes. The interference of triglycerides in glycated Hb assays was also investigated by two other methods, the Beckman Synchron CX4 delta immunoturbidimetric method, and the Primus affinity chromatography high performance liquid chromatography assay.
Garrib
A
A
Department of Clinical Biochemistry and Diabetes, University Hospital Lewisham, Lewisham, London SE13 6LH, UK. alam.garrib@uhl.nhs.uk
Griffiths
W
W
Eldridge
P
P
Hatton
R
R
Worsley
A
A
Crook
M
M
D016477:Artifacts; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006452:Hemoglobinometry / Q000379:methods; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood* / Q000150:complications; D008875:Middle Aged
D006442:Glycated Hemoglobin