Anastrozole-induced remission of diaphragmatic paralysis from metastatic breast cancer treated with multiple prior therapies.
We describe a woman with metastatic breast cancer treated with multiple rounds of prior cytotoxic and endocrine therapies, who presented with ipsilateral diaphragmatic paralysis. The use of anastrozole, a highly selective nonsteroidal aromatase inhibitor (1 mg daily), successfully induced remission of metastatic tumors in our patient, who is partially recovering from diaphragmatic paralysis.
Suzuma
Takaomi
T
Department of Surgery, Affiliated Kihoku Hospital, Wakayama Medical University, 219 Myouji, Katsuragicho, Itogun, Wakayama 649-7113, Japan. suzuma@mail.wakayama-med.ac.jp
Sakurai
Takeo
T
Yoshimura
Goro
G
Umemura
Teiji
T
Shimizu
Yukio
Y
Yang
Qi-Feng
QF
Okamura
Yoshitaka
Y
D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000188:drug therapy* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000556:secondary / Q000628:therapy; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use*; D012074:Remission Induction; D012133:Respiratory Paralysis / Q000188:drug therapy* / Q000209:etiology; D014230:Triazoles / Q000627:therapeutic use*
D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole