[The effect of Chinese medicine yiqihuoxuetang on T-lymphocyte subpopulation in peripheral blood of infertile men with antisperm antibodies].
OBJECTIVE
To study whether Chinese Medicine Yiqihuoxuetang(YQHXT) could inhibit antisperm antibodies in infertile men, and to explore the therapeutical mechanism of YQHXT.


METHODS
Thirty infertile men with antisperm antibodies took YQHXT continuously for 60 days. Indirect immuno-fluorescence technique (IFT) was used to detect the levels of CD3, CD4, CD8 and CD4/CD8 ratio before and after treatment.


RESULTS
CD4 value and CD4/CD8 ratio after treatment were significantly lower than before treatment (P < 0.05); CD8 value became significantly higher(P < 0.05).


CONCLUSIONS
The results indicated that YQHXT could inhibit antisperm antibodies by keeping the balance of T-lymphocyte subpopulation in immunoinfertile men.
Ma
Hua-Gang
HG
Department of Andrology, Maternity and Infant Health Hospital, Weifang, Shandong 261011, China.
Xu
Ji-Xiu
JX
Zhang
Jian-Fa
JF
Zhang
Fang
F
Wang
Qing-Tu
QT
Xiong
Cheng-Liang
CL
D000328:Adult; D001323:Autoantibodies / Q000276:immunology; D016516:CD4-CD8 Ratio; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D007248:Infertility, Male / Q000276:immunology / Q000473:pathology*; D008297:Male; D016176:T-Lymphocyte Subsets / Q000187:drug effects*
D001323:Autoantibodies; D004365:Drugs, Chinese Herbal