Proton MR spectroscopy in Wernicke encephalopathy.
Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.
Servicio de Neurología, Buenos Aires, Argentina.
Carlos A
CA
Rugilo
Marcela C
MC
Uribe Roca
Maria C
MC
Zurru
Arístides A
AA
Capizzano
Gustavo A
GA
Pontello
Emilia M
EM
Gatto
D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000032:analysis; D001921:Brain / Q000473:pathology; D001923:Brain Chemistry; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D014899:Wernicke Encephalopathy / Q000175:diagnosis* / Q000378:metabolism
D001224:Aspartic Acid; D019344:Lactic Acid; C000179:N-acetylaspartate