A patient with postoperative mercury contamination of the peritoneum.
Peritoneal exposure to mercury has been rarely reported and long-term consequences of this type of exposure have not been documented. We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formication, pruritus, fatigue, irritiability, insomnia, alopecia, dizziness, a gait disturbance, loss of balance and multiple falls, abdominal pain, choking, and headaches. Two courses of chelation with dimercaptosuccinic acid using the standard protocol were undertaken, resulting in increased daily excretion, but without demonstrable objective or subjective benefit or lasting effect. She had multiple medical problems before the mercury intoxication, which complicates the attribution of all her problems to mercury intoxication. It is of particular interest that the patient survived and did not suffer any marked cognitive deterioration. She died in 2002 shortly after being diagnosed with lung cancer and declaring that she would fight it. Phasing out of mercury-weighted tubes is recommended.
North Country Occupational Medicine, Newport, Vermont, USA.
Nelson S
NS
Haas
Richard
R
Shih
Michael
M
Gochfeld
D002614:Chelating Agents / Q000627:therapeutic use; D003401:Creatine / Q000097:blood; D003424:Crohn Disease / Q000150:complications; D004569:Electroencephalography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy*; D007441:Intubation, Gastrointestinal; D007508:Irritable Mood; D008628:Mercury / Q000378:metabolism; D008630:Mercury Poisoning / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D020258:Neurotoxicity Syndromes / Q000209:etiology / Q000628:therapy; D010537:Peritoneum / Q000502:physiology; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D011859:Radiography; D004113:Succimer / Q000627:therapeutic use
D002614:Chelating Agents; D004113:Succimer; D008628:Mercury; D003401:Creatine