[Effects of +Gz exposure time on memory and behavior in rats].
OBJECTIVE
To explore the effect of +Gz exposure time on memory and behavior in rats.


METHODS
Twenty-four male SD rats were randomly divided into control group (A), +10 Gz/3 min group (B) and +10 Gz/5 min group (C). Rats in group A and B were exposed to +10 Gz for 3 min or 5 min respectively. Changes of memory and behavior in rats were observed after +Gz exposure.


RESULTS
As compared with control, percentage of right reflex decreased significantly and reaction time lengthened significantly immediately, 1 d, 2 d, 4 d and 6 d after +10 Gz/5 min exposure (P<0.01); reaction time lengthened significantly immediately and 2 d after +10 Gz/3 min exposure (P< 0.01). As compared with +10 Gz/3 min, percentage of right reflex decreased significantly and reaction time lengthened significantly at 1 d, 2 d, 4 d and 6 d after +10 Gz/5 min exposure (P<0.01). As compared with control and +10 Gz/3 min, time stayed in center grille lengthened significantly immediately after +10 Gz/5 min exposure (P<0.01); balancing function decreased significantly immediately and 2 d after +10 Gz/5 min exposure (P< 0.01).


CONCLUSIONS
It is suggested that +10 Gz/ 3 min exposure may induce a provisional disturbance in memory function and a change in behavior in rats, and +10 Gz/5 min exposure may induce a sustained disturbance in memory function and an obvious change in behavior in rats.
Wei
Ying-bo
YB
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China.
Sun
Xi-qing
XQ
Cao
Xin-sheng
XS
Yao
Yong-jie
YJ
Feng
Dai-ya
DY
Yang
Chang-bin
CB
D000054:Acceleration; D000818:Animals; D001522:Behavior, Animal; D018471:Hypergravity; D008297:Male; D008568:Memory / Q000502:physiology*; D004856:Postural Balance / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D011930:Reaction Time / Q000502:physiology*; D012018:Reflex / Q000502:physiology*; D013997:Time Factors