Effect of varicocele on testicular artery blood flow in men--color Doppler investigation.
OBJECTIVE
Varicocele can be defined as an abnormal tortuosity and dilatation of the veins of the pampiniform plexus. Contradictory results have been obtained from experimental animal models and a few clinical human studies on testicular arterial blood flow in varicocele. The purpose of this study was to determine the changes in testicular arterial blood flow parameters in patients with varicocele.


METHODS
A total of 62 patients with a clinical diagnosis of left varicocele and a scrotal vein with a diameter of > or = 3 mm on color Doppler ultrasonography were included in the study. A total of 44 fertile normal male volunteers served as controls.


RESULTS
Median testicular arterial blood flow and median flow rate in milliliters per minute per 100 g of testicular tissue were found to be significantly decreased in the patient group compared to the control group: blood flow, 1.42 and 2.00 ml/min; flow rate, 9.63 and 12.35 ml/min/100 g, respectively (p < 0.05). Positive correlations were found between sperm concentration and left testicular artery blood flow (p < 0.05) and between left testicular volume and testicular artery blood flow (p < 0.05).


CONCLUSIONS
Testicular arterial blood flow was found to be significantly decreased in men with varicocele. This may be a reflection of the impaired microcirculation. Following decreased testicular arterial blood flow, impaired spermatogenesis may result from defective energy metabolism in the microcirculatory bed.
Department of Radiology, Medical Faculty, Celal Bayar University, Manisa, Turkey. sertarhan@hotmail.com
Serdar
S
Tarhan
Bilali
B
Gümüs
Ilker
I
Gündüz
Veil
V
Ayyildiz
Cihan
C
Göktan
D000328:Adult; D001158:Arteries / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D006801:Humans; D018783:Impotence, Vasculogenic / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D012039:Regional Blood Flow / Q000502:physiology; D012307:Risk Factors; D013091:Spermatogenesis / Q000502:physiology; D013737:Testis / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000503:physiopathology; D018615:Ultrasonography, Doppler, Color; D014646:Varicocele / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*