Determining the incident electron fluence for Monte Carlo-based photon treatment planning using a standard measured data set.
An accurate dose calculation in phantom and patient geometries requires an accurate description of the radiation source. Errors in the radiation source description are propagated through the dose calculation. With the emergence of linear accelerators whose dosimetric characteristics are similar to within measurement uncertainty, the same radiation source description can be used as the input to dose calculation for treatment planning at many institutions with the same linear accelerator model. Our goal in the current research was to determine the initial electron fluence above the linear accelerator target for such an accelerator to allow a dose calculation in water to within 1% or 1 mm of the measured data supplied by the manufacturer. The method used for both the radiation source description and the patient transport was Monte Carlo. The linac geometry was input into the Monte Carlo code using the accelerator's manufacturer's specifications. Assumptions about the initial electron source above the target were made based on previous studies. The free parameters derived for the calculations were the mean energy and radial Gaussian width of the initial electron fluence and the target density. A combination of the free parameters yielded an initial electron fluence that, when transported through the linear accelerator and into the phantom, allowed a dose-calculation agreement to the experimental ion chamber data to within the specified criteria at both 6 and 18 MV nominal beam energies, except near the surface, particularly for the 18 MV beam. To save time during Monte Carlo treatment planning, the initial electron fluence was transported through part of the treatment head to a plane between the monitor chambers and the jaws and saved as phase-space files. These files are used for clinical Monte Carlo-based treatment planning and are freely available from the authors.
Department of Radiation Oncology, Virginia Commonwealth University, PO Box 980058, Richmond, Virginia 23298, USA. pjkeall@vcu.edu
Paul J
PJ
Keall
Jeffrey V
JV
Siebers
Bruce
B
Libby
Radhe
R
Mohan
D000465:Algorithms; D016880:Anisotropy; D003198:Computer Simulation; D004583:Electrons; D006801:Humans; D008168:Lung / Q000502:physiology*; D008954:Models, Biological; D015233:Models, Statistical; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D017785:Photons; D011874:Radiometry / Q000295:instrumentation / Q000379:methods* / Q000592:standards*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods* / Q000592:standards*; D012016:Reference Values; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D012984:Software; D014481:United States