R/qtl: QTL mapping in experimental crosses.
CONCLUSIONS
R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.


BACKGROUND
The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.
Broman
Karl W
KW
Department of Biostatistics, Johns Hopkins University, 615 N. Wolfe St, Baltimore, MD 21205, USA. kbroman@jhsph.edu
Wu
Hao
H
Sen
Saunak
S
Churchill
Gary A
GA
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics; D003433:Crosses, Genetic; D020869:Gene Expression Profiling / Q000379:methods*; D005819:Genetic Markers; D016678:Genome; D005838:Genotype; D006801:Humans; D007178:Inbreeding; D008390:Markov Chains; D008957:Models, Genetic; D015233:Models, Statistical; D040641:Quantitative Trait Loci / Q000235:genetics*; D012984:Software
D005819:Genetic Markers