Attitudes towards genetic screening for predisposition to colon cancer among cancer patients, their relatives and members of the community. Results of focus group interviews.
OBJECTIVE
To compare knowledge of and interest in genetic testing for hereditary colon cancer syndromes.


METHODS
Colorectal cancer patients, first-degree relatives of colon cancer patients and controls were recruited from a familial cancer registry. Focus groups explored attitudes about genetic testing.


RESULTS
All three groups conveyed interest in testing, but lacked knowledge about testing and its implications. After receiving information regarding the potential benefits and costs of testing (including insurance and employment issues) all three groups were disinclined to be tested. The reasons varied among risk groups.


CONCLUSIONS
When informed about the costs and implications of testing, individuals may be reluctant to undergo genetic testing, regardless of baseline risk. Barriers to testing will vary depending on the perceived risk of carrying a mutation.
Ramsey
Scott D
SD
Fred Hutchinson Cancer Research Center, Public Health Sciences Division, 1100 Fairview Avenue North, MP-900, PO Box 19024, University of Washington, Seattle, WA 98109, USA. sramsey@fhcrc.org
Wilson
Susan
S
Spencer
Anna
A
Geidzinska
Antoinette
A
Newcomb
Polly
P
D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D005190:Family; D005260:Female; D017144:Focus Groups; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000191:economics / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000523:psychology*