Anastrozole-induced remission of diaphragmatic paralysis from metastatic breast cancer treated with multiple prior therapies.
We describe a woman with metastatic breast cancer treated with multiple rounds of prior cytotoxic and endocrine therapies, who presented with ipsilateral diaphragmatic paralysis. The use of anastrozole, a highly selective nonsteroidal aromatase inhibitor (1 mg daily), successfully induced remission of metastatic tumors in our patient, who is partially recovering from diaphragmatic paralysis.
Department of Surgery, Affiliated Kihoku Hospital, Wakayama Medical University, 219 Myouji, Katsuragicho, Itogun, Wakayama 649-7113, Japan. suzuma@mail.wakayama-med.ac.jp
Takaomi
T
Suzuma
Takeo
T
Sakurai
Goro
G
Yoshimura
Teiji
T
Umemura
Yukio
Y
Shimizu
Qi-Feng
QF
Yang
Yoshitaka
Y
Okamura
D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000188:drug therapy* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000556:secondary / Q000628:therapy; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use*; D012074:Remission Induction; D012133:Respiratory Paralysis / Q000188:drug therapy* / Q000209:etiology; D014230:Triazoles / Q000627:therapeutic use*
D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole