Spinal epidural metastasis of cerebral oligodendroglioma.
A 50-year-old male patient with right frontal oligodendroglioma underwent subtotal resection on three separate occasions and, 10 months later, exhibited right frontal oligodendroglioma and extracranial metastasis. Spinal magnetic resonance imaging (MRI) demonstrated the existence of an enhancing mass lesion with evidence of posterior epidural compression at the 10th-11th thoracic level, not involving the vertebrae. A bone scan of the spine appeared normal, but showed evidence of hot uptake in the pelvis and femur. This report concerns a patient who developed a fatal and clinically unexplained, pancytopenia 3 months after the removal of a spinal epidural oligodendroglioma. Oligodendroglioma with metastasis outside the central nervous system is extremely rare, and only a few cases have previously been reported. A brief review of the literature with an emphasis on the mechanisms of tumor cell dissemination is presented.
Kim
Jin Gyun
JG
Department of Neurosurgery, College of Medicine, Inha Hospital, 7336 Tae Pyung-4 dong, Sujung-gu, Sungnam, Kyungkido 461-712, Korea.
Park
Chong Oon
CO
Hyun
Dong Keun
DK
Ha
Young Soo
YS
D001932:Brain Neoplasms / Q000473:pathology*; D004824:Epidural Space; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009837:Oligodendroglioma / Q000556:secondary*; D013120:Spinal Cord Neoplasms / Q000556:secondary*