Acne in Apert's syndrome: treatment with isotretinoin.
Apert's syndrome is an uncommon disease characterized by synostosis of extremities, vertebrae and skull. A clear association between Apert's syndrome and acne vulgaris with resistance to usual acne treatments has been described. A case of Apert's syndrome treated with oral isotretinoin with good results is reported and the pathogenic mechanisms of acne in this syndrome are discussed.
Department of Dermatology, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 La Coruña, Spain.
E
E
Cuerda
J
J
del Pozo
J
J
Rodrìguez-Lozano
C
C
Peña-Penabad
E
E
Fonseca
D000152:Acne Vulgaris / Q000188:drug therapy* / Q000473:pathology; D000168:Acrocephalosyndactylia; D000284:Administration, Oral; D001132:Arm; D001415:Back; D002648:Child; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D013909:Thorax
D003879:Dermatologic Agents; D015474:Isotretinoin