The role of oral appliances in treating obstructive sleep apnea.
BACKGROUND
Sleep-related breathing disorders are common and often are associated with vascular complications such as arterial hypertension, coronary heart disease and stroke. The most widely studied form of these disorders is obstructive sleep apnea. Patients usually are diagnosed with obstructive sleep apnea years after the onset of symptoms, which generally are nonspecific and include excessive daytime sleepiness, chronic fatigue and habitual snoring. The risk factors for sleep apnea are obesity, advancing age, male sex and maxillofacial abnormalities. This review focuses on the diagnosis and treatment of obstructive sleep apnea and, specifically, on the utility of oral appliances in the management of this disorder.


METHODS
The review is based on a MEDLINE search for articles in English on this topic. The article discusses results of randomized studies and prospective case series.


CONCLUSIONS
Several treatment options are quite effective. Nasal continuous positive airway pressure, with an overall acceptance rate of 70 percent, is the most widely used treatment modality. Maxillofacial surgery, although effective, is reserved for patients who have not responded to the more conventional therapies. Newer methods include application of oral appliances. Oral appliances have been shown to alleviate the severity of respiratory disturbances during sleep by about 60 percent, with an overall acceptance rate of 75 percent. The long-term complications generally are minor and are related to occlusal changes and temporomandibular joint discomfort.


CONCLUSIONS
With the advent of oral appliances, dentists are increasingly involved in managing the care of patients with sleep-related breathing disorders. Further studies are needed to determine the long-term complications of this type of intervention for the treatment of sleep-related breathing disorders.
Mohsenin
Neda
N
John B. Pierce Laboratory, New Haven, Conn., USA.
Mostofi
Mina T
MT
Mohsenin
Vahid
V
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008310:Malocclusion / Q000209:etiology; D019186:Mandibular Advancement / Q000295:instrumentation; D016382:Orthodontic Appliance Design; D009967:Orthodontic Appliances / Q000009:adverse effects; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000628:therapy*; D013705:Temporomandibular Joint Disorders / Q000209:etiology