Search for cytolethal distending toxin production among fecal Escherichia coli isolates from Brazilian children with diarrhea and without diarrhea.
The enteropathogenic role of cytolethal distending toxin-producing Escherichia coli was investigated by searching sequences homologous to the cdt genes of an O86 strain among 2,074 isolates from 200 children with acute diarrhea and 200 controls in Brazil. Only one (0.5%) diarrheic child and two (1.0%) non-diarrheic controls harbored cdt-positive isolates.
Seção de Bacteriologia, Instituto Adolfo Lutz, CEP 01246-902, São Paulo SP, Brazil. lmarques@ial.sp.gov.br
Lilian R M
LR
Marques
Ana T
AT
Tavechio
Cecília M
CM
Abe
Tânia A T
TA
Gomes
D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000633:toxicity; D001938:Brazil; D016022:Case-Control Studies; D002675:Child, Preschool; D003967:Diarrhea / Q000382:microbiology*; D004926:Escherichia coli / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005798:Genes, Bacterial; D006367:HeLa Cells; D006801:Humans; D007223:Infant; D012703:Serotyping
D001427:Bacterial Toxins; C067044:cytolethal distending toxin