GeneHopper: a web-based search engine to link gene-expression platforms through GenBank accession numbers.
Global gene-expression analysis is carried out using different technologies that are either array- or sequence-tag-based. To compare experiments that are performed on these different platforms, array probes and sequence tags need to be linked. An additional challenge is cross-referencing between species, to compare human profiles with those obtained in a mouse model, for example. We have developed the web-based search engine GeneHopper to link different expression resources based on UniGene clusters and HomoloGene orthologs databases of the National Center for Biotechnology Information (NCBI).
Svensson
B Anders T
BA
Center for Human and Clinical Genetics/Leiden Genome Technology Center, Leiden University Medical Center, The Netherlands.
Kreeft
Arja J
AJ
van Ommen
Gert-Jan B
GJ
den Dunnen
Johan T
JT
Boer
Judith M
JM
D000818:Animals; D019295:Computational Biology / Q000379:methods / Q000706:statistics & numerical data; D030561:Databases, Nucleic Acid / Q000706:statistics & numerical data*; D020869:Gene Expression Profiling / Q000706:statistics & numerical data*; D006801:Humans; D020407:Internet; D051379:Mice; D051381:Rats; D012984:Software