Eliminating trachoma in areas with limited disease.
The common wisdom is that a trachoma program cannot eliminate ocular chlamydia from a community, just reduce infection to a level where blindness would be minimal. We describe the success of multiple mass antibiotic treatments, demonstrating that complete elimination of infection may be an attainable goal in an area with modest disease.
WHO Collaborating Center, F.I. Proctor Foundation, Department of Ophthalmology, University of California-San Francisco, San Francisco, CA 94143, USA.
Bruce D
BD
Gaynor
Yinghui
Y
Miao
Vicky
V
Cevallos
Hem
H
Jha
J S P
JS
Chaudary
Ramesh
R
Bhatta
Susan
S
Osaki-Holm
Elizabeth
E
Yi
Julius
J
Schachter
John P
JP
Whitcher
Thomas
T
Lietman
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D017963:Azithromycin / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009390:Nepal / Q000453:epidemiology; D015995:Prevalence; D013997:Time Factors; D014141:Trachoma / Q000188:drug therapy* / Q000453:epidemiology* / Q000517:prevention & control
D000900:Anti-Bacterial Agents; D017963:Azithromycin