The global burden of measles in the year 2000--a model that uses country-specific indicators.
The estimation of the global burden of measles is challenging in the absence of reliable and comparable surveillance systems worldwide. A static model is described that enables estimation of measles morbidity, mortality, and disability for the year 2000 on the basis of country-specific information (i.e., demographic profile, vaccine coverage, and estimates of case-fatality ratios). This approach estimated a global incidence of 39.9 million measles cases, 777,000 deaths, and 28 million disability-adjusted life years. The World Health Organization regions of Africa and Southeast Asia had 70% of incident cases and 84% of measles-related deaths; 11 countries alone (Afghanistan, Burkina Faso, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Niger, Nigeria, Pakistan, Somalia, Uganda) account for 66% of deaths. This approach quantifies the measles burden by considering country-specific indicators, which can be updated, permitting an assessment of country, regional, and global changes in the burden associated with measles infection.
Stein
Claudia E
CE
Global Programme on Evidence for Health Policy, World Health Organization, Geneva, Switzerland. steinc@who.int
Birmingham
Maureen
M
Kurian
Mary
M
Duclos
Philippe
P
Strebel
Peter
P
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018563:Disease Notification; D006801:Humans; D017589:Immunization Programs / Q000592:standards*; D015994:Incidence; D007223:Infant; D008457:Measles / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D008458:Measles Vaccine / Q000008:administration & dosage*; D008459:Measles virus; D008954:Models, Biological; D015233:Models, Statistical; D019057:Quality-Adjusted Life Years; D014611:Vaccination / Q000592:standards; D014944:World Health Organization
D008458:Measles Vaccine