Study of the effect of Bronchipret on the lung function of five Austrian saddle horses suffering recurrent airway obstruction (heaves).
The effects of an oral preparation containing an extract of thyme and primula (Bronchipret; Bionorica) on the lung function of five horses suffering heaves were determined in a longitudinal study. The horses accepted the product well. The plasma concentrations of the marker substance, thymol, indicated that at least one of the substances in the extract had been absorbed from the gastrointestinal tract. The compliance, pulmonary pressure and airway resistance of the horses' lungs were all significantly improved after one month of treatment However, the severity of their clinical signs and their arterial oxygen partial pressure had not improved significantly.
van den Hoven
R
R
First Medical Clinic for Ungulates and Small Animals, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Zappe
H
H
Zitterl-Eglseer
K
K
Jugl
M
M
Franz
C
C
D000284:Administration, Oral; D000402:Airway Obstruction / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D006736:Horses; D008137:Longitudinal Studies; D008517:Phytotherapy; D010865:Pilot Projects; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D018517:Plant Roots; D031825:Primula; D012008:Recurrence; D012129:Respiratory Function Tests / Q000662:veterinary; D012720:Severity of Illness Index; D013943:Thymol / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D046930:Thymus Plant; D004338:Drug Combinations
D001993:Bronchodilator Agents; D010936:Plant Extracts; D013943:Thymol; C475160:thyme extract and ivy extract drug combination; D004338:Drug Combinations