Metastatic epithelioid gastrointestinal stromal tumor: yet another tumor with anemone cell features.
Since 1980 when Sibley and coworkers first described a nodal neoplasm of unknown histogenesis with striking surface microvilli for which they introduced the term "anemone cell," a series of reports have appeared in the literature illustrating tumors with similar ultrastructural features. While most reported cases showed differentiation along a particular line, rare cases remained histogenetically unclear. In this report a case is described of epithelioid gastric gastrointestinal stromal tumor metastatic to the liver, showing conspicuous long microvillus-type cell processes partially or circumferentially coating the cell surfaces, thus qualifying as yet another tumor type with anemone cell features.
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. shiaj@mskcc.org
Jinru
J
Shia
Robert A
RA
Erlandson
Cristina R
CR
Antonescu
D000293:Adolescent; D003964:Diaphragm / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary / Q000648:ultrastructure; D008854:Microscopy, Electron; D008871:Microvilli / Q000473:pathology / Q000648:ultrastructure; D010386:Pelvic Neoplasms / Q000473:pathology / Q000556:secondary; D016133:Polymerase Chain Reaction; D012509:Sarcoma / Q000473:pathology* / Q000648:ultrastructure; D013274:Stomach Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D017154:Stromal Cells / Q000473:pathology* / Q000648:ultrastructure