[Secretion of interleukin 2, 6 and tumor necrosis factor by peripheral blood mononuclear cells in patients with uveitis induced by phytohemagglutinin or lipopolysaccharide].
The aim of the study was to determine the concentration of selected cytokines secreted by peripheral blood mononuclear cells (PBMC) of patients with uveitis. We determined the spontaneous secretion and PHA- or LPS-induced production of IL-2, IL-6 and TNF in supernatants. The concentration of examined cytokines in patients with uveitis in comparison with healthy controls was not statistically significantly higher.
Katedra i Zakład Mikrobiologii AM we Wrocławiu.
Jolanta
J
Rusiecka-Ziółkowska
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000276:immunology* / Q000378:metabolism*; D015850:Interleukin-6 / Q000276:immunology* / Q000378:metabolism*; D007963:Leukocytes, Mononuclear / Q000276:immunology* / Q000378:metabolism*; D008070:Lipopolysaccharides / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D010835:Phytohemagglutinins / Q000008:administration & dosage / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology* / Q000378:metabolism*; D014605:Uveitis / Q000276:immunology*
D007376:Interleukin-2; D015850:Interleukin-6; D008070:Lipopolysaccharides; D010835:Phytohemagglutinins; D014409:Tumor Necrosis Factor-alpha