Occurrence of genotypes IV, V, VI and VIIa in Newcastle disease outbreaks in Germany between 1939 and 1995.
Forty-five velogenic Newcastle disease virus strains isolated in Germany between 1939 and 1995 were analysed by restriction enzyme digestion and sequencing to shed light on the relationships of past epizootics. Viruses derived from the period prior to 1970 belonged to a clade (IVea) of genotype IV comprising the earliest isolates from Europe, and could be isolated until the late seventies from poultry. Essex'70-like viruses, the prototype of genotype V, were already present at the beginning of the 1970-74 epizootic and in sporadic cases thereafter, indicating that these Newcastle disease outbreaks started in Western Europe. A genotype VI (subtype VIc) isolate was obtained in the early 1980s from a single outbreak in poultry. Outbreaks between 1993-95 were again part of a Western European epizootic caused by a genotype VIIa virus that was prevalent in the Far East.
Veterinary Medical Research Institute of the Hungarian Academy of Sciences, P. O. Box 18, 1581 Budapest, Hungary.
Eniko
E
Wehmann
Alíz
A
Czeglédi
Ortrud
O
Werner
E F
EF
Kaleta
B
B
Lomniczi
D000818:Animals; D001483:Base Sequence; D016000:Cluster Analysis; D004279:DNA, Viral / Q000737:chemistry; D004196:Disease Outbreaks / Q000662:veterinary*; D014644:Genetic Variation; D005838:Genotype; D005858:Germany / Q000453:epidemiology; D008969:Molecular Sequence Data; D009521:Newcastle Disease / Q000453:epidemiology / Q000821:virology*; D009522:Newcastle disease virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D011200:Poultry; D012367:RNA, Viral / Q000032:analysis / Q000737:chemistry; D015183:Restriction Mapping / Q000662:veterinary; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary
D004279:DNA, Viral; D012367:RNA, Viral