[Renal transplantation in donors over 60 years of age].
OBJECTIVE
To evaluate the impact of receptor's advanced age on kidney transplant outcomes.


METHODS
We reviewed all transplants performed between January 1990 and December 1999. Among 570 patients receiving grafts, 115 patients were 60 years or older at the time of transplantation. We compared this group with receptors younger than 60 years. We studied possible prognostic variables and compared patient and graft outcomes.


RESULTS
Mean age 63.81 (typical deviation (TD): 2.96). Mean follow-up time for elderly receptors was 41.6 months (TD: 26.58). 55.7% patients were males (p: 0.4). The most frequent cause for end stage renal disease was unknown etiology in group 1 and glomerular in the younger group (p: 0.01). 42% patients older than 60 years presented initial graft dysfunction, in comparison to 28.1% among younger than 60 (p: 0.006). Three-year graft survival was 90.42% for receptors 60 years old or older compared to 88.72% for group 2, without significant differences (p: 0.5). The most frequent graft loss etiology was patient death. (67.7%). (p = 0.005). Patient survival was 81.01% in group 1 and 95.25% in group 2, being differences significant (p < 0.001).


CONCLUSIONS
Renal grafts in receptors over the age of 60 years show a greater incidence of delayed graft function, although it doesn't seem to influence final graft survival. The most frequent cause for graft loss is receptor's death. Receptor's age does not represent a contraindication for transplant.
Gómez Vegas
Angel
A
Cátedra y Servicio de Urología, Hospital Clinico San Carlos, Madrid, España.
Blázquez Izquierdo
Jesús
J
Bocardo Fajardo
Gloria
G
San José Manso
Luis
L
Fernández Pérez
Cristina
C
Silmi Moyano
Angel
A
Resel Estevez
Luis
L
D000367:Age Factors; D000368:Aged; D015897:Comorbidity; D005260:Female; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D016016:Proportional Hazards Models; D013030:Spain / Q000453:epidemiology; D016019:Survival Analysis; D016896:Treatment Outcome