Contrast enhancement in Lhermitte-Duclos disease of the cerebellum: correlation of imaging with neuropathology in two cases.
Lhermitte-Duclos disease (LDD), also known as dysplastic gangliocytoma, is a rare cerebellar lesion. It has long been regarded as avascular. We report two patients with surgically proven LDD in whom contrast enhancement was observed on MRI. Neuropathological examination revealed proliferation of veins. We suggest that peripheral enhancement of LDD probably reflects vascular proliferation of the cerebellar venous draining system, and should be considered part of the imaging features of LDD.
Department of Radiology, Universitair Ziekenhuis Antwerpen, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium.
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L
Spaargaren
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P
Cras
M A M
MA
Bomhof
S T
ST
Lie
A M
AM
de Barsy
P H
PH
Croese
J L J M
JL
Teepen
V H J M
VH
Duwel
J W
JW
Van Goethem
O
O
Ozsarlak
L
L
van den Hauwe
A M
AM
De Schepper
P M
PM
Parizel
D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011856:Radiographic Image Enhancement; D014057:Tomography, X-Ray Computed
D003287:Contrast Media