Indocyanine green angiographic features in endogenous Candida chorioretinis.
BACKGROUND
To describe indocyanine green (ICG) angiography (ICGA) findings and clinical features of endogenous mycotic endophthalmitis.


METHODS
Two patients (a female 62 years, a male 31 years) were addressed to investigate a progressive unilateral visual loss. Slit-lamp examination disclosed a macular chorioretinitis. A clinical work-up revealed a mycotic infection (Candida albicans). Before treatment an ICGA was performed.


RESULTS
ICGA early frames disclosed hypofluorescent lesions. Progressively, the lesions were surrounded by a slight hyperfluorescence, although the centre of the lesions was still hypofluorescent.


CONCLUSIONS
The presence and persistence of a hypofluorescent lesion after introducing a specific treatment, led us to suspect a necrotic/ischaemic process affecting the choroidal vascular bed. ICGA provided additional information regarding the pathophysiological process and the patient's functional visual recovery.
Clinique d'ophtalmologie, Geneva, Suisse. Edoardo.Baglivo@hcuge.ch
Edoardo
E
Baglivo
C
C
Seghelmeble
M
M
Bagnoud
Peter M
PM
Leuenberger
Avinoam B
AB
Safran
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy; D002825:Chorioretinitis / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects
D000935:Antifungal Agents; D015725:Fluconazole; D007208:Indocyanine Green