[The role of tyrosine phosphorylation in the regulation of cell proliferation and differentiation in lower eukaryotes].
The review summarizes current data on signaling transduction mechanisms in some unicellular eukaryotes, based on sequential translation of phosphotyrosine signals from the cell surface to the nucleus.
Shemarova
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IV
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, St. Petersburg. irina@lis.mail.iephb.ru
D000595:Amino Acid Sequence; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D002455:Cell Division / Q000502:physiology*; D017124:Conserved Sequence; D004023:Dictyostelium / Q000502:physiology; D005057:Eukaryotic Cells / Q000166:cytology / Q000201:enzymology / Q000502:physiology*; D015971:Gene Expression Regulation, Enzymologic; D020935:MAP Kinase Signaling System / Q000235:genetics; D008969:Molecular Sequence Data; D010766:Phosphorylation; D019000:Phosphotyrosine / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary; D012441:Saccharomyces cerevisiae / Q000502:physiology; D015398:Signal Transduction; D013768:Tetrahymena / Q000502:physiology; D014443:Tyrosine / Q000378:metabolism*
D019000:Phosphotyrosine; D014443:Tyrosine