MCID/Low Disease Activity State Workshop: low disease activity state in rheumatoid arthritis.
The MCID (minimal clinically important difference) module of OMERACT 5 developed a research agenda that led to the conclusion that a state of low disease activity for rheumatoid arthritis (RA) would need to be defined. To develop such a definition the various concepts and terminologies, the process for developing an operational definition, and the availability and design of longitudinal datasets for validation needed to be considered. This article describes the process of the MCID/Low Disease Activity State Workshop at OMERACT 6 to develop such a definition.
Wells
George
G
Department of Clinical Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada.
Boers
Maarten
M
Shea
Beverley
B
Anderson
Jennifer
J
Felson
David
D
Johnson
Kent
K
Kirwan
John
J
Lassere
Marissa
M
Robinson
Vivian
V
Simon
Lee
L
Strand
Vibeke
V
van Riel
Piet
P
Tugwell
Peter
P
D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D017063:Outcome Assessment, Health Care; D012074:Remission Induction; D012720:Severity of Illness Index