Electrochemiluminescent determination of L-cysteine with a flow-injection analysis system.
A flow-injection electrochemiluminescent method for L-cysteine determination has been developed based on its enhancement of the electrochemiluminecence of luminol at a glassy carbon electrode. This method is simple and sensitive for cysteine determination. Under the selected experimental parameters, the linear range for cysteine concentration was 1.0 x 10(-6) - 5.0 x 10(-5) mol/l, and the detection limit was 0.67 micromol/l (S/N = 3). The relative standard deviation for 11 measurements of 1.0 x 10(-5) mol/l cysteine was 4.5%. The proposed method has been applied to the detection of cysteine in pharmaceutical injections with satisfactory results.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
Liande
L
Zhu
Yingxiu
Y
Li
Guoyi
G
Zhu
D003545:Cysteine / Q000032:analysis*; D004563:Electrochemistry / Q000379:methods*; D017022:Flow Injection Analysis / Q000379:methods*; D008163:Luminescent Measurements; D012680:Sensitivity and Specificity
D003545:Cysteine