Liposarcoma presenting as an intraluminal ureteral mass.
An 86-year-old woman with a previous excision of a large retroperitoneal low-grade liposarcoma presented with a 4-month history of persistent left flank discomfort. Workup revealed left hydronephrosis secondary to obstruction, which was caused by a recurrent liposarcoma in the intraluminal ureter. She underwent a left nephroureterectomy for symptomatic palliation. Pathologic study revealed high-grade liposarcoma. Despite negative surgical margins, the tumor rapidly recurred, leading to death only 4 months after surgery. This case highlights the aggressive nature of liposarcoma.
Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.
Ganesh V
GV
Raj
John F
JF
Madden
E Everett
EE
Anderson
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008080:Liposarcoma / Q000175:diagnosis* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000601:surgery; D010166:Palliative Care / Q000379:methods; D014516:Ureteral Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D014517:Ureteral Obstruction / Q000150:complications / Q000175:diagnosis* / Q000601:surgery