[Suspected epidemic at a hospital in Senegal].
Most outbreaks of noscomial infection are detected by means of molecular biological testing. However Euclidian distance is a rapid, reliable alternative if facilities for molecular biological testing are unavailable, as at the Principal Hospital in Dakar, Senegal. Over the 7 month period from 01/10/98 to 31/04/99, 110 of the 1033 blood cultures specimens collected in a group of 2360 children hospitalized in pediatric departments A and B of the Principal Hospital were found to be positive for Burkholderia cepacia. This high incidence suggested the possibility of an epidemic. This likelihood was further increased by evidence showing that all strains exhibited the same biotype and by results of pulsed-field electrophoresis (CHEF Mapper, Spel digestion) indicating that bacteria was of clonal origin. These findings were entirely consistent with those obtained by Euclidian distance but excessive mortality was not observed in the children involved. Testing of environmental specimens demonstrated the presence of the same strains in respirators and catheters. The most feasible hypothesis to account for these findings is environmental contamination resulting in mucocutaneous contamination of patients. Hemoculture containers were probably contaminated during handling.
De Pina
J J
JJ
Laboratoire de Biologie Clinique, Hôpital d'Instruction des Armées, Laveran, 13998 Marseille Armées, France.
Colbachini
P
P
Chapalain
J C
JC
Nicolas
P
P
Morillon
M
M
D019121:Burkholderia Infections / Q000175:diagnosis / Q000453:epidemiology*; D016956:Burkholderia cepacia; D002648:Child; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology*; D004196:Disease Outbreaks; D006801:Humans; D012675:Senegal / Q000453:epidemiology