Determinants of mid- and long-term results in patients after surgical revascularization for ischemic cardiomyopathy.
BACKGROUND
The revascularization of patients suffering from ischemic cardiomyopathy is possible with acceptable perioperative mortality and morbidity. Many publications have discussed the problem of predicting myocardial viability, whereas the quality of the peripheral coronary vessels has been focused on less frequently.


METHODS
We studied 908 consecutive patients with ischemic cardiomyopathy revascularized between January 1, 1988 and April 30, 2000. Death, recurrent heart failure, hospitalization due to cardiac causes, ventricular assist device implantation, heart transplantation, and ventricular arrhythmias were defined as adverse events. To analyze the importance of pre- and perioperative variables (state of the coronary arteries, myocardial viability, complete vs incomplete revascularization, urgency of the operation, previous operations, gender, diabetes, preoperative New York Heart Association class, age, number of grafts, and ischemic time), a proportional hazards model was used.


RESULTS
The most important predictors of short- and long-term event-free survival were the quality of the coronary arteries, followed by myocardial viability, complete revascularization, number of bypass grafts, and an elective operation.


CONCLUSIONS
The coronary vascular system can be described by means of a simple scoring system. A good or at least moderate coronary artery perfusing an area of dysfunctional yet viable myocardium is the main predictor of a successful perioperative course and an event-free survival. Patients with a poor coronary vasculature regardless of myocardial viability should not be considered suitable for revascularization.
Kleikamp
Georg
G
Department of Thoracic and Cardiovascular Surgery, Heart Center of Northrhine-Westfalia, University Hospital Ruhr-University Bochum, Bad Oeynhausen, Germany. gkleikamp@hdz-nrw.de
Maleszka
Ariane
A
Reiss
Nils
N
Stüttgen
Benjamin
B
Körfer
Reiner
R
D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000601:surgery*; D011379:Prognosis; D016016:Proportional Hazards Models; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000503:physiopathology