Cyclosporin A therapy for steroid-dependent Henoch-Schönlein purpura.
Henoch-Schönlein purpura is one of the most common types of systemic vasculitis in children. Although recurrence is frequent, most cases are benign and self-limited. Standard treatment consists of supportive care and nonsteroid antiinflammatory drugs and/or steroid. Here we report 2 cases of Henoch-Schönlein purpura, both of which had a prolonged and corticosteroid-dependent disease course. After treatment with cyclosporin A, the symptoms and signs subsided gradually in both cases with no recurrence after tapering of corticosteroid and cyclosporin A.
Department of Pediatrics, Taipei Municipal Hoping Hospital, Taiwan, ROC.
Dan-Ching
DC
Huang
Yao-Hsu
YH
Yang
Yu-Tsan
YT
Lin
Bor-Luen
BL
Chiang
D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D011695:IgA Vasculitis / Q000188:drug therapy*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D013256:Steroids / Q000008:administration & dosage; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D013256:Steroids; D016572:Cyclosporine