[Effect of smoking on the guanylin in the injured lung of rats].
In order to survey the influence of smoking on the level of guanylin in lung tissue in rats, a method of passive smoking was used to set up chronic bronchitis model in rats. The content of guanylin was measured by radioimmunoassay. In the smoking group, remarkable pathological changes in the lung tissue were found. There was no significant difference in the contents of guanylin in the plasma of experimental rats, compared with the control(P < 0.05). But in the lung tissue, the difference was significant(P < 0.01).
Pang
B
B
Beijing Red Cross Chaoyang Hospital, Beijing 100020, China.
Wang
C
C
Tang
C
C
Zhang
H
H
D000818:Animals; D029481:Bronchitis, Chronic / Q000378:metabolism; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D008297:Male; D045265:Natriuretic Peptides; D010455:Peptides / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D005768:Gastrointestinal Hormones; D045265:Natriuretic Peptides; D010455:Peptides; D014028:Tobacco Smoke Pollution; C072685:guanylin