The pre-operative assessment of the adnexal mass: the accuracy of clinical estimates versus clinical prediction rules.
OBJECTIVE
To evaluate the reproducibility of the clinical judgement of gynaecologists, gynaecologists in training and gynaecologic oncologists and to compare the predictive performance of the offhand assessment with the predictive performance of existing mathematical models for the pre-operative assessment of the adnexal mass.


METHODS
Questionnaire with paper cases of women operated on for an adnexal mass.


METHODS
Gynaecological unit in a teaching hospital in the South of The Netherlands.


METHODS
Women who underwent surgery for adnexal mass between January 1991 and December 1998.


METHODS
We offered 45 gynaecologists five different sets of 34 cases, with data on female age and menopausal status, a written description of the sonography, Doppler flow measurement and serum CA125 measurement. Nine observers for every set were asked to estimate the probability of malignancy.


METHODS
The reproducibility of the risk estimates as made by the participants was expressed with an intraclass correlation coefficients. The accuracy of the judgement of the clinicians and the result of mathematical models in the prediction of malignancy were expressed with sensitivity, specificity, and receiver-operating characteristic curves.


RESULTS
Neither clinically relevant nor statistically significant differences could be found between the accuracy of the risk assessments made by the clinicians and the accuracy of the risk assessments made by prediction models.


CONCLUSIONS
This study demonstrates that at this moment there is no need to introduce complicated predictive scoring systems such as neural networks or logistic regression models for the pre-operative assessment of the adnexal masses.
Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, The Netherlands.
Dorry
D
Boll
Peggy M A J
PM
Geomini
Hans A M
HA
Brölmann
Edith A
EA
Sijmons
Peter M
PM
Heintz
Ben W J
BW
Mol
D000290:Adnexa Uteri; D000291:Adnexal Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002983:Clinical Competence; D005260:Female; D006176:Gynecology; D006801:Humans; D008495:Medical Oncology; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods*; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000601:surgery