Atypical meningioma and extensive calvarium defects in neurofibromatosis type 1.
A 9-year-old girl with neurofibromatosis type 1 (NF1) presented with a massive atypical meningioma and calvarial defect. Skull radiographs and cranial CT showed an extensive lytic bone lesion at the vertex. MRI demonstrated a large mass invading the calvarium and sagittal sinus. The histopathological and immunohistochemical diagnosis of the resected mass was atypical meningioma. To our knowledge, this is the first case of NF1 associated with atypical meningioma and massive calvarial defect in a child.
Department of Paediatrics, Duzce Medical Faculty, Abant Izzet Baysal University, Konuralp-Duzce, Turkey. enversimsek62@yahoo.com
Enver
E
Simsek
Cevdet
C
Yavuz
Nil
N
Ustundag
D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000175:diagnosis / Q000209:etiology*; D009456:Neurofibromatosis 1 / Q000150:complications*; D012888:Skull Neoplasms / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed