Cyclosporin A therapy for steroid-dependent Henoch-Schönlein purpura.
Henoch-Schönlein purpura is one of the most common types of systemic vasculitis in children. Although recurrence is frequent, most cases are benign and self-limited. Standard treatment consists of supportive care and nonsteroid antiinflammatory drugs and/or steroid. Here we report 2 cases of Henoch-Schönlein purpura, both of which had a prolonged and corticosteroid-dependent disease course. After treatment with cyclosporin A, the symptoms and signs subsided gradually in both cases with no recurrence after tapering of corticosteroid and cyclosporin A.
Huang
Dan-Ching
DC
Department of Pediatrics, Taipei Municipal Hoping Hospital, Taiwan, ROC.
Yang
Yao-Hsu
YH
Lin
Yu-Tsan
YT
Chiang
Bor-Luen
BL
D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D011695:IgA Vasculitis / Q000188:drug therapy*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D013256:Steroids / Q000008:administration & dosage; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D013256:Steroids; D016572:Cyclosporine