[A case of gastric cancer with liver metastasis in which obstruction of the bile duct and choledocholithiasis was caused by intra-hepatic arterial infusion chemotherapy].
A 64-year-old man underwent gastrectomy and partial liver resection for gastric cancer and liver metastasis, and was administered intra-arterial infusion chemotherapy for metastases of the remnant liver. This treatment was very effective against the liver metastases, but 13 months after the operation obstructive jaundice occurred. An examination revealed obstruction of the bile duct and choledocholithiasis. The choledocholithiasis was treated using a percutaneous transhepatic cholangio-scope, and choledocho-duodenostomy was performed for the obstruction of the bile duct. Findings from the operation suggested that the obstruction was caused by the intra-arterial infusion chemotherapy. At present, 2 years after the first operation, the patient is alive without the regrowth of the liver metastasis.
Dept. of Surgery, Tsubame Rosai Hospital.
Kazuya
K
Yamaguchi
Kaoru
K
Miyashita
Kikuo
K
Aizawa
Hidekazu
H
Todoroki
Hidetoshi
H
Kiyonaga
D000804:Angiotensin II / Q000008:administration & dosage; D002779:Cholestasis / Q000209:etiology*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D042882:Gallstones / Q000209:etiology*; D005743:Gastrectomy; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery
D000804:Angiotensin II; D016685:Mitomycin