[Primary Sjögren's syndrome presenting with choreo-athetosis].
A 69-year-old man presenting with choreo-athetosis was proved to have primary Sjögren's syndrome. Choreo-athetosis suddenly appeared in the bilateral legs and the right arm; it was predominant in the right limbs. On the neurological examinations, there was no abnormal finding except for this involuntary movement. Brain MRI showed no abnormal finding. 18F-Fluorodeoxyglucose PET revealed that glucose metabolism was relatively increased in the bilateral striatum and thalamus (left side dominant). Dry eye and thirst were present for 4 years, and a diagnosis of primary Sjögren syndrome was confirmed by ophthalmological examinations, lip biopsy and sialography. Choreo-athetosis disappeared after thioridazine hydrochloride was started, while steroid was not effective.
Department of Neurology, Saitama Medical School.
Yoshihiko
Y
Nakazato
Toshimasa
T
Yamamoto
Naotoshi
N
Tamura
Kunio
K
Shimazu
Kenji
K
Ishii
D000368:Aged; D001264:Athetosis / Q000209:etiology*; D002819:Chorea / Q000209:etiology*; D006801:Humans; D008297:Male; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis