Long-term evaluation of esophageal function in patients treated at birth for esophageal atresia.
Dysphagia, gastroesophageal reflux (GER) and esophageal metaplasia are reported with various incidence in the long term follow-up of patients treated at birth for esophageal atresia (EA). To evaluate the long term outcomes 26 patients treated at birth for EA with Tracheo Esophageal Fistula (TEF) were examined 8-28 (mean 15.8) years later by clinical evaluation, including barium meal, fiberoptic upper GI endoscopy, 24 hour ambulatory two-channel pH-monitoring and stationary esophageal manometry. 50% of patients complained of dysphagia. Mild esophagitis was found in 20% of patients but GER was detected in only 16.7% of the cases. By morphological X-ray, esophageal anomalies were detected in 31% of cases without significant functional relevance. Hundred percent of patients had a disorganized peristaltic esophageal activity and a low amplitude of the esophageal contractions was observed in 58% of them. In our series, esophageal dismotilty seems to be the main consequence of EA without any relevant disturbance of normal nutritional habit.
Tomaselli
V
V
Department of Pediatric Surgery, Niguarda Ca' Granda Hospital, Milan, Italy. vpatom@libero.it
Volpi
M L
ML
Dell'Agnola
C A
CA
Bini
M
M
Rossi
A
A
Indriolo
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D003680:Deglutition Disorders / Q000453:epidemiology / Q000503:physiopathology; D004415:Dyspepsia / Q000453:epidemiology / Q000503:physiopathology; D004933:Esophageal Atresia / Q000503:physiopathology* / Q000601:surgery*; D004941:Esophagitis / Q000453:epidemiology / Q000503:physiopathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008365:Manometry; D015995:Prevalence; D014138:Tracheoesophageal Fistula / Q000453:epidemiology / Q000503:physiopathology