Cervico-mediastinal lymphadenopathy as a paradoxical response to chemotherapy in pulmonary tuberculosis. A case report.
We report a case of pulmonary tuberculosis who developed tuberculous mediastinal and later cervical lymphadenopathy while on antituberculous chemotherapy. She responded to the addition of oral corticosteroids to her regimen. The relevant literature regarding the pathogenesis, varied manifestations and the clinical importance of recognising a paradoxical response is discussed.
Janmeja
A K
AK
Department of Chest Diseases and Tuberculosis, Government Medical College and Hospital, Chandigarh, India.ashokjanmeja@hotmail.com
Das
S K
SK
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008206:Lymphatic Diseases / Q000139:chemically induced*; D011239:Prednisolone / Q000627:therapeutic use*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents; D005938:Glucocorticoids; D011239:Prednisolone