Microsurgical resection of nonocclusive salpingitis isthmica nodosa is beneficial.
OBJECTIVE
To determine the effect of microsurgical resection and tubocornual anastomosis (TCA) of nonocclusive salpingitis isthmica nodosa (SIN) on fertility and risk for ectopic pregnancy (EP).


METHODS
Prospective cohort.


METHODS
University-affiliated tertiary fertility clinic.


METHODS
Infertile women with hysterosalpingography evidence of SIN in patent fallopian tubes.


METHODS
Microsurgical resection and TCA for nonocclusive SIN.


METHODS
Occurrence of IUP and EP after TCA; comparison of duration of infertility preceding TCA with time to intrauterine pregnancy (IUP) after TCA; and comparison of numbers of women who conceived an EP before and after TCA.


RESULTS
Twelve (46%) of the women had IUPs with a mean time to pregnancy of 10.5 months, which is significantly shorter than the preceding period of infertility. Three women experienced EPs after TCA, which is reduced compared with the number of women with an EP preceding the TCA.


CONCLUSIONS
The significant decrease in time to conceive an IUP after surgery as compared with the duration of infertility before surgery and the apparent reduction in risk for EP after surgery demonstrate the benefit of TCA for resection of nonocclusive SIN.
Awartani
Khalid
K
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
McComb
Peter F
PF
D000328:Adult; D000714:Anastomosis, Surgical; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000601:surgery*; D008866:Microsurgery / Q000379:methods*; D011446:Prospective Studies; D012488:Salpingitis / Q000601:surgery*