[Comparison between human sperm zona-free hamster ovum penetration assay and in-vitro fertilization].
OBJECTIVE
The research question was whether the result of human sperm zona-free hamsterovum penetration assay (SPA) could serve as an indicator for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).


METHODS
The semen samples of 22 male partners in couples with infertile marriage were assessed for their fertilizing capacity by SPA. The fertilization rate of SPA was compared with that of IVF.


RESULTS
The fertilization rates of SPA and IVF were 38.6% +/- 23.5% and 53.5% +/- 28.4% respectively, and a significant correlation between SPA and IVF was observed (rs = 0.7045).


CONCLUSIONS
The result of SPA may be used as a reference indicator for assisting fertilization, IVF or ICSI.
Department of Physiology, School of Basic Medical Sciences, WCUMS, Chengdu 610041, China.
L
L
Yue
J
J
Zhang
Y
Y
He
P
P
Huang
L
L
Wang
W
W
Liu
L
L
Zhang
D000818:Animals; D006224:Cricetinae; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D008647:Mesocricetus; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000502:physiology*