Bilateral central anterior stromal opacity of the cornea: dystrophy or degeneration?
OBJECTIVE
To describe a bilateral, central, oval corneal opacity not resembling any known corneal degeneration or dystrophy.


METHODS
Ophthalmic examination, corneal topography, and pachymetry.


RESULTS
A 30-year-old woman presented complaining of blurred vision. Biomicroscopic examination revealed bilateral, centrally located, oval, diffuse opacification of the anterior corneal stroma. Corneal topography showed slightly paracentral corneal flattening and irregular astigmatism in both eyes. Pachymetry indicated thinning of the central cornea in the left eye. No evidence of systemic disease was found. Family members had no corneal abnormalities.


CONCLUSIONS
This unusual keratopathy closely resembles climatic proteoglycan stromal keratopathy. However, it is not clear whether the condition should be described as a dystrophy or degeneration.
Department of Ophthalmology, Medical School, Marmara University, Istanbul, Turkey. aetoker@superonline.com
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D000328:Adult; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis* / Q000235:genetics; D003318:Corneal Opacity / Q000175:diagnosis* / Q000235:genetics; D003319:Corneal Stroma / Q000473:pathology*; D019781:Corneal Topography / Q000379:methods; D005260:Female; D006801:Humans