[Celiac disease and fertility disorders in women].
OBJECTIVE
To determine incidence of subclinical forms of celiac disease in women with decreased fertility.


METHODS
Screening test.


METHODS
Department of Gynecology and Obstetrics, University Hospital, Palacký University, Olomouc.


METHODS
137 patients with fertility problems were included to the study. There were divided into two groups, patients with infertility and patients with repeated pregnancy loss. Screening test for celiac disease, serum level of antibodies tissue transglutaminase (tTGA) were performed in all of them. Positive test was confirmed by serological level of anti endomysium antibodies (EmA) and final diagnosis of silent celiac disease was done by enterobiopsy.


RESULTS
Celiac disease was found in two infertile patients (1.67%). In one patient the silent form was diagnosed by enterobiopsy. The second disease was latent form. In patients with repeated pregnancy loss we did not observe positive screening test.


CONCLUSIONS
We confirmed higher incidence of celiac disease in women with impaired fertility.
Machac
S
S
Centrum asistované reprodukce, Gynekologicko-porodnická klinika FN a LF UP, Olomouc.
Kolek
A
A
Dostál
J
J
Procházka
M
M
Oborná
I
I
Brezinová
J
J
Svobodová
M
M
Kudela
M
M
D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D012307:Risk Factors