Effect of resistant starch from corn or rice on glucose control, colonic events, and blood lipid concentrations in streptozotocin-induced diabetic rats.
To examine the effect of two types of resistant starch on blood glucose and insulin levels, colonic events, hypolipidemic actions and humoral immune responses, Sprague-Dawley streptozotocin-induced diabetic rats were fed diet containing resistant starch from corn or rice. The marked body weight loss by inducing diabetes was not recovered by feeding resistant starch, even though there are no differences in food intakes compared to the non-diabetic control rats. No significant effect of resistant starch feeding on blood glucose and insulin was found. Even though the length of small intestines, and cecum, colon and rectum together with the tissue weight of cecum were not affected by feeding resistant starch, the intestinal transit time was markedly shortened by both types of resistant starch and resistant starch from corn had a more pronounced effect. The short chain fatty acids in the intestinal contents did not appear to be different among the groups. Nonetheless, both of resistant starch from corn and rice significantly lowered plasma total lipid and cholesterol concentrations compared to the diabetic control. The total liver cholesterol lowering effect was observed with resistant starch from rice. Neither immunoglobulin G nor C(3) were influenced by resistant starch.
Kim
Woo K
WK
Dept of Food Science and Nutrition, Dankook University, San 8, Hannam-Dong, Youngsan-Gu, 140-714 Seoul, South Korea.
Chung
Mi K
MK
Kang
Nam E
NE
Kim
Myung H
MH
Park
Ock J
OJ
D000273:Adipose Tissue / Q000033:anatomy & histology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002432:Cecum / Q000473:pathology; D003106:Colon / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology; D003176:Complement C3 / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism* / Q000473:pathology; D004032:Diet; D004435:Eating; D004822:Epididymis; D005227:Fatty Acids / Q000032:analysis; D005772:Gastrointestinal Transit; D007074:Immunoglobulin G / Q000097:blood; D007328:Insulin / Q000097:blood; D007408:Intestinal Absorption; D008055:Lipids / Q000032:analysis / Q000097:blood; D008099:Liver / Q000737:chemistry; D008297:Male; D009929:Organ Size; D012275:Oryza / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012007:Rectum / Q000473:pathology; D013213:Starch / Q000493:pharmacokinetics / Q000494:pharmacology*; D015431:Weight Loss; D003313:Zea mays / Q000737:chemistry*
D001786:Blood Glucose; D003176:Complement C3; D005227:Fatty Acids; D007074:Immunoglobulin G; D007328:Insulin; D008055:Lipids; D013213:Starch