Evoked prefrontal gamma oscillation by hippocampal train stimulation in anesthetized rats.
We previously reported a difference in short-term synaptic plasticity between the rat posterior dorsal CA1 (pdCA1)-prefrontal cortex (PFC) and ventral CA1 (vCA1)-PFC pathways. Here, to determine the effects of hippocampal train stimulation on the local field potential in the medial PFC, we recorded the PFC field potential with brief 250-Hz train stimulation (1, 3, 5, 7, and 9 pulses) of pdCA1 or vCA1 in anesthetized rats. Analysis of the gamma-band (40-100 Hz) power revealed stimulation-evoked gamma oscillation in the pdCA1-PFC, but not in the vCA1-PFC. These results indicate that these pathways have different responses to train stimulation. The function of the pdCA1-PFC may differ from that of the vCA1-PFC, a well-known hippocampus-PFC pathway.
Department of Physiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511, Japan. yizaki@marianna-u.ac.jp
Yoshinori
Y
Izaki
Masahiko
M
Nomura
Tatsuo
T
Akema
D000758:Anesthesia; D000818:Animals; D004558:Electric Stimulation / Q000379:methods; D004569:Electroencephalography / Q000145:classification / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D009434:Neural Pathways / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D010507:Periodicity; D017397:Prefrontal Cortex / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013569:Synapses / Q000502:physiology