[Benefit/risk ratio of antibiotic therapy]
This publication evaluates critically the benefit/risk profile of several antibiotics currently at our disposal. The considered antibiotics are divided into pharmacological classes, because generally the drugs of the same class share the same adverse events. Moreover, the high therapeutic profile of the antibiotics puts them at the top of the safest drugs. Therefore the choice of an antibiotic is based above all on the evaluation of the patient and of the pathology to be treated, in terms of severity and possibility of achieving a response to treatment. An accurate anamnesis, the identification of the correct dosage and of the therapy duration minimise the potential risks of the chosen treatment. Detailed knowledge of the safety profile of these drugs is a further element in order for the antibiotic to perform at its best
Istituto di Farmacologia e Tossicologia, Facolta di Medicina e Chirurgia, II Universita degli Studi di Napoli, Italy.
F.
F
Rossi
M.
M
Mangrella
F.
F
Mazzeo