Plasma thrombomodulin levels in patients with Behçet's disease.
The plasma levels of thrombomodulin in 54 patients with Behçet's disease (BD) and 20 healthy control subjects were studied. The mean thrombomodulin (TM) level was significantly higher in active BD patients than in inactive patients and healthy controls ( P<0.001 and <0.01, respectively). Plasma TM levels did not show a significant relation with clinical manifestations. Increased plasma TM levels are associated with active disease and may reflect the presence of endothelial cell activation and/or injury.
Düzgün
Nurşen
N
Ankara University School of Medicine, Department of Internal Medicine, Clinical Immunology and Rheumatology, Ankara, Turkey. duzgun@medicine.ankara.edu.tr
Ayaşlioğlu
Ergin
E
Tutkak
Hüseyin
H
Sahin
Mehmet
M
Aydintuğ
Olcay
O
Olmez
Umit
U
D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D003078:Colchicine / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D018180:Thrombomodulin / Q000097:blood*
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D018180:Thrombomodulin; D011239:Prednisolone; D003078:Colchicine