Electrochemiluminescent determination of L-cysteine with a flow-injection analysis system.
A flow-injection electrochemiluminescent method for L-cysteine determination has been developed based on its enhancement of the electrochemiluminecence of luminol at a glassy carbon electrode. This method is simple and sensitive for cysteine determination. Under the selected experimental parameters, the linear range for cysteine concentration was 1.0 x 10(-6) - 5.0 x 10(-5) mol/l, and the detection limit was 0.67 micromol/l (S/N = 3). The relative standard deviation for 11 measurements of 1.0 x 10(-5) mol/l cysteine was 4.5%. The proposed method has been applied to the detection of cysteine in pharmaceutical injections with satisfactory results.
Zhu
Liande
L
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
Li
Yingxiu
Y
Zhu
Guoyi
G
D003545:Cysteine / Q000032:analysis*; D004563:Electrochemistry / Q000379:methods*; D017022:Flow Injection Analysis / Q000379:methods*; D008163:Luminescent Measurements; D012680:Sensitivity and Specificity
D003545:Cysteine