Acne in Apert's syndrome: treatment with isotretinoin.
Apert's syndrome is an uncommon disease characterized by synostosis of extremities, vertebrae and skull. A clear association between Apert's syndrome and acne vulgaris with resistance to usual acne treatments has been described. A case of Apert's syndrome treated with oral isotretinoin with good results is reported and the pathogenic mechanisms of acne in this syndrome are discussed.
Cuerda
E
E
Department of Dermatology, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 La Coruña, Spain.
del Pozo
J
J
Rodrìguez-Lozano
J
J
Peña-Penabad
C
C
Fonseca
E
E
D000152:Acne Vulgaris / Q000188:drug therapy* / Q000473:pathology; D000168:Acrocephalosyndactylia; D000284:Administration, Oral; D001132:Arm; D001415:Back; D002648:Child; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D013909:Thorax
D003879:Dermatologic Agents; D015474:Isotretinoin