Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio.
OBJECTIVE
The purpose of this study was to test the serotype distribution and antibiotic sensitivity patterns of group B Streptococcus from three Ohio regions in comparison to other areas of the United States.


METHODS
Three hundred forty-nine group B Streptococcus isolates from three Ohio hospitals were serotyped specifically, and disk diffusion was used to determine antibiotic susceptibility.


RESULTS
Serotype V was isolated most frequently (27%); major types Ia, Ib, II, and III had frequencies of 18%, 9%, 11%, and 17%, respectively. Erythromycin and clindamycin resistance was 12% (n = 200 isolates) and 8% (n = 49 isolates), respectively.


CONCLUSIONS
The prevalence shift of resistant serotype V group B streptococci in Ohio reflects regional increases and suggests that alternative therapies for patients who are allergic to penicillin may be inadequate.
Croak
Andrew
A
Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Irvine Hall, Athens, OH 45701, USA.
Abate
George
G
Goodrum
Kenneth
K
Modrzakowski
Malcolm
M
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology; D004351:Drug Resistance; D004917:Erythromycin / Q000494:pharmacology*; D005260:Female; D006801:Humans; D009820:Ohio; D011247:Pregnancy; D012703:Serotyping; D013292:Streptococcus agalactiae / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification; D014621:Vagina / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D004917:Erythromycin