Successful treatment of retrograde ejaculation with amezinium.
The effect of amezinium, a new type of antihypotensive agent, on retrograde ejaculation was evaluated in 3 patients with retrograde ejaculation. The patients received 10 mg amezinium orally once a day. All patients achieved antegrade ejaculation. Semen analyses revealed 6-50 x 10(6)/mL (mean 28.7 x 10(6)/mL) sperm with a motility of 20-50% (mean 36.7%). The wives of 2 patients became pregnant within 6 months of the initial treatment. None of the patients had any side effects. It would appear that amezinium is a useful treatment for retrograde ejaculation.
Ichiyanagi
O
O
Department of Urology, Yamagata University School of Medicine, Yamagata, Japan.
Sasagawa
I
I
Suzuki
Y
Y
Matsuki
S
S
Itoh
K
K
Miura
M
M
Tomita
Y
Y
D000328:Adult; D004542:Ejaculation / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011724:Pyridazines / Q000008:administration & dosage / Q000494:pharmacology*
D011724:Pyridazines; C027784:amezinium