Intestinal ischemia: molecular basis of detection and prevention.
It is well known that the small bowel is particularly sensitive to ischemia and reperfusion injury. In situations
such as mechanical occlusion, thromboembolism, sepsis, and low flow states, it is not uncommon to
subject the small bowel to transient yet potentially reversible ischemia. Surgeons involved in the treatment
of this entity are often faced with the dilemma - whether to cut or not, and to what extent should the
tissue be resected proximal and distal to the ischemic injury.
Yale University School of Medicine, New Haven, Conn.
U M
UM
Darr
J P
JP
Geiber