Chiari I malformation and cloacal exstrophy: report of a patient with both defects of blastogenesis.
We report on child with Chiari I malformation (CIM) and cloacal exstrophy, a combination of findings that has not been reported previously. CIM and cloacal exstrophy both demonstrate abnormalities that represent maldevelopment of the midline field. This combination of anomalies in this patient suggests an impairment of midline development during blastogenesis.
Tubbs
R Shane
RS
Pediatric Neurosurgery, Children's Hospital, Birmingham, Alabama 35233, USA. richard.tubbs@ccc.uab.edu
Smyth
Matthew D
MD
Oakes
W Jerry
WJ
D001921:Brain / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D002648:Child; D002987:Clitoris / Q000002:abnormalities* / Q000196:embryology / Q000503:physiopathology; D005260:Female; D006801:Humans; D011859:Radiography; D014621:Vagina / Q000002:abnormalities* / Q000196:embryology / Q000503:physiopathology