Intermolecular enol ether-alkyne metathesis.
[reaction: see text] A new intermolecular metathesis between a variety of alkynes and alkyl enol ethers is described. The best results were obtained with the second generation Grubbs' precatalysts. The reaction occurred with a high degree of regioselectivity and provided electron-rich dienes, which underwent a variety of [4 + 2] cycloadditions.
Department of Chemistry, University at Buffalo, the State University of New York, Buffalo, New York 14260, USA.
Anthony J
AJ
Giessert
Lee
L
Snyder
Jordan
J
Markham
Steven T
ST
Diver
D000480:Alkynes / Q000138:chemical synthesis*; D003500:Cyclization; D004583:Electrons; D004987:Ethers / Q000138:chemical synthesis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D017975:Ruthenium Compounds / Q000737:chemistry; D013237:Stereoisomerism
D000480:Alkynes; D004987:Ethers; D007202:Indicators and Reagents; D017975:Ruthenium Compounds