[In vivo measurement of rabbits brain impedance frequency response and the elementary imaging of EIT].
The in vivo measurements of rabbit brain tissue impedance were taken under both normal and ischemic conditions by using two-electrode measurement method in the frequency range from 0.1 Hz to 1 MHz. The dynamic images about the resistivity of cerebral ischemia were reconstructed based on a 16-electrode system. The results of in vivo measurement showed that the ratio of impedance increased can be as high as 75% at frequencies lower than 10 Hz. In the range from 1 KHz to 1 MHz, the ratio showed a constant value of 15%. The electrical impedance tomography (EIT) images obtained suggested that the regions of impedance changes highly correspond to the position of ischemia. It is confirmed that the brain function changes caused by local deficiency of blood can be detected and imaged by EIT method.
Department of Medical Electronic Engineering, Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an 710032. wxming@public.xa.sn.cn
Xiaoming
X
Wu
Xiuzhen
X
Dong
Mingxin
M
Qin
Feng
F
Fu
Yuemin
Y
Wang
Fusheng
F
You
Haiyan
H
Xiang
Ruigang
R
Liu
Xuetao
X
Shi
D000818:Animals; D001921:Brain / Q000502:physiology*; D002545:Brain Ischemia / Q000503:physiopathology; D017097:Electric Impedance; D005260:Female; D008297:Male; D011817:Rabbits; D014054:Tomography / Q000379:methods*