[Effect of calcium supplement on superoxide dismutase and malonaldehyde of disuse osteoporosis in young rats].
Effects of Ca supplement on the bone mineral density(BMD), red blood cell superoxide dismutase(SOD), plasma malonaldehyde(MDA) of disused osteoporosis were studied in this paper. Twenty five healthy pregnant SD rats were randomly divided into 5 groups, groups 2-5 were reproduced with patterns of animal osteoporosis. The diet in groups 1-2 was the basic diet, while the groups 3-5 experiment diets were supplemented with Ca. Selected 3 young rats, live with the mother rate each brood. The BMD, red blood cell SOD, plasma MDA were measured 37 d later. The results showed that BMD level of young rats in Ca supplement groups is higher than vigorous groups (P < 0.05). The MDA in vigorous group was higher than Ca supplement, groups(P < 0.01) and SOD was lower than high biologic calcium group(P < 0.05). It was suggested that Ca supplemented certain effect on red blood cell SOD, plasma MDA of disused osteoporosis.
Department of Cell Biology, Xinxiang Medical College, Xinxiang 453003, China.
Yuhui
Y
Tian
Wanli
W
Li
Guangfan
G
Hai
Yongxi
Y
Zhang
D000818:Animals; D000831:Animals, Newborn; D015519:Bone Density; D002118:Calcium / Q000494:pharmacology*; D002136:Calcium, Dietary / Q000494:pharmacology; D005260:Female; D008315:Malondialdehyde / Q000097:blood; D010024:Osteoporosis / Q000097:blood*; D011247:Pregnancy; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000097:blood*
D002136:Calcium, Dietary; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D002118:Calcium