Decoupling of autonomic and cognitive emotional reactions after cerebellar stroke.
Emotional blunting can be found after cerebellar lesions. However, the mechanism of such a modification is not clear. We present a patient with emotional flattening and increased risk taking after left cerebellar infarct who had an impaired autonomic reactivity to negative as compared with positive reinforcement. This impairment was demonstrated by the patient's undifferentiated skin conductance responses to negative and positive reinforcement, whereas controls produced larger skin conductance responses after negative feedback. The cooccurrence of emotional flattening and undifferentiated autonomic reactions to positively and negatively valenced stimuli strengthens the role of the cerebellum in the modulation of the autonomic responses.
Annoni
Jean-Marie
JM
Department of Neurology, Geneva University Hospital, Geneva, Switzerland. jean-marie.annoni@hcuge.ch
Ptak
Radek
R
Caldara-Schnetzer
Anne-Sarah
AS
Khateb
Asaid
A
Pollermann
Branka Zei
BZ
D000339:Affect; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D002531:Cerebellum / Q000473:pathology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D005712:Galvanic Skin Response / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D020521:Stroke / Q000150:complications* / Q000473:pathology*