Antisocial violent offenders with attention deficit hyperactivity disorder demonstrate akathisia-like hyperactivity in three-channel actometry.
Actometry enables quantitative and qualitative analysis of various hyperactivity disorders. Antisocial violent offenders have demonstrated diurnal increases in motor activity that may be related to attention deficit hyperactivity disorder (ADHD) that often precedes antisocial development. Motor restlessness in ADHD has common features with neuroleptic-induced akathisia. In this study, three-channel actometry was used to compare 15 antisocial violent offenders who had a history of ADHD with 15 healthy control subjects and 10 akathisia patients. The Barnes Akathisia Rating Scale (BARS) was used for clinical evaluation of akathisia symptoms. Ankle movement indices and the ankle-waist ratio differentiated the antisocial patients from the healthy controls significantly, with no overlap, and the same parameters expectedly differentiated the akathisia patients from the healthy controls. The repetitive, rhythmic pattern of akathisia was found in 13 of the 15 antisocial patients. Nine of the antisocial patients scored 2 or 3 (mild to moderate akathisia) on the BARS. Thus, the motor hyperactivity of antisocial ADHD patients has common features with mild akathisia. This may be due to a common hypodopaminergic etiology of ADHD and akathisia.
Helsinki University Central Hospital, Department of Psychiatry, Helsinki, Finland. katinka.tuisku@hus.fi
Katinka
K
Tuisku
Matti
M
Virkkunen
Matti
M
Holi
Hannu
H
Lauerma
Hannu
H
Naukkarinen
Ranan
R
Rimon
Kristian
K
Wahlbeck
D000293:Adolescent; D000328:Adult; D000368:Aged; D017109:Akathisia, Drug-Induced / Q000175:diagnosis / Q000503:physiopathology*; D000842:Ankle / Q000502:physiology; D000987:Antisocial Personality Disorder / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000209:etiology; D007734:Kymography; D035002:Lower Extremity / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D014953:Wrist / Q000502:physiology