[Macronodular adrenal hyperplasia: a case report].
This case report describes a 53-year old man with Cushing's syndrome due to Adrenocorticotropic Hormone (ACTH) independent bilateral adrenocortical macronodular hyperplasia (AIMAH). His plasma cortisol showed no diurnal rhythm and was unsuppressable by high-dose dexamethasone. Plasma ACTH was undetectable and did not respond to corticotrophin-releasing hormone. The aetiology of this rare disease remains uncertain. The treatment is based on bilateral adrenalectomy.
Clinique urologique A, centre hospitalier universitaire Avicenne, Rabat, Maroc.
A
A
Benchekroun
Y
Y
Nouini
M
M
Zannoud
H
H
el Kasmaoui
L
L
Benslimane
M
M
Faik
D000307:Adrenal Gland Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone; D003480:Cushing Syndrome / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006965:Hyperplasia; D008875:Middle Aged; D016896:Treatment Outcome
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone