Efficient chiral discrimination by 77Se NMR.
[reaction: see text] Several (77)Se NMR experiments were performed by titrating a sample of selenides with the chiral shift reagent methylbenzylamine (MBA), followed by acquisition of (77)Se NMR spectra. Eventually, we observed the appearance of two anisochronous resonances, with a relatively large separation, from 37 to 56 Hz, corresponding to the formation of the diastereomeric complexes. This methodology avoids derivatization processes, and the studied compound can be easily recovered from the NMR tube.
Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50670-901 Recife, PE, Brazil. pmenezes@ufpe.br
Paulo H
PH
Menezes
Simone M C
SM
Gonçalves
Fernando
F
Hallwass
Ricardo O
RO
Silva
Lothar W
LW
Bieber
Alfredo M
AM
Simas