Initiator-dependent chemoselective addition of THF radical to aldehyde and aldimine and its application to a three-component reaction.
[reaction: see text] The product distribution of the three-component reaction of aldehydes, arylamines, and THF was dependent on a radical initiator, preferentially giving the corresponding THF adducts of imines with dimethylzinc and adducts of aldehyde with triethylborane.
Yamada
Ken-Ichi
K
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
Yamamoto
Yasutomo
Y
Tomioka
Kiyoshi
K