Granular cell tumor occurring in the sigmoid colon treated by endoscopic mucosal resection using a transparent cap (EMR-C).
A case of granular cell tumor occurring in the sigmoid colon is reported. The patient, a 56-year-old man, visited our hospital for further evaluation of occult blood in his stool. Endoscopic examination revealed a yellowish, hemispheric submucosal tumor (SMT) with redness, about 6 mm in diameter, in the sigmoid colon. Endoscopic mucosal resection using a transparent cap (EMR-C) was performed, and histological examination revealed that the tumor consisted of a nested growth of large tumor cells with ample granular cytoplasm and small round nuclei. The tumor cells expressed S-100 protein and were stained with neuron-specific enolase (NSE) and periodic acid-Schiff, but were negative for desmin, vimentin, and cytokeratin. The resected tumor was diagnosed as a granular cell tumor. This may be the first report of a colorectal granular cell tumor successfully treated with EMR-C.
Endo
Shinji
S
Department of Internal Medicine, National Shikoku Cancer Center, 13 Horinouchi, Matsuyama 790-0007, Japan.
Hirasaki
Shoji
S
Doi
Toshihiko
T
Endo
Hisashi
H
Nishina
Tomohiro
T
Moriwaki
Toshikazu
T
Nakauchi
Masahito
M
Masumoto
Toshikazu
T
Tanimizu
Masahito
M
Hyodo
Ichinosuke
I
D003113:Colonoscopy; D003937:Diagnosis, Differential; D019160:Endosonography; D016586:Granular Cell Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome