[Histopathological observation of acute facial nerve impairment in rabbits].
OBJECTIVE
To investigate histopathological changes of acute facial nerve impairment.


METHODS
Ligation of facial nerve outside stylomastoid foramen with 3-0 silk, observation of histopathological changes of facial nerve on the 1st day, 3rd day and 5th day after ligation.


RESULTS
The facial nerve showed all kinds and various degrees of histopathological changes, from swelling to degeneration, in myeline and axon respectively.


CONCLUSIONS
All kinds and various degrees of pathological changes have been observed in myeline and axon after the ligation of facial nerve in rabbits. This study demonstrates that such injuries to the facial nerve become increasingly serious as the ligation lasts day after day.
Department of Otolaryngology, First Affiliated Hospital, WCUMS, Chengdu 610041, China.
K
K
Wang
L
L
Xu
D
D
Luo
B
B
Xiao
D000818:Animals; D005154:Facial Nerve / Q000473:pathology*; D020220:Facial Nerve Injuries / Q000473:pathology*; D005260:Female; D008297:Male; D011817:Rabbits; D013997:Time Factors