[Drug bradyarrhythmias as a cause of hospital admission. Study of 83 cases].
OBJECTIVE
The frequency and circumstances associated with drugs-induced bradiarrhythmia (DB) causing hospital admission are little known.


METHODS
Retrospective analyses of DB in Cardiology (CD) and Internal Medicine (IMD) Departments of a 3rd level hospital over two consecutive years.


RESULTS
We detected 83 cases (mean age: 72.68, 75.9% women). Most frequent DB was slow atrial fibrillation (55.4%). DB were due to the use of one drug in 41 cases and to an association in 42 cases. Most frequently involved drug was digoxine (62.7%). DB were due to the use of one drug in 41 cases and to an association in 42 cases. Most frequently involved drug was digoxine (62.7%), which was commonly associated with another drug (69.3%). Most frequent pharmacological associations were negative chronotropic drugs (57.1%) followed by their association with a diuretic and/or an angiotensin converting enzyme inhibitor (42.8%), causing renal failure and/or potassium imbalance.


CONCLUSIONS
Drugs-induced bradiarrhythmia is a frequent cause of hospital admission in aged people, especially women, and is frequently due to drugs associations and/or renal failure.
Cabezón Ruiz
Soledad
S
Servicio de Cardiología. Hospital Universitario Virgen del Rocío. Sevilla. Spain. scabezonruiz@hotmail.com
Morán Risco
Juan Enrique
JE
Pedrote Martínez
Alonso
A
Errazquin Sáenz de Tejada
Francisco
F
Cayuela
Aurelio
A
Barón-Esquivias
Gonzalo
G
D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000453:epidemiology / Q000534:rehabilitation*; D001919:Bradycardia / Q000139:chemically induced* / Q000453:epidemiology / Q000534:rehabilitation*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology