Effect of a mixture of conjugated linoleic acid isomers on growth performance and antibody production in broiler chicks.
The effect of dietary conjugated linoleic acid (CLA) isomers mixture on antibody titres against sheep blood erythrocytes (SRBC) and immunoglobulin (Ig) G concentration in plasma was studied in broiler chickens. In experiment 1, male and female broiler chicks (11 d of age, Cobb strain) were fed a diet supplemented with 10 g CLA or 10 g safflower-seed oil/kg diet for 2 weeks. An SRBC suspension (5:100, v/v) in a phosphate buffer was intravenously injected at 18 d of age and a blood sample was taken from the wing vein at 25 d of age. Chicks fed the CLA-supplemented diet had enhanced first antibody titres in plasma to SRBC as compared with those fed the safflower-seed oil-supplemented diet, irrespective of sex differences. In experiment 2, male broiler chicks (8 d of age, Ross strain) were fed a basal diet or a diet containing 10 g CLA/kg diet for 3 weeks. CLA in the CLA diet partially replaced the soyabean oil in the basal diet. The SRBC suspension was intravenously injected at 15 and 25 d of age and a blood sample was obtained at 21 and 29 d of age. The first antibody titres against SRBC were higher in chicks fed the CLA diet than those in chicks fed the basal diet, but the second titres were not. Plasma IgG concentrations in chicks fed the CLA diet were higher than those in chicks fed the basal diet on both sampling days. The results showed that dietary CLA enhanced antibody production in broiler chickens.
Department of Animal Science, Faculty of Agriculture, Tohoku University, Tsutsumidori-Amamiya-machi 1-1, Aoba-ku, Sendai-shi 981-8555, Japan. taka@bios.tohoku.ac.jp
Kazuaki
K
Takahashi
Yukio
Y
Akiba
Toshio
T
Iwata
Masaaki
M
Kasai
D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002645:Chickens / Q000254:growth & development* / Q000276:immunology*; D004032:Diet; D019587:Dietary Supplements; D004435:Eating; D005260:Female; D006388:Hemagglutinins / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007536:Isomerism; D008041:Linoleic Acids / Q000008:administration & dosage*; D008297:Male; D011897:Random Allocation; D012450:Safflower Oil / Q000008:administration & dosage; D015430:Weight Gain
D006388:Hemagglutinins; D007074:Immunoglobulin G; D008041:Linoleic Acids; D012450:Safflower Oil