title: Long-term angiographic recurrences after selective endovascular treatment of aneurysms with detachable coils.
abstract: OBJECTIVE
  Our aim in this study was to assess the incidence and determining factors of angiographic recurrences after endovascular treatment of aneurysms.
  
  
  METHODS
  A retrospective analysis of all patients with selective endosaccular coil occlusion of intracranial aneurysms prospectively collected from 1992 to 2002 was performed. There were 501 aneurysms in 466 patients (mean+/-SD age, 54.20+/-12.54 years; 74% female). Aneurysms were acutely ruptured (54.1%) or unruptured (45.9%). Mean+/-SD aneurysm size was 9.67+/-5.91 mm with a 4.31+/-1.97-mm neck. The most frequent sites were basilar bifurcation (27.7%) and carotid ophthalmic (18.0%) aneurysms. Recurrences were subjectively divided into minor and major (ideally necessitating re-treatment). The most significant predictors of angiographic recurrence were determined by logistic regression. These results were confirmed by chi2, t tests, or ANOVAs followed, when appropriate, by Tukey's contrasts.
  
  
  RESULTS
  Short-term (< or =1 year) follow-up angiograms were available in 353 aneurysms (70.5%) and long-term (>1 year) follow-up angiograms, in 277 (55%), for a total of 383 (76.5%) followed up. Recurrences were found in 33.6% of treated aneurysms that were followed up and that appeared at a mean+/-SD time of 12.31+/-11.33 months after treatment. Major recurrences presented in 20.7% and appeared at a mean of 16.49+/-15.93 months. Three patients (0.8%) bled during a mean clinical follow-up period of 31.32+/-24.96 months. Variables determined to be significant predictors (P<0.05) of a recurrence included aneurysm size > or =10 mm, treatment during the acute phase of rupture, incomplete initial occlusions, and duration of follow-up.
  
  
  CONCLUSIONS
  Long-term monitoring of patients treated by endosaccular coiling is mandatory.
authors.affiliation: Department of Radiology, Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, 1560 Sherbrooke East, Room M-8203-1, Montreal, Quebec, H2L 4M1, Canada. dr_jean_raymond@hotmail.com
authors.forename: Jean
authors.initials: J
authors.lastname: Raymond
authors.forename: François
authors.initials: F
authors.lastname: Guilbert
authors.forename: Alain
authors.initials: A
authors.lastname: Weill
authors.forename: Stavros A
authors.initials: SA
authors.lastname: Georganos
authors.forename: Louis
authors.initials: L
authors.lastname: Juravsky
authors.forename: Anick
authors.initials: A
authors.lastname: Lambert
authors.forename: Julie
authors.initials: J
authors.lastname: Lamoureux
authors.forename: Miguel
authors.initials: M
authors.lastname: Chagnon
authors.forename: Daniel
authors.initials: D
authors.lastname: Roy
mesh_terms: D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000628:therapy*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D013995:Time; D017211:Treatment Failure; D014656:Vascular Surgical Procedures / Q000009:adverse effects