The impact of learning of a genetic predisposition to nicotine dependence: an analogue study.
OBJECTIVE
To examine the consequences of informing smokers of a genetic predisposition to nicotine dependence and of providing treatment efficacy information tailored to genetic status.


METHODS
Analogue study using four vignettes; 2 (genetic status) x 2 (whether treatment efficacy information provided) between subjects design.


METHODS
269 British adult smokers.


METHODS
Preferred cessation methods and perceived control over quitting.


RESULTS
Gene positive participants were significantly more likely to choose the cessation method described as effective for their genetic status, but significantly less likely to choose to use their own willpower. Providing tailored treatment information did not alter these effects. Perceived control was not significantly affected by either genetic status or information provision.


CONCLUSIONS
Learning of a genetic predisposition to nicotine dependence may increase desire for effective cessation methods, but may undermine the perceived importance of willpower in stopping smoking.
Wright
A J
AJ
Psychology & Genetics Research Group, Guy's, King's & St Thomas's School of Medicine, London, UK. alison.wright@kcl.ac.uk
Weinman
J
J
Marteau
T M
TM
D000328:Adult; D000368:Aged; D001294:Attitude to Health; D002755:Choice Behavior; D005260:Female; D020022:Genetic Predisposition to Disease; D006266:Health Education; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D010465:Perception; D012907:Smoking / Q000235:genetics* / Q000523:psychology; D016540:Smoking Cessation / Q000379:methods / Q000523:psychology; D014029:Tobacco Use Disorder / Q000235:genetics*