Copper-catalyzed synthesis of unsymmetrical triarylphosphines.
Various triarylphosphines have been prepared by coupling diphenylphosphine with aryl iodides with catalytic amounts of CuI in the presence of either K(2)CO(3) or Cs(2)CO(3), in good yields. This method can tolerate a variety of functional groups and does not require the use of expensive additives, or harsh reaction conditions, and is palladium free.
Allen
Derek Van
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Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, 01003, USA. dv@chem.umass.edu
Venkataraman
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