title: Beating heart surgery reduces mortality in the reoperative bypass patient.
abstract: BACKGROUND
  Reoperative coronary artery bypass grafting (redo-CABG) has an increased operative morbidity and mortality compared to patients undergoing primary revascularization. In an effort to reduce the hazards of reoperative CABG, we commenced revascularizing selected patients without cardiopulmonary bypass (CPB) as an alternative to conventional approaches.
  
  
  METHODS
  From January 1998 to Dec. 2000, 432 patients underwent reoperative CABG, 153 patients (35%) without the aid of CPB. Treatment groups were compared by means of univariate analysis for preoperative risk factors and postoperative complications. Predicted risk and risk-adjusted mortality were determined by the Society of Thoracic Surgeons risk algorithm.
  
  
  RESULTS
  There was a significant difference in the preoperative predicted risk scores between the two treatment groups (off pump 6.5% vs. on pump 5.4%, p=0.0343). There was a significant difference in the off pump observed mortality (2.61%) versus the on pump group (9.68%, p=0.0065). Decreased morbidity in the off pump group was evidenced by a reduced need for blood products (25% vs. 67%, p<0.0001), and the incidence of prolonged ventilation (4% vs. 14%, p=0.0032). The off pump group also had shorter hospital stays (6.2 +/- 5.96 days vs. 8.0 +/- 7.82, p=0.0091). No significant differences between the two groups were seen in the prevalence of perioperative myocardial infarction, stroke, renal failure, or reoperation for bleeding.
  
  
  CONCLUSIONS
  Bypass grafting without CPB significantly decreases mortality and morbidity in selected reoperative patients, and should be considered a viable alternative to conventional approaches.
authors.affiliation: Cardiopulmonary Research Science and Technology Institute, Dallas, Texas, USA. Tdewey@CNANT.com
authors.forename: T M
authors.initials: TM
authors.lastname: Dewey
authors.forename: M J
authors.initials: MJ
authors.lastname: Magee
authors.forename: T
authors.initials: T
authors.lastname: Acuff
authors.forename: S
authors.initials: S
authors.lastname: Prince
authors.forename: M
authors.initials: M
authors.lastname: Herbert
authors.forename: J R
authors.initials: JR
authors.lastname: Edgerton
authors.forename: M J
authors.initials: MJ
authors.lastname: Mack
mesh_terms: D000704:Analysis of Variance; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D012086:Reoperation / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D013249:Sternum / Q000601:surgery; D013908:Thoracotomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality