title: History of the development and evolution of local anesthesia since the coca leaf.
authors.affiliation: Departmento de Profilaxis, Odontopediatría y Ortodoncia, Facultad de Odontología, Universitdad de Complutense de Madrid, Spain. ciglesuela@terra.es
authors.forename: Jesús
authors.initials: J
authors.lastname: Calatayud
authors.forename: Angel
authors.initials: A
authors.lastname: González
mesh_terms: D000766:Anesthesia, Dental / Q000266:history; D000772:Anesthesia, Local / Q000266:history*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects / Q000266:history*; D003041:Coca / Q000737:chemistry*; D003042:Cocaine / Q000008:administration & dosage / Q000009:adverse effects / Q000266:history; D004345:Drug Industry / Q000266:history / Q000639:trends; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D013594:Syringes / Q000266:history
chemical_list: D000779:Anesthetics, Local; D003042:Cocaine