title: Increased phase synchronization of spontaneous calcium oscillations in epileptic human versus normal rat astrocyte cultures.
abstract: Stochastic synchronization analysis is applied to intracellular calcium oscillations in astrocyte cultures prepared from epileptic human temporal lobe. The same methods are applied to astrocyte cultures prepared from normal rat hippocampus. Our results indicate that phase-repulsive coupling in epileptic human astrocyte cultures is stronger, leading to an increased synchronization in epileptic human compared to normal rat astrocyte cultures.
authors.affiliation: Center for Neurodynamics, University of Missouri at St. Louis, St. Louis, Missouri 63121, USA.
authors.forename: Gábor
authors.initials: G
authors.lastname: Balázsi
authors.forename: Ann H
authors.initials: AH
authors.lastname: Cornell-Bell
authors.forename: Frank
authors.initials: F
authors.lastname: Moss
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000378:metabolism* / Q000473:pathology; D001921:Brain / Q000378:metabolism / Q000473:pathology; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling; D002450:Cell Communication; D002478:Cells, Cultured; D004827:Epilepsy / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008954:Models, Biological; D009991:Oscillometry / Q000379:methods; D051381:Rats; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D002118:Calcium