The diagnostic value of troponin T and myoglobin levels in acute myocardial infarction: a study in Turkish patients.
This study compares the diagnostic value of troponin T (TnT) and myoglobin with creatinine kinase (CK) for myocardial infarction (MI) in a tertiary care centre in a developing nation. The study group comprised 33 acute myocardial infarction patients and 27 healthy controls. Receiver operating characteristic curves for TnT, myoglobin and CK were drawn and areas under the curve calculated. At admission, myoglobin levels had greater diagnostic sensitivity than TnT or CK levels. After 2 h, myoglobin and TnT had equal sensitivity and specificity, whereas CK still had lower sensitivity than myoglobin and TnT. After 4 h there was no difference between the tests. It was concluded that myoglobin levels on admission and TnT at 2 h had the greatest diagnostic rate, whereas all the tests were similar after 4 h for MI.
Vatansever
S
S
Department of Internal Medicine, Division of Emergency Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. sezai@istanbul.edu.tr
Akkaya
V
V
Erk
O
O
Oztürk
S
S
Karan
M A
MA
Salmayenli
N
N
Taşçioğlu
C
C
Güler
K
K
D015415:Biomarkers / Q000097:blood; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis*; D009211:Myoglobin / Q000097:blood*; D011237:Predictive Value of Tests; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D020107:Troponin T / Q000097:blood*; D014421:Turkey
D015415:Biomarkers; D009211:Myoglobin; D020107:Troponin T; D003402:Creatine Kinase