title: Cardiac troponin levels following monitored epileptic seizures.
abstract: Cardiac arrhythmia associated with myocardial injury is a proposed mechanism for sudden unexplained death in epilepsy. The authors measured serial cardiac troponin levels in 11 patients after monitored seizures. Using highly sensitive assays and criteria, no troponin elevations were seen, indicating that myocardial injury does not occur during uncomplicated seizures. An elevation in postictal troponin elevations should suggest the presence of cardiac injury secondary to neurocardiogenic mechanisms or primary cardiac factors, prompting further evaluation.
authors.affiliation: Department of Neurology, Mayo Clinic Rochester, MN 55905, USA.
authors.forename: B K
authors.initials: BK
authors.lastname: Woodruff
authors.forename: J W
authors.initials: JW
authors.lastname: Britton
authors.forename: S
authors.initials: S
authors.lastname: Tigaran
authors.forename: G D
authors.initials: GD
authors.lastname: Cascino
authors.forename: M F
authors.initials: MF
authors.lastname: Burritt
authors.forename: J P
authors.initials: JP
authors.lastname: McConnell
authors.forename: J
authors.initials: J
authors.lastname: Ravkilde
authors.forename: H
authors.initials: H
authors.lastname: Molgaard
authors.forename: F
authors.initials: F
authors.lastname: Andreasen
authors.forename: M
authors.initials: M
authors.lastname: Dam
authors.forename: A S
authors.initials: AS
authors.lastname: Jaffe
mesh_terms: D000328:Adult; D015415:Biomarkers; D009202:Cardiomyopathies / Q000097:blood / Q000209:etiology*; D015331:Cohort Studies; D016757:Death, Sudden, Cardiac / Q000209:etiology; D004562:Electrocardiography; D004827:Epilepsy / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020107:Troponin T / Q000097:blood*
chemical_list: D015415:Biomarkers; D020107:Troponin T