title: Hypercalcaemia associated with a retroperitoneal apocrine gland adenocarcinoma in a dog.
abstract: A seven-year-old, entire female golden retriever was presented with a history of polyuria/polydipsia and progressive dysuria. Clinical examination, radiography and ultrasonography demonstrated urinary retention due to a large soft tissue mass in the retroperitoneal space. Laboratory findings revealed paraneoplastic hypercalcaemia. Fine-needle aspiration cytology of the mass suggested an epithelial tumour, resembling an apocrine gland carcinoma of the anal sac. Following euthanasia and necropsy, the histopathological diagnosis of the retroperitoneal mass was apocrine gland adenocarcinoma. Despite ante- and postmortem examination, no perineal or anal sac tumour was found. The retroperitoneal tumour in this case could be a very large lymph node metastasis from an occult primary apocrine carcinoma of the anal sacs, or it could represent the first case of an ectopic apocrine gland carcinoma of the retroperitoneal space in a dog.
authors.affiliation: Pronto Soccorso Veterinario, Via Defendente 29/A, 26900 Lodi, Italy.
authors.forename: W
authors.initials: W
authors.lastname: Bertazzolo
authors.forename: S
authors.initials: S
authors.lastname: Comazzi
authors.forename: P
authors.initials: P
authors.lastname: Roccabianca
authors.forename: M
authors.initials: M
authors.lastname: Caniatti
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D001050:Apocrine Glands; D001344:Autopsy / Q000662:veterinary; D001774:Blood Chemical Analysis / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000209:etiology / Q000662:veterinary*; D011859:Radiography; D012186:Retroperitoneal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D014463:Ultrasonography