title: [Prediction of the effectiveness of preoperative preparation of patients with fibro-cavernous pulmonary tuberculosis].
abstract: Sixty-three patients with fibrocavernous pulmonary tuberculosis were examined before and 1 month after preoperative therapy with antituberculosis agents. The time course of changes in the clinical and X-ray characteristics of the severity of the disease were compared with the alterations of different biochemical indices, including acute-phase proteins, proteolysis inhibitors, intoxication severity. It was demonstrated that improvement of clinical and X-ray characteristics of the severity of a process after preoperative preparation could be predicted with an accuracy of 83% from the baseline serum concentrations of albumin and ceruloplasmin. The accuracy of prediction does not increase when the levels of protease inhibitors, C-reactive protein, adenosine deaminase, medium-weight molecules are simultaneously studied. The likelihood of the clinical and X-ray characteristics becoming better is higher with enhanced ceruloplasmin activity and decreased albumin levels.
authors.forename: O T
authors.initials: OT
authors.lastname: Titarenko
authors.forename: D S
authors.initials: DS
authors.lastname: Esmedliaeva
authors.forename: M E
authors.initials: ME
authors.lastname: D'iakova
authors.forename: A O
authors.initials: AO
authors.lastname: Avetisian
authors.forename: T B
authors.initials: TB
authors.lastname: Riasnianskaia
authors.forename: T L
authors.initials: TL
authors.lastname: Perova
mesh_terms: D000243:Adenosine Deaminase / Q000097:blood; D000328:Adult; D000418:Albumins / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D011300:Preoperative Care; D011446:Prospective Studies; D011658:Pulmonary Fibrosis / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000150:complications / Q000601:surgery*
chemical_list: D000418:Albumins; D002097:C-Reactive Protein; D000243:Adenosine Deaminase