title: [Gene frequencies and heterozygosity of the AB0 and RH blood group alleles in the populations of two cities of the Donetsk region, Ukraine].
abstract: The frequencies of the AB0 and RH blood group alleles and heterozygosity indices were determined for the populations of two large industrial cities of Gorlovka and Mariupol. In the population of Gorlovka the gene frequencies were as follows: AB0*0 = 0.576, AB0*A = 0.266, AB0*B = 0.158, and RH*D = 0.592, in Mariupol the frequencies were AB0*0 = 0.584, AB0*A = 0.265, AB0*B = 0.151, and RH*D = 0.604. In Gorlovka the heterozygosity indices in respect to the AB0 and RH alleles were 0.572 and 0.483, respectively; in Mariupol, 0.566 and 0.478, respectively. There were no statistically significant differences between the two populations in respect to the genetic markers analyzed. However, the heterozygosity values obtained were more similar to the corresponding estimates for some populations of Russia, than for the total population of the Ukraine.
authors.affiliation: Gorky State Medical University, Donetsk, 83003 Ukraine.
authors.forename: V N
authors.initials: VN
authors.lastname: Mukhin
authors.forename: D G
authors.initials: DG
authors.lastname: Chinakh
authors.forename: A V
authors.initials: AV
authors.lastname: Avdeev
authors.forename: V V
authors.initials: VV
authors.lastname: Kuleba
authors.forename: M V
authors.initials: MV
authors.lastname: Afanas'ev
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D005787:Gene Frequency / Q000235:genetics*; D005819:Genetic Markers; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D012204:Rh-Hr Blood-Group System / Q000235:genetics*; D014455:Ukraine; D014505:Urban Population
chemical_list: D000017:ABO Blood-Group System; D005819:Genetic Markers; D012204:Rh-Hr Blood-Group System