Weight gain in first-episode psychosis.
OBJECTIVE
To examine the extent of weight gain in the first year of treatment in an early psychosis program.


METHODS
Subjects were 114 individuals who had experienced a first episode of psychosis and had completed 1 year in a comprehensive first-episode program. Weight and body mass index were calculated on entry to the program and at 6 and 12 months. Most of the subjects were all being prescribed second-generation antipsychotics.


RESULTS
Significant increases in mean weight were observed in these young individuals over the course of the first year of treatment.


CONCLUSIONS
If we are to work toward optimum treatment for first-episode subjects then potential weight gain needs to be addressed at the beginning of treatment and monitored during treatment.
Addington
Jean
J
Department of Psychiatry, University of Toronto, Toronto, Onatrio. jean_addington@camh.net
Mansley
Chrystal
C
Addington
Donald
D
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009765:Obesity / Q000453:epidemiology*; D011618:Psychotic Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D013997:Time Factors; D015430:Weight Gain
D014150:Antipsychotic Agents