Distribution of HLA-C alleles determined by PCR-SSP in the population of Lower Silesia.
We typed 100 unrelated, healthy Poles from the region of Lower Silesia for HLA-C using low-resolution polymerase chain reaction sequence-specific primers (PCR-SSP) and compared the observed allele frequencies with data published for other human populations. Poles appeared to be most similar to the Germans and English more distant from the French, Catalans and Basques and most dissimilar to non-Caucasians from Equatorial Guinea and Japan. It would be interesting to HLA-C-type other Slavic and non-Slavic peoples from Middle and Eastern Europe for comparison.
Prussak
Magdalena
M
Laboratory of Immunogenetics, Department of Clinical Immunology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Mańczak
Maria
M
Pochroń
Bogusława
B
Nowak
Izabela
I
Kuśnierczyk
Piotr
P
D000483:Alleles; D017931:DNA Primers / Q000235:genetics; D005787:Gene Frequency; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D011044:Poland; D016133:Polymerase Chain Reaction
D017931:DNA Primers; D015236:HLA-C Antigens