Nitric oxide modulates the inhibitory effect of cannabinoids on the immunological activation of guinea pig mast cells.
Vannacci
A
A
Department of Preclinical and Clinical Pharmacology, University of Florence, Viale G. Pieraccini 6, I-50139, Florence, Italy. alfredo.vannacci@unifi.it
Passani
M B
MB
Pierpaoli
S
S
Giannini
L
L
Mannaioni
P F
PF
Masini
E
E
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology; D002186:Cannabinoids / Q000494:pharmacology*; D063388:Endocannabinoids; D005989:Glycerides / Q000494:pharmacology; D006168:Guinea Pigs; D006636:Histamine Release / Q000187:drug effects; D066298:In Vitro Techniques; D008407:Mast Cells / Q000187:drug effects / Q000276:immunology*; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D009569:Nitric Oxide / Q000096:biosynthesis / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D010047:Ovalbumin / Q000276:immunology; D043885:Receptor, Cannabinoid, CB2 / Q000378:metabolism
D000276:Adjuvants, Immunologic; D001095:Arachidonic Acids; D002186:Cannabinoids; D063388:Endocannabinoids; D005989:Glycerides; D043885:Receptor, Cannabinoid, CB2; D009569:Nitric Oxide; C094503:glyceryl 2-arachidonate; D010047:Ovalbumin; D019001:Nitric Oxide Synthase; D019331:NG-Nitroarginine Methyl Ester