Stem cells and cardiac disorders: an appraisal.
The use of stem cells has proved to be an important tool in investigating the events of early cardiac development, differentiation, and morphogenesis. In addition, stem cell transplantation in the treatment of certain cardiac disorders has shown early promise. We have attempted to present a balanced review of both basic studies and clinical-therapeutic potential of stem cells transplantation in the damaged heart.
Goldenthal
Michael J
MJ
The Molecular Cardiology and Neuromuscular Institute, 75 Raritan Avenue, Highland Park, NJ 08904, USA.
Marín-García
José
J
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology; D002454:Cell Differentiation / Q000502:physiology; D002460:Cell Line; D004730:Endothelium, Vascular / Q000166:cytology; D006331:Heart Diseases / Q000628:therapy*; D006801:Humans; D028361:Mitochondrial Diseases / Q000601:surgery; D032386:Myoblasts, Cardiac / Q000502:physiology; D032448:Myoblasts, Skeletal / Q000166:cytology; D039904:Pluripotent Stem Cells / Q000166:cytology; D033581:Stem Cell Transplantation / Q000379:methods*