New concept in the pathogenesis of cardiovascular disease.
The advent of HAART has increased the lifespan of and enhanced the quality of life for patients with HIV infection. However, the gains achieved with HAART may be lost if all known risk factors for cardiovascular disease are not effectively managed in this population. This article reviews recent information on the contributions of insulin resistance, infection and inflammation, and psychiatric and psychological conditions associated with cardiovascular risk. It also summarizes available data on treatments of these risk factors.
Albu
Jeanine B
JB
Columbia University College of Physicians & Surgeons, New York, USA.
Rozanski
Alan
A
Epstein
Stephen E
SE
D023241:Antiretroviral Therapy, Highly Active; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D007333:Insulin Resistance; D009765:Obesity / Q000150:complications / Q000628:therapy; D011788:Quality of Life; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications