title: Treatments for depression: wisdom imparted from treatments discarded.
abstract: Many different forms of treatment have been used with patients suffering from depression. It can be difficult to examine current treatments and anticipate problems, mistakes, and limitations. However, a historical perspective allows an appreciation of the strengths and limitations of older treatments, and sheds light on current strategies. A variety of effective treatments have been discarded and forgotten. Important lessons can be learned by reviewing the history of treatments for depression. Many treatment strategies were based on accidental discovery, but nonetheless were found effective in reducing the symptoms of depression. Both case examples and group studies have documented the effectiveness of these older treatments. A review of discarded treatments reveals how a biological model can be limited in its ability to produce a lasting cure. Caution and skepticism are encouraged when innovative treatments are proposed.
authors.affiliation: Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106-7123, USA. overholser@po.cwru.edu
authors.forename: James C
authors.initials: JC
authors.lastname: Overholser
mesh_terms: D003866:Depressive Disorder / Q000266:history* / Q000628:therapy; D004565:Electroconvulsive Therapy / Q000266:history / Q000379:methods; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D049690:History, Ancient; D006875:Hydrotherapy / Q000266:history / Q000379:methods; D011612:Psychosurgery / Q000266:history; D012890:Sleep