Radiation safety issues with high activities of liquid I-125: techniques and experience.
The handling of a liquid radioactive source is a procedure that is uncommon for the average clinical medical physicist. A newly approved treatment device utilizes high activities of liquid I-125 solution as the source of radiation. The radiation safety issues and our experience utilizing high activity liquid I-125 sources are presented. To date we have treated 22 patients with infused activities ranging up to 26.8 GBq (724 mCi). The careful manipulation of such solutions is important to maintain a safe environment for the patients and the involved medical staff.
deGuzman
A F
AF
Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, USA. deguzman@wfubmc.edu
Kearns
W T
WT
Shaw
E
E
Tatter
S
S
Stieber
V
V
Yates
C
C
Amadeo
H
H
Hinson
W H
WH
D001557:Benzenesulfonates / Q000737:chemistry / Q000627:therapeutic use / Q000652:urine; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods / Q000639:trends*; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000601:surgery; D002404:Catheterization / Q000295:instrumentation / Q000379:methods; D004869:Equipment Safety; D006801:Humans; D007457:Iodine Radioisotopes / Q000737:chemistry* / Q000627:therapeutic use / Q000652:urine; D016272:Occupational Health; D011879:Radiotherapy Dosage; D012996:Solutions / Q000737:chemistry / Q000627:therapeutic use; D013997:Time Factors
D001557:Benzenesulfonates; D007457:Iodine Radioisotopes; D012996:Solutions; C421459:iotrex