[Diagnosis and treatment of lung aspergillosis after liver transplantation].
OBJECTIVE
To assess the diagnosis and treatment of invasive lung aspergillosis after liver transplantation.


METHODS
Routine sputum culture was performed. Itraconazole and fluconazole were used to prevent fungal infection prophylactically. Amphyotericin B was only used on aspergillosis. In 54 patients receiving, liver transplantation, 3 patients with lung aspergillosis were reviewed.


RESULTS
Of the 3 patients 2 died and 1 recovered.


CONCLUSIONS
Over-immunosuppression is a main risk factor for aspergillosis. Amphotericin B is still the best choice for the treatment of aspergillosis and its gradual, interrupted, low concentration administration, cooperated with itraconazole can ease the side effects.
Lin
Qi-yuan
QY
Department of Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Zhao
Yong-heng
YH
Yan
Lü-nan
LN
Huang
An-hua
AH
Li
Bo
B
Lu
Shi-chun
SC
Zeng
Yong
Y
Wen
Tian-fu
TF
Zhao
Ji-chun
JC
Cheng
Nan-sheng
NS
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged