In vivo assays for COX-2.
Chan
Chi-Chung
CC
Merck Frosst Centre for Therapeutic Research, Quebec, Canada.
D000818:Animals; D001169:Arthritis, Experimental / Q000201:enzymology; D002351:Carrageenan / Q000633:toxicity; D002712:Chlorides / Q000032:analysis; D017608:Chromium Compounds / Q000032:analysis; D002860:Chromium Radioisotopes / Q000493:pharmacokinetics; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D004487:Edema / Q000139:chemically induced / Q000378:metabolism; D004731:Endotoxins / Q000633:toxicity; D005243:Feces / Q000737:chemistry; D005260:Female; D005334:Fever / Q000188:drug therapy / Q000201:enzymology; D005528:Foot; D006930:Hyperalgesia / Q000188:drug therapy / Q000201:enzymology; D007249:Inflammation / Q000188:drug therapy / Q000201:enzymology; D007527:Isoenzymes / Q000032:analysis*; D008297:Male; D023421:Models, Animal; D010539:Permeability; D011451:Prostaglandin-Endoperoxide Synthases / Q000032:analysis*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D051381:Rats; D011917:Rats, Inbred Lew; D017207:Rats, Sprague-Dawley; D012453:Saimiri
D002712:Chlorides; D017608:Chromium Compounds; D002860:Chromium Radioisotopes; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D004731:Endotoxins; D007527:Isoenzymes; D019275:Radiopharmaceuticals; D002351:Carrageenan; C017133:chromous chloride; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases