title: Ten-year follow-up in a maxillary sinus augmentation using anorganic bovine bone (Bio-Oss). A case report with histomorphometric evaluation.
abstract: Several bone grafting materials have been used in sinus augmentation procedures. Bio-Oss (deproteinized and sterilized bovine bone) has shown to have osteoconductive properties and no inflammatory or adverse responses have been published. In spite of these successful results, histologic data regarding bone augmentation using Bio-Oss in humans is scarce. The purpose of this study was to analyse the amount of Bio-Oss ossification in a case of maxillary sinus augmentation, recording and comparing histomorphometric data 8 months, 2 and 10 years after surgery. This long-term histologic evaluation of retrieved specimens has been performed, comparing histomorfometric measures at different times. Eight months after surgery we observed in 20 different thin sections of the specimen a mean amount of bone tissue (including medullar spaces) of 29.8% (and 70.2% of Bio-Oss) +/- 2.6. At 2 years the bone tissue increased to 69.7% + 2.7 and 10 years after surgery it was 86.7% +/- 2.8. The comparison of the means for each time has shown a highly significant increasing trend in bone formation associated with Bio-oss resorption: at 8 months, 2 and 10 years.
authors.affiliation: IRCCS Pol. S. Matteo - UDA Periodontology and Maxdlofacial Surgery, University of Pavia, Italy. stefano.sartori@unipv.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Sartori
authors.forename: M
authors.initials: M
authors.lastname: Silvestri
authors.forename: F
authors.initials: F
authors.lastname: Forni
authors.forename: A
authors.initials: A
authors.lastname: Icaro Cornaglia
authors.forename: P
authors.initials: P
authors.lastname: Tesei
authors.forename: V
authors.initials: V
authors.lastname: Cattaneo
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D001857:Bone Matrix / Q000473:pathology / Q000637:transplantation*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002417:Cattle; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery*; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use*; D010012:Osteogenesis / Q000502:physiology
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D008903:Minerals