title: Atomic force microscopy as a tool for biomedical and biotechnological studies.
abstract: This work presents different applications in progress with the aid of the atomic force microscopy (AFM) technique for biomedical and biotechnological applications, comprising both the acquisition of three-dimensional images and spectroscopic force measurements, in the following systems: first, low-density lipoprotein (LDL)-glycosaminoglycans; second, lectins-polysaccharides; third, mycobacterium leprae cellular wall and Vesicular Stomatites Virus (VSV) with fibronectin laminin, and lipidic membranes; fourth, DNA-complex; and fifth, actin, as well as the development of surface functionalizing protocols and image restoration by means of mathematical techniques.
authors.affiliation: Instituto de Biofísica Carlos Chagas Filho, CCS, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Janeiro, RJ, Brazil. gcidade@biof.ufrj.br
authors.forename: Geraldo Antônio Guerrera
authors.initials: GA
authors.lastname: Cidade
authors.forename: Lilian Terezinha
authors.initials: LT
authors.lastname: Costa
authors.forename: Gilberto
authors.initials: G
authors.lastname: Weissmüller
authors.forename: Antônio José
authors.initials: AJ
authors.lastname: da Silva Neto
authors.forename: Nilson Costa
authors.initials: NC
authors.lastname: Roberty
authors.forename: Marta Bueno
authors.initials: MB
authors.lastname: de Moraes
authors.forename: Gilza Maria Piedade
authors.initials: GM
authors.lastname: Prazeres
authors.forename: Carlos Eduardo Marques
authors.initials: CE
authors.lastname: Hill
authors.forename: Simone Jesus Machado
authors.initials: SJ
authors.lastname: Ribeiro
authors.forename: Gutierre Guarino Bastos
authors.initials: GG
authors.lastname: de Souza
authors.forename: Luciano
authors.initials: L
authors.lastname: da Silva Pinto Teixeira
authors.forename: Marlos
authors.initials: M
authors.lastname: da Costa Monçores
authors.forename: Paulo Mascarello
authors.initials: PM
authors.lastname: Bisch
mesh_terms: D020811:Biomedical Technology; D003585:Cell Biology / Q000295:instrumentation; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D021621:Imaging, Three-Dimensional; D018625:Microscopy, Atomic Force / Q000379:methods*; D013499:Surface Properties