Colorectal cancer screening for the natural population of Beijing with sequential fecal occult blood test: a multicenter study.
OBJECTIVE
To assess the prevalence of colorectal cancer (CRC) in Beijing and the reliability of the sequential fecal occult blood test (SFOBT) for CRC screening.


METHODS
Of the natural population (48 100 persons) in several Beijing communities, we screened 26 827 persons with age over 30 using the SFOBT screening program, Guaiacum Fecal Occult Blood Test (GFOBT), Immuno Fecal Occult Blood Test (IFOBT), and colonoscopies.


RESULTS
The screening rate of the population was 74%. The positive rate of SFOBT was 5.6%. The prevalence of CRC in the entire population of Beijing was therefore calculated to be 36.57/10(5). Of 12 CRC detected patients, 4 cases were in stage Dukes A (33.33%), 7 cases in stage Dukes B (58.33%), only 1 case (8.34%) in stage Dukes C.


CONCLUSIONS
The prevalence of CRC in Beijing is one of the highest in China. Individuals at high risk for CRC or those over 50 years of age should be considered as primary candidates for screening. SFOBT screening is a cost-effective and reliable method for early detection of CRC.
Li
Shirong
S
Department of Gastroenterology, General Hospital of Beijing Military Region, Beijing 100700, China. Lishirong2000@yahoo.com.cn
Nie
Zhaohua
Z
Li
Nan
N
Li
Junxiang
J
Zhang
Ping
P
Yang
Zhaoxu
Z
Mu
Shankun
S
Du
Yaping
Y
Hu
Jichun
J
Yuan
Shenyuan
S
Qu
Hanting
H
Zhang
Taichang
T
Wang
Shixin
S
Dong
Enyu
E
Qi
Defang
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009780:Occult Blood