Himeradine A, a novel C27N3-type alkaloid from Lycopodium chinense.
A novel C(27)N(3)-type Lycopodium alkaloid consisting of a fastigiatine-type skeleton (C(16)N(2)) and a quinolizidine moiety (C(11)N), himeradine A (1), has been isolated from the club moss Lycopodium chinense, and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data.
Morita
Hiroshi
H
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Hirasawa
Yusuke
Y
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D004354:Drug Screening Assays, Antitumor; D020128:Inhibitory Concentration 50; D032502:Lycopodium / Q000737:chemistry*; D008223:Lymphoma; D051379:Mice; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000470:Alkaloids; D011807:Quinolizines; C480481:himeradine A