title: [Surgical management of metastatic disease of long bone].
abstract: OBJECTIVE
  To improve the life quality of cancer patients with metastasis to long bone and to select suitable surgical treatment.
  
  
  METHODS
  Fifty two patients with metastasis 27 men and 25 women, were treated from 1990 to 1999. Their average age was 56.8 years (33 - 74). In 16 patients with multiple lesions, underwent surgery at bone shaft (29 patients) and bone epiphysis (26). Thirty patients were treated for pathologic fracture and the rest for impending fracture. Operations included limb-salvage (51 patients) and amputation (4) Limb salvage consisted of intralesional curettage (3 patients), intramedullary nailing reconstruction (29), endoprosthesis (18), and temporary spacer (1). 21 patients accepted postoperative chemotherapy or radiotherapy.
  
  
  RESULTS
  Follow-up of 52 patients for a mean of 28.2 months (2 - 122 months) showed pain relief (41 patients), (75%) and full or part weight-bearing stability (36) 69%. Local tumor recurrence occurred in 11 patients.
  
  
  CONCLUSIONS
  Surgical treatment can effectively improve the life quality of patients with metastasis to long bone. The metastatic lesions should be resected with wide or radical margin for the patients with kidney, breast, prostate and thyroid cancer.
authors.affiliation: Department of Orthopaedic Oncology, Jishuitan Hospital, Beijing 100035, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: You-bo
authors.initials: YB
authors.lastname: Cai
authors.forename: Xiao-hui
authors.initials: XH
authors.lastname: Niu
authors.forename: Lin
authors.initials: L
authors.lastname: Hao
authors.forename: Yi
authors.initials: Y
authors.lastname: Ding
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome