[Value of condensation and rarefaction click evoked action potential latency difference in the diagnosis of Meniere's disease].
OBJECTIVE
To study the value of condensation and rarefaction clicks evoked action potential (AP) latency difference (LD) in diagnosis of Meniere's disease.


METHODS
AP was recorded with ECochG in controls (50 ears) and patients with Meniere's disease(90 ears) and sensorineural hearing loss(SNHL) of other origins(60 ears). LD was calculated and analyzed.


RESULTS
LD in patients with Meniere's disease was (0.30 +/- 0.15) ms, which was significantly larger than that of controls(0.18 +/- 0.07) ms and of patients with SNHL of other origins(0.20 +/- 0.10) ms (P < 0.01). In the group of Meniere's disease, LD in patients with the mild and moderate hearing impairment was larger than those with severe hearing loss(P < 0.01) and LD in patients with low tone or high tone auditory sensation curve was larger than those with flat auditory sensation curve(P < 0.01). Positive rate was 4/60(6.7%) in other SNHL patients and 58/90(64.0%) in Meniere's disease group respectively.


CONCLUSIONS
The increase in condensation and rarefaction click evoked AP latency difference can be an objective parameter in diagnosis of Meniere's disease.
Wang
Z
Z
Department of Otorhinolaryngology, PLA 266th Hospital, Hebei, Chengde 067000, China.
Shao
X
X
Yan
W
W
Lin
H
H
D000200:Action Potentials / Q000502:physiology; D000293:Adolescent; D000328:Adult; D001300:Audiometry, Evoked Response / Q000379:methods*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged