title: [Protective effect of daizein on apoptosis cells of nasal mucosas in ovariectomized rats].
abstract: OBJECTIVE
  To study the protective effect of daizein on apoptosis cells of atrophic nasal mucosas in ovariectomized rats.
  
  
  METHODS
  Sixty rats were divided into four groups as contrary, ovariectomized, ovariectomized + nylestriol (O + N) and ovariectomized + daizein (O + D), each with 15 rats. Earlier apotosis cells of nasal mucosas taken from nasal septum were measured with flow cytometry.
  
  
  RESULTS
  Compared with contrary group, the number of apoptosis cells of mucosas increased after being ovariectomized, the number of apoptosis cells of mucosas in O + N and O + D groups didn't change.
  
  
  CONCLUSIONS
  Estrogen replacement and daizein might have effects on protecting cells of mucosas from lacking of estrogen by decreasing apoptosis cells in ovariectomized rats.
authors.affiliation: Department of Otorhinolaryngology, First People's Hospital of Yunnan Province, Kunming 650001, China. qibenming@21cn.com
authors.forename: Ben-ming
authors.initials: BM
authors.lastname: Qi
authors.forename: Xing-hua
authors.initials: XH
authors.lastname: Tian
authors.forename: Ji-bao
authors.initials: JB
authors.lastname: Wang
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D001284:Atrophy; D004847:Epithelial Cells / Q000473:pathology*; D005260:Female; D007529:Isoflavones / Q000494:pharmacology*; D009297:Nasal Mucosa / Q000473:pathology*; D010052:Ovariectomy; D011800:Quinestrol / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D007529:Isoflavones; C004742:daidzein; C010722:nylestriol; D011800:Quinestrol