title: Quantitative histochemical assessment of oxidative metabolism in the subfornical organ after partial aortic ligature in rats.
abstract: Circumventricular organs are considered to be involved in hydromineral homeostatic responses. In this study we used quantitative histochemistry of cytochrome oxidase to evaluate the oxidative metabolic activity of the subfornical organ of rats with a partial aortic occlusion. These rats showed a significant increase in water intake from the second day after the ligature, while natriophilia was already significant on the first day. Greater levels of cytochrome oxidase activity were found in subfornical organs of partial aortic ligated rats when compared with control, providing further evidence for the involvement of this circumventricular structure in fluid homeostasis at least in this hyperdipsic, hypernatriophilic, hyperreninemic and hypertensive experimental model.
authors.affiliation: Departamento de Biología Funcional (Area de Fisiología), Facultad de Medicina, Universidad de Oviedo, C/ Julian Claveria 6, E-33006, Oviedo, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Alonso-Magdalena
authors.forename: J
authors.initials: J
authors.lastname: Arguelles
authors.forename: N
authors.initials: N
authors.lastname: Conejo Jimenez
authors.forename: H
authors.initials: H
authors.lastname: Gonzalez-Pardo
authors.forename: C
authors.initials: C
authors.lastname: Perillan
authors.forename: M
authors.initials: M
authors.lastname: Costales
authors.forename: M
authors.initials: M
authors.lastname: Vijande
mesh_terms: D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery*; D001066:Appetite; D004327:Drinking Behavior / Q000502:physiology; D003576:Electron Transport Complex IV / Q000378:metabolism*; D007150:Immunohistochemistry; D008026:Ligation; D008297:Male; D010085:Oxidative Phosphorylation; D051381:Rats; D012965:Sodium Chloride; D013356:Subfornical Organ / Q000378:metabolism*; D014882:Water-Electrolyte Balance / Q000502:physiology*
chemical_list: D012965:Sodium Chloride; D003576:Electron Transport Complex IV