Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging.
Imai
S
S
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Johnson
F B
FB
Marciniak
R A
RA
McVey
M
M
Park
P U
PU
Guarente
L
L
D000375:Aging / Q000235:genetics / Q000502:physiology*; D000818:Animals; D002843:Chromatin / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D020868:Gene Silencing; D006655:Histone Deacetylases / Q000378:metabolism; D006801:Humans; D037761:Sirtuins / Q000235:genetics* / Q000378:metabolism*
D002843:Chromatin; D037761:Sirtuins; D006655:Histone Deacetylases