title: Easy access to novel substituted 6-aminoimidazo[1,2-a]pyridines using palladium- and copper-catalyzed aminations.
abstract: Convenient and efficient methods for the preparation of novel 6-aminoimidazo[1,2-a]pyridine derivatives are reported that utilized palladium- or copper-catalyzed methodology. The crystal structure for 6-N-methylanilinoimidazo[1,2-a]pyridine 10 is also described.
authors.affiliation: EA 3247, Laboratoire de Chimie Thérapeutique, Laboratoire de Chimie Physique, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Enguehard
authors.forename: Hassan
authors.initials: H
authors.lastname: Allouchi
authors.forename: Alain
authors.initials: A
authors.lastname: Gueiffier
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Buchwald
mesh_terms: D000586:Amination; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis*
chemical_list: D007093:Imidazoles; D007202:Indicators and Reagents; D011725:Pyridines; D010165:Palladium; D003300:Copper