title: [Effects of bu yang huan wu decoction on astrocytes after cerebral ischemia and reperfusion].
abstract: OBJECTIVE
  To study the effects of Bu Yang Huan Wu Decoction on astrocytes after cerebral ischemia and reperfusion.
  
  
  METHODS
  Cerebral ischemia model in gerbils was produced by ligating bilateral common carotid artery. The dynamic expressin of GFAP were determined by immunochemistry after cerebyal ischemia for 15 min followed by reperfusion for 24 hours and 48 hours.
  
  
  RESULTS
  GFAP positive reactions reached a peak after cerebral ischemia for 15 min followed by reperfusion for 24 hours. Bu Yang Huan Wu Decoction decreased the expression. GFAP positive reactions decreased after cerebral ischemia for 15 min followed by reperfusion for 48 hours, Bu Yang Huan Wu Decoction increased the expression.
  
  
  CONCLUSIONS
  The regulation of Bu Yang Huan Wu Decoction on astrocytes after cerebral ischemia and reperfusion may be related to repairing process after cerebral ischemia.
authors.affiliation: Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Lai
authors.forename: Sha-yan
authors.initials: SY
authors.lastname: Wang
authors.forename: Xiao-yin
authors.initials: XY
authors.lastname: Geng
authors.forename: Chang-qing
authors.initials: CQ
authors.lastname: Deng
authors.forename: Ruan-zhang
authors.initials: RZ
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000187:drug effects*; D002545:Brain Ischemia / Q000150:complications; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism; D008297:Male; D010946:Plants, Medicinal / Q000737:chemistry; D015427:Reperfusion Injury / Q000209:etiology / Q000378:metabolism / Q000473:pathology*
chemical_list: D004365:Drugs, Chinese Herbal; D005904:Glial Fibrillary Acidic Protein; C460102:buyang huanwu