Tacrolimus in renal transplantation. A review of recent data.
This overview will cover the main development of the use of Tacrolimus in organ transplantation. It summarizes the large amount of data which have recently appeared in the literature, especially in comparison with Cyclosporine, with recent controlled conversion experience, combination therapies, withdrawal of corticosteroids, the use of Tacrolimus in monotherapy and in paediatric renal transplant patients. Finally cardiovascular risk factors are discussed in the light of the other main risk factors in this particular population of transplant patients.
Charpentier
B
B
Service de Néphrologie, CHU de Bicetre, Le Kremlin Bicetre, France. bernard.charperntier@bct.ap-hop-paris.fr
D002318:Cardiovascular Diseases / Q000209:etiology; D002648:Child; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects; D012307:Risk Factors; D016559:Tacrolimus / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D016559:Tacrolimus