title: [Changes of dehydroandrographolide's contents of andrographis tablet in the process of production].
abstract: OBJECTIVE
  To recognize changes in the contents of ingredients of Andrographis Tablet in the process of production.
  
  
  METHODS
  Adopting TLCS, TLC, HPLC to detect effective contents of ingredients which are produced in every stage of process of Andrographis Table's production.
  
  
  RESULTS
  Handling with the fresh Herba Andrographis according to current pharmacopeoia's technology, it showed that only dehyandrographolide can be detected. It indicated that the main factor that leads to chemical change is the heating process in the process of production.
  
  
  CONCLUSIONS
  Avoiding heating treatment or reducing heating treatment time is the main factor to protect the effective ingredients.
authors.affiliation: Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, Guangdong, China. helloxiaodan@yahoo.com
authors.forename: Xiao-dan
authors.initials: XD
authors.lastname: Huang
authors.forename: Zi-ren
authors.initials: ZR
authors.lastname: Su
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Lai
authors.forename: Shu-hai
authors.initials: SH
authors.lastname: Lin
authors.forename: Xiao-bing
authors.initials: XB
authors.lastname: Dong
authors.forename: Zhong-qiu
authors.initials: ZQ
authors.lastname: Liu
authors.forename: Pei-shan
authors.initials: PS
authors.lastname: Xie
mesh_terms: D035685:Andrographis / Q000737:chemistry*; D004224:Diterpenes / Q000032:analysis*; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D006358:Hot Temperature; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013607:Tablets; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D013607:Tablets; C030419:andrographolide; C478098:dehydroandrographolide