Telomere structure, function and maintenance in Arabidopsis.
The stability of eukaryotic genomes is provided in part by the integrity of telomeres, the nucleoprotein caps on the ends of chromosome. Recent studies reveal that proper telomere architecture is required for long-term proliferation capacity. Here we describe molecular mechanisms that protect and maintain chromosome ends and discuss why Arabidopsis is emerging as a powerful new model for elucidating fundamental aspects of telomere biology.
Riha
Karel
K
Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, USA.
Shippen
Dorothy E
DE
D017360:Arabidopsis / Q000166:cytology* / Q000201:enzymology / Q000235:genetics*; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D004260:DNA Repair; D018744:DNA, Plant / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins; D019098:Telomerase / Q000378:metabolism; D016615:Telomere / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*
D002868:Chromosomal Proteins, Non-Histone; D018744:DNA, Plant; D004268:DNA-Binding Proteins; D019098:Telomerase