The ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates.
The biocatalytic potential of Bipolaris sorokiniana was investigated in its ability to modify the monoterpene geraniol and the sesquiterpene alpha-bisabolol as exogenous substrates, using phosphate buffer as reaction medium. The cultures showed a promising oxidative profile, with conversion of geraniol to 6-methyl-5-hepten-2-one (74.9% yield) in a 5-day incubation and alpha-bisabolol to bisabolol oxide B (84.2% yield), in a 7-day incubation.
Limberger
R P
RP
Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto Alegre, Rio Grande do Sul, Brazil.
Ferreira
L
L
Castilhos
T
T
Aleixo
A M
AM
Petersen
R Z
RZ
Germani
J C
JC
Zuanazzi
J A
JA
Fett-Neto
A G
AG
Henriques
A T
AT
D000080462:Acyclic Monoterpenes; D001203:Ascomycota / Q000378:metabolism*; D019149:Bioreactors; D001709:Biotechnology; D001711:Biotransformation; D003470:Culture Media; D000081222:Monocyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000378:metabolism*; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism*
D000080462:Acyclic Monoterpenes; D003470:Culture Media; D000081222:Monocyclic Sesquiterpenes; D012717:Sesquiterpenes; D013729:Terpenes; C004497:bisabolol; C007836:geraniol