title: Nonspecific ulcers of the colon.
abstract: Nonspecific colonic ulcers (NSCUs) are rare and potentially life-threatening lesions of unknown etiology; the diagnosis is based on histologic findings showing nonspecific inflammatory changes. The condition's variable symptoms can include nonspecific abdominal discomfort, gastrointestinal bleeding, perforation, and peritonitis. Radiologic imaging can be helpful in locating the lesions, but colonoscopy facilitates early definitive diagnosis and aggressive treatment. The potential of NSCUs to recur is currently unknown, and morbidity rates remain high. Long-term colonoscopic follow-up may improve the prognosis.
authors.affiliation: Dept. of Surgery, University of Missouri-Columbia School of Medicine, One Hospital Drive, Columbia, MO 65212, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Losanoff
authors.forename: B W
authors.initials: BW
authors.lastname: Richman
authors.forename: J R
authors.initials: JR
authors.lastname: Foerst
authors.forename: A D
authors.initials: AD
authors.lastname: Griesemer
authors.forename: G M
authors.initials: GM
authors.lastname: Mundis
authors.forename: J W
authors.initials: JW
authors.lastname: Jones
mesh_terms: D003108:Colonic Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003113:Colonoscopy; D005500:Follow-Up Studies; D006801:Humans; D014057:Tomography, X-Ray Computed; D014456:Ulcer / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery