title: Epiretinal membrane removal in diabetic eyes: comparison of viscodissection with conventional methods of membrane peeling.
abstract: OBJECTIVE
  To compare conventional methods of epiretinal membrane peeling with viscodissection.
  
  
  METHODS
  154 eyes with proliferative diabetic retinopathy (PDR) that underwent pars plana vitrectomy with membrane dissection (89 traditional, 65 viscodissection) were studied retrospectively. Incidence of retinal breaks (RBs), length of time under anaesthesia, postoperative intraocular pressure, retinal reattachment rate, and final visual acuity (VA) were measured.
  
  
  RESULTS
  To compare cases of similar complexity, a "complexity score" was defined. The average complexity score for cases done with and without viscodissection was 4.7 and 3.2, respectively. The mean frequency of RBs in eyes undergoing viscodissection was 0.43 (SD 0.5) v 0.14 (0.35) RBs/eye without viscodissection. In complex cases, the frequency of posterior/peripheral RBs was 0.31 (0.47)/0.13 (0.34) RBs/eye, respectively, with viscodissection v 0.12 (0.33)/0.23 (0.43) RBs/eye without viscodissection. None of these differences were statistically significant. The average preoperative/postoperative VA (logMAR) in the viscodissection cohort was 1.7/1.3 (range 0.3 to >1.9/0.1 to >1.9) v 1.4/1 (range 0.48 to >1.9/0.1 to >1.9) in the non-viscodissection cohort, among eyes with 6 months of follow up. Anaesthesia duration was significantly shorter for cases done without viscodissection (p=0.03), but cases done with viscodissection were significantly more complex than cases done without viscodissection (p<0.0001).
  
  
  CONCLUSIONS
  Viscodissection appears to be a safe and effective alternative technique in eyes with PDR. Owing to the retrospective nature of the study, additional studies are warranted.
authors.affiliation: The Institute of Ophthalmology and Visual Science, UMDNJ-New Jersey Medical School, NJ, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Grigorian
authors.forename: A
authors.initials: A
authors.lastname: Castellarin
authors.forename: R
authors.initials: R
authors.lastname: Fegan
authors.forename: C
authors.initials: C
authors.lastname: Seery
authors.forename: L V
authors.initials: LV
authors.lastname: Del Priore
authors.forename: S
authors.initials: S
authors.lastname: Von Hagen
authors.forename: M A
authors.initials: MA
authors.lastname: Zarbin
mesh_terms: D003930:Diabetic Retinopathy / Q000503:physiopathology / Q000601:surgery*; D004210:Dissection / Q000379:methods; D019773:Epiretinal Membrane / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012163:Retinal Detachment / Q000209:etiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*; D018630:Vitreoretinopathy, Proliferative / Q000503:physiopathology / Q000601:surgery*; D020255:Vitreous Detachment / Q000209:etiology