title: Treatment of toxic epidermal necrolysis in AIDS with intravenous immunoglobulins.
abstract: Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per day for two consecutive days and both experienced a good outcome. Intravenous immunoglobulin potentially lowers the morbidity and mortality of TEN and shortens the duration of the patient's hospitalization.
authors.affiliation: National Skin Centre, Singapore. audreytan@nsc.gov.sg
authors.forename: A
authors.initials: A
authors.lastname: Tan
authors.forename: H H
authors.initials: HH
authors.lastname: Tan
authors.forename: C C
authors.initials: CC
authors.lastname: Lee
authors.forename: S K
authors.initials: SK
authors.lastname: Ng
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013262:Stevens-Johnson Syndrome / Q000209:etiology / Q000473:pathology / Q000628:therapy*
chemical_list: D016756:Immunoglobulins, Intravenous