Photomediated asymmetric synthesis of (-)-cuparene.
Generation of a benzylic quaternary stereocentre via the photomediated cyclisation of a chiral alpha-(aminobutyl)styrene followed by a microwave-assisted Cope elimination has led to a total synthesis of the sesquiterpene (-)-cuparene.
Grainger
Richard S
RS
Department of Chemistry, King's College London, Strand, London, UK WC2R 2LS. richard.grainger@kcl.ac.uk
Patel
Aslam
A
D015394:Molecular Structure; D010777:Photochemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry*
D012717:Sesquiterpenes; C483527:cuparene