title: Toll and Toll-like receptors in Drosophila.
abstract: The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. One exception may be Toll-9, which shares structural and functional similarities with mammalian TLRs.
authors.affiliation: UPR9022 CNRS, 15 rue René Descartes, 67084 Strasbourg Cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Bilak
authors.forename: S
authors.initials: S
authors.lastname: Tauszig-Delamasure
authors.forename: J-L
authors.initials: JL
authors.lastname: Imler
mesh_terms: D000818:Animals; D005075:Biological Evolution; D004330:Drosophila / Q000235:genetics / Q000276:immunology* / Q000382:microbiology*; D029721:Drosophila Proteins; D005658:Fungi / Q000472:pathogenicity; D016678:Genome; D006090:Gram-Negative Bacteria / Q000472:pathogenicity; D006094:Gram-Positive Bacteria / Q000472:pathogenicity; D008562:Membrane Glycoproteins / Q000235:genetics / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology*; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors
chemical_list: D029721:Drosophila Proteins; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors; C495341:tehao protein, Drosophila