title: [Effects of excess caloric fat feeding on the lipid metabolism in Shetland ponies].
abstract: To investigate the influence of overweight and dietary fat supplementation on lipid and insulin glucose metabolism of Shetland ponies, eight Shetland pony geldings were fed a hypercaloric (30 MJ DE/150 kg bwt. and day) fat diet (10% fat as soybean oil) or a carbohydrate control diet for nine months until ponies gained an overweight of 15%. Afterwards oral glucose tolerance tests (oGTT; 5, 6 mmol/kg bwt.) were performed after a 12 hour fast and after a fast which led to an increase of plasma triglyceride concentrations to a threshold of 3 mmol/l (36-65 hrs.). Plasma concentrations of glucose, insulin, triglycerides and non esterified fatty acids (NEFA) were determined for 480 minutes after the glucose load. Ponys having had received the control diet tended to a higher insulin secretion in case of both oGTTs, whereas the glucose tolerance was similar in both groups but lower than in ponies of normal weight. During the oGTTs after fasting leading to the plasma triglyceride threshold, triglyceride concentrations decreased significantly (p < 0.05) faster and stronger in fat fed ponies. Additionally, fat fed pony showed significantly (p < 0.05) lower NEFA levels. The results of this study demonstrate a positive effect of fat feeding on the triglyceride clearance of overweight Shetland ponies.
authors.affiliation: Institut für Physiologische Chemie, Tierärztliche Hochschule Hannover.
authors.forename: R
authors.initials: R
authors.lastname: Dühlmeier
authors.forename: T
authors.initials: T
authors.lastname: Gück
authors.forename: E
authors.initials: E
authors.lastname: Deegen
authors.forename: R
authors.initials: R
authors.lastname: Busche
authors.forename: H P
authors.initials: HP
authors.lastname: Sallmann
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004032:Diet / Q000662:veterinary; D004041:Dietary Fats / Q000008:administration & dosage*; D002149:Energy Intake; D004734:Energy Metabolism; D005215:Fasting / Q000097:blood; D005951:Glucose Tolerance Test / Q000662:veterinary; D006734:Horse Diseases / Q000378:metabolism*; D006736:Horses / Q000097:blood / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000378:metabolism / Q000662:veterinary*; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D004041:Dietary Fats; D007328:Insulin; D008055:Lipids; D014280:Triglycerides