Flavonol and drimane-type sesquiterpene glycosides of Warburgia stuhlmannii leaves.
An investigation of methanolic extract of Warburgia stuhlmannii leaves has led to the isolation of two new drimane-type sesquiterpene glycosides characterized as mukaadial 6-O-beta-D-glucopyranoside, mukaadial 6-O-alpha-L-rhamnopyranoside together with two other novel flavonol glycosides identified as 3',5'-O-dimethylmyricetin 3-O-beta-D-2",3"-diacetylglucopyranoside and 3'-O-methylquercetin 3-O-beta-D-2",3",4"-triacetylglucopyranoside. The known compounds; mukaadial, deacetylugandensolide, quercetin, kaempferol, kaempferol 3-O-alpha-L-rhamnopyranoside, quercetin 3-O-beta-D-glucopyranoside, kaempferol 7-O-beta-D-glucopyranoside, myricetin 3-O-alpha-L-rhamnopyranoside, quercetin 3-O-alpha-L-rhamnopyranoside, quercetin 3-O-sophoroside and isorhamnetin 3-O-beta-D-glucopyranoside were also isolated from the same extract.
Manguro
Lawrence O Arot
LO
Chemistry Department, Nairobi University, PO Box 30197, Nairobi, Kenya. manguro@yahoo.com
Ugi
Ivar
I
Hermann
Rudolf
R
Lemmen
Peter
P
D005419:Flavonoids / Q000737:chemistry*; D044948:Flavonols; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry* / Q000145:classification; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry / Q000145:classification; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry*
D005419:Flavonoids; D044948:Flavonols; D006027:Glycosides; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C437376:drimane