[Effects of 10-day long exposure to gamma irradiation at low doses on bone marrow cells in mice].
Effects of ten day long exposure to gamma-irradiation at low doses (mean dose rate of 1.5-2.0 m Gy/day, total dose of 15 m Gy) on hemopoietic (CFU-S) and stromal (CFU-F) progenitor cells from murine bone marrow were examined. The CFU-F content measured as in vitro fibroblastic colony number showed 1.5-4.5-fold increase. Additionally, the size of ectopic marrow transplants evaluated by counting myelokariocytes and CFU-S numbers also increased. No significant changes of CFU-S proliferation rate were found.
Domaratskaia
E I
EI
Institute of Developmental Biology, Russian Academy of Sciences, Moscow. edomar@proxima.idb.ac.ru
Starostin
V I
VI
Tsetlin
V V
VV
Bueverova
E I
EI
Khrushchov
N G
NG
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000528:radiation effects*; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D005260:Female; D005347:Fibroblasts / Q000528:radiation effects; D005720:Gamma Rays; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011829:Radiation Dosage; D017154:Stromal Cells / Q000528:radiation effects; D013997:Time Factors