title: [The analgesic and antispasmodic effects of guang tong xiao aerosol of TCM].
abstract: OBJECTIVE
  To observe the analgesic and antispasmodic effects of Guang Tong Xiao Aerosol (GTXA).
  
  
  METHODS
  Writhing test and tail-flick of physical stimulation were made to study the analgesic effect on mice and rats.
  
  
  CONCLUSIONS
  GTXA given by gastrogavage in dose of 18.75 g.kg-1 or 12.50 g.kg-1 could markedly raise the pain threshold after chemical stimulation in mice and physical stimulation in rats, and had antispasmodic effects.
authors.affiliation: Department of Immunology, Guang An Men Hospital, China Academy of TCM, Beijing 100053, China.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Wu
authors.forename: G J
authors.initials: GJ
authors.lastname: Wu
authors.forename: B M
authors.initials: BM
authors.lastname: Zhao
authors.forename: J X
authors.initials: JX
authors.lastname: Li
mesh_terms: D000336:Aerosols; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D017288:Pain Threshold / Q000187:drug effects; D010276:Parasympatholytics / Q000494:pharmacology*; D011897:Random Allocation; D051381:Rats; D012007:Rectum / Q000187:drug effects
chemical_list: D000336:Aerosols; D018712:Analgesics, Non-Narcotic; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010276:Parasympatholytics