title: Hypereosinophilia-induced digital necrosis in a smoking patient.
abstract: Raynaud's phenomenon and digital necrosis of the fingers are rare complications of hypereosinophilia. We report a case of a smoking male who developed Raynaud's phenomenon and digital necrosis of the fingers associated with idiopathic hypereosinophilia with angiographically documented occlusion of small and medium arteries of the extremities. The eosinophils may play a thrombotic role in vascular pathology and eosinophil blood count should be checked when investigating patients with digital gangrene.
authors.affiliation: Vascular Diseases and Hypertension, University Hospital of Strasbourg, Strasbourg, France. Dominique.Stephan@chru-strasbourg.fr
authors.forename: D
authors.initials: D
authors.lastname: Stephan
authors.forename: D
authors.initials: D
authors.lastname: Lipsker
authors.forename: P
authors.initials: P
authors.lastname: Sens
authors.forename: S
authors.initials: S
authors.lastname: Hassani
authors.forename: M
authors.initials: M
authors.lastname: Welsch
mesh_terms: D000328:Adult; D005385:Fingers / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D008297:Male; D009336:Necrosis; D011859:Radiography; D011928:Raynaud Disease / Q000209:etiology*; D012907:Smoking / Q000009:adverse effects*