title: [Effect of dan-shen, san-qi of different proportion on platelet aggregation and adhesion in normal rabbits].
abstract: OBJECTIVE
  To observe the effect of the crude extracts of Dan-shen root and San-qi of different proportion on platelet aggregation and adhesion in normal rabbits.
  
  
  METHODS
  With rabbits, ig. (4d, exsanguinated via carotid artery, percentage of platelet aggregation and adhesion was measured.
  
  
  CONCLUSIONS
  Aspirin (4.4 mg/Kg) could markedly inhibit platelet aggregation and adhesion in normal rabbit. The proportions of Dan-shen root/San-qi (10:0, 10:1, 10:3, 10:6, 1:10) could markedly inhibit platelet aggregation, among which 10:3 was the best. San-qi alone had little effect on aggregation. The proportions of Dan-shen root/San-qi (10:3, 10:6, 0:10) could markedly inhibit platelet adhesion, among which 0:10 was the best, and the proportions(10:0, 10:1, 1:10) had little effect.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of TCM, Beijing 100700, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.forename: Cai-ling
authors.initials: CL
authors.lastname: Qin
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Li-yuan
authors.initials: LY
authors.lastname: Kang
authors.forename: You-fu
authors.initials: YF
authors.lastname: Sun
authors.forename: Bo-li
authors.initials: BL
authors.lastname: Zhang
mesh_terms: D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D008297:Male; D005894:Panax / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D011817:Rabbits; D027561:Salvia miltiorrhiza / Q000737:chemistry
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010975:Platelet Aggregation Inhibitors