title: Does preejaculatory penile secretion originating from Cowper's gland contain sperm?
abstract: OBJECTIVE
  To determine if spermatozoa are present in the preejaculatory penile secretion, originating from Cowper's gland.
  
  
  METHODS
  
  
  
  METHODS
  Prospective clinical and laboratory study.
  
  
  METHODS
  Andrology and Sex Counseling Unit, Department of Obstetrics and Gynecology, Academic Teaching Hospital.
  
  
  METHODS
  Five patients referred for premature ejaculation, three for excessive fluid secreted during foreplay and four normal healthy volunteers.
  
  
  METHODS
  Glass slide smears of preejaculatory Cowper's gland secretion obtained during foreplay from at least two different occasions, and semen samples after masturbation.
  
  
  METHODS
  Microscopic examination of air-dried smears, and routine semen analyses.
  
  
  RESULTS
  None of the preejaculatory samples contained sperm. All the patients had sperm in routine sperm analyses.
  
  
  CONCLUSIONS
  Preejaculatory fluid secreted at the tip of the urethra from Cowper's gland during sexual stimulation did not contain sperm and therefore cannot be responsible for pregnancies during coitus interruptus.
authors.affiliation: Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tikva, Israel.
authors.forename: Zvi
authors.initials: Z
authors.lastname: Zukerman
authors.forename: David B
authors.initials: DB
authors.lastname: Weiss
authors.forename: Raoul
authors.initials: R
authors.lastname: Orvieto
mesh_terms: D000328:Adult; D012634:Bodily Secretions / Q000166:cytology*; D002030:Bulbourethral Glands; D006801:Humans; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000378:metabolism*; D013094:Spermatozoa