D-alanine piperazine-amides: novel non-imidazole antagonists of the histamine H3 receptor.
Faghih
R
R
Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, AP-9A, R4MN, Abbott Park, IL 60064-6123, USA. ramin.faghih@abbott.com
Phelan
K
K
Esbenshade
T A
TA
Miller
T R
TR
Kang
C H
CH
Krueger
K M
KM
Yao
B B
BB
Fox
G B
GB
Bennani
Y L
YL
Hancock
A A
AA
D000409:Alanine / Q000737:chemistry; D000577:Amides / Q000737:chemistry; D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D006633:Histamine Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology*; D006801:Humans; D007202:Indicators and Reagents; D007700:Kinetics; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology*; D051381:Rats; D018100:Receptors, Histamine H3 / Q000187:drug effects*; D011994:Recombinant Proteins / Q000378:metabolism
C475225:4-((3-(4-(2-aminopropanoyl)-1-piperazinyl)propoxy)phenyl)cyclopropylmethanone; D000577:Amides; D006633:Histamine Antagonists; D007202:Indicators and Reagents; D010879:Piperazines; D018100:Receptors, Histamine H3; D011994:Recombinant Proteins; D000409:Alanine