title: Optically active polyelectrolyte multilayers as membranes for chiral separations.
abstract: Ultrathin films of chiral polyelectrolyte complex, prepared by the multilayering process, exhibit selectivity in the membrane separations of optically active compounds, such as l- and d-ascorbic acid. The flux through these polyelectrolyte multilayers, PEMUs, is exceptionally high and may be controlled by the concentration of salt present in the permeating solutions. Both in-situ ATR-FTIR and chiral capillary electrochromatography indicate that flux selectivity is mainly kinetically controlled, stemming from a difference in diffusion rates of various enantiomers through PEMUs, rather than a difference in partitioning.
authors.affiliation: Department of Chemistry and Biochemistry, Center for Materials Research and Technology (MARTECH), The Florida State University, Tallahassee, FL 32306, USA.
authors.forename: Hassan H
authors.initials: HH
authors.lastname: Rmaile
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Schlenoff
mesh_terms: D001205:Ascorbic Acid / Q000302:isolation & purification; D004295:Dihydroxyphenylalanine / Q000302:isolation & purification; D004573:Electrolytes / Q000737:chemistry*; D008567:Membranes, Artificial; D010455:Peptides / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism; D014755:Viologens / Q000302:isolation & purification
chemical_list: D004573:Electrolytes; D008567:Membranes, Artificial; D010455:Peptides; D011108:Polymers; D014755:Viologens; D004295:Dihydroxyphenylalanine; D001205:Ascorbic Acid