title: [Clinical observation on treatment of Russula subnigricans poisoning patients by Ganoderma lucidum decoction].
abstract: OBJECTIVE
  To observe the effect of Ganoderma lucidum decoction in treating Russula subnigricans poisoning (RSP) patients.
  
  
  METHODS
  The 14 patients of RSP in the treated group were treated with GLD (GLD, one dose was prepared by 100 g of Ganoderma lucidum decocted with water to 600 ml), on the base of conventional treatment, and 11 patients received conventional therapy in the previous year were taken as control. The clinical efficacy and parameters in them were compared, including the urine N-acetyl-D-glucosaminidase (NAG, which reflects the injury of kidney), the red blood cell and protein in urine, the alanine transaminase (ALT, which reflects the injury of liver), and the aspartate aminotransferase (AST, which reflects the injury of heart).
  
  
  RESULTS
  A better clinical cure-markedly improving rate was showed in the treated group as compared with the control group, P < 0.01. In the treated group, red blood cell in urine disappeared after 24 hrs treatment in the majority of patients, urinary protein reduced obviously and the other three parameters reached the peak at the 3rd day then lowered gradually. In the control group, all the parameters increased continuously. Comparison between the parameters at corresponding time in the two groups showed significant difference (P < 0.01), those in the treated group were markedly lower than those in the control group respectively.
  
  
  CONCLUSIONS
  GLD has good effect in treating RSP, could obviously lower the fatat rate of RSP.
authors.affiliation: Xiangya Hospital, Central South University, Changsha 410008.
authors.forename: Gui-lin
authors.initials: GL
authors.lastname: Xiao
authors.forename: Fa-yi
authors.initials: FY
authors.lastname: Liu
authors.forename: Zuo-hong
authors.initials: ZH
authors.lastname: Chen
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000188:drug therapy*; D008517:Phytotherapy; D020940:Reishi / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000118:Acetylglucosaminidase