title: The European Schizophrenia Outpatient Health Outcomes Study: baseline findings across country and treatment.
abstract: OBJECTIVE
  To describe the baseline findings and study population of the Schizophrenia Outpatient Health Outcomes (SOHO) Study.
  
  
  METHODS
  The SOHO study is an ongoing, large, prospective, long-term observational study of schizophrenia treatment in 10 European countries. The study population consists of out-patients who initiate therapy or change to a new antipsychotic.
  
  
  RESULTS
  A total of 1096 investigators enrolled 10 972 patients. Approximately 60% of patients were men and the mean age was 40 years. Patients treated with clozapine and more than one antipsychotic are more severely ill, patients receiving depot medications have a history of non-compliance, and patients receiving their first antipsychotic for schizophrenia are most likely to receive an atypical agent.
  
  
  CONCLUSIONS
  The SOHO study population appears to represent European out-patients with schizophrenia in whom a treatment decision is required. Baseline findings reflect European clinical practice with respect to patients treated with individual antipsychotics.
authors.affiliation: Research and Development Unit, Sant Joan de Déu-SSM, Sant Boi, Barcelona, Spain. 27652jha@comb.es
authors.forename: J M
authors.initials: JM
authors.lastname: Haro
authors.forename: E T
authors.initials: ET
authors.lastname: Edgell
authors.forename: P
authors.initials: P
authors.lastname: Frewer
authors.forename: J
authors.initials: J
authors.lastname: Alonso
authors.forename: P B
authors.initials: PB
authors.lastname: Jones
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000191:economics; D014150:Antipsychotic Agents / Q000191:economics / Q000627:therapeutic use*; D001569:Benzodiazepines; D005060:Europe; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D010890:Pirenzepine / Q000031:analogs & derivatives* / Q000191:economics / Q000627:therapeutic use*; D011446:Prospective Studies; D012559:Schizophrenia / Q000188:drug therapy* / Q000191:economics*; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine