Concise total synthesis of (+/-)-maritidine.
[reaction: see text] Maritidine can be readily obtained from the corresponding protected beta,gamma-unsaturated ketone. The quaternary carbon of maritidine was created for the first time via an intramolecular Heck reaction.
Bru
Claire
C
Institut de Chimie des Substances Naturelles, CNRS Avenue de la Terrasse 91198 Gif-sur-Yvette, France.
Thal
Claude
C
Guillou
Catherine
C
D000586:Amination; D002384:Catalysis; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D007659:Ketones / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D006576:Heterocyclic Compounds, 4 or More Rings; D007202:Indicators and Reagents; D007659:Ketones; C476903:maritidine