Unilateral subthalamic deep brain stimulation in advanced Parkinson's disease.
Eight patients with advanced PD received a unilateral STN DBS. The UPDRS III off drug-on DBS was improved by a mean 44%. Dyskinesias were ameliorated. Levodopa daily dose was reduced. Three patients required the implantation of the second electrode. Unilateral DBS may be efficacious in some patients with advanced PD.
Linazasoro
Gurutz
G
Centro de Neurología y Neurocirugía funcional, Clínica Quirón, San Sebastián, Guipúzcoa, Spain. glinazasora@terra.es
Van Blercom
Nadège
N
Lasa
Asier
A
D000368:Aged; D000978:Antiparkinson Agents / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004599:Electric Stimulation Therapy / Q000379:methods*; D004567:Electrodes, Implanted; D005260:Female; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000601:surgery*
D000978:Antiparkinson Agents; D007980:Levodopa