title: Symbolic dynamics of jejunal motility in the irritable bowel.
abstract: Different studies of the irritable bowel syndrome (IBS) by conventional analysis of jejunal motility report conflicting results. Therefore, our aim is to quantify the jejunal contraction activity by symbolic dynamics in order to discriminate between IBS and control subjects. Contraction amplitudes during fasting motility (phase II) are analyzed for 30 IBS and 30 healthy subjects. On the basis of a particular scale-independent discretization of the contraction amplitudes with respect to the median, IBS patients are characterized by increased block entropy as well as increased mean contraction amplitude. In a further more elementary level of analysis these differences can be reduced to specific contraction patterns within the time series, namely the fact that successive large contraction amplitudes are less ordered in IBS than in controls. These significant differences in jejunal motility may point to an altered control of the gut in IBS, although further studies on a representative number of patients have to be done for a validation of these findings. (c) 1999 American Institute of Physics.
authors.affiliation: Max-Planck-Institute for Physics of Complex Systems, 01187-Dresden, Germany.
authors.forename: Renate
authors.initials: R
authors.lastname: Wackerbauer
authors.forename: Thomas
authors.initials: T
authors.lastname: Schmidt