Tumor suppression through angiogenesis inhibition.
Arsham
Andrew M
AM
Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, USA.
Simon
M Celeste
MC
D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D030801:Animals, Genetically Modified; D002461:Cell Line, Transformed; D016207:Cytokines / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D004622:Embryo, Mammalian / Q000166:cytology; D016147:Genes, Tumor Suppressor; D006801:Humans; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D016023:Integrins / Q000378:metabolism; D020782:Matrix Metalloproteinases / Q000378:metabolism; D009154:Mutation; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000098:blood supply; D009389:Neovascularization, Pathologic; D009687:Nuclear Proteins / Q000378:metabolism; D040262:Receptors, Vascular Endothelial Growth Factor / Q000378:metabolism; D019699:Thrombospondins / Q000378:metabolism; D014157:Transcription Factors; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
D020533:Angiogenesis Inhibitors; D016207:Cytokines; D004268:DNA-Binding Proteins; C497442:HIF1A protein, human; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D016023:Integrins; D009687:Nuclear Proteins; D019699:Thrombospondins; D014157:Transcription Factors; D042461:Vascular Endothelial Growth Factor A; D040262:Receptors, Vascular Endothelial Growth Factor; D020782:Matrix Metalloproteinases