title: Complex spiral wave dynamics in a spatially distributed ionic model of cardiac electrical activity.
abstract: This study presents computations and analysis of the dynamics of reentrant spiral waves in a realistic model of cardiac electrical activity, incorporating the Beeler-Reuter equations into a two-dimensional cable model. In this medium, spiral waves spontaneously break up, but may be stabilized by shortening the excitation pulse duration through an acceleration of the dynamics of the calcium current. We describe the breakup of reentrant waves based on the presence of slow recovery fronts within the medium. This concept is introduced using examples from pulse circulation around a ring and extended to two-dimensional propagation. We define properties of the restitution and dispersion relations that are associated with slow recovery fronts and promote spiral breakup. The role of slow recovery fronts is illustrated with concrete examples from numerical simulations. (c) 1996 American Institute of Physics.
authors.affiliation: Program in Applied Mathematics, University of Arizona, Tucson, ArizonaCenter for Nonlinear Dynamics in Physiology and Medicine, McGill University, Montreal, Quebec, Canada.
authors.forename: Marc
authors.initials: M
authors.lastname: Courtemanche