Multiple squamous cell carcinomas complicating linear porokeratosis.
Linear porokeratosis is a distinctive variant of porokeratosis with malignant transformation, a known but infrequently reported complication. We report a case of linear porokeratosis on the right leg of a 57-year-old man present since infancy that, over a 2-year period, developed two squamous cell carcinomas within the lesion. Concurrent right inguinal lymphadenopathy was demonstrated on biopsy to be reactive in nature.
Curnow
Paul
P
Department of Dermatology, St Vincent's Hospital Melbourne, Victoria, Australia.
Foley
Peter
P
Baker
Christopher
C
D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D017499:Porokeratosis / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016038:Skin Transplantation; D013997:Time Factors; D016896:Treatment Outcome