Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a therapy approaching evidence-based standards.
DBS of the STN is one of the most promising new therapies for the treatment of PD. However - like many other therapies for PD - the present stage of the scientific assessment does not yet suffice the rigid criteria of evidence-based medicine. Further studies should specifically address the questions of efficacy and side effects as well as the impact on quality of life.
Deuschl
G
G
Department of Neurology, Christian-Albrechts-Universität Kiel, Niemannsweg 147, 24105 Kiel, Germany. g.deuschl@neurologie.uni-kiel.de
Wenzelburger
R
R
Kopper
F
F
Volkmann
J
J
D020820:Dyskinesias / Q000628:therapy; D004558:Electric Stimulation; D004599:Electric Stimulation Therapy / Q000379:methods*; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D010300:Parkinson Disease / Q000628:therapy*; D018579:Patient Selection; D020531:Subthalamic Nucleus / Q000601:surgery*