title: FEARless in meiosis.
abstract: Degradation of mitotic cyclins is critical for exit from mitosis. Recent studies in budding yeast address the role of cyclin degradation in meiosis. Cyclin stabilization in meiosis I interferes with anaphase I spindle disassembly but, surprisingly, does not halt progression into meiosis II.
authors.affiliation: Cell Press, 1100 Massachusetts Avenue, Cambridge, MA 02138, USA.
authors.forename: Bodo M
authors.initials: BM
authors.lastname: Stern
mesh_terms: D000705:Anaphase / Q000235:genetics; D018797:Cell Cycle Proteins / Q000235:genetics*; D016213:Cyclins / Q000235:genetics / Q000378:metabolism*; D010450:Endopeptidases; D005656:Fungal Proteins / Q000235:genetics; D008540:Meiosis / Q000235:genetics*; D008869:Microtubule-Associated Proteins / Q000235:genetics; D009687:Nuclear Proteins; D017027:Protein Tyrosine Phosphatases / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*; D064247:Separase; D008941:Spindle Apparatus / Q000235:genetics
chemical_list: C074860:CDC14 protein, S cerevisiae; D018797:Cell Cycle Proteins; D016213:Cyclins; D005656:Fungal Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; C416648:SPO12 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; C437104:Slk19 protein, S cerevisiae; D017027:Protein Tyrosine Phosphatases; D010450:Endopeptidases; D064247:Separase