title: Carotenoid-radical interactions.
abstract: Carotenoids have been reported to react with virtually any radical species likely to be encountered in a biological system. The products of such reactions are frequently short-lived radical species that can decay to more stable products. In some cases, stable adducts can be observed, but in the majority of interactions with radicals, carotenoids break down to degradation products very similar to what is seen with oxidative degradation. It is only recently that the biological activity of these breakdown products has begun to be investigated.
authors.affiliation: Department of Biochemistry, School of Medicine, Tufts University, Boston, MA 02111, USA. noman.krinsky@tufts.edu
authors.forename: Norman I
authors.initials: NI
authors.lastname: Krinsky
authors.forename: Kyung-Jin
authors.initials: KJ
authors.lastname: Yeum
mesh_terms: D001205:Ascorbic Acid / Q000378:metabolism; D002338:Carotenoids / Q000737:chemistry* / Q000378:metabolism*; D005609:Free Radicals / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008956:Models, Chemical; D024502:alpha-Tocopherol / Q000378:metabolism
chemical_list: D005609:Free Radicals; D002338:Carotenoids; D024502:alpha-Tocopherol; D001205:Ascorbic Acid