Cortical ependymoma. A case report and review.
The authors report a rare case of a cortical ependymoma in a 10-year-old boy. The patient presented with complex partial seizures and a well-circumscribed, right frontal cortical mass. Routine microscopy showed a glial tumor with diverse histologic features. Immunohistochemistry and electron microscopy were required to establish the definitive diagnosis of cortical ependymoma. Cortical-based pediatric brain tumors range from World Health Organization grade I to III lesions and require significantly different treatment and follow-up. This case illustrates the importance of establishing an accurate neuropathologic tissue diagnosis of all pediatric cortical tumors.
Lehman
Norman L
NL
Department of Pathology, Stanford University Medical Center, Calif 94305, USA. nlehman@stanford.edu
Jorden
Michelle A
MA
Huhn
Stephen L
SL
Barnes
Patrick D
PD
Nelson
Gregg B
GB
Fisher
Paul G
PG
Horoupian
Dikran S
DS
D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D002540:Cerebral Cortex / Q000473:pathology* / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male