Granulomatous slack skin: treatment with extensive surgery and review of the literature.
We report an 11-year follow-up of a case of granulomatous slack skin. The patient was first treated surgically followed by a rapid relapse. Then he was treated by alpha-interferon during 15 months. When this treatment was stopped, the disease relapsed again. Extensive surgery was undertaken. Recently, a new relapse has occurred which was again treated by extensive surgery. No other manifestation of a lymphoproliferative disorder appeared. The clinical, histological, immunohistochemical, ultrastructural, molecular biological and genetic studies with a review of 39 other cases described in the literature are presented.
Clarijs
Magali
M
Department of Dermatology, Clinique Notre-Dame-de-Grâce, Charleroi, Belgium.
Poot
Françoise
F
Laka
Andoni
A
Pirard
Christian
C
Bourlond
André
A
D000328:Adult; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000601:surgery*; D008297:Male; D012008:Recurrence; D012878:Skin Neoplasms / Q000601:surgery*; D016896:Treatment Outcome