The paradoxical relationship between NHEJ and telomeric fusion.
Recent results shed new light on the origin of fusion products observed in the destabilized chromosomes of cancer and related diseases. These findings define an unusual relationship between nonhomologous end joining (NHEJ) and telomere "capping," with identical proteins playing opposing roles.
Williams
Bridget
B
Department of Biochemistry, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.
Lustig
Arthur J
AJ
D002455:Cell Division / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D019457:Chromosome Breakage / Q000235:genetics; D005057:Eukaryotic Cells / Q000378:metabolism*; D019098:Telomerase / Q000235:genetics*; D016615:Telomere / Q000235:genetics*; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism
D019098:Telomerase