title: The analysis of an intracerebral hematoma for drugs of abuse.
abstract: Toxicological investigations were performed on an intracerebral hematoma, antemortem blood, and postmortem blood of an individual who was found unresponsive in his home. The hematoma was found to have ethanol at a concentration of 0.05% (w/v), and benzoylecgonine (a cocaine metabolite) was also confirmed at a concentration of 0.43 mg/L by specific analysis using gas chromatography/mass spectrometry (GC/MS). These results enabled the pathologist to record the cause of death as intracerebral hemorrhage due to acute cocaine intoxication.
authors.affiliation: County of San Diego Medical Examiner's Office, 5555 Overland Ave., Bldg. 14, San Diego, CA 92123-12701, USA.
authors.forename: Iain M
authors.initials: IM
authors.lastname: McIntyre
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Hamm
authors.forename: James L
authors.initials: JL
authors.lastname: Sherrard
authors.forename: Ray D
authors.initials: RD
authors.lastname: Gary
authors.forename: Angela C
authors.initials: AC
authors.lastname: Riley
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Lucas
mesh_terms: D002492:Central Nervous System Depressants / Q000009:adverse effects / Q000032:analysis; D002543:Cerebral Hemorrhage / Q000139:chemically induced*; D003042:Cocaine / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000032:analysis; D018765:Dopamine Uptake Inhibitors / Q000009:adverse effects* / Q000032:analysis; D000431:Ethanol / Q000009:adverse effects / Q000032:analysis; D005554:Forensic Medicine / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry; D006406:Hematoma / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D015813:Substance Abuse Detection / Q000379:methods*
chemical_list: D002492:Central Nervous System Depressants; D018765:Dopamine Uptake Inhibitors; D000431:Ethanol; C005618:benzoylecgonine; D003042:Cocaine