title: Obsessive-compulsive disorder in childhood and adolescence.
abstract: Obsessive-compulsive disorder (OCD) is a common psychiatric condition during childhood and adolescence, which continues to be underestimated and undertreated. For these reasons, it constitutes a primary cause of major disabilities in those ages and, sometimes, of permanent impairments later on. In these last few years, childhood and adolescence OCD has attracted an increasing focus which has promoted a deeper awareness of this illness, a better recognition with earlier interventions, as well as the set-up of more tailored and specific strategies, including psychotropic drugs. The aim of this paper is to present a critical review of paediatric OCD, with a special attention towards the most compelling reports available up to now and towards the most interesting areas for future research.
authors.affiliation: Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, via Roma 67, I-56100 Pisa, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Presta
authors.forename: D
authors.initials: D
authors.lastname: Marazziti
authors.forename: L
authors.initials: L
authors.lastname: Dell'Osso
authors.forename: C
authors.initials: C
authors.lastname: Pfanner
authors.forename: P
authors.initials: P
authors.lastname: Pfanner
authors.forename: M
authors.initials: M
authors.lastname: Marcheschi
authors.forename: G
authors.initials: G
authors.lastname: Masi
authors.forename: F
authors.initials: F
authors.lastname: Muratori
authors.forename: M
authors.initials: M
authors.lastname: Mucci
authors.forename: S
authors.initials: S
authors.lastname: Millepiedi
authors.forename: G B
authors.initials: GB
authors.lastname: Cassano
mesh_terms: D002997:Clomipramine / Q000627:therapeutic use; D015928:Cognitive Behavioral Therapy / Q000379:methods; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D017397:Prefrontal Cortex / Q000378:metabolism / Q000503:physiopathology*; D012701:Serotonin / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D002997:Clomipramine; D012701:Serotonin; D017367:Selective Serotonin Reuptake Inhibitors