title: [Late onset diffuse lamellar keratitis].
abstract: BACKGROUND
  Diffuse lamellar keratitis (DLK) is marked by the presence of diffuse or multifocal infiltrates confined to the laser in situ keratomileusis(LASIK) interface. These infiltrates are culture-negative, and the etiology is thought to be noninfectious. Most cases of DLK occur within the first week or two following surgery.
  
  
  METHODS
  We describe two cases of diffuse lamellar keratitis that occurred 3 months after LASIK. These patients were treated with intensive topical corticosteroids.
  
  
  RESULTS
  We treated the patients with topical corticosteroids, with rapid improvement in patient symptoms, visual acuity, and slit-lamp biomicroscopy.
  
  
  CONCLUSIONS
  DLK may occur three months after LASIK.
authors.affiliation: Department of Ophthalmology, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara 228-8555, Japan.
authors.forename: Rie
authors.initials: R
authors.lastname: Amano
authors.forename: Koji
authors.initials: K
authors.lastname: Ohno
authors.forename: Kimiya
authors.initials: K
authors.lastname: Shimizu
authors.forename: Masanobu
authors.initials: M
authors.lastname: Suzuki
authors.forename: Daisuke
authors.initials: D
authors.lastname: Aizawa
authors.forename: Mari
authors.initials: M
authors.lastname: Komatsu
mesh_terms: D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000209:etiology; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects; D008297:Male; D008875:Middle Aged
chemical_list: D005938:Glucocorticoids