title: Percutaneous chemical ablation of desmoid tumors.
abstract: Desmoid tumors are rare fibroblastic neoplasms characterized by highly aggressive local invasion and high recurrence rates after surgical excision. Responses to chemotherapy and radiation therapy are uncommon. The use of percutaneous chemical ablation performed under imaging guidance is described in two patients with recurrent and/or unresectable disease. A complete response was achieved in one patient and a partial response was achieved in the other patient; these responses were sustained during 2 years of follow-up. This technique may hold promise in the treatment of these challenging lesions.
authors.affiliation: Section of Vascular and Interventional Radiology, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA. clark@rad.upenn.edu
authors.forename: Timothy W I
authors.initials: TW
authors.lastname: Clark
mesh_terms: D019342:Acetic Acid / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D005260:Female; D018222:Desmoid Tumors / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008643:Mesentery; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed
chemical_list: D019342:Acetic Acid