title: Cell brain: a new focus in the postgenomic era.
abstract: The centrosome, together with the embedded centrioles and connecting filaments, has come to be regarded as the 'brain' of a cell, analogous to the long known brain of an animal or a human being. It is through the 'brain' that different cellular activities are coordinated as a whole. In this article, comparative studies of the principles of life at varying levels and of the new roles of different cellular organelles in maintaining a healthy life for an organism provide further support to this theory, which is discussed based on the latest findings. Hopefully, this new theory can make a great contribution to break the paradigm of nucleus (or genes) as causes of all problems.
authors.affiliation: Cell Brain Research Center, Shandong University, Jinan, Shandong Province, China. cellbrain2k@yahoo.com
authors.forename: Q
authors.initials: Q
authors.lastname: Kong
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D018385:Centrosome / Q000648:ultrastructure*; D004247:DNA / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D015388:Organelles
chemical_list: D004247:DNA