title: Screening for inhibitors of transcription factors using luciferase reporter gene expression in transfected cells.
authors.affiliation: Roche Pharmaceuticals, Palo Alto, CA, USA.
authors.forename: Deborah
authors.initials: D
authors.lastname: Phippard
authors.forename: Anthony M
authors.initials: AM
authors.lastname: Manning
mesh_terms: D003637:DEAE-Dextran; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D017930:Genes, Reporter; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007202:Indicators and Reagents; D019476:Insect Proteins / Q000032:analysis* / Q000235:genetics; D019169:Jurkat Cells / Q000187:drug effects; D008156:Luciferases / Q000032:analysis* / Q000235:genetics; D009930:Organic Chemicals; D010835:Phytohemagglutinins / Q000494:pharmacology; D011993:Recombinant Fusion Proteins / Q000032:analysis / Q000235:genetics; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014157:Transcription Factors / Q000037:antagonists & inhibitors*; D014162:Transfection; D000813:Anilides; D001549:Benzamides; D011743:Pyrimidines
chemical_list: D003637:DEAE-Dextran; D007166:Immunosuppressive Agents; D007202:Indicators and Reagents; D019476:Insect Proteins; D008156:Luciferases; D009930:Organic Chemicals; D010835:Phytohemagglutinins; D011993:Recombinant Fusion Proteins; D013755:Tetradecanoylphorbol Acetate; D014157:Transcription Factors; C102914:N-(3,5-bis(trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide; D000813:Anilides; D001549:Benzamides; D011743:Pyrimidines