title: A multifactor complex of eIF1, eIF2, eIF3, eIF5, and tRNA(i)Met promotes initiation complex assembly and couples GTP hydrolysis to AUG recognition.
authors.affiliation: Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: K
authors.initials: K
authors.lastname: Asano
authors.forename: L
authors.initials: L
authors.lastname: Phan
authors.forename: L
authors.initials: L
authors.lastname: Valásek
authors.forename: L W
authors.initials: LW
authors.lastname: Schoenfeld
authors.forename: A
authors.initials: A
authors.lastname: Shalev
authors.forename: J
authors.initials: J
authors.lastname: Clayton
authors.forename: K
authors.initials: K
authors.lastname: Nielsen
authors.forename: T F
authors.initials: TF
authors.lastname: Donahue
authors.forename: A G
authors.initials: AG
authors.lastname: Hinnebusch
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D005075:Biological Evolution; D017124:Conserved Sequence; D015977:Eukaryotic Initiation Factor-1 / Q000235:genetics / Q000378:metabolism*; D015852:Eukaryotic Initiation Factor-2 / Q000235:genetics / Q000378:metabolism*; D039621:Eukaryotic Initiation Factor-3 / Q000235:genetics / Q000378:metabolism*; D040061:Eukaryotic Initiation Factor-5 / Q000235:genetics / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000378:metabolism*; D010442:Peptide Chain Initiation, Translational / Q000235:genetics*; D014176:Protein Biosynthesis; D012358:RNA, Transfer, Met / Q000235:genetics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000235:genetics
chemical_list: D015977:Eukaryotic Initiation Factor-1; D015852:Eukaryotic Initiation Factor-2; D039621:Eukaryotic Initiation Factor-3; D040061:Eukaryotic Initiation Factor-5; D012358:RNA, Transfer, Met; D006160:Guanosine Triphosphate