Inflammation and adaptive immune responses to adenoviral vectors injected into the brain: peculiarities, mechanisms, and consequences.
Lowenstein
P R
PR
Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Castro
M G
MG
D000256:Adenoviridae / Q000235:genetics*; D000257:Adenoviridae Infections / Q000276:immunology*; D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D001921:Brain / Q000276:immunology*; D016207:Cytokines / Q000276:immunology; D004660:Encephalitis / Q000276:immunology* / Q000821:virology; D015316:Genetic Therapy / Q000009:adverse effects*; D005822:Genetic Vectors / Q000008:administration & dosage / Q000276:immunology*; D006801:Humans; D007276:Injections, Intraventricular; D013601:T-Lymphocytes / Q000276:immunology; D014759:Viral Envelope Proteins / Q000276:immunology
D000956:Antigens, Viral; D016207:Cytokines; D014759:Viral Envelope Proteins