Angiogenesis in health and disease.
Blood vessels constitute the first organ in the embryo and form the largest network in our body but, sadly, are also often deadly. When dysregulated, the formation of new blood vessels contributes to numerous malignant, ischemic, inflammatory, infectious and immune disorders. Molecular insights into these processes are being generated at a rapidly increasing pace, offering new therapeutic opportunities that are currently being evaluated.
Carmeliet
Peter
P
Center for Transgene Technology and Gene Therapy, Flanders Interuniversitary Institute for Biotechnology, KULeuven, Campus Gasthuisberg, Herestraat 49, B-3000, Leuven, Belgium. peter.carmeliet@med.kuleuven.ac.be
D000818:Animals; D001777:Blood Coagulation; D001808:Blood Vessels / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D009369:Neoplasms / Q000098:blood supply; D009389:Neovascularization, Pathologic; D018919:Neovascularization, Physiologic; D015398:Signal Transduction / Q000502:physiology; D013234:Stem Cells / Q000502:physiology