title: Modeling and simulation of pulsatile blood flow with a physiologic wave pattern.
abstract: This article presents a computational fluid dynamics (CFD) model to analyze pulsatile blood flow in a human artery. The model assumes the vessel as being a straight wall tube, and the blood flow is considered to be incompressible, Newtonian, and axisymmetric. Physiologically realistic resting conditions were adopted for the simulation tests. The main objective was to identify regions where pulsatile effects were significant. Velocity profiles were obtained for both normal and stenosed vessels. The results have shown that, for normal vessels, pulsatile effects prevail close to the vessel wall. The presence of stenosed sections resulted in flow alterations, with flow recirculation areas changing both size and location during the cardiac cycle. These results are especially important in the design of artificial organs. The knowledge of the flow pattern in complex geometries such as artificial hearts, prosthetic valves, and ventricular assist devices can help avoid or minimize thrombogenesis and hemolysis.
authors.affiliation: Departamento de Engenharia Química, UFMG, Belo Horizonte, MG, Brazil.
authors.forename: Paula Freitas
authors.initials: PF
authors.lastname: Marques
authors.forename: Marcos Enê Chaves
authors.initials: ME
authors.lastname: Oliveira
authors.forename: Adriana S
authors.initials: AS
authors.lastname: Franca
authors.forename: Marcos
authors.initials: M
authors.lastname: Pinotti
mesh_terms: D001158:Arteries / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D003198:Computer Simulation; D018056:Hemorheology / Q000379:methods*; D006801:Humans; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology