title: Chlorinated acetylenes from the San Diego sponge Haliclona lunisimilis.
abstract: The sponge Haliclona lunisimilis from Point Loma, California, contained six known chlorinated acetylenes, previously isolated from the dorid nudibranch Diaulula sandiegensis, and three new metabolites, (1Z,3Z)-1-chlorohexadeca-1,3-diene-5,7-diyne-14-ol, (1Z,3E,9Z)-15-acetoxy-1-chlorohexadeca-5,7-diyne-1,3,9-triene, and (1Z,3E)-14-acetoxy-1-chlorohexadeca-1,3-diene-5,7-diyne. The structures of the new compounds were elucidated by interpretation of spectroscopic data. The relationship between the sponge metabolites and the nudibranch metabolites is discussed.
authors.affiliation: Scripps Institution of Oceanography, University of California at San Diego, La Jolla 92093-0212, USA. rdejesus@ucsd.edu
authors.forename: Roman P
authors.initials: RP
authors.lastname: De Jesus
authors.forename: D John
authors.initials: DJ
authors.lastname: Faulkner
mesh_terms: D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D000818:Animals; D002140:California; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006843:Hydrocarbons, Chlorinated; D000114:Acetylene