Type 2 diabetes mellitus in adolescence: lipid and cardiovascular risk factors.
This review discusses the important consequences of dyslipidemia and arteriosclerosis in type 2 diabetes as documented in studies in adults. It then examines the relatively recent upsurge in type 2 diabetes in children and adolescents, its characteristics, and its importance in directing our attention to cardiovascular risk factors in this age group. The discussion concludes with an examination of the information available about arteriosclerosis in the young and about the treatment of hypercholesterolemia in children and adolescents.
Jones
Kenneth Lee
KL
Department of Pediatrics, University of California, San Diego, 9500 Gilman Avenue, La Jolla, CA 92093-0831, USA. kljones@ucsd.edu
Dewan
Asheesh Kumar
AK
D000293:Adolescent; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000453:epidemiology*; D004359:Drug Therapy, Combination; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000150:complications; D024821:Metabolic Syndrome / Q000503:physiopathology*; D012307:Risk Factors
D000924:Anticholesteremic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors