title: IkappaB kinase and NF-kappaB signaling in response to pro-inflammatory cytokines.
authors.affiliation: University of California at San Diego, La Jolla, USA.
authors.forename: Mireille
authors.initials: M
authors.lastname: Delhase
mesh_terms: D016475:3T3 Cells / Q000737:chemistry / Q000187:drug effects; D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis; D002478:Cells, Cultured; D016207:Cytokines / Q000096:biosynthesis / Q000235:genetics; D024202:Electrophoretic Mobility Shift Assay / Q000379:methods; D004926:Escherichia coli; D005786:Gene Expression Regulation / Q000187:drug effects* / Q000502:physiology; D006367:HeLa Cells / Q000737:chemistry / Q000187:drug effects; D006801:Humans; D051550:I-kappa B Kinase; D020672:I-kappa B Proteins / Q000235:genetics / Q000378:metabolism*; D007202:Indicators and Reagents; D007375:Interleukin-1 / Q000494:pharmacology*; D007553:Isotope Labeling / Q000379:methods; D008322:Mammals; D051379:Mice; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000032:analysis* / Q000502:physiology; D010761:Phosphorus Radioisotopes; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D017346:Protein Serine-Threonine Kinases / Q000032:analysis* / Q000737:chemistry / Q000502:physiology; D021122:Protein Subunits; D011993:Recombinant Fusion Proteins; D015398:Signal Transduction / Q000187:drug effects*; D014158:Transcription, Genetic; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
chemical_list: D000936:Antigen-Antibody Complex; D016207:Cytokines; D020672:I-kappa B Proteins; D007202:Indicators and Reagents; D007375:Interleukin-1; D016328:NF-kappa B; C000606204:NFKBIA protein, human; C000606205:Nfkbia protein, mouse; D010761:Phosphorus Radioisotopes; D021122:Protein Subunits; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha; D000072000:NF-KappaB Inhibitor alpha; D017346:Protein Serine-Threonine Kinases; C496559:CHUK protein, human; C496564:Chuk protein, mouse; D051550:I-kappa B Kinase; C496560:IKBKB protein, human; C496565:IKBKE protein, human; C496562:Ikbkb protein, mouse; C496566:Ikbke protein, mouse