title: [High radiopathogenic children's loads caused by "low doses" of technogenic chronic radiation].
abstract: To study influence of "low radiodoses" on their early effects, the method to monitor peculiarities for human biochemphysic pathologies caused by technogenic chronic doses divided by natural constant radiation background doses (relative radiation loads as their ratios, RRL) has been developed. High radiolabile coupled system of harmful catabolites of the initiated lipoperoxic cascade with essential radioprotectors (vitamins A and E as natural antioxidants) as pathogenic significant test-objects were monitored. For exposed children low radiation technogenic doses were high enough as RRL to disturb and to dysregulate both systems. For evaluation of individual radiosensitivity significances of age for children especially, as of the biochemical status for both systems are shown. The approach permits to investigate pathologies of studied systems as primary factors for mechanisms of related radiogenic known somatic health secondary consequences and to use it for some important practical applications.
authors.affiliation: Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119991 Russia. neyfakh@fromru.com
authors.forename: E A
authors.initials: EA
authors.lastname: Neĭfakh
mesh_terms: D000367:Age Factors; D000975:Antioxidants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008962:Models, Theoretical; D018384:Oxidative Stress; D011210:Power Plants; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000188:drug therapy / Q000378:metabolism; D011835:Radiation Protection; D011836:Radiation Tolerance; D011837:Radiation-Protective Agents / Q000627:therapeutic use; D018788:Radioactive Hazard Release; D013997:Time Factors; D014455:Ukraine; D014801:Vitamin A / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D011837:Radiation-Protective Agents; D014801:Vitamin A; D014810:Vitamin E