Sesquiterpene lactone glucosides and alkyl glycosides from the fruit of cumin.
From the polar portion of the methanolic extract of cumin (fruit of Cuminum cyminum L.), two sesquiterpenoid glucosides, cuminoside A and B, and two alkyl glycosides were isolated together with five known compounds. Their structures were established as (1S,5S,6S,10S)-10-hydroxyguaia-3,7(11)-dien-12,6-olide beta-D-glucopyranoside, (1R,5R,6S,7S,9S,10R,11R)-1,9-dihydroxyeudesm-3-en-12,6-olide 9-O-beta-D-glucopyranoside, methyl beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside and ethane-1,2-diol 1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside, respectively.
Takayanagi
Tomomi
T
Showa Pharmaceutical University, Higashi-Tamagawagakuen 3, Machida, Tokyo 194-8543, Japan.
Ishikawa
Toru
T
Kitajima
Junichi
J
D028527:Cuminum / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D005959:Glucosidases / Q000378:metabolism; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification
D005960:Glucosides; D007783:Lactones; D012717:Sesquiterpenes; D005959:Glucosidases