title: A case of subacute sclerosing panencephalitis preceded by epileptic seizures: evolutional EEG changes.
abstract: We reported a patient with subacute sclerosing panencephalitis (SSPE) in whom EEG had been serially performed before the onset. She was referred to our hospital due to epileptic seizures at 2 years of age. Focal spikes were seen on EEG at the time of her first seizure (2 years 4 months). At the time of the second unprovoked seizure (9 years 8 months), EEG showed poorly organized background activity associated with focal spikes and a few diffuse spike-and-waves. Then, diffuse paroxysms became predominant, followed by periodic synchronous discharges. In our case, EEG abnormalities were recognized before mental deterioration. Unexpected EEG changes in a patient with epilepsy could be a clue as to the diagnosis of SSPE.
authors.affiliation: Department of Pediatrics, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-Ku, Nagoya, Aichi 466-8550, Japan. t-kubota@med.nagoya-u.ac.jp
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kubota
authors.forename: Akihisa
authors.initials: A
authors.lastname: Okumura
authors.forename: Junko
authors.initials: J
authors.lastname: Takenaka
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Ishiguro
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Norishi
authors.initials: N
authors.lastname: Ueda
authors.forename: Tamiko
authors.initials: T
authors.lastname: Negoro
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D001921:Brain / Q000503:physiopathology*; D002675:Child, Preschool; D018450:Disease Progression; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D012640:Seizures / Q000209:etiology / Q000503:physiopathology*; D013344:Subacute Sclerosing Panencephalitis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*