Impact of five cytochrome p450 enzymes on the metabolism of two heterocyclic aromatic amines, 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC).
Frederiksen
Hanne
H
Institute of Food Safety and Nutrition, Danish Veterinary and Food Administration, Mørkhøj Bygade, Sørborg, Denmark.
Frandsen
Henrik
H
D000818:Animals; D002243:Carbolines / Q000378:metabolism*; D002273:Carcinogens / Q000378:metabolism*; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism; D019388:Cytochrome P-450 CYP1A2 / Q000378:metabolism; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D009153:Mutagens / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D002243:Carbolines; D002273:Carcinogens; D009153:Mutagens; C017821:2-amino-3-methyl-9H-pyrido(2,3-b)indole; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; D019363:Cytochrome P-450 CYP1A1; D019388:Cytochrome P-450 CYP1A2; D051544:Cytochrome P-450 CYP3A; C017822:2-amino-9H-pyrido(2,3-b)indole