Coronary artery surgery for ischaemic heart failure: the surgeon's view.
Recent advances in medical therapy have improved outcomes for patients with severe heart failure. However, overall survival remains poor. Transplantation is an established therapy for these patients but is limited by the large mismatch between demand and donor organ availability. Recently it has been recognised that not all ventricular dysfunction secondary to coronary artery disease is irreversible. Revascularisation in certain patients would appear to improve ventricular function. These patients are said to demonstrate myocardial "hibernation". Revascularisation in these patients may provide a further treatment option in the treatment of heart failure.
Lewis
Michael Edward
ME
Department of Cardiac Surgery, Queen Elizabeth Hospital Medical Centre, Edgbaston, Birmingham, B15 2TH.
Pitt
Michael Paul Ian
MP
Bonser
Robert Stuart
RS
Pagano
Domenico
D
D001026:Coronary Artery Bypass; D003326:Coronary Circulation / Q000502:physiology; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D009200:Myocardial Contraction / Q000502:physiology; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000601:surgery*; D011788:Quality of Life; D013318:Stroke Volume / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology / Q000601:surgery; D016277:Ventricular Function, Left / Q000502:physiology