Influence of suspended solids on acute toxicity of carbofuran to Daphnia magna: I. Interactive effects.
This study explored the effects on Daphnia magna from exposure to the pesticide carbofuran in combination with stress from suspended solids exposure. Our objective was to assess whether suspended solids affects the toxicodynamic response of D. magna to carbofuran. A series of laboratory experiments was performed where animals were exposed to carbofuran concentrations ranging from 0 to 160 microg/l in combination with suspended solids concentrations ranging from 0 to 10000 mg/l. In the absence of suspended solids, effects of carbofuran were dose dependent and resulted in an EC(50) of 92 microg/l. Exposure to suspended solids, up to extreme levels that may be encountered in the environment and in the absence of carbofuran, showed no measurable toxicity. When D. magna were exposed to a constant carbofuran concentration, the numbers of affected organisms increased with increasing suspended solids concentrations. At a suspended solids concentration of 1000 mg/l, the EC(50) for carbofuran was reduced by half to 45 microg/l. The relationship between the toxicity of carbofuran (microg/l) and the concentration of suspended solids (mg/l) can be described with the following equation: carbofuran EC(50)=72 exp(-0.00014 [suspended solids]). An analysis of the data indicates that this relationship is consistent with a potentiated toxicity mechanism rather than an additive model.
Herbrandson
Carl
C
National Biological Service, Minnesota Cooperative Fish and Wildlife Research Unit, University of Minnesota, 200 Hodson Hall, St. Paul, MN 55108, USA.
Bradbury
Steven P
SP
Swackhamer
Deborah L
DL
D000818:Animals; D002235:Carbofuran / Q000737:chemistry* / Q000633:toxicity*; D002800:Cholinesterase Inhibitors / Q000633:toxicity; D003621:Daphnia / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D056890:Eukaryota / Q000737:chemistry; D007306:Insecticides / Q000737:chemistry / Q000633:toxicity; D010574:Pesticide Synergists / Q000737:chemistry / Q000633:toxicity; D013535:Suspensions; D023382:Toxicity Tests, Acute; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D002800:Cholinesterase Inhibitors; D007306:Insecticides; D010574:Pesticide Synergists; D013535:Suspensions; D014874:Water Pollutants, Chemical; D014867:Water; D002235:Carbofuran