On the association between diabetes and mental disorders in a community sample: results from the German National Health Interview and Examination Survey.
OBJECTIVE
To determine the relationship between mental disorders and diabetes in a representative community sample.


METHODS
This was a cross-sectional study. Data on diabetes and HbA(1c) values were obtained by structured questionnaires and by laboratory assessments. Current psychiatric disorders were diagnosed by a modified version of the Composite International Diagnostic Interview (CIDI).


RESULTS
People with diabetes (PWD) were not more likely to meet Diagnostic and Statistical Manual of Psychiatric Disorders, 4th edition (DSM-IV) criteria for at least one mental disorder than were individuals without diabetes. However, a different diagnostic pattern occurred compared with the general population: odds ratios (ORs) for anxiety disorders in PWD were higher (OR 1.93, 95% CI 1.19-3.14). Although PWD had higher prevalence rates of affective disorders, the relationship between diabetes and affective disorders was not statistically significant after controlling for age, sex, marital status, and socioeconomic status. In contrast, the relationship between diabetes and anxiety disorders remained significant after controlling for these variables. In contrast to individuals without mental disorders, PWD with affective or anxiety disorders more frequently had adequate glycemic control.


CONCLUSIONS
Diabetes was associated with an increased likelihood of anxiety disorders. The association between mental disorders, diabetes, and glycemic control should be evaluated carefully in terms of potentially confounding sociodemographic variables, sample characteristics, and definitions of the disorders.
Kruse
Johannes
J
Department of Psychotherapeutic Medicine, Heinrich-Heine University, Duesseldorf, Germany. kruse@uni-duesseldorf.de
Schmitz
Norbert
N
Thefeld
Wolfgang
W
D000328:Adult; D017668:Age of Onset; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D017533:Marital Status; D001523:Mental Disorders / Q000145:classification / Q000150:complications* / Q000453:epidemiology*; D008875:Middle Aged; D012016:Reference Values; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
D006442:Glycated Hemoglobin