title: [Effect of components of dang-gui-bu-xue decoction on hematopenia].
abstract: OBJECTIVE
  To investigate the effects and the related mechanisms of the components of Dang-Gui-Bu-Xue decoction (DGBXD) on improving blood deficiency.
  
  
  METHODS
  The effects of promoting hematopoietic function were observed with the blood difficient model mice, by giving components of DGBXD. RBC, WBC, reticulocytes and bone marrow nucleated cells (BMNC) were determined. The components of DGBXD on proliferation of BMNC and on clony forming unit (CFU) were also determined.
  
  
  RESULTS
  The components of DGBXD remarkably increased the quantity of RBC, WBC, and BMNC. Some of the components promoted the proliferation of BMNC and increased the quantity of CFU-Mix. Among them, polysaccharide of angelica was most potent.
  
  
  CONCLUSIONS
  The studies show that the extracts and some components of DGBXD can promote the hemopoietic function system of the model mice, and they exert the effects in a comprehensive way.
authors.affiliation: Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. lioning@teacher.com
authors.forename: Lian
authors.initials: L
authors.lastname: Ning
authors.forename: Chang-xun
authors.initials: CX
authors.lastname: Chen
authors.forename: Ruo-min
authors.initials: RM
authors.lastname: Jin
authors.forename: Yao-ping
authors.initials: YP
authors.lastname: Wu
authors.forename: Hai-gui
authors.initials: HG
authors.lastname: Zhang
authors.forename: Cheng-li
authors.initials: CL
authors.lastname: Sun
authors.forename: Chun-qing
authors.initials: CQ
authors.lastname: Song
authors.forename: Zhi-bi
authors.initials: ZB
authors.lastname: Hu
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry*; D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry*; D001772:Blood Cell Count; D001854:Bone Marrow Cells / Q000187:drug effects; D003114:Colony-Forming Units Assay; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008813:Mice, Inbred ICR; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D011134:Polysaccharides; C477279:danggui buxue decoction; C044613:angelicae sinensis extract