Transition from diffuse cellular infiltration to extensive nodular granuloma as a manifestation of isolated sarcoidosis in the hand: a case report.
A patient with soft-tissue sarcoidosis of the hand is described. She initially presented with diffuse soft-tissue infiltration in the digits. After a 12-year time period without steroid treatment the patient developed extensive, tumor-like nodular masses involving multiple digits with lesions extending to the fingertips. Variable clinical features of the soft-tissue sarcoidosis of the hand have been reported as distinctive, independent manifestations of the disease. A transition from the diffuse cellular infiltration to the nodular, tumor-like lesions in the present case shows that the isolated soft-tissue sarcoidosis of the hand may exhibit variable clinical features in a single case.
Imai
Shinji
S
Department of Orthopaedic Surgery, Shiga University of Medical Science, Shiga-ken, Japan.
Kubo
Mitsuhiko
M
Andou
Kousei
K
Kikuchi
Katsuhisa
K
Matsusue
Yoshitaka
Y
D005260:Female; D005385:Fingers / Q000473:pathology; D006099:Granuloma / Q000473:pathology*; D006225:Hand; D006801:Humans; D008875:Middle Aged; D012507:Sarcoidosis / Q000473:pathology*; D013583:Synovial Membrane / Q000473:pathology; D013717:Tenosynovitis / Q000473:pathology*