In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene.
Gicquel
Christine
C
Gaston
Véronique
V
Mandelbaum
Jacqueline
J
Siffroi
Jean-Pierre
JP
Flahault
Antoine
A
Le Bouc
Yves
Y
D000818:Animals; D001506:Beckwith-Wiedemann Syndrome / Q000209:etiology*; D019175:DNA Methylation; D016373:DNA, Antisense / Q000235:genetics; D005307:Fertilization in Vitro / Q000009:adverse effects*; D018392:Genomic Imprinting; D006801:Humans; D007438:Introns; D051656:KCNQ Potassium Channels; D051657:KCNQ1 Potassium Channel; D008565:Membrane Proteins; D016017:Odds Ratio; D016012:Poisson Distribution; D015221:Potassium Channels / Q000235:genetics*; D024642:Potassium Channels, Voltage-Gated; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated / Q000235:genetics*; D012306:Risk; D018570:Risk Assessment
D016373:DNA, Antisense; D051656:KCNQ Potassium Channels; D051657:KCNQ1 Potassium Channel; C496909:KCNQ1 protein, human; C449939:KCNQ1OT1 RNA; C485621:KCNQ1OT1 long non-coding RNA, human; D008565:Membrane Proteins; D015221:Potassium Channels; D024642:Potassium Channels, Voltage-Gated; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated