[Expression and distribution of Aquaporin 1 in the nasal polyps].
OBJECTIVE
To confirm the expression and distribution of Aquaporin 1 (AQP1) in the nasal polyps and to investigate the relation between AQP1 and the nasal polyp edema.


METHODS
fourteen cases of normal inferior turbinates and 26 cases of nasal polyps were used. The expression and distribution of AQP1 in nasal polyps were examined by immunohistochemical technique.


RESULTS
The level of AQP1 in the epithelial cells and serous cells from nasal polyps was higher than that in inferior turbinates, and the level of AQP1 in the epithelial cells and cilium cells from inferior turbinate was higher than that in nasal polyps.


CONCLUSIONS
There is close relationship between AQP1 and nasal polyp edema.
Guan
G
G
Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Friendship Hospital, Jilin University, Changchun 130031, China. wangyipe@public.cc.jl.cn
Xu
C
C
Dong
Z
Z
She
C
C
Liu
T
T
Jiang
S
S
D000328:Adult; D000368:Aged; D020346:Aquaporins / Q000096:biosynthesis*; D004487:Edema / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism* / Q000473:pathology
D020346:Aquaporins