title: Candida spp. urinary tract infections in 13 dogs and seven cats: predisposing factors, treatment, and outcome.
abstract: Records from 20 animals (13 dogs, seven cats) with Candida spp. urinary tract infections were reviewed. Six Candida spp. were isolated; Candida albicans was the most common isolate. Concurrent diseases or nonantifungal drugs administered within 1 month of isolation included antibiotics (n=16), corticosteroids (n=6), diabetes mellitus (n=4), nonurogenital neoplasia (n=3), and noncandidal urogenital disease (n=14). All animals had sources of local or systemic immune compromise that likely predisposed to infection. Of five animals with resolution of infection, three did not receive specific antifungal treatment. The authors conclude that correction of predisposing conditions is likely critical for management of Candida spp. urinary tract infection.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA.
authors.forename: Barrak M
authors.initials: BM
authors.lastname: Pressler
authors.forename: Shelly L
authors.initials: SL
authors.lastname: Vaden
authors.forename: India F
authors.initials: IF
authors.lastname: Lane
authors.forename: Larry D
authors.initials: LD
authors.lastname: Cowgill
authors.forename: Janice A
authors.initials: JA
authors.lastname: Dye
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000145:classification / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000453:epidemiology / Q000662:veterinary*; D002371:Cat Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000652:urine; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000652:urine; D004285:Dogs; D005260:Female; D016867:Immunocompromised Host; D008297:Male; D009657:North Carolina / Q000453:epidemiology; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000662:veterinary*
chemical_list: D000935:Antifungal Agents