title: Identification of novel H3 receptor (H3R) antagonists with cognition enhancing properties in rats.
authors.affiliation: Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, AP9A, R4N5, 100 Abbott Park Rd., Abbott Park, Illinois 60064-6115, USA. gerard.b.fox@abbott.com
authors.forename: G B
authors.initials: GB
authors.lastname: Fox
authors.forename: J B
authors.initials: JB
authors.lastname: Pan
authors.forename: R
authors.initials: R
authors.lastname: Faghih
authors.forename: T A
authors.initials: TA
authors.lastname: Esbenshade
authors.forename: A
authors.initials: A
authors.lastname: Lewis
authors.forename: R S
authors.initials: RS
authors.lastname: Bitner
authors.forename: L A
authors.initials: LA
authors.lastname: Black
authors.forename: Y L
authors.initials: YL
authors.lastname: Bennani
authors.forename: M W
authors.initials: MW
authors.lastname: Decker
authors.forename: A A
authors.initials: AA
authors.lastname: Hancock
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003071:Cognition / Q000187:drug effects*; D006633:Histamine Antagonists / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology; D008297:Male; D010879:Piperazines / Q000494:pharmacology; D051381:Rats; D011918:Rats, Inbred SHR; D017207:Rats, Sprague-Dawley; D018100:Receptors, Histamine H3 / Q000187:drug effects*; D012919:Social Behavior
chemical_list: C475225:4-((3-(4-(2-aminopropanoyl)-1-piperazinyl)propoxy)phenyl)cyclopropylmethanone; D006633:Histamine Antagonists; D007093:Imidazoles; C475226:N-(2-(4-(3-(4-(cyclopropylcarbonyl)phenoxy)propyl)-1-piperazinyl)-1-methyl-2-oxoethyl)-2-furamide; D010879:Piperazines; D018100:Receptors, Histamine H3; C115705:ciproxifan