title: Signet-ring cell carcinoma of the ampulla of Vater: report of a case.
abstract: An 83-year-old man was admitted to our hospital complaining of general fatigue, fever, and obstructive jaundice. Percutaneous transhepatic bile duct drainage was performed. Gastroduodenal fiberscopy revealed carcinoma of the ampulla of Vater, and early gastric cancer was suspected. A pancreatoduodenectomy with lymph node dissection was performed. Although a biopsy specimen from the gastric lesion was suspected to be well-differentiated adenocarcinoma, no cancerous lesion was found in a specimen resected from the stomach. The histopathologic findings of the ampullary lesion were compatible with a diagnosis of signet-ring cell carcinoma. This is a rare lesion, and a review of the literature revealed only three previous similar cases.
authors.affiliation: Department of Surgery, Sasebo Kyosai Hospital, 10-17 Shimanji-cho, Sasebo 857-8575, Japan.
authors.forename: Naofumi
authors.initials: N
authors.lastname: Eriguchi
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Aoyagi
authors.forename: Atsuo
authors.initials: A
authors.lastname: Jimi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology* / Q000601:surgery; D003138:Common Bile Duct Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans