title: HLA alleles in isolated populations from North Spain: origin of the Basques and the ancient Iberians.
abstract: HLA-A, -B, -DRB1, -DQA1 and -DQB1 alleles have been studied in three relatively isolated populations of northern Spain from Cantabria ( Pas Valleys inhabitants or Pasiegos and Cabuernigos) and from the Basque Country (Arratia Valley inhabitants). These populations have been compared with neighbouring ones and other Mediterraneans by using neighbour-joining dendrograms and plane genetic distances.
authors.affiliation: Department of Immunology and Molecular Biology, Hosp. 12 de Octubre, Universidad Complutense, Madrid, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Sanchez-Velasco
authors.forename: E
authors.initials: E
authors.lastname: Gomez-Casado
authors.forename: J
authors.initials: J
authors.lastname: Martinez-Laso
authors.forename: J
authors.initials: J
authors.lastname: Moscoso
authors.forename: J
authors.initials: J
authors.lastname: Zamora
authors.forename: E
authors.initials: E
authors.lastname: Lowy
authors.forename: C
authors.initials: C
authors.lastname: Silvera
authors.forename: A
authors.initials: A
authors.lastname: Cemborain
authors.forename: F
authors.initials: F
authors.lastname: Leyva-Cobián
authors.forename: A
authors.initials: A
authors.lastname: Arnaiz-Villena
mesh_terms: D000483:Alleles; D004641:Emigration and Immigration; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D005828:Genetics, Population; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D006683:HLA-DQ Antigens / Q000235:genetics; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; D006684:HLA-DR Antigens / Q000235:genetics; D059811:HLA-DRB1 Chains; D006239:Haplotypes / Q000235:genetics; D049690:History, Ancient; D006801:Humans; D010802:Phylogeny; D011110:Polymorphism, Genetic; D013030:Spain
chemical_list: D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; C069050:HLA-DQA1 antigen; C069051:HLA-DQB1 antigen; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains