title: [Intravascular brachytherapy in the prevention of vascular restenosis].
abstract: Vascular restenoses currently represent a major problem in the treatment of vascular stenoses. One of new approaches in the prevention of restenoses is intravascular brachytherapy. Intravascular brachytherapy uses local irradiation of the stenotic vessel segment by ionizing radiation with the aim of prevention of restenosis. This is a new rapidly developing multidisciplinary approach based on collaboration of specialties of intervention radiology, intervention cardiology, angiology, nephrology and radiation oncology. This review examines current options of intravascular brachytherapy as well as results of clinical trials evaluating the efficacy of intravascular brachytherapy in the different anatomical regions. Intravascular brachytherapy may substantially reduce the rate of restenoses. However, intravascular brachytherapy should be currently used only in the setting of clinical trials. Optimal method of irradiation of the stenotic segment of the vessel is still to be defined.
authors.affiliation: Klinika onkologie a radioterapie FN, Hradec Králové. dvorakj@fnhk.cz
authors.forename: J
authors.initials: J
authors.lastname: Dvorák
authors.forename: J
authors.initials: J
authors.lastname: Petera
authors.forename: J
authors.initials: J
authors.lastname: Fridrich
authors.forename: J
authors.initials: J
authors.lastname: Raupach
authors.forename: A
authors.initials: A
authors.lastname: Krajina
authors.forename: P
authors.initials: P
authors.lastname: Hůlek
authors.forename: B
authors.initials: B
authors.lastname: Melichar
authors.forename: J
authors.initials: J
authors.lastname: Malý
mesh_terms: D000800:Angioplasty, Balloon; D015906:Angioplasty, Balloon, Coronary; D001157:Arterial Occlusive Diseases / Q000517:prevention & control / Q000532:radiotherapy / Q000628:therapy*; D001158:Arteries / Q000528:radiation effects; D001918:Brachytherapy / Q000379:methods; D023903:Coronary Restenosis / Q000517:prevention & control; D006083:Graft Occlusion, Vascular / Q000517:prevention & control; D006801:Humans; D055502:Secondary Prevention