title: [Otorhinolaryngological neurofibromatosis].
abstract: OBJECTIVE
  To investigate the growth characteristic, clinical manifestation, diagnosis and treatment of neurofibromatosis (NF) in otorhinolaryngology.
  
  
  METHODS
  Eleven cases of NF from 1989 to 2000 were analyzed retrospectively, among which, there were 5 and 2 cases occurring in nasal cavity and parapharynx (NF I), respectively, and 4 bilateral acoustic neuromas (NF II).
  
  
  RESULTS
  NF I and NF II had long courses of 2-30 years, with common clinical features and unique characteristics. All patients with NF were operated on under general anesthesia. The NFs in the nasal cavity and sinus were resected through the paranasal approach and parapharyngeal NF through the lateral cervical approach. Unilateral acoustic neuromas were removed via the sigmoid sinus posterior suboccipital approach, one case bilateral acoustic neuromas was operated on in 2 stages. No death happened in this series.
  
  
  CONCLUSIONS
  Surgical treatment is the best way for the treatment of NF. Radiotherapy can be considered in case of NF I with an extensive invasion, obscure border and recurrence.
authors.affiliation: Department of Otorhinolaryngology, The First Affiliated Hospital, Wenzhou Medical College, Wenzhou 325000, China. zyue@mail.wzptt.wzptt.zj.cn
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Zhong
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Li
authors.forename: Jianfu
authors.initials: J
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000601:surgery*; D016518:Neurofibromatosis 2 / Q000601:surgery*; D010039:Otorhinolaryngologic Neoplasms / Q000601:surgery*; D012189:Retrospective Studies