Correlation of biomechanical stiffness with plain radiographic and ultrasound data in an experimental mandibular distraction wound.
The aim of this study was to determine the stiffness of a porcine mandibular distraction wound at the end of neutral fixation.Twenty-four Yucatan minipigs underwent unilateral mandibular distraction: zero-day latency, rates of 1, 2, and 4 mm per day, distraction gap of 12 mm. Radiographic and ultrasound bone fill scores at 0, 8, 16 and 24 days of neutral fixation were used to evaluate interval healing. At sacrifice, biomechanical stiffness was determined using an Instron machine to produce a downward force of 2 mm/min at the premolar occlusal surface. Force (kilo-Newton, kN) and displacement (mm) were recorded at a rate of 10,000 points/second. Stiffness across the distraction wound, plain radiographic and ultrasound bone fill scores all increased with duration of neutral fixation and were highest for the 1 mm per day group at all time points. At the end of fixation, even in the most clinically stable group, stiffness across the distraction wound was only 25.5% of control.Despite clinical stability and high bone fill scores by X-ray and ultrasound, the distraction wound did not achieve normal stiffness at the end of neutral fixation in this model. This may have implications for the management of patients who undergo large movements by distraction.
Kaban
L B
LB
The Department of Oral & Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA, USA. kaban.leonard@mgh.harvard.edu
Thurmüller
P
P
Troulis
M J
MJ
Glowacki
J
J
Wahl
D
D
Linke
B
B
Rahn
B
B
Perrott
D H
DH
D000818:Animals; D015519:Bone Density; D002146:Bony Callus / Q000502:physiology; D003799:Dental Stress Analysis; D005260:Female; D008334:Mandible / Q000000981:diagnostic imaging / Q000502:physiology* / Q000601:surgery*; D019186:Mandibular Advancement / Q000379:methods*; D019857:Osteogenesis, Distraction; D018583:Pliability; D011859:Radiography; D013552:Swine; D013556:Swine, Miniature; D014463:Ultrasonography