title: Brain regions sensitive to the face inversion effect: a functional magnetic resonance imaging study in humans.
abstract: Perception of upright faces relies on configural processing. Therefore recognition of inverted, compared to upright faces is impaired. In a functional magnetic resonance imaging experiment we investigated the neural correlate of a face inversion task. Thirteen healthy subjects were presented with a equal number of upright and inverted faces alternating with a low level baseline with an upright and inverted picture of an abstract symbol. Brain activation was calculated for upright minus inverted faces. For this differential contrast, we found a signal change in the right superior temporal sulcus and right insula. Configural properties are processed in a network comprising right superior temporal and insular cortex.
authors.affiliation: Department of Psychiatry, University of Tuebingen, Osianderstrasse 24, 72076, Tuebingen, Germany. dirk.leube@med.uni-tuebingen.de
authors.forename: Dirk T
authors.initials: DT
authors.lastname: Leube
authors.forename: Hyo Woon
authors.initials: HW
authors.lastname: Yoon
authors.forename: Alexander
authors.initials: A
authors.lastname: Rapp
authors.forename: Michael
authors.initials: M
authors.lastname: Erb
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Grodd
authors.forename: Mathias
authors.initials: M
authors.lastname: Bartels
authors.forename: Tilo T J
authors.initials: TT
authors.lastname: Kircher
mesh_terms: D000328:Adult; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping; D004292:Dominance, Cerebral; D005149:Facial Expression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010364:Pattern Recognition, Visual / Q000502:physiology; D010775:Photic Stimulation; D021641:Recognition, Psychology / Q000502:physiology*