title: In vivo kinetics of bleaching gel with three-percent hydrogen peroxide within the first hour.
abstract: This in vivo study determined the kinetics of 3% hydrogen peroxide in a bleaching gel within the first hour. The material used in this study was 3% hydrogen peroxide gel (Perfecta 3/15, Premier Dental Products Co) and the study involved 10 subjects who met the inclusion and exclusion criteria. Each subject wore the tray with gel six different times on separate days. Evaluation of the remaining amount of hydrogen peroxide was calculated by the method stated in US Pharmacopoeia. The study results indicate that the mean percentage of hydrogen peroxide recovered for 5, 10, 20, 30, 45 and 60 minutes was 61, 56, 49, 44, 38 and 32, respectively. The amount of hydrogen peroxide in the saliva sample after one hour was 0.42 mg. Excluding the first 10 minutes, the kinetics of hydrogen peroxide in the tray and teeth sample was exponential.
authors.affiliation: Department of Restorative Dental Science, King Saud University, College of Dentistry, Saudi Arabia. tqunaian@msn.com
authors.forename: Talal A
authors.initials: TA
authors.lastname: Al-Qunaian
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Matis
authors.forename: Michael A
authors.initials: MA
authors.lastname: Cochran
mesh_terms: D005782:Gels; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D007700:Kinetics; D016877:Oxidants / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D012044:Regression Analysis; D012463:Saliva / Q000737:chemistry; D013997:Time Factors; D014073:Tooth Bleaching / Q000295:instrumentation / Q000379:methods
chemical_list: D005782:Gels; D016877:Oxidants; D006861:Hydrogen Peroxide