Spiral breakup as a model of ventricular fibrillation.
The phenomenon of spiral breakup in a 2D and a 3D excitable medium is described. Differences between breakup in two dimensions and in three dimensions are discussed. Spiral breakup in an anatomical model of the ventricles of the heart is also studied. The patterns of excitation in the heart are presented at different wavelengths together with their electrocardiograms. Finally it is suggested that the phenomenon of spiral breakup is a possible mechanism of the ventricular fibrillation (VF). (c) 1998 American Institute of Physics.
Panfilov
Alexandre V.
AV
Department of Theoretical Biology, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.