[Determination of the immune function of the erythrocyte and leucocyte and the activity of IL-4 and IFN-gamma in patients with allergic rhinitis].
OBJECTIVE
To investigate the immune function of erythrocyte (RBC) and leucocyte (WBC), and variety of the interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) among patients with allergic rhinitis.


METHODS
IL-4 and IFN-gamma secreted by peripheral blood mononuclear cells (PBMC) were measured and compared with immune adhesive and BA-ELISA method.


RESULTS
Results showed the RBC and WBC immune adhesive function and IFN-gamma were significantly decreased than of the control, and IL-4 activity were significantly higher than the controls (P < 0.01) in patients with perennial allergic rhinitis.


CONCLUSIONS
These results suggest that RBC and WBC the immune function and IL-4 and IFN-gamma may play an important role in allergic rhinitis.
Zhou
B
B
Department of Otorhinolaryngology, Affiliated Hospital of Guangdong Medical College, Guangdong, Zhanjang 524001, China. cj3a@163.net
Lü
S
S
Chen
X
X
D000293:Adolescent; D000328:Adult; D002448:Cell Adhesion; D004797:Enzyme-Linked Immunosorbent Assay; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood*; D015847:Interleukin-4 / Q000097:blood*; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology*
D015847:Interleukin-4; D007371:Interferon-gamma