title: The diagnostic dilemma of intraoperative hyperpyrexia in a malaria endemic area.
abstract: Malignant hyperthermia (MH) is a serious and feared complication of general anaesthesia. The diagnosis of MH may pose a diagnostic dilemma, as its two most common signs tachycardia and hyperthermia are also common features of infections, transfusion and drug reactions. We report three cases of hyperthermia occurring during anaesthesia posing diagnostic dilemma in which two of the cases appear to be due to malaria. It is therefore suggested that all patients undergoing anaesthesia in a malaria endemic area should be investigated and treated for malaria if indicated preoperatively even when asymptomatic to prevent such diagnostic confusion.
authors.affiliation: Department of Anaesthesia, College of Medicine University Teaching Hospital, Ibadan, Nigeria.
authors.forename: S D
authors.initials: SD
authors.lastname: Amanor-Boadu
authors.forename: A
authors.initials: A
authors.lastname: Mohammed
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D019353:Endemic Diseases; D005260:Female; D005334:Fever / Q000209:etiology*; D006801:Humans; D007223:Infant; D007431:Intraoperative Complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D008288:Malaria / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008305:Malignant Hyperthermia / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D013514:Surgical Procedures, Operative / Q000009:adverse effects