Multivalent neoglycoconjugates by regiospecific cycloaddition of alkynes and azides using organic-soluble copper catalysts.
[reaction: see text] The construction of multivalent neoglycoconjugates is efficiently achieved by the regiospecific catalytic cycloaddition of alkynes and azides using the organic-soluble copper complexes (Ph(3)P)(3).CuBr and (EtO)(3)P.CuI. The simultaneous use of microwave irradiation shortened notably the reaction times.
Pérez-Balderas
Francisco
F
Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain.
Ortega-Muñoz
Mariano
M
Morales-Sanfrutos
Julia
J
Hernández-Mateo
Fernando
F
Calvo-Flores
Francisco G
FG
Calvo-Asín
Jose A
JA
Isac-García
Joaquín
J
Santoyo-González
Francisco
F