title: Left ventricular filling patterns and pulmonary artery pressures in patients aged 90 to 100 years with normal echocardiography results.
abstract: Left ventricular filling and pulmonary artery pressure (PAP) have not been well described in patients > or = 90 years old. We reviewed our database to obtain echocardiograms with normal findings in this age group. The peak early and late mitral filling velocities, the early and late velocity-time integral (VTI), the mitral deceleration time, and the atrial filling fraction (late VTI/total VTI) were measured. PAP was obtained from the peak tricuspid regurgitation velocity. Of 252 echocardiograms performed on patients > or = 90 years old, 47 (19%) were normal. The mean +/- SD values were: ratio of peak early and late mitral filling velocities, 0.69 +/- 0.16; deceleration time, 240 milliseconds +/- 31; ratio of early and late VTI, 1.0 +/- 0.3; atrial filling fraction, 47% +/- 7; and PAP, 31 mm Hg +/- 6. Left ventricular filling in patients aged 90 to 100 years demonstrates increasingly impaired left ventricular relaxation from patients in their eighth and ninth decades. PAP continues to increase with age and PAP < or = 40 mm Hg in the elderly could be considered normal.
authors.affiliation: Division of Cardiology and Department of Cardiac Ultrasound, Vancouver Hospital, Vancouver, BC, Canada.
authors.forename: Hisham
authors.initials: H
authors.lastname: Dokainish
authors.forename: Kenneth
authors.initials: K
authors.lastname: Gin
authors.forename: Pui-Kee
authors.initials: PK
authors.lastname: Lee
authors.forename: John
authors.initials: J
authors.lastname: Jue
mesh_terms: D000368:Aged; D000369:Aged, 80 and over / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D011651:Pulmonary Artery / Q000502:physiology*; D012016:Reference Values; D016277:Ventricular Function, Left / Q000502:physiology*