title: Fast track recovery of high risk coronary bypass surgery patients.
abstract: OBJECTIVE
  Fast track recovery protocols on younger, low risk patients result in shorter hospital stays and decreased costs. However, data is lacking on the impact of these protocols on high risk patients based on an objective scoring system.
  
  
  METHODS
  In this study, a high risk cohort of patients (EuroSCORE >or=6, n=158) was compared with a low risk cohort of patients (EuroSCORE <6, n=1004) to define the safety and efficacy of fast track recovery among high risk patients. A standard perioperative data is collected prospectively for every patient.
  
  
  RESULTS
  Time to extubation was longer in the high risk group (299+/-253 vs. 232+/-256min; P=0.003), but intensive care unit (ICU) stay (25.6+/-28.7 vs. 21.5+/-9.4h; P=ns), and postoperative length of stay (5.8+/-2.4 vs. 5.6+/-2.7 days; P=ns) was similar when compared with the low risk group. Of the high risk patients 81% were extubated within 6h, 87% were discharged from the intensive care unit within 24h, and 67% were discharged from the hospital within 5 days. Multiple regression analysis showed that any red blood cell transfusion (P=0.02), and cross clamp time >60min (P=0.03) were the predictors of delayed extubation (>or=6h) in the high risk group. The predictors of extended ICU stay were any red blood cell transfusion (P=0.0001), and peripheral vascular disease (P=0.05). Any red blood cell transfusion was the only predictor for mortality (P=0.02) and readmission to the hospital within the first 30 days (P=0.02) in this cohort of patients.
  
  
  CONCLUSIONS
  This study confirms the safety and efficacy of fast track recovery protocol among high risk patients undergoing coronary artery bypass surgery. All patients are basically suitable for fast track recovery and the preoperative risk factors are poor predictors of prolonged ventilation, increased ICU and hospital stay. Red blood cell transfusion is associated with delayed extubation and discharge from the ICU, and increased mortality and hospital readmission rate.
authors.affiliation: Department of Cardiovascular Surgery, Acibadem Kadikoy Hospital, Istanbul, Turkey. cemalhan@superonline.com
authors.forename: Cem
authors.initials: C
authors.lastname: Alhan
authors.forename: Fevzi
authors.initials: F
authors.lastname: Toraman
authors.forename: Esref Hasan
authors.initials: EH
authors.lastname: Karabulut
authors.forename: Sümer
authors.initials: S
authors.lastname: Tarcan
authors.forename: Sinan
authors.initials: S
authors.lastname: Dağdelen
authors.forename: Nevnihal
authors.initials: N
authors.lastname: Eren
authors.forename: Nuri
authors.initials: N
authors.lastname: Cağlar
mesh_terms: D000368:Aged; D001803:Blood Transfusion / Q000706:statistics & numerical data; D002985:Clinical Protocols; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000379:methods / Q000401:mortality / Q000534:rehabilitation*; D003422:Critical Care / Q000379:methods; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000209:etiology; D011379:Prognosis; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors