[Indices of humoral and cellular immunity in patients with chronic maxillary sinusitis after the Chernobyl accident].
An evaluation was done of immunological parameters in the post accident period in 41 examined person. Of these, 26 subjects had chronic maxillary sinusitis, 15 were healthy persons (control group). In patients with chronic maxillary sinusitis, the state of the T-system of immunity has been shown to be characterised by a drop in the total count of T-lymphocytes, T-helpers, T-suppresors. Parameters for humoral immunity are characterised by elevation of the peripheral blood levels of B-lymphocytes, prominent disimmunoglobulinaemia--significant reduction of class G immunoglobulins and macroglobulins. The T-cells-helpers ratio is significantly reduced both in group I and group II. Reduction has been ascertained in the ratio of those T-cells-suppressors blocking antibody formation by B-lymphocytes. In patients after the Chernobyl accident, there was noted a significant decline in the functional activity of macrophages.
Tymchenko
A S
AS
Shkoba
Ia V
IaV
Produsevych
L V
LV
Markitan
T V
TV
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation / Q000276:immunology* / Q000528:radiation effects; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology* / Q000528:radiation effects; D008297:Male; D015523:Maxillary Sinusitis / Q000209:etiology / Q000276:immunology*; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D011210:Power Plants; D018788:Radioactive Hazard Release; D016176:T-Lymphocyte Subsets / Q000276:immunology / Q000528:radiation effects; D014455:Ukraine