title: [Histological study of the local-regional invasion of pyriform sinus carcinoma].
abstract: OBJECTIVE
  In order to offer the basis for the operation of the pyriform sinus carcinoma, the local-regional invasion patterns of the pyriform sinus carcinoma were investigated.
  
  
  METHODS
  Twenty-six surgical specimens obtained from patients who undergone laryngopharyngectomy were subjected to a whole organ section study.
  
  
  RESULTS
  Tumors located in the lateral wall of the pyriform sinus spread mainly towards the lateral wall of the hypopharynx. Tumors located in the inner wall of the pyriform sinus spread mainly towards the larynx and opposite side pyriform sinus, the paraglottic space and thyroid cartilage were particularly frequent invaded. It was rare of the invading of the cricoid cartilage. The invasion of the epiglottis and preepiglottic space across the midline had not been found. There were two invading routines, the paraglottic space and preepiglottic space. The invasion of the paraglottic space was through the aryepiglottic fold and the inner surface of the thyroid cartilage. The invading of the preepiglottic space was through the aryepiglottic fold and the upper part of the inner surface of the thyroid cartilage.
  
  
  CONCLUSIONS
  The invading of the preepiglottic space was not the contraindication of the partial laryngectomy. It is practicable to preserve the laryngeal function in most of the patients while tumors located on the lateral or inner wall of the pyriform sinus. There was a tendency to the invading to the contralateral side in the inner wall of the pyriform or postcricoidarytenoid region. Attention should be paid to the submucosal spreading in the postcricoidarytenoid region.
authors.affiliation: Department of Head and Neck Surgery, Shandong Tumor Hospital and Institute, Jinan 250117, China.
authors.forename: J
authors.initials: J
authors.lastname: Fang
authors.forename: X
authors.initials: X
authors.lastname: Wei
authors.forename: S
authors.initials: S
authors.lastname: Cai
authors.forename: L
authors.initials: L
authors.lastname: Sun
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Zhou
authors.forename: S
authors.initials: S
authors.lastname: Liang
authors.forename: X
authors.initials: X
authors.lastname: Luan
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010610:Pharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery