title: [Mechanical research on effects of yishenqing on membranous nephropathy].
abstract: OBJECTIVE
  To investigate the therapeutic effect and mechanism of Yishenqing on rabbit membranous nephropathy.
  
  
  METHODS
  The rabbit membranous nephropathy model was induced by cationic bovine serum albumin, and the immunity of mice together with urine volume and haemorheological property of rats were also estimated.
  
  
  RESULTS
  Yishenqing could significantly reduce the urinary protein content, preserve the renal function and pathologically restore the glomeruli. Moreover, its effects also include immunity enhancement, diuretic property and blood stasis amelioration.
  
  
  CONCLUSIONS
  Yishenqing has good effects on the rabbit membranous nephropathy, which is probably due to the effects of diuretic property, immunity enhancement and blood stasis amelioration.
authors.affiliation: Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Science, Peking University 100083, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Song
authors.forename: Jian
authors.initials: J
authors.lastname: Ma
authors.forename: Chang-ling
authors.initials: CL
authors.lastname: Li
mesh_terms: D000818:Animals; D004232:Diuretics / Q000494:pharmacology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004232:Diuretics; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal