title: [POEMS syndrome: imaging of skeletal manifestations, a study of 8 cases].
abstract: OBJECTIVE
  To describe the imaging features of POEMS, and to compare our experience of 8 cases to a review of literature.
  
  
  METHODS
  This retrospective study included 8 patients (6 men, 2 women) with POEMS. Plain radiographs (8 patients), CT (6), MR (2) were performed.
  
  
  RESULTS
  Topographic localizations of POEMS were pelvis (7 cases), spine (5), femur (1), humerus (1), rib cage (1). Focal bone lesions, multiple (5 cases) or solitary (3 cases), were sclerotic in 4 cases, mixed lytic-sclerotic (lytic center and sclerotic rim) in 3 cases and one patient had an osteolytic lesion with sclerotic margins associated with many osteosclerotic lesions. Profilerative osseous changes were seen in 4 cases (pelvis, spine, tibia). MR imaging was performed in 2 patients: in one patient MR imaging revealed areas of low signal intensity on spin echo T1- and T2-weighted images in vertebral bodies, the other showed a lesion of low signal intensity on spin echo T1-weighted and high signal intensity on T2-weighted images in the ilium and adjacent soft tissue.
  
  
  CONCLUSIONS
  The imaging features commonly observed in POEMS syndrome are sclerotic and mixed lytic-sclerotic lesions, particularly in the pelvis and spine. Proliferative new bone formation is detected in 50%. MR imaging correlates with ostesclerotic or mixed lytic-sclerotic appearance.
authors.affiliation: Service de Radiologie GM St-Jacques, Paris.
authors.forename: J L
authors.initials: JL
authors.lastname: Michel
authors.forename: A S
authors.initials: AS
authors.lastname: Gaucher-Hugel
authors.forename: C
authors.initials: C
authors.lastname: Reynier
authors.forename: A
authors.initials: A
authors.lastname: Lhoste
authors.forename: P
authors.initials: P
authors.lastname: Philippe
authors.forename: O
authors.initials: O
authors.lastname: Aumaitre
authors.forename: J C
authors.initials: JC
authors.lastname: Piette
authors.forename: M
authors.initials: M
authors.lastname: Soubrier
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis; D001842:Bone and Bones / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis; D010014:Osteolysis / Q000175:diagnosis; D010026:Osteosclerosis / Q000175:diagnosis; D016878:POEMS Syndrome / Q000175:diagnosis*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed