title: [Effects of fermented Cordyceps powder on pulmonary function in sensitized guinea pigs and airway inflammation in sensitized rats].
abstract: OBJECTIVE
  To study Cordyceps (artificial fermented Cordyceps sinensis(Berk.) Sacc) powderin the treatment of asthma in the animal models.
  
  
  METHODS
  Pulmonary function and airway inflammation in vivo were investigated.
  
  
  RESULTS
  Cordyceps, 5g.kg-1(ig), significantly inhibited bronchial challenge of ovalbumin-induced change of RL and Cdyn (P < 0.05) and inhibited antigen-induced increase of eosinophils in the BALF of rats (P < 0.05).
  
  
  CONCLUSIONS
  The results suggested cordyceps could be applied for the prevention and cure of asthma.
authors.affiliation: Zhejiang Respiratory Drugs Research Laboratory of State Drugs Administration of China, Zhejiang University College of Medicine, Hangzhou 310031, Zhejiang, China.
authors.forename: X X
authors.initials: XX
authors.lastname: Lin
authors.forename: Q M
authors.initials: QM
authors.lastname: Xie
authors.forename: W H
authors.initials: WH
authors.lastname: Shen
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000403:Airway Resistance / Q000187:drug effects; D000818:Animals; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D032661:Cordyceps / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D007915:Lepidoptera / Q000737:chemistry; D008168:Lung / Q000503:physiopathology*; D008170:Lung Compliance / Q000187:drug effects; D008297:Male; D008517:Phytotherapy; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal