Effects of lycorine on growth and effects of L-galactonic acid-gamma-lactone on ascorbic acid biosynthesis in strains of Cryptococcus laurentii isolated from Narcissus pseudonarcissus roots and bulbs.
The alkaloid lycorine, which is considered to inhibit the last step in ascorbic acid biosynthesis, is produced by Narcissus pseudonarcissus. The growth of two strains (C1 and C3) of Cryptococcus laurentii isolated from root tips of N. pseudonarcissus is inhibited by lycorine, as is the in vivo production of ascorbic acid from L-galactonic acid-gamma-lactone. In contrast, C. laurentii strain C4, isolated from the lycorine-containing bracts of the bulb, was not inhibited by lycorine and did not contain ascorbic acid when cultivated with or without L-galactonic acid-gamma-lactone.
Onofri
Silvano
S
Dipartimento di Scienze Ambientali, Università della Tuscia, Via S. Camillo de Lellis, 01100 Viterbo, Italy.
Barreca
Donatella
D
Garuccio
Isabella
I
D047151:Amaryllidaceae Alkaloids; D001205:Ascorbic Acid / Q000096:biosynthesis*; D015169:Colony Count, Microbial; D003454:Cryptococcus / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification / Q000378:metabolism; D003470:Culture Media; D015966:Gene Expression Regulation, Fungal; D007783:Lactones / Q000378:metabolism / Q000494:pharmacology*; D031427:Narcissus / Q000382:microbiology*; D010617:Phenanthridines / Q000378:metabolism / Q000494:pharmacology*; D018517:Plant Roots / Q000382:microbiology; D018514:Plant Structures / Q000382:microbiology; D013400:Sugar Acids / Q000378:metabolism
D047151:Amaryllidaceae Alkaloids; D003470:Culture Media; D007783:Lactones; D010617:Phenanthridines; D013400:Sugar Acids; C012991:galactonic acid; C015330:lycorine; D001205:Ascorbic Acid