In-vitro evaluation of Perasafe compared with 2% alkaline glutaraldehyde against Mycobacterium spp.
Quantitative suspension and carrier tests were used to compare the activity of Perasafe and Cidex against Mycobacterium tuberculosis, Mycobacterium avium-intracellulare, Mycobacterium fortuitum, and Mycobacterium chelonae. The interference of an organic load, and of hard water was also considered. Both agents achieved reductions exceeding 10(5)-fold within 20 and 30 min for all the strains tested. Perasafe is thus mycobactericidal and a viable alternative to Cidex for intermediate or high-level disinfection.
Hernández
A
A
Departamento de Genética y Microbiología, Facultad de Medicina, Servicio de Microbiología, Hospital Universitari Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, Spain.
Martró
E
E
Matas
L
L
Ausina
V
V
D003428:Cross Infection / Q000517:prevention & control; D004202:Disinfectants / Q000494:pharmacology*; D005976:Glutaral / Q000494:pharmacology*; D006801:Humans; D017053:Infection Control / Q000379:methods; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000145:classification / Q000187:drug effects*; D010463:Peracetic Acid / Q000494:pharmacology*
D004202:Disinfectants; D010463:Peracetic Acid; D005976:Glutaral