title: Male breast cancer.
abstract: OBJECTIVE
  To review cases of male breast cancer.
  
  
  METHODS
  Histopathology Section, Department of Pathology, The Aga Khan University, Karachi.
  
  
  METHODS
  Fifty one cases of male breast cancer specimens, received during a period of 10 years, routinely processed and stained with Haematoxylin and Eosin were analyzed. Special stains and Immunohistochemistry were used in difficult cases.
  
  
  RESULTS
  Male breast cancer affected individuals in the sixth and seventh decades of life with a mean age of 56.2 years. Infiltrating ductal carcinoma (IDC) was the predominant type. Skin involvement was seen in 27.45% of the cases. Breast lump was the most common presenting symptom followed by skin ulceration. At the time of presentation 43.13% patients had a tumour size of more than 3 cm.
  
  
  CONCLUSIONS
  Male breast cancer is a rare disease. Most of our findings correspond to the published local and international data.
authors.affiliation: Department of Pathology, The Aga Khan University Medical Center, Karachi.
authors.forename: N
authors.initials: N
authors.lastname: Kayani
authors.forename: M N
authors.initials: MN
authors.lastname: Khan
authors.forename: Y
authors.initials: Y
authors.lastname: Bhurgri
authors.forename: S
authors.initials: S
authors.lastname: Gill
authors.forename: M I
authors.initials: MI
authors.lastname: Nasir
authors.forename: T
authors.initials: T
authors.lastname: Siddiqui
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018567:Breast Neoplasms, Male / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies