[Molecular epidemiology of respiratory syncytial virus infection in infants].
OBJECTIVE
To search for the molecular epidemiology of respiratory syncytial virus (RSV) infection in infants.


METHODS
The randomly amplified polymorphism DNA (RAPD) technology was used to study 96 RSV strains isolated and identified from the patients in Changchun State Hospital of Pediatrics during 1992-1994 and 1 reference strain of M type.


RESULTS
All strains were typable, four RAPD patterns were observed, different diseases have different types. 87.14% of the patients' RSV strains had the same RAPD pattern(R1).


CONCLUSIONS
RAPD method is a rapid, easy and high resolution technique, with which we can know on the molecular level the microbial infection state. There was epidemic of R1 type infection during the period surveyed.
Sun
L
L
Changchun State Hospital of Pediatrics, ChangChun 130061.
Jiao
L
L
Wang
C
C
D001990:Bronchiolitis, Viral / Q000821:virology*; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017720:Molecular Epidemiology; D011024:Pneumonia, Viral / Q000821:virology*; D019105:Random Amplified Polymorphic DNA Technique; D018357:Respiratory Syncytial Virus Infections / Q000453:epidemiology* / Q000821:virology; D018113:Respiratory Syncytial Virus, Human / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000821:virology*