title: [Multiple factors analysis of intraoperative bleeding and recurrence of juvenile nasopharyngeal angiofibromas].
abstract: OBJECTIVE
  To study the effect of surgical treatment of juvenile nasopharyngeal angiofibromas and the factors influencing intra-operative bleeding and recurrence.
  
  
  METHODS
  Thirty-four patients with juvenile nasopharyngeal angiofibromas treated surgically in Chinese PLA General Hospital between 1986 and 1999 were studied retrospectively. The relationship between surgical treatment, intraoperative bleeding, recurrence and age, duration, staging, preoperative treatment, times of previous operation, operative approaches was statistically analyzed.
  
  
  RESULTS
  The tumors were totally resected in 30 patients, and five patients(16.7%) recurred during a mean follow-up of 77 months. The mean recurrence time after operation was 3.2 months (1-6 months). The amount of intraoperative bleeding correlated well with the age, duration, staging, preoperative treatment, and surgical approaches (P < 0.05), but not with times of previous operation (P > 0.05). Recurrence was not correlated with the age, duration, preoperative treatment and surgical approaches (P > 0.05), but correlated with staging (P < 0.05).
  
  
  CONCLUSIONS
  The factors significantly influencing the intraoperative bleeding were the age, duration and staging. Recurrence was correlated with the tumor stages, incomplete resection or the exceedingly malignant activity of the tumor. Radiotherapy, with a dose of 30Gy, is an adjuvant therapy for incompletely resected, or residual tumors.
authors.affiliation: Department of Otorhinolaryngology and Head Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China. lfliu@hotvoice.com
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: R
authors.initials: R
authors.lastname: Wang
authors.forename: D
authors.initials: D
authors.lastname: Huang
authors.forename: D
authors.initials: D
authors.lastname: Han
authors.forename: W
authors.initials: W
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000601:surgery*; D016063:Blood Loss, Surgical; D002648:Child; D005163:Factor Analysis, Statistical; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies