title: Technetium-99m sestamibi in the diagnosis of breast cancer. The Mayagüez Medical Center experience.
abstract: The most successful screening procedures for breast cancer are breast physical examination and mammography. However, mammography has a positive predictive value of 15-30% for nonpalpable malignancy and of 22% for palpable carcinoma; this results in a large number of biopsies on patients with benign lesions. Furthermore, the benefit of mammography in woman with dense breast tissue (< 50 years old) has been questioned. Different studies have shown that Scintimammography with Tc-99m has a high sensitivity and specificity for detecting breast cancer (average of 85% and 89%, respectively), with higher positive predictive value for palpable lesions (89%). We reviewed retrospectively 35 records of patients that had Scintimammography in our institution, and the sensitivity, specificity, positive and negative predictive values were similar to other centers (100%, 76%, 62.5% and 100%, respectively). So, Scintimammography may be a complement for current diagnostic techniques for breast malignancy in our setting.
authors.affiliation: General Surgery Department, Dr. Ramón E. Betances Hospital, Mayaguez Medical Center, Puerto Rico.
authors.forename: J
authors.initials: J
authors.lastname: Farías-Jimenez
authors.forename: A
authors.initials: A
authors.lastname: Rivera
authors.forename: V M
authors.initials: VM
authors.lastname: Carlo
mesh_terms: D001940:Breast / Q000000981:diagnostic imaging; D001941:Breast Diseases / Q000000981:diagnostic imaging; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging*; D003560:Cysts / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging*; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging*; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi