title: Modafinil augmentation of mirtazapine in a failure-to-thrive geriatric inpatient.
abstract: The failure-to-thrive syndrome in geriatric patients is marked by social withdrawal, apathy, depression, anorexia, and cognitive impairment. For therapy to be effective, the treatment plan must target several of theseareas. This case report describes one such course of treatment for a patient with multiple myeloma with failure-to-thrive who was successfully treated with modafinil and mirtazapine. By using combination pharmacotherapy, we were able to achieve immediate results in a gravely ill patient.
authors.affiliation: Wilford Hall Medical Center. schillerstr@uthscsa.edu
authors.forename: Jason E
authors.initials: JE
authors.lastname: Schillerstrom
authors.forename: Jeff S
authors.initials: JS
authors.lastname: Seaman
mesh_terms: D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001559:Benzhydryl Compounds / Q000627:therapeutic use*; D002100:Cachexia / Q000209:etiology* / Q000534:rehabilitation; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000523:psychology* / Q000534:rehabilitation; D004359:Drug Therapy, Combination; D016330:Frail Elderly / Q000523:psychology; D006760:Hospitalization; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D000078785:Mirtazapine; D000077408:Modafinil
chemical_list: D000929:Antidepressive Agents, Tricyclic; D001559:Benzhydryl Compounds; D000697:Central Nervous System Stimulants; D008803:Mianserin; D000078785:Mirtazapine; D000077408:Modafinil