[Temporal lobe epilepsy and complete bilamination of the granule cell layer of the dentate gyrus].
A bilamination involving the whole dentate stratum granulosum associated with a hippocampal sclerosis is reported. This morphological abnormality could be an unusual aspect of granule cell dispersion, plastic change induced by an early post-natal injury, or the the result from a neuronal migration disorder during the embryonic period. Whatever its origin, this bilamination is an abnormality of the hippocampal development which continues during the first years of life.
Rougier
A
A
Laboratoire d'Epileptologie Expérimentale et Clinique, EA 2967, Université Bordeaux 2. alain.rougier@ar-luni.u-bordeaux2.fr
Brana
C
C
Arthaud
S
S
Le Gal La Salle
G
G
D002452:Cell Count; D002675:Child, Preschool; D018891:Dentate Gyrus / Q000473:pathology*; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis*; D005260:Female; D006624:Hippocampus / Q000002:abnormalities; D006801:Humans; D009562:Nissl Bodies / Q000473:pathology*; D012598:Sclerosis / Q000473:pathology