title: [Outbreak of nosocomial urinary tract infections due to a multidrug resistant Pseudomonas aeruginosa].
abstract: An outbreak of a multidrug resistant Pseudomonas aeruginosa including imipenem resistance occurred in the urology intensive care unit at Charles Nicolle Hospital (Tunis). All isolates presented the same antibiotic resistance pattern and were only susceptible to colistin. The epidemic strain was detected in different sites of this unit. Pulsed-field gel electrophoresis after enzymatic restriction using XbaI was performed in order to establish an epidemiologic link between these infections. Genotypic analysis showed two different patterns and the environmental source was identified in both cases. Although the same antibiotype was harbored by all the isolates, two outbreaks occurring in the same period were identified. The strengthening of hygiene measures allowed to stop the outbreak spreading. Since the hospital environment is the major source of Pseudomonas aeruginosa contamination, a continuous surveillance of the patients and the environmental sources is required for the implementation efficient control measures.
authors.affiliation: Laboratoire de microbiologie, hôpital Charles-Nicolle, boulevard du 9-Avril, 1006 Tunis, Tunisie. ilhem.boutiba@rns.tn
authors.forename: I
authors.initials: I
authors.lastname: Boutiba-Ben Boubaker
authors.forename: J
authors.initials: J
authors.lastname: Boukadida
authors.forename: O
authors.initials: O
authors.lastname: Triki
authors.forename: N
authors.initials: N
authors.lastname: Hannachi
authors.forename: S
authors.initials: S
authors.lastname: Ben Redjeb
mesh_terms: D003091:Colistin / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004196:Disease Outbreaks / Q000517:prevention & control; D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D011552:Pseudomonas Infections / Q000453:epidemiology* / Q000517:prevention & control; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics; D014552:Urinary Tract Infections / Q000382:microbiology*
chemical_list: D003091:Colistin