title: Cardiac response to progressive cycle exercise in moderately obese adolescent females.
abstract: OBJECTIVE
  To assess cardiac responses to exercise and cardiac functional capacity in moderately obese adolescent females.
  
  
  METHODS
  Thirteen healthy females (mean age 13.6 +/- 1.5 years) with a body mass index from 30 to 43 kg per m(2) underwent maximal cycle testing. Cardiac responses were measured by Doppler echocardiogram, and gas exchange variables were determined with open circuit spirometry. Data were analyzed by independent Student's t-tests.
  
  
  RESULTS
  Peak oxygen uptake relative to height(3.0) was significantly greater in the obese (570 +/- 90 ml m(-3)) compared to the nonobese controls (485 +/- 60 ml m(-3)). This difference was explained by a higher peak cardiac output (4.50 +/- 1.06 L m(-3) vs. 3.81 +/- 58 L m(-3)) and stroke volume (24 +/- 5 ml m(-3) vs. 19 +/- 3 ml m(-3)) in the obese. Maximal cardiac index was similar in the two groups. There was no evidence of myocardial dysfunction during exercise in either group.
  
  
  CONCLUSIONS
  Low aerobic fitness in obese adolescents as indicated by depressed peak VO(2) per kg body mass and limited endurance performance does not reflect decreased cardiac functional capacity.
authors.affiliation: Department of Pediatrics, Baystate Medical Center, Springfield, Massachusetts 01199, USA. thomas.rowland@bhs.org
authors.forename: Thomas
authors.initials: T
authors.lastname: Rowland
authors.forename: Ruby
authors.initials: R
authors.lastname: Bhargava
authors.forename: Diane
authors.initials: D
authors.lastname: Parslow
authors.forename: Rubina A
authors.initials: RA
authors.lastname: Heptulla
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D002302:Cardiac Output / Q000502:physiology*; D035061:Control Groups; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D009765:Obesity / Q000503:physiopathology*; D013318:Stroke Volume / Q000502:physiology; D011795:Surveys and Questionnaires