title: MRI of the skeleton in prostate cancer staging.
abstract: OBJECTIVE
  To explore the value of MRI in the detection of bone metastases in newly diagnosed prostate cancer.
  
  
  METHODS
  MRI examinations of the axial skeleton in 76 patients with newly diagnosed prostate cancer were reviewed, and the relation of these findings to the serum level of prostate specific antigen (PSA) was examined.
  
  
  RESULTS
  MRI indicated bone metastases in 26/76 patients (34%) in the entire study group, in 4/24 (17%) with serum PSA <20 ng/ml and in 22/52 (42%) with serum PSA >20 ng/ml.
  
  
  CONCLUSIONS
  These results suggest that MRI is a more sensitive indicator of suspected bone metastases than bone scintigraphy in the low range of serum PSA, but less sensitive in the high range. Further studies of MRI and bone scintigraphy in parallel in patients with serum PSA <20 ng/ml are needed to elucidate their relative value in the staging of patients with prostate cancer.
authors.affiliation: Department of Diagnostic Radiology, Umeå University, Sweden. Anders.Rydh@diagrad.umu.se
authors.forename: Anders
authors.initials: A
authors.lastname: Rydh
authors.forename: Magnus
authors.initials: M
authors.lastname: Lundblad
authors.forename: Katrine Riklund
authors.initials: KR
authors.lastname: Ahlström
authors.forename: Björn
authors.initials: B
authors.lastname: Tavelin
authors.forename: Pär
authors.initials: P
authors.lastname: Stattin
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D015331:Cohort Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000473:pathology*; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D017430:Prostate-Specific Antigen