[Clinical observation on treatment of Russula subnigricans poisoning patients by Ganoderma lucidum decoction].
OBJECTIVE
To observe the effect of Ganoderma lucidum decoction in treating Russula subnigricans poisoning (RSP) patients.


METHODS
The 14 patients of RSP in the treated group were treated with GLD (GLD, one dose was prepared by 100 g of Ganoderma lucidum decocted with water to 600 ml), on the base of conventional treatment, and 11 patients received conventional therapy in the previous year were taken as control. The clinical efficacy and parameters in them were compared, including the urine N-acetyl-D-glucosaminidase (NAG, which reflects the injury of kidney), the red blood cell and protein in urine, the alanine transaminase (ALT, which reflects the injury of liver), and the aspartate aminotransferase (AST, which reflects the injury of heart).


RESULTS
A better clinical cure-markedly improving rate was showed in the treated group as compared with the control group, P < 0.01. In the treated group, red blood cell in urine disappeared after 24 hrs treatment in the majority of patients, urinary protein reduced obviously and the other three parameters reached the peak at the 3rd day then lowered gradually. In the control group, all the parameters increased continuously. Comparison between the parameters at corresponding time in the two groups showed significant difference (P < 0.01), those in the treated group were markedly lower than those in the control group respectively.


CONCLUSIONS
GLD has good effect in treating RSP, could obviously lower the fatat rate of RSP.
Xiao
Gui-lin
GL
Xiangya Hospital, Central South University, Changsha 410008.
Liu
Fa-yi
FY
Chen
Zuo-hong
ZH
D000118:Acetylglucosaminidase / Q000652:urine*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000188:drug therapy*; D008517:Phytotherapy; D020940:Reishi / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000118:Acetylglucosaminidase