Post-irradiation polyradiculopathy mimics leptomeningeal tumor on MRI.
Three patients with a remote history of Hodgkin's disease treated with total or subtotal lymphoid radiation 17 to 24 years earlier developed lumbosacral polyradiculopathy associated with nodular meningeal enhancement of the conus medullaris and cauda equina on MRI. None had evidence of recurrent Hodgkin's disease or second malignancy, and the MRI findings may be sequelae of radiation therapy.
Hsia
Amie W
AW
Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94304-0117, USA. ahsia@stanford.edu
Katz
Jonathan S
JS
Hancock
Steven L
SL
Peterson
Kendra
K
D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D015182:Lymphatic Irradiation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000175:diagnosis; D020335:Paraparesis / Q000209:etiology; D011128:Polyradiculopathy / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D011832:Radiation Injuries / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D013117:Spinal Cord Compression / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D013997:Time Factors