Transformation between Kaposiform hemangioendothelioma and tufted angioma.
Kaposiform hemangioendothelioma and tufted angioma are viewed as two separate disease entities in the current classification of vascular tumors. However, the concurrence of features of both vascular tumors in the same specimen of some patients raises the question whether these tumors exist on a continuum. Herein, we report a dynamic transformation between both tumors within a single patient, which suggests they are two variants of the same vascular tumor.
Chu
Chia-Yu
CY
Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan.
Hsiao
Cheng-Hsiang
CH
Chiu
Hsien-Ching
HC
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D001706:Biopsy; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D006390:Hemangioendothelioma / Q000188:drug therapy / Q000473:pathology*; D006392:Hemangioma, Cavernous / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage / Q000009:adverse effects; D008103:Liver Cirrhosis / Q000150:complications; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology*; D011994:Recombinant Proteins; D012514:Sarcoma, Kaposi / Q000188:drug therapy / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins