Germ cell tumors: review of selected studies from 2002.
Testicular cancer remains a major success story in the realm of solid tumors. There are still many remaining challenges in diagnosis, treatment, and prevention of long-term toxicity. Surgery and platinum-based chemotherapy, however, still encompass the main treatment modalities. Attempts to limit toxicity from both surgery and chemotherapy remain at the forefront of research. New chemotherapeutic options are available for patients with platinum-resistant disease, and stem cell transplant remains an area of active study.
Hellerstedt
Beth A
BA
University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Pienta
Kenneth J
KJ
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D018237:Germinoma / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009919:Orchiectomy / Q000379:methods; D011379:Prognosis; D011788:Quality of Life; D018570:Risk Assessment; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D016896:Treatment Outcome