title: Diffuse alopecia in a hemodialysis patient caused by a low-molecular-weight heparin, tinzaparin.
abstract: The authors report on a 66-year-old hemodialysis patient who had diffuse alopecia while on anticoagulation treatment to prevent extracorporeal blood clotting with a low- molecular-weight heparin (LMWH), tinzaparin. The alopecia reversed completely when tinzaparin was substituted by another LMWH, enoxaparin. The biopsy findings, the possible mechanisms of heparin's action in the hair roots, and the restoration of the patient's hairs after the discontinuation of tinzaparin are discussed.
authors.affiliation: Department of Nephrology, Western Attica General Hospital of Athens, Athens, Greece. ESARRIS1_@HOTMAIL.COM
authors.forename: Evangelos
authors.initials: E
authors.lastname: Sarris
authors.forename: Efrosini
authors.initials: E
authors.lastname: Tsele
authors.forename: Giorgia
authors.initials: G
authors.lastname: Bagiatoudi
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Salpigidis
authors.forename: Danai
authors.initials: D
authors.lastname: Stavrianaki
authors.forename: Loukas
authors.initials: L
authors.lastname: Kaklamanis
authors.forename: Marios
authors.initials: M
authors.lastname: Siakotos
mesh_terms: D000368:Aged; D000505:Alopecia / Q000139:chemically induced*; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008297:Male; D006435:Renal Dialysis; D000078222:Tinzaparin
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D000078222:Tinzaparin