Hyperparathyroidism-jaw tumour syndrome.
Amongst hyperparathyroidism-related syndromes, hyperparathyroidism-jaw tumour syndrome is one of the least common and relatively unknown but its clinical and genetic aspects are not less interesting or important. With the recent identification of its genes, we can now better characterize the disease, both clinically and genetically, which will certainly impact the field of endocrinology and oncology. In this article, we review the clinico-pathological features and genetic basis of this syndrome with the hope that it will create awareness and interest in this disease amongst clinicians and basic scientists.
Chen
J D
JD
Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
Morrison
C
C
Zhang
C
C
Kahnoski
K
K
Carpten
J D
JD
Teh
B T
BT
D016147:Genes, Tumor Suppressor; D006801:Humans; D006961:Hyperparathyroidism / Q000235:genetics* / Q000473:pathology; D007573:Jaw Neoplasms / Q000235:genetics* / Q000473:pathology; D007680:Kidney Neoplasms / Q000235:genetics / Q000473:pathology; D008441:Maxillary Neoplasms / Q000235:genetics / Q000473:pathology; D018761:Multiple Endocrine Neoplasia Type 1; D010282:Parathyroid Neoplasms / Q000473:pathology; D013577:Syndrome