Comparing the base usage frequency between bacteria DNA double strand.
During the Evolution, effected by select pressure or nature mutation, the compositions of bacteria genomes is various. And many experiences prove that the genes between leading strand and lagging strand is distinctly in copy, transcription and repair. Some scholars presume that the bases distribution is difference between the two strand, to verify the guess, we using the technology of bioinformatics, compare the base usage between the DNA double strand in 17 species bacteria. The result show: 1. there is same bases usage frequency in coding sequence between leading strand and lagging strand 2. There also same bases usage frequency in first codon, second codon and third codon. It suggest that there is a equilibrium between the two strand by the effect of select pressure and nature mutation.
Zhong
Dong
D
Department of Biochemics, ZhongShan University, Guangzhou 510275, China.
Zhao
Gui-Jun
GJ
Zhang
Zhen-Shu
ZS
Lin
Jiang-Hai
JH
Qin
Tang-Ni
TN
Xu
An-Long
AL
D001419:Bacteria / Q000235:genetics*; D003062:Codon / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics*; D030561:Databases, Nucleic Acid; D019143:Evolution, Molecular; D005798:Genes, Bacterial / Q000235:genetics; D016680:Genome, Bacterial; D009154:Mutation; D009711:Nucleotides / Q000235:genetics; D012641:Selection, Genetic
D003062:Codon; D004269:DNA, Bacterial; D009711:Nucleotides