title: Readily prepared chiral P,N ligands and their applications in cu-catalyzed enantioselective conjugate additions.
abstract: A new type of phosphite-pyridine (P,N) ligand derived from (S)-NOBIN and (S)-BINOL was employed in Cu(I)-catalyzed conjugate addition of diethylzinc to chalcones. The new P,N ligands were highly efficient in the copper-catalyzed enantioselective 1,4-conjugate additions of diethylzinc to acyclic enones, and up to 97% ee was achieved.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, People's Republic of China.
authors.forename: Yuanchun
authors.initials: Y
authors.lastname: Hu
authors.forename: Xinmiao
authors.initials: X
authors.lastname: Liang
authors.forename: Junwei
authors.initials: J
authors.lastname: Wang
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Zheng
authors.forename: Xinquan
authors.initials: X
authors.lastname: Hu