[Effects of antioxidation and ceramide of improved prescription of didang-tang (IPDT) on exprimental atherosclerosis rabbits].
OBJECTIVE
To observe the effects of antioxidation and ceramide content of improved prescription of Didang-tang (IPDT) on exprimental atherosclerosis(AS) rabbits.


METHODS
Plasm Superoxide Dismutase(SOD) activity was detected with micro-content fast detecting method, Plasm Malondialdehyde(MDA) content with improved BaMuGuoFu method, and Aortic Ceramide (CER) content with thinlayer scanning.


RESULTS
IPDT could effectivly improve plasma SOD activity and decrease plasma MDA content and decrease aortic CER content.


CONCLUSIONS
IPDT on exprimental AS is related to the improvement of antioxidation and decrease of CER content.
Huang
He-qing
HQ
Drugs College of Sun Yat-sen University, Guangzhou 510080, Guangdong, China. hhq998@263.sina.com
Tao
Sha
S
Liu
Pei-qing
PQ
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001161:Arteriosclerosis / Q000378:metabolism*; D002518:Ceramides / Q000378:metabolism*; D027424:Cinnamomum / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D007865:Leeches / Q000737:chemistry; D008297:Male; D008419:Materia Medica / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D012250:Rheum / Q000737:chemistry
D000975:Antioxidants; D002518:Ceramides; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica