Intraocular lens tolerance in surgery for cataracta complicata: assessment of four implant materials.
OBJECTIVE
To evaluate various available intraocular lenses (IOL) (PMMA, acrylic, heparin coated PMMA, and silicone) in patients with cataracta complicata and evaluate IOL tolerance, post-operative inflammation, cystoid macular edema, and posterior capsular opacification(PCO) requiring Nd:YAG capsulotomy.


METHODS
randomized, double masked clinical trial.


METHODS
Patients evaluated in the Ocular Immunology and Uveitis Service of the Massachusetts Eye and Ear Infirmary and deemed to need cataract surgery by standard criteria were asked to participate in the clinical trial. Patients had to have a diagnosis of chronic uveitis, which was inactive for 3 months prior to cataract surgery.


RESULTS
Acrylic lenses appeared to provide the best overall results when evaluated for post-operative inflammation, PCO rates, visual acuity, and cystoid macular edema (CME) (compared to PMMA, silicone, and heparin coated PMMA).
Papaliodis
George N
GN
Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Nguyen
Quan Dong
QD
Samson
C Michael
CM
Foster
C Stephen
CS
D000180:Acrylic Resins; D000328:Adult; D000368:Aged; D019923:Capsulorhexis; D002908:Chronic Disease; D020099:Coated Materials, Biocompatible; D004311:Double-Blind Method; D005260:Female; D006493:Heparin; D006801:Humans; D015994:Incidence; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D011446:Prospective Studies; D012826:Silicone Elastomers; D014605:Uveitis / Q000150:complications
D000180:Acrylic Resins; D020099:Coated Materials, Biocompatible; D012826:Silicone Elastomers; D006493:Heparin; D019904:Polymethyl Methacrylate