title: [Progress in the study of physiological function of sphingosine 1-phosphate].
abstract: Sphingosine 1-phosphate, a bioactive sphingolipid produced from the metabolism of sphingomyelin, play important roles in diverse biological process, including cell proliferation, survival, cytoskeleton changes, migration, angiogenesis, wound healing and embryonic development. Here we review the role of sphingosine 1-phosphate in cell biological function regulation and signal transduction.
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850.
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Duan
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Wang
authors.forename: Chutse
authors.initials: C
authors.lastname: Wu
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D006413:Hematopoietic System / Q000502:physiology; D006801:Humans; D008246:Lysophospholipids; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology; D043562:Receptors, G-Protein-Coupled; D049312:Receptors, Lysophospholipid; D015398:Signal Transduction; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000502:physiology*
chemical_list: D008246:Lysophospholipids; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D049312:Receptors, Lysophospholipid; C060506:sphingosine 1-phosphate; D013110:Sphingosine