title: Flavonoids from Andrographis lineata.
abstract: Three flavonoids, 5,7,2',3',4'-pentamethoxyflavone (1), 2'-hydroxy-2,4',6'-tri methoxychalcone (2) and dihydroskullcapflavone I (3), together with 17,19,20-trihydroxy-5beta, 8alpha H, 9beta H,10alpha-labd-13-en-16,15-olactone (4), a known diterpenoid and six known flavonoids, 5-hydroxy-7,8-dimethoxyflavanone (5), 5-hydroxy-7,8,2',3',4'-pentamethoxyflavone (6), 5,2'-dihydroxy-7-methoxyflavanone (7), 5,2'-dihydroxy-7,8-dimethoxyflavone (8), 5,2'-dihydroxy-7-methoxyflavone (9) and 5,2'-dihydroxy-7-methoxyflavone 2'-O-beta-D-glucopyranoside (10) were isolated from the whole plant of Andrographis lineata. The structures of these compounds were elucidated on the basis of spectral and chemical studies.
authors.affiliation: Natural Products Division, Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India.
authors.forename: P Hari
authors.initials: PH
authors.lastname: Kishore
authors.forename: M Vijaya Bhaskar
authors.initials: MV
authors.lastname: Reddy
authors.forename: M Kesava
authors.initials: MK
authors.lastname: Reddy
authors.forename: D
authors.initials: D
authors.lastname: Gunasekar
authors.forename: Cristelle
authors.initials: C
authors.lastname: Caux
authors.forename: Bernard
authors.initials: B
authors.lastname: Bodo
mesh_terms: D035685:Andrographis / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D004224:Diterpenes; D005419:Flavonoids