[Negative selection and computer models of the joint evolution of the patterns of polygenes, transposable elements, and origin identity labels].
Computer simulation of the population dynamics of the genomic patterns of polygenes, transposable elements (TEs), and origin identity labels (OILs) in the course of negative selection for an additive quantitative trait has been performed. It was demonstrated that active polygene alleles disappear very rapidly, whereas the patterns of TEs and OILs continue their evolution determined by strict selective inbreeding and gene drift. Dendrograms of the patterns of polygenes, TEs, and OILs were constructed for all generations. It was demonstrated that the final consensus pattern of OILs consists of the fragments of the original patterns, which contain neither active polygene alleles nor modifier or marker TEs. Neutral TE copies were present in the final pattern, as should be expected in the case of gene drift. Inbreeding coefficient increased steadily but by generation 100 reached values higher than 0.9. All other parameters and initial conditions being the same, the responses to negative and positive selections were asymmetric.
Egorova
A V
AV
Department of Cytology and Genetics, Novosibirsk State University, Novosibirsk, 630090 Russia.
Ratner
V A
VA
Iudanin
A Ia
AIa
D000818:Animals; D005075:Biological Evolution; D003198:Computer Simulation; D004251:DNA Transposable Elements / Q000235:genetics*; D005260:Female; D040961:Genetic Drift; D007178:Inbreeding; D008297:Male; D011157:Population Dynamics; D019655:Quantitative Trait, Heritable; D012641:Selection, Genetic
D004251:DNA Transposable Elements