title: Associations between psychological profiles and diseases: examining hemispheric dominance and autonomic activation as underlying regulators.
abstract: Personality profiles are often typical for specific illnesses, e.g., the type A personality and heart disease. We hypothesize that many more such patterns exist, and have developed a scheme in which many diseases can be classified, depending on hemispheric dominance (i.e., integrated, intellectualising or emotional) and type of autonomic control (i.e., dominance of either sympathetic or parasympathetic system, or an increase in both types of autonomic outflow). Our hypothesis is based on recent findings in neurophysiology, involving the early rearing environmental effects on the developing orbitofrontal cortex, and attachment theory. We conclude with implications for therapy, and a discussion of the limitations of our hypothesis.
authors.affiliation: Department of Physiology, University of Pretoria, Pretoria, South Africa.
authors.forename: A
authors.initials: A
authors.lastname: Panzer
authors.forename: M
authors.initials: M
authors.lastname: Viljoen
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D002540:Cerebral Cortex / Q000502:physiology*; D004194:Disease / Q000209:etiology; D004292:Dominance, Cerebral / Q000502:physiology*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008954:Models, Biological; D009482:Neurophysiology; D010551:Personality