title: An integral view of the neuroendocrine aspects of male sexual dysfunction and aging.
abstract: Age is the most important factor associated with sexual dysfunction. The traditional thinking explained this association by the neurovascular events developing with the aging process. More recently, central neuro-endocrine mechanisms resulting from apoptosis in the hypothalamic areas involved in both the production of sex hormones and the control of sexual processes have added a new dimension to human sexuality. This evidence is still controversial but of unquestionable importance in our understanding of endocrine alterations and sexual shortcomings associated with aging.
authors.affiliation: Department of Urology, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Morales
mesh_terms: D000375:Aging / Q000502:physiology*; D007172:Erectile Dysfunction / Q000503:physiopathology; D012739:Gonadal Steroid Hormones / Q000096:biosynthesis / Q000502:physiology; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D010410:Penile Erection / Q000502:physiology*; D012735:Sexual Dysfunction, Physiological / Q000503:physiopathology*
chemical_list: D012739:Gonadal Steroid Hormones