title: Choroiditis in systemic lupus erythematosus: systemic steroid therapy and focal laser treatment.
abstract: OBJECTIVE
  To report a rare case of choroiditis in association with systemic lupus erythematosus (SLE).
  
  
  METHODS
  A 49-year-old woman with a 17-year history of SLE experienced acute vision impairment of her left eye during the remission stage of systemic SLE. Fundus examination revealed a gray-white subretinal exudate with serous retinal detachment. Angiographic examination disclosed choroidal inflammation at the macula and a breakdown of the blood retinal barrier. Retinal burns were applied to the subretinal exudate with an argon laser as in the treatment of central serous retinopathy. Afterward, her visual acuity showed prompt recovery due to the regression of the serous retinal detachment. However, the choroidal inflammation remained until the systemic condition was controlled with steroid therapy.
  
  
  RESULTS
  Laser treatment of a subretinal exudate was helpful for the resolution of serous detachment and the prompt improvement of visual acuity, whereas systemic steroid therapy was effective for choroidal inflammation.
  
  
  CONCLUSIONS
  Systemic steroid therapy is thought to be effective for SLE choroiditis; however, this therapy is also known to cause serous retinal detachment. Thus, in SLE choroiditis, laser photocoagulation at a leakage point, in addition to systemic steroid therapy, may be helpful for the prompt restoration of vision in patients with serous retinal detachment.
authors.affiliation: Department of Ophthalmology, Tohoku University, School of Medicine, Sendai, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Shimura
authors.forename: Yuko
authors.initials: Y
authors.lastname: Tatehana
authors.forename: Kanako
authors.initials: K
authors.lastname: Yasuda
authors.forename: Shin ichiro
authors.initials: Si
authors.lastname: Saito
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sasaki
authors.forename: Makoto
authors.initials: M
authors.lastname: Tamai
mesh_terms: D001813:Blood-Retinal Barrier; D002199:Capillary Permeability; D002833:Choroiditis / Q000188:drug therapy* / Q000209:etiology; D004396:Coloring Agents; D003131:Combined Modality Therapy; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007208:Indocyanine Green; D017075:Laser Coagulation; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D005938:Glucocorticoids; D007208:Indocyanine Green; D011241:Prednisone