Successful treatment of multiple filiform facial warts with imiquimod 5% cream in a patient infected by human immunodeficiency virus.
Imiquimod, an imidazoquinoline amine, is approved for the topical treatment of external anogenital warts induced by human papilloma virus. Several clinical trials have shown imiquimod to be an effective and safe drug for treatment of anogenital warts. Consequently, it was considered that imiquimod might be effective on warts caused by the same aetiological agent located on other skin areas. We describe the favourable outcome of a case of multiple facial verrucae in a human immunodeficiency virus (HIV)-infected patient treated with imiquimod 5% cream. This is a promising finding which supports those of two previous reports. We feel that imiquimod could be used in HIV-infected patients with multiple facial warts in whom conventional therapies are ineffective or produce significant side-effects.
Hagman
J H
JH
Department of Dermatology, University of Rome Tor Vergata, Rome, Italy.
Bianchi
L
L
Marulli
G C
GC
Soda
R
R
Chimenti
S
S
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000473:pathology; D000328:Adult; D000634:Aminoquinolines / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use; D005148:Facial Dermatoses / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D007369:Interferon Inducers / Q000627:therapeutic use*; D008297:Male; D014860:Warts / Q000188:drug therapy* / Q000473:pathology
D000634:Aminoquinolines; D000998:Antiviral Agents; D007369:Interferon Inducers; D000077271:Imiquimod