[The role of reaper-dependent apoptosis in radiation-induced life-span alterations in Drosophila melanogaster].
This is the result of studying on a problem of radio-induced ageing. From the point of view of radiation genetics it is perspective to investigate influence of low doze irradiation on individuals with the mutant phenotypes that allows to assume a role of separate genes and mechanisms controllable by them in determination of life span and ageing. The role of a reaper-dependent way of apoptosis regulation in the induced change of life span is shown. The assumption is put forward that apoptosis has the important role during ageing an animal organism.
Moskalev
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AA
Institute of Biology, Komi Scientific Center, Ural Division of Russian Academy of Science, Syktyvkar, 167982 Russia. moskalev@ib.komisc.ru
Zaĭnullin
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VG
D000375:Aging / Q000235:genetics / Q000528:radiation effects*; D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000528:radiation effects*; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology* / Q000528:radiation effects*; D005720:Gamma Rays; D017344:Genes, Insect; D008297:Male; D008954:Models, Biological; D009154:Mutation; D010641:Phenotype; D011829:Radiation Dosage; D011831:Radiation Genetics; D013997:Time Factors
D029721:Drosophila Proteins; C086973:rpr protein, Drosophila