Does asbestos cause laryngeal cancer?
Asbestos is a known carcinogen. Its role in the aetiology of laryngeal cancer has been investigated and debated for the last three decades. Here, we consider much of the published evidence from post-mortem studies, cross-sectional, case-control and cohort studies. We feel that the weight of evidence does not support a causal association for asbestos with laryngeal cancer. The 'positive studies' raise important questions regarding an association; the opportunity may present itself to answer some of these as the incidence of asbestos-related malignancy is increasing in the UK and Europe.
Griffiths
H
H
Russells Hall Hospital, Dudley, West Midlands, UK. huwgriffiths.1@btinternet.com
Molony
N C
NC
Malony
N C
NC
D001194:Asbestos / Q000009:adverse effects*; D017636:Asbestos, Amphibole / Q000009:adverse effects; D002273:Carcinogens / Q000009:adverse effects*; D016022:Case-Control Studies; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D012107:Research Design / Q000592:standards; D012907:Smoking / Q000009:adverse effects
D017636:Asbestos, Amphibole; D002273:Carcinogens; D001194:Asbestos