Easy access to novel substituted 6-aminoimidazo[1,2-a]pyridines using palladium- and copper-catalyzed aminations.
Convenient and efficient methods for the preparation of novel 6-aminoimidazo[1,2-a]pyridine derivatives are reported that utilized palladium- or copper-catalyzed methodology. The crystal structure for 6-N-methylanilinoimidazo[1,2-a]pyridine 10 is also described.
Enguehard
Cécile
C
EA 3247, Laboratoire de Chimie Thérapeutique, Laboratoire de Chimie Physique, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Allouchi
Hassan
H
Gueiffier
Alain
A
Buchwald
Stephen L
SL
D000586:Amination; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis*
D007093:Imidazoles; D007202:Indicators and Reagents; D011725:Pyridines; D010165:Palladium; D003300:Copper