title: Thyroid hormone-induced sulfate absorption in Aplysia californica gut is mediated by protein synthesis.
abstract: Mucosal membranes of foregut epithelia of Aplysia californica contain a sodium-sulfate symporter that is stimulated by triiodothyronine. Actinomycin D, puromycin, or cycloheximide inhibited the triiodothyronine-stimulated sulfate absorption. It appears that thyroid hormone manifests its effects on sulfate absorption in the A. californica gut through protein synthesis.
authors.affiliation: Department of Physiology & Functional Genomics, College of Medicine, Box 100274 JHMHC, University of Florida, Gainesville, FL 32610, USA. gag@phys.med.ufl.edu
authors.forename: George A
authors.initials: GA
authors.lastname: Gerencser
authors.forename: Stanley Y
authors.initials: SY
authors.lastname: Loo
authors.forename: Jianliang
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001048:Aplysia / Q000378:metabolism*; D025461:Feedback, Physiological / Q000187:drug effects / Q000502:physiology; D007408:Intestinal Absorption / Q000187:drug effects* / Q000502:physiology; D007413:Intestinal Mucosa / Q000187:drug effects* / Q000502:physiology*; D014176:Protein Biosynthesis; D013431:Sulfates / Q000378:metabolism*; D027981:Symporters / Q000187:drug effects / Q000378:metabolism; D014284:Triiodothyronine / Q000494:pharmacology*
chemical_list: D013431:Sulfates; D027981:Symporters; D014284:Triiodothyronine