Presence of atrial natriuretic factor in normal and hyperplastic human prostate and its relationship with oxytocin localisation.
In this work, we showed the presence of atrial natriuretic factor (ANF) in human prostate and compared its localisation in normal and hyperplastic conditions. ANF was localised in epithelial and stromal cells, being increased in hyperplasia, mainly in the stromal component. Moreover, we compared ANF and oxytocin positivity in the same glands, focusing on the possible relationship between the paracrine effects of these two hormones.
Farina-Lipari
E
E
Human Anatomy Section, Department of Experimental Medicine, via del Vespro 129, 90127 Palermo, Italy. farina.elviravitt@tiscalinet.it
Lipari
D
D
Bellafiore
M
M
Anzalone
R
R
Cappello
F
F
Valentino
B
B
D009320:Atrial Natriuretic Factor / Q000378:metabolism*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D010121:Oxytocin / Q000378:metabolism; D011467:Prostate / Q000033:anatomy & histology / Q000378:metabolism* / Q000473:pathology; D011469:Prostatic Diseases / Q000378:metabolism* / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000378:metabolism* / Q000473:pathology; D017154:Stromal Cells / Q000378:metabolism / Q000473:pathology
D010121:Oxytocin; D009320:Atrial Natriuretic Factor