Does preoperative paresis influence intraoperative monitoring of the motor cortex?
Intraoperative monitoring of motor function by means of motor evoked potentials (MEPs) is a new method. The current study examines the influence of preoperative paresis on the feasibility and reliability of this method. Intraoperative monitoring of MEPs was performed in 58 patients during surgery in the central region. The patients were divided into three groups according to their preoperative strength (group I, muscle strength less than or equal to grade 4 according to the British Medical Research Council grading system [n = 17]; group II, normal strength (n = 36); and group III, muscle strength less than grade 5 but not worse than grade 4 [n = 5]). The motor cortex was stimulated directly with a high-frequency monopolar anodal train. In groups II and III, MEPs were elicited in all patients on cortical stimulation, whereas in group I a response was obtained in only 88% of patients. The MEP parameters in all groups had a broad interindividual range of variation. A correlation between individual intraoperative potential changes and surgical maneuvers was observed in seven patients in group II and in four patients in group I. No MEP changes were recorded in group III. Irreversible MEP changes (groups I and II) resulted in postoperative clinical deterioration. No postoperative deterioration of motor function was observed in patients with reversible MEP changes. Preoperative paresis reduces the feasibility of the method; however, it has no influence on the intraoperative pattern and reaction of the MEPs.
Kombos
Theodoros
T
Neurochirurgische Klinik, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Germany. kombos@medizin.fu-berlin.de
Kopetsch
Olaf
O
Suess
Olaf
O
Brock
Mario
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D019054:Evoked Potentials, Motor; D005073:Evoked Potentials, Somatosensory; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D009044:Motor Cortex / Q000503:physiopathology*; D010291:Paresis / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D011237:Predictive Value of Tests; D011300:Preoperative Care; D011786:Quality Control; D015203:Reproducibility of Results; D016896:Treatment Outcome