title: Spontaneous fatal intracranial hemorrhage in a child with Evans syndrome.
abstract: Evans syndrome is a chronic and recurrent disease often resistant to multiagent therapy. Spontaneous intracranial hemorrhage is a rare but life-threatening complication in children with Evans syndrome. The authors report the fatal course of a child with chronic thrombocytopenia who presented a spontaneous intracranial hemorrhage. The case indicates that this potentially fatal event may occur even in children with a moderate grade of chronic thrombocytopenia. Early recognition and aggressive management is required for an adequate management of this rare complication.
authors.affiliation: Division of Pediatric Oncology, Catholic University of Rome, Rome, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ruggiero
authors.forename: Marco
authors.initials: M
authors.lastname: Piastra
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Casadei Pistilli
authors.forename: Sara
authors.initials: S
authors.lastname: Serretti
authors.forename: Werner
authors.initials: W
authors.lastname: Beate
authors.forename: Antonio
authors.initials: A
authors.lastname: Chiaretti
authors.forename: Riccardo
authors.initials: R
authors.lastname: Riccardi
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D006406:Hematoma / Q000000981:diagnostic imaging; D006801:Humans; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D010976:Platelet Count; D011696:Purpura, Thrombocytopenic / Q000150:complications / Q000175:diagnosis*; D011859:Radiography; D013577:Syndrome