Foamy macrophages in the liver of cattle fed Brachiaria brizantha hay.
Liver and lymph nodes injuries characterized by clusters of foamy macrophages, some of them containing birefringent crystals, were observed in cattle fed on Brachiaria brizantha hay. The cattle were from an experimental group poisoned with Senecio brasiliensis known to cause hepatic fibrosis and hepatocyte megalocytosis. One of the animals developed photosensitivity but the exact cause wasn't determined since both plants were fed. The foamy macrophages were present from the 30th d of feeding. Early appearance of these lesions may be particular to the animal specie used or due to the presence of both toxic plants.
Torres
Márcia Bersane Araújo de Medeiros
MB
Departamento de Medicina Veterinária da Universidade Federal do Paraná, UFPR, Campus Palotina, Palotina, PR, Brasil.
Coelho
Kunie Iabuki Rabello
KI
D000818:Animals; D035201:Brachiaria / Q000506:poisoning*; D002417:Cattle; D002418:Cattle Diseases / Q000139:chemically induced* / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D005487:Foam Cells / Q000187:drug effects / Q000648:ultrastructure; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008264:Macrophages / Q000187:drug effects / Q000648:ultrastructure; D010939:Plant Poisoning / Q000209:etiology / Q000662:veterinary*