title: Does adenotonsillectomy improve growth in children with obstructive adenotonsillar hypertrophy?
abstract: Faltering growth may be associated with adenotonsillar hypertrophy, but its pathophysiological mechanism is unclear. This study included 29 pre-pubertal children with obstructive adenotonsillar hypertrophy, and aimed to investigate the probable difference in energy intake and serum insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3) levels before and 6 months after adenotonsillectomy. Weight and height standard deviation scores, energy intake per kilogram and serum IGF-1 levels were found to be significantly higher 6 months after adenotonsillectomy, indicating that adenotonsillar hypertrophy is associated with poor growth.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Atatürk University, Erzurum, Turkey. erolselimoglu@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Selimoğlu
authors.forename: M A
authors.initials: MA
authors.lastname: Selimoğlu
authors.forename: Z
authors.initials: Z
authors.lastname: Orbak
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology; D001827:Body Height; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D002149:Energy Intake; D005260:Female; D006128:Growth; D006130:Growth Disorders / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D006984:Hypertrophy / Q000150:complications / Q000601:surgery; D018972:Insulin-Like Growth Factor Binding Protein 3 / Q000097:blood* / Q000378:metabolism; D007334:Insulin-Like Growth Factor I / Q000032:analysis* / Q000378:metabolism; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000378:metabolism* / Q000601:surgery*; D014068:Tonsillectomy; D016896:Treatment Outcome
chemical_list: D018972:Insulin-Like Growth Factor Binding Protein 3; D007334:Insulin-Like Growth Factor I