title: [Phase-contrast x-ray imaging with x-ray interferometer for medical applications].
abstract: Phase-contrast x-ray imaging with x-ray interferometer can depict the minute difference within the biological object, and its sensitivity is about 1000 times higher than that of absorption-contrast method. For biomedical use of this technique, a large monolithic x-ray interferometer and 2 crystal interferometer having a field of view with 25 mm x 25 mm is being developed. Phase-contrast x-ray CT could reveal detail structures within tumor and surrounded tissue, and the vessel imaging of rat liver is also possible using physiological saline at 17.7 keV x-ray energy. Recently, human breast tissues were imaged at 35 keV and the contrast of image was much better than usual absorption contrast x-ray image obtained at 17.7 keV energy.
authors.affiliation: Institute of Clinical Medicine, University of Tsukuba, Japan. ttakeda@md.tsukuba.ac.jp
authors.forename: Tohoru
authors.initials: T
authors.lastname: Takeda
authors.forename: Akio
authors.initials: A
authors.lastname: Yoneyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Momose
authors.forename: Jin
authors.initials: J
authors.lastname: Wu
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Zeniya
authors.forename: Thet-Thet
authors.initials: TT
authors.lastname: Lwin
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tsuchiya
authors.forename: Donepudi V
authors.initials: DV
authors.lastname: Rao
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Hyodo
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hirano
authors.forename: Yuji
authors.initials: Y
authors.lastname: Aiyoshi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Itai
mesh_terms: D000818:Animals; D006801:Humans; D008327:Mammography / Q000295:instrumentation / Q000379:methods; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000295:instrumentation* / Q000379:methods; D051381:Rats; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods