title: [Clinical comparison between guided tissue regeneration and induced tissue regeneration].
abstract: OBJECTIVE
  The aim of the present study was to evaluate, over a period of 1 y, 3 different surgical methods for the treatment of periodontal bone defects.
  
  
  METHODS
  Thirty-six infrabone defects, at least 4 mm in depth, in non-smokers were enrolled in the study. Of these, 12 were treated with guided tissue regeneration (GTR) using a resorbable membrane with collagen, 12 with enamel matrix derivative (EMD) gel and 12 with a modified Widman flap (MWF). The pocket depth, attachment loss and gingival recession both before commencement of therapy and after an interval of 1 y are reported.
  
  
  RESULTS
  The reduction in pocket depth was 4 mm, 4.4 mm, and 4.5 mm, respectively, for the control group, GTR group and EMD group. The attachment gain for the respective treatments was: MWF, 2 mm; GTR, 2.8 mm; EMD, 2.9 mm. Gingival recession was: MWF, 1.8 mm; GTR, 1.5 mm; EMD, 1.1 mm.
  
  
  CONCLUSIONS
  These findings show the efficacy of the 3 methods in the treatment of bone defects, but none of the 3 emerges as being statistically superior to the others 2.
authors.affiliation: Cattedra di Parodontologia, Università degli Studi di Modena e Reggio Emilia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Forabosco
authors.forename: S
authors.initials: S
authors.lastname: Spinato
authors.forename: S
authors.initials: S
authors.lastname: Diacci
authors.forename: A
authors.initials: A
authors.lastname: Grippo
mesh_terms: D000328:Adult; D003746:Dental Enamel Proteins; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008875:Middle Aged; D010514:Periodontal Pocket / Q000601:surgery*; D013524:Surgical Flaps
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins