[Orthokeratinized odontogenic cyst: a clinicopathological and immunocytochemical study].
OBJECTIVE
To investigate the clinicopathological features and behavior of a group of jaw cysts with a solely orthokeratinized lining epithelium.


METHODS
20 cases of this cyst type were reported under the term of orthokeratinized odontogenic cyst (OOC) and their clinical, histological and immunocytochemical features were compared with that of odontogenic keratocyst (OKC).


RESULTS
The cysts of the present series were all solitary lesions, occurred mostly in young male patients, and showed a predilection for the posterior mandible areas. Follow-up of 15 patients revealed no recurrence following enucleation. Histological and immunocytochemical studies indicated that OOC epithelium lacked the typical features of OKC and appeared to show a lower proliferative activity.


CONCLUSIONS
These findings suggest that OOC is clinicopathologically distinctive from OKC and may thus constitute its own clinical entity.
Li
Tie-jun
TJ
Department of Pathology, Peking University School of Stomatology, Beijing 100081, China.
Luo
Hai-yan
HY
Yu
Shi-feng
SF
D000293:Adolescent; D000328:Adult; D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008336:Mandibular Diseases / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D018396:Mucin-1 / Q000032:analysis; D009807:Odontogenic Cysts / Q000378:metabolism / Q000473:pathology*
D002272:Carcinoembryonic Antigen; D018396:Mucin-1; D007633:Keratins