[Kinetic study on the volatility of menthol and borneol].
OBJECTIVE
To study the volatile regularity of menthol and borneol in granule and lozenge at different temperature.


METHODS
Kinetic method with GC being detection technique.


RESULTS
The volatility of menthol and borneol acts as a pseudo first-order reaction in open system. Under the same condition, the volatile rate of menthol and borneol in granule is four times as fast as that in lozenge, and the volatile rate of borneol is faster than that of menthol.


CONCLUSIONS
This study can be applied to improve the quality of lozenges containing menthol or/and borneol.
Zou
Jie-ming
JM
Guilin Sanjin Pharmaceutical Co. Ltd., Guilin 541004, Guangxi, China.
Wang
Li-sheng
LS
Wen
Hui
H
Wang
Shu-lin
SL
D001892:Camphanes / Q000008:administration & dosage / Q000737:chemistry*; D003505:Cyclodextrins; D004337:Drug Carriers; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry*; D008610:Menthol / Q000008:administration & dosage / Q000737:chemistry*; D013607:Tablets; D013696:Temperature; D014835:Volatilization; D047392:beta-Cyclodextrins
D001892:Camphanes; D003505:Cyclodextrins; D004337:Drug Carriers; D004365:Drugs, Chinese Herbal; D013607:Tablets; D047392:beta-Cyclodextrins; D008610:Menthol; C031215:betadex; C022871:isoborneol