Prevalence of antigliadin antibodies in ataxia patients.
We determined antigliadin antibodies in 95 ataxia patients and 73 controls. Antibodies were positive in 8% of the controls, 19% of patients with sporadic ataxia, 8% of patients with recessive ataxia, and 15% of patients with dominant ataxia. Statistical comparison using chi(2) statistics did not reveal significant differences between the groups. Although we found a trend toward a higher prevalence of antigliadin antibodies in patients with sporadic ataxia and dominant ataxia, our data do not support an association of ataxia with antigliadin antibodies.
Abele
M
M
Department of Neurology, University of Bonn, Germany.
Schöls
L
L
Schwartz
S
S
Klockgether
T
T
D000328:Adult; D000368:Aged; D000906:Antibodies / Q000097:blood / Q000276:immunology*; D000918:Antibody Specificity; D001259:Ataxia / Q000209:etiology / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity; D005903:Gliadin / Q000009:adverse effects / Q000276:immunology*; D005983:Glutens / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies
D000906:Antibodies; D005983:Glutens; D005903:Gliadin