Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies.
Shaw
Leslie M
LM
Department of Pathology & Laboratory Medicine, School of Pharmacy, University of Pittsburgh, PA 15261, USA. shawlmj@mail.med.upenn.edu
Korecka
Magdalena
M
Venkataramanan
Raman
R
Goldberg
Lee
L
Bloom
Roy
R
Brayman
Kenneth L
KL
D000328:Adult; D002384:Catalysis; D002648:Child; D016027:Heart Transplantation / Q000379:methods; D006801:Humans; D007168:IMP Dehydrogenase / Q000494:pharmacology; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics / Q000494:pharmacology; D016030:Kidney Transplantation / Q000379:methods; D008214:Lymphocytes / Q000187:drug effects; D008956:Models, Chemical; D009173:Mycophenolic Acid / Q000493:pharmacokinetics* / Q000494:pharmacology*; D012709:Serum Albumin / Q000378:metabolism; D013997:Time Factors; D014180:Transplantation / Q000379:methods*; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D012709:Serum Albumin; D007168:IMP Dehydrogenase; D009173:Mycophenolic Acid