An integral view of the neuroendocrine aspects of male sexual dysfunction and aging.
Age is the most important factor associated with sexual dysfunction. The traditional thinking explained this association by the neurovascular events developing with the aging process. More recently, central neuro-endocrine mechanisms resulting from apoptosis in the hypothalamic areas involved in both the production of sex hormones and the control of sexual processes have added a new dimension to human sexuality. This evidence is still controversial but of unquestionable importance in our understanding of endocrine alterations and sexual shortcomings associated with aging.
Morales
Alvaro
A
Department of Urology, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada.
D000375:Aging / Q000502:physiology*; D007172:Erectile Dysfunction / Q000503:physiopathology; D012739:Gonadal Steroid Hormones / Q000096:biosynthesis / Q000502:physiology; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D010410:Penile Erection / Q000502:physiology*; D012735:Sexual Dysfunction, Physiological / Q000503:physiopathology*
D012739:Gonadal Steroid Hormones