title: Evaluation of left ventricular volumes and ejection fraction using fast steady-state cine MR imaging: comparison with left ventricular angiography.
abstract: Previous studies demonstrated that magnetic resonance (MR) imaging consistently underestimated angiographic measurements of left ventricular (LV) volumes. The purpose of this study was to determine whether MR imaging with steady-state free precession acquisition (SSFP) can provide improved accuracy and reproducibility in measuring cardiac function in comparison with fast spoiled gradient echo cine MR imaging (SPGR). Twenty patients with cardiovascular diseases who underwent breath-hold cine MR imaging within one week of LV angiography were studied. Two sets of breath-hold cine MR images were obtained, one with SSFP and another with SPGR. The LV volumes determined by two breath-hold cine MR sequences were compared with the results by LV angiography. SPGR cine MR imaging consistently underestimated angiographic LV volumes. The mean difference of LV end-diastolic volume was -22.5 +/- 14.8 ml (p < 0.001) for short-axis planes and -27.7 +/- 21.5 ml (p < 0.001) for long-axis planes. In contrast, LV volumes measured by the SSFP imaging showed a good agreement with the results by angiography. The mean difference of LV end-diastolic volume was -2.5 +/- 14.3 ml (p = N.S.) for short-axis planes and -10.9 +/- 15.1 ml (p < 0.01) for long-axis planes. Standard error of the estimation in measuring LV end-diastolic volume with the SSFP imaging was 3.9% for short-axis images and 4.9% for long-axis images. These values were 7.2% and 8.7% with the SPGR imaging. In conclusion, the SSFP acquisition can provide accurate and noninvasive assessments of LV volumes and ejection fraction within a reduced imaging time.
authors.affiliation: Department of Radiology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie 514-8507, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Hajime
authors.initials: H
authors.lastname: Sakuma
authors.forename: Kakuya
authors.initials: K
authors.lastname: Kitagawa
authors.forename: Nanaka
authors.initials: N
authors.lastname: Ishida
authors.forename: Kan
authors.initials: K
authors.lastname: Takeda
authors.forename: Shoko
authors.initials: S
authors.lastname: Uemura
authors.forename: Munenobu
authors.initials: M
authors.lastname: Motoyasu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakano
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nozaki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D015588:Observer Variation; D015203:Reproducibility of Results; D013318:Stroke Volume / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology