Sesquiterpenes from roots of Lingularia veitchiana.
Together with seven known sesquiterpenes, a new guaiane, a new furanoeremophilane, and a new eudesmane were isolated from the roots of Ligularia veitchiana. Their structures were elucidated by spectroscopic methods. The bioactivities of three known guaiane sesquiterpenes were determined.
Wang
Ying
Y
Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, P.R. China.
Yuan
Cheng-Shan
CS
Han
Yi-Feng
YF
Jia
Zhong-Jian
ZJ
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000473:pathology; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D007202:Indicators and Reagents; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014750:Vincristine / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D007202:Indicators and Reagents; D012717:Sesquiterpenes; D014750:Vincristine