Burkitt-like lymphoma in an infant: a case report.
Childhood non-Hodgkin's lymphomas, including Burkitt and Burkitt-like, are rarely diagnosed in infants. A case of B-cell lymphoma in a 13-month-old girl with extensive abdominal disease, ascites, pleural effusion, and tumor lysis syndrome is reported. Phenotypic analysis showed a germinal center B-cell phenotype, and a B-cell clonality was confirmed by polymerase chain reaction. There was no evidence of Epstein-Barr and HIV infection. The case herein reported emphasizes the need for considering the diagnosis of lymphoma even in very young children.
Klumb
Claudete Esteves
CE
Cancer Hospital, National Institute of Cancer, Rio de Janeiro, Brazil.
de Resende
Lídia Maria Magalhães
LM
Stefanoff
Claudio Gustavo
CG
Vicuña
Carlos Humberto
CH
Renault
Ilana Zalcberg
IZ
Maia
Raquel Ciuvalschi
RC
D015703:Antigens, CD / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D002051:Burkitt Lymphoma / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D016483:Lymphoma, AIDS-Related / Q000276:immunology / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000473:pathology*; D010641:Phenotype; D016133:Polymerase Chain Reaction
D015703:Antigens, CD; D000951:Antigens, Neoplasm