Use of porcine small intestinal submucosa in Ehlers-Danlos syndrome Type IV.
Ehlers-Danlos syndrome (EDS) Type IV results in inadequate production of type III collagen and can lead to devastating vascular, gastrointestinal, and uterine complications. A case is presented of spontaneous colonic perforation in a patient with EDS Type IV complicated by multiple intestinal fistulas managed with porcine small intestinal submucosa. Early success with this technique would suggest additional applications in a variety of complicated gastrointestinal problems.
Wiedeman
James E
JE
Department of General Surgery, David Grant United States Air Force Medical Center, Travis Air Force Base, California, USA.
Ritter
Eric M
EM
D000328:Adult; D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D001672:Biocompatible Materials; D003082:Colectomy; D003108:Colonic Diseases / Q000209:etiology / Q000601:surgery*; D004535:Ehlers-Danlos Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology / Q000601:surgery*; D007413:Intestinal Mucosa; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery*; D007421:Intestine, Small / Q000601:surgery*; D013552:Swine
D001672:Biocompatible Materials