title: Resectable Pleomorphic Giant Cell Carcinoma of the Pancreas.
abstract: We present a 72-yr-old woman who underwent surgical resection of a large pancreatic tumor. On preoperativeimaging, an intratumoral cavity containing necrotic tissue was noted, mimicking the appearance of acystic tumor. There was no invasion of adjacent organs nor distant metastasis, and histopathologic examinationrevealed the tumor to be a giant cell carcinoma. Postoperatively, the patient has been followed for 1.5 yrwithout evidence of recurrence. Giant cell carcinoma generally is associated with a poor prognosis, and patientsusually die within months despite intensive multimodality therapy. Some patients with giant cell carcinomas,however, achieve long-term survival when invasion of adjacent organs and distant metastases are absent. Surgicalresection is the appropriate treatment for tumors with these favorable characteristics.
authors.affiliation: Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hirohashi
authors.forename: Hiromu
authors.initials: H
authors.lastname: Tanaka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Uenishi
authors.forename: Taichi
authors.initials: T
authors.lastname: Shuto
authors.forename: Shoji
authors.initials: S
authors.lastname: Kubo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kinoshita