Normal birth after microsurgical enucleation of tripronuclear human zygotes: case report.
Microsurgical enucleation of a single pronucleus from each of three tripronuclear zygotes was performed and the embryos were transferred to a 38-year-old woman on day 3 after fertilization. A normal healthy baby boy was born at 38 weeks and 4 days gestation, demonstrating that with polyspermic fertilization, removal of the extra male pronucleus allows the zygote to develop normally.
Kattera
Suresh
S
Centre for Reproductive Medicine and Gleneagles IVF Centre, Singapore 258500. kattera@singnet.com.sg
Chen
Christopher
C
D000328:Adult; D002467:Cell Nucleus; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D008866:Microsurgery; D018587:Oocyte Donation; D011247:Pregnancy; D011256:Pregnancy Outcome; D015053:Zygote / Q000648:ultrastructure*