[Treatment of cancer of the nasal cavity in 128 cases].
OBJECTIVE
To investigate the credibility of combined radiotherapy and surgery for cancer of the nasal cavity and their prognostic factors.


METHODS
One hundred and twenty-eight patients were treated from Mar. 1977 to Aug. 1993 receiving either radiotherapy alone (R group, 89), radiotherapy plus surgery (R + S group, 21), surgery plus radiotherapy (S + R group, 13), or surgery alone (S group, 5).


RESULTS
The overall 5-year survival rate was 42.2%. The 5-year survival rates of R, R + S and S + R groups were 33.7%, 57.1% and 61.5%, respectively. The 5-year survival rate of combined therapy for squamous cell carcinoma and low differentiated cancer were higher than that of radiotherapy alone, and the effect of radiotherapy alone for undifferentiated carcinoma was better. In early stage, the 5-year survival rate of the radiotherapy alone and combined therapy did not differ significantly. For III and IV stages, the 5-year survival rate of R + S combined therapy was higher than those with radiotherapy alone (P < 0.01).


CONCLUSIONS
For early lesions(Stage I and II), R alone or R + S give better results. For advanced lesions(Stage III and IV), combined radiotherapy and surgery is preferred. Radiotherapy alone is indicated for poorly differentiated cancers. Combined radiotherapy plus surgery is preferred for squamous cell carcinoma.
Wang
K
K
Department of Otorhinolaryngology, Zhejiang Cancer Hospital, Hangzhou 310022, China.
Shang
J
J
Xu
Y
Y
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate