title: Two genetic algorithms for identification of regulatory signals.
abstract: There exist numerous algorithms for identification of regulatory signals in unaligned DNA fragments. Here we present two genetic algorithms for signal identification and describe their implementation and testing on simulated and real data. The first algorithm selects the start position of the signal in a given fragment. The second one builds a "universal" word that is recognized by the transcription factor. We compare these approaches and study the behavior of the genetic algorithm.
authors.affiliation: Integrated Genomics, POBox 348, Moscow, 117333, Russia. esta 191@fromru.com
authors.forename: Elena D
authors.initials: ED
authors.lastname: Stavrovskaya
authors.forename: Andrey A
authors.initials: AA
authors.lastname: Mironov
mesh_terms: D000465:Algorithms; D016678:Genome; D008957:Models, Genetic; D012045:Regulatory Sequences, Nucleic Acid