title: [Diagnostic value of 99mTc-methoxy-isobutyl-isonitril and 99mTc-methylene diphosphonate scintimammography in the preoperative evaluation of breast cancer].
abstract: OBJECTIVE
  To compare and establish the value of 99mTc-MIBI (methoxyisobutiylisonitrile) and 99mTc-MDP (methylene diphosphonate) scintigraphy in patients with suspicion of breast cancer.
  
  
  METHODS
  The study included 105 patients. All patients were evaluated before surgery by 99mTc-MIBI and 99mTc-MDP scintigraphy. Thoracic SPECT study (Multispect II, Siemens) was performed 10 min. after i.v. injection of 99mTc-MIBI and 2 hours after i.v. injection of 99mTc-MDP. Final diagnosis was achieved after operation by histology.
  
  
  RESULTS
  99mTc-MIBI scintigraphy showed a better sensitivity (87%) than the 99mTc-MDP scintigraphy (81%) and the results are similar in specificity and validity, too.
  
  
  CONCLUSIONS
  The results suggest that 99mTc-MIBI scintigraphy is a useful method in the preoperative diagnosis of patients with suspicion of breast cancer.
authors.affiliation: Pécsi Tudományegyetem, Altalános Orvostudományi Kar, Központi Klinikai Radioizotóp Laboratórium. mibet@clinics.pote.hu
authors.forename: Erzsébet
authors.initials: E
authors.lastname: Schmidt
authors.forename: Károly
authors.initials: K
authors.lastname: Kett
authors.forename: Béla
authors.initials: B
authors.lastname: Anga
authors.forename: József
authors.initials: J
authors.lastname: Bódis
authors.forename: Katalin
authors.initials: K
authors.lastname: Zámbó
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D013669:Technetium Tc 99m Medronate; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013669:Technetium Tc 99m Medronate