Radial glia and somal translocation of radial neurons in the developing cerebral cortex.
A series of recent studies have demonstrated that radial glia are neural precursors in the developing cerebral cortex. These studies have further implied that these cells are the sole precursor constituents of the dorsal forebrain ventricular zone that generate the projection neurons of the cortex. In view of these new findings, this review discusses radial neurons, a progeny of cortical neurons that are generated by radial glia and adopt somal translocation as the mode of migration.
Nadarajah
Bagirathy
B
Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester, U.K.
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology* / Q000254:growth & development*; D006801:Humans; D009457:Neuroglia / Q000166:cytology* / Q000502:physiology; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology