Hodgkin Lymphoma in a patient with mycosis fungoides: molecular evidence for separate cellular origins.
We report the case of a man with mycosis fungoides (MF), who, 11 years after diagnosis, developed Hodgkin's disease. Although MF is associated with a higher than expected prevalence of other malignancies, including Hodgkin lymphoma, analysis of cells from the skin and lymph nodes showed findings that suggest a separate cellular origin for the two diseases.
Sidwell
R U
RU
Department of Dermatology, Royal Free Hospital, Pond Street, London NW3 2QG, UK.
McLaughlin
J E
JE
Jones
A
A
Whittaker
S J
SJ
D000328:Adult; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*