title: [Long-term health-related quality of life in chronic hepatitis B patients].
abstract: OBJECTIVE
  To evaluate their long-term outcome and the efficacy and economic significance of antiviral drugs by investigating the long-term health-related quality of life (HQL) in chronic hepatitis B (CHB) patients.
  
  
  METHODS
  The HQL of 101 CHB patients with biopsy-proven 6 to 18 years ago and 105 persons of general population as control was studied with revised SF-36 questionnaire.
  
  
  RESULTS
  The HQL in CHB patients was lower than that in general population in physical functioning, role physical, general health, mental health, and specific symptoms (mu > or = 2.10, P<0.05).
  
  
  CONCLUSIONS
  The long-term HQL in chronic hepatitis B patients is poor.
authors.affiliation: Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Chongqing 400010, China.
authors.forename: Gui-cheng
authors.initials: GC
authors.lastname: Wu
authors.forename: Wei-ping
authors.initials: WP
authors.lastname: Zhou
authors.forename: You-rong
authors.initials: YR
authors.lastname: Zhao
authors.forename: Shu-hua
authors.initials: SH
authors.lastname: Guo
authors.forename: Zhi-yi
authors.initials: ZY
authors.lastname: Wang
authors.forename: Shu-bi
authors.initials: SB
authors.lastname: Zou
authors.forename: Quan-hai
authors.initials: QH
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Ren
authors.forename: Ai-long
authors.initials: AL
authors.lastname: Huang
authors.forename: Ding-feng
authors.initials: DF
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D017281:Cost of Illness; D005260:Female; D005500:Follow-Up Studies; D019694:Hepatitis B, Chronic / Q000188:drug therapy / Q000191:economics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires
chemical_list: D000998:Antiviral Agents