Structure reassignment of the fungal metabolite TAEMC161 as the phytotoxin viridiol.
Two-dimensional NMR analyses including HMBC, NOESY, and ROESY as well as 1D NOE experiments led to a reassignment of the structure of the recently identified Trichoderma hamatum metabolite TAEMC161 (1) as the previously known viridiol (2). In addition, GIAO-calculated (13)C NMR chemical shifts of 1 and 2 provided strong support for the revised structure.
Wipf
Peter
P
Department of Chemistry, University of Pittsburgh, Pennsylvania 15260, USA.
Kerekes
Angela D
AD
D000734:Androstenediols / Q000737:chemistry*; D002247:Carbon Isotopes; D008968:Molecular Conformation; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D014242:Trichoderma / Q000737:chemistry*
D000734:Androstenediols; D002247:Carbon Isotopes; D009183:Mycotoxins; C055608:viridiol