title: Distribution of HLA-C alleles determined by PCR-SSP in the population of Lower Silesia.
abstract: We typed 100 unrelated, healthy Poles from the region of Lower Silesia for HLA-C using low-resolution polymerase chain reaction sequence-specific primers (PCR-SSP) and compared the observed allele frequencies with data published for other human populations. Poles appeared to be most similar to the Germans and English more distant from the French, Catalans and Basques and most dissimilar to non-Caucasians from Equatorial Guinea and Japan. It would be interesting to HLA-C-type other Slavic and non-Slavic peoples from Middle and Eastern Europe for comparison.
authors.affiliation: Laboratory of Immunogenetics, Department of Clinical Immunology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Prussak
authors.forename: Maria
authors.initials: M
authors.lastname: Mańczak
authors.forename: Bogusława
authors.initials: B
authors.lastname: Pochroń
authors.forename: Izabela
authors.initials: I
authors.lastname: Nowak
authors.forename: Piotr
authors.initials: P
authors.lastname: Kuśnierczyk
mesh_terms: D000483:Alleles; D017931:DNA Primers / Q000235:genetics; D005787:Gene Frequency; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D011044:Poland; D016133:Polymerase Chain Reaction
chemical_list: D017931:DNA Primers; D015236:HLA-C Antigens