Atomic force microscopy as a tool for biomedical and biotechnological studies.
This work presents different applications in progress with the aid of the atomic force microscopy (AFM) technique for biomedical and biotechnological applications, comprising both the acquisition of three-dimensional images and spectroscopic force measurements, in the following systems: first, low-density lipoprotein (LDL)-glycosaminoglycans; second, lectins-polysaccharides; third, mycobacterium leprae cellular wall and Vesicular Stomatites Virus (VSV) with fibronectin laminin, and lipidic membranes; fourth, DNA-complex; and fifth, actin, as well as the development of surface functionalizing protocols and image restoration by means of mathematical techniques.
Cidade
Geraldo Antônio Guerrera
GA
Instituto de Biofísica Carlos Chagas Filho, CCS, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Janeiro, RJ, Brazil. gcidade@biof.ufrj.br
Costa
Lilian Terezinha
LT
Weissmüller
Gilberto
G
da Silva Neto
Antônio José
AJ
Roberty
Nilson Costa
NC
de Moraes
Marta Bueno
MB
Prazeres
Gilza Maria Piedade
GM
Hill
Carlos Eduardo Marques
CE
Ribeiro
Simone Jesus Machado
SJ
de Souza
Gutierre Guarino Bastos
GG
da Silva Pinto Teixeira
Luciano
L
da Costa Monçores
Marlos
M
Bisch
Paulo Mascarello
PM
D020811:Biomedical Technology; D003585:Cell Biology / Q000295:instrumentation; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D021621:Imaging, Three-Dimensional; D018625:Microscopy, Atomic Force / Q000379:methods*; D013499:Surface Properties