[Stabilizing selection and computer models of the joint evolution of patterns of polygenes, transposable elements, and origin identity labels].
A computer model of the populations dynamics of the patterns of polygenes, transposable elements (TEs), and origin identity labels (OILs) in the course of stabilizing selection for an additive quantitative trait (with the target value being 0.4 of the maximum) was analyzed. It was demonstrated that the final plateaus of the trait value and the frequencies of the active values of polygenes are reached rapidly, namely, within five to seven generations (the effective selection period). The inbreeding coefficient during this period also grows rapidly and then gradually increases eventually reaching approximately 0.7. The inbreeding coefficient reaches plateau (at approximately 1.0) only in generations 300-350, which suggests the effect of gene drift. Dendrograms of the patterns of polygenes, TEs, and OILs were constructed for all generations. By generation 100 of selection, the final patterns of TEs and OILs were not formed completely. Fixations and losses, especially those of the OIL pattern, were delayed. In general, however, the population heterogeneity with respect to the patterns studied does not stabilize. This heterogeneity decreases the case of stabilizing selection, although more slowly than in the cases of positive and negative selections.
Ratner
V A
VA
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Department of Cytology and Genetics, Novosibirsk State University, Novosibirsk, 630090 Russia. ratner@bionet.nsc.ru
Egorova
A V
AV
Iudanin
A Ia
AIa
D000818:Animals; D005075:Biological Evolution; D003198:Computer Simulation; D004251:DNA Transposable Elements / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D040961:Genetic Drift; D018740:Genetic Heterogeneity; D005828:Genetics, Population; D007178:Inbreeding; D008297:Male; D011157:Population Dynamics; D019655:Quantitative Trait, Heritable; D012641:Selection, Genetic; D013997:Time Factors
D004251:DNA Transposable Elements