Motor proteins and kinesin-based nanoactuatoric devices.
Eukaryotic organisms synthesize diverse motor proteins converting chemical into mechanical energy. Among them, both rotary (e.g., ATP synthase) and linear motors are found. Linear motors comprise highly specialized proteins moving along nucleic acid filaments (in the case of e.g., RNA polymerase) or cytoskeletal filaments. The present paper provides a brief overview on cytoskeleton-associated motors (myosins, dyneins, and kinesins) and summarizes results contributing to elaborate a basic configuration for constructing a kinesin-driven motor device, suitable for e.g. a controlled displacement of objects or specific substances over millimetre distances with nanometre precision.
Böhm
K J
KJ
Institute of Molecular Biotechnology, Beutenbergstrasse 11, D-07745 Jena, Germany. kboehm@imb-jena.de
Stracke
R
R
Unger
E
E
D000255:Adenosine Triphosphate / Q000378:metabolism; D004398:Dyneins / Q000737:chemistry; D004734:Energy Metabolism; D016547:Kinesins / Q000737:chemistry*; D007700:Kinetics; D020409:Molecular Motor Proteins / Q000138:chemical synthesis / Q000737:chemistry*; D009218:Myosins / Q000737:chemistry; D036103:Nanotechnology
D020409:Molecular Motor Proteins; D000255:Adenosine Triphosphate; D009218:Myosins; D004398:Dyneins; D016547:Kinesins