title: Cortical ependymoma. A case report and review.
abstract: The authors report a rare case of a cortical ependymoma in a 10-year-old boy. The patient presented with complex partial seizures and a well-circumscribed, right frontal cortical mass. Routine microscopy showed a glial tumor with diverse histologic features. Immunohistochemistry and electron microscopy were required to establish the definitive diagnosis of cortical ependymoma. Cortical-based pediatric brain tumors range from World Health Organization grade I to III lesions and require significantly different treatment and follow-up. This case illustrates the importance of establishing an accurate neuropathologic tissue diagnosis of all pediatric cortical tumors.
authors.affiliation: Department of Pathology, Stanford University Medical Center, Calif 94305, USA. nlehman@stanford.edu
authors.forename: Norman L
authors.initials: NL
authors.lastname: Lehman
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Jorden
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Huhn
authors.forename: Patrick D
authors.initials: PD
authors.lastname: Barnes
authors.forename: Gregg B
authors.initials: GB
authors.lastname: Nelson
authors.forename: Paul G
authors.initials: PG
authors.lastname: Fisher
authors.forename: Dikran S
authors.initials: DS
authors.lastname: Horoupian
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D002540:Cerebral Cortex / Q000473:pathology* / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male