title: Granulomatous slack skin: treatment with extensive surgery and review of the literature.
abstract: We report an 11-year follow-up of a case of granulomatous slack skin. The patient was first treated surgically followed by a rapid relapse. Then he was treated by alpha-interferon during 15 months. When this treatment was stopped, the disease relapsed again. Extensive surgery was undertaken. Recently, a new relapse has occurred which was again treated by extensive surgery. No other manifestation of a lymphoproliferative disorder appeared. The clinical, histological, immunohistochemical, ultrastructural, molecular biological and genetic studies with a review of 39 other cases described in the literature are presented.
authors.affiliation: Department of Dermatology, Clinique Notre-Dame-de-Grâce, Charleroi, Belgium.
authors.forename: Magali
authors.initials: M
authors.lastname: Clarijs
authors.forename: Françoise
authors.initials: F
authors.lastname: Poot
authors.forename: Andoni
authors.initials: A
authors.lastname: Laka
authors.forename: Christian
authors.initials: C
authors.lastname: Pirard
authors.forename: André
authors.initials: A
authors.lastname: Bourlond
mesh_terms: D000328:Adult; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000601:surgery*; D008297:Male; D012008:Recurrence; D012878:Skin Neoplasms / Q000601:surgery*; D016896:Treatment Outcome