title: Potential pitfalls in the use of surrogate endpoints in colorectal adenoma chemoprevention.
authors.forename: Bernard
authors.initials: B
authors.lastname: Levin
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications / Q000188:drug therapy*; D016588:Anticarcinogenic Agents / Q000008:administration & dosage*; D000975:Antioxidants / Q000008:administration & dosage*; D001205:Ascorbic Acid / Q000008:administration & dosage; D015982:Bias; D018890:Chemoprevention / Q000379:methods; D015179:Colorectal Neoplasms / Q000235:genetics / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D016019:Survival Analysis; D016896:Treatment Outcome; D014810:Vitamin E / Q000008:administration & dosage; D019207:beta Carotene / Q000008:administration & dosage
chemical_list: D016588:Anticarcinogenic Agents; D000975:Antioxidants; D019207:beta Carotene; D014810:Vitamin E; D001205:Ascorbic Acid