CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism.
Gaedigk
Andrea
A
Division of Developmental Pharmacology and Medical Toxicology, The Children's Mercy Hospital and Clinics, Kansas City, MO 64108, USA. agaedigk@cmh.edu
Ryder
Darren L
DL
Bradford
L DiAnne
LD
Leeder
J Steven
JS
D044383:Black People / Q000235:genetics; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D010641:Phenotype; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic; D044465:White People / Q000235:genetics
D019389:Cytochrome P-450 CYP2D6