title: In vitro pharmacological properties of two novel non-imidazole H3 receptor (H3R) antagonists.
authors.affiliation: Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, AP9A, R4MN, 100 Abbott Park Road, Abbott Park, Illinois 60064-6123, USA. betty.yao@abbott.com
authors.forename: B B
authors.initials: BB
authors.lastname: Yao
authors.forename: D G
authors.initials: DG
authors.lastname: Witte
authors.forename: T R
authors.initials: TR
authors.lastname: Miller
authors.forename: K M
authors.initials: KM
authors.lastname: Krueger
authors.forename: T L
authors.initials: TL
authors.lastname: Carr
authors.forename: C H
authors.initials: CH
authors.lastname: Kang
authors.forename: R
authors.initials: R
authors.lastname: Faghih
authors.forename: Y L
authors.initials: YL
authors.lastname: Bennani
authors.forename: T A
authors.initials: TA
authors.lastname: Esbenshade
authors.forename: A A
authors.initials: AA
authors.lastname: Hancock
mesh_terms: D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D001667:Binding, Competitive / Q000187:drug effects; D005576:Colforsin / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism; D017442:Histamine Agonists / Q000378:metabolism; D006633:Histamine Antagonists / Q000494:pharmacology*; D006801:Humans; D008024:Ligands; D008761:Methylhistamines / Q000378:metabolism; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology; D010879:Piperazines / Q000494:pharmacology*; D018100:Receptors, Histamine H3 / Q000187:drug effects* / Q000378:metabolism
chemical_list: C475225:4-((3-(4-(2-aminopropanoyl)-1-piperazinyl)propoxy)phenyl)cyclopropylmethanone; D017442:Histamine Agonists; D006633:Histamine Antagonists; D008024:Ligands; D008761:Methylhistamines; C475226:N-(2-(4-(3-(4-(cyclopropylcarbonyl)phenoxy)propyl)-1-piperazinyl)-1-methyl-2-oxoethyl)-2-furamide; D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D018100:Receptors, Histamine H3; D005576:Colforsin; C069357:alpha-methylhistamine; D000242:Cyclic AMP; D015056:1-Methyl-3-isobutylxanthine