title: Improvement in cognitive function after radical excision of an anterior skull base meningioma--a report of 2 cases.
abstract: It has been well documented that memory difficulties in patients with anterior skull base meningioma may improve after tumour resection. However, there have been few reports on studies where precise testing of cognitive function has been conducted before and after surgery. Here we report 2 cases of anterior skull base meningioma where 2 tests of cognitive function, the Wechsler adult intelligence scale-revised (WAIS-R) and the Wechsler memory scale-revised (WMS-R), were performed by the patient before and after surgical treatment. After the operation there was a dramatic increase in the performance IQ as measured by the WAIS-R. In addition, the scores for both the "Attention/Concentration" and the "Delayed Recall" subsets of the WMS-R scale improved. There were differences between the 2 patients in the length of time required for functional recovery and this was thought to be due to the tumour size and the age of the patient. The use of these scales would enable physicians who are treating patients with anterior skull base meningioma to assess the recovery time that is likely to be needed before full return of cognitive function after surgery.
authors.affiliation: Department of Neurosurgery, Yamaguchi University School of Medicine, Yamaguchi, Japan.
authors.forename: Hisaharu
authors.initials: H
authors.lastname: Goto
authors.forename: Takahumi
authors.initials: T
authors.lastname: Nishizaki
authors.forename: Koji
authors.initials: K
authors.lastname: Kajiwara
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Ohmoto
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Akimura
authors.forename: Shoichi
authors.initials: S
authors.lastname: Kato
authors.forename: Hidekatsu
authors.initials: H
authors.lastname: Kiya
authors.forename: Michiyasu
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000209:etiology*; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology; D008579:Meningioma / Q000523:psychology* / Q000601:surgery*; D008875:Middle Aged; D020127:Recovery of Function / Q000502:physiology; D019292:Skull Base Neoplasms / Q000523:psychology* / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014888:Wechsler Scales