[The analgesic and antispasmodic effects of guang tong xiao aerosol of TCM].
OBJECTIVE
To observe the analgesic and antispasmodic effects of Guang Tong Xiao Aerosol (GTXA).


METHODS
Writhing test and tail-flick of physical stimulation were made to study the analgesic effect on mice and rats.


CONCLUSIONS
GTXA given by gastrogavage in dose of 18.75 g.kg-1 or 12.50 g.kg-1 could markedly raise the pain threshold after chemical stimulation in mice and physical stimulation in rats, and had antispasmodic effects.
Wu
Z Y
ZY
Department of Immunology, Guang An Men Hospital, China Academy of TCM, Beijing 100053, China.
Wu
G J
GJ
Zhao
B M
BM
Li
J X
JX
D000336:Aerosols; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D017288:Pain Threshold / Q000187:drug effects; D010276:Parasympatholytics / Q000494:pharmacology*; D011897:Random Allocation; D051381:Rats; D012007:Rectum / Q000187:drug effects
D000336:Aerosols; D018712:Analgesics, Non-Narcotic; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010276:Parasympatholytics