Rates and predictors for relapse in medication overuse headache: a 1-year prospective study.
The authors prospectively studied 98 patients with medication overuse headache. The 1-year relapse rate was 38% but was lower for patients with migraine compared with tension-type headache (22% vs 73%, p < or = 0.002) and combination of migraine and tension-type headache (22% vs 77%, p < or = 0.0001). The rate was also lower for patients overusing triptans than ergots (19% vs 20%, NS) and analgesics (19% vs 58%, p < or = 0.001). The long-term success of withdrawal depends on the type of primary headache and the type of overused medication.
Katsarava
Z
Z
Department of Neurology, University Hospital Essen, Germany.
Limmroth
V
V
Finke
M
M
Diener
H C
HC
Fritsche
G
G
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000009:adverse effects*; D004876:Ergot Alkaloids / Q000009:adverse effects*; D005260:Female; D005858:Germany / Q000453:epidemiology; D020773:Headache Disorders / Q000139:chemically induced / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy / Q000453:epidemiology; D011446:Prospective Studies; D012008:Recurrence; D012651:Self Medication; D017366:Serotonin Receptor Agonists / Q000009:adverse effects*; D011795:Surveys and Questionnaires; D018781:Tension-Type Headache / Q000188:drug therapy / Q000453:epidemiology
D000700:Analgesics; D004876:Ergot Alkaloids; D017366:Serotonin Receptor Agonists