title: [Long-term follow-up of patients with obstructive sleep apnea syndrome treated with uvulopalatopharyngoplasty].
abstract: OBJECTIVE
  To study the long-term outcome of uvulopalatopharyngoplasty (UPPP) in the treatment of obstructive sleep apnea syndrome (OSAS).
  
  
  METHODS
  Long-term follow-up for 32 cases of patients with OSAS was conducted in 3 years after UPPP. The respiratory disturbance index (RDI), body mass index (BMI), blood pressure (BP), fasting blood glucose (FBG), triglyceride, cholesterol were followed.
  
  
  RESULTS
  RDI was reduced markedly from 58.1 +/- 25.5 to 38.7 +/- 15.3 at 3 years after UPPP. The total effective rate was 87.5% after one month. 55.2% after 3 years. Their BMI, BP, FBG, triglyceride and cholesterol were also reduce significantly.
  
  
  CONCLUSIONS
  UPPP can improve the hypoxemia of patients with OSAS, reduced the BP, FBG, BMI, improve the lipid metabolism. Long-term outcomes of UPPP were possibly related to the preoperative BMI, RDI, the skeletal structure of the upper airway and postoperative BMI change. After UPPP, long-term follow-up is recommended because some initially successfully treated patients with OSAS will relapse in the later follow-up.
authors.affiliation: Department of Otorhinolaryngology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China. shewandong@yeah.net
authors.forename: W
authors.initials: W
authors.lastname: She
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Qian
authors.forename: M
authors.initials: M
authors.lastname: Hang
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose; D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000378:metabolism / Q000601:surgery*; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D014609:Uvula / Q000601:surgery*
chemical_list: D001786:Blood Glucose; D014280:Triglycerides