title: Stereoselective synthesis of tetrasubstituted 2,3-dihydrofurans by one-step cyclization of beta-ketosulfides of benzothiazole and aldehydes in ionic liquids.
abstract: A stereoselective synthesis of tetrasubstituted 2,3-dihydrofurans was carried out in n-butylpyridinium tetrafluoroborate ([bpy(+)][BF(4)(-)]) as solvent. The reaction proceeds smoothly in one step starting from simple materials such as aldehydes and beta-ketosulfides of benzothiazole. A comparison between several ionic liquids (ILs) is presented, and the role of the benzothiazolyl moiety is discussed. Workup proved to be very easy and recycling of IL possible.
authors.affiliation: Istituto di Chimica dei Composti Organometallici - ICCOM, Department of Chemistry, University of Bari, Via Amendola 173, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Calò
authors.forename: Fernando
authors.initials: F
authors.lastname: Scordari
authors.forename: Angelo
authors.initials: A
authors.lastname: Nacci
authors.forename: Emanuela
authors.initials: E
authors.lastname: Schingaro
authors.forename: Lucia
authors.initials: L
authors.lastname: D'Accolti
authors.forename: Antonio
authors.initials: A
authors.lastname: Monopoli