Calcific aortic stenosis: another face of atherosclerosis?
Calcific aortic stenosis is not the result of decades of wear and tear alone. Rather, it is being increasingly recognized as an inflammatory, atheromatous, and potentially modifiable disease. Exciting new research suggests that medical therapies may soon be available to retard its progression and reduce the need for surgery.
Novaro
Gian M
GM
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44122, USA.
Griffin
Brian P
BP
D001024:Aortic Valve Stenosis / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D002114:Calcinosis / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D018450:Disease Progression; D006710:Homocysteine / Q000097:blood; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy*; D012307:Risk Factors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D006710:Homocysteine