Spinal cord injury: inductive lability can enhance and hasten recovery.
In spinal cord injury, recovery of function, if any, confirms the presence of survived neural tissue at the injury site. However, recovery several years after the injury remains unexplained. Body weight bearing locomotor exercises seem to bring these new outcomes. Developing locomotor system and computer simulation studies show that motor learning requires the presence of redundant sets of competing synapses within the spinal cord interneurons. The new exercise regimens have not addressed this essential prerequisite; this could perhaps explain the long delays in recovery. We recommend that inclusion of inductive lability procedure (Krishnan, 1983, 1991, 2003) will help hasten and enhance the recovery.
Krishnan
R V
RV
Department of Anatomy, Dr. A.L. Mudaliar Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai, India. krish_venk@yahoo.com
D000818:Animals; D018678:Cholinergic Agents / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008954:Models, Biological; D009046:Motor Neurons / Q000502:physiology; D009473:Neuronal Plasticity / Q000187:drug effects / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology; D013119:Spinal Cord Injuries / Q000188:drug therapy / Q000503:physiopathology* / Q000534:rehabilitation*; D013997:Time Factors
D018678:Cholinergic Agents