title: Pseudomembranous and neutropenic enterocolitis in pediatric oncology patients.
abstract: Neutropenic enterocolitis in oncological patients represents a wide spectrum of clinicopathological pictures each with its own entity. Early diagnosis of enterocolitis can lead to improved supportive care and therefore better outcome. We present two cases--patient A, a child with pseudomembranous colitis caused by Clostridium difficile, and patient B, a child with neutropenic enterocolitis, where no organism was found. By allowing an insight into the pathology, immunology and culture results, we demonstrated that early diagnosis leads to improved management and therefore improved outcome.
authors.affiliation: Academic Medical Center, Emma Children's Hospital, Amsterdam, The Netherlands. m.d.vandewetering@amc.uva.nl
authors.forename: M D
authors.initials: MD
authors.lastname: van de Wetering
authors.forename: T W
authors.initials: TW
authors.lastname: Kuijpers
authors.forename: J A J M
authors.initials: JA
authors.lastname: Taminiau
authors.forename: F J W
authors.initials: FJ
authors.lastname: ten Kate
authors.forename: H N
authors.initials: HN
authors.lastname: Caron
mesh_terms: D000293:Adolescent; D002648:Child; D042241:Early Diagnosis; D044504:Enterocolitis, Neutropenic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D008297:Male; D010372:Pediatrics; D011379:Prognosis; D016896:Treatment Outcome