[Studies of bi-derectional modulation effect of kudzuvine root on immunol cells].
OBJECTIVE
To evaluate bi-directional modulation effect of Chinese herbal medicine on immunol cells.


METHODS
Two different active portions were isolated from Kudzuvine Root(Radix puerariae), one being the ethanol extraction and another the water extraction. Different concentration of these two different portions was studied by using PMA stimulated lymphocyte or eosinophil initiated chemiluminescence system.


RESULTS
Water extraction of Kudzuvine Root could enhance chemiluminescence concentration dependently whereas enthanol extraction of Kudzuvine Root inhibited the chemiluminescence significantly.


CONCLUSIONS
The bi-directional regulation effect of Chinese herbal medicine can be found in the same herb, because of its efficacy of different active compounds.
Song
Shu-zhen
SZ
Department of Clinical Biochemistry, Chinese PLA General Hospital, Beijing 100853, China.
Dong
Zhen-nan
ZN
Gu
Feng
F
Tian
Ya-ping
YP
D002469:Cell Separation; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects*; D000431:Ethanol; D006801:Humans; D008163:Luminescent Measurements; D008214:Lymphocytes / Q000187:drug effects*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D029908:Pueraria / Q000737:chemistry; D014867:Water
D004365:Drugs, Chinese Herbal; D014867:Water; D000431:Ethanol