The translation of capped mRNAs has an absolute requirement for the central domain of eIF4G but not for the cap-binding initiation factor eIF4E.
Ali
I K
IK
Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
Jackson
R J
RJ
D000818:Animals; D039561:Eukaryotic Initiation Factor-4E / Q000235:genetics*; D039603:Eukaryotic Initiation Factor-4G / Q000235:genetics*; D014176:Protein Biosynthesis; D012315:RNA Caps / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D012156:Reticulocytes / Q000378:metabolism; D013379:Substrate Specificity
D039561:Eukaryotic Initiation Factor-4E; D039603:Eukaryotic Initiation Factor-4G; D012315:RNA Caps; D012333:RNA, Messenger