Improved synthesis and in vitro evaluation of quinuclidin-2-ene based ligands for the nicotinic acetylcholine receptor.
Seifert
S
S
Institut für Pharmazeutische Chemie der Philipps-Universität Marburg, Germany.
Gündisch
D
D
Tilotta
M C
MC
Seitz
G
G
D018678:Cholinergic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D007202:Indicators and Reagents; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011812:Quinuclidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D011869:Radioligand Assay; D011978:Receptors, Nicotinic / Q000187:drug effects*; D013329:Structure-Activity Relationship
D018678:Cholinergic Agents; D007202:Indicators and Reagents; D008024:Ligands; D011812:Quinuclidines; D011978:Receptors, Nicotinic