title: Rapid recovery from acoustic trauma: chicken soup, potato knish, or drug interaction?
abstract: OBJECTIVE
  To describe the phenomenology and consider possible mechanisms mediating rapid and unexpected recovery from acoustic trauma after ingestion of a food substance (potato knish).
  
  
  METHODS
  Single subject with repeated test measures.
  
  
  METHODS
  Regional Veteran's Administration Medical Center, tertiary care medical center.
  
  
  METHODS
  Pure-tone audiometry and distortion product otoacoustic emissions (DPOAEs) performed at 6 days, 21 days, and 1 year postexposure.
  
  
  RESULTS
  Medical treatment with corticosteriods and a diuretic alone failed to improve auditory function and related symptoms (tinnitus and aural fullness) over a 2-week period. Rapid recovery of auditory function (dramatic improvement in pure tone thresholds; reappearance of DPOAEs) and abatement of related symptoms directly followed physiologic reactions from ingesting a food substance.
  
  
  CONCLUSIONS
  Rapid recovery from acoustic trauma was temporally correlated with urodynamic and cardiovascular reactions from ingesting food containing sulfite preservative, a substance to which the individual was allergic. Factors that may have contributed to recovery of function include massive diuresis, increased heart rate, release of biochemical mediators, mediator-induced vasodilatation, and changes in vascular or cell membrane permeability. Establishing relationships that lead to recovery of function from acoustic trauma may facilitate research and aid in the development of new treatment options for this condition.
authors.affiliation: Department of Surgery, Albany Medical College, Albany, NY 12208, USA.
authors.forename: Anthony T
authors.initials: AT
authors.lastname: Cacace
authors.forename: Steven M
authors.initials: SM
authors.lastname: Silver
authors.forename: Martha
authors.initials: M
authors.lastname: Farber
mesh_terms: D000707:Anaphylaxis; D001301:Audiometry, Pure-Tone; D004347:Drug Interactions; D005260:Female; D005502:Food; D005665:Furosemide / Q000627:therapeutic use; D006317:Hearing Loss, Noise-Induced / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous; D011241:Prednisone / Q000627:therapeutic use; D011198:Solanum tuberosum; D013447:Sulfites
chemical_list: D013447:Sulfites; D005665:Furosemide; D011241:Prednisone