title: Stereoselective synthesis of functionalized precursors of the CDEF and CDE 2,6-dideoxy-tetra- and trisaccharide units of durhamycins A and B.
abstract: [structure: see text] Highly stereoselective syntheses of functionalized precursors of the CDEF and CDE 2,6-dideoxy-tetra- and trisaccharide units of the anti-HIV aureolic acids durhamycins A and B using 2-deoxy-2-iodo- and 2-deoxy-2-bromopyranosyl donors are described.
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors.forename: Timothy B
authors.initials: TB
authors.lastname: Durham
authors.forename: William R
authors.initials: WR
authors.lastname: Roush
mesh_terms: D002240:Carbohydrate Sequence; D006027:Glycosides / Q000138:chemical synthesis; D006094:Gram-Positive Bacteria / Q000737:chemistry; D007202:Indicators and Reagents; D008969:Molecular Sequence Data; D008926:Plicamycin / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014312:Trisaccharides / Q000138:chemical synthesis*
chemical_list: D006027:Glycosides; D007202:Indicators and Reagents; D014312:Trisaccharides; C466115:durhamycin A; C466116:durhamycin B; D008926:Plicamycin