Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases.
Phytoestrogens constitute a promising alternative in the treatment of diseases associated with menopause. Nevertheless, the lack of data concerning their pharmacology and their toxicology requires use precautions. After reminding the pharmacology of estrogen receptors, this review outlines the estrogenicity and the therapeutic potentialities of phytoestrogens according to their structure.
Jacquot
Y
Y
Equipe de Chimie Thérapeutique, Faculté de Médecine et de Pharmacie, Place Saint-Jacques, 25030 Besançon, France.
Rojas
C
C
Refouvelet
B
B
Robert
J F
JF
Leclercq
G
G
Xicluna
A
A
D006801:Humans; D007529:Isoflavones / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use*; D048789:Phytoestrogens; D028321:Plant Preparations / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use*; D017698:Postmenopause / Q000187:drug effects / Q000502:physiology*; D011315:Preventive Medicine / Q000379:methods*
D007529:Isoflavones; D048789:Phytoestrogens; D028321:Plant Preparations