Palladium catalysed cyclisation-carbonylation of enynes to give cyclic gamma,delta-unsaturated acids.
In the presence of acetic acid, trifurylphosphine and CO (2 atm), palladium catalyses the conversion of a range of enynes to cyclic delta,gamma-unsaturated carboxylic acids in good yield.
Aggarwal
Varinder K
VK
School of Chemistry, Bristol University, Cantock's Close, Bristol, UK BS8 1TS. v.aggarwal@bristol.ac.uk
Butters
Mike
M
Davies
Paul W
PW