title: Validation of the Edinburgh Postnatal Depression Scale (EPDS) in Spanish mothers.
abstract: BACKGROUND
  The EPDS is a 10-items self-report scale designed as a specific instrument to detect postnatal depression. It was validated in the UK and in other countries, but not in Spain.
  
  
  METHODS
  We report data from all women (n=1201) attending in a routine postnatal check-up at 6 weeks postpartum during 1 year. A two-stage method was used: for the first stage, all individuals selected completed the EPDS; in the second one, 'probable cases' (n=261) with EPDS score >/=9, and a randomised sample of 10% with EPDS score less than 9 (n=126) were interviewed by a psychiatrist using the Structured Clinical Interview for DSM-IV, non-patient (SCID-NP), to establish psychiatric diagnosis of major and minor depression.
  
  
  RESULTS
  The best cut-off of the Spanish validation of the EPDS was 10/11 for combined major and minor depression, the sensitivity was 79%, and specificity was 95.5%, with a positive predictive value of 63.2% and a negative predictive value of 97.7%. At this cut-off all cases of major depression were detected. The area under the ROC curve was 0.976 (P<0.0001) with an asymptotic interval of confidence of 95% between 0.968 and 0.984.
  
  
  CONCLUSIONS
  Our data confirm the validity of the EPDS to identify postnatal depression in its Spanish version. The cut-off 10/11 for major and minor combined depression is useful to screen for a posterior psychiatric evaluation in Spanish sample.
authors.affiliation: Unit for Psychiatry and Psychology of Women, Hospital Casa de Maternitat, Institut Clínic de Psiquiatria i Psicologia, Sabino de Arana 1, 08028 Barcelona, Spain. lesteve@clinic.ub.es
authors.forename: Lluïsa
authors.initials: L
authors.lastname: Garcia-Esteve
authors.forename: Carlos
authors.initials: C
authors.lastname: Ascaso
authors.forename: Julia
authors.initials: J
authors.lastname: Ojuel
authors.forename: Puri
authors.initials: P
authors.lastname: Navarro
mesh_terms: D000328:Adult; D002391:Catchment Area, Health; D019052:Depression, Postpartum / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D009035:Mothers / Q000523:psychology*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires