title: Incidence of sympathetic ophthalmia after penetrating eye injury and choice of treatment.
abstract: BACKGROUND
  Sympathetic ophthalmia, a diffuse bilateral granulomatous panuveitis, is a serious potential complication after penetrating eye injury. Many surgeons recommend enucleation within two weeks of trauma to prevent this condition. We retrospectively reviewed the medical records of patients with penetrating ocular injuries who had either evisceration or enucleation to determine the incidence of sympathetic ophthalmia and to evaluate the surgical interventions and their complications. Age at surgery, time after penetrating trauma, surgery technique, follow-up period, ophthalmic examination of the fellow eye, and surgical complications were evaluated.
  
  
  RESULTS
  In total, 217 patients were included in the study with a mean follow-up period of 10.3 +/- 6.6 years. The longest time between the trauma and time of surgery was 43 years. Postoperative uveitis was observed in only one patient (0.5%) who had primary repair after injury. Histopathological review did not reveal typical sympathetic ophthalmia. Complications after enucleation were significantly higher than after evisceration.
  
  
  CONCLUSIONS
  There was no histopathologically supported sympathetic ophthalmia in our series. Sympathetic ophthalmia is very rare even when the injured eye is retained. With this in mind, the first choice of treatment may not be enucleation. Furthermore, evisceration may be the procedure of choice if primary repair cannot be performed or for patients who have panophthalmitis.
authors.affiliation: Ophthalmology Department, IstanbulPI Education and Research Hospital, Istanbul, Turkey. gurdalcm@yahoo.com
authors.forename: Canan
authors.initials: C
authors.lastname: Gürdal
authors.forename: Uğur
authors.initials: U
authors.lastname: Erdener
authors.forename: Murat
authors.initials: M
authors.lastname: Irkeç
authors.forename: Mehmet
authors.initials: M
authors.lastname: Orhan
mesh_terms: D015353:Eye Enucleation; D017234:Eye Evisceration; D015807:Eye Injuries, Penetrating / Q000150:complications* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009879:Ophthalmia, Sympathetic / Q000453:epidemiology* / Q000209:etiology*; D012189:Retrospective Studies; D013997:Time Factors; D014421:Turkey / Q000453:epidemiology