Cyclooxygenase-2: a target for the prevention and treatment of cancers of the upper digestive tract.
Altorki
Nasser K
NK
Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, Stang Cancer Prevention Center, New York, N.Y., USA. nkaltork@med.cornell.edu
Subbaramaiah
Kotha
K
Dannenberg
Andrew J
AJ
D000818:Animals; D017209:Apoptosis; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use*; D004067:Digestive System Neoplasms / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007108:Immune Tolerance; D007249:Inflammation / Q000150:complications; D007527:Isoenzymes / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000502:physiology; D008565:Membrane Proteins; D009389:Neovascularization, Pathologic / Q000209:etiology; D011451:Prostaglandin-Endoperoxide Synthases / Q000032:analysis / Q000502:physiology; D011453:Prostaglandins / Q000096:biosynthesis
D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D008565:Membrane Proteins; D011453:Prostaglandins; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases