title: Expedient acylations of primary and secondary alkyl cyanides to alpha-substituted beta-ketonitriles.
abstract: Primary and secondary cyanides are efficiently acylated with N-acylbenzotriazoles 3a-f (derived from a variety of acids) to afford the corresponding alpha-substituted beta-ketonitriles 5a-r in 67-96% yields.
authors.affiliation: Department of Chemistry, Center for Heterocyclic Compounds, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Ashraf A A
authors.initials: AA
authors.lastname: Abdel-Fattah
authors.forename: Mingyi
authors.initials: M
authors.lastname: Wang