[Effect of jiawei mojie tablet on plasma oxytocin level in patients with primary dysmenorrhea in menstrual period].
OBJECTIVE
To investigate the therapeutic mechanism of Jiawei Mojie Tablet (JMT) in treating primary dysmenorrhea (PD) by observing its effect on plasma oxytocin (OT) level in patients in menstrual period.


METHODS
Sixty-three patients with PD enrolled in the study were randomly divided into the JMT group (n = 33) and the control Group (n = 30, treated with Yueyueshu Granule) to observe the change of OT level in the menstrual period before and after treatment.


RESULTS
OT level in patients with PD was obviously higher than that in healthy subjects (P < 0.01), and was positively correlated with the degree of pain (r = 0.738, P < 0.01). OT level reduced significantly after treatment (P < 0.01), the reduction was more significant in the JMT group than that in the control group (P < 0.01).


CONCLUSIONS
JMT could reduce the OT level in menstrual period.
Deng
Hai-xia
HX
Department of Gynecology and Obstetrics, Affiliated Yueyang Hospital, Shanghai University of TCM, Shanghai 200437.
Zhu
Nan-sun
NS
Wang
Cai-wen
CW
D000293:Adolescent; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004412:Dysmenorrhea / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D010121:Oxytocin / Q000097:blood*; D013607:Tablets
D004365:Drugs, Chinese Herbal; D013607:Tablets; D010121:Oxytocin