title: [Kikuchi's histiocytic necrotizing lymphadenitis].
abstract: Necrotizing histiocytic lymphadenitis (NHL) or Kikuchi-Fujimoto disease is an infrequent seen clinicopathologic entity that affects most frequently young women and individuals of eastern races, and that is characterized by fever and adenopathies (basically cervical) and systemic disease even though occasional patients present extranodal disease. We present two young women with NHL and cutaneous affectation, and with lymphocytic meningitis in one of the patients. We discuss the etiology of NHL, the relation of NHL with collagen-vascular diseases (basically systemic erythematous lupus) the problem of the pathologic diagnosis, and the therapeutic possibilities in these patients.
authors.affiliation: Servicio de Medicina Interna. Hospital Severo Ochoa. Leganés. Madrid. Spain. aragonz@eresmas.com
authors.forename: G
authors.initials: G
authors.lastname: Eroles Vega
authors.forename: C
authors.initials: C
authors.lastname: Vicente Martín
authors.forename: J J
authors.initials: JJ
authors.lastname: Jusdado Ruiz-Capillas
authors.forename: M
authors.initials: M
authors.lastname: Guijarro Rojas
authors.forename: C
authors.initials: C
authors.lastname: Lacambra Calvet
authors.forename: F
authors.initials: F
authors.lastname: Burgos Lázaro
authors.forename: J
authors.initials: J
authors.lastname: Solís Villa
mesh_terms: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology*; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D009000:Monocytes / Q000473:pathology; D009333:Neck
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal