A new allelic variation within the 5'-flanking region of the interleukin-10 gene.
At -2471 bp from the transcriptional start site of the interleukin-10 (IL-10) gene, the inverted repeat TG/CA was previously identified and designated IL-10.IR. In an analysis of samples from 200 Germans (Caucasian) and 286 Gabonese (Central African), three different alleles, IL-10.IR6, IL-10.IR7 and IL-10.IR8, were identified. In the Caucasians, IL-10.IR6 and IL-10.IR8 were found only once, in each case with IL-10.IR7 as the corresponding second allele.
Rieth
H
H
Sektion Humanparasitologie des Instituts für Tropenmedizin, Eberhard-Karls-Universität, Tübingen, Germany. horst.rieth@web.de
Assohou
A C
AC
Mörmann
M
M
Roupelieva
M
M
Kremsner
P G
PG
Kube
D
D
D024506:5' Flanking Region; D000483:Alleles; D044383:Black People / Q000235:genetics; D016022:Case-Control Studies; D002648:Child; D005681:Gabon; D014644:Genetic Variation; D005858:Germany; D006801:Humans; D016753:Interleukin-10 / Q000235:genetics*; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000235:genetics; D008969:Molecular Sequence Data; D044465:White People / Q000235:genetics
D016753:Interleukin-10