Correlation between clinical classification, PEF and FEV1: guidelines and reality.
The currently proposed guidelines and consensus for asthma include Peak expiratory flow (PEF) and forced expiratory volume in the first second (FEV1) as two criteria to classify asthma severity. The report between these functional data and clinical classification degrees has been evaluated in 153 asthmatic patients. Concordance between functional evaluation and clinical degree has been found only for moderate persistent asthma but not for intermittent or mild persistent asthma. These results suggest that the correlation between clinical evaluation and lung function proposed in the guidelines must be reevaluated.
Palma-Carlos
A G
AG
Medical Clinic, Lisbon University Hospital and Center for Hematology and Imunology, CHIUL-Faculty of Medicine, Lisbon, Portugal.
Palma-Carlos
M L
ML
D000328:Adult; D001249:Asthma / Q000145:classification* / Q000503:physiopathology; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D010366:Peak Expiratory Flow Rate; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D012720:Severity of Illness Index