Herpetic whitlow during isotretinoin therapy.
Isotretinoin is an extremely valuable drug that is occasionally associated with well-known mucocutaneous side-effects, including cheilitis, retinoid dermatitis, palmoplantar desquamation, and photosensitivity. Paronychia has been reported rarely: only two prior cases of herpes simplex infections associated with isotretinoin have been previously reported. We present the first known case of herpetic paronychia occurring in an atopic patient while on isotretinoin therapy for acne.
Stetson
Cloyce L
CL
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. cloyce.stetson@ttuhsc.edu
Butler
David F
DF
Rapini
Ronald P
RP
D000152:Acne Vulgaris / Q000188:drug therapy; D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000009:adverse effects*; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects*; D008297:Male; D010304:Paronychia / Q000188:drug therapy / Q000821:virology*
D000998:Antiviral Agents; D003879:Dermatologic Agents; D015474:Isotretinoin; D000212:Acyclovir