title: Identification of organic eluates from four polymer-based dental filling materials.
abstract: Elution from polymer-based dental filling materials may have a potential impact on the biocompatibility of the materials. Since information from the manufacturers about ingredients in the materials often is incomplete, analyses of eluates from the materials are necessary for a better knowledge about possible harmful compounds. The aim of this study was to identify organic eluates from polymerized samples of two composites, one compomer and one resin-reinforced glass ionomer cement. Samples were immersed in ethanol or Ringer's solution. Organic leachables were analyzed by gas chromatography-mass spectrometry. Identification was confirmed with reference substances, if available. Among components detected were monomers, co-monomers, initiators, stabilizers, decomposition products and contaminants. Thirty-two substances were identified and 17 were confirmed with reference substances. From elution in Ringer's we identified 13 eluates from Tetric Ceram, 10 from Z250, 21 from Dyract and six from Fuji II LC; HEMA, HC and CQ were found in all samples. From elution in ethanol 12 eluates from Tetric Ceram, 18 eluates from Z250, 19 from Dyract and 10 from Fuji II LC were identified. The diversity of eluates from the four materials under study is demonstrated. Owing to variation between the materials, the biocompatibility including the allergenic potential may be different.
authors.affiliation: Department of Odontology-Cariology, University of Bergen, Armauer Hansens Hus, N-5021 Bergen, Norway. vibeke.michelsen@odont.uib.no
authors.forename: Vibeke Barman
authors.initials: VB
authors.lastname: Michelsen
authors.forename: Henning
authors.initials: H
authors.lastname: Lygre
authors.forename: Rita
authors.initials: R
authors.lastname: Skålevik
authors.forename: Anne Bjørg
authors.initials: AB
authors.lastname: Tveit
authors.forename: Einar
authors.initials: E
authors.lastname: Solheim
mesh_terms: D002849:Chromatography, Gas; D020770:Compomers / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods; D000431:Ethanol; D005899:Glass Ionomer Cements / Q000737:chemistry*; D007552:Isotonic Solutions; D013058:Mass Spectrometry; D008422:Materials Testing; D012117:Resins, Synthetic / Q000737:chemistry*; D000077331:Ringer's Solution
chemical_list: D020770:Compomers; D003188:Composite Resins; C088486:Dyract; C444701:Filtek Z250; C079765:Fuji II LC cement; D005899:Glass Ionomer Cements; D007552:Isotonic Solutions; D012117:Resins, Synthetic; C121818:Tetric ceram; D000431:Ethanol; D000077331:Ringer's Solution