title: Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations.
abstract: We describe a case of spontaneous twin ectopic pregnancy, managed with the combination of local injection under ultrasound control and intramuscular administration of methotrexate. We describe a difference between the area under the curve of declining plasma concentration of methotrexate after intramuscular and local injection.
authors.affiliation: Department of Gynecology and Obstetrics, Hôpital Antoine Beclere, Clamart, France.
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
authors.forename: P
authors.initials: P
authors.lastname: Bourget
authors.forename: C
authors.initials: C
authors.lastname: Lelaidier
authors.forename: S
authors.initials: S
authors.lastname: Doumerc
authors.forename: R
authors.initials: R
authors.lastname: Frydman