title: Structure and function of the thymus during adaptation of rats to hypergravitation.
abstract: Five-day exposure to hypergravitation (2g) induced structural and functional changes in the thymus: intensification of cell destruction and inhibition of mitotic activity of lymphocytes in all functional components of the organ. This leads to a significant (2-fold) decrease in thymus weight, area of the thymus cortex on histological section, blurring of the corticomedullary interface because of lymphocyte depletion of the cortical matter. The size and number of thymic bodies decrease 3.4 times compared to the control. This indicates that by day 5 of continuous hypergravitation (2g) exposure the lymphoid tissue does not completely adapt to hypergravitation.
authors.affiliation: Laboratory of Functional Anatomy, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow.
authors.forename: L M
authors.initials: LM
authors.lastname: Erofeeva
authors.forename: I B
authors.initials: IB
authors.lastname: Krasnov
authors.forename: M R
authors.initials: MR
authors.lastname: Sapin
mesh_terms: D000818:Animals; D018471:Hypergravity; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000166:cytology* / Q000378:metabolism*; D013997:Time Factors