title: Multistate outbreak of monkeypox--Illinois, Indiana, and Wisconsin, 2003.
abstract: CDC has received reports of patients with a febrile rash illness who had close contact with pet prairie dogs and other animals. The Marshfield Clinic, Marshfield, Wisconsin, identified a virus morphologically consistent with a poxvirus by electron microscopy of skin lesion tissue from a patient, lymph node tissue from the patient's pet prairie dog, and isolates of virus from culture of these tissues. Additional laboratory testing at CDC indicated that the causative agent is a monkeypox virus, a member of the orthopoxvirus group. This report summarizes initial descriptive epidemiologic, clinical, and laboratory data, interim infection-control guidance, and new animal import regulations.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000829:Animals, Domestic / Q000821:virology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D005869:Ghana; D006801:Humans; D007087:Illinois / Q000453:epidemiology; D007196:Indiana / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D008993:Monkeypox virus / Q000302:isolation & purification*; D011213:Poxviridae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission*; D012377:Rodentia / Q000821:virology*; D012589:Sciuridae / Q000821:virology*; D014922:Wisconsin / Q000453:epidemiology