title: Decompensated hepatitis B virus-related cirrhosis successfully treated with lamivudine allowing surgery for hepatocellular carcinoma.
abstract: A 39-year-old man was diagnosed with hepatitis B virus-related cirrhosis, and because of hepatic exacerbations with icterus and ascites, he had been repeatedly hospitalized. He was treated with lamivudine. Several months later, his ascites disappeared and his liver function was improved from class C to A according to the Child-Pugh classification. Two years later, one small hepatocellular carcinoma was detected, and he underwent a successful hepatectomy. From this case, we consider lamivudine to be useful for improving hepatic function in decompensated liver cirrhosis type B and lamivudine might enable surgical resection of hepatocellular carcinoma.
authors.affiliation: Third Department of Internal Medicine, Ehime University School of Medicine, Onsen-gun, Ehime.
authors.forename: Seiji
authors.initials: S
authors.lastname: Nakanishi
authors.forename: Kojiro
authors.initials: K
authors.lastname: Michitaka
authors.forename: Teruki
authors.initials: T
authors.lastname: Miyake
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hidaka
authors.forename: Itaru
authors.initials: I
authors.lastname: Yoshino
authors.forename: Ichiro
authors.initials: I
authors.lastname: Konishi
authors.forename: Hidehito
authors.initials: H
authors.lastname: Iuchi
authors.forename: Norio
authors.initials: N
authors.lastname: Horiike
authors.forename: Morikazu
authors.initials: M
authors.lastname: Onji
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006498:Hepatectomy; D006509:Hepatitis B / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use*; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D008297:Male; D011859:Radiography
chemical_list: D000998:Antiviral Agents; D019259:Lamivudine