Genetics of pediatric movement disorders.
Movement disorders in children often have a genetic basis. An explosion of genetic information in the past decade has led to the discovery of genetic defects in many forms of ataxia, parkinsonism, dystonia, tremor, and spastic paraparesis. This review focuses on genetically defined, early-onset diseases characterized primarily or exclusively by movement disorders. Particular emphasis is placed on disorders for which clinical or research testing is available.
Paulson
Henry L
HL
Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Paulson
George W
GW
D002648:Child; D006801:Humans; D009069:Movement Disorders / Q000235:genetics*; D010372:Pediatrics