Levels of coagulation factors and venous thromboembolism.
OBJECTIVE
Altered levels of coagulation factors have been included among the abnormalities that may increase the risk of venous thromboembolism (VTE) in otherwise healthy subjects.


METHODS
According to the studies that have been carried to test this hypothesis only elevated levels of factor VIII and fibrinogen emerged as independent risk factors for VTE.


CONCLUSIONS
Although some data indicate that elevated levels of factor XI or IX are also determinants for VTE, this awaits confirmation.
Tripodi
Armando
A
Angelo Bianchi Bonomi, Hemophilia and Thrombosis Center, Department of Internal Medicine, University and IRCCS Maggiore Hospital, Milan, Italy. armando.tripodi@unimi.it
D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000032:analysis*; D006801:Humans; D008954:Models, Biological; D012307:Risk Factors; D013923:Thromboembolism / Q000209:etiology*; D020246:Venous Thrombosis / Q000209:etiology*
D001779:Blood Coagulation Factors