title: Ceramic drug delivery: a perspective.
abstract: Different ceramic substances are offered in the market as bone substitute materials. These include monophasic calcium phosphate ceramics of tricalciumphosphate (TCP) or hydroxyapatite (HA), biphasic calcium phosphate ceramics and multiphasic bio-glasses synthetic calcium phosphate cements. Ceramics with appropriate three-dimensional geometry are able to bind and concentrate bone morphogenetic proteins in circulation and may become osteoinductive (capable of osteogenesis) and can be effective carriers of bioactive peptide or bone cell seeds and are therefore potentially useful in tissue engineering and drug delivery. An attempt has been made to review various drug delivery applications of ceramics.
authors.affiliation: Division of Biosurface Technology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695012, India.
authors.forename: Willi
authors.initials: W
authors.lastname: Paul
authors.forename: Chandra P
authors.initials: CP
authors.lastname: Sharma
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001843:Bone Cements / Q000737:chemistry; D019485:Bone Morphogenetic Proteins / Q000008:administration & dosage; D018786:Bone Substitutes / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry*; D016503:Drug Delivery Systems; D006801:Humans; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D019485:Bone Morphogenetic Proteins; D018786:Bone Substitutes