title: Evaluation of the time frame for home ipecac syrup use when not kept in the home.
abstract: BACKGROUND
  The home administration of ipecac syrup remains a recommendation in some guidelines for the management of specific pediatric poisonings. A common challenge for poison specialists is how to approach the situation when ipecac syrup is indicated but not kept in the home. This study examines whether or not ipecac syrup can be administered and produce timely emesis in this situation.
  
  
  METHODS
  Over a 6-month period, a prospective observational study was undertaken to determine if ipecac syrup can be administered in a timely manner when it is indicated but not available in the home. Cases where ipecac syrup was indicated but not kept in the home were included if parents stated that they could obtain ipecac within 15 minutes. Timely administration and the onset of emesis were defined as < 30 min and < 60 min, respectively.
  
  
  RESULTS
  During our study 14,603 human exposures were evaluated; ipecac syrup was recommended by a poison specialist in 75 cases, and 25 of these were included in our study. Ages ranged from 1 to 6 years. The mean time to administration of ipecac from exposure time was 40 min (SD +/- 14 min). Administration of ipecac syrup occurred in < 30 min in 20% of the cases. The mean time to first emesis from exposure was 58 min (SD +/- 13). Initial emesis occurred in < 60 min in 36% of the cases.
  
  
  CONCLUSIONS
  Ipecac syrup was rarely recommended by our center and was frequently unavailable when it was recommended. Ipecac syrup often could not be administered in a timely manner because it was not kept in the home. Parents of pediatric patients who have a significant ingestion should not be referred to purchase ipecac syrup.
authors.affiliation: North Texas Poison Center, University of Texas Southwestern School of Medicine, Dallas, Texas, USA.
authors.forename: James
authors.initials: J
authors.lastname: Garrison
authors.forename: Greene
authors.initials: G
authors.lastname: Shepherd
authors.forename: William L
authors.initials: WL
authors.lastname: Huddleston
authors.forename: William A
authors.initials: WA
authors.lastname: Watson
mesh_terms: D002648:Child; D002675:Child, Preschool; D004639:Emetics / Q000008:administration & dosage* / Q000600:supply & distribution; D006701:Home Nursing; D006801:Humans; D007223:Infant; D007486:Ipecac / Q000008:administration & dosage* / Q000600:supply & distribution; D010349:Patient Compliance; D011041:Poisoning / Q000188:drug therapy; D011446:Prospective Studies; D017216:Telemedicine; D013997:Time Factors
chemical_list: D004639:Emetics; D007486:Ipecac