Anatomical study of the pancreas in the house musk shrew (Suncus murinus), with special reference to the blood supply and innervation.
To examine the macroscopic structure, blood supply, and innervation of the pancreas in the house musk shrew (Suncus murinus), we performed gross anatomical dissection and whole-mount immunostaining of the autonomic nerve of Suncus pancreases based on neurofilament protein (NFP) immunoreactivity. The adult Suncus pancreas is clearly separated into right and left lobes that are not fused. The right lobe of the Suncus pancreas is located in the dorsum of the duodenum and to the right of the common bile duct independently. The right lobe is supplied by branches of the superior mesenteric artery, and is innervated by branches that originate from the superior mesenteric plexus and run along the arterial branches of the superior mesenteric artery. The left lobe occupies 9/10 of the entire pancreas and is located to the left of the common bile duct. It is supplied mainly by branches of the splenic and common hepatic arteries, and is innervated by branches that originate from the celiac plexus and run along the splenic and common hepatic arteries. According to previous studies on the blood supply and innervation of the human pancreas, the right and left lobes of the Suncus pancreas correspond to the pancreatic parts derived from the ventral and dorsal pancreatic buds. The current results suggest that the Suncus pancreas is a suitable experimental model for studying the development of the human pancreas.
Yi
Shuang-Qin
SQ
Department of Anatomy and Neuroembryology, Kanazawa University, Kanazawa, Japan. yixim@med.kanazawa-u.ac.jp
Shimokawa
Takashi
T
Akita
Keiichi
K
Ohta
Tetsuo
T
Kayahara
Masato
M
Miwa
Koichi
K
Tanaka
Shigenori
S
D000818:Animals; D001341:Autonomic Nervous System / Q000033:anatomy & histology; D002447:Celiac Plexus / Q000033:anatomy & histology; D005260:Female; D006499:Hepatic Artery / Q000033:anatomy & histology; D006801:Humans; D008297:Male; D008638:Mesenteric Arteries / Q000033:anatomy & histology; D010179:Pancreas / Q000098:blood supply* / Q000294:innervation*; D012788:Shrews / Q000033:anatomy & histology*; D013157:Splenic Artery / Q000033:anatomy & histology