Substituted hepta-1,6-dien-3-ones with green/fruity odours green/galbanum olfactophore model.
Following an analysis of available SAR data on green/galbanum-smelling molecules, a series of new 2-substituted hepta-1,6-dien-3-ones and their analogues were prepared and their olfactory properties evaluated. The study allowed to select efficient new odourants-potential substitutes for natural galbanum oil-and to generate an olfactophore model for the green/galbanum note.
Bajgrowicz
Jerzy A
JA
Givaudan Schweiz AG, Fragrance Research, Uberlandstrasse 138, CH-8600 Dübendorf, Switzerland. jerzy.bajgrowicz@givaudan.com
Berg-Schultz
Katja
K
Brunner
Gerhard
G
D005638:Fruit; D006536:Heptanes / Q000138:chemical synthesis / Q000494:pharmacology; D007659:Ketones / Q000138:chemical synthesis* / Q000494:pharmacology; D008958:Models, Molecular; D009812:Odorants; D010476:Perfume / Q000737:chemistry*; D021281:Quantitative Structure-Activity Relationship; D013329:Structure-Activity Relationship
D006536:Heptanes; D007659:Ketones; D010476:Perfume