Adenocarcinoma of the sigmoid colon seeding a chronic anal fistula: report of a case.
Damaged mucosal sites seem to be vulnerable to tumor cell implantation. We describe a case of exfoliated tumor cells from a sigmoid colon cancer seeding a long-standing anal fistula. The implications of this finding are reviewed.
Hyman
Neil
N
Department of Surgery, University of Vermont College of Medicine, Burlington, USA.
Kida
Masatoski
M
D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000378:metabolism; D053554:Keratin-20; D053552:Keratin-7; D007633:Keratins / Q000378:metabolism; D008297:Male; D009366:Neoplasm Seeding; D012811:Sigmoid Neoplasms / Q000378:metabolism / Q000473:pathology*
D007381:Intermediate Filament Proteins; C507499:KRT20 protein, human; C507497:KRT7 protein, human; D053554:Keratin-20; D053552:Keratin-7; D007633:Keratins