Bhc-diol as a photolabile protecting group for aldehydes and ketones.
[reaction: see text] 6-Bromo-4-(1,2-dihydroxyethyl)-7-hydroxycoumarin (Bhc-diol) can be used under simulated physiological conditions as a photoremovable protecting group for aldehydes and ketones. The single- and two-photon-induced release of benzaldehyde, piperonal, acetophenone, and cyclohexanone is demonstrated.
Lu
Min
M
Department of Chemistry, University of Georgia, Athens, Georgia 30602-2556, USA.
Fedoryak
Olesya D
OD
Moister
Brent R
BR
Dore
Timothy M
TM