Modeling of thermal skin injury for the development of local treatment drugs.
The paper describes simple and reliably reproducible methods of inducing superficial and deep skin burns (both infected and non-infected) in rats, which model IIIa and IIIb degree burns in humans. These methods reduce the costs and accelerate the development of local preparations.
Paramonov
V A
VA
St. Petersburg-Technology, St. Petersburg.
Chebotarev
V Yu
VY
D000818:Animals; D002056:Burns / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D003879:Dermatologic Agents / Q000627:therapeutic use; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D008297:Male; D051381:Rats; D015203:Reproducibility of Results
D003879:Dermatologic Agents