title: Addition of water to zinc triflate promotes a novel reaction: stereoselective Mannich-type reaction of chiral aldimines with 2-silyloxybutadienes.
abstract: A novel stereoselective Mannich-type reaction of chiral aldimines with 2-silyloxybutadienes in the presence of zinc triflate and water has been achieved. The diastereoselectivities of the products were 74-90% de, and no cycloadducts were detected. Classical Mannich-type products were also obtained by using zinc triflate and water with high diastereoselectivities.
authors.affiliation: Department of Chemistry, The National Defense Academy, 1-10-20 Hashirimizu, Yokosuka 239-8686, Japan. kaoriisi@nda.ac.jp
authors.forename: Kaori
authors.initials: K
authors.lastname: Ishimaru
authors.forename: Takakazu
authors.initials: T
authors.lastname: Kojima