Drosophila morphogenesis: the Newtonian revolution.
Recent quantitative modeling of dorsal closure in the fruitfly Drosophila has revealed how multiple forces drive sealing of the two symmetrical epithelial sheets. A predictive model based on the new data allows gene function to be linked to the forces that drive tissue movement.
Rousset
Raphaël
R
Institute of Signaling, Developmental Biology and Cancer, UMR 6543-CNRS, University of Nice Sophia-Antipolis, Parc Valrose, France.
Almeida
Luis
L
Noselli
Stéphane
S
D000818:Animals; D001696:Biomechanical Phenomena; D019521:Body Patterning / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D004330:Drosophila / Q000196:embryology*; D008954:Models, Biological; D009024:Morphogenesis