An unexpected highly stereoselective double aza-Baylis-Hillman reaction of sulfonated imines with phenyl vinyl ketone.
The aza-Baylis-Hillman reaction of N-sulfonated imine with phenyl vinyl ketone gave the double aza-Baylis-Hillman adduct in good yields with excellent stereoselectivities in the presence of Lewis base 1,4-diazabicyclo[2.2.2]octane.
Shi
Min
M
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 354 Fenglin Lu, Shanghai 200032, China. mshi@pub.sioc.ac.cn
Xu
Yong-Mei
YM