Hemodynamic performance of the Medtronic ADVANTAGE prosthetic heart valve in the aortic position: echocardiographic evaluation at one year.
OBJECTIVE
The study aim was to investigate the echocardiographic Doppler-derived hemodynamic results at one-year follow up at a single center for patients receiving the Medtronic ADVANTAGE aortic prosthetic heart valve. This study was part of a multi-center, prospective clinical evaluation of the ADVANTAGE bileaflet mechanical heart valve.


METHODS
Echocardiographic data were obtained one year postoperatively from 40 patients who underwent aortic valve replacement between November 1999 and March 2000. Data collected were in accordance with the Food and Drug Administration guidelines for clinical trials.


RESULTS
The in-vivo mean pressure gradients for valves implanted in the aortic position ranged from 11.2 mmHg for size 21 valves to 6.1 mmHg for size 29 valves, and the corresponding in-vivo effective orifice area ranged from 1.5 to 3.6 cm2.


CONCLUSIONS
Early results of the study showed hemodynamic performance of the ADVANTAGE aortic valve to be comparable with that of other bileaflet valves in current clinical use.
Koertke
Heinrich
H
Herzzentrum NRW, Bad Oeynhausen, Germany.
Seifert
Dirk
D
Drewek-Platena
Sylvia
S
Koerfer
Reiner
R
D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging* / Q000601:surgery*; D001705:Bioprosthesis; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011336:Probability; D011446:Prospective Studies; D011474:Prosthesis Design; D011475:Prosthesis Failure; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome