Emerging role of calprotectin in gastroenterology.
Calprotectin is a calcium and zinc binding protein of the S100 family derived predominantly from neutrophils and monocytes. It is detectable in body fluids and tissue samples and is emerging as a valuable marker in the diagnosis, and the monitoring and determining of the prognosis of commonly encountered gastroenterological conditions. Fecal calprotectin, in particular, has for a long time been regarded as a promising marker of gastrointestinal pathology and has now been established as a routine test in Norway and at several centers in the UK.
Poullis
Andrew
A
Gastroenterology, Endocrinology and Metabolism Division, St George's Hospital Medical School, London and Mayday University Hospital, Surrey, UK. apoullis@sghms.ac.uk
Foster
Russell
R
Mendall
Michael A
MA
Fagerhol
Magne K
MK
D015415:Biomarkers / Q000032:analysis*; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D006801:Humans; D039841:Leukocyte L1 Antigen Complex / Q000032:analysis*; D015032:Zinc / Q000494:pharmacology
D015415:Biomarkers; D039841:Leukocyte L1 Antigen Complex; D015032:Zinc