[Neurophysiological characteristics of infants and young children with auditory neuropathy].
OBJECTIVE
To analyze the neurophysiological characteristics of infants and young children with auditory neuropathy (AN) and explore their clinical significance.


METHODS
Audiological measurements (acoustic immittance, EOAEs, ABR, CM, MLR and ERP) and peripheral neurological tests were conducted and evaluated in 13 infants and young children with AN. 6 AN patients received CT scan and/or MRI examination.


RESULTS
All patients had type "A" tympanogram and normal CM. Normal EOAEs were elicited in 12 patients. 8 cases had normal MLR recording and 6 cases had normal ERP (P(300) and MMN). Peripheral neurological tests and CT and/or MRI showed normal results.


CONCLUSIONS
The diagnosis of AN in infants and young children should focus on analyzing their neurophysiological characteristics. Combined use of EOAEs, ABR and CM was recommended for hearing screening on newborns with high risk factors.
Wang
Deng-yuan
DY
Department of Otolaryngology, First affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Bu
Xing-kuan
XK
Xing
Guang-qian
GQ
Lu
Ling
L
D001304:Auditory Diseases, Central / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous; D011930:Reaction Time; D000160:Vestibulocochlear Nerve Diseases / Q000503:physiopathology*