title: Comparison of one-stage versus two-stage anteroposterior spinal fusion in pediatric patients with cerebral palsy and neuromuscular scoliosis.
abstract: METHODS
  A retrospective study was performed including 45 pediatric patients with spastic quadriplegic cerebral palsy and neuromuscular scoliosis who underwent anteroposterior spinal fusion.
  
  
  OBJECTIVE
  To evaluate the outcomes and complications of one-stage and two-stage combined anteroposterior spine fusion and to document which procedure is more efficacious and provides better results.
  
  
  BACKGROUND
  Circumferential spinal arthrodesis has been proven to achieve better scoliotic curve correction, decreasing significantly the risk of pseudarthrosis and progression of the deformity. There have been a few studies comparing same-day versus staged anteroposterior spinal surgery in mixed populations with neuromuscular scoliosis, but not in an isolated group of pediatric patients with spastic cerebral palsy.
  
  
  METHODS
  The medical records and radiographs of all patients were reviewed, and the results were statistically analyzed. The complications were divided into medical, subcategorized into major and minor, and technical.
  
  
  RESULTS
  There was no statistically significant difference (P > 0.05) between one-stage (Group 1) and two-stage (Group 2) patients, considering age at surgery, preoperative scoliosis angle, pelvic obliquity, kyphosis angle, lordosis angle, levels of anterior release, percentage of scoliosis correction, radiographic follow-up, hospitalization time, and intensive care unit stay. Sequentially performed spinal procedures (Group 1) were associated with increased intraoperative blood loss, prolonged operative time, and a considerably higher incidence of medical and technical complications, including two perioperative deaths.
  
  
  CONCLUSIONS
  Two-stage anteroposterior spinal fusion provides safer and more consistent results with several advantages over the single-stage procedure in the management of patients with cerebral palsy and neuromuscular scoliosis.
authors.affiliation: Alfred I. duPont Hospital for Children, Wilmington, Delaware 19899, USA.
authors.forename: Athanasios I
authors.initials: AI
authors.lastname: Tsirikos
authors.forename: Wei-Ning
authors.initials: WN
authors.lastname: Chang
authors.forename: K W
authors.initials: KW
authors.lastname: Dabney
authors.forename: Freeman
authors.initials: F
authors.lastname: Miller
mesh_terms: D000293:Adolescent; D000328:Adult; D002547:Cerebral Palsy / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D009468:Neuromuscular Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D009984:Orthopedic Fixation Devices; D011183:Postoperative Complications; D011782:Quadriplegia / Q000150:complications; D011859:Radiography; D012189:Retrospective Studies; D012600:Scoliosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D013123:Spinal Fusion / Q000379:methods*; D016896:Treatment Outcome