title: Fat-suppressed steady-state free precession imaging using phase detection.
abstract: Fully refocused steady-state free precession (SSFP) is a rapid, efficient imaging sequence that can provide diagnostically useful image contrast. In SSFP, the signal is refocused midway between excitation pulses, much like in a spin-echo experiment. However, in SSFP, the phase of the refocused spins alternates for each resonant frequency interval equal to the reciprocal of the sequence repetition time (TR). Appropriate selection of the TR results in a 180 degrees phase difference between lipid and water signals. This phase difference can be used for fat-water separation in SSFP without any increase in scan time. The technique is shown to produce excellent non-contrast-enhanced, flow-independent angiograms of the peripheral vasculature.
authors.affiliation: Department of Electrical Engineering, Stanford University, Stanford, California 94305-9510, USA. brian@mrsrl.stanford.edu
authors.forename: Brian A
authors.initials: BA
authors.lastname: Hargreaves
authors.forename: Shreyas S
authors.initials: SS
authors.lastname: Vasanawala
authors.forename: Krishna S
authors.initials: KS
authors.lastname: Nayak
authors.forename: Bob S
authors.initials: BS
authors.lastname: Hu
authors.forename: Dwight G
authors.initials: DG
authors.lastname: Nishimura
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008055:Lipids / Q000032:analysis / Q000737:chemistry*; D035002:Lower Extremity / Q000033:anatomy & histology* / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014867:Water / Q000032:analysis / Q000737:chemistry*
chemical_list: D008055:Lipids; D014867:Water