Transient lesion in the splenium of the corpus callosum in an epileptic patient.
Pathogenesis of a rarely occurring transient, isolated focal lesion of the splenium of the corpus callosum in epilepsy patients is uncertain: frequent seizures or antiepileptic drug reduction causing ischemia or demyelination is possible. The several MRI sequences, including diffusion-weighted imaging, in this first case of occipital epilepsy suggest ischemia from rapid carbamazepine reduction, frequent seizures, or a combination of both.
Mirsattari
Seyed M
SM
Department of Clinical Neurological Sciences, University of Western Ontario, Canada.
Lee
Donald H
DH
Jones
Michael W
MW
Blume
Warren T
WT
D000328:Adult; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging