[Diurnal blood pressure control in the optimal treatment of hypertension].
Mean 24-hour blood pressure values of ambulatory blood pressure monitoring (ABPM) are more closely related with target organ damage and cardiovascular events in hypertension, than clinic measurements. Both daytime and nighttime blood pressure and short-term blood pressure variability associated with these intermediate and hard cardiovascular outcomes abd should be controlled with antihypertensive treatment. A large increase in blood pressure variability may also occur in the early morning and with some antihypertensive drugs, without a consistent and smooth, more than 24-hour effect. For example, unlike some other angiotensin receptor blockers, telmisartan provides consistent blood pressure reduction for 24-hour, including the critical early morning period.
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Sándor
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Fóvárosi Szent Imre Kórház, I. Belosztály.
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D001562:Benzimidazoles / Q000494:pharmacology; D001565:Benzoates / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects*; D002940:Circadian Rhythm; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology*; D000077405:Irbesartan; D019808:Losartan / Q000494:pharmacology; D000077333:Telmisartan; D013777:Tetrazoles / Q000494:pharmacology; D014633:Valine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000068756:Valsartan
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D001562:Benzimidazoles; D001565:Benzoates; D001713:Biphenyl Compounds; D013777:Tetrazoles; D000068756:Valsartan; D014633:Valine; D000077405:Irbesartan; D019808:Losartan; C081643:candesartan; D000077333:Telmisartan