title: Evaluation of antimicrobial activities of Satureja hortensis L.
abstract: The present study was designated to evaluate the antimicrobial activities of methonol and hexane extracts of Satureja hortensis L. which is an annual herb used as traditional folk medicine in Eastern Anatolia region of Turkey for the treatment of different infectious diseases and disorders. The antimicrobial activities of the extracts against 147 laboratory strains belong to 55 bacterial species, and 31 isolates of 1 yeast and 4 fungi species were tested by using disc diffusion assay. The results showed that hexane extract of Satureja hortensis had no antifungal, but antibacterial activity against four strains of three Bacillus species whereas methanol extract of Satureja hortensis had both anticandidal and antibacterial effects. It inhibited the growth of 23 strains of 11 bacterial species and 6 isolates of Candida albicans, at the concentration of 300microg/ml. Satureja hortensis did not show antimicrobial activity against the remaining microorganisms (83%) tested including most and all of the clinic and plant pathogenic microorganisms, respectively. Methanol extract showed stronger and broader spectrum of antimicrobial activity as compared to hexane extract.
authors.affiliation: Department of Plant Protection, Faculty of Agriculture, Ataturk University, Erzurum 25240, Turkey. fsahin@atauni.edu.tr
authors.forename: F
authors.initials: F
authors.lastname: Sahin
authors.forename: I
authors.initials: I
authors.lastname: Karaman
authors.forename: M
authors.initials: M
authors.lastname: Güllüce
authors.forename: H
authors.initials: H
authors.lastname: Oğütçü
authors.forename: M
authors.initials: M
authors.lastname: Sengül
authors.forename: A
authors.initials: A
authors.lastname: Adigüzel
authors.forename: S
authors.initials: S
authors.lastname: Oztürk
authors.forename: R
authors.initials: R
authors.lastname: Kotan
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D035264:Flowers / Q000737:chemistry; D005658:Fungi / Q000187:drug effects; D006586:Hexanes; D000432:Methanol; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D031362:Satureja / Q000737:chemistry*; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D006586:Hexanes; D010936:Plant Extracts; D000432:Methanol