Novel rhodium-catalyzed cycloisomerization of 1,6-enynes with an intramolecular halogen shift.
A new Rh-catalyzed 1,6-enyne cycloisomerization process with a pi-allyl rhodium species as the key intermediate is investigated. A halogen shift happened in this novel process. The synthesis of stereodefined alpha-halomethylene gamma-butyrolactones has been achieved using the readily accessible Rh catalysts.
Tong
Xiaofeng
X
State Key Laboratory of Organometallics, Shanghai Institute of Organic Chemistry, Shanghai, 200032, P. R. China.
Zhang
Zhaoguo
Z
Zhang
Xumu
X