[The effect of the extract from Radix Paeoniae alba on IgA Glomerulonephritis in mice].
OBJECTIVE
To observe the effect of the extract from Radix Paeoniae Alba on IgA glomerulonephritis in mice.


METHODS
IgA glomerulonephritis was induced by injection of dextran and sephadex-150. After administrating the extract, the contents of urinary protein, BUN and Cr in serum were determined.


RESULTS
The extract could inhibit the decline of mouse weight, and decrease urinary protein content and BUN content in serum. While, the extract had no effect on Cr in serum.


CONCLUSIONS
The extract from Radix Paeoniae Alba had therapeutical effect on IgA glomerulonephritis.
Huang
Liming
L
No. 451 Hospital of PLA, Xi'an 710054.
Shi
Peng
P
Wang
Xixi
X
D000510:Alpha-Globulins / Q000378:metabolism*; D000818:Animals; D001806:Blood Urea Nitrogen; D001835:Body Weight / Q000187:drug effects; D003911:Dextrans; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005922:Glomerulonephritis, IGA / Q000139:chemically induced / Q000378:metabolism*; D008297:Male; D051379:Mice; D029596:Paeonia / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011506:Proteins
D000510:Alpha-Globulins; D003911:Dextrans; D004365:Drugs, Chinese Herbal; D011506:Proteins; C035737:major urinary proteins