Efficacy of a new intraaortic propeller pump vs the intraaortic balloon pump: an animal study.
OBJECTIVE
To compare the efficacy of a new intraaortic propeller pump (PP) to provide hemodynamic support to the intraaortic balloon pump (IABP) in an acute mitral regurgitation (MR) animal model.


BACKGROUND
A new intraaortic PP (Reitan catheter pump; Jomed; Helsingborg, Sweden) recently has been introduced. The pump's aim is a reduction in afterload via a deployable propeller that is placed in the high descending aorta and can be set at rotational speeds of <or= 14,000 revolutions per minute (rpm).


METHODS
In nine calves, acute MR was created by placing a vena cava filter in the mitral valve. The PP was tested at 6,000, 10,000, and 14,000 rpm and was compared to 1:1 IABP support. Cardiac output, coronary blood flow, carotid artery flow, ascending and abdominal aortic pressure, left atrial pressure, and LV pressure-volume loops were recorded.


RESULTS
The PP caused an rpm-dependent reduction in the mean ascending aortic pressure reaching -10 mm Hg (p < 0.05) at 14,000 rpm. However, mean (+/- SD) cardiac output did not improve (2.6 +/- 0.7 to 2.5 +/- 1.1 L/min; p = not significant), and mean diastolic coronary flow and carotid flow (47 +/- 16 to 35 +/- 15 centiliters/min, p < 0.05) were reduced. The IABP improved cardiac output, and carotid and diastolic coronary flow.


CONCLUSIONS
In this acute MR animal model, the PP reduced afterload but left out positive effects on cardiac output, which resulted in reduced perfusion of the upper body and the coronary circulation. Therefore, the IABP gives better hemodynamic support than the new PP in calves with acute MR.
Dekker
André
A
Department of Cardio Thoracic Surgery, Cardiovascular Research Institute Maastricht, Academic Hospital Maastricht, the Netherlands.
Reesink
Koen
K
van der Veen
Erik
E
Van Ommen
Vincent
V
Geskes
Gijs
G
Soemers
Cecile
C
Maessen
Jos
J
D000818:Animals; D001011:Aorta / Q000502:physiology; D001794:Blood Pressure; D002302:Cardiac Output; D002339:Carotid Arteries / Q000502:physiology; D002417:Cattle; D003326:Coronary Circulation; D004867:Equipment Design; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D008944:Mitral Valve Insufficiency / Q000628:therapy*; D016277:Ventricular Function, Left / Q000502:physiology