Small intestinal bacterial overgrowth: a possible risk factor for metabolic bone disease.
Small intestinal bacterial overgrowth (SIBO) is one of the causes of malabsorption syndromes. The prevalence of metabolic bone disease in patients with SIBO is unknown, but a recent prospective case-control study indicated significant contribution of SIBO to the development of metabolic bone disease. We review this and other reports in the literature and discuss the possible mechanisms causing metabolic bone disease in patients with SIBO.
Anantharaju
Abhinandana
A
Division of Gastroenterology, Hepatology and Nutrition, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA.
Klamut
Michael
M
D000328:Adult; D000368:Aged; D001851:Bone Diseases, Metabolic / Q000382:microbiology*; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000382:microbiology*; D008875:Middle Aged; D012307:Risk Factors