title: First-trimester diagnosis of nuchal anomalies: significance and fetal outcome.
abstract: High-resolution real-time ultrasonography now permits the differentiation between nuchal translucencies and cystic hygromata of the neck in the first trimester. A series of 85 nuchal anomalies are presented that were diagnosed by ultrasonography at 9-14 weeks' gestation; their association with chromosomal defects and fetal outcome are also presented. Chromosomal anomalies were found in 8/29 nuchal translucencies and in 16/56 cystic hygromata of the neck. However, in fetuses with normal karyotype, additional defects were diagnosed in l0/40 fetuses with cystic hygromata and in none with nuchal translucency. These data may be important for the management of these conditions and for counselling the patients toward further pregnancy.
authors.affiliation: Clinique Universitaire Port-Royal, Hopital Cochin, Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Ville
authors.forename: C
authors.initials: C
authors.lastname: Lalondrelle
authors.forename: S
authors.initials: S
authors.lastname: Doumerc
authors.forename: F
authors.initials: F
authors.lastname: Daffos
authors.forename: R
authors.initials: R
authors.lastname: Frydman
authors.forename: J F
authors.initials: JF
authors.lastname: Oury
authors.forename: Y
authors.initials: Y
authors.lastname: Dumez