First case of confirmed rotavirus meningoencephalitis in Germany.
We report the case of a 9-year-old girl in Germany with acute meningoencephalitis associated with rotavirus gastrointestinal infection. Sequence analysis revealed a genetic relationship of the strain to rotaviruses with subgroup II specificity. Reverse transcription-PCR was positive for rotavirus.
Kehle
Johannes
J
Laboratory Prof. G. Enders and Partner, Instituter for Virology, Infectology and Epidemiology e.V., Rosenbergstrasse 85, 70193 Stuttgart, Germany. kehle@virotest.com
Metzger-Boddien
Christoph
C
Tewald
Friedemann
F
Wald
Martin
M
Schüürmann
Joachim
J
Enders
Gisela
G
D000998:Antiviral Agents / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D007223:Infant; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000188:drug therapy; D012367:RNA, Viral / Q000032:analysis; D035583:Rare Diseases; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D012401:Rotavirus / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000175:diagnosis* / Q000188:drug therapy; D012720:Severity of Illness Index; D016896:Treatment Outcome
D000998:Antiviral Agents; D012367:RNA, Viral