title: HPLC analysis of metabolically produced formaldehyde.
abstract: Radiolabelled (-)-deprenyl is orally administered to rats, and urinary elimination of radiolabelled formaldehyde is detected. The separation is performed using high-performance liquid chromatography on octadecyl-silica stationary phase. Both the radioactivity and the UV absorbance of the dinitrophenylhydrazine formaldehyde peak are determined. Formaldehyde generation takes place by N-demethylation. Low levels of formaldehyde may have a beneficial role in counterbalancing the oxidative stress of the everyday person's life.
authors.affiliation: Semmelweis University, 1089 Budapest, Nagyvárad ter 4, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Lengyel
authors.forename: H
authors.initials: H
authors.lastname: Kalász
authors.forename: T
authors.initials: T
authors.lastname: Szarvas
authors.forename: Cs
authors.initials: C
authors.lastname: Peltz
authors.forename: A
authors.initials: A
authors.lastname: Szarkáné-Bolehovszky
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005557:Formaldehyde / Q000652:urine*; D008297:Male; D013058:Mass Spectrometry; D051381:Rats; D012015:Reference Standards
chemical_list: D005557:Formaldehyde