title: Inhalation aromatherapy during radiotherapy: results of a placebo-controlled double-blind randomized trial.
abstract: OBJECTIVE
  To determine whether the inhalation of aromatherapy during radiotherapy reduces anxiety.
  
  
  METHODS
  Three hundred thirteen patients undergoing radiotherapy were randomly assigned to receive either carrier oil with fractionated oils, carrier oil only, or pure essential oils of lavender, bergamot, and cedarwood administered by inhalation concurrently with radiation treatment. Patients underwent assessment by the Hospital Anxiety and Depression Scale (HADS) and the Somatic and Psychological Health Report (SPHERE) at baseline and at treatment completion.
  
  
  RESULTS
  There were no significant differences in HADS depression or SPHERE scores between the randomly assigned groups. However, HADS anxiety scores were significantly lower at treatment completion in the carrier oil only group compared with either of the fragrant arms (P =.04).
  
  
  CONCLUSIONS
  Aromatherapy, as administered in this study, is not beneficial.
authors.affiliation: Cancer Care Centre, St George Hospital, Gray St, Kogarah, Australia, 2217. grahamp@sesahs.nsw.gov.au
authors.forename: P H
authors.initials: PH
authors.lastname: Graham
authors.forename: L
authors.initials: L
authors.lastname: Browne
authors.forename: H
authors.initials: H
authors.lastname: Cox
authors.forename: J
authors.initials: J
authors.lastname: Graham
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control; D019341:Aromatherapy; D003863:Depression / Q000209:etiology / Q000517:prevention & control; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D027523:Lavandula; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology / Q000532:radiotherapy*; D009822:Oils, Volatile / Q000627:therapeutic use*; D010919:Placebos; D010938:Plant Oils; D011878:Radiotherapy / Q000523:psychology*; D016896:Treatment Outcome
chemical_list: D009822:Oils, Volatile; D010919:Placebos; D010938:Plant Oils; C068336:bergamot oil; C042023:cedarwood oil; C045718:lavender oil