title: Noninvasive imaging of protein-protein interactions in living organisms.
abstract: Genomic research is expected to generate new types of complex observational data, changing the types of experiments as well as our understanding of biological processes. The investigation and definition of relationships among proteins is essential for understanding the function of each gene and the mechanisms of biological processes that specific genes are involved in. Recently, a study by Paulmurugan et al. demonstrated a tool for in vivo noninvasive imaging of protein-protein interactions and intracellular networks.
authors.affiliation: Department of Nuclear Medicine, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg 69120, Germany. Uwe_Haberkorn@med.uni-heidelberg.de
authors.forename: Uwe
authors.initials: U
authors.lastname: Haberkorn
authors.forename: Annette
authors.initials: A
authors.lastname: Altmann
mesh_terms: D000818:Animals; D002477:Cells / Q000166:cytology / Q000000981:diagnostic imaging* / Q000378:metabolism*; D004734:Energy Metabolism / Q000502:physiology*; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods* / Q000639:trends; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D040901:Proteomics / Q000379:methods; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D014055:Tomography, Emission-Computed / Q000379:methods* / Q000639:trends; D020798:Two-Hybrid System Techniques
chemical_list: D011506:Proteins; D011993:Recombinant Fusion Proteins