title: Treatment of choroidal melanoma using photodynamic therapy.
abstract: OBJECTIVE
  To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma.
  
  
  METHODS
  Interventional case series.
  
  
  METHODS
  Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.
  
  
  RESULTS
  One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.
  
  
  CONCLUSIONS
  Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma.
authors.affiliation: E.S. Harkness Eye Institute, New York Presbyterian Hospital, Columbia University, New York, New York 10032, USA. ib206@columbia.edu
authors.forename: Irene A
authors.initials: IA
authors.lastname: Barbazetto
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Lee
authors.forename: Indira S
authors.initials: IS
authors.lastname: Rollins
authors.forename: Stanley
authors.initials: S
authors.lastname: Chang
authors.forename: David H
authors.initials: DH
authors.lastname: Abramson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002830:Choroid Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D008545:Melanoma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D014463:Ultrasonography; D000077362:Verteporfin
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin