title: First case of confirmed rotavirus meningoencephalitis in Germany.
abstract: We report the case of a 9-year-old girl in Germany with acute meningoencephalitis associated with rotavirus gastrointestinal infection. Sequence analysis revealed a genetic relationship of the strain to rotaviruses with subgroup II specificity. Reverse transcription-PCR was positive for rotavirus.
authors.affiliation: Laboratory Prof. G. Enders and Partner, Instituter for Virology, Infectology and Epidemiology e.V., Rosenbergstrasse 85, 70193 Stuttgart, Germany. kehle@virotest.com
authors.forename: Johannes
authors.initials: J
authors.lastname: Kehle
authors.forename: Christoph
authors.initials: C
authors.lastname: Metzger-Boddien
authors.forename: Friedemann
authors.initials: F
authors.lastname: Tewald
authors.forename: Martin
authors.initials: M
authors.lastname: Wald
authors.forename: Joachim
authors.initials: J
authors.lastname: Schüürmann
authors.forename: Gisela
authors.initials: G
authors.lastname: Enders
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D007223:Infant; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000188:drug therapy; D012367:RNA, Viral / Q000032:analysis; D035583:Rare Diseases; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018570:Risk Assessment; D012401:Rotavirus / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000175:diagnosis* / Q000188:drug therapy; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D012367:RNA, Viral