Structural and functional characteristics of lymphocytes in chronic carriers of tick-borne encephalitis virus.
Study of the surface phenotype, structure of plasma membrane, and activity of DNA repair system in peripheral blood lymphocytes from patients with different clinical forms of tick-borne encephalitis associated with long persistence of the virus revealed a pronounced imbalance between lymphocyte subpopulations, increased microviscosity of the plasma membrane lipid phase, and decreased activity of the DNA repair system in lymphocytes.
Ryazantseva
N V
NV
Siberian State Medical University. ryazan@mail.tomsknet.ru
Zhukova
O B
OB
Novitskii
V V
VV
Pirogova
N P
NP
Lepekhin
A V
AV
Tokareva
N V
NV
Mikhailova
O V
OV
Plotnikova
N N
NN
Sevost'yanova
N V
NV
D000328:Adult; D002353:Carrier State / Q000276:immunology; D002908:Chronic Disease; D004260:DNA Repair; D004675:Encephalitis, Tick-Borne / Q000097:blood / Q000276:immunology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D016131:Lymphocyte Subsets / Q000276:immunology / Q000473:pathology / Q000502:physiology; D008214:Lymphocytes / Q000276:immunology* / Q000473:pathology / Q000502:physiology; D008297:Male; D008560:Membrane Fluidity; D008563:Membrane Lipids / Q000097:blood; D008875:Middle Aged
D008563:Membrane Lipids