title: Diterpenoid and phenolic glycosides from the roots of Rhododendron molle.
abstract: Two new grayanane diterpenoid glucosides, rhodomosides A (1), B (2) and two new phenolic glycosides 3, 4 together with a known glucosyringic acid (5) were isolated from the roots of Rhododendron molle G. Don (Ericaceae). Their structures were elucidated on the basis of spectral analysis. Compounds 3, 4 and 5 were found to inhibit the proliferation of murine B lymphocytes in vitro, while compound 3 also showed stimulatory activity on the proliferation of murine T lymphocytes in vitro.
authors.affiliation: Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China.
authors.forename: Guan-Hu
authors.initials: GH
authors.lastname: Bao
authors.forename: Li-Quan
authors.initials: LQ
authors.lastname: Wang
authors.forename: Kin-Fai
authors.initials: KF
authors.lastname: Cheng
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Feng
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Li
authors.forename: Guo-Wei
authors.initials: GW
authors.lastname: Qin
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects*; D016572:Cyclosporine / Q000494:pharmacology; D004224:Diterpenes / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots; D029793:Rhododendron; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000187:drug effects*
chemical_list: D004224:Diterpenes; D006027:Glycosides; D007166:Immunosuppressive Agents; D010936:Plant Extracts; D016572:Cyclosporine