title: Acute vasculitis with multiorgan involvement in a patient with familial Mediterranean fever.
abstract: We report a rare case of a patient with long-standing familial Mediterranean fever who presented with sudden onset of dyspnea, abdominal pain, and cutaneous manifestations. Chest CT and histologic preparations disclosed pulmonary hemorrhage and signs of systemic vasculitis. Cyclophosphamide and steroid therapy were initiated, with marked improvement. Based on this and 1 other case, we propose that systemic vasculitis should be included as a clinical manifestation of FMF.
authors.affiliation: Department of Internal Medicine, Rambam Medical Center and B. Rappaport Faculty of Medicine, Technion, Haifa, Israel.
authors.forename: Eyal
authors.initials: E
authors.lastname: Braun
authors.forename: Daniel
authors.initials: D
authors.lastname: Schapira
authors.forename: Ludmila
authors.initials: L
authors.lastname: Guralnik
authors.forename: Zaher S
authors.initials: ZS
authors.lastname: Azzam
mesh_terms: D000208:Acute Disease; D000328:Adult; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009102:Multiple Organ Failure / Q000150:complications / Q000175:diagnosis*; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis*