Preparation of unidirectional end-grafted alpha-helical polypeptides by solvent quenching.
A simple "solvent quenching" approach to align an alpha-helical end-grafted poly(gamma-benzyl l-glutamate) monolayer is presented. By sequentially treating poly(gamma-benzyl l-glutamate) with good solvent (chloroform) and bad solvent (acetone), we obtained a highly aligned monolayer with an average tilt angle as small as 3 degrees .
Wang
Yuli
Y
Department of Chemical Engineering and Materials Science, University of California, Irvine, California 92697-2575, USA.
Chang
Ying Chih
YC
D000096:Acetone / Q000737:chemistry; D002725:Chloroform / Q000737:chemistry; D018625:Microscopy, Atomic Force; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*; D017433:Protein Structure, Secondary; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
D012997:Solvents; D000096:Acetone; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; D002725:Chloroform