title: Successful treatment of anabolic steroid-induced azoospermia with human chorionic gonadotropin and human menopausal gonadotropin.
abstract: OBJECTIVE
  To document for the first time the successful treatment using human chorionic gonadotropin (hCG) and human menopausal gonadotropins (hMG) of anabolic steroid-induced azoospermia that was persistent despite 1 year of cessation from steroid use.
  
  
  METHODS
  Clinical case report.
  
  
  METHODS
  Tertiary referral center for infertility.
  
  
  METHODS
  A married couple with primary subfertility secondary to azoospermia and male hypogonadotropic hypogonadism. The husband was a bodybuilder who admitted to have used the anabolic steroids testosterone cypionate, methandrostenolone, oxandrolone, testosterone propionate, oxymetholone, nandrolone decanoate, and methenolone enanthate.
  
  
  METHODS
  Twice-weekly injections of 10,000 IU of hCG (Profasi; Serono) and daily injections of 75 IU of hMG (Humegon; Organon) for 3 months.
  
  
  METHODS
  Semen analyses, pregnancy.
  
  
  RESULTS
  Semen analyses returned to normal after 3 months of treatment. The couple conceived spontaneously 7 months later.
  
  
  CONCLUSIONS
  Steroid-induced azoospermia that is persistent after cessation of steroid use can be treated successfully with hCG and hMG.
authors.affiliation: Department of Obstetrics and Gynecology, University Malaya Medical Centre, Kuala Lumpur, Malaysia. drmenon2000@yahoo.co.uk
authors.forename: Dev Kumar
authors.initials: DK
authors.lastname: Menon
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000009:adverse effects*; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008596:Menotropins / Q000627:therapeutic use*; D009845:Oligospermia / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D045930:Anabolic Agents; D006063:Chorionic Gonadotropin; D008596:Menotropins