[Anticitrulline antibodies - new marker in rheumatoid arthritis diagnostics].
The overview provides the knowledge about rheumatoid factor isotypes and their significance in the case of rheumatoid arthritis. New immunological methods have been introduced in the last decade proving their validity in seronegative rheumatoid arthritis. Antikeratin and anticitrulline antibodies were found to be useful diagnostic tools for seronegative and early rheumatoid arthritis. The methods perform well for scientific needs as well as in daily clinical practice.
Kirdaite
Gailute
G
Insitute of Experimental and Clinical Medicine, Vilnius University, Lithuania. gailak34@yahoo.fr
Redaitiene
Elvyra
E
Dadoniene
Jolanta
J
Stropuviene
Sigita
S
D000918:Antibody Specificity; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis*; D015415:Biomarkers; D002956:Citrulline / Q000276:immunology*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007633:Keratins / Q000276:immunology; D011379:Prognosis; D012217:Rheumatoid Factor / Q000032:analysis; D013997:Time Factors
D001323:Autoantibodies; D015415:Biomarkers; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D002956:Citrulline; D007633:Keratins; D012217:Rheumatoid Factor