title: Recall of severe hypoglycaemia and self-estimated state of awareness in type 1 diabetes.
abstract: BACKGROUND
  The ability of people with insulin-treated diabetes to remember severe hypoglycaemia and the consistency of their self-estimated awareness of hypoglycaemia are not well documented but are important in clinical practice. The aim of this study is to assess recall of severe hypoglycaemia in patients with type 1 diabetes and to evaluate the feasibility of a simple method for clinical classification of the awareness of hypoglycaemia.
  
  
  METHODS
  A one-year prospective study was performed on a cohort of patients with type 1 diabetes (n = 230). The rate of severe hypoglycaemia reported retrospectively at the end of the study was compared to the prospectively recorded rate during the study period. Self-estimated awareness was explored in questionnaires at baseline and at the end, and assessments were evaluated by the occurrence of severe hypoglycaemic episodes.
  
  
  RESULTS
  Almost 90% of the participants correctly recalled whether they had had severe hypoglycaemia. However, those with high prospectively recorded numbers had incomplete recall, resulting in a 15% underestimation of the overall rate. On the basis of the answer to the question "Do you recognise symptoms when you have a hypo?", the population was classified into three groups: 40% with normal awareness, 47% with impaired awareness and 13% with unawareness. The groups with impaired awareness and unawareness had 5.1 and 9.6 times higher rates of severe hypoglycaemia, respectively, compared to the group with normal awareness (p < 0.001).
  
  
  CONCLUSIONS
  People with type 1 diabetes generally remember severe hypoglycaemic episodes during a one-year period. A simple method is proposed for classifying the state of awareness of hypoglycaemia in clinical practice.
authors.affiliation: Department of Internal Medicine F, Hillerød Hospital, Helsevej 2, DK-3400 Hillerød, Denmark. ulpebj@fa.dk
authors.forename: Ulrik
authors.initials: U
authors.lastname: Pedersen-Bjergaard
authors.forename: Stig
authors.initials: S
authors.lastname: Pramming
authors.forename: Birger
authors.initials: B
authors.lastname: Thorsteinsson
mesh_terms: D017668:Age of Onset; D001364:Awareness; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology*; D008297:Male; D008568:Memory; D008875:Middle Aged; D010045:Outpatients; D011446:Prospective Studies; D011996:Records; D012044:Regression Analysis; D011795:Surveys and Questionnaires