title: Molecular and conventional epidemiology of tuberculosis in Hong Kong: a population-based prospective study.
abstract: A prospective population-based molecular and conventional epidemiological study of 65.4% of bacteriologically confirmed cases of tuberculosis was carried out on the island of Hong Kong from May 1999 to Oct 2000 by the IS6110-based restriction fragment length polymorphism technique. Eleven of the isolates had five or fewer bands; 24.5% of the remaining 691 isolates belonged to clusters. The estimated proportion of recently transmitted disease was 15 to 20%.
authors.affiliation: Hong Kong Government Tuberculosis and Chest Service, Department of Health, The University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China.
authors.forename: Moira
authors.initials: M
authors.lastname: Chan-Yeung
authors.forename: Cheuk-Ming
authors.initials: CM
authors.lastname: Tam
authors.forename: Harriet
authors.initials: H
authors.lastname: Wong
authors.forename: Chi-Chiu
authors.initials: CC
authors.lastname: Leung
authors.forename: Julie
authors.initials: J
authors.lastname: Wang
authors.forename: Wing-Wai
authors.initials: WW
authors.lastname: Yew
authors.forename: Chak-Wah
authors.initials: CW
authors.lastname: Lam
authors.forename: Kai-Man
authors.initials: KM
authors.lastname: Kam
mesh_terms: D004251:DNA Transposable Elements; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011159:Population Surveillance; D011446:Prospective Studies; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D004251:DNA Transposable Elements