Optical coherence tomography findings in nicotinic acid maculopathy.
OBJECTIVE
To report optical coherence tomography findings in nicotinic acid maculopathy.


METHODS
Observational case report.


METHODS
The patient was examined with ophthalmoscopy, fluorescein angiography, and optical coherence tomography.


RESULTS
A 71-year-old man presented with bilateral decreased visual acuity with metamorphopsia. Optical coherence tomography demonstrated cystoid spaces in the outer plexiform layer and inner nuclear layer. Fluorescein angiography did not show leakage. Two weeks after stopping the nicotinic acid, the cystoid spaces resolved.


CONCLUSIONS
Niacin maculopathy causes cystoid spaces in the inner nuclear and outer plexiform layers that resolve with discontinuation of the drug.
Spirn
Marc J
MJ
LuEsther T. Mertz Retina Research Laboratory, Manhattan Eye, Ear, and Throat Hospital, New York, New York 10021, USA.
Warren
Floyd A
FA
Guyer
David R
DR
Klancnik
James M
JM
Spaide
Richard F
RF
D000368:Aged; D005451:Fluorescein Angiography; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000009:adverse effects*; D007368:Interferometry; D008027:Light; D008297:Male; D009525:Niacin / Q000009:adverse effects*; D009887:Ophthalmoscopy; D012160:Retina / Q000187:drug effects* / Q000473:pathology; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D014054:Tomography; D014786:Vision Disorders / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D014792:Visual Acuity / Q000187:drug effects
D000960:Hypolipidemic Agents; D009525:Niacin