Functional genomics and proteomics in control of breathing.
New genomic and proteomic techniques offer remarkable promise as tools to address longstanding questions regarding molecular mechanisms involved in the control of breathing. Here, these techniques are described. Additionally, recent examples of the application of these and related molecular techniques are provided-particularly including observations regarding the role of S-nitrosylation signaling reactions in regulating ventilatory responses.
Gaston
Benjamin
B
Pediatric Respiratory Medicine, University of Virginia Health System, Post Office Box 800386, Charlottesville, VA 22908, USA. bmg3g@virginia.edu
D000818:Animals; D023281:Genomics / Q000379:methods*; D051379:Mice; D018345:Mice, Knockout; D010597:Pharmacogenetics; D040901:Proteomics / Q000379:methods*; D012123:Pulmonary Ventilation / Q000235:genetics / Q000502:physiology; D051381:Rats; D012119:Respiration / Q000235:genetics*; D026403:S-Nitrosothiols / Q000378:metabolism
D026403:S-Nitrosothiols