Salivary duct carcinoma of the larynx: report of a rare case.
Salivary duct carcinomas are primarily high-grade, aggressive malignancies that affect men in the fifth and sixth decades of life. These tumors are usually found in the major salivary glands; rarely do they originate in the minor salivary glands. The distinctive feature of these neoplasms is their remarkable histologic resemblance to infiltrating ductal carcinomas of the mammary gland; both types of tumor feature epithelial and myoepithelial cells arrayed in solid, papillary, and cribriform patterns. To the best of our knowledge, only one case of a primary salivary duct carcinoma of the larynx has been previously reported. In this article, we describe a new case, and we review the literature on salivary duct carcinomas.
Goel
Madhu M
MM
Department of Pathology, King George's Medical College, Lucknow-226004, Uttar Pradesh, India. madhukgmc@rediffmail.com
Agrawal
Satya P
SP
Srivastava
Anand N
AN
D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D035583:Rare Diseases; D018570:Risk Assessment; D018987:Salivary Ducts / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome