title: Oral epithelial dysplasia: clinical characteristics of western European residents.
abstract: To detail the clinical presentation of oral epithelial dysplasia in a large cohort of residents in western Europe. Descriptive statistical analysis of the data were calculated using chi-square and Fisher's exact tests. Oral epithelial dysplasia manifested typically as a white or mixed red and white lesion on the tongue, buccal mucosa or floor of mouth. The peak age of presentation of oral epithelial dysplasia was the 6th decade. Most clinically detected lesions had only mild oral epithelial dysplasia. Although uncommon, lesions with severe dysplasia were most likely to arise on the floor of mouth or lateral border of tongue. Oral epithelial dysplasia is likely to manifest as a solitary white patch, but it is not possible to accurately predict the likely degree of dysplasia from the clinical features of such lesions.
authors.affiliation: Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, UCL, University of London, 256 Gray's Inn Road, London WC1X 8LD, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Jaber
authors.forename: S R
authors.initials: SR
authors.lastname: Porter
authors.forename: P
authors.initials: P
authors.lastname: Speight
authors.forename: J W
authors.initials: JW
authors.lastname: Eveson
authors.forename: C
authors.initials: C
authors.lastname: Scully
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D001208:Asia / Q000208:ethnology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002610:Cheek; D016009:Chi-Square Distribution; D015331:Cohort Studies; D004739:England; D006801:Humans; D007971:Leukoplakia / Q000473:pathology; D008875:Middle Aged; D009060:Mouth Floor; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000208:ethnology / Q000473:pathology*; D019226:Oral Ulcer / Q000473:pathology; D011230:Precancerous Conditions / Q000208:ethnology / Q000473:pathology*; D017678:Sex Distribution; D014062:Tongue Neoplasms / Q000473:pathology