title: [Pathophysiology solves key questions in the therapy of type 2 diabetes mellitus].
abstract: Pathophysiological mechanisms accompanying Type 2 diabetes mellitus are the basement for the rational therapy of this disease. The finding of the relationship between impaired insulin secretion and its action including the regulatory mechanisms is of importance for successful treatment. In a review article there are included the most important pathways influencing therapeutical considerations in clinical practice.
authors.affiliation: III. interní klinika 1. lékarské fakulty UK a VFN, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Skrha
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D007328:Insulin / Q000502:physiology
chemical_list: D007328:Insulin