Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis.
Minokoshi
Yasuhiko
Y
Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA.
Kahn
C Ronald
CR
Kahn
Barbara B
BB
D017667:Adipocytes / Q000378:metabolism; D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D005947:Glucose / Q000378:metabolism; D051275:Glucose Transporter Type 4; D006720:Homozygote; D007328:Insulin / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D008954:Models, Biological; D009004:Monosaccharide Transport Proteins / Q000235:genetics / Q000502:physiology*; D009124:Muscle Proteins; D009132:Muscles / Q000378:metabolism; D011972:Receptor, Insulin / Q000235:genetics / Q000502:physiology*; D013997:Time Factors
D051275:Glucose Transporter Type 4; D007328:Insulin; D009004:Monosaccharide Transport Proteins; D009124:Muscle Proteins; C495693:Slc2a4 protein, mouse; D011972:Receptor, Insulin; D005947:Glucose