Blood and hair lead levels in boys and girls living in two Sardinian towns at different risks of lead pollution.
This study reports blood and hair lead levels measured in 1998 in 222 children from two Sardinian towns: Portoscuso and Sestu. Portoscuso is in a polluted area of Sardinia due to its vicinity to the industrial zone of Portovesme. As a consequence of its economy and location, Sestu is not exposed to lead pollution. Blood lead (PbB) concentration was determined in heparinized venous blood samples by graphite furnace atomic absorption spectrophotometry (AAS). Hair lead (PbH) concentration was determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). With respect to blood lead levels, the boys of Portoscuso have the highest arithmetic mean value (11.30 microg/dL), followed by the Portoscuso girls (7.39 microg/dL); they are followed, but with much lower values, by the boys (4.09 microg/dL) and girls (3.34 microg/dL) of Setsu. For hair lead levels, the Portoscuso boys have the highest arithmetic mean value (15.51 microg/g), followed by the Portoscuso girls (8.82 microg/g) and the Sestu boys (4.03 microg/g) and girls (2.83 microg/g). Therefore the mean values of PbB and PbH follow similar patterns in the boys and girls of the two Sardinian towns. Two-way ANOVA reveals a significant effect of sex and town on log PbB and log PbH. Moreover, values of the Bravais-Pearson coefficients of correlation between log PbB and log PbH are statistically significant for the total sample (r=0.5086; P<0.001), for males (r=0.4275; P<0.01), and for females (r=0.4859, P<0.001). The sensitivity of the hair lead analysis in identifying lead concentrations above 10 microg/g is 49%. The results support the hypothesis that hair lead levels can be considered an indicator of different relative exposure of populations to lead pollution.
Sanna
Emanuele
E
Dipartimento di Biologia Sperimentale, Sezione di Scienze Antropologiche, Università degli Studi di Cagliari, Cittadella Universitaria, SS 554 (km 4.5), Monserrato 09042 (CA), Italy. sannae@vaxcal.unica.it
Liguori
Alessandra
A
Palmas
Lucia
L
Soro
Maria Renata
MR
Floris
Giovanni
G
D002648:Child; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000032:analysis / Q000097:blood*; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007221:Industry; D007558:Italy; D007854:Lead / Q000032:analysis / Q000097:blood*; D008297:Male; D012680:Sensitivity and Specificity; D012737:Sex Factors
D004785:Environmental Pollutants; D007854:Lead