title: Hypophysopexy technique for radiosurgical treatment of cavernous sinus pituitary adenoma.
abstract: Stereotactic radiosurgery is being used with increased frequency in the treatment of residual or recurrent pituitary adenomas. The major risk associated with radiosurgical treatment of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation of the pituitary, which frequently leads to the development of hypopituitarism. The authors describe a technique of pituitary transposition to reduce the radiation dose to the normal pituitary gland in cases of planned radiosurgical treatment of residual pituitary adenoma within the cavernous sinus. A sellar exploration for tumor resection is performed, the pituitary gland is transposed from the region of the cavernous sinus, and a fat and fascia graft is interposed between the normal pituitary gland and the residual tumor in the cavernous sinus. The residual tumor may then be treated with stereotactic radiosurgery. The increased distance between the normal pituitary gland and the residual tumor facilitates treatment of the tumor with radiosurgery and reduces the radiation to the normal pituitary gland. An illustrative case of a young female with recurrent acromegaly and a pituitary adenoma invading the cavernous sinus is described.
authors.affiliation: Department of Neurosurgery, The University of Utah, Salt Lake City, UT 84132-2303, USA. william.couldwell@hsc.utah.edu
authors.forename: William T
authors.initials: WT
authors.lastname: Couldwell
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Rosenow
authors.forename: Richard L
authors.initials: RL
authors.lastname: Rovit
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Benzil
mesh_terms: D000172:Acromegaly / Q000601:surgery; D000236:Adenoma / Q000601:surgery*; D002426:Cavernous Sinus; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications; D016634:Radiosurgery / Q000379:methods*