Trypan blue-assisted peeling of the internal limiting membrane during macular hole surgery.
OBJECTIVE
To evaluate the outcome of surgeries for macular holes using trypan blue to facilitate delamination of the internal limiting membrane.


METHODS
A retrospective series of 18 patients.


METHODS
All patients underwent a three-port pars plana vitrectomy with internal limiting membrane delamination using trypan blue 0.06% to assist visualization. The main outcome measures were postoperative visual acuity and clinically evident retinal pigment epithelial changes.


RESULTS
The median preoperative visual acuity was 20/200, and the median postoperative visual acuity was 20/70. All but one macular hole were closed after surgery (94%). At the last recorded follow-up, 10 patients (56%) had improved visual acuity of at least two chart lines. No adverse reaction related to trypan blue was observed up to 1 year postsurgery.


CONCLUSIONS
Trypan blue staining of internal limiting membrane may accomplish more complete dissections of the internal limiting membrane and better surgical and visual outcomes.
Perrier
Manuel
M
Ophthalmology Department, Centre Hospitalier Université de Montréal-Pavillon Notre-Dame, Montréal, Québec, Canada. perrier.manuel@sympatico.ca
Sébag
Mikaël
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D019773:Epiretinal Membrane / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000601:surgery*; D012189:Retrospective Studies; D013194:Staining and Labeling / Q000379:methods; D014343:Trypan Blue; D014792:Visual Acuity; D014821:Vitrectomy
D004396:Coloring Agents; D014343:Trypan Blue