Metastatic pulmonary ameloblastoma. An unusual case.
We present a patient who had a large metastatic pulmonary ameloblastoma resected 25 years after removal of an apparently benign primary ameloblastoma of the jaw. It highlights three areas: problems with the histopathological diagnosis of pulmonary metastases using fine needle aspiration; a noted radiological improvement after a 5-year course of oral cyclophosphamide, in keeping with occasional patients who have responded to chemotherapy; and the technical difficulties of resection of a large pulmonary metastasis, particularly when it is adherent to the mediastinum.
Campbell
D
D
Department of Orthopaedic Surgery, Ninewells Hospital, Dundee, UK.
Jeffrey
R R
RR
Wallis
F
F
Hulks
G
G
Kerr
K M
KM
D000564:Ameloblastoma / Q000473:pathology / Q000556:secondary*; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D013997:Time Factors
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide