title: Emerging evidence on the role of soy in reducing prostate cancer risk.
abstract: Soyfoods are a unique dietary source of isoflavones, which have both hormonal and non-hormonal effects relevant to prostate cancer prevention. In vitro, the main soybean isoflavone, genistein, inhibits prostate cancer cell growth; in animals, most but not all studies show isoflavonel rich soy protein and isolated isoflavones inhibit prostate tumor development. Currently, although only limited epidemiologic data indicate soy intake reduces prostate cancer risk, results from a pilot intervention trial suggest isoflavones may be beneficial to prostate cancer patients. For several reasons, men concerned about their prostate health may consider incorporating soy into their diet.
authors.affiliation: Nutrition Matters, Inc., Port Townsend, WA 98368, USA.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Messina
mesh_terms: D000368:Aged; D000818:Animals; D006801:Humans; D066298:In Vitro Techniques; D007529:Isoflavones / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000209:etiology* / Q000517:prevention & control*; D051381:Rats; D012307:Risk Factors; D013025:Glycine max
chemical_list: D007529:Isoflavones