[Cardiac complications of anorexia nervosa].
The death rate of anorexia nervosa (AN) patients is up to 30 times greater than that of age-matched normal women. Bradycardia, hypotension and mitral valve prolapse are cardiac abnormalities that can be frequently found in AN patients. Risk of death is substantially linked to QT prolongation, which could be due to hypokalemia (binge/purging type AN) or to a starvation-derived anatomical remodelling of the heart (restricting type AN). The principal risk factors are duration of illness > 10 years, chronic hypokalemia, plasmatic albumin chronically < 3.6 g/dl and absolute QT > or = 600 ms.
Ravaldi
Claudia
C
cravald@libero.it
Vannacci
Alfredo
A
Ricca
Valdo
V
D000137:Acid-Base Imbalance / Q000150:complications / Q000209:etiology; D000856:Anorexia Nervosa / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D016757:Death, Sudden, Cardiac / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008945:Mitral Valve Prolapse / Q000150:complications* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D009748:Nutrition Disorders / Q000150:complications / Q000209:etiology