The management of idiopathic olfactory hallucinations: a study of two patients.
OBJECTIVE
Idiopathic olfactory hallucination is a rare condition. We report two cases of idiopathic olfactory hallucination and a review of the literature that relates to this condition.


METHODS
A retrospective case study of two patients with idiopathic olfactory hallucination.


METHODS
Records of two patients were retrospectively reviewed.


RESULTS
The diagnosis of idiopathic olfactory hallucination was confirmed after excluding any intranasal disease or any central nervous system disorder discernible by an electroencephalogram and magnetic resonance imaging. Both patients were successfully treated with sodium valproate. One patient stopped taking sodium valproate because of side effects, only for the symptoms to return, but these were then controlled by phenytoin sodium. The mean patient follow-up time was 3 years 5 months.


CONCLUSIONS
The symptoms of some cases of idiopathic olfactory hallucination may be controlled by sodium valproate or phenytoin sodium. We hypothesize that this disorder may be a central phenomenon attributable to reverberating circuits.
Majumdar
S
S
University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK.
Jones
N S
NS
McKerrow
W S
WS
Scadding
G
G
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D005260:Female; D006212:Hallucinations / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D010672:Phenytoin / Q000627:therapeutic use*; D012189:Retrospective Studies; D014635:Valproic Acid / Q000627:therapeutic use*
D000927:Anticonvulsants; D014635:Valproic Acid; D010672:Phenytoin