HIV-2 subtype circulating in India (south).
The genetic types and subtypes of HIV vary from region to region. This study looked at the relative prevalence of HIV-2 subtypes in south India. Nucleotide sequencing of the HIV-2 envelope V3 region of strains from 11 individuals infected with HIV-2 and one individual who had dual infection with HIV-1 and HIV-2 was performed. Phylogenetic analysis showed that all individuals were infected with HIV-2 subtype A. These strains were from individuals who live in different regions of south India. In all, up to present, 17 strains inclusive of the authors' 12 have been sequenced, and subtype A of HIV-2 is seen in both monoinfections and dual infections with HIV-1 in India.
Kannangai
Rajesh
R
Department of Clinical Virology, Christian Medical College Hospital, Vellore-632 004, India.
Shaji
Ramachandran V
RV
Ramalingam
Sandeep
S
Jesudason
Mary V
MV
Abraham
Oriapadickal C
OC
George
Renu
R
Shanmugam
Arvindh P
AP
Schwartz
David H
DH
Sridharan
Gopalan
G
D000328:Adult; D005260:Female; D015699:HIV Envelope Protein gp120 / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology*; D015498:HIV-2 / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics; D010802:Phylogeny
D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments