title: Generalized acanthosis nigricans in an otherwise healthy young child.
abstract: Acanthosis nigricans in children is usually a benign condition most commonly associated with obesity. Generalized acanthosis nigricans is a very rare condition, especially in childhood. We report a 6-year-old boy with a 4-year history of generalized hyperpigmentation and velvety thickening of the skin. Despite an extensive examination, no evidence for an underlying neoplastic or endocrinologic disease was found.
authors.affiliation: Department of Dermatology, Columbia Presbyterian Medical Center, Columbia University, New York, New York 10032, USA.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Uyttendaele
authors.forename: Tamara
authors.initials: T
authors.lastname: Koss
authors.forename: Bita
authors.initials: B
authors.lastname: Bagheri
authors.forename: Paul
authors.initials: P
authors.lastname: Schneiderman
authors.forename: Miriam E
authors.initials: ME
authors.lastname: Silfen
authors.forename: Mary P
authors.initials: MP
authors.lastname: Gallagher
authors.forename: Maria
authors.initials: M
authors.lastname: Garzon
authors.forename: Danielle
authors.initials: D
authors.lastname: Engler
mesh_terms: D000052:Acanthosis Nigricans / Q000473:pathology* / Q000503:physiopathology; D000367:Age Factors; D001707:Biopsy, Needle; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index