Channeling phage DNA through membranes: from in vivo to in vitro.
We discuss current models of phage DNA transport through membranes. We present results that attempt to answer the following questions: is there a single mechanism of transport for all types of phage? is DNA transported as a free molecule or in association with proteins? what is the driving force for transport?
Letellier
Lucienne
L
Institut de Biochimie et Biophysique Moléculaire et Cellulaire, UMR CNRS 8619, Université Paris Sud, Bat 430, 91405 cedex, Orsay, France. lucienne.letellier@biomemb.u-psud.fr
Boulanger
Pascale
P
de Frutos
Marta
M
Jacquot
Pierre
P
D001425:Bacterial Outer Membrane Proteins / Q000502:physiology; D001435:Bacteriophages / Q000235:genetics* / Q000502:physiology; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000502:physiology; D020409:Molecular Motor Proteins / Q000502:physiology; D011991:Receptors, Virus / Q000502:physiology; D019065:Virus Assembly / Q000502:physiology
D001425:Bacterial Outer Membrane Proteins; D004279:DNA, Viral; D029968:Escherichia coli Proteins; C050900:FhuA protein, E coli; D020409:Molecular Motor Proteins; D011991:Receptors, Virus