[A case report of tongue squamous cell carcinoma showing a complete response to TS-1].
A 75-year-old female with squamous cell carcinoma in the left margin of the tongue (T2N0M0) was referred to our hospital. She was treated with oral administration TS-1 80 mg/day as preoperative chemotherapy. After commencement of TS-1 administration, the tumor size was reduced at 1 week and had disappeared clinically at 4 weeks. Oral administration of TS-1 was done in 2 courses at the same dose. After two courses, histological examination reveled a complete disappearance of the cancer cells. No adverse effects were seen during the treatment period. She remains under oral administration of UFT for maintenance chemotherapy and there is no evidence of recurrence of the tumor.
Ikeda
Hisazumi
H
Dept. of Developmental and Reconstructive Medicine, Division of Oral and Maxillofacial Surgical Reconstruction and Functional Restoration, Nagasaki University Graduate School of Biomedical Sciences, Course of Medical and Dental Science.
Takebe
Yoshiaki
Y
Irie
Akihiko
A
Mizoguchi
Yuji
Y
Yamada
Keiko
K
Shibahara
Kiyotaka
K
Inokuchi
Tsugio
T
D000284:Administration, Oral; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006801:Humans; D010094:Oxonic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D011725:Pyridines / Q000008:administration & dosage / Q000627:therapeutic use*; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use*; D014062:Tongue Neoplasms / Q000188:drug therapy*; D014498:Uracil / Q000008:administration & dosage
D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D004338:Drug Combinations; D011725:Pyridines; C096910:UFT(R) drug; C079198:S 1 (combination); D005641:Tegafur; D014498:Uracil; D010094:Oxonic Acid