title: Minocycline-induced staining of torus palatinus and alveolar bone.
abstract: BACKGROUND
  Minocycline hydrochloride, an analog of tetracycline, is widely used in the treatment of acne. Its use has been associated with discoloration of teeth, bone, and other tissues.
  
  
  METHODS
  A case is presented involving a patient with minocycline-induced staining of the torus palatinus and alveolar bone.
  
  
  RESULTS
  No treatment was rendered since the patient was not concerned with the appearance of the discoloration. The patient's dermatologist elected to change antibiotics.
  
  
  CONCLUSIONS
  Patients on long-term minocycline therapy should be made aware of the possibility of pigmentation of bone and soft tissue that may be reversible with discontinuation of therapy; however, minocycline-induced staining of the permanent dentition may not be reversible.
authors.affiliation: Periodontics, Department of Dental Specialties, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Lilibeth
authors.initials: L
authors.lastname: Ayangco
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Sheridan
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000539:Alveolar Process / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005096:Exostoses / Q000473:pathology*; D005260:Female; D006801:Humans; D008439:Maxillary Diseases / Q000473:pathology*; D008911:Minocycline / Q000009:adverse effects*; D010159:Palate / Q000187:drug effects*; D010859:Pigmentation Disorders / Q000139:chemically induced*
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline