Generalized acanthosis nigricans in an otherwise healthy young child.
Acanthosis nigricans in children is usually a benign condition most commonly associated with obesity. Generalized acanthosis nigricans is a very rare condition, especially in childhood. We report a 6-year-old boy with a 4-year history of generalized hyperpigmentation and velvety thickening of the skin. Despite an extensive examination, no evidence for an underlying neoplastic or endocrinologic disease was found.
Uyttendaele
Hendrik
H
Department of Dermatology, Columbia Presbyterian Medical Center, Columbia University, New York, New York 10032, USA.
Koss
Tamara
T
Bagheri
Bita
B
Schneiderman
Paul
P
Silfen
Miriam E
ME
Gallagher
Mary P
MP
Garzon
Maria
M
Engler
Danielle
D
D000052:Acanthosis Nigricans / Q000473:pathology* / Q000503:physiopathology; D000367:Age Factors; D001707:Biopsy, Needle; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index