Reninoma treated with nephron-sparing surgery.
A 14-year-old hypertensive boy was evaluated in our clinic. The physical examination was essentially normal except for his high blood pressure. Laboratory findings showed increased plasma renin activity. Abdominal ultrasonography detected a hypoechoic, 2-cm mass in right kidney. Contrast-enhanced computed tomography of the abdomen revealed a well-circumscribed, solid, hypoenhancing cortical lesion in the middle of the right kidney. Magnetic resonance angiography documented bilateral normal renal arteries. With a preoperative diagnosis of reninoma, the patient underwent nephron-sparing surgery. Intraoperative frozen section analysis revealed a benign lesion. Subsequently, histopathologic examination and electron microscopy confirmed the diagnosis of juxtaglomerular cell tumor. The patient remained normotensive in the postoperative period. Follow-up intravenous urography showed bilateral normally functioning kidneys.
Mete
Uttam K
UK
Department of Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Niranjan
J
J
Kusum
Joshi
J
Rajesh
L S
LS
Goswami
A K
AK
Sharma
S K
SK
D000230:Adenocarcinoma / Q000150:complications / Q000378:metabolism / Q000601:surgery*; D000293:Adolescent; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology; D007680:Kidney Neoplasms / Q000150:complications / Q000378:metabolism / Q000601:surgery*; D008297:Male; D009399:Nephrons / Q000601:surgery*; D012083:Renin / Q000378:metabolism
D012083:Renin