[Distribution of the Xvent-2 mRNA between informosomes and polysomes in early frog development].
Translational expression regulation was studied for Xvent-2 coding for a transcription factor involved in dorsoventral differentiation of amphibian embryos. The Xvent-2 mRNA was detected predominantly in informosomes at all developmental stages examined, and only its minor fraction was associated with polysomes. Expression of Xvent-2 was assumed to be regulated at the translational level, with Xvent-2 produced immediately before polypotent cells enter a certain differentiation pathway.
Voronina
A S
AS
Bakh Institute of Biochemistry, Russian Academy of Sciences, Moscow, 119071 Russia. voronina@inbi.ras.ru
Pshennikova
E S
ES
Shatilov
D V
DV
D000818:Animals; D003593:Cytoplasm / Q000737:chemistry / Q000235:genetics; D004625:Embryo, Nonmammalian; D005260:Female; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D008297:Male; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D011896:Rana temporaria / Q000196:embryology* / Q000235:genetics; D014157:Transcription Factors; D029867:Xenopus Proteins
D018398:Homeodomain Proteins; D012333:RNA, Messenger; D014157:Transcription Factors; D029867:Xenopus Proteins; C099992:ventx2.1 protein, Xenopus