title: Medication adherence in pediatric asthma: reasoning, responsibility, and behavior.
abstract: OBJECTIVE
  To assess child adherence to preventive asthma medications; to investigate relations between knowledge, reasoning about asthma, and responsibility for management and adherence; and to determine the association between adherence and morbidity.
  
  
  METHODS
  Participants were 106 children with asthma and their parents. Medication adherence was electronically monitored for 1 month. Participants completed self-report measures. Children were interviewed to assess reasoning about asthma.
  
  
  RESULTS
  Children's adherence was approximately 48% of prescribed doses. Adherence was negatively related to age (r = -.21, p <.05); minority status, F(1, 98) = 7.55, p <.01; and morbidity (r = -.26, p <.01). Age was associated with increased child knowledge (r =.47, p <.001), reasoning about asthma (tau =.23, p <.01), and responsibility for asthma management (r =.44, p <.01). These variables were not associated with adherence.
  
  
  CONCLUSIONS
  Although older children know more about asthma and assume more responsibility for disease management, their adherence is lower than that of younger children. No association was found between adherence and child knowledge, reasoning about asthma, or responsibility for asthma management.
authors.affiliation: Child Psychiatry, Rhode Island Hospital, 593 Eddy Street, Providence, Rhode Island 02903, USA. emcquaid@lifespan.org
authors.forename: Elizabeth L
authors.initials: EL
authors.lastname: McQuaid
authors.forename: Sheryl J
authors.initials: SJ
authors.lastname: Kopel
authors.forename: Robert B
authors.initials: RB
authors.lastname: Klein
authors.forename: Gregory K
authors.initials: GK
authors.lastname: Fritz
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000175:diagnosis / Q000517:prevention & control*; D001294:Attitude to Health; D002648:Child; D003657:Decision Making; D005260:Female; D015438:Health Behavior; D006801:Humans; D008297:Male; D010349:Patient Compliance; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D018927:Anti-Asthmatic Agents