Panhypopituitarism induced by cholesterol granuloma in the sellar region--case report.
A 67-year-old man with generalized fatigue and weight loss developed hyponatremia. Endocrinologic examination demonstrated panhypopituitarism. Magnetic resonance imaging showed a pituitary mass extending slightly to the suprasellar region. Transsphenoidal resection of the tumor was performed. Histological examination found exclusively granulomatous tissue with cholesterol clefts, and no epithelial component. This cholesterol granuloma may be classified as xanthogranuloma of the sellar region.
Yonezawa
Kazuki
K
Division of Neurosurgery, Himeji Daiichi Hospital, Himeji, Hyogo, Japan.
Shirataki
Kunio
K
Sakagami
Yoshio
Y
Kohmura
Eiji
E
D000368:Aged; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006099:Granuloma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D012658:Sella Turcica / Q000473:pathology / Q000601:surgery; D014973:Xanthomatosis / Q000150:complications* / Q000473:pathology / Q000601:surgery