title: The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
authors.affiliation: Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg 11, 37 077 Göttingen, Germany. taco@nmr.mpibpc.mpg.de
authors.forename: Teresa
authors.initials: T
authors.lastname: Carlomagno
authors.forename: Marcel J J
authors.initials: MJ
authors.lastname: Blommers
authors.forename: Jens
authors.initials: J
authors.lastname: Meiler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Jahnke
authors.forename: Thomas
authors.initials: T
authors.lastname: Schupp
authors.forename: Frank
authors.initials: F
authors.lastname: Petersen
authors.forename: Dieter
authors.initials: D
authors.lastname: Schinzer
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Altmann
authors.forename: Christian
authors.initials: C
authors.lastname: Griesinger
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry*; D002417:Cattle; D034261:Epothilones / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012996:Solutions / Q000737:chemistry; D013329:Structure-Activity Relationship; D014404:Tubulin / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D034261:Epothilones; D012996:Solutions; D014404:Tubulin; C093787:epothilone A