Enantioselective Michael reaction catalyzed by well-defined chiral ru amido complexes: isolation and characterization of the catalyst intermediate, ru malonato complex having a metal-carbon bond.
Chiral Ru amido complexes promote asymmetric Michael addition of malonates to cyclic enones, leading to Michael adducts with excellent ee's, in which the chiral Ru amido complexes react with malonates to give isolable catalyst intermediates, chiral Ru malonato complexes bearing a metal bound C-nucleophile.
Watanabe
Masahito
M
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology and Frontier Collaborative Research Center, Ookayama, Meguro-ku, Tokyo 152-8552 Japan.
Murata
Kunihiko
K
Ikariya
Takao
T