Nationwide surveillance for Staphylococcus aureus with reduced susceptibility to vancomycin in Korea.
Methicillin-resistant Staphylococcus aureus (MRSA) accounts for more than 70% of S. aureus isolates from tertiary hospitals in Korea. Clinical isolates of S. aureus were collected from eight provincial, university-affiliated hospitals during the period from June 1999 to January 2001 for nationwide surveillance. All isolates were screened for reduced susceptibility to vancomycin by using brain heart infusion agar containing 4 micro g of vancomycin per milliliter. Population analysis and the determination of the MIC of vancomycin were done for the isolates which grew on the screening agar plates. Of 682 total isolates, MRSA accounted for 64% (439 of 682). Of 27 (4%) isolates that grew on the screening agar plates, none showed the heteroresistance phenotype. No strains with reduced susceptibility to vancomycin were identified.
Kim
Hong Bin
HB
Department of Internal Medicine, Seoul National University College of Medicine, Republic of Korea.
Park
Wan Beom
WB
Lee
Ki Deok
KD
Choi
Young Joo
YJ
Park
Sang Won
SW
Oh
Myoung-Don
MD
Kim
Eui-Chong
EC
Choe
Kang Won
KW
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006785:Hospitals, University; D006801:Humans; D007723:Korea; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology; D020713:Vancomycin Resistance
D000900:Anti-Bacterial Agents; D014640:Vancomycin