title: Embolisation of intracranial meningiomas without subsequent surgery.
abstract: In an open, prospective study, we embolised intracranial meningiomas in seven patients, without subsequent surgery. Follow-up over a mean of 20 months included serial neurological examination, MRI and MR spectroscopy. Clinically, embolisation had no adverse effects. Symptomatic patients showed clinical improvement. On MRI marked tumour shrinkage occurred after embolisation in six patients, and was most pronounced during the first 6 months. In a young boy the tumour was unchanged despite complete angiographic devascularisation. Embolisation without subsequent surgery may cause substantial tumour shrinkage and thus be used in selected in patients. However, thorough follow-up is mandatory to ascertain the effects of embolisation.
authors.affiliation: Department of Neuroradiology, University of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. bendszus@neuroradiologie.uni-wuerzburg.de
authors.forename: M
authors.initials: M
authors.lastname: Bendszus
authors.forename: I
authors.initials: I
authors.lastname: Martin-Schrader
authors.forename: H P
authors.initials: HP
authors.lastname: Schlake
authors.forename: L
authors.initials: L
authors.lastname: Solymosi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000409:Alanine / Q000378:metabolism; D000792:Angiography; D002648:Child; D002794:Choline / Q000378:metabolism; D003401:Creatine / Q000378:metabolism; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008579:Meningioma / Q000150:complications / Q000628:therapy*; D008875:Middle Aged; D009460:Neurologic Examination; D011183:Postoperative Complications; D011446:Prospective Studies
chemical_list: D003401:Creatine; D002794:Choline; D000409:Alanine