title: Allele and haplotype frequencies of Y-short tandem repeat loci in Turkey.
abstract: OBJECTIVE
  To assess the frequency distribution of six Y-chromosomal specific short tandem repeat (STR) polymorphisms and frequencies of haplotypes in Turkish population.
  
  
  METHODS
  Blood samples were taken from 200 unrelated Turkish men from different regions of Turkey, who were involved in legal proceedings concerning paternity. The DNA was amplified and typed by use of Y-Plex 6 kit containing 6 Y-STR markers (DYS393, DYS19, DYS389 II, DYS390, DYS391, and DYS385). Capillary electrophoresis was carried out on an ABI 310 Genetic Analyzer.
  
  
  RESULTS
  Allele frequency profiles of the Turkish men showed no significant differences compared with previously published results for Swiss and German populations. The range of gene diversity was determined between 48.3% for DYS391 and 96.0% for DYS385. Of 184 determined haplotypes, 170 occurred once, and the rest more than once. The most common haplotypes had a frequency of 1.5%.
  
  
  CONCLUSIONS
  High degree of haplotype diversity in Turkish population makes analysis of Y-STRs a useful tool in forensic cases.
authors.affiliation: Department of Biology, Council of Forensic Medicine, Ministry of Justice, Adli Tip Kurumu Başkanligi, Esekapi-Cerrahpaşa, Istanbul, Turkey. fasicioglu@hotmail.com
authors.forename: Faruk
authors.initials: F
authors.lastname: Aşicioglu
authors.forename: Fatih
authors.initials: F
authors.lastname: Akyüz
authors.forename: Umit
authors.initials: U
authors.lastname: Cetinkaya
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Canli
mesh_terms: D041322:Chromosomes, Human, Y / Q000235:genetics*; D005554:Forensic Medicine; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences; D014421:Turkey