title: Myelogenous leukemia in a bearded dragon (Acanthodraco vitticeps).
abstract: A 3-yr-old bearded dragon (Acanthodraco vitticeps) presented with lethargy, a swollen right elbow joint, inability to move its rear limbs normally, and marked leukocytosis. The majority of leukocytes were an abnormal mononuclear lymphoid-type cell with a high nuclear to cytoplasmic ratio, a slightly blue cytoplasm, nuclei with coarsely granular chromatin, and some nuclear clefts. Acute leukemia of lymphoid or myeloid origin was tentatively diagnosed. The abnormal mononuclear leukocyte cell population stained positively for the myeloid cytochemical stains: peroxidase, chloroacetate esterase, and L1-calprotectin. The abnormal cell population of the peripheral blood did not stain with the lymphoid cytochemical stains: alpha-naphthyl butyrate esterase, CD3, and CD79a.
authors.affiliation: Houston Zoological Gardens, 1513 North MacGregor Street, Houston, Texas 77030, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Tocidlowski
authors.forename: P L
authors.initials: PL
authors.lastname: McNamara
authors.forename: J W
authors.initials: JW
authors.lastname: Wojcieszyn
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001797:Blood Protein Electrophoresis / Q000662:veterinary; D001798:Blood Proteins / Q000032:analysis; D003937:Diagnosis, Differential; D006403:Hematologic Tests / Q000662:veterinary; D006651:Histocytochemistry / Q000662:veterinary; D007951:Leukemia, Myeloid / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D007962:Leukocytes / Q000166:cytology / Q000473:pathology*; D007964:Leukocytosis / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D008116:Lizards; D008297:Male; D013194:Staining and Labeling
chemical_list: D001798:Blood Proteins