Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats.
Marchand
Fabien
F
INSERM/UdA E 9904, Laboratoire de Pharmacologie Médicale, Faculté de Médecine, 63001 Clermont-Ferrand cedex 1, France Programa de Farmacología Molecular y Clínica, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile Departemento de Ciencas Biologicas, Facultad de Química y Biología, Universidad de Chile, Casilla 40, Correo 33, Santiago, Chile.
Alloui
Abdelkrim
A
Chapuy
Eric
E
Jourdan
Didier
D
Pelissier
Teresa
T
Ardid
Denis
D
Hernandez
Alejandro
A
Eschalier
Alain
A
D000700:Analgesics / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use; D003511:Cyclohexanols / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004791:Enzyme Inhibitors / Q000494:pharmacology; D010134:Fenclonine / Q000494:pharmacology; D008297:Male; D020422:Mononeuropathies / Q000188:drug therapy*; D009043:Motor Activity / Q000187:drug effects; D009270:Naloxone / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology; D010146:Pain / Q000188:drug therapy*; D017288:Pain Threshold / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000293:injuries; D000069470:Venlafaxine Hydrochloride; D014828:Vocalization, Animal / Q000187:drug effects; D019805:alpha-Methyltyrosine / Q000494:pharmacology
D000700:Analgesics; D000928:Antidepressive Agents; D003511:Cyclohexanols; D004791:Enzyme Inhibitors; D009292:Narcotic Antagonists; D009270:Naloxone; D019805:alpha-Methyltyrosine; D000069470:Venlafaxine Hydrochloride; D010134:Fenclonine