title: Antibiotic-loaded bone cement in orthopedic surgery.
abstract: Acrylic cement is used to secure implants to bone. When mixed with antibiotics or anticancer agents, acrylic cement slowly releases these agents while retaining its mechanical properties, thus providing specific in situ treatment.
authors.affiliation: Clinique Chirurgicale Orthopédique, CHU, Hôtel Dieu, 44093 cedex 1, Nantes, France. norbert.passuti@chu.nantes.fr
authors.forename: Norbert
authors.initials: N
authors.lastname: Passuti
authors.forename: François
authors.initials: F
authors.lastname: Gouin
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000737:chemistry; D001843:Bone Cements / Q000737:chemistry; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D009985:Orthopedics / Q000379:methods*; D019736:Prostheses and Implants
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D001843:Bone Cements; D003692:Delayed-Action Preparations; D004337:Drug Carriers