title: A critical evaluation of results of partial left ventriculectomy.
abstract: BACKGROUND
  Because of the variation in the surgical procedures designed to reduce ventricular radius, along with differences in hospital care, it is difficult to disentangle the factors that may contribute to the success or failure of the partial left ventriculectomy.
  
  
  RESULTS
  We undertook partial left ventriculectomy in 18 patients, 10 suffering from idiopathic dilated cardiomyopathy and 8 from ischemic heart disease. We assessed the amount of reduction in wall stress, the systolic thickening of the ventricular wall, and the extent of connective tissue in the excised segment of the wall. Of the overall group, six patients died, three from infarction, one of stroke, one with asystole, and one with ventricular fibrillation. The mean decrease in measured mesh tension was 40% (p < 0.001). Most patients exhibited improvements postoperatively in terms of the systolic thickening of the posterior and superior free walls of the left ventricle. In those in whom the events could be monitored, life-threatening arrhythmias posed complications in three of four patients with ischemic heart disease, and in two of six patients suffering from idiopathic dilated cardiomyopathy. In one patient, death was associated with a transmural alignment of fibrous tissue.
  
  
  CONCLUSIONS
  Our measured reductions in myocardial mesh tension were in keeping with the anticipated theoretical reduction in wall stress expected from partial ventriculectomy. The basic concept underscoring surgical maneuvers to reduce ventricular radius, therefore, is sound. A potential trap is the resection of the marginal artery. Critical myofibrosis was a rare complication. Arrhythmias, which are common, can successfully be treated by implantation of antitachycardic and defibrillatory devices.
authors.affiliation: Klinik und Poliklinik für Thorax, Herz und Gefèasschirurgie, University Münster, Germany. redmann@uni-muenster.de
authors.forename: P P
authors.initials: PP
authors.lastname: Lunkenheimer
authors.forename: K
authors.initials: K
authors.lastname: Redmann
authors.forename: D
authors.initials: D
authors.lastname: Kimaun
authors.forename: C W
authors.initials: CW
authors.lastname: Cryer
authors.forename: F
authors.initials: F
authors.lastname: Wübbeling
authors.forename: W
authors.initials: W
authors.lastname: Konertz
authors.forename: A
authors.initials: A
authors.lastname: Zytowsky
authors.forename: H
authors.initials: H
authors.lastname: Hotz
authors.forename: S Y
authors.initials: SY
authors.lastname: Ho
authors.forename: R H
authors.initials: RH
authors.lastname: Anderson
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006334:Heart Function Tests; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011336:Probability; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D015996:Survival Rate; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000601:surgery*