title: Points of regulation for auxin action.
abstract: There have been few examples of the application of our growing knowledge of hormone action to crop improvement. In this review we discuss what is known about the critical points regulating auxin action. We examine auxin metabolism, transport, perception and signalling and identify genes and proteins that might be keys to regulation, particularly the rate-limiting steps in various pathways. Certain mutants show that substrate flow in biosynthesis can be limiting. To date there is little information available on the genes and proteins of catabolism. There have been several auxin transport proteins and some elegant transport physiology described recently, and the potential for using transport proteins to manage free indole-3-acetic acid (IAA) concentrations is discussed. Free IAA is very mobile, and so while it may be more practical to control auxin action through managing the receptor and signalling pathways, the candidate genes and proteins through which this can be done remain largely unknown. From the available evidence, it is clear that the reason for so few commercial applications arising from the control of auxin action is that knowledge is still limited.
authors.affiliation: Institute of Experimental Botany, The Academy of Sciences of the Czech Republic, Rozvojová 135, 16502, Prague 6-Lysolaje, Czech Republic.
authors.forename: E
authors.initials: E
authors.lastname: Zazimalova
authors.forename: R M
authors.initials: RM
authors.lastname: Napier
mesh_terms: D001692:Biological Transport; D018507:Gene Expression Regulation, Developmental; D006706:Homeostasis; D007210:Indoleacetic Acids / Q000096:biosynthesis* / Q000378:metabolism; D063245:Plant Development; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D007210:Indoleacetic Acids