Examination of normalized pulse volume-blood volume relationship: toward a more valid estimation of the finger sympathetic tone.
The pulsatile ac component (DeltaI) superimposed on the transmitted dc components (I: tissue plus blood) are obtained from a near-infrared finger photoplethysmogram using a wavelength of 810 nm. Only the dc component is given in an ischaemic circulatory state (I(t): tissue only). Based on Lambert-Beer's law, normalized pulse volume (NPV; =DeltaI/I) and blood volume [BV; =ln(I(t)/I)] have recently been advocated as quantitative measures. In this study, the NPV-BV relationship was examined using the finger occlusion method during rest and mental arithmetic in 16 female undergraduates. Finger vascular tone during stress was evaluated by the distance of the linear and parallel NPV-BV regression lines (D(NB)) between rest and stress conditions. A reference standard was provided by the linear regression lines of compliance index (CI=NPV/pulse pressure) and BV to the transmural pressure. The estimates at 40 mmHg of transmural pressure, as an arbitrarily chosen reference point, were calculated (CI40 and BV40). D(NB) correlated well with them (r=0.81 and 0.94, respectively). The multiple regression with mean blood pressure indicated that the combination of D(NB) and the reactivities in heart period could explain approximately 50% of valiance in pressor response. In conclusion, D(NB) is easily obtainable from the NPV-BV function and seems to be more specific and valid than NPV as an index of finger sympathetic tone, since it adjusts the mechanical effect of arterial distending pressure.
Tanaka
Gohichi
G
Department of Psychology, School of Medicine, Sapporo Medical University, South 1 West 17, Chuo-ku, Sapporo 060-8556, Japan. gtanaka@sapmed.ac.jp
Sawada
Yukihiro
Y
D000328:Adult; D001794:Blood Pressure; D001810:Blood Volume; D005260:Female; D005385:Fingers / Q000098:blood supply* / Q000294:innervation*; D006339:Heart Rate; D006801:Humans; D008433:Mathematics; D017156:Photoplethysmography; D011674:Pulse; D012044:Regression Analysis; D012146:Rest; D013315:Stress, Psychological / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013997:Time Factors; D014666:Vasomotor System / Q000503:physiopathology