Nanoscale tripodal 1,3,5,7-tetrasubstituted adamantanes for AFM applications.
The synthesis of four novel nanoscale 1,3,5,7-tetrasubstituted adamantanes 22 and 25-27 designed for atomic force microscopy (AFM) applications is described. Each tetrahedrally shaped molecule incorporates a broad tripodal base made up of three identical legs that terminate with a sulfur-containing moiety, which is either a 4-acetylsulfanylmethylphenyl unit or else a (1,2,5-dithiazepan-1-yl)phenyl unit. The sulfur atoms are intended for eventual binding of the molecule multivalently to the apex of a gold-coated commercial AFM tip through formation of multiple S-Au bonds. In each molecule, the fourth terminus is a para-substituted benzoic acid methyl ester that is designed to scan the sample. We demonstrate that 27 is sufficiently large and rigid to be imaged by a conventional AFM tip. Adamantanes 22 and 25-27 may also find application as chemically well-defined nanoscale objects for calibration of AFM tips.
Li
Quan
Q
Department of Chemistry, University of Oregon, Eugene, OR 97403-1253, USA.
Rukavishnikov
Aleksey V
AV
Petukhov
Pavel A
PA
Zaikova
Tatiana O
TO
Jin
Changshu
C
Keana
John F W
JF
D000218:Adamantane / Q000031:analogs & derivatives* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018625:Microscopy, Atomic Force / Q000379:methods*; D015394:Molecular Structure; D036103:Nanotechnology
D000218:Adamantane