title: Release from transdermal delivery systems. Application of a new non isothermic method to Trans-Ver-Sal patches.
abstract: In this paper a new non isothermic method for the determination of the release drug rate constant (k) from a transdermal delivery system is proposed. The new method was applied to transdermal patches Trans-Ver-Sal. The results obtained prove to be able to release salicylic acid of transdermal system and the effectiveness of the new method propose.
authors.affiliation: Dipartimento di Chimica Inorganica, Chimica Analitica e Chimica Fisica, Università di Messina, Messina, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Alibrandi
authors.forename: S
authors.initials: S
authors.lastname: Coppolino
authors.forename: N
authors.initials: N
authors.lastname: Micali
authors.forename: A
authors.initials: A
authors.lastname: Villari
mesh_terms: D000279:Administration, Cutaneous; D000465:Algorithms; D002138:Calibration; D016503:Drug Delivery Systems; D020156:Salicylic Acid / Q000008:administration & dosage / Q000493:pharmacokinetics; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet
chemical_list: D020156:Salicylic Acid