title: Evaluation of antibacterial activity of Mangifera indica on anaerobic dental microglora based on in vivo studies.
abstract: The present study was carried out to compare the subgingival plaque microflora in mango leaf users. Fifty subjects of both sexes, 25 of them used tooth brush and 25 used mango leaf as their home care hygiene device were included in the study. The microbiological evaluation for specific bacterial counts of Actinobacillus actinomycetemcomitans, Prevotella intermedia, Porphyromonas gingivalis, Fusobacterium nucleatum and Peptostreptococcus micros were carried out for all subject. Specific microbial evaluation revealed significant decrease in the proportion of P. intermedia and P. gingivalis in mango leaf users compared to tooth brush users. It shows that mangiferin possesses antibacterial activity in vivo against specific periodontal pathogens such as P. intermedia and P. gingivalis. Use of mango leaf in conjunction with a tooth brush will be a good home care device for maintenance of oral hygiene.
authors.affiliation: Department of Microbiology, K M C, Manipal.
authors.forename: Indira
authors.initials: I
authors.lastname: Bairy
authors.forename: S
authors.initials: S
authors.lastname: Reeja
authors.lastname: Siddharth
authors.forename: P Suganghi
authors.initials: PS
authors.lastname: Rao
authors.forename: Mahalinga
authors.initials: M
authors.lastname: Bhat
authors.forename: P G
authors.initials: PG
authors.lastname: Shivananda
mesh_terms: D005069:Evaluation Studies as Topic; D005260:Female; D005888:Gingival Pocket / Q000382:microbiology; D006801:Humans; D008297:Male; D031022:Mangifera / Q000737:chemistry*; D009910:Oral Hygiene / Q000193:education*; D010510:Periodontal Diseases / Q000382:microbiology* / Q000517:prevention & control; D010512:Periodontal Index; D028321:Plant Preparations / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal; D016966:Porphyromonas gingivalis / Q000187:drug effects* / Q000302:isolation & purification; D018720:Prevotella / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D028321:Plant Preparations