title: [Surgical treatment of bilateral renal cell carcinoma].
abstract: The paper presents the results of surgical treatment of bilateral tumors of the kidneys. Bilateral neoplasms were detected in 28 of 1200 patients with renal cell carcinoma (2.3%). Synchronous tumors were found in 12 patients (42.8%), asynchronous--in 16 (57.2%). Operation on both the kidneys for tumor was carried out in 21 patients from 28 (75%). In both groups operations including enucleation of the tumors (60% in the group with synchronous cancer and 53.8%) in the group with asynchronous one) prevailed. All the patients were operated in two stages. Local relapses occurred in 6 of 21 patients (28.5%). A relapse after nephrectomy was observed in 2 patients (9.5%). Recurrent tumor in the remnant of the kidney after nephron-sparing surgery was observed in 4 patients (19%). General 5 year survival in patients with synchronous bilateral tumors was 38.5%, whereas 5-year cancer-specific survival reached 47.4%. For asynchronous cancer these parameters were 49.6 and 58.7%, respectively. It is emphasized that all patients with renal cancer after radical nephrectomy should be followed up and undergo annual check-up with US and/or CT lifelong to detect possible asynchronous tumor. Genetic studies are necessary to specify differentiation of the form of bilateral neoplasm.
authors.forename: A S
authors.initials: AS
authors.lastname: Pereverzev
authors.forename: D V
authors.initials: DV
authors.lastname: Shchukin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Iliukhin
authors.forename: V V
authors.initials: VV
authors.lastname: Megera
mesh_terms: D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012008:Recurrence