title: [Drug poisoning].
abstract: A review is made of acute poisoning by opiates and its treatment in the emergency services, bearing in mind the progressive decline in the number of cases presented with the arrival of new forms of their administration, as well as the presence of new addictive drugs that have resulted in a shift in consumption habits. Reference is also made to the way in which the different types of existing substances originated, with the aim of achieving a better understanding of their use and in order to administer the most suitable treatment when poisoning occurs. Cocaine poisoning is discussed, with reference to its clinical picture, diagnosis and treatment. The consumption of illegal drugs in our country has undergone a notable change in recent years, with heroin being relegated and the incorporation of cocaine, amphetamine derivatives such as "ecstasy" (MDMA), "liquid ecstasy" (GHB) and, to a lesser extent, ketamine. A review is made of cannabis and its derivates, from the history of its consumption and the preparations employed to the effects produced in the different bodily systems. A brief explanation is also given of its metabolites and its principal mechanisms of action. Finally, we comment on the effects of LSD and hallucinogenic mushrooms.
authors.affiliation: Servicio de Psiquiatría, Hospital de Navarra, 31008 Pamplona Spain.
authors.forename: I
authors.initials: I
authors.lastname: Gainza
authors.forename: S
authors.initials: S
authors.lastname: Nogué
authors.forename: C
authors.initials: C
authors.lastname: Martínez Velasco
authors.forename: R S
authors.initials: RS
authors.lastname: Hoffman
authors.forename: G
authors.initials: G
authors.lastname: Burillo-Putze
authors.forename: A
authors.initials: A
authors.lastname: Dueñas
authors.forename: J
authors.initials: J
authors.lastname: Gómez
authors.forename: M A
authors.initials: MA
authors.lastname: Pinillos
mesh_terms: D000208:Acute Disease; D006801:Humans; D009294:Narcotics / Q000506:poisoning*; D011041:Poisoning / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D009294:Narcotics