[Moebius syndrome due to the use of misoprostol. Case report].
We report a patient affected with Moebius Syndrome (OMIM 157900) due to the use of misoprostol during the first trimester of the pregnancy, when abortion was intended twice using this drug, vias vaginal (600 mg) and oral (900 mg), with failure to induce abortion on both occasions. Since the use of misoprostol for abortion, without any medical indication or supervision, appears to be rather frequent in our population and since there are reports of severe malformations in children born after failed intents of abortion with this medication, it is necessary to alert the medical community and the population in general about the teratogenic risks of this drug.
Sánchez
Otto
O
Centro de Microscopía Electrónica, Núcleo Bolívar, Universidad de Oriente, Apartado 83, Ciudad Bolívar, Venezuela 8001-A. osanche@telcel.net.ve
Guerra
Dania
D
D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects*; D000028:Abortion, Induced / Q000009:adverse effects; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D016595:Misoprostol / Q000009:adverse effects*; D020331:Mobius Syndrome / Q000139:chemically induced*; D011247:Pregnancy
D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol