Selective protein degradation by ligand-targeted enzymes: towards the creation of catalytic antagonists.
Davis
Benjamin G
BG
Dyson Perrins Laboratory Department of Chemistry, University of Oxford South Parks Road, Oxford, OX1 3QY, UK. Ben.Davis@chem.ox.ac.uk
Sala
Rafael F
RF
Hodgson
David R W
DR
Ullman
Astrid
A
Khumtaveeporn
Kanjai
K
Estell
David A
DA
Sanford
Karl
K
Bott
Richard R
RR
Jones
J Bryan
JB
D000426:Alcohol Dehydrogenase / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001360:Avidin / Q000737:chemistry / Q000378:metabolism; D001412:Bacillus subtilis / Q000201:enzymology; D001710:Biotin / Q000378:metabolism; D002384:Catalysis; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D006736:Horses; D008024:Ligands; D008099:Liver / Q000201:enzymology; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D013379:Substrate Specificity; D020860:Subtilisin / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D004791:Enzyme Inhibitors; D008024:Ligands; D001360:Avidin; D001710:Biotin; D000426:Alcohol Dehydrogenase; D020860:Subtilisin