title: Improved biotransformations on charged PEGA supports.
abstract: PEGA supports functionalised with permanent charges show superior swelling properties in aqueous media when compared to neutral PEGA; a novel positively charged PEGA resin significantly improves penicillin G amidase (PGA) catalysed biotransformation on solid support, by favouring accessibility of the negatively charged enzyme.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università degli Studi, Piazzale Europa 1, 34127, Trieste, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Basso
authors.forename: Luigi
authors.initials: L
authors.lastname: De Martin
authors.forename: Lucia
authors.initials: L
authors.lastname: Gardossi
authors.forename: Graham
authors.initials: G
authors.lastname: Margetts
authors.forename: Ian
authors.initials: I
authors.lastname: Brazendale
authors.forename: Annie Y
authors.initials: AY
authors.lastname: Bosma
authors.forename: Rein V
authors.initials: RV
authors.lastname: Ulijn
authors.forename: Sabine L
authors.initials: SL
authors.lastname: Flitsch
mesh_terms: D001711:Biotransformation; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: C109511:bis(polyoxyethylene bis(amine)); D011092:Polyethylene Glycols