title: Auditory neuropathy/dyssynchrony: its diagnosis and management.
abstract: Patients with auditory neuropathy/dyssynchrony exhibit no auditory brain stem response (ABR), no middle ear muscle response, and both normal otoacoustic emissions or normal cochlear microphonics. An absent or grossly abnormal ABR is not always associated with deafness. In contrast, a hearing loss of 30 dB or more usually predicts absent otoacoustic emissions, but normal emissions can be seen in some patients whose behavioral audiograms imply total deafness. This article reviews the underlying physiology that makes these tests both useful and potentially misleading, and recommends steps to be considered by primary care physicians and other professionals to compensate for the vulnerabilities of each of the procedures.
authors.affiliation: Kresge Hearing Research Laboratory, Dept. of Otolaryngology and Biocommunication, Louisiana State University Health Sciences Center, 533 Bolivar Street, Fifth Floor, New Orleans, LA 70112, USA. cberli@lsuhsc.edu
authors.forename: Charles I
authors.initials: CI
authors.lastname: Berlin
authors.forename: Thierry
authors.initials: T
authors.lastname: Morlet
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Hood
mesh_terms: D001301:Audiometry, Pure-Tone; D001304:Auditory Diseases, Central / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D002648:Child; D003051:Cochlea / Q000503:physiopathology; D019929:Cochlear Implantation; D003056:Cochlear Nerve / Q000503:physiopathology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D006310:Hearing Aids; D006801:Humans; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D010525:Peripheral Nerves / Q000503:physiopathology; D013997:Time Factors; D014706:Verbal Learning