title: Lewis acid-induced intramolecular Friedel-Crafts cyclization of 1,3-bis-exocyclic dienes. a new route to 4a-methyltetrahydrofluorenes.
abstract: [reaction: see text] An efficient new method for constructing the 4a-methyltetrahydrofluorene skeleton was achieved via Friedel-Crafts intramolecular cyclization of 1,3-bis-exocyclic dienes. This strategy offers a simple and promising method for accessing complex structures.
authors.affiliation: Laboratoire de Chimie Organique 1, associé au CNRS, Université Claude Bernard Lyon 1, CPE, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Lomberget
authors.forename: Emilie
authors.initials: E
authors.lastname: Bentz
authors.forename: Didier
authors.initials: D
authors.lastname: Bouyssi
authors.forename: Geneviève
authors.initials: G
authors.lastname: Balme
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation
chemical_list: D000466:Alkadienes; D001896:Boron Compounds; D005449:Fluorenes