Relapsing acute respiratory failure induced by minocycline.
The antibiotic minocycline, which is used in the treatment of acne, has been associated with various pulmonary complications such as pulmonary lupus and hypersensitivity pneumonitis. We now report a particularly severe case of minocycline-related pulmonary toxicity that was characterized by a relapsing form of hypersensitivity eosinophilic pneumonia complicated by acute respiratory failure.
Oddo
Mauro
M
Critical Care Division, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Liaudet
Lucas
L
Lepori
Mattia
M
Broccard
Alain F
AF
Schaller
Marie-Denise
MD
D000152:Acne Vulgaris / Q000188:drug therapy; D000208:Acute Disease; D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced; D012008:Recurrence; D012131:Respiratory Insufficiency / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D008911:Minocycline