[The inhibitory effect of saponins from Tribulus terrestris on Bcap-37 breast cancer cell line in vitro].
The inhibitory effect of saponins from Tribulus terrestris (STT) on Bcap37 breast cancer cell line were determined by cell growth curve, MTT assay, protein content assay and morphological observation. The results showed that STT had potent inhibitory effect on Bcap-37 cell line in a concentration-dependent manner. Bcap-37 cell exhibited morphological alteration, namely, cells got round and shrunk, nuclei contracted after treating with STT.
Sun
Bin
B
Life Science School of East China Normal University, Shanghai 200062.
Qu
Weijing
W
Bai
Zhongjiang
Z
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D018276:Carcinoma, Medullary / Q000378:metabolism / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology; D005260:Female; D006801:Humans; D009363:Neoplasm Proteins / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry*; D000091402:Prohibitins; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D032444:Tribulus / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D009363:Neoplasm Proteins; C000717331:PHB2 protein, human; D000091402:Prohibitins; D012503:Saponins