Psychosis and epilepsy: a neurologist's perspective.
Epilepsy and psychosis are diseases of the brain which cause considerable impact on quality of life particularly when they occur in the same individual. This review comments on postictal psychosis, chronic schizophrenia like psychosis in epilepsy, and the psychoses related to the treatment of epilepsy with antiepileptic drugs and surgery. Possible mechanisms of psychosis including the concept of forced normalization and dopaminergic overactivity in the mesolimbic system are discussed.
McLachlan
Richard S
RS
Neurology Division, Department of Medicine, Shaikh Khalifa Medical Center.
D000208:Acute Disease; D000328:Adult; D000818:Animals; D038481:Anterior Temporal Lobectomy / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D002908:Chronic Disease; D015897:Comorbidity; D004298:Dopamine / Q000502:physiology; D004827:Epilepsy / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008032:Limbic System / Q000503:physiopathology; D008297:Male; D009462:Neurology; D011618:Psychotic Disorders / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy
D000927:Anticonvulsants; D004298:Dopamine