title: An efficient and selective method for preparing glycosyl sulfoxides by oxidizing glycosyl sulfides with OXONE or t-BuOOH on SiO2.
abstract: Silica gel adsorbed with OXONE or t-BuOOH was used as a mild oxidant to selectively oxidize glycosyl sulfides to corresponding sulfoxides in good yields and without sulfones formation. This method was also found compatible with various other functional groups in the glycosides.
authors.affiliation: Institute of Chemistry, Academia Sinica, 128, Sec. 2, Yen-Chiu-Yuan Rd. Nankang, 115, Taipei, Taiwan, ROC.
authors.forename: Ming-Yi
authors.initials: MY
authors.lastname: Chen
authors.forename: Laxmikant Narhari
authors.initials: LN
authors.lastname: Patkar
authors.forename: Hui-Ting
authors.initials: HT
authors.lastname: Chen
authors.forename: Chun-Cheng
authors.initials: CC
authors.lastname: Lin
mesh_terms: D002384:Catalysis; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D010084:Oxidation-Reduction; D012822:Silicon Dioxide / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry*; D013454:Sulfoxides / Q000138:chemical synthesis* / Q000737:chemistry; D013464:Sulfuric Acids / Q000737:chemistry*; D013997:Time Factors; D020122:tert-Butylhydroperoxide / Q000737:chemistry*
chemical_list: D006027:Glycosides; D013440:Sulfides; D013454:Sulfoxides; D013464:Sulfuric Acids; D012822:Silicon Dioxide; D020122:tert-Butylhydroperoxide; C048813:potassium peroxymonosulfuric acid