title: Interpreting the results of the amplified Mycobacterium tuberculosis direct test for detection of M. tuberculosis rRNA.
abstract: The Amplified Mycobacterium tuberculosis Direct (AMTD) test detects M. tuberculosis rRNA. By using culture of M. tuberculosis as a gold standard, a number of different diagnostic indices were examined in an attempt to determine the diagnostic performance of the AMTD test and demonstrate how it might usefully be interpreted during the early management of disease.
authors.affiliation: Department of Microbiology, Royal Brompton and Harefield Hospitals NHS Trust, London, United Kingdom.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Middleton
authors.forename: Paul
authors.initials: P
authors.lastname: Cullinan
authors.forename: Robert
authors.initials: R
authors.lastname: Wilson
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Kerr
authors.forename: Maureen V
authors.initials: MV
authors.lastname: Chadwick
mesh_terms: D003627:Data Interpretation, Statistical; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D015347:RNA Probes; D012335:RNA, Ribosomal / Q000235:genetics*; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*
chemical_list: D015347:RNA Probes; D012335:RNA, Ribosomal