title: [Hyperplasia of adrenal rests in the testicle: a rare cause of male infertility].
abstract: We report the case of a 37-year-old man with infertility caused by bilateral testicular masses secondary to congenital adrenal hyperplasia (21-hydroxylase deficiency). Testicular biopsy was done and its was initially interpreted as Leydig cell tumor but after clinical information was histologically reclassified as tumor of the adrenogenital syndrome. The differential diagnosis with Leydig cell tumor is discussed and it must be established through the clinical, biochemical, radiological and pathological features.
authors.affiliation: Servicio de Anatomía Patológica, Centro Médico POVISA, Vigo, Pontevedra.
authors.forename: P
authors.initials: P
authors.lastname: san Miguel Fraile
authors.forename: G
authors.initials: G
authors.lastname: Fernández Fernández
authors.forename: F
authors.initials: F
authors.lastname: Meijide Rico
authors.forename: I
authors.initials: I
authors.lastname: Antón Badiola
authors.forename: J A
authors.initials: JA
authors.lastname: Ortiz-Rey
authors.forename: C
authors.initials: C
authors.lastname: Alvarez Alvarez
authors.forename: A
authors.initials: A
authors.lastname: de la Fuente Buceta
mesh_terms: D019326:17-alpha-Hydroxyprogesterone / Q000097:blood; D000311:Adrenal Glands; D000312:Adrenal Hyperplasia, Congenital / Q000097:blood / Q000150:complications*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D001706:Biopsy; D002828:Choristoma / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007248:Infertility, Male / Q000209:etiology*; D007984:Leydig Cell Tumor / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D013255:Steroid 21-Hydroxylase / Q000235:genetics / Q000378:metabolism; D013733:Testicular Diseases / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis; D014463:Ultrasonography
chemical_list: D019326:17-alpha-Hydroxyprogesterone; D000324:Adrenocorticotropic Hormone; D013255:Steroid 21-Hydroxylase; D006854:Hydrocortisone