Lipschütz genital ulceration: a rare manifestation of paratyphoid fever.
In 1913, a distinctive clinical entity of acute genital ulcer occurring in an adolescent girl with a non-venereal infectious aetiology was described by Lipschütz. Since the initial description, several aetiologies have been discussed, and among them, paratyphoid fever is very uncommon. After her return from a trip, a 25-year-old girl developed high fever and diarrhoea. Examination of the vulva revealed a genital ulcer. The rest of the general examination was normal. Blood cultures identified Salmonella paratyphi A, and a diagnosis of Lipschütz's ulcer associated with paratyphoid fever was made. Bacteriaemia was then treated with antibiotics and the vulvar ulceration rapidly disappeared. Lipschütz described a distinctive clinical entity of acute genital ulcers occurring in adolescents. To our knowledge, we report herein the second case associated with proved paratyphoid fever. The authors thus recommend that typhoid or paratyphoid fever should be included in the differential diagnosis of genital ulcerations.
Pelletier
Fabien
F
Service de Dermatologie 1, Hôpital Saint-Jacques, 2, place Saint-Jacques, 25030 Besançon cedex, France.
Aubin
François
F
Puzenat
Eve
E
Deprez
Philippe
P
Blanc
Dominique
D
Estavoyer
Jean-Marie
JM
Humbert
Philippe
P
D000328:Adult; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D010284:Paratyphoid Fever / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D012482:Salmonella paratyphi A / Q000302:isolation & purification; D014456:Ulcer / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014845:Vulvar Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology