title: Atypical thymic carcinoid and malignant somatostatinoma in type I multiple endocrine neoplasia syndrome: case report.
abstract: Thymic carcinoid and malignant somatostatinoma are both rare, and their concurrent presence in multiple endocrine neoplasia type 1 (MEN-1) has never been reported in the English literature to date. We present a patient with thymic carcinoid and malignant somatostatinoma in association with MEN-1. The patient eventually died of pulmonary aspergillosis and respiratory failure. Autopsy showed a 16 x 10 x 8-cm thymic carcinoid tumor, parathyroid and adrenal gland hyperplasia, and malignant somatostatinoma of the pancreas with a metastatic tumor over the splenic hilum.
authors.affiliation: Division of Thoracic Surgery, Taipei Veterans General Hospital, and School of Medicine, National Yang-Ming University, Taipei, ROC.
authors.forename: Frank Cheau-Feng
authors.initials: FC
authors.lastname: Lin
authors.forename: Chih-Ming
authors.initials: CM
authors.lastname: Lin
authors.forename: Chih-Cheng
authors.initials: CC
authors.lastname: Hsieh
authors.forename: Wing-Yin
authors.initials: WY
authors.lastname: Li
authors.forename: Liang-Shun
authors.initials: LS
authors.lastname: Wang
mesh_terms: D000311:Adrenal Glands / Q000473:pathology; D000328:Adult; D001344:Autopsy; D002276:Carcinoid Tumor / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D006965:Hyperplasia; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000473:pathology*; D010280:Parathyroid Glands / Q000473:pathology; D013005:Somatostatinoma / Q000473:pathology*; D013953:Thymus Neoplasms / Q000473:pathology*