title: Achieving evolvable Web-database bioscience applications using the EAV/CR framework: recent advances.
abstract: The EAV/CR framework, designed for database support of rapidly evolving scientific domains, utilizes metadata to facilitate schema maintenance and automatic generation of Web-enabled browsing interfaces to the data. EAV/CR is used in SenseLab, a neuroscience database that is part of the national Human Brain Project. This report describes various enhancements to the framework. These include (1) the ability to create "portals" that present different subsets of the schema to users with a particular research focus, (2) a generic XML-based protocol to assist data extraction and population of the database by external agents, (3) a limited form of ad hoc data query, and (4) semantic descriptors for interclass relationships and links to controlled vocabularies such as the UMLS.
authors.affiliation: Center for Medical Informatics, Yale University School of Medicine, PO Box 208009, New Haven, CT 06520-8009, USA. luis.marenco@yale.edu
authors.forename: Luis
authors.initials: L
authors.lastname: Marenco
authors.forename: Nicholas
authors.initials: N
authors.lastname: Tosches
authors.forename: Chiquito
authors.initials: C
authors.lastname: Crasto
authors.forename: Gordon
authors.initials: G
authors.lastname: Shepherd
authors.forename: Perry L
authors.initials: PL
authors.lastname: Miller
authors.forename: Prakash M
authors.initials: PM
authors.lastname: Nadkarni
mesh_terms: D003628:Database Management Systems; D019992:Databases as Topic / Q000458:organization & administration*; D020407:Internet; D011381:Programming Languages; D012660:Semantics; D012984:Software; D018875:Vocabulary, Controlled