title: Using soluble polymers in latent biphasic systems.
abstract: A new strategy for carrying out reactions with a soluble polymer-bound reagent or catalyst is described. In this latent biphasic process, a solvent mixture at the cusp of immiscibility is prepared and used to carry out a reaction under homogeneous conditions. Then, after the reaction is complete, this mixture is perturbed by the addition of solvent or some other perturbing agent to produce a biphasic mixture. The product-containing phase is then separated under liquid/liquid conditions from the polymer-containing phase. The generality of this process is demonstrated using both dye-labeled polymers as surrogates for polymer-bound catalysts and with various polymer-bound organic and transition metal catalysts or reagents. In cases where a polymeric catalyst is used, the addition of fresh solvent and substrate reforms the original mixture allowing facile reuse of the catalyst.
authors.affiliation: Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station 77842-3012, USA. bergbreiter@tamu.edu
authors.forename: David E
authors.initials: DE
authors.lastname: Bergbreiter
authors.forename: Philip L
authors.initials: PL
authors.lastname: Osburn
authors.forename: Thomas
authors.initials: T
authors.lastname: Smith
authors.forename: Chunmei
authors.initials: C
authors.lastname: Li
authors.forename: Jonathon D
authors.initials: JD
authors.lastname: Frels