title: Eye findings of diffuse unilateral subacute neuroretinitis and multiple choroidal infiltrates associated with neural larva migrans due to Bbaylisascaris procyonis.
abstract: OBJECTIVE
  To report childhood infection with Baylisascaris procyonis (raccoon round worm) manifesting as diffuse unilateral subacute neuroretinitis (DUSN) and choroidal infiltrates in association with neurologic disease (neural larva migrans).
  
  
  METHODS
  Observational case series, one with eye manifestations of DUSN, the other with choroidal infiltrates, both with severe neurologic degeneration.
  
  
  RESULTS
  Indirect immunofluorescence assays on serum and cerebrospinal fluid were positive for B. procyonis in one and serially positive and increasing in the other. Both children had a history of pica and raccoon exposure.
  
  
  CONCLUSIONS
  Baylisascaris procyonis infection is associated with two cases of severe neurologic degeneration with ocular lesions: DUSN and choroidal infiltrates. Although B. procyonis is known to cause DUSN, these cases indicate that concomitant ocular migration may accompany neural larva migrans. These are the third and forth cases in the US literature of neural larva migrans due to B. procyonis with eye findings.
authors.affiliation: Division of Ophthalmology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA. mbmets@nwu.edu
authors.forename: Marilyn Baird
authors.initials: MB
authors.lastname: Mets
authors.forename: A Gwendolyn
authors.initials: AG
authors.lastname: Noble
authors.forename: Surendra
authors.initials: S
authors.lastname: Basti
authors.forename: Patrick
authors.initials: P
authors.lastname: Gavin
authors.forename: A Todd
authors.initials: AT
authors.lastname: Davis
authors.forename: Stanford T
authors.initials: ST
authors.lastname: Shulman
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Kazacos
mesh_terms: D000208:Acute Disease; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood / Q000134:cerebrospinal fluid; D000947:Antigens, Helminth / Q000276:immunology; D017191:Ascaridida Infections / Q000469:parasitology*; D001199:Ascaridoidea / Q000276:immunology / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D015862:Choroid Diseases / Q000469:parasitology*; D015822:Eye Infections, Parasitic / Q000469:parasitology*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007815:Larva Migrans / Q000469:parasitology*; D008297:Male; D012173:Retinitis / Q000469:parasitology*
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth