title: Acupuncture for alcohol withdrawal: a randomized controlled trial.
abstract: OBJECTIVE
  Previous trials on acupuncture in alcohol addiction were in outpatients and focused on relapse prevention. Rates of dropout were high and interpretation of results difficult. We compared auricular laser and needle acupuncture with sham laser stimulation in reducing the duration of alcohol withdrawal.
  
  
  METHODS
  Inpatients undergoing alcohol withdrawal were randomly allocated to laser acupuncture (n = 17), needle acupuncture (n = 15) or sham laser stimulation (n = 16). Attempts were made to blind patients, therapists and outcome assessors, but this was not feasible for needle acupuncture. The duration of withdrawal symptoms (as assessed using a nurse-rated scale) was the primary outcome; the duration of sedative prescription was the secondary outcome.
  
  
  RESULTS
  Patients randomized to laser and sham laser had identical withdrawal symptom durations (median 4 days). Patients randomized to needle stimulation had a shorter duration of withdrawal symptoms (median 3 days; P = 0.019 versus sham intervention), and tended to have a shorter duration of sedative use, but these differences diminished after adjustment for baseline differences.
  
  
  CONCLUSIONS
  The data from this pilot trial do not suggest a relevant benefit of auricular laser acupuncture for alcohol withdrawal. A larger trial including adequate sham interventions is needed, however, to reliably determine the effectiveness of any type of auricular acupuncture in this condition.
authors.affiliation: Psychiatric Hospital Münsingen, 3110 Münsingen, Switzerland.
authors.forename: François
authors.initials: F
authors.lastname: Trümpler
authors.forename: Suzan
authors.initials: S
authors.lastname: Oez
authors.forename: Peter
authors.initials: P
authors.lastname: Stähli
authors.forename: Hans Dieter
authors.initials: HD
authors.lastname: Brenner
authors.forename: Peter
authors.initials: P
authors.lastname: Jüni
mesh_terms: D015670:Acupuncture Therapy / Q000295:instrumentation / Q000379:methods*; D000328:Adult; D000437:Alcoholism / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016016:Proportional Hazards Models; D018709:Statistics, Nonparametric; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*