[Intraoperative radiotherapy for 30 esophageal carcinoma patients].
OBJECTIVE
To analyze the complications and treatment results of intraoperative radiotherapy (IORT) for esophageal carcinoma.


METHODS
Sixty patients with thoracic esophageal carcinoma underwent esophagectomy through right thoractomy, 30 patients of whom received IORT of 15 - 25 Gy.


RESULTS
In patients who underwent IORT, 2 cases of pneumonitis, 1 case of anastomotic leak and 1 case of incisional wound infection were found. In patients underwent surgery only, 1 case of thoracic empyema and 1 case of anastomotic leak were found. All the complications ultimately healed. There was no operative mortality. During the follow-up of 3 years, in patients who underwent IORT, 2 of 3 died of radiation pneumonitis 24 and 26 months after IORT with one complicated with bronchoesophageal fistula. One of 3 died of multiple lung metastases. The 3-year survival rate was 88.0% (22/25) in IORT group and 76.0% (19/25) in surgery only group.


CONCLUSIONS
Intraoperative radiotherapy can reduce locoregional recurrence if performed to thoracic esophageal carcinoma patients without surgical contraindication or distant metastasis. Radiation pneumonitis, a common complication difficult to manage, implies a poor prognosis and, consequently, the lung and bronchus should be protected from the radiation.
Yan
Fu-lai
FL
Departments of Abdominal and Thoracic Surgical Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China.
Zhou
Xing-ming
XM
Chen
Qi-xun
QX
Jiang
Rong-xuan
RX
Fang
Jun
J
Lian
Yan-hong
YH
Zheng
Xiao
X
Chen
Xiu-yong
XY
Zhu
Yuan
Y
Di
Xiao-yun
XY
Wang
Jian
J
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage