Marrow stem cell potential within a continuum.
On the basis of our studies of the fluctuation of the hematopoietic stem cell phenotype with cell cycle trnsit, we hypothesize that the ability of marrow stem cells to convert to nonhematopoietic cells will also vary at different points in the cell cycle. The new biology of stem cells has an impact on many fields including developmental biology and stem cell biology and the clinical potential is enormous.
Quesenberry
P
P
The Research Department, Roger Williams Medical Center, Providence, Rhode Island 02908, USA. pquesenberry@rwmc.org
Colvin
G
G
Lambert
J F
JF
Abedi
M
M
Cerny
J
J
Dooner
M
M
Moore
B
B
McAuliffe
C
C
Demers
D
D
Greer
D
D
Parent
A
A
Badiavas
E
E
Lum
L
L
Falanga
V
V
D000818:Animals; D002453:Cell Cycle; D002454:Cell Differentiation; D048429:Cell Size; D016207:Cytokines / Q000494:pharmacology; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects; D051379:Mice; D013997:Time Factors
D016207:Cytokines