title: Capillary electrophoretic behaviors of pharmacologically active xanthones from Securidaca inappendiculata with beta-cyclodextrin as a buffer additive.
abstract: The capillary electrophoretic (CE) behaviors of ten xanthones in the presence of beta-cyclodextrin (CD) are investigated, and apparent analyte-selector binding constants between beta-CD and the xanthones in the CE running buffer are calculated to elucidate the migration order. Also, the separation selectivity with beta-CD additive is compared with that of sulfated beta-CD additive. It is indicated that beta-CD can greatly change the separation selectivity of xanthones, and the electrophoretic behaviors of xanthones are rather different when using beta-CD from that when using sulfated beta-CD as an additive.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, P.R. China.
authors.forename: Tao
authors.initials: T
authors.lastname: Bo
authors.forename: Yongfa
authors.initials: Y
authors.lastname: Huang
authors.forename: Xuedong
authors.initials: X
authors.lastname: Yang
authors.forename: Ke An
authors.initials: KA
authors.lastname: Li
authors.forename: Huwei
authors.initials: H
authors.lastname: Liu
authors.forename: Lizhen
authors.initials: L
authors.lastname: Xu
mesh_terms: D002021:Buffers; D003505:Cyclodextrins / Q000737:chemistry*; D019075:Electrophoresis, Capillary / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D029608:Polygalaceae / Q000737:chemistry*; D014966:Xanthenes / Q000737:chemistry*; D044004:Xanthones; D047392:beta-Cyclodextrins
chemical_list: D002021:Buffers; D003505:Cyclodextrins; D014966:Xanthenes; D044004:Xanthones; D047392:beta-Cyclodextrins; C009689:xanthone; C031215:betadex