[Kikuchi's histiocytic necrotizing lymphadenitis].
Necrotizing histiocytic lymphadenitis (NHL) or Kikuchi-Fujimoto disease is an infrequent seen clinicopathologic entity that affects most frequently young women and individuals of eastern races, and that is characterized by fever and adenopathies (basically cervical) and systemic disease even though occasional patients present extranodal disease. We present two young women with NHL and cutaneous affectation, and with lymphocytic meningitis in one of the patients. We discuss the etiology of NHL, the relation of NHL with collagen-vascular diseases (basically systemic erythematous lupus) the problem of the pathologic diagnosis, and the therapeutic possibilities in these patients.
Eroles Vega
G
G
Servicio de Medicina Interna. Hospital Severo Ochoa. Leganés. Madrid. Spain. aragonz@eresmas.com
Vicente Martín
C
C
Jusdado Ruiz-Capillas
J J
JJ
Guijarro Rojas
M
M
Lacambra Calvet
C
C
Burgos Lázaro
F
F
Solís Villa
J
J
D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology*; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D009000:Monocytes / Q000473:pathology; D009333:Neck
D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal