title: Fatal Lucio's phenomenon in 2 patients with previously undiagnosed leprosy.
abstract: We report 2 cases of Lucio's phenomenon, a rare, aggressive, occasionally fatal type 2 reaction occurring in the diffuse nonnodular type of lepromatous leprosy. The clinical diagnosis of Lucio's phenomenon is difficult, and there are no known predictive or prognostic factors. Despite institution of aggressive treatment after diagnosis, our 2 cases had fatal outcomes.
authors.affiliation: National Skin Centre, Singapore.
authors.forename: Por
authors.initials: P
authors.lastname: Ang
authors.forename: Yong-Kwang
authors.initials: YK
authors.lastname: Tay
authors.forename: See-Ket
authors.initials: SK
authors.lastname: Ng
authors.forename: Chew-Swee
authors.initials: CS
authors.lastname: Seow
mesh_terms: D000368:Aged; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007871:Leg Ulcer / Q000473:pathology*; D015440:Leprosy, Lepromatous / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012867:Skin / Q000473:pathology*