title: Neuroprotection for ischemic stroke.
abstract: Many pharmacological and nonpharmacologic neuroprotective therapies are in various phases of animal or human testing. The future in acute ischemic stroke therapy most likely will consist of combination therapies (Bonnono et al., 2000; Schellinger et al., 2001). An IV thrombolytic agent may be combined with an IA agent and then followed up with a neuroprotective strategy early in treatment of acute ischemic stroke. A hemicraniectomy may be combined with hypothermia to improve outcome (Georgiadis et al., 2002). Many resources (Fig 2) are available to assist neuroscience nurses in keeping abreast of this fast-paced area of development.
authors.affiliation: Villanova University College of Nursing, Villanova, PA, USA. Janice.Hinkle@Villanova.edu
authors.forename: Janice L
authors.initials: JL
authors.lastname: Hinkle
authors.forename: Lisa
authors.initials: L
authors.lastname: Bowman
mesh_terms: D002545:Brain Ischemia / Q000188:drug therapy*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D004509:Education, Nursing, Continuing; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D016166:Free Radical Scavengers / Q000627:therapeutic use*; D018755:GABA Agonists / Q000627:therapeutic use*; D006801:Humans; D020521:Stroke / Q000188:drug therapy*
chemical_list: D002121:Calcium Channel Blockers; D005343:Fibrinolytic Agents; D016166:Free Radical Scavengers; D018755:GABA Agonists