title: [Montenegro intradermoreaction after the test sequential repetitions in Porteirinha, Minas Gerais State, Brazil].
abstract: With the purpose of evaluating the response of sequential applications of Montenegro intradermoreaction (IDRM), we have repeated four times the test in the inhabitants of an endemic area for kala-azar, that resulted negative 3-4 years ago. Firstly, we have repeated three IDRM in those who remained negative, with a 60-day interval among them. In the second stage, we have performed a last reaction in all participants of the study. From the total of 49 individuals with prior negative IDRM, 19 (38.8%) have positivated the test in some of the times, 17 (34.7%) have given up the study and 13 (26.5%) remained with a negative result in all the applications. In the second stage, the repetition of IDRM has shown that from the 14 positive in some of the tests, 8 remained like this and 6 have become negative. Our results confirm the possibility of late hypersensitivity induction in some individuals as a consequence of IDRM application.
authors.affiliation: Departamento de Doenças Infecciosas e Parasitárias, Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG, Brasil.
authors.forename: Verênica Carneiro
authors.initials: VC
authors.lastname: Borges
authors.forename: Miguel César Merino
authors.initials: MC
authors.lastname: Ruiz
authors.forename: Patrícia Moreira
authors.initials: PM
authors.lastname: Gomes
authors.forename: André Ratto
authors.initials: AR
authors.lastname: Colombo
authors.forename: Luciana de Almeida
authors.initials: Lde A
authors.lastname: Silva
authors.forename: Héctor Dardo
authors.initials: HD
authors.lastname: Romero
authors.forename: Aluízio
authors.initials: A
authors.lastname: Prata
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007428:Intradermal Tests / Q000592:standards*; D007891:Leishmania / Q000276:immunology*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology
chemical_list: D000953:Antigens, Protozoan