Corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis.
OBJECTIVE
To report a case of corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis.


METHODS
Interventional case report.


METHODS
A 38-year-old homosexual male who presented with a unilateral uveitis secondary to syphilis developed large placoid macular lesions after treatment with oral prednisone that resolved when the corticosteroids were discontinued.


RESULTS
A cause-and-effect relationship was demonstrated between oral prednisone and the appearance of acute syphilitic posterior placoid chorioretinitis.


CONCLUSIONS
The clinical appearance of posterior placoid chorioretinitis in syphilis may be modulated by the immune status of the patient.
Zamani
Maryam
M
Department of Ophthalmology, George Washington University Hospital, (M.Z.), Washington, DC, USA.
Garfinkel
Richard A
RA
D000208:Acute Disease; D000284:Administration, Oral; D000328:Adult; D002825:Chorioretinitis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D015818:Eye Infections, Bacterial / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011241:Prednisone / Q000009:adverse effects*; D013587:Syphilis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D013588:Syphilis Serodiagnosis
D005938:Glucocorticoids; D011241:Prednisone