[Newborn hydronephrosis: dynamic renal scintigraphy with Tc99m MAG3 in the first month of life].
BACKGROUND
The early and accurate diagnosis of obstructive uropathy in the newborn, prevents secondary complications and kidney damage.


OBJECTIVE
To study the usefulness of Tc99M MAG3 diuretic renogram in newborns with hydronephrosis.


METHODS
Forty newborns, aged 1 to 30 days, with hydronephrosis, were studied. A Tc99M MAG3 diuretic renogram (DR) was done and its results were compared with clinical features and other imaging studies. Each kidney and its ureter, were considered a renal unit.


RESULTS
Seventy six renal units were evaluated. Twenty six were normal on prenatal ultrasound examination and DR. In 11 of the 50 renal units with hydronephrosis, renal function was impaired. Thus, it was impossible to obtain an excretory curve. In 17 of the 39 remaining renal units, the absence of obstructive uropathy was demonstrated clinically. In 16 of these, the DR showed absence of obstruction. In 20 of 21 renal units with confirmed obstructive uropathy, DR showed an obstructive pattern.


CONCLUSIONS
In newborns, there is an adequate Tc99M MAG3 uptake and diuretic response. Thus, DR becomes a good functional assessment method in newborns with hydronephrosis.
Orellana
Pilar
P
Departamentos de Radiología, Pediatría, Urología, Laboratorio de Medicina Nuclear, Hospital Clínico, Facultad de Medicina, Pontificia Universidad Católica de Chile. pilar@med.puc.cl
Baquedano
Paulina
P
Cavagnaro
Felipe
F
Lagomarsino
Edda
E
García
Cristián
C
Carreño
Juan Eduardo
JE
Meneses
Luis
L
D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging* / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D011446:Prospective Studies; D011866:Radioisotope Renography; D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide; D014517:Ureteral Obstruction / Q000150:complications / Q000000981:diagnostic imaging*
D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide