Antibiotic-loaded bone cement in orthopedic surgery.
Acrylic cement is used to secure implants to bone. When mixed with antibiotics or anticancer agents, acrylic cement slowly releases these agents while retaining its mechanical properties, thus providing specific in situ treatment.
Passuti
Norbert
N
Clinique Chirurgicale Orthopédique, CHU, Hôtel Dieu, 44093 cedex 1, Nantes, France. norbert.passuti@chu.nantes.fr
Gouin
François
F
D000180:Acrylic Resins / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000737:chemistry; D001843:Bone Cements / Q000737:chemistry; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D009985:Orthopedics / Q000379:methods*; D019736:Prostheses and Implants
D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D001843:Bone Cements; D003692:Delayed-Action Preparations; D004337:Drug Carriers