Comparison of carbohydrate moieties of sparganum proteins of the snake, mouse and those of adult worm.
The carbohydrate moieties of larval sparganum proteins in two different species, the snakes, Elaphe rufodorsata, the Balb/c mouse and those of the adult worm, Spirometra erinacei, were compared using five different lectins including GNA, SNA, MAA, PNA and DSA. The GNA positive 53 kDa molecule, which is excretory-secretory protease in the sparganum from the snake showed a stage specific and developmental regulation. We also suggested that sparganum glycosylation may be involved in immune evasion and differentiation into an adult worm.
Yang
Hyun Jong
HJ
Department of Parasitology, College of Medicine, Ewha Womans University, Seoul, 158-710, Korea. parayang@ewha.ac.kr
D000818:Animals; D050260:Carbohydrate Metabolism; D006023:Glycoproteins / Q000378:metabolism*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D012911:Snakes / Q000378:metabolism*; D013032:Sparganum / Q000378:metabolism*; D013045:Species Specificity; D013146:Spirometra / Q000378:metabolism*
D006023:Glycoproteins