title: Glycosides of Atractylodes lancea.
abstract: Five sesquiterpenoid glycosides (two guaiane-type glycosides and three eudesmane-type glucosides) and a glucoside of an acetylene derivative were newly isolated from the water-soluble portion of the methanolic extract of Atractylodes lancea rhizome together with 26 known compounds. Their structures were characterized as atractyloside A 14-O-beta-D-fructofuranoside, (1S,4S,5S,7R,10S)-10,11,14-trihydroxyguai-3-one 11-O-beta-D-glucopyranoside, (5R,7R,10S)-isopterocarpolone beta-D-glucopyranoside, cis-atractyloside I, (2R,3R,5R,7R,10S)-atractyloside G 2-O-beta-D-glucopyranoside, and (2E,8E)-2,8-decadiene-4,6-diyne-1,10-diol 1-O-beta-D-glucopyranoside on the basis of chemical and spectroscopic investigation. The presence of six characteristic guaiane-type glucosides in both rhizomes of A. lancea and Atractylodes japonica suggested a close chemotaxonomic relationship between them.
authors.affiliation: Showa Pharmaceutical University, Tokyo, Japan. Kitajima@ac.shoyaku.ac.jp
authors.forename: Junichi
authors.initials: J
authors.lastname: Kitajima
authors.forename: Akane
authors.initials: A
authors.lastname: Kamoshita
authors.forename: Toru
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Akihito
authors.initials: A
authors.lastname: Takano
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Fukuda
authors.forename: Susumu
authors.initials: S
authors.lastname: Isoda
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Ida
mesh_terms: D031174:Atractylodes / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*; D045789:Sesquiterpenes, Guaiane / Q000737:chemistry / Q000302:isolation & purification*; D012995:Solubility
chemical_list: D006027:Glycosides; D010936:Plant Extracts; D045787:Sesquiterpenes, Eudesmane; D045789:Sesquiterpenes, Guaiane