title: Nationwide surveillance for Staphylococcus aureus with reduced susceptibility to vancomycin in Korea.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) accounts for more than 70% of S. aureus isolates from tertiary hospitals in Korea. Clinical isolates of S. aureus were collected from eight provincial, university-affiliated hospitals during the period from June 1999 to January 2001 for nationwide surveillance. All isolates were screened for reduced susceptibility to vancomycin by using brain heart infusion agar containing 4 micro g of vancomycin per milliliter. Population analysis and the determination of the MIC of vancomycin were done for the isolates which grew on the screening agar plates. Of 682 total isolates, MRSA accounted for 64% (439 of 682). Of 27 (4%) isolates that grew on the screening agar plates, none showed the heteroresistance phenotype. No strains with reduced susceptibility to vancomycin were identified.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Republic of Korea.
authors.forename: Hong Bin
authors.initials: HB
authors.lastname: Kim
authors.forename: Wan Beom
authors.initials: WB
authors.lastname: Park
authors.forename: Ki Deok
authors.initials: KD
authors.lastname: Lee
authors.forename: Young Joo
authors.initials: YJ
authors.lastname: Choi
authors.forename: Sang Won
authors.initials: SW
authors.lastname: Park
authors.forename: Myoung-Don
authors.initials: MD
authors.lastname: Oh
authors.forename: Eui-Chong
authors.initials: EC
authors.lastname: Kim
authors.forename: Kang Won
authors.initials: KW
authors.lastname: Choe
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006785:Hospitals, University; D006801:Humans; D007723:Korea; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin