Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.
Sakiyama
Shigeru
S
Chiba Cancer Center Research Institute, 666-2 Nitona, Chuoh-ku, Chiba 260-8717, Japan.
Yu
Ling
L
Tomizawa
Minoru
M
Shimada
Hideaki
H
Kadomatsu
Kenji
K
Muramatsu
Takashi
T
Ikematsu
Shinya
S
Nakagawara
Akira
A
Tagawa
Masatoshi
M
D000256:Adenoviridae / Q000235:genetics; D000818:Animals; D015152:Blotting, Northern; D002352:Carrier Proteins / Q000235:genetics*; D002460:Cell Line; D045744:Cell Line, Tumor; D016207:Cytokines; D004305:Dose-Response Relationship, Drug; D004797:Enzyme-Linked Immunosorbent Assay; D015774:Ganciclovir / Q000494:pharmacology; D006801:Humans; D008156:Luciferases / Q000378:metabolism; D051379:Mice; D000078792:Midkine; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000235:genetics*; D011401:Promoter Regions, Genetic; D012333:RNA, Messenger / Q000378:metabolism; D013997:Time Factors; D015533:Transcriptional Activation
D002352:Carrier Proteins; D016207:Cytokines; D012333:RNA, Messenger; D000078792:Midkine; D008156:Luciferases; D015774:Ganciclovir