title: Central poorly differentiated adenocarcinoma of the maxilla: report of a case.
abstract: Central adenocarcinoma of the jaws is an extremely rare malignant tumor. We reported a case of poorly differentiated adenocarcinoma occurring intraosseously in the maxilla. A 62-year-old male was referred to our hospital because of swelling of the palate. MRI showed a central tumorous lesion in the maxilla. He underwent maxillectomy combined with neck and parapharyngeal dissection. Histologic examinations of the surgical specimen revealed poorly differentiated adenocaricinoma showing a positive reaction for PAS, CEA and cytokeratin. He underwent adjuvant chemotherapy with cis-platinum diamminodichloride, 5-fluorouracil, and pirarubicin, but he died of multiple distant metastases 7 months after the surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine. ume@med.kobe-u.ac.jp
authors.forename: Masahiro
authors.initials: M
authors.lastname: Umeda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yokoo
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Shibuya
authors.forename: Takahide
authors.initials: T
authors.lastname: Komori
authors.forename: Chiho
authors.initials: C
authors.lastname: Obayashi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy*; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology* / Q000628:therapy*; D008875:Middle Aged; D018570:Risk Assessment; D013514:Surgical Procedures, Operative / Q000379:methods