Sample preparation and liquid chromatography mass spectrometry analysis of alkylphenolic compounds and steroid sex hormones in sediments.
A new methodology, based on the use of accelerated solvent extraction (ASE) and highly selective cleanup using restricted access material (RAM) on-line coupled with liquid chromatography-mass spectrometry (LC-MS), is presented for the simultaneous and unequivocal determination of alkylphenol ethoxylates (APEOs), their degradation products and halogenated derivatives, and steroid sex hormones in sediment samples. Using the integrated RAM-LC-MS system, the simultaneous determination of alkylphenolic compounds and sex hormones was achieved, yielding recoveries higher than 60% and producing low MS background noise.
Petrović
Mira
M
Department of Environmental Chemistry, IIQAB-CSIC, Jordi Girona 18-26, Barcelona, Spain. mpeqam@cid.csic.es
Barceló
Damià
D
D000475:Alkenes / Q000737:chemistry*; D002853:Chromatography, Liquid / Q000379:methods*; D004784:Environmental Monitoring / Q000379:methods; D005027:Ethylene Oxide / Q000737:chemistry; D019015:Geologic Sediments / Q000032:analysis*; D012739:Gonadal Steroid Hormones / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods*; D010636:Phenols / Q000737:chemistry*
D000475:Alkenes; D012739:Gonadal Steroid Hormones; D010636:Phenols; D005027:Ethylene Oxide