Molecular evolution and recombination in gender-associated mitochondrial DNAs of the Manila clam Tapes philippinarum.
Doubly uniparental inheritance (DUI) provides an intriguing system for addressing aspects of molecular evolution and intermolecular recombination of mitochondrial DNA. For this reason, a large sequence analysis has been performed on Tapes philippinarum (Bivalvia, Veneridae), which has mitochondrial DNA heteroplasmy that is consistent with a DUI. The sequences of a 9.2-kb region (containing 29 genes) from 9 individuals and the sequences of a single gene from another 44 individuals are analyzed. Comparisons suggest that the two sex-related mitochondrial genomes do not experience a neutral pattern of divergence and that selection may act with varying strength on different genes. This pattern of evolution may be related to the long, separate history of M and F genomes within their tissue-specific "arenas." Moreover, our data suggest that recombinants, although occurring in soma, may seldom be transmitted to progeny in T. philippinarum.
Passamonti
Marco
M
Dipartimento di Biologia Evoluzionistica Sperimentale, Università degli Studi di Bologna, Italy. mpassa@alma.unibo.it
Boore
Jeffrey L
JL
Scali
Valerio
V
D000818:Animals; D001483:Base Sequence; D049872:Bivalvia; D004272:DNA, Mitochondrial; D019143:Evolution, Molecular; D005111:Extrachromosomal Inheritance; D005260:Female; D014644:Genetic Variation; D016678:Genome; D008297:Male; D008957:Models, Genetic; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012335:RNA, Ribosomal / Q000235:genetics / Q000378:metabolism; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D012737:Sex Factors
D004272:DNA, Mitochondrial; D012335:RNA, Ribosomal