title: Radical prostatectomy for locally advanced primary or recurrent rectal cancer.
abstract: OBJECTIVE
  Three papers including five patients have described en bloc radical prostatectomy for locally advanced rectal cancer.
  
  
  METHODS
  Six patients (median age 63 years) underwent en bloc radical prostatectomy for locally advanced (3) or recurrent (3) rectal cancer involving the prostate. Quality of life questionnaires were answered postoperatively and the data prospectively entered in a database.
  
  
  RESULTS
  One primary case had low anterior resection (LAR), the others abdominoperineal resections (APR) of R0 stage. Two recurrent cases had APRs and one tumour resection-all R1 stage. Anastomotic leakage led to construction of an ileal conduit in one patient and in two healed on conservative treatment. Follow up was 10-50 months. One patient died from distant metastases at 29 months postoperatively, one was operated for a single lung metastasis and one has disseminated lung metastases. None has developed local recurrence. Four of the five with anastomoses had good quality of life and none wanted an ileal conduit.
  
  
  CONCLUSIONS
  In spite of a relatively high urinary leak rate the total complication rate seems to be lower than after pelvic exenteration. En bloc radical prostatectomy seems an option in selected patients otherwise needing pelvic exenteration for locally advanced or recurrent rectal cancer.
authors.affiliation: Department of Surgical Oncology, The Norwegian Radium Hospital, Oslo, Norway. johann.wiig@c2i.net
authors.forename: J N
authors.initials: JN
authors.lastname: Wiig
authors.forename: H
authors.initials: H
authors.lastname: Waehre
authors.forename: S G
authors.initials: SG
authors.lastname: Larsen
authors.forename: M
authors.initials: M
authors.lastname: Braendengen
authors.forename: K-E
authors.initials: KE
authors.lastname: Giercksky
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome