Endocrine paraneoplastic syndromes in lung cancer.
Lung tumors are capable of synthesizing and secreting peptide proteins (hormones) that lead to a variety of endocrine paraneoplastic syndromes. Knowledge about the clinical manifestations, pathophysiology, and treatment of these syndromes has evolved over time. This article provides an up-to-date overview of this knowledge.
Mazzone
Peter J
PJ
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA. mazzonp@ccf.org
Arroliga
Alejandro C
AC
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism*; D014667:Vasopressins / Q000378:metabolism*
D014408:Biomarkers, Tumor; D044162:Parathyroid Hormone-Related Protein; D014667:Vasopressins; D000324:Adrenocorticotropic Hormone