[Coinfection with hepatitis C and B viruses with pre-C mutant].
We report on a case of co-infection VHB-VHC with a pre-core mutant, a rare association in the literature. The last consensus conference in march 2002 did not help us so much, since only VHC-VIH co-infection was considered. We report on our therapeutic experience about the treatment and discuss the recent studies aimed to define the function of respective virus in the case of co-infection. In the present case, the VHC infection has been completely cured, but some problems with the VHB infection are still unsolved.
Lepilleur
B
B
Laboratoire, 3, CHG Saint Dizier, Centre hospitalier, Rue Godard Jeanson, 52115 Saint Dizier cedex.
Schoeny
M
M
Melin
P
P
D000998:Antiviral Agents / Q000627:therapeutic use; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D005260:Female; D016174:Hepacivirus / Q000235:genetics*; D006509:Hepatitis B / Q000150:complications* / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics*; D006526:Hepatitis C / Q000150:complications* / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008875:Middle Aged; D009154:Mutation / Q000235:genetics*; D016133:Polymerase Chain Reaction; D012254:Ribavirin / Q000627:therapeutic use; D019562:Viral Load
D000998:Antiviral Agents; D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies; D012254:Ribavirin; D007372:Interferons