title: Piperacillin induced bone marrow suppression: a case report.
abstract: BACKGROUND
  Piperacillin (and piperacillin/tazobactam) is a commonly prescribed antibiotic and is generally considered safe. We report a case of piperacillin induced bone marrow suppression.
  
  
  METHODS
  A 19-year-old boy was being treated with piperacillin followed by piperacillin/tazobactam for infected pancreatic pseudocyst. After 21 days of treatment, he developed neutropenia and thrombocytopenia. These reversed promptly after stopping piperacillin/tazobactam. The time course of events suggested that piperacillin was the cause of bone marrow suppression in this patient.
  
  
  CONCLUSIONS
  Bone marrow suppression is a serious adverse effect of piperacillin, which should be kept in mind while treating patients with this drug.
authors.affiliation: Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India. ashishk@sgpgi.ac.in
authors.forename: Ashish
authors.initials: A
authors.lastname: Kumar
authors.forename: Gourdas
authors.initials: G
authors.lastname: Choudhuri
authors.forename: Rakesh
authors.initials: R
authors.lastname: Aggarwal
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001855:Bone Marrow Diseases / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010878:Piperacillin / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D010878:Piperacillin