title: Rapidly repeated intravenous boluses of salbutamol for acute severe asthma.
abstract: We describe the use of intravenous boluses of salbutamol given rapidly (over 1-2 min) in children (5 microg x kg-1) and young adults (250 microg) with acute severe asthma who were not improving with doses of nebulised salbutamol. Intravenous boluses were repeated within a short time until improvement was seen. Two of the seven patients required tracheal intubation and ventilation.
authors.affiliation: Kettering General Hospital, Kettering, NN16 8SH, UK. wfsellers@hotmail.com
authors.forename: W F S
authors.initials: WF
authors.lastname: Sellers
authors.forename: B
authors.initials: B
authors.lastname: Messahel
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage* / Q000627:therapeutic use; D000420:Albuterol / Q000008:administration & dosage* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D008297:Male
chemical_list: D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D000420:Albuterol