title: Chemical and cytotoxic constituents from Peperomia sui.
abstract: Three polyketide compounds, surinone A, surinone B, surinone C and one acylresorcinol, suranone, along with thirty known compounds, were isolated from the whole plant of Peperomia sui. Their structures were elucidated from spectral analysis. Several compounds showed cytotoxic activity against HONE-1 and NUGC-3 cell lines in vitro.
authors.affiliation: Graduate Institute of Pharmaceutical Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan 807, Republic of China.
authors.forename: Ming-Jen
authors.initials: MJ
authors.lastname: Cheng
authors.forename: Shoiw-Ju
authors.initials: SJ
authors.lastname: Lee
authors.forename: Ying-Ying
authors.initials: YY
authors.lastname: Chang
authors.forename: Szu-Huei
authors.initials: SH
authors.lastname: Wu
authors.forename: Ian-Lih
authors.initials: IL
authors.lastname: Tsai
authors.forename: Bolleddula
authors.initials: B
authors.lastname: Jayaprakasam
authors.forename: Ih-Sheng
authors.initials: IS
authors.lastname: Chen
mesh_terms: D000475:Alkenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D003510:Cyclohexanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D007659:Ketones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D036941:Peperomia / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000475:Alkenes; D003510:Cyclohexanes; D007659:Ketones; C477209:suranone; C477208:surinone A; C477207:surinone B; C477206:surinone C