Was it there all the time?
The complement system is old, yet it may still have something new to teach us. For many years, research has existed which shows that C3d, in addition to its established role as an adjuvant, could have an immunosuppressive activity. Being true, it suggests that a common mechanism may be used both by organisms and by their pathogens to prevent unwanted immune responses.
Bennett
M
M
Section for Immunology, BMC, Lund University, Lund, Sweden.
Leanderson
T
T
D000818:Animals; D017209:Apoptosis / Q000276:immunology; D005075:Biological Evolution; D003167:Complement Activation; D015933:Complement C3d / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D003165:Complement System Proteins; D006801:Humans; D007108:Immune Tolerance; D018448:Models, Immunological; D008958:Models, Molecular; D017464:Receptors, Complement 3d / Q000502:physiology; D015398:Signal Transduction
D017464:Receptors, Complement 3d; D015933:Complement C3d; D003165:Complement System Proteins