Apoptosis: a mechanism of cell suicide.
In this paper, a general overview on apoptosis (or programmed cell death) is given together with a brief description of the major features characterizing apoptotic cells. Then the most important pathways of apoptosis are described. Thereafter the roles of caspases and the Bcl-2 family members on apoptosis are explained.
Derradji
Hanane
H
Laboratory of Radiobiology, Belgian Nuclear Research Centre, SCK-CEN, Boeretang 200, B-2400 Mol, Belgium. Hderradj@sckcen.be
Baatout
Sarah
S
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D020169:Caspases / Q000502:physiology; D006801:Humans; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000502:physiology
D019253:Proto-Oncogene Proteins c-bcl-2; D020169:Caspases