title: Randomized controlled trial comparing argon plasma coagulation tonsillectomy with conventional techniques.
abstract: Argon plasma coagulation (APC) is based on the principle of ionized argon creating a conductive plasma between an activating electrode and a tissue surface. To date, its use in tonsillectomy has not been extensively examined. The purpose of this randomized controlled trial was to assess the clinical efficacy of APC as a tool for this common surgical procedure. Forty patients were randomized into two groups--treatment A (conventional tonsillectomy, n = 20) and treatment B (APC tonsillectomy, n = 20). Trial end-points included a) operative time, b) intra-operative blood loss, and c) objective assessment of post-operative pain, by completion of a visual analogue pain score chart, over a two-week period. Thirty-one patients were available for analysis. There was a statistically significant reduction in the intra-operative blood loss with treatment B (p = 0.02). There was no statistical difference between both groups for the other outcome measures. First clinical experience with this treatment modality shows that it is an attractive alternative to conventional tonsillectomy and may offer possible benefits.
authors.affiliation: Department of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin 2, Ireland. skinnerljs@yahoo.com
authors.forename: Liam J
authors.initials: LJ
authors.lastname: Skinner
authors.forename: Michael P
authors.initials: MP
authors.lastname: Colreavy
authors.forename: Eimear
authors.initials: E
authors.lastname: Lang
authors.forename: Brendan
authors.initials: B
authors.lastname: O'Hare
authors.forename: David A
authors.initials: DA
authors.lastname: Charles
authors.forename: Conrad I
authors.initials: CI
authors.lastname: Timon
mesh_terms: D000293:Adolescent; D000328:Adult; D001128:Argon; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D004564:Electrocoagulation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D014068:Tonsillectomy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D001128:Argon