title: [Antitubercular drug treatment failure and HIV infection in Abidjan (Ivory Coast)].
abstract: A retrospective study from 1989 to 1993 was carried out on eighty patients out of 106 cases of tuberculosis treatment failure; representing 2.2% of persons with active pulmonary tuberculosis followed at the tuberculosis screening center of Abidjan. The rate of HIV seropositivity was 43.7%. At the beginning of the therapy, 80% of HIV-positive and 89% of HIV-negative had diffuse pulmonary lesions (no significant difference: P > 0.05. At the end of second month therapy, 49% of co-infected and 51% of HIV-negative patients showed bacteriological negative sputum. The treatment administered after reporting failure, led to 63% of recovery among the HIV-positive (22/35) and 62% among the HIV-negative (28/45). On the other hand, the rate of patients out of touch was high in both populations; respectively 29% of HIV infected and 31% of HIV-negative spreading the risk of contamination of neighbourhood by probably resistant bacilli.
authors.affiliation: Service de pneumo-phtisiologie, CHU de Treichville, BP V 3, Abidjan, Côte d'Ivoire.
authors.forename: T
authors.initials: T
authors.lastname: Daix
authors.forename: K
authors.initials: K
authors.lastname: Domoua
authors.forename: G
authors.initials: G
authors.lastname: Coulibaly
authors.forename: H
authors.initials: H
authors.lastname: Kissi
authors.forename: L
authors.initials: L
authors.lastname: Beugre-Sy
authors.forename: A
authors.initials: A
authors.lastname: Yapi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D007560:Cote d'Ivoire / Q000453:epidemiology; D005260:Female; D018023:HIV Seronegativity; D015528:HIV Seroprevalence; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013183:Sputum / Q000382:microbiology; D017211:Treatment Failure; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents