title: Transvaginal sonography in the diagnosis of pelvic malignant recurrence: integration of sonography and needle-guided biopsy.
abstract: The aim of this study was to evaluate the efficiency of transvaginal sonography and sonography plus needle biopsy in detecting pelvic malignant recurrence. We scanned 24 patients already treated for gynecological malignancy, 21 of whom underwent needle biopsy under sonographic guidance. Thirteen patients were affected by cervical cancer, ten by ovarian cancer, and one by endometrial-ovarian carcinoma. Sonography detected 16 solid or cystic-solid masses (median size 52 mm, range 15-85 mm), one case of ascites, and one liquid mass (hematoma). All the patients in whom a suspicious mass was detected had recurrence. In the six patients in whom no mass was visible, two had recurrence. Needle biopsy was able to demonstrate recurrence in 17 patients (also in two false-negative scans). In one, even though sonography detected a mass, the histological sample was negative, but recurrence was later diagnosed by laparotomy.Accuracy, sensitivity and specificity of transvaginal sonography were respectively 91.6%, 89.4% and 100%. The positive predictive value was 100% and the negative predictive value was 71.4%. Transvaginal sonography was shown to be a useful means of detecting pelvic recurrence.
authors.affiliation: University of Turin, Institute of Obstetrics and Gynecology, Department of Gynecological Oncology, Turin, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Volpi
authors.forename: P
authors.initials: P
authors.lastname: Zola
authors.forename: T
authors.initials: T
authors.lastname: De Grandis
authors.forename: A
authors.initials: A
authors.lastname: Rumore
authors.forename: T
authors.initials: T
authors.lastname: Volpe
authors.forename: P
authors.initials: P
authors.lastname: Sismondi