title: Expression of cVg1 mRNA during chicken embryonic development.
abstract: Using degenerated PCR-primers to identify known and novel BMPs that are expressed in the developing chicken heart, we identified not only BMP2, -4, and -7 mRNA, but also the TGFbeta superfamily member cVg1. The expression pattern of cVg1 mRNA was determined during chicken development from HH4 to HH44. In early developmental stages, cVg1 mRNA is expressed in the primitive streak, paraxial mesoderm, developing somites, and developing neural tube. Subsequently, cVg1 mRNA is expressed in the developing central and peripheral nervous system, retina, auditory vesicle, notochord, lung alveoli, and olfactory mucosa. In the heart, cVg1 is initially expressed through the linear heart tube, but becomes restricted to the forming chamber myocardium, in an expression domain similar to that of atrial natriuretic factor (ANF) mRNA.
authors.affiliation: Experimental and Molecular Cardiology Group, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Semir
authors.initials: S
authors.lastname: Somi
authors.forename: Arjan C
authors.initials: AC
authors.lastname: Houweling
authors.forename: Anita A M
authors.initials: AA
authors.lastname: Buffing
authors.forename: Antoon F M
authors.initials: AF
authors.lastname: Moorman
authors.forename: Maurice J B
authors.initials: MJ
authors.lastname: Van Den Hoff
mesh_terms: D000818:Animals; D055396:Bone Morphogenetic Protein 2; D055415:Bone Morphogenetic Protein 4; D055419:Bone Morphogenetic Protein 7; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000378:metabolism; D002490:Central Nervous System / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D002642:Chick Embryo / Q000254:growth & development / Q000378:metabolism*; D005123:Eye / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D005775:Gastrula / Q000378:metabolism; D020869:Gene Expression Profiling; D006023:Glycoproteins / Q000235:genetics / Q000378:metabolism*; D006321:Heart / Q000196:embryology / Q000254:growth & development; D008648:Mesoderm / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D009672:Notochord / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D009831:Olfactory Mucosa / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D017933:Peripheral Nervous System / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D011650:Pulmonary Alveoli / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D012333:RNA, Messenger / Q000032:analysis; D012679:Sense Organs / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D019170:Somites / Q000378:metabolism; D016212:Transforming Growth Factor beta / Q000378:metabolism
chemical_list: D055396:Bone Morphogenetic Protein 2; D055415:Bone Morphogenetic Protein 4; D055419:Bone Morphogenetic Protein 7; D019485:Bone Morphogenetic Proteins; D006023:Glycoproteins; D012333:RNA, Messenger; D016212:Transforming Growth Factor beta