Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine.
Pascale
E
E
Battiloro
E
E
Cimino Reale
G
G
Pietrobono
R
R
Pomponi
M G
MG
Chiurazzi
P
P
Nicolai
R
R
Calvani
M
M
Neri
G
G
D'Ambrosio
E
E
D000108:Acetylcarnitine / Q000627:therapeutic use*; D002331:Carnitine / Q000627:therapeutic use*; D002478:Cells, Cultured; D019175:DNA Methylation / Q000187:drug effects*; D051860:Fragile X Messenger Ribonucleoprotein 1; D005600:Fragile X Syndrome / Q000188:drug therapy / Q000235:genetics; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000378:metabolism*; D018697:Nootropic Agents / Q000627:therapeutic use; D011401:Promoter Regions, Genetic / Q000187:drug effects*; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism
D000108:Acetylcarnitine; D002331:Carnitine; D051860:Fragile X Messenger Ribonucleoprotein 1; D009419:Nerve Tissue Proteins; D018697:Nootropic Agents; D016601:RNA-Binding Proteins; C497683:FMR1 protein, human