Connectivity optimization and the positioning of cortical areas.
By examining many alternative arrangements of cortical areas, we have found that the arrangement actually present in the brain minimizes the volume of the axons required for interconnecting the areas. Our observations support the notion that the organization of cortical areas has evolved to optimize interareal connections.
Klyachko
Vitaly A
VA
Howard Hughes Medical Institute and Molecular Neurobiology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Stevens
Charles F
CF
D001369:Axons; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D006801:Humans; D015233:Models, Statistical; D016011:Normal Distribution; D017397:Prefrontal Cortex / Q000033:anatomy & histology* / Q000502:physiology