title: Thermosensation: hot findings make TRPNs very cool.
abstract: TRPV and TRPM proteins have been shown to form temperature-responsive cation channels that act in nociception. Recent work on the mouse ANKTM1 and Drosophila Painless proteins shows that members of a third TRP subfamily, TRPN, also function in thermosensation.
authors.affiliation: Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. cmontell@jhmi.edu
authors.forename: Craig
authors.initials: C
authors.lastname: Montell
mesh_terms: D000818:Animals; D003080:Cold Temperature; D029721:Drosophila Proteins / Q000502:physiology; D007473:Ion Channels / Q000502:physiology*; D017434:Protein Structure, Tertiary; D000074025:TRPA1 Cation Channel; D013697:Thermosensing / Q000502:physiology*; D050051:Transient Receptor Potential Channels
chemical_list: D029721:Drosophila Proteins; D007473:Ion Channels; D000074025:TRPA1 Cation Channel; D050051:Transient Receptor Potential Channels; C475685:Trpa1 protein, mouse; C474592:pain protein, Drosophila