Radical resection of giant congenital melanocytic nevus and reconstruction with meek-graft covered integra dermal template.
BACKGROUND
Giant congenital melanocytic nevi represent a surgical challenge, particularly in cases in which the size of the nevus exceeds certain extend and malignant transformations have to be considered.


OBJECTIVE
To discuss through case report considerable surgical options when extensive giant congenital melanocytic nevi with malignant transformation are encountered.


METHODS
We present an unusual case of a giant congenital melanocytic nevi of the entire back of a 44-year-old patient. To achieve radical resection with direct appropriate wound closure and acceptable outcome, the integument of the entire back was excised and covered with Integra, followed by split-thickness skin grafting after stable integration of the matrix.


RESULTS
The approach resulted in a complete excision of the tumor and acceptable cosmetic and excellent biomechanical outcome.


CONCLUSIONS
The introduced practice demonstrates a useful alternative to established methods, particularly if tumor excision in large areas and subsequent wound closure might be achieved in one procedure.
Kopp
Jürgen
J
Department of Plastic and Reconstructive Surgery, Hand Surgery, Burn Center, Aachen, Germany. juergen.kopp@chir.imed.uni-erlangen.de
Magnus Noah
E
E
Rübben
Albert
A
Merk
Hans F
HF
Pallua
Norbert
N
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001365:Axilla; D001415:Back; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic; D002809:Chondroitin Sulfates; D003094:Collagen; D005260:Female; D006119:Groin; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D008197:Lymph Node Excision / Q000379:methods; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D009508:Nevus, Pigmented / Q000473:pathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods*; D017768:Skin, Artificial
D000970:Antineoplastic Agents; D001672:Biocompatible Materials; D016898:Interferon-alpha; C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen