Fine needle aspiration cytology of neurothekeoma. A case report.
BACKGROUND
Neurothekeoma (NT) is a rare, benign neoplasm of soft parts with a distinctive histologic appearance. To our knowledge, the cytologic findings have not been described before. We present a case of NT with the cytologic features on fine needle aspiration cytology (FNAC).


METHODS
A 54-year-old female presented with a circumscribed nodule in the left breast. The lesion was evaluated by FNAC. The smears showed an abundant, metachromatic, myxoid matrix with fusiform and epithelioid cells, some binucleated or multinucleated, loose or in groups and sometimes forming concentric whorls. The lesion was removed, and the diagnosis of NT was made after histopathologic study.


CONCLUSIONS
NT is an extremely rare neoplasm in the mammary region. Fusiform and epithelioid cells arranged in concentric whorls in a myxoid tumor of soft tissue are a distinctive characteristic of this neoplasm and can suggest the diagnosis.
Vaillo Vinagre
Agustín
A
Cytology Unit, Department of Pathology, University Hospital 12 de Octubre, Ctra Andalucía Km. 5.400, Madrid, Spain.
Gutiérrez Martín
Antonia
A
Pérez Barrios
Andrés
A
Alberti Masgrau
Nuria
N
Ballestín Carcavilla
Claudio
C
De Agustín De Agustín
Pedro
P
D014408:Biomarkers, Tumor / Q000032:analysis; D001707:Biopsy, Needle / Q000379:methods*; D001940:Breast / Q000473:pathology* / Q000601:surgery; D015622:Epithelioid Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D018321:Neurothekeoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014746:Vimentin / Q000032:analysis
D014408:Biomarkers, Tumor; D014746:Vimentin