Decompensated hepatitis B virus-related cirrhosis successfully treated with lamivudine allowing surgery for hepatocellular carcinoma.
A 39-year-old man was diagnosed with hepatitis B virus-related cirrhosis, and because of hepatic exacerbations with icterus and ascites, he had been repeatedly hospitalized. He was treated with lamivudine. Several months later, his ascites disappeared and his liver function was improved from class C to A according to the Child-Pugh classification. Two years later, one small hepatocellular carcinoma was detected, and he underwent a successful hepatectomy. From this case, we consider lamivudine to be useful for improving hepatic function in decompensated liver cirrhosis type B and lamivudine might enable surgical resection of hepatocellular carcinoma.
Nakanishi
Seiji
S
Third Department of Internal Medicine, Ehime University School of Medicine, Onsen-gun, Ehime.
Michitaka
Kojiro
K
Miyake
Teruki
T
Hidaka
Satoshi
S
Yoshino
Itaru
I
Konishi
Ichiro
I
Iuchi
Hidehito
H
Horiike
Norio
N
Onji
Morikazu
M
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006498:Hepatectomy; D006509:Hepatitis B / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use*; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D008297:Male; D011859:Radiography
D000998:Antiviral Agents; D019259:Lamivudine