title: Characterization of arterial stenosis and elasticity by analysis of high-frequency pressure wave components.
abstract: We describe a novel method for assessing stenosis severity based on pressure wave measurements. Pressure waves for several degrees of stenosis at different distances proximal to the stenosis were recorded from in vitro and in vivo models. Signal analysis was performed using power spectral density, and radial compliance was also measured. Pressure wave components at the acoustic frequency band (400-2500Hz) changed gradually and were dependent upon the distance from the stenosis and its severity. The shift of the pressure components could also demonstrate the elastic properties of tubes and arteries and explain the effect of a bifurcation in the system.
authors.affiliation: Neufeld Cardiac Research Institute, Tel-Aviv University, Tel Aviv Israel and the Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Zehava
authors.initials: Z
authors.lastname: Ovadia-Blechman
authors.forename: Shmuel
authors.initials: S
authors.lastname: Einav
authors.forename: Uri
authors.initials: U
authors.lastname: Zaretsky
authors.forename: David
authors.initials: D
authors.lastname: Castel
authors.forename: Michael
authors.initials: M
authors.lastname: Eldar
mesh_terms: D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D003251:Constriction, Pathologic / Q000503:physiopathology*; D004548:Elasticity; D006801:Humans; D011312:Pressure