C-Nucleosidations with 2,6-diamino-5,8-diaza-7,9-dicarba-purine.
[structure: see text] Endocyclic iminium ions derived from l-4-amino-threose derivatives smoothly react with 2,6-diamino-5,8-diaza-7,9-dicarba-purine to give corresponding C(9)-nucleosides in high yields.
Han
Bo
B
The Skaggs Institute for Chemical Biology at the Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Wang
Zhijun
Z
Jaun
Bernhard
B
Krishnamurthy
Ramanarayanan
R
Eschenmoser
Albert
A
D015075:2-Aminopurine / Q000031:analogs & derivatives* / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D011684:Purine Nucleosides / Q000138:chemical synthesis*; D011687:Purines / Q000737:chemistry*; D013780:Tetroses / Q000737:chemistry
C478254:2,6-diamino-5,8-diaza-7,9-dicarba-purine; D001372:Aza Compounds; D007097:Imines; D011684:Purine Nucleosides; D011687:Purines; D013780:Tetroses; D015075:2-Aminopurine; C007300:2,6-diaminopurine; C073321:erythrose