Molecular and conventional epidemiology of tuberculosis in Hong Kong: a population-based prospective study.
A prospective population-based molecular and conventional epidemiological study of 65.4% of bacteriologically confirmed cases of tuberculosis was carried out on the island of Hong Kong from May 1999 to Oct 2000 by the IS6110-based restriction fragment length polymorphism technique. Eleven of the isolates had five or fewer bands; 24.5% of the remaining 691 isolates belonged to clusters. The estimated proportion of recently transmitted disease was 15 to 20%.
Chan-Yeung
Moira
M
Hong Kong Government Tuberculosis and Chest Service, Department of Health, The University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China.
Tam
Cheuk-Ming
CM
Wong
Harriet
H
Leung
Chi-Chiu
CC
Wang
Julie
J
Yew
Wing-Wai
WW
Lam
Chak-Wah
CW
Kam
Kai-Man
KM
D004251:DNA Transposable Elements; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011159:Population Surveillance; D011446:Prospective Studies; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology
D004251:DNA Transposable Elements