title: Treatment of skin malignancies.
abstract: Malignant melanomas in situ can usually be treated in consultation with a specialist (C). Larger lesions may require referral. Based on best available evidence, surgical excision is the first-line treatment for most nonmelanoma skin cancers, with cure rates as high as 98% with proper margins. Consider Mohs surgery for larger lesions, sclerosing lesions with morpheaform histology, or for cosmetically sensitive areas. With properly selected lesions, curettage/electrodesiccation and cryosurgery have cure rates comparable to that of surgical excision.
authors.affiliation: 470th Air Base, USAF Clinic, Geilenkirchen, Germany.
authors.forename: Peter L
authors.initials: PL
authors.lastname: Reynolds
authors.forename: Scott M
authors.initials: SM
authors.lastname: Strayer
mesh_terms: D000465:Algorithms; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003452:Cryosurgery; D003475:Curettage; D003663:Decision Trees; D004598:Electrosurgery; D019317:Evidence-Based Medicine; D005194:Family Practice; D006801:Humans; D008545:Melanoma / Q000175:diagnosis / Q000628:therapy*; D015580:Mohs Surgery; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D018714:Radiotherapy, Adjuvant; D012017:Referral and Consultation; D012307:Risk Factors; D012878:Skin Neoplasms / Q000175:diagnosis / Q000628:therapy*; D016019:Survival Analysis
chemical_list: D000970:Antineoplastic Agents