title: Endocrine paraneoplastic syndromes in lung cancer.
abstract: Lung tumors are capable of synthesizing and secreting peptide proteins (hormones) that lead to a variety of endocrine paraneoplastic syndromes. Knowledge about the clinical manifestations, pathophysiology, and treatment of these syndromes has evolved over time. This article provides an up-to-date overview of this knowledge.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA. mazzonp@ccf.org
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Mazzone
authors.forename: Alejandro C
authors.initials: AC
authors.lastname: Arroliga
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism*; D014667:Vasopressins / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D044162:Parathyroid Hormone-Related Protein; D014667:Vasopressins; D000324:Adrenocorticotropic Hormone