Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature.
Chordoid gliomas are an uncommon primary brain tumor with histologic features of a chordoma and immunolabeling for glial fibrillary acid protein. We report the 32nd case with a review of the literature. The clinical, radiographic and pathologic features of the tumor are presented with new pathologic findings adding support that this lesion may be of ependymal origin. Treatment and long term outcome are limited but chordoid gliomas appear to be indolent lesions that may be cured with gross total resection.
Raizer
Jeffrey J
JJ
Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. raizerj@mskcc.org
Shetty
Teena
T
Gutin
Philip H
PH
Obbens
Eugenie A
EA
Holodny
Andrei I
AI
Antonescu
Cristina R
CR
Rosenblum
Marc K
MK
D001932:Brain Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000648:ultrastructure*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D005910:Glioma / Q000737:chemistry / Q000175:diagnosis / Q000648:ultrastructure*; D006801:Humans; D007124:Immunoenzyme Techniques; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020542:Third Ventricle / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D005904:Glial Fibrillary Acidic Protein