title: Redistribution and unmasking of Annexin V binding sites in apoptotic Raji cells.
abstract: The complement receptor type 2 (CR2) associates with other surface antigens and proteins and its redistribution and/or unmasking occurs through still unknown mechanism(s). The data presented demonstrate that high-density cultured CR2-positive cells undergo apoptosis and that the redistribution and unmasking of Annexin V binding sites occurs in a fashion similar to the redistribution and unmasking of CR2. Therefore, apoptotic and non apoptotic cells from the same lineage may share a similar mechanism for the exposition of neo-surface markers
authors.affiliation: Istituto di Biologia e Patologia Molecolare, CNR, V.le Marx 43, Rome 00137, Italy.
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: di Certo
authors.forename: Alberto
authors.initials: A
authors.lastname: Faggioni
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Barile
mesh_terms: D017304:Annexin A5 / Q000378:metabolism*; D000954:Antigens, Surface; D017209:Apoptosis / Q000276:immunology*; D001665:Binding Sites / Q000276:immunology; D019070:Cell Lineage / Q000276:immunology*; D002462:Cell Membrane / Q000378:metabolism*; D005434:Flow Cytometry; D006801:Humans; D008024:Ligands; D011485:Protein Binding / Q000276:immunology; D017464:Receptors, Complement 3d / Q000378:metabolism*; D014407:Tumor Cells, Cultured
chemical_list: D017304:Annexin A5; D000954:Antigens, Surface; D008024:Ligands; D017464:Receptors, Complement 3d