Aid to the antemortem diagnosis of Fell pony foal syndrome by the analysis of B lymphocytes.
Fell pony foals are affected by a congenital fatal immunodeficiency that commonly leads to anaemia and lymphopenia. Previous work has shown that the foals' circulating subpopulations of CD4 and CD8 T lymphocytes are unaffected. In this study it was shown that the mean population of B lymphocytes in 10 affected foals was less than 10 per cent of that in normal foals.
Thomas
G W
GW
Department of Veterinary Pathology, University of Liverpool, Liverpool L69 7ZJ.
Bell
S C
SC
Phythian
C
C
Taylor
P
P
Knottenbelt
D C
DC
Carter
S D
SD
D000818:Animals; D000831:Animals, Newborn; D001402:B-Lymphocytes / Q000166:cytology* / Q000276:immunology; D005434:Flow Cytometry; D006734:Horse Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006736:Horses; D007153:Immunologic Deficiency Syndromes / Q000097:blood / Q000175:diagnosis* / Q000276:immunology / Q000662:veterinary*; D018655:Lymphocyte Count; D013577:Syndrome