title: [Newborn hydronephrosis: dynamic renal scintigraphy with Tc99m MAG3 in the first month of life].
abstract: BACKGROUND
  The early and accurate diagnosis of obstructive uropathy in the newborn, prevents secondary complications and kidney damage.
  
  
  OBJECTIVE
  To study the usefulness of Tc99M MAG3 diuretic renogram in newborns with hydronephrosis.
  
  
  METHODS
  Forty newborns, aged 1 to 30 days, with hydronephrosis, were studied. A Tc99M MAG3 diuretic renogram (DR) was done and its results were compared with clinical features and other imaging studies. Each kidney and its ureter, were considered a renal unit.
  
  
  RESULTS
  Seventy six renal units were evaluated. Twenty six were normal on prenatal ultrasound examination and DR. In 11 of the 50 renal units with hydronephrosis, renal function was impaired. Thus, it was impossible to obtain an excretory curve. In 17 of the 39 remaining renal units, the absence of obstructive uropathy was demonstrated clinically. In 16 of these, the DR showed absence of obstruction. In 20 of 21 renal units with confirmed obstructive uropathy, DR showed an obstructive pattern.
  
  
  CONCLUSIONS
  In newborns, there is an adequate Tc99M MAG3 uptake and diuretic response. Thus, DR becomes a good functional assessment method in newborns with hydronephrosis.
authors.affiliation: Departamentos de Radiología, Pediatría, Urología, Laboratorio de Medicina Nuclear, Hospital Clínico, Facultad de Medicina, Pontificia Universidad Católica de Chile. pilar@med.puc.cl
authors.forename: Pilar
authors.initials: P
authors.lastname: Orellana
authors.forename: Paulina
authors.initials: P
authors.lastname: Baquedano
authors.forename: Felipe
authors.initials: F
authors.lastname: Cavagnaro
authors.forename: Edda
authors.initials: E
authors.lastname: Lagomarsino
authors.forename: Cristián
authors.initials: C
authors.lastname: García
authors.forename: Juan Eduardo
authors.initials: JE
authors.lastname: Carreño
authors.forename: Luis
authors.initials: L
authors.lastname: Meneses
mesh_terms: D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging* / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D011446:Prospective Studies; D011866:Radioisotope Renography; D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide; D014517:Ureteral Obstruction / Q000150:complications / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide