title: Toxicity of single and mixed contaminants in seawater measured with acute toxicity bioassays.
abstract: Different types of organic pollutants commonly detected in seawater have been evaluated by acute toxicity bioassays. Vibrio fischeri, Daphnia magna, and Selenastrum capricornotum were selected to test toxic effects of individual compounds and mixtures of these compounds, obtaining EC50 values in the range of 0.001 to 28.9 mg/l. In the case of mixtures, synergistic toxic responses were seen for a clear majority of the cases (>60%). Mixtures containing methyl-tertiary-butyl ether (MTBE) exhibit accelerated processes that result in a change in concentration required to produce a toxic effect; for example, in the case of mixtures containing MTBE and Diuron and Dichlofluanid.
authors.affiliation: Pesticide Residue Research Group, Faculty of Sciences, University of Almería, 04120, Almería, Spain. amadeo@ual.es
authors.forename: A R
authors.initials: AR
authors.lastname: Fernández-Alba
authors.forename: L
authors.initials: L
authors.lastname: Piedra
authors.forename: M
authors.initials: M
authors.lastname: Mezcua
authors.forename: M D
authors.initials: MD
authors.lastname: Hernando
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods*; D003621:Daphnia / Q000187:drug effects / Q000502:physiology; D056890:Eukaryota / Q000187:drug effects / Q000254:growth & development; D007928:Lethal Dose 50; D008163:Luminescent Measurements; D008738:Methyl Ethers / Q000633:toxicity; D009068:Movement / Q000187:drug effects / Q000502:physiology; D010575:Pesticides / Q000633:toxicity; D013997:Time Factors; D023382:Toxicity Tests, Acute / Q000379:methods*; D014733:Vibrio / Q000187:drug effects / Q000502:physiology; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D014881:Water Supply / Q000032:analysis
chemical_list: D008738:Methyl Ethers; D010575:Pesticides; D014874:Water Pollutants, Chemical; C043243:methyl tert-butyl ether