Glycosides of Atractylodes lancea.
Five sesquiterpenoid glycosides (two guaiane-type glycosides and three eudesmane-type glucosides) and a glucoside of an acetylene derivative were newly isolated from the water-soluble portion of the methanolic extract of Atractylodes lancea rhizome together with 26 known compounds. Their structures were characterized as atractyloside A 14-O-beta-D-fructofuranoside, (1S,4S,5S,7R,10S)-10,11,14-trihydroxyguai-3-one 11-O-beta-D-glucopyranoside, (5R,7R,10S)-isopterocarpolone beta-D-glucopyranoside, cis-atractyloside I, (2R,3R,5R,7R,10S)-atractyloside G 2-O-beta-D-glucopyranoside, and (2E,8E)-2,8-decadiene-4,6-diyne-1,10-diol 1-O-beta-D-glucopyranoside on the basis of chemical and spectroscopic investigation. The presence of six characteristic guaiane-type glucosides in both rhizomes of A. lancea and Atractylodes japonica suggested a close chemotaxonomic relationship between them.
Kitajima
Junichi
J
Showa Pharmaceutical University, Tokyo, Japan. Kitajima@ac.shoyaku.ac.jp
Kamoshita
Akane
A
Ishikawa
Toru
T
Takano
Akihito
A
Fukuda
Tatsuo
T
Isoda
Susumu
S
Ida
Yoshiteru
Y
D031174:Atractylodes / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*; D045789:Sesquiterpenes, Guaiane / Q000737:chemistry / Q000302:isolation & purification*; D012995:Solubility
D006027:Glycosides; D010936:Plant Extracts; D045787:Sesquiterpenes, Eudesmane; D045789:Sesquiterpenes, Guaiane