Synthesis of platinum complexes from N-benzyl-2-aminoethanethiol derivatives.
Twelve new platinum(II) complexes, analogs of cisplatin, containing a 2-aminoethanethiol N-substituted by several benzyl groups have been prepared and characterized in good yields. The ligands were obtained by reaction between 2-aminoethanethiol hydrochloride and different benzyl halides
de Almeida
Mauro Vieira
MV
Departamento de Química, UFJF, 36036-330, Juiz de Fora-MG, Brazil. mvieira@quimica.ufjf.br
de Oliviera
Laura Lúcia C
LL
Cesar
Eloi Teixeira
ET
de Souza
Marcus Vinícius N
MV
D001593:Benzyl Compounds / Q000737:chemistry*; D002945:Cisplatin / Q000031:analogs & derivatives / Q000737:chemistry; D003543:Cysteamine / Q000031:analogs & derivatives* / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*
D001593:Benzyl Compounds; D009942:Organometallic Compounds; D010984:Platinum; D003543:Cysteamine; D002945:Cisplatin