title: Optical coherence tomography findings in nicotinic acid maculopathy.
abstract: OBJECTIVE
  To report optical coherence tomography findings in nicotinic acid maculopathy.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  The patient was examined with ophthalmoscopy, fluorescein angiography, and optical coherence tomography.
  
  
  RESULTS
  A 71-year-old man presented with bilateral decreased visual acuity with metamorphopsia. Optical coherence tomography demonstrated cystoid spaces in the outer plexiform layer and inner nuclear layer. Fluorescein angiography did not show leakage. Two weeks after stopping the nicotinic acid, the cystoid spaces resolved.
  
  
  CONCLUSIONS
  Niacin maculopathy causes cystoid spaces in the inner nuclear and outer plexiform layers that resolve with discontinuation of the drug.
authors.affiliation: LuEsther T. Mertz Retina Research Laboratory, Manhattan Eye, Ear, and Throat Hospital, New York, New York 10021, USA.
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Spirn
authors.forename: Floyd A
authors.initials: FA
authors.lastname: Warren
authors.forename: David R
authors.initials: DR
authors.lastname: Guyer
authors.forename: James M
authors.initials: JM
authors.lastname: Klancnik
authors.forename: Richard F
authors.initials: RF
authors.lastname: Spaide
mesh_terms: D000368:Aged; D005451:Fluorescein Angiography; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000009:adverse effects*; D007368:Interferometry; D008027:Light; D008297:Male; D009525:Niacin / Q000009:adverse effects*; D009887:Ophthalmoscopy; D012160:Retina / Q000187:drug effects* / Q000473:pathology; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D014054:Tomography; D014786:Vision Disorders / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D000960:Hypolipidemic Agents; D009525:Niacin