title: Hormone replacement therapy and health protection.
abstract: Menopause is potentially a cause of concern and hormone-related diseases. Hormone replacement therapy (HRT) is considered to be an effective treatment strategy to relieve menopausal symptoms and prevent related diseases, however, knowledge on HRT and its benefits and risks is still evolving. For many climacteric women, HRT is the ideal choice to treat symptoms, prevent diseases and improve quality-of-life, while for others it can cause concerns and problems. Thus, the appropriate role of HRT has still to be fully defined. An individualized, patient-tailored approach to HRT, based on the current evidence of risk factors for hormone-related diseases and treatments, is essential to maximize the benefits and minimize the risks.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Bari, Corso Alcide de Gasperi 495, 70125 Bari, Italy. m.chiechi@gynecology3.uniba.it
authors.forename: Luigi Mario
authors.initials: LM
authors.lastname: Chiechi
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology; D003072:Cognition Disorders / Q000517:prevention & control; D015179:Colorectal Neoplasms / Q000517:prevention & control; D003327:Coronary Disease / Q000453:epidemiology; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D011372:Progestins / Q000009:adverse effects
chemical_list: D011372:Progestins