Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002.
Under the sponsorship of the International Extranodal Lymphoma Study Group, a Multidisciplinary Workshop on primary CNS lymphoma (PCNSL) with over 50 participants from Europe, North America, Israel, and Australia was held as part of the Eighth International Conference on Malignant Lymphoma in Lugano, Switzerland (June 12 to 15, 2002). The main purposes of the Workshop were to exchange the latest scientific information, to analyze methodologic issues in the design of clinical trials, to reach a consensus on treatment recommendations and prognostic factors, to discuss clinical and molecular targets for future studies, and to establish an international collaborative group to conduct laboratory and clinical investigations in PCNSL. This article summarizes the contents of the Workshop, analyzes the current knowledge on the most relevant biologic and clinical issues in PCNSL, and focuses on fundamental challenges to be addressed in future studies.
Ferreri
Andrés J M
AJ
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132, Milan, Italy. andres.ferreri@hsr.it
Abrey
Lauren E
LE
Blay
Jean-Yves
JY
Borisch
Bettina
B
Hochman
Jacob
J
Neuwelt
Edward A
EA
Yahalom
Joachim
J
Zucca
Emanuele
E
Cavalli
Franco
F
Armitage
James
J
Batchelor
Tracy
T
D000818:Animals; D016543:Central Nervous System Neoplasms / Q000235:genetics / Q000473:pathology / Q000628:therapy; D004195:Disease Models, Animal; D006801:Humans; D008223:Lymphoma / Q000235:genetics / Q000473:pathology / Q000628:therapy