The changing role of drug metabolism and pharmacokinetics.
The Pharmacokinetics and Drug Metabolism for Chemists meeting held November 13, 2001, in Stevenage, U.K., provided an interesting overview of how the drug metabolism and pharmacokinetics (DMPK) field has developed and the increasing importance, now recognized by most major companies, of obtaining DMPK data early in the drug discovery process. In addition to the repositioning of DMPK as a critical element of drug discovery, it was also made clear that the future should see fewer development compounds terminated because of DMPK factors.
Norman
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Norman Consulting, Burnham, Bucks, UK.