The effect of the presence of crown ether on ion transport across the lipid bilayer.
We studied the electric properties of phosphatidylcholine bilayers modified with crown ether (dibenzo[18] crown-6). The studies were carried out for various crown ether concentrations in forming solutions and various potassium ion concentrations in electrolyte solutions. The presence of crown ether in the membrane influences the membrane's impedance; there is a reduction in its resistivity, a decrease in its resistance of phase transfer and an increase in its capacity of phase transfer with an increase in crown ether concentration in the bilayer and in K(+) ion concentration in the electrolyte solution.
Naumowicz
Monika
M
Institute of Chemistry, University of Białystok, Al. J. Piłsudskiego 11/4, 15-443 Białystok, Poland.
Petelska
Aneta D
AD
Figaszewski
Zbigniew A
ZA
D043844:Crown Ethers / Q000494:pharmacology*; D017136:Ion Transport / Q000187:drug effects*; D008051:Lipid Bilayers / Q000378:metabolism*; D008564:Membrane Potentials / Q000187:drug effects; D010713:Phosphatidylcholines / Q000378:metabolism; D011188:Potassium / Q000378:metabolism
D043844:Crown Ethers; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D011188:Potassium