title: Histone-like proteins of the dinoflagellate Crypthecodinium cohnii have homologies to bacterial DNA-binding proteins.
abstract: The dinoflagellates have very large genomes encoded in permanently condensed and histoneless chromosomes. Sequence alignment identified significant similarity between the dinoflagellate chromosomal histone-like proteins of Crypthecodinium cohnii (HCCs) and the bacterial DNA-binding and the eukaryotic histone H1 proteins. Phylogenetic analysis also supports the origin of the HCCs from histone-like proteins of bacteria.
authors.affiliation: Department of Biology, Hong Kong University of Science and Technology, Kowloon, Hong Kong, People's Republic of China. Botin@ust.hk
authors.forename: J T Y
authors.initials: JT
authors.lastname: Wong
authors.forename: D C
authors.initials: DC
authors.lastname: New
authors.forename: J C W
authors.initials: JC
authors.lastname: Wong
authors.forename: V K L
authors.initials: VK
authors.lastname: Hung
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry* / Q000302:isolation & purification; D017124:Conserved Sequence; D004268:DNA-Binding Proteins / Q000737:chemistry* / Q000302:isolation & purification; D004141:Dinoflagellida / Q000235:genetics*; D029968:Escherichia coli Proteins; D005057:Eukaryotic Cells / Q000737:chemistry; D019143:Evolution, Molecular; D008969:Molecular Sequence Data; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C116822:hns protein, E coli