title: Future opportunities and developments for endoscopic gastroesophageal reflux disease therapy.
abstract: Endoscopic treatments for gastroesophageal reflux disease are directed at specific targets at the gastroesophageal junction. We explore the limitations and challenges of the anatomy, how current methods alter the anatomy and then speculate on the direction of future therapies.
authors.affiliation: Developmental Endoscopy Unit, Division of Gastroenterology and Hepatology, Eisenberg 8A, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: Jack I
authors.initials: JI
authors.lastname: Ramage
authors.forename: Arnaldo B
authors.initials: AB
authors.lastname: Feitoza
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Gostout
mesh_terms: D004943:Esophagogastric Junction / Q000473:pathology / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D005773:Gastroscopy / Q000379:methods / Q000639:trends*; D006801:Humans; D007267:Injections / Q000379:methods; D012106:Research