title: Inpatient length of stay and atypical antipsychotic use among elderly patients with psychiatric disorders and Alzheimer's disease.
abstract: This study evaluated length of stay (LOS) associated with atypical antipsychotic monotherapy in inpatients with Alzheimer's disease. In addition to sociodemographic information, data were also obtained on severity of illness, medications, used, patient satisfaction, and hospitalization. Sociodemographics and severity of illness at admission were similar in groups taking olanzapine (N = 66), quetiapine (N = 41), and risperidone (N = 147). The mean LOS for risperidone was significantly shorter than that for quetiapine (12.3 vs. 16.4 days, respectively; P < .02), but the difference between risperidone and olanzapine did not reach statistical significance (12.3 vs. 14.9 days, respectively; P < .08). The savings associated with risperidone versus quetiapine therapy, based on an estimated daily hospital care cost of $492, was $2,017.20 per patient.
authors.affiliation: Mental Health Outcomes, Lewisville, Texas, USA.
authors.forename: William S
authors.initials: WS
authors.lastname: Edell
authors.forename: Marcia F T
authors.initials: MF
authors.lastname: Rupnow
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy*; D014150:Antipsychotic Agents / Q000145:classification / Q000191:economics / Q000627:therapeutic use*; D001569:Benzodiazepines; D017046:Cost Savings; D003987:Dibenzothiazepines / Q000191:economics / Q000627:therapeutic use; D016527:Drug Costs; D017723:Drug Utilization Review; D005260:Female; D015577:Geriatric Assessment; D006302:Health Services Research; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data*; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy*; D000077152:Olanzapine; D010890:Pirenzepine / Q000031:analogs & derivatives* / Q000191:economics / Q000627:therapeutic use; D000069348:Quetiapine Fumarate; D018967:Risperidone / Q000191:economics / Q000627:therapeutic use; D014481:United States
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D001569:Benzodiazepines; D000069348:Quetiapine Fumarate; D010890:Pirenzepine; D018967:Risperidone; D000077152:Olanzapine