title: Color Doppler sonography of orbital and vertebral arteries in migraineurs without aura.
abstract: OBJECTIVE
  The objective of this study was to investigate whether the retrobulbar hemodynamics in the ophthalmic (OA), posterior ciliary (PCA), central retinal (CRA), and vertebral (VA) arteries are affected in migraineurs without aura.
  
  
  METHODS
  The eyes of migraineurs without aura and those of healthy control subjects were evaluated during both headache and headache-free periods. Retrobulbar and vertebral blood flow velocities in the OA, PCA, CRA, and the extracranial part of the VA were measured bilaterally using color Doppler sonography. The peak systolic and end-diastolic flow velocities and the pulsatility (PI) and resistance (RI) indices were determined for all arteries.
  
  
  RESULTS
  In total, we enrolled 30 migraineurs and 31 healthy control subjects. Statistically significant differences between headache-free migraineurs and control subjects were observed in the PI and RI of both right and left PCAs and in the RI of both right and left CRAs. The PI and RI of the left VA of the migraineurs were significantly lower during both headache and headache-free periods than were those of the control subjects. Among the migraineurs, the peak systolic and end-diastolic velocities of the left VA were increased during headache periods relative to those found during the headache-free periods.
  
  
  CONCLUSIONS
  The retrobulbar circulation and flow hemodynamics in the left VA may be altered in both headache and headache-free periods in migraineurs without aura. The differences found between migraineurs and control subjects may implicate autonomic dysfunction in migraineurs.
authors.affiliation: Department of Radiology, University of Kirikkale, School of Medicine, Sağlik Caddesi, Fabrikalar Mahallesi, 71100 Kirikkale, Turkey.
authors.forename: Simay Altan
authors.initials: SA
authors.lastname: Kara
authors.forename: A Kemal
authors.initials: AK
authors.lastname: Erdemoğlu
authors.forename: M Yasemin
authors.initials: MY
authors.lastname: Karadeniz
authors.forename: Deniz
authors.initials: D
authors.lastname: Altinok
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D019842:Ciliary Arteries / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology*; D009915:Orbit / Q000098:blood supply*; D012161:Retinal Artery / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color; D014711:Vertebral Artery / Q000000981:diagnostic imaging*