Glycoprotein B genotyping of  cytomegalovirus strains isolated in a pediatric population.
To better characterize cytomegalovirus (CMV) isolates in a pediatric population, we performed glycoprotein B genotyping of isolates from CMV culture-positive patients during a 3-year period at Children's Hospital Medical Center, Cincinnati, Ohio. The most common sources for CMV isolation were respiratory and urine cultures. Among 61 isolates glycoprotein B genotype distribution was genotype 1, 32%; genotype 2, 24%; genotype 3, 32%; and genotype 4, 10%. Among viremic isolates there was a trend favoring type 1 genotype (P = 0.057).
Xanthakos
Stavra A
SA
Division of Infectious Diseases, Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Schleiss
Mark R
MR
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003587:Cytomegalovirus / Q000235:genetics* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000453:epidemiology / Q000235:genetics; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005838:Genotype; D006023:Glycoproteins / Q000235:genetics*; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D014766:Viremia / Q000453:epidemiology / Q000235:genetics
D004279:DNA, Viral; D006023:Glycoproteins