title: The role of the carbachol test and concomitant diseases in patients with nonobstructive urinary retention undergoing sacral neuromodulation.
abstract: The aim of this study was to evaluate the percutaneous nerve evaluation (PNE) test success in patients with nonobstructive urinary retention. A total of 24 PNE tests were performed in patients with nonobstructive urinary retention and in 18 patients, a carbachol test was performed during urodynamics. The diagnosis relating to the acontractile detrusor was also assessed and compared to the outcome of the PNE test. The PNE test was successful in eight of 24 patients (33.3%) with the the highest success rate being observed in patients after hysterectomy (80%). It was successful in five of 12 patients with negative carbachol tests and in three of six patients with positive carbachol tests. We conclude that sacral neuromodulation is an effective treatment option in patients with nonobstructive urinary retention. PNE tests should be performed in all patients with therapy resistant nonobstructive urinary retention, because predictive factors do not exist.
authors.affiliation: Department of Urology, University Hospital Mannheim gGmbH, Theodor-Kutzer-Ufer 1-3, 68135 Mannheim, Germany. stephan.bross@uro.ma.uni-heidelberg.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Bross
authors.forename: Peter M
authors.initials: PM
authors.lastname: Braun
authors.forename: Joachim
authors.initials: J
authors.lastname: Weiss
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Martinez Portillo
authors.forename: Thomas
authors.initials: T
authors.lastname: Knoll
authors.forename: Christoph
authors.initials: C
authors.lastname: Seif
authors.forename: Klaus P
authors.initials: KP
authors.lastname: Juenemann
authors.forename: Peter
authors.initials: P
authors.lastname: Alken
mesh_terms: D000328:Adult; D000368:Aged; D002217:Carbachol; D018679:Cholinergic Agonists; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D008160:Lumbosacral Plexus / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000294:innervation / Q000503:physiopathology; D009422:Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D011237:Predictive Value of Tests; D001743:Urinary Bladder / Q000294:innervation / Q000503:physiopathology; D016055:Urinary Retention / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D014563:Urodynamics / Q000502:physiology
chemical_list: D018679:Cholinergic Agonists; D002217:Carbachol