Concurrent infectious mononucleosis and measles: a potentially life-threatening association sharing underlying immunodeficiency.
We report lethal interstitial pneumonia in an 18-year-old young man with measles infection following recent infectious mononucleosis. We speculate that the documented T cell immune impairment caused by the concurrent Epstein-Barr and measles viral infections (as expressed by a proportionately low CD4+ lymphocyte count) was responsible for the complicated clinical course and unfavorable outcome.
Manfredi
Roberto
R
Division of Infectious Diseases, Department of Clinical and Experimental Medicine, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Coronado
Olga V
OV
Mastroianni
Antonio
A
Chiodo
Francesco
F
D000293:Adolescent; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008457:Measles / Q000150:complications* / Q000175:diagnosis; D008459:Measles virus / Q000302:isolation & purification*; D011024:Pneumonia, Viral / Q000150:complications* / Q000175:diagnosis; D018570:Risk Assessment; D012720:Severity of Illness Index