Efficacy of Prostant on chronic prostatitis in 119 patients.
OBJECTIVE
To evaluate the efficacy and safety of Prostant in the treatment of chronic prostatitis.


METHODS
One hundred and nineteen cases of patients who had been diagnosed of chronic prostatitis were treated by Prostant. The efficacy was evaluated by WBC in EPS and NIH Chronic Prostatitis Symptom Index after a one-month follow-up.


RESULTS
After the one-month follow-up, the total improvement rate is 65.5 %, the WBC in the prostatic fluid were reduced from (21+/-20) to (12+/-13)/High-power field (HPF); the symptom index score changed from 12+/-4 to 7+/-5. The pain and voiding score of the symptom index were lowered from 8+/-3 to 5+/-3 and 3.9+/-2.7 to 2.3+/-2.3 respectively. All of above showed great statistic differences (P<0.05). Only 2 cases (1.7 %) reported serious diarrhea.


CONCLUSIONS
The Prostant is effective and safe in the treatment of chronic prostatitis, especially on those cases whose symptom and inflammation in prostatic fluid are not too serious.
Xu
Gang
G
Department of Urology, Shanghai Huashan Hospital, Fudan University, Shanghai 200040, China. moongang@online.sh.cn, drxugang@hotmail.com
Zhang
Yuan-Fang
YF
Ding
Qiang
Q
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D005500:Follow-Up Studies; D032062:Gardenia / Q000737:chemistry; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D032102:Phellodendron / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry; D011472:Prostatitis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D013488:Suppositories
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D013488:Suppositories; C482664:prostant