Minocycline-induced staining of torus palatinus and alveolar bone.
BACKGROUND
Minocycline hydrochloride, an analog of tetracycline, is widely used in the treatment of acne. Its use has been associated with discoloration of teeth, bone, and other tissues.


METHODS
A case is presented involving a patient with minocycline-induced staining of the torus palatinus and alveolar bone.


RESULTS
No treatment was rendered since the patient was not concerned with the appearance of the discoloration. The patient's dermatologist elected to change antibiotics.


CONCLUSIONS
Patients on long-term minocycline therapy should be made aware of the possibility of pigmentation of bone and soft tissue that may be reversible with discontinuation of therapy; however, minocycline-induced staining of the permanent dentition may not be reversible.
Ayangco
Lilibeth
L
Periodontics, Department of Dental Specialties, Mayo Clinic, Rochester, MN 55905, USA.
Sheridan
Phillip J
PJ
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000539:Alveolar Process / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005096:Exostoses / Q000473:pathology*; D005260:Female; D006801:Humans; D008439:Maxillary Diseases / Q000473:pathology*; D008911:Minocycline / Q000009:adverse effects*; D010159:Palate / Q000187:drug effects*; D010859:Pigmentation Disorders / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D008911:Minocycline