Generation of food-grade lactococcal starters which produce the lantibiotics lacticin 3147 and lacticin 481.
Transconjugant lactococcal starters which produce both lantibiotics lacticin 3147 and lacticin 481 were generated via conjugation of large bacteriocin-encoding plasmids. A representative of one of the resultant strains proved more effective at killing Lactobacillus fermentum and inhibiting the growth of Listeria monocytogenes LO28H than either of the single bacteriocin-producing parental strains, demonstrating the potential of these transconjugants as protection cultures for food safety applications.
O'Sullivan
Lisa
L
Dairy Products Research Centre, Teagasc, Moorepark, Fermoy, County Cork, Republic of Ireland.
Ryan
Maire P
MP
Ross
R Paul
RP
Hill
Colin
C
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000494:pharmacology; D001430:Bacteriocins; D002611:Cheese / Q000382:microbiology*; D003227:Conjugation, Genetic; D007778:Lactobacillus / Q000187:drug effects; D013294:Lactococcus lactis / Q000235:genetics* / Q000378:metabolism; D008089:Listeria monocytogenes / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010957:Plasmids
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001430:Bacteriocins; C082508:lacticin 481