title: Acute macular pucker.
abstract: OBJECTIVE
  To describe the presenting features, histopathology, and surgical outcome in a group of patients with rapidly progressive macular pucker.
  
  
  METHODS
  Retrospective interventional noncomparative case series.
  
  
  METHODS
  Five patients.
  
  
  METHODS
  Review of case notes and the existing literature.
  
  
  RESULTS
  All five patients had rapidly progressive visual loss and metamorphopsia over 2 weeks to 3 months, secondary to macular pucker after retinal tears or detachment. Vitrectomy and epiretinal membrane removal was performed within 1 month of diagnosis. In the absence of complications, there was rapid recovery of the visual acuity with resolution of metamorphopsia within 6 weeks to 3 months. Surgical complications limited the visual outcome in two cases. Histopathologic examination of epiretinal membrane removed from two of the cases suggests that these tend to form tubuloacinar structures and contain more retinal pigment epithelium-derived cells than tissue excised from cases with idiopathic macular pucker.
  
  
  CONCLUSIONS
  Patients with acute macular pucker have precipitous visual loss caused by epiretinal membrane formation after retinal tear or detachment. Early surgery in these patients results in rapid recovery of visual acuity and resolution of metamorphopsia. The clinical features and comparative immunohistochemistry suggest that acute macular pucker is a distinct clinicopathologic entity.
authors.affiliation: Moorfields Eye Hospital, London, England, UK.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Sheard
authors.forename: Charanjit
authors.initials: C
authors.lastname: Sethi
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Gregor
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D019773:Epiretinal Membrane / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000150:complications; D012167:Retinal Perforations / Q000150:complications; D012189:Retrospective Studies; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy