title: [Chemotherapy induced neurotoxicity].
abstract: Lately, the focus of chemotherapy has become not only treating cancer but also maintaining patients' quality of life. Drugs used in chemotherapy can cause damage and toxicity in normal cells as well as cancer cells. The degree of damage could cause dose limiting toxicity and may become one of the reasons of cessation of chemotherapy. Neurotoxicity causes numbness of hands and legs which may continue to cause patients' suffering for a long time after the treatment. At present, the cause of neurotoxicity induced by chemotherapy is not clear, but it is urgent to prevent, identify and treat as early as possible. Methods for symptom management to relieve such patients' suffering needs to be developed as soon as possible.
authors.affiliation: Department of Pain and Palliative Care, Chiba University Graduate School of Medicine.
authors.forename: Naohito
authors.initials: N
authors.lastname: Shimoyama
authors.forename: Hidenori
authors.initials: H
authors.lastname: Takahashi
authors.forename: Noboru
authors.initials: N
authors.lastname: Yamamoto
authors.forename: Megumi
authors.initials: M
authors.lastname: Simoyama
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents