[Sevofluran in pediatric practice--personal experience].
Sevofluran a new inhalational anesthetic is a preferred anesthetic agent for induction and maintenance of pediatric anesthesia because of its rapid induction, recovery characteristics and acceptable cardiovascular profile--now also accessible in Poland. Sevofluran isn't an ideal anesthetic, and the issue of postoperative excitement, potential nephrotoxicity requires clarification. This study was designed to compare the emergence characteristics of sevoflurane with halotane anaesthesia in paediatric patients having various surgical intervention. 102 children divided for subgroup of premedicated and nonpremedicated, underwent inhalation induction with nitrous oxide/oxygen and sevofluran or halotane. Incremental doses of either study drug were added until loss of eyelash reflex was achieved. We didn't use higher concentrations of sevoflurane than 5.5 Vol% and 3.5 Vol% for halothane. Sevoflurane patients has a greater incidence of emergence agitation.
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Oddział Anestezjologii i Intensywnej Terapii Uniwersyteckiego Szpitala Dzieciecego w Krakowie, Katedra Anestezjologii i Intensywnej Terapii Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
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D000293:Adolescent; D017109:Akathisia, Drug-Induced / Q000209:etiology; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D006221:Halothane / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008738:Methyl Ethers / Q000008:administration & dosage* / Q000009:adverse effects; D009609:Nitrous Oxide / Q000008:administration & dosage; D010372:Pediatrics / Q000379:methods; D011229:Preanesthetic Medication / Q000379:methods*; D000077149:Sevoflurane
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D009609:Nitrous Oxide; D006221:Halothane