Derivatives of 4-(2-hydroxylphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine.
In the structures of 2-(4-chlorophenyl)-4-(2-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine, C(21)H(16)ClNOS, 4-(2-hydroxyphenyl)-2-(4-tolyl)-2,3-dihydro-1,5-benzothiazepine, C(22)H(19)NOS, and 4-(2-hydroxyphenyl)-2-(3-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepine, C(22)H(19)NO(2)S, the central seven-membered heterocyclic rings adopt twist-boat conformations in which the N atoms are involved in strong intramolecular hydrogen bonds with the hydroxyl H atoms, resulting in six-membered rings.
Parvez
Masood
M
Department of Chemistry, The University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4. parvez@ucalgary.ca
Umbreen
Sumaira
S
Ansari
Farzana Latif
FL