title: [The skin and alopecia].
abstract: Adverse skin reactions to anti-tumor agents, can be classified either as general symptoms or as local symptoms. The former type of symptom can manifest as intoxication dermatosis; however, while its occurrence is rare, the symptom that requires the closest attention is toxic epidermal necrolysis, the outcome of which is death in most patients. The latter type of symptom includes extravasation of anti-tumor agents and alopecia. Treatment of extravasation induced skin disorders includes prompt and repeated local injections of steroids, while treatment of alopecia includes scalp cooling and external therapies.
authors.affiliation: Institute for the Analyses of Prognostic Factors in Skin Cancer.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Ishihara
mesh_terms: D000505:Alopecia / Q000139:chemically induced*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D012871:Skin Diseases / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents