title: Retrobulbar cellular schwannoma. Two cases report and review of the literature.
abstract: Cellular schwannoma is a variant of classical schwannoma that is characterized by high cellularity. As it is accompanied by mitotic figures, it is easily mistaken for a malignant neoplasm. However, hyalinized thick-walled blood vessels, an alternating growth pattern of spindle-shaped neoplastic cells, and even Verocay bodies can be found. It is most commonly seen in the paravertebral area, particularly in the mediastinum and retroperitoneum. Retrobulbar cellular schwannoma is uncommon, and only one case has been reported to date. In this study, we report two additional cases of retrobulbar cellular schwannoma that recurred two years after surgery. We suggest that the patient be given an aggressive postoperative treatment because a successful, complete excision cannot be guaranteed at such an anatomic site.
authors.affiliation: Department of Pathology, Chang Gung University, Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan, China.
authors.forename: Wan-Ting
authors.initials: WT
authors.lastname: Huang
authors.forename: Wei-Jen
authors.initials: WJ
authors.lastname: Chen
authors.forename: Huan-Chen
authors.initials: HC
authors.lastname: Hsu
authors.forename: Yu-Fen
authors.initials: YF
authors.lastname: Cheng
authors.forename: Hock-Liew
authors.initials: HL
authors.lastname: Eng
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D009918:Orbital Neoplasms / Q000473:pathology* / Q000601:surgery; D014786:Vision Disorders / Q000209:etiology