Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations.
We describe a case of spontaneous twin ectopic pregnancy, managed with the combination of local injection under ultrasound control and intramuscular administration of methotrexate. We describe a difference between the area under the curve of declining plasma concentration of methotrexate after intramuscular and local injection.
Fernandez
H
H
Department of Gynecology and Obstetrics, Hôpital Antoine Beclere, Clamart, France.
Bourget
P
P
Lelaidier
C
C
Doumerc
S
S
Frydman
R
R