title: HIV-2 subtype circulating in India (south).
abstract: The genetic types and subtypes of HIV vary from region to region. This study looked at the relative prevalence of HIV-2 subtypes in south India. Nucleotide sequencing of the HIV-2 envelope V3 region of strains from 11 individuals infected with HIV-2 and one individual who had dual infection with HIV-1 and HIV-2 was performed. Phylogenetic analysis showed that all individuals were infected with HIV-2 subtype A. These strains were from individuals who live in different regions of south India. In all, up to present, 17 strains inclusive of the authors' 12 have been sequenced, and subtype A of HIV-2 is seen in both monoinfections and dual infections with HIV-1 in India.
authors.affiliation: Department of Clinical Virology, Christian Medical College Hospital, Vellore-632 004, India.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Kannangai
authors.forename: Ramachandran V
authors.initials: RV
authors.lastname: Shaji
authors.forename: Sandeep
authors.initials: S
authors.lastname: Ramalingam
authors.forename: Mary V
authors.initials: MV
authors.lastname: Jesudason
authors.forename: Oriapadickal C
authors.initials: OC
authors.lastname: Abraham
authors.forename: Renu
authors.initials: R
authors.lastname: George
authors.forename: Arvindh P
authors.initials: AP
authors.lastname: Shanmugam
authors.forename: David H
authors.initials: DH
authors.lastname: Schwartz
authors.forename: Gopalan
authors.initials: G
authors.lastname: Sridharan
mesh_terms: D000328:Adult; D005260:Female; D015699:HIV Envelope Protein gp120 / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology*; D015498:HIV-2 / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics; D010802:Phylogeny
chemical_list: D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments