Immunohistochemistry in the diagnosis of soft tissue tumours.
Immunohistochemistry is particularly important in the field of soft tissue tumours because of their variety and the frequent difficulty of diagnosis. The first part of this paper discusses useful or new antibodies, together with others that are no longer of use. The second part is devoted to the role of immunohistochemistry in the diagnosis of soft tissue tumours: identification of some rare or atypical benign lesions, identification of non-mesenchymal malignant tumours, and classification of sarcomas. The respective roles of immunohistochemistry and molecular biology are underlined.
Coindre
J M
JM
Department of Pathology, Institut Bergonié and University Victor Segalen Bordeaux 2, 229 Cours de l'Argonne, 33076 Bordeaux cedex, France. coindre@bergonie.org
D000906:Antibodies / Q000737:chemistry; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D012509:Sarcoma / Q000737:chemistry / Q000145:classification / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000175:diagnosis*
D000906:Antibodies; D014408:Biomarkers, Tumor