Congenital dyserythropoietic anemia: clinical and hematological profile.
Congenital dyserythropoietic anemia (CDA) is a rare disorder, which manifests clinically with varying degrees of anemia and hepatosplenomegaly. These features are not pathognomic and a diagnosis of CDA is generally considered after other causes of chronic hemolytic anemia have been ruled out. The clinico-hematological profile of 10 patients with CDA is presented in this communication. Six patients had CDA type II and four had CDA type I. Age at onset of pallor ranged from birth to 9 years. Blood transfusion requirements varied from nil to monthly. This is the first report of CDA type I from India.
Marwaha
R K
RK
Division of Pediatric Hematology-Oncology, Advanced Pediatric Center, PGIMER, Chandigarh 160 012, India. rammarwaha1@rediffmail.com
Bansal
Deepak
D
Trehan
Amita
A
Garewal
Gurjeewan
G
Marwaha
Neelam
N
D000742:Anemia, Dyserythropoietic, Congenital / Q000097:blood / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017701:Reticulocyte Count
D005293:Ferritins