title: Pattern recognition methods in evaluation of the structure of the laboratory data biominerals, antioxidant enzymes, selected biochemical parameters, and pulmonary function of welders.
abstract: A wide set of biochemical and spirometrical parameters was applied to a group of 41 welders. The obtained parameters were analyzed by the pattern recognition method: principal-components analysis (PCA) and mutual contribution analysis (MCA). The aim of the investigation was to find out which of 23 parameters had an influence on the pulmonological indices of COPD. It was found that PCA gave a substantial reduction of dimensionality. The most relevant parameters were Fe, Zn, Cu (all elements in blood, not in hair), FEV1, MEF50, bilirubin, TAS, and SOD. Only the relationships of MEF50, Cu, and TAS were statistically valid.
authors.affiliation: Radioligand Laboratory of the Pharmacy Faculty, Collegium Medicum Jagiellonian University, 9 Medyczna str, 30-688 Kraków, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Stepniewski
authors.forename: Emilia
authors.initials: E
authors.lastname: Kolarzyk
authors.forename: Pawel
authors.initials: P
authors.lastname: Zagrodzki
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Solarska
authors.forename: Agata
authors.initials: A
authors.lastname: Pietrzycka
authors.forename: Mariusz
authors.initials: M
authors.lastname: Kitlinski
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Schlegel-Zawadzka
authors.forename: Bogdan
authors.initials: B
authors.lastname: Batko
mesh_terms: D000328:Adult; D000367:Age Factors; D000395:Air Pollutants, Occupational / Q000032:analysis / Q000097:blood; D000975:Antioxidants / Q000032:analysis*; D006197:Hair / Q000737:chemistry; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure; D018384:Oxidative Stress; D010363:Pattern Recognition, Automated; D025341:Principal Component Analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000097:blood* / Q000378:metabolism / Q000503:physiopathology*; D012129:Respiratory Function Tests; D013997:Time Factors; D014131:Trace Elements / Q000032:analysis* / Q000097:blood; D014896:Welding
chemical_list: D000395:Air Pollutants, Occupational; D000975:Antioxidants; D014131:Trace Elements