title: Effect of purified collagen on lipograft survival: experimental basis for periurethral lipoinjections.
abstract: OBJECTIVE
  To assess whether the use of collagens with lipografts improves graft survival.
  
  
  METHODS
  Thirty isogenic New Zealand rabbits were injected in the auricular area with either autologous fat alone or autologous fat associated with collagen. The animals were evaluated at 7, 30, and 90 days by histologic and morphometric methods together with measurements of the graft area and the number of adipocytes.
  
  
  RESULTS
  Addition of collagen to the lipoinjection reduced the local inflammatory reaction and improved the graft's survival; e.g., for stress urinary incontinence.
  
  
  CONCLUSIONS
  These results suggest that it is possible to increase the survival rate of the lipografts and improve their clinical applicability.
authors.affiliation: Department of Urology, Faculty of Medical Sciences, State University of Campinas, UNICAMP, Campinas, São Paulo, Brazil.
authors.forename: Paulo César Rodrigues
authors.initials: PC
authors.lastname: Palma
authors.forename: Benedicto
authors.initials: B
authors.lastname: Vidal
authors.forename: Cássio Luís Zanettini
authors.initials: CL
authors.lastname: Riccetto
authors.forename: Viviane
authors.initials: V
authors.lastname: Herrmann
authors.forename: Míriam
authors.initials: M
authors.lastname: Dambros
authors.forename: Marcelo
authors.initials: M
authors.lastname: Thiel
authors.forename: Nelson Rodrigues
authors.initials: NR
authors.lastname: Netto
mesh_terms: D017667:Adipocytes / Q000378:metabolism*; D000273:Adipose Tissue / Q000166:cytology / Q000378:metabolism / Q000637:transplantation*; D000818:Animals; D003094:Collagen / Q000008:administration & dosage*; D006085:Graft Survival; D007267:Injections; D015187:Lipectomy; D011817:Rabbits; D011897:Random Allocation
chemical_list: D003094:Collagen