title: SIC: A tool to detect short inverted segments in a biological sequence.
abstract: The web software SIC provides a tool to search for short inverted segments (length 3-5000 bp) in a DNA sequence. The sequence is assumed to follow a Markov model. A statistic which is sensitive to inversion is presented. Searching inverted segments is done by a scanning approach after the user specifies the size of the scanning window and the order of the Markov chain. A list of the highest score segments is given with an assessment of the randomness of the result. SIC can be accessed via the URL: http://stat.genopole.cnrs.fr/SIC/.
authors.affiliation: Laboratoire Statistique et Génome, Tour Evry 2, 91000 Evry, France. robelin@genopole.cnrs.fr
authors.forename: David
authors.initials: D
authors.lastname: Robelin
authors.forename: Hugues
authors.initials: H
authors.lastname: Richard
authors.forename: Bernard
authors.initials: B
authors.lastname: Prum
mesh_terms: D001483:Base Sequence; D003062:Codon; D020407:Internet; D008390:Markov Chains; D012091:Repetitive Sequences, Nucleic Acid; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
chemical_list: D003062:Codon