title: [Diagnosis and treatment in 45 patients with Hashimoto's thyroiditis associated with throat symptoms].
abstract: OBJECTIVE
  To assess the diagnosis and treatment in the patients complaining of throat discomfort that resulted from Hashimoto's thyroiditis (HT).
  
  
  METHODS
  Forty-five patients were reported for their clinical dates, 17 had abnormal sensation of pharynx, 5 stabbing feeling, 10 compressive feeling, 7 dry feeling, 6 sore throat. The pharyngeal symptoms were accompanied with hoarseness in 4. Thyroid uptake of 99mTc scan showed abnormal in 37 and normal in 8. Serum T3, T4 level was abnormal in 33 and normal in 12. Serum TSH level was abnormal in 26. Antithyroid antibodies estimated in 32 patients detected positive titers of TMAb and TGAb in 21 (66%) and in 18 (56%), respectively. Thirty were diagnosed as having HT by thyroid fine-needle aspiration biopsy (FNAB), 7 Hashimoto's hyperthyroidism. Tab. Thyroids were administrated to the patients at the period of euthyroidism or hypothyroidism and Propylthiouracilum to the ones at the period of hyperthyroidism.
  
  
  RESULTS
  Thirty-two patients received the follow-up for six months, throat symptoms disappeared in 27 and improved in 5.
  
  
  CONCLUSIONS
  Abnormal sensation of pharynx and hoarseness as well as sore throat play an important role in symptomatology of HT. Medicine therapy may make the patients with HT free of throat symptoms.
authors.affiliation: Department of Otolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006685:Hoarseness / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010612:Pharyngitis / Q000175:diagnosis / Q000188:drug therapy; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis* / Q000188:drug therapy