title: Central venous catheter occlusion and thrombosis.
abstract: Central venous catheters are widely used in children with critical illness and chronic disease. These devices are often essential in the delivery of medications and intravenous fluids and in hemodynamic monitoring. Central venous catheter occlusion and thrombosis are common problems in patients using these devices. This article reviews the background, pathophysiology, and incidence of catheter occlusion and catheter-related thrombosis. Diagnostic, preventive, and treatment strategies, along with future research directions, are addressed.
authors.affiliation: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Jacobs@cchmc.org
authors.forename: Brian R
authors.initials: BR
authors.lastname: Jacobs
mesh_terms: D002405:Catheterization, Central Venous / Q000009:adverse effects*; D004868:Equipment Failure; D006801:Humans; D010372:Pediatrics; D012307:Risk Factors; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control