title: Further efforts to predict pure-tone thresholds from distortion product otoacoustic emission input/output functions.
abstract: Recently, Boege and Janssen [J. Acoust. Soc. Am. 111, 1810-1818 (2002)] fit linear equations to distortion product otoacoustic emission (DPOAE) input/output (UO) functions after the DPOAE level (in dB SPL) was converted into pressure (in microPa). Significant correlations were observed between these DPOAE thresholds and audiometric thresholds. The present study extends their work by (1) evaluating the effect of frequency, (2) determining the behavioral thresholds in those conditions that did not meet inclusion criteria, and (3) including a wider range of stimulus levels. DPOAE I/O functions were measured in as many as 278 ears of subjects with normal and impaired hearing. Nine f2 frequencies (500 to 8000 Hz in 1/2-octave steps) were used, L2 ranged from 10 to 85 dB SPL (5-dB steps), and L1 was set according to the equation L1 = 0.4L2 + 39 dB [Kummer et al., J. Acoust. Soc. Am. 103, 3431-3444 (1998)] for L2 levels up to 65 dB SPL, beyond which L1 = L2. For the same conditions as those used by Boege and Janssen, we observed a frequency effect such that correlations were higher for mid-frequency threshold comparisons. In addition, a larger proportion of conditions not meeting inclusion criteria at mid and high frequencies had hearing losses exceeding 30 dB HL, compared to lower frequencies. These results suggest that DPOAE I/O functions can be used to predict audiometric thresholds with greater accuracy at mid and high frequencies, but only when certain inclusion criteria are met. When the SNR inclusion criterion is not met, the expected amount of hearing loss increases. Increasing the range of input levels from 20-65 dB SPL to 10-85 dB SPL increased the number of functions meeting inclusion criteria and increased the overall correlation between DPOAE and behavioral thresholds.
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA. gorga@boystown.org
authors.forename: Michael P
authors.initials: MP
authors.lastname: Gorga
authors.forename: Stephen T
authors.initials: ST
authors.lastname: Neely
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Dorn
authors.forename: Brenda M
authors.initials: BM
authors.lastname: Hoover
mesh_terms: D001301:Audiometry, Pure-Tone / Q000379:methods*; D001309:Auditory Threshold / Q000502:physiology*; D001489:Basilar Membrane / Q000503:physiopathology; D003054:Cochlear Implants; D003625:Data Collection / Q000706:statistics & numerical data; D018072:Hair Cells, Auditory, Outer / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008432:Mathematical Computing; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D010897:Pitch Discrimination / Q000502:physiology; D011237:Predictive Value of Tests; D012016:Reference Values; D012044:Regression Analysis; D012984:Software