title: [Asperger syndrome in childhood: review of four cases].
abstract: BACKGROUND
  Asperger syndrome is a pervasive developmental disorder included lately in the international classifications.
  
  
  METHODS
  We report the observations of four children presenting this syndrome. For every patient, we collected antecedents and psychomotor development; we made neuropsychological assessment and video recording. Three patients underwent an EEG and one a cerebral MRI.
  
  
  RESULTS
  These patients were between ten- and sixteen-year old. The neuropsychological assessment showed a heterogeneous intellectual functioning with three times out of four a dissociation between high verbal level and low non-verbal level. Their language appeared sophisticated, apragmatic, their comprehension was inflexible. The mean age at diagnosis was ten years. They showed a sociability and autonomy improvement but they were conscious of their difference and suffered from it.
  
  
  CONCLUSIONS
  Our four cases allow to present Asperger syndrome, slightly known in France. Collaborative studies and genetic studies are necessary to improve the knowledge of this syndrome.
authors.affiliation: Unité de neurologie pédiatrique, service de pédiatrie A, American Memorial Hospital, centre hospitalier universitaire de Reims, 47, rue Cognacq-Jay, 51092 Reims cedex, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Belkadi
authors.forename: F
authors.initials: F
authors.lastname: Gierski
authors.forename: C
authors.initials: C
authors.lastname: Clerc
authors.forename: V
authors.initials: V
authors.lastname: Bertot
authors.forename: C
authors.initials: C
authors.lastname: Brasselet
authors.forename: J
authors.initials: J
authors.lastname: Motte
mesh_terms: D000293:Adolescent; D020817:Asperger Syndrome / Q000150:complications / Q000473:pathology / Q000523:psychology*; D002648:Child; D005260:Female; D006801:Humans; D007360:Intelligence; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D012919:Social Behavior