Neuropsychiatric lupus syndromes: relationship with antiphospholipid antibodies.
The authors assessed the prevalence of neuropsychiatric manifestations occurring in patients with systemic lupus erythematosus (NPSLE), according to the American College of Rheumatology standardized definitions for NPSLE, and evaluated the relationship between NPSLE and antiphospholipid antibodies. Sixty-one consecutive SLE patients were studied. Neuropsychiatric manifestations consistent with the diagnosis of NPSLE occurred in 44 (72%). Patients with NPSLE showed significantly higher levels of anticardiolipin antibodies.
Afeltra
Antonella
A
University Campus Bio-Medico, Rome, Italy. a.afeltra@unicampus.it
Garzia
Pierluigi
P
Mitterhofer
Anna Paola
AP
Vadacca
Marta
M
Galluzzo
Sara
S
Del Porto
Flavia
F
Finamore
Licia
L
Pascucci
Stefano
S
Gasparini
Marina
M
Laganà
Bruno
B
Caccavo
Domenico
D
Ferri
Giovanni Maria
GM
Amoroso
Antonio
A
Francia
Ada
A
D000293:Adolescent; D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000097:blood; D017152:Antibodies, Antiphospholipid / Q000097:blood / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood; D004568:Electrodiagnosis; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007558:Italy / Q000453:epidemiology; D020945:Lupus Vasculitis, Central Nervous System / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D013577:Syndrome
D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M