title: [Comparison of the yearly cycle cosine curve imitative parameters of the clinical features of liver cancer at different longitude and latitude].
abstract: OBJECTIVE
  To explore whether there exists coincidence of the most appearing time of clinical features of liver cancer at different longitude and latitude, according to the law of field equation and the theory of warpage of space time by Einstein.
  
  
  METHODS
  Three regions with different longitude and latitude were selected randomly and sampled. There were 36 items altogether, including 12 clinical items, which were used to imitate the yearly cycle cosine curve. The acorphases and the ratioes of amplitudes and means were compared to justifying whether they were in the same range.
  
  
  RESULTS
  All the acorphases of 36 items appeared between -90.1degrees to -207.5 degrees (from april to july), existing in one third of the same range, in which 13 items occurred rhythmly (P<0.05). The image acorphases of liver cancer at the early and middle stage and gamma-glutamyl transpeptidase acorphase appeared between -98.5 degrees to -148.2 degrees (from april to may), in which 5 items occurred rhythmly (P<0.05).
  
  
  CONCLUSIONS
  It is the same mode of the yearly biologcal cycle for liver cancer malignant growth within the most appearing time (from april to july). It will increase the detecting rate of liver cancer at the early and middle stage during this time (especially from april to may).
authors.affiliation: Public Health School, Jiangxi Medical College, Nanchang 330006, China.
authors.forename: Wan-xian
authors.initials: WX
authors.lastname: Yu
authors.forename: Min-jing
authors.initials: MJ
authors.lastname: Zuo
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Wang
authors.forename: He-lang
authors.initials: HL
authors.lastname: Huang
authors.forename: Meng-li
authors.initials: ML
authors.lastname: Xie
authors.forename: Bao-chu
authors.initials: BC
authors.lastname: Zhang
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002453:Cell Cycle / Q000502:physiology*; D002909:Chronobiology Phenomena; D022781:Hepatocytes / Q000502:physiology; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008432:Mathematical Computing; D010507:Periodicity