title: [A case of sinonasal carcinoma with intracranial invasion treated by a multidisciplinary team].
abstract: We report a case of a 66-year-old male with diffuse infiltration of neoplasm from the paranasal sinuses to the orbit and left cerebral hemisphere, associated with prominent edema. Initial complaints were headache and swelling of the forehead, which were followed by progressive symptoms, such as epistaxis, dacryops, and severe pains. Neuroimaging showed marked invasion of a neoplasm from the left paranasal sinuses into the intracranial space and to the frontal skull. Radical removal of the neoplasm and left orbital content with reconstruction of the anterior skull base using musculocutaneous flap was carried out by a multidisciplinary team. The pathological diagnosis was "poorly differentiated carcinoma from the paranasal sinus". Postoperatively the patient received radiation and chemotherapy. He is still alive with mild right hemiparesis and mild dysphasia, more than 2 years after surgery.
authors.affiliation: Department of Neurosurgery, Sapporo Medical University, School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
authors.forename: Sounen
authors.initials: S
authors.lastname: Kin
authors.forename: Masahiko
authors.initials: M
authors.lastname: Wanibuchi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Minamida
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Yamaki
authors.forename: Sumiyoshi
authors.initials: S
authors.lastname: Tanabe
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Houkin
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology*; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D019292:Skull Base Neoplasms / Q000473:pathology