Ultrasound effect on the aromatic nucleophilic substitution reactions on some haloarenes.
The sonochemical nucleophilic aromatic substitutions on haloarenes with different amines have been studied. A beneficial ultrasound effect was observed and high yields of the products were obtained after 15-30 min sonication. The reaction course of the nucleophilic aromatic substitution was found to be strongly dependent on nucleophilicity, bulkiness, and boiling point of amines as well as on the electron-withdrawing property of the substituents on the haloarenes.
Meciarová
Mária
M
Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-2, SK-842 15 Bratislava, Slovak Republic. mmeciarova@fns.uniba.sk
Toma
Stefan
S
Magdolen
Peter
P