title: Combined phacoemulsification and pars plana vitrectomy: clear corneal versus scleral incisions: prospective randomized multicenter study.
abstract: OBJECTIVE
  To compare the complications and outcomes of implantation of a foldable intraocular lens (IOL) through a clear corneal incision and implantation of a poly(methyl methacrylate) (PMMA) IOL through a scleral incision in combined phacoemulsification and pars plana vitrectomy.
  
  
  METHODS
  Departments of Ophthalmology, St. Franziskus Hospital, Muenster, Eye Hospital, Muelheim, and University of Essen, Essen, Germany.
  
  
  METHODS
  This prospective randomized study included 62 eyes having implantation of a PMMA IOL (811B, Pharmacia) through a scleral incision and 61 eyes having implantation of a polyacrylic (AcrySof, Alcon) IOL through a clear corneal incision. The preoperative visual acuity, underlying retinal disease, and vitreoretinal surgical maneuvers did not differ between groups. The surgical methods and intraoperative complications were noted. Examinations 2 days and 3 months after surgery included visual acuity, refractive error, keratometry, slitlamp evaluation, tonometry, and ophthalmoscopy.
  
  
  RESULTS
  Intraoperatively, both incisions were stable and no serious complications occurred. Two days after surgery, the incidence and quantity of cells and fibrin in the anterior chamber were lower in the clear corneal incision group than in the scleral incision group (P<.05). Corneal endothelial dysfunction was more common in the clear corneal group than in the scleral group (P<.05). Three months after surgery, the astigmatic changes did not differ significantly between groups and the incidence of posterior capsule opacification (PCO) was lower in the clear corneal group (P<.05). Postoperative visual acuity improved significantly in 63% of eyes and 61% of eyes in the scleral group and clear corneal group, respectively. Visual acuity was limited by macular pathology.
  
  
  CONCLUSIONS
  Both clear corneal and scleral incisions were safe in combined phacoemulsification and vitrectomy. Eyes with smaller clear corneal incisions and foldable IOLs had less postoperative inflammation and PCO.
authors.affiliation: Department of Ophthalmology, St. Franziskus Hospital, Muenster, Germany. arnd.heiligesen@t-online.de
authors.forename: Arnd
authors.initials: A
authors.lastname: Heiligenhaus
authors.forename: Alexa
authors.initials: A
authors.lastname: Holtkamp
authors.forename: Jörg
authors.initials: J
authors.lastname: Koch
authors.forename: Harald
authors.initials: H
authors.lastname: Schilling
authors.forename: Norbert
authors.initials: N
authors.lastname: Bornfeld
authors.forename: Cay Christian
authors.initials: CC
authors.lastname: Lösche
authors.forename: Klaus Peter
authors.initials: KP
authors.lastname: Steuhl
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications / Q000628:therapy; D003315:Cornea / Q000601:surgery*; D005128:Eye Diseases / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular / Q000379:methods; D007910:Lenses, Intraocular; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D018918:Phacoemulsification / Q000379:methods*; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D011446:Prospective Studies; D012164:Retinal Diseases / Q000150:complications / Q000601:surgery; D012590:Sclera / Q000601:surgery*; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000473:pathology / Q000601:surgery
chemical_list: D019904:Polymethyl Methacrylate