Hemolytic uremic syndrome associated with group A beta-hemolytic streptococcus.
Group A beta-hemolytic streptococcal (GABS) hemorrhagic colitis due to Streptococcus pyogenes is extremely rare and its association with hemolytic uremic syndrome (HUS) in children has not been described. We report a 9-year-old white male who developed biopsy-proven HUS while continuing to have GABS-positive bloody diarrhea. Renal function deteriorated rapidly requiring intermittent hemodialysis. Three months following discharge, his renal function is normal for age except for significant proteinuria.
Shepherd
Amy B
AB
Department of Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA.
Palmer
April L
AL
Bigler
Steven A
SA
Baliga
Radhakrishna
R
D001706:Biopsy; D002648:Child; D003092:Colitis / Q000382:microbiology; D003967:Diarrhea / Q000382:microbiology; D006471:Gastrointestinal Hemorrhage / Q000382:microbiology; D006463:Hemolytic-Uremic Syndrome / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D008297:Male; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes