[Critical analysis of hypotheses explaining the increase in respiratory allergens].
There are three hypotheses to explain the relation between allergens and other factors and the onset of atopy: the hygiene hypothesis, the TH2 like hypothesis and the allergenic hypothesis. None of them have been confirmed. It seems necessary to wait for the results of prospective studies before giving recommendations for primary prevention of respiratory allergic diseases. In contrast, tertiary prevention appears as an essential method for treatment of allergic diseases.
De Blay
F
F
Service de Pneumologie, Hôpital Lyautey, Hôpitaux Universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg Cedex. frederic.deblay@chru-strasbourg.fr
Sohy
C
C
Casset
A
A
Birba
E
E
D000485:Allergens / Q000009:adverse effects*; D006801:Humans; D006920:Hygiene; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000503:physiopathology*; D012140:Respiratory Tract Diseases / Q000276:immunology* / Q000503:physiopathology*; D018418:Th2 Cells / Q000502:physiology
D000485:Allergens