Schinzel-Giedion syndrome with sacrococcygeal teratoma.
A case of Schinzel-Giedion syndrome, a rare malformation syndrome, is described. In addition to the classic features of the syndrome, the patient had a malignant sacrococcygeal teratoma and agenesis of the corpus callosum. So far, this patient is the fifth case with a sacrococcygeal tumor and the eighth with anomalies of the corpus callosum. According to this occurrence of uncommon tumors, risk of malignancy could be a component of Schinzel-Giedion syndrome.
Sandri
Alessandro
A
Divisione di Pediatria Oncologica, Università degli Studi di Torino, Piazza Polonia 94, 10100 Torino, Italy. alessandro.sandri@.unito.it.
Manazza
Andrea Domenco
AD
Bertin
Daniele
D
Silengo
Margherita
M
Basso
Maria Eleonora
ME
Forni
Marco
M
Madon
Enrico
E
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000473:pathology; D018240:Endodermal Sinus Tumor / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012445:Sacrococcygeal Region; D013724:Teratoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins