title: Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas.
abstract: Four hundred and eight clinical strains of Vibrio cholerae isolated from different geographical areas and with different antimicrobial resistance patterns were tested for susceptibility to rifaximin, a non-absorbable antibiotic active in vitro against Gram-negative bacteria. The MICs ranged from 0.5 to 4 mg/l for all strains. These values and the pharmacokinetic properties suggest rifaximin as an attractive antimicrobial agent for cholera.
authors.affiliation: Dipartimento di Anatomia Patologica e di Genetica, Sezione di Genetica, Università di Bari, Via G. Amendola 165/A, 70126 Bari, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Scrascia
authors.forename: Maria
authors.initials: M
authors.lastname: Forcillo
authors.forename: Francesco
authors.initials: F
authors.lastname: Maimone
authors.forename: Carlo
authors.initials: C
authors.lastname: Pazzani
mesh_terms: D000349:Africa; D002489:Central America; D024881:Drug Resistance, Bacterial / Q000502:physiology*; D005060:Europe; D006801:Humans; D008826:Microbial Sensitivity Tests; D012294:Rifamycins / Q000494:pharmacology*; D000078262:Rifaximin; D013020:South America; D014734:Vibrio cholerae / Q000187:drug effects* / Q000302:isolation & purification*
chemical_list: D012294:Rifamycins; D000078262:Rifaximin