title: Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?
authors.affiliation: The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
authors.forename: Ivan V
authors.initials: IV
authors.lastname: Litvinov
authors.forename: Angelo M
authors.initials: AM
authors.lastname: De Marzo
authors.forename: John T
authors.initials: JT
authors.lastname: Isaacs
mesh_terms: D002454:Cell Differentiation / Q000502:physiology; D015195:Drug Design; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology*; D011944:Receptors, Androgen / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D011944:Receptors, Androgen