title: Preparation of "high specific activity" radiochemical forms of vanadium, manganese and thallium for metallo-toxicological studies.
abstract: In this paper are presented the production methods for very "high specific activity" radionuclides (HSA-RN) of vanadium, manganese and thallium which have been developed in our laboratories for labelling different chemical forms of these elements present in the echo-systems in ultra-trace amounts, for metallo-toxicological and bio-kinetic studies. Use was made of both cyclotron and thermal nuclear reactor. If the nuclear reaction product has atomic number different from irradiated target, it is possible separating the radioactive nuclide from irradiated target, without addition of isotopic carrier. This kind of radionuclide is named No Carrier Added, NCA, and his specific activity, As is very high and can reach values close to the theoretical Carrier Free one, CF. The experimental determination of specific activity, chemical and radiochemical purities is mandatory for all these kinds of applications.
authors.affiliation: Radiochemistry Laboratory, LASA, Università degli Studi di Milano and National Institute of Nuclear Physics, INFN, Via F.lli Cervi 201,1-20090 Segrate, Milano, Italy. Mauro.Bonardi@MI.INFN.IT
authors.forename: Mauro
authors.initials: M
authors.lastname: Bonardi
authors.forename: Claudio
authors.initials: C
authors.lastname: Birattari
authors.forename: Flavia
authors.initials: F
authors.lastname: Groppi
authors.forename: Luigi
authors.initials: L
authors.lastname: Gini
authors.forename: Alberto
authors.initials: A
authors.lastname: Ghioni
authors.forename: Hae Song
authors.initials: HS
authors.lastname: Mainardi
authors.forename: Dolores
authors.initials: D
authors.lastname: Arginelli
authors.forename: Mario
authors.initials: M
authors.lastname: Gallorini
authors.forename: Enrico
authors.initials: E
authors.lastname: Rizzio
authors.forename: Enrico
authors.initials: E
authors.lastname: Sabbioni
mesh_terms: D017357:Cyclotrons; D008345:Manganese / Q000737:chemistry; D011849:Radioactive Tracers; D011868:Radioisotopes / Q000737:chemistry*; D011876:Radionuclide Generators; D013793:Thallium / Q000737:chemistry; D013794:Thallium Radioisotopes / Q000737:chemistry; D018675:Toxicity Tests; D014131:Trace Elements / Q000032:analysis*; D014639:Vanadium / Q000737:chemistry
chemical_list: D011849:Radioactive Tracers; D011868:Radioisotopes; D013794:Thallium Radioisotopes; D014131:Trace Elements; D014639:Vanadium; D008345:Manganese; D013793:Thallium