title: Age estimation in dental pulp DNA based on human telomere shortening.
abstract: Age estimation based on evidence found in teeth has received considerable attention within the field of forensic science. We determined the terminal restriction fragment (TRF) length, as telomere length, to estimate age. Using dental pulp DNA we found the average TRF length showed a tendency to shortening with aging. Our findings show that telomere shortening, based on dental pulp DNA is a new and useful approach to estimate age of the subject at the time of death.
authors.affiliation: Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Sciences Kyushu University, 812-8582, Fukuoka, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Takasaki
authors.forename: Akiko
authors.initials: A
authors.lastname: Tsuji
authors.forename: Noriaki
authors.initials: N
authors.lastname: Ikeda
authors.forename: Masamichi
authors.initials: M
authors.lastname: Ohishi
mesh_terms: D000375:Aging / Q000235:genetics / Q000502:physiology; D004247:DNA / Q000235:genetics*; D003782:Dental Pulp / Q000166:cytology*; D044707:Forensic Sciences; D006801:Humans; D007564:Japan; D016615:Telomere / Q000235:genetics / Q000502:physiology*
chemical_list: D004247:DNA