[Oocyte and embryo quality in polycystic ovary syndrome].
OBJECTIVE
To compare oocyte and embryo quality in women with Polycystic Ovary Syndrome (PCOS) and in women with normal ovulation.


METHODS
Forty women with PCOS underwent a total of 67 In Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) cycles. The control group consisted of women, of the same age, who underwent IVF (for tubal infertility) or ICSI (for male factor infertility) in the same period.


RESULTS
The average number of oocytes recovered was higher in the PCOS group (12,1) than in the control group (9.6) as was the rate of immature oocytes (13.8% vs 5.8%; respectively). The fertilization rate was lower in PCOS patients (52% vs 61% in the controls). The cleavage rates, embryo morphology and pregnancy rates were similar in both groups.


CONCLUSIONS
Although more oocytes were recovered from PCOS patients, the number of good quality embryos, suitable for transfer or freezing was similar in the two groups as less of the oocytes were mature and the fertilization rate was lower in the PCOS group. IVF or ICSI (according to the indication) are therefore efficient in PCOS patients.
Plachot
M
M
Laboratoire de fécondation in vitro, CHI Jean-Rostand, 141, Grande-rue, 92311 cedex, Sèvres, France. mplachot@promptomail.com <mplachot@promptomail.com>
Belaisch-Allart
J
J
Mayenga
J M
JM
Chouraqui
A
A
Tesquier
A
A
Serkine
A M
AM
Boujenah
A
A
Abirached
F
F
D002452:Cell Count; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D009865:Oocytes / Q000502:physiology*; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000503:physiopathology*; D011247:Pregnancy; D011786:Quality Control; D020554:Sperm Injections, Intracytoplasmic; D020858:Tissue and Organ Harvesting