title: [Enjoying research on lysozymes for 42 years].
abstract: I have pursued research on lysozymes for 42 years. During that time, I made Several new findings, some of them by chance. My enjoyment of the following areas is reviewed: the story of tryptophan; protease digestion mechanisms; peptide mapping with RP-HPLC; gene engineering; renaturation of protein; catalytic residues; fluctuation and function; stabilization; folding; antigenecity; tolerance; and various lysozymes.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Taiji
authors.initials: T
authors.lastname: Imoto
mesh_terms: D000818:Animals; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D010450:Endopeptidases; D049673:History, 20th Century; D006801:Humans; D007564:Japan; D009113:Muramidase / Q000737:chemistry / Q000266:history; D010449:Peptide Mapping / Q000379:methods; D015202:Protein Engineering; D017510:Protein Folding; D020673:Protein Renaturation; D011506:Proteins / Q000378:metabolism; D014364:Tryptophan
chemical_list: D011506:Proteins; D014364:Tryptophan; D009113:Muramidase; D010450:Endopeptidases