Riluzole, an inhibitor of glutamatergic transmission, suppresses levodopa-induced rotations in 6-hydroxydopamine-lesioned rats.
Gilgun-Sherki
Yossi
Y
Department of Neurology and Felsenstein Medical Research Center, Rabin Medical Center- Campus Beilinson, The Sackler Faculty of Medicine, Tel Aviv University, Petah-Tikva 49100, Israel.
Melamed
Eldad
E
Ziv
Ilan
I
Offen
Daniel
D
D000818:Animals; D000978:Antiparkinson Agents / Q000009:adverse effects*; D001058:Apomorphine / Q000009:adverse effects; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology*; D007980:Levodopa / Q000009:adverse effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D016627:Oxidopamine; D010302:Parkinson Disease, Secondary / Q000139:chemically induced / Q000378:metabolism / Q000523:psychology; D051381:Rats; D017207:Rats, Sprague-Dawley; D017470:Receptors, Glutamate / Q000187:drug effects* / Q000502:physiology; D019782:Riluzole / Q000494:pharmacology*; D009435:Synaptic Transmission / Q000187:drug effects
D000978:Antiparkinson Agents; D018691:Excitatory Amino Acid Antagonists; D017470:Receptors, Glutamate; D007980:Levodopa; D019782:Riluzole; D016627:Oxidopamine; D001058:Apomorphine