title: Dehydrative sialylation with C2-hemiketal sialyl donors.
abstract: [reaction: see text] A new method for sialylation involving the dehydrative coupling of sialyl donors with the reagent combination of (p-nitrophenyl)(phenyl) sulfoxide and triflic anhydride is reported. This process establishes sialyl C2-hemiketals as viable sialyl donors for complex carbohydrate synthesis.
authors.affiliation: Department of Chemistry, Roger Adams Laboratory, University of Illinois, Urbana, Illinois 61801, USA.
authors.forename: Jannine M
authors.initials: JM
authors.lastname: Haberman
authors.forename: David Y
authors.initials: DY
authors.lastname: Gin
mesh_terms: D019158:N-Acetylneuraminic Acid / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D019158:N-Acetylneuraminic Acid