title: Transjugular preoperative portal embolization (TJPE) a pilot study.
abstract: OBJECTIVE
  Because of our previous experience with transjugular intrahepatic portosystemic shunt, we decided to apply the transjugular approach to preoperative portal embolization. The aim of this pilot study was to determine the feasibility and the potential advantages and disadvantages of this new method.
  
  
  METHODS
  Under ultrasound guidance the right or left portal branch was punctured from the right, median or left hepatic vein. Then, a catheter was placed near the portal bifurcation and used to perform right portal branch embolization with a mixture of Histoacryl and Lipiodol. Pre- and post-transjugular preoperative portal embolization duplex ultrasound and CT scan were performed to assess portal flow and liver tissue growth. Hospital stay, pain and hepatic enzymes were monitored.
  
  
  RESULTS
  Fifteen patients underwent a transjugular preoperative portal embolization without any serious complication. Mean of hospital stay was 3.3 +/- 0.6 days. (2-5 days). Portal embolization was successful in all cases; left portal branch velocity increased from 11.8 +/- 7.5 cm/s before, to 16.5 +/- 3.5 cm/s on day one, and 14.8 +/- 3.3 cm/s on day 28 after transjugular preoperative portal embolization; volume of non-embolized segments increased by 10% within the 4 weeks after transjugular preoperative portal embolization. Right hepatectomy was possible in 12 patients
  
  
  CONCLUSIONS
  This method is safe, painless, and can be proposed in cases of impossibility to perform the standard percutaneous transhepatic portal embolization (tumor interposition, impaired hemostasis).
authors.affiliation: Unit of Interventional Hepatology and Surgery CHR, Metz, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Perarnau
authors.forename: Salam
authors.initials: S
authors.lastname: Daradkeh
authors.forename: Marc
authors.initials: M
authors.lastname: Johann
authors.forename: Michele
authors.initials: M
authors.lastname: Deneuville
authors.forename: Pierre
authors.initials: P
authors.lastname: Weinling
authors.forename: Claudine
authors.initials: C
authors.lastname: Coniel
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000628:therapy*; D002405:Catheterization, Central Venous / Q000379:methods*; D003131:Combined Modality Therapy; D018450:Disease Progression; D004621:Embolization, Therapeutic / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000098:blood supply / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010865:Pilot Projects; D011172:Portography; D011300:Preoperative Care