title: Latent tuberculosis in pregnancy: screening and treatment.
abstract: Currently, most cases of active tuberculosis in the United States are a result of activation of latent tuberculosis infection. In this article, the history of the epidemiology of tuberculosis and latent tuberculosis infection is reviewed. Previous and current recommendations for screening and treatment for latent tuberculosis during pregnancy and the postpartum period are discussed. A review of the literature regarding postpartum and antepartum treatment is included. Finally, the question of whether antepartum or postpartum treatment is the most beneficial is discussed.
authors.affiliation: Department of Obstetrics and Gynecology, Indian Chicano Health Center, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA. cgray@creighton.edu
authors.forename: Kimberly G
authors.initials: KG
authors.lastname: Bergeron
authors.forename: Robert G
authors.initials: RG
authors.lastname: Bonebrake
authors.forename: Courtney
authors.initials: C
authors.lastname: Allen
authors.forename: Caron J
authors.initials: CJ
authors.lastname: Gray
mesh_terms: D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use; D056487:Chemical and Drug Induced Liver Injury, Chronic / Q000209:etiology / Q000517:prevention & control; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use; D008403:Mass Screening / Q000379:methods; D010349:Patient Compliance / Q000706:statistics & numerical data; D049590:Postpartum Period; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D011296:Prenatal Diagnosis / Q000379:methods; D012293:Rifampin / Q000627:therapeutic use; D014376:Tuberculosis / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D014481:United States / Q000453:epidemiology; D028761:Withholding Treatment
chemical_list: D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin