Sample preparation, extraction efficiency, and determination of six arsenic species present in food composites.
Several sample preparation techniques were investigated to maximize the efficiency of arsenic species extraction from food composites. The optimized method includes lyophilization of food followed by prewashing with acetone and extraction by sonication with 50/50 methanol/water. Six arsenic species were separated and quantitated using an ammonium carbonate buffer system by ion exchange chromatography coupled to inductively coupled plasma mass spectrometry. The performance of the method for speciated arsenic components was evaluated using a matrix containing high fat food composite fortified with arsenic species. A certified reference material, dogfish muscle, was used to evaluate extraction methods for total arsenic content in food composites. More than 200 food composite samples were analyzed during an 18 month period, demonstrating the reliability of the analytical method over a long time period.
Milstein
Lisa S
LS
RTI International, 3040 Cornwallis Road, RTP, NC 27709-2194, USA. lmilstein@rti.org
Essader
Amal
A
Murrell
Carlynn
C
Pellizzari
Edo D
ED
Fernando
Reshan A
RA
Raymer
James H
JH
Akinbo
Olujide
O
D000096:Acetone; D001152:Arsenicals / Q000032:analysis*; D002852:Chromatography, Ion Exchange; D005504:Food Analysis / Q000379:methods*; D005612:Freeze Drying; D013058:Mass Spectrometry; D013010:Sonication
D001152:Arsenicals; D000096:Acetone