Medicine. The need for a global HIV vaccine enterprise.
A new collaborative model of research is needed to increase resources, to prioritize the R (ii) to increase the pace, reduce the overlap, and more systematically explore the elements of and delivery systems for vaccines; (iii) to use common standards for the prompt comparative testing of vaccine candidates; (iv) to expand resources for manufacturing vaccine candidates to speed their use in human trials; and (v) to increase the capacity for international clinical trials and to focus this effort toward quickly measuring the effectiveness of vaccine protection as prototype vaccine candidates are identified.
Klausner
Richard D
RD
Bill and Melinda Gates Foundation, Seattle, WA 98102, USA.
Fauci
Anthony S
AS
Corey
Lawrence
L
Nabel
Gary J
GJ
Gayle
Helene
H
Berkley
Seth
S
Haynes
Barton F
BF
Baltimore
David
D
Collins
Chris
C
Douglas
R Gordon
RG
Esparza
Jose
J
Francis
Donald P
DP
Ganguly
N K
NK
Gerberding
Julie Louise
JL
Johnston
Margaret I
MI
Kazatchkine
Michel D
MD
McMichael
Andrew J
AJ
Makgoba
Malegapuru W
MW
Pantaleo
Giuseppe
G
Piot
Peter
P
Shao
Yiming
Y
Tramont
Edmund
E
Varmus
Harold
H
Wasserheit
Judith N
JN
D016915:AIDS Vaccines / Q000008:administration & dosage / Q000191:economics / Q000276:immunology; D000047:Academies and Institutes / Q000191:economics / Q000458:organization & administration; D001709:Biotechnology / Q000191:economics; D002986:Clinical Trials as Topic / Q000592:standards; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000592:standards; D004345:Drug Industry / Q000191:economics; D005378:Financial Support; D014943:Global Health; D015658:HIV Infections / Q000517:prevention & control*; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D018973:Intellectual Property; D007391:International Cooperation; D015337:Multicenter Studies as Topic; D017149:Private Sector; D011640:Public Policy; D017150:Public Sector; D012109:Research Support as Topic; D014611:Vaccination
D016915:AIDS Vaccines