title: Mesalazine-associated benign intracranial hypertension in a patient with ulcerative colitis.
abstract: OBJECTIVE
  To report a case of benign intracranial hypertension related to mesalazine use.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  A 23-year-old-woman with sudden visual loss, headache, and a history of ulcerative colitis treated with mesalazine underwent ophthalmologic examination, echography, magnetic resonance imaging, and lumbar puncture.
  
  
  RESULTS
  The examinations disclosed benign intracranial hypertension that resolved when mesalazine was discontinued and recurred when the drug was restarted.
  
  
  CONCLUSIONS
  We recommend periodic ocular fundus examination for patients undergoing long-term therapy with mesalazine, especially if decreased vision, headaches, or neck stiffness are present, to avoid potentially severe complications of intracranial hypertension
authors.affiliation: Eye Department, 2nd University of Naples, Naples, Italy. nocola.rosa@unina2.it
authors.forename: Nicola
authors.initials: N
authors.lastname: Rosa
authors.forename: Arcangelo
authors.initials: A
authors.lastname: Giamundo
authors.forename: Attilio
authors.initials: A
authors.lastname: Jura
authors.forename: Gennarfrancesco
authors.initials: G
authors.lastname: Iaccarino
authors.forename: Antonio
authors.initials: A
authors.lastname: Romano
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D005260:Female; D006261:Headache / Q000139:chemically induced; D006801:Humans; D019804:Mesalamine / Q000009:adverse effects*; D009900:Optic Nerve / Q000000981:diagnostic imaging; D011559:Pseudotumor Cerebri / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014786:Vision Disorders / Q000139:chemically induced
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine