title: Production and resolution of cantharidin-induced inflammatory blisters.
abstract: While inflammatory blisters have long been utilized as a means of evaluating antimicrobial disposition to aid in the development of new treatments for skin and skin structure infections, sparse data are available regarding the healing of the blisters once the experiment has been completed. We report the blister induction technique and resolution time in ten volunteers enrolled in a pharmacokinetic study using the cantharidin-induced inflammatory blister technique.
authors.affiliation: Center for Anti-Injective Research and Development, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Maglio
authors.forename: Charles H
authors.initials: CH
authors.lastname: Nightingale
authors.forename: David P
authors.initials: DP
authors.lastname: Nicolau
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics; D001768:Blister / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology*; D002193:Cantharidin / Q000008:administration & dosage / Q000633:toxicity*; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology; D007509:Irritants / Q000008:administration & dosage* / Q000633:toxicity*; D012867:Skin / Q000378:metabolism / Q000473:pathology; D012880:Skin Pigmentation; D013997:Time Factors; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents; D007509:Irritants; D002193:Cantharidin