Mesothelioma: Drug treatment and other interventions.
Malignant mesothelioma was reported to be a tumor of the pleura for which there is no satisfactory treatment. It was also reported to be almost universally fatal, regardless of the stage of the tumor at the time of diagnosis. Due to the dismal prognosis for patients with this malignant disease, a new mode of treatment is desperately needed. Current drugs and other interventional modalities which include surgery, chemotherapy and radiation therapy are discussed below. However, in some patients none of these modalities are superior to absence of treatment. Discussed within this article are single agent and combined chemomodality therapy studies, target ligands, radiation-sensitizing and antiviral agents, multimodality and gene therapy, and chemoresistance.
Tomera
J F
JF