Radioimmunodetection of colorectal carcinoma.
OBJECTIVE
The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using 111In-labeled antibodies B72.3.


METHODS
Fourteen patients underwent planar immunoscintigraphy and/or tomoscintigraphy.


RESULTS
With tomography in comparison to planar scintigraphy, we can access better distinction of tumor and estimation of its size. Other imaging methods (computed tomography, ultrasonography) have an advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumors and extrahepatic metastases.


CONCLUSIONS
The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.
Artiko
V
V
Institute for Nuclear Medicine, Clinical Center of Serbia, Visegradska 26, 11 000 Belgrade, Yugoslavia.
Obradovic
V
V
Davidovic
B
B
Petrovic
N
N
Petrovic
M
M
Krivokapic
Z
Z
Kecmanovic
D
D
Pesko
P
P
Djukic
V
V
Milosavljevic
T
T
Adanja
G
G
Vlajkovic
M
M
D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D000911:Antibodies, Monoclonal; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007205:Indium Radioisotopes; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D009842:Oligopeptides; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D016719:Radioimmunodetection
D000911:Antibodies, Monoclonal; C063430:Indium 111In-satumomab pendetide; D007205:Indium Radioisotopes; D009842:Oligopeptides; D004369:Pentetic Acid