[The clinical evaluation of Oratest in detecting oral mucosal lesions].
OBJECTIVE
The aim of the study was to evaluate the clinical efficacy of Oratest in detecting oral mucosal lesions.


METHODS
Sixty patients with oral mucosal lesions that were suspected as carcinoma or premalignant lesions were divided into two groups randomly. The lesions were stained with Oratest by topical application in one group and rinse application in another group. Staining results were recorded and compared with the pathological diagnosis.


RESULTS
The sensitivity of Oratest stain to oral carcinoma and dysplasia were 93.9% and 42.9%, respectively. The difference between rinse application and local application showed no significance(P > 0.01).


CONCLUSIONS
Oratest can be used as a method of diagnosing squamous cell carcinoma of oral mucosa, but its reliability in screening oral pre-malignant lesions is still uncertain.
Cheng
Bin
B
College of Stomatology, Sun Yat-sen University, Guangzhou 510060, China.
Yang
Linglan
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D002648:Child; D004396:Coloring Agents; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis*; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*; D013194:Staining and Labeling; D014048:Tolonium Chloride
D004396:Coloring Agents; D014048:Tolonium Chloride