title: Biochemical indicator for evaluation of connective tissue abnormalities in Menkes' disease.
abstract: Metabolites of collagen metabolism were analyzed in patients with Menkes' disease. The urinary deoxypyridinoline level was significantly low in the patients with Menkes' disease, indicating that it is a good marker of lysyl oxidase activity, which is related to the connective tissue abnormalities.
authors.affiliation: Department of Pediatrics, Teikyo University School of Medicine, Tokyo Metropolitan Hachioji Children's Hospital, Ibaraki University, Tokyo, Japan. hkodama@med.teikyo-u.ac.jp
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kodama
authors.forename: Emi
authors.initials: E
authors.lastname: Sato
authors.forename: Yukisige
authors.initials: Y
authors.lastname: Yanagawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ozawa
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Kozuma
mesh_terms: D000596:Amino Acids / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D003240:Connective Tissue Diseases / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007223:Infant; D007706:Menkes Kinky Hair Syndrome / Q000150:complications*
chemical_list: D000596:Amino Acids; D015415:Biomarkers; C036020:deoxypyridinoline