An engineer's approach to the development of real anti-aging medicine.
In this Viewpoint, I list the various age-related molecular and cellular changes that are thought to limit mammalian life-span, and I outline a problem-solving approach to reversing these detrimental changes. This approach should help to prevent the development of these age-related changes into life-threatening pathologies and possibly, in due course, allow a large increase in healthy human life expectancy.
de Grey
Aubrey D N J
AD
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK. ag24@gen.cam.ac.uk
D000375:Aging / Q000502:physiology*; D005853:Geriatrics / Q000379:methods*; D006801:Humans