[Evaluation of effectiveness of intervention on risk factors for cerebrovascular disease in three cities of China].
OBJECTIVE
To evaluate the effects of community intervention on risk factors of cerebrovascular disease.


METHODS
With cluster sampling, 2,586 and 2,723 women and men aged 35 to 74 were selected randomly as intervention cohort and control cohort, respectively, from about 300 thousand community population in Beijing, Shanghai and Changsha, during 1997 to 2000. Their blood pressure, levels of blood lipid, body mass index (BMI) were measured and status of smoking and alcohol consumption were surveyed as indices of evaluation. Health education for smoking quit, alcohol consumption restriction and reinforced treatment for diabetic and hypertensive patients were implemented in the intervention communities. And, 2,544 and 2,533 persons in the two cohorts responded three years after intervention, and then all the indices mentioned above were measure again for them.


RESULTS
Average reduction in systolic blood pressure by 3.21 mm Hg and serum level of total cholesterol by 0.58 mmol/L was achieved in intervention cohort after intervention, but with 0.48 mmol/L increase in triglyceride. Average blood levels of both high density lipoprotein-cholesterol (HDL-C) and glucose increased in the two cohorts after intervention, but with 0.30 mmol/L net increase of blood glucose in control cohort. There was no significant difference in average increase of HDL-C between the two cohorts. BMI increased by 0.56 in control cohort, and no significant change in intervention cohort. Proportion of smoking decreased by 5.4% in men and 2.4% in women of intervention cohort, and no change in control cohort.


CONCLUSIONS
Level of risk factors for cerebrovascular disease reduced significantly with community intervention.
Liu
Yun-hai
YH
Neurological Institute, Xiangya Hospital, Central Southern University, Changsha 410008, China.
Yang
Qi-dong
QD
Zhu
Wen-bin
WB
Wang
Wen-zhi
WZ
Wu
Sheng-ping
SP
Hong
Zhen
Z
Xu
Hong-wei
HW
Zhou
Yan-hong
YH
Huang
Mao-sheng
MS
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D015992:Body Mass Index; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000517:prevention & control*; D015331:Cohort Studies; D003153:Community Health Services; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000178:diet therapy; D006973:Hypertension / Q000150:complications*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012494:Sampling Studies; D012907:Smoking / Q000009:adverse effects; D014504:Urban Health
D008055:Lipids