[Amyloidosis localized in the seminal vesicles: clinico-pathological review of 8 cases diagnosed in surgical specimens].
OBJECTIVE
Clinical and pathological study of eight cases of localized amyloidosis of the seminal vesicles. Review of the literature.


METHODS
Immunohistochemical and histochemical study in surgical specimens.


RESULTS
Two of the eight cases studied for amyloidosis in seminal vesicles, were obtained from radical prostatectomy specimens; patients had prior androgen deprivation therapy for two months. Four cases were obtained from radical cistoprostatectomy specimens because of urothelial carcinoma and the last two cases were diagnosed by transrectal prostatic needle biopsy which including a portion of seminal vesicle. Amyloidosis of seminal the vesicle is permanganate-sensitive; A-Amyloid, laminin, amyloid P protein and collagen IV negative.


CONCLUSIONS
Localized amyloidosis ot the seminal vesicle is not an unusual finding. The incidence increases with age. The histochemical and immunohistochemical features are different from other amyloid deposits.
Caballero Martínez
M Cristina
MC
Servicio de Anatomía Patológica, Hospital de Navarra, Pamplona, España.
Gómez Dorronsoro
M Luisa
ML
Cuesta Alcalá
José Angel
JA
Amat Villegas
Irene
I
Beloqui Pérez
Raquel
R
Martínez Peñuela
José M
JM
Monzón Muñoz
Francisco José
FJ
D000230:Adenocarcinoma / Q000150:complications / Q000601:surgery; D000367:Age Factors; D000368:Aged; D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D015415:Biomarkers / Q000032:analysis; D001707:Biopsy, Needle; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000601:surgery; D003224:Congo Red; D015653:Cystectomy; D005832:Genital Diseases, Male / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000150:complications / Q000601:surgery; D012669:Seminal Vesicles / Q000473:pathology*; D013194:Staining and Labeling; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000601:surgery
D000682:Amyloid; D015415:Biomarkers; D003224:Congo Red