title: Mortality and recovery after stroke in the Gambia.
abstract: OBJECTIVE
  There are no previously published studies of the long-term outcome of stroke in sub-Saharan Africa. Our goal was to determine the case fatality, time to and cause of death, and recovery in a hospital cohort of stroke patients in The Gambia.
  
  
  METHODS
  For 1 year beginning April 1, 1990, any patient presenting to the Royal Victoria Hospital (Banjul) with a diagnosis of stroke or having a stroke as an inpatient was recruited. After a standardized assessment, patients were followed up at 1 month, 6 months, and 3 to 4 years to assess recovery or, for those who died, record the date and likely cause of death.
  
  
  RESULTS
  Mean age of the 106 patients (70 men) was 58 years (range, 20 to 93 years). By 1 and 6 months, 29 (27%) and 47 (44%), respectively, had died, with only 27 (25%) surviving to final follow-up (4 patients not traced). Death occurred in hospital in 43 patients (57%). Cause of death was the initial stroke in 46 (61%), further stroke in 5 (7%), infection in 9 (12%), miscellaneous in 8 (11%) (only 1 vascular), and unknown in 7 (9%). On Cox regression analysis, incontinence in the first 24 hours, sensory inattention, and impaired gag reflex on admission were significant predictors of mortality. Predictors of recovery were similar to those of developed countries.
  
  
  CONCLUSIONS
  Despite the young mean age, there was a high case fatality rate. The main cause of death was the stroke itself, and ischemic heart disease was very rare.
authors.affiliation: Department of Medicine, North Tyneside General Hospital, Tyne and Wear, UK. Richard.Walker@northumbria-healthcare.nhs.uk
authors.forename: Richard W
authors.initials: RW
authors.lastname: Walker
authors.forename: Michael
authors.initials: M
authors.lastname: Rolfe
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Kelly
authors.forename: Melville O
authors.initials: MO
authors.lastname: George
authors.forename: Oliver F W
authors.initials: OF
authors.lastname: James
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D005714:Gambia / Q000453:epidemiology; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D020127:Recovery of Function; D020521:Stroke / Q000175:diagnosis / Q000401:mortality*; D015996:Survival Rate