Presence of the Tet M determinant in a clinical isolate of Acinetobacter baumannii.
The tet(M) gene encodes a protein which is related to tetracycline ribosomal protection, one of the mechanisms of tetracycline resistance. A tet(M) gene that is 100% homologous to the tet(M) gene of Staphylococcus aureus has been found in a clinical isolate of Acinetobacter baumannii, which also carries the tet(A) gene encoding a tetracycline efflux pump.
Ribera
Anna
A
Servei de Microbiologia, Institut Clinic Infeccions i Immunologia, IDIBAPS, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, 08036 Barcelona, Spain.
Ruiz
Joaquim
J
Vila
Jordi
J
D000150:Acinetobacter / Q000187:drug effects / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D005798:Genes, Bacterial; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000494:pharmacology; D008969:Molecular Sequence Data; D013211:Staphylococcus aureus / Q000235:genetics; D013752:Tetracycline / Q000494:pharmacology; D013753:Tetracycline Resistance / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C083138:Tet M resistance protein, Bacteria; D013752:Tetracycline; D008911:Minocycline