title: Medicinal chemistry--first Anglo-Swedish symposium. 23-26 March, 2003, Are Fjällby, Sweden.
abstract: The first Anglo-Swedish Medicinal Chemistry Symposium was held in Are Fjallby, Sweden. It was well attended, with the majority of participants being medicinal chemists from the pharmaceutical industry. The meeting covered a wide range of topics and concentrated on the discovery, optimization and pharmacological profile of novel drugs for the treatment of a variety of diseases, including stroke, type 2 diabetes and cancer. In many of the presentations, emphasis was placed on the need for improvement in the physicokinetic profiles of potential drugs, in order that they reach late-stage clinical trials. This report covers the development of various kinases including glycogen synthase kinase-3 (GSK-3), cyclin-dependent kinase (CDK2), IkappaB and protease inhibitors, and antagonists for N-methyl-D-aspartate (NMDA) receptors.
authors.affiliation: BioFocus Discovery Ltd, Sittingbourne Research Centre, UK. clauret@biofocus.com
authors.forename: Christelle
authors.initials: C
authors.lastname: Lauret
mesh_terms: D000818:Animals; D002626:Chemistry, Pharmaceutical / Q000379:methods* / Q000639:trends; D004739:England; D006801:Humans; D013548:Sweden