Recent developments in linker design and application.
The linker connecting the solid support and the substrate is critical to the ultimate success of a solid-phase synthesis. The evolution of linker constructs continues, offering new approaches to the analysis, release and deconvolution of resin-bound material and allowing entry to new structural motifs.
Wills
A Jonathan
AJ
University Chemistry Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Balasubramanian
Shankar
S
D020650:Combinatorial Chemistry Techniques / Q000379:methods / Q000639:trends*; D015195:Drug Design; D007202:Indicators and Reagents; D013237:Stereoisomerism
D007202:Indicators and Reagents