Pemphigus vulgaris mimicking Paget's disease of the breast.
We report the development of an ulcerative skin lesion involving the areola of a 37-year-old woman. Clinically the lesion was compatible with Paget's disease, however, histologic evaluation identified pemphigus vulgaris. Differences in the presentation and treatment of these two entities are highlighted. The underlying role of plasminogen activator in the molecular pathology of both diseases is discussed.
Guyton
Daniel P
DP
Department of Surgery, Akron General Medical Center, Akron, Ohio 44307, USA. dguyton@agmc.org
Sloan Stakleff
Kimberly
K
Regula
Eric
E
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010144:Paget's Disease, Mammary / Q000175:diagnosis* / Q000473:pathology; D010392:Pemphigus / Q000175:diagnosis* / Q000473:pathology