Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.
The new nematicidal compound, betagamma-dehydrocurvularin (1), together with three known compounds, alphabeta-dehydrocurvularin (2), 8-beta-hydroxy-7-oxocurvularin (3) and 7-oxocurvularin (4), were isolated from the culture filtrate and mycelial mats of Aspergillus sp. The structures of 1-4 were established by spectroscopic methods including 2D NMR. The biological activities of 1-4 were examined by bioassays with root-lesion nematodes, and lettuce and rice seedlings.
Kusano
Miyako
M
Umea Plant Science Centre, Department of Forest Genetics and Plant Physiology, The Swedish University of Agricultural Sciences, SE 901 83 Umea, Sweden.
Nakagami
Kazumi
K
Fujioka
Shozo
S
Kawano
Tsuyoshi
T
Shimada
Atsumi
A
Kimura
Yasuo
Y
D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D010935:Plant Diseases / Q000469:parasitology; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D036226:Seedlings / Q000187:drug effects; D013057:Spectrum Analysis; D014431:Tylenchoidea / Q000187:drug effects*; D015025:Zearalenone / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology*
D000969:Antinematodal Agents; D015025:Zearalenone; C013455:curvularin