title: Understanding the effects of the polymer support on reaction rates and kinetics: knowledge toward efficient synthetic design.
abstract: Solid-phase organic synthesis (SPOS) has an ever-expanding role in the field of organic synthesis. Partially out of difficulty, and partially from the rapid speed of progress, few basic studies on the role of the physical structure of the resin have been undertaken, and the dissemination of the existing knowledge has been slow. Major advances have been made in the understanding of the many factors that govern a SPOS reaction's performance as a function of the choice of solid support.
authors.affiliation: Department of Chemistry, New York University, 29 Washington Place, Brown Building, Room 564, New York, NY 10003, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Walsh
authors.forename: Daqian
authors.initials: D
authors.lastname: Wu
authors.forename: Young-Tae
authors.initials: YT
authors.lastname: Chang
mesh_terms: D000577:Amides / Q000737:chemistry; D015195:Drug Design; D005456:Fluorescent Dyes; D007700:Kinetics; D011108:Polymers / Q000737:chemistry*
chemical_list: D000577:Amides; D005456:Fluorescent Dyes; D011108:Polymers