title: Sino-atrial block during anesthesia in a patient with breast cancer being treated with the anticancer drug epirubicin.
abstract: Epirubicin, an anticancer drug, causes cardiotoxicity. We reported a case of sino-atrial block during general anesthesia in a woman with breast cancer who had received epirubicin. Anesthesiologists should be aware of the possible occurrence of sino-atrial block with epirubicin, and planting a pacemaker might be considered even in asymptomatic patients.
authors.affiliation: Department of Anesthesiology, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Okamoto
authors.forename: Junichi
authors.initials: J
authors.lastname: Ogata
authors.forename: Kouichiro
authors.initials: K
authors.lastname: Minami
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects*; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D004562:Electrocardiography; D015251:Epirubicin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D010138:Pacemaker, Artificial; D012848:Sinoatrial Block / Q000209:etiology*
chemical_list: D000903:Antibiotics, Antineoplastic; D015251:Epirubicin