title: B-alkyl suzuki-miyaura cross-coupling reactions with air-stable potassium alkyltrifluoroborates.
abstract: The palladium-catalyzed cross-coupling reaction of substituted potassium alkyltrifluoroborates with aryl halides and aryl triflates proceeds readily with moderate to good yields. The potassium alkyltrifluoroborates 1, 2, and 3a-e were easily synthesized and obtained as air-stable crystalline solids that can be stored for long periods of time. All of the cross-couplings proceed under the same reaction conditions using PdCl(2)(dppf).CH(2)Cl(2) as catalyst in THF-H(2)O in the presence of 3 equiv of Cs(2)CO(3) as base.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA. gmolandr@sas.upenn.edu
authors.forename: Gary A
authors.initials: GA
authors.lastname: Molander
authors.forename: Chang-Soo
authors.initials: CS
authors.lastname: Yun
authors.forename: María
authors.initials: M
authors.lastname: Ribagorda
authors.forename: Betina
authors.initials: B
authors.lastname: Biolatto