Endometrial cancer in Asian migrants to the United States and their descendants.
OBJECTIVE
The purpose of this study was to determine the extent to which the incidence of endometrial cancer in Chinese, Japanese, and Filipino residents of the United States varies according to country of birth.


METHODS
Women 35-74 years diagnosed with endometrial cancer between 1973 and 1986 among residents of the San Francisco/Oakland (CA) metropolitan area, 13 counties of western Washington, and the state of Hawaii were identified by cancer registries serving these populations. From a special tabulation of the 1980 US census, we estimated the size of the population at risk in each of these three areas according to age, race, and country of birth.


RESULTS
The annual incidence of primary endometrial cancer was lower among Chinese-American (42.6/100,000) and Japanese-American (25.3/100,000) women born in Asia than among their counterparts who were born in the United States (57.2/100,000 and 51.2/100,000, respectively). No difference in incidence was observed between Filipino women born in Asia (27.4/100,000) and those born in the United States (25.4/100,000). The rate of endometrial cancer among US-born white women (77.0/100,000 women years) exceeded that in any of these Asian-American subgroups.


CONCLUSIONS
These findings suggest that some clues to the aetiologies of endometrial cancer may be found in exposures whose prevalence differs between generations of Chinese and Japanese Americans.
Liao
C Katherine
CK
University of Illinois at Urbana Champaign, Champaign IL 61820, USA.
Rosenblatt
Karin A
KA
Schwartz
Stephen M
SM
Weiss
Noel S
NS
D000328:Adult; D000368:Aged; D001213:Asian; D044466:Asian People; D002681:China / Q000208:ethnology; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000208:ethnology* / Q000235:genetics; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000208:ethnology; D008875:Middle Aged; D010679:Philippines / Q000208:ethnology; D014171:Transients and Migrants / Q000706:statistics & numerical data*; D014481:United States; D044465:White People