Novel carotenoids genetically engineered in a heterologous host.
Carotenoids are commercially important pigments that are essential for human health. Diverse carotenoids have been identified, but availability has impeded evaluation of their pharmaceutical potential. Molecular techniques have been developed to produce specific and novel carotenoids with improved biological activities.
Sandmann
Gerhard
G
Biosynthesis Group, Botanical Institute, J.W. Goethe Universität Frankfurt, P.O. Box 111932, D-60054, Frankfurt, Germany.
D002338:Carotenoids / Q000096:biosynthesis* / Q000235:genetics; D020650:Combinatorial Chemistry Techniques; D032621:DNA Shuffling; D004885:Erwinia / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005818:Genetic Engineering; D019753:Intramolecular Lyases / Q000378:metabolism; D013379:Substrate Specificity; D014170:Transformation, Genetic
D002338:Carotenoids; D019753:Intramolecular Lyases; C070925:lycopene cyclase-isomerase