Using diazepam and atropine before strabismus surgery to prevent postoperative nausea and vomiting: a randomized, controlled study.
OBJECTIVE
To evaluate the efficacy of diazepam and atropine sulfate premedication in preventing nausea and vomiting after strabismus surgery under general anesthesia.


METHODS
Fifty children age 4 to 15 years who underwent strabismus surgery at Cukurova University Medical Faculty, Department of Ophthalmology, from February 2000 to June 2000 were randomized into 2 groups: 25 children in the control group did not receive premedication, whereas 25 children in the treatment group received premedication with 0.15 mg/kg diazepam and 0.015 mg/kg atropine sulfate. Occurrence of postoperative nausea and vomiting (PONV) was recorded.


RESULTS
The incidence of PONV was lower in the premedicated group (P <.018, chi(2) test).


CONCLUSIONS
It is concluded that diazepam and atropine sulfate premedication decreases nausea and vomiting after strabismus surgery.
Ozcan
Altan A
AA
Department of Ophthalmology, Cukurova University Faculty of Medicine, Adana, Turkey.
Güneş
Yasemin
Y
Haciyakupoğlu
Gülhanim
G
D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use*; D002648:Child; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D003975:Diazepam / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009325:Nausea / Q000517:prevention & control*; D011184:Postoperative Period; D011300:Preoperative Care; D013285:Strabismus / Q000601:surgery*; D016896:Treatment Outcome; D014839:Vomiting / Q000517:prevention & control*
D014151:Anti-Anxiety Agents; D018680:Cholinergic Antagonists; D001285:Atropine; D003975:Diazepam