HIV-1 pathogenesis.
Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1 infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains elusive. A deeper understanding of the interplay between HIV-1 and its host and why simian immunodeficiency virus (SIV) is nonpathogenic in some natural hosts may provide a few answers.
Stevenson
Mario
M
Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Biotech 2, Suite 319, Worcester, Massachusetts 01605, USA. Mario.Stevenson@umassmed.edu
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000821:virology*; D003713:Dendritic Cells / Q000821:virology; D015658:HIV Infections / Q000473:pathology / Q000821:virology; D015497:HIV-1 / Q000472:pathogenicity* / Q000502:physiology; D006790:Host-Parasite Interactions; D006801:Humans; D008264:Macrophages / Q000821:virology; D015302:Simian Immunodeficiency Virus / Q000472:pathogenicity; D014779:Virus Replication / Q000502:physiology*