title: [Association of HLA-DPB1 alleles with chronic myelogenous leukemia in southern Chinese Hans].
abstract: To clarify the association between HLA-DPB1 alleles and chronic myelogenous leukemia (CML) in South Chinese, the allelic types of HLA-DPB1 were detected by sequence based typing (SBT) in 86 patients with CML and 82 healthy individuals from Southern China. The results showed that the frequencies of HLA-DPB1 * 1301 and DPB1 * 20011 were higher in patients with CML in comparison with those of healthy individuals. It is concluded that positive association may exist between certain HLA-DPB1 alleles and CML.
authors.affiliation: Department of Hematology, Nanfang Hospital, The First Military Medical University, Guangzhou, 510515, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Tian
authors.forename: Shu-Yun
authors.initials: SY
authors.lastname: Zhou
authors.forename: Ze-Huan
authors.initials: ZH
authors.lastname: Liu
authors.forename: Yong-Gui
authors.initials: YG
authors.lastname: Fu
authors.forename: Feng-Juan
authors.initials: FJ
authors.lastname: Lu
authors.forename: Jiang-Hai
authors.initials: JH
authors.lastname: Lin
authors.forename: An-Long
authors.initials: AL
authors.lastname: Xu
mesh_terms: D000483:Alleles; D016009:Chi-Square Distribution; D002681:China; D005787:Gene Frequency; D005838:Genotype; D006682:HLA-DP Antigens / Q000235:genetics*; D059868:HLA-DP beta-Chains; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics*
chemical_list: D006682:HLA-DP Antigens; D059868:HLA-DP beta-Chains; C071170:HLA-DPB1 antigen