title: [Psychological, immunological, and endocrinological implications of atopic dermatitis].
abstract: BACKGROUND
  The atopic dermatitis is a chronic disease with immunological alterations, neuro-immune-endocrine implications and repercussions in the psyche.
  
  
  OBJECTIVE
  To determine the effectiveness of the use of psychological support in the treatment of atopic dermatitis.
  
  
  METHODS
  This study included 20 patients (from 15 to 50 years old) with moderated and severe atopic dermatitis based on the Hanifin and Rafka modified criteria. They were classified in three groups of treatment: A) 10 patients with transfer factor and psychological support, B) 10 with transference factor without psychological support, C) 10 healthy individuals as a control group. At the beginning and ending of the analysis the degree of severity of the illness was determined using the SCORAD scale.
  
  
  RESULTS
  There was a more statistically significant clinical improvement on group A than in group B, besides a decrease in anxiety and depression, at a laboratory level including hormonal behavior, without meaningful changes.
  
  
  CONCLUSIONS
  It was demonstrated that the treatment with immune-modulator and psychological support on the moderated and severe atopic dermatitis improves the clinical and immunological evolution of this illness.
authors.affiliation: Departamento de Alergia e Inmunología Clínica, Hospital Lic. Adolfo López Mateos, ISSSTE, Avenida Universidad 132, Col. Florida, CP 01414, México, DF. claud_bp@yahoo.com
authors.forename: Claudia
authors.initials: C
authors.lastname: Beltrán de Paz
authors.forename: Graciela
authors.initials: G
authors.lastname: Flores Sandoval
authors.forename: Modesto
authors.initials: M
authors.lastname: Orea Solano
authors.forename: Javier
authors.initials: J
authors.lastname: Gómez Vera
authors.forename: Ernestina
authors.initials: E
authors.lastname: Serrano Miranda
authors.forename: Patricia
authors.initials: P
authors.lastname: Sevilla Flores
authors.forename: Yurhixy
authors.initials: Y
authors.lastname: Juárez Rojas
authors.forename: Sergio
authors.initials: S
authors.lastname: Estrada Parra
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D017209:Apoptosis; D003131:Combined Modality Therapy; D003876:Dermatitis, Atopic / Q000276:immunology / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology; D007073:Immunoglobulin E / Q000097:blood; D007958:Leukocyte Count; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011598:Psychoneuroimmunology; D011613:Psychotherapy; D012720:Severity of Illness Index; D012944:Social Support; D014165:Transfer Factor / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D014165:Transfer Factor; D007073:Immunoglobulin E