Tools for comparative protein structure modeling and analysis.
The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.
Eswar
Narayanan
N
Department of Biopharmaceutical Sciences and California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94143-2240, USA.
John
Bino
B
Mirkovic
Nebojsa
N
Fiser
Andras
A
Ilyin
Valentin A
VA
Pieper
Ursula
U
Stuart
Ashley C
AC
Marti-Renom
Marc A
MA
Madhusudhan
M S
MS
Yerkovich
Bozidar
B
Sali
Andrej
A
D020407:Internet; D008958:Models, Molecular; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry; D015203:Reproducibility of Results; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012984:Software; D040681:Structural Homology, Protein; D018511:Systems Integration
D011506:Proteins