title: A reported case involving impaired driving following self-administration of xylazine.
abstract: A case of suspected drug-impaired driving involving self-administration of xylazine (Xyla-Ject), a veterinary tranquilizing agent, and paroxetine is presented. Qualitative and quantitative analysis of xylazine and paroxetine were performed by gas chromatography with a flame-ionization detector (GC-FID) and gas chromatography/mass spectrometry (GC/MS). Whole blood xylazine and paroxetine concentrations were 0.57 and 0.02 microg/ml, respectively.
authors.affiliation: Toxicology Unit, Oklahoma State Bureau of Investigation, 2132 NE, 36th Street, Oklahoma City, OK 73111, USA. matts@osbi.state.ok.us
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Stillwell
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood / Q000737:chemistry; D000328:Adult; D001334:Automobile Driving; D006801:Humans; D008297:Male; D015394:Molecular Structure; D017374:Paroxetine / Q000008:administration & dosage / Q000009:adverse effects / Q000097:blood; D011597:Psychomotor Performance / Q000187:drug effects*; D012651:Self Medication; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000097:blood; D014991:Xylazine / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood / Q000737:chemistry
chemical_list: D000316:Adrenergic alpha-Agonists; D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors; D014991:Xylazine