title: Tools for comparative protein structure modeling and analysis.
abstract: The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.
authors.affiliation: Department of Biopharmaceutical Sciences and California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94143-2240, USA.
authors.forename: Narayanan
authors.initials: N
authors.lastname: Eswar
authors.forename: Bino
authors.initials: B
authors.lastname: John
authors.forename: Nebojsa
authors.initials: N
authors.lastname: Mirkovic
authors.forename: Andras
authors.initials: A
authors.lastname: Fiser
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Ilyin
authors.forename: Ursula
authors.initials: U
authors.lastname: Pieper
authors.forename: Ashley C
authors.initials: AC
authors.lastname: Stuart
authors.forename: Marc A
authors.initials: MA
authors.lastname: Marti-Renom
authors.forename: M S
authors.initials: MS
authors.lastname: Madhusudhan
authors.forename: Bozidar
authors.initials: B
authors.lastname: Yerkovich
authors.forename: Andrej
authors.initials: A
authors.lastname: Sali
mesh_terms: D020407:Internet; D008958:Models, Molecular; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry; D015203:Reproducibility of Results; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012984:Software; D040681:Structural Homology, Protein; D018511:Systems Integration
chemical_list: D011506:Proteins