title: Novel antibody switching defects in human patients.
authors.affiliation: The Children's Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Manis
authors.forename: Frederick W
authors.initials: FW
authors.lastname: Alt
mesh_terms: D003564:Cytidine Deaminase / Q000235:genetics / Q000378:metabolism; D015321:Gene Rearrangement; D005803:Genes, Immunoglobulin; D006801:Humans; D006942:Hypergammaglobulinemia / Q000235:genetics*; D017578:Immunoglobulin Class Switching / Q000235:genetics*; D007127:Immunoglobulin Constant Regions / Q000235:genetics; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D007075:Immunoglobulin M / Q000097:blood*; D011995:Recombination, Genetic; D027041:Somatic Hypermutation, Immunoglobulin; D013577:Syndrome; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
chemical_list: D007127:Immunoglobulin Constant Regions; D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D000098830:AICDA (Activation-Induced Cytidine Deaminase); D003564:Cytidine Deaminase