title: Opsoclonus: an early sign of neonatal herpes encephalitis.
abstract: Preferential involvement of certain central nervous systems areas by specific viruses provides a valuable guide to the selection of antiviral agents. We report a neonate that developed opsoclonus 7 days prior to the diagnosis of herpes simplex type 2 cerebellitis. The course of the opsoclonus paralleled the clinical course and radiologic evolution of the infection. The purpose of this report is to describe opsoclonus as a possible early sign of herpes simplex type 2 central nervous system infection.
authors.affiliation: Department of Neurology, Cleveland Clinic, Weston, Florida, USA.
authors.forename: Stanley
authors.initials: S
authors.lastname: Krolczyk
authors.forename: Esperanza
authors.initials: E
authors.lastname: Pacheco
authors.forename: Pablo
authors.initials: P
authors.lastname: Valencia
authors.forename: Oscar
authors.initials: O
authors.lastname: Papazian
authors.forename: Karina
authors.initials: K
authors.lastname: Yelin
authors.forename: Israel
authors.initials: I
authors.lastname: Alfonso
mesh_terms: D002531:Cerebellum / Q000473:pathology* / Q000821:virology*; D020803:Encephalitis, Herpes Simplex / Q000150:complications* / Q000175:diagnosis; D005260:Female; D018258:Herpesvirus 2, Human / Q000472:pathogenicity*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008279:Magnetic Resonance Imaging; D015835:Ocular Motility Disorders / Q000209:etiology*; D014057:Tomography, X-Ray Computed