[Clinical therapy of severe acute respiratory syndrome: 38 cases retrospective analysis].
OBJECTIVE
To analyze the clinical features and therapy experience of severe acute respiratory syndrome (SARS).


METHODS
From December 2002 to April 2003 in Guangzhou Institute of Respiratory Disease, 38 patients with severe SARS were retrospectively studied to evaluate the relationship between treatment strategy and prognosis.


RESULTS
Thirty-eight cases of severe SARS were diagnosed. Comprehensive measures most commonly included corticosteroids, antibiotics, antivirotics, nutritional support and mechanical ventilation. Thirty cases were cured (78.9%), of them 11 cases had pulmonary fibrosis (36.7%), 8 patients died (21.1%) in all cases.


CONCLUSIONS
Severe SARS might develop rapidly. In addition to early diagnosis, prompt isolation, and emergency therapy, appropriate use of corticosteroid and noninvasive ventilation should be recommended.
Xu
Yuan-da
YD
Guangzhou Institute of Respiratory Disease, Yingdong Critical Care Medical Center, Guangzhou 510120, Guandong, China.
Li
Yi-min
YM
Liu
Xiao-qing
XQ
Chen
Si-bei
SB
He
Wei-qun
WQ
Xiao
Zheng-lun
ZL
Zhong
Nan-shan
NS
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018529:Nutritional Support; D011658:Pulmonary Fibrosis / Q000150:complications; D012121:Respiration, Artificial; D012189:Retrospective Studies; D045169:Severe Acute Respiratory Syndrome / Q000150:complications / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D000998:Antiviral Agents