title: Closing another gap in the plant SAR puzzle.
abstract: NPR1 is a key regulator of the salicylic acid (SA) dependent pathogen resistance pathway in plants. In this issue of Cell, Mou and Dong demonstrate that Arabidopsis NPR1 undergoes activation from an inactive oligomer to the active monomer as a result of cellular redox changes induced by SA during systemic acquired resistance.
authors.affiliation: Max-Planck-Institut für Zuechtungsforschung, Abteilung Molekulare Phytopathologie, Carl-von-Linné Weg 10, D-50829, Koeln, Germany.
authors.forename: Imre E
authors.initials: IE
authors.lastname: Somssich
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D007113:Immunity, Innate / Q000235:genetics*; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species / Q000378:metabolism; D020156:Salicylic Acid / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; C105496:NPR1 protein, Arabidopsis; D017382:Reactive Oxygen Species; D020156:Salicylic Acid