title: Plasma lipid modifications in elderly people after administration of two virgin olive oils of the same variety (Olea europaea var. hojiblanca) with different triacylglycerol composition.
abstract: In the present study we examined whether two virgin olive oils (VOO1 and VOO2), of the same variety (Olea europaea var. hojiblanca with a similar composition of minor components but differing in the content of triacylglycerol molecular species, had different effects on blood pressure and plasma lipid levels in a healthy elderly population. Thirty-one participants, aged 84-9 (SD 6.4) years, were asked to participate in the study. No differences were found with regard to blood pressure after both experimental periods (VOO1 and VOO2). However, plasma total cholesterol and LDL-cholesterol were reduced only after VOO1 (P<0.01). The reduction of plasma cholesterol concentrations was related to the incorporation of oleic acid into plasma cholesteryl esters and phospholipids strongly correlated with plasma total cholesterol and LDL-cholesterol levels in all experimental periods studied (r2>0.418, P<0.07), except for phospholipids in VOO1 (P=0.130 for total cholesterol and p=0.360 for LDL-cholesterol). These results have demonstrated that blood pressure and plasma lipids can be modified by the consumption of VOO in elderly people, but that the extent of such modification depends on the composition and amount of active minor components and triacylglycerol molecular species.
authors.affiliation: Instituto de la Grasa, Consejo Superior de Investigaciones Científicas, 41012 Sevilla, Spain.
authors.forename: Javier S
authors.initials: JS
authors.lastname: Perona
authors.forename: Julio
authors.initials: J
authors.lastname: Cañizares
authors.forename: Emilio
authors.initials: E
authors.lastname: Montero
authors.forename: José M
authors.initials: JM
authors.lastname: Sánchez-Domínguez
authors.forename: Valentina
authors.initials: V
authors.lastname: Ruiz-Gutierrez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001794:Blood Pressure; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D002788:Cholesterol Esters / Q000737:chemistry; D008078:Cholesterol, LDL / Q000032:analysis / Q000097:blood; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D031658:Olea; D000069463:Olive Oil; D010743:Phospholipids / Q000737:chemistry; D010938:Plant Oils / Q000008:administration & dosage* / Q000737:chemistry; D014280:Triglycerides / Q000008:administration & dosage* / Q000032:analysis
chemical_list: D002788:Cholesterol Esters; D008078:Cholesterol, LDL; D004042:Dietary Fats, Unsaturated; D008055:Lipids; D000069463:Olive Oil; D010743:Phospholipids; D010938:Plant Oils; D014280:Triglycerides; D002784:Cholesterol