title: Instrumental dead space in neonatology, and its elimination by continuous tracheal gas insufflation during conventional ventilation.
abstract: Instrumental dead space (iDS) is a major part of total dead space in newborns, and thus significantly determines effective alveolar ventilation. Continuous tracheal gas insufflation (CTGI) is a method for reducing the role of iDS, allowing a reduction in respiratory support and secondary lung injury. The literature and authors' experience with the method are reviewed. Major attention is paid to the risks in providing CTGI, optimal equipment and optimal management of CTGI.
authors.affiliation: Pediatric Department, University Hospital, Hradec Kralove, Czech Republic. kalous@fnhk.cz
authors.forename: P
authors.initials: P
authors.lastname: Kalous
authors.forename: Z
authors.initials: Z
authors.lastname: Kokstein
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007327:Insufflation; D007442:Intubation, Intratracheal; D009359:Neonatology; D012121:Respiration, Artificial; D012126:Respiratory Dead Space / Q000502:physiology*; D012127:Respiratory Distress Syndrome, Newborn / Q000503:physiopathology* / Q000628:therapy*; D012720:Severity of Illness Index