Wegener's granulomatosis presenting with otologic and neurologic symptoms: clinical and pathological correlations.
A case of Wegener's granulomatosis in a 59-year-old woman is reported. The disease first involved the parotid gland, the brain stem and the spinal cord, then running a rapidly progressive course as systemic pathology. Anti-neutrophil cytoplasmic antibody (cANCA) levels raised as renal failure set in. Renal biopsy confirmed the diagnosis of Wegener's granulomatosis and an appropriate therapy was adopted.
Bucolo
Sebastiano
S
Departement of Otorhinolaryngology, Torino Nord Emergenza, Ospedale San Giovanni Bosco, Piazza Donatori del Sangue, Torino, Italy. sicseba@yahoo.it
Torre
Valerio
V
Montemagno
Alberto
A
Beatrice
Fabio
F
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D001927:Brain Diseases / Q000175:diagnosis / Q000473:pathology; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000473:pathology; D018450:Disease Progression; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000473:pathology; D006311:Hearing Disorders / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D010033:Otitis Media / Q000175:diagnosis / Q000473:pathology; D010305:Parotid Diseases / Q000175:diagnosis* / Q000473:pathology; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000473:pathology
D019268:Antibodies, Antineutrophil Cytoplasmic