Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action.
Razavi
Hossein
H
Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Palaninathan
Satheesh K
SK
Powers
Evan T
ET
Wiseman
R Luke
RL
Purkey
Hans E
HE
Mohamedmohaideen
Nilofar N
NN
Deechongkit
Songpon
S
Chiang
Kyle P
KP
Dendle
Maria T A
MT
Sacchettini
James C
JC
Kelly
Jeffery W
JW
D000682:Amyloid / Q000037:antagonists & inhibitors*; D001583:Benzoxazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D011228:Prealbumin / Q000037:antagonists & inhibitors*
D000682:Amyloid; D001583:Benzoxazoles; D011228:Prealbumin