title: Paeonianins A-E, new dimeric and monomeric ellagitannins from the fruits of Paeonia lactiflora.
abstract: Four new dimeric ellagitannins, paeonianins A-D (2-5), were isolated from the fruits of Paeonia lactiflora, together with a new ellagitannin monomer, paeonianin E (1). Their structures were determined by spectroscopic methods. Paeonianins A-D (2-5) are positional isomers formed by condensation of pentagalloyl-beta-D-glucose (8) with 5-desgalloylstachyurin (6) or casuariin (7). Paeonianin E is a C-glycosidic ellagitannin having a gallic acid methyl ester moiety at the glucose C-1 position. This is the first report of the isolation of dimeric ellagitannins from a plant in the family Paeoniaceae.
authors.affiliation: Department of Molecular Medicinal Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tanaka
authors.forename: Masatake
authors.initials: M
authors.lastname: Fukumori
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ochi
authors.forename: Isao
authors.initials: I
authors.lastname: Kouno
mesh_terms: D005638:Fruit / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D047348:Hydrolyzable Tannins; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D029596:Paeonia / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D013634:Tannins / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D005960:Glucosides; D047348:Hydrolyzable Tannins; D013634:Tannins; C013515:ellagitannin