title: Linker chain effect of ferrocenyl naphthalene diimide on a double stranded DNA preference.
abstract: Naphthalene diimide derivative 1 carrying two 3-(ferrocenyl-methylamino)-propyl substituents was synthesized as a new hybrid indicator for electrochemical gene sensing. Ligand 1 showed a preference for double stranded DNA four-times larger than 2 previously described. The peak potential of 1 shifted 30 mV toward the negative side from that of 2, thereby shortening the time required for gene detection.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka 812-8581, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Takamiya
authors.forename: K
authors.initials: K
authors.lastname: Yamashita
authors.forename: M
authors.initials: M
authors.lastname: Takagi
authors.forename: H
authors.initials: H
authors.lastname: Kondo
authors.forename: S
authors.initials: S
authors.lastname: Takenaka
mesh_terms: D015374:Biosensing Techniques; D004247:DNA / Q000032:analysis* / Q000378:metabolism; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry* / Q000378:metabolism; D007094:Imides / Q000737:chemistry* / Q000378:metabolism; D007700:Kinetics; D008024:Ligands
chemical_list: D005296:Ferrous Compounds; D007094:Imides; D008024:Ligands; C406363:ferrocenylnaphthalene diimide; D004247:DNA