title: [Effects of 21 d -6 degrees head down bed-rest on pulmonary gas distribution and little airway function].
abstract: OBJECTIVE
  To probe the effect of 21 d -6 degrees head down bed-rest (HDBR) on pulmonary gas distribution and little airway function.
  
  
  METHODS
  The indices of the pulmonary gas distribution and little airway function (delta N2, CV, CV/VC%, LCI) were measured in 16 healthy male subjects before, during and after 21 d -6 degrees HD-BR.
  
  
  RESULTS
  Comparing with before and early days of HDBR, recovery supine delta N2 increased significantly. CV increased significantly only on the first day of HDBR, and changes of CV/VC% were same as CV. The changes of LCI were not significant.
  
  
  CONCLUSIONS
  The indices of pulmonary gas distribution were affected by 21 d -6 degrees HDBR. Pulmonary gas distribution was more uneven during and after 21 d -6 degrees HDBR.
authors.affiliation: The 371 of PLA Hospital, Xinxiang, China.
authors.forename: Shi-qiang
authors.initials: SQ
authors.lastname: Wei
authors.forename: Shuang-ning
authors.initials: SN
authors.lastname: Su
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Lu
authors.forename: Yong-zhi
authors.initials: YZ
authors.lastname: Li
authors.forename: Chong-fa
authors.initials: CF
authors.lastname: Zhong
authors.forename: Hong-ru
authors.initials: HR
authors.lastname: Ren
mesh_terms: D000293:Adolescent; D000328:Adult; D001510:Bed Rest; D018475:Head-Down Tilt; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000502:physiology*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012123:Pulmonary Ventilation / Q000502:physiology*; D012129:Respiratory Function Tests; D012143:Respiratory Physiological Phenomena; D016683:Supine Position; D018474:Weightlessness Simulation
chemical_list: D009584:Nitrogen