Striatal infarcts mimicking frontotemporal dementia: a case report.
We described a patient with bilateral striatal infarcts, in whom stereotyped and disinhibited behaviors were insidiously emerged over 2 years mimicking frontotemporal dementia (FTD). A positron emission tomography with 18-fluorodeoxy glucose showed a hypometabolism in the frontal lobes, basal ganglia, and thalami. The peculiar behavioral alterations remained unchanged for the following 7 years, suggesting that the disease is not degenerative but of vascular origin. A disruption of the fronto-subcortical circuits at the level of the striatum or the anterior thalamic peduncle is attributable to the FTD-like behavioral and cognitive syndrome.
Nishio
Y
Y
Division of Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan.
Nakano
Y
Y
Matsumoto
K
K
Hashimoto
M
M
Kazui
H
H
Hirono
N
N
Ishii
K
K
Mori
E
E
D000368:Aged; D020520:Brain Infarction / Q000473:pathology*; D003342:Corpus Striatum / Q000473:pathology*; D003704:Dementia / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D011859:Radiography; D014055:Tomography, Emission-Computed / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon
D019788:Fluorodeoxyglucose F18