title: Bordetella bronchiseptica persists in the nasal cavities of mice and triggers early delivery of dendritic cells in the lymph nodes draining the lower and upper respiratory tract.
abstract: Early after the intranasal instillation of Bordetella bronchiseptica into mice, not only are mature dendritic leukocytes recovered from lung parenchyma and bronchoalveolar lavage fluid but their numbers are also increased in the mediastinal lymph nodes and the nasal mucosa-associated lymphoid tissue. Later during the infectious process, the bacteria persist mainly in the nasal cavity.
authors.affiliation: Unité des Bordetella, Institut Pasteur, Paris, France. pgueirar@pasteur.fr
authors.forename: Pascale
authors.initials: P
authors.lastname: Gueirard
authors.forename: Patrick
authors.initials: P
authors.lastname: Ave
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Balazuc
authors.forename: Sabine
authors.initials: S
authors.lastname: Thiberge
authors.forename: Michel
authors.initials: M
authors.lastname: Huerre
authors.forename: Genevieve
authors.initials: G
authors.lastname: Milon
authors.forename: Nicole
authors.initials: N
authors.lastname: Guiso
mesh_terms: D000818:Animals; D016950:Bordetella bronchiseptica / Q000502:physiology*; D039521:CD11c Antigen / Q000032:analysis; D002465:Cell Movement; D003713:Dendritic Cells / Q000502:physiology*; D005260:Female; D007962:Leukocytes / Q000276:immunology; D008168:Lung / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology*; D008221:Lymphoid Tissue / Q000276:immunology / Q000382:microbiology; D051379:Mice; D008807:Mice, Inbred BALB C; D009296:Nasal Cavity / Q000382:microbiology*
chemical_list: D039521:CD11c Antigen