title: Stereoselective trimerization of [(S)R]-[(p-tolylsulfinyl)methyl]-p-quinols and p-quinamines.
abstract: [reaction: see text] The asymmetric synthesis of pentacyclic derivatives was achieved in a single step starting from enantiopure [(S)R]-[(p-tolylsulfinyl)methyl]-p-quinols or the nitrogen analogue, through a domino sequence involving four conjugate additions in excellent yields. Eight new stereogenic centers were created in one step and in a highly diastereoselective manner.
authors.affiliation: Departamento de Química Orgánica (C-I), Universidad Autónoma, Cantoblanco, 28049-Madrid, Spain. carmen.carrenno@uam.es
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Carreño
authors.forename: María
authors.initials: M
authors.lastname: Ribagorda