Transmission, acute HIV-1 infection and the quest for strategies to prevent infection.
By the acute stage of HIV-1 infection, the immune system already faces daunting challenges. Research on mucosal barriers and the events immediately after heterosexual transmission that precede this acute stage could facilitate the development of effective microbicides and vaccines.
Pope
Melissa
M
Center for Biomedical Research, Population Council, 1230 York Avenue, New York 10021, USA.
Haase
Ashley T
AT
D016915:AIDS Vaccines / Q000494:pharmacology; D000208:Acute Disease; D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission*; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D008597:Menstrual Cycle; D009092:Mucous Membrane / Q000502:physiology / Q000821:virology*; D012661:Semen / Q000821:virology; D016097:Simian Acquired Immunodeficiency Syndrome / Q000635:transmission; D015302:Simian Immunodeficiency Virus / Q000472:pathogenicity; D014621:Vagina / Q000502:physiology / Q000821:virology
D016915:AIDS Vaccines