Malignant otitis externa due to Aspergillus niger.
The case is reported of a 73-y-old diabetic man with malignant otitis externa due to Aspergillus niger. Cure was achieved with a 3 week course of intravenous amphotericin B, followed by oral itraconazole for 3 months. The characteristics and the outcome of 13 reported cases of malignant otitis externa caused by Aspergillus sp. are presented.
Bellini
Cristina
C
Division of Infectious Diseases, Hospital of Lugano, Switzerland.
Antonini
Pietro
P
Ermanni
Stefano
S
Dolina
Marisa
M
Passega
Eliana
E
Bernasconi
Enos
E
D000284:Administration, Oral; D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage*; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy; D001234:Aspergillus niger / Q000302:isolation & purification*; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D010032:Otitis Externa / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B