Eyelid phakomatous choristoma.
OBJECTIVE
To report a case of congenital phakomatous choristoma (PC) of the eyelid, a rare tumor of lenticular anlage in the subcutaneous tissue and dermis.


METHODS
A boy had a mass in the right lower eyelid near the inner canthus at birth. At age 10 months, the tumor was excised.


RESULTS
The tumor cells showed intense immunoreactivity positive for S-100 protein, vimentin, and periodic acid-Schiff. Keratin markers, epithelial membrane antigen, glial fibrillary acidic protein, muscle specific actin, and epithelial membrane antigen were negative. The histopathologic features were consistent with those of a PC.


CONCLUSIONS
This histopathologic and immunoreactivity study supports the proposal that PC is a rare entity of lenticular anlage origin. Only 18 such cases have been described previously.
Mencía-Gutiérrez
E
E
Department of Ophthalmology, Octubre Hospital, Complutense University, Madrid, Spain. emencia.hdoc@salud.madrid.org
Gutiérrez-Díaz
E
E
Ricoy
J R
JR
Sarmiento-Torres
B
B
D015415:Biomarkers / Q000032:analysis; D002828:Choristoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005136:Eye Proteins / Q000378:metabolism; D005141:Eyelid Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007908:Lens, Crystalline; D008297:Male
D015415:Biomarkers; D005136:Eye Proteins