title: Reactivity of 2-acylaminoacrylates with ketene diethyl acetal; [2 + 2] cycloadditions vs. tandem condensations.
abstract: The reactivity of 2-acylaminoacrylates with ketene diethyl acetal can be modulated by means of thermal conditions to yield cyclobutanes for the preparation of protected beta-hydroxycyclobutane-alpha-amino acids, or catalytic conditions that yield cyclohexanes by tandem condensations to obtain interesting building blocks that are alternatives to Danishefsky's diene.
authors.affiliation: Departamento de Química, Universidad de La Rioja, UA-CSIC, 26006 Logroño, Spain. alberto.avenoza@dq.unirioja.es
authors.forename: Alberto
authors.initials: A
authors.lastname: Avenoza
authors.forename: Jesús H
authors.initials: JH
authors.lastname: Busto
authors.forename: Noelia
authors.initials: N
authors.lastname: Canal
authors.forename: Jesús M
authors.initials: JM
authors.lastname: Peregrina