Membrane activity of biotechnological peptide drugs.
Charged Langmuir-Blodgett monolayers deposited at an immobilised liquid-liquid interface have been used as a simple model for a biological membrane to investigate the membrane activity of biotechnological oligopeptide drugs.
Malkia
Annika
A
Laboratory of Physical Chemistry and Electrochemistry, Helsinki University of Technology, PO Box 6100, FIN-02015 HUT, Finland.
Liljeroth
Peter
P
Kontturi
Kyösti
K
D001709:Biotechnology; D025802:Electric Capacitance; D004563:Electrochemistry / Q000379:methods; D007987:Gonadotropin-Releasing Hormone / Q000737:chemistry / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D057927:Hydrophobic and Hydrophilic Interactions; D008566:Membranes / Q000737:chemistry / Q000187:drug effects*; D017274:Nafarelin / Q000737:chemistry / Q000494:pharmacology; D036361:Peptide Hormones / Q000494:pharmacology*; D055672:Static Electricity; D013499:Surface Properties / Q000187:drug effects
D036361:Peptide Hormones; D017274:Nafarelin; D007987:Gonadotropin-Releasing Hormone