title: [Heterotopic gray matter. Report of four pediatric cases].
abstract: Severe infant epilepsy is included within difficult etiologic diagnosis. Gray matter heterotopias are an uncommon cause. The authors report four observations of gray matter heteropias concerning three-, six-, seven- and nine-year-old girls, presenting no particular antecedents. No consanguinity was noted. The first occurrence of epilepsy ranged from the age of nine months to the age of four years. A mild mental retardation was found in three cases, and mental regression in one case. A status epilepticus was noted in three children. Magnetic resonance imaging scans showed subependymal heterotopias in one case and diffuse cortical heterotopias in three cases associated to a partial agenesis of corpus calloseum in one case and pachygyria in two cases.
authors.affiliation: Service de pédiatrie générale, hôpital d'enfants de Tunis, 1007 Jebbari, bab Saadoun, Tunis, Tunisie. sonia.mrad@rns.tn
authors.forename: S Mazigh
authors.initials: SM
authors.lastname: Mrad
authors.forename: N
authors.initials: N
authors.lastname: Aloui
authors.forename: A
authors.initials: A
authors.lastname: Ben Jeddou
authors.forename: I
authors.initials: I
authors.lastname: Fetni
authors.forename: F
authors.initials: F
authors.lastname: Oubich
authors.forename: S
authors.initials: S
authors.lastname: Boukthir
authors.forename: A
authors.initials: A
authors.lastname: Hammou
authors.forename: S
authors.initials: S
authors.lastname: Barsaoui
mesh_terms: D001927:Brain Diseases / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000150:complications*; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging