Malignant struma ovarii: a case report of laparoscopic management.
BACKGROUND
Struma ovarii is a rare disease. Malignant transformation is even rarer. Data about its management are lacking. We describe the first reported case of a malignant struma ovarii treated and staged by laparoscopy.


METHODS
A 49-year-old patient was operated by laparoscopy for a right ovarian teratoma. The patient did not show symptoms of hyperthyroidism. The ovarian teratoma was removed in a plastic bag and definitive histology showed foci of papillary adenocarcinoma in a struma ovarii. The patient was then staged by laparoscopic surgery undergoing left adnexectomy, multiple peritoneal and omental biopsies, and common iliac and paracaval lymph node sampling. Hysterectomy was not performed. The postoperative course was uneventful and the patient was released on the second day. Thyroglobulin level was monitored and the patient is free of disease after more than 1 year.


CONCLUSIONS
The preoperative diagnosis of malignant struma ovarii is difficult. Even with cautious evaluation of the patient, some risk of wrong diagnosis is possible. This is why a meticulous technique of laparoscopic surgery in removing the ovary is important. Laparoscopic staging may also intervene in very limited cases; the expertise to perform open staging of the patient is necessary but the postoperative course is fast.
Volpi
E
E
Department of Gynecologic Oncology, University of Turin, Turin, Italy. ginecologia@mauriziano.it
Ferrero
A
A
Nasi
P G
PG
Sismondi
P
P
D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D013330:Struma Ovarii / Q000473:pathology / Q000601:surgery*; D013964:Thyroid Neoplasms / Q000473:pathology*