Normal brain aging: a commentary.
Brain gerontology encounters problems that, analogically, are similar with those encountered in biogerontology in general. These problems are namely interactions between aging per se, stress response and bioenergetics. These interaction exist for instance as concerns cross-talks between stress response- and senescence-specific signaling pathways. Analogies with replicative senescence and stress-induced premature senescence are drawn.
Toussaint
Olivier
O
University of Namur (FUNDP), Unit of Cellular Biochemistry & Biology, Rue de Bruxelles 61, 5000 Namur, Belgium. olivier.toussaint@fundp.ac.be
D000375:Aging / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000502:physiology*; D006801:Humans