title: Photoelectron spectra of important drug molecules: zidovudine and artemisinine.
abstract: The electronic structures of the anti-HIV drug zidovudine (AZT) and antimalarial drug artemisinine have been investigated by UV photoelectron spectroscopy (UPS), MO calculations, and comparison with the spectra of related molecules. The analysis of their electronic structure is correlated with known biological activities.
authors.affiliation: Department of Chemistry, National University of Singapore, Singapore 117543, Singapore. chmigorn@nus.edu.sg
authors.forename: Igor
authors.initials: I
authors.lastname: Novak
authors.forename: Branka
authors.initials: B
authors.lastname: Kovac
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry; D037621:Artemisinins / Q000737:chemistry*; D004583:Electrons; D008958:Models, Molecular; D012717:Sesquiterpenes / Q000737:chemistry*; D013057:Spectrum Analysis; D013329:Structure-Activity Relationship; D015215:Zidovudine / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D037621:Artemisinins; D012717:Sesquiterpenes; D015215:Zidovudine; C031327:artemisinin