title: Mapping of 19032 mouse cDNAs on mouse chromosomes.
abstract: Finding genes by the positional candidate approach requires abundant cDNAs mapped to chromosomes. To provide such important information, we computationally mapped 19032 of our mouse cDNAs to mouse chromosomes by using data from public databases. We used 2 approaches. In the first, we integrated the mapping data of cDNAs on the human genome, known gene-related data, and comparative mapping data. From this, we calculated map positions on the mouse chromosomes. For this first approach, we developed a simple and powerful criterion to choose the correct map position from candidate positions in sequence homology searches. In the second approach, we related cDNAs to expressed sequence tags (EST) previously mapped in radiation hybrid experiments. We discuss improving the mapping by combining the 2 methods.
authors.affiliation: Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences Center (GSC), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa 230-0045, Japan.
authors.forename: Itaru
authors.initials: I
authors.lastname: Yamanaka
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kiyosawa
authors.forename: Shinji
authors.initials: S
authors.lastname: Kondo
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Saito
authors.forename: Piero
authors.initials: P
authors.lastname: Carninci
authors.forename: Akira
authors.initials: A
authors.lastname: Shinagawa
authors.forename: Katsunori
authors.initials: K
authors.lastname: Aizawa
authors.forename: Shiro
authors.initials: S
authors.lastname: Fukuda
authors.forename: Ayako
authors.initials: A
authors.lastname: Hara
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Itoh
authors.forename: Jun
authors.initials: J
authors.lastname: Kawai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Shibata
authors.forename: Takahiro
authors.initials: T
authors.lastname: Arakawa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ishii
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Hayashizaki
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D018076:DNA, Complementary / Q000235:genetics*; D030561:Databases, Nucleic Acid; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D051379:Mice
chemical_list: D018076:DNA, Complementary; D005819:Genetic Markers