Antifungal activity of Piper guineense of Cameroon.
The antifungal activity of the ethanol extract of the seeds of Piper guineense and some of its fractions obtained by column chromatography was investigated using filamentous fungi and yeasts. The results indicated a significant antifungal effect. No toxic effect was observed in mice treated per os with the extract.
Ngono Ngane
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Laboratoire de Biochimie, Faculté des Sciences BP 24157, Douala, Cameroon. angono@yahoo.com
Biyiti
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Bouchet
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Nkengfack
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Amvam Zollo
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PH
D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002163:Cameroon; D004305:Dose-Response Relationship, Drug; D005260:Female; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D007928:Lethal Dose 50; D008297:Male; D016488:Medicine, African Traditional; D051379:Mice; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D031701:Piper; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012639:Seeds; D015003:Yeasts / Q000187:drug effects
D000935:Antifungal Agents; D010936:Plant Extracts