Biotransformation of a dibenzylbutanolide to podophyllotoxin analogues by shoot cultures of Haplophyllum patavinum.
A peroxidase from spent medium of shoot cultures from Haplophyllum patavinum (L.) G. Don catalyzes the biotransformation of a synthetic dibenzybutanolide into a podophyllotoxin analogue and a novel compound, derived by the opening of the lactone ring.
Puricelli
Lucia
L
Dipartimento di Biologia, Università di Padova, Italy.
Caniato
Rosy
R
Delle Monache
Giuliano
G
D001711:Biotransformation; D000440:Butanols / Q000737:chemistry* / Q000378:metabolism*; D010936:Plant Extracts / Q000737:chemistry / Q000378:metabolism; D018520:Plant Shoots; D011034:Podophyllotoxin / Q000031:analogs & derivatives* / Q000378:metabolism*; D027821:Rutaceae
D000440:Butanols; D010936:Plant Extracts; D011034:Podophyllotoxin