title: Ventricular reconstruction for ischemic cardiomyopathy.
abstract: Left ventricular surgical reconstruction has been advocated for patients with coronary artery disease, prior myocardial infarction, and poor left ventricular function. The objective of the approach is to resect or exclude all akinetic or dyskinetic nonfunctioning portions of the ventricular cavity and to restore the left ventricle size and shape toward normal as much as possible. We review the pathophysiology of ischemic cardiomyopathy and suggest guidelines for preoperative assessment and patient selection for ventricular reconstruction. Because of the prevalence and prognostic significance of ventricular arrhythmias in this patient population we include in our operative approach a visually directed ablation procedure in those with significant septal scarring. We describe our operative technique and review results achieved with this approach. The procedure results in a significant decrease in ventricular volume, increase in ejection fraction and improvement in apical geometry. We conclude that in selected patients with ischemic cardiomyopathy, left ventricular reconstruction can be accomplished with low operative mortality and results in significant improvement in left ventricular function. During follow up symptom class is decreased in most patients and overall survival at 5 years is 84% and freedom from sudden death is 96%. Ventricular reconstruction should be considered in all patients with coronary artery disease and akinetic or dyskinetic scar.
authors.affiliation: Division of Cardiovascular Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. lynda.mickleborough@uhn.on.ca
authors.forename: Lynda L
authors.initials: LL
authors.lastname: Mickleborough
authors.forename: Naeem
authors.initials: N
authors.lastname: Merchant
authors.forename: Yves
authors.initials: Y
authors.lastname: Provost
authors.forename: Susan
authors.initials: S
authors.lastname: Carson
authors.forename: Joan
authors.initials: J
authors.lastname: Ivanov
mesh_terms: D006352:Heart Ventricles / Q000601:surgery*; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000601:surgery*; D016277:Ventricular Function, Left