title: Amoxicillin-induced nephritis and tubulitis in a child.
abstract: The occurrence of interstitial nephritis in patients receiving antimicrobial therapy has frequently been reported in adults while it has rarely been described in children. We report the case of a patient treated with amoxicillin who presented hallucinations and serosanguineous blisters during treatment and developed renal failure a few days after discontinuation of the drug. On renal biopsy an interstitial nephritis with tubulitis was identified.
authors.affiliation: Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, Italy. pietro.ferrara@mailcity.com
authors.forename: Pietro
authors.initials: P
authors.lastname: Ferrara
authors.forename: Carmen M
authors.initials: CM
authors.lastname: D'Aleo
authors.forename: Donato
authors.initials: D
authors.lastname: Rigante
authors.forename: Fabrizia
authors.initials: F
authors.lastname: Paolini Paoletti
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Zannoni
authors.forename: Laura
authors.initials: L
authors.lastname: Venuti
authors.forename: Carlo
authors.initials: C
authors.lastname: Fundarò
authors.forename: Claudia
authors.initials: C
authors.lastname: Rendeli
authors.forename: Elio
authors.initials: E
authors.lastname: Salvaggio
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology; D000658:Amoxicillin / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy; D010406:Penicillins / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D010406:Penicillins; D000658:Amoxicillin; D011241:Prednisone