A novel redox reaction between 8-aza-5,7-dimethyl-2-trifluoromethylchromone and alkyl mercaptoacetates.
[reaction: see text] 8-Aza-5,7-dimethyl-2-trifluoromethylchromone reacts with alkyl mercaptoacetates to give pyrido derivatives of 2-oxa-7-thiabicyclo[3.2.1]octane, which undergo the reductive ring-opening to sulfanyl acetates. The latter compounds are useful CF(3)-containing building blocks for the preparation of a variety of 2-pyridone derivatives.
Sosnovskikh
Vyacheslav Ya
VY
Department of Chemistry, Ural State University, Lenina 51, 620083 Ekaterinburg, Russia. vyacheslav.sosnovskikh@usu.ru
Barabanov
Mikhail A
MA
Usachev
Boris I
BI