Maternal respiratory syncytial virus antibody titers: season and children matter.
The seasonal variation in concentrations of maternal serum antibodies to respiratory syncytial virus fusion protein was investigated with the use of 761 maternal sera at delivery of term infants during a 12-month period. Mean antibody titers were significantly higher between April and September and significantly higher in women who already had children at home.
Le Saux
Nicole
N
Division of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Gaboury
Isabelle
I
MacDonald
Noni
N
D000914:Antibodies, Viral / Q000032:analysis*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D008431:Maternal-Fetal Exchange / Q000502:physiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011256:Pregnancy Outcome; D011336:Probability; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000635:transmission*; D012136:Respiratory Syncytial Viruses / Q000276:immunology*; D012307:Risk Factors; D012621:Seasons
D000914:Antibodies, Viral