Evaluation of abnormal liver function tests.
Interpretation of abnormalities in liver function tests is a common problem faced by clinicians. This has become more common with the introduction of automated routine laboratory testing. Not all persons with one or more abnormalities in these tests actually have liver disease. The various biochemical tests, their pathophysiology, and an approach to the interpretation of abnormal liver function tests are discussed in this review.
Limdi
J K
JK
Tameside General Hospital, Ashton-under-Lyne, Manchester, UK. limdi@aol.com
Hyde
G M
GM
D000469:Alkaline Phosphatase / Q000378:metabolism; D001663:Bilirubin / Q000097:blood; D001780:Blood Coagulation Tests; D006432:Hemochromatosis / Q000175:diagnosis; D019693:Hepatitis, Autoimmune / Q000175:diagnosis; D006527:Hepatolenticular Degeneration / Q000175:diagnosis; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D008111:Liver Function Tests; D008487:Medical History Taking; D010808:Physical Examination; D013231:Steatitis / Q000175:diagnosis; D000637:Transaminases / Q000378:metabolism; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D005723:gamma-Glutamyltransferase; D000637:Transaminases; D000469:Alkaline Phosphatase; D001663:Bilirubin