title: [Paraquat intoxication].
abstract: Paraquat, widely used as a contact herbicide is, in some environments (meanly rural), the principal mean of suicide. Commercially known as Gramoxone, it was sintetyzed for the first time in 1882 and its herbicide properties were not discovered until 1955. The authors made a literature review and describe the historic perspective, physicochemical properties, clinic aspects, prognosis factors and treatment and, finally, propose a therapeutic approach having always in mind the capital importance of the early beginning of general treatment of intoxication cases.
authors.affiliation: Serviço de Nefrologia, Hospital de Santa Maria, Lisboa.
authors.forename: Adelaide
authors.initials: A
authors.lastname: Serra
authors.forename: Fernando
authors.initials: F
authors.lastname: Domingos
authors.forename: M Martins
authors.initials: MM
authors.lastname: Prata
mesh_terms: D002319:Cardiovascular System / Q000187:drug effects; D004064:Digestive System / Q000187:drug effects; D004231:Diuresis; D006464:Hemoperfusion; D006540:Herbicides / Q000009:adverse effects* / Q000378:metabolism / Q000506:poisoning; D006801:Humans; D008099:Liver / Q000187:drug effects; D010179:Pancreas / Q000187:drug effects; D010269:Paraquat / Q000009:adverse effects* / Q000378:metabolism / Q000506:poisoning; D006435:Renal Dialysis; D012137:Respiratory System / Q000187:drug effects
chemical_list: D006540:Herbicides; D010269:Paraquat