Pattern recognition methods in evaluation of the structure of the laboratory data biominerals, antioxidant enzymes, selected biochemical parameters, and pulmonary function of welders.
A wide set of biochemical and spirometrical parameters was applied to a group of 41 welders. The obtained parameters were analyzed by the pattern recognition method: principal-components analysis (PCA) and mutual contribution analysis (MCA). The aim of the investigation was to find out which of 23 parameters had an influence on the pulmonological indices of COPD. It was found that PCA gave a substantial reduction of dimensionality. The most relevant parameters were Fe, Zn, Cu (all elements in blood, not in hair), FEV1, MEF50, bilirubin, TAS, and SOD. Only the relationships of MEF50, Cu, and TAS were statistically valid.
Stepniewski
Marek
M
Radioligand Laboratory of the Pharmacy Faculty, Collegium Medicum Jagiellonian University, 9 Medyczna str, 30-688 Kraków, Poland.
Kolarzyk
Emilia
E
Zagrodzki
Pawel
P
Solarska
Katarzyna
K
Pietrzycka
Agata
A
Kitlinski
Mariusz
M
Schlegel-Zawadzka
Malgorzata
M
Batko
Bogdan
B
D000328:Adult; D000367:Age Factors; D000395:Air Pollutants, Occupational / Q000032:analysis / Q000097:blood; D000975:Antioxidants / Q000032:analysis*; D006197:Hair / Q000737:chemistry; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure; D018384:Oxidative Stress; D010363:Pattern Recognition, Automated; D025341:Principal Component Analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000097:blood* / Q000378:metabolism / Q000503:physiopathology*; D012129:Respiratory Function Tests; D013997:Time Factors; D014131:Trace Elements / Q000032:analysis* / Q000097:blood; D014896:Welding
D000395:Air Pollutants, Occupational; D000975:Antioxidants; D014131:Trace Elements