title: Comparison of classification-based physical therapy with therapy based on clinical practice guidelines for patients with acute low back pain: a randomized clinical trial.
abstract: METHODS
  A randomized clinical trial was conducted.
  
  
  OBJECTIVE
  To compare the effectiveness of classification-based physical therapy with that of therapy based on clinical practice guidelines for patients with acute, work-related low back pain.
  
  
  BACKGROUND
  Clinical practice guidelines recommend minimal intervention during the first few weeks after acute low back injury. However, studies supporting this recommendation have not attempted to identify which patients are likely to respond to particular interventions.
  
  
  METHODS
  For this study, 78 subjects with work-related low back pain of less than 3 weeks duration were randomized to receive therapy based on a classification system that attempts to match patients to specific interventions or therapy based on the Agency for Health Care Policy and Research guidelines. The subjects were followed for 1 year. Outcomes included the impairment index, Oswestry scale, SF-36 component scores, satisfaction, medical costs, and return to work status.
  
  
  RESULTS
  After adjustment for baseline factors, subjects receiving classification-based therapy showed greater change on the Oswestry (P = 0.023) and the SF-36 physical component (P = 0.029) after 4 weeks. Patient satisfaction was greater (P = 0.006) and return to full-duty work status more likely (P = 0.017) after 4 weeks in the classification-based group. After 1 year, there was a trend toward reduced Oswestry scores in the classification-based group (P = 0.063). Median total medical costs for 1 year after injury were 1003.68 dollars for the guideline-based group and 774.00 dollars for the classification-based group (P = 0.13).
  
  
  CONCLUSIONS
  For patients with acute, work-related low back pain, the use of a classification-based approach resulted in improved disability and return to work status after 4 weeks, as compared with therapy based on clinical practice guidelines. Further research is needed on the optimal timing and methods of intervention for patients with acute low back pain.
authors.affiliation: Department of Physical Therapy, University of Pittsburgh, PA 15260, USA. jfritz@pitt.edu
authors.forename: Julie M
authors.initials: JM
authors.lastname: Fritz
authors.forename: Anthony
authors.initials: A
authors.lastname: Delitto
authors.forename: Richard E
authors.initials: RE
authors.lastname: Erhard
mesh_terms: D000208:Acute Disease; D000328:Adult; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D017048:Health Care Costs; D006801:Humans; D017116:Low Back Pain / Q000145:classification* / Q000628:therapy*; D008297:Male; D010043:Outcome and Process Assessment, Health Care / Q000706:statistics & numerical data; D010147:Pain Measurement / Q000706:statistics & numerical data; D010414:Pennsylvania; D026741:Physical Therapy Modalities / Q000191:economics / Q000706:statistics & numerical data*; D017410:Practice Guidelines as Topic; D018582:Sick Leave / Q000706:statistics & numerical data; D014481:United States; D016270:United States Agency for Healthcare Research and Quality / Q000592:standards