Structure and properties of carbocyclic 5'-nor oligodeoxynucleotides.
The hybridization properties of carbocyclic 5'-nor oligodeoxynucleotides 1, 2 (24 mer, B = A) with DNA and RNA were investigated by CD melting curves. These oligomers formed unstable duplexes with DNA, but formed stable duplexes with RNA selectively.
Koga
M
M
Department of Applied Chemistry, Faculty of Engineering, Venture Business Laboratory, Ehime University, Matsuyama 790-8577, Japan.
Tamai
K
K
Ueda
M
M
Uchida
T
T
Yamamuro
T
T
Suzuki
T
T
Saeki
T
T
D002942:Circular Dichroism; D003500:Cyclization; D004247:DNA / Q000737:chemistry; D009691:Nucleic Acid Denaturation; D009693:Nucleic Acid Hybridization; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D012313:RNA / Q000737:chemistry; D013696:Temperature
D009838:Oligodeoxyribonucleotides; D012313:RNA; D004247:DNA