title: Breast conservation therapy with concomitant breast reduction in large-breasted women.
abstract: Cosmetic results from radiation following breast-conserving surgery and radiation therapy are generally poorer in women with large or heavy breasts. Breast reduction carried out at the time of definitive surgery allows this group of women to undergo breast-conserving surgery and radiation with excellent cosmetic results. Four cases are presented in which partial mastectomy was carried out in conjunction with immediate bilateral breast reduction. All patients had clear margins and all had excellent cosmetic results following radiation therapy. Immediate breast reduction should be considered in women with large or heavy breasts who otherwise qualify for breast-conserving surgery.
authors.affiliation: Department of Surgery, Ochsner Clinic, Louisiana State University, Memorial Medical Center, New Orleans, Louisiana 70121, USA. astolier@ochsner.org
authors.forename: Alan
authors.initials: A
authors.lastname: Stolier
authors.forename: Robert
authors.initials: R
authors.lastname: Allen
authors.forename: Luis
authors.initials: L
authors.lastname: Linares
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged