Development of a novel compression tester and rheo-mechanical properties of wet-mass powder. II--Effect of moisture content on the rheo-mechanical properties.
In our previous paper [Watano S., et al., Chem. Pharm. Bull., 51(7), 747-750 (2003)], a novel compression tester, which enables the vertical and radial pressure transmission measurement, has been developed and quantitative analysis of rheo-mechanical properties of wet-mass powder prepared by different kneading times was conducted. In this study, the compression test was conducted by using the kneaded wet-mass powders prepared by different moisture contents. Pressure transmission characteristics and rheo-mechanical properties have been investigated to characterize the wet-mass powders. The relationship between these parameters and granule physical properties was also investigated.
Watano
Satoru
S
Department of Chemical Engineering, Osaka Prefecture University, Sakai, Japan. watano@chemeng.osakafu-u.ac.jp
Yoshikawa
Tomoko
T
Osako
Yoshifumi
Y
Tsuhari
Masamitsu
M
D019245:Compressive Strength; D006813:Humidity; D019563:Mechanics; D011208:Powders / Q000737:chemistry*; D012212:Rheology; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods*
D011208:Powders