Elimination of barium sulphate from acrylic bone cements. Use of two iodine-containing monomers.
The aim of this work is to present a new approach to joint arthroplasty failure related to bone cement mantle. As barium sulphate is considered one of the main causes of mechanical weakness in the cement, we substituted this inorganic radiopacifier of the solid component for radiopaque monomers in the liquid component. We obtained two different cements, one containing 5 vol% 2-[2',3',5'-triiodobenzoyl] ethyl methacrylate (TIBMA) and the other containing 3,5-diiodine salicylic methacrylate (DISMA). In both cases, the mechanical properties of these new cements were better than those of the barium sulphate-containing cement. The radiopacity obtained was comparable to that of the aforementioned cement and all the samples showed good biocompatibility.
Artola
A
A
Dpto. Ciencia y Tecnología de Polímeros, Facultad de Química, POLYMAT (Instituto de materiales poliméricos), Universidad del País Vasco, Apdo 1072, 20080-San Sebastián, Spain.
Gurruchaga
M
M
Vázquez
B
B
San Román
J
J
Goñi
I
I
D001466:Barium Sulfate / Q000302:isolation & purification* / Q000494:pharmacology; D001672:Biocompatible Materials / Q000737:chemistry; D001843:Bone Cements / Q000737:chemistry*; D003287:Contrast Media / Q000494:pharmacology; D007455:Iodine / Q000737:chemistry*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008689:Methacrylates / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D013696:Temperature; D013997:Time Factors; D014283:Triiodobenzoic Acids / Q000737:chemistry
D001672:Biocompatible Materials; D001843:Bone Cements; D003287:Contrast Media; D008689:Methacrylates; D014283:Triiodobenzoic Acids; C104156:2-(2',3',5'-triiodobenzoyl)ethyl methacrylate; D001466:Barium Sulfate; D007455:Iodine