title: Adjuvant therapy of colon cancer in idiopathic leukopenia.
abstract: Colorectal cancer is a common malignancy. Surgical resection is the primary treatment modality and the outcome is closely related to the extent of the disease at presentation. Adjuvant chemotherapy with 5-fluorouracil and leucovorin is the standard therapy for resected node-positive disease. This therapy can cause myelosuppression. We present a case of colon cancer with idiopathic leukopenia who tolerated chemotherapy without worsening of leukopenia.
authors.affiliation: Department of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, MeritCare Hospital [RT 170], 720 N. Fourth Street, Fargo, ND 58122, USA. hassanpervez@meritcare.com
authors.forename: Hassan
authors.initials: H
authors.lastname: Pervez
authors.forename: Anil
authors.initials: A
authors.lastname: Potti
authors.forename: Syed A
authors.initials: SA
authors.lastname: Mehdi
mesh_terms: D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000150:complications / Q000188:drug therapy*; D005472:Fluorouracil / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects / Q000627:therapeutic use*; D007970:Leukopenia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged
chemical_list: D002955:Leucovorin; D005472:Fluorouracil