Fatal nucleoside-associated lactic acidosis in an obese woman with human immunodeficiency virus type 1 infection on a very low-calorie diet.
This study reports the case of an obese woman with human immunodeficiency virus type 1 (HIV-1) infection who developed fatal nucleoside-associated lactic acidosis 10 d after she started a weight-loss dietary regimen containing 600 kcal/d. This case suggests that very low-calorie diets may be life threatening for HIV-infected patients receiving nucleoside analogues.
Sipsas
Nikolaos V
NV
Academic Department of Pathophysiology (AIDS Unit), Laikon General Hospital and Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Kosmas
Nikolaos
N
Kontos
Athanasios
A
Eftychiadis
Christos
C
Agapitos
Emmanuel
E
Kordossis
Theodore
T
D000140:Acidosis, Lactic / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage; D001344:Autopsy; D018752:Diet, Fat-Restricted / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D008099:Liver / Q000473:pathology; D009765:Obesity / Q000150:complications / Q000175:diagnosis / Q000178:diet therapy*; D018570:Risk Assessment; D015431:Weight Loss
D019380:Anti-HIV Agents