title: Atropisomeric amides: Achiral ligands with chiral conformations.
abstract: A new class of achiral ligands with atropisomeric conformations has been coordinated to titanium(IV). The ligands are ortho-hydroxy benzamide derivatives which are deprotonated on reaction with titanium tetraisopropoxide to furnish Ti(L)(2)(O-iPr)(2) complexes (L=ortho-phenoxy benzamide). In these octahedral titanium compounds, the ortho-phenoxy benzamide ligands chelate to titanium, bonding through the phenoxide oxygen and the amide carbonyl oxygen. The benzamide ligands adopt atropisomeric conformations with an angle between the aryl and amide groups of approximately 35 degrees. The ligand precursor, ligand, and titanium complexes have been characterized by X-ray crystallography. Only one diastereomer of each titanium complex was observed in the solid state structures.
authors.affiliation: P. Roy and Diane T. Vagelos Laboratories, University of Pennsylvania, Department of Chemistry, Philadelphia, Pennsylvania, USA.
authors.forename: Ayako
authors.initials: A
authors.lastname: Honda
authors.forename: Karen M
authors.initials: KM
authors.lastname: Waltz
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Carroll
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Walsh