Application of an ephedrine chiral linker in a solid-phase, 'asymmetric catch-release' approach to gamma-butyrolactones.
A Sm(II)-mediated, asymmetric, intermolecular ketyl-olefin addition employing alpha,beta-unsaturated esters linked to resin through an ephedrine 'chiral link' has been applied in a direct 'asymmetric catch-release' approach to gamma-butyrolactones.
Kerrigan
Nessan J
NJ
Department of Chemistry, The Joseph Black Building, University of Glasgow, Glasgow, Scotland, UK G12 8QQ.
Hutchison
Panee C
PC
Heightman
Tom D
TD
Procter
David J
DJ