title: Efficient nickel-mediated intramolecular amination of aryl chlorides.
abstract: The use of an in situ generated Ni(0) catalyst associated with 2,2'-bipyridine or N,N'-bis(2,6-diisopropylphenyl)dihydroimidazol-2-ylidene (SIPr) as a ligand and NaO-t-Bu as the base for the intramolecular coupling of aryl chlorides with amines is described. The procedure has been applied to the formation of five-, six-, and seven-membered rings. [reaction: see text]
authors.affiliation: Synthèse Organométallique et Réactivité, UMR CNRS UHP 7565, Université Henri Poincaré, Nancy I, BP 239, 54506 Vandoeuvre les Nancy Cedex, France.
authors.forename: Rafik
authors.initials: R
authors.lastname: Omar-Amrani
authors.forename: Antoine
authors.initials: A
authors.lastname: Thomas
authors.forename: Eric
authors.initials: E
authors.lastname: Brenner
authors.forename: Raphaël
authors.initials: R
authors.lastname: Schneider
authors.forename: Yves
authors.initials: Y
authors.lastname: Fort