title: Melanocytic colonization of a meningothelial meningioma: histopathological and ultrastructural findings with immunohistochemical and genetic correlation: case report.
abstract: OBJECTIVE
  Melanocytic colonization of nonpigmented extracranial tumors has been reported in adenocarcinomas, squamous cell carcinomas, skin appendage tumors, and dermatofibrosarcoma protuberans. To our knowledge, melanocytic colonization of a meningioma has not previously been described.
  
  
  METHODS
  We report an unusual case of a 70-year-old African-American woman who presented with a large frontoparietal meningioma that extended through the calvarium.
  
  
  METHODS
  Craniotomy with gross total resection of the tumor was performed. Histochemistry, immunocytochemistry, ultrastructural analysis, and molecular genetic study via fluorescence in situ hybridization confirmed melanocytic colonization of a meningothelial meningioma.
  
  
  CONCLUSIONS
  With the inclusion of meningothelial meningioma, the spectrum of tumors affected by melanocytic colonization continues to expand.
authors.affiliation: Department of Pathology, West Virginia University, Morgantown, West Virginia 26506, USA. snestor@hsc.wvu.edu
authors.forename: Scott L
authors.initials: SL
authors.lastname: Nestor
authors.forename: Arie
authors.initials: A
authors.lastname: Perry
authors.forename: Ozlem
authors.initials: O
authors.lastname: Kurtkaya
authors.forename: Patrice
authors.initials: P
authors.lastname: Abell-Aleff
authors.forename: Aldo M
authors.initials: AM
authors.lastname: Rosemblat
authors.forename: Peter C
authors.initials: PC
authors.lastname: Burger
authors.forename: Bernd W
authors.initials: BW
authors.lastname: Scheithauer
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008544:Melanocytes / Q000473:pathology* / Q000648:ultrastructure*; D008577:Meningeal Neoplasms / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure*; D008579:Meningioma / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure*