title: [Percutaneous pulmonary valve replacement: towards a modification of the prosthesis].
abstract: Percutaneous pulmonary valve replacement has recently been introduced as an alternative to surgery, pushing back the frontiers of interventional catheterisation. The authors report their experience in this field and focus on the complications of the method. From September 2000 to November 2002, 14 patients with a failing artificial pulmonary outflow tract were included in this protocol of clinical research. The authors attempted pulmonary implantation of a bovine jugular vein valve fitted in a vascular stent under general anaesthesia. The implantation was possible in all patients. Three had dynamic obstruction due to the implanted valve. This was due to infiltration of blood between the valve and the stent. The problem was resolved by: implanting a second valve in one patient: redialating the valve stent in two other patients. However, the last patient had to be reoperated 7 weeks after the implantation because of recurrence of the obstruction. One valve had to be explanted one year after implantation because of severe infectious endocarditis after unprotected dental treatment. Two patients experienced fracture of the stent but without valve dysfunction. Despite these complications, the clinical state of all patients improved during follow-up. The authors conclude that non-surgical pulmonary valve replacement is feasible, thereby increasing the therapeutic arsenal of interventional catheterisation. Simple modifications should result in fewer problems of dynamic obstruction and stent fracture, and lead to proposing this technique for native pulmonary outflow tracts.
authors.affiliation: Service de cardiologie pédiatrique, hôpital Necker-Enfants malades, 149, rue de Sèvres, 75015 Paris.
authors.forename: Y
authors.initials: Y
authors.lastname: Boudjemline
authors.forename: G
authors.initials: G
authors.lastname: Agnoletti
authors.forename: J F
authors.initials: JF
authors.lastname: Piéchaud
authors.forename: L
authors.initials: L
authors.lastname: Iserin
authors.forename: P
authors.initials: P
authors.lastname: Vouhé
authors.forename: D
authors.initials: D
authors.lastname: Bonnet
authors.forename: D
authors.initials: D
authors.lastname: Sidi
authors.forename: P
authors.initials: P
authors.lastname: Bonhoeffer
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002417:Cattle; D002648:Child; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D007601:Jugular Veins / Q000637:transplantation*; D011474:Prosthesis Design; D011664:Pulmonary Valve / Q000601:surgery*; D011665:Pulmonary Valve Insufficiency / Q000601:surgery*; D011666:Pulmonary Valve Stenosis / Q000601:surgery*; D012086:Reoperation; D015607:Stents; D016896:Treatment Outcome