Key issues for the assessment of the allergenic potential of genetically modified foods: breakout group reports.
On the final afternoon of the workshop "Assessment of the Allergenic Potential of Genetically Modified Foods," held 10-12 December 2001 in Chapel Hill, North Carolina, USA, speakers and participants met in breakout groups to discuss specific questions in the areas of use of human clinical data, animal models to assess food allergy, biomarkers of exposure and effect, sensitive populations, dose-response assessment, and postmarket surveillance. Each group addressed general questions regarding allergenicity of genetically modified foods and specific questions for each subject area. This article is a brief summary of the discussions of each of the six breakout groups regarding our current state of knowledge and what information is needed to advance the field.
Germolec
Dori R
DR
Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA. germolec@niehs.nih.gov
Kimber
Ian
I
Goldman
Lynn
L
Selgrade
MaryJane
M
D015415:Biomarkers / Q000032:analysis; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D005512:Food Hypersensitivity / Q000209:etiology* / Q000276:immunology; D030841:Food, Genetically Modified / Q000009:adverse effects*; D006801:Humans; D011358:Product Surveillance, Postmarketing; D012107:Research Design; D018570:Risk Assessment
D015415:Biomarkers