Diverse motifs of mannoside clustering on a beta-cyclodextrin core.
[reaction: see text] A new method for the synthesis of beta-cyclodextrin-based cluster mannosides by application of the Sonogashira cross-coupling reaction is described. The method allows for the persubstitution of the beta-cyclodextrin at either 2- and 3-positions to give two types of heptavalent clusters, at both 2- and 6-positions to give clusters with 14 mannopyranoside units and at 2-, 3-, and 6-positions to obtain clusters with 21 mannopyranoside ligands.
Ortega-Caballero
Fernando
F
Area de Química Orgánica, Universidad de Almería, E-04120 Almería, Spain.
Giménez-Martínez
Juan J
JJ
Vargas-Berenguel
Antonio
A
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D003505:Cyclodextrins / Q000737:chemistry*; D008362:Mannosides / Q000737:chemistry*; D008969:Molecular Sequence Data; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D008362:Mannosides; D047392:beta-Cyclodextrins; C031215:betadex