Pemphigus vulgaris: the eyes have it.
Pemphigus vulgaris is a potentially fatal autoimmune blistering disease that is rare in childhood. We report 2 recent cases seen contemporaneously in adolescents who presented with chronic oral mucosal lesions and conjunctivitis. The previously unemphasized ocular manifestations are described and the importance of a biopsy in establishing the diagnosis in instances of unexplained chronic mucositis is stressed.
Merchant
Saba
S
Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada M5G 1X8.
Weinstein
Michael
M
D000293:Adolescent; D001327:Autoimmune Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001706:Biopsy; D003231:Conjunctivitis / Q000209:etiology*; D003320:Corneal Ulcer / Q000209:etiology; D003680:Deglutition Disorders / Q000209:etiology / Q000628:therapy; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D019226:Oral Ulcer / Q000209:etiology*; D010289:Parenteral Nutrition, Total; D010392:Pemphigus / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
D007166:Immunosuppressive Agents; D011241:Prednisone; D008775:Methylprednisolone