title: Tibial fixation comparison of semitendinosus-bone composite allografts fixed with bioabsorbable screws and bone-patella tendon-bone grafts fixed with titanium screws.
abstract: Tibial fixation remains the weak link of ACL reconstruction over the first 8-12 weeks postoperatively. This study compared the biomechanical properties of tibial fixation for a bone-patellar tendon-bone (BPTB) graft and a novel semitendinosus-bone composite (SBC) allograft with mixed cortical-cancellous bone dowels at each end. Seven paired, fresh frozen cadaveric knees (20-45 years) were stripped of all soft tissue attachments and randomly assigned to receive either the BPTB graft or SBC allograft. Grafts were placed into tibial tunnels via a standard protocol and secured with either a 10 mmx28 mm bioabsorbable (SBC) or titanium (BPTB) screw. Grafts were cycled ten times in a servo hydraulic device from 10-50 N prior to pull to failure testing at a rate of 20 mm/min with the force vector aligned with the tibial tunnel ("worst case scenario"). Wilcoxon Signed Rank Tests were used to evaluate biomechanical differences between graft types ( p<0.05). Tibial bone mineral density and interference screw insertion torque were statistically equivalent between graft types. The mode of failure for all constructs was direct screw and graft construct pullout from the tibial tunnel. Significant differences were not observed between graft types for maximum load at failure strength (BPTB=620.8+/-209 N vs. SBC=601.2+/-140 N, p=0.74) or stiffness (BPTB=69.8 N/mm+/-29 N/mm vs SBC=47.1+/-31.6 N/mm, p=0.24). The SBC allograft yielded significantly more displacement prior to failure than the BPTB graft (15.1+/-4.9 mm vs 9.2+/-1.3 mm, p=0.04). Increased construct displacement appeared to be due to fixation failure, with some evidence of graft tissue tearing around the sutures: Bioabsorbable screw (10 x 28 mm) fixation of the SBC allograft produced unacceptable displacement levels during testing. Further study is recommended using a titanium interference screw or a longer bioabsorbable screw for SBC graft fixation under cyclic loading conditions.
authors.affiliation: Department of Orthopaedic Surgery, Frazier Rehabilitation Institute, Suite 1003, University of Louisville, 210 East Gray Street, Louisville, KY 40202, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Kocabey
authors.forename: S
authors.initials: S
authors.lastname: Klein
authors.forename: J
authors.initials: J
authors.lastname: Nyland
authors.forename: D
authors.initials: D
authors.lastname: Caborn
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000502:physiology; D001863:Bone Screws; D002102:Cadaver; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D010329:Patella / Q000601:surgery; D013314:Stress, Mechanical; D013710:Tendons / Q000637:transplantation*; D013718:Tensile Strength / Q000502:physiology; D013977:Tibia / Q000601:surgery*; D014025:Titanium; D014184:Transplantation, Homologous
chemical_list: D014025:Titanium