Polymorphisms in the estrogen receptor beta gene and risk of breast cancer: no association.
Polymorphisms in the estrogen receptor beta (ERbeta) gene may influence the cellular growth regulating effects of estradiol. In this first association study about breast cancer risk and polymorphisms in the ERbeta gene we have screened 219 Finnish sporadic breast cancer cases and 248 ethnically matched male controls. No difference in the allele distribution of the six studied polymorphisms was found between the breast cancer and control groups.
Försti
Asta
A
Department of Biosciences at Novum, Karolinska Institute, Huddinge, Sweden. asta.forsti@cnt.ki.se
Zhao
Chunyan
C
Israelsson
Elisabeth
E
Dahlman-Wright
Karin
K
Gustafsson
Jan-Ake
JA
Hemminki
Kari
K
D001943:Breast Neoplasms / Q000209:etiology* / Q000235:genetics*; D016022:Case-Control Studies; D002455:Cell Division; D047629:Estrogen Receptor beta; D005260:Female; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011960:Receptors, Estrogen / Q000235:genetics*; D012307:Risk Factors
D047629:Estrogen Receptor beta; D011960:Receptors, Estrogen