[Preoperative superselective intra-internal iliac arterial chemotherapy for invasive bladder cancer and curative analysis].
OBJECTIVE
To study clinical effects of preoperative intra-internal iliac-arterial chemotherapy for invasive bladder cancer.


METHODS
14 cases of invasive bladder cancer underwent superselective intra-internal iliac-arterial chemotherapy before conservative cystectomy.


RESULTS
After 2-3 week therapy, reduction of cancer volume (20%-50%), clotted by thrombus in the blood vessels of the cancer or circumferential tissue, and decreased bleeding were found. Pathomorphological features included large patchy necrosis, degeneration, and inflammatory changes of carcinoma tissue. Follow-up ranged from 5 to 42 months (mean 19.6 months). One T3 N1 M0) of the cases (0.7%) relapsed into T1N0M0 and the others did not.


CONCLUSIONS
The intra-internal iliac-arterial method, simple, safe, coordinates in pre-operation for invasive bladder cancer, and increases the operative opportunity for preservation of functional bladder.
Deng
X
X
Department of Urology, Dalian Friendship Hospital, China.
Wu
Y
Y
Jiang
Y
Y
Cong
P
P
Li
S
S
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000601:surgery / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D015653:Cystectomy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery / Q000628:therapy*