title: The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode.
abstract: The sequelae of Infectious Intestinal Disease (IID) in a population-based sample of cases and matched controls were investigated for a period of 3 months following the initial infection. Incident cases of IID presenting to GPs or occurring in the community and controls were studied at 3 weeks and over a 3-month follow-up period. Cases were six times more likely than controls to have gastrointestinal symptoms, particularly diarrhoea, at 3 weeks. Ten per cent of cases consulted their GP in the 3 months after episode and 2.3% were referred to hospital. GP presentation rates were twice as high in cases. Gastrointestinal symptoms persist after IID, leading to an increased likelihood of GP consultation and hospital referral. Diagnosis of irritable bowel syndrome may be more likely following IID. The burden of IID is likely to be considerable given its high incidence and the frequency of such sequelae.
authors.affiliation: London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
authors.forename: P
authors.initials: P
authors.lastname: Cumberland
authors.forename: D
authors.initials: D
authors.lastname: Sethi
authors.forename: P J
authors.initials: PJ
authors.lastname: Roderick
authors.forename: J G
authors.initials: JG
authors.lastname: Wheeler
authors.forename: J M
authors.initials: JM
authors.lastname: Cowden
authors.forename: J A
authors.initials: JA
authors.lastname: Roberts
authors.forename: L C
authors.initials: LC
authors.lastname: Rodrigues
authors.forename: M J
authors.initials: MJ
authors.lastname: Hudson
authors.forename: D S
authors.initials: DS
authors.lastname: Tompkins
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002662:Child Health Services / Q000706:statistics & numerical data*; D002675:Child, Preschool; D003141:Communicable Diseases / Q000453:epidemiology*; D004739:England / Q000453:epidemiology; D005194:Family Practice / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007410:Intestinal Diseases / Q000453:epidemiology*; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D012017:Referral and Consultation; D012044:Regression Analysis