title: [Formaldehyde exposure levels and exposure control measures during an anatomy dissecting course].
abstract: The evaporation of formaldehyde from cadavers can produce high exposures among students and instructors. A possible causal role for formaldehyde has been considered likely for tumor of the nasopharynx and the nasal cavities in human beings. Due to this reason, Japan Ministry of Education, Culture, Sports, Science and Technology (MEXT) has set a guideline, which includes--decrease in gaseous formaldehyde in gross anatomy dissection laboratories and a guide to medical students about the toxicity of formaldehyde and protective method to avoid damages to skin, mucous, membrane, etc, in 2002. To understand what effective plans should be regarding the awareness of students about this notification, this study measured the gaseous formaldehyde concentrations in the anatomy dissection room and also analyzed the formaldehyde-related symptoms, and frequency of using protective measures. The study was conducted over a period of 3 months during the anatomy dissection exercise. We found that immediately after removing the cadavers' plastic covering, formaldehyde concentrations in the dissection room increased sharply. The concentration reached a peak point of 0.62 ppm after 10 minutes of starting of the class. This was much above the recommended level of 0.5 ppm set by Japan Society for Occupational Health. After 30 minutes of achieving the peak the formaldehyde level started decreasing gradually to a level of 0.11 ppm. Formaldehyde-related symptoms were observed in 59% of students. They had experienced symptoms of irritation of eyes, nose, throat, airways, skin, and headache during the course. Ocular discomfort was found significantly higher in the contact lenses users compared to the spectacle users or the normal eye sight group. Although, the guidelines about toxicity of formaldehyde and its protective measures to prevent damages to skin, mucous membrane etc. were informed to every student, only 52% of the students used both the mask containing activated carbon and the rubber gloves in every practical class without fail. Environmental Health Criteria 89 of International Program of Chemical Safety states, "It must be regarded that formaldehyde fluid is not absorbed directly into tissues through the skin". So the students may be allowed in some cases to touch the cadaver, treated by formaldehyde content fixative, by bare hands to understand the feel of certain organs and tissues. These results support that the rules of health supervision including necessity to use of protective measures, monitoring of indoor air formaldehyde etc. should be adhered by students and instructors in anatomy dissection room during the practical class.
authors.affiliation: Department of Preventive Medicine, School of Medicine, Fukushima Medical University, Japan.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Tanaka
authors.forename: Keiji
authors.initials: K
authors.lastname: Nishiyama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yaginuma
authors.forename: Akihiko
authors.initials: A
authors.lastname: Sasaki
authors.forename: Takahumi
authors.initials: T
authors.lastname: Maeda
authors.forename: Sin-ya
authors.initials: SY
authors.lastname: Kaneko
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Onami
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Tanaka
mesh_terms: D016902:Air Pollution, Indoor / Q000009:adverse effects* / Q000032:analysis*; D000715:Anatomy; D002102:Cadaver; D003261:Contact Lenses; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects* / Q000032:analysis* / Q000633:toxicity; D006801:Humans; D007753:Laboratories; D008297:Male; D008452:Maximum Allowable Concentration; D011482:Protective Devices / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D005557:Formaldehyde