De novo pulmonary capillary hemangiomatosis occurring rapidly after bilateral lung transplantation.
A 45-year-old woman experienced diffuse bilateral pulmonary capillary hemangiomatosis within 3 months after bilateral lung transplantation. The donor was a 41-year-old man with excellent lung function and without histologic or macroscopic pulmonary lesions at the time of retrieval. This case supports the theory that persistent infection or inflammation may be an inciting factor in uncontrolled angiogenesis, leading ultimately to diffuse pulmonary capillary hemangiomatosis.
de Perrot
Marc
M
Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Waddell
Thomas K
TK
Chamberlain
Dean
D
Hutcheon
Michael
M
Keshavjee
Shaf
S
D000328:Adult; D001706:Biopsy; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D018324:Hemangioma, Capillary / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D008175:Lung Neoplasms / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D016040:Lung Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D011552:Pseudomonas Infections / Q000150:complications / Q000382:microbiology / Q000473:pathology; D011550:Pseudomonas aeruginosa; D014797:Vital Capacity / Q000502:physiology