title: Retention of dye after indocyanine Green-assisted internal limiting membrane peeling.
abstract: OBJECTIVE
  To describe the long-term retention of indocyanine green (ICG) in the fundus after ICG-assisted internal limiting membrane peeling.
  
  
  METHODS
  Case report. Two patients underwent vitrectomy including ICG-assisted internal limiting membrane peeling. The fundus was examined with a 780-nm infrared illumination of a scanning laser ophthalmoscope after surgery.
  
  
  RESULTS
  No ICG staining of the fundus was visible ophthalmoscopically. Examination with a scanning laser ophthalmoscope, however, detected fluorescence from residual ICG until 6 months after surgery in case 1 and 9 months in case 2. No complication related to the residual ICG was observed.
  
  
  CONCLUSIONS
  The results suggested that ICG remains in the fundus for a long period after surgery. Clearance of the dye from the diabetic retina may be prolonged.
authors.affiliation: Department of Ophthalmology, Nagoya City University Medical School, Nagoya, Japan. ma-kou@t-gh.bias.ne.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ashikari
authors.forename: Hironori
authors.initials: H
authors.lastname: Ozeki
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Tomida
authors.forename: Eiji
authors.initials: E
authors.lastname: Sakurai
authors.forename: Kazushi
authors.initials: K
authors.lastname: Tamai
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ogura
mesh_terms: D000368:Aged; D004396:Coloring Agents / Q000493:pharmacokinetics*; D019773:Epiretinal Membrane / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D005453:Fluorescence; D006801:Humans; D007208:Indocyanine Green / Q000493:pharmacokinetics*; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012160:Retina / Q000378:metabolism*; D012167:Retinal Perforations / Q000601:surgery; D014821:Vitrectomy
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green