Pediatric cardiopulmonary-cerebral resuscitation: an overview and future directions.
The evolving understanding of pathophysiologic events during and after pediatric cardiac arrest has not yet resulted in significantly improved outcome. Exciting breakthroughs in basic and applied science laboratories are, however, on the immediate horizon for study in specific subpopulations of cardiac arrest victims. Strategically focusing therapies to specific phases of cardiac arrest and resuscitation and evolving pathophysiologic events offers great promise that critical care interventions will lead the way to more successful cardiopulmonary and cerebral resuscitation in children.
Morris
Marilyn C
MC
Department of Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA.
Nadkarni
Vinay M
VM
D000818:Animals; D016887:Cardiopulmonary Resuscitation / Q000379:methods* / Q000639:trends; D002560:Cerebrovascular Circulation; D006323:Heart Arrest / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology / Q000628:therapy*; D010372:Pediatrics