title: Phenyl ethers from cultured lichen mycobionts of Graphis scripta var. serpentina and G. rikuzensis.
abstract: Spore-derived mycobionts of the lichen Graphis scripta var. serpentina and G. rikuzensis were cultivated on a malt-yeast extract medium supplemented with 10% sucrose and their metabolites were investigated. 3,3'-Dihydroxy-5,5'-dimethyldiphenyl ether was isolated from the cultures of the mycobionts of G. scripta var. serpentina, while a new phenyl ether, rikuzenol, along with two known diphenyl ethers, violaceol-I and violaceol-II, were isolated from those of G. rikuzensis. The structure of the new compound was determined by spectroscopic methods. Violaceol-I was chemically synthesized and interconversion between violaceol-I and violaceol-II was proven.
authors.affiliation: Kobe Pharmaceutical University, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Takenaka
authors.forename: Takao
authors.initials: T
authors.lastname: Tanahashi
authors.forename: Naotaka
authors.initials: N
authors.lastname: Nagakura
authors.forename: Nobuo
authors.initials: N
authors.lastname: Hamada
mesh_terms: D008011:Lichens / Q000302:isolation & purification*; D010647:Phenyl Ethers / Q000737:chemistry* / Q000302:isolation & purification*; D024301:Plant Bark; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D010647:Phenyl Ethers; D010936:Plant Extracts