Gene therapy in the treatment of intestinal inflammation.
BACKGROUND
Local expression of anti-inflammatory or immunoregulatory genes may offer an alternative treatment of gastrointestinal inflammation.


CONCLUSIONS
We review the basic requirements for gene therapy, the possible routes of delivery, and the different strategies for specific targeting focusing on gastrointestinal inflammation.
van Montfrans
Catherine
C
Department of Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
te Velde
Anje A
AA
van Deventer
Sander J H
SJ
Rodriguez Pena
Maria Sol
MS
D005759:Gastroenteritis / Q000628:therapy*; D018390:Gene Targeting; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D006801:Humans; D014158:Transcription, Genetic