title: Association of vitamin D receptor gene polymorphism with periodontal diseases in Japanese and Chinese.
abstract: We examined whether polymorphisms in the vitamin D receptor (VDR) gene are associated with the incidence of adult periodontitis (AP) and early-onset periodontitis (EOP) in case-controlled studies of Japanese and Chinese subjects. Restriction fragment length polymorphisms in the VDR gene detected by digestion with Taq I were found to be significantly associated with the occurrence of AP or EOP, suggesting that the VDR genotype a risk factor for periodontitis.
authors.affiliation: Department of Pharmacology, Osaka Dental University.
authors.forename: Y
authors.initials: Y
authors.lastname: Tachi
authors.forename: H
authors.initials: H
authors.lastname: Shimpuku
authors.forename: Y
authors.initials: Y
authors.lastname: Nosaka
authors.forename: T
authors.initials: T
authors.lastname: Kawamura
authors.forename: M
authors.initials: M
authors.lastname: Shinohara
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: H
authors.initials: H
authors.lastname: Imai
authors.forename: K
authors.initials: K
authors.lastname: Ohura
authors.forename: J
authors.initials: J
authors.lastname: Sun
authors.forename: H
authors.initials: H
authors.lastname: Meng
authors.forename: C
authors.initials: C
authors.lastname: Cao
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002681:China; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000235:genetics*; D011110:Polymorphism, Genetic; D018167:Receptors, Calcitriol / Q000235:genetics*
chemical_list: D018167:Receptors, Calcitriol