title: [Most common cases of the unreasonable medication use].
abstract: Doctors prescribing some medications together are often using unreasonable drug combinations. The rationality of prescribing the medications by means of case-records and computerized data base of the state sicknes fund was investigated. The article addresses the most common cases of unreasonable use of medications, which could be divided into five subgroups: 1) Prescribing drug combinations, that increase the possibility of side-effects; 2) Prescribing some medications, that may suppress the effects of each other together; 3) Using medications, that belong to the same group together; 4) Prescribing the medications either without indication or out of indication; 5) Other cases of the unreasonable medication use. This article discusses the risk of using most common drug combinations and provides recommendations that could help to prevent unreasonable medication use.
authors.affiliation: Department of the Basic and Clinical Pharmacology, Kaunas University of Medicine, A. Mickeviciaus 9, 3000 Kaunas, Lithuania.
authors.forename: Gintautas
authors.initials: G
authors.lastname: Gumbrevicius
authors.forename: Arvydas
authors.initials: A
authors.lastname: Milasius
mesh_terms: D000368:Aged; D004336:Drug Antagonism; D004347:Drug Interactions; D011307:Drug Prescriptions; D004357:Drug Synergism; D004358:Drug Therapy; D004359:Drug Therapy, Combination; D004363:Drug Utilization; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D019338:Polypharmacy