title: Comparison of stereotactic fine needle aspiration cytology and core needle biopsy in 522 non-palpable breast lesions.
abstract: OBJECTIVE
  To compare the accuracy of stereotactic fine needle aspiration cytologies (S-FNAC) and stereotactic core needle biopsies (S-CNB) in non-palpable breast lesions.
  
  
  METHODS
  Between May 1993 and December 2000, 696 patients with mammographically detected lesions were biopsied both with S-FNAC and S-CNB. S-FNAC was performed with spinal needle 22- or 20-gauge and S-CNB with an automated 14-gauge gun.
  
  
  RESULTS
  Of the 696 patients, 522 (75%) underwent breast surgery with postoperative histopathology. In all, 448 of these 522 women (86%) had malignant and 74 (14%) had benign lesions. S-FNAC revealed cancer in 254 (57%) and probable cancer in 48 (11%) (sensitivity 68%, specificity 99.6%) and S-CNB revealed cancer in 388 (87%) and probable cancer in 18 (4%) (sensitivity 90%, specificity 98.8%) of these 448 patients.
  
  
  CONCLUSIONS
  S-CNB was more accurate than S-FNAC in the diagnosis of non-palpable breast cancer.
authors.affiliation: Department of Radiology, St. Göran Hospital Inc., Stockholm, Sweden. karin.leifland@capio.se
authors.forename: K
authors.initials: K
authors.lastname: Leifland
authors.forename: U
authors.initials: U
authors.lastname: Lagerstedt
authors.forename: G
authors.initials: G
authors.lastname: Svane
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D012680:Sensitivity and Specificity; D013048:Specimen Handling