[Malaria: state of art].
Some actual aspects of malaria are here described. After an outline of the actual epidemiological situation of malaria endemic in the world and some historical reports on Italian malaria phenomena before the institution of malaria control measures, chemoprophylaxis and its more problematic aspects, mainly related to multiresistant drug Plasmodium falciparum strains, are discussed in the first part. In the second part the factors potentially implicated in a reintroduction of malaria in free areas are analyzed; with a special reference to climatic changes. Finally the more recent vaccine perspectives are summarized; the authors discuss the principal experiences made using synthetic peptides of different plasmodial origin.
Morelli
G
G
V Divisione-Ospedale Specializzato per Malattie Infettive, AO Monadi-Cotugno, Napoli.
Amoroso
P
P