title: [Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult].
abstract: During neurosurgery for hypophysary adenoma under general anaesthesia in a prone position, a 34 year-old-women received accidental 6 ml intramucosal injection of lidocaine with naphazoline. The patient presented a severe bradycardia associated with a major increase in arterial blood pression followed by a brief cardiac arrest. She also presented a prolonged awakening and a pulmonary oedema, which lead to mechanical ventilation. The patient rapidly recovered a normal clinical state.
authors.affiliation: Département d'anesthésie et de réanimation chirurgicale, centre hospitalier régional, hôpital de La Source, 45000, Orléans, France. isabellevilleret@wanadoo.fr <isabellevilleret@wanadoo.fr>
authors.forename: I
authors.initials: I
authors.lastname: Villeret
authors.forename: A C
authors.initials: AC
authors.lastname: Tellier
authors.forename: S
authors.initials: S
authors.lastname: Erhmann
authors.forename: D
authors.initials: D
authors.lastname: Réa
authors.forename: J P
authors.initials: JP
authors.lastname: Delalande
mesh_terms: D000236:Adenoma / Q000601:surgery; D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D000768:Anesthesia, General; D000779:Anesthetics, Local; D001794:Blood Pressure / Q000187:drug effects; D001919:Bradycardia / Q000139:chemically induced; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D008012:Lidocaine; D019300:Medical Errors; D009278:Naphazoline / Q000008:administration & dosage / Q000009:adverse effects*; D010911:Pituitary Neoplasms / Q000601:surgery; D011654:Pulmonary Edema / Q000139:chemically induced*
chemical_list: D000316:Adrenergic alpha-Agonists; D000779:Anesthetics, Local; D008012:Lidocaine; D009278:Naphazoline