[Multiple sebaceous tumors with colon cancer--Muir-Torre syndrome].
The Muri-Torre syndrome is an autosomal-dominant genodermatosis. The criteria of the diagnosis is the occurrence of at least one sebaceous skin tumour and at least one malignant internal tumour. Skin tumours must be considered as very important signs because they may precede visceral malignancies. The authors present the case of a 62 years old man. Three tumours were excised from three different locations of his trunk in the Plastic Surgery Ward of our hospital. The tumours proved to be sebaceous adenoma, sebaceous epithelioma and sebaceous carcinoma by histology. Because of this result, we had conducted a detailed tumour screening which found a non-symptomatic malformation of the proximal colon tract. Histology of the resected colon part revealed adenocarcinoma. With the presentation of this case the authors call attention on the fact, that in case of the diagnosis of a sebaceous skin tumour, careful tumour screening could be lifesaving.
Vajda
Adrienne
A
Bórgyógyászati Osztály és Rendelóintézet, Magyar Honvédség Központi Honvédkórház, Budapest.
Scharrer
Krisztina
K
Baló-Banga
J Mátyás
JM
D018266:Adenocarcinoma, Sebaceous / Q000209:etiology* / Q000235:genetics / Q000473:pathology*; D003110:Colonic Neoplasms / Q000150:complications* / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics / Q000473:pathology*; D012626:Sebaceous Gland Neoplasms / Q000209:etiology* / Q000235:genetics / Q000473:pathology*