The effects of electromagnetic field on distraction osteogenesis.
The effects of electromagnetic field on distraction osteogenesis and new bony tissue were investigated. Twenty-five New Zealand rabbits were divided into an experimental (12 rabbits) and a control (13 rabbits) group. An osteotomy was performed on the right tibia in the diaphyseal region in both groups. The experimental group was exposed to a magnetic field of 50 Hz 1.0 mT for 3 hours a day for 13 weeks. The control group was kept in a similar environment but with no electromagnetic field. The distraction was continued until an increase of 10 mm was achieved. At weeks 4, 8, and 13, radiography, scintigraphy, and a biopsy were performed in both groups, and the results were statistically analyzed. The X-ray results were similar in both groups at all times. On the other hand while the scintigraphic and histopathological results were similar at weeks 4 and 13 in both groups, the osteoblastic activity was significantly greater in the experimental group at week 8 (p < 0.01). In conclusion an electromagnetic field increases the osteoblastic activity and osteogenesis, but has little effect during the remodeling phase.
Kesemenli
Cumhur Cevdet
CC
Department of Orthopedic and Traumatology, School of Medicine, Dicle University, Diyarbakir, Turkey. ccevdet@dicle.edu.tr
Subasi
Mehmet
M
Kaya
Halil
H
Sert
Cemil
C
Büyükbayram
Huseyin
H
Arslan
Hüseyin
H
Necmioglu
Serdar
S
D000818:Animals; D004574:Electromagnetic Fields; D010006:Osteoblasts / Q000502:physiology / Q000528:radiation effects; D010012:Osteogenesis / Q000528:radiation effects; D019857:Osteogenesis, Distraction; D010027:Osteotomy; D011817:Rabbits