20 years of Ins(1,4,5)P3, and 40 years before.
This year marks the 20th birthday of the discovery of inositol-1,4,5-trisphosphate as a second messenger. The background to this discovery is a complex story that goes back more than 50 years and involves a large cast of characters, both chemical and human.
Irvine
Robin F
RF
Department of Pharmacology, Tennis Court Road, Cambridge CB2 1QJ, UK. rfi20@cam.ac.uk
D049673:History, 20th Century; D015544:Inositol 1,4,5-Trisphosphate / Q000266:history*
D015544:Inositol 1,4,5-Trisphosphate