title: Gene therapy in the treatment of intestinal inflammation.
abstract: BACKGROUND
  Local expression of anti-inflammatory or immunoregulatory genes may offer an alternative treatment of gastrointestinal inflammation.
  
  
  CONCLUSIONS
  We review the basic requirements for gene therapy, the possible routes of delivery, and the different strategies for specific targeting focusing on gastrointestinal inflammation.
authors.affiliation: Department of Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
authors.forename: Catherine
authors.initials: C
authors.lastname: van Montfrans
authors.forename: Anje A
authors.initials: AA
authors.lastname: te Velde
authors.forename: Sander J H
authors.initials: SJ
authors.lastname: van Deventer
authors.forename: Maria Sol
authors.initials: MS
authors.lastname: Rodriguez Pena
mesh_terms: D005759:Gastroenteritis / Q000628:therapy*; D018390:Gene Targeting; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D006801:Humans; D014158:Transcription, Genetic