A new cationic, chiral catalyst for highly enantioselective Diels-Alder reactions.
[reaction: see text] The Diels-Alder reaction of cyclopentadiene and 2-methacrolein is catalyzed by a chiral Lewis acid to form the exo adduct in 96% yield and 96% ee.
Sprott
Kevin T
KT
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Corey
E J
EJ
D002384:Catalysis; D002412:Cations / Q000737:chemistry*; D013237:Stereoisomerism
D002412:Cations