Correlation of trace mineral concentrations with fructose, gamma-glutamyl transpeptidase, and acid phosphatase in seminal plasma of different categories of infertile men.
The study describes the concentrations of zinc, magnesium, copper, iron, and biochemical markers of seminal vesicle and prostate in seminal plasma of different categories of infertile men. The zinc level in oligasthenospermic subjects was significantly higher than in azoospermic, asthenospermic, and oligospermic subjects. The gamma-glutamyl transpeptidase activity in both oligoasthenospermic and azoospermic subjects were significantly lower than in asthenospermic and oligospermic individuals. There was no significant difference in iron, copper, and magnesium levels and acid phosphatase activity among the different infertile categories. A positive correlation between zinc and acid phosphatase (r=0.84, r= 0.73; p < 0.05), and between copper and fructose (r=0.81, r=0.72; p<0.05) was observed in oligoasthenospermic and azoospermic men, respectively. On the basis of our results, it may be postulated that there is a direct effect of the trace elements zinc and copper on acid phosphatase and fructose, respectively, in oligoasthenospermic and azoospermic subjects.
Pant
Niraj
N
Analytical Chemistry Section, Industrial Toxicology Research Centre, Post Box 80, MG Marg, Lucknow-226001, India.
Srivastava
S P
SP
D000135:Acid Phosphatase / Q000378:metabolism*; D000328:Adult; D015415:Biomarkers / Q000032:analysis; D005632:Fructose / Q000032:analysis*; D006801:Humans; D007246:Infertility / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D012661:Semen / Q000737:chemistry*; D014131:Trace Elements / Q000032:analysis*; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D015415:Biomarkers; D014131:Trace Elements; D005632:Fructose; D005723:gamma-Glutamyltransferase; D000135:Acid Phosphatase