title: The relationship between five kinds of laparoscopic knots and five types of suture materials and histological findings in tissues: an experimental study on rabbits.
abstract: The aim of the current study was to examine the slipping and the tightening of laparoscopic knots with various kinds of sutures, as well as the histologic alterations in tissues. Fifty rabbits and five kinds of sutures were used-silk, polyglactine-910 (Vicryl), Polydioxanone (PDS), Polyglycol (Dexon), and cat-gut chromic-and five laparoscopic knots were used-Tayside, Roeder, Melzer, Cross, and Blood. The knots were performed extracorporeally and were used to ligate a part of the omentum. Sliding and tightening of the knots were evaluated. The omentum, the suture, and the knots were checked 10 days and 1 month after operation. Histologic examination was performed 1 month after surgery. Polyglactine-910 (Vicryl) and silk were the most qualitative sutures used in Tayside, Roeder, and Blood knots and the least harmful for the tissues. Catgut chromic and Polydioxanone (PDS) were the most defective sutures. The most efficient laparoscopic slipknots are Tayside, Roeder, and Blood, especially when constructed with silk and polyglactine-910 (Vicryl).
authors.affiliation: First Surgical Department, Red Cross Hospital, Athens, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Patsalos
authors.forename: Dionysios
authors.initials: D
authors.lastname: Karavias
authors.forename: Michail
authors.initials: M
authors.lastname: Stavropoulos
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tierris
authors.forename: George
authors.initials: G
authors.lastname: Bablekos
authors.forename: Irene
authors.initials: I
authors.lastname: Nicolaou
authors.forename: Ioannis
authors.initials: I
authors.lastname: Androulakis
mesh_terms: D000818:Animals; D002398:Catgut / Q000009:adverse effects*; D004195:Disease Models, Animal; D019476:Insect Proteins / Q000009:adverse effects / Q000494:pharmacology*; D010535:Laparoscopy / Q000009:adverse effects*; D009852:Omentum / Q000187:drug effects* / Q000473:pathology* / Q000601:surgery; D016687:Polydioxanone / Q000009:adverse effects / Q000494:pharmacology*; D011098:Polyglactin 910 / Q000009:adverse effects / Q000494:pharmacology*; D011100:Polyglycolic Acid / Q000009:adverse effects / Q000494:pharmacology*; D011183:Postoperative Complications; D011817:Rabbits; D015203:Reproducibility of Results; D047011:Silk; D013536:Suture Techniques / Q000009:adverse effects*; D013537:Sutures / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D019476:Insect Proteins; D047011:Silk; D011100:Polyglycolic Acid; D016687:Polydioxanone; D011098:Polyglactin 910