title: [Effects of infrasound on visual electrophysiology in mice].
abstract: OBJECTIVE
  To investigate the possible effects of infrasound on visual functions.
  
  
  METHODS
  One hundred and fifty mature male Kunming-mice were divided into 5 groups, in which one was control and the other four were exposed to infrasound of 8 Hz, 90 dB; 8 Hz, 130 dB; 16 Hz, 90 dB and 16 Hz, 130 dB 2 h/d respectively. The exposure time for them were 0, 1, 4, 7, 14 and 21 d respectively, each group was divided into 6 sub-groups. Electroretinogram (ERG), oscillatory potentials (OPs), and visual evoked potential (VEP) were recorded after exposure.
  
  
  RESULTS
  The visual electrophysiological indices after 8 Hz, 90 dB and 16 Hz, 90 dB exposures were similar except for a little difference at some temporal points (P<0.05). Most of the indices in 8 Hz, 130 dB group changed after 7 d exposure, and the longer the exposure, the more obvious changes were observed (P<0.01). The indices in 16 Hz, 130 dB group changed obviously after 1 d and reversed with increase of exposure time (P<0.01).
  
  
  CONCLUSIONS
  The effect of infrasound on visual functions are related to its frequency and intensity. Infrasound of different frequencies causes different levels of retinal resonance, which leads to different degrees of cellular lesion and produces different electrical potentials.
authors.affiliation: Department of Clinical Aerospace Medicine, The Fourth Military Medical University, Xi'an, China.
authors.forename: Li
authors.initials: L
authors.lastname: Shi
authors.forename: Zuo-ming
authors.initials: ZM
authors.lastname: Zhang
authors.forename: Jing-zao
authors.initials: JZ
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D004594:Electrophysiology; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011571:Psychoacoustics; D012160:Retina / Q000502:physiology*; D013016:Sound; D014785:Vision, Ocular / Q000502:physiology*