[Levels of some cytokines in infants with central nervous system damage].
Two cytokines--interleukin 1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) levels have been studied in infants with CNS damage of different severity. The more was the brain lesion severity, the higher the TNF-alpha level increased. IL-1 beta levels were reduced significantly in severe brain injury caused by hypoxia. Chronic hypoxia combined with intrauterine infection and/or a risk of the latter was accompanied by imbalance of IL-1 beta and TNF-alpha secretion.
Autenshlius
A I
AI
Shkunov
A N
AN
Ivanova
O V
OV
Degtiareva
V G
VG
Mikhaĭlova
E S
ES
D000208:Acute Disease; D001424:Bacterial Infections / Q000150:complications / Q000382:microbiology; D002908:Chronic Disease; D016207:Cytokines / Q000276:immunology* / Q000378:metabolism*; D005315:Fetal Diseases / Q000382:microbiology; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications / Q000276:immunology*; D007223:Infant; D007231:Infant, Newborn; D007375:Interleukin-1 / Q000276:immunology / Q000378:metabolism; D012720:Severity of Illness Index; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology / Q000378:metabolism
D016207:Cytokines; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha