[Use of chromato-mass-spectrometry for the differential diagnosis of suppurative and nonsuppurative inflammations in the maxillofacial area in children].
Ten children with inflammatory processes in the maxillofacial soft tissues and 10 healthy children were examined using chromato-mass-spectrometry of the chemical composition of oral cavity air. Air samples were collected by an adsorbent sample collector by individual sucking and analyzed on a Finnigan MAT chromato-mass-spectrometer. The concentrations of short-chain fatty acids and minor ketones were increased and normally absent isobutyl alcohol appeared in the oral cavity air in patients with serous inflammations. The content of valeraldehyde, isoprene, sulfur compounds increased significantly in suppurative inflammations; ramified long-chain aldehydes, absent in serous inflammation, appeared. The ratios of the following substance concentrations were estimated: acetaldehyde/valeraldehyde, pentane/dimethylsulfide, undecane/dimethylsulfide, which can be used for the differential diagnosis of suppurative and nonsuppurative inflammations of the maxillofacial soft tissues in children.
Volozhin
A I
AI
Aleshina
O E
OE
Rogonskiĭ
V V
VV
D002481:Cellulitis / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D005145:Face; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D008199:Lymphadenitis / Q000175:diagnosis*; D009333:Neck; D018461:Soft Tissue Infections / Q000175:diagnosis*