Are thiazide diuretics preferred as first-line therapy for hypertension? An appraisal of The Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Scott
I
I
Department of Internal Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia. ian.scott@health.qld.gov.au
Stowasser
M
M
D000368:Aged; D017311:Amlodipine / Q000627:therapeutic use; D001581:Benzothiadiazines; D001774:Blood Chemical Analysis; D002752:Chlorthalidone / Q000627:therapeutic use; D004232:Diuretics; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D017379:Hypertrophy, Left Ventricular / Q000517:prevention & control; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D017706:Lisinopril / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000517:prevention & control*; D011793:Queensland; D012016:Reference Values; D018570:Risk Assessment; D012720:Severity of Illness Index; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use*; D020521:Stroke / Q000517:prevention & control; D016019:Survival Analysis; D016896:Treatment Outcome
D001581:Benzothiadiazines; D004232:Diuretics; D000960:Hypolipidemic Agents; D049993:Sodium Chloride Symporter Inhibitors; D017311:Amlodipine; D017706:Lisinopril; D002752:Chlorthalidone