Opsoclonus: an early sign of neonatal herpes encephalitis.
Preferential involvement of certain central nervous systems areas by specific viruses provides a valuable guide to the selection of antiviral agents. We report a neonate that developed opsoclonus 7 days prior to the diagnosis of herpes simplex type 2 cerebellitis. The course of the opsoclonus paralleled the clinical course and radiologic evolution of the infection. The purpose of this report is to describe opsoclonus as a possible early sign of herpes simplex type 2 central nervous system infection.
Krolczyk
Stanley
S
Department of Neurology, Cleveland Clinic, Weston, Florida, USA.
Pacheco
Esperanza
E
Valencia
Pablo
P
Papazian
Oscar
O
Yelin
Karina
K
Alfonso
Israel
I
D002531:Cerebellum / Q000473:pathology* / Q000821:virology*; D020803:Encephalitis, Herpes Simplex / Q000150:complications* / Q000175:diagnosis; D005260:Female; D018258:Herpesvirus 2, Human / Q000472:pathogenicity*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008279:Magnetic Resonance Imaging; D015835:Ocular Motility Disorders / Q000209:etiology*; D014057:Tomography, X-Ray Computed