title: Strain variation among Bordetella pertussis isolates from Québec and Alberta provinces of Canada from 1985 to 1994.
abstract: Pulsed-field gel electrophoresis and gene typing were able to differentiate among 3,597 Bordetella pertussis isolates circulating in Alberta and Québec Provinces, Canada, from 1985 to 1994 and distinguish them from the strains used in vaccine production. This study provides a baseline for continued surveillance of prevalent and emerging strains of B. pertussis in Canada.
authors.affiliation: Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada. mark.peppler@ualberta.ca
authors.forename: Mark S
authors.initials: MS
authors.lastname: Peppler
authors.forename: Sharee
authors.initials: S
authors.lastname: Kuny
authors.forename: Anna
authors.initials: A
authors.lastname: Nevesinjac
authors.forename: Christina
authors.initials: C
authors.lastname: Rogers
authors.forename: Yvon R
authors.initials: YR
authors.lastname: de Moissac
authors.forename: Kathleen
authors.initials: K
authors.lastname: Knowles
authors.forename: Manon
authors.initials: M
authors.lastname: Lorange
authors.forename: Gaston
authors.initials: G
authors.lastname: De Serres
authors.forename: James
authors.initials: J
authors.lastname: Talbot
mesh_terms: D000416:Alberta / Q000453:epidemiology; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001886:Bordetella pertussis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D014644:Genetic Variation; D006801:Humans; D037342:Pertussis Toxin / Q000235:genetics; D010567:Pertussis Vaccine; D011792:Quebec / Q000453:epidemiology; D010566:Virulence Factors, Bordetella / Q000235:genetics; D014917:Whooping Cough / Q000453:epidemiology / Q000382:microbiology
chemical_list: D001425:Bacterial Outer Membrane Proteins; D010567:Pertussis Vaccine; D010566:Virulence Factors, Bordetella; C068929:pertactin; D037342:Pertussis Toxin