title: [Mycetomas in central Tunisia].
abstract: BACKGROUND
  Mycetomas are inflammatory pseudo-tumors containing fungal or actinomycosic-type grains. They are frequent in tropical and subtropical countries and unknown in Tunisia.
  
  
  METHODS
  We conducted a retrospective study of 12 cases of mycetoma registered in the Dermatological department of the university hospital in Sousse (central Tunisia) over a period of 27 years, from 1974 to 2001. The diagnosis was confirmed by anatomopathological and/or mycological examination.
  
  
  RESULTS
  The mean age at the onset was of 49 years and the sex ratio of 1. A notion of a traumatism was reported in two cases and eight patients had various agricultural activities. The mean duration of progression was of eight years. The localization was the foot in 10 cases. The mycetoma was of actinomycosic origin in 10 cases, due to Actinomadura madurae in nine cases, to Nocardia spp in one case and of fungal origin in 2 cases:Pseudoallescheria boydii in one case and Madurella mycetomi in the other. Antibiotic therapy was associated with surgical exeresis in nine cases and amputation in the other two cases.
  
  
  CONCLUSIONS
  Confrontation of our results with those of Tunisian series and a review of the literature, helped to specify the clinico-epidemiological characteristics and progression of mycetoma in Tunisia. These characteristics are: the rareness of the infection, the relative frequency of affection in women, the proximal involvement of the foot, the frequency of agricultural activity and the rareness of traumatic past history, the predominance of the actinomycosic origin due to Actinomadura madurae, and the need to associate surgical exeresis with the medical treatment or amputation in order to stop the progress of the disease.
authors.affiliation: Service de Dermatologie, CHU Farhat Hached, 4002 Sousse, Tunisie. dr.denguezli@topnet.tn
authors.forename: M
authors.initials: M
authors.lastname: Denguezli
authors.forename: M
authors.initials: M
authors.lastname: Kourda
authors.forename: N
authors.initials: N
authors.lastname: Ghariani
authors.forename: C
authors.initials: C
authors.lastname: Belajouza
authors.forename: B
authors.initials: B
authors.lastname: Mokni
authors.forename: F
authors.initials: F
authors.lastname: Chebil
authors.forename: B
authors.initials: B
authors.lastname: Riahi
authors.forename: B
authors.initials: B
authors.lastname: Jomaa
authors.forename: R
authors.initials: R
authors.lastname: Nouira
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D000383:Agriculture; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D014416:Tunisia
chemical_list: D000900:Anti-Bacterial Agents