Pigmented squamous cell carcinoma of the uterine cervix.
A 57-year-old female presented with an abnormal Pap smear. Colposcopic examination of the cervix revealed white mucosa with erosion and several areas of black pigmentation. After a colposcopically directed biopsy and loop conization, radical hysterectomy and bilateral salpingo-oophorectomy with pelvic and paraaortic lymphadenectomy were performed. Pathological examination disclosed an invasive squamous cell carcinoma admixed with many dendritic melanocytes. Melanin granules were present within the melanocytes and tumor cells. Although similar tumors have been reported in other sites, this is the first report to our knowledge of a pigmented squamous cell carcinoma of the uterine cervix.
Masuzawa
Naoko
N
Department of Pathalogy, Otsu Municipal Hospital, Otsu, Japan.
Kishimoto
Mitsuo
M
Takahashi
Yoshiki
Y
D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002467:Cell Nucleus / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology* / Q000601:surgery; D003127:Colposcopy; D019092:Conization; D003593:Cytoplasm / Q000473:pathology; D003713:Dendritic Cells / Q000473:pathology; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008543:Melanins / Q000032:analysis; D008544:Melanocytes / Q000473:pathology; D008854:Microscopy, Electron; D008875:Middle Aged; D010052:Ovariectomy; D065006:Papanicolaou Test; D010858:Pigmentation; D014626:Vaginal Smears
D008543:Melanins