title: Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.
abstract: The new nematicidal compound, betagamma-dehydrocurvularin (1), together with three known compounds, alphabeta-dehydrocurvularin (2), 8-beta-hydroxy-7-oxocurvularin (3) and 7-oxocurvularin (4), were isolated from the culture filtrate and mycelial mats of Aspergillus sp. The structures of 1-4 were established by spectroscopic methods including 2D NMR. The biological activities of 1-4 were examined by bioassays with root-lesion nematodes, and lettuce and rice seedlings.
authors.affiliation: Umea Plant Science Centre, Department of Forest Genetics and Plant Physiology, The Swedish University of Agricultural Sciences, SE 901 83 Umea, Sweden.
authors.forename: Miyako
authors.initials: M
authors.lastname: Kusano
authors.forename: Kazumi
authors.initials: K
authors.lastname: Nakagami
authors.forename: Shozo
authors.initials: S
authors.lastname: Fujioka
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kawano
authors.forename: Atsumi
authors.initials: A
authors.lastname: Shimada
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kimura
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D010935:Plant Diseases / Q000469:parasitology; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D036226:Seedlings / Q000187:drug effects; D013057:Spectrum Analysis; D014431:Tylenchoidea / Q000187:drug effects*; D015025:Zearalenone / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000969:Antinematodal Agents; D015025:Zearalenone; C013455:curvularin