Studies on a heterologous complex formed by human butyrylcholinesterase.
An electrophoretic band with butyrylcholinesterase activity was detected in 71 CHE2 C5+ and 378 CHE2 C5- individuals and was named C4/5 in view of its similar mobility to either C4 or C5, depending on the pH of the agar gel used. The present data suggest that C4/5 is a heterologous complex of butyrylcholinesterase. Although the C4/5 band may have the same mobility as C5, depending on the conditions of electrophoresis, our hypothesis is that these two bands result from the association of BChE with different molecules.
Souza
R L R
RL
Department of Genetics, Federal University of Paraná, PO Box 19071, 81531-990 Curitiba, PR, Brazil.
Furtado
L
L
Diniz
A C P
AC
Silva
A C D
AC
Kaiss
J
J
Petzl-Erler
M L
ML
Chautard-Freire-Maia
E A
EA
D002091:Butyrylcholinesterase / Q000097:blood / Q000737:chemistry* / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010641:Phenotype; D012462:Saline Solution, Hypertonic / Q000494:pharmacology
D012462:Saline Solution, Hypertonic; D002091:Butyrylcholinesterase