title: [Barotherapy in cerebrovascular diseases].
abstract: It has been shown that the main problem of treating patients with cerebral ischemia using minimal excessive pressures is the choice of the optimum therapeutic dose. We propose a new method of treatment for cerebral vascular disorders with an application for minimum high pressure doses (< 1.1 ata with oxygen a air mixture). The aim of the present report is to summarize clinical results of this method and to estimate the mechanisms of its action. The main feature of the method described (barotherapy) is to bring external and cell respiration and recovery of oxygen autoregulation of cell respiration to normal values in patients with increased CO2 inner production. The administration of antioxidants transporting electrons on mitochondrial respiratory chain significantly improves the clinical outcome after barotherapy and leads to stabilization of lipid peroxidation.
authors.forename: N V
authors.initials: NV
authors.lastname: Kazantseva
authors.forename: E I
authors.initials: EI
authors.lastname: Gusev
authors.forename: L D
authors.initials: LD
authors.lastname: Makarova
authors.forename: E B
authors.initials: EB
authors.lastname: Petukhov
mesh_terms: D002561:Cerebrovascular Disorders / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*