New taxane diterpenoids from Taiwanese Taxus sumatrana.
Two new taxane diterpenoids, tasumatrols A (1) and B (2), have been isolated from extracts of the leaves and twigs of Taiwanese Taxus sumatrana. Tasumatrol A is a rare 5/6/6 taxene system, having a novel gamma-lactone at C-10 and C-19. The structures of compounds 1 and 2 were determined on the basis of two dimensional (2D)-NMR techniques, including correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC) and heteronuclear multiple bond connectivity (HMBC) experiments.
Shen
Ya-Ching
YC
Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China. ycshen@mail.nsysu.edu.tw
Pan
Yu-Ling
YL
Lo
Kuang-Liang
KL
Wang
Shih-Sheng
SS
Chang
Yao-To
YT
Wang
Li-Tang
LT
Lin
Yu-Chi
YC
D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves; D018547:Plant Stems; D013624:Taiwan; D043823:Taxoids / Q000737:chemistry / Q000302:isolation & purification*; D020946:Taxus
D001952:Bridged-Ring Compounds; D004224:Diterpenes; D010936:Plant Extracts; D043823:Taxoids; C080625:taxane