Changing prevalent T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients in Japan.
We surveyed T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients. T1 (emm1) remained dominant through 1992 to 2000, but the dominant T3 (emm3.1) strains from 1992 to 1995 disappeared during 1996-2000. Strains of several emm genotypes emerged during 1996-2000, indicating alterations in the prevalent strains causing TSLS.
Ikebe
T
T
Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
Murai
N
N
Endo
M
M
Okuno
R
R
Murayama
S
S
Saitoh
K
K
Yamai
S
S
Suzuki
R
R
Isobe
J
J
Tanaka
D
D
Katsukawa
C
C
Tamaru
A
A
Katayama
A
A
Fujinaga
Y
Y
Hoashi
K
K
Ishikawa
J
J
Watanabe
H
H
D000942:Antigens, Bacterial / Q000235:genetics*; D005838:Genotype; D006801:Humans; D007564:Japan / Q000453:epidemiology; D015995:Prevalence; D012772:Shock, Septic / Q000453:epidemiology* / Q000382:microbiology; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification* / Q000276:immunology
D000942:Antigens, Bacterial