title: Maternal respiratory syncytial virus antibody titers: season and children matter.
abstract: The seasonal variation in concentrations of maternal serum antibodies to respiratory syncytial virus fusion protein was investigated with the use of 761 maternal sera at delivery of term infants during a 12-month period. Mean antibody titers were significantly higher between April and September and significantly higher in women who already had children at home.
authors.affiliation: Division of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
authors.forename: Nicole
authors.initials: N
authors.lastname: Le Saux
authors.forename: Isabelle
authors.initials: I
authors.lastname: Gaboury
authors.forename: Noni
authors.initials: N
authors.lastname: MacDonald
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D008431:Maternal-Fetal Exchange / Q000502:physiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011256:Pregnancy Outcome; D011336:Probability; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000635:transmission*; D012136:Respiratory Syncytial Viruses / Q000276:immunology*; D012307:Risk Factors; D012621:Seasons
chemical_list: D000914:Antibodies, Viral