title: Immunopathogenesis and immunotherapy in AIDS virus infections.
abstract: The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of infected individuals have posed challenges to understanding the pathogenesis of HIV infection. But continuing advances in our knowledge of the role of immune responses in controlling HIV viremia should help to define goals for immune-based therapies and vaccine strategies against AIDS.
authors.affiliation: Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
authors.forename: Norman L
authors.initials: NL
authors.lastname: Letvin
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Walker
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000628:therapy*; D000906:Antibodies / Q000276:immunology; D015658:HIV Infections / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology* / Q000472:pathogenicity*; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000821:virology
chemical_list: D000906:Antibodies; D006680:HLA Antigens