title: Yersinia pestis TonB: role in iron, heme, and hemoprotein utilization.
abstract: In Yersinia pestis, the siderophore-dependent yersiniabactin (Ybt) iron transport system and heme transport system (Hmu) have putative TonB-dependent outer membrane receptors. Here we demonstrate that hemin uptake and iron utilization from Ybt are TonB dependent. However, the Yfe iron and manganese transport system does not require TonB.
authors.affiliation: Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, Kentucky 40536-8994, USA. rperry@pop.uky.edu
authors.forename: Robert D
authors.initials: RD
authors.lastname: Perry
authors.forename: Jessica
authors.initials: J
authors.lastname: Shah
authors.forename: Scott W
authors.initials: SW
authors.lastname: Bearden
authors.forename: Jan M
authors.initials: JM
authors.lastname: Thompson
authors.forename: Jacqueline D
authors.initials: JD
authors.lastname: Fetherston
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D029968:Escherichia coli Proteins / Q000235:genetics; D006418:Heme / Q000378:metabolism*; D006420:Hemeproteins / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D021381:Protein Transport
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; C052874:ExbB protein, E coli; C447836:HasB protein, Serratia marcescens; D006420:Hemeproteins; D008565:Membrane Proteins; C057616:tonB protein, Bacteria; C489181:tonB protein, E coli; C060790:exbD protein, E coli; D006418:Heme; D007501:Iron