title: Intrapericardial chemotherapy for the management of neoplastic cardiac tamponade.
abstract: A young patient with disseminated osteogenic sarcoma presented with cardiac tamponade. She was successfully managed with pericardiocentesis and intrapericardial instillation of cisplatin. There was no reaccumulation of pericardial fluid or recurrence of tamponade until the patient's death 12 months later. Intrapericardial chemotherapy may be effective in the management of cardiac tamponade secondary to malignancy.
authors.affiliation: Department of Medicine, College of Medicine, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. neelamsiddiqui@hotmail.com
authors.forename: Neelam
authors.initials: N
authors.lastname: Siddiqui
authors.forename: Abdulrahman I
authors.initials: AI
authors.lastname: Al-Diab
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002305:Cardiac Tamponade / Q000188:drug therapy* / Q000209:etiology; D002945:Cisplatin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000209:etiology*; D020519:Pericardiocentesis; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin