[Heterotopic gray matter. Report of four pediatric cases].
Severe infant epilepsy is included within difficult etiologic diagnosis. Gray matter heterotopias are an uncommon cause. The authors report four observations of gray matter heteropias concerning three-, six-, seven- and nine-year-old girls, presenting no particular antecedents. No consanguinity was noted. The first occurrence of epilepsy ranged from the age of nine months to the age of four years. A mild mental retardation was found in three cases, and mental regression in one case. A status epilepticus was noted in three children. Magnetic resonance imaging scans showed subependymal heterotopias in one case and diffuse cortical heterotopias in three cases associated to a partial agenesis of corpus calloseum in one case and pachygyria in two cases.
Mrad
S Mazigh
SM
Service de pédiatrie générale, hôpital d'enfants de Tunis, 1007 Jebbari, bab Saadoun, Tunis, Tunisie. sonia.mrad@rns.tn
Aloui
N
N
Ben Jeddou
A
A
Fetni
I
I
Oubich
F
F
Boukthir
S
S
Hammou
A
A
Barsaoui
S
S
D001927:Brain Diseases / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000150:complications*; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging