The experimental study on mixed culture of osteoblasts and tricalcium phosphate ceramics in vitro.
To study the effects of tricalcium phosphate (TCP) ceramics on osteoblasts, the rat osteoblasts were cultured with the TCP ceramics in vitro. Scanning electron microscopy and the colorimetric methyl-thiazol-tetrazolium assay showed that the osteoblasts could adhere well to the surface of the ceramics and the culture dish, and the proliferation of the cells was not inhibited. The results demonstrated that TCP ceramics possessed an excellent cytocompatibility with the osteoblasts, and had some promoting effects on proliferation of osteoblasts.
Zeng
H
H
Department of Orthopedics, Xiehe Hospital, Tongji Medical University, Wuhan 430022.
Du
J
J
Zheng
Q
Q
Liu
Y
Y
Guo
X
X
D000818:Animals; D000831:Animals, Newborn; D001672:Biocompatible Materials / Q000494:pharmacology*; D002130:Calcium Phosphates / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D010006:Osteoblasts / Q000166:cytology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D023822:Tissue Engineering
D001672:Biocompatible Materials; D002130:Calcium Phosphates; D017077:Culture Media, Conditioned; C485817:beta-tricalcium phosphate; C018392:tricalcium phosphate