title: Yeast gene expression during growth at low temperature.
abstract: Gene expression during growth at low temperature in the yeast Saccharomyces cerevisiae was investigated by means of DNA microarray analysis. A large number of genes showed an increase or decrease in expression at 4 degrees C relative to 25 degrees C. Although a temperature shift was not performed, differential expression of the cold shock genes TIP1, TIR1, TIR2, and NSR1 was observed. These genes may be necessary for growth at temperatures as low as 4 degrees C as well as for adapting to rapid drops in temperature. A new class of genes, many with unknown functions, was found to be induced during growth at low temperature. We propose to call these genes "low temperature growth genes."
authors.affiliation: International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6, 1-1, Higashi 1-chome, Tsukuba-shi, Ibaraki-ken 305-8566, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Homma
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Iwahashi
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Komatsu
mesh_terms: D003080:Cold Temperature; D005656:Fungal Proteins / Q000235:genetics; D015870:Gene Expression; D020869:Gene Expression Profiling; D006360:Heat-Shock Proteins / Q000235:genetics; D006358:Hot Temperature; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000254:growth & development*; D012769:Shock / Q000378:metabolism; D014199:Trehalose / Q000235:genetics
chemical_list: D005656:Fungal Proteins; D006360:Heat-Shock Proteins; D014199:Trehalose