Distribution of three arbovirus antibodies among monkeys (Macaca fascicularis) in the Philippines.
Serum samples from 54 monkeys were collected from healthy individuals in a monkey farm in Luzon island, Philippines, in 1999, and examined by IgM-capture ELISA and indirect IgG ELISA for the presence of dengue (DEN), Japanese encephalitis (JE) and chikungunya (CHIK) viruses. The positive rates for IgM ELISA were 3.7, 35.2 and 14.8% against DEN, JE and CHIK, respectively. Higher positive rates were obtained when indirect IgG ELISA was used: 100% against flaviviruses (JE or DEN) and 59.3% against CHIK virus. The results indicate a high prevalence of flavivirus infections such as JE and DEN, and a lesser prevalence of CHIK virus infections, among monkeys in the Philippines. These findings suggest possible sylvatic transmission cycles of these viruses.
Inoue
S
S
Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki City, Nagasaki 852-8523, Japan. pampanga@net.nagasaki-u.ac.jp
Morita
K
K
Matias
R R
RR
Tuplano
J V
JV
Resuello
R R G
RR
Candelario
J R
JR
Cruz
D J M
DJ
Mapua
C A
CA
Hasebe
F
F
Igarashi
A
A
Natividad
F F
FF
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001102:Arbovirus Infections / Q000453:epidemiology / Q000276:immunology*; D001103:Arboviruses / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D008252:Macaca fascicularis / Q000276:immunology* / Q000821:virology*; D008297:Male; D008992:Monkey Diseases / Q000453:epidemiology / Q000276:immunology / Q000821:virology; D010679:Philippines / Q000453:epidemiology
D000914:Antibodies, Viral