title: Integrated assessment of preclinical data: shifting high attrition rates to earlier phase drug development.
authors.forename: Cees
authors.initials: C
authors.lastname: Korstanje
mesh_terms: D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods* / Q000592:standards / Q000639:trends; D006801:Humans; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000592:standards / Q000639:trends