title: EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissues.
abstract: A significant population of expressed sequence tags (ESTs) encodes chimeric transcripts containing microRNA (miRNA) precursor sequences as well as pieces of adjacent mRNAs in sense orientation. These chimeric transcripts may potentially be involved in miRNA biosynthesis, and/or affect expression of adjacent mammalian mRNAs.
authors.forename: Neil R
authors.initials: NR
authors.lastname: Smalheiser
mesh_terms: D000818:Animals; D020224:Expressed Sequence Tags; D006801:Humans; D051379:Mice; D035683:MicroRNAs / Q000096:biosynthesis / Q000235:genetics*; D008969:Molecular Sequence Data; D012322:RNA Precursors / Q000096:biosynthesis / Q000235:genetics*; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics*; D051381:Rats; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
chemical_list: D035683:MicroRNAs; D012322:RNA Precursors; D012333:RNA, Messenger