title: [The clinical evaluation of Oratest in detecting oral mucosal lesions].
abstract: OBJECTIVE
  The aim of the study was to evaluate the clinical efficacy of Oratest in detecting oral mucosal lesions.
  
  
  METHODS
  Sixty patients with oral mucosal lesions that were suspected as carcinoma or premalignant lesions were divided into two groups randomly. The lesions were stained with Oratest by topical application in one group and rinse application in another group. Staining results were recorded and compared with the pathological diagnosis.
  
  
  RESULTS
  The sensitivity of Oratest stain to oral carcinoma and dysplasia were 93.9% and 42.9%, respectively. The difference between rinse application and local application showed no significance(P > 0.01).
  
  
  CONCLUSIONS
  Oratest can be used as a method of diagnosing squamous cell carcinoma of oral mucosa, but its reliability in screening oral pre-malignant lesions is still uncertain.
authors.affiliation: College of Stomatology, Sun Yat-sen University, Guangzhou 510060, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Cheng
authors.forename: Linglan
authors.initials: L
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D002648:Child; D004396:Coloring Agents; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis*; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*; D013194:Staining and Labeling; D014048:Tolonium Chloride
chemical_list: D004396:Coloring Agents; D014048:Tolonium Chloride