title: [Reciprocal relation of proliferative activity in central and peripheral zones of splenic organ culture exposed to vilon in rats of various ages].
abstract: There was studied in spleen organotypic tissue culture the effect of vilon on the development of of proliferative activity in central and peripheral fields of explants of rats of various age: 3 days, 3 weeks and 2 years old. Vilon stimulated cell proliferation both in young and old rats, in spite of all there are reciprocal relations of this process in central and peripheral fields in the spleen organotypic culture of rats of various age.
authors.affiliation: St. Petersburg Institute of Bioregulation and Gerontology of the North-Western Branch, Russian Academy of Medical Sciences, 3, Dinamo Prospect, 197110 St. Petersburg, Russia.
authors.forename: N M
authors.initials: NM
authors.lastname: Bykov
authors.forename: N I
authors.initials: NI
authors.lastname: Chalisova
authors.forename: P N
authors.initials: PN
authors.lastname: Zeziulin
mesh_terms: D000367:Age Factors; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004151:Dipeptides / Q000494:pharmacology*; D066298:In Vitro Techniques; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000166:cytology / Q000187:drug effects*
chemical_list: D004151:Dipeptides; C415909:lysylglutamic acid