[Studies on the lignan chemical constituents from pine needles of Pinus massoniana Lamb].
OBJECTIVE
To study the chemical constituents of the pine needles from Pinus massoniana Lamb..


METHODS
Various chromatographic techniques were used for the separation and purification. The physicochemical properties and spectral data were used to elucidate the structures.


RESULTS
Three compounds were isolated from the n-BuOH fraction of water-extracts. The structures were identified as (7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside (massonianoside D, 7), 4,4',9,9'-tetrahydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan ((+)-isolariciresinol, 8) and 4,4',9'-trihydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan-9-O-beta-D- xylopyranoside (isolariciresinol-9-O-xyloside, 9) on the basis of spectral data (ORD, UV, IR, MS, 1HNMR, 13CNMR, 1H-1HCOSY, HMQC and HMBC etc.).


CONCLUSIONS
Compound 7 is a new compound, while compounds 8 and 9 were isolated from this plant for the first time.
Feng
Wei-sheng
WS
Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. fwsh@371.net
Bi
Yue-feng
YF
Zheng
Xiao-ke
XK
Wang
Xin-liang
XL
Li
Jun
J
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D008031:Lignin / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D009005:Monosaccharides / Q000737:chemistry / Q000302:isolation & purification*; D009284:Naphthols / Q000737:chemistry / Q000302:isolation & purification; D028223:Pinus / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
C483807:(7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside; D004365:Drugs, Chinese Herbal; D017705:Lignans; D009005:Monosaccharides; D009284:Naphthols; C060284:isolariciresinol; D008031:Lignin