title: Effects of glass ionomer sealants in newly erupted first molars after 5 years: a pilot study.
abstract: OBJECTIVE
  The aim of the study was to investigate the caries-preventive effect of high-filled glass ionomer sealant in newly erupted first molars in a high-risk group. This investigation is part of a larger study amongst eight hundred and thirty-five 6-7-year-old Syrian children.
  
  
  METHODS
  Children that had 1, 2 or 3 just erupted or erupting and at least one unerupted first molar (control) were enrolled in this pilot study. A total of 60 children fulfilled the inclusion criteria. There were 49 children with a total of 83 sealants available for examination at the evaluation year 5.
  
  
  RESULTS
  Almost two out of the three sealants (69%) had disappeared between evaluation years 2 and 3. 1.2% (SE = 1.2) of the sealants survived were fully retained and 10.3% (SE = 3.3) of the sealants survived were fully and partially retained at the evaluation year 5. Caries prevalence of the children in the study group at the evaluation year 5 was 55%. The Odds ratio concerning sealed and control group at year 5 was 2.6 with 95% confidence limits of 1.2 and 5.7, implying a relative risk (RR) of 2.1. Unsealed unerupted first molars had 2.1 times higher chance than sealed newly erupted first molars to develop dentinal lesions in this child population after 5 years.
  
  
  CONCLUSIONS
  It is concluded that sealing newly erupted first molars with high-filled glass ionomer may be a caries-preventive measure in high-risk children. However, a well-designed clinical trial should be implemented to confirm the initial findings.
authors.affiliation: Regional WHO Demonstration, Training and Research Centre for Oral Health, Damascus, Syria.
authors.forename: Dia
authors.initials: D
authors.lastname: Taifour
authors.forename: Jo E
authors.initials: JE
authors.lastname: Frencken
authors.forename: Martin A
authors.initials: MA
authors.lastname: van't Hof
authors.forename: Nabil
authors.initials: N
authors.lastname: Beiruti
authors.forename: Gert-Jan
authors.initials: GJ
authors.lastname: Truin
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D003731:Dental Caries / Q000453:epidemiology / Q000517:prevention & control*; D003804:Dentin; D005260:Female; D005899:Glass Ionomer Cements / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008963:Molar; D016017:Odds Ratio; D010865:Pilot Projects; D010895:Pit and Fissure Sealants; D015995:Prevalence; D013593:Syria / Q000453:epidemiology; D035862:Vulnerable Populations
chemical_list: D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants