title: Eosinophilic heart: marked left ventricular wall thickening and myocardial dysfunction improving with corticosteroid therapy.
abstract: We report a case of a 34-year-old male with acute severe heart failure associated with marked concentric left ventricular wall thickening and biopsy evidence of eosinophilic myocardial infiltrate. This appears to be an unusual description of this degree of concentric myocardial thickening in eosinophilic myocarditis coupled with Doppler tissue echocardiography. Following high-dose corticosteroid treatment, wall thickness, systolic and diastolic left ventricular function normalized and the patient experienced a dramatic clinical improvement.
authors.affiliation: St. Andrew's Heart Institute, Brisbane, Qld, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Adsett
authors.forename: Malcolm J
authors.initials: MJ
authors.lastname: West
authors.forename: Andrew
authors.initials: A
authors.lastname: Galbraith
authors.forename: Edwina
authors.initials: E
authors.lastname: Duhig
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Lange
authors.forename: Przemyslaw
authors.initials: P
authors.lastname: Palka
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D015150:Echocardiography, Doppler; D004802:Eosinophilia / Q000150:complications / Q000188:drug therapy*; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D009206:Myocardium / Q000473:pathology*; D020257:Ventricular Remodeling / Q000502:physiology*
chemical_list: D000305:Adrenal Cortex Hormones