Giant cell arteritis.
Giant cell arteritis is the most common vasculitis in Caucasians. The aetiology of this disease remains uncertain. This article reviews some of the recent work in epidemiology and pathology in this field, with particular regard to the immunohistochemical findings in temporal artery biopsy specimens. The possible correlation between clinical features and biopsy specimen histology is discussed, and a model of pathogenesis is presented.
Penn
Henry
H
Department of Rheumatology, Southend General Hospital, Prittlewell Chase, Essex SS00RY, Westcliff-on-Sea, UK.
Dasgupta
Bhaskar
B
D013700:Giant Cell Arteritis / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D006261:Headache / Q000503:physiopathology; D006801:Humans