title: Synthetic approaches toward ecteinascidins. Part 2. Preparation of the ABCDE ring system of ecteinascidins having characteristic substituents in both benzene rings.
abstract: A synthesis of an advanced ABCDE ring system (24c) having characteristic substituents in both benzene rings of ecteinascidin marine natural products is described based on our model studies.
authors.affiliation: Meiji Pharmaceutical University, Kiyose, Japan. naoki@my-pharm.ac.jp
authors.forename: Naoki
authors.initials: N
authors.lastname: Saito
authors.forename: Ryu-ichi
authors.initials: R
authors.lastname: Seki
authors.forename: Noriko
authors.initials: N
authors.lastname: Kameyama
authors.forename: Rie
authors.initials: R
authors.lastname: Sugimoto
authors.forename: Akinori
authors.initials: A
authors.lastname: Kubo
mesh_terms: D001554:Benzene / Q000138:chemical synthesis*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis*; D007546:Isoquinolines; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D007546:Isoquinolines; C464992:ecteinascidin 770; D001554:Benzene