title: Efficient synthesis of enynecarbamates and their ring-closing metathesis/[4 + 2] Diels-Alder cycloaddition: synthesis of hexahydroisoquinolines.
abstract: Enynes 5a-g were prepared in moderate to good yields from 1-(triphenylphosphoranylideneaminoalkyl)benzotriazoles. Ring-closing metathesis of 5a-f afforded functionalized dienes 6a-f, respectively, which were used in a Diels-Alder cycloaddition reaction in the synthesis of the corresponding hexahydroisoquinoline derivatives 7a-f.
authors.affiliation: Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Satheesh K
authors.initials: SK
authors.lastname: Nair
authors.forename: Tatyana
authors.initials: T
authors.lastname: Khokhlova
authors.forename: Novruz G
authors.initials: NG
authors.lastname: Akhmedov