title: Pigmented squamous cell carcinoma of the uterine cervix.
abstract: A 57-year-old female presented with an abnormal Pap smear. Colposcopic examination of the cervix revealed white mucosa with erosion and several areas of black pigmentation. After a colposcopically directed biopsy and loop conization, radical hysterectomy and bilateral salpingo-oophorectomy with pelvic and paraaortic lymphadenectomy were performed. Pathological examination disclosed an invasive squamous cell carcinoma admixed with many dendritic melanocytes. Melanin granules were present within the melanocytes and tumor cells. Although similar tumors have been reported in other sites, this is the first report to our knowledge of a pigmented squamous cell carcinoma of the uterine cervix.
authors.affiliation: Department of Pathalogy, Otsu Municipal Hospital, Otsu, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Masuzawa
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kishimoto
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Takahashi
mesh_terms: D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002467:Cell Nucleus / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology* / Q000601:surgery; D003127:Colposcopy; D019092:Conization; D003593:Cytoplasm / Q000473:pathology; D003713:Dendritic Cells / Q000473:pathology; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008543:Melanins / Q000032:analysis; D008544:Melanocytes / Q000473:pathology; D008854:Microscopy, Electron; D008875:Middle Aged; D010052:Ovariectomy; D065006:Papanicolaou Test; D010858:Pigmentation; D014626:Vaginal Smears
chemical_list: D008543:Melanins