Synthetic approaches toward ecteinascidins. Part 2. Preparation of the ABCDE ring system of ecteinascidins having characteristic substituents in both benzene rings.
A synthesis of an advanced ABCDE ring system (24c) having characteristic substituents in both benzene rings of ecteinascidin marine natural products is described based on our model studies.
Saito
Naoki
N
Meiji Pharmaceutical University, Kiyose, Japan. naoki@my-pharm.ac.jp
Seki
Ryu-ichi
R
Kameyama
Noriko
N
Sugimoto
Rie
R
Kubo
Akinori
A
D001554:Benzene / Q000138:chemical synthesis*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis*; D007546:Isoquinolines; D013678:Technology, Pharmaceutical / Q000379:methods*
D006576:Heterocyclic Compounds, 4 or More Rings; D007546:Isoquinolines; C464992:ecteinascidin 770; D001554:Benzene