The action of the herbicide 2,4-dichlorophenoxyacetic acid on the isolated sciatic nerve of the frog (Rana ridibunda).
The isolated sciatic nerve of the frog was used to assess the effects of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) on the peripheral nervous system. For each experiment, both sciatic nerves were used. The evoked compound action potentials of the nerves were monitored for over 48 h as an indication of their viability. The viability of nerve incubated in control saline was compared to the viability of the nerve incubated in saline where 2,4-D was diluted. The minimum effective concentration (minEC) of 2,4-D was estimated to be between 2 and 4 mM.
Kouri
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G
Laboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University, Thessaloniki 54006, Greek Macedonia, Hellas, Greece. theophil@bio.auth.gr
Theophilidis
G
G