title: [Intracytoplasmic injection with sperm from ejaculation, epididymis and testis in treating different male infertility with oligo-asthenozoospermia or azoospermia ].
abstract: OBJECTIVE
  To retrospectively study 400 intracytoplasmic sperm injection (ICSI) cycles by using three different sources of sperm.
  
  
  METHODS
  Different male infertility with oligo-asthenozoospermia or azoospermia was treated by ICSI using sperm from ejaculation, epididymis and testis.
  
  
  RESULTS
  In the ejaculation group (n = 277), the fertilization rate was 69.6% and the clinical pregnancy rate 28.9%. In the 104 cycles using epididymal sperm, the fertilization and clinical pregnancy rate was 65.9% and 37.5% respectively. And the fertilization and clinical pregnancy of testis sperm (n = 19) was 65.7% and 21.1%. The difference of fertilization and clinical pregnancy rate among the three groups were not significant.
  
  
  CONCLUSIONS
  Male infertility of different causes can be treated by ICSI. The outcome has nothing to do with the common parameter of semen except that the sperm motility is 0, but the effectiveness of ICSI should be studied by long-term observation.
authors.affiliation: Genesiology Research Center, First Clinical Hospital, Zhongshan Medical University, Guangzhou, China.
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.forename: G
authors.initials: G
authors.lastname: Zhuang
authors.forename: R
authors.initials: R
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Zhou
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Xu
authors.forename: H
authors.initials: H
authors.lastname: Mei
mesh_terms: D000328:Adult; D053713:Azoospermia / Q000150:complications*; D004542:Ejaculation; D004822:Epididymis / Q000166:cytology; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000628:therapy*; D008297:Male; D009845:Oligospermia / Q000150:complications*; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D013737:Testis / Q000166:cytology; D016896:Treatment Outcome; D055815:Young Adult