title: A more convenient and general procedure for O-monobenzylation of diols via stannylenes: a critical reevaluation of the Bu2SnO method.
abstract: A more consistent, straightforward, and economical protocol for generation of stannylene species and their reaction with BnBr leading to products of O-monobenzylation of diols has been set. It has shown to be specially indicated for substrates bearing vicinal trans 1,2-diol moieties on cyclohexane backbones, which are more resistant to these transformations. Such protocol has been successfully applied to myo-inositol derivatives and acyclic diols.
authors.affiliation: Universidade Federal do Rio de Janeiro, Núcleo de Pesquisas de Produtos Naturais (NPPN), Laboratório Roderick A. Barnes, Ilha da Cidade Universitária, CCS, bloco H, Rio de Janeiro RJ 21941-590, Brazil. abcsimas@nppn.ufrj.br
authors.forename: Alessandro B C
authors.initials: AB
authors.lastname: Simas
authors.forename: Karla C
authors.initials: KC
authors.lastname: Pais
authors.forename: Angelo A T
authors.initials: AA
authors.lastname: da Silva