title: An unusual oxidative cyclization: studies towards the biomimetic synthesis of pyridomacrolidin.
abstract: An unusual oxidative cyclization of a N-hydroxy pyridone 9 with Z-2-cyclodecenone 11 has been achieved, thus demonstrating a possible biomimetic route to pyridomacrolidin 2. [reaction: see text]
authors.affiliation: Dyson Perrins Laboratory, Department of Chemistry, Oxford University, South Parks Road, Oxford OX1 3QY, United Kingdom.
authors.forename: Nageswara Rao
authors.initials: NR
authors.lastname: Irlapati
authors.forename: Jack E
authors.initials: JE
authors.lastname: Baldwin
authors.forename: Robert M
authors.initials: RM
authors.lastname: Adlington
authors.forename: Gareth J
authors.initials: GJ
authors.lastname: Pritchard
authors.forename: Andrew
authors.initials: A
authors.lastname: Cowley
mesh_terms: D032701:Biomimetics; D003500:Cyclization; D007659:Ketones / Q000737:chemistry; D010084:Oxidation-Reduction; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007659:Ketones; D011728:Pyridones; C114117:pyridomacrolidin