title: 20 years of Ins(1,4,5)P3, and 40 years before.
abstract: This year marks the 20th birthday of the discovery of inositol-1,4,5-trisphosphate as a second messenger. The background to this discovery is a complex story that goes back more than 50 years and involves a large cast of characters, both chemical and human.
authors.affiliation: Department of Pharmacology, Tennis Court Road, Cambridge CB2 1QJ, UK. rfi20@cam.ac.uk
authors.forename: Robin F
authors.initials: RF
authors.lastname: Irvine
mesh_terms: D049673:History, 20th Century; D015544:Inositol 1,4,5-Trisphosphate / Q000266:history*
chemical_list: D015544:Inositol 1,4,5-Trisphosphate