Strain variation among Bordetella pertussis isolates from Québec and Alberta provinces of Canada from 1985 to 1994.
Pulsed-field gel electrophoresis and gene typing were able to differentiate among 3,597 Bordetella pertussis isolates circulating in Alberta and Québec Provinces, Canada, from 1985 to 1994 and distinguish them from the strains used in vaccine production. This study provides a baseline for continued surveillance of prevalent and emerging strains of B. pertussis in Canada.
Peppler
Mark S
MS
Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada. mark.peppler@ualberta.ca
Kuny
Sharee
S
Nevesinjac
Anna
A
Rogers
Christina
C
de Moissac
Yvon R
YR
Knowles
Kathleen
K
Lorange
Manon
M
De Serres
Gaston
G
Talbot
James
J
D000416:Alberta / Q000453:epidemiology; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001886:Bordetella pertussis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D014644:Genetic Variation; D006801:Humans; D037342:Pertussis Toxin / Q000235:genetics; D010567:Pertussis Vaccine; D011792:Quebec / Q000453:epidemiology; D010566:Virulence Factors, Bordetella / Q000235:genetics; D014917:Whooping Cough / Q000453:epidemiology / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins; D010567:Pertussis Vaccine; D010566:Virulence Factors, Bordetella; C068929:pertactin; D037342:Pertussis Toxin