title: Persistent perianal abscess in early infancy as a presentation of autoimmune neutropenia.
abstract: Autoimmune neutropenia of infancy is a primary, usually self-limiting, antineutrophil autoimmune phenomenon seen in infancy and early childhood. These infants are at a higher risk of infection, and early detection, particularly with the availability of newer therapeutic options such as hematopoietic growth factors, can allow close follow-up and, if needed, treatment. We report two infants with autoimmune neutropenia who presented with a persistent perianal abscess, which has not been documented previously in this population.
authors.affiliation: Department of Pediatrics, University of South Florida College of Medicine and All Children's Hospital, St Petersburg, FL 31020, USA.
authors.forename: Marisa
authors.initials: M
authors.lastname: Lejkowski
authors.forename: Akhil
authors.initials: A
authors.lastname: Maheshwari
authors.forename: Darlene A
authors.initials: DA
authors.lastname: Calhoun
authors.forename: Robert D
authors.initials: RD
authors.lastname: Christensen
authors.forename: Suzanne
authors.initials: S
authors.lastname: Skoda-Smith
authors.forename: Sharon
authors.initials: S
authors.lastname: Dabrow
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000276:immunology; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000008:administration & dosage; D001004:Anus Diseases / Q000175:diagnosis* / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009503:Neutropenia / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D011994:Recombinant Proteins; D012008:Recurrence; D018570:Risk Assessment
chemical_list: D001323:Autoantibodies; D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor; D019980:Amoxicillin-Potassium Clavulanate Combination