title: Predictive value of pulse oximetry and fetal scalp blood pH in the case of meconium-stained amniotic fluid.
abstract: OBJECTIVE
  To compare the predictive value of intrapartum fetal pulse oximetry to that of fetal scalp blood pH for an abnormal neonatal outcome in the case of thick meconium.
  
  
  METHODS
  A prospective multicenter observational study was performed from June 1994 to November 1995. Fetal oxygen saturation was monitored using a Nellcor N-400 fetal pulse oximeter in case of abnormal FHR. The last readings of fetal oxygen saturation and fetal scalp blood pH before birth were used to assess the ability of both techniques to predict an abnormal neonatal status.
  
  
  RESULTS
  At a 30% cutoff, the negative predictive value of fetal oxygen saturation was not altered in case of meconium when compared to clear amniotic fluid (79 and 83%, respectively). Fetal scalp blood pH at a 7.20 threshold had a poor negative predictive value in case of meconium when compared to clear amniotic fluid (56% versus 88%, respectively). The receiver operator characteristic curve showed similar performance of fetal scalp blood pH and pulse oximetry in cases with clear amniotic fluid. In cases with meconium, the performance of fetal scalp blood pH was poor, whereas that of pulse oximetry remained unchanged. In three cases with meconium below the vocal cords, a drop in fetal oxygen saturation was observed during labor whereas fetal scalp blood pH remained within normal values.
  
  
  CONCLUSIONS
  The predictive value of fetal scalp blood pH is poor in case of meconium, whereas the predictive value of pulse oximetry seems to be unchanged in this situation.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Saint Antoine, 184 rue du Faubourg Saint Antoine, F-75012 Paris, France. bruno.carbonne@sat.ap-hop-paris.fr
authors.forename: Bruno
authors.initials: B
authors.lastname: Carbonne
authors.forename: Corinne
authors.initials: C
authors.lastname: Cudeville
authors.forename: Françoise
authors.initials: F
authors.lastname: Maillard
authors.forename: François
authors.initials: F
authors.lastname: Goffinet
mesh_terms: D000653:Amniotic Fluid; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005333:Fetus; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007226:Infant Mortality; D007231:Infant, Newborn; D007743:Labor, Obstetric; D008470:Meconium; D008471:Meconium Aspiration Syndrome / Q000453:epidemiology; D010092:Oximetry; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D012372:ROC Curve; D012535:Scalp / Q000098:blood supply*
chemical_list: D010100:Oxygen