[Diagnostic and prognostic clinical immunological criteria for evaluating the course of the posttraumatic period in patients with open mandibular fractures].
A total of 136 patients with open mandibular fractures were examined, 53 of these at risk of inflammatory complications in the posttraumatic period. Analysis of the wound cytology, hematological changes, local and system immunity reactions suggest that phagocytosis dysfunction, imbalance of local immunity factors (primarily production, complex formation, and secretion of serum IgA) are significant factors in the development of posttraumatic immune deficiency. Statistical analysis showed clear-cut correlation between local immunity parameters (serum IgA, salivary IgG, levels of circulating immune complexes and medium-weight molecules in the saliva) and hematological values (leukocyte and lymphocyte counts, leukocytic intoxication index, and Rietes coefficient), which confirmed the reliability of prediction of inflammatory complications and necessity of immunocorrection in this patient population.
Novosiadlaia
N V
NV
Belovolova
R A
RA
Novgorodskiĭ
S V
SV
Novgorodskiĭ
V E
VE
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood; D017102:Fracture Healing / Q000276:immunology*; D005597:Fractures, Open / Q000150:complications / Q000175:diagnosis* / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008337:Mandibular Fractures / Q000150:complications / Q000175:diagnosis* / Q000276:immunology*; D008875:Middle Aged; D011379:Prognosis; D015203:Reproducibility of Results; D012463:Saliva / Q000276:immunology
D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A; D007074:Immunoglobulin G