title: Radiographic analysis of pasteurized autologous bone graft.
abstract: OBJECTIVE
  Local malignant bone tumor excision followed by pasteurization and subsequent reimplantation is a unique technique for reconstruction after resection of primary bone sarcomas. The purpose of this investigation was to assess the normal and abnormal long-term radiographic findings of intercalary and osteo-chondral pasteurized bone graft/implant composite.
  
  
  METHODS
  The long-term radiographic findings of pasteurized bone grafts used in reconstruction after resection of bone and soft tissue sarcomas in relation to patients' clinical data were reviewed retrospectively. Thirty-one patients (18 females, 13 males; age range 7-77 years, mean 30 years) who underwent surgery between April 1990 and January 1997 at the authors' institute constituted the material of this study. They were followed up for at least 3 years or until the patient's death (mean 69 months). The International Society of Limb Salvage graft evaluation method that assesses the fusion, resorption, fracture, graft shortening, fixation, subluxation, joint narrowing and subchondral bone was used for evaluation of the radiographs.
  
  
  CONCLUSIONS
  Twenty-one patients (68%) showed complete incorporation of graft and eight patients (26%) had partial incorporation. The overall radiographic evaluation rate was 81%. Fracture (10%) and infection (16%) were the main complications. No local recurrence was detected. These results indicate that pasteurization of bone is a useful option for reconstruction after resection of malignant bone tumors.
authors.affiliation: Department of Orthopedic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Kamiikebukuro 1-37-1, Toshima-ku, 170-0012 Tokyo, Japan.
authors.forename: Adel Refaat
authors.initials: AR
authors.lastname: Ahmed
authors.forename: Jun
authors.initials: J
authors.lastname: Manabe
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Kawaguchi
authors.forename: Seiichi
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Matsushita
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation / Q000000981:diagnostic imaging / Q000379:methods; D005121:Extremities; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D013242:Sterilization; D013997:Time Factors; D014182:Transplantation, Autologous; D016896:Treatment Outcome