title: A practical and convenient synthesis of hotrienol, an excellent fruity smelling compound.
abstract: The practical and convenient synthesis of hotrienol, which is an excellent fruity smelling compound, has been performed by the ene-type chlorination of linalyl acetate and then dehydrochlorinated by lithium bromide and lithium carbonate in DMF, followed by hydrolysis in three steps with an overall yield of 55%.
authors.affiliation: Technical Engineering Department, Fine Chemical Division, Takasago International Corporation, 1-5-1 Nishiyawata, Hiratsuka, Kanagawa, 254-0073, Japan. yoshifumi_yuasa@takasago.com
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Yuasa
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kato
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis*; D001965:Bromides / Q000737:chemistry; D002713:Chlorine / Q000737:chemistry; D005638:Fruit; D006868:Hydrolysis; D016651:Lithium Carbonate / Q000737:chemistry; D018020:Lithium Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes / Q000737:chemistry; D009812:Odorants
chemical_list: D000475:Alkenes; D001965:Bromides; D018020:Lithium Compounds; D039821:Monoterpenes; D016651:Lithium Carbonate; D002713:Chlorine; C074463:linalyl acetate; C040949:lithium bromide; C476493:3,7-dimethyl-1,5(E),7-octatrien-3-ol