title: Contraindications to vaccination in children. Mainly immunosuppression and a history of severe reactions.
abstract: (1) A history of severe anaphylactic reaction to a vaccine or one of its components is an absolute contraindication to the use of the same vaccine. (2) Live vaccines (viral or bacterial) are contraindicated in children with impaired immune response; this includes children receiving high-dose steroids. (3) BCG vaccination is contraindicated in HIV-seropositive children regardless of immune status. (4) Vaccination need not be postponed in children with common illnesses such as rhinopharyngitis; in children with a history of asthma or eczema; in children taking antibiotics; or in babies who are breast fed. (5) The contraindications of pertussis vaccination are now well defined (mainly neurological diseases). (6) Very few studies have assessed the adverse effects of vaccination on the outcome of pregnancy or on the unborn child. In practice, vaccination of pregnant women can usually wait until after delivery.
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced; D002648:Child; D000075202:Contraindications; D005260:Female; D006801:Humans; D007115:Immunization Schedule; D007153:Immunologic Deficiency Syndromes / Q000150:complications; D010567:Pertussis Vaccine / Q000009:adverse effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014611:Vaccination / Q000009:adverse effects*; D014765:Viral Vaccines / Q000009:adverse effects*
chemical_list: D010567:Pertussis Vaccine; D014765:Viral Vaccines