Analysis of genetic identity of North American Anaplasma phagocytophilum strains by pulsed-field gel electrophoresis.
Biological and geographic heterogeneity of anthropozoonosis caused by Anaplasma phagocytophilum is poorly understood. Seven North American A. phagocytophilum strains were compared by PFGE. The average genome size was 1.58 Mbp, and restriction patterns were identical. New World strains of A. phagocytophilum have a large genome and a high degree of genetic uniformity.
Dumler
J S
JS
Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. sdumler@jhmi.edu
Asanovich
K M
KM
Bakken
J S
JS
D041081:Anaplasma phagocytophilum / Q000145:classification* / Q000235:genetics*; D000818:Animals; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000032:analysis; D004285:Dogs; D016873:Ehrlichiosis / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D009656:North America; D015183:Restriction Mapping
D004269:DNA, Bacterial