Hemodynamic parameters by color Doppler ultrasound and dynamic enhanced magnetic resonance imaging in palpable T1 breast cancers.
Prospective study in 31 women with T1 breast cancers (24 invasive breast cancers and 7 in situ breast cancers) consisting of no vessel or a single vessel as demonstrated by color Doppler ultrasound (US), CDUS, who received dynamic enhanced magnetic resonance (eMRI). The flow parameters measured by CDUS and dynamic eMRI were statistically correlated and analyzed in distinguishing the invasive or in situ breast cancers and in predicting the axillary nodal status. All of the cancers were enhanced by dynamic eMRI; however, only 22 had color flow demonstrated by CDUS; 9 invasive cancers had metastasized to the lymph node. There was no correlation between the flow indices on CDUS and signal intensities on dynamic eMRI. Patterns of the signal-time curves of invasive and in situ cancers were statistically distinguishable and the correlation between lymph node status and peak systolic velocity was statistically significant. Hemodynamic parameters measured by CDUS and dynamic eMRI carry independent values in evaluating T1 breast cancers. With the knowledge of hemodynamic information, a more comprehensive approach to the treatment of these cancers can be achieved.
Cheung
Yun-Chung
YC
Department of Diagnostic Radiology, College of Medicine and School of Mecial Technology, Chang Gung University, Kwei Shan, Tao Yuan Hsien, Taiwan. alex2143@ms33.hinet.net
Lo
Yung-Feng
YF
See
Lai-Chu
LC
Chen
Shin-Cheh
SC
Chao
Tzu-Chieh
TC
D000328:Adult; D001783:Blood Flow Velocity; D001943:Breast Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011379:Prognosis; D011446:Prospective Studies; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D016217:Ultrasonography, Mammary / Q000379:methods