Autologous hematopoietic stem cell transplantation for Crohn's disease.
The feasibility and early experience of hematopoietic stem cell transplantation for severe Crohn's disease (CD) are discussed. The natural history, therapy, and evidence for autoimmunity of CD are outlined and related to this new therapy in terms of morbidity and mortality.
Craig
Robert M
RM
Northwestern University Medical School, 233 E. Erie, Suite 206, Chicago, IL 60611, USA. r-craig@northwestern.edu
D000818:Animals; D015551:Autoimmunity; D003424:Crohn Disease / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D014182:Transplantation, Autologous