title: [Death risk factors of severe acute respiratory syndrome with acute respiratory distress syndrome].
abstract: OBJECTIVE
  To discuss the possible death risk factors of severe acute respiratory syndrome (SARS) with acute respiratory distress syndrome (ARDS).
  
  
  METHODS
  Twenty-five patients suffered from SARS with ARDS in the intensive care unit were retrospectively analyzed from December 2002 to April 2003. Statistical analysis was made using SPSS 10.0 and forward stepwise (wald) logistic regression analysis were used to determine the interrelationships between multiple variables and death. P<0.05 was considered statistically significant.
  
  
  RESULTS
  The following factors were associated with a significantly higher mortality rate in the SARS with ARDS patients, including age increase (OR=1.203, CI=1.036 to 1.396, P=0.016), long-time hypoxia(OR=1.067, CI=1.014 to 1.122, P=0.013), thrombocytopenia(OR=111.932, CI=6.096 to 2 055.252, P=0.001), hypernatremia (OR=26.667, CI=2.242 to 317.147, P=0.009), and elevation of serum creatinine levels (OR=111.932, CI=6.096 to 2 055.252, P=0.001).
  
  
  CONCLUSIONS
  More attention should be paid to deal with these risk factors and to prevent the development of serious complications associated with SARS.
authors.affiliation: Guangzhou Institute of Respiratory Disease, Yingdong Critical Care Medical Center, Guangzhou 510120, Guangdong, China.
authors.forename: Wei-qun
authors.initials: WQ
authors.lastname: He
authors.forename: Si-bei
authors.initials: SB
authors.lastname: Chen
authors.forename: Xiao-qing
authors.initials: XQ
authors.lastname: Liu
authors.forename: Yi-min
authors.initials: YM
authors.lastname: Li
authors.forename: Zheng-lun
authors.initials: ZL
authors.lastname: Xiao
authors.forename: Nan-shan
authors.initials: NS
authors.lastname: Zhong
mesh_terms: D000328:Adult; D000367:Age Factors; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D006955:Hypernatremia / Q000150:complications; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications*; D012189:Retrospective Studies; D012307:Risk Factors; D045169:Severe Acute Respiratory Syndrome / Q000150:complications / Q000401:mortality*; D015996:Survival Rate; D013921:Thrombocytopenia / Q000150:complications
chemical_list: D003404:Creatinine