Yersinia pestis TonB: role in iron, heme, and hemoprotein utilization.
In Yersinia pestis, the siderophore-dependent yersiniabactin (Ybt) iron transport system and heme transport system (Hmu) have putative TonB-dependent outer membrane receptors. Here we demonstrate that hemin uptake and iron utilization from Ybt are TonB dependent. However, the Yfe iron and manganese transport system does not require TonB.
Perry
Robert D
RD
Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, Kentucky 40536-8994, USA. rperry@pop.uky.edu
Shah
Jessica
J
Bearden
Scott W
SW
Thompson
Jan M
JM
Fetherston
Jacqueline D
JD
D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D029968:Escherichia coli Proteins / Q000235:genetics; D006418:Heme / Q000378:metabolism*; D006420:Hemeproteins / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D021381:Protein Transport
D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; C052874:ExbB protein, E coli; C447836:HasB protein, Serratia marcescens; D006420:Hemeproteins; D008565:Membrane Proteins; C057616:tonB protein, Bacteria; C489181:tonB protein, E coli; C060790:exbD protein, E coli; D006418:Heme; D007501:Iron