title: Wound-healing trajectories.
abstract: Healing of a wound is a dynamic process involving soluble mediators, a variety of cells, and extracellular matrix. These components are involved in a number of different processes or steps in healing, including coagulation, inflammation, fibroplasia, collagen deposition, epithelialization, and scar contraction with remodeling. The processes can be organized into three phases: inflammation, fibroplasia, and remodeling. The events in healing occur in an orderly and timely fashion, and there is significant overlap between each of the processes.
authors.affiliation: Wound Healing/Limb Preservation Clinic, A1011 Presbyterian, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA. steeddl@msx.upmc.edu
authors.forename: David L
authors.initials: DL
authors.lastname: Steed
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D006801:Humans; D011183:Postoperative Complications; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*; D014950:Wounds, Penetrating / Q000503:physiopathology* / Q000628:therapy*