[Effect of noninvasive positive pressure ventilation on treatment of acute respiratory distress syndrome].
OBJECTIVE
To investigate the factors affecting the effect of noninvasive positive pressure ventilation (NIPPV) on treatment of acute respiratory distress syndrome (ARDS).


METHODS
According to the disease-induced factors, patients with ARDS were divided into two groups: group A (pulmonary factors), group B (extra-pulmonary factors). Different kinds of ventilator s were used in the course of NIPPV via facial or nasal mask. The mode, biphasic intermittent positive airway pressure (BiPAP, BiPAP vision), pressure support ventilation (PSV) + positive end-expiratory pressure (PEEP) or synchronized intermittent mandatory ventilation (SIMV) + PSV + PEEP, was administered. After 3-10 hours, the patients who were not fit to NIPPV were conducted intubation.


RESULTS
Group A had 9 cases, of whom 5 cases were treated with NIPPV all the time, while in group B, 14 cases, of whom 12 cases The cure rate of group A by NIPPV was 55.6% (5/9), while that of group B was 85.7% (12/14), P<0.05.


CONCLUSIONS
Selecting proper indication, reasonable ventilator mode and parameters, and improving the unfavorable factors can contribute to the decrease of intubation rate.
Xu
Si-cheng
SC
Respiratory Department, First Affiliated Hospital of Xinjiang Medical University, Urmqi 830000, Xinjiang, China.
Huang
Yi-fen
YF
Wang
Xi-yan
XY
Jia
Min
M
D000328:Adult; D000368:Aged; D001784:Blood Gas Analysis; D005260:Female; D006801:Humans; D008297:Male; D008397:Masks; D008875:Middle Aged; D011175:Positive-Pressure Respiration / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000097:blood / Q000628:therapy*; D016896:Treatment Outcome