title: [Hypogammaglobulinemia associated with thymoma (Good syndrome) similar to diffuse panbronchiolitis].
abstract: A 65-year-old woman complained of dyspnea and a productive cough after surgical treatment and irradiation therapy for thymoma. Chest radiography and high-resolution computed tomography showed small nodules in centrilobular lesions in all of both lung fields, but predominantly in the lower fields. In addition, blood tests showed hypogammaglobulinemia. Chronic sinusitis, mild hypoxemia, severe obstructive impairment and the pathological findings of bronchiolitis led to a diagnosis of sinobronchial syndrome caused by Good syndrome. Treatment with oral erythromycin 600 mg/day was started. After 6 months, the patient improved both clinically and radiologically. Low-dose, long-term treatment with erythromycin was effective against sinobronchial syndrome caused by Good syndrome.
authors.affiliation: First Department of Internal Medicine, Yokohama City University School of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuburai
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Ikehara
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Suzuki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shinohara
authors.forename: Wataru
authors.initials: W
authors.lastname: Mishima
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tagawa
authors.forename: Masaru
authors.initials: M
authors.lastname: Itou
authors.forename: Naoki
authors.initials: N
authors.lastname: Miyazawa
authors.forename: Harumi
authors.initials: H
authors.lastname: Nishiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Shoji
authors.forename: Motoyoshi
authors.initials: M
authors.lastname: Suzuki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Matsuse
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ishigatsubo
mesh_terms: D000361:Agammaglobulinemia / Q000150:complications*; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001988:Bronchiolitis / Q000188:drug therapy* / Q000209:etiology; D004917:Erythromycin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy; D013577:Syndrome; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin