[Expression of gamma-aminobutyric acid receptor gamma 1 subunit in the end-organs of rat vestibule].
OBJECTIVE
To investigate the expression of the gamma-aminobutyric acid receptor gamma 1 subunit in the end-organs of rat vestibule.


METHODS
Using a combination of reverse transcription followed by polymerase chain reaction, expression of the gamma-aminobutyric acid receptor gamma 1 subunit in the end-organs of rat vestibule was examined. The rat brain RNA was used as positive control.


RESULTS
PCR amplification products representing subunit gene expression for gamma-aminobutyric acid receptor alpha 1 subunit were amplified.


CONCLUSIONS
The results showed that gamma-aminobutyric acid receptor gamma 1 subunit was expressed in the rat vestibule, indicating that GABA is one of the important neurotransmitters in the vestibular system.
Cheng
Huamao
H
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
Kong
Weijia
W
D000818:Animals; D002478:Cells, Cultured; D015870:Gene Expression / Q000235:genetics; D051381:Rats; D018079:Receptors, GABA / Q000096:biosynthesis* / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014722:Vestibule, Labyrinth / Q000378:metabolism*
D018079:Receptors, GABA