C-H activation/borylation/oxidation: a one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups.
An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses.
Maleczka
Robert E
RE
Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA. maleczka@cem.msu.edu
Shi
Feng
F
Holmes
Daniel
D
Smith
Milton R
MR
D001880:Boranes / Q000737:chemistry*; D010084:Oxidation-Reduction; D010636:Phenols / Q000138:chemical synthesis*
D001880:Boranes; D010636:Phenols