title: Factors associated with oropharyngeal human immunodeficiency virus shedding.
abstract: Orogenital transmission of human immunodeficiency virus (HIV) is considered to be inefficient, and infectious HIV is rarely detected in saliva. To evaluate the posterior oropharynx as a source of HIV shedding, we studied 64 HIV-infected men who have sex with men in Seattle, Washington, and Lima, Peru. In multivariate analysis, receipt of antiretroviral therapy, higher CD4 cell count, and history of tonsillectomy were predictors of lower pharyngeal HIV RNA levels.
authors.affiliation: Department of Medicine, University of Washington, Seattle, Washington 98104, USA. zuckermn@u.washington.edu
authors.forename: Richard A
authors.initials: RA
authors.lastname: Zuckerman
authors.forename: William L H
authors.initials: WL
authors.lastname: Whittington
authors.forename: Connie L
authors.initials: CL
authors.lastname: Celum
authors.forename: Tarquin
authors.initials: T
authors.lastname: Collis
authors.forename: Aldo
authors.initials: A
authors.lastname: Lucchetti
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Sanchez
authors.forename: James P
authors.initials: JP
authors.lastname: Hughes
authors.forename: Jose L
authors.initials: JL
authors.lastname: Sanchez
authors.forename: Robert W
authors.initials: RW
authors.lastname: Coombs
mesh_terms: D000328:Adult; D015658:HIV Infections / Q000635:transmission; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009960:Oropharynx / Q000821:virology*; D012367:RNA, Viral / Q000032:analysis; D017201:Virus Shedding
chemical_list: D012367:RNA, Viral