title: Screening of Mongolian plants for influence on amylase activity in mouse plasma and gastrointestinal tube.
abstract: Mongolian plants were screened for their influence on alpha-amylase activity in mouse plasma. Methanolic extracts of Geranium pratense, Rhodiola rosea, Ribes pullchelum and Vaccinium uliginosum inhibited the enzyme activity in isolated mouse plasma by greater than 40% and the effect was concentration dependent. Vaccinium uliginosum also showed a depressive effect on elevation of postprandial blood glucose to some extent.
authors.affiliation: Tohoku Pharmaceutical University, Sendai, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Eriko
authors.initials: E
authors.lastname: Baba
authors.forename: Shinji
authors.initials: S
authors.lastname: Fushiya
authors.forename: Fumihide
authors.initials: F
authors.lastname: Takano
authors.forename: Javzan
authors.initials: J
authors.lastname: Batkhuu
authors.forename: Tzezengiin
authors.initials: T
authors.lastname: Dash
authors.forename: Chinbat
authors.initials: C
authors.lastname: Sanchir
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Yoshizaki
mesh_terms: D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods; D041981:Gastrointestinal Tract / Q000187:drug effects* / Q000201:enzymology*; D008297:Male; D051379:Mice; D008986:Mongolia; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D028321:Plant Preparations / Q000302:isolation & purification / Q000494:pharmacology*; D018514:Plant Structures; D000516:alpha-Amylases / Q000037:antagonists & inhibitors* / Q000097:blood*
chemical_list: D010936:Plant Extracts; D028321:Plant Preparations; D000516:alpha-Amylases