title: [An autopsy case of purulent meningitis, presenting high signals in subarachnoid space and ventricles in diffusion weighted images (DWIs)].
abstract: A 79-year-old, bedridden woman with an untreated colon cancer, developed abrupt disturbance of consciousness and high fever. Brain MRI showed significant high signals in the subarachnoid space and ventricles in diffusion-weighted images (DWIs), and she died on the same day. At autopsy, much exudate was found over the base of the brain, leading to a diagnosis of purulent meningitis. On histological findings, inflammatory cell infiltration was significantly restricted within the subarachnoid space, but not into the brain parenchyma. This case report demonstrated that high signals in subarachnoid space and ventricles in DWIs may be very useful for diagnosis of purulent meningitis.
authors.affiliation: Department of Neurology, Tosei General Hospital.
authors.forename: Takuya
authors.initials: T
authors.lastname: Oguri
authors.forename: Shigehisa
authors.initials: S
authors.lastname: Mitake
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yuasa
authors.forename: Takanari
authors.initials: T
authors.lastname: Toyoda
authors.forename: Norihiko
authors.initials: N
authors.lastname: Uematsu
authors.forename: Toshiyasu
authors.initials: T
authors.lastname: Miura
authors.forename: Mari
authors.initials: M
authors.lastname: Yoshida
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Hashizume
authors.forename: Koji
authors.initials: K
authors.lastname: Takada
authors.forename: Kosei
authors.initials: K
authors.lastname: Ojika
mesh_terms: D000368:Aged; D002552:Cerebral Ventricles / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000473:pathology*; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D016920:Meningitis, Bacterial / Q000175:diagnosis / Q000473:pathology*; D013346:Subarachnoid Space / Q000473:pathology*