title: Tools for discovery: gene expression enterprise solutions.
abstract: Expression profiling in drug discovery is a highly collaborative process requiring robust, centralized databases and exhaustive exploration of expanding libraries of expression experiments. In this review, state-of-the-art data analysis tools that identify relationships between gene expression and biological activities are described. Informatics workflow, system scalability and regulatory compliance issues are discussed in the context of expression data management.
authors.affiliation: Silicon Genetics, 2601 Spring Street, Redwood City, CA 94063, USA. anoop@silicongenetics.com
authors.forename: Anoop
authors.initials: A
authors.lastname: Grewal
authors.forename: Jordan
authors.initials: J
authors.lastname: Stockton
authors.forename: Catherine
authors.initials: C
authors.lastname: Bolger
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D006801:Humans; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000379:methods* / Q000639:trends