title: Stereotactic radiosurgery. XVII: Recurrent intrasellar craniopharyngioma.
abstract: Stereotactic radiosurgery for craniopharyngioma is usually a high risk procedure due to the intimate relationship of the tumour to the optic chiasm and conservative dosing has been advocated to reduce complication rates. In 2002, in a publication from Karolinska Hospital, Sweden, 13 out of 21 patients received only a marginal dose of 6 Gy (not considered a radical dose) and 11 out of 13 tumours progressed. This recent report must argue against single dose stereotactic radiosurgery as the primary radiation therapy modality in most cases. However, where the disease is 'away' from the optic apparatus, such constraints do not apply. We here report the successful treatment of three consecutive patients whose craniopharyngioma was confined to the pituitary fossa, and a finite distance from the optic pathways and in whom optimal dosing was employed.
authors.affiliation: Department of Radiotherapy, St Bartholomew's Hospital, London Radiosurgical Centre, London, UK.
authors.forename: A S N
authors.initials: AS
authors.lastname: Jackson
authors.forename: E J
authors.initials: EJ
authors.lastname: St George
authors.forename: R J
authors.initials: RJ
authors.lastname: Hayward
authors.forename: P N
authors.initials: PN
authors.lastname: Plowman
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery*; D016634:Radiosurgery / Q000379:methods*; D016896:Treatment Outcome