title: Easy approach to chiral Michael adducts by Eu+3-catalyzed conjugate addition.
abstract: Michael addition of enantiopure N-acetoacetyl-oxazolidin-2-ones is shown to take place in the presence of catalytic amounts of Eu(+3) salts and complexes in high yields, very reduced reaction times, and moderate diastereoselectivity. The level of diastereoselectivity can be significantly enhanced by the suitable exploitation of the easy epimerization of the adducts in the presence of silica gel.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Salerno, Baronissi (SA), Italy.
authors.forename: Margherita
authors.initials: M
authors.lastname: De Rosa
authors.forename: Laura
authors.initials: L
authors.lastname: Palombi
authors.forename: Maria Rosaria
authors.initials: MR
authors.lastname: Acocella
authors.forename: Marina
authors.initials: M
authors.lastname: Fruilo
authors.forename: Rosaria
authors.initials: R
authors.lastname: Villano
authors.forename: Annunziata
authors.initials: A
authors.lastname: Soriente
authors.forename: Arrigo
authors.initials: A
authors.lastname: Scettri