A simple and highly practical oxidation of primary alcohols to acids mediated by 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO).
Primary alcohols were quantitatively oxidized in one-pot to acids via 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) mediated oxidation. The reported method is simple and suitable for large scale synthesis.
Zanka
Atsuhiko
A
Chemical Development Laboratories, Fujisawa Pharmaceutical Co. Ltd, Osaka, Japan.
D000143:Acids / Q000378:metabolism*; D000438:Alcohols / Q000378:metabolism*; D002384:Catalysis / Q000187:drug effects; D003497:Cyclic N-Oxides / Q000378:metabolism* / Q000494:pharmacology; D010084:Oxidation-Reduction / Q000187:drug effects; D013113:Spin Labels; D013678:Technology, Pharmaceutical / Q000379:methods*
D000143:Acids; D000438:Alcohols; D003497:Cyclic N-Oxides; D013113:Spin Labels; C003959:TEMPO