The effect of C. burnetii infection on the quality of life of patients following an outbreak of Q fever.
Sixty-six cases of Q fever were diagnosed in people affiliated with a goat-farming co-operative in rural Newfoundland in the spring of 1999. Follow-up studies which included administration of the Short Form 36 Health Survey (SF-36) were conducted 3 and 27 months after the initial outbreak to prospectively follow the effects of acute Q fever on the quality of life of the participants. Twenty-seven months after the outbreak 51% of those who had Q fever reported persistent symptoms including seven participants whose symptoms had initially resolved 3 months after the outbreak. Individuals with Q fever had significantly lower scores on five of the eight scales in the SF-36 and lower scores in the mental and physical summary scales compared to uninfected controls. Although this supports the hypothesis of a 'post Q fever fatigue syndrome' (QFFS), further study is warranted.
Hatchette
T F
TF
Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada.
Hayes
M
M
Merry
H
H
Schlech
W F
WF
Marrie
T J
TJ
D016022:Case-Control Studies; D004196:Disease Outbreaks; D015673:Fatigue Syndrome, Chronic / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D009523:Newfoundland and Labrador / Q000453:epidemiology; D011778:Q Fever / Q000150:complications* / Q000453:epidemiology; D011788:Quality of Life