Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?
Litvinov
Ivan V
IV
The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
De Marzo
Angelo M
AM
Isaacs
John T
JT
D002454:Cell Differentiation / Q000502:physiology; D015195:Drug Design; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology*; D011944:Receptors, Androgen / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
D011944:Receptors, Androgen