title: A novel one-pot method for the preparation of pyrazoles by 1,3-dipolar cycloadditions of diazo compounds generated in situ.
abstract: A convenient one-pot procedure for the preparation of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds generated in situ has been developed. Diazo compounds derived from aldehydes were reacted with terminal alkynes to furnish regioselectively 3,5-disubstituted pyrazoles. Furthermore, the reaction of N-vinylimidazole and diazo compounds derived from aldehydes gave exclusively 3-substituted pyrazoles in a one-pot process.
authors.affiliation: School of Chemistry, Bristol University, Cantock's Close, Bristol BS8 1TS, UK. v.aggarwal@bristol.ac.uk
authors.forename: Varinder K
authors.initials: VK
authors.lastname: Aggarwal
authors.forename: Javier
authors.initials: J
authors.lastname: de Vicente
authors.forename: Roger V
authors.initials: RV
authors.lastname: Bonnert