title: Synthesis of indoles via palladium[0]-mediated Ullmann cross-coupling of o-halonitroarenes with alpha-halo-enones or -enals.
abstract: [reaction: see text] Palladium[0]-mediated Ullmann cross-coupling of o-halonitrobenzene (1) and various related nitroarenes with a range of alpha-halo-enones (e.g., 2) or -enals readily affords the expected alpha-arylenones, e.g., 3, or -enals, which are converted into the corresponding indoles, e.g., 4, on reaction with dihydrogen in the presence of Pd on C.
authors.affiliation: Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia. mgb@rsc.anu.edu.au
authors.forename: Martin G
authors.initials: MG
authors.lastname: Banwell
authors.forename: Brian D
authors.initials: BD
authors.lastname: Kelly
authors.forename: Okanya J
authors.initials: OJ
authors.lastname: Kokas
authors.forename: David W
authors.initials: DW
authors.lastname: Lupton