title: Preliminary results with the use of AlloDerm in chronic otitis media.
abstract: OBJECTIVE
  AlloDerm, an acellular dermal graft, has been used successfully as a material for soft tissue implantation. The authors report their experience with the use of AlloDerm in the reconstruction of the tympanic membrane.
  
  
  METHODS
  Case review study.
  
  
  METHODS
  Charts were reviewed for all patients who underwent tympanoplasty with and without mastoidectomy between June 1999 and June 2002 in whom AlloDerm was used as a grafting material. There were 24 patients, 17 with simple perforations (8 revisions) and 7 with chronic otitis media with cholesteatoma (6 revisions). Success was defined as closure of the tympanic membrane perforation.
  
  
  RESULTS
  Closure of the perforation using AlloDerm was achieved in 87.5% of the patients (ie, in all but three patients). Another patient developed serous otitis media and required a myringotomy tube in the postoperative period.
  
  
  CONCLUSIONS
  The success rate for AlloDerm in tympanoplasty was similar to that of temporalis fascia in the authors' experience. AlloDerm can provide a suitable grafting material when fascia is not available or when the size of the defect precludes the use of fascia.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, Columbia University College of Physicians and Surgeons, The New York-Presbyterian Hospital, 180 Fort Washington Avenue, Harkness Pavilion, Suite 813, New York, NY 10032, USA. jfayed@aol.com
authors.forename: Jose N
authors.initials: JN
authors.lastname: Fayad
authors.forename: Tony
authors.initials: T
authors.lastname: Baino
authors.forename: Simon C
authors.initials: SC
authors.lastname: Parisier
mesh_terms: D001672:Biocompatible Materials; D018424:Cholesteatoma, Middle Ear / Q000150:complications / Q000601:surgery*; D002908:Chronic Disease; D003094:Collagen; D006801:Humans; D008416:Mastoid / Q000601:surgery; D009225:Myringoplasty / Q000379:methods; D010033:Otitis Media / Q000150:complications*; D011183:Postoperative Complications; D017768:Skin, Artificial; D018058:Tympanic Membrane Perforation / Q000150:complications / Q000601:surgery*
chemical_list: C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen