Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy.
METHODS
We present the case of a 25-year-old woman with treatment resistant hyperemesis gravidarum in the 15th week with a 13 kg loss of body weight. When the patient asked for termination of the pregnancy because of the unbearable symptoms, treatment with intravenous mirtazapine (Remergil) was started.


RESULTS
Nausea and vomiting disappeared within hours, pregnancy termination was no longer desired. The patient was discharged two weeks later in good health and at 36 weeks gestation a cesarean section was performed. Post partum evaluation as well as 6-month post-partum revealed no dysmorphology or laboratory abnormalities in the children.
Rohde
Anke
A
Department of Psychosomatics in Gynecology, Women's University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. anke.rohde@ukb.uni-bonn.de
Dembinski
Joerg
J
Dorn
Christoph
C
D000028:Abortion, Induced / Q000523:psychology*; D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000188:drug therapy*; D007262:Infusions, Intravenous; D008803:Mianserin / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D000078785:Mirtazapine; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D014427:Twins
D000929:Antidepressive Agents, Tricyclic; D008803:Mianserin; D000078785:Mirtazapine