Placental site trophoblastic tumor.
Placental site trophoblastic tumor (PSTT) is an uncommon form of gestational trophoblastic disease (GTD) with variable spectrum of clinical behavior. PSTT can occur after a normal pregnancy, spontaneous abortion, termination of pregnancy, ectopic pregnancy or molar pregnancy. Surgery is the primary treatment. Chemotherapy has an established role in loco-regionally advanced and metastatic disease. Many studies indicate that mitotic index is an important prognostic indicator. This article reviews the literature on this rare disease.
Ajithkumar
T V
TV
Oncology Centre, Addenbrooke's NHS Trust, Box 193, Hills Road, Cambridge CB2 2QQ, United Kingdom. tvajith@hotmail.com
Abraham
Elizabeth K
EK
Rejnishkumar
R
R
Minimole
A L
AL
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009362:Neoplasm Metastasis; D010922:Placenta Diseases / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D011379:Prognosis; D012307:Risk Factors; D014328:Trophoblastic Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery