title: Guttate morphoea in human T-cell lymphoma/lymphotrophic virus type-1 (HTLV-1) infection.
abstract: A 62-year-old Japanese man presented with multiple small atrophic macules on the trunk and extremities. The lesions were discrete, oval in shape and enclosed by lilac ring. They were distributed in a Christmas tree distribution, reminiscent of pityriasis rosea. Skin biopsy showed increased collagen fibres in the dermis and invading subcutaneous tissue. The clinico-pathological features were consistent with guttate morphoea, a rare variant of localized scleroderma. Serological tests revealed a positive reaction to human T-cell lymphoma/lymphotropic virus type-1 infection.
authors.affiliation: Department of Dermatology, Osaka City University Graduate School of Medicine, Abeno, Osaka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Oiso
authors.forename: K
authors.initials: K
authors.lastname: Fukai
authors.forename: N
authors.initials: N
authors.lastname: Hosomi
authors.forename: M
authors.initials: M
authors.lastname: Ishii
mesh_terms: D001706:Biopsy; D024042:Collagen Type I / Q000378:metabolism; D015368:Human T-lymphotropic virus 1; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000473:pathology / Q000821:virology*; D012698:Serologic Tests; D017193:Skin Diseases, Viral / Q000150:complications*; D016212:Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1
chemical_list: D024042:Collagen Type I; C508960:TGFB1 protein, human; D016212:Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1