title: [Acute thrombosis of lower extremities. Risk factors, methods of prevention and treatment].
abstract: The results of treatment of 526 patients with an acute venous thrombosis of the lower extremities aged from 23 to 70 years, including 140 (36.3%) men and 376 (63.7%) women, were analyzed. The main etiological factors of thrombosis were physical overload, operations with subsequent immobilization, trauma of lower extremities, pregnancy and delivery, tumor of small pelvis and of other localization. In 65 patients an acute venous thrombosis was complicated by thromboembolism of pulmonary artery (TEPA), 2 patients died before initiation of treatment. Conduction of conservative therapy in 314 (94.4%) patients with thrombosis of the lower extremities deep veins using fraxiparine (fraxiparine forte) have allowed to achieve considerable improvement of their state. In 80 patients with thrombosis of subcutaneous veins was performed ligature of mouth for prophylaxis of TEPA, in all of them good clinical result was noted. High efficacy of fraxiparine application in prophylactical dosage for prevention of the venous thromboembolism occurrence was noted.
authors.forename: A B
authors.initials: AB
authors.lastname: Gubka
authors.forename: V I
authors.initials: VI
authors.lastname: Pertsov
authors.forename: V A
authors.initials: VA
authors.lastname: Gubka
authors.forename: L P
authors.initials: LP
authors.lastname: Karnaukh
authors.forename: D A
authors.initials: DA
authors.lastname: Buga
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020246:Venous Thrombosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control
chemical_list: D005343:Fibrinolytic Agents