[Inhaled corticosteroids in idiopathic pulmonary hemosiderosis: 2 cases].
Idiopathic pulmonary hemosiderosis, a rare clinical entity, is characterized by bleeding into the alveoli and progressive pulmonary fibrosis. It is usually treated with systemic corticosteriod during acute bleeding episodes and with prolonged courses of oral corticosteroids and/or other immunosuppressant drugs for maintenance therapy. Because prolonged treatment with these agents is frequently associated with significant side effects, favorable response to inhaled corticosteroids would be ideal in this condition. The authors reports 2 cases of idiopathic pulmonary hemosiderosis diagnoses in the pediatric department of Sfax: a 20 month old boy and an 8 year old girl successfully treated with inhaled beclomethazone dipropionate using doses of 500_g/day and low dose oral prednisolone (0.5 mg/kg one day/2).
Ben Halima
Nabil
N
Service de pédiatrie CHU Hédi Chaker, Sfax.
Karray
Abderrahmen
A
Krichen
Anas
A
Feki
Hichem
H
Ben Salah
Mounir
M
Chabchoub
Imène
I
Hachicha
Mongia
M
Mahfoudh
Abdelmajid
A
Triki
Ali
A
D000280:Administration, Inhalation; D001507:Beclomethasone / Q000008:administration & dosage*; D002648:Child; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006486:Hemosiderosis / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage*; D016896:Treatment Outcome
D005938:Glucocorticoids; D011239:Prednisolone; D001507:Beclomethasone