title: Human immunodeficiency virus type 1 recombinant B/G subtypes circulating in Coimbra, Portugal.
abstract: An increasing prevalence of HIV-1 non-B variants is being noticed in several European regions, particularly in countries such as Portugal, which have closer contacts with African endemic areas, where multiple HIV subtypes cocirculate. HIV-1 subtyping by phylogenetic analyses of reverse transcriptase, protease and env (C2-V3) genomic regions was carried out in plasma collected from 18 HIV-1-infected subjects living in Coimbra, Portugal, and suspected to be infected with non-B variants. Three (16.7%) subjects carried recombinant B/G viruses (BV3/BRT/Gpro; GV3/URT/Bpro; AV3/GRT/Bpro), whereas all the remaining individuals were infected with HIV-1 subtype B. This is the first report of recombinant B/G subtypes in Portugal.
authors.affiliation: Department of Infectious Diseases, Hospitais da Universidade de Coimbra, Coimbra, Portugal.
authors.forename: V
authors.initials: V
authors.lastname: Duque
authors.forename: A
authors.initials: A
authors.lastname: Holguín
authors.forename: M
authors.initials: M
authors.lastname: Silvestre
authors.forename: J
authors.initials: J
authors.lastname: González-Lahoz
authors.forename: V
authors.initials: V
authors.lastname: Soriano
mesh_terms: D000328:Adult; D000349:Africa / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D011174:Portugal / Q000453:epidemiology; D011995:Recombination, Genetic