[Effects of 21 d -6 degrees head down bed-rest on pulmonary gas distribution and little airway function].
OBJECTIVE
To probe the effect of 21 d -6 degrees head down bed-rest (HDBR) on pulmonary gas distribution and little airway function.


METHODS
The indices of the pulmonary gas distribution and little airway function (delta N2, CV, CV/VC%, LCI) were measured in 16 healthy male subjects before, during and after 21 d -6 degrees HD-BR.


RESULTS
Comparing with before and early days of HDBR, recovery supine delta N2 increased significantly. CV increased significantly only on the first day of HDBR, and changes of CV/VC% were same as CV. The changes of LCI were not significant.


CONCLUSIONS
The indices of pulmonary gas distribution were affected by 21 d -6 degrees HDBR. Pulmonary gas distribution was more uneven during and after 21 d -6 degrees HDBR.
Wei
Shi-qiang
SQ
The 371 of PLA Hospital, Xinxiang, China.
Su
Shuang-ning
SN
Lu
Li-Li
LL
Li
Yong-zhi
YZ
Zhong
Chong-fa
CF
Ren
Hong-ru
HR
D000293:Adolescent; D000328:Adult; D001510:Bed Rest; D018475:Head-Down Tilt; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000502:physiology*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012123:Pulmonary Ventilation / Q000502:physiology*; D012129:Respiratory Function Tests; D012143:Respiratory Physiological Phenomena; D016683:Supine Position; D018474:Weightlessness Simulation
D009584:Nitrogen