Multiple sequence alignment with the Clustal series of programs.
The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the robustness, portability and user-friendliness of the programs. New features include NEXUS and FASTA format output, printing range numbers and faster tree calculation. Although, Clustal was originally developed to run on a local computer, numerous Web servers have been set up, notably at the EBI (European Bioinformatics Institute) (http://www.ebi.ac.uk/clustalw/).
Chenna
Ramu
R
European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.
Sugawara
Hideaki
H
Koike
Tadashi
T
Lopez
Rodrigo
R
Gibson
Toby J
TJ
Higgins
Desmond G
DG
Thompson
Julie D
JD
D000465:Algorithms; D000595:Amino Acid Sequence; D020407:Internet; D009696:Nucleic Acids / Q000737:chemistry; D010802:Phylogeny; D016415:Sequence Alignment / Q000379:methods*; D017421:Sequence Analysis; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
D009696:Nucleic Acids