The physiology of erectile dysfunction.
Male erectile dysfunction is a common urologic disorder which can have a profound detrimental impact on a patient's quality of life. Normal erectile function represents a complex physiologic process requiring integrated synchronized function of vascular, neurologic, and musculoskeletal body systems, with significant psychologic factors playing a role as well. A breakdown in any one of these body systems can contribute to the development of erectile dysfunction. As men age, many of the same risk factors for the development of cardiovascular disease also can have a detrimental effect on the organ systems needed for good erectile function. A solid grasp of the anatomy and physiology involved in normal erectile function is important in understanding the interactions between cardiovascular disease and erectile dysfunction, and in developing new ways to effectively treat and prevent both disease processes in the future.
Russell
Shane
S
Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Nehra
Ajay
A
D002318:Cardiovascular Diseases / Q000150:complications / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010410:Penile Erection / Q000502:physiology; D010413:Penis / Q000098:blood supply; D012307:Risk Factors