title: Metastatic choriocarcinoma in a middle-aged man presenting as a right thigh mass with venous thrombosis: a case report.
abstract: Choriocarcinoma is a highly aggressive beta-subunit of human chorionic gonadotropin (betaHCG)-producing germ cell tumor. In men, it is a rare neoplasm and can arise in the testes or in various extragonadal locations such as the retroperitoneum, mediastinum, and pineal body. We present a highly unusual case of a middle-aged man with primary metastatic betaHCG-producing choriocarcinoma of the right thigh along with right lower-extremity venous thrombosis. We comment on prognostic variables as well as discuss several theories to account for the unusual location of his choriocarcinoma.
authors.affiliation: Department of Internal Medicine, Long Island Jewish Hospital, New Hyde Park, NY, USA.
authors.forename: Ilya
authors.initials: I
authors.lastname: Blokh
authors.forename: Stanley J
authors.initials: SJ
authors.lastname: Oiseth
authors.forename: Joachim
authors.initials: J
authors.lastname: Fuks
authors.forename: Dharamuir
authors.initials: D
authors.lastname: Jain
authors.forename: Saji
authors.initials: S
authors.lastname: Eapen
authors.forename: Lydia
authors.initials: L
authors.lastname: Koulova
authors.forename: Doru
authors.initials: D
authors.lastname: Alexandrescu
authors.forename: Yuan-Yi
authors.initials: YY
authors.lastname: Li
authors.forename: Janice
authors.initials: J
authors.lastname: Dutcher
authors.forename: Peter H
authors.initials: PH
authors.lastname: Wiernik
mesh_terms: D002822:Choriocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D013848:Thigh; D020246:Venous Thrombosis / Q000209:etiology* / Q000473:pathology