Preparation of "high specific activity" radiochemical forms of vanadium, manganese and thallium for metallo-toxicological studies.
In this paper are presented the production methods for very "high specific activity" radionuclides (HSA-RN) of vanadium, manganese and thallium which have been developed in our laboratories for labelling different chemical forms of these elements present in the echo-systems in ultra-trace amounts, for metallo-toxicological and bio-kinetic studies. Use was made of both cyclotron and thermal nuclear reactor. If the nuclear reaction product has atomic number different from irradiated target, it is possible separating the radioactive nuclide from irradiated target, without addition of isotopic carrier. This kind of radionuclide is named No Carrier Added, NCA, and his specific activity, As is very high and can reach values close to the theoretical Carrier Free one, CF. The experimental determination of specific activity, chemical and radiochemical purities is mandatory for all these kinds of applications.
Bonardi
Mauro
M
Radiochemistry Laboratory, LASA, Università degli Studi di Milano and National Institute of Nuclear Physics, INFN, Via F.lli Cervi 201,1-20090 Segrate, Milano, Italy. Mauro.Bonardi@MI.INFN.IT
Birattari
Claudio
C
Groppi
Flavia
F
Gini
Luigi
L
Ghioni
Alberto
A
Mainardi
Hae Song
HS
Arginelli
Dolores
D
Gallorini
Mario
M
Rizzio
Enrico
E
Sabbioni
Enrico
E
D017357:Cyclotrons; D008345:Manganese / Q000737:chemistry; D011849:Radioactive Tracers; D011868:Radioisotopes / Q000737:chemistry*; D011876:Radionuclide Generators; D013793:Thallium / Q000737:chemistry; D013794:Thallium Radioisotopes / Q000737:chemistry; D018675:Toxicity Tests; D014131:Trace Elements / Q000032:analysis*; D014639:Vanadium / Q000737:chemistry
D011849:Radioactive Tracers; D011868:Radioisotopes; D013794:Thallium Radioisotopes; D014131:Trace Elements; D014639:Vanadium; D008345:Manganese; D013793:Thallium