title: Possibility to treat lung tuberculosis without use of rifampicin in heart transplant recipients--two cases report.
abstract: Pulmonary infections remain the leading cause of death in patients after heart transplantation. Lung tuberculosis is more common in transplant recipients than in general population. Two cases of tuberculosis are presented in patients after heart transplantation. Regarding to influence of rifampicin on immunosuppressive therapy, those patients were treated with antimycobacterial drugs except rifampicin. A cure without recurrence can be achieved with a scheme of treatment regimes without rifampicin.
authors.affiliation: Dept of Phtisiopneumonology, Silesian School of Medicine, Zabrze, Poland.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Jastrzebski
authors.forename: Michał
authors.initials: M
authors.lastname: Zakliczyński
authors.forename: Jerzy
authors.initials: J
authors.lastname: Kozielski
authors.forename: Mirosława
authors.initials: M
authors.lastname: Sioła
authors.forename: Szymon
authors.initials: S
authors.lastname: Dworniczak
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Wojdyła
authors.forename: Marian
authors.initials: M
authors.lastname: Zembala
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects* / Q000379:methods; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D012293:Rifampin; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000209:etiology*
chemical_list: D000995:Antitubercular Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D012293:Rifampin