title: [Direct MR arthrography of the wrist in comparison with arthroscopy: a prospective study on 125 patients].
abstract: OBJECTIVE
  In literature the diagnostic value of MRI for detecting lesions of the carpal ligaments and the TFCC is judged controversially. The aim of the following study is to determine the diagnostic accuracy of direct MR arthrography for depicting and staging of intraarticular lesions of the wrist.
  
  
  METHODS
  One day before undergoing arthroscopy, 125 patients suffering from wrist pain were examined with direct MR arthrography in a prospective and blinded study. A mixture of contrast medium (iodine-containing contrast medium and gadopentetate in relation 200 : 1) was injected into both radiocarpal and midcarpal joints. The following sequences were acquired on a 1.5T scanner: coronal T1-weighted SE, coronal fat-saturated T1-weighted SE, coronal T1-/T2*-DESS-3D, and sagittal T2*-weighted MEDIC. MRI results were compared with arthroscopic findings using statistical analysis (SEN = sensitivity, SPE = specificity, PPV = positive predictive value, NPV = negative predictive value, ACC = accuracy).
  
  
  RESULTS
  In comparison to arthroscopy as the accepted diagnostic gold standard, the following results were found for MR arthrography. Detection of TFCC lesions: SEN 97.1 %, SPE 96.4 %, PPV 97.1 %, NPV 96.4 %, ACC 96.8 %. Detection of complete tears of the scapholunate ligament: SEN 91.7 %, SPE 100 %, PPV 100 %, NPV 99.1%, ACC 99.2%. Detection of partial tears: SEN 62.5 %, SPE 100 %, PPV 100 %, NPV 94.8 %, ACC 95.2 %. Detection of cartilage defects: SEN 84.2 %, SPE 96.2 %, PPV 80 %, NPV 97.1 %, ACC 94.4 %. In total, only three lesions of the lunotriquetral ligament were present.
  
  
  CONCLUSIONS
  Direct MR arthrographic imaging is well suited for detecting intraarticular lesions of the wrist. The presented diagnostic results of MR arthrography are superior to the results of unenhanced MRI reported in the literature. Direct MR arthrography as a reliable diagnostic tool is strongly recommended if lesions of the scapholunate ligament and the triangular fibrocartilage complex are suspected. In contrast, an attitude of caution must be adopted in diagnosing lesions of the articular cartilage of the wrist.
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie der Herz- und Gefässklinik GmbH Bad Neustadt an der Saale. schmitt.radiologie@herzchirurgie.de
authors.forename: R
authors.initials: R
authors.lastname: Schmitt
authors.forename: G
authors.initials: G
authors.lastname: Christopoulos
authors.forename: R
authors.initials: R
authors.lastname: Meier
authors.forename: G
authors.initials: G
authors.lastname: Coblenz
authors.forename: S
authors.initials: S
authors.lastname: Fröhner
authors.forename: U
authors.initials: U
authors.lastname: Lanz
authors.forename: H
authors.initials: H
authors.lastname: Krimmer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000209:etiology; D001175:Arthrography; D001182:Arthroscopy; D002348:Carpal Bones / Q000293:injuries* / Q000473:pathology; D002358:Cartilage, Articular / Q000293:injuries* / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008023:Ligaments, Articular / Q000293:injuries* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013708:Tendon Injuries / Q000175:diagnosis*; D013710:Tendons / Q000473:pathology; D014283:Triiodobenzoic Acids; D014954:Wrist Injuries / Q000175:diagnosis*; D014955:Wrist Joint / Q000473:pathology*
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; C033300:iotrolan; D019786:Gadolinium DTPA