[Effects of dentine phosphoprotein on remineralization of demineralized dentine].
OBJECTIVE
To investigate the relationship between dentine phosphoprotein (DPP) and remineralization of demineralized dentine.


METHODS
(1) Soluble DPP was extracted with 1 mol/L NaCl from demineralized dentine and was evaluated. (2) Soluble DPP was removed with 0.1 mol/L NaCl or was not removed from demineralized dentine sections in human tooth roots. Then all sections were subjected to remineralization treatment, and remineralization degrees were compared by atomic absorption spectrum, SEM and microradiography.


RESULTS
(1) Soluble DPP was extracted with 1 mol/L NaCl. (2) Removal of soluble DPP resulted in significantly lower calcium concentration in remineralization solution (P < 0.01), less mean light-absorbed value in demineralized dentin sections by microradiography (P < 0.01).


CONCLUSIONS
Soluble DPP may have an inhibiting effect on remineralization of demineralized dentine, this study suggests that the remove of soluble DPP from root caries lesions may enhance their remineralization potential.
Luo
Song-jiang
SJ
Research Institute of Stomatology, Faculty of Stomatology, Capital Medical University, Beijing 100050, China.
Li
Yu-jing
YJ
Wan
Ling
L
Su
Ying
Y
Ge
Li-hua
LH
D000293:Adolescent; D002648:Child; D003804:Dentin / Q000737:chemistry*; D006801:Humans; D066298:In Vitro Techniques; D010750:Phosphoproteins / Q000302:isolation & purification / Q000502:physiology*; D017001:Tooth Demineralization; D014089:Tooth Remineralization
D010750:Phosphoproteins