title: Palladium-mediated three-component synthesis of furo[2,3-b]pyridones by one-pot coupling of 3-iodopyridones, alkynes, and organic halides.
abstract: [reaction: see text] The one-pot assembly of 4-alkoxy-3-iodo-2-pyridones, terminal alkynes, and organic halides has been achieved by integration of two sequential palladium-mediated cross-coupling reactions--Sonogashira and Wacker-type heteroannulation processes--and subsequent deprotection of the alkoxy group to afford furo[2,3-b]pyridones.
authors.affiliation: Laboratoire de Chimie Organique 1, CNRS UMR 5622, Université Claude Bernard, Lyon I, CPE. 43, Bd du 11 Novembre 1918, 69622 Villeurbanne, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bossharth
authors.forename: Philippe
authors.initials: P
authors.lastname: Desbordes
authors.forename: Nuno
authors.initials: N
authors.lastname: Monteiro
authors.forename: Geneviève
authors.initials: G
authors.lastname: Balme