Polycythemia vera in a dog presenting with uveitis.
A 2-year-old, castrated male, mixed-breed dog presented with a 1-month history of red eyes and intermittent vomiting and a 2-week history of polyuria and polydipsia. Bilateral anterior uveitis and active chorioretinitis in the left eye were found on ophthalmic examination. Complete blood counts demonstrated evidence of an increased red blood cell mass. Thoracic and abdominal radiographs, abdominal ultrasonography, and Doppler echocardiography were unremarkable. Serum erythropoietin level was low-normal, consistent with a diagnosis of polycythemia vera. Resolution of all systemic and ocular signs occurred, and remission was achieved following phlebotomy and treatment with oral hydroxyurea.
Gray
Heather E
HE
Department of Internal Medicine, Rowley Memorial Animal Hospital, 171 Union Street, Springfield, Massachusetts 01105, USA.
Weigand
Claire M
CM
Cottrill
Nancy B
NB
Willis
A Michelle
AM
Morgan
Rhea V
RV
D000284:Administration, Oral; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001772:Blood Cell Count / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D004285:Dogs; D004921:Erythropoietin / Q000097:blood; D006918:Hydroxyurea / Q000008:administration & dosage; D008297:Male; D011087:Polycythemia Vera / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D011859:Radiography; D014463:Ultrasonography; D014605:Uveitis / Q000209:etiology / Q000662:veterinary
D000970:Antineoplastic Agents; D004921:Erythropoietin; D006918:Hydroxyurea