[Fetal examination of first trimester abortions].
BACKGROUND
Rather few papers are about first trimesters pathology. The reason of this roots in the technical difficulties. The first trimesters pathology can not be separated from prenatal diagnostics.


OBJECTIVE
The authors summarized the molecular basis of embryology, malformations, and published cases that had been diagnosed prenatally.


METHODS
In the I. Department of Obstetrics and Gynecology, Semmelweis University in Budapest between 1995. and 2000. altogether sixty embryos 70 gms or smaller were examined.


RESULTS
Malformations included neural tube defects, disorders of twinning, body stalk defect, chromosome aberrations, hydrops, omphalocele and gastroschisis.


CONCLUSIONS
Examination of early embryos may discover many results on the fields of prenatal diagnosis and the pathomechanism of developmental abnormalities.
Marton
Tamás
T
Semmelweis Egyetem Altalános Orvostudományi Kar, I. Sz. Szülészeti és Nógyógyászati Klinika, Budapest.
Hargitai
Beáta
B
Böze
Tamás
T
Tankó
András
A
Csapó
Zsolt
Z
Szende
Béla
B
Papp
Zoltán
Z
D000022:Abortion, Spontaneous / Q000209:etiology*; D000818:Animals; D002869:Chromosome Aberrations; D002971:Cleft Lip / Q000235:genetics / Q000473:pathology; D002972:Cleft Palate / Q000235:genetics / Q000473:pathology; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology*; D006554:Hernia, Umbilical / Q000235:genetics / Q000473:pathology; D006801:Humans; D015160:Hydrops Fetalis / Q000235:genetics / Q000473:pathology; D009436:Neural Tube Defects / Q000235:genetics / Q000473:pathology; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016216:Ultrasonography, Prenatal