title: Periapical inflammation affecting coronally-inoculated dog teeth with root fillings augmented by white MTA orifice plugs.
abstract: Placement of orifice plugs has been suggested to augment the seal of conventional root canal fillings. This study assessed in vivo the efficacy of white mineral trioxide aggregate (MTA) plugs in preventing periapical inflammation subsequent to coronal inoculation of root-filled teeth. The two-rooted mandibular premolars of six beagle dogs were conventionally prepared and filled with gutta-percha and sealer. A white MTA orifice plug was placed into one canal in each tooth. Pulp chambers were inoculated with plaque except for 12 teeth (negative control), and restored. Radiographs were taken at regular intervals. At 10 months, dogs were killed and jaw blocks processed for histology. None of the roots revealed radiographic or histologic evidence of severe inflammation. Mild inflammation was observed in 17% and 39% of the roots with and without an orifice plug, respectively (McNemar, p > 0.05). Without development of severe inflammation, the seal augmentation efficacy of MTA orifice plugs could not be determined.
authors.affiliation: Discipline of Endodontics, Faculty of Dentistry, University of Toronto, Ontario, Canada.
authors.forename: Terence
authors.initials: T
authors.lastname: Mah
authors.forename: Bettina
authors.initials: B
authors.lastname: Basrani
authors.forename: João M
authors.initials: JM
authors.lastname: Santos
authors.forename: Elizeu A
authors.initials: EA
authors.lastname: Pascon
authors.forename: Leo
authors.initials: L
authors.lastname: Tjäderhane
authors.forename: Ghassan
authors.initials: G
authors.lastname: Yared
authors.forename: Herenia P
authors.initials: HP
authors.lastname: Lawrence
authors.forename: Shimon
authors.initials: S
authors.lastname: Friedman
mesh_terms: D017607:Aluminum Compounds; D000818:Animals; D017610:Calcium Compounds; D003116:Color; D003763:Dental Leakage / Q000209:etiology / Q000517:prevention & control*; D003773:Dental Plaque / Q000150:complications; D004285:Dogs; D004338:Drug Combinations; D008297:Male; D010087:Oxides; D010485:Periapical Periodontitis / Q000209:etiology / Q000517:prevention & control*; D012387:Root Canal Filling Materials; D012389:Root Canal Obturation / Q000379:methods*; D017640:Silicates; D019228:Tooth Crown / Q000382:microbiology
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate