Use of 1,4-dioxan for preparation of bupivacaine loaded PLGA microspheres with an o/w emulsion extraction process.
Sznitowska
M
M
Department of Pharmaceutical Technology, Medical University of Gdansk, Poland. msznito@farmacja.amg.gda.pl
Płaczek
M
M
D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000737:chemistry*; D002045:Bupivacaine / Q000008:administration & dosage* / Q000737:chemistry*; D004146:Dioxanes / Q000737:chemistry*; D004339:Drug Compounding; D004655:Emulsions; D019344:Lactic Acid; D008863:Microspheres; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers; D012995:Solubility
D000779:Anesthetics, Local; D004146:Dioxanes; D004655:Emulsions; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; C025223:1,4-dioxane; D002045:Bupivacaine