title: Recurrent episodes of deep vein thrombosis in a young man.
abstract: We present the case of a 32-year-old man suffering from recurrent episodes of deep vein thrombosis (DVT). He was heterozygous for the G1691A mutation in the Factor V gene. His father was heterozygous for the same mutation and had a unique episode of DVT after a fracture of the tibia. Genetic predisposition significantly influences the prevalence of thrombotic events, however, additional unknown factors may be involved in the initiation and recurrence of venous thromboembolism.
authors.affiliation: Hematology Laboratory, Unit of Mocolecular Biology, University Hospital of Ioannina, Ioannina, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Giotopoulou
authors.forename: K
authors.initials: K
authors.lastname: Giafis
authors.forename: E
authors.initials: E
authors.lastname: Dokou
authors.forename: C
authors.initials: C
authors.lastname: Tsaousi
authors.forename: N
authors.initials: N
authors.lastname: Kolaitis
authors.forename: G
authors.initials: G
authors.lastname: Vartholomatos
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D006115:Greece; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010690:Phlebography; D011152:Popliteal Vein / Q000000981:diagnostic imaging / Q000473:pathology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin