title: Pineal xanthogranuloma.
abstract: A 64-year-old man presented a large pineal cystic lesion manifesting as headache and exhibiting unusual neuroradiological findings. Magnetic resonance imaging showed a cystic lesion appearing as hyperintense on both T1- and T2-weighted images, and a nodular lesion which was hypointense on T1-and mixed intensity on T2-weighted images. The cystic mass was removed via a right occipital transtentorial approach. Histological examination disclosed that the inner surface of the cystic part consisted of bi-layered epithelial lining, portions of which had changed to stratified squamous epithelium. The solid part showed the characteristics of xanthogranuloma such as cholesterol clefts, hemosiderin-laden macrophages, and foreign body giant cells.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Kagoshima University, Kagoshima, Japan. m2040k@m3.kufm.kagoshima-u.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Takeshima
authors.forename: Maki
authors.initials: M
authors.lastname: Murayama
authors.forename: Osamu
authors.initials: O
authors.lastname: Miyanohara
authors.forename: Yo-ichi
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kuratsu
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D006099:Granuloma / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010870:Pineal Gland / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D014973:Xanthomatosis / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery