Acute pustular psoriasis complicated by leukocytoclastic vasculitis.
Acute pustular psoriasis is characterized by fiery-red erythema followed by formation of pustules. Precipitating factors include drugs, infections, pregnancy, solar irradiation, and psychological stress. We present a case of a woman who developed acute onset of pustular psoriasis precipitated by hydroxychloroquine therapy and systemic steroids. The patient's course was complicated by leukocytoclastic vasculitis presumptively caused by levofloxacin.
Welsch
Michael Jude
MJ
University of Chicago, Dept of Medicine-Section of Dermatology, 5841 S. Maryland, MC 5067, Chicago, IL 60637-1470, USA. mjudew@hotmail.com
D000208:Acute Disease; D000368:Aged; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects; D008297:Male; D011241:Prednisone / Q000009:adverse effects; D011565:Psoriasis / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*
D006886:Hydroxychloroquine; D011241:Prednisone