[Biological markers of myocardial necrosis].
New biological markers of myocardial injury have improved the management of patients with acute coronary syndromes. Among these markers, the most relevant are the cardiac troponins (troponin I and troponin T) because of their cardiospecificity, and myoglobin because of its combination of diagnostic sensitivity and usefulness for an early diagnosis. The serial analysis and combined use of both markers fulfill all diagnostic and prognostic requirements, and are helpful in indicating therapeutic strategies for acute coronary syndromes. However, these markers also have limitations, and their concentrations should always be interpreted in the light of the patient's clinical status.
Santaló Bel
Miguel
M
Complejo de Urgencias, Emergencias y Críticos. Hospital de la Santa Creu i Sant Pau. Universidad Autónoma. Barcelona. España.
Guindo Soldevila
Josep
J
Ordóñez Llanos
Jordi
J
D015415:Biomarkers / Q000097:blood*; D003327:Coronary Disease / Q000097:blood* / Q000473:pathology*; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D009206:Myocardium / Q000473:pathology*; D009211:Myoglobin / Q000097:blood; D009336:Necrosis; D014336:Troponin / Q000097:blood
D015415:Biomarkers; D009211:Myoglobin; D014336:Troponin; D003402:Creatine Kinase