title: Bilateral uveal melanoma: a series of four cases.
abstract: OBJECTIVE
  To describe the occurrence of bilateral primary choroidal melanoma in four patients.
  
  
  METHODS
  All patients attending the Liverpool Ocular Oncology Centre with uveal melanoma between January 1993 and February 2002 were identified, and those with bilateral primary choroidal melanoma were reviewed. Their presentation and management are described.
  
  
  RESULTS
  Four patients, all female, were identified. Patient 1 presented with a right juxtapapillary melanoma at the age of 64, which was treated with krypton laser and endoresection, and then when aged 73 required proton beam radiotherapy for a melanoma in her left eye. Patient 2 presented at the age of 82 with bilateral choroidal melanomas and underwent simultaneous bilateral plaque radiotherapy. Patient 3 presented with bilateral choroidal melanomas at the age of 75 and was treated initially with bilateral proton beam radiotherapy. Patient 4 was treated at the age of 54 with right plaque radiotherapy for a choroidal melanoma, and 3 years later needed plaque radiotherapy for a melanoma in her other eye.
  
  
  CONCLUSIONS
  Bilateral choroidal melanoma is possible and should be a consideration in the continuing management of patients with choroidal melanoma.
authors.affiliation: Liverpool Ocular Oncology Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK. peterandandy@hotmail.com
authors.forename: P W
authors.initials: PW
authors.lastname: Hadden
authors.forename: B E
authors.initials: BE
authors.lastname: Damato
authors.forename: I C
authors.initials: IC
authors.lastname: McKay
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002830:Choroid Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000503:physiopathology / Q000532:radiotherapy*; D008875:Middle Aged; D014792:Visual Acuity