title: A solid-state bioreactor coupled with forced aeration and pressure oscillation.
abstract: A novel design of a solid-state bioreactor, operated with periodic pressure oscillation coupled with forced aeration through the medium, gave efficient control of temperature. The evaluation of the bioreactor assembly with respect to temperature and cellulase production by Penicillium decumbens JUA 10 showed that, at 4 atm and the bed depth of 6 cm, the maximal temperature variation in the reactor was +1.5 degrees C at a set value of 30 degrees C compared with +6.8 degrees C in a static tray system. The highest cellulase and beta-glucosidase activities were 15 IU g(-1) and 51 IU g(-1) substrate dry matter at 96 h, respectively, while only 10 IU g(-1) and 24 IU g(-1) were obtained in the static tray culture system.
authors.affiliation: State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, PO Box 353, Beijing 100080, PR China. zhangxyy@sohu.com
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Zhang
authors.forename: Haitao
authors.initials: H
authors.lastname: Mo
authors.forename: Jian'an
authors.initials: J
authors.lastname: Zhang
authors.forename: Zuohu
authors.initials: Z
authors.lastname: Li
mesh_terms: D000332:Aerobiosis; D019149:Bioreactors / Q000382:microbiology*; D002480:Cellulase / Q000096:biosynthesis*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005246:Feedback; D009991:Oscillometry / Q000379:methods; D010407:Penicillium / Q000201:enzymology* / Q000378:metabolism; D010865:Pilot Projects; D011312:Pressure; D011673:Pulsatile Flow; D011786:Quality Control; D013696:Temperature; D014908:Triticum / Q000382:microbiology
chemical_list: D002480:Cellulase