title: Cerebral aneurysm regrowth and coil unraveling after incomplete Guglielmi detachable coil embolization: serial angiographical and histological findings.
abstract: A 69-year-old woman suffered subarachnoid hemorrhage due to rupture of an aneurysm at the tip of the basilar artery. The aneurysm was treated by endovascular treatment using Guglielmi detachable coils but the aneurysm dome could not be completely packed. Serial angiography at 10 and 18 months after embolization showed progressive regrowth of the aneurysm with loosening and unraveling of the packed coils. The patient died accidentally after head injury and autopsy was performed. Examination of the aneurysm showed further regrowth and "relative coil compaction" of the coil mass. Histological examination of the resected aneurysm showed no endothelialized membrane in the orifice and only minimal organized thrombus in the body of the aneurysm.
authors.affiliation: Department of Neurosurgery, Juntendo University, Izunagaoka Hospital, Tagata-gun, Shizuoka, Japan. KMORI1919@hkg.odn.ne.jp
authors.forename: Kentaro
authors.initials: K
authors.lastname: Mori
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Nakao
authors.forename: Naoaki
authors.initials: N
authors.lastname: Horinaka
authors.forename: Ryo
authors.initials: R
authors.lastname: Wada
authors.forename: Akira
authors.initials: A
authors.lastname: Hirano
authors.forename: Minoru
authors.initials: M
authors.lastname: Maeda
mesh_terms: D000368:Aged; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy*; D012008:Recurrence; D017211:Treatment Failure