K(ATP) opener-induced delayed cardioprotection: involvement of sarcolemmal and mitochondrial K(ATP) channels, free radicals and MEK1/2.
Gross
Eric R
ER
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226-3548, USA.
Peart
Jason N
JN
Hsu
Anna K
AK
Grover
Gary J
GJ
Gross
Garrett J
GJ
D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D005609:Free Radicals / Q000378:metabolism*; D019157:Ischemic Preconditioning, Myocardial; D048369:MAP Kinase Kinase 1; D048370:MAP Kinase Kinase 2; D008297:Male; D008929:Mitochondria, Heart / Q000378:metabolism*; D020929:Mitogen-Activated Protein Kinase Kinases / Q000378:metabolism*; D008954:Models, Biological; D009203:Myocardial Infarction / Q000517:prevention & control; D026902:Potassium Channel Blockers / Q000494:pharmacology; D015221:Potassium Channels; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012508:Sarcolemma / Q000378:metabolism
D005609:Free Radicals; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D000255:Adenosine Triphosphate; D011505:Protein-Tyrosine Kinases; D048369:MAP Kinase Kinase 1; D048370:MAP Kinase Kinase 2; D020929:Mitogen-Activated Protein Kinase Kinases