A new approach to the synthesis of the 5'-end substituted oligonucleotides using T4 polynucleotide kinase and gamma-amides of ATP bearing photoreactive groups.
Petrousseva
I O
IO
Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Lavrent'eva 8, Novosibirsk, 630090 Russia.
Safronov
I V
IV
Komarova
N I
NI
Kamynina
T P
TP
Lavrik
O I
OI
Khodyreva
S N
SN
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000577:Amides / Q000378:metabolism*; D000818:Animals; D017122:Bacteriophage T4 / Q000201:enzymology; D008027:Light; D008958:Models, Molecular; D009841:Oligonucleotides / Q000096:biosynthesis* / Q000737:chemistry*; D010766:Phosphorylation; D019920:Photoaffinity Labels; D010777:Photochemistry; D011116:Polynucleotide 5'-Hydroxyl-Kinase / Q000378:metabolism*
D000577:Amides; D009841:Oligonucleotides; D019920:Photoaffinity Labels; D000255:Adenosine Triphosphate; D011116:Polynucleotide 5'-Hydroxyl-Kinase