A comparison between 24-hour and 2-hour urine collection for the determination of proteinuria.
Proteinuria is one of the fundamental criteria for the diagnosis of pre-eclampsia with quantitative assessment based on the 24-hour urine protein estimation as the gold standard. This study was undertaken to determine whether a 2-hour protein estimation correlated with that of a formal 24-hour collection. Thirty women with proteinuric hypertension were recruited. There was significant correlation between the 2-hour and 24-hour urine protein levels (Pearson's correlation coefficient 0.76 (P 0.000). A positive 2-hour test was associated more closely with significant levels of 24-hour proteinuria than dipstick analysis alone. We conclude from this study that a random 2-hour sample could be used for the initial assessment of proteinuria and so avoid the delay associated with 24-hour quantification of urinary protein.
Somanathan
N
N
Royal Hallamshire Hospital, Sheffield, UK. Nandinisomanathan@hotmail.com
Farrell
T
T
Galimberti
A
A
D000328:Adult; D005260:Female; D006801:Humans; D006973:Hypertension / Q000652:urine; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000652:urine; D011247:Pregnancy; D011507:Proteinuria / Q000175:diagnosis*; D013997:Time Factors