title: Tooth by tooth survival analysis of dental health in girls with epilepsy.
abstract: OBJECTIVE
  The aim of this study was to analyse, tooth by tooth, the timing of caries attacks leading to dental restoration in girls with epilepsy.
  
  
  METHODS
  The series comprised 60 girls with epilepsy, 8-18 years old, treated in the Departments of Paediatrics or Neurology of the Oulu University Hospital. A group of healthy age matched girls served as control.
  
  
  METHODS
  A tooth by tooth survival analysis of the time between tooth eruption and caries attacks to a stage leading to the restorations of the permanent teeth was conducted retrospectively using data from the dental health records with annual examinations.
  
  
  RESULTS
  The rate of dental restorations placed due to caries was constantly higher in the girls with epilepsy than in their controls.
  
  
  METHODS
  The difference was significant between the first molars (p=<0.03), second molars (p=<0.02) and central incisors (p=<0.02) in the maxilla.
  
  
  CONCLUSIONS
  The present observation supports the hypothesis that factors related to epilepsy, the antiepileptic medication in particular, might increase the risk of caries.
authors.affiliation: Institute of Dentistry, University and University Hospital of Oulu, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Rajavaara
authors.forename: L
authors.initials: L
authors.lastname: Vainionpää
authors.forename: J
authors.initials: J
authors.lastname: Rättyä
authors.forename: M
authors.initials: M
authors.lastname: Knip
authors.forename: A
authors.initials: A
authors.lastname: Pakarinen
authors.forename: J
authors.initials: J
authors.lastname: Isojärvi
authors.forename: M
authors.initials: M
authors.lastname: Larmas
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000927:Anticonvulsants / Q000009:adverse effects; D016022:Case-Control Studies; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000209:etiology* / Q000628:therapy; D003793:Dental Restoration, Permanent; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007180:Incisor / Q000473:pathology; D008437:Maxilla; D008963:Molar / Q000473:pathology; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D016019:Survival Analysis; D014070:Tooth / Q000473:pathology*; D014078:Tooth Eruption / Q000502:physiology
chemical_list: D000927:Anticonvulsants