title: A pediatric case of sclerodermatous chronic graft-versus-host disease.
abstract: We report a rare case of sclerodermatous chronic graft-versus-host disease (GVHD) in a 6-year-old boy that occurred after bone marrow transplantation for his aplastic anemia. The clinical manifestation and histopathologic findings were typical of scleroderma. Although various kinds of treatment have been tried for scleroderma, no established therapy exists. Furthermore, treating this disease is even more difficult in children. In the future, clarification of the pathogenesis of chronic GVHD and establishment of therapy will be necessary.
authors.affiliation: Department of Dermatology, Kagoshima University, Faculty of Medicine, Kagoshima, Japan. ken0913@m2.kufm.kagoshima-u.ac.jp
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Terasaki
authors.forename: Takuro
authors.initials: T
authors.lastname: Kanekura
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Setoyama
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Kanzaki
mesh_terms: D000741:Anemia, Aplastic / Q000601:surgery*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D002908:Chronic Disease; D006086:Graft vs Host Disease / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D045743:Scleroderma, Diffuse / Q000209:etiology* / Q000473:pathology* / Q000628:therapy