title: [Splenic artery embolization for the treatment of hypersplenism in hemophilic, HIV-1 and HCV seropositive patients].
abstract: Thrombocytopenia is an important and common hematological abnormality in patients with HIV-1/HCV coinfection. Splenomegaly is a frequent finding in these patients and usually causes hypersplenism and thrombocytopenia. We analyzed the clinical results of a minimal invasive treatment (splenic artery embolization) for thrombocytopenia secondary to hypersplenism and refractory to other therapies in two hemophiliac patients, HIV seropositive and with cirrhosis due to chronic HCV infection. The results suggest that splenic artery embolization is a safe, relatively atraumatic and effective method for the treatment of splenomegaly and hypersplenism in selected patients with HIV-1/HCV coinfection.
authors.affiliation: Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires. marcelocorti@ciudad.com.ar
authors.forename: Marcelo E
authors.initials: ME
authors.lastname: Corti
authors.forename: María F
authors.initials: MF
authors.lastname: Villafañe
authors.forename: Francisco
authors.initials: F
authors.lastname: Suárez Anzorena
authors.forename: Jorge
authors.initials: J
authors.lastname: Daruich
authors.forename: Raúl
authors.initials: R
authors.lastname: Pérez Bianco
authors.forename: Miguel
authors.initials: M
authors.lastname: Candela
authors.forename: Pedro
authors.initials: P
authors.lastname: Ferraina
authors.forename: Miguel
authors.initials: M
authors.lastname: Tezanos Pinto
mesh_terms: D000328:Adult; D004621:Embolization, Therapeutic; D015658:HIV Infections / Q000150:complications; D015497:HIV-1; D006467:Hemophilia A / Q000150:complications* / Q000821:virology; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D006971:Hypersplenism / Q000150:complications / Q000601:surgery / Q000628:therapy*; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D013156:Splenectomy; D013157:Splenic Artery; D013921:Thrombocytopenia / Q000209:etiology