title: Intoxication of Crotalaria pallida seeds to growing broiler chicks.
abstract: The adverse effects of feeding Crotalaria pallida (CP) seeds to chicks was investigated in a 21-day randomized trial of 4 dietary treatments (control, 1,2 and 3% ground CP seeds). Mortality rates in birds fed 0, 1, 2, and 3% dietary CP were 0, 2.1, 6.2, and 16.7%, respectively. Body weight gain and feed efficiency were adversely affected by all levels of inclusion of CP seeds, but feed intake was decreased only by dietary levels of 2 and 3%. Dietary CP of 2 and 3% increased the relative weight of lung, heart and spleen. Relative liver weight was increased by 2% dietary CP, but decreased by 3% CP. At day 14, serum GGT was increased by 2 and 3% dietary CP; serum ALT was significantly increased by 3% CP. No differences in ALT, AST or GGT were observed at day 21. Dietary levels equal to or greater than 1% CP are toxic for growing broiler chicks.
authors.affiliation: Laboratorio de Toxicología, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogotá DC, Colombia.
authors.forename: G J
authors.initials: GJ
authors.lastname: Diaz
authors.forename: L P
authors.initials: LP
authors.lastname: Roldán
authors.forename: A
authors.initials: A
authors.lastname: Cortés
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000821:Animal Feed; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000662:veterinary*; D002645:Chickens; D029864:Crotalaria; D008111:Liver Function Tests / Q000662:veterinary; D008297:Male; D010939:Plant Poisoning / Q000209:etiology / Q000662:veterinary*; D011201:Poultry Diseases / Q000139:chemically induced* / Q000401:mortality / Q000473:pathology; D012639:Seeds / Q000633:toxicity; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase