title: [Primary central nervous system lymphoma in a patient with systemic lupus erythematosus].
abstract: A 36 year-old woman with systemic lupus erythematosus was admitted to our hospital with headache, brachiocrural hemiparesis and hemianesthesia. She had been treated with prednisone and cyclophosphamide. CT scan and MRI revealed a 15 mm nodular mass enhanced with gadolinium in left frontal convexity. CNS biopsy was performed and a diffuse large B-cell lymphoma was diagnosed. She was treated with radiation therapy without response and died. There are few reports of erythematosus systemic lupus associated with primary central nervous system lymphoma.
authors.affiliation: Servicio de Inmunología, Instituto de Investigaciones Médicas Alfredo Lanari, Combatientes de Malvinas 3150, 1427 Buenos Aires, Argentina.
authors.forename: Cecilia N
authors.initials: CN
authors.lastname: Pisoni
authors.forename: Alejandro R
authors.initials: AR
authors.lastname: Grinberg
authors.forename: José L
authors.initials: JL
authors.lastname: Plana
authors.forename: Roberto D
authors.initials: RD
authors.lastname: Freue
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Manni
authors.forename: Leonardo
authors.initials: L
authors.lastname: Paz
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008279:Magnetic Resonance Imaging
chemical_list: D007166:Immunosuppressive Agents