title: Comparison of the mosquito-repelling efficacy of methyl neodecanamide (MNDA) to that of Deet.
abstract: The objective of this small pilot study was to assess the mosquito-repelling efficacy of methyl neodecanamide (MNDA) relative to N,N-diethyl-3-methylbenzamide (Deet) against Anopheles stephensi, Culex quinquefasciatus, and Aedes aegypti under controlled laboratory conditions. In this study, subjects inserted both forearms (sham- and repellent-treated) into a test chamber containing 50 female mosquitoes. The number of mosquitoes landing on or probing each forearm during the 5-minute "forced-choice" test session was recorded each hour for a total of eight hours. Effectiveness was calculated according to Abbott's formula. Experimental results indicate that topical application of 1% MNDA provided significantly better protection and a broader spectrum of repellency than application of 1% Deet against the three species of mosquitoes. These promising results support further study of MNDA as a topical mosquito repellent.
authors.affiliation: Colgate-Palmolive Company, 909 River Road, Piscataway, NJ 08854, USA.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Polefka
authors.forename: Li-Jung
authors.initials: LJ
authors.lastname: Liang
authors.forename: Taracad Narayanan
authors.initials: TN
authors.lastname: Ananthakrishnan
mesh_terms: D000473:Alkanes; D000577:Amides; D000818:Animals; D009033:Culicidae / Q000145:classification; D003671:DEET; D005260:Female; D006801:Humans; D007302:Insect Repellents; D010865:Pilot Projects; D013045:Species Specificity
chemical_list: D000473:Alkanes; D000577:Amides; D007302:Insect Repellents; C477079:methyl neodecanamide; D003671:DEET