title: Analysis of the interaction between the transcription factor sigmaG and the anti-sigma factor SpoIIAB of Bacillus subtilis.
abstract: The activation of sigma(G), a transcription factor, in Bacillus subtilis is coupled to the completion of engulfment during sporulation. SpoIIAB, an anti-sigma factor involved in regulation of sigma(F), is also shown to form a complex with sigma(G) in vitro. SpoIIAA, the corresponding anti-anti-sigma factor, can disrupt the SpoIIAB:sigma(G) complex, releasing free sigma(G). The data suggest the existence of an as-yet-unknown mechanism to keep sigma(G) inactive prior to engulfment.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.
authors.forename: Louise
authors.initials: L
authors.lastname: Evans
authors.forename: Joanna
authors.initials: J
authors.lastname: Clarkson
authors.forename: Michael D
authors.initials: MD
authors.lastname: Yudkin
authors.forename: Jeff
authors.initials: J
authors.lastname: Errington
authors.forename: Andrea
authors.initials: A
authors.lastname: Feucht
mesh_terms: D001412:Bacillus subtilis / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D012808:Sigma Factor / Q000378:metabolism*; D013171:Spores, Bacterial; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D012808:Sigma Factor; C030069:spore-specific proteins, Bacillus