title: The salicylic acid loop in plant defense.
abstract: Salicylic acid is an important signal molecule in plant defense. In the past two years, significant progress has been made in understanding the mechanism of salicylic-acid biosynthesis and signaling in plants. A pathway similar to that found in some bacteria synthesizes salicylic acid from chorismate via isochorismate. Salicylic-acid signaling is mediated by at least two mechanisms, one requiring the NON-EXPRESSOR OF PR1 (NPR1) gene and a second that is independent of NPR1. Feedback loops involving salicylic acid modulate upstream signals. These feedback loops may provide a point for integrating developmental, environmental and other defense-associated signals, and thus fine-tune the defense responses of plants.
authors.affiliation: Division of Biology, and The Molecular, Cellular and Developmental Biology Program, 303 Ackert Hall, Kansas State University, 66506-4901, Manhattan, Kansas, USA. Shah@ksu.edu
authors.forename: Jyoti
authors.initials: J
authors.lastname: Shah
mesh_terms: D029681:Arabidopsis Proteins / Q000502:physiology; D018521:Plant Physiological Phenomena; D020156:Salicylic Acid / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; C105496:NPR1 protein, Arabidopsis; D020156:Salicylic Acid