Adaptive force generation for precision-grip lifting by a spectral timing model of the cerebellum.
We modeled adaptive generation of precision grip forces during object lifting. The model presented adjusts reactive and anticipatory grip forces to a level just above that needed to stabilize lifted objects in the hand. The model obeys principles of cerebellar structure and function by using slip sensations as error signals to adapt phasic motor commands to tonic force generators associated with output synergies controlling grip aperture. The learned phasic commands are weight- and texture-dependent. Simulations of the new circuit model reproduce key aspects of experimental observations of force application. Over learning trials, the onset of grip force buildup comes to lead the load force buildup, and the rate-of-rise of grip force, but not load force, scales inversely with the friction of the object.
Ulloa
Antonio
A
Department of Cognitive & Neural Systems, Boston University, 677 Beacon Street, Boston, MA 02215, USA. antonio.ulloa@nih.gov
Bullock
Daniel
D
Rhodes
Bradley J
BJ
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009044:Motor Cortex / Q000502:physiology