title: Concerted interaction between conjugated double bond CHs and multiple OHs in polyene macrolide antibiotic chainin: weak =C-H...O interactions responsible for intrinsic molecular assembly.
abstract: The concerted interactions observed between five conjugated double bond CHs and four hydroxy Os in the crystal of chainin, a polyene macrolide antibiotic, clarified the existence of unprecedented, weak =C-H...O interactions, which is important for forming its intrinsic molecular assembly.
authors.affiliation: Department of Physical Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, Japan.
authors.forename: Yasuko
authors.initials: Y
authors.lastname: In
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Ohishi
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Ishida
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Igarashi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism*; D003460:Crystallization; D006860:Hydrogen Bonding; D006878:Hydroxides / Q000378:metabolism*; D007783:Lactones / Q000737:chemistry*; D018942:Macrolides; D015394:Molecular Structure
chemical_list: D000900:Anti-Bacterial Agents; D006878:Hydroxides; D007783:Lactones; D018942:Macrolides; C000465:chainin; C031356:hydroxide ion