title: Factors associated with therapy noncompliance in type-2 diabetes patients.
abstract: OBJECTIVE
  To identify the frequency and factors associated with therapy noncompliance in type-2 diabetes mellitus patients.
  
  
  METHODS
  A cross-sectional study was carried out in 79 patients with type-2 diabetes mellitus seen in major hospitals of Mexico City. Patients were visited at home, from March 1998 to August 1999, to measure compliance with prescribed therapy. Complying patients were defined as those taking at least 80% of their pills or 80% of their corresponding insulin dose. The degree of compliance with therapy components (diet, amount of exercise, and keeping appointments) was measured.
  
  
  RESULTS
  The average age of study subjects was 59 years (SD 11 years); 73% (n = 58) were female subjects. The overall frequency of noncompliance was 39%. Noncompliance rates were: 62% for dietary recommendations, 85% for exercise, 17% for intake of oral hypoglycemic medication, 13% for insulin application, and 3% for appointment keeping. Hypertension plus obesity was the only factor significantly associated with noncompliance (OR 4.58, CI 95% 1.0, 22.4, p = 0.02).
  
  
  CONCLUSIONS
  The frequency of therapy noncompliance was very high, especially for diet and exercise.
authors.affiliation: Instituto Nacional de Perinatología, México, DF, México.
authors.forename: Lizbeth
authors.initials: L
authors.lastname: Hernández-Ronquillo
authors.forename: José Francisco
authors.initials: JF
authors.lastname: Téllez-Zenteno
authors.forename: Juan
authors.initials: J
authors.lastname: Garduño-Espinosa
authors.forename: Erick
authors.initials: E
authors.lastname: González-Acevez
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000178:diet therapy / Q000188:drug therapy / Q000523:psychology* / Q000628:therapy; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012959:Socioeconomic Factors; D016312:Treatment Refusal / Q000706:statistics & numerical data*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin