[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
We report a case of bulla infection caused by Mycobacterium fortuitum. The patient was a 66 year-old female associated with interstitial pneumonitis. The chest X-ray film showed cavities with thick walls and niveau formation, which initially suggested pulmonary abscesses. The chest CT scan showed infiltrative shadows surrounding multiple bullae. Smears and cultures of the sputum were repeatedly positive for mycobacteria, which was identified to be M. fortuitum. By chemotherapy with imipenem/cilastatin sodium, clarithromycin, levofloxacin, and minocycline on the basis of susceptibility test, sputum converted to negative within 2 months, abnormal shadows on the roentgenogram and laboratory data showed improvement. There are no signs of recurrence after completion of the treatment for 12 months.
Hisamori
Shigeo
S
Department of Respiratory Medicine, Tenri Hospital.
Oida
Kazukiyo
K
Taguchi
Yoshio
Y
Tanaka
Eisaku
E
Inoue
Tetsuro
T
Katoh
Kouji
K
Sakuramoto
Minoru
M
Minaguchi
Masayoshi
M
Maeda
Yuuji
Y
Maniwa
Koh
K
Terada
Kunihiko
K
Ishimaru
Hiroyasu
H
Hata
Kazuhiro
K
D000368:Aged; D001768:Blister / Q000188:drug therapy; D015377:Cilastatin / Q000008:administration & dosage*; D000077728:Cilastatin, Imipenem Drug Combination; D017291:Clarithromycin / Q000008:administration & dosage*; D004338:Drug Combinations; D004359:Drug Therapy, Combination / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage*; D064704:Levofloxacin; D017563:Lung Diseases, Interstitial / Q000150:complications; D008911:Minocycline / Q000008:administration & dosage; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D019907:Mycobacterium fortuitum; D015242:Ofloxacin / Q000008:administration & dosage; D011656:Pulmonary Emphysema / Q000188:drug therapy*
D004338:Drug Combinations; D015377:Cilastatin; D064704:Levofloxacin; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination; D015242:Ofloxacin; D008911:Minocycline; D017291:Clarithromycin