title: A young infant with musicogenic epilepsy.
abstract: Musicogenic epilepsy is a relatively rare form of epilepsy. In its pure form, it is characterized by epileptic seizures that are provoked exclusively by listening to music. The usual type of seizure is partial complex or generalized tonic-clonic. Precipitating factors are quite specific, such as listening to only one composition or the actual playing of music on an instrument. However, simple sound also can be a trigger. We report a 6-month-old infant with musicogenic epilepsy. She manifested right-sided focal seizures with occasional generalization. The seizures were frequently triggered by loud music, especially that by the Beatles. The interictal electroencephalography results were normal. Ictal spikes were present throughout the left temporal area during continuous electroencephalograpic monitoring. Brain magnetic resonance imaging results were normal, whereas single-photon emission computed tomography of the brain revealed hypoperfusion of the left temporal area. The young age and epileptogenic left temporal lobe lesion in this patient with musicogenic epilepsy were unusual characteristics. Theoretically, three levels of integration are involved in music processing in the brain. The involved integration of this infant's brain may be the sensory level rather than the emotional level. Nevertheless, the personal musicality and musical style of the Beatles might play an important role in this patient's epilepsy.
authors.affiliation: Division of Pediatric Neurology, Department of Pediatrics, Chang Gung Children's Hospital at Linkou, 5 Fu-Shin Street, Kweishan 333, Taoyuan, Taiwan.
authors.forename: Kuang-Lin
authors.initials: KL
authors.lastname: Lin
authors.forename: Huei-Shyong
authors.initials: HS
authors.lastname: Wang
authors.forename: Pan-Fu
authors.initials: PF
authors.lastname: Kao
mesh_terms: D004569:Electroencephalography / Q000379:methods; D020195:Epilepsy, Reflex / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008297:Male; D009146:Music; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods