Starvation-induced impairment of metabolism in a freshwater catfish.
Starvation induced changes in citrate synthase (CS), glucose-6-phosphate dehydrogenase (G6-PDH), lactate dehydrogenase (LDH), DNA, RNA, RNA/DNA ratio and protein were studied in the freshwater catfish Clarias batrachus. Starvation gradually decreased the activity of CS, G6-PDH and LDH in brain, liver and skeletal muscle of the freshwater catfish. The maximum reduction in these enzyme activities upto 35-45% was observed after 35 days of fasting. This shows substantial decline in aerobic and biosynthetic capacity during starvation period. DNA, RNA, RNA/DNA ratio and protein contents were also reduced from 40-67% which reflects reduction in an overall capacity of the protein synthesis. Starvation-induced macromolecular changes indicate impairment of metabolism in fish.
Tripathi
Ghanshyam
G
Department of Zoology, J. N. V. University, Jodhpur-342001, India. drgst@rediffmail.com
Verma
Priyanka
P
D000064:Acclimatization; D000105:Acetyl Coenzyme A / Q000378:metabolism; D000818:Animals; D001824:Body Constitution; D001921:Brain / Q000201:enzymology; D002950:Citrate (si)-Synthase / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D005618:Fresh Water; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D007059:Ictaluridae / Q000378:metabolism*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D018482:Muscle, Skeletal / Q000201:enzymology; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D013217:Starvation
D009243:NAD; D009249:NADP; D012313:RNA; D000105:Acetyl Coenzyme A; D004247:DNA; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D002950:Citrate (si)-Synthase