[A case of advanced gastric cancer with bone metastases and DIC responding to oral administration of TS-1].
The patient was a 71-year-old man whose chief complaints were staggering and fatigue. As a result of various examinations, he was diagnosed with advanced gastric cancer, Borrmann 3, with disseminated intravascular coagulation (DIC) and bone metastases. The DIC was treated with oral administration of TS-1 (120 mg/day). Furthermore, both the primary gastric tumor and metastatic bone lesions were reduced in size by the treatment with TS-1. TS-1 appears to be an effective therapeutic agent for advanced gastric cancer with DIC or bone metastases.
Omatsu
Tatsushi
T
First Dept. of Internal Medicine, Kyoto Prefectural University of Medicine.
Ichikawa
Hiroshi
H
Kawahito
Yutaka
Y
Ashihara
Eiji
E
Yamamoto
Aihiro
A
Kadoya
Masatoshi
M
Takegami
Toru
T
Takanashi
Yoshiaki
Y
Naito
Yuji
Y
Yoshida
Norimasa
N
Sugino
Shigeru
S
Yoshikawa
Toshikazu
T
D000284:Administration, Oral; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D018279:Carcinoma, Signet Ring Cell / Q000188:drug therapy* / Q000556:secondary*; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage*; D011725:Pyridines / Q000008:administration & dosage*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000008:administration & dosage*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid