title: The ancestry of segmentation.
abstract: Recent studies of segmentation in the spider suggest that the ancestral vertebrate and arthropod segmentation mechanisms utilized the Notch signaling pathway and bolster the argument that segmentation is an ancestral feature of all bilaterians.
authors.affiliation: Department of Integrative Biology, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA.
authors.forename: Nipam H
authors.initials: NH
authors.lastname: Patel
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000235:genetics* / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics; D019143:Evolution, Molecular; D018507:Gene Expression Regulation, Developmental; D019476:Insect Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D008648:Mesoderm / Q000378:metabolism; D010802:Phylogeny; D051880:Receptors, Notch; D015398:Signal Transduction; D019170:Somites / Q000166:cytology / Q000378:metabolism*; D013112:Spiders / Q000196:embryology / Q000235:genetics; D014714:Vertebrates / Q000235:genetics / Q000378:metabolism
chemical_list: D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; C497759:N protein, Drosophila; D051880:Receptors, Notch