Cardiac toxicity caused by Achyranthes aspera.
A 57-y-old man took over 1000 ml of a decoction made from Acyranthes aspera and was found unconscious in his bathroom. Hypotension and bradycardia were noted. The patient recovered 4 d later after dopamine and supportive care. There was no further cardiac abnormalities noted in serial cardiac examinations. We suggest that Achyranthes aspera causes a dose-related transient cardiovascular toxicity.
Han
Shih-Tsung
ST
Department of Emergency Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan.
Un
Chih-Chuan
CC
D029044:Achyranthes / Q000633:toxicity*; D001168:Arthritis / Q000188:drug therapy; D002303:Cardiac Output, Low / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D002316:Cardiotonic Agents / Q000008:administration & dosage; D003128:Coma / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D003422:Critical Care; D003937:Diagnosis, Differential; D004298:Dopamine / Q000008:administration & dosage; D062787:Drug Overdose / Q000175:diagnosis / Q000473:pathology; D004638:Emergency Treatment; D015600:Glasgow Coma Scale; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged
D002316:Cardiotonic Agents; D004298:Dopamine