[Thyroid function in patients with Yusho].
To evaluate chronic effect of polychlorinated biphenyl (PCB) on thyroid functions, thyroid hormone levels were studied in 115 patients with Yusho in 2002. Serum level of thyroid stimulating hormone (TSH) was elevated in 13 cases (11.3%). All of them showed normal triiodothyronine (T3) and thyroxine (T4) levels, and regarded as latent hypothyroidism. There were no significant correlations between blood PCB concentrations and TSH levels, T3 levels or T4 levels. We conclude that abnormality of TSH levels in patients with Yusho is frequent, but it may not be associated with blood PCB concentration.
Tsuji
Hiroshi
H
Department of Internal Medicine, Kitakyushu-Tsuyazaki Hospital, Fukuoka 811-3307, Japan.
Ito
Yasuo
Y
D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D005260:Female; D005506:Food Contamination; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012275:Oryza / Q000506:poisoning*; D010938:Plant Oils / Q000506:poisoning*; D011078:Polychlorinated Biphenyls / Q000097:blood / Q000506:poisoning*; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D015415:Biomarkers; D010938:Plant Oils; D014284:Triiodothyronine; D013972:Thyrotropin; D011078:Polychlorinated Biphenyls; D013974:Thyroxine