Gaze-centered updating of visual space in human parietal cortex.
Single-unit recordings have identified a region in the posterior parietal cortex (PPC) of the monkey that represents and updates visual space in a gaze-centered frame. Here, using event-related functional magnetic resonance imaging, we identified an analogous bilateral region in the human PPC that shows contralateral topography for memory-guided eye movements and arm movements. Furthermore, when eye movements reversed the remembered horizontal target location relative to the gaze fixation point, this PPC region exchanged activity across the two cortical lobules. This shows that the human PPC dynamically updates the spatial goals for action in a gaze-centered frame.
Medendorp
W Pieter
WP
Canadian Institutes of Health Research Group on Action and Perception, Centre for Vision Research, York University, Toronto, Ontario, Canada, M3J 1P3. p.medendorp@nici.kun.nl
Goltz
Herbert C
HC
Vilis
Tutis
T
Crawford
J Douglas
JD
D000328:Adult; D001132:Arm / Q000502:physiology; D001931:Brain Mapping / Q000379:methods; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory; D009068:Movement / Q000502:physiology; D010296:Parietal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology; D013028:Space Perception / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*