title: Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives.
abstract: [reaction: see text] Novel synthetic methods of both ortho-alkenylated aromatic ketones and isoquinoline derivatives have been developed through the Rh(I)-catalyzed direct ortho-alkenylation of common aromatic ketimines with alkynes. Furthermore, a highly efficient one-pot synthesis of isoquinoline derivatives was achieved by simply mixing aromatic ketone, benzylamine, and alkyne under a Rh(I) catalyst.
authors.affiliation: Department of Chemistry, Yonsei Univeristy, Seoul 120-749, Korea.
authors.forename: Sung-Gon
authors.initials: SG
authors.lastname: Lim
authors.forename: Jun Hee
authors.initials: JH
authors.lastname: Lee
authors.forename: Choong Woon
authors.initials: CW
authors.lastname: Moon
authors.forename: Jun-Bae
authors.initials: JB
authors.lastname: Hong
authors.forename: Chul-Ho
authors.initials: CH
authors.lastname: Jun