title: Combinational use of conformal and intensity-modulated beams in radiotherapy planning.
abstract: Intensity-modulated (IM) beam profiles computed by inverse-planning systems tend to be complex and may have multiple spatial minima and maxima. In addition to the structure originating from the treatment objectives, beam profiles might contain stochastic structure or noise and numerical artefacts, which present certain practical difficulties. The combinational use of conformal and intensity-modulated beams could be a different method of making the total fluence distribution less noisy and deliverable without compromising the advantages of IMRT. The investigation of this possibility provided the basis for this paper. A treatment-planning study was performed to compare plans combining modulated and unmodulated beams with a 5-field, equally spaced, full IMRT plan for treating the prostate and seminal vesicles in three patients. Beam angles for this study were 0 degrees, 72 degrees, 144 degrees, 216 degrees and 288 degrees. Additionally, a study was performed on a patient with a different beam arrangement (36 degrees, 108 degrees, 180 degrees, 252 degrees, 324 degrees) from the first study to test the obtained results. This study has demonstrated that it is possible to substitute up to two conformal beams in the originally full IMRT plan when carefully selecting the conformal beam angles. Making the anterior beam (0 degrees) and an anterior oblique beam (between 0 degrees and 90 degrees) conformal leads to a reduction in the total number of monitor units and segments of about 15% and 39%, respectively. Additionally, these two open fields can be used for simpler treatment verification.
authors.affiliation: Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK. Catherine.Coolens@icr.ac.uk
authors.forename: Catherine
authors.initials: C
authors.lastname: Coolens
authors.forename: Steve
authors.initials: S
authors.lastname: Webb
authors.forename: Phil M
authors.initials: PM
authors.lastname: Evans
authors.forename: Joao
authors.initials: J
authors.lastname: Seco
mesh_terms: D001699:Biometry; D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D020266:Radiotherapy, Conformal / Q000379:methods* / Q000706:statistics & numerical data