title: 1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin.
abstract: It has been found that 1-methylnicotinamide (MNA+), a metabolite of nicotinamide, possesses significant anti-inflammatory properties. MNA+ is chemically stable, non-toxic and well tolerated. MNA+ can be used to treat wide variety of diseases and disorders and the use of this compound provides certain advantages over the use of nicotinamide.
authors.affiliation: Institute of Applied Radiation Chemistry, Technical University, Zeromskiego 116, PL 90-924 Lódź, Poland. jgebicki@ck-sg.p.lodz.pl
authors.forename: Jerzy
authors.initials: J
authors.lastname: Gebicki
authors.forename: Anna
authors.initials: A
authors.lastname: Sysa-Jedrzejowska
authors.forename: Jan
authors.initials: J
authors.lastname: Adamus
authors.forename: Anna
authors.initials: A
authors.lastname: Woźniacka
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Rybak
authors.forename: Jacek
authors.initials: J
authors.lastname: Zielonka
mesh_terms: D000287:Administration, Topical; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000737:chemistry / Q000378:metabolism*; D003872:Dermatitis / Q000378:metabolism / Q000517:prevention & control; D004311:Double-Blind Method; D005782:Gels; D006801:Humans; D009536:Niacinamide / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*; D010865:Pilot Projects
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005782:Gels; D009536:Niacinamide; C024058:N(1)-methylnicotinamide