Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Anderson
Daniel G
DG
Department of Chemical Engineering, Room E25-342, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Lynn
David M
DM
Langer
Robert
R
D000818:Animals; D001331:Automation; D019556:COS Cells; D002412:Cations / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D002520:Cercopithecidae; D004353:Drug Evaluation, Preclinical; D005786:Gene Expression Regulation; D015316:Genetic Therapy / Q000379:methods*; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D014162:Transfection / Q000379:methods*
D002412:Cations; D011108:Polymers