title: [Pancreatoduodenal resection in treatment of cancer of pancreatic head and periampullar zone].
abstract: Results of 120 pancreatoduodenal resections are analyzed. Early postoperative period complications were seen in 51 (42.5%) patients. Overall lethality during 30 days after surgery was 13.3%. Over the last decade lethality reduced to 5%. Life time was studied in 91 patients with cancer of the pancreas (PS) and periampullar zone (PAZ) with Kaplan-Meyer method. Median of life of patients with cancer of PS was 14 months, Vater's papilla (VP)--37 months, terminal part of common bile duct (TPCBD)--30 months, duodenum--30 months. One-, 3-, 5-year survival in cancer of PS was 53, 11 and 3%, in cancer of VP--80, 50 and 31%, in cancer of TPCBD--80, 20% and 0, in duodenal cancer--80, 50 and 33%, respectively. Prognosis factors correlating with the survival were following: 1) primary location of tumor; 2) size of tumor; 3) radicality of surgery; 4) regional lymphatic metastases; 5) invasion of vessels by tumor; 6) index of oncomarker CA 19-9. Early diagnosis of cancer of PS and PAZ, optimization of surgical policy and techniques, using other methods in complex improve results of pancreatoduodenal resections.
authors.forename: R A
authors.initials: RA
authors.lastname: Alibegov
authors.forename: S A
authors.initials: SA
authors.lastname: Kasum'ian
authors.forename: A V
authors.initials: AV
authors.lastname: Borsukov
authors.forename: O A
authors.initials: OA
authors.lastname: Sergeev
authors.forename: O D
authors.initials: OD
authors.lastname: Varchuk
authors.forename: V V
authors.initials: VV
authors.lastname: Shemetov
mesh_terms: D014670:Ampulla of Vater / Q000473:pathology / Q000601:surgery*; D004386:Duodenum / Q000601:surgery*; D006801:Humans; D010179:Pancreas / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000601:surgery*; D011183:Postoperative Complications