title: A non-surgical jugular catheterization technique for multiple blood sampling in cats.
abstract: In order to perform pharmacokinetic studies involving multiple blood sampling, repeated at variable intervals of time, a simple and reliable non-surgical jugular catheterization technique was developed. Six cats were catheterized 48 times using an indwelling through-the-needle type catheter (22G and 20.3 cm) placed into the jugular vein through an over-the-needle type (20G and 32 mm). Catheters remained in place for 1-13 days (median 3 days) without loss of patency until removal. Each jugular was catheterized a range of 2-6 times, with a total indwelling time of 4-33 days. No clinical signs of phlebitis, thrombosis or sepsis were observed either during or after the studies. This technique allows an easy, non-painful, non-stressful blood withdrawal during extended sampling periods, with minimal damage of the veins.
authors.affiliation: Area de Farmacología, Departamento de Fisiopatología y Etiopatogenia, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Chorroarín 280 (1427), Buenos Aires, Argentina. albarell@fvet.uba.ar
authors.forename: G A
authors.initials: GA
authors.lastname: Albarellos
authors.forename: R R
authors.initials: RR
authors.lastname: Bonafine
authors.forename: V E
authors.initials: VE
authors.lastname: Kreil
authors.forename: L A
authors.initials: LA
authors.lastname: Ambros
authors.forename: L
authors.initials: L
authors.lastname: Montoya
authors.forename: R E
authors.initials: RE
authors.lastname: Hallu
mesh_terms: D000818:Animals; D001800:Blood Specimen Collection / Q000379:methods / Q000662:veterinary*; D002404:Catheterization / Q000379:methods / Q000662:veterinary*; D002415:Cats; D005260:Female; D007601:Jugular Veins; D008297:Male; D010599:Pharmacokinetics