RNA silencing bridging the gaps in wheat extracts.
In plants, RNA silencing plays important roles in antiviral defence, genome integrity and development. This process involves nucleotide sequence-specific interactions that are mediated by small RNA molecules of 21-25 nucleotides. Although the core biochemical reactions of RNA silencing have been well characterized in animals, such information was crucially missing in plants. Recent work now addresses this question and reveals an overall similarity between the plant and animal RNA-silencing pathways, as well as some intriguing plant-specific aspects.
Voinnet
Olivier
O
Institut de Biologie Moléculaire des Plantes du CNRS 12, Rue du Général Zimmer, 67084 Strasbourg Cedex, France. olivier.voinnet@ibmp-ulp.u-strasbg.fr
D000818:Animals; D004722:Endoribonucleases / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D010936:Plant Extracts; D034622:RNA Interference; D012330:RNA, Double-Stranded / Q000235:genetics / Q000378:metabolism; D018749:RNA, Plant / Q000235:genetics / Q000378:metabolism; D034741:RNA, Small Interfering / Q000378:metabolism; D043244:Ribonuclease III; D014908:Triticum / Q000201:enzymology / Q000235:genetics*
D035683:MicroRNAs; D010936:Plant Extracts; D012330:RNA, Double-Stranded; D018749:RNA, Plant; D034741:RNA, Small Interfering; D004722:Endoribonucleases; D043244:Ribonuclease III