Mediators in HIV-associated cardiovascular disease: a focus on cytokines and genes.
As longevity increases in HIV-infected individuals, late effects such as cardiovascular disease and, more specifically, symptomatic heart failure are emerging as leading health issues. In the present review, we discuss possible cytokine and gene-mediated effects on HIV-associated cardiovascular illness that may play a role in diagnosis, management, and therapy of HIV-associated heart failure.
Fisher
Stacy D
SD
Department of Medicine, Cardiology Unit, University of Rochester Medical Center, Rochester, New York 14642, USA.
Bowles
Neil E
NE
Towbin
Jeffrey A
JA
Lipshultz
Steven E
SE
D015526:AIDS Dementia Complex / Q000235:genetics; D009202:Cardiomyopathies / Q000235:genetics / Q000821:virology*; D016207:Cytokines / Q000502:physiology*; D015658:HIV Infections / Q000150:complications* / Q000235:genetics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000235:genetics / Q000821:virology; D007116:Immunization, Passive; D009205:Myocarditis / Q000628:therapy; D018487:Ventricular Dysfunction, Left / Q000821:virology
D016207:Cytokines