[Anemia in cancer patients before treatment].
Thirty per cent of cancer patients suffer from anemia before any treatment. This anemia is caused by haematopoiesis troubles related to cytokines production and by endogenous erythropoietin deficiency. Clinically, its symptoms, including fatigue, spoils patients'quality of life. Known as a prognostic factor for several cancers, anemia also lowers radiotherapy or chemotherapy efficiency by tumor hypoxia. Recombinant EPO restores normal haemoglobin level, quality of life and treatment efficiency.
Auclerc
Gérard
G
Service d'oncologie médicale, Hôpital de La-Salpêtrière, 47, bd de l'Hôpital, 75013 Paris. gerard.auclerc@psl-ap-hop-paris.fr
Meric
Jean-Baptiste
JB
Pommeyrol
Arlette
A
Rixe
Olivier
O
Khayat
David
D
D000741:Anemia, Aplastic / Q000209:etiology* / Q000628:therapy; D015687:Cell Hypoxia; D004921:Erythropoietin / Q000172:deficiency; D005221:Fatigue / Q000209:etiology; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D010101:Oxygen Consumption; D011788:Quality of Life; D002583:Uterine Cervical Neoplasms / Q000097:blood / Q000150:complications
D004921:Erythropoietin