title: Nutritional value of a rice-hydrolysate formula in infants with cows' milk protein allergy: a randomized pilot study.
abstract: This study was designed to assess whether a rice-hydrolysate formula allows normal growth and adequate metabolic balance in infants with cows' milk protein allergy. Infants (seven females, nine males; aged 6-14 months) were randomly assigned to receive a rice-hydrolysate formula (n = 8) or a soy formula (control group, n = 8). Standardized growth indices (Z scores) and biochemical parameters were evaluated during a 6-month treatment period. Infants in both groups showed normal growth patterns during the study, and no adverse reactions were seen. Mean plasma biochemical parameters were within the normal ranges, and did not differ between groups. In conclusion, rice-hydrolysate formula may be a nutritionally suitable alternative for infants with cows' milk protein allergy. Larger studies, with satisfactory power, should be undertaken to confirm these findings.
authors.affiliation: Department of Paediatrics, San Paolo Hospital, University of Milan, Milan, Italy. clinped@mailserver.unimi.it
authors.forename: E
authors.initials: E
authors.lastname: D'Auria
authors.forename: M
authors.initials: M
authors.lastname: Sala
authors.forename: F
authors.initials: F
authors.lastname: Lodi
authors.forename: G
authors.initials: G
authors.lastname: Radaelli
authors.forename: E
authors.initials: E
authors.lastname: Riva
authors.forename: M
authors.initials: M
authors.lastname: Giovannini
mesh_terms: D001827:Body Height; D001835:Body Weight; D002657:Child Development; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000008:administration & dosage*; D007227:Infant Nutritional Physiological Phenomena; D008297:Male; D016269:Milk Hypersensitivity; D012275:Oryza; D010865:Pilot Projects; D011446:Prospective Studies; D011492:Protein Hydrolysates; D030262:Soybean Proteins
chemical_list: D011492:Protein Hydrolysates; D030262:Soybean Proteins