title: Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women.
abstract: OBJECTIVE
  This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test.
  
  
  METHODS
  A historical cohort study of 2459 pregnant women systematically examined for gestational diabetes was performed. Information of oral glucose tolerance test results and clinical outcome were collected from medical records.
  
  
  RESULTS
  The risk of hypertensive complications, cesarean section, induction of labor and macrosomia was significantly increased in both overweight women (body mass index [BMI] 25.0-29.9 kg/m(2)) and obese women (BMI >or= 30.0 kg/m(2)) compared with women who were of normal weight (BMI 18.5-24.9 kg/m(2)). The frequencies of shoulder dystocia, preterm delivery, and infant morbidity other than macrosomia were not significantly associated with maternal BMI.
  
  
  CONCLUSIONS
  Prepregnancy overweight and obesity is associated with adverse pregnancy outcome in glucose-tolerant women.
authors.affiliation: Department of Endocrinology, Odense University Hospital, Odense, Denmark. DorteMJ@dadlnet.dk
authors.forename: Dorte M
authors.initials: DM
authors.lastname: Jensen
authors.forename: Peter
authors.initials: P
authors.lastname: Damm
authors.forename: Bente
authors.initials: B
authors.lastname: Sørensen
authors.forename: Lars
authors.initials: L
authors.lastname: Mølsted-Pedersen
authors.forename: Jes G
authors.initials: JG
authors.lastname: Westergaard
authors.forename: Per
authors.initials: P
authors.lastname: Ovesen
authors.forename: Henning
authors.initials: H
authors.lastname: Beck-Nielsen
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002585:Cesarean Section / Q000706:statistics & numerical data; D015331:Cohort Studies; D003718:Denmark; D016640:Diabetes, Gestational / Q000175:diagnosis; D004420:Dystocia / Q000453:epidemiology; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension / Q000150:complications; D007751:Labor, Induced / Q000706:statistics & numerical data; D009765:Obesity / Q000150:complications*; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D015430:Weight Gain