title: Ganglioneuroblastoma metastatic to the orbit.
abstract: A 10-month-old girl presented with an extensive orbital and cranial metastatic lesion from an adrenal ganglioneuroblastoma. Treatment with chemotherapy alone resulted in complete regression of the tumors with over 7 years of follow-up. Good prognostic indicators included her young age at diagnosis, DNA index of tumor cells of 1.4, and the histologic subtype of neuroblastic tumor. This is the first reported case of ganglioneuroblastoma metastatic to the orbit.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA.
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Johnson
authors.forename: Stuart R
authors.initials: SR
authors.lastname: Toledano
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000473:pathology*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D018305:Ganglioneuroblastoma / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D006801:Humans; D007223:Infant; D009419:Nerve Tissue Proteins / Q000032:analysis; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D012888:Skull Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D009419:Nerve Tissue Proteins