Skew in CG content near the transcription start site in Arabidopsis thaliana.
We have discovered a novel statistical feature of Arabidopsis thaliana genome that remarkably correlates with a position of transcription start site--CG skew peak. We hypothesize that the phenomenon can be explained by the higher mutability of unprotected cytosines.
Tatarinova
Tatiana
T
Ceres, Inc, 3007 Malibu Canyon Road, Malibu, CA 90265, USA.
Brover
Vyacheslav
V
Troukhan
Maxim
M
Alexandrov
Nickolai
N
D017360:Arabidopsis / Q000235:genetics*; D001482:Base Composition; D003596:Cytosine; D004252:DNA Mutational Analysis; D014644:Genetic Variation; D018745:Genome, Plant; D006147:Guanine; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D024363:Transcription Initiation Site; D014158:Transcription, Genetic / Q000235:genetics*
D006147:Guanine; D003596:Cytosine