Fluoroquinolone therapy and Achilles tendon rupture.
Fluoroquinolones have been associated with tendinopathies. The authors present three cases of Achilles tendinopathy in which the patients' symptoms were preceded by treatment for unrelated bacterial infections with ciprofloxacin. Although the exact mechanism of the relationship is not understood, those who engage in sports or exercise should be advised of the risk of quinolone-induced tendinopathy.
Vanek
Diane
D
California School of Podiatric Medicine, San Francisco, CA, USA.
Saxena
Amol
A
Boggs
John M
JM
D000125:Achilles Tendon / Q000187:drug effects*; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced; D012307:Risk Factors; D012421:Rupture; D013708:Tendon Injuries / Q000139:chemically induced*
D000890:Anti-Infective Agents; D002939:Ciprofloxacin