[Some parameters of lipid metabolism in children and adolescents in relation to nutritional status].
We often observe nutritional disturbances in children and adolescents leading to obesity or cachexy. For evaluating the state of nutrition or the degree of obesity anthropometrics indices are used such as Body Mass Index (BMI). The aim of the study was analysed the concentration of selected indices of lipid metabolism in serum in children and adolescents with relation to BMI.


METHODS
The examined children were divided into 3 groups: BMI between 10-90 percentiles (186 children), BMI>95 percentiles (27 obese children) and BMI <5 percentiles (17 anorectic girls). In all the studied children concentration of triacyloglycerol, total and HDL cholesterol were assayed in the serum. The level of LDL and VLDL cholesterol was determined with an indirect method. The apolipoproteins:apo-AI and apo-B were assayed in obese children and anorectic girls.


RESULTS
No significant relationship between triacyloglycerol, total cholesterol and cholesterol fractions concentrations and BMI, was found in the group of 186 children (BMI between 10-90 percentiles). Significant positive correlation between BMI and cholesterol LDL in obese children (BMI >95 percentiles) was confirmed (r=0.38, p<0.05). No significant relationship between the lipid parameters and BMI was found in the anorectic girls (BMI< 5 percentiles).


CONCLUSIONS
Children with BMI above 95 centile may constitute a group particularly predisposed for early development of atherosclerosis.
Chrzastek-Spruch
Hanna
H
Klinika Patologii Noworodków, Akademia Medyczna, ul. Chodźki 2, 20-092 Lublin, Poland. hanna@dsk.lublin.pl
Pac-Kozuchowska
Elzbieta
E
D000293:Adolescent; D016632:Apolipoprotein A-I / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D001161:Arteriosclerosis / Q000209:etiology; D015992:Body Mass Index; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D009765:Obesity / Q000097:blood*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008055:Lipids; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides