Abdominal aortic aneurysms: elective endovascular repair versus conventional surgery--evaluation with evidence-based medicine techniques.
OBJECTIVE
To use evidence-based techniques to compare elective open surgical repair of abdominal aortic aneurysms with endovascular repair by means of stent placement.


METHODS
A focused clinical question formed the basis of a literature search. Evidence-based criteria were used to appraise and assign a "level of evidence" to retrieved articles. The following data were determined from the best studies: systemic, local, and/or vascular complications; graft failure rates; blood loss; mortality; length of intensive care and/or hospital stay; mid- and long-term outcomes; cost of endovascular repair versus that of surgery; and eligibility for endovascular repair. Absolute risk reductions and/or increases and numbers needed to treat or harm were calculated.


RESULTS
The best current evidence came from 22 studies, which showed that there is slight, if any, difference between mortality rates of endovascular repair and surgery. Hospital and/or intensive care stay is shorter, blood loss less, and systemic complications fewer (numbers needed to treat, two to 12) with endovascular repair. Some authors reported a significant increase in local and/or vascular complications with endovascular repair (numbers needed to harm, two to six). Graft failure is significantly more common with endovascular repair (numbers needed to harm, four), and substantive adjunctive interventions are needed. Endovascular repair is more expensive than surgery.


CONCLUSIONS
Elective endovascular repair has short-term benefits compared with surgery. There is slight, if any, difference in mortality. Endovascular repair costs more than surgery. At follow-up, surgical grafts performed better.
Maher
Michael M
MM
Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Boston,USA.
McNamara
Ann M
AM
MacEneaney
Peter M
PM
Sheehan
Stephen J
SJ
Malone
Dermot E
DE
D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D016063:Blood Loss, Surgical; D019917:Blood Vessel Prosthesis Implantation / Q000191:economics; D017558:Elective Surgical Procedures / Q000191:economics; D019317:Evidence-Based Medicine; D006084:Graft Rejection; D006801:Humans; D007902:Length of Stay; D015607:Stents; D016896:Treatment Outcome