title: Biotypes and antimicrobial susceptibilities of Brucella isolates.
abstract: 41 Brucella strains isolated from blood and cerebrospinal fluid cultures were identified to species level and biotypes detected. All of the isolates were Brucella melitensis: 2 strains of B. melitensis biotype-1 and 39 strains of B. melitensis biotype-3. In vitro activities of these strains were detected by the E test method. According to the 90% minimal inhibitory concentration (MIC90) values, the most active agent was doxycycline (MIC90 0.064 microg/ml), followed by ciprofloxacin (MIC90 0.25 microg/ml), trimethoprim-sulfamethoxazole and ceftriaxone (MIC90 0.38 microg/ml). Rifampin exhibited the highest MIC90 value (0.75 microg/ml).
authors.affiliation: Infectious Diseases and Clinical Microbiology Clinic, Ankara Numune Training and Research Hospital, Ankara, Turkey. hbodur2@ttnet.net.tr
authors.forename: Hürrem
authors.initials: H
authors.lastname: Bodur
authors.forename: Neriman
authors.initials: N
authors.lastname: Balaban
authors.forename: Sebahat
authors.initials: S
authors.lastname: Aksaray
authors.forename: Vedat
authors.initials: V
authors.lastname: Yetener
authors.forename: Esragül
authors.initials: E
authors.lastname: Akinci
authors.forename: Aylin
authors.initials: A
authors.lastname: Colpan
authors.forename: Ayse
authors.initials: A
authors.lastname: Erbay
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D017347:Brucella melitensis / Q000145:classification* / Q000187:drug effects*; D002006:Brucellosis / Q000175:diagnosis / Q000188:drug therapy*; D002443:Ceftriaxone / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D004318:Doxycycline / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D012293:Rifampin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D004318:Doxycycline; D012293:Rifampin