title: Fulminant liver disease.
abstract: Fulminant liver disease, acute liver failure (ALF), is one of the most intriguing and challenging conditions in the entire field of internal medicine. ALF is defined as the onset of hepatic encephalopathy and coagulopathy in patients with no known underlying liver disease within 8 to 26 weeks of onset of illness. Many cases develop within a few days, dramatically transforming an otherwise healthy individual to a patient with a high risk for developing multi-organ failure and death.
authors.affiliation: Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
authors.forename: Frank Vinholt
authors.initials: FV
authors.lastname: Schiødt
authors.forename: William M
authors.initials: WM
authors.lastname: Lee
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects; D000818:Animals; D006525:Hepatitis, Viral, Human / Q000150:complications; D006801:Humans; D017114:Liver Failure, Acute / Q000139:chemically induced / Q000209:etiology* / Q000628:therapy / Q000821:virology; D011379:Prognosis
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen