Synthetic and antibacterial studies on some new furanopeptides.
A series of new furanopeptides (3) are prepared by the coupling of arylsubstituted furoic acids (1) with amino acid methyl esters, di and tetra-peptide methyl esters using dicyclohexyl carbodiimide (DCC) as coupling agent. Some of the newly synthesized compounds are characterized on the basis of IR, 1H NMR, mass spectral data and elemental analysis. Some of the selected compounds are also tested for their antibacterial properties.
Poojary
Boja
B
Department of Post-Graduate Studies and Research in Chemistry, Mangalore University, Mangalagangothri 574199, India. bojapoojary@yahoo.com
Belagali
S L
SL
Kumar
K Harish
KH
Holla
B Shivarama
BS
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects; D005663:Furans / Q000737:chemistry* / Q000494:pharmacology*; D013058:Mass Spectrometry / Q000379:methods; D019906:Nuclear Magnetic Resonance, Biomolecular; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
D000890:Anti-Infective Agents; D005663:Furans; D009842:Oligopeptides