title: The emergence of a synthetic theory of intron evolution.
abstract: The debate on the origin and evolution of the intron/exon structure of eukaryotic genes has witnessed profound changes in the last 10 years. Concepts from both the introns-early and introns-late theories have merged into a new synthetic theory of intron evolution. Here I review the debate and discuss the perspectives for the future.
authors.affiliation: Ludwig Institute for Cancer Research, Sao Paulo Branch, Rua Prof. Antonio Prudente 109, 4 Andar, 01509-01 Sao Paulo, Brazil. sandro@compbio.ludwig.org.br
authors.forename: Sandro J
authors.initials: SJ
authors.lastname: de Souza
mesh_terms: D019143:Evolution, Molecular; D007438:Introns / Q000235:genetics*