[Seasonal variations in 25-hydroxyvitamin D in young and elderly and populations in Buenos Aires City].
The purpose of this study was to evaluate the level of hypovitaminosis D in elderly and young outpatients populations of the City of Buenos Aires, and to establish its impact on bone remodeling. A total of 83 elderly and 76 young patients aged 71.9 +/- 8.1 and 29.8 +/- 6.6 years respectively, were evaluated by measuring 25-hydroxyvitamin D, 25 (OH)D, middle-molecular parathyroid hormone, and biochemical measurements of bone and mineral metabolism markers. In winter, insufficient values of 25(OH)D were observed both in elderly and young populations: 14.2% of the elderly and 15.9% of young people showed deficient values of 25(OH)D. In summer, an increase in the two groups was observed. Parathyroid hormone levels were higher in the elderly group. Secondary hyperparathyroidism was reported only in the aged group (28.1% in winter, and 20.5% in summer). The increased levels of parathyroid hormone and the presence of secondary hyperparathyroidism in the elderly would be conditioned by this deficiency and other additional factors such as age, renal insufficiency and nutrition degree. In winter, there was an increase in the bone remodeling markers, with higher values in the elderly group. In the City of Buenos Aires decreased levels of 25(OH)D were seen both in young and elderly individuals, with seasonal variations. Sanitary policies are necessary to prevent hypovitaminosis D, because this condition predisposes for osteoporosis.
Fassi
Juliana
J
Servicio de Endocrinología, Metabolismo y Medicina Nuclear, Hospital Italiano de Buenos Aires.
Russo Picasso
María F
MF
Furci
Aída
A
Sorroche
Patricia
P
Jáuregui
Ricardo
R
Plantalech
Luisa
L
D000328:Adult; D000367:Age Factors; D000368:Aged; D001118:Argentina; D015415:Biomarkers / Q000097:blood; D016723:Bone Remodeling; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D012621:Seasons; D014505:Urban Population; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood* / Q000150:complications
D015415:Biomarkers; D010281:Parathyroid Hormone; D014807:Vitamin D; C104450:25-hydroxyvitamin D; D002118:Calcium