title: Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation.
abstract: Zinc is a common supplement and is widely available as a standard component of many over-the-counter products. A number of reports have identified an association between excessive zinc intake and severe cytopenia. We report a case of zinc-induced copper deficiency in a young adult to illustrate this under-recognized cause of anemia and neutropenia.
authors.affiliation: Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia and the University of British Columbia, Vancouver, BC.
authors.forename: Julie A
authors.initials: JA
authors.lastname: Irving
authors.forename: Andre
authors.initials: A
authors.lastname: Mattman
authors.forename: Gillian
authors.initials: G
authors.lastname: Lockitch
authors.forename: Kevin
authors.initials: K
authors.lastname: Farrell
authors.forename: Louis D
authors.initials: LD
authors.lastname: Wadsworth
mesh_terms: D000328:Adult; D000756:Anemia, Sideroblastic / Q000139:chemically induced*; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009503:Neutropenia / Q000139:chemically induced*; D004366:Nonprescription Drugs; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000188:drug therapy; D015032:Zinc / Q000009:adverse effects*
chemical_list: D004366:Nonprescription Drugs; D015032:Zinc