title: Treating coagulopathy in trauma patients.
abstract: Coagulopathy in patients with severe trauma is related to platelet and coagulation factor loss, consumption, and dysfunction. It is exacerbated by dilution, acidosis, and hypothermia. Hemorrhage control, warming, and appropriate blood product support are lifesaving. Further improvements in hemorrhage control will save additional lives and resources.
authors.affiliation: Department of Pathology, University of Maryland Medical Center, Baltimore, MD 21201, USA.
authors.forename: Ray
authors.initials: R
authors.lastname: Armand
authors.forename: John R
authors.initials: JR
authors.lastname: Hess
mesh_terms: D000138:Acidosis; D001779:Blood Coagulation Factors / Q000627:therapeutic use; D001803:Blood Transfusion; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006438:Hemodilution; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007035:Hypothermia; D007668:Kidney / Q000293:injuries; D008099:Liver / Q000293:injuries; D014947:Wounds and Injuries / Q000150:complications*
chemical_list: D001779:Blood Coagulation Factors