title: Delayed manifestation of spinal metastasis: a special feature of hemangiopericytoma.
abstract: Metastatic hemangiopericytoma to the spine is rare, and operative management of these highly vascularized tumors is challenging. Review of the literature identified only seven previously reported cases. Metastases of hemangiopericytomas to the spine are diagnosed often only after a long delay following resection of the primary tumors. To emphasize the clinical and histopathological features of metastatic hemangiopericytoma to the spine and to review treatment options, a case of a delayed metastatic hemangiopericytoma to the cervicothoracic spine is reported: a 48-year-old woman presented with a large metastatic hemangiopericytoma to the cervicothoracic spine causing left-sided cervicobrachialgias and gait disturbance. Magnetic resonance imaging studies revealed a large left-sided dumbbell-shaped intraspinal and extraspinal tumor from C6 to T2. The patient underwent two-staged total removal of the cervicothoracic mass with posterior stabilization and subsequent radiotherapy. Histopathological findings revealed a malignant hemangiopericytoma which had identical features to the primary cranial meningeal tumor removed 8 years earlier. The radicular symptoms and the gait ataxia disappeared, postoperatively. One year later, however, new metastases were present. Patients with hemangiopericytoma should be controlled regularly for local recurrence and systemic tumor spread. The best available treatment for delayed metastasis to the spinal column is complete tumor removal followed by postoperative radiotherapy.
authors.affiliation: Department of Neurosurgery, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. joachim.krauss@nch.ma.uni-heidelberg.de
authors.forename: Johannes
authors.initials: J
authors.lastname: Woitzik
authors.forename: Clemens
authors.initials: C
authors.lastname: Sommer
authors.forename: Joachim K
authors.initials: JK
authors.lastname: Krauss
mesh_terms: D020968:Brachial Plexus Neuritis / Q000209:etiology; D002574:Cervical Vertebrae; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006393:Hemangiopericytoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000150:complications / Q000556:secondary* / Q000601:surgery; D013904:Thoracic Vertebrae; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome