Pattern recognition molecules and innate immunity to parasites.
Recent pioneering advances in understanding how plants, insects and worms eliminate pathogens has led to the realization that innate immunity plays a vital role in protecting humans from infection. This comprehensive review examines the molecules involved in innate immune responses, how they act to control parasites and if their engagement can explain many immune features characteristic of parasitic infections.
McGuinness
David H
DH
Department of Molecular & Cellular Pathology, University of Dundee Medical School, Ninewells Hospital, DD1 9SY, Dundee, UK.
Dehal
Prabhjyot K
PK
Pleass
Richard J
RJ
D000818:Animals; D006790:Host-Parasite Interactions; D006801:Humans; D007113:Immunity, Innate; D008562:Membrane Glycoproteins / Q000502:physiology; D010271:Parasites / Q000276:immunology*; D010272:Parasitic Diseases / Q000276:immunology* / Q000469:parasitology; D010586:Phagocytes / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D051193:Toll-Like Receptors
D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D051193:Toll-Like Receptors