Neuroprotection or neurotoxicity: impact of discontinuous dose-response curves on risk assessment.
Slikker
William
W
Division of Neurotoxicology, National Center for Toxicological Research/FDA, Jefferson, Arkansas 72079, USA.
Duhart
Helen
H
Gaylor
David
D
Imam
Syed
S
D000818:Animals; D017209:Apoptosis; D003042:Cocaine / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D009336:Necrosis; D018696:Neuroprotective Agents / Q000008:administration & dosage*; D016716:PC12 Cells; D051381:Rats; D018570:Risk Assessment
D018696:Neuroprotective Agents; D003042:Cocaine