title: Substrate-controlled highly diastereoselective synthesis of primary and secondary diorganozinc reagents by hydroboration/boron-zinc exchange sequence.
abstract: The scope of substrate-controlled diastereoselective hydroborations can be considerably enhanced by a boron-zinc exchange reaction, providing organozinc derivatives that react with a broad range of electrophiles. Even normally unreactive boronic esters, obtained by Rh-catalyzed hydroboration with catecholborane, react readily with iPr2Zn providing the corresponding zinc reagents in high diastereoselectivity.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität, Munich, Germany.
authors.forename: Eike
authors.initials: E
authors.lastname: Hupe
authors.forename: M Isabel
authors.initials: MI
authors.lastname: Calaza
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel