[Viral hepatitis A as a triggering agent of autoimmune hepatitis report of a case and review of literature].
The case of a 61-year-old woman who developed a picture of viral Hepatitis A with an uncomplicated clinical course is reported herein. However, nine months after the diagnosis, the aminotransferases still remained discretely elevated (AST 78 UI/L, ALT 95 UI/L). At that moment, the patient started to present transient arthralgias and markers were requested for autoimmune hepatitis, which turned out positive, besides presenting hypergammaglobulinemia. A liver biopsy was performed showing changes consistent with mild autoimmune hepatitis. It was considered that the case did not warrant treatment with corticosteroids or immunosuppresants and continued to observe the patient, who is asymptomatic until the publishing of this report. To our knowledge, this is the first report in our country of autoimmune hepatitis triggered by a viral Hepatitis A. The case is reported and the literature is being reviewed.
Tagle Arrospide
Martín
M
Universidad Peruana Cayetano Heredia, Peru.
León Barúa
Raúl
R
D001323:Autoantibodies / Q000097:blood; D005260:Female; D006506:Hepatitis A / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D019693:Hepatitis, Autoimmune / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D008111:Liver Function Tests; D008875:Middle Aged
D001323:Autoantibodies