title: [Catamenial epilepsy].
abstract: Many women with epilepsy report changes in seizures frequency in relationship to their menstrual cycle. Evidence from animal experiments and studies in humans have demonstrated an ovarian steroid hormone effect on neuronal excitability. The entity of the problem and its treatment have yet to be systematically evaluated. Is important to clarify the etiology and pathogenesis of catamenial fluctuations in seizure frequency and to outline optimal management strategies.
authors.affiliation: Cattedra di Ginecologia e Ostetricia, I Istituto di Clinica Ostetrica e Ginecologica, Università degli Studi di Roma La Sapienza, Roma, Italia.
authors.forename: M
authors.initials: M
authors.lastname: Salvi
authors.forename: I
authors.initials: I
authors.lastname: Canova
authors.forename: S
authors.initials: S
authors.lastname: Caputo
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000517:prevention & control; D000818:Animals; D000927:Anticonvulsants / Q000493:pharmacokinetics / Q000627:therapeutic use; D001711:Biotransformation / Q000502:physiology; D000075202:Contraindications; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology / Q000627:therapeutic use; D006727:Hormone Antagonists / Q000627:therapeutic use; D006801:Humans; D008597:Menstrual Cycle; D010060:Ovulation; D011247:Pregnancy; D011293:Premenstrual Syndrome / Q000150:complications / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants; D012739:Gonadal Steroid Hormones; D006727:Hormone Antagonists