title: Hzf-3 expression in the amygdala after establishment of conditioned taste aversion.
abstract: We studied the regulation of the expression of the inducible orphan nuclear receptor known as HZF-3 (or Nurr1) in acquisition of conditioned taste aversion in rats. Our results show that HZF-3 expression in the lateral/basolateral (LA/BLA) amygdala complex was significantly up-regulated when both the conditioned and the unconditioned stimuli were paired, but not when either of the stimuli was presented alone. Induction in the LA/BLA had a faster onset than induction in the central nucleus of the amygdala. The results implicate HZF-3 in the acquisition of associative aversive experiences.
authors.affiliation: Department of Biology, University of Puerto Rico, Río Piedras Campus, Gándara Avenue, Julio García Díaz Building, Room 108, PO Box 23360, San Juan, Puerto Rico, USA.
authors.forename: H
authors.initials: H
authors.lastname: Ge
authors.forename: R
authors.initials: R
authors.lastname: Chiesa
authors.forename: S
authors.initials: S
authors.lastname: Peña de Ortiz
mesh_terms: D000679:Amygdala / Q000378:metabolism*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D003213:Conditioning, Psychological / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000096:biosynthesis* / Q000235:genetics; D005786:Gene Expression Regulation / Q000502:physiology; D008297:Male; D057126:Nuclear Receptor Subfamily 4, Group A, Member 2; D051381:Rats; D020318:Rats, Long-Evans; D013649:Taste / Q000502:physiology*; D014157:Transcription Factors / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D004268:DNA-Binding Proteins; C539884:Nr4a2 protein, rat; D057126:Nuclear Receptor Subfamily 4, Group A, Member 2; D014157:Transcription Factors