[Anti-tumor effect of polysaccharide from Grifola frondosa and its influence on immunological function].
When the polysaccharide from Grifola frondosa (PGF) was taken orally by S180 bearing mice at the dosage of 50-150 mg/kg.d for 9 d, the inhibitory rate to S180 was 27.97%-38.46%. The PGF can also enhance thymus index, the ability of splenic lymphocyte proliferation and formation of antibody in splenic cells, and promote the production of IgM hemolysin significantly in S-180 bearing mice.
Li
Xiaoding
X
Department of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070.
Rong
Jianhua
J
Wu
Moucheng
M
Zeng
Xiaobo
X
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000363:Agaricales / Q000737:chemistry*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006460:Hemolysin Proteins / Q000097:blood; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000188:drug therapy / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D006460:Hemolysin Proteins; D011134:Polysaccharides