Serologic evidence of infection with ehrlichiae and spotted fever group rickettsiae among residents of Gag Island, Indonesia.
The causative agents of scrub and murine typhus are considered endemic to Indonesia. However, the presence of spotted fever group rickettsiae and ehrlichiae have not been previously described in this country. During an investigation of arthropod-borne diseases on Gag Island, located northwest of the island of New Guinea in eastern Indonesia, the prevalence of antibody to the etiologic agents of monocytic ehrlichiosis, spotted fever rickettsiosis, and scrub and murine typhus were determined. Analysis of 55 blood samples from residents of Gag Island showed seroreactivity to antigen preparations of Ehrlichia chaffeensis (7 of 48, 14.6%), two spotted fever group rickettsiae: Rickettsia rickettsii (5 of 48, 10.4%) and R. conorii (10 of 49, 20.4%), Orientia tsutsugamushi (5 of 53, 9.4%), and R. typhi (1 of 48, 2.1% [by an indirect immunofluorescence assay] and 1 of 50, 2.0% [by an enzyme-linked immunosorbent assay]). These results show serologic evidence of infection with ehrlichiae and spotted fever group rickettsiae for the first time in Indonesia in a location where the prevalence of antibody to O. tsutsugamushi and R. typhi was lower.
Richards
Allen L
AL
U.S. Naval Medical Research Unit No. 2, Jakarta, Indonesia. RichardsA@nmrc.navy.mil
Ratiwayanto
Sutanti
S
Rahardjo
Eko
E
Kelly
Daryl J
DJ
Dasch
Gregory A
GA
Fryauff
David J
DJ
Bangs
Michael J
MJ
D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000276:immunology; D018469:Ehrlichia chaffeensis / Q000276:immunology*; D016873:Ehrlichiosis / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D012285:Orientia tsutsugamushi / Q000276:immunology; D020114:Rickettsia conorii / Q000276:immunology; D012284:Rickettsia rickettsii / Q000276:immunology; D012286:Rickettsia typhi / Q000276:immunology; D012288:Rickettsiaceae Infections / Q000453:epidemiology*; D016996:Rickettsieae / Q000276:immunology*; D016036:Seroepidemiologic Studies
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial