[Clinical study on "sini" decoction in treating stenocardia for coronary heart disease].
OBJECTIVE
To observe clinical effect of "Sini" decoction on stenocardia for coronary heart disease.


METHODS
63 cases of stenocardia for coronary heart disease with deficiency of yang or cold syndrome were randomly divided into "Sini" decoction group (therapeutic group, 35 cases) and isosorbide dinitrate group (contrast group, 28 cases). Drug effects of the two groups were compared by clinical symptoms, electrocardiogram (ECG), myocardial oxygen consumption and cardiac function.


RESULTS
Similar to isosorbide dinitrate, "Sini" decoction could improve clinical symptoms and ECG, decrease frequency of stenocardia and dose of nitroglycerin on stenocardia for coronary heart disease. But "Sini" decoction had better effects on reducing myocardial oxygen consumption and improving cardiac funrtion than isosorbide dinitrate.


CONCLUSIONS
"Sini" decoction can treat stenocardia for coronary heart disease with deficiency of yang or cold syndrome.
Jin
Minghua
M
First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080.
Qin
Jian
J
Wu
Weikang
W
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004562:Electrocardiography; D005260:Female; D006334:Heart Function Tests; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry*; D014665:Vasodilator Agents / Q000627:therapeutic use*; D016711:Yang Deficiency / Q000188:drug therapy / Q000503:physiopathology
D004365:Drugs, Chinese Herbal; D014665:Vasodilator Agents; C478756:sini tang; D007548:Isosorbide Dinitrate