Exploration of the biomimetic synthesis of indole-diterpene mycotoxins: an unexpected cascade reaction during the attempted synthesis of emindole SB.
The key step in an attempted biomimetic synthesis of the indole-diterpene mycotoxin emindole SB delivers the pentacyclic compound resulting from 6-endo cyclisation instead of the product arising by the 5-exo reaction required in the putative biosynthetic pathway.
Clark
J Stephen
JS
School of Chemistry, University of Nottingham, University Park, Nottingham, UK NG7 2RD. j.s.clark@nottingham.ac.uk
Myatt
James
J
Wilson
Claire
C
Roberts
Lee
L
Walshe
Nigel
N
D032701:Biomimetics / Q000379:methods*; D004224:Diterpenes / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis*; D009183:Mycotoxins / Q000138:chemical synthesis*
D004224:Diterpenes; D007211:Indoles; D009183:Mycotoxins; C030374:indole