title: [Lactose tolerance in children with chronic gastroduodenal zone diseases].
abstract: We determined the dependence of the frequency of lactose intolerance, particular features of the clinical presentation and laboratory showings on lactase deficiency on the basis of a complex clinical, anamnestic and laboratory study of 149 children with chronic gastroduodenal pathologies. It was established that the prevalence of lactose intolerance in children with superficial gastroduodenitis amounts to 58.8%, in children with erosive gastroduodenitis--66.7% and in children with stomach ulcers--83.3%. During the oral lactose load and a subsequent laboratory study we revealed an impairment of the hydrolytic function of small intestines accompanied by an increase of fecal excretion of carbohydrates (lactose and monosaccharides) as well as a considerable enhancement of bacterial fermentation. The detection of fecal excretion of the total glycoprotein hexoses characterizes a disorder of the morphofunctional state of the gastrointestinal tract in children with intestinal enzymopathies.
authors.affiliation: Stavropol State Medical Academy.
authors.forename: L Ia
authors.initials: LIa
authors.lastname: Klimov
mesh_terms: D000222:Adaptation, Physiological; D000293:Adolescent; D002648:Child; D004378:Duodenal Diseases / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007785:Lactose / Q000008:administration & dosage*; D007787:Lactose Intolerance / Q000503:physiopathology; D008297:Male; D013272:Stomach Diseases / Q000503:physiopathology*
chemical_list: D007785:Lactose