title: Continuous flow reactors for drug discovery.
abstract: To develop a new generation of drugs, pharmaceutical companies need to be able to synthesize and screen novel chemicals with enhanced speed. New technology that would enable a cost-neutral increase in the number of potential drug candidates would provide a distinct competitive advantage. The miniaturisation of chemical reactors offers many fundamental and practical advantages of relevance to the pharmaceutical industry, which is constantly searching for controllable, information-rich, high-throughput and environmentally friendly methods of producing compounds with a high degree of chemical selectivity. This article reviews the current and future applications of micro reactors that could enhance the drug discovery process.
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, Hull, UK HU6 7RX. P.Watts@hull.ac.uk
authors.forename: Paul
authors.initials: P
authors.lastname: Watts
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Haswell
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000639:trends*; D015195:Drug Design; D004345:Drug Industry; D023281:Genomics; D010455:Peptides / Q000138:chemical synthesis; D013329:Structure-Activity Relationship; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000639:trends
chemical_list: D010455:Peptides