title: Kinematic and deformation analysis of 4-D coronary arterial trees reconstructed from cine angiograms.
abstract: In the cardiovascular arena, percutaneous catheter-based interventional (i.e., therapeutic) procedures include a variety of coronary and other vascular system interventions. These procedures use two-dimensional (2-D) X-ray-based imaging as the sole or the major imaging modality for procedure guidance and quantification of key parameters. Coronary vascular curvilinearity is one key parameter that requires a four-dimensional (4-D) format, i.e., three-dimensional (3-D) anatomical representation that changes during the cardiac cycle. A new method has been developed for reconstruction and analysis of these patient-specific 4-D datasets utilizing routine cine angiograms. The proposed method consists of three major processes: 1) reconstruction of moving coronary arterial tree throughout the cardiac cycle; 2) establishment of temporal correspondence with smoothness constraints; and 3) kinematic and deformation analysis of the reconstructed 3-D moving coronary arterial trees throughout the cardiac cycle.
authors.affiliation: Division of Cardiology, B-132, Department of Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Ave., Denver, CO 80262, USA. James.Chen@uchsc.edu
authors.forename: S Y James
authors.initials: SY
authors.lastname: Chen
authors.forename: John D
authors.initials: JD
authors.lastname: Carroll
mesh_terms: D000465:Algorithms; D019412:Anatomy, Cross-Sectional / Q000379:methods*; D002932:Cineangiography / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods*; D004548:Elasticity; D006801:Humans; D009038:Motion; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*