Fenretinide as an anti-angiogenic agent in neuroblastoma.
Angiogenesis is a critical event in the progression of human neuroblastoma. This mini-review summarizes our literature and experimental data concerning the use of anti-angiogenic molecules, such as TNP-470 and fenretinide, in neuroblastoma treatment.
Ribatti
Domenico
D
Department of Human Anatomy and Histology, University of Bari Medical School, Policlinico, 11 I-70124 Bari, Italy. ribatti@anatomia.uniba.it
Raffaghello
Lizzia
L
Marimpietri
Danilo
D
Cosimo
Emilio
E
Montaldo
P Giuseppe
PG
Nico
Beatrice
B
Vacca
Angelo
A
Ponzoni
Mirco
M
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017313:Fenretinide / Q000627:therapeutic use*; D006801:Humans; D009389:Neovascularization, Pathologic / Q000517:prevention & control*; D009447:Neuroblastoma / Q000098:blood supply* / Q000188:drug therapy
D020533:Angiogenesis Inhibitors; D000970:Antineoplastic Agents; D017313:Fenretinide