title: Blackgram fiber (Phaseolus mungo): mechanism of hypoglycemic action.
abstract: The effect of the administration of blackgram fiber (Phaseolus mungo) on the metabolism of carbohydrates was studied in rats fed 30% NDF (neutral detergent fiber) diet. The experimental group showed a significant increase in liver glycogen level and a significant decrease in blood glucose. Significant increases in the activities of glycogen phosphorylase, hexokinase, fructose-1, 6-diphosphatase, glucose-6-phosphate dehydrogenase and isocitrate dehydrogenase were observed in the experimental group. The activities of phosphoglucomutase and glucose-6-phosphatase were significantly lower in rats fed the fiber diet. The study showed that blackgram fiber exhibits significant hypoglycemic action in experimental animals.
authors.affiliation: Department of Biochemistry, University of Kerala, Kariavattom Thiruvananthapuram - 695 581, India.
authors.forename: R G
authors.initials: RG
authors.lastname: Boby
authors.forename: S
authors.initials: S
authors.lastname: Leelamma
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D003902:Detergents; D004043:Dietary Fiber / Q000008:administration & dosage / Q000378:metabolism*; D038321:Glycemic Index; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008112:Liver Glycogen / Q000032:analysis; D008297:Male; D027805:Phaseolus / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D001786:Blood Glucose; D003902:Detergents; D004043:Dietary Fiber; D007004:Hypoglycemic Agents; D008112:Liver Glycogen