title: A case of hepatic inflammatory pseudotumor with primary biliary cirrhosis.
abstract: Inflammatory pseudotumor (IPT) of the liver is an unusual non-neoplastic benign lesion. A 75-year-old man was hospitalized for esophageal varices and gastric cancer. Three years before admission, he had been diagnosed as having primary biliary cirrhosis (PBC) without Sjögren's syndrome. Computed tomography (CT) and magnetic resonance imaging (MRI) scans showed multiple masses (S3, S5, S6) less than 2 cm in diameter in the liver. Since these masses were difficult to distinguish from hepatocellular carcinoma, or metastatic liver carcinoma, one of the masses (S5) was removed during an operation for gastric cancer. Histological examination demonstrated marked infiltration of plasma cells and some histiocytes, findings consistent with the histological features of IPT. The coexistence of hepatic IPT and PBC in this case may have been an accidental event. However, the immunological and environmental factors associated with PBC are thought to be involved in the development of IPT; in addition, cholangitis associated with PBC could have contributed to the development of IPT.
authors.affiliation: Department of Internal Medicine II, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, 960-1295, Fukushima, Japan
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Rai
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
authors.forename: Jun
authors.initials: J
authors.lastname: Tojo
authors.forename: Junko
authors.initials: J
authors.lastname: Takiguchi
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Shishido
authors.forename: Yukio
authors.initials: Y
authors.lastname: Sato
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nozawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Masuda