title: A new triterpene from Leandra chaetodon.
abstract: A new triterpene compound ( 1), along with arjunolic acid, was isolated from an ethanol extract of the whole plant of Leandra chaetodon. Based on spectroscopic analysis, the structure of 1 was determined as 2alpha,6alpha- dihydroxybetulinic acid. Arjunolic acid showed inhibitory activity against Cryptococcus neoformans. (IC50 = 20 micrograms/mL).
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, Thad Cochran Research Center, School of Pharmacy, The University of Mississippi, University, MS, USA.
authors.forename: Qinglin
authors.initials: Q
authors.lastname: Zhang
authors.forename: Hala N
authors.initials: HN
authors.lastname: ElSohly
authors.forename: Xing-Cong
authors.initials: XC
authors.lastname: Li
authors.forename: Larry A
authors.initials: LA
authors.lastname: Walker
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D003455:Cryptococcus neoformans / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D027822:Myrtaceae; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D014315:Triterpenes / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D014315:Triterpenes