Is survival possible without arachidonate metabolites in the brain during systemic infection?
The central nervous system mediates a coordinated set of biological responses during systemic immune stimuli. These responses are essential for the organism to eliminate invading pathogens and restore health. Coincidentally, centrally produced prostaglandins play a determinant role in activating the neuronal circuits involved in the control of autonomic functions.
Zhang
Ji
J
Laboratory of Molecular Endocrinology, Centre de Recherche de l'Université Laval and Department of Anatomy and Physiology, Laval University, Québec City, Québec, Canada G1V 4G2.
Rivest
Serge
S
D016718:Arachidonic Acid / Q000378:metabolism*; D001921:Brain / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007239:Infections / Q000276:immunology* / Q000378:metabolism*
D016718:Arachidonic Acid