title: Using a castor oil-balsam of Peru-trypsin ointment to assist in healing skin graft donor sites.
abstract: Skin graft donor sites are partial-thickness wounds that are commonly managed with gauze-type dressings. As such, they often cause more pain and difficulty in healing than the graft-recipient site. A retrospective study was conducted to ascertain the effects of using a castor oil-balsam of Peru-trypsin containing ointment on skin graft donor sites in 36 consecutive patients (16 female, 20 male). All donor sites were epithelialized after 11 days (range 6 to 11 days, mean 8 days) and no wound complications were observed. Given these healing results and product ease of use, this particular formulation has become the facilities' current treatment of choice and further study is indicated and warranted.
authors.affiliation: Fountain Valley Regional Hospital Wound Care Program, Fountain Valley, CA 92708, USA. sncarson@yahoo.com
authors.forename: Stanley N
authors.initials: SN
authors.lastname: Carson
authors.forename: Christopher
authors.initials: C
authors.lastname: Wiggins
authors.forename: Karen
authors.initials: K
authors.lastname: Overall
authors.forename: Jackie
authors.initials: J
authors.lastname: Herbert
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001453:Balsams / Q000494:pharmacology / Q000627:therapeutic use*; D001458:Bandages; D002368:Castor Oil / Q000494:pharmacology / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011182:Postoperative Care / Q000379:methods; D012189:Retrospective Studies; D017592:Skin Care / Q000379:methods*; D016038:Skin Transplantation / Q000009:adverse effects; D016896:Treatment Outcome; D014357:Trypsin / Q000494:pharmacology / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D001453:Balsams; D004338:Drug Combinations; D009824:Ointments; D002368:Castor Oil; C025080:Peruvian balsam; D014357:Trypsin