Neurotoxicity of nitrous oxide and ketamine is more severe in aged than in young rat brain.
Beals
J K
JK
Department of Anesthesiology, University of Virginia Health System, Charlottesville 22908, USA.
Carter
L B
LB
Jevtovic-Todorovic
V
V
D000375:Aging / Q000502:physiology*; D000778:Anesthetics, Dissociative / Q000494:pharmacology / Q000633:toxicity*; D018685:Anesthetics, Inhalation / Q000494:pharmacology / Q000633:toxicity*; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D005260:Female; D007649:Ketamine / Q000494:pharmacology / Q000633:toxicity*; D009609:Nitrous Oxide / Q000494:pharmacology / Q000633:toxicity*; D051381:Rats; D011916:Rats, Inbred F344; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors
D000778:Anesthetics, Dissociative; D018685:Anesthetics, Inhalation; D016194:Receptors, N-Methyl-D-Aspartate; D007649:Ketamine; D009609:Nitrous Oxide