[Synthesis, characterization and blood compatibility studies of biomedical aliphatic polyurethanes].
The one-step method was adopted in this study to synthesize aliphatic polyurethane with 4,4-methylene dicyclohexyl diisocyanate(HMDI), 1,4-butanediol (BDO) and poly (tetrahydrofuran) (PTMG). The tests conducted on this material were: FIR spectrum, mechanical properties test, water contact angles test, hemolysis test and platelet adhesion test. Results showed that this material has a good tensile strength up to 30 Mpa, similar to aromaphatic polyurethane. But its tensile elongation, tensile permanent change, hydrophility are better than those of aromaphatic polyurethane. The hemolysis test and platelet adhesion test showed that it has good blood compatibility.
Du
Minhui
M
Department of Polymer, Sichuan University, Chengdu 610065.
Li
Jianshu
J
Wei
Yang
Y
Xie
Xingyi
X
He
Chengsheng
C
Fan
Cuirong
C
Zhong
Yinping
Y
D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D066298:In Vitro Techniques; D008422:Materials Testing; D010973:Platelet Adhesiveness / Q000187:drug effects; D011140:Polyurethanes / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D011817:Rabbits; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013718:Tensile Strength
D001672:Biocompatible Materials; D011140:Polyurethanes