title: [Changes in the indices of lipid metabolism in patients with ischemic heart disease occupied in natural gas fields].
abstract: The influence of adaptation to periodic pressure-chamber hypoxia produced on the condition of the lipid spectrum of blood serum before and after adaptation as well as in 3, 6 and 10 months after hypoxic training was studied in 46 patients with ischemic heart disease working at a enterprise specializing in winning and processing the hydrogen-sulfide-containing gas-condensate. The adaptation therapy was found to result in a reliable reduction of the total cholesterol level, of the level of cholesterol of lipoproteins of the low and extra low densities and of triglycerides; it also contributed to the increase of cholesterol of lipoproteins of the high density in blood serum, which, in the end, ensures a reduced atherogenic coefficient. The positive-for-organism changes in the lipid spectrum of blood serum hold on in patients with coronary heart disease for as long as 6 months after the adaptation therapy. The nature and degree of blood lipids' changes depend on an initial level of the atherogenic index; they were maximally pronounced in persons with the index exceeding 3, and virtually absent in IHD patients with the atherogenicity coefficient being below the mentioned figure.
authors.forename: A N
authors.initials: AN
authors.lastname: Tin'kov
authors.forename: S S
authors.initials: SS
authors.lastname: Makshantsev
authors.forename: A B
authors.initials: AB
authors.lastname: Prokof'ev
authors.forename: S V
authors.initials: SV
authors.lastname: Perepelkin
mesh_terms: D008076:Cholesterol, HDL / Q000097:blood*; D015243:Cholesterol, VLDL / Q000097:blood*; D005579:Fossil Fuels; D006801:Humans; D007221:Industry; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000178:diet therapy; D009784:Occupational Diseases / Q000097:blood*; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D015243:Cholesterol, VLDL; D005579:Fossil Fuels; D014280:Triglycerides