title: Surgical treatment of intracranial epidermoid tumors.
abstract: Intracranial epidermoid tumors are rare, potentially curable, benign lesions that are sometimes associated with perioperative complications, and tend to recur if not completely removed. Histologically benign epidermoid tumors may also develop into highly malignant tumors. This study evaluated on 28 cases of intracranial epidermoid tumor treated over a 13-year period by radical resection with microneurosurgical techniques. The majority of patients underwent computed tomography and/or magnetic resonance imaging within the first 24 hours postoperatively to confirm the results of surgery. Radical surgical resection was achieved in 21 of the 28 cases, and there was no operative mortality. The most common postoperative complication was transient paresis of various cranial nerves. During a mean follow up of 6 years, only one tumor became malignant. Radical surgical resection should be the goal in treating these benign lesions, but if not possible, every effort should be made to minimize the amount of tumor tissue that remains.
authors.affiliation: Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors.forename: Ziya
authors.initials: Z
authors.lastname: Akar
authors.forename: Necmettin
authors.initials: N
authors.lastname: Tanriover
authors.forename: Saffet
authors.initials: S
authors.lastname: Tuzgen
authors.forename: Ali M
authors.initials: AM
authors.lastname: Kafadar
authors.forename: Cengiz
authors.initials: C
authors.lastname: Kuday
mesh_terms: D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000601:surgery*; D004814:Epidermal Cyst / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies