Collagen- versus gelatine-coated Dacron versus stretch PTFE bifurcation grafts for aortoiliac occlusive disease: long-term results of a prospective, randomized multicenter trial.
BACKGROUND
In this prospective randomized multicenter trial, knitted gelatine-coated Dacron, knitted collagen-coated Dacron, and stretch polytetrafluoroethylene (PTFE) aortic bifurcation grafts were compared for their long-term results.


METHODS
Between 1991 and 1998, 149 patients undergoing elective revascularization for aortoiliac occlusive disease were prospectively randomized at 3 tertiary referral centers of vascular surgery. The patients received either gelatine-coated Dacron (GEL-D) grafts (n = 52), collagen-coated Dacron (COL-D) grafts (n = 49), or stretch PTFE grafts (n = 48).


RESULTS
No intraoperative deaths were recorded. The 30-day mortality was 4%. The mean follow-up time was 97 months. Primary patency rates were 77% for GEL-D, 78% for COL-D, and 79% for PTFE at 8 years. The differences were not different (P >.8). Secondary corrected 8-year patency rates were also not significantly different (P >.5): 91% for GEL-D, 96% for COL-Dm and 90% for PTFE. Five Dacron and 1 PTFE grafts were affected by infections.


CONCLUSIONS
Bifurcation grafts for revascularization of aortoiliac occlusive disease using these 3 materials were comparable in terms of primary and secondary patency and long-term complication rates.
Prager
Manfred R
MR
University of Vienna Medical School and the Ludwig Boltzmann Research Institute for Interdisciplinary Vascular Medicine, Vienna, Austria.
Hoblaj
Thomas
T
Nanobashvili
Josif
J
Sporn
Emanuel
E
Polterauer
Peter
P
Wagner
Otto
O
Böhmig
Hans-Jörg
HJ
Teufelsbauer
Harald
H
Ploner
Meinrad
M
Huk
Ihor
I
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D020099:Coated Materials, Biocompatible; D003094:Collagen; D005260:Female; D005500:Follow-Up Studies; D005780:Gelatin; D006801:Humans; D007083:Iliac Artery / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D011446:Prospective Studies; D016459:Prosthesis-Related Infections; D014654:Vascular Patency
D020099:Coated Materials, Biocompatible; D011093:Polyethylene Terephthalates; D005780:Gelatin; D011138:Polytetrafluoroethylene; D003094:Collagen