title: [Anatomical and clinical correlations in the cerebellar eredodegeneration].
abstract: Spinocerebellar hereditary degeneration makes up a heterogeneous group of diseases headed by Strumpell-Lorrain syndrome and Friedreich's disease. They are a heterogeneous group characterized by spasticity and paraplegia and related to demyelinization of the pyramidal tract and of the posterior cordons. During a 4-year period, we studied 14 patients (42-61 years old) suffering cerebellar eredodegeneration (hereditary ataxia). The aim of our work was to correlate anatomopathological findings with clinical signs. The important role played by the cerebellum in vesicosphincterial coordination was shown; in particular severe alteration of the ponto-cerebellar bundles could be cause of the abnormal behaviour of the detrusor.
authors.affiliation: Divisione di Urologia, Azienda Ospedaliera Fatebenefratelli, Milano, Italy.
authors.forename: Umberto
authors.initials: U
authors.lastname: Pea
authors.forename: Francesco
authors.initials: F
authors.lastname: de Luca
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Nicola
authors.forename: Luigi
authors.initials: L
authors.lastname: Galli
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013132:Spinocerebellar Degenerations / Q000473:pathology* / Q000503:physiopathology; D001750:Urinary Bladder, Neurogenic / Q000209:etiology / Q000503:physiopathology