Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action.
Safe
Stephen
S
Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas 77843-4466, USA. ssafe@cvm.tamu.edu
Wormke
Mark
M
D000818:Animals; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D001667:Binding, Competitive; D001943:Breast Neoplasms / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D003546:Cysteine Endopeptidases / Q000378:metabolism; D004268:DNA-Binding Proteins; D004958:Estradiol / Q000008:administration & dosage / Q000378:metabolism; D004965:Estrogen Antagonists / Q000378:metabolism / Q000494:pharmacology*; D047628:Estrogen Receptor alpha; D005260:Female; D005786:Gene Expression Regulation / Q000187:drug effects; D005833:Genital Neoplasms, Female / Q000378:metabolism; D006801:Humans; D009097:Multienzyme Complexes / Q000037:antagonists & inhibitors / Q000378:metabolism; D000072317:Polychlorinated Dibenzodioxins / Q000494:pharmacology* / Q000633:toxicity; D046988:Proteasome Endopeptidase Complex; D020239:Receptor Cross-Talk / Q000187:drug effects*; D018336:Receptors, Aryl Hydrocarbon / Q000819:agonists / Q000235:genetics / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism; D014407:Tumor Cells, Cultured; D014599:Uterus / Q000378:metabolism
C497396:ARNT protein, human; D004268:DNA-Binding Proteins; D004965:Estrogen Antagonists; D047628:Estrogen Receptor alpha; D009097:Multienzyme Complexes; D000072317:Polychlorinated Dibenzodioxins; D018336:Receptors, Aryl Hydrocarbon; D011960:Receptors, Estrogen; D014157:Transcription Factors; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D004958:Estradiol; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex