[Effects of the oxygen partial pressure in inspired gaseous mixture on the functional state of the circulatory, respiratory and erythropoietic systems: a mathematical model].
Oxygen partial pressure in inspired gaseous mixture has a profound effect on the function of the circulatory, respiratory and erythropoietic systems. A mathematical model is proposed to optimize the function of these systems when breathing air with various PO2. The model is based on the principle of minimum energy expenditure. Erythrocyte count, arterial oxygen tension, cardiac output, and pulmonary ventilation are determined as a function of inspired PO2. The model results are in good agreement with the data for permanent altitude residents.
Bukharov
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IB
D001775:Blood Circulation / Q000502:physiology*; D004920:Erythropoiesis / Q000502:physiology*; D006801:Humans; D008962:Models, Theoretical; D010100:Oxygen; D010313:Partial Pressure; D012119:Respiration
D010100:Oxygen