title: Neurotoxicity of nitrous oxide and ketamine is more severe in aged than in young rat brain.
authors.affiliation: Department of Anesthesiology, University of Virginia Health System, Charlottesville 22908, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Beals
authors.forename: L B
authors.initials: LB
authors.lastname: Carter
authors.forename: V
authors.initials: V
authors.lastname: Jevtovic-Todorovic
mesh_terms: D000375:Aging / Q000502:physiology*; D000778:Anesthetics, Dissociative / Q000494:pharmacology / Q000633:toxicity*; D018685:Anesthetics, Inhalation / Q000494:pharmacology / Q000633:toxicity*; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D005260:Female; D007649:Ketamine / Q000494:pharmacology / Q000633:toxicity*; D009609:Nitrous Oxide / Q000494:pharmacology / Q000633:toxicity*; D051381:Rats; D011916:Rats, Inbred F344; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors
chemical_list: D000778:Anesthetics, Dissociative; D018685:Anesthetics, Inhalation; D016194:Receptors, N-Methyl-D-Aspartate; D007649:Ketamine; D009609:Nitrous Oxide