title: Early prediction of seizure remission in children with occipital lobe epilepsy.
abstract: The purpose of this study was to identify early predictors of seizure remission in occipital lobe epilepsy irrespective of syndrome classification i.e. idiopathic or symptomatic occipital lobe epilepsy. Forty-three children with occipital lobe epilepsy had taken part in an earlier study of seizure semiology, neurological deficits, psychomotor/cognitive status, electroencephalography (EEG) and neuroimaging. On the basis of the results of a questionnaire on the state of their epilepsy in 2000, two groups were composed. One group (n=17) consisted of the children with a complete seizure remission of 5 years or more, and the other (n=26) comprised children whose last seizure occurred less than 5 years ago. Our findings indicate that neurological deficit and EEG characteristics can predict 5 year outcome of occipital lobe epilepsy. Neuroradiological abnormality, psychomotor/cognitive status and seizure semiology appear to be of more limited value.
authors.affiliation: Department of Paediatric Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Mennink
authors.forename: Onno
authors.initials: O
authors.lastname: van Nieuwenhuizen
authors.forename: Aag
authors.initials: A
authors.lastname: Jennekens-Schinkel
authors.forename: Yvonne T
authors.initials: YT
authors.lastname: van der Schouw
authors.forename: Wil
authors.initials: W
authors.lastname: van der Meij
authors.forename: Alexander C
authors.initials: AC
authors.lastname: van Huffelen
mesh_terms: D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000150:complications / Q000175:diagnosis; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D011596:Psychomotor Disorders / Q000150:complications / Q000175:diagnosis; D012074:Remission Induction; D012189:Retrospective Studies; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors