Targeting cancer: a NOvel way.
A nitric oxide (NO) prodrug has been shown to selectively kill NO-sensitive leukemia cells, leaving healthy cells unharmed.
Habeck
Martina
M
D000818:Animals; D001391:Azo Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D007938:Leukemia / Q000188:drug therapy*; D051379:Mice; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use*; D014407:Tumor Cells, Cultured
D001391:Azo Compounds; C474958:O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate; D010879:Piperazines