Bone involvement and abcess formation by neutrophil-rich CD30+ anaplastic large-cell lymphoma mimicking skeletal infection in an AIDS patient.
Neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) is a rare pathological entity without distinct clinical behavior. Twelve cases of neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) have been reported, three of them were HIV-infected patients. All these reports stressed the presence of neutrophil infiltration as a new morphologic feature of CD30+ ALCL. Only one case of cutaneous involvement presented with microabscess formation. We describe a case of neutrophil-rich CD30+ ALCL in an AIDS patient with a clinical picture determined by the massive neutrophil infiltration of the tumor without necrosis nor local infection, but with the formation of abscesses.
Mira
José A
JA
Servicio de Medicina Interna, Hospital Universitario de Valme, Carretera de Cádiz s/n, Sevilla, Spain.
Fernández-Alonso
Jorge
J
Macías
Juan
J
Sáez
Carmen
C
Japón
Miguel A
MA
Pereda
Teresa
T
Pineda
Juan A
JA
D000038:Abscess / Q000150:complications*; D000328:Adult; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007085:Ilium; D017730:Ki-1 Antigen / Q000032:analysis*; D016483:Lymphoma, AIDS-Related / Q000150:complications; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000473:pathology*; D008297:Male; D009504:Neutrophils / Q000473:pathology*
D017730:Ki-1 Antigen