title: [Antidepressant effect of ethanol extracts from three species of sect. Hypericum medicinal plants in mice].
abstract: OBJECTIVE
  To explore the antidepressant actions of ethanol extracts from three species of sect. Hypericum medicinal plants.
  
  
  METHODS
  The forced swimming test and mouse tail suspensions in mice were used.
  
  
  RESULTS
  Ethanol extracts of sect. Hypericum medicinal plants significantly shortened motionless time of mice forced swimming and despair time of mouse tail suspension in the two behavior despair animal models of depression. The effect of H. faberi was weaker than that of H. perforatum.
  
  
  CONCLUSIONS
  These findings demonstrated that the extracts from three species of sect. Hypericum medicinal plants possessed obvious antidepressant activity.
authors.affiliation: Chengdu University of Traditional Chinese Medicine, 610075.
authors.forename: Deguan
authors.initials: D
authors.lastname: Wan
authors.forename: Jin
authors.initials: J
authors.lastname: Pei
authors.forename: Mingmei
authors.initials: M
authors.lastname: Zhou
authors.forename: Guangzhi
authors.initials: G
authors.lastname: Wang
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D020902:Hypericum / Q000737:chemistry* / Q000145:classification; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D011597:Psychomotor Performance / Q000187:drug effects; D013045:Species Specificity; D013550:Swimming
chemical_list: D000928:Antidepressive Agents; D004365:Drugs, Chinese Herbal