title: Bilateral hearing loss during vincristine therapy: a case report.
abstract: Vincristine sulfate is a chemotherapeutic agent used in different cancer therapies. It is also the first choice of treatment for peripheral T-cell lymphoma with cyclophosphamide and adriamycin. Sudden hearing loss during vincristine therapy is a very rare event. This is a case of a 16-year old girl who developed sudden bilateral hearing loss related to vincristine therapy.
authors.affiliation: Department of Otolaryngology, Inonu University Faculty of Medicine, Malatya, Turkey. mtkalcioglu@hotmail.com
authors.forename: M T
authors.initials: MT
authors.lastname: Kalcioglu
authors.forename: I
authors.initials: I
authors.lastname: Kuku
authors.forename: E
authors.initials: E
authors.lastname: Kaya
authors.forename: S
authors.initials: S
authors.lastname: Oncel
authors.forename: I
authors.initials: I
authors.lastname: Aydogdu
mesh_terms: D000293:Adolescent; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000009:adverse effects*; D001299:Audiometry; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D017809:Fatal Outcome; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D016399:Lymphoma, T-Cell / Q000175:diagnosis / Q000188:drug therapy*; D018570:Risk Assessment; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine