Profiling of impurities in p-methoxymethamphetamine (PMMA) by means of SPE/TLC method. Examination of the influence of experimental conditions according to 2(4) factorial.
In the present paper profiling of impurities in p-methoxymethamphetamine (PMMA) by means of SPE/TLC is reported. PMMA was synthesised by Leuckart procedure. The influence of experimental conditions on the profile quality was investigated. The experiments were carried out according to a 2(4) factorial. The proposed characteristics of the profile quality (optimisation criterions) are based on a matrix presentation of TLC patterns. They take into account, simultaneously, the number of spots revealed, differences between R(f) values and intensity of fluorescence.
Kochana
J
J
Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060 Cracow, Poland. kochana@chemia.uj.edu.pl
Wilamowski
J
J
Parczewski
A
A
D000662:Amphetamines / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D004340:Drug Contamination; D005554:Forensic Medicine / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry; D006213:Hallucinogens / Q000737:chemistry*; D015394:Molecular Structure
D000662:Amphetamines; D006213:Hallucinogens; C100230:4-methoxyamphetamine