title: Balloon mitral commissurotomy in juvenile rheumatic mitral stenosis: a ten-year clinical and echocardiographic actuarial results.
abstract: OBJECTIVE
  To evaluate the safety, efficacy and long-term actuarial results of balloon mitral commissurotomy in young patients with severe rheumatic mitral stenosis.
  
  
  RESULTS
  Event-free survival and freedom from restenosis were analyzed in 110 patients 20 years old or younger (group 1) and compared with those of 554 adults (group 2). Young patients were less frequently in atrial fibrillation (6% vs 35%, P<0.001) and had less mitral valve deformities (echo score 5.9+/-2.1 vs 7.5+/-3.0, P<0.0001). Mitral valve area index by 2D-echo was of 0.66+/-0.1cm(2)/m(2)in group 1 and 0.67+/-0.1cm(2)/m(2)in group 2 (P=ns) and was larger in group 1 (1.5 vs 1.3 cm(2)/m(2)) after the procedure (P<0.0001). There were more complications in group 2 (8.4% vs 0%, P=0.01). Procedural success was obtained in 110 (100%) patients of group 1 vs 501 (92%) patients of group 2 (P<0.0001). At follow-up mitral valve area index was 1.34 cm(2)/m(2)in group 1 and 1.16 cm(2)/m(2)in group 2 (P<0.0001). At 10 years, freedom from restenosis was 61% in group 1 vs 71% in group 2 (P=0.35) and event-free survival was 74% and 69% respectively (P=0.15
  
  
  CONCLUSIONS
  Balloon mitral commissurotomy is safe and effective in young with rheumatic mitral stenosis and provides better immediate results than in adults. However long-term outcome was similar between the 2 groups: 2/3 of patients were alive and free from clinical events at 10 years.
authors.affiliation: Cardiology Department, Fattouma Bourguiba University Hospital, 5000 Monastir, Tunisia. hgamra@rns.tn
authors.forename: H
authors.initials: H
authors.lastname: Gamra
authors.forename: F
authors.initials: F
authors.lastname: Betbout
authors.forename: K
authors.initials: K
authors.lastname: Ben Hamda
authors.forename: F
authors.initials: F
authors.lastname: Addad
authors.forename: F
authors.initials: F
authors.lastname: Maatouk
authors.forename: Z
authors.initials: Z
authors.lastname: Dridi
authors.forename: S
authors.initials: S
authors.lastname: Hammami
authors.forename: M
authors.initials: M
authors.lastname: Abdellaoui
authors.forename: H
authors.initials: H
authors.lastname: Boughanmi
authors.forename: T
authors.initials: T
authors.lastname: Hendiri
authors.forename: M
authors.initials: M
authors.lastname: Ben Farhat
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002404:Catheterization / Q000379:methods*; D002648:Child; D018572:Disease-Free Survival; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000628:therapy*; D012008:Recurrence; D019233:Retreatment; D012214:Rheumatic Heart Disease / Q000150:complications*; D016019:Survival Analysis; D016896:Treatment Outcome