1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin.
It has been found that 1-methylnicotinamide (MNA+), a metabolite of nicotinamide, possesses significant anti-inflammatory properties. MNA+ is chemically stable, non-toxic and well tolerated. MNA+ can be used to treat wide variety of diseases and disorders and the use of this compound provides certain advantages over the use of nicotinamide.
Gebicki
Jerzy
J
Institute of Applied Radiation Chemistry, Technical University, Zeromskiego 116, PL 90-924 Lódź, Poland. jgebicki@ck-sg.p.lodz.pl
Sysa-Jedrzejowska
Anna
A
Adamus
Jan
J
Woźniacka
Anna
A
Rybak
Małgorzata
M
Zielonka
Jacek
J
D000287:Administration, Topical; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000737:chemistry / Q000378:metabolism*; D003872:Dermatitis / Q000378:metabolism / Q000517:prevention & control; D004311:Double-Blind Method; D005782:Gels; D006801:Humans; D009536:Niacinamide / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*; D010865:Pilot Projects
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005782:Gels; D009536:Niacinamide; C024058:N(1)-methylnicotinamide