Migration of monocytes/macrophages in vitro and in vivo is accompanied by MMP12-dependent tunnel formation and by neovascularization.
Anghelina
M
M
Dorothy M. Davis Heart and Lung Research Institute, Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Schmeisser
A
A
Krishnan
P
P
Moldovan
L
L
Strasser
R H
RH
Moldovan
N I
NI
D000818:Animals; D001161:Arteriosclerosis / Q000201:enzymology / Q000209:etiology / Q000473:pathology; D002460:Cell Line; D002465:Cell Movement / Q000502:physiology; D018932:Chemokine CCL2 / Q000235:genetics / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008264:Macrophages / Q000502:physiology*; D053508:Matrix Metalloproteinase 12; D008666:Metalloendopeptidases / Q000502:physiology*; D051379:Mice; D008822:Mice, Transgenic; D009000:Monocytes / Q000502:physiology*; D009389:Neovascularization, Pathologic; D018919:Neovascularization, Physiologic; D020794:Receptor Protein-Tyrosine Kinases / Q000502:physiology; D042787:Receptor, TIE-2
D018932:Chemokine CCL2; D020794:Receptor Protein-Tyrosine Kinases; D042787:Receptor, TIE-2; D008666:Metalloendopeptidases; C507122:MMP12 protein, human; D053508:Matrix Metalloproteinase 12