title: [Diagnosis of stress preceding the fatal outcome].
abstract: Postmortem examinations of cytomedines of internal organs in 181 men showed a possibility to use their (cytomedines') quantitative and qualitative characteristics as diagnostic criteria of stress influencing the human organism shortly before the death onset. Bioregulatory peptides were obtained by using Morozov's and Khavinson's method of acetous extraction. The composition of cytomedines was determined by spectrophotometer, while their biological activity (BA) was studied through affecting the phagocytic activity of blood neutrophils. It was concluded that, under stress, there are a significant inhibition of BA and a reduced count of cytomedines in the internal organs. The found data can be used to detect the stress preceding death.
authors.forename: G I
authors.initials: GI
authors.lastname: Avkhodiev
authors.forename: O V
authors.initials: OV
authors.lastname: Kuz'mina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000032:analysis* / Q000378:metabolism; D011180:Postmortem Changes; D013312:Stress, Physiological / Q000175:diagnosis* / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D010455:Peptides; C053892:cytomedins