Parasympathetic nervous system dysfunction in primary Sjögren's syndrome.
In the past sicca syndromes were attributed to destruction of glandular tissue. It is now thought that cytokines, autoantibodies, and parasympathetic nervous system dysfunction all have an important role in the xerostomia and xerophthalmia in Sjögren's syndrome.
Hocevar
A
A
Department of Rheumatology, Medical Centre Ljubljana, SI 1000 Ljubljana, Slovenia.
Tomsic
M
M
Praprotnik
S
S
Hojnik
M
M
Kveder
T
T
Rozman
B
B
D001342:Autonomic Nervous System Diseases / Q000503:physiopathology*; D006801:Humans; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D012859:Sjogren's Syndrome / Q000503:physiopathology*; D009435:Synaptic Transmission; D014985:Xerophthalmia / Q000503:physiopathology; D014987:Xerostomia / Q000503:physiopathology