title: Hyperacute rejection of living related kidney graft caused by IgG endothelial specific antibodies with a negative monocyte cross-match.
abstract: We present a case report of a 30-year-old man, who hyperacutely rejected a blood group identical, HLA-haploidentical living related kidney graft in spite of the fact that he had never been immunized. Anti-endothelial IgG antibodies that did not react with monocytes were detected with flow cytometry, on a panel of human umbilical cord cells in his serum retrospectively. On the basis of this experience we put for consideration the possibility of regular examination of non-HLA antibodies in potential living graft recipients.
authors.affiliation: Slovak Center for Organ Transplantation Bratislava, Slovakia. barbarag@kiwwi.sk
authors.forename: Barbara
authors.initials: B
authors.lastname: Grandtnerová
authors.forename: L'udovít
authors.initials: L
authors.lastname: Laca
authors.forename: Eva
authors.initials: E
authors.lastname: Jahnová
authors.forename: Miroslava
authors.initials: M
authors.lastname: Horváthová
authors.forename: Vladimír
authors.initials: V
authors.lastname: Baláz
authors.forename: Blanka
authors.initials: B
authors.lastname: Hovoricová
authors.forename: Peter
authors.initials: P
authors.lastname: Hudec
authors.forename: Mária
authors.initials: M
authors.lastname: Zarnovicanová
mesh_terms: D000208:Acute Disease; D000328:Adult; D000906:Antibodies / Q000276:immunology*; D000918:Antibody Specificity; D004730:Endothelium, Vascular / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D016030:Kidney Transplantation / Q000276:immunology*; D019520:Living Donors; D008297:Male; D009000:Monocytes / Q000276:immunology*
chemical_list: D000906:Antibodies; D007074:Immunoglobulin G