title: Progressive supranuclear palsy phenotype secondary to CADASIL.
abstract: OBJECTIVE
  To report a unique case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy manifesting as a progressive supranuclear palsy phenotype, thereby expanding its recognized presentations.
  
  
  METHODS
  Review of the pertinent literature from MEDLINE, cross-referencing cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, progressive supranuclear palsy, and parkinsonism. Description of a 60-year-old woman who presented with a several year history of step-wise, progressive parkinsonism secondary to cerebral autosomal dominant arteriopathy.
  
  
  RESULTS
  Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy may present with a progressive supranuclear phenotype.
  
  
  CONCLUSIONS
  Parkinsonism, including a progressive supranuclear palsy phenotype, is one of a growing number of recognized ways that cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy may present.
authors.affiliation: Department of Neurology, Mayo Clinic Foundation, 200 First Street SW, Rochester, MN 55905, USA. vangerpen.jay@mayo.edu
authors.forename: J A
authors.initials: JA
authors.lastname: Van Gerpen
authors.forename: J E
authors.initials: JE
authors.lastname: Ahlskog
authors.forename: G W
authors.initials: GW
authors.lastname: Petty
mesh_terms: D015161:Dementia, Multi-Infarct / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013494:Supranuclear Palsy, Progressive / Q000209:etiology*; D013577:Syndrome