title: [Restrictive cardiomyopathy due to myofibrillar myopathy].
abstract: Early and severe cardiomyopathy may be related to myofibrillar myopathy.
  
  
  METHODS
  We report a one-year-old child with early and severe restrictive cardiomyopathy. The diagnosis of myofibrillar myopathy was obtained on skeletal muscle and endomyocardial biopsies. The patient died despite inotropic support and mechanical ventilation.
  
  
  CONCLUSIONS
  Myofibrillar myopathy must be considered when exploring the etiology of a restrictive cardiomyopathy in children. The diagnosis relies on examination of endomyocardial or skeletal muscle biopsy samples.
authors.affiliation: Service de cardiologie pédiatrique, hôpital de la Timone-Enfant, 13005 Marseille, France.
authors.forename: I
authors.initials: I
authors.lastname: Ligi
authors.forename: A
authors.initials: A
authors.lastname: Fraisse
authors.forename: B
authors.initials: B
authors.lastname: Chabrol
authors.forename: O
authors.initials: O
authors.lastname: Paut
authors.forename: F
authors.initials: F
authors.lastname: Bourlon
authors.forename: D
authors.initials: D
authors.lastname: Métras
authors.forename: J L
authors.initials: JL
authors.lastname: Bonnet
authors.forename: J F
authors.initials: JF
authors.lastname: Pellissier
mesh_terms: D001706:Biopsy; D002313:Cardiomyopathy, Restrictive / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008297:Male; D018485:Muscle Fibers, Skeletal / Q000648:ultrastructure*; D009135:Muscular Diseases / Q000150:complications*; D009206:Myocardium / Q000648:ultrastructure; D009210:Myofibrils / Q000648:ultrastructure*