title: [Case of scleroderma with congestive heart failure in which myocardial injury was detected by scintigraphy].
abstract: A 38-year-old woman with systemic sclerosis was admitted to our hospital because of dyspnea and finger ulcer. Chest X-p showed cardiomegaly and pleural effusion. Echocardiogram revealed diffuse hypokinesis of the left ventricle (ejection fraction 32%). Thallium scintigraphy demonstrated patchy perfusion defects. She was diagnosed as having congestive heart failure due to myocardial fibrosis, and was treated successfully with diuretics, cardiotonics, and beta-blocker. Scintigraphy may be useful to detect an early cardiac involvement in patients with systemic sclerosis, and intense pharmacological treatment might be started even before the patient develops symptoms.
authors.affiliation: Department of Internal Medicine, Ohme Municipal General Hospital.
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Kosugi
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Sakurai
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000328:Adult; D005260:Female; D005355:Fibrosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D006321:Heart / Q000000981:diagnostic imaging*; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D009206:Myocardium / Q000473:pathology; D011877:Radionuclide Imaging; D012595:Scleroderma, Systemic / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists