title: Human health and environmental risk assessment: the need for a more harmonised and integrated approach.
abstract: Historically the procedures for human risk assessment and for risk assessment have developed separately with different terminologies and separate data bases. The identification that there are many common features and that sharing of certain types of data for risk assessment purposes would be beneficial is a driver towards a better integration of their procedures. Risk assessors are facing increasing challenges from governments, stimulated by public pressure for (i) human and environmental risk assessments of an ever growing number of products and processes, (ii) further restrictions of the use of animal tests and human studies on ethical grounds, (iii) the requirement to demonstrate that the assessments are independent, transparent and of high quality, (iv) reducing resources in particular a diminishing number of individuals with the scientific depth, breadth and independence act as risk assessors, (v) the need to incorporate new sciences continually and new discoveries into the risk assessment process. It is important for society that these challenges are met successfully. This requires changes in both risk assessment procedures and in the infrastructure needed to support them. Risk assessment is a science based process for establishing the likelihood of adverse effects to human health and to the environment from specific chemical, biological and physical agents. In the last few years there has been a renewed effort, by international bodies such as WHO, OECD and the EU, to achieve a more integrated and harmonised approach to risk assessment. Before examining the potential for a more integrated approach to risk assessment it is timely to consider the key factors which have led to the current position.
authors.affiliation: Toxicology and Environmental Health, University of Surrey, Guildford, Surrey GU2 7XH, UK. j.bridges@surrey.ac.uk
authors.forename: Jim
authors.initials: J
authors.lastname: Bridges
mesh_terms: D016208:Databases, Factual; D004782:Environmental Health / Q000592:standards*; D004785:Environmental Pollutants / Q000506:poisoning*; D006801:Humans; D010934:Planning Techniques; D018570:Risk Assessment / Q000379:methods* / Q000592:standards
chemical_list: D004785:Environmental Pollutants