title: Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria.
abstract: Photorhabdus is an insect-pathogenic bacterium in which oral toxicity to insects is found in two distinct taxonomic groups. Using a DNA microarray and comparative genomics, we show that oral toxicity is associated with toxin complex genes tcaABC and that this locus can be mobilized or deleted within different strains.
authors.affiliation: Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, United Kingdom.
authors.forename: Judit
authors.initials: J
authors.lastname: Marokhazi
authors.forename: Nicholas
authors.initials: N
authors.lastname: Waterfield
authors.forename: Gaelle
authors.initials: G
authors.lastname: LeGoff
authors.forename: Edward
authors.initials: E
authors.lastname: Feil
authors.forename: Richard
authors.initials: R
authors.lastname: Stabler
authors.forename: Jason
authors.initials: J
authors.lastname: Hinds
authors.forename: Andras
authors.initials: A
authors.lastname: Fodor
authors.forename: Richard H
authors.initials: RH
authors.lastname: ffrench-Constant
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D020869:Gene Expression Profiling; D007313:Insecta / Q000382:microbiology*; D009348:Nematoda / Q000382:microbiology; D020411:Oligonucleotide Array Sequence Analysis; D020637:Photorhabdus / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D014774:Virulence; D037521:Virulence Factors / Q000235:genetics / Q000378:metabolism*; D020593:Xenorhabdus / Q000145:classification / Q000235:genetics / Q000472:pathogenicity
chemical_list: D001426:Bacterial Proteins; D037521:Virulence Factors