Recurrent episodes of deep vein thrombosis in a young man.
We present the case of a 32-year-old man suffering from recurrent episodes of deep vein thrombosis (DVT). He was heterozygous for the G1691A mutation in the Factor V gene. His father was heterozygous for the same mutation and had a unique episode of DVT after a fracture of the tibia. Genetic predisposition significantly influences the prevalence of thrombotic events, however, additional unknown factors may be involved in the initiation and recurrence of venous thromboembolism.
Giotopoulou
S
S
Hematology Laboratory, Unit of Mocolecular Biology, University Hospital of Ioannina, Ioannina, Greece.
Giafis
K
K
Dokou
E
E
Tsaousi
C
C
Kolaitis
N
N
Vartholomatos
G
G
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D006115:Greece; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010690:Phlebography; D011152:Popliteal Vein / Q000000981:diagnostic imaging / Q000473:pathology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin