[Plasma procalcitonin in rheumatic diseases].
Data on the origin and biological function of procalcitonin, the pro-hormone of calcitonin, are scarce. Since this peptide can be induced in bacterial invasive infections, serum procalcitonin levels may be useful in differential diagnosis of systemic inflammatory response syndrome. This review will focus on the clinical significance of changes in serum procalcitonin levels in patients with connective tissue diseases and other rheumatic disorders.
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Cattedra e Unità Operativa di Reumatologia, Pavia, Italy. montecucco@smatteo.pv.it
Caporali
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Perotti
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Montecucco
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D001172:Arthritis, Rheumatoid / Q000097:blood / Q000175:diagnosis; D001327:Autoimmune Diseases / Q000097:blood* / Q000175:diagnosis*; D001424:Bacterial Infections / Q000097:blood / Q000175:diagnosis; D002116:Calcitonin / Q000097:blood* / Q000235:genetics / Q000502:physiology; D015740:Calcitonin Gene-Related Peptide; D003240:Connective Tissue Diseases / Q000097:blood / Q000175:diagnosis; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000097:blood / Q000175:diagnosis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000175:diagnosis; D009181:Mycoses / Q000097:blood / Q000175:diagnosis; D011498:Protein Precursors / Q000097:blood* / Q000235:genetics / Q000502:physiology; D012216:Rheumatic Diseases / Q000097:blood* / Q000175:diagnosis*; D014777:Virus Diseases / Q000097:blood / Q000175:diagnosis
C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide