Clonorchis sinensis: immunolocalization of 26 kDa glutathione S-transferase in adult worms.
A mu-class glutathione S-transferase (Cs26GST) of molecular mass 26 kDa was characterized from Clonorchis sinensis. In adult C. sinensis, the distribution of the Cs26GST was investigated by immuno-histochemistry and electron microscopy. Cs26GST was localized to the tegument and parenchyma. Immunogold labeling was strong in the tegumental cell bodies and moderate in the tegument and ova in the oviduct. It is suggested that Cs26GST plays a role in the metabolism and fecundity of C. sinensis.
Hong
Sung-Jong
SJ
Department of Parasitology, Chung-Ang University College of Medicine, Tongjak-gu, Seoul 156-756, South Korea. hongsj@cau.ac.kr
Kim
Tae Yun
TY
Kang
Shin-Yong
SY
Yu
Jae-Ran
JR
Song
Kye-Yong
KY
Cho
Seung-Yull
SY
D000818:Animals; D003004:Clonorchis sinensis / Q000201:enzymology* / Q000648:ultrastructure; D003530:Cyprinidae; D005982:Glutathione Transferase / Q000032:analysis* / Q000737:chemistry / Q000276:immunology; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron; D008970:Molecular Weight; D011817:Rabbits
D005982:Glutathione Transferase