title: Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster.
abstract: We have recently identified in Drosophila melanogaster a new gene encoding a nuclear protein, DIP1. Here we report the developmental expression and the finding that DIP1 subcellular localization is in the nucleus and at the nuclear periphery during interphase in embryos. Interestingly, in humans, DIP1 antibody identified signals in nuclei from cultured cells and reacted with a rough 30kDa protein in Western blotting experiments, demonstrating evolutionary conservation.
authors.affiliation: Department of Life Sciences, University of Naples II, Caserta, Italy. bruna.defelice@unina2.it
authors.forename: Bruna
authors.initials: B
authors.lastname: De Felice
authors.forename: Robert Roy
authors.initials: RR
authors.lastname: Wilson
authors.forename: Paolo
authors.initials: P
authors.lastname: Mondola
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Matrone
authors.forename: Simona
authors.initials: S
authors.lastname: Damiano
authors.forename: Corrado
authors.initials: C
authors.lastname: Garbi
authors.forename: Luigi
authors.initials: L
authors.lastname: Nezi
authors.forename: Tin Tin
authors.initials: TT
authors.lastname: Su
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D029721:Drosophila Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D016415:Sequence Alignment; D014157:Transcription Factors
chemical_list: C485815:CCNDBP1 protein, human; C410062:DISCO Interacting Protein 1, Drosophila; D029721:Drosophila Proteins; D009687:Nuclear Proteins; D014157:Transcription Factors