Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris.
Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations.
Sheu
Jyh-Horng
JH
Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, Republic of China. sheu@mail.nsysu.edu.tw
Huang
Long-Fei
LF
Chen
Shin-Pin
SP
Yang
Yi-Lea
YL
Sung
Ping-Jyun
PJ
Wang
Guey-Horng
GH
Su
Jui-Hsin
JH
Chao
Chih-Hua
CH
Hu
Wan-Ping
WP
Wang
Jeh-Jeng
JJ
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010100:Oxygen / Q000737:chemistry; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification*; D013624:Taiwan
D013256:Steroids; D010100:Oxygen