title: Accelerated intravenous rehydration.
abstract: To determine whether accelerated intravenous (i.v.) rehydration using a new Isotonic Dehydration Worksheet results in: (1) complications in serum sodium or volume status, and (2) decreased duration of i.v. fluid therapy or length of hospital stay, we conducted a retrospective cohort study utilizing chart review. An intervention group of 98 children, ages 1 month to 12 years, treated with the Isotonic Dehydration Worksheet from December 2000 through March 2001 was compared to a control group of 61 children treated from December 1999 through March 2000 before introduction of the Worksheet. Complication rates were low and did not differ between the 2 groups. Mean unadjusted lengths of i.v. therapy (35.3 vs. 33.7 hours) and of hospital stay (47.0 vs. 49.3 hours) were not significantly different between the 2 groups. Introduction of an accelerated rehydration protocol was well-tolerated by patients but did not result in a significant decrease in the outcome variables examined. Other factors may have a greater impact on the outcome variables, and a prospective study to address these questions is planned.
authors.affiliation: Department of Pediatrics, Rainbow Babies and Children's Hospital and Case Western Reserve University, Cleveland, OH 44106, USA.
authors.forename: Usama
authors.initials: U
authors.lastname: Kanaan
authors.forename: Katherine MacRae
authors.initials: KM
authors.lastname: Dell
authors.forename: Jason
authors.initials: J
authors.lastname: Hoagland
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: O'Riordan
authors.forename: Lydia
authors.initials: L
authors.lastname: Furman
mesh_terms: D000284:Administration, Oral; D016022:Case-Control Studies; D003681:Dehydration / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D015532:Rehydration Solutions / Q000627:therapeutic use*; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D014883:Water-Electrolyte Imbalance / Q000175:diagnosis / Q000628:therapy
chemical_list: D015532:Rehydration Solutions