A sterically-encumbered, C2-symmetric chiral acetal for enhanced asymmetric induction in the Pauson-Khand reaction.
High levels of diastereoselection were achieved in the PKR of 1,6- and 1,7-cyclopropylidenynes bearing a bulky propargylic C(2)-symmetric acetal.
Krafft
Marie E
ME
Department of Chemistry and Biochemistry, The Florida State University, Tallahassee, Florida 32306-4390, USA. mek@chem.fsu.edu
Boñaga
Llorente V R
LV
Felts
Andrew S
AS
Hirosawa
Chitaru
C
Kerrigan
Sean
S