title: [About remodelling in connection with two cases of bone substitution].
abstract: Numerous possibilities are available for the reconstruction of facial bone defects. The materials utilized to fill such defects must satisfy various requirements. One of the most important being that they must undergo transformation into autologous bone tissue in the process of remodelling. A report is given of the long-term results of augmentations performed with different bone-substitute materials in two patients. In one case, augmentation was carried out with beta-tricalcium phosphate following the removal of a fibromyxoma. In the second case, three large cystic lesions in the mandible of a patient with Gorlin-Goltz syndrome were filled with beta-tricalcium phosphate, with a mixture of beta-tricalcium phosphate and platelet concentrate, or with hydroxyapatite of algal origin respectively. The process of ossification was checked at 6-months intervals by means of clinical and radiological (orthopantomogramms and 2D and 3D computertomogramms) methods. One year after the intervention, the site of the augmentation was in all cases occupied by hard tissue of good quality. With the given imaging procedures, it was difficult to distinguish between the original bone and the region filled with bone-substitute material. The 3D computertomogramm images indicated that the contours and quality of the new bone corresponded to the physiological and anatomical conditions. The bone-substitute materials applied in these cases fully satisfied the demands of transformation into bone (remodelling).
authors.affiliation: Szájsebészeti és Fogászati Klinika, Egyetem Fogorvostudományi Kar Budapest.
authors.forename: Norbert
authors.initials: N
authors.lastname: Velich
authors.forename: József
authors.initials: J
authors.lastname: Barabás
authors.forename: György
authors.initials: G
authors.lastname: Szabó
mesh_terms: D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use; D016723:Bone Remodeling; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use; D017886:Durapatite / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008437:Maxilla / Q000601:surgery*; D019647:Oral Surgical Procedures / Q000379:methods*; D016348:Osseointegration; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate; D017886:Durapatite; C018392:tricalcium phosphate