title: Acetophenone derivatives from Acronychia pedunculata.
abstract: Chemical investigation on the stem and root bark of Acronychia pedunculata has resulted in the isolation of five new acetophenones, namely, acronyculatins A (1), B (2), C (3), D (4), and E (5). The structures of these metabolites were established on the basis of their 1D and 2D NMR spectroscopic and mass spectrometric data and by CD spectroscopy. The antioxidant and antityrosinase activities of these five metabolites and acrovestone (6) were evaluated. Among these compounds, 6 showed marginal antioxidant and antityrosinase activities.
authors.affiliation: Department of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan, Republic of China.
authors.forename: Chung-Ren
authors.initials: CR
authors.lastname: Su
authors.forename: Ping-Chung
authors.initials: PC
authors.lastname: Kuo
authors.forename: Meei-Ling
authors.initials: ML
authors.lastname: Wang
authors.forename: Meei-Jen
authors.initials: MJ
authors.lastname: Liou
authors.forename: Amooru G
authors.initials: AG
authors.lastname: Damu
authors.forename: Tian-Shung
authors.initials: TS
authors.lastname: Wu
mesh_terms: D000098:Acetophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002942:Circular Dichroism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors*; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027821:Rutaceae / Q000737:chemistry*; D013624:Taiwan
chemical_list: D000098:Acetophenones; D000975:Antioxidants; D004791:Enzyme Inhibitors; C061305:acrovestone; D014442:Monophenol Monooxygenase