title: Peripapillary choroidal atrophy in sympathetic ophthalmia and management with triple-agent immunosuppression.
abstract: OBJECTIVE
  To describe the occurrence of peripapillary choroidal atrophy and experience with triple-agent immunosuppression in three cases of sympathetic ophthalmia.
  
  
  METHODS
  Retrospective chart review of three cases of sympathetic ophthalmia with peripapillary choroidal atrophy.
  
  
  RESULTS
  Three patients with sympathetic ophthalmia were managed with steroid pulse therapy and triple-agent immunosuppression. All three patients subsequently developed peripapillary choroidal atrophy.
  
  
  CONCLUSIONS
  Peripapillary choroidal atrophy can occur in sympathetic ophthalmia and may indicate a severe form of inflammation which would benefit from triple-agent immunosuppression.
authors.affiliation: Uvea Service, Sankara Nethralaya, Medical Research Foundation, Chennai, India. mrf@sankaranethralaya.org
authors.forename: Sudha K
authors.initials: SK
authors.lastname: Ganesh
authors.forename: Kannan M
authors.initials: KM
authors.lastname: Narayana
authors.forename: Jyotirmay
authors.initials: J
authors.lastname: Biswas
mesh_terms: D000328:Adult; D001284:Atrophy; D001379:Azathioprine / Q000627:therapeutic use; D002648:Child; D002829:Choroid / Q000473:pathology*; D015862:Choroid Diseases / Q000188:drug therapy* / Q000209:etiology*; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009879:Ophthalmia, Sympathetic / Q000150:complications* / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D012189:Retrospective Studies
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D001379:Azathioprine; D011241:Prednisone; D008775:Methylprednisolone