title: [A case of pulmonaly bulla infection with Mycobacterium fortuitum].
abstract: We report a case of bulla infection caused by Mycobacterium fortuitum. The patient was a 66 year-old female associated with interstitial pneumonitis. The chest X-ray film showed cavities with thick walls and niveau formation, which initially suggested pulmonary abscesses. The chest CT scan showed infiltrative shadows surrounding multiple bullae. Smears and cultures of the sputum were repeatedly positive for mycobacteria, which was identified to be M. fortuitum. By chemotherapy with imipenem/cilastatin sodium, clarithromycin, levofloxacin, and minocycline on the basis of susceptibility test, sputum converted to negative within 2 months, abnormal shadows on the roentgenogram and laboratory data showed improvement. There are no signs of recurrence after completion of the treatment for 12 months.
authors.affiliation: Department of Respiratory Medicine, Tenri Hospital.
authors.forename: Shigeo
authors.initials: S
authors.lastname: Hisamori
authors.forename: Kazukiyo
authors.initials: K
authors.lastname: Oida
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Taguchi
authors.forename: Eisaku
authors.initials: E
authors.lastname: Tanaka
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Inoue
authors.forename: Kouji
authors.initials: K
authors.lastname: Katoh
authors.forename: Minoru
authors.initials: M
authors.lastname: Sakuramoto
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Minaguchi
authors.forename: Yuuji
authors.initials: Y
authors.lastname: Maeda
authors.forename: Koh
authors.initials: K
authors.lastname: Maniwa
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Terada
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Ishimaru
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hata
mesh_terms: D000368:Aged; D001768:Blister / Q000188:drug therapy; D015377:Cilastatin / Q000008:administration & dosage*; D000077728:Cilastatin, Imipenem Drug Combination; D017291:Clarithromycin / Q000008:administration & dosage*; D004338:Drug Combinations; D004359:Drug Therapy, Combination / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage*; D064704:Levofloxacin; D017563:Lung Diseases, Interstitial / Q000150:complications; D008911:Minocycline / Q000008:administration & dosage; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D019907:Mycobacterium fortuitum; D015242:Ofloxacin / Q000008:administration & dosage; D011656:Pulmonary Emphysema / Q000188:drug therapy*
chemical_list: D004338:Drug Combinations; D015377:Cilastatin; D064704:Levofloxacin; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination; D015242:Ofloxacin; D008911:Minocycline; D017291:Clarithromycin