Hepatitis B virus DNA in sera of blood donors and of patients infected with hepatitis C virus and human immunodeficiency virus.
With the use of PCR, we searched for hepatitis B virus (HBV) DNA in serum samples from 415 HBsAg-negative, anti-HBc-positive patients: 150 were blood donors, 106 had only hepatitis C virus (HCV) infection, and 159 had human immunodeficiency virus (HIV) infection (of which 88 were HCV positive and 71 were HCV negative). HBV DNA was detected in 4% of blood donors, 3.4% of HIV- and HCV-positive patients, and 24% of HCV-positive patients.
Gonçales
Fernando Lopes
FL
Grupo de Estudos das Hepatites, Disciplina de Moléstias Infecciosas, Faculdade de Ciências Médicas, UNICAMP, Campinas, SP, Brazil. flgj@uol.com.br
Pereira
Josiane Silveira Felix
JS
Da Silva
Claudia
C
Thomaz
Glaucimari Roberto
GR
Pavan
Maria Helena Postal
MH
Fais
Viviane Cristina
VC
Magna
Luis Alberto
LA
Gonçales
Neiva Sellan Lopes
NS
D000328:Adult; D001782:Blood Donors; D001938:Brazil / Q000453:epidemiology; D015897:Comorbidity; D004279:DNA, Viral / Q000097:blood*; D005188:False Negative Reactions; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D018023:HIV Seronegativity; D006679:HIV Seropositivity; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D016133:Polymerase Chain Reaction; D015995:Prevalence; D014766:Viremia / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology
D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies