title: [Analysis of the poly-genes expression changes in liver by gene expression profile chip in gut ischemia-reperfusion rats].
abstract: OBJECTIVE
  To investigate the difference of poly-genes expression between control and gut ischemia-reperfusion rats.
  
  
  METHODS
  One thousand one hundred and seventy-six known genes expression in the liver was investigated by means of the cDNA microarray technology to reveal the differential expression genes between control and gut ischemia-reperfusion rats.
  
  
  RESULTS
  The analysis data of the cDNA microarray showed that there were 111 genes expression changed over 5 times including 64 genes upregulated and 47 genes downregulated, some of which had not been reported to associated with gut ischemia-reperfusion injury.
  
  
  CONCLUSIONS
  There are many structural and functional genes expression changed in liver of gut ischemia-reperfusion rats, which might be involved in the initiation and the development of SIRS and MODS.
authors.affiliation: Research Department of Burn Institute, 304th Hospital of People's Liberation Army, Beijing 100037, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lü
authors.forename: Jun-you
authors.initials: JY
authors.lastname: Li
authors.forename: Sen
authors.initials: S
authors.lastname: Hu
authors.forename: Hua
authors.initials: H
authors.lastname: Jin
authors.forename: Dan
authors.initials: D
authors.lastname: Sun
authors.forename: Zhi-yong
authors.initials: ZY
authors.lastname: Sheng
mesh_terms: D000818:Animals; D015870:Gene Expression; D007410:Intestinal Diseases / Q000235:genetics* / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D020411:Oligonucleotide Array Sequence Analysis; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000235:genetics* / Q000378:metabolism; D059467:Transcriptome