GLIA: A reassessment based on novel data on the developing and mature central nervous system.
Several studies on neurobiology have contributed to our understanding of the genesis, survival and death of neurons, unquestionably the stars of the Central Nervous System (CNS). However, they would not be so famous without their close associates: the glial cells. Since novel studies have demonstrated new and important functions for glial cells, they are beginning to gain significant importance in brain research to allow us to reinterpret long known functions on the basis of new concepts. Here, we review recent progress in our understanding of the role of glial cells in the biology of tissue development and maturation.
Villegas
Santiago Nahuel
SN
Molecular Biology, IMBICE, Camino Belgrano y 526, CC 403, 1900, La Plata, Argentina.
Poletta
Fernando Adrián
FA
Carri
Néstor Gabriel
NG
D001921:Brain / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D002450:Cell Communication / Q000502:physiology; D002490:Central Nervous System / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology; D016207:Cytokines / Q000276:immunology / Q000502:physiology; D051100:Glial Cell Line-Derived Neurotrophic Factor; D006801:Humans; D009414:Nerve Growth Factors / Q000502:physiology; D019636:Neurodegenerative Diseases / Q000473:pathology / Q000503:physiopathology; D009457:Neuroglia / Q000166:cytology / Q000378:metabolism* / Q000502:physiology
D016207:Cytokines; C495039:GDNF protein, human; D051100:Glial Cell Line-Derived Neurotrophic Factor; D009414:Nerve Growth Factors