Stemocurtisine, the first pyrido[1,2-a]azapine Stemona alkaloid.
A new pentacyclic stemona alkaloid, stemocurtisine (2), with a novel pyrido[1,2-a]azapine A,B-ring system, has been isolated from a root extract of Stemona curtisii. The structure and relative stereochemistry was determined by spectral data interpretation and X-ray crystallography.
Mungkornasawakul
Pitchaya
P
Division of Environmental Sciences, Chiang Mai University, Chiang Mai 50202, Thailand.
Pyne
Stephen G
SG
Jatisatienr
Araya
A
Supyen
Damrat
D
Lie
Wilford
W
Ung
Alison T
AT
Skelton
Brian W
BW
White
Allan H
AH
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D041901:Stemonaceae / Q000737:chemistry*; D013785:Thailand
D000470:Alkaloids; D005663:Furans; D006576:Heterocyclic Compounds, 4 or More Rings; C480054:stemocurtisine