title: Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.
authors.affiliation: Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Sasaki
authors.forename: Takaharu
authors.initials: T
authors.lastname: Taketomi
authors.forename: Reiko
authors.initials: R
authors.lastname: Kato
authors.forename: Kazuko
authors.initials: K
authors.lastname: Saeki
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nonami
authors.forename: Mika
authors.initials: M
authors.lastname: Sasaki
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Kuriyama
authors.forename: Naoaki
authors.initials: N
authors.lastname: Saito
authors.forename: Masafumi
authors.initials: M
authors.lastname: Shibuya
authors.forename: Akihiko
authors.initials: A
authors.lastname: Yoshimura
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D004789:Enzyme Activation / Q000502:physiology; D005346:Fibroblast Growth Factors / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins; D020935:MAP Kinase Signaling System / Q000502:physiology; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011485:Protein Binding; D019908:Proto-Oncogene Proteins c-raf / Q000378:metabolism*; D040301:Vascular Endothelial Growth Factor Receptor-2 / Q000378:metabolism; D018631:ras Proteins / Q000378:metabolism*
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D009419:Nerve Tissue Proteins; C499038:SPRY4 protein, human; C499037:Spry4 protein, mouse; D005346:Fibroblast Growth Factors; D040301:Vascular Endothelial Growth Factor Receptor-2; D019908:Proto-Oncogene Proteins c-raf; D020928:Mitogen-Activated Protein Kinases; D018631:ras Proteins