Screening for functional genes related to a novel gene, AngRem104, in human mesangial cells by cDNA microarray.
AngRem104 is a novel gene recently identified in human mesangial cells induced by angiotensin II. cDNA microarray was performed to screen the functional genes related to AngRem104. Thirty-one genes were up-regulated while 2 genes were down-regulated. Of all the up-regulated genes, fibronectin, one of the major extracellular matrixes, was up-regulated with over-expression of AngRem104.
Liang
Xiu-Bin
XB
Renal Division of Peking University First Hospital, Institute of Nephrology, Peking University, Beijing 100034, PR China.
Zhang
Hong
H
Zhou
An-Yu
AY
Wang
Hai-Yan
HY
D005353:Fibronectins / Q000096:biosynthesis / Q000235:genetics; D020869:Gene Expression Profiling / Q000379:methods; D005786:Gene Expression Regulation / Q000235:genetics*; D005920:Glomerular Mesangium / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D009687:Nuclear Proteins / Q000096:biosynthesis* / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000235:genetics; D014162:Transfection
D005353:Fibronectins; D009687:Nuclear Proteins; D011994:Recombinant Proteins