[Small cell lung carcinoma].
In most of the cases, small cell lung cancer is diagnosed at the extensive disease stage. Regarding the micrometastatic process, it might be considered as a metastatic disease in almost all cases. Therefore, chemotherapy is the cornerstone of small cell lung cancer therapy. Cisplatin and VP-16-based combinations are recommended. Chemotherapy alone remains the only recommended therapy in extensive disease, whereas radiochemotherapy is the treatment of limited disease. Concomitant or alternate modalities are acceptable standards in this latter setting. Prophylactic cranial irradiation is recommended for complete responders with initially limited disease.
Pujol
Jean-Louis
JL
Unité d'oncologie thoracique Hôpital Arnaud-de-Villeneuve Centre hospitalier universitaire et Languedoc Mutualité nouvelles technologies 34295 Montpellier. pujol@cyber-sante.org
Quantin
Xavier
X
Jacot
William
W
Boher
Jean-Marie
JM
Molinier
Olivier
O
Godard
Philippe
P
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant