[The results of randomized controlled trial of low-dose radiation for wet-type age-related macular degeneration on a 1 year term basis].
OBJECTIVE
Evaluation of low dose radiation therapy to the wet-type age-related macular degeneration (AMD) located at the fovea centralis.


METHODS
Patients were irradiated with 10 fractions of 2 Gy external beam or just observed. Between the treated(39) and untreated (31) cases, there was no significant difference in gender, age, initial visual acuity, or size of the neovascular membrane.


RESULTS
With the follow-up of 12 months, the visual acuity was significantly well preserved and the size of the neovascular membrane was decreased.


CONCLUSIONS
These results indicate that low dose irradiation is effective for the wet-type AMD of the stage we treated in the present study.
D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014792:Visual Acuity