[A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC].
The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.
Sakaguchi
Yoshihisa
Y
Dept. of Surgery, Fukuoka Higashi National Hospital.
Kabashima
Akira
A
Kuma
Sosei
S
Kajiyama
Kiyoshi
K
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003082:Colectomy; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005467:Floxuridine / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D012074:Remission Induction
D005467:Floxuridine; D016685:Mitomycin; C025034:doxifluridine