Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. II. Structure elucidation.
The structures of takanawaenes A, B and C, novel antifungal antibiotics produced by Streptomyces sp. K99-5278, were elucidated by various spectroscopic analyses including UV and NMR, and spectrometric analyses including MS. They have the common skeleton of a 28-membered pentaene macrolide.
Fukuda
Takashi
T
Kitasato Institute for Life Sciences, Kitasato University and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Kim
Yong-Pil
YP
Iizima
Kousuke
K
Tomoda
Hiroshi
H
Omura
Satoshi
S
D000935:Antifungal Agents / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011090:Polyenes / Q000737:chemistry*
D000935:Antifungal Agents; D007783:Lactones; D011090:Polyenes; C476106:takanawaene A; C476108:takanawaene B; C476109:takanawaene C