title: [Clinico-etiological study of 116 children with acquired damage to the central nervous system during the last decade in Niigata Prefecture].
abstract: One hundred and sixteen children with an acquired damage to the central nervous system (CNS) during the last decade were studied to determine the causes and sequelae and to find strategies for prevention. The etiology was CNS infections and related disorders in 46 cases (39.4%), non-infectious diseases (epileptic, hypoxic etc.) in 16 cases (13.8%), iatrogenic brain injury in 15 cases (12.9%), accident-related brain damage in 31 cases (26.7%), and vascular disorders in 8 cases (6.9%). Since infections and accidents accounted for as much as 66.4%, prevention of their sequelae is important. Of 37 patients (31.9%) with severe motor and intellectual disabilities syndrome (SMIDS), 18 were due to infectious diseases. SMIDS cases accounted for 39.1% of the infectious diseases group, 25% of the non-infectious diseases group, 40% of the iatrogenic group, 25.8% of the accident-related group and 12.5% of the vascular group. The prevalence rate of acquired CNS damage was estimated to be 0.5/10(3)/year and that of SMIDS due to acquired damage to be 0.16/10(3)/year. A monitoring system for patients with an acquired brain damage and for their treatment is important.
authors.affiliation: Department of Pediatrics, Niigata Prefecture Hamagumi Medical Rehabilitation Center for Handicapped Children, Niigata.
authors.forename: Megumu
authors.initials: M
authors.lastname: Tojo
authors.forename: Hatsumi
authors.initials: H
authors.lastname: Nitta
mesh_terms: D002493:Central Nervous System Diseases / Q000453:epidemiology / Q000209:etiology*; D002494:Central Nervous System Infections / Q000453:epidemiology / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D015995:Prevalence