title: Zygomycotic infection of the neonatal upper extremity.
abstract: Zygomycosis is a rare fungal infection that may present as a necrotizing soft tissue infection in the neonate. This report illustrates the typical presentation of a premature, infant with a rapidly progressive soft tissue necrotizing infection of his upper extremity at an intravenous site. Early diagnosis with tissue biopsy confirmed the diagnosis of Zygomycosis. Successful treatment required systemic amphotercin B and aggressive debridement requiring through-the-elbow amputation for survival.
authors.affiliation: Department of Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
authors.forename: Erika
authors.initials: E
authors.lastname: Scheffler
authors.forename: Grant G
authors.initials: GG
authors.lastname: Miller
authors.forename: Dale A
authors.initials: DA
authors.lastname: Classen
mesh_terms: D000671:Amputation, Surgical; D000935:Antifungal Agents / Q000627:therapeutic use; D001132:Arm; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D008297:Male; D018461:Soft Tissue Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D020096:Zygomycosis / Q000175:diagnosis* / Q000628:therapy
chemical_list: D000935:Antifungal Agents