[Estimation of the severity of metabolic disorders in children with newly diagnosed insulin dependent diabetes mellitus (IDDM)].
The objective of this study was to estimate the severity of metabolic disorders at onset in children with insulin dependent diabetes mellitus (IDDM). Biochemical results taken at onset of IDDM were analysed in 158 children on their admission. Metabolic acidosis was found in 37.97% of those and ketoacidosis was confirmed in 18.99% children. Mean values of biochemical parameters are similar to those reported in the others European countries. The most severe changes of the acid-base balance parameters were observed in youngest children (1-4 y.o) living in the rural areas (pH, 7.22, HCO3- 10.2 mmol/l, BE - 16.06 mmol/l, p=0.05); this should suggest that those children are watchfully observed and IDDM should be always be considered as a possible cause of any alarming symptoms which occur.
Charemska
Dorota
D
Oddział Alergologii, Pneumologii i Chorób Metabolicznych, Wojewódzki Specjalistyczny Szpital Dzieciecy, ul. Zołnierska 18, 10-561 Olsztyn, Poland.
Przybyszewski
Borys
B
Klonowska
Bozenna
B
D000293:Adolescent; D000367:Age Factors; D001639:Bicarbonates / Q000097:blood*; D001786:Blood Glucose / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology*; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008297:Male; D011044:Poland; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D014505:Urban Population / Q000706:statistics & numerical data
D001639:Bicarbonates; D001786:Blood Glucose; D006442:Glycated Hemoglobin