title: Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. II. Structure elucidation.
abstract: The structures of takanawaenes A, B and C, novel antifungal antibiotics produced by Streptomyces sp. K99-5278, were elucidated by various spectroscopic analyses including UV and NMR, and spectrometric analyses including MS. They have the common skeleton of a 28-membered pentaene macrolide.
authors.affiliation: Kitasato Institute for Life Sciences, Kitasato University and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukuda
authors.forename: Yong-Pil
authors.initials: YP
authors.lastname: Kim
authors.forename: Kousuke
authors.initials: K
authors.lastname: Iizima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tomoda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Omura
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011090:Polyenes / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D007783:Lactones; D011090:Polyenes; C476106:takanawaene A; C476108:takanawaene B; C476109:takanawaene C