Influence of antipsychotic agents on neurological soft signs and dyskinesia in first episode psychosis.
First episode psychosis patients treated with atypical antipsychotics had significantly fewer signs of dyskinesia than patients treated with classical antipsychotics, but there were no significant differences regarding the total number of neurological soft signs (NSS). This suggests that the type of antipsychotic medication does not influence NSS, but that atypical antipsychotics are associated with less dyskinesia in the early stages of treatment.
Boks
Marco P M
MP
Nottinghamshire Healthcare Trust, Queens Medical Centre, Psychiatry Outpatients, B-floor South Block, Nottingham NG7 2UH, UK. m_boks@hotmail.com
Liddle
Peter F
PF
Russo
Sascha
S
Knegtering
Rikus
R
van den Bosch
Robert Jan
RJ
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D009460:Neurologic Examination / Q000379:methods; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy
D014150:Antipsychotic Agents