title: A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.
authors.affiliation: Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: C I
authors.initials: CI
authors.lastname: Berul
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: P Y
authors.initials: PY
authors.lastname: Jay
authors.forename: H
authors.initials: H
authors.lastname: Wakimoto
authors.forename: P
authors.initials: P
authors.lastname: Douglas
authors.forename: N
authors.initials: N
authors.lastname: Yamasaki
authors.forename: T
authors.initials: T
authors.lastname: Kawamoto
authors.forename: J
authors.initials: J
authors.lastname: Gehrmann
authors.forename: C T
authors.initials: CT
authors.lastname: Maguire
authors.forename: M
authors.initials: M
authors.lastname: Schinke
authors.forename: C E
authors.initials: CE
authors.lastname: Seidman
authors.forename: J G
authors.initials: JG
authors.lastname: Seidman
authors.forename: Y
authors.initials: Y
authors.lastname: Kurachi
authors.forename: S
authors.initials: S
authors.lastname: Izumo
mesh_terms: D000200:Action Potentials; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000235:genetics* / Q000503:physiopathology; D004195:Disease Models, Animal; D004594:Electrophysiology; D006344:Heart Septal Defects, Atrial / Q000235:genetics* / Q000503:physiopathology; D006579:Heterozygote; D000072576:Homeobox Protein Nkx-2.5; D018398:Homeodomain Proteins / Q000235:genetics* / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D008817:Mice, Mutant Strains; D032383:Myocytes, Cardiac / Q000378:metabolism; D018408:Patch-Clamp Techniques; D011188:Potassium / Q000378:metabolism; D017180:Tachycardia, Ventricular / Q000235:genetics / Q000503:physiopathology; D014157:Transcription Factors; D029867:Xenopus Proteins
chemical_list: D000072576:Homeobox Protein Nkx-2.5; D018398:Homeodomain Proteins; C095552:NKX2-5 protein, human; C484469:Nkx2-5 protein, mouse; D014157:Transcription Factors; D029867:Xenopus Proteins; D011188:Potassium