title: [Clinical implications of impaired microcirculation and hemodynamics in acute respiratory viral infections and their pharmacological correction].
abstract: Microcirculation, hemocoagulation and blood viscosity were studied in 377 of 1033 inpatients with influenza and other acute respiratory viral infections. The new data show that it is feasible to improve the course, outcomes and results of the treatment. Microcirculation disorders persist throughout the disease, but in convalescence, intravascular alterations are leading. The microcirculatory changes manifest themselves with advanced erythrocyte aggregation, activation of vascular-platelet and plasmic links of hemostasis, and high blood viscosity at low shift velocities. In the presence of concomitant pathology (ischemic heart disease, hypertensive disease, diabetes mellitus) and development of complications, especially acute pneumonia, these disturbances are still greater and tend to increase to the period of decline of clinical and toxic manifestations. These patients should take acetylsalicylic acid (aspirin) as an antiaggregant and other medicines improving blood rheology.
authors.forename: B P
authors.initials: BP
authors.lastname: Bogomol'tsev
authors.forename: A V
authors.initials: AV
authors.lastname: Deviatkin
mesh_terms: D000208:Acute Disease; D000368:Aged; D001241:Aspirin / Q000627:therapeutic use*; D001783:Blood Flow Velocity / Q000502:physiology; D001809:Blood Viscosity / Q000502:physiology; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000175:diagnosis; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy / Q000821:virology
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin