title: Screening for familial colorectal cancer: the need for continuing education. A case report.
abstract: A 37 year old female patient was diagnosed with sigmoid colon cancer in our clinic five years ago (January 1998). The family history revealed three deaths due to colorectal cancer (maternal grandmother, mother's sister and patient's sister), and the patient's mother had been diagnosed with adenomatous polyps (endoscopically removed). Histopathological diagnosis was moderate / poorly differentiated adenocarcinoma. Resection of sigmoid colon was performed and adjuvant chemotherapy was carried out, with uneventful evolution. The patient was annually followed-up (colonoscopy, abdominal ultrasound, laboratory tests). The last admission was in January 2003. No recurrence or metastases were found. The patient's mother, who was admitted at the same time, had been diagnosed with urinary bladder tumor. Subjects with a personal or family history of colorectal cancer should routinely have a colonoscopy beginning from age 40 or earlier. It is important for such patients to be followed-up closely not only for recurrence or metastases, but also for detection and treatment of a second primary cancer at an early stage
authors.affiliation: 3rd Medical Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Adina
authors.initials: A
authors.lastname: Neagoe
authors.forename: Olimpia
authors.initials: O
authors.lastname: Chira
authors.forename: Monica
authors.initials: M
authors.lastname: Acalovschi
authors.forename: Dana
authors.initials: D
authors.lastname: Dumitra
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D010375:Pedigree; D012811:Sigmoid Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy