title: [Heart myxoma histogenesis in the light of its histological and ultrastructural features].
abstract: In 168 cases of heart myxoma histological and electron-microscopic examination have revealed signs of embryonal endothelium capable of vasoformation and glycoprotein and glycosaminoglycanes synthesis in myxoma cells. Neither differentiation of myxomas cells up to mature endotheliocytes no signs of malignant transformation was found. According to the authors, heart myxoma is a true benign dysontogenetic tumor originating from embryonal endothelium. The term myxoma does not reflect morphological entity of the tumor and the authors suggest to call it embryonal endocardial endothelioma.
authors.affiliation: City Clinical Hospital N 4, 115093, Moscow.
authors.forename: K A
authors.initials: KA
authors.lastname: Rogov
authors.forename: G F
authors.initials: GF
authors.lastname: Sheremet'eva
authors.forename: M A
authors.initials: MA
authors.lastname: Nechaenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D016591:Histocytological Preparation Techniques; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009232:Myxoma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure