title: Two cases of adult T-cell leukemia/lymphoma involving the terminal ileum.
abstract: We describe two cases of adult T-cell leukemia/lymphoma (ATLL) with terminal ileal involvement. The first case, a 71-year-old man with lymphoma subtype of ATLL, had a polypoid lesion in the terminal ileum, in addition to a duodenal mass. The second case, a 58-year-old woman with lymphoma subtype of ATLL, had an irregular ulcerative lesion in the terminal ileum and multiple ulcers throughout the stomach. Biopsies from these lesions revealed mucosal invasion of ATLL cells in each case. In the second case, combination chemotherapy was transiently effective, resulting in the disappearance of gastric and terminal ileal lesions. Prospective and careful examination of additional cases should further characterize the clinicopathological features of terminal ileal involvement in ATLL.
authors.affiliation: Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Ohnita
authors.forename: Hajime
authors.initials: H
authors.lastname: Isomoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Maeda
authors.forename: Toru
authors.initials: T
authors.lastname: Jubashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Nakamura
authors.forename: Yohei
authors.initials: Y
authors.lastname: Misuta
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Murase
authors.forename: Masao
authors.initials: M
authors.lastname: Tomonaga
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000368:Aged; D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000473:pathology*; D007078:Ileal Neoplasms / Q000473:pathology*; D007413:Intestinal Mucosa / Q000473:pathology; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged