title: A method for testing compressive properties of single proteoglycan aggregates.
abstract: This study presents a method for direct measurement of the compressive properties of single molecules of proteoglycan aggregate using a state-of-the-art laser tweezers/interferometer system previously developed to test the tensile properties of single molecules. A typical molecule of proteoglycan aggregate showed a highly non-linear resistance to compression after being compressed to about 25% of its original molecule length.
authors.affiliation: Sport Medicine Research Center, Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX 77030-2730, USA.
authors.forename: Xuhui
authors.initials: X
authors.lastname: Liu
authors.forename: Philip C
authors.initials: PC
authors.lastname: Noble
authors.forename: Zong-Ping
authors.initials: ZP
authors.lastname: Luo
mesh_terms: D019245:Compressive Strength; D007834:Lasers; D046911:Macromolecular Substances; D008857:Microscopy, Interference / Q000379:methods*; D011509:Proteoglycans / Q000737:chemistry* / Q000378:metabolism
chemical_list: D046911:Macromolecular Substances; D011509:Proteoglycans