Through-space delocalized water-soluble paracyclophane bichromophores: new fluorescent optical reporters.
Conjugated polymers and oligomers can serve as highly responsive fluorescent reporters for biosensor applications. However, their optical properties in aqueous media are highly dependent upon environmental conditions. The structure of the paracyclophane framework provides a platform for designing optical reporters that show little sensitivity to surfactants, and thus is well-suited for fluorescent assays. The permanent intramolecular delocalization through the paracyclophane core dominates intermolecular perturbations in spontaneously formed aggregates.
Hong
Janice W
JW
Departments of Chemistry and Materials, Institute for Polymers and Organic Solids, University of California, Santa Barbara, CA 93106, USA.
Benmansour
Hadjar
H
Bazan
Guillermo C
GC