Infection with human herpesvirus-8 and its correlation with hepatitis B virus and hepatitis C virus markers among rural populations in Cambodia.
Among 164 individuals in a rural population of Cambodia, antibodies to human herpesvirus-8 (HHV-8) were found among 56.6% of the women and 50.6% of the men. Seropositivity for HHV-8 tended to decrease with age (P < 0.001) and was not associated with exposure to hepatitis B virus (HBV) or HCV. Human herpesvirus-8, which shows a high rate of infection during childhood, does not seem to have the same pattern of transmission as HBV. This suggests very early acquisition of infection with HHV-8 in Cambodia.
Sarmati
Loredana
L
Department of Public Health, Tor Vergata University, Rome, Italy. sarmati@med.uniroma2.it
Andreoni
Massimo
M
Suligoi
Barbara
B
Bugarini
Roberto
R
Uccella
Ilaria
I
Pozio
Edoardo
E
Rezza
Giovanni
G
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D002160:Cambodia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D005260:Female; D006509:Hepatitis B / Q000150:complications / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000097:blood; D019288:Herpesvirus 8, Human / Q000276:immunology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012424:Rural Population; D012514:Sarcoma, Kaposi / Q000150:complications / Q000453:epidemiology*; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies