title: Early detection of secondary caries using quantitative, light-induced fluorescence.
abstract: The authors hypothesize that the arrestment and remineralization of these lesions could be improved if secondary caries could be detected and monitored at earlier stages. Traditional diagnostic techniques detect secondary caries when it is relatively advanced and when significant tissue has been lost. This in vitro study evaluated the Quantitative Light-induced Fluorescence (QLF) system for detecting and monitoring demineralization surrounding tooth-colored restorations. This investigation was divided into three studies. The first study evaluated QLF for the detection and measurement of chemically induced lesions surrounding resin composite restorations. The second study evaluated QLF for the detection of demineralization around different tooth-colored restorations (glass ionomer, resin composite, compomer and smart material) created in a microbial caries model. Finally, the third study tested whether QLF was effective at detecting early wall lesions adjacent to resin composite restorations. Data from Study 1 demonstrated the potential for QLF to detect very early secondary caries and to distinguish between the different stages of early demineralization. Study 2 confirmed the potential for QLF to detect early secondary caries created by cariogenic bacteria and concluded that the four types of materials differed in their ability to prevent secondary caries in this model, with the glass ionomer being the most effective and the non-fluoride releasing composite performing the worst, which allowed for the development of larger lesions. The results of Study 3 suggest a potential application of the QLF system to detect early wall lesions. Data from this investigation strongly suggest that QLF is a potentially viable technology to detect and monitor early secondary caries.
authors.affiliation: Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, IN, USA. cgonzale@iupui.edu
authors.forename: Carlos
authors.initials: C
authors.lastname: González-Cabezas
authors.forename: Margherita
authors.initials: M
authors.lastname: Fontana
authors.forename: Daniel
authors.initials: D
authors.lastname: Gomes-Moosbauer
authors.forename: George K
authors.initials: GK
authors.lastname: Stookey
mesh_terms: D000704:Analysis of Variance; D020770:Compomers; D003731:Dental Caries / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D003732:Dental Caries Activity Tests; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D005453:Fluorescence; D005899:Glass Ionomer Cements; D006801:Humans; D008027:Light; D008689:Methacrylates; D018613:Microscopy, Confocal; D012008:Recurrence; D012117:Resins, Synthetic; D018709:Statistics, Nonparametric
chemical_list: C409382:Ariston pHc; D020770:Compomers; C088486:Dyract; D005899:Glass Ionomer Cements; D008689:Methacrylates; C081144:Photac-Fil; D012117:Resins, Synthetic