[Experimental study of corpus cavernosal nerve evoked potential in diabetic rats].
OBJECTIVE
To observe the cavernosal nerve dysfunction of diabetic Sprague Dawley rats.


METHODS
Thirty-five Sprague-Dawley rats were divided randomly into diabetes model group(n = 25) and normal group(n = 10). Diabetes model was established by administration of streptozotocin (63 mg/kg) in single intraperitoneal dosing. Giving single wave stimulus, corpus cavernosal nerve was measured for its latent period of reaction and myopotential.


RESULTS
Compared with other groups, diabetic rats had longer reflection latent period(P < 0.01) and higher corpus cavernosum smooth muscle myopotential (P < 0.01).


CONCLUSIONS
The results indicate that corpus cavernosal nerve dysfunction may play an important role in the erectile dysfunction of diabetic rats.
Guo
Kai
K
Department of Internal Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
Wang
Xian-Hui
XH
Wang
Yi
Y
Wang
Zheng-Yi
ZY
Zhang
Fu-Wen
FW
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000209:etiology; D005071:Evoked Potentials; D008297:Male; D009569:Nitric Oxide / Q000502:physiology; D010413:Penis / Q000294:innervation*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013311:Streptozocin
D009569:Nitric Oxide; D013311:Streptozocin