[Opioid mechanism of regulation of the autonomic and motor functions in rabbits].
In rabbits, effects of s.c. administration of met-enkephaline (MET) and stimulation of hypothalamic nuclei upon vegetative and motor functions are similar and involve changes of the breathing rate, heart rate, and diminishing of the motor component of orienting responses. MET acts mainly upon cardiac parameters. Administration of naloxone eliminates the MET effect upon the vegetative and motor parameters. The role of opioid mechanism in regulation of the brain's visceral-motor function regulation, is emphasized.
Grigor'ian
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I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Acad. Sci., 194223, St. Petersburg, pr. M. Toreza, 44, Russia.
Sollertinskaia
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D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000378:metabolism / Q000502:physiology*; D017776:Autonomic Pathways / Q000502:physiology*; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004558:Electric Stimulation; D004562:Electrocardiography; D004744:Enkephalin, Methionine / Q000494:pharmacology / Q000502:physiology*; D006321:Heart / Q000294:innervation; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism / Q000502:physiology*; D011817:Rabbits
D009292:Narcotic Antagonists; D009270:Naloxone; D004744:Enkephalin, Methionine