Gyrate atrophy of the choroid: two cases.
BACKGROUND
Gyrate atrophy of the choroid (GA) is a rare, inherited choroidal dystrophy that results in progressive deterioration in peripheral and night vision. This is the first documentation of GA in Singapore.


METHODS
This report illustrates 2 cases of a sibling pair from a consanguineous union, presenting with the classical clinical features and biochemical abnormality of this condition.


RESULTS
One patient was treated with pyridoxine replacement and a low protein diet. However, his condition failed to improve. The other patient was left untreated.


CONCLUSIONS
Treatment was ineffective for the first patient. As yet, there is no proven treatment of GA.
How
A C
AC
Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751.
Koh
A H
AH
D000328:Adult; D005260:Female; D015799:Gyrate Atrophy / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008297:Male