[The role of ischemic heart disease risk factors in pathogenesis of cardiological syndrome X].
To specify lipid and carbohydrate metabolisms, coagulation and platelet hemostasis and their relationships with impairment of coronary circulation in patients with cardiological syndrome X (SX), we examined 204 SX patients and 31 controls. Compared to the controls, examinees with SX had signs of hyperinsulinemia, high levels of LDLP cholesterol, VLDLP cholesterol, atherogenic index, packed cell volume, fibrinogen and platelet aggregation. We found a positive correlation between the level of LDLP cholesterol, severity of hyperinsulinemia and maximal depression of ST wave in the course of bicycle exercise. There was no correlation between hemostasis parameters and the degree of ST depression.
Kostin
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Likhomanov
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D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005951:Glucose Tolerance Test; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D017566:Microvascular Angina / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology*; D012307:Risk Factors; D012720:Severity of Illness Index
D008078:Cholesterol, LDL