title: [Frequency of congenital anomalies at the Instituto Materno Infantil, Bogota, Colombia].
abstract: At the Instituto Materno Infantil (IMI) in Bogotá (Colombia), 5,686 births (5,597 live births and 89 stillbirths) were analyzed during two periods: from October, 1997, to April, 1998, and from July to November, 2000 (12 months). Congenital anomalies were detected in 4.4% of live newborn babies and in 7.8% of stillbirths. Major anomalies corresponded to 69% and mild anomalies to 31% (3% and 1.4% of all live births, respectively). The newborn babies with major anomalies, in comparison to the normal controls, had higher mortality at hospital discharge (p = 0.0001), lower average birth weight (p = 0.003), and family history of congenital anomalies (p = 0.0001). The only significant association for mild anomalies was with family history of congenital anomalies (p = 0.0001). The frequency of congenital anomalies was similar to that in other studies, although certain kinds of anomalies showed noticeable frequency differences. This may be a consequence of differences in record keeping or in detection methods.
authors.affiliation: Instituto de Genética, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.
authors.forename: Herbert
authors.initials: H
authors.lastname: García
authors.forename: Gustavo Andrés
authors.initials: GA
authors.lastname: Salguero
authors.forename: Jeffer
authors.initials: J
authors.lastname: Moreno
authors.forename: Clara
authors.initials: C
authors.lastname: Arteaga
authors.forename: Alejandro
authors.initials: A
authors.lastname: Giraldo
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D025063:Chromosome Disorders / Q000453:epidemiology*; D003105:Colombia / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy