Antimicrobial peptides from anurans skin secretions.
This article is an overview of antimicrobial peptides found in anurans skin secretions. These molecules constitute an initial barrier against microbial infections because of their activity against a large array of microorganisms. These peptides hold remarkable pharmaceutical and technological interest since they selectively kill microorganisms and are unlikely to induce resistance in pathogens. Also, outstanding synergism occurs when these peptides are combined with classic antibiotics and other antimicrobial peptides.
Nascimento
Anna Christina C
AC
Laboratório de Toxinologia, Departamento de Ciências Fisiológicas/IB, Universidade de Brasília, Brazil.
Fontes
Wagner
W
Sebben
Antonio
A
Castro
Mariana S
MS
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D001001:Anura / Q000378:metabolism*; D010455:Peptides; D012867:Skin / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010455:Peptides