Monocyte heterogeneity and innate immunity.
Peripheral monocyte heterogeneity is widely acknowledged in humans but until now comparable heterogeneity has not been characterized in mice. In this issue, Geissmann et al. use chemokine receptors to define two monocyte subsets and Serbina et al. highlight the importance of selective monocyte recruitment in the innate immune response to Listeria.
Taylor
Philip R
PR
Sir William Dunn School of Pathology, Oxford University, South Parks Road, OX1 3RE, Oxford, United Kingdom
Gordon
Siamon
S
D002465:Cell Movement; D003713:Dendritic Cells / Q000502:physiology; D006801:Humans; D007113:Immunity, Innate; D009000:Monocytes / Q000502:physiology*; D054390:Receptors, CCR2; D019707:Receptors, Chemokine / Q000502:physiology
C515334:CCR2 protein, human; D054390:Receptors, CCR2; D019707:Receptors, Chemokine