title: Clinical interpretation of the prostate biopsy.
abstract: Pathologic evaluation of the prostate biopsy provides the clinician with a wealth of information. Identifying needle biopsy parameters predictive of pathological stage and tumor volume at radical prostatectomy has become a major focus in the field of prostate pathology. From a review of the literature, the following factors are strongly predictive of extraprostatic disease; tumor involvement of greater than 25%, greater than two positive cores, cancer involvement greater than 3 mm, and perineural invasion. Such information could prove useful in patient counseling and identifying high-risk patients who may be good candidates for adjuvant therapy trials.
authors.affiliation: Department of Urology, University of Michigan Medical Center, 1500 Medical Center Drive, TC2916, Ann Arbor, MI, USA.
authors.forename: Javid
authors.initials: J
authors.lastname: Javidan
authors.forename: David P
authors.initials: DP
authors.lastname: Wood
mesh_terms: D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology*