title: Management of transfusion-related acute lung injury with extracorporeal cardiopulmonary support in a four-year-old child.
abstract: We report a case of successful management of transfusion-related acute lung injury (TRALI) with prolonged cardiopulmonary bypass support in a 4-yr-old patient undergoing elective cardiac surgery. TRALI was diagnosed clinically and immunologically by detection of reactive antibodies in a unit of fresh frozen plasma that had been administered to the patient. The aetiology and management of TRALI are briefly discussed and possible implications of this case for the management of TRALI are highlighted.
authors.affiliation: Regional Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK. smnouraei@yahoo.co.uk
authors.forename: S M
authors.initials: SM
authors.lastname: Nouraei
authors.forename: J P
authors.initials: JP
authors.lastname: Wallis
authors.forename: D
authors.initials: D
authors.lastname: Bolton
authors.forename: A
authors.initials: A
authors.lastname: Hasan
mesh_terms: D002315:Cardiopulmonary Bypass; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery; D006801:Humans; D011183:Postoperative Complications / Q000628:therapy*; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000628:therapy*; D065227:Transfusion Reaction