title: [Is there a circadian rhythm of interleukin 15 in humans?].
abstract: Nine healthy young men were studied under strict conditions for 48 h. The subjects were selected after a clinical examination and exploration of their rest-activity rhythm by actometry. The circadian rhythms of cortisol (peak at 8 AM) and melatonin (peak at 4 AM) were confirmed. The interleukin 15 (IL-15) was detected in the plasma samples with an Elisa kit (R&D System), but no reproducible variation could be observed during day 1 and day 2. In conclusion, in the conditions of our study, no rhythm was observed for IL-15. Our population will be completed with the inclusion of 6 additional subjects. These results will be specified.
authors.affiliation: Inserm unité 484, centre Jean-Perrin, 58, rue Montalembert, 63011, Clermont-Ferrand, France.
authors.forename: V
authors.initials: V
authors.lastname: Chevalier
authors.forename: F
authors.initials: F
authors.lastname: Gachon
authors.forename: F
authors.initials: F
authors.lastname: Kwiatkowski
authors.forename: J
authors.initials: J
authors.lastname: Papon
authors.forename: H
authors.initials: H
authors.lastname: Curé
authors.forename: M
authors.initials: M
authors.lastname: Doly
authors.forename: J-C
authors.initials: JC
authors.lastname: Madelmont
authors.forename: Ph
authors.initials: P
authors.lastname: Chollet
mesh_terms: D000293:Adolescent; D000328:Adult; D002940:Circadian Rhythm; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D019409:Interleukin-15 / Q000097:blood*; D008297:Male; D008550:Melatonin / Q000097:blood; D012016:Reference Values
chemical_list: D019409:Interleukin-15; D008550:Melatonin; D006854:Hydrocortisone