title: The effect of a liquid nutrition supplement on body composition and physical functioning in elderly people.
abstract: OBJECTIVE
  The elderly are at an increased risk of poor nutritional status which is mutually interacting with functional status. We evaluated the effects of a liquid nutrition supplement on anthropometric and functional indices in elderly people.
  
  
  METHODS
  Subjects (n=68; mean age=82+/-7 years) with body mass index <or=25 kg/m(2) received either a supplement or a placebo for 6 months. Anthropometric (body weight, bioelectrical impedance, calf circumference), biochemical (albumin, prealbumin), functional parameters (handgrip strength, timed 'up and go' test) and dietary intake were measured. Activities of daily living and Nottingham Health Profile (NHP) were assessed.
  
  
  RESULTS
  No compensation of energy intake occurred. After 6 months, the supplement group had gained more weight (+1.6 kg) than the placebo group (+0.3 kg) (P=0.03). No other significant changes in anthropometric, functional or blood parameters were seen. There was a significant improvement on the section 'sleep' of the NHP (mean change+/-SE=-0.38+/-0.19 for supplement vs 0.24+/-0.19 for placebo, P=0.03).
  
  
  CONCLUSIONS
  Dietary supplementation led to an increase in body weight and had a positive influence on sleep in elderly persons. Supplementation did not affect energy intake from regular meals and thus resulted in additional energy intake.
authors.affiliation: Department of Clinical Nutrition and Diets, Numico Research B V, Wageningen, The Netherlands.
authors.forename: W
authors.initials: W
authors.lastname: Wouters-Wesseling
authors.forename: C
authors.initials: C
authors.lastname: Van Hooijdonk
authors.forename: L
authors.initials: L
authors.lastname: Wagenaar
authors.forename: J
authors.initials: J
authors.lastname: Bindels
authors.forename: L
authors.initials: L
authors.lastname: de Groot
authors.forename: W
authors.initials: W
authors.lastname: Van Staveren
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D004311:Double-Blind Method; D002149:Energy Intake; D005260:Female; D005526:Food, Formulated; D018737:Hand Strength / Q000502:physiology; D006304:Health Status; D006801:Humans; D008297:Male; D009748:Nutrition Disorders / Q000097:blood / Q000517:prevention & control* / Q000628:therapy; D009752:Nutritional Status; D012709:Serum Albumin / Q000032:analysis; D012890:Sleep / Q000502:physiology*; D013649:Taste; D016896:Treatment Outcome
chemical_list: D012709:Serum Albumin