title: [The study of adaptation syndrome in mixed-infection of tick-borne encephalitis and borreliosis in children].
abstract: Twenty two children with mixed-infection of tick-borne encephalitis (TBE) and ixodic tick borreliosis (ITB) were studied. Blood hydrocortisone level was changed in 94.5% of the cases. The most significant activation of hydrocortisone secretion in combination with the most pronounced and prolonged general brain manifestations, was detected in infants. Blood hydrocortisone level correlated with clinical symptoms of combined TBE and ITB infections. Along with higher hydrocortisone level, down-regulation of production of antibodies both to B. burgdorferi and to TBE virus was specific for all children studied.
authors.forename: A V
authors.initials: AV
authors.lastname: Subbotin
authors.forename: T V
authors.initials: TV
authors.lastname: Poponnikova
authors.forename: S F
authors.initials: SF
authors.lastname: Zinchuk
mesh_terms: D000222:Adaptation, Physiological; D000293:Adolescent; D000311:Adrenal Glands / Q000378:metabolism / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004675:Encephalitis, Tick-Borne / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood* / Q000378:metabolism; D008193:Lyme Disease / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D008297:Male; D013577:Syndrome
chemical_list: D006854:Hydrocortisone