Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation.
Zinc is a common supplement and is widely available as a standard component of many over-the-counter products. A number of reports have identified an association between excessive zinc intake and severe cytopenia. We report a case of zinc-induced copper deficiency in a young adult to illustrate this under-recognized cause of anemia and neutropenia.
Irving
Julie A
JA
Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia and the University of British Columbia, Vancouver, BC.
Mattman
Andre
A
Lockitch
Gillian
G
Farrell
Kevin
K
Wadsworth
Louis D
LD
D000328:Adult; D000756:Anemia, Sideroblastic / Q000139:chemically induced*; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009503:Neutropenia / Q000139:chemically induced*; D004366:Nonprescription Drugs; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000188:drug therapy; D015032:Zinc / Q000009:adverse effects*
D004366:Nonprescription Drugs; D015032:Zinc