title: [Medication for premature ejaculation].
abstract: Drugs for the treatment of premature ejaculation (PE) are divided to two categories: oral drugs and local drugs. Oral drugs include antidepressive drugs, alpha-adrenoceptor blocking drugs, phosphodiesterase type V blocking drugs and Chinese herbal medicine. Local drugs include local surface drugs, intracavernosal injective drugs and local urethra drugs. Antidepressive drugs are extensively used, which have moderate efficacy, relatively more side effects and high recurrence rate; alpha-adrenoceptor blocking drugs are seldom used and are less effective than antidepressive drugs; phosphodiesterase type V blocking drugs like sildenafil have good efficacy and few side-effects and are worthy to be studied further. Local surface drugs like SS-Cream have good efficacy and few side-effects and are worthy to be applied and promoted; local urethral drugs like MUSE and Befar may become a new method to treat PE after being further studied. Medication for premature ejaculation shall be made specific and suitable as much as for each individual patient.
authors.affiliation: Department of Urology, People's Hospital of Hainan Province, Haikou, Hainan 570311, China.
authors.forename: Wei-Fu
authors.initials: WF
authors.lastname: Wang
authors.forename: De-Xin
authors.initials: DX
authors.lastname: Dong
authors.forename: Song
authors.initials: S
authors.lastname: Cen
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D004542:Ejaculation / Q000187:drug effects*; D006801:Humans; D008297:Male; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use
chemical_list: D000317:Adrenergic alpha-Antagonists; D000928:Antidepressive Agents; D004365:Drugs, Chinese Herbal; D010726:Phosphodiesterase Inhibitors