Rare association of xanthoma disseminatum with skeletal involvement.
A ten-year-old boy presented with a 2.5-year history of painful shoulder and hip joints, 1.5 years of yellow-brown papules and plaques on the face, flexures and trunk, and 6 months of polyuria and polydipsia. Skin biopsy revealed histological and immunohistochemical features typical of xanthoma disseminatum. Lytic bone lesions were seen in the femur and pelvis and sclerotic changes in the humerus on X-ray. Diabetes insipidus was also diagnosed
Khandpur
Sujay
S
Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. shaifalikhandpur@ath.net
Manchanda
Yashpal
Y
Sharma
Vinod K
VK
Singh
Manoj K
MK
Tandon
Nikhil
N
D001706:Biopsy; D001847:Bone Diseases / Q000150:complications / Q000175:diagnosis*; D002648:Child; D003919:Diabetes Insipidus / Q000150:complications / Q000175:diagnosis*; D005269:Femur / Q000000981:diagnostic imaging; D015616:Histiocytosis, Non-Langerhans-Cell / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging; D008297:Male; D011859:Radiography; D012867:Skin / Q000473:pathology