title: Genetic defenses against hypercholesterolemia.
authors.affiliation: McDermott Center for Human Growth and Development, Department of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
authors.forename: H H
authors.initials: HH
authors.lastname: Hobbs
authors.forename: G A
authors.initials: GA
authors.lastname: Graf
authors.forename: L
authors.initials: L
authors.lastname: Yu
authors.forename: K R
authors.initials: KR
authors.lastname: Wilund
authors.forename: J C
authors.initials: JC
authors.lastname: Cohen
mesh_terms: D000071018:ATP Binding Cassette Transporter, Subfamily G, Member 5; D000071019:ATP Binding Cassette Transporter, Subfamily G, Member 8; D018528:ATP-Binding Cassette Transporters / Q000235:genetics / Q000378:metabolism; D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport / Q000235:genetics / Q000378:metabolism; D001646:Bile / Q000378:metabolism; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics; D004705:Endocytosis; D005808:Genes, Recessive; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000235:genetics* / Q000378:metabolism*; D008074:Lipoproteins / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D011973:Receptors, LDL / Q000378:metabolism; D012855:Sitosterols / Q000097:blood; D013261:Sterols / Q000378:metabolism
chemical_list: C416945:ABCG5 protein, human; C416946:ABCG8 protein, human; D000071018:ATP Binding Cassette Transporter, Subfamily G, Member 5; D000071019:ATP Binding Cassette Transporter, Subfamily G, Member 8; D018528:ATP-Binding Cassette Transporters; D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport; C469745:LDLRAP1 protein, human; D008074:Lipoproteins; D011973:Receptors, LDL; D012855:Sitosterols; D013261:Sterols; C025473:gamma-sitosterol