Developments in drug delivery: implications for cancer care.
Changes in drug delivery as well as new drug development have impacted on cancer care in the past twenty years. Several modified release chemicals now have a role in cancer care, and new routes of drug delivery have been established as part of standard care. A range of strategies has been investigated to enhance anti-tumor selectivity of drugs including antibodies, liposomes and carrier molecules homing or activated in the environment of tumors. Fixed drug combinations are also used in cancer supportive care, and may find use in a range of settings.
Tattersall
Martin
M
University of Sydney, Blackburn Building D06, Sydney, NSW 2006, Australia. mtatt@med.usyd.edu.au
Clarke
Stephen
S
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D004333:Drug Administration Routes; D004337:Drug Carriers; D016503:Drug Delivery Systems / Q000379:methods* / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D010166:Palliative Care
D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers