title: [An epidemiological study on factors affecting serum thyroglobulin levels].
abstract: OBJECTIVE
  To investigate the effects of several factors affecting serum thyroglobulin (TG) levels among people aged 14 or more.
  
  
  METHODS
  We selected Panshan with median urinary iodine (MUI) 83.45 micro g/L as a deficient iodine intake community, Zhangwu with MUI 242.85 micro g/L as a sufficient iodine intake community and Huanghua with MUI 650.87 micro g/L as an excessive iodine intake community. Serum TG and thyroid stimulating hormone (TSH) were measured in 3,335 subjects whose thyroglobulin antibody (TGAb) were negative and thyroid volume were examined using B-ultrasound.
  
  
  RESULTS
  In the population with MUI of 80 - 650 micro g/L, serum TG levels presented a "V" curve. An elevated serum TG was found in both the communities with deficient iodine intake and excessive iodine intake. The same trend was shown in the groups with different levels of serum TSH. An elevated serum TG was found in both the groups of TSH < 0.3 mU/L and TSH > 4.8 mU/L. The serum TG levels was positively correlated with thyroid volume and was higher in female subjects than in male. An increased serum TG was found in subjects of aged 50 in the community with deficient iodine intake.
  
  
  CONCLUSIONS
  Serum TG level is affected by gender, amount of iodine intake, serum TSH level and thyroid volume.
authors.affiliation: Department of Endocrinology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China.
authors.forename: Chen-yang
authors.initials: CY
authors.lastname: Li
authors.forename: Hai-xia
authors.initials: HX
authors.lastname: Guan
authors.forename: Wei-ping
authors.initials: WP
authors.lastname: Teng
authors.forename: Zhong-yan
authors.initials: ZY
authors.lastname: Shan
authors.forename: Ying
authors.initials: Y
authors.lastname: Jin
authors.forename: Xiao-chun
authors.initials: XC
authors.lastname: Teng
authors.forename: Feng-nan
authors.initials: FN
authors.lastname: Hu
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Tian-shu
authors.initials: TS
authors.lastname: Gao
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Xiao-guang
authors.initials: XG
authors.lastname: Shi
authors.forename: Na
authors.initials: N
authors.lastname: Man
authors.forename: Ya-jie
authors.initials: YJ
authors.lastname: Tong
authors.forename: Xiu-juan
authors.initials: XJ
authors.lastname: Guo
authors.forename: Zhan-yi
authors.initials: ZY
authors.lastname: Wang
authors.forename: Shi-ming
authors.initials: SM
authors.lastname: Yang
authors.forename: Li
authors.initials: L
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007455:Iodine / Q000008:administration & dosage* / Q000172:deficiency / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D012424:Rural Population; D012737:Sex Factors; D013954:Thyroglobulin / Q000097:blood*; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D013972:Thyrotropin / Q000097:blood; D014463:Ultrasonography
chemical_list: D013972:Thyrotropin; D013954:Thyroglobulin; D007455:Iodine