[Dynamics of HBV-DNA level in acute hepatitis B].
OBJECTIVE
To verify the mechanism of the hepatitis B viral clearance using clinical data.


METHODS
Viral level and HBV marker in serum were analyzed in 12 patients with acute hepatitis B.


RESULTS
The clearance of hepatitis B virus occurred before the patients were hospitalized in 66.7% of patients. The viral level and the A value of HBsAg;HBeAg declined gradually during hospitalization.


CONCLUSIONS
In most of patients with acute hepatitis B in the study, the virus was cleared without destruction of infected cells.
Zhao
Hong
H
The First Hospital, Beijing University, Beijing 100034, China.
Cao
Jian-hua
JH
Tian
Geng-shan
GS
D000328:Adult; D004279:DNA, Viral / Q000097:blood*; D005260:Female; D006509:Hepatitis B / Q000821:virology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006512:Hepatitis B Core Antigens / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies
D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens