Molecular epidemiology of Newcastle disease in Republic of Korea.
Twenty-three strains of Newcastle disease virus (NDV) isolated between 1988 and 1999 in Republic of Korea were studied by partial nucleotide sequencing of fusion (F) gene and phylogenetic analysis. Most of Korean strains formed a distinctive cluster in genotype VI and they were genetically distant (4.0-8.7%) from other subtypes (a, b, c, d, and e), and termed provisionally VIf. Some Korean strains isolated in 1995 were grouped into genotype VIIa and they were closer to Taiwan strains than western Europe. The results suggest that the genotype VIf strains have been maintained by enzootic infections during the past decade, while genotype VIIa appears to be introduced more recently in Republic of Korea.
Kwon
Hyuk-Joon
HJ
Institute of iNtRON Biotechnology, Seongnam 462-120, Kyeonggi Province, South Korea. kwonhj01@hanmail.net
Cho
Sun-Hee
SH
Ahn
Young-Jin
YJ
Seo
Seung-Hee
SH
Choi
Kang-Seuk
KS
Kim
Sun-Joong
SJ
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens; D016000:Cluster Analysis; D007723:Korea / Q000453:epidemiology; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009521:Newcastle Disease / Q000453:epidemiology* / Q000821:virology; D009522:Newcastle disease virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D016415:Sequence Alignment; D014760:Viral Fusion Proteins / Q000235:genetics
D012367:RNA, Viral; D014760:Viral Fusion Proteins