Stiff person syndrome and anesthesia: case report.
This case report describes the successful perioperative management of a patient with a rare and disabling neurologic disorder, the stiff person syndrome. The patient had a delayed emergence despite apparent full reversal of neuromuscular blockade. We suggest an interaction between the GABAergic effects of baclofen and volatile anesthetics as a possible cause.
Bouw
Jans
J
*Departments of Anesthesiology and †Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Leendertse
Karin
K
Tijssen
Marina A J
MAJ
Dzoljic
Misa
M
D000758:Anesthesia / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009123:Muscle Hypotonia / Q000209:etiology; D016750:Stiff-Person Syndrome