title: Evaluation of chest radiography versus chest computed tomography in screening for pulmonary malignancy in advanced head and neck cancer.
abstract: OBJECTIVE
  To evaluate the role of chest radiography versus chest computed tomography (CT) in screening for pulmonary malignancy in advanced head and neck squamous cell carcinoma (HNSCC).
  
  
  METHODS
  Retrospective review of imaging.
  
  
  METHODS
  Head and neck cancer unit.
  
  
  METHODS
  Over a period of 1 year, 26 patients with advanced HNSCC (T3/T4) were screened for pulmonary malignancy with both chest radiography and chest CT prior to definitive therapy.
  
  
  METHODS
  Radiologic evidence of malignancy.
  
  
  RESULTS
  Twenty patients had a normal chest radiograph and a normal CT scan. Four patients had a normal chest radiograph but an abnormal CT scan. Three of these patients had a pulmonary malignancy and one had a suspicious lesion that resolved following surgery to the index tumour. Two patients had both an abnormal chest radiograph and CT scan. One of these had a pulmonary malignancy and one had a CT-guided biopsy of the chest lesion 4 weeks postoperatively, which was normal. Chest CT scanning therefore identified three chest malignancies that would have been missed by chest radiography alone.
  
  
  CONCLUSIONS
  Chest CT is an effective tool in screening for malignant pulmonary disease in patients with advanced head and neck cancer and should be used instead of chest radiography to avoid false-negative results.
authors.affiliation: Department of Otolaryngology/Head and Neck Surgery, The Radcliffe Infirmary, Oxford, UK.
authors.forename: Giles C
authors.initials: GC
authors.lastname: Warner
authors.forename: Graham J
authors.initials: GJ
authors.lastname: Cox
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000473:pathology*; D013902:Radiography, Thoracic; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed