Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster.
We have recently identified in Drosophila melanogaster a new gene encoding a nuclear protein, DIP1. Here we report the developmental expression and the finding that DIP1 subcellular localization is in the nucleus and at the nuclear periphery during interphase in embryos. Interestingly, in humans, DIP1 antibody identified signals in nuclei from cultured cells and reacted with a rough 30kDa protein in Western blotting experiments, demonstrating evolutionary conservation.
De Felice
Bruna
B
Department of Life Sciences, University of Naples II, Caserta, Italy. bruna.defelice@unina2.it
Wilson
Robert Roy
RR
Mondola
Paolo
P
Matrone
Gianfranco
G
Damiano
Simona
S
Garbi
Corrado
C
Nezi
Luigi
L
Su
Tin Tin
TT
D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D029721:Drosophila Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D016415:Sequence Alignment; D014157:Transcription Factors
C485815:CCNDBP1 protein, human; C410062:DISCO Interacting Protein 1, Drosophila; D029721:Drosophila Proteins; D009687:Nuclear Proteins; D014157:Transcription Factors