Olmsted syndrome: the clinical spectrum of mutilating palmoplantar keratoderma.
Olmsted syndrome is a rare variety of transgredient palmoplantar keratoderma with an undefined inheritance pattern. It starts in the neonatal period or in childhood and has a progressive and extremely disabling course. We report two new, unrelated patients with Olmsted syndrome, one with the early signs and symptoms of the disorder, the other showing the full-blown spectrum of the syndrome during a 30-year follow-up period.
Bergonse
Fabiane N
FN
Hospital das Clínicas, University of São Paulo, São Paulo, Brazil.
Rabello
Suzy M
SM
Barreto
Rodrigo L
RL
Romiti
Ricardo
R
Nico
Marcello Menta S
MM
Aoki
Valéria
V
Reis
Vitor Manoel S
VM
Rivitti
Evandro A
EA
D000671:Amputation, Surgical; D002675:Child, Preschool; D018450:Disease Progression; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013577:Syndrome