Antioxidative polyphenols from walnuts (Juglans regia L.).
Three hydrolyzable tannins, glansrins A-C, together with adenosine, adenine, and 13 known tannins were isolated from the n-BuOH extract of walnuts (the seeds of Juglans regia L.). Glansrins A-C were characterized as ellagitannins with a tergalloyl group, or related polyphenolic acyl group, based on spectral and chemical evidence. The 14 walnut polyphenols had superoxide dismutase (SOD)-like activity with EC(50) 21.4-190 microM and a remarkable radical scavenging effect against 1,1-diphenyl-2-picrylhydrazyl (DPPH) (EC(50) 0.34-4.72 microM).
Fukuda
Toshiyuki
T
Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan.
Ito
Hideyuki
H
Yoshida
Takashi
T
D001713:Biphenyl Compounds / Q000737:chemistry; D005419:Flavonoids / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry; D006834:Hydrazines / Q000737:chemistry; D031324:Juglans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010636:Phenols / Q000302:isolation & purification*; D010851:Picrates; D059808:Polyphenols; D012639:Seeds / Q000737:chemistry; D013482:Superoxide Dismutase / Q000737:chemistry
D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D006834:Hydrazines; D010636:Phenols; D010851:Picrates; D059808:Polyphenols; C004931:1,1-diphenyl-2-picrylhydrazyl; D013482:Superoxide Dismutase