title: Treatment and prognosis of early multiple gastric cancer.
abstract: OBJECTIVE
  Early gastric cancer (EGC) may have a 5-year survival rate of over 90% following surgery. Early multifocal gastric cancer (EMGC) accounts for between 8.3 and 17% of all EGCs. A multicenter retrospective study is reported of prevalence, characteristics, prognosis and type of resection for EMGC patients.
  
  
  METHODS
  333 patients with EGC were operated on, between January 1979 and December 1988, and followed to June 1996.
  
  
  RESULTS
  33 EGC patients had EMGC. There was no significant difference in clinico-pathological features between EGC and EMGC. 21 cases of EMGC underwent a subtotal gastrectomy and 12 underwent a total gastrectomy. Recurrences after subtotal gastrectomy were, respectively, 10 and 18% for EGC and EMGC patients (p=0.2). The cumulative 5 years specific survival rate for 298 EGC and 34 EMGC were 94 and 90%, respectively (p=0.9). Five-year survival rates after subtotal gastrectomy were 92 and 90% for EGC and EMGC patients, respectively (p=0.8).
  
  
  CONCLUSIONS
  EGC and EMGC had the same clinico-pathological features and prognosis. A careful follow up of the stomach remnant is essential.
authors.affiliation: Service Chirurgie A, Hôpital St Eloi, 34295, Montpellier, France. fborie@yahoo.com
authors.forename: F
authors.initials: F
authors.lastname: Borie
authors.forename: N
authors.initials: N
authors.lastname: Plaisant
authors.forename: B
authors.initials: B
authors.lastname: Millat
authors.forename: J M
authors.initials: JM
authors.lastname: Hay
authors.forename: P L
authors.initials: PL
authors.lastname: Fagniez
authors.forename: B
authors.initials: B
authors.lastname: De Saxce
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D015995:Prevalence; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome