title: Structural and evolutionary analysis of an orangutan foamy virus.
abstract: The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands. verschoor@bprc.nl
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Verschoor
authors.forename: Susan
authors.initials: S
authors.lastname: Langenhuijzen
authors.forename: Saskia
authors.initials: S
authors.lastname: van den Engel
authors.forename: Henk
authors.initials: H
authors.lastname: Niphuis
authors.forename: Kristin S
authors.initials: KS
authors.lastname: Warren
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Heeney
mesh_terms: D000818:Animals; D018420:Ape Diseases / Q000821:virology*; D001483:Base Sequence; D019143:Evolution, Molecular; D016679:Genome, Viral; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D011148:Pongo pygmaeus / Q000821:virology*; D012192:Retroviridae Infections / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA; D016092:Spumavirus / Q000737:chemistry / Q000235:genetics*