title: Photostabilizers for azadirachtin-A (a neem-based pesticide).
abstract: Photostability of azadirachtin-A (a neem based pesticide) has been studied without and with adding stabilizers such as ter. butyl-p-cresol, 8-hydroxy quinoline and ter. butyl hydroquinone as thin film on glass surface and on leaf surface under sunlight and UV light. Half-life of azadirachtin has been found to be 48 min and 3.98 days as thin film under UV light and sunlight and 2.47 days on leaf surface, respectively. 8-Hydroxy quinoline and ter. butyl hydroquinone have been found effective in controlling degradation of azadirachtin under both sunlight and UV light with half-life of 44.42 and 35.90 days under sunlight, and 55.80 and 48.50 h under UV light, respectively. Whereas ter. butyl-p-cresol has been found effective A only under sunlight. Significant decreases in antifeedant and insect growth regulatory activity against third instar larvae of Spodopterra litura has been observed with azadirachtin when exposed to sunlight and UV light. However, by the addition of above stabilizers, the biological activity of azadirachtin-A has been retained even after 24 h of irradiation under UV light and up to 30 days of exposure to sunlight.
authors.affiliation: Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, India.
authors.forename: Sapna
authors.initials: S
authors.lastname: Johnson
authors.forename: P
authors.initials: P
authors.lastname: Dureja
authors.forename: S
authors.initials: S
authors.lastname: Dhingra
mesh_terms: D000818:Animals; D001681:Biological Assay; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D006207:Half-Life; D007306:Insecticides / Q000737:chemistry* / Q000528:radiation effects; D007700:Kinetics; D007814:Larva; D036701:Limonins / Q000737:chemistry* / Q000528:radiation effects; D015125:Oxyquinoline / Q000494:pharmacology; D010777:Photochemistry; D010782:Photolysis; D018515:Plant Leaves; D012278:Ricinus; D018411:Spodoptera; D013472:Sunlight; D013499:Surface Properties; D014466:Ultraviolet Rays
chemical_list: D007306:Insecticides; D036701:Limonins; D015125:Oxyquinoline; C010329:azadirachtin