title: Adolescent self-poisoning: a cohort study of subsequent suicide and premature deaths.
abstract: Previous self-harm has been identified as a risk factor for subsequent suicide by adolescents. The objective of the study was to identify further risk factors for subsequent premature death and suicide in a population of adolescents presenting with self-poisoning. A longitudinal cohort design using data-linkage of consecutive adolescent patients presenting to the Hunter Area Toxicology Service, a regional toxicology service for Newcastle, Australia, with the National Death Index of the Australian Institute of Health and Welfare was used. A total of 441 adolescents aged 10 to 19 years presented with self-poisoning over 5 years from January 1991 to December 1995, with follow-up to March 2001. There were 14 deaths total, eight of which were likely suicides. There was a 22-fold increase in suicide rate for males and a 14-fold increase for females compared with age-normalized population rates. Adjusted hazard ratios (95% CI) forpremature death were male gender 3.77 (1.11-12.78), nonaffective psychotic disorders 16.3 (3.83-69.34) and the mental illnesses of childhood 6.12 (1.68-22.23). There was a similar pattern for suicide: Male gender, nonaffective psychotic disorders, and the mental illnesses of childhood confer greater risk for subsequent suicide or premature death in this population.
authors.affiliation: Dunedin School of Medicine, University of Otago, New Zealand. david.reith@stonebow.otago.ac.nz
authors.forename: David M
authors.initials: DM
authors.lastname: Reith
authors.forename: Ian
authors.initials: I
authors.lastname: Whyte
authors.forename: Greg
authors.initials: G
authors.lastname: Carter
authors.forename: Michelle
authors.initials: M
authors.lastname: McPherson
mesh_terms: D000293:Adolescent; D000328:Adult; D001315:Australia; D002423:Cause of Death; D002648:Child; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D011041:Poisoning / Q000523:psychology; D011618:Psychotic Disorders / Q000523:psychology*; D012307:Risk Factors; D012737:Sex Factors; D013405:Suicide / Q000523:psychology* / Q000706:statistics & numerical data; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data; D013997:Time Factors