title: Cell surface antigens of Mycoplasma species bovine group 7 bind to and activate plasminogen.
abstract: Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins.
authors.affiliation: Department of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.
authors.forename: Kylie
authors.initials: K
authors.lastname: Bower
authors.forename: Steven P
authors.initials: SP
authors.lastname: Djordjevic
authors.forename: Nicholas M
authors.initials: NM
authors.lastname: Andronicos
authors.forename: Marie
authors.initials: M
authors.lastname: Ranson
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000378:metabolism*; D000954:Antigens, Surface / Q000378:metabolism*; D002417:Cattle; D005341:Fibrinolysin / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D008024:Ligands; D009174:Mycoplasma / Q000145:classification / Q000276:immunology* / Q000472:pathogenicity / Q000502:physiology; D010958:Plasminogen / Q000378:metabolism*; D011485:Protein Binding; D011956:Receptors, Cell Surface / Q000276:immunology / Q000378:metabolism; D055293:Receptors, Urokinase Plasminogen Activator
chemical_list: D000942:Antigens, Bacterial; D000954:Antigens, Surface; D008024:Ligands; C524898:PLAUR protein, human; D011956:Receptors, Cell Surface; D055293:Receptors, Urokinase Plasminogen Activator; D010958:Plasminogen; D005341:Fibrinolysin