A young woman with ring-enhancing lesions.
A non-neutropenic patient receiving corticosteroids for systemic lupus erythematosus presented with fever, headache, and seizures. Ring enhancing lesions were found on computed tomography of the brain, and biopsy demonstrated Aspergillus fumigatis. Despite treatment, the patient died, and necropsy revealed Aspergillus endocarditis of the mitral and tricuspid valves.
Naidech
Andrew
A
Neurological Institute, Columbia University, New York, USA.
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004696:Endocarditis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008145:Louisiana; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D020953:Neuroaspergillosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D011859:Radiography; D016896:Treatment Outcome
D000935:Antifungal Agents