[Nervous system pathology and disruption of immunoreactivity in firefighters].
Fifty-eight firemen with encephalopathy were followed up. The development of nervous diseases was shown to be attended by immune homeostatic disorders, a characterizing decrease in the count of T lymphocytes bearing the markers CD4+, CD8+, a disproportion of immune-regulating subpopulations, a reduction in phagocytic neutrophils and their functional activity. There was an increase in IgA. Concurrently, there was an enhancement in the production of cytokines: IL-2, IL-6, IL-1 beta, TNF alpha.
Bodienkova
G M
GM
Ivanskaia
T I
TI
D005390:Fires / Q000517:prevention & control*; D006801:Humans; D016130:Immunophenotyping; D009422:Nervous System Diseases / Q000276:immunology / Q000473:pathology*; D009784:Occupational Diseases / Q000276:immunology / Q000473:pathology*; D016176:T-Lymphocyte Subsets