RhoB and the cellular response to farnesyltransferase inhibitors: the search for clues to cell death mechanisms.
Bernhard
Eric J
EJ
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. bernhard@mail.med.upenn.edu
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D015415:Biomarkers / Q000032:analysis*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D051231:Farnesyltranstransferase; D005347:Fibroblasts / Q000378:metabolism; D020869:Gene Expression Profiling; D051379:Mice; D018345:Mice, Knockout; D020411:Oligonucleotide Array Sequence Analysis; D020743:rhoB GTP-Binding Protein / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*
D000970:Antineoplastic Agents; D015415:Biomarkers; D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase; D020743:rhoB GTP-Binding Protein