title: Intestinal pseudo-obstruction in systemic lupus erythematosus.
abstract: In order to document intestinal pseudo-obstruction (IPO) as a recently recognized manifestation of systemic lupus erythematosus (SLE), we report the case or a woman with SLE who presented with IPO and we review 21 other previously reported cases from an English literature search. In 41% of the cases, IPO was the initial manifestation of their underlying lupus. The clinical and laboratory features were not significantly different from those reported in large series of patients with SLE, except for an apparent association with an urinary tract involvement (ureterohydronephrosis and interstitial cystitis). The pathogenic mechanism of this complication is not fully understood, but seems to be heterogeneous. IPO responded readily to high dose steroid therapy in all patients, but in some cases this complication evolved regardless of the underlying disease activity. A high level of awareness of this complication is needed to avoid unnecessary surgical intervention.
authors.affiliation: Rheumatology Unit, Clínica Delfos, Barcelona, Spain. 31577edd@comb.es
authors.forename: J
authors.initials: J
authors.lastname: Narváez
authors.forename: C
authors.initials: C
authors.lastname: Pérez-Vega
authors.forename: F J
authors.initials: FJ
authors.lastname: Castro-Bohorquez
authors.forename: A M
authors.initials: AM
authors.lastname: Garcia-Quintana
authors.forename: M
authors.initials: M
authors.lastname: Biosca
authors.forename: J
authors.initials: J
authors.lastname: Vilaseca-Momplet
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000209:etiology* / Q000503:physiopathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged