[Etiology of schizophrenia: review of genes-ambient interaction].
Schizophrenia is a disorder of extraordinary importance and complexity. Heterogeneity in the clinical presentation of schizophrenia is certain, which probably reflects heterogeneity in pathophysiology and etiology. Examination of various risk factors can give clues to the causes. Only genetic risk factors come anywhere near the effect size expected for a strong causal agent in schizophrenia. However, the existence of so many environmental risk factors cannot be ignored. Both psychosocial and biological environmental factors may interact with genetic vulnerability to increase the risk of schizophrenia.
Martínez
J A
JA
Unidad de Hospitalización Psiquiátrica, Hospital Virgen del Camino.
Cuesta
M J
MJ
Peralta
V
V