title: Gas chromatographic separation of saturated aliphatic hydrocarbon enantiomers on permethylated beta-cyclodextrin.
abstract: Enantiomers of chiral aliphatic hydrocarbons are generally difficult to separate because they lack functional groups to be derivatized in order to generate diastereomers. The systematic and quantitative separation of a series of branched hydrocarbon enantiomers using a chiral cyclodextrin stationary phase and a cryostat-controlled gas chromatograph is described. The use of a cryogenic system allows the improvement of separations for various chiral aliphatic hydrocarbons. The molecular cyclodextrin-based mechanism of the achieved enantiomeric separations is discussed briefly. Possible applications of this analytical technique are summarized, with special emphasis on the planned enantiomeric separation experiment on a cometary nucleus.
authors.affiliation: University of Bremen, Department of Physical Chemistry, Bremen, Germany.
authors.forename: Uwe J
authors.initials: UJ
authors.lastname: Meierhenrich
authors.forename: Mai-Julie
authors.initials: MJ
authors.lastname: Nguyen
authors.forename: Bernard
authors.initials: B
authors.lastname: Barbier
authors.forename: André
authors.initials: A
authors.lastname: Brack
authors.forename: Wolfram H P
authors.initials: WH
authors.lastname: Thiemann
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D003505:Cyclodextrins / Q000737:chemistry*; D006838:Hydrocarbons / Q000737:chemistry*; D008745:Methylation; D012833:Siloxanes / Q000737:chemistry; D013696:Temperature; D013997:Time Factors; D047392:beta-Cyclodextrins
chemical_list: D003505:Cyclodextrins; D006838:Hydrocarbons; D012833:Siloxanes; D047392:beta-Cyclodextrins; C031215:betadex