[Diagnosis and therapeutics of placental site trophoblastic tumor].
OBJECTIVE
In order to get better understanding of placental site trophoblastic tumor (PSTT), we have investigated 4 PSTT cases that diagnosed in our hospital and with literature reviews.


METHODS
We identified 4 patients of PSTT in our choriocarcinoma ward from Jan, 1985 to Dec, 2000 by retrospective analysis.


RESULTS
PSTT accounted for 3.1@1000 of all trophoblastic diseases, the ratio of PSTT to choriocarcinoma was 1:138. The average age was 31. Two cases were secondary to hydatidiform mole with paremetrial or pulmonary metastasis respectively. All cases received hysterectomy and multiple chemotherapy. With a follow-up of 29 to 84 months, all patients are survived up to now.


CONCLUSIONS
PSTT is a rare gestational trophoblastic tumor. Accurate pathological diagnosis is critical for proper treatment. The diagnosis and monitor are rather difficult because the beta-hCG are non-parallel to the growth and disappearance of the tumor. Operation plays an important role in its treatment, and multiple chemotherapy is helpful.
Deng
Shan
S
Department of Obstetric and Gynecology, PUMC Hospital, CAMS, PUMC, 100730, China. dengshan39@.hotmail.com
Yang
Xiu-yu
XY
D000328:Adult; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D018245:Trophoblastic Tumor, Placental Site / Q000175:diagnosis* / Q000601:surgery; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000601:surgery
D018997:Chorionic Gonadotropin, beta Subunit, Human