Clays as a host matrix in the synthesis of organic macrocycles.
A new approach for the synthesis of amide macrocycles, based on the use of organo-clay derivatives as controlling template, is proposed as an alternative to the rotaxane method. Dications of p-xylylene diamine inserted in the clay interlayer space act as molding pillars around which neutral diamine molecules are erected via hydrogen bonding and pi-pi interactions to form supramolecular arrays. Condensation of diamines in the supramolecular arrays with diacetyl dichlorides yields various tetramide macrocycles in good yields. Shape, aromaticity and dimensions of the reactants are factors affecting the condensation reaction.
Georgakilas
Vasilios
V
Institute of Material Science NCSR Demokritos Ag Paraskevi Attikis 15310 Athens, Greece.
Gournis
Dimitrios
D
Bourlinos
Athanasios B
AB
Karakassides
Michael A
MA
Petridis
Dimitrios
D