title: The sensory circumventricular organs of the mammalian brain.
abstract: The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the brain in which neurons are exposed to the chemical environment of the systemic circulation. Therefore they are ideally placed to monitor the changes in osmotic, ionic and hormonal composition of the blood. This book describes their. General structure and relationship to the cerebral ventricles Regional subdivisions Vasculature and barrier properties Neurons, glia and ependymal cells Receptors, neurotransmitters, neuropeptides and enzymes Neuroanatomical connections Functions.
authors.affiliation: Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Victoria, 3010, Australia. mmck@hfi.unimelb.edu.au
authors.forename: M J
authors.initials: MJ
authors.lastname: McKinley
authors.forename: R M
authors.initials: RM
authors.lastname: McAllen
authors.forename: P
authors.initials: P
authors.lastname: Davern
authors.forename: M E
authors.initials: ME
authors.lastname: Giles
authors.forename: J
authors.initials: J
authors.lastname: Penschow
authors.forename: N
authors.initials: N
authors.lastname: Sunn
authors.forename: A
authors.initials: A
authors.lastname: Uschakov
authors.forename: B J
authors.initials: BJ
authors.lastname: Oldfield
mesh_terms: D000818:Animals; D031608:Area Postrema / Q000033:anatomy & histology* / Q000502:physiology*; D002552:Cerebral Ventricles / Q000033:anatomy & histology / Q000502:physiology; D004805:Ependyma / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D008322:Mammals; D013356:Subfornical Organ / Q000033:anatomy & histology* / Q000502:physiology*