Health survey on workers and residents near the municipal waste and industrial waste incinerators in Korea.
Hazardous substances, such as polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) also have been detected in Municipal Solid Waste (MSW) and industrial waste incinerators in Korea. In this study, we estimated the exposure status of these hazardous substances and their heath effects in workers and residents near the MSW incinerators and residents near the industrial waste incinerators. We interviewed 13 workers and 16 residents from the area around the two MSW incinerators, and further 10 residents from the area around one industrial waste incinerator, which is suspected to emit higher hazardous substances. During the interview we collected information including sociodemographic information, personal habits, work history, detailed gynecologic and other medical history. Blood samples from 45 subjects were also collected for analysis of PCDDs and PCDFs, which were analyzed by HRGC-HRMS (High Resolution Gas Chromatography-High Resolution Mass Spectrometer). In addition to a questionnaire survey, urinary concentrations of 8-hydroxydeoxyguanosine (8-OH-dG) and malondialdehyde (MDA) were measured as oxidative injury biomarkers. Urinary concentrations of 8-OH-dG were determined by in vitro ELISA (JAICA, Fukuroi, Japan). MDA were determined by HPLC using adduct with TBA (thiobarbituric acid). The PCDD/F concentrations in residents from the area around industrial waste incinerator were higher than those in workers and residents from the area around MSW incinerator. The average toxic equivalency (TEQ) concentrations of PCDD/Fs in residents from the area around industrial waste incinerator were 53.4 pg I-TEQs/g lipid. The average TEQ concentrations of PCDD/Fs in workers and residents near MSW incinerator were 12.2 pg I-TEQs/g lipid. Estimated daily intake (EDI) of each person was calculated, and the EDI of all workers and residents near MSW incinerator were within the tolerable daily intake range. But for only 30% of 10 people near the industrial waste incinerator were the EDI within the tolerable daily intake range (1-4 pg I-TEQ/kg bw/day) suggested by WHO (1997). The oxidative stress of residents near the industrial waste incinerator was higher than that in workers and residents from the area around MSW incinerator. This oxidative stress may have been caused by hazardous substances, such as PCDD/Fs emitted by incinerators. The residents from the area around industrial waste incinerator were exposed to hazardous substances such as PCDD/ Fs. Proper protection strategies against these hazardous chemicals are needed.
Leem
Jong-Han
JH
Department of Occupational Medicine, Inha University, 7-206 Shin heung dong, Jung-gu, Incheon, Republic of Korea.
Hong
Yun-Cul
YC
Lee
Kwan-Hee
KH
Kwon
Ho-Jang
HJ
Chang
Yoon-Seok
YS
Jang
Jae-Yeon
JY
D001572:Benzofurans / Q000097:blood; D002947:Cities; D000072338:Dibenzofurans, Polychlorinated; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D017745:Incineration; D007220:Industrial Waste; D007407:Interviews as Topic; D007723:Korea / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects*; D018384:Oxidative Stress; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000097:blood; D011159:Population Surveillance
D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D007220:Industrial Waste; D000072317:Polychlorinated Dibenzodioxins