Influence of time period of cadmium intoxication on the concentrations of ascorbic acid selenium in certain tissues and blood serum of rats.
Ascorbic acid and selenium are important antioxidants for the reactive forms of oxygen. The purpose of these experiments was to determine the influence of various concentrations of cadmium on ascorbic acid and selenium concentrations in certain tissues of rats. The results showed that cadmium, added to rats' feed, influenced the concentration of ascorbic acid in blood serum and tested rats' tissues. Cadmium influenced the concentration of selenium in certain tissues as well. Furthermore, it has been demonstrated that ascorbic acid and selenium concentrations are dependent on the type of tissue tested as well as on the size of cadmium concentrations and length of the experiments.
Pasternak
Kazimierz
K
Department of General Chemistry, Medical University of Lublin.
Bielak
Ewa
E
D000818:Animals; D001205:Ascorbic Acid / Q000097:blood*; D002104:Cadmium / Q000493:pharmacokinetics / Q000633:toxicity; D002105:Cadmium Poisoning / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012643:Selenium / Q000097:blood*; D013997:Time Factors; D014018:Tissue Distribution
D002104:Cadmium; D012643:Selenium; D001205:Ascorbic Acid