[Steroids hormone and bone].
Bone is an active tissue in which the processes of remodeling are continuous to ensure normal bone integrity and strength. Steroids play an important role in regulating bone growth, development and remodeling. Glucocorticoids excess will induce bone damages especially osteoporosis. Otherwise, estrogen and androgen are bone protective steroids in both female and male. To develop a new selective steroid receptor modulator is one of the targets in future study to treat osteoporosis.
Meng
Xun-wu
XW
Department of Endocrinology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China.
Xia
Wei-bo
WB
D000328:Adult; D000728:Androgens / Q000502:physiology*; D001846:Bone Development; D016723:Bone Remodeling; D004967:Estrogens / Q000502:physiology; D005260:Female; D005938:Glucocorticoids / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010012:Osteogenesis; D010024:Osteoporosis / Q000517:prevention & control
D000728:Androgens; D004967:Estrogens; D005938:Glucocorticoids