title: Serum zinc in healthy Belgian children.
abstract: Many reports mention marginal zinc status in childhood. Information on serum zinc (Zn) in Belgian children since the last reports are old and feeding habits are changing. Four hundred fifty-seven healthy children (0-14 yr, 262 boys) had a venipuncture after an overnight fast during a vaccination campaign. Serum Zn, alpha-tocopherol (alpha-T), cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), apolipoprotein B (Apo B), Apo A, and malondialdehyde (MDA) were determinated. The median Zn value is lower in infants than in older children (respectively 11.6 micromol/L vs 12.8 micromol/L). The type of infant feeding does not influence the serum Zn concentrations (breast-feeding, adapted, hypoallergenic, soy, or thickened). No children had increased serum MDA concentrations and the value is not influenced by the Zn concentration. Children presenting higher serum Zn values also have significantly higher serum alpha-T levels. In infants, there is a significant positive correlation between serum Zn and cholesterol, LDL-C, and Apo B. In this apparently healthy population, no signs of abnormal in vivo peroxidation of fatty acids are observed, even in the children with low serum Zn. More sensitive methods for the detection of peroxidation are necessary for determination of in vivo effects of marginal trace element status.
authors.affiliation: Department of Paediatric Gastroenterology and Nutrition, UZ Ghent, Ghent, Belgium.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Van Biervliet
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Van Biervliet
authors.forename: Dirk
authors.initials: D
authors.lastname: Bernard
authors.forename: Raf
authors.initials: R
authors.lastname: Vercaemst
authors.forename: Vic
authors.initials: V
authors.lastname: Blaton
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001530:Belgium; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000032:analysis; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D015227:Lipid Peroxidation; D008297:Male; D012737:Sex Factors; D014801:Vitamin A / Q000032:analysis; D015032:Zinc / Q000097:blood*
chemical_list: D014801:Vitamin A; D002784:Cholesterol; D015032:Zinc