title: [Weekly cyclophosphamide pulse therapy combined with corticosteroids in the treatment of pemphigus].
abstract: OBJECTIVE
  To investigate the better regimen of combined cyclophosphamide pulse therapy with corticosteroids in the treatment of Pemphigus.
  
  
  METHODS
  Intravenous cyclophosphamide was given weekly in a dosage of 600 mg to those Pemphigus patients whose conditions couldn't be improved by corticosteroids (oral prednisone 1.2-1.5 mg/kg/d) alone.
  
  
  RESULTS
  Ten patients with Pemphigus received weekly cyclophosphamide therapy in addition to corticosteroid. Patients conditions improved quickly, without side effects.
  
  
  CONCLUSIONS
  Cyclophosphamide weekly pulse therapy combined with corticosteroids is a good regimen in the treatment of Pemphigus.
authors.affiliation: Department of Clinical Research, Institute of Dermatology, CAMS, PUMC, Nanjing 210042, China.
authors.forename: G Q
authors.initials: GQ
authors.lastname: Jia
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Chen
authors.forename: H L
authors.initials: HL
authors.lastname: Li
authors.forename: P G
authors.initials: PG
authors.lastname: Cui
authors.forename: W Y
authors.initials: WY
authors.lastname: Xu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage* / Q000009:adverse effects; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D007275:Injections, Intravenous; D010392:Pemphigus / Q000188:drug therapy*; D020551:Pulse Therapy, Drug; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide