[Antroduodenal motility and pH changes after partial gastrectomy including the pacemaker region of the dog's stomach].
BACKGROUND
Functional alterations of antroduodenal motility are not well defined at present. The gastric pacemaker is located at the greater curvature, next to the fundus.


OBJECTIVE
The aim was to evaluate the influence of the gastric pacemaker on the gastroduodenal motility in dogs.


METHODS
The study was designed in three steps and performed with 20 dogs: first, construction of a cervical esophagostomy to measure the antroduodenal motility and gastric pH-metry as validation step. The manometry was performed by means of a six point electronic manometry probe and both manometry and pH-metry were recorded during 4 hours. Second, the stomach's pacemaker region and gastric reservoir were resected by videolaparoscopy. Third, the antroduodenal motility and gastric pH-metry were measured again.


RESULTS
In the validation step, there was established a typical dogs' antroduodenal motility pattern, with a three-shaped interdigestive motility complex (IMC) (phases 1 to 3); the gastric pH-metry showed a baseline at pH 1,15. After partial gastric resection, overall there was an increase in contractions' frequency, an increase in phase 2 and a decrease in phase 3 participation on the IMC's. Regarding the gastric pH measurements, there was an increase in pH intervals 0-1 and 1-2 and a decrease in pH intervals 6-7; overall, there was a decrease in the stomach's pH and a decrease in the prandial time.


CONCLUSIONS
The resection of the stomach's pacemaker region and gastric reservoir correlated with alterations in antroduodenal motility, maintaining however the typical IMC pattern.
Nassif
Paulo Afonso Nunes
PA
Programa de Pós-graduação em Clínica Cirúrgica da Universidade Federal do Paraná em cooperação com o Instituto de Pesquisas Médicas da Faculdade Evangélica de medicina do Paraná e a Clínica Cirúrgica da Universidade de Wûrzburg - Almanha, Brasil.
Fuchs
Karl-Hermann
KH
Heimbucher
Johannes
J
Malafaia
Osvaldo
O
Czeczko
Nicolau Gregori
NG
Ribas Filho
Jurandir Marcondes
JM
Thiede
Arnulf
A
Dietz
Ulrich Andreas
UA
D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000502:physiology*; D005743:Gastrectomy / Q000379:methods*; D005745:Gastric Acidity Determination; D005769:Gastrointestinal Motility; D006863:Hydrogen-Ion Concentration; D008365:Manometry; D016065:Myoelectric Complex, Migrating; D010138:Pacemaker, Artificial; D011184:Postoperative Period