title: Synthesis of 2-aryl-oxazolo[4,5-c]quinoline-4(5H)-ones and 2-aryl-thiazolo[4,5-c]quinoline-4(5H)-ones.
abstract: [reaction: see text] Novel and highly efficient syntheses of oxazolo[4,5-c]quinoline-4(5H)-ones (1) and thiazolo[4,5-c]quinoline-4(5H)-ones (2) from ethyl 2-chlorooxazole-4-carboxylate (4) and ethyl 2-bromo-5-chlorothiazole-4-carboxylate (13), respectively, are described.
authors.affiliation: Neurogen Corporation, 35 Northeast Industrial Road, Branford, Connecticut 06405, USA. khodgetts@nrgn.com
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Hodgetts
authors.forename: Mark T
authors.initials: MT
authors.lastname: Kershaw