title: [Transient dysfunction of the retinal ganglion cells after laser in situ keratomileusis].
abstract: OBJECTIVE
  To evaluate the influence of high intraocular pressure(IOP) on the retinal ganglion cell function induced by suction during laser in situ keratomileusis(LASIK) using Frequency Doubling Technology(FDT).
  
  
  METHODS
  Twenty-seven eyes of 15 patients were studied. Threshold values of 19 targeted areas, mean deviation(MD), and pattern standard deviation (PSD) were measured before LASIK, and 2 hours, 1 day, and 1 week after LASIK. These parameters obtained by N-30 program of FDT were compared between before and after LASIK.
  
  
  RESULTS
  Significant decrease of MD and threshold value in all areas was recognized at 2 hours, but MD and threshold value in 6 of the 19 areas showed significant increase at 24 hours. Significant increase of PSD value at 2 hours was recognized. After 7 days, there were no significant differences in any parameters between before and after LASIK.
  
  
  CONCLUSIONS
  These results indicated that a transient dysfunction of the magnocellular pathway might be induced by high IOP during LASIK procedure.
authors.affiliation: Department of Ophthalmology, China-Japan Union Hospital, Ji Lin University, Japan.
authors.forename: Fan
authors.initials: F
authors.lastname: Wang
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Shoji
authors.forename: Kimiya
authors.initials: K
authors.lastname: Shimizu
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kawai
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nagayama
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kubo
authors.forename: Sayaka
authors.initials: S
authors.lastname: Nagata
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008297:Male; D008875:Middle Aged; D012165:Retinal Ganglion Cells / Q000502:physiology*