title: Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry.
abstract: The photocatalytic degradation of the organophosphorus insecticide diazinon in aqueous suspensions has been studied by using titanium dioxide as a photocatalyst. The degradation of the insecticide was a fast process and included the formation of several intermediates that were identified using GC/ion-trap mass spectrometry with EI or CI in positive and negative ionization mode and HPLC/electrospray-QqTOF mass spectrometry. Since primarily hydroxy derivatives were identified in these aqueous suspensions, the mechanism of degradation was probably based on hydroxyl radical attack. The initial oxidative pathways of the degradation of diazinon involved the substitution of sulfur by oxygen on the Pz.dbnd6;S bond, cleavage of the pyrimidine ester bond, and oxidation of the isopropyl group. Exact mass measurements of the derivatives allowed the elemental formula of the molecules to be determined confidently. Similarities to the metabolic pathways occurring in living organisms were observed.
authors.affiliation: General Chemical State Laboratory, Athens, Greece. gxk-pst@ath.forthnet.gr
authors.forename: Vasilis N
authors.initials: VN
authors.lastname: Kouloumbos
authors.forename: Despina F
authors.initials: DF
authors.lastname: Tsipi
authors.forename: Anastasia E
authors.initials: AE
authors.lastname: Hiskia
authors.forename: Dejan
authors.initials: D
authors.lastname: Nikolic
authors.forename: Richard B
authors.initials: RB
authors.lastname: van Breemen
mesh_terms: D002384:Catalysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003976:Diazinon / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007306:Insecticides / Q000737:chemistry*; D010782:Photolysis; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014025:Titanium / Q000737:chemistry*
chemical_list: D007306:Insecticides; C009495:titanium dioxide; D014025:Titanium; D003976:Diazinon