title: [Acute cupric sulfate intoxication: pathophysiology and therapy about a case report].
abstract: A case of acute copper sulfate intoxication is presented here, as an illustration of high toxic copper dose. A 38-years-old patient with a light mental deficit ingested half a glass of copper sulfate. This patient first suffered from nausea and vomiting, then an intravascular haemolysis occurred during the hospitalisation in our intensive care unit. The outcome was favourable under aetiologic and symptomatic treatment: administration of D-penicillamine as a copper antidote and packed red cell transfusion. The patient left the intensive care unit after 9 days. Acute copper intoxication is not an exceptional situation, with a potentially severe outcome.
authors.affiliation: Service d'anesthésie-réanimation, hôpital de l'Hôtel-Dieu, 1, place de l'Hôpital, 69288 Lyon cedex 02, France.
authors.forename: A
authors.initials: A
authors.lastname: Faure
authors.forename: L
authors.initials: L
authors.lastname: Mathon
authors.forename: J C
authors.initials: JC
authors.lastname: Poupelin
authors.forename: B
authors.initials: B
authors.lastname: Allaouchiche
authors.forename: D
authors.initials: D
authors.lastname: Chassard
mesh_terms: D000328:Adult; D002614:Chelating Agents / Q000627:therapeutic use; D019327:Copper Sulfate / Q000506:poisoning*; D017707:Erythrocyte Transfusion; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008607:Intellectual Disability; D008297:Male; D008581:Meningitis / Q000150:complications; D009325:Nausea / Q000139:chemically induced / Q000628:therapy; D010396:Penicillamine / Q000627:therapeutic use; D011041:Poisoning / Q000503:physiopathology / Q000628:therapy; D014839:Vomiting / Q000139:chemically induced / Q000628:therapy
chemical_list: D002614:Chelating Agents; D010396:Penicillamine; D019327:Copper Sulfate