Importance and pitfalls of molecular analysis to parasite epidemiology.
Molecular tools are increasingly being used to address questions about parasite epidemiology. Parasites represent a diverse group and they might not fit traditional population genetic models. Testing hypotheses depends equally on correct sampling, appropriate tool and/or marker choice, appropriate analysis and careful interpretation. All methods of analysis make assumptions which, if violated, make the results invalid. Some guidelines to avoid common pitfalls are offered here.
Constantine
Clare C
CC
Western Australian Biomedical Research Institute, Division of Health Science, School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch WA 6150, Australia. c.constantine@murdoch.edu.au
D000818:Animals; D005819:Genetic Markers; D005828:Genetics, Population; D017720:Molecular Epidemiology / Q000379:methods / Q000592:standards*; D010271:Parasites / Q000145:classification / Q000235:genetics*; D010272:Parasitic Diseases / Q000453:epidemiology* / Q000469:parasitology; D010802:Phylogeny
D005819:Genetic Markers