title: Double resection for patients with pancreatic cancer and a second primary renal cell cancer.
abstract: BACKGROUND
  Reports of synchronous or metachronous double kidney-pancreas cancers are very rare.
  
  
  METHODS
  We present 2 patients with renal cell carcinoma and synchronous (1 patient) or metachronous (1 patient) primary pancreatic ductal adenocarcinoma. The patients underwent resection for both cancer types with a worthwhile outcome.
  
  
  RESULTS
  The appearance of different primaries in an individual may indicate a genetic predisposition to different neoplasms. The study of double primary cancers is important because it might provide understanding of a shared genetic basis of different solid tumors.
  
  
  CONCLUSIONS
  The association between these two cancers demands more detailed epidemiological and molecular investigation. From a clinical viewpoint a resectional policy is recommended.
authors.affiliation: Department of Surgery, University of Liverpool, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: N
authors.initials: N
authors.lastname: Alexakis
authors.forename: L
authors.initials: L
authors.lastname: Bosonnet
authors.forename: S
authors.initials: S
authors.lastname: Connor
authors.forename: I
authors.initials: I
authors.lastname: Ellis
authors.forename: R
authors.initials: R
authors.lastname: Sutton
authors.forename: F
authors.initials: F
authors.lastname: Campbell
authors.forename: M
authors.initials: M
authors.lastname: Hughes
authors.forename: C
authors.initials: C
authors.lastname: Garvey
authors.forename: J P
authors.initials: JP
authors.lastname: Neoptolemos
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*