[Anneroth, Batsakis and Luna's modified classification as prognostic factor in patients with laryngeal carcinoma].
The cure rates for squamous cell carcinoma of the larynx have not improved over the past few decades. Despite the large number of therapeutic and histopathologic studies that have been performed, there are currently no clinical or morphologic markers available to predict outcome in patients with laryngeal carcinoma. The aim of the study was to exam tissues from 209 patients who were treated surgically because of advanced carcinoma of the larynx to create such a system. The examinations included routine histology and Anneroth, Batsakis and Luna's modified classification. The authors have analysed histologic parameters such as: cytoplasmic differentiation (kereatinization), nuclear polymorphism, number of mitoses per high-power field, mode and depth of invasion, plasmalymphocytic and eosinophil infiltration, to determine the potential usefulness of these factors in predicting recurrences and survival in patients with laryngeal cancer.
Starska
Katarzyna
K
Katedra Otolaryngologii i Klinika Laryngologii UM w Łodzi.
Kulig
Andrzej
A
Łukomski
Marek
M
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000145:classification* / Q000473:pathology* / Q000601:surgery; D004804:Eosinophils / Q000473:pathology; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000145:classification* / Q000473:pathology* / Q000601:surgery; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008940:Mitotic Index; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000032:analysis; D009364:Neoplasm Recurrence, Local / Q000145:classification / Q000473:pathology; D009687:Nuclear Proteins / Q000032:analysis; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis
D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D009687:Nuclear Proteins