title: Laser treatment of zone I prethreshold and stage 3 threshold retinopathy of prematurity.
abstract: OBJECTIVE
  To analyze the structural outcomes of zone I prethreshold and stage 3 threshold retinopathy of prematurity following laser ablation.
  
  
  METHODS
  This nonrandomized observational case series evaluated 71 eyes of 36 infants who weighed less than 1,250 g at birth. Infants were treated at either prethreshold or threshold severity. The structural outcomes were compared using Fisher's exact test.
  
  
  RESULTS
  The structural outcome was favorable in 96% and 80% of the prethreshold and threshold groups, respectively (P = .069). When an unfavorable outcome was defined as dragging of the temporal vessels, the difference was significant (P = .0257).
  
  
  CONCLUSIONS
  Early treatment of zone I disease may result in a better structural outcome.
authors.affiliation: Second Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
authors.forename: Zsuzsa
authors.initials: Z
authors.lastname: Récsán
authors.forename: Rita
authors.initials: R
authors.lastname: Vámos
authors.forename: György
authors.initials: G
authors.lastname: Salacz
mesh_terms: D001724:Birth Weight; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D017075:Laser Coagulation; D012178:Retinopathy of Prematurity / Q000145:classification / Q000601:surgery*