title: Patassium sensing oligonucleotide, PSO, based on DNA tetraplex formation.
abstract: Potassium Sensing Oligonucleotide, PSO, showing a high selectivity for K+ was synthesized by connecting 6-FAM and 6-TAMRA at the 5'- and 3'-termini of d(GGG TTA GGG TTA GGG TTA GGG), respectively. Circular dichroism (CD) spectra of PSO in the absence and presence of a various amount of KCl or NaCl revealed that PSO assumes an intramolecular or intermolecular antiparallel tetraplex structure in the presence of K+ and Na+, respectively.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka 812-8581, Japan.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Nojima
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ueyama
authors.forename: Makoto
authors.initials: M
authors.lastname: Takagi
authors.forename: Shigeori
authors.initials: S
authors.lastname: Takenaka
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*; D011188:Potassium / Q000378:metabolism*; D013050:Spectrometry, Fluorescence
chemical_list: D009841:Oligonucleotides; D004247:DNA; D011188:Potassium