[Clinical evaluation of local application of Merogel after endoscopic sinus surgery].
OBJECTIVE
To study the auxo-action of Merogel (hyaluronic acid) for operative cavity epithelialization after endoscopic sinus surgery (ESS).


METHODS
Sixteen patients (32 sides) were observed, in which all sinuses(maxillary, frontal, ethmoid and sphenoid) were operated on by ESS. For the purpose of control study, the left nasal side was used as Merogel group, and right side contrast group. The patients were followed-up for 12 weeks.


RESULTS
In Merogel group, the curative rate was 93.75%, improvement rate 6.25%, and average time of epithelialization was 3.4 weeks. In contrast group, the curative rate was 87.50%, improvement rate 12.50%, and average time of epithelialization was 8.3 weeks. It was distinct that in Merogel group, the epithelialization time was shorter than that in contrast group.


CONCLUSIONS
Merogel has auxo-action for operative cavity epithelialization after ESS.
Xu
Geng
G
Department of Otorhinolaryngology, Third Affiliated Hospital of Zhongshan University, Guangzhou 510630, China. entxgfess@163.com
Chen
He-xin
HX
Wen
Wei-ping
WP
Shi
Jian-bo
JB
Li
Yuan
Y
D000287:Administration, Topical; D000328:Adult; D003131:Combined Modality Therapy; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000187:drug effects*; D010256:Paranasal Sinuses / Q000601:surgery*; D012852:Sinusitis / Q000188:drug therapy / Q000601:surgery*
D006820:Hyaluronic Acid