title: A program for managing weight gain associated with atypical antipsychotics.
abstract: This study assessed the efficacy of a weight control program for patients taking atypical antipsychotics. Thirty-one patients with schizophrenia or schizoaffective disorder participated in a 12-week weight control program that incorporated nutrition, exercise, and behavioral interventions. Changes in patients' weight and in body mass index (BMI) were recorded and compared with those of 15 patients in a control group. The intervention group had a mean weight loss of 2.7 kg (six pounds) and a mean reduction of.98 BMI points, compared with a mean weight gain of 2.9 kg (6.4 pounds) and a mean gain of 1.2 BMI points in the control group. These data suggest that the intervention was effective in this group of patients. Professionals treating persons who are taking atypical antipsychotics should encourage them to engage in weight control activities.
authors.affiliation: Department of Psychiatry-Robert Wood Johnson Medical School and University Behavioral Health Care, University of Medicine and Dentistry of New Jersey, Piscataway, 08855, USA. vreelael@umdnj.edu
authors.forename: Betty
authors.initials: B
authors.lastname: Vreeland
authors.forename: Shula
authors.initials: S
authors.lastname: Minsky
authors.forename: Matthew
authors.initials: M
authors.lastname: Menza
authors.forename: Diane
authors.initials: D
authors.lastname: Rigassio Radler
authors.forename: Beatrix
authors.initials: B
authors.lastname: Roemheld-Hamm
authors.forename: Robert
authors.initials: R
authors.lastname: Stern
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001521:Behavior Therapy; D015992:Body Mass Index; D003631:Day Care, Medical; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000139:chemically induced / Q000628:therapy*; D011615:Psychotherapy, Group; D011618:Psychotic Disorders / Q000188:drug therapy*; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy*; D016896:Treatment Outcome; D014481:United States; D015430:Weight Gain / Q000187:drug effects*; D015431:Weight Loss
chemical_list: D014150:Antipsychotic Agents