A characteristic reactive hypoglycemia induced by rapid change of eating behavior in anorexia nervosa: a case report.
The relationship among reactive hypoglycemia, corresponding insulin metabolism, and eating behavior in anorexia nervosa (AN) has not been well documented.


METHODS
A 22-year-old woman with AN was admitted to Kagoshima University Hospital. An oral glucose tolerance test was performed with additional sampling at 15 minutes on the seventh hospital day when her daily caloric intake rapidly increased, reaching 2,000kcal perday.


RESULTS
An elevated level of insulin secretion (1,190pmol/L) was observed during the very early phase (15 minutes) after glucose load, whereas corresponding blood glucose elevations were not as high (1.2mmol/L). The patient experienced asymptomatic hypoglycemia (2.1mmol/L).


CONCLUSIONS
Our findings suggested that a rapid increase of energy intake might cause reactive hypoglycemia with characteristic insulin metabolism, that is, an elevated level of insulin secretion during the very early phase.
Yasuhara
Daisuke
D
Department of Psychosomatic Medicine, Kagoshima University Hospital, Kagoshima-city, Japan.
Deguchi
Daisuke
D
Tsutsui
Junko
J
Nagai
Nobuatsu
N
Nozoe
Shin-ichi
S
Naruo
Tetsuro
T
D000328:Adult; D000856:Anorexia Nervosa / Q000503:physiopathology* / Q000628:therapy; D002149:Energy Intake / Q000502:physiology*; D004734:Energy Metabolism / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007003:Hypoglycemia / Q000503:physiopathology*; D007328:Insulin / Q000097:blood*; D010343:Patient Admission; D012636:Secretory Rate; D015430:Weight Gain / Q000502:physiology
D007328:Insulin