Focal polymicrogyria, continuous spike-and-wave discharges during slow-wave sleep and Cohen syndrome: a case report.
Cohen syndrome is a rare genetic disorder consisting of truncal obesity, hypotonia, mental retardation, characteristic facial appearance and ocular anomalies. Other diagnostic clinical features include narrow hands and feet, low growth parameters, neutropenia and chorioretinal dystrophy. Here, we report an 18-year-old male with Cohen syndrome associated with focal polymicrogyria and continuous spike-and-wave discharges during slow-wave sleep.
Coppola
Giangennaro
G
Department of Psychiatry, Clinic of Child Neuropsychiatry, Child Neuropsychiatry, Audiophoniatry and Dermatovenereology, Second University of Naples, Via Pansini 5, 80131 Naples, Italy. giangennaro.coppola@unina2.it
Federico
Rosario R
RR
Epifanio
Giuseppina
G
Tagliente
Francesca
F
Bravaccio
Carmela
C
D000015:Abnormalities, Multiple / Q000473:pathology / Q000503:physiopathology*; D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D004569:Electroencephalography; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D008279:Magnetic Resonance Imaging; D008297:Male; D009216:Myopia / Q000235:genetics; D009765:Obesity / Q000235:genetics; D010291:Paresis / Q000209:etiology; D017286:Polysomnography; D011859:Radiography; D012640:Seizures / Q000150:complications*; D012890:Sleep / Q000502:physiology