Changes in blood biochemistry in mice during development of experimental depression.
Biochemical parameters of the plasma were studied in mice at different stages of the development of depression-like states in males after social defeats in 10 and 20 intermale confrontations (T10 and T20 victims, respectively). Glucose and cholesterol levels were increased in T10 victims in comparison with intact animals. In T20 victims the increase in glucose level was paralleled by an increase in total protein. T20 victims differed from T10 victims by lower catalase activity.
Avgustinovich
D F
DF
Sector of Neurogenetics of Social Behavior, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk.
Kovalenko
I L
IL
Sorokina
I V
IV
Tolstikova
T G
TG
D000378:Agonistic Behavior / Q000502:physiology*; D000818:Animals; D001774:Blood Chemical Analysis; D003863:Depression / Q000097:blood*; D006801:Humans; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D012930:Social Dominance; D013315:Stress, Psychological / Q000097:blood*