title: Papillary cystic type of acinic cell carcinoma of parotid: fine needle aspiration cytological features of a high grade variant with oncocytic metaplasia.
abstract: A 60-year-old female developed a right parotid swelling six months after surgery for intra-oral squamous cell carcinoma. Fine needle aspiration (FNA) cytological smears showed dissociated large and small pleomorphic tumour cells with abundant mitoses and oncocytic features. A cytological diagnosis of parotid acinic cell carcinoma (ACC) was made. Histological study of the subtotal parotidectomy specimen showed a papillary cystic variety of acinic cell carcinoma (ACC-PCV). FNA cytological features in this case of ACC-PCV differs from the two previously reported cases in that it showed prominent oncocytic and high grade features and absence of papillary pattern in the cytological smears. ACC-PCV is an uncommon tumour and knowledge of its varied FNA cytological features is important for the diagnosis of this neoplasm.
authors.affiliation: Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Gita
authors.initials: G
authors.lastname: Jayaram
authors.forename: Maizatul Asiah
authors.initials: MA
authors.lastname: Othman
authors.forename: Muthu
authors.initials: M
authors.lastname: Kumar
authors.forename: Gopala
authors.initials: G
authors.lastname: Krishnan
mesh_terms: D001707:Biopsy, Needle; D018267:Carcinoma, Acinar Cell / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006801:Humans; D008679:Metaplasia; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D024862:Oxyphil Cells / Q000473:pathology*; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome