A novel approach to the synthesis of oligodeoxyribonucleotide boranophosphates.
Deoxyribonucleoside 3'-boranophosphate derivatives including adenine, cytosine, guanine, and thymine bases were synthesized in good yields by the use of a new boranophosphorylation reaction. The reaction was found to be effective for the formation of internucleotidic boranophosphate linkages.
Wada
T
T
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Shimizu
M
M
Oka
N
N
Saigo
K
K
D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D007202:Indicators and Reagents; D008722:Methods; D015394:Molecular Structure; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D010766:Phosphorylation
D001896:Boron Compounds; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides