title: [Microflora of the large intestine in patients with connective tissue dysplasia].
abstract: The specific features of intestinal aerobic and anaerobic intestinal microflora in children with nondifferentiated connective tissue dysplasia were under study. A high rate of dysbiotic disturbances was noted in patients with connective tissue dysplasia in comparison with healthy persons. Profound quantitative and qualitative changes in the biocenosis of the intestine were detected in patients with the pathology of the gastrointestinal tract as well as that of the locomotor system. Changes in the species composition and the persistence properties of the intestinal microflora may serve as pathogenetic factors in the development of connective tissue dysplasia.
authors.affiliation: Institute of Cellular and Intracellular Symbiosis, Urals Branch, Rus. Acad. Sci., Orenburg, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Bukharin
authors.forename: O E
authors.initials: OE
authors.lastname: Chelpachenko
authors.forename: A V
authors.initials: AV
authors.lastname: Valyshev
authors.forename: N N
authors.initials: NN
authors.lastname: Elagina
authors.forename: N B
authors.initials: NB
authors.lastname: Perunova
authors.forename: E A
authors.initials: EA
authors.lastname: Mikhaĭlova
authors.forename: S V
authors.initials: SV
authors.lastname: Fomicheva
mesh_terms: D000293:Adolescent; D002648:Child; D003239:Connective Tissue Cells / Q000382:microbiology* / Q000473:pathology; D003240:Connective Tissue Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007420:Intestine, Large / Q000382:microbiology* / Q000473:pathology