A program for managing weight gain associated with atypical antipsychotics.
This study assessed the efficacy of a weight control program for patients taking atypical antipsychotics. Thirty-one patients with schizophrenia or schizoaffective disorder participated in a 12-week weight control program that incorporated nutrition, exercise, and behavioral interventions. Changes in patients' weight and in body mass index (BMI) were recorded and compared with those of 15 patients in a control group. The intervention group had a mean weight loss of 2.7 kg (six pounds) and a mean reduction of.98 BMI points, compared with a mean weight gain of 2.9 kg (6.4 pounds) and a mean gain of 1.2 BMI points in the control group. These data suggest that the intervention was effective in this group of patients. Professionals treating persons who are taking atypical antipsychotics should encourage them to engage in weight control activities.
Vreeland
Betty
B
Department of Psychiatry-Robert Wood Johnson Medical School and University Behavioral Health Care, University of Medicine and Dentistry of New Jersey, Piscataway, 08855, USA. vreelael@umdnj.edu
Minsky
Shula
S
Menza
Matthew
M
Rigassio Radler
Diane
D
Roemheld-Hamm
Beatrix
B
Stern
Robert
R
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001521:Behavior Therapy; D015992:Body Mass Index; D003631:Day Care, Medical; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000139:chemically induced / Q000628:therapy*; D011615:Psychotherapy, Group; D011618:Psychotic Disorders / Q000188:drug therapy*; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy*; D016896:Treatment Outcome; D014481:United States; D015430:Weight Gain / Q000187:drug effects*; D015431:Weight Loss
D014150:Antipsychotic Agents