Platelet substitutes in the management of thrombocytopenia.
A variety of agents can improve hemostasis and reduce blood loss caused or exacerbated by congenital or acquired defects in platelet number of function. This review discusses several available approaches for the practicing clinician to reduce bleeding (diffuse or localized) in this clinical setting.
Reid
Thomas J
TJ
Department of Blood Research, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910-7500, USA. thomas.reid@na.amedd.army.mil
Rentas
Frank J
FJ
Ketchum
Lloyd H
LH
D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects; D019468:Disease Management; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D013921:Thrombocytopenia / Q000097:blood / Q000188:drug therapy* / Q000628:therapy; D014014:Tissue Adhesives
D000933:Antifibrinolytic Agents; D006490:Hemostatics; D014014:Tissue Adhesives