Mesenteric venous thrombosis in a patient with prothrombin 20210A mutation and antithrombin III deficiency: challenges to conventional anticoagulation--a case report.
Mesenteric venous thrombosis presents as vague abdominal pain in patients with a medical or family history suggestive of a hypercoagulable state. Classic computed tomography findings will often confirm the diagnosis, and the presence of persistent abdominal pain or tenderness will determine the need for surgical intervention. Expeditious anticoagulation is the treatment of choice. This case demonstrates the CT findings for mesenteric venous thrombosis and discusses the challenges of anticoagulation in a patient with 2 hypercoagulable disorders.
Johnson
Chatt A
CA
Vascular Surgery Department, Walter Reed Army Medical Center, Washington, DC, USA.
Parker
Mary V
MV
Goff
James M
JM
D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D020152:Antithrombin III Deficiency / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007422:Intestines / Q000098:blood supply; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis* / Q000188:drug therapy; D008642:Mesenteric Veins / Q000000981:diagnostic imaging / Q000473:pathology; D009154:Mutation / Q000235:genetics; D011516:Prothrombin / Q000032:analysis* / Q000235:genetics; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin; D011516:Prothrombin