title: A randomized trial comparing 35Gy in ten fractions with 60Gy in 30 fractions of cerebral irradiation for glioblastoma multiforme and older patients with anaplastic astrocytoma.
abstract: A randomized prospective clinical trial was conducted to compare conventional high dose radiotherapy with hypofractionated, short course radiotherapy in poor prognosis patients with high grade glioma. The primary endpoint was overall survival.
authors.affiliation: Division of Radiation Oncology, Peter MacCallum Cancer Centre, Victoria, East Melbourne, Australia.
authors.forename: Claire
authors.initials: C
authors.lastname: Phillips
authors.forename: Michael
authors.initials: M
authors.lastname: Guiney
authors.forename: Jennifer
authors.initials: J
authors.lastname: Smith
authors.forename: Peter
authors.initials: P
authors.lastname: Hughes
authors.forename: Kailash
authors.initials: K
authors.lastname: Narayan
authors.forename: George
authors.initials: G
authors.lastname: Quong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001254:Astrocytoma / Q000401:mortality / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D019583:Dose Fractionation, Radiation; D005260:Female; D005909:Glioblastoma / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011788:Quality of Life; D015996:Survival Rate; D016896:Treatment Outcome