title: Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia.
abstract: Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia. The combination of both side effects is extremely rare. In this report, we describe a case of ciprofloxacin-induced interstitial nephritis and autoimmune hemolytic anemia. Hemolytic anemia improved after stopping the drug and initiation of steroid therapy. Unfortunately, acute interstitial nephritis was irreversible and the patient developed end-stage renal disease.
authors.affiliation: Division of Renal Medicine, Department of Internal Medicine, Tan Tock Seng Hospital, Singapore, Singapore. Salim_Lim@ttsh.com.sg
authors.forename: Salim
authors.initials: S
authors.lastname: Lim
authors.forename: Muhammad G
authors.initials: MG
authors.lastname: Alam
mesh_terms: D000208:Acute Disease; D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000139:chemically induced* / Q000201:enzymology; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002939:Ciprofloxacin / Q000009:adverse effects*; D005954:Glucosephosphate Dehydrogenase / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000201:enzymology
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D005954:Glucosephosphate Dehydrogenase