Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study.
Topical nitrogen mustard is an alkylating agent. Its efficacy in treating alopecia areata was reported in an uncontrolled study. We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 patients did not complete the trial.
Bernardo
Olga
O
University of British Columbia hair Research and Treatment Centre, Division of Dermatology, Vancouver General Hospital, Vancouver, Canada.
Tang
Liren
L
Lui
Harvey
H
Shapiro
Jerry
J
D000287:Administration, Topical; D000328:Adult; D000477:Alkylating Agents / Q000627:therapeutic use*; D000506:Alopecia Areata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000627:therapeutic use*; D008875:Middle Aged
D000477:Alkylating Agents; D008466:Mechlorethamine