title: Delayed femoral vein thrombosis after ultrasound-guided thrombin injection of a postcatheterization pseudoaneurysm.
abstract: Ultrasound-guided thrombin injection is a highly effective therapy for postcatheterization pseudoaneurysm. Despite a very low complication rate, a number of severe arterial thrombotic events have been reported. We present an unusual case of acute femoral vein thrombosis occurring several hours after successful treatment of femoral artery pseudoaneurysm by ultrasound-guided thrombin injection. Pathophysiologic mechanisms are discussed. This case highlights the potential hazards of instilling such a powerful thrombogenic substance in the immediate vicinity of other vascular structures.
authors.affiliation: CardioVascular Center, Cardiology, University Hospital, Rämistrasse 100, CH-8091 Zurich, Switzerland. david.kurz@usz.ch
authors.forename: David J
authors.initials: DJ
authors.lastname: Kurz
authors.forename: Karl-Peter
authors.initials: KP
authors.lastname: Jungius
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Lüscher
mesh_terms: D017541:Aneurysm, False / Q000188:drug therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects*; D005268:Femoral Vein; D006490:Hemostatics / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013917:Thrombin / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors; D020246:Venous Thrombosis / Q000209:etiology*
chemical_list: D006490:Hemostatics; D013917:Thrombin