Lipid and carbohydrate based adjuvant/carriers in immunology.
This review discusses various issues regarding vaccines; what are they and how they work, safety aspects, the role of adjuvants and carriers in vaccination, synthetic peptides as immunogens, and new technologies for vaccine development and delivery including the identification of novel adjuvants for mucosal vaccine delivery. There has been a recent increase of interest in the use of lipids and carbohydrates as adjuvants, and so a particular emphasis is placed on adjuvants derived from lipids or carbohydrates, or from both.
McGeary
Ross P
RP
School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Olive
Colleen
C
Toth
Istvan
I
D000276:Adjuvants, Immunologic / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000737:chemistry; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D014611:Vaccination; D014612:Vaccines / Q000737:chemistry* / Q000276:immunology*
D000276:Adjuvants, Immunologic; D002241:Carbohydrates; D008055:Lipids; D014612:Vaccines