Treatment of pustular psoriasis with granulocyte and monocyte adsorption apheresis.
We studied the efficacy of granulocyte and monocyte adsorption apheresis in 2 patients with pustular psoriasis, one localized, the other generalized. Treatment with granulocyte and monocyte adsorption apheresis resulted in remarkable clearing of the skin lesions, suggesting that this therapy is a valuable tool for treating patients with intractable skin diseases attributable to activated granulocytes. We present detailed descriptions of these patients and this novel therapy.
Kanekura
Takuro
T
Department of Dermatology, Kagoshima University, Japan. takurok@m2.kufm.kagoshima-u.ac.jp
Yoshii
Noriko
N
Yonezawa
Tomokazu
T
Kawabata
Hisashi
H
Saruwatari
Hiroshi
H
Kanzaki
Tamotsu
T
D005260:Female; D006098:Granulocytes; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D011565:Psoriasis / Q000473:pathology / Q000628:therapy*