title: Ovarian germ cell malignancy and human immunodeficiency virus (HIV) infection: a case report.
abstract: The occurrence of germ cell tumors in patients with human immunodeficiency virus (HIV) infection has not been previously reported. However, with the HIV pandemic in certain parts of the world, this association has become a reality. The approach to management as well as the role of adjuvant radiotherapy and chemotherapy is problematic as many of these therapies are toxic. The appropriate management of such tumors will remain elusive for sometime. The presentation, management, and outcome of ovarian endodermal sinus tumor in a HIV-infected patient is reported.
authors.affiliation: Department of Obstetrics and Gynaecology and MRC/UN Pregnancy Hypertension Research Unit, Nelson R Mandela School of Medicine, University of Natal, Durban, South Africa. moodleym29@nu.ac.za
authors.forename: M
authors.initials: M
authors.lastname: Moodley
authors.forename: J
authors.initials: J
authors.lastname: Moodley
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D018237:Germinoma / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D010052:Ovariectomy / Q000379:methods; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D016896:Treatment Outcome