title: Refinement and reduction in production of genetically modified mice.
mesh_terms: D000822:Animal Husbandry / Q000379:methods* / Q000592:standards; D000827:Animal Welfare / Q000592:standards; D000818:Animals; D005260:Female; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic