title: Effect of medical and biological factors on neurological manifestations of vertebral osteochondrosis in residents of the southern Altai Mountains.
abstract: We performed clinical and epidemiological study of 1508 residents living in the southern Altai Mountains and belonging to two subethnic groups (Telengite and Altai Kizhi). The incidence of neurological manifestations of vertebral osteochondrosis in people older than 17 years was 627.6 26.4%. The results show that genetic factors (hereditary polygenic predisposition) play a major role in the development of neurological manifestations of vertebral osteochondrosis. Premorbid state of the organism and diseases of various organs and systems promote the development of this neurological disorder.
authors.affiliation: Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
authors.forename: I R
authors.initials: IR
authors.lastname: Shmidt
authors.forename: V S
authors.initials: VS
authors.lastname: Sayapin
authors.forename: V Ch
authors.initials: VCh
authors.lastname: Van
authors.forename: L V
authors.initials: LV
authors.lastname: Van
authors.forename: V F
authors.initials: VF
authors.lastname: Malevik
authors.forename: M G
authors.initials: MG
authors.lastname: Zhestikova
authors.forename: O V
authors.initials: OV
authors.lastname: Podkhomutnikova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000886:Anthropometry; D005006:Ethnicity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology*; D010007:Osteochondritis / Q000150:complications* / Q000453:epidemiology* / Q000235:genetics; D011110:Polymorphism, Genetic; D012426:Russia / Q000453:epidemiology; D013131:Spine / Q000473:pathology*; D013223:Statistics as Topic