Pseudoductules in the rat liver in experimental adriamycin-induced nephrotic syndrome.
Pseudoductules proliferation in the liver is the condition observed in some liver diseases in human and experimental animals. It is observed in viral and alcoholic hepatitis, in hepatic cirrhosis and toxical liver damage. In that study pseudoductules were observed after i.p. single dose of adriamycin (5 mg/kg of body weight) administered to rats. Adriamycin given in this way is used to induce experimental nephrotic syndrome.
Pedrycz
Agnieszka
A
Department of Histology and Embryology, Medical University of Lublin.
Wieczorski
Marcin
M
Czerny
Krystyna
K
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000633:toxicity*; D001648:Bile Canaliculi / Q000187:drug effects* / Q000473:pathology; D002455:Cell Division / Q000187:drug effects*; D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology*; D004317:Doxorubicin / Q000493:pharmacokinetics / Q000633:toxicity*; D005260:Female; D007274:Injections, Intraperitoneal; D007677:Kidney Function Tests; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin