title: Determinants of human immunodeficiency virus (HIV) prevalence in homosexual and bisexual men screened for admission to a cohort study of HIV negatives in Belo Horizonte, Brazil: Project Horizonte.
abstract: Project Horizonte, an open cohort of homosexual and bisexual human immunodeficiency virus (HIV-1) negative men, is a component of the AIDS Vaccine Program, in Belo Horizonte, Minas Gerais, Brazil. The objective of this study was to compare volunteers testing HIV positive at cohort entry with a sample of those who tested HIV negative in order to identify risk factors for prevalent HIV infection, in a population being screened for enrollment at Project Horizonte. A nested case-control study was conducted. HIV positive volunteers at entry (cases) were matched by age and admission date to three HIV negative controls each. Selected variables used for the current analysis included demographic factors, sexual behavior and other risk factors for HIV infection. During the study period (1994-2001), among the 621 volunteers screened, 61 tested positive for HIV. Cases were matched to 183 HIV negative control subjects. After adjustments, the main risk factors associated with HIV infection were unprotected sex with an occasional partners, OR = 3.7 (CI 95% 1.3-10.6), receptive anal intercourse with an occasional partner, OR = 2.8 (95% CI 0.9-8.9) and belonging to the negro racial group, OR = 3.4 (CI 95% 1.1-11.9). These variables were associated with an increase in the risk of HIV infection among men who have sex with men at the screening for admission to an open HIV negative cohort.
authors.affiliation: Departamento de Parasitologia, Epidemiologia de Doenças Infecciosas e Parasitárias, Instituto de Ciências Biológicas, Belo Horizonte, Brasil. mcarneir@mono.icb.ufmg.br
authors.forename: Mariângela
authors.initials: M
authors.lastname: Carneiro
authors.forename: Fabíola Adriane
authors.initials: FA
authors.lastname: Cardoso
authors.forename: Marília
authors.initials: M
authors.lastname: Greco
authors.forename: Edson
authors.initials: E
authors.lastname: Oliveira
authors.forename: Júlio
authors.initials: J
authors.lastname: Andrade
authors.forename: Dirceu Bartolomeu
authors.initials: DB
authors.lastname: Greco
authors.forename: Carlos Maurício de Figueiredo
authors.initials: CM
authors.lastname: Antunes
mesh_terms: D000293:Adolescent; D000328:Adult; D001727:Bisexuality; D001938:Brazil / Q000453:epidemiology; D004812:Epidemiologic Methods; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D018023:HIV Seronegativity; D015497:HIV-1; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008875:Middle Aged