title: Warmed versus room temperature saline for laceration irrigation: a randomized clinical trial.
abstract: BACKGROUND
  Patient comfort is an important part of laceration repair.
  
  
  METHODS
  The study was a randomized single-blind cross-over trial in which each participant received 250 ml warmed and 250 ml room temperature saline irrigation in simple linear wounds after a local anesthetic was instilled. The solutions and the order of irrigation (warmed first versus second) were separately randomized with a washout period between. Investigators obtaining scores were blinded. Participants determined preferred solution, whether the solution was soothing, and which caused the most discomfort. Participants rated the pain of irrigation using separate Visual Analog Scale scores.
  
  
  RESULTS
  Thirty-eight patients were enrolled in the study. Significantly more preferred warmed to room temperature solutions (difference, 34%; 95% confidence interval, 5.7-63). A Wilcoxon signed-rank test for paired data showed no order effect (P = 0.49) or difference in pain measured according to the Visual Analog Scale (P = 0.082).
  
  
  CONCLUSIONS
  Warmed saline was more comfortable and soothing than room temperature saline as a wound irrigant among patients with linear lacerations.
authors.affiliation: Division of Emergency Medicine, University of California at Davis Medical Center, Sacramento, CA 95817, USA. aernst56@aol.com
authors.forename: Amy A
authors.initials: AA
authors.lastname: Ernst
authors.forename: Leslie
authors.initials: L
authors.lastname: Gershoff
authors.forename: Penny
authors.initials: P
authors.lastname: Miller
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Tilden
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Weiss
mesh_terms: D000328:Adult; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D022125:Lacerations / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D010147:Pain Measurement; D017060:Patient Satisfaction; D011446:Prospective Studies; D016037:Single-Blind Method; D012965:Sodium Chloride / Q000627:therapeutic use*; D013696:Temperature; D007507:Therapeutic Irrigation / Q000009:adverse effects*
chemical_list: D012965:Sodium Chloride