title: The urinary bladder: An extremely rare location of pediatric neuroblastoma.
abstract: Pediatric malignant tumors in the urinary bladder are rare with a high prevalence of rhabdomyosarcomas. A 15-month-old patient was referred to the authors' center because of a urinary bladder tumor. Imaging studies disclosed a solid pelvic mass in the dome of the bladder confirmed by a cystoscopy. Surprisingly, the biopsy done during this procedure confirmed a neuroblastoma with a favorable Shimada classification. This tumor had no bad prognostic factors. But, vessel compression and local infiltration led to delayed surgery, and neoadjuvant chemotherapy was initiated. After chemotherapy, a complete surgical resection was accomplished. Currently, this patient is in complete continuous remission. Only 5 other cases have been reported. Thus, urinary neuroblastoma seems to be a very rare pediatric tumor, but it should be considered in the differential diagnoses of urinary bladder tumor.
authors.affiliation: Pediatric Onco-Hematology Unit, CHRU Hautepierre, Strasbourg, France.
authors.forename: Natacha
authors.initials: N
authors.lastname: Entz-Werle
authors.forename: Luc
authors.initials: L
authors.lastname: Marcellin
authors.forename: François
authors.initials: F
authors.lastname: Becmeur
authors.forename: Didier
authors.initials: D
authors.lastname: Eyer
authors.forename: Annie
authors.initials: A
authors.lastname: Babin-Boilletot
authors.forename: Patrick
authors.initials: P
authors.lastname: Lutz
mesh_terms: D005260:Female; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009447:Neuroblastoma / Q000150:complications / Q000175:diagnosis*; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000175:diagnosis*