Nanocantilever signal transduction by electron transfer.
Microfabricated cantilever beams promise to bring about a revolution in the field of chemical, physical, and biological sensor development. The resonance frequency of a microfabricated cantilever shifts sensitively because of mass loading from molecular adsorption. The minimum detectable adsorbed mass on a cantilever sensor can be increased by orders of magnitude by changing the dimensions of the device; smaller and thicker cantilevers offer higher resonance frequency and therefore better mass detection sensitivity. Here we describe micromachined silicon cantilevers that are 0.5 to 4 microns in length, fabricated with the use of a focused ion beam (FIB). In addition, we demonstrate a technique for detection of the cantilever resonance frequency that is based on electron transfer.
Datskos
P G
PG
Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
Thundat
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T
D003460:Crystallization / Q000379:methods*; D004548:Elasticity; D004563:Electrochemistry / Q000379:methods; D004581:Electronics / Q000295:instrumentation* / Q000379:methods; D004583:Electrons; D004735:Energy Transfer; D004867:Equipment Design; D009038:Motion; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D012825:Silicon / Q000737:chemistry* / Q000528:radiation effects; D013314:Stress, Mechanical; D014159:Transducers; D014173:Transistors, Electronic
D012825:Silicon