title: Dura mater mitral and tricuspid bioprostheses: 30 years of follow-up.
abstract: OBJECTIVE
  The dura mater bioprosthesis was developed in the Department of Cardiopneumology of the Hospital das Clínicas of the University of São Paulo Medical School in 1971. Here, we present the clinical results of the dura mater bioprosthesis over 30 years of follow-up.
  
  
  METHODS
  We studied 70 consecutive patients who underwent mitral or tricuspid valve replacement with a dura mater bioprosthesis between January 1971 and August 1972.
  
  
  RESULTS
  The early mortality was 10% (7 patients). The follow-up was 87% complete (9 patients were lost to follow-up). Two patients were alive and asymptomatic 30 years after valve replacement; 33 patients underwent reoperations due to valve dysfunction, and 19 died during the follow-up period. At 30 years, the actuarial survival was 49.2 +/- 8.6%; freedom from rupture, 27.0 +/- 10.2%; freedom from calcification, 78.8 +/- 8.6%; and freedom from reoperation, 18.8 +/- 7.5%.
  
  
  CONCLUSIONS
  The dura mater bioprosthesis played an important role in the treatment of patients with mitral and tricuspid valve disease. The low rate of thromboembolism and the long period of follow-up without evidence of valve dysfunction, which occurred for several of our patients, are important characteristics of these bioprosthesis.
authors.affiliation: Department of Cardiopneumology of the Heart Institute, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil.
authors.forename: Luiz Boro
authors.initials: LB
authors.lastname: Puig
authors.forename: Carlos Manuel de Almeida
authors.initials: CM
authors.lastname: Brandão
authors.forename: Lauro
authors.initials: L
authors.lastname: Kawabe
authors.forename: Geraldo
authors.initials: G
authors.lastname: Verginelli
authors.forename: José Antonio Francchini
authors.initials: JA
authors.lastname: Ramires
authors.forename: Sérgio Almeida
authors.initials: SA
authors.lastname: de Oliveira
mesh_terms: D000293:Adolescent; D000328:Adult; D001705:Bioprosthesis; D001938:Brazil / Q000453:epidemiology; D004388:Dura Mater; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000592:standards*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000401:mortality / Q000601:surgery; D011474:Prosthesis Design; D014261:Tricuspid Valve; D014262:Tricuspid Valve Insufficiency / Q000401:mortality / Q000601:surgery