title: Neonatal pemphigus foliaceus.
abstract: The term "pemphigus" refers to a group of diseases that are characterized by the presence of cutaneous or mucosal blisters and erosions, and antiepidermal autoantibodies. There are several case reports of neonatal pemphigus vulgaris in the literature. Although pemphigus foliaceus antibodies have been shown to cross the placenta, to our knowledge, this is only the second reported case of neonatal pemphigus foliaceus. The proposed mechanism of disease transfer is the passive transfer of maternal IgG antibodies across the placenta.
authors.affiliation: Department of Dermatology, State University of New York Health Science Center at Brooklyn, Brooklyn, NY, USA.
authors.forename: Ranella
authors.initials: R
authors.lastname: Hirsch
authors.forename: Judy
authors.initials: J
authors.lastname: Anderson
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Weinberg
authors.forename: Penina
authors.initials: P
authors.lastname: Burnstein
authors.forename: Audrey
authors.initials: A
authors.lastname: Echt
authors.forename: Janet
authors.initials: J
authors.lastname: Fermin
authors.forename: Edward R
authors.initials: ER
authors.lastname: Heilman
authors.forename: Teresita A
authors.initials: TA
authors.lastname: Laude
mesh_terms: D000287:Administration, Topical; D001323:Autoantibodies / Q000276:immunology; D001707:Biopsy, Needle; D015820:Cadherins / Q000276:immunology*; D051183:Desmoglein 1; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D007150:Immunohistochemistry; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000276:immunology; D016712:Mupirocin / Q000008:administration & dosage; D010392:Pemphigus / Q000151:congenital* / Q000276:immunology / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D015820:Cadherins; D051183:Desmoglein 1; D016712:Mupirocin; D006854:Hydrocortisone