title: Acquired aqueductal stenosis in preterm infants: an indication for neuroendoscopic third ventriculostomy.
abstract: OBJECTIVE
  The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain the mechanisms of this stenosis.
  
  
  METHODS
  From January 1996 to June 2002, 1,046 premature infants were admitted to our institution. Thirty-six neonates suffered from grade 3 or 4 intraventricular hemorrhage (Papile grading), of whom 16 died. Twenty patients survived and a ventriculoperitoneal shunt was inserted in 7 infants. Four patients underwent a neuroendoscopic third ventriculostomy. Follow-up was carried out, twice a month during the first 2 months and subsequently twice a year.
  
  
  CONCLUSIONS
  In 2 children NTV was an effective treatment for hydrocephalus with an average follow-up of 29 months. The specific pattern concerning these patients is the long delay before obstructive hydrocephalus and the visualization of de novo obstruction with MRI. The biological explanation must be investigated.
authors.affiliation: Department of Pediatric Neurosurgery, Hôpital des Enfants, La Timone, 13385 Marseille Cedex 05, France. didier.scavarda@ap-hm.fr
authors.forename: D
authors.initials: D
authors.lastname: Scavarda
authors.forename: N
authors.initials: N
authors.lastname: Bednarek
authors.forename: F
authors.initials: F
authors.lastname: Litre
authors.forename: C
authors.initials: C
authors.lastname: Koch
authors.forename: G
authors.initials: G
authors.lastname: Lena
authors.forename: P
authors.initials: P
authors.lastname: Morville
authors.forename: P
authors.initials: P
authors.lastname: Rousseaux
mesh_terms: D002535:Cerebral Aqueduct / Q000002:abnormalities* / Q000601:surgery; D002552:Cerebral Ventricles; D002557:Cerebrospinal Fluid Shunts; D002675:Child, Preschool; D003251:Constriction, Pathologic / Q000503:physiopathology / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D020300:Intracranial Hemorrhages / Q000209:etiology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D007752:Obstetric Labor, Premature / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D011183:Postoperative Complications; D011247:Pregnancy; D014057:Tomography, X-Ray Computed; D014696:Ventriculostomy / Q000009:adverse effects / Q000379:methods