title: [IL-15 and autoimmune disease].
abstract: This review attempts to define the relationship between IL-15 and autoimmune disease (AID) from IL-15's tissue distribution, expression regulation and biologic function. Meanwhile, five IL-15 dysregulation-related AIDs and four IL-15/IL-15R-targeted AID therapies are described.
authors.affiliation: Medical Biotechnology Institute, Soochow University, Suzhou 215007, China.
authors.forename: Wen-xin
authors.initials: WX
authors.lastname: Li
authors.forename: Xue-guang
authors.initials: XG
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000378:metabolism*; D006801:Humans; D019409:Interleukin-15 / Q000378:metabolism*; D008180:Lupus Erythematosus, Systemic / Q000378:metabolism*; D009103:Multiple Sclerosis / Q000378:metabolism
chemical_list: D019409:Interleukin-15