Are patients with cancer receiving adequate treatment for thrombosis? Results from FRONTLINE.
The current practice of clinicians worldwide in the treatment of venous thromboembolism was assessed via responses to the FRONTLINE survey. Significant regional differences in practice were noted. Use of low-molecular-weight heparin was reported as the most common initial treatment for venous thromboembolism, although, in North America, unfractionated heparin was widely used to treat surgical cancer patients after a thrombotic episode. Oral anticoagulants were favoured for long-term treatment of venous thromboembolism, particularly in Western Europe and North America. Case study reports from the survey revealed that a substantial proportion of patients with cancer had been perceived to be at low risk of thrombosis, had consequently not received thromboprophylaxis and developed VTE.
Wong
John E-L
JE
Department of Haematology-Oncology, National University Hospital, 5 Lower Kent Ridge Road, Singapore. johnwong@nus.edu.sg <johnwong@nus.edu.sg>
D001291:Attitude of Health Personnel; D005060:Europe; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D019538:Health Care Surveys; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D009656:North America; D010820:Physicians; D020246:Venous Thrombosis / Q000209:etiology* / Q000517:prevention & control*
D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight