title: Ischaemic necrosis of the rectum and sigmoid colon complicating systemic lupus erythematosus.
abstract: The case of a 37-year-old Caucasian female with a history of systemic lupus erythematosus, admitted to hospital due to progressively worsening abdominal pain and arthralgia. During hospitalisation, signs of acute abdomen developed. Laparotomy revealed perforation of the rectum, accompanied by necrosis of the rectosigmoid. Histologic examination revealed vasculitis involving small- and medium-sized vessels. This case report emphasizes the point that colonic and especially rectal involvement from vasculitis, though unusual, may present with profound and possibly life-threatening manifestations and stresses the difficulties in clinical and histological differential diagnosis from other causes of systemic lupus erythematosus-associated abdominal pain.
authors.affiliation: Department of Pathology, Athens National and Kapodistrian University Medical Faculty, 75 Mikras Asias Str., Goudi, GR-115 27, Athens, Greece. alazaris@cc.uoa.gr
authors.forename: A Ch
authors.initials: ACh
authors.lastname: Lazaris
authors.forename: I S
authors.initials: IS
authors.lastname: Papanikolaou
authors.forename: G E
authors.initials: GE
authors.lastname: Theodoropoulos
authors.forename: K
authors.initials: K
authors.lastname: Petraki
authors.forename: P S
authors.initials: PS
authors.lastname: Davaris
mesh_terms: D000328:Adult; D012809:Colon, Sigmoid / Q000098:blood supply* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis*; D007511:Ischemia / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D009336:Necrosis; D012007:Rectum / Q000098:blood supply* / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology