title: 1H MR spectroscopy of brain tumours and masses.
abstract: Accurate diagnosis is essential for optimum management and treatment of patients with brain tumours. Proton magnetic resonance spectroscopy ((1)H MRS) provides information non-invasively on tumour biochemistry and has been shown to provide important additional information to that obtained by conventional radiology. We review the current status of (1)H MRS in classifying brain tumour type and grade, for monitoring response to therapy and progression to higher grade, and as a molecular imaging technique for determining tumour extent for treatment planning.
authors.affiliation: Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St George's Hospital Medical School, London, UK. f.howe@sghms.ac.uk
authors.forename: Franklyn A
authors.initials: FA
authors.lastname: Howe
authors.forename: Kirstie S
authors.initials: KS
authors.lastname: Opstad
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D001932:Brain Neoplasms / Q000145:classification* / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009367:Neoplasm Staging / Q000379:methods; D011522:Protons
chemical_list: D014408:Biomarkers, Tumor; D011522:Protons