title: Prognostic factors for the survival of surgically treated patients for non-small cell lung cancer.
abstract: The survival and outcome rates of 284 patients who underwent surgical treatment for non-small cell lung cancer were assessed retrospectively. Resectability rate was 94.1%, hospital mortality 3.9% (n = 11) and the mortality rates in patients who underwent pneumonectomy or lobectomy were 8.9% and 0.6%, respectively. The overall 5-year survival was 43.6%. Female gender, earlier stages of disease and a complete resection were strongly predictive for a long-term survival. Women in stage IA disease had a 5-year survival rate of 92.7%. The 5-year survival rate for patients in stages IIIA and N2 disease who underwent a complete resection was 21.9%, and 9% for those who did not undergo a complete resection. It is concluded that the best surgical results were observed in women who were operated on at an early stage of disease. A complete resection also contributed to a better outcome, even for patients in stage IIIA and N2 disease.
authors.affiliation: Department of Cardiothoracic Surgery, Orebro University Hospital, Orebro, Sweden. oswaldo.fernandes@orebroll.se
authors.forename: Oswaldo J C B
authors.initials: OJ
authors.lastname: Fernandes
authors.forename: Stig-Olof
authors.initials: SO
authors.lastname: Almgren
authors.forename: Lars
authors.initials: L
authors.lastname: Thaning
authors.forename: Derek
authors.initials: D
authors.lastname: Filbey
authors.forename: Martin
authors.initials: M
authors.lastname: Helsing
authors.forename: Mats
authors.initials: M
authors.lastname: Karlsson
authors.forename: Anders
authors.initials: A
authors.lastname: Magnusson
authors.forename: Domingos
authors.initials: D
authors.lastname: Souza
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018287:Carcinoma, Large Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012737:Sex Factors; D016019:Survival Analysis; D013548:Sweden / Q000453:epidemiology; D016896:Treatment Outcome