title: [Prognostication of hemodynamic efficacy of surgical correction of chronic coronary insufficiency based on stress test with nitroglycerine].
abstract: In our previous studies we demonstrated possibility of the use of stress echocardiography with sublingual administration of nitroglycerine for detection of viable myocardium. Basing on data about myocardial and cerebrovascular reserves obtained during nitroglycerine tests we created mathematical model for prediction of hemodynamic effectiveness of coronary bypass surgery. Stress echocardiography, Doppler echography of middle cerebral and internal carotid arteries with nitroglycerine were carried out in 80 patients with coronary artery disease before myocardial revascularization. Quantitative equivalent characterizing degree of myocardial reserve preservation in early postoperative period was used as basis for discrimination of patients into groups with positive and negative result of surgery, and coefficients and constants of discriminant function were calculated for these groups. According to results of clinical testing sensitivity, specificity and diagnostic effectiveness of the model were 76.9, 75 and 76%, respectively.
authors.forename: I N
authors.initials: IN
authors.lastname: Vorozhtsova
authors.forename: I L
authors.initials: IL
authors.lastname: Bukhovets
authors.forename: V V
authors.initials: VV
authors.lastname: Bezliak
authors.forename: V A
authors.initials: VA
authors.lastname: Dudko
mesh_terms: D002908:Chronic Disease; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D025401:Echocardiography, Stress / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D005996:Nitroglycerin; D011237:Predictive Value of Tests; D014665:Vasodilator Agents
chemical_list: D014665:Vasodilator Agents; D005996:Nitroglycerin