title: [Thromboembolic complication following temporary discontinuance of anticoagulant therapy in a patient with mechanical heart valve].
abstract: Patients with mechanical heart valves are treated with oral anticoagulant therapy in order to minimize the risk of thromboembolism. During invasive procedures it is recommended to temporarily discontinue the oral anticoagulant therapy and substitute with injections of low-molecular-weight heparin. We describe a case where a patient discontinued the oral anticoagulant therapy and had no substitution with low-molecular-weight heparin. The patient had an embolism to the coronary arteries causing progressive heart failure, and the patient was subsequently heart transplanted.
authors.affiliation: Arhus Universitetshospital, Skejby Sygehus, Hjerte-, Lunge-, Karkirurgisk Afdeling T og Hjertemedicinsk Afdeling B, og Aarhus Universitet, Institut for Eksperimentel Klinisk Forskning. t.d.christensen@iekf.au.dk
authors.forename: Thomas Decker
authors.initials: TD
authors.lastname: Christensen
authors.forename: Kim C
authors.initials: KC
authors.lastname: Houlind
authors.forename: Kaj Erik
authors.initials: KE
authors.lastname: Klaaborg
authors.forename: Hans-Henrik O
authors.initials: HH
authors.lastname: Kure
authors.forename: Hans
authors.initials: H
authors.lastname: Eiskjaer
authors.forename: John Michael
authors.initials: JM
authors.lastname: Hasenkam
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D001022:Aortic Valve Insufficiency / Q000601:surgery; D003328:Coronary Thrombosis / Q000139:chemically induced* / Q000601:surgery; D016027:Heart Transplantation; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D013375:Substance Withdrawal Syndrome / Q000209:etiology*; D013923:Thromboembolism / Q000139:chemically induced* / Q000601:surgery; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014859:Warfarin