[Twenty-four hour blood pressure rhythm in patients with hypertension and ischemic heart disease].
OBJECTIVE
To elucidate relationship between presence of ischemic heart disease and 24-hour blood pressure (BP) profile.


METHODS
Twenty four hour BP index characterizing degree of nocturnal blood pressure fall was measured in patients with hypertension without coronary heart disease (n=65, group 1), with hypertension and effort angina (n=35, group 2), with effort angina and normal BP (n=25, group 3).


RESULTS
Values of 24-hour BP systolic and diastolic index were in group 1 12.7+/-1.3 and 16.0+/-1.1%, respectively, in group 2 5.8+/-2.4 and 7.4+/-3.6%, respectively, in group 3, 6.0+/-2.2 and 6.0+/-3.0%, respectively (p<0.05, groups 2 and 3 vs group 1).


CONCLUSIONS
Decreased nocturnal BP lowering could be a compensatory reaction aimed at maintenance of adequate blood flow through stenosed coronary vessels.
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D000328:Adult; D000787:Angina Pectoris / Q000503:physiopathology; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology*; D013997:Time Factors