[Mammography screening--neglected aspects of radiation risks].
It is generally assumed that the radiation risk from mass screening for breast cancer may be neglected. This is questionable in view of the high biological effectiveness of low energy X-rays used in radiography of the breasts. The hormone replacement therapy for elderly women must be considered as a further cause for unexpected high rates of radiation-induced breast cancer cases. Each normal population of women, moreover, contains a very radiosensitive subgroup: the women bearing a mutation of the gene BRCA 1 or BRCA 2. In these, repeated X-ray use must be definitely avoided.
Kuni
H
H
Med. Zentrum für Radiologie, Universitätsklinikum Lahnberge, Marburg. horst@kuni.org
Schmitz-Feuerhake
I
I
Dieckmann
H
H
D000328:Adult; D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology* / Q000235:genetics; D002986:Clinical Trials as Topic; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D008327:Mammography / Q000009:adverse effects*; D008875:Middle Aged; D009154:Mutation; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011829:Radiation Dosage; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors