title: Structural biology. Breaching the barrier.
authors.affiliation: Institut für Molekularbiologie und Biophysik, Eidgenössische Technische Hochschule Zürich, Zürich CH-8093, Switzerland.
authors.forename: Kaspar P
authors.initials: KP
authors.lastname: Locher
authors.forename: Randal B
authors.initials: RB
authors.lastname: Bass
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Rees
mesh_terms: D001665:Binding Sites; D001692:Biological Transport; D002462:Cell Membrane / Q000201:enzymology; D018360:Crystallography, X-Ray; D004926:Escherichia coli / Q000737:chemistry / Q000201:enzymology; D029968:Escherichia coli Proteins / Q000737:chemistry* / Q000378:metabolism; D005994:Glycerophosphates / Q000378:metabolism; D007785:Lactose / Q000378:metabolism; D026901:Membrane Transport Proteins / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D009004:Monosaccharide Transport Proteins; D010710:Phosphates / Q000378:metabolism; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D027981:Symporters
chemical_list: D029968:Escherichia coli Proteins; C488962:GlpT protein, E coli; D005994:Glycerophosphates; C050221:LacY protein, E coli; D026901:Membrane Transport Proteins; D009004:Monosaccharide Transport Proteins; D010710:Phosphates; D027981:Symporters; C021499:lactose permease; C029620:alpha-glycerophosphoric acid; D007785:Lactose