Exposure to animals and selected risk factors among Canadian farm residents with Hodgkin's disease, multiple myeloma, or soft tissue sarcoma.
Exposures to farm animals has been associated with certain rare cancers. Simultaneously, using the same methodology and control group, we conducted a six-province incident, population-based study of Hodgkin's disease (HD), multiple myeloma (MM), and soft tissue sarcoma (STS). Farm residence or work was reported by 38% (n = 119) of HD, 45% (n = 178) of MM, 43% (n = 156) of STS cases and 45% (n = 673) of controls. We conducted conditional logistic regression analyses and report odds ratios (OR(adj)) and 95% confidence intervals. After adjustment for covariates, exposure to farm animals had minimal effect on risk. The independent risk factors after adjustment for covariates were a family history of cancer (MM, STS), occupational uranium exposure (HD), professional driving (MM), and personal previous cancer (MM) or shingles (HD, MM).
Pahwa
Punam
P
Institute of Agricultural Rural and Environmental Health, Saskatchewan Cancer Agency, Saskatoon SK S7N 0W8, Canada.
McDuffie
Helen H
HH
Dosman
James A
JA
Robson
Diane
D
McLaughlin
John R
JR
Spinelli
John J
JJ
Fincham
Shirley
S
D000293:Adolescent; D000328:Adult; D000382:Agricultural Workers' Diseases / Q000139:chemically induced / Q000453:epidemiology*; D000822:Animal Husbandry; D000818:Animals; D000829:Animals, Domestic; D002170:Canada / Q000453:epidemiology; D016022:Case-Control Studies; D003625:Data Collection; D006540:Herbicides / Q000506:poisoning; D006689:Hodgkin Disease / Q000139:chemically induced / Q000453:epidemiology*; D006801:Humans; D009101:Multiple Myeloma / Q000139:chemically induced / Q000453:epidemiology*; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D010575:Pesticides / Q000506:poisoning; D012307:Risk Factors; D012509:Sarcoma / Q000139:chemically induced / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D000078329:Workforce
D006540:Herbicides; D010575:Pesticides