title: Successful treatment of primary non-Hodgkin's lymphoma of the vagina with chemotherapy.
abstract: BACKGROUND
  The vagina as a primary site of malignant lymphoma in woman is extremely rare.
  
  
  METHODS
  We report here a 30-year-old patient with a primary vaginal non-Hodgkin's lymphoma stage IEA, follicular large cell of B lineage, with an excellent response to cytotoxic chemotherapy (CHOP) and event-free survival of 28 months.
  
  
  CONCLUSIONS
  Primary involvement of the vagina can be successfully treated by pelvic irradiation, but in young women chemotherapy should be considered to preserve fertility, as well as quality of life.
authors.affiliation: Department of Medical Oncology, Hacettepe University Oncology Institute, 06100 Sihhiye, Ankara, Turkey. hengin@hacettepe.edu.tr
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Engin
authors.forename: Alev
authors.initials: A
authors.lastname: Türker
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Abali
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Uner
authors.forename: Serdar
authors.initials: S
authors.lastname: Günalp
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008224:Lymphoma, Follicular / Q000175:diagnosis* / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone