title: [Prevention and therapy of cerebrospinal fluid leakage after translabyrinthine acoustic neuroma removal].
abstract: OBJECTIVE
  To evaluate the modified wound closure technique and other methods for preventing and treating the cerebrospinal fluid (CSF) leakage after removal of acoustic neuroma by translabyrinthine approach.
  
  
  METHODS
  In a series of 85 cases of acoustic neuroma surgery, two kinds of technique of wound closure, the traditional (as first group) and the modified (as second group), have been subsequently used to prevent CSF leakage. The incidences of CSF leak were analyzed respectively. Conservative and surgical treatments were applied to treatment the CSF leak.
  
  
  RESULTS
  In the first group, the CSF leak was 19.5% (8/41), and that of second group was 2.3% (1/44). There was significant difference between them (P = 0.013). The CSF leak mainly occurred in large acoustic neuromas surgery with traditional wound closure technique. Among 9 cases of CSF leaks, 3 were controlled by conservative method, 5 by one single revision surgery and one by two revisions.
  
  
  CONCLUSIONS
  The revision technique of wound closure could significantly reduce the incidence of CSF leakage after acoustic neuroma removal by translabyrinthine approach. The revision surgery is an effective method for stopping the CSF leak.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China. wuhao622@public7.sta.net.cn
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Rong-ping
authors.initials: RP
authors.lastname: Cao
authors.forename: Xiang-ping
authors.initials: XP
authors.lastname: Chen
authors.forename: Zhao-ji
authors.initials: ZJ
authors.lastname: Li
authors.forename: Shui-miao
authors.initials: SM
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000368:Aged; D002558:Cerebrospinal Fluid Otorrhea / Q000209:etiology / Q000628:therapy; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology / Q000628:therapy*; D007758:Ear, Inner / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control* / Q000628:therapy