title: [Evaluation of lesions of malignant lymphoma using histograms of regional SUV].
abstract: We designed new evaluation method using histogram of regional standardized uptake value (SUV) of every pixels of box shape volume of interest (VOI) on 18F-FDG PET. We evaluate lung and liver of normal volunteers and also the lesions of 4 cases of patients with non Hodgikin's malignant lymphoma using this method. SUV of pixels of pretreatment lesions shows log-normal distribution, whereas SUV of lung and liver show normal shape distribution. The next day of chemotherapy, 2 cases of them showed changes of distribution pattern from long-normal to normal with decrease of component of higher SUV values. No remarkable changes of distribution pattern were observed on other 2 cases, whereas decrease of regional mean values and max values of SUV were observed. And these findings were continued to 3 weeks later. These findings suggest that regional evaluation using histograms of SUV gives additional and predictive information for tumor therapies soon after the end of course.
authors.affiliation: Department of Radiology, Daiyukai General Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ito
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Yamane
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshiya
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Nagata
authors.forename: Hideo
authors.initials: H
authors.lastname: Uchida
authors.forename: Osami
authors.initials: O
authors.lastname: Daimaru
authors.forename: Kousuke
authors.initials: K
authors.lastname: Kato
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Nishida
authors.forename: Hideaki
authors.initials: H
authors.lastname: Hashimoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011859:Radiography; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed / Q000379:methods*
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18