Medication strategies in childhood aggression: a review.
OBJECTIVE
To review studies of psychopharmacological management of aggression in common childhood psychiatric disorders.


METHODS
Using OVID software, we searched Medline for studies that were undertaken in the last 30 years. Controlled and uncontrolled data are summarized for each condition.


RESULTS
A paucity of evidence-based information currently exists. Even so, specific indications from the existing literature can be suggested for several classes of psychotropics, particularly in conduct disorder (CD), attention-deficit hyperactivity disorder (ADHD), mood disorders, and other conditions.


CONCLUSIONS
Clinicians can use findings from reviewed controlled and, where necessary, uncontrolled studies to inform pharmacologic practice. This review offers suggestions for future research directions that will aid clinical practice.
Bassarath
Lindley
L
Centre for Addiction and Mental Health, 250 College Street, Suite 307, Toronto, ON M5T 1R8.
D000374:Aggression / Q000523:psychology*; D001008:Anxiety Disorders / Q000188:drug therapy / Q000523:psychology; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D002648:Child; D019955:Conduct Disorder / Q000188:drug therapy*; D018849:Controlled Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D019964:Mood Disorders / Q000188:drug therapy / Q000523:psychology; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*
D011619:Psychotropic Drugs