title: Do spinal cord injuries adversely affect serum lipoprotein profiles?
abstract: OBJECTIVE
  Previous reports indicate that dyslipidemia is very common in persons with spinal cord injury. This study aimed to examine the relationship between spinal cord injury and serum lipoprotein profiles.
  
  
  METHODS
  We assessed 28 healthy control subjects matched for age and sex and 60 persons (46 men and 14 women; mean age, 28.1 years) with spinal cord injury having a mean duration of injury of 3.6 +/- 0.8 years (range, 1-13 years).
  
  
  RESULTS
  Serum low-density lipoprotein cholesterol level was higher (109 +/- 37, 91 +/- 23.7 mg/dL, respectively) (p = 0.04) and serum high-density lipoprotein cholesterol level was lower (33 +/- 7.1, 44 +/- 7.4 mg/dL, respectively) (p < 0.001) in the patients with spinal cord injury than in the control. Apolipoprotein A-I level was significantly low (94 +/- 10.3, 103 +/- 11.5 mg/dl) (p = 0.003) and apolipoprotein B level was significantly high (93 +/- 15.6, 81 +/- 13.7mg/dL) (p = 0.004) in the group of spinal cord injury. No significant difference was observed the other parameters of these two groups.
  
  
  CONCLUSIONS
  Our results have shown that serum lipoprotein level should not be ignored for the follow-up of the patients with spinal cord injury.
authors.affiliation: Department of Biochemistry, Gulhane School of Medicine, 06018, Ankara, Turkey.
authors.forename: Taner
authors.initials: T
authors.lastname: Ozgurtas
authors.forename: Ridvan
authors.initials: R
authors.lastname: Alaca
authors.forename: Mahir
authors.initials: M
authors.lastname: Gulec
authors.forename: Turker
authors.initials: T
authors.lastname: Kutluay
mesh_terms: D000328:Adult; D000359:Aftercare / Q000379:methods; D016632:Apolipoprotein A-I / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000175:diagnosis / Q000209:etiology*; D006951:Hyperlipoproteinemias / Q000097:blood* / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008403:Mass Screening / Q000379:methods; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000150:complications*
chemical_list: D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL