Treatment Of Hookworm Infection With Furfurol.
Furfurol("Furfudol"), a new anthelmintics, was administered to 7 adults and 21 children (6-12 years old) in total amounts of 15.6 mg(base) for 1 to 3 days. It has proven to be effective against hookworms. The anthelmintic effect against hookworms with a single dose of 15.6 mg of furfurol was similar to that of a single dose of 2.5 gm of bephenium hydroxynaphthoate. However, when a total of 15.6 mg of the base was given to both children and adult, the side reactions were so mild that the drug can be administered for therapeutic regimens in mass treatment. Minor abdominal discomfort was the only common side effect. This is the primary advantage of furfurol as compared with bephenium hydroxynaphthoate. These results have indicated that furfurol is safe in therapeutic dosage and is an effective agent to treat patients infected with hookworms.
Choi
Dong Wik
DW
Department of Parasitology, School of Medicine, Kyungpook National University, Taegu, Korea.
Park
Sung Deok
SD
Kim
Jae Woun
JW
Choy
Chung Hun
CH
Kim
Yung Myung
YM