title: Case report: gnathostomiasis in two travelers to Zambia.
abstract: Gnathostomiasis is a systemic infection caused by migrating nematode larvae of the genus Gnathostoma. It is a zoonosis involving a wide variety of animals as intermediate and definitive hosts, and consumption of raw fish is the main risk factor. The condition is most commonly seen in southeastern Asia, but has been described in a number of other countries, all outside Africa. We report the infection in two travelers returning from southcentral Africa, who presented with non-specific symptoms and marked eosinophilia, and in whom schistosomiasis was initially suspected. The typical migratory skin lesions of gnathostomiasis appeared later. The infections responded well to albendazole. The patients acquired the infection in western Zambia; this region of Africa appears to be a newly identified risk area for gnathostomiasis in tourists who indulge in eating raw freshwater fish.
authors.affiliation: Department of Medicine, Division of Infectious Diseases University of Utah, Salt Lake City, Utah 84132-2405, USA. devon.hale@hsc.utah.edu
authors.forename: Devon C
authors.initials: DC
authors.lastname: Hale
authors.forename: Lucille
authors.initials: L
authors.lastname: Blumberg
authors.forename: John
authors.initials: J
authors.lastname: Frean
mesh_terms: D000368:Aged; D000818:Animals; D003530:Cyprinidae / Q000469:parasitology*; D016266:Food Parasitology; D006039:Gnathostoma; D006801:Humans; D008297:Male; D008875:Middle Aged; D012876:Skin Diseases, Parasitic / Q000175:diagnosis* / Q000469:parasitology; D017205:Spirurida Infections / Q000175:diagnosis* / Q000469:parasitology; D014195:Travel; D015024:Zambia; D015047:Zoonoses