[A retrospective analysis of 8 cases with primary central nervous system lymphoma].
OBJECTIVE
To make an inquiry into clinical features, treatment, and prognosis of primary central nervous system lymphoma (PCNSL).


METHODS
A retrospective analysis was carried out in a group of 8 patients confirmed diagnostic PCNSL by clinical findings and pathological examination.


RESULTS
The common clinical manifestation of PCNSL consisted of increased intracranial pressure, seizures, focal neurologic deficits. Studies of cerebrospinal fluid revealed protein elevation in the most patients. Neuroradiological examinations with CT and MRI both showed solitary or multiple lesion located cerebral hemisphere, periventricular, basal ganglia, corpus callosum. Pathological examination showed B-cell malignant lymphoma.


CONCLUSIONS
The patients with PCNSL usually did not show characteristic clinical manifestations or findings in imaging scanning. The brain biopsy pathological examination might be the only reliable method to confirm the diagnosis of the disease.
Zhou
X Q
XQ
Department of Neurology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China.
Liu
X Q
XQ
Kong
J C
JC
D000328:Adult; D000368:Aged; D016543:Central Nervous System Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies