Synthesis of 3-substituted quinolines via transition-metal-catalyzed reductive cyclization of o-nitro Baylis-Hillman acetates.
Reductive cyclization of o-nitro-substituted Baylis-Hillman acetates by carbon monoxide, catalyzed by [CpFe(CO)(2)](2), gives moderate to good yields of 3-substituted quinolines.
O'Dell
David K
DK
Department of Chemistry and Biochemistry, University of Oklahoma, 620 Parrington Oval, Norman, Oklahoma 73019, USA.
Nicholas
Kenneth M
KM