title: [A case report of complete remission of liver metastases from colorectal cancer treated with continuous hepatic arterial infusion].
abstract: We encountered a patient with liver metastases from colorectal cancer in whom continuous hepatic arterial infusion brought complete remission. A 58-year-old man was admitted to our hospital for advanced rectal cancer with multiple liver metastases. He underwent a low anterior resection (D2). Continuous hepatic arterial infusion of 5-FU (250 mg/day) with a weekly arterial infusion of MMC (4 mg) was performed for 14 days. Six continuous hepatic arterial infusions resulted in a complete remission. The patient has been free from any sign of recurrence for 37 months after the operation. Continuous hepatic arterial infusion using 5-FU and MMC seems to be effective in the treatment of multiple liver metastases from colorectal cancer.
authors.affiliation: Dept. of Surgery, Kinan General Hospital.
authors.forename: Toshiteru
authors.initials: T
authors.lastname: Tokunaga
authors.forename: Junichi
authors.initials: J
authors.lastname: Sumimura
authors.forename: Katsuhide
authors.initials: K
authors.lastname: Yoshidome
authors.forename: Shigeo
authors.initials: S
authors.lastname: Fujita
authors.forename: Kou
authors.initials: K
authors.lastname: Tsuji
authors.forename: Fuminori
authors.initials: F
authors.lastname: Oota
authors.forename: Naohisa
authors.initials: N
authors.lastname: Tsuboyama
authors.forename: Isamu
authors.initials: I
authors.lastname: Nagai
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage
chemical_list: D016685:Mitomycin; D005472:Fluorouracil