[Comparative study of pulmonary function after conventional ultrafiltration or modified ultrafiltration during cardiac surgery of infants].
OBJECTIVE
To compare the effects of conventional ultrafiltration and modified ultrafiltration in protecting patients' pulmonary function during cardiopulmonary bypass.


METHODS
Thirty infants patients (less than 7 kg) were divided into two groups: conventional ultrafiltration group (CUF, n = 15) and modified ultrafiltration group (MUF, n = 15). The volume of ultrafiltration, transfusion, hematocrit (HCT) before and after ultrafiltration, patients' respiration function (respiration index, A-aDO2, airway pressure), the time of mechanical ventilation and ICU in the two groups were respectively monitored.


RESULTS
The transfusion in MUF group was significantly less than in CUF group (P < 0.01), and the volume of ultrafiltration in MUF group was significantly more than in CUF group (P < 0.01). The time of mechanical ventilation and ICU staying in MUF group were significantly shorter in MUF group than that in CUF group (P < 0.05). At 12 and 24 hours after operations, the A-aDO2 in MUF group was lower than that in CUF group (P < 0.05), and the respiratory index in MUF group was higher than that in CUF group (P < 0.05).


CONCLUSIONS
The modified ultrafiltration can effectively improve pulmonary function after operations for low weight infants.
Liu
Jin-ping
JP
Department of Cardiopulmonary Bypass, Cardiovascular Institute, Fu Wai Hospital, CAMS, PUMC, Beijing 100037, China. Jinping2784@sina.com
Long
Cun
C
Feng
Zheng-yi
ZY
Ji
Bing-yang
BY
Li
Chun-hua
CH
D002315:Cardiopulmonary Bypass; D005260:Female; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008168:Lung / Q000503:physiopathology*; D008297:Male; D012129:Respiratory Function Tests; D014462:Ultrafiltration / Q000379:methods