title: [Detection of eosinophil cationic protein and E-selectin in serum and nasal lavage fluid in patients with allergic rhinitis].
abstract: OBJECTIVE
  To evaluate the role of eosinophil cationic protein (ECP) and serum soluble E-selectin (sE-selectin) in patients with allergic rhinitis.
  
  
  METHODS
  The sE-selectin were detected from 30 allergic patients and 20 normal individuals by enzyme-linked immunosorbent assay (ELISA). The ECP in serum and nasal lavage fluid was assayed with pharmacia CAP system.
  
  
  RESULTS
  The level of sE-selectin in patients with allergic rhinitis was(41.846 +/- 12.21) ng/ml, higher than that in control (10.678 +/- 2.458) ng/ml. The level of ECP in serum and nasal lavage fluid from patients with allergic rhinitis was significantly higher than that from normal controls. The level of ECP in nasal lavage fluid was much higher than that in serum.
  
  
  CONCLUSIONS
  ECP and sE-selectin play a role in pathogenesis of allergic rhinitis.
authors.affiliation: Department of Otorhinolaryngology, First Hospital, Chongqing University of Medical Sciences, Chongqing 400016, China.
authors.forename: Su-ling
authors.initials: SL
authors.lastname: Hong
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.forename: Jiang-ju
authors.initials: JJ
authors.lastname: Huang
authors.forename: Yu-cheng
authors.initials: YC
authors.lastname: Yang
authors.forename: Hou-yong
authors.initials: HY
authors.lastname: Kang
authors.forename: Yi-qin
authors.initials: YQ
authors.lastname: Wang
authors.forename: Rong
authors.initials: R
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000032:analysis* / Q000502:physiology; D019040:E-Selectin / Q000032:analysis* / Q000502:physiology; D047091:Eosinophil Granule Proteins; D004804:Eosinophils / Q000737:chemistry; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D017817:Nasal Lavage Fluid / Q000737:chemistry*; D012221:Rhinitis, Allergic, Perennial / Q000097:blood / Q000378:metabolism*; D012260:Ribonucleases / Q000032:analysis* / Q000502:physiology
chemical_list: D001798:Blood Proteins; D019040:E-Selectin; D047091:Eosinophil Granule Proteins; D007073:Immunoglobulin E; D012260:Ribonucleases