[Diagnosis and pharmacologic therapy of osteoporosis].
Osteoporosis is a major health care problem of the developed countries. During the last decades, female osteoporosis has been in the center of interest. However, it had to be realized that a significant number of men suffer in this disorder. Beside patient's history and physical examination, bone densitometry, X-ray and biochemical tests are the basis of the diagnosis. Bone densitometry provides accurate information on bone quantity but it does not identify the causes of a potential reduction in bone mineral content. X-ray and laboratory examinations are absolutely essential for differential diagnosis. In the treatment of involutional osteoporosis, a number of effective drugs are available. Their effects on bone tissue have been proven by the methods of evidence-based medicine. In this review, the recent developments in the diagnosis and therapy of osteoporosis have been summarized.
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Semmelweis Egyetem Altalános Orvostudományi Kar, I. Belgyógyászati Klinika, Budapest. lakpet@bell.sotehu
D015502:Absorptiometry, Photon; D015519:Bone Density / Q000187:drug effects; D002116:Calcitonin / Q000627:therapeutic use; D017610:Calcium Compounds / Q000627:therapeutic use; D003720:Densitometry; D004164:Diphosphonates / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis* / Q000188:drug therapy*; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis / Q000188:drug therapy; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use; D014807:Vitamin D / Q000627:therapeutic use
D017610:Calcium Compounds; D004164:Diphosphonates; D020845:Selective Estrogen Receptor Modulators; D014807:Vitamin D; D002116:Calcitonin