T helper type-2 cytokine responses: potential therapeutic targets.
T helper (Th)2 cell-mediated immune responses are associated with parasitic helminth infections and atopic disorders. The production of interleukin (IL)-4, IL-5, IL-9 and/or IL-13 by Th2 cells mediates a range of responses that can be protective or pathogenic. Progress has recently been made in elucidating the mechanism of Th2 immunity, which has therapeutic potential for the treatment of allergic diseases.
Jarnicki
Andrew G
AG
Department of Biochemistry, Trinity College, Dublin 2, Ireland.
Fallon
Padraic G
PG
D000818:Animals; D016207:Cytokines / Q000235:genetics / Q000276:immunology*; D016503:Drug Delivery Systems; D020868:Gene Silencing; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000628:therapy; D007167:Immunotherapy; D018121:Receptors, Cytokine / Q000378:metabolism; D018417:Th1 Cells / Q000276:immunology / Q000473:pathology; D018418:Th2 Cells / Q000276:immunology* / Q000473:pathology
D016207:Cytokines; D018121:Receptors, Cytokine