title: Influence of ablation parameters on refractive changes after phototherapeutic keratectomy.
abstract: OBJECTIVE
  The aim of the current study was to control the hypothetical effects of decreased laser energy delivered to the peripheral cornea during phototherapeutic keratectomy (PTK) and provide quantitative calculation of induced low and high order aberrations.
  
  
  METHODS
  We employed a model eye to simulate the refractive effect of homogeneous laser corneal irradiation, as in PTK, for different laser fluences (range 125 to 225 mJ/cm2) and treatment depths up to 200 microm.
  
  
  RESULTS
  The hyperopic shift induced by the relatively lower energy delivered at the peripheral ablation zone during PTK was proportional to the treatment depth and inversely proportional to the energy fluence. The hyperopic shift calculated using the above ablation parameters was lower compared to previously reported clinical results. Higher order wavefront aberration (total root mean square) changes were of minimal significance for treatment depths up to 200 microm.
  
  
  CONCLUSIONS
  After PTK, a hyperopic shift cannot be attributed to the energy delivery method alone. Modification of laser energy delivery algorithms may only minimize PTK-induced hyperopia.
authors.affiliation: University of Crete, School of Medicine, Vardinoyannion Eye Institute, Heraklion, Crete, Greece. ginis@med.uoc.gr
authors.forename: Harilaos S
authors.initials: HS
authors.lastname: Ginis
authors.forename: Vikentia J
authors.initials: VJ
authors.lastname: Katsanevaki
authors.forename: Ioannis G
authors.initials: IG
authors.lastname: Pallikaris
mesh_terms: D003315:Cornea / Q000601:surgery*; D003318:Corneal Opacity / Q000601:surgery*; D006801:Humans; D006956:Hyperopia / Q000209:etiology* / Q000517:prevention & control; D054018:Lasers, Excimer; D008433:Mathematics; D008954:Models, Biological; D018903:Photorefractive Keratectomy / Q000009:adverse effects* / Q000379:methods; D011183:Postoperative Complications