title: [CVS-cardiac thrombosis related in a child with an intracranial germinoma].
abstract: We report a case of a CVC infection with a grave cardiac thrombosis in a child afflicted with intracranial functioning germinoma. During the second chemotherapeutic cycle we found a positive blood culture and a partial CVC occlusion; echocardiography showed a 2 cm diameter interatrial thrombus. After removal of the CVC a voluminous thrombus in the right atrium persisted. The profibrinolytic factor's concentration was normal, and so we preferred to use aspirin, the most common antiplatelet agent, combined with antibiotic and antimycotis therapy. This treatment allowed us to observe the disappearance of the thrombus by 25 days.
authors.affiliation: Oncoematologia Pediatrica, II Clinical Pediatrica, Università degli Studi di Milano. Dario.Portaleone@unimi.it
authors.forename: D
authors.initials: D
authors.lastname: Portaleone
authors.forename: P
authors.initials: P
authors.lastname: Poggio
authors.forename: E
authors.initials: E
authors.lastname: Vegetti
authors.forename: L
authors.initials: L
authors.lastname: Lavigna
authors.forename: M
authors.initials: M
authors.lastname: Moioli
authors.forename: V
authors.initials: V
authors.lastname: Carnelli
mesh_terms: D001932:Brain Neoplasms / Q000150:complications*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D004452:Echocardiography; D005260:Female; D018237:Germinoma / Q000150:complications*; D006331:Heart Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000209:etiology*