Dielectrophoretic assay of bacterial resistance to antibiotics.
The dielectrophoretic collection spectra of antibiotic-sensitive and antibiotic-resistant strains of Staphylococcus epidermidis have been determined. These indicate that in the absence of antibiotic treatment there is a strong similarity between the dielectric properties of sensitive and resistant strains, and that there is a significant difference between the sensitive strains before and after treatment with the antibiotic streptomycin after 24 h exposure. This method offers possibilities for the assessment of bacterial resistance to antibiotics.
Johari
Juliana
J
School of Engineering, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Hübner
Yvonne
Y
Hull
Judith C
JC
Dale
Jeremy W
JW
Hughes
Michael P
MP
D015169:Colony Count, Microbial / Q000379:methods*; D004351:Drug Resistance / Q000502:physiology*; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013212:Staphylococcus epidermidis / Q000145:classification / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification*; D013307:Streptomycin / Q000494:pharmacology*
D013307:Streptomycin