[Isolation of a kind of endophytic fungus which can produce taxol compounds].
OBJECTIVE
To isolate a kind of endophytic fungus which can produce taxol compounds from the bark of Taxus Cuspidata Sieb et Zucc.


METHODS
Endophytic fungus was isolated from the bark of Taxus Cuspidata Sieb et Zucc by aseptic techniques and the analysis of the culture fluid from the fermentation of fungus was carried out by high performance liquid chromatography (HPLC).


RESULTS
Endophytic fungus was obtained from the bark of Taxus Cuspidata Sieb et Zucc and the chemical analysis showed that the culture of fungus contain taxol compounds.


CONCLUSIONS
Endophytic fungus which can produce taxol compounds exists in the bark of Taxus Cuspidata Sieb et Zucc.
Shao
A J
AJ
Department of Pharmacognosy, Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Lin
S F
SF
Zhang
S J
SJ
Li
X M
XM
Huang
L Q
LQ
Chen
M
M
Wu
Z G
ZG
Dai
R Q
RQ
Liu
L
L
D002851:Chromatography, High Pressure Liquid; D005658:Fungi / Q000302:isolation & purification* / Q000378:metabolism; D017239:Paclitaxel / Q000032:analysis / Q000096:biosynthesis; D024301:Plant Bark / Q000382:microbiology; D020946:Taxus / Q000382:microbiology*
D017239:Paclitaxel