title: Squamous cell carcinoma of the lower lip and supra-omohyoid neck dissection.
abstract: OBJECTIVE
  The aim of this study is to evaluate our approach to patients with squamous cell carcinoma of lower lip.
  
  
  METHODS
  This study includes 31 lower lip squamous cell carcinomas followed up between 1994 and 2000. Primary treatment was applied to 28 patients of whom 23 were in stages I-II and five in stages III-IV. Three patients presented locoregional recurrence. Neck dissection was performed during primary lip resection in patients with palpable cervical lymph node involvement. Patients with unpalpable cervical lymph nodes were divided into two subgroups: one was submitted to elective neck dissection (n = 11) and the other had isolated lip resection (n = 8). Unilateral or bilateral selective supra-omohyoid neck dissection (SOHND) was performed according to the localisation of the disease. Radical dissection was performed in a secondary intervention, when SOHND revealed lymph node metastases. Radiotherapy and chemotherapy were applied for curative and/or adjuvant treatment in addition to surgery in patients with locoregional recurrence and metastatic lymph nodes or with perineural involvement.
  
  
  RESULTS
  Occult cervical metastasis within a single lymph node was found in one of the 11 No patients who underwent elective neck dissection. Delayed neck metastasis developed in one of the eight patients in whom isolated lip resection (without neck exploration) was performed. Chemoradiotherapy was administered to this patient, but he died. Neck metastasis was established histologically in four of five patients in stages III-IV. Postoperative radiotherapy was used on these patients. One of the patients in this group died due to inoperable local recurrence in the neck, another died because of distant metastasis. Local mandibular recurrence was seen in one of these patients after three years.
  
  
  CONCLUSIONS
  Six patients (19%) died due to lower lip carcinoma in this series. Our findings show the importance of elective neck dissection and intact surgical resection margins.
authors.affiliation: Yüzüncü Yil University Medical Faculty, Department of Otorhinolaringology, Van, Turkey. ahkutluhan@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Kutluhan
authors.forename: M
authors.initials: M
authors.lastname: Kiriş
authors.forename: Z
authors.initials: Z
authors.lastname: Kaya
authors.forename: E
authors.initials: E
authors.lastname: Kisli
authors.forename: V
authors.initials: V
authors.lastname: Yurttaş
authors.forename: M
authors.initials: M
authors.lastname: Içli
authors.forename: M
authors.initials: M
authors.lastname: Kösem
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology* / Q000601:surgery*; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery