Lipids and the exocytotic machinery of eukaryotic cells.
The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.
Bankaitis
Vytas A
VA
Department of Cell and Developmental Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7090, USA. vytas@med.unc.edu
Morris
Andrew J
AJ
D000818:Animals; D004721:Endoplasmic Reticulum / Q000378:metabolism; D005057:Eukaryotic Cells / Q000378:metabolism*; D005089:Exocytosis / Q000502:physiology*; D006056:Golgi Apparatus / Q000378:metabolism; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism*; D021381:Protein Transport / Q000502:physiology; D011506:Proteins / Q000378:metabolism
D008563:Membrane Lipids; D011506:Proteins