title: [Studies on the chemical constituents of the aerial part of Cimicifuga foetida L].
abstract: OBJECTIVE
  To look for new active constituents from the aerial part of Cimicifuga foetida L.
  
  
  METHODS
  Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.
  
  
  RESULTS
  Five 9,19-cycloartane triterpenoid saponins and one sitosterol saponin were obtained and identified as cimifoetiside I [12 beta-hydroxycimigenol-3-O-beta-D-galactoyranoside, (1)], cimifoetiside II [(23R,24R) cimigenol-3-O-beta-D-galactopyranoside, (2)], cimigenol-3-O-beta-D-galactopyranoside (3), 12 beta-hydroxycimigenol-3-O-beta-D-xylopyranoside (4), 12 beta-hydroxycimigenol-3-O-alpha-L-arabinopyranoside (5), daucosterol (6).
  
  
  CONCLUSIONS
  Compounds 1 and 2 are new and compounds 4 and 5 were isolated from this plant for the first time.
authors.affiliation: Institute of Medicinal Plant, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
authors.forename: Rui-le
authors.initials: RL
authors.lastname: Pan
authors.forename: Di-hua
authors.initials: DH
authors.lastname: Chen
authors.forename: Jian-yong
authors.initials: JY
authors.lastname: Si
authors.forename: Xiao-hong
authors.initials: XH
authors.lastname: Zhao
authors.forename: Lian-gang
authors.initials: LG
authors.lastname: Shen
mesh_terms: D031885:Cimicifuga / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D012855:Sitosterols; C483647:cimifoetiside I; C483648:cimifoetiside II; C011015:lyoniside