Molluscicidal activity of Physalis angulata L. extracts and fractions on Biomphalaria tenagophila (d'Orbigny, 1835) under laboratory conditions.
The main objective of this research is to evaluate the molluscicide activity of Physalis angulata L. Biomphalaria tenagophila specimens under laboratory conditions. Extracts and fractions were supplied by the Laborat rio de Qu mica de Produtos Naturais, Farmanguinhos-Fiocruz. Experiments were performed according to the methodology described by the World Health Organization for molluscicide tests using the concentrations from 0.1 to 500 mg/l of the extracts, fractions and of a pool of physalins modified steroids present in this species. The results show that ethyl acetate and acetone extracts from the whole plant, the ethanolic extracts of the roots and the physalins pool from stems and leaves were active. Only the whole plant extracts were available in sufficient quantity for the determination of LD50 and LD90 values.
dos Santos
José Augusto A
JA
Núcleo de Biologia e Controle de Endo e Ectoparasita de Interesse Médico e Veterinário, Departamento de Biologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, 21045-900, Brasil. santosja@ioc.fiocruz.br
Tomassini
Therezinha Coelho B
TC
Xavier
Deise Cristina Drummond
DC
Ribeiro
Ivone Maria
IM
da Silva
Melissa Teixeira G
MT
de Morais Filho
Zenildo Buarque
ZB
D000818:Animals; D001700:Biomphalaria / Q000187:drug effects*; D007928:Lethal Dose 50; D008975:Molluscacides / Q000494:pharmacology*; D032321:Physalis / Q000737:chemistry*; D010936:Plant Extracts / Q000145:classification / Q000494:pharmacology
D008975:Molluscacides; D010936:Plant Extracts