Androgen effects on body composition.
Androgens are known to have a role in the body fat, muscle size, muscle performance and physical function differences seen between hypogonadal and eugonadal men. The results of investigations into effects of testosterone on body composition, fat metabolism and muscle anabolism are reviewed here. Testosterone dose-response relationships are presented in studies of the effects of physiologic and supraphysiologic doses with and without exercise in young hypogonadal men, older men with low testosterone levels and in chronic illness states.
Bhasin
Shalender
S
Division of Endocrinology, Metabolism and Molecular Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA. sbhasin@ucla.edu
Woodhouse
Linda
L
Storer
Thomas W
TW
D000273:Adipose Tissue / Q000187:drug effects; D001823:Body Composition / Q000187:drug effects*; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology*
D005227:Fatty Acids; D013739:Testosterone