title: Nanoencapsulation of [60] fullerene by a novel sugar-based polymer.
abstract: [60] Fullerene has been nanoencapsulated by the formation of an inclusion complex with a beta-cyclodextrin-containing lactose copolymer. The cyclodextrin polymer was synthesized by reaction of beta-cyclodextrin chlorotriazine with beta-lactose, and the polymer was highly soluble in water. Encapsulation of the carbon allotrope was achieved by forming a stable inclusion complex between the water-soluble cyclodextrin and [60] fullerene by a new synthetic procedure. Preliminary studies indicate that this complex has potential for biomedical applications because of its radical scavenging properties.
authors.affiliation: Laboratory of Applied Macromolecular Chemistry, Department of Materials Science and Engineering, Kwangju Institute of Science and Technology, 1 Oryong-dong, Buk-gu, Kwangju 500-712, South Korea.
authors.forename: C N
authors.initials: CN
authors.lastname: Murthy
authors.forename: S J
authors.initials: SJ
authors.lastname: Choi
authors.forename: K E
authors.initials: KE
authors.lastname: Geckeler
mesh_terms: D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D003505:Cyclodextrins / Q000737:chemistry*; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry; D004339:Drug Compounding / Q000379:methods; D037741:Fullerenes / Q000008:administration & dosage* / Q000737:chemistry; D007785:Lactose / Q000737:chemistry*; D008863:Microspheres; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D011108:Polymers / Q000138:chemical synthesis; D012995:Solubility; D014867:Water / Q000737:chemistry; D047392:beta-Cyclodextrins
chemical_list: D020099:Coated Materials, Biocompatible; D003505:Cyclodextrins; D004337:Drug Carriers; D037741:Fullerenes; D011108:Polymers; D047392:beta-Cyclodextrins; D014867:Water; D007785:Lactose; C031215:betadex; C069837:fullerene C60