Palladium-catalyzed [3+2] intramolecular cycloaddition of alk-5-ynylidenecyclopropanes: a rapid, practical approach to bicyclo[3.3.0]octenes.
Readily accessible hex-5-ynylidenecyclopropane derivatives cycloisomerize to bicyclic five-membered carbocycles upon heating with catalytic amounts of a palladium complex.
Delgado
Alejandro
A
Departamento de Química Orgánica y Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Rodríguez
J Ramón
JR
Castedo
Luis
L
Mascareñas
José L
JL
D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis*; D002384:Catalysis; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry*; D009795:Octanes / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry
D001643:Bridged Bicyclo Compounds; D003521:Cyclopropanes; D009795:Octanes; D010165:Palladium