title: Toxoplasmosis transmitted to a newborn from the mother infected 20 years earlier.
abstract: OBJECTIVE
  To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis.
  
  
  METHODS
  Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newborn who presented with a focal necrotizing retinochoroiditis characteristic of toxoplasmosis, as well as positive immunoglobulin (Ig) G and M serology for toxoplasmosis. The workup was negative for other entities.
  
  
  CONCLUSIONS
  This case suggests that women with old retinal scars due to toxoplasmosis and long-standing IgG antibodies to toxoplasmosis are also at risk of transmitting this disease to the fetus.
authors.affiliation: Clinica Silveira, Erechim, Rio Grande do Sul, Brazil.
authors.forename: Claudio
authors.initials: C
authors.lastname: Silveira
authors.forename: Rosane
authors.initials: R
authors.lastname: Ferreira
authors.forename: Cristina
authors.initials: C
authors.lastname: Muccioli
authors.forename: Robert
authors.initials: R
authors.lastname: Nussenblatt
authors.forename: Rubens
authors.initials: R
authors.lastname: Belfort
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D004359:Drug Therapy, Combination; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D011739:Pyrimethamine / Q000627:therapeutic use; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D013411:Sulfadiazine / Q000627:therapeutic use; D014122:Toxoplasma / Q000276:immunology; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission*; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission*
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D013411:Sulfadiazine; D011739:Pyrimethamine