A case of hemiparesis associated with cranial nerve lesions due to intravascular lymphomatosis(2003:4b).
Intravascular lymphomatosis is a rare variant of non-Hodgkin's lymphoma with an unusual predilection for the central nervous system. Most cases are not diagnosed until postmortem because of variable clinical presentation and non-specific laboratory findings. We studied a 41-year-old lady who presented with progressive neurological symptoms. MR showed multifocal grey and white matter lesions. Brain biopsy showed an intravascular lymphoma of the B-cell lineage. This report illustrates the ischaemic origin of the radiological lesions, as they are all hyperintense on the diffusion-weighted images. This has, to our knowledge, never been published before. MR did not show any enhancement after intravenous Gadolinium-DTPA (parenchymal or meningeal)which is a very uncommon finding in this entity. Intravascular lymphomatosis should be taken into account in the differential diagnosis of repeated cerebral ischemia of unclear aetiology.
De Bruecker
Y
Y
Department of Radiology, University Hospitals, Catholic University of Leuven, Leuven, Belgium.
Demaerel
P
P
Wilms
G
G
Sciot
R
R
Ballaux
F
F
Robberecht
W
W
D000328:Adult; D005158:Facial Paralysis / Q000209:etiology*; D005260:Female; D006429:Hemiplegia / Q000209:etiology*; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000209:etiology*; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging