title: [Exercise-induced anaphylaxis after apple intake].
abstract: Exercise-induced anaphylaxis frequently is related to food ingestion, so that it receives the name of "food-dependent exercise-induced anaphylaxis". The food identification is difficult in some patients. We report two patients with apple-dependent exercise-induced anaphylaxis.
  
  
  METHODS
  hematimetries, biochemistries, VMA and 5-HIAA in urine. Complement levels, antinuclear antibodies and viruses serology.
  skin prick test with a common inhalant. Skin prick test and prick by prick with different foods. Total Ig E level and specific Ig E determination by the CAP-Pharmacia System. Oral challenge test with apple, exercise test and exercise challenge test after eating an apple. Prick by prick test with fresh apple was positive. Specific Ig E determination by the CAP-Pharmacia System revealed a positive result. We get to reproduce the episode with an exercise challenge test after eating an apple in the same conditions of usual exercise in both patients.
authors.affiliation: Clínica Universitaria Puerta de Hierro de Madrid. España. lsanchezmorillas@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Sánchez-Morillas
authors.forename: A
authors.initials: A
authors.lastname: Iglesias Cadarso
authors.forename: L
authors.initials: L
authors.lastname: Zapatero Remón
authors.forename: M
authors.initials: M
authors.lastname: Reaño Martos
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez Mosquera
authors.forename: M I
authors.initials: MI
authors.lastname: Martínez Molero
mesh_terms: D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000209:etiology*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D027845:Malus / Q000009:adverse effects*; D005082:Physical Exertion; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications; D012882:Skin Tests; D013177:Sports
chemical_list: D007073:Immunoglobulin E