Lung, gastric, and soft tissue uptake of Tc-99m MDP and Ga-67 citrate associated with hypercalcemia.
Metastatic calcifications are associated with chronic renal failure, hyperparathyroidism, metastatic neoplasms, hypervitaminosis D, and hypercalcemia of other origins. Bone scanning agents accumulate within these extraskeletal metastatic calcifications. The authors describe two patients with hypercalcemia associated with Tc-99m MDP uptake in the lungs, stomach, and soft tissues. Ga-67 scintigraphy was also performed and showed increased uptake in the same locations as those of Tc-99m MDP, suggesting the existence of an inflammatory process. Despite adequate treatment, only partial resolution of extraskeletal uptake was observed.
Castaigne
Catherine
C
Department of Nuclear Medicine, Hôpital Brugmann, Brussels, Belgium. catherine.castaigne@stpierre-bru.be
Martin
Philippe
P
Blocklet
Didier
D
D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000000981:diagnostic imaging; D003238:Connective Tissue / Q000000981:diagnostic imaging*; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D006934:Hypercalcemia / Q000000981:diagnostic imaging*; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013270:Stomach / Q000000981:diagnostic imaging*; D013669:Technetium Tc 99m Medronate
D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate