[Clinical application and animal experiment of thoracic tracheal reconstruction by using pulmonary tissue flap].
OBJECTIVE
To study the usability of pulmonary tissue flap in the reconstruction of the thoracic trachea.


METHODS
Over half perimeter anterior and posterior wall and 6 to 8 tracheal cartilagious rings of dog trachea were resected. The nickel-titanium alloy mesh stent was placed inside the lumen for repair of the defect of the tracheal wall by nearby pulmonary tissue flap with the vascularized segment. The dogs were killed from 2 months to 12 months after operation. Specimens were taken and observed under light and electron microscope. Clinically, 4 patients were treated by this way operation [right common tracheal scarred stenosis and atresia (1), mixed cancerization in the lower part of the common trachea (1) and left common tracheal carcinoid (2)].


RESULTS
No stenosis and granulation tissue were observed in the prosthetic lumen, in which there was comparative continuous stratified ciliated columnar epithelium. All patients recovered respiratory function.


CONCLUSIONS
Pulmonary tissue flap is a promising prosthesis of thoracic tracheal reconstruction.
Shi
Wen-jun
WJ
Department of Thoracic Surgery, Second Clinical College, China Medical University, Shenyang 110004, China.
Zhang
Su-ning
SN
Yang
Wei
W
Zhao
Jun-gang
JG
Zhao
Yang
Y
Liu
Jun
J
D000818:Animals; D004285:Dogs; D005260:Female; D006801:Humans; D008168:Lung; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D013524:Surgical Flaps; D014132:Trachea / Q000601:surgery*