title: Two new bromotyrosine-derived metabolites from the sponge Psammaplysilla purpurea.
abstract: Two new bromotyrosine-derived metabolites (1, 2) have been isolated along with the known compounds 3,5-dibromo-4-methoxyphenylacetonitrile, 3-bromo-4-methoxyphenylacetonitrile, 3-bromo-4-hydroxyphenylacetonitrile, 1-hydroxyuracil, 1-methoxyhemibastadin 2, purpuramine H and a steroid 5alpha,8alpha-epidioxycholest-6-en-3beta-ol from the sponge Psammaplysilla purpurea. Compounds 1 and 2 were characterized by interpretation of their spectral data. The antibacterial activity of these compounds is summarized.
authors.affiliation: Natural Products Laboratory, Organic Division-I, Indian Institute of Chemical Technology.
authors.forename: Thirumani Venkateshwar
authors.initials: TV
authors.lastname: Goud
authors.forename: Masuna
authors.initials: M
authors.lastname: Srinivasulu
authors.forename: Vanimireddy Lakshmi Niranjan
authors.initials: VL
authors.lastname: Reddy
authors.forename: Adelli Vijender
authors.initials: AV
authors.lastname: Reddy
authors.forename: Tadikamalla Prabhakar
authors.initials: TP
authors.lastname: Rao
authors.forename: Dondapati Srujan
authors.initials: DS
authors.lastname: Kumar
authors.forename: Upadhyayula Suryanaramyana
authors.initials: US
authors.lastname: Murty
authors.forename: Yenamandra
authors.initials: Y
authors.lastname: Venkateswarlu
mesh_terms: D000818:Animals; D011161:Porifera / Q000737:chemistry*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: C475724:bromotyrosine; D014443:Tyrosine