Universal stress proteins and Mycobacterium tuberculosis.
Mycobacterium tuberculosis expresses universal stress proteins (USPs) when its growth is retarded by oxygen depletion. This class of proteins is emerging as being important in the resistance of bacteria to stress and prolonged growth arrest. Here we assess the properties of USPs and their relevance to mycobacteria.
O'Toole
Ronan
R
Department of Biological Sciences, Imperial College London, London, SW7 2AZ, UK. r.otoole@imperial.ac.uk
Williams
Huw D
HD
D001426:Bacterial Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D006360:Heat-Shock Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity*
D001426:Bacterial Proteins; D006360:Heat-Shock Proteins; C078564:universal stress protein A, Bacteria