title: Estimation of animal transfer factors for radioactive isotopes of iodine, technetium, selenium and uranium.
abstract: In post-closure radiological safety assessments of repositories for solid radioactive wastes, transfers of radionuclides to animal products are typically characterised using Transfer Factors (TFs), defined as the ratio of the concentration of the radionuclide in the animal product of interest to the rate of intake in diet. Such transfer factors can be measured directly in experimental studies, but they can also be estimated by use of biokinetic models for uptake and retention of radionuclides in animals. Based on a review of the literature, biokinetic models have been developed for the uptake and retention of iodine, technetium, selenium and uranium. These biokinetic models allow TF values to be estimated for different types of animals and for different animal lifetimes. For each radionuclide considered, reference values and ranges of TF values are estimated. These are summarised in Table 1.
authors.affiliation: Mike Thorne and Associates Limited, Abbotsleigh, Kebroyd Mount, Ripponden, Halifax, West Yorkshire HX6 3JA, UK . mikethorneltd@aol.com
authors.forename: M C
authors.initials: MC
authors.lastname: Thorne
mesh_terms: D000818:Animals; D020387:Food Chain; D005544:Forecasting; D007457:Iodine Radioisotopes / Q000493:pharmacokinetics*; D007700:Kinetics; D008962:Models, Theoretical; D011850:Radioactive Waste; D018570:Risk Assessment; D012644:Selenium Radioisotopes / Q000493:pharmacokinetics*; D013667:Technetium / Q000493:pharmacokinetics*; D014501:Uranium / Q000493:pharmacokinetics*
chemical_list: D007457:Iodine Radioisotopes; D011850:Radioactive Waste; D012644:Selenium Radioisotopes; D014501:Uranium; D013667:Technetium