Ciclopirox for the treatment of superficial fungal infections: a review.
Ciclopirox is a broad-spectrum antifungal agent that also exhibits anti-inflammatory and antibacterial activity. The lotion and cream formulations of ciclopirox are effective in many types of infection, including tinea corporis/cruris, tinea pedis, cutaneous candidiasis, pityriasis (tinea) versicolor, and seborrheic dermatitis. The new ciclopirox gel 0.77% formulation is also indicated for the treatment of seborrheic dermatitis of the scalp, interdigital tinea pedis and tinea corporis.
Gupta
Aditya K
AK
Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center (Sunnybrook site) and the University of Toronto, Toronto, Canada. agupta@execulink.com
Skinner
Alayne R
AR
D000287:Administration, Topical; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000077768:Ciclopirox; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D005658:Fungi / Q000145:classification / Q000187:drug effects*; D006801:Humans; D008297:Male; D020714:Maximum Tolerated Dose; D008826:Microbial Sensitivity Tests; D011728:Pyridones / Q000494:pharmacology / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D012869:Skin Absorption / Q000187:drug effects; D016896:Treatment Outcome
D000935:Antifungal Agents; D011728:Pyridones; D000077768:Ciclopirox