title: [Surgical treatment of gastrointestinal stromal tumors: personal cases].
abstract: Surgical management of gastrointestinal stromal tumors: our experience. Gastrointestinal stromal tumors (GIST) are rare neoplasm even if they are the most common mesenchimal malignancies of the gastrointestinal tract. GIST have long been a source of confusion and controversy, in particular to define their pathological classification, preoperative diagnosis, management strategies, and prognosis. A radical resection of the tumor is often possible and always recommended. Recent studies have identified its principal pathogenic defect. An effective adjuvant therapy treatment (STI571) have been found for advanced and metastatic GIST.
authors.affiliation: UO Chirurgia Generale Ospedale S Paolo, ASL 2, Savona.
authors.forename: A
authors.initials: A
authors.lastname: Schirru
authors.forename: D
authors.initials: D
authors.lastname: Cavaliere
authors.forename: U
authors.initials: U
authors.lastname: Cosce
authors.forename: M
authors.initials: M
authors.lastname: Scarimbolo
authors.forename: G
authors.initials: G
authors.lastname: Griseri
authors.forename: I
authors.initials: I
authors.lastname: Caristo
authors.forename: M
authors.initials: M
authors.lastname: Bianchi
authors.forename: E
authors.initials: E
authors.lastname: Ingravaglieri
authors.forename: D
authors.initials: D
authors.lastname: Aiello
authors.forename: E
authors.initials: E
authors.lastname: Venturino
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000601:surgery; D018572:Disease-Free Survival; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005500:Follow-Up Studies; D005743:Gastrectomy; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007078:Ileal Neoplasms / Q000188:drug therapy / Q000601:surgery; D000068877:Imatinib Mesylate; D007580:Jejunal Neoplasms / Q000235:genetics / Q000601:surgery; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D012186:Retroperitoneal Neoplasms / Q000601:surgery; D012189:Retrospective Studies; D012509:Sarcoma / Q000188:drug therapy / Q000601:surgery*; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D004791:Enzyme Inhibitors; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate