title: Results of the pregnancies with HELLP syndrome.
abstract: In this study, clinical features, developing complications, and results of thirty-six patients, which were followed up in our Obstetrics and Gynecology and Nephrology departments between 1997 and 2001, with the diagnosis of HELLP syndrome were searched retrospectively. The mean age of the cases followed up with diagnosis of HELLP syndrome were 30.2 +/- 5.9 (17-46) years. HELLP syndrome was diagnosed on average in the 32.6 +/- 4.8th (23-41) week of gestations. Seventy percent of the cases were with severe preeclampsia and 30% of the cases were with mild preeclampsia. Eleven cases (30%) were nullipara and twenty-five cases (70%) multipara. The average of arterial systolic blood pressure of the cases were 161.6 +/- 26 mmHg, and that of diastolic blood pressure was 98.5 +/- 16.8 mmHg. In thirteen cases (36%) acute renal failure (ARF), six cases (17%) placenta detachment, two cases disseminate intravascular coagulation (DIC), one case Adult Respiratory Distress Syndrome (ARDS) were developed. In seven cases (19%) intrauterine dead fetuses were detected. In twenty-three cases by cesarian section (64%), in thirteen cases by induction (36%) the pregnancies were terminated in 72 h after diagnosing HELLP syndrome. Birth weights of eleven babies (30%) were below 1500 g. Five of the eleven babies were dead in the neonatal period. Six of the thirteen patients who had ARF were given hemodialysis. Two patients died because of the development of ARF + DIC and ARDS. No predicting factors for the development of HELLP syndrome could be detected, but severe preeclampsia. Therefore we think that preeclamptic pregnancies must be followed up very closely and if HELLP syndrome develops, termination of the pregnancy would be proper as soon as possible.
authors.affiliation: Selçuk University Faculty of Meram Medicine, Department of Obstetrics and Gynecology-Nephrology, Konya, Turkey. celikcet@hotmail.com
authors.forename: Cetin
authors.initials: C
authors.lastname: Celik
authors.forename: Kazim
authors.initials: K
authors.lastname: Gezginç
authors.forename: Lutfullah
authors.initials: L
authors.lastname: Altintepe
authors.forename: H Zeki
authors.initials: HZ
authors.lastname: Tonbul
authors.forename: S Tülin
authors.initials: ST
authors.lastname: Yaman
authors.forename: Cemalettin
authors.initials: C
authors.lastname: Akyürek
authors.forename: Süleyman
authors.initials: S
authors.lastname: Türk
mesh_terms: D000032:Abortion, Therapeutic; D058186:Acute Kidney Injury / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D001724:Birth Weight / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002585:Cesarean Section; D003971:Diastole / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D017359:HELLP Syndrome / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D007226:Infant Mortality; D007231:Infant, Newborn; D008428:Maternal Mortality; D008429:Maternal Welfare; D008875:Middle Aged; D010298:Parity; D011225:Pre-Eclampsia / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy / Q000502:physiology*; D011248:Pregnancy Complications / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D011256:Pregnancy Outcome; D006435:Renal Dialysis; D012128:Respiratory Distress Syndrome / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013599:Systole / Q000502:physiology; D014421:Turkey