Optical-fiber-based Mueller optical coherence tomography.
An optical-fiber-based multichannel polarization-sensitive Mueller optical coherence tomography (OCT) system was built to acquire the Jones or Mueller matrix of a scattering medium, such as biological tissue. For the first time to our knowledge, fiber-based polarization-sensitive OCT was dynamically calibrated to eliminate the polarization distortion caused by the single-mode optical fiber in the sample arm, thereby overcoming a key technical impediment to the application of optical fibers in this technology. The round-trip Jones matrix of the sampling fiber was acquired from the reflecting surface of the sample for each depth scan (A scan) with our OCT system. A new rigorous algorithm was then used to retrieve the calibrated polarization properties of the sample. This algorithm was validated with experimental data. The skin of a rat was imaged with this fiber-based system.
Jiao
Shuliang
S
Optical Imaging Laboratory, Department of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, Texas 77843-3120, USA.
Yu
Wurong
W
Stoica
George
G
Wang
Lihong V
LV
D000818:Animals; D005336:Fiber Optic Technology; D008962:Models, Theoretical; D055100:Optical Fibers; D055095:Optics and Photonics; D051381:Rats; D012867:Skin / Q000033:anatomy & histology; D014054:Tomography