[Current status of reduced-intensity stem cell transplantation; survey in the Kinki area].
The status of reduced-intensity stem cell transplantation (RIST) in the Kinki area was investigated by questionnaires. We sent out questionnaires to 72 institutions and received 51 replies (72.2%). RIST was performed in 16 institutions (31.4%). A total of 91 cases were included of whom approximately 70% were non-remission or advanced hematological malignancies. Various conditioning regimens were used for RIST, most often consisting of fludarabine, busulfan and antithymocte globulin. Acute GVHD developed in 57% of all patients. Relapse or disease progression developed in 42.7% of evaluable patients. The overall survival rate was 54.6%, and 80% of low risk patients were alive at the time of analysis.
Ashida
Takashi
T
Division of Hematology, Nephrology and Rheumatology, Department of Internal Medicine, Kinki University School of Medicine.
Maeda
Yasuhiro
Y
Kanamaru
Akihisa
A
Ichinohe
Tatsuo
T
Yamane
Takahisa
T
Hatanaka
Kazuo
K
Ogawa
Hiroyasu
H
Kobayashi
Yutaka
Y
Hara
Hiroshi
H
Inoue
Tetsuya
T
Sugiyama
Tateo
T
Nagai
Kenichi
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006086:Graft vs Host Disease / Q000517:prevention & control; D019337:Hematologic Neoplasms / Q000628:therapy; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D033581:Stem Cell Transplantation / Q000379:methods* / Q000401:mortality / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D015996:Survival Rate; D019172:Transplantation Conditioning / Q000009:adverse effects / Q000379:methods*