Placement of deep brain stimulators into the subthalamic nucleus or Globus pallidus internus: technical approach.
Deep brain stimulation (DBS) represents a major advance in the treatment of Parkinson's disease (PD). As more neurosurgeons enter this field, technical descriptions of implantation techniques are needed. Here we present our technical approach to subthalamic nucleus (STN) and globus pallidus internus (GPi) DBS implantation, based on 180 STN implants and 75 GPi implants. The essential steps in DBS implantation are magnetic resonance imaging (MRI)-guided stereotactic localization, confirmation of the motor territory of the target nucleus with microelectrode mapping, and intra-operative test stimulation to determine voltage thresholds for stimulation-induced adverse effects. Lead locations are documented by postoperative MRI in all cases.
Starr
Philip A
PA
University of California at San Francisco and San Francisco Veteran's Affairs Medical Center, Moffitt Hospital, San Francisco, CA 94143, USA. starrp@itsa.ucsf.edu
D004421:Dystonia / Q000601:surgery / Q000628:therapy; D004599:Electric Stimulation Therapy / Q000379:methods*; D005917:Globus Pallidus / Q000601:surgery*; D006801:Humans; D019635:Neurosurgical Procedures; D010300:Parkinson Disease / Q000601:surgery* / Q000628:therapy*; D013238:Stereotaxic Techniques; D020531:Subthalamic Nucleus / Q000601:surgery*