[Clinical analysis of 190 cases of outbreak with atypical pneumonia in Guangzhou in spring, 2003].
OBJECTIVE
To study methods of diagnosis and treatment for atypical pneumonia (Severe Acute Respiratory Syndrome), outbreak of the illness in Guangzhou during Jan. - Mar., 2003.


METHODS
190 cases with atypical pneumonia were analyzed, and the cases were admitted in Guangzhou municipal First Hospital and Guangzhou municipal Eighth Hospital.


RESULTS
Patients were infected by close quarters contacting each other. All patients manifest high fever, and accompany by dyspnea, cough, palpitate, weakness, headache and swirl. Other 46 cases were accompanied by diarrhea. Most of patients, manifestation of lungs was negative. Chest X-ray, shadow of lungs were light in beginning, and change to severity slowly or suddenly during 5 - 10 days. Of these cases, 36 cases develop to ARDS and 11 cases died with severity ARDS. Using general antibiotic was of no effect for the illness. Continual positive airway pressure (CPAP) and glucocorticoid was required that can control deprivation of the disease when toxicosis symptom of patients was severity and shadow of lungs diffuse more and more.


CONCLUSIONS
Infectivity of the illness is evidence and spread by airway. Using general antibiotic was of no effect for the illness. Continual positive airway pressure (CPAP) and glucocorticoid are effective for control of the disease.
Zhao
Zi-wen
ZW
Guangzhou Municipal First People's Hospital, Guangzhou 510180, China.
Zhang
Fu-chun
FC
Xu
Min
M
Huang
Kan
K
Zhong
Wei-nong
WN
Cai
Wei-ping
WP
Yin
Chi-biao
CB
Huang
Shao-dan
SD
Deng
Zhe-tong
ZT
Wei
Min
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002681:China; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011175:Positive-Pressure Respiration; D012128:Respiratory Distress Syndrome / Q000209:etiology*; D045473:Severe acute respiratory syndrome-related coronavirus / Q000302:isolation & purification*; D045169:Severe Acute Respiratory Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*
D000900:Anti-Bacterial Agents; D008775:Methylprednisolone