title: Lung, gastric, and soft tissue uptake of Tc-99m MDP and Ga-67 citrate associated with hypercalcemia.
abstract: Metastatic calcifications are associated with chronic renal failure, hyperparathyroidism, metastatic neoplasms, hypervitaminosis D, and hypercalcemia of other origins. Bone scanning agents accumulate within these extraskeletal metastatic calcifications. The authors describe two patients with hypercalcemia associated with Tc-99m MDP uptake in the lungs, stomach, and soft tissues. Ga-67 scintigraphy was also performed and showed increased uptake in the same locations as those of Tc-99m MDP, suggesting the existence of an inflammatory process. Despite adequate treatment, only partial resolution of extraskeletal uptake was observed.
authors.affiliation: Department of Nuclear Medicine, Hôpital Brugmann, Brussels, Belgium. catherine.castaigne@stpierre-bru.be
authors.forename: Catherine
authors.initials: C
authors.lastname: Castaigne
authors.forename: Philippe
authors.initials: P
authors.lastname: Martin
authors.forename: Didier
authors.initials: D
authors.lastname: Blocklet
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000000981:diagnostic imaging; D003238:Connective Tissue / Q000000981:diagnostic imaging*; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D006934:Hypercalcemia / Q000000981:diagnostic imaging*; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013270:Stomach / Q000000981:diagnostic imaging*; D013669:Technetium Tc 99m Medronate
chemical_list: D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate