title: Expression pattern of Siaz gene during the zebrafish embryonic development.
abstract: Siah is a mammalian homolog of Drosophila seven in absentia (SINA). Here we report the identification of a new member of the SINA/Siah gene family. This new gene, designated Siaz, was found in zebrafish, and its product is predicted to share extensive amino acid sequence homology with Drosophila SINA. Siaz is maternally inherited, with zygotic expression in all blastomeres starting at the mid-blastula transition. After the 20-somite stage, Siaz expression occurs in a stage-specific manner in particular regions, including the brain, eye, cranial cavity, otic vesicle, optic chiasm and gut.
authors.affiliation: Department of Biology, College of Natural Sciences Chungnam National University, Daejeon 305-764, South Korea.
authors.forename: Hyunju
authors.initials: H
authors.lastname: Ro
authors.forename: Kyoon E
authors.initials: KE
authors.lastname: Kim
authors.forename: Tae L
authors.initials: TL
authors.lastname: Huh
authors.forename: Sang-Kyu
authors.initials: SK
authors.lastname: Lee
authors.forename: Myungchull
authors.initials: M
authors.lastname: Rhee
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000196:embryology / Q000378:metabolism; D003001:Cloning, Molecular; D005123:Eye / Q000196:embryology / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D015723:Gene Library; D017403:In Situ Hybridization; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000196:embryology; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000235:genetics* / Q000378:metabolism*; D015347:RNA Probes; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012441:Saccharomyces cerevisiae; D017386:Sequence Homology, Amino Acid; D020798:Two-Hybrid System Techniques; D044767:Ubiquitin-Protein Ligases; D015027:Zebrafish / Q000196:embryology*; D000098563:Seven in Absentia Proteins
chemical_list: D009687:Nuclear Proteins; D015347:RNA Probes; D012333:RNA, Messenger; D044767:Ubiquitin-Protein Ligases; D000098563:Seven in Absentia Proteins