title: Theory-based research in schizophrenia.
abstract: OBJECTIVE
  Theoretical models to guide research into schizophrenia.
  
  
  OBJECTIVE
  To review the most commonly used biological and environmental models of schizophrenia.
  
  
  METHODS
  Published literature and research conducted by the author.
  
  
  CONCLUSIONS
  The vulnerability model includes both biological and environmental variables that impact the course of schizophrenia and treatment.
  
  
  RESULTS
  Thus, it may be a useful framework for nursing research examining responses to various psychosocial treatments in schizophrenia.
authors.affiliation: University of Florida, College of Nursing/Health Science Center, Gainesville, FL, USA. lbeebe@nursing.ufl.edu
authors.forename: Lora Humphrey
authors.initials: LH
authors.lastname: Beebe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016294:Models, Nursing; D008960:Models, Psychological; D015403:Nursing Evaluation Research / Q000379:methods*; D009742:Nursing Theory; D010865:Pilot Projects; D011568:Psychiatric Nursing / Q000379:methods*; D012107:Research Design; D012559:Schizophrenia / Q000209:etiology / Q000451:nursing*; D012565:Schizophrenic Psychology; D013315:Stress, Psychological / Q000150:complications / Q000517:prevention & control; D013598:Systems Theory; D013689:Telephone; D016896:Treatment Outcome