title: [Age-related changes in the mucocutaneous junction and the conjunctivochalasis in the lower lid margins].
abstract: OBJECTIVE
  We investigated the age-related changes in the mucocutaneous junction and the conjunctivochalasis at the lower lid margin, and whether there is a correlation between the two or not.
  
  
  METHODS
  Sixty eyes of sixty patients without ocular surface disorders were examined and they were divided into six groups by age (20-29, 30-39, 40-49, 50-59, 60-69 and 70-79 years old) and sex(five males and five females in each age group). The lower lid margins were divided into three parts(the temporal third, the middle third, and the nasal third) and the anteroplacement of the mucocutaneous junction and the conjunctivochalasis were graded 0, 1, 2 and 3.
  
  
  RESULTS
  In each part of the lower lid margins, there were significant age-related increases in both parameters(p < 0.005, p < 0.0001 respectively). Also, the grade of the anteroplacement of mucocutaneous junction increased with the grade of conjunctivochalasis.
  
  
  CONCLUSIONS
  These findings suggest that there is a relationship between the anteroplacement of the mucocutaneous junction and the conjunctivochalasis with aging.
authors.affiliation: Department of Opthalmology, Kyoto Prefectural University of Medicine, 465 Kajiicho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto 602-0841, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Hirotani
authors.forename: Norihiko
authors.initials: N
authors.lastname: Yokoi
authors.forename: Aoi
authors.initials: A
authors.lastname: Komuro
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D003228:Conjunctiva / Q000502:physiology*; D005143:Eyelids / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000502:physiology; D012879:Skin Physiological Phenomena