title: Comparison of I-123 IMP and Ga-67 citrate scintigraphy of malignant melanoma.
abstract: I-123 iodoamphetamine (IMP) and Ga-67 scintigraphy of malignant melanoma were performed to compare the accumulation of these tracers regarding tumor diameter to determine the site of I-123 IMP accumulation and to evaluate the use of I-123 IMP and Ga-67 in postoperative follow-up. The studies involved 44 patients with a definite diagnosis of malignant melanoma during a 10-year period from April 1991 through March 2001. In this study a very high detection rate of 90.9% was obtained for primary foci with I-123 IMP. With Ga-67, the primary site detection rate was 25%. The results suggest that I-123 IMP is superior to Ga-67 with respect to the detection rate of primary site.
authors.affiliation: Department of Radiology, Aichi Medical University, Nagoya, Japan. murata@aichi-med-u.ac.jp
authors.forename: Katsuhito
authors.initials: K
authors.lastname: Murata
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ayakawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Higashi
authors.forename: Pei-Jan
authors.initials: PJ
authors.lastname: Paul Lin
mesh_terms: D000368:Aged; D002951:Citrates / Q000493:pharmacokinetics; D005260:Female; D005708:Gallium / Q000493:pharmacokinetics; D006801:Humans; D020367:Iofetamine / Q000493:pharmacokinetics; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000556:secondary; D008875:Middle Aged; D011182:Postoperative Care; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics
chemical_list: D002951:Citrates; D019275:Radiopharmaceuticals; D020367:Iofetamine; D005708:Gallium; C103850:gallium citrate