title: Current trend in ivermectin usage for scabies.
abstract: Ivermectin, an anti-parasitic agent widely used for onchocerciasis in humans, is emerging as an oral antiscabietic that is as safe and effective as the topical antiscabietics. In the recent reports, all groups of population responded to ivermectin in the treatment of scabies, including immunocompetent, immunocompromised, and other high-risk populations such as individuals with Down's syndrome. This report reviews the efficacy, the mechanism of action, and the safety profile of ivermectin in the treatment of scabies, particularly its utility in crusted scabies and outbreaks of scabies in institutional settings.
authors.affiliation: Will's Eye Hospital, Philadelphia, Pennsylvania, USA.
authors.forename: Anthony F
authors.initials: AF
authors.lastname: Santoro
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rezac
authors.forename: Jason B
authors.initials: JB
authors.lastname: Lee
mesh_terms: D000328:Adult; D000969:Antinematodal Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D002648:Child; D004196:Disease Outbreaks; D006207:Half-Life; D006801:Humans; D007326:Institutionalization; D007559:Ivermectin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D012532:Scabies / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000969:Antinematodal Agents; D007559:Ivermectin