title: [Diffusion tensor MRI of Wallerian degeneration: a case report].
abstract: Diffusion tensor imaging allows a 3D analysis of water molecular motion and an exploration of white matter tracts integrity and orientation. We report a diffusion tensor study of wallerian degeneration of the corticospinal tract following a capsulo-lenticular hemorrhage in a 49-year old man. Reduced anisotropy (loss of fiber coherence) with preserved diffusivity of the damaged corticospinal tract was observed. This highlights the feasibility of diffusion tensor imaging on clinical MR units and its ability to quantify the degree of white matter tract destruction.
authors.affiliation: Département d'Imagerie Morphologique et Fonctionnelle, Université Paris V, Centre Hospitalier Sainte-Anne, Paris, France. oppenheim@chsa.broca.inserm.fr
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
authors.forename: E
authors.initials: E
authors.lastname: Touzé
authors.forename: C
authors.initials: C
authors.lastname: Poupon
authors.forename: J-L
authors.initials: JL
authors.lastname: Mas
authors.forename: J-F
authors.initials: JF
authors.lastname: Méder
mesh_terms: D016880:Anisotropy; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011712:Pyramidal Tracts / Q000473:pathology*; D014855:Wallerian Degeneration / Q000473:pathology*