title: [Studies on the phenolic acid constituents from Chinese medicine "sheng-ma", rhizome of Cimicifuga foetida L].
abstract: OBJECTIVE
  To look for new active constituents from Chinese medicine "Sheng-ma", rhizome of Cimicifuga foetida L.
  
  
  METHODS
  The compounds were separated and purified by chromatography on silica gel and Sephadex LH-20. Their structures were determined by spectral analysis and chemical reaction.
  
  
  RESULTS
  Eight compounds were obtained and identified as cimicifugic acid (1), esculetin (2), caffeic acid methyl ester (3), 4-O-acetyl-caffeic acid (4), sinapic acid (5), caffeic acid (6), ferulic acid (7), isoferulic acid (8).
  
  
  CONCLUSIONS
  Compound 1 is a new compound, and compounds 2-7 were isolated from this plant for the first time.
authors.affiliation: Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China.
authors.forename: Xiao-hong
authors.initials: XH
authors.lastname: Zhao
authors.forename: Di-hua
authors.initials: DH
authors.lastname: Chen
authors.forename: Jian-yong
authors.initials: JY
authors.lastname: Si
authors.forename: Rui-le
authors.initials: RL
authors.lastname: Pan
authors.forename: Lian-gang
authors.initials: LG
authors.lastname: Shen
mesh_terms: D002109:Caffeic Acids / Q000737:chemistry / Q000302:isolation & purification*; D031885:Cimicifuga / Q000737:chemistry*; D003373:Coumaric Acids / Q000737:chemistry / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D010648:Phenylacetates / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry*; D014468:Umbelliferones / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D002109:Caffeic Acids; D003373:Coumaric Acids; D004365:Drugs, Chinese Herbal; D062385:Hydroxybenzoates; D010648:Phenylacetates; D014468:Umbelliferones; C116092:cimicifugic acid; C073734:sinapinic acid; C017616:phenolic acid; C007628:esculetin