title: Electrostatic complexation and photoinduced electron transfer between Zn-cytochrome c and [olyanionic fullerene dendrimers.
abstract: Two dendritic fullerene (DF) monoadducts, 2 and 3, which can carry up to 9 and 18 negative charges, respectively, were examined with respect to electrostatic complexation with Cytochrome c (Cytc). To facilitate comprehensive photophysical investigations, the zinc analogue of Cytc (ZnCytc) was prepared according to a novel, modified procedure. The association of ZnCytc and DF, and consequential photoinduced electron transfer within ZnCytc-DF from the photoexcited protein to the fullerene, was proven by fluorescence spectroscopy and transient absorption spectroscopy. These findings were also supported by circular dichroism as well as by extensive molecular dynamics (MD) simulations.
authors.affiliation: Institut für Organische Chemie Universität Erlangen-Nürnberg Henkestrasse 42, 91054 Erlangen, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Braun
authors.forename: Stefan
authors.initials: S
authors.lastname: Atalick
authors.forename: Dirk M
authors.initials: DM
authors.lastname: Guldi
authors.forename: Harald
authors.initials: H
authors.lastname: Lanig
authors.forename: Michael
authors.initials: M
authors.lastname: Brettreich
authors.forename: Stephan
authors.initials: S
authors.lastname: Burghardt
authors.forename: Maria
authors.initials: M
authors.lastname: Hatzimarinaki
authors.forename: Elena
authors.initials: E
authors.lastname: Ravanelli
authors.forename: Maurizio
authors.initials: M
authors.lastname: Prato
authors.forename: Rudi
authors.initials: R
authors.lastname: van Eldik
authors.forename: Andreas
authors.initials: A
authors.lastname: Hirsch
mesh_terms: D000838:Anions / Q000737:chemistry*; D045304:Cytochromes c / Q000737:chemistry*; D004563:Electrochemistry; D004579:Electron Transport; D037741:Fullerenes / Q000737:chemistry*; D006418:Heme / Q000737:chemistry; D006860:Hydrogen Bonding; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D010777:Photochemistry; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared; D055672:Static Electricity; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
chemical_list: D000838:Anions; D037741:Fullerenes; D011108:Polymers; D006418:Heme; D045304:Cytochromes c; D015032:Zinc