Antibacterial new clerodane diterpenes from the surface of Haplopappus foliosus.
A biologically monitored fractionation of the resinous exudate extract of Haplopappus foliosus DC. is reported. Purification of the two active fractions yielded 2-alpha-hydroxy- cis-cleroda-3,13(Z),8(17)-trien-15-oic acid (1) and 2-alpha-acetoxy- cis-cleroda-3,13(Z),8(17)-trien-15-oic acid (2), two new clerodane diterpenes.
Urzúa
Alejandro
A
Torres
René
R
Mendoza
Leonora
L
Delle Monache
Franco
F
D000890:Anti-Infective Agents / Q000302:isolation & purification*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane; D031206:Haplopappus / Q000737:chemistry*; D008826:Microbial Sensitivity Tests
D000890:Anti-Infective Agents; D004224:Diterpenes; D045785:Diterpenes, Clerodane