Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy).
Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI-HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated.
Bini
C
C
Department of Medicine and Public Health, Section of Legal Medicine, University of Bologna, via Irnerio 49, 40126 Bologna, Italy.
Ceccardi
S
S
Luiselli
D
D
Ferri
G
G
Pelotti
S
S
Colalongo
C
C
Falconi
M
M
Pappalardo
G
G
D022801:Complementarity Determining Regions / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D011110:Polymorphism, Genetic
D022801:Complementarity Determining Regions; D004272:DNA, Mitochondrial