[Prevention of bacteremia from central venous catheters in hemodialysis: value of application of a mixture of rifampicin and protamine at the insertion site].
During the last 8.5 years, authors observed only 3 bacteremias out of 249 catheters in place in different sites corresponding to a total of 10,063 days with central venous catheterization in hemodialysis (0.30/1000 catheter days). This good result seems to be correlated mainly with the preventive application, on catheter insertion-site, of a rifampin and protamine sulphate mixture. This protocol appears worthy to be known because, at the present time, whatever the new preventive strategies, infection rates reported in the literature are generally more consequent and it is necessary to consider all the possibilities of decreasing them.
Montagnac
R
R
Service de néphrologie-hémodialyse, Centre hospitalier de Troyes. richard.montagnac@ch-troyes.fr
Schillinger
F
F
Eloy
C
C
D000287:Administration, Topical; D000328:Adult; D016470:Bacteremia / Q000209:etiology / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011479:Protamines / Q000008:administration & dosage*; D006435:Renal Dialysis; D012293:Rifampin / Q000008:administration & dosage*
D011479:Protamines; D012293:Rifampin