Getting a grip on the CTD of Pol II.
The first structure of a pre-mRNA processing factor bound to heptad repeats from the C-terminal domain of RNA polymerase II is revealed in a crystal of capping guanylyltransferase complexed with a four-repeat phosphopeptide.
Greenleaf
Arno
A
Department of Biochemistry, Duke University, Durham, NC 27710, USA.
D000595:Amino Acid Sequence; D016384:Consensus Sequence; D018360:Crystallography, X-Ray; D009713:Nucleotidyltransferases / Q000737:chemistry / Q000378:metabolism*; D010748:Phosphopeptides / Q000378:metabolism; D017434:Protein Structure, Tertiary; D012319:RNA Polymerase II / Q000737:chemistry*; D020079:Terminal Repeat Sequences; D000098556:mRNA Guanylyltransferases
D010748:Phosphopeptides; D009713:Nucleotidyltransferases; D012319:RNA Polymerase II; D000098556:mRNA Guanylyltransferases