[Effect on dose owing to source displacement in coronary endovascular brachytherapy].
OBJECTIVE
To investigate the effect on the dose distribution of source position displacement with the target region margin in catheter-based 192Ir line source endovascular brachytherapy.


METHODS
Dose rate distribution along longitudinal axes was estimated by the formula recommended by AAPM No.60 and No. 43.


RESULTS
In the two cases of source displacement (1.1 and 5 mm) doses of target region margin was decreased dramatically (at most 53.9% and 565.8% respectively) were compared to that of no source displacement, and the affected range was 6 mm and 9 mm respectively.


CONCLUSIONS
Source displacement will lead to the decrease of dose in target region margin.
Xu
Zhi-yong
ZY
Institute of Radiation Medicine, CAMS, PUMC, Tianjin 300192, China. xzyong12@vip.sina.com
Zhang
Liang-an
LA
Yuan
Shu-yu
SY
Dai
Guang-fu
GF
D000818:Animals; D001918:Brachytherapy / Q000379:methods*; D023903:Coronary Restenosis / Q000532:radiotherapy*; D003331:Coronary Vessels / Q000528:radiation effects*; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D011879:Radiotherapy Dosage
D007496:Iridium Radioisotopes