[Placental site trophoblastic tumor of the uterus after in vitro fertilization. A case report with initial vaginal metastasis].
We report the first case of placental site trophoblastic tumor following in vitro fertilization. A 32-year-old woman presented with a vaginal polyp diagnosed 11 months after a successful fertilization, resulting in the delivery of a term male baby, but followed by persistent amenorrhea. The diagnosis of PSTT was done on examination of the vaginal polyp and the curettage specimen and was confirmed after hysterectomy. The patient was well 30 months later. The value of initial metastases limited to the pelvis and the role of in vitro fertilization in the pathogenesis of the tumor are discussed.
Buénerd
Annie
A
Service d'Anatomie et de Cytologie pathologiques, Hôpital Edouart Herriot, Lyon.
Mathevet
Patrice
P
Gengler
Carole
C
Scoazec
Jean-Yves
JY
Berger
Gérard
G
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D011247:Pregnancy; D018245:Trophoblastic Tumor, Placental Site / Q000209:etiology* / Q000556:secondary; D014594:Uterine Neoplasms / Q000209:etiology* / Q000473:pathology; D014625:Vaginal Neoplasms / Q000556:secondary