title: [Genotyping of HLA-DRB1 by PCR-SSP in Yunnan Lahu ethnic groups].
abstract: OBJECTIVE
  To investigate polymorphism of HLA-DRB1 in Chinese Lahu population in Yunnan.
  
  
  METHODS
  Polymerase chain reaction-sequence specific primers (PCR-SSP) were used to determine HLA-DRB1 genotypes of 110 unrelated healthy Lahu minority people of Yunnan Province.
  
  
  RESULTS
  Sixteen alleles of DRB1 were detected in this study. The results of test showed that the genotype distributions observed were corresponded with the Hardy-Weinberg equilibrium.
  
  
  CONCLUSIONS
  This study has obtained a more comprehensive and accurate data set of the normal allele frequencies of HLA-DRB1 in Chinese Lahu population in Yunnan Province, which may be of significance in the studies on population genetics and disease association.
authors.affiliation: Department of Genetics, Institute of Medical Biology, CAMS, PUMC, Kunming 650118, China.
authors.forename: Kun-xue
authors.initials: KX
authors.lastname: Hong
authors.forename: Qin
authors.initials: Q
authors.lastname: He
authors.forename: Xi-yun
authors.initials: XY
authors.lastname: San
authors.forename: Jian-kun
authors.initials: JK
authors.lastname: Yu
authors.forename: Ke-qin
authors.initials: KQ
authors.lastname: Lin
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Jia-you
authors.initials: JY
authors.lastname: Chu
mesh_terms: D044466:Asian People; D017931:DNA Primers; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods
chemical_list: D017931:DNA Primers; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains