Zonisamide effective for weight loss in women.
Zonisamide (Zonegran), in conjunction with a reduced-calorie diet (deficit of 500 kcal/d), resulted in an additional mean 5-kg (11-pound) weight loss compared with diet alone. This regimen was well-tolerated in obese female patients. Further evaluation of long-term side effects and continued weight loss beyond 32 weeks is needed.
Kim
Caroline S
CS
Department of Family Medicine, University of Virginia Health Sciences Center, Charlottesville, USA. csk3g@virginia.edu