Anaphylaxis induced by pine nuts in two young girls.
Pine nuts are the seeds of Pinus pinea. There are few reported cases of allergy to pine nut. We describe two young girls with anaphylaxis caused by small amounts of pine nuts. Specific IgE to pine nut was demonstrated by skin prick tests and RAST but no IgE to other nuts and pine pollen was detected. The patients had IgE against a pine nut protein band with apparent molecular weights of approximately 17 kDa that could be considered as the main allergen. Our patients were monosensitized to pine nut and the 17-kDa protein could be correlated with the severe clinical symptoms.
Ibáñez
M Dolores
MD
Servicio de Alergia, Hospital Universitario Niño Jesús, Madrid, Spain. dibanezs@medynet.com
Lombardero
Manuel
M
San Ireneo
Mercedes Martinez
MM
Muñoz
M Carmen
MC
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000707:Anaphylaxis / Q000188:drug therapy / Q000209:etiology*; D000799:Angioedema / Q000188:drug therapy / Q000209:etiology; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D004417:Dyspnea / Q000188:drug therapy / Q000209:etiology; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D021184:Nut Hypersensitivity / Q000188:drug therapy / Q000209:etiology*; D009754:Nuts / Q000009:adverse effects*; D028223:Pinus / Q000009:adverse effects*; D012135:Respiratory Sounds / Q000209:etiology
D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D018926:Anti-Allergic Agents; D006634:Histamine H1 Antagonists; D004837:Epinephrine