title: [TNF-alpha in prognosis of a recovery of the spinal marrow function in patients with spinal tuberculosis].
abstract: The TNF-alpha significance in forecasting a degree of recovering of the spinal marrow functions was studied in complicated courses of tuberculous spondylitis in 37 patients with generalized and multiple tuberculosis. The TNF-alpha level in the cerebrospinal fluid was found to be related with a severity of inflammation and of neurological disorders, as well as with a degree of spinal marrow compression and with a speed of regression of postoperative disorders in the spinal marrow. The initial TNF-alpha concentration of > or = 400 pg/ml was indicative of a possibility to ensure a fast regression of postoperative disorders in the spinal marrow, while no complete recovery of spinal-marrow functions was observed in cases the TNF-alpha was < 400 pg/ml.
authors.forename: V V
authors.initials: VV
authors.lastname: Oleĭnik
authors.forename: E I
authors.initials: EI
authors.lastname: Potapenko
authors.forename: O A
authors.initials: OA
authors.lastname: Iakunova
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D020127:Recovery of Function; D014399:Tuberculosis, Spinal / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
chemical_list: D014409:Tumor Necrosis Factor-alpha