Application of peptide nucleic acid (PNA) for detection of transcription factors binding probes.
We designed novel PNA monomer units that could post-synthetically and quantitatively introduce photo-functionalized molecules into PNA oligomers. Designed photo-functionalized PNAs were applicable to wide fields such as genome based analysis. In this study, we applied a photo-functionalized PNA oligomers for the detection of transcription factors binding probes.
Fujimori
Fumihiro
F
Department of Biological Science & Technology, Faculty of Industrial Science & Technology, Tokyo University of Science, Yamazaki, Noda-Shi, Chiba, 278-8510, Japan.
Kitagawa
Fumihiko
F
Abe
Yukiko
Y
Ohori
Youji
Y
Kiyota
Rieko
R
Nakamura
Yushin
Y
Ikeda
Hisafumi
H
Murakami
Yasufumi
Y
D024202:Electrophoretic Mobility Shift Assay; D015335:Molecular Probes; D020135:Peptide Nucleic Acids / Q000737:chemistry* / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism*
D015335:Molecular Probes; D020135:Peptide Nucleic Acids; D014157:Transcription Factors