title: Synthesis of carbocyclic 1-[4-(hydroxymethyl)cyclopent-2-enyl]-1,2,4-triazole-3-carboxamide and its derivatives.
abstract: The synthesis of carbocyclic 1-[4-(hydroxymethyl)cyclopent-2-enyl]-1,2,4-triazole-3-carboxamide (6a) and its derivatives was achieved from triol 10 in excellent overall yield. This route involves a Pd(0)-catalyzed coupling reaction as a key step.
authors.affiliation: Department of Chemistry, Hanyang University, Ansan, Kyunggi-do, Korea.
authors.forename: Gwang-il
authors.initials: GI
authors.lastname: An
authors.forename: Hakjune
authors.initials: H
authors.lastname: Rhee
mesh_terms: D000146:Acids, Carbocyclic / Q000737:chemistry; D000998:Antiviral Agents / Q000737:chemistry*; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D012254:Ribavirin / Q000737:chemistry; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000146:Acids, Carbocyclic; D000998:Antiviral Agents; D003517:Cyclopentanes; D009705:Nucleosides; D014230:Triazoles; C482608:carbocyclic 1-(4-(hydroxymethyl)cyclopent-2-enyl)-1,2,4-triazole-3-carboxamide; C017957:1,2,4-triazole-3-carboxamide; D012254:Ribavirin; D010165:Palladium