Treatment of hookworm infection with 2, 6-Diiodo-4-Nitrophenol.
Single dose(1.0 cc) of 20 % 2, 6-diiodo-4-nitrophenol solution was injected to 82 hookworm infected cases and 79% of them became egg-negative within 2-3 weeks after the injection. Mild to severe local pain were experienced for several minutes in all cases. Two cases complained of paralysis of the arms of the same side. The tablet of the same formula was given orally to 21 cases for 1-4 days. The 2-4 day course with 360 mg/day were enough to eliminate the parasite, and showed no systemic side effects.
Soh
Chin Thack
CT
Department of Parasitology, Yonsei University College of Medicine, Seoul, Korea.
Cho
Moo Joon
MJ
Rho
Yong Hee
YH
Lee
Jae Heung
JH