title: Studies of intramolecular cyclizations of N-acyliminium ions derived from acyclic ketones: unanticipated stereochemical and structural results.
abstract: [reaction: see text] Intramolecular cyclizations of a series of (E)- and (Z)-olefinic acyclic ketone-derived N-acyliminium ions have been studied. It has been found that both the course of the reaction and the stereochemistry of the products are critically dependent upon the tether length and olefin geometry of the cyclization substrate.
authors.affiliation: Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
authors.forename: Wenchun
authors.initials: W
authors.lastname: Chao
authors.forename: Jacob H
authors.initials: JH
authors.lastname: Waldman
authors.forename: Steven M
authors.initials: SM
authors.lastname: Weinreb
mesh_terms: D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007659:Ketones