Deformability and enzymes activities of red blood cells in hemodialysed and peritoneal dialysed patients with chronic renal disease.
These studies were focused on the influence of two treatment methods of patients with chronic renal disease on RBC deformability. In peritoneal dialysed-patients (PD) erythrocytes exhibited a decrease in their deformability as compared to control subjects whereas this parameter in RBC deriving from hemodialysed patients (HD) was not altered. The alleviating effect of plasma components on deformability of erythrocytes was confirmed after the isolation of a pure faction of these cells as the parameter became worse. The activity of studied enzymes: acetylcholinesterase (Ache), dehydrogenase glucose-6-phosphate (G-6-PD) and glutathione reductase (GR) maintained their physiological values in both dialysis groups.
Nowak-Piszczek
Ewa
E
Department of Hematology and Toxicology, Institute of Zoology, Jagiellonian University, Ingardena 6, 30-060 Cracow, Poland.
Wyrwicz
Grazyna
G
Dabrowski
Zbigniew
Z
Smoleński
Olgierd
O
Spodaryk
Krzysztof
K
D000110:Acetylcholinesterase / Q000378:metabolism; D016022:Case-Control Studies; D004907:Erythrocyte Deformability; D004912:Erythrocytes / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D006435:Renal Dialysis / Q000009:adverse effects*
D005954:Glucosephosphate Dehydrogenase; D005980:Glutathione Reductase; D000110:Acetylcholinesterase