title: A new class of spermidine-derived alkaloids.
abstract: [structure: see text] Four new alkaloids, dovyalicins A-D, were isolated from Dovyalis macrocalyx. Their structures were established by two-dimensional COSY, NOESY, HSQC, and HMBC NMR experiments as well as chiroptical methods. The compounds, possessing spermidine as part of a perhydro-1,5-diazocine or a perhydro-1,4-diazepine moiety, constitute a new group of polyamine-derived alkaloids.
authors.affiliation: Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
authors.forename: Dan
authors.initials: D
authors.lastname: Staerk
authors.forename: Matthias
authors.initials: M
authors.lastname: Witt
authors.forename: Hellen A
authors.initials: HA
authors.lastname: Oketch-Rabah
authors.forename: Jerzy W
authors.initials: JW
authors.lastname: Jaroszewski