[Genetic polymorphism of 9 STR loci in Han nation population in Shandong Province].
OBJECTIVE
To study genetic polymorphism of 9 STR loci in Han nation population in Shangdong Province.


METHODS
We investigated 100 unrelated individuals of Han nation population in Shandong Province and studied their genetic distribution of 9 STR loci and Amelogenin locus. Primers of 10 loci were labeled with the NHS-ester fluorescent dye 5-FAM (blue), Joe (green) or NED (yellow). The data of Han nation population were generated by multiple amplification and subjected to GeneScan, genotype and genetic distribution analysis.


RESULTS
83 alleles and 220 genotypes were observed, with the corresponding frequency of 0.0050-0.4050 and 0.0100-0.2100. The average of heterozygosity was 0.7778, the accumulated discrimination power was 0.9999. The accumulated probability of exclusion paternity was 0.9999. The polymorphism information content was 0.5823-0.8396.


CONCLUSIONS
Chi-Square test indicated that the distribution of genotypes agreed with Hardy-Weinberg equilibrium.
Zhu
Bo-feng
BF
National Laboratory of Forensic Sciences, Xi'an Jiaotong University, Xi'an 710061, China. zhubofeng7372@sina.com
Lü
Gui-ping
GP
Shen
Chun-mei
CM
Yao
Gui-fa
GF
Tian
Ying-fang
YF
Li
Tao
T
Wang
Zhen-yuan
ZY
D000483:Alleles; D002681:China / Q000208:ethnology; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics; D005838:Genotype; D006801:Humans; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D020080:Tandem Repeat Sequences
D005819:Genetic Markers