title: Effects of zinc deficiency and supplementation on some hematologic parameters of rats performing acute swimming exercise.
abstract: The aim of the study was to investigate how zinc deficiency and supplementation effect some hematologic parameters of rats performing swimming exercise. Forty adult male Spraque-Dawley rats were divided into 4 groups, zinc deficient swimming group (Group 1, n=10, zinc supplemented swimming group (Group 2, n=10), swimming control group (Group 3, n=10), and control group (Group 4, n=10). Blood samples were taken by decapitation and analyzed for the determination of erythrocyte, hemoglobin level, hematocrit, leukocyte, lymphocyte, platelet count and plasma zinc level at the end of the 4 week experiment. Erythrocyte count of group 1 was the lowest whereas erythrocyte count in group 3 was significantly lower than that in group 2 and 4 (p<0.05). Hemoglobin level of group 1 was significantly lower than that of groups 2 and 4 (p<0.05). Hematocrit was significantly lower in both group 1 and group 3 than both groups 2 and 4 (p<0.05). Lymphocyte count in group 2 was significantly higher than in all other groups (p<0.05). Platelet counts in group 2 was significantly lower than in all other groups (p<0.05). Our findings suggest that zinc deficiency effects the hematologic parameters mentioned negatively whereas zinc supplementation has a positive influence.
authors.affiliation: Department of Physiology, Meram Medical School of Selçuk University, Konya, Turkey. baltaci@selcuk.edu.tr
authors.forename: Abdulkerim Kasim
authors.initials: AK
authors.lastname: Baltaci
authors.forename: Kursat
authors.initials: K
authors.lastname: Ozyurek
authors.forename: Rasim
authors.initials: R
authors.lastname: Mogulkoc
authors.forename: Erdal
authors.initials: E
authors.lastname: Kurtoglu
authors.forename: Esma
authors.initials: E
authors.lastname: Oztekin
authors.forename: Aylin
authors.initials: A
authors.lastname: Kul
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D004906:Erythrocyte Count; D004909:Erythrocyte Indices / Q000187:drug effects*; D006400:Hematocrit; D006454:Hemoglobins / Q000187:drug effects; D007958:Leukocyte Count; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D010976:Platelet Count; D051381:Rats; D017207:Rats, Sprague-Dawley; D013550:Swimming / Q000502:physiology*; D015032:Zinc / Q000097:blood / Q000172:deficiency* / Q000494:pharmacology*
chemical_list: D006454:Hemoglobins; D015032:Zinc