Superficial keratectomy with mitomycin-C for the treatment of Salzmann's nodules.
OBJECTIVE
To evaluate the success of treatment and prevention of recurrence of Salzmann's nodules by superficial keratectomy with intraoperative mitomycin-C (MMC).


METHODS
Price Vision Group, Indianapolis, Indiana, USA.


METHODS
This retrospective consecutive case series comprised 30 eyes of 25 patients who had superficial keratectomy with MMC between January 1997 and June 2000 at a large tertiary-care center.


RESULTS
Twenty-four patients reported improvement in their symptoms. The remaining patient lost 1 line of visual acuity. Ninety-seven percent of eyes maintained or improved best corrected visual acuity. No patient had a recurrence of Salzmann's nodular degeneration over a mean follow-up of 28 months +/- 15 (SD) (range 4.0 days to 4.1 years).


CONCLUSIONS
Superficial keratectomy with MMC appears to be a valid and safe method for treating and preventing the recurrence of Salzmann's nodular degeneration.
Bowers
Patrick J
PJ
Price Vision Group, Indianapolis, Indiana, USA.
Price
Marianne O
MO
Zeldes
Steven S
SS
Price
Francis W
FW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002921:Cicatrix / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003316:Corneal Diseases / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use*; D019384:Nucleic Acid Synthesis Inhibitors / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity
D019384:Nucleic Acid Synthesis Inhibitors; D016685:Mitomycin