title: [Inhibition of remineralization by EDTA-soluble phosphate protein in dentin].
abstract: OBJECTIVE
  To investigate the effect of removing EDTA-soluble phosphate protein in dentin on the later remineralization for the purpose of better understanding of mechanism of dentin phosphate proteins on dentin mineralization.
  
  
  METHODS
  To remove soluble phosphate protein by EDTA dissolution, then the remineralization rate was monitored by a constant composition crystal growth technique. The results were compared with those from the normal dentin and the dentin partially demineralized by acetic acid.
  
  
  RESULTS
  Faster remineralization rates were found with dentin demineralized by EDTA (0.5 and 2 h) compared with normal dentin powder, while a slower rate was found with dentin demineralized by acetic acid. The increase of remineralization rate by removing phosphate protein from dentin was 100% more at 200 min after the start of the reaction.
  
  
  CONCLUSIONS
  EDTA-soluble phosphate protein in dentin has a great potential to inhibit remineralization.
authors.affiliation: Department of Stomatology, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Yu
authors.forename: Xue-jun
authors.initials: XJ
authors.lastname: Gao
authors.forename: Wan-chun
authors.initials: WC
authors.lastname: Chen
authors.forename: Dao-dan
authors.initials: DD
authors.lastname: Liu
mesh_terms: D003739:Dental Cementum / Q000737:chemistry* / Q000378:metabolism; D003804:Dentin / Q000737:chemistry; D004492:Edetic Acid; D006801:Humans; D010750:Phosphoproteins / Q000032:analysis / Q000502:physiology*; D017001:Tooth Demineralization / Q000378:metabolism; D014089:Tooth Remineralization
chemical_list: D010750:Phosphoproteins; D004492:Edetic Acid