title: Disappearance of the Brugada-type electrocardiogram after surgical castration: a role for testosterone and an explanation for the male preponderance.
abstract: We describe two cases of asymptomatic Brugada syndrome that displayed a persistent ECG manifestation, but in which the typical ECG pattern disappeared following surgical castration for prostate cancer. These facts suggest a possible association between manifestation of the Brugada-type ECG pattern and testosterone.
authors.affiliation: Department of Clinical Studies, Radiation Effects Research Foundation, Nagasaki University School of Medicine, Nagasaki, Japan. mikan@net2.nagasaki-u.ac.jp
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Matsuo
authors.forename: Masazumi
authors.initials: M
authors.lastname: Akahoshi
authors.forename: Shinji
authors.initials: S
authors.lastname: Seto
authors.forename: Katsusuke
authors.initials: K
authors.lastname: Yano
mesh_terms: D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D012737:Sex Factors; D013577:Syndrome; D013739:Testosterone / Q000502:physiology*
chemical_list: D013739:Testosterone