Specific IgG antibody responses in experimental cat metagonimiasis.
In order to observe the feasibility of serologic diagnosis of metagonimiasis, saline extracts of metacercariae and 4-week old adults were prepared. Sera from 25 experimentally infected cats were collected from 3 days to 12 weeks after infection. Their levels of specific IgG antibody were measured by ELISA together with 3 sera from non-infected cats. Specific IgG antibody levels began to rise in 7 days after infection, reached their peak in 2-4 weeks and made a plateau thereafter. Cats infected with hundreds of adult worms showed minimal rise of the antibody level. Adult antigen was superior to metacercarial antigen in detecting the specific IgG antibody.
Cho
Seung Yull
SY
Department of Parasitology, College fo Medicine, Chung-Ang University, Seoul, Korea.
Kim
Suk Il
SI
Kang
Shin Yong
SY