title: Transcutaneous ultrasound-facilitated coronary thrombolysis during acute myocardial infarction.
abstract: In preclinical experiments, the combination of transcutaneous, low-frequency ultrasound and thrombolytic therapy has shown improved patency rates over thrombolytics alone. A total of 25 patients with myocardial infarction were treated with a thrombolytic agent and adjunctive transcutaneous ultrasound. No unanticipated major adverse events were observed.
authors.affiliation: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
authors.forename: Mauricio G
authors.initials: MG
authors.lastname: Cohen
authors.forename: Enrique
authors.initials: E
authors.lastname: Tuero
authors.forename: Jorge
authors.initials: J
authors.lastname: Bluguermann
authors.forename: Rubén
authors.initials: R
authors.lastname: Kevorkian
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Berrocal
authors.forename: Oscar
authors.initials: O
authors.lastname: Carlevaro
authors.forename: Eduardo
authors.initials: E
authors.lastname: Picabea
authors.forename: Michael P
authors.initials: MP
authors.lastname: Hudson
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Siegel
authors.forename: Lori
authors.initials: L
authors.lastname: Douthat
authors.forename: Adam B
authors.initials: AB
authors.lastname: Greenbaum
authors.forename: Debra
authors.initials: D
authors.lastname: Echt
authors.forename: W Douglas
authors.initials: WD
authors.lastname: Weaver
authors.forename: Liliana R
authors.initials: LR
authors.lastname: Grinfeld
mesh_terms: D003131:Combined Modality Therapy; D017023:Coronary Angiography; D003326:Coronary Circulation; D004562:Electrocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D000077785:Tenecteplase; D015912:Thrombolytic Therapy / Q000009:adverse effects; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014464:Ultrasonic Therapy / Q000009:adverse effects / Q000379:methods
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; C087896:reteplase; D010959:Tissue Plasminogen Activator; D000077785:Tenecteplase