Inherited platelet disorders.
Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used in clinical practice to manage these conditions.
Hayward
Catherine P M
CP
McMaster University and the Hamilton Regional Laboratory Medicine Program, 1200 Main Street West, HSC Room 2N31, Hamilton, ON L8N 3Z5, Canada. haywrdc@mcmaster.ca
D025861:Blood Coagulation Disorders, Inherited / Q000175:diagnosis / Q000628:therapy; D001791:Blood Platelet Disorders / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000235:genetics