[Oral chemolysis of uric acid stones].
Oral chemolysis of uric acid stones was performed retrospectively. Twenty-one patients with upper urinary uric acid stones were given alkaline citrate (Uralyt-U) orally. In the case of hyperuicemia, allopirinol was combined. In 11 out of 15 patients (73.3%) treated with oral chemolysis alone, stones were dissolved. In 4 out of 6 cases (66.7%) combined with extracorporeal shock-wave lithotripsy, administration of alkaline citrate shortened the period to be stone-free. In conclusion, we successfully treated 15 out of 21 cases (71.4%) with the administration of alkaline citrate.
Honda
Masahito
M
Department of Urology, Osaka Police Hospital.
Yamamoto
Keisuke
K
Momohara
Chikahiro
C
Komori
Kazuhiko
K
Takada
Tuyoshi
T
Fujioka
Hideki
H
D000284:Administration, Oral; D000493:Allopurinol / Q000627:therapeutic use; D019343:Citric Acid / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D006801:Humans; D033461:Hyperuricemia / Q000150:complications / Q000188:drug therapy; D008096:Lithotripsy; D012189:Retrospective Studies; D016896:Treatment Outcome; D014527:Uric Acid / Q000032:analysis*; D014545:Urinary Calculi / Q000737:chemistry / Q000150:complications / Q000628:therapy*
D014527:Uric Acid; D019343:Citric Acid; D000493:Allopurinol