title: Increased incidence of pneumococcal bloodstream infections.
abstract: Pneumococcal bloodstream infections in pediatric patients rose from 3.6 to 14.8 episodes per 100,000 from 1986 to the year 2000 (P < 0.001) in a population of approximately 650,000 inhabitants (16% <16 years of age). Incidence in the group <24 months of age increased from 7.4 to 78.6 episodes per 100,000 per year (P < 0.001). Overall 75% of the serogroups are included in the new heptavalent vaccine.
authors.affiliation: Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Rodríguez-Créixems
authors.forename: Juan
authors.initials: J
authors.lastname: Bertó
authors.forename: Patricia
authors.initials: P
authors.lastname: Muñoz
authors.forename: Roberto
authors.initials: R
authors.lastname: Alonso
authors.forename: Luis
authors.initials: L
authors.lastname: Alcalá
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000900:Anti-Bacterial Agents; D016470:Bacteremia / Q000175:diagnosis / Q000453:epidemiology*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D016014:Linear Models; D008297:Male; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000008:administration & dosage; D011336:Probability; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D015996:Survival Rate; D014611:Vaccination / Q000592:standards / Q000639:trends
chemical_list: D000900:Anti-Bacterial Agents; D022242:Pneumococcal Vaccines