title: [Immediate intraoral adaptation of mandibular advancing appliances of thermoplastic material for the treatment of obstructive sleep apnea-hypopnea syndrome].
abstract: OBJECTIVE
  To appraise the effect of immediate intraoral adaptation of mandibular advancing appliances (MAA) consisting of thermoplastic material for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS).
  
  
  METHODS
  45 patients with OSAHS was treated with MAA that was directly moulded intraorally before sleep. Polysomnography (PSG) was performed and questionnaires recorded prior to and 4 weeks after treatment with MAA.
  
  
  RESULTS
  The efficiency of MAA for OSAHS was 82%. The medial apnea-hypopnoea index decreased from 38 +/- 22 to 11 +/- 9 events per hour (P < 0.001); the medial duration of apnea decreased from 22 +/- 8 to 15 +/- 11 second (P < 0.001); the minimum SaO(2) increased from (72 +/- 11)% to (83 +/- 9)% (P < 0.001), and the medial snore index decreased from 304 +/- 105 to 108 +/- 113 events per hour (P < 0.001). The patients' daytime sleepiness was alleviated, and the majority of the patients could acclimatize themselves to MAA in 3 to 7 days.
  
  
  CONCLUSIONS
  The MAA consisting of thermoplastic material improved OSAHS. It is immediately adaptable and less expensive, and should be considered as a feasible medical treatment.
authors.affiliation: Department of Respiratory Diseases, PLA General Hospital, Beijing 100853, China.
authors.forename: Yu-zhu
authors.initials: YZ
authors.lastname: Li
authors.forename: Feng-ying
authors.initials: FY
authors.lastname: Hao
authors.forename: Gui-qing
authors.initials: GQ
authors.lastname: Jin
authors.forename: You-ning
authors.initials: YN
authors.lastname: Liu
mesh_terms: D000202:Activator Appliances; D000328:Adult; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008875:Middle Aged; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000097:blood / Q000628:therapy*; D012913:Snoring / Q000628:therapy*; D016896:Treatment Outcome