title: An ultrastructural investigation in stomach epithelial cells of mice during pregnancy and early lactation.
abstract: In this study, stomach epithelial cells from adult nonpregnant, pregnant lactating mice were examined by histochemical, immunohistochemical and ultrastructural methods. Tissue samples taken from different groups were stained with haematoxylin-eosin and PAS-alcian blue and semithin sections were stained with toluidin blue for light microscopic examination. For ultrastructural examination ultrathin sections were stained with uranyl acetate and lead citrate. Additionally, by applying immunoperoxidase method, the distribution of EGF receptors of all groups was studied. We concluded that in the pregnant mice, stomach surface had lower mucus than the nonpregnant group. The acid content was balanced in active and inactive parietal cells. Examination results of lactating mice were similar to the results obtained from nonpregnant and pregnant mice.
authors.affiliation: Gazi University, Faculty of Medicine, Department of Histology and Embriology, 06510 Beşevler Ankara, Turkey. ozogulc@med.gazi.edu.tr
authors.forename: Candan
authors.initials: C
authors.lastname: Ozogul
authors.forename: Ece
authors.initials: E
authors.lastname: Lakse
authors.forename: Cigdem
authors.initials: C
authors.lastname: Elmas
authors.forename: Deniz
authors.initials: D
authors.lastname: Erdoğan
mesh_terms: D000818:Animals; D066246:ErbB Receptors / Q000502:physiology; D005260:Female; D005753:Gastric Mucosa / Q000502:physiology / Q000648:ultrastructure*; D007774:Lactation / Q000502:physiology*; D051379:Mice; D009093:Mucus / Q000378:metabolism; D011247:Pregnancy; D013270:Stomach / Q000166:cytology / Q000648:ultrastructure
chemical_list: D066246:ErbB Receptors