title: [Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps].
abstract: OBJECTIVE
  To investigate the role of chloride channel ClC-2 and ClC-3 in human nasal polyps.
  
  
  METHODS
  Two chloride channels ClC-2 and ClC-3 were studied in 27 cases of nasal polyps with immunochemistric staining.
  
  
  RESULTS
  Nasal polyps revealed strong positive staining of ClC-2 and ClC-3, the ClC-2 and ClC-3 proteins localized mainly in epithelial cells, sub-epithelial mucous glands without significant distinction. The number of positive cells of ClC-2 and ClC-3 are 17.6 +/- 6.33 and 23.49 +/- 6.14.
  
  
  CONCLUSIONS
  The chloride channels ClC-2 and ClC-3 may play a role in the formation of nasal polyps.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing Institute of Otolaryngology, Beijing 100005.
authors.forename: Huabin
authors.initials: H
authors.lastname: Li
authors.forename: Demin
authors.initials: D
authors.lastname: Han
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
authors.forename: Erzhong
authors.initials: E
authors.lastname: Fan
authors.forename: Zhongyan
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000328:Adult; D018118:Chloride Channels / Q000096:biosynthesis*; D004847:Epithelial Cells / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism*
chemical_list: D018118:Chloride Channels; C115376:ClC-3 channel