title: Platelet substitutes in the management of thrombocytopenia.
abstract: A variety of agents can improve hemostasis and reduce blood loss caused or exacerbated by congenital or acquired defects in platelet number of function. This review discusses several available approaches for the practicing clinician to reduce bleeding (diffuse or localized) in this clinical setting.
authors.affiliation: Department of Blood Research, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910-7500, USA. thomas.reid@na.amedd.army.mil
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Reid
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Rentas
authors.forename: Lloyd H
authors.initials: LH
authors.lastname: Ketchum
mesh_terms: D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects; D019468:Disease Management; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D013921:Thrombocytopenia / Q000097:blood / Q000188:drug therapy* / Q000628:therapy; D014014:Tissue Adhesives
chemical_list: D000933:Antifibrinolytic Agents; D006490:Hemostatics; D014014:Tissue Adhesives