Haemoglobin concentration and prognosis in new cases of heart failure.
Anaemia is common in severe chronic heart failure and is reported to be a predictor of death. We investigated 552 patients (median age 76 years, range 29-95; 54% men [n=296]), in whom the duration of heart failure was sufficiently short that it would be unlikely to affect haemoglobin concentrations. By contrast with studies in established chronic heart failure, haemoglobin was not independently associated with prognosis when age and serum creatinine concentration were included in the analysis. The adverse effects of anaemia on survival might be a consequence of chronic heart failure rather than a separate process causing disease progression.
Kalra
Paul R
PR
National Heart and Lung Institute, Imperial College School of Medicine, London, UK. p.kalra@imperial.ac.uk <p.kalra@imperial.ac.uk>
Collier
Timothy
T
Cowie
Martin R
MR
Fox
Kevin F
KF
Wood
David A
DA
Poole-Wilson
Philip A
PA
Coats
Andrew J S
AJ
Sutton
George C
GC
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000097:blood / Q000175:diagnosis; D002303:Cardiac Output, Low / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis / Q000401:mortality; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D016019:Survival Analysis
D006454:Hemoglobins; D003404:Creatinine