Histopathologic and scanning electron microscope examination of the nail and hair in chronic mucocutaneous candidiasis.
The case of a 4-year-old boy with chronic mucocutaneous candidiasis is reported. Nail sections stained with periodic acid-Schiff and Grocott-Gomori methenamine-silver showed pseudohyphae running haphazardly within the nail. Scanning electron microscopy showed hyphae penetrating into the nail plate and the hair shaft.
Liu
Jie
J
Department of Dermatology, Third Hospital, Peking University, Beijing, China 100 083. Jieliu1975@hotmail.com
Lei
Pengcheng
P
D001707:Biopsy, Needle; D002178:Candidiasis, Chronic Mucocutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D002675:Child, Preschool; D005500:Follow-Up Studies; D006197:Hair / Q000473:pathology* / Q000648:ultrastructure*; D006801:Humans; D007150:Immunohistochemistry; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D008855:Microscopy, Electron, Scanning; D009262:Nails / Q000473:pathology* / Q000648:ultrastructure*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
D017964:Itraconazole