title: Which tissue adhesive for wounds?
abstract: We studied the three available tissue adhesives comparing their ease of technique, wound healing, satisfaction, merits and complications when treating childhood lacerations. Children presenting with uncomplicated wounds <2.5cm and <6h since the injury were studied. There were 17 children in each group. Results were compared for the individual tissue adhesive and the technique-contact and non-contact. The application was considered pain free in 82% of the non-contact technique and 56% for the contact technique-pain in 18 and 44%, respectively (P=0.062). Parents were satisfied in 88 and 94% for the contact and non-contact techniques, respectively (P=0.505) and the authors in 76 and 94% (P=0.119). The glove stuck to the wound in nine instances and was damaged once while breaking the container. The scab persisted in all scalp applications for 9-25 days. The adhesive effect was similar in all three. Indermil was considered to be the best among the three. Non-contact, droplet instillation (rather than contact application as was suggested for Dermabond and Histoacryl) was felt more comfortable.
authors.affiliation: Department of Paediatric Accident and Emergency, Royal Hospital for Sick Children, Yorkhill, G3 8SJ, Scotland, Glasgow, UK. nanjappachetty.doraiswamy@yorkhill.scot.nhs.uk
authors.forename: N V
authors.initials: NV
authors.lastname: Doraiswamy
authors.forename: H
authors.initials: H
authors.lastname: Baig
authors.forename: S
authors.initials: S
authors.lastname: Hammett
authors.forename: M
authors.initials: M
authors.lastname: Hutton
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D014945:Wound Healing; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D014014:Tissue Adhesives