Ampicillin, gentamicin and teicoplanin as antimicrobial therapy for recurrent Streptococcus agalactiae and Enterococcus faecalis endocarditis in an intravenous drug abuser with HIV infection.
Infective endocarditis associated with human immunodeficiency virus (HIV) infection occurs almost exclusively in intravenous (i.v.) drug users and usually involves the tricuspid valve, with an increased mortality rate among patients with a severe degree of immunosuppression. The first reported case of recurrent tricuspid endocarditis sustained by Streptococcus agalactiae and Enterococcus faecalis in an i.v. drug addict during HIV infection is presented. Antimicrobial therapy with i.v. ampicillin, gentamicin and teicoplanin led to complete clinical and echocardiographical recovery.
Calza
Leonardo
L
Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna, S. Orsola Hospital, Bologna, Italy. malinf@med.unibo.it
Manfredi
Roberto
R
Marinacci
Ginevra
G
Fortunato
Lorenza
L
Chiodo
Francesco
F
D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000209:etiology; D013293:Enterococcus faecalis / Q000187:drug effects*; D005839:Gentamicins / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications*; D006349:Heart Valve Diseases / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008297:Male; D013292:Streptococcus agalactiae / Q000187:drug effects*; D015819:Substance Abuse, Intravenous / Q000150:complications*; D017334:Teicoplanin / Q000627:therapeutic use*; D014261:Tricuspid Valve / Q000187:drug effects / Q000382:microbiology
D005839:Gentamicins; D017334:Teicoplanin; D000667:Ampicillin