title: Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis.
abstract: The new drug niclofolan (bayer 9015, Bilevon), 5,5'-dichloro-2,2'-dihydroxy-3, 3'-dinitrobiphenyl, has been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.
authors.affiliation: Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University, Seoul, Korea.
authors.forename: Han Jong
authors.initials: HJ
authors.lastname: Rim
authors.forename: Myung Se
authors.initials: MS
authors.lastname: Kim
authors.forename: Joung Hwan
authors.initials: JH
authors.lastname: Ha
authors.forename: Dong Shik
authors.initials: DS
authors.lastname: Chang