[The mechanisms of a new plant lectin FRIL from dolichos lablab that preserves quiescent hematopoietic stem cells in suspension culture].
Lectins, proteins that bind sugar moieties of glycolipids and glycoproteins, occur in all organisms and are especially abundant in many plants. Plant lectins probably have multiple roles related to their ability to act as recognition molecules. Here we present a review on the biological characterization of a new plant lectin in red kidney bean named Flt3 receptor-interacting lectin(FRIL), and focus on the mechanisms that FRIL can preserve quiescent hematopoietic stem cells in suspension culture.
Xie
Chao
C
Beijing Institute of Trasfusion, Beijing 100850.
Pei
Xue-Tao
XT
D000818:Animals; D002478:Cells, Cultured; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000502:physiology*; D006801:Humans; D037241:Mannose-Binding Lectins / Q000494:pharmacology* / Q000502:physiology; D037121:Plant Lectins / Q000494:pharmacology* / Q000502:physiology
C117675:FRIL protein, Dolichos lablab; D037241:Mannose-Binding Lectins; D037121:Plant Lectins