Voltammetric investigation of diethylstilbestrol.
In this work electrooxidation of diethylstilbestrol (DES) was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) using a glassy carbon (GC) electrode. It was statistically shown that both methods could be used for the determination of DES in the concentration range of 2 x 10(-5)-6 x 10(-4) M by CV and 1 x 10(-5)-1 x 10(-3) M in methanol (MeOH) and 4 x 10(-5)-6 x 10(-4) M in acetonitrile (ACN) by DPV and both of the methods could be applied to human serum. A mechanism was proposed about the electrooxidation of this substance.
Biryol
Inci
I
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06 100, Ankara, Turkey. biryol@pharmacy.ankara.edu.tr
Salci
Bülent
B
Erdik
Ender
E
D004054:Diethylstilbestrol / Q000097:blood* / Q000737:chemistry; D004563:Electrochemistry; D010084:Oxidation-Reduction; D015203:Reproducibility of Results
D004054:Diethylstilbestrol