Cognitive, behavioral, and psychiatric symptoms in two children with agenesis of the corpus callosum: case report.
OBJECTIVE
To report two children, with normal intelligence, referred for evaluation of complex cognitive, behavioral, and psychiatric problems, in which Agenesis of Corpus Callosum (ACC) was an incidental finding.


METHODS
Case descriptions are used and a comprehensive differential diagnosis made with previous diagnoses of partial complex seizures (PCS), psychosis, anxiety, attention deficit hyperactivity disorder (ADHD), and behavior disorder.


RESULTS
Due to the presence of multiple biopsychosocial interactions a multimodal intervention including pharmacological, behavioral, psychotherapeutic, and social approaches was implemented, with good results.


CONCLUSIONS
These cases underscore the importance of conducting a comprehensive neuropsychiatric evaluation in children with severe behavior problems and other confusing symptoms. Since the incidence of ACC in behaviorally disturbed children, with normal intelligence, is unknown, physicians must accept that a reasonable degree of suspicion is warranted. Further studies are needed to facilitate physicians' awareness.
Párraga
Humberto C
HC
Fourth Street Clinic, Springfield, Illinois 62703, USA.
Párraga
Marianela I
MI
Jensen
Alicia R
AR
D061085:Agenesis of Corpus Callosum; D002648:Child; D002653:Child Behavior Disorders / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D003072:Cognition Disorders / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D003337:Corpus Callosum / Q000503:physiopathology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male