title: Synthesis and biological activity of adenophostin derivatives as IP3 receptor ligands.
abstract: The three derivatives of adenophostin A, which were the C-glycosidic analogs 3a and 3b, and the 5'-phenyl analog 4, were designed and synthesized as efficient IP3 receptor ligands.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shuto
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mochizuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Abe
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kondo
authors.forename: Akira
authors.initials: A
authors.lastname: Matsuda
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D015220:Calcium Channels / Q000187:drug effects* / Q000378:metabolism; D053496:Inositol 1,4,5-Trisphosphate Receptors; D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear / Q000187:drug effects* / Q000378:metabolism
chemical_list: D015220:Calcium Channels; D053496:Inositol 1,4,5-Trisphosphate Receptors; D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear; C085029:adenophostin A; D000241:Adenosine