The cysteinyl leukotriene receptors.
The cysteinyl leukotriene (CysLT) receptors are putative 7 transmembrane spanning G protein-coupled receptors (GPCRs) of the rhodopsin subfamily of GPCRs. Two human and mouse CysLT receptors have been molecularly cloned and characterized. The properties of these receptors agrees well with previous pharmacological CysLT agonist and antagonist characterizations of the CysLT receptors.
Evans
Jilly F
JF
Pharmacology Department, Merck Research Laboratories, Merck & Co, Inc, 770 Sumneytown Pike, West Point, PA 19486, USA. jilly_evans@merck.com
D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D006801:Humans; D020024:Leukotriene Antagonists; D015289:Leukotrienes / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008969:Molecular Sequence Data; D015394:Molecular Structure; D018077:Receptors, Leukotriene / Q000235:genetics / Q000378:metabolism*; D012243:Rhodopsin / Q000737:chemistry / Q000378:metabolism; D016415:Sequence Alignment
D020024:Leukotriene Antagonists; D015289:Leukotrienes; D008565:Membrane Proteins; D018077:Receptors, Leukotriene; D012243:Rhodopsin; C412375:cysteinyl leukotriene receptor 2; C083169:leukotriene D4 receptor