[Exercise-induced anaphylaxis after apple intake].
Exercise-induced anaphylaxis frequently is related to food ingestion, so that it receives the name of "food-dependent exercise-induced anaphylaxis". The food identification is difficult in some patients. We report two patients with apple-dependent exercise-induced anaphylaxis.


METHODS
hematimetries, biochemistries, VMA and 5-HIAA in urine. Complement levels, antinuclear antibodies and viruses serology.
skin prick test with a common inhalant. Skin prick test and prick by prick with different foods. Total Ig E level and specific Ig E determination by the CAP-Pharmacia System. Oral challenge test with apple, exercise test and exercise challenge test after eating an apple. Prick by prick test with fresh apple was positive. Specific Ig E determination by the CAP-Pharmacia System revealed a positive result. We get to reproduce the episode with an exercise challenge test after eating an apple in the same conditions of usual exercise in both patients.
Sánchez-Morillas
L
L
Clínica Universitaria Puerta de Hierro de Madrid. España. lsanchezmorillas@hotmail.com
Iglesias Cadarso
A
A
Zapatero Remón
L
L
Reaño Martos
M
M
Rodríguez Mosquera
M
M
Martínez Molero
M I
MI
D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000209:etiology*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D027845:Malus / Q000009:adverse effects*; D005082:Physical Exertion; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications; D012882:Skin Tests; D013177:Sports
D007073:Immunoglobulin E