Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child.
OBJECTIVE
To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population.


METHODS
Interventional case report.


METHODS
A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years.


RESULTS
Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition. She was treated with corticosteroids, aspirin, and gammaglobulin. This diminished the frequency and intensity of her attacks.


CONCLUSIONS
This case represents the diagnosis and treatment of AON in a child.
Frohman
Larry
L
Department of Ophthalmology, University of Medicine and Dentistry New Jersey, New Jersey Medical School, Newark, New Jersey, USA. frohman@umdnj.edu
Turbin
Roger
R
Bielory
Leonard
L
Wolansky
Leo
L
Lambert
W Clark
WC
Cook
Stuart
S
D017153:Antibodies, Anticardiolipin / Q000032:analysis*; D001241:Aspirin / Q000627:therapeutic use; D020274:Autoimmune Diseases of the Nervous System / Q000175:diagnosis* / Q000188:drug therapy; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy; D009902:Optic Neuritis / Q000175:diagnosis* / Q000188:drug therapy; D012867:Skin / Q000473:pathology
D017153:Antibodies, Anticardiolipin; D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D001241:Aspirin