title: [Current status of reduced-intensity stem cell transplantation; survey in the Kinki area].
abstract: The status of reduced-intensity stem cell transplantation (RIST) in the Kinki area was investigated by questionnaires. We sent out questionnaires to 72 institutions and received 51 replies (72.2%). RIST was performed in 16 institutions (31.4%). A total of 91 cases were included of whom approximately 70% were non-remission or advanced hematological malignancies. Various conditioning regimens were used for RIST, most often consisting of fludarabine, busulfan and antithymocte globulin. Acute GVHD developed in 57% of all patients. Relapse or disease progression developed in 42.7% of evaluable patients. The overall survival rate was 54.6%, and 80% of low risk patients were alive at the time of analysis.
authors.affiliation: Division of Hematology, Nephrology and Rheumatology, Department of Internal Medicine, Kinki University School of Medicine.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ashida
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Maeda
authors.forename: Akihisa
authors.initials: A
authors.lastname: Kanamaru
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Ichinohe
authors.forename: Takahisa
authors.initials: T
authors.lastname: Yamane
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hatanaka
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Ogawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hara
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Inoue
authors.forename: Tateo
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nagai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006086:Graft vs Host Disease / Q000517:prevention & control; D019337:Hematologic Neoplasms / Q000628:therapy; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D033581:Stem Cell Transplantation / Q000379:methods* / Q000401:mortality / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D015996:Survival Rate; D019172:Transplantation Conditioning / Q000009:adverse effects / Q000379:methods*