title: Comparison of clinical benefits of clopidogrel therapy in patients with acute coronary syndromes taking atorvastatin versus other statin therapies.
abstract: In clinical practice, we found no significant difference between atorvastatin therapy or other statin therapies in the clinical outcomes of patients with acute coronary syndromes receiving clopidogrel therapy. In patients receiving atorvastatin therapy, clopidogrel therapy was associated with a significant decrease in mortality and stroke during univariate analysis and a moderate trend of reduced mortality and stroke without statistical significance in the multivariate analysis.
authors.affiliation: Herzzentrum Ludwigshafen, Ludwigshafen, Germany. HarmWnbrgn@aol.com
authors.forename: Harm
authors.initials: H
authors.lastname: Wienbergen
authors.forename: Anselm Kai
authors.initials: AK
authors.lastname: Gitt
authors.forename: Rudolf
authors.initials: R
authors.lastname: Schiele
authors.forename: Claus
authors.initials: C
authors.lastname: Juenger
authors.forename: Tobias
authors.initials: T
authors.lastname: Heer
authors.forename: Christina
authors.initials: C
authors.lastname: Meisenzahl
authors.forename: Peter
authors.initials: P
authors.lastname: Limbourg
authors.forename: Claus
authors.initials: C
authors.lastname: Bossaller
authors.forename: Jochen
authors.initials: J
authors.lastname: Senges
mesh_terms: D000208:Acute Disease; D000368:Aged; D000069059:Atorvastatin; D000077144:Clopidogrel; D015897:Comorbidity; D003327:Coronary Disease / Q000188:drug therapy* / Q000401:mortality; D004347:Drug Interactions; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D005858:Germany / Q000453:epidemiology; D006538:Heptanoic Acids / Q000627:therapeutic use*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011758:Pyrroles / Q000627:therapeutic use*; D012042:Registries / Q000706:statistics & numerical data; D020521:Stroke / Q000453:epidemiology; D016019:Survival Analysis; D013577:Syndrome; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011758:Pyrroles; D000069059:Atorvastatin; D000077144:Clopidogrel; D013988:Ticlopidine