title: Defining monetary values for quality of life improvements: an exploratory study.
abstract: BACKGROUND
  QOL improvements, which can in many cases reflect the overall effect of a health intervention, are frequently measured. It would therefore be useful to define the monetary value of QOL improvements in order to subsequently estimate the value of a given intervention on the basis of its impact on QOL.
  
  
  OBJECTIVE
  To explore the feasibility of assessing the monetary value of an intervention by translating the improvement in QOL it produces into willingness to pay (WTP) amounts.
  
  
  METHODS
  Seven different hypothetical health state descriptions were developed. Five hundred and forty-five subjects randomly selected among the staff of the University of Montreal, Canada were sent a self-administered questionnaire asking them to evaluate the QOL corresponding to various hypothetical health states and indicate the amount they would be willing to pay for interventions that would enable them to move from these health states to perfect health.
  
  
  RESULTS
  The response rate was 55% (n = 294). A significant correlation was found between the WTP amount and the anticipated QOL improvement, and between the WTP amount and the respondent's family income. A regression equation for WTP amounts was derived from a step-wise model including the anticipated QOL improvement and the respondent income. While the model could only account for about 20% of the WTP variance (R(2) = 0.2), the mean predicted WTP amounts were very close to the mean WTP amounts observed in the sample.
  
  
  CONCLUSIONS
  This study indicates that a definite correlation exists between willingness to pay for an intervention and the improvement in QOL it produces.
authors.affiliation: Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada. jean.lachaine@umontreal.ca
authors.forename: Jean
authors.initials: J
authors.lastname: Lachaine
authors.forename: Claudine
authors.initials: C
authors.lastname: Laurier
authors.forename: André-Pierre
authors.initials: AP
authors.lastname: Contandriopoulos
mesh_terms: D000328:Adult; D001294:Attitude to Health; D002170:Canada; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D005260:Female; D005382:Financing, Personal / Q000191:economics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D016896:Treatment Outcome