Depression, mortality, and medical morbidity in patients with coronary heart disease.
There is substantial evidence that depression is a risk factor for cardiac morbidity and mortality, both for patients without clinical evidence of coronary heart disease at index examination and for patients with established coronary disease. The relationship is most apparent for patients with a recent acute myocardial infarction. Many questions about the impact of depression on heart disease remain unresolved.
Carney
Robert M
RM
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA.
Freedland
Kenneth E
KE
D015897:Comorbidity; D003327:Coronary Disease / Q000401:mortality*; D003863:Depression / Q000401:mortality; D003866:Depressive Disorder / Q000401:mortality* / Q000503:physiopathology; D006801:Humans; D009203:Myocardial Infarction / Q000401:mortality; D014481:United States / Q000453:epidemiology