title: Efficacy of the triple therapy: proton pomp inhibitors, amoxicillin and tynidazole in Helicobacter pylori infection treatment.
abstract: The aim of the paper is to present the triple therapy results combined with the application of proton pump inhibitors with amoxicillin and tynidazole in treatment of the contagion caused by Helicobacter pylori. The therapy was carried out among 108 people after realization of endoscopic biopsy and with quick urease test. In the endoscopic investigation 72 people were found to have duodenum ulceration. Inflammation of mucous duodenum was found in 36 patients. Among 108 people under investigation 51.85% were men and 48.15% women. These people were aged between 15-81 (the average age was 44). After the use of eradication 99 out of 108 patients (91.66%) were cured. The lack of improvement was found in 9 people (8.34%). The age of these people varied from 18 to 75, which gives the average age 54.5 (this age is about 10 years and a half higher in relation to the average age of the examined group of patients). The results prove high efficiency of this schema of treatment in relation to comparatively low costs. They also indicate greater efficiency of the treatment of contagious caused by Helicobacter pylori in younger people.
authors.affiliation: 2nd Department of General Surgery, Medical University of Lublin.
authors.forename: Marek
authors.initials: M
authors.lastname: Kos
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Zinkiewicz
authors.forename: Janusz
authors.initials: J
authors.lastname: Stefanek
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dabrowski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000008:administration & dosage*; D000897:Anti-Ulcer Agents / Q000008:administration & dosage*; D000994:Antitrichomonal Agents / Q000008:administration & dosage*; D001706:Biopsy; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000473:pathology; D004382:Duodenitis / Q000188:drug therapy* / Q000473:pathology; D004384:Duodenoscopy; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000473:pathology; D016480:Helicobacter pylori; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors; D014011:Tinidazole / Q000008:administration & dosage*
chemical_list: D000897:Anti-Ulcer Agents; D000994:Antitrichomonal Agents; D054328:Proton Pump Inhibitors; D014011:Tinidazole; D000658:Amoxicillin