title: Canine distemper, a re-emerging morbillivirus with complex neuropathogenic mechanisms.
abstract: Paramyxoviruses are responsible for a wide variety of diseases both in humans and in animals. Common to many paramyxoviruses is the fact that they can cause neurological symptoms in their final host. Newly discovered paramyxoviruses, such as the Hendra and Nipah viruses, show the same pattern of pathogenesis as that of the paramyxoviruses already known. Canine distemper virus (CDV) is a well-studied member of the genus Morbillivirus. Study of the neuropathogenesis of CDV might give insight into disease mechanisms and suggest approaches for the prevention of other recently discovered paramyxovirus infections.
authors.affiliation: Institute of Virology and Immunoprophylaxis, Swiss Federal Veterinary Office, 3147 Mittelhäusern, Switzerland. Christian.Griot@ivi.admin.ch
authors.forename: Christian
authors.initials: C
authors.lastname: Griot
authors.forename: Marc
authors.initials: M
authors.lastname: Vandevelde
authors.forename: Martina
authors.initials: M
authors.lastname: Schobesberger
authors.forename: Andreas
authors.initials: A
authors.lastname: Zurbriggen
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000473:pathology / Q000821:virology; D021821:Communicable Diseases, Emerging / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D003711:Demyelinating Diseases / Q000473:pathology / Q000662:veterinary / Q000821:virology; D004216:Distemper / Q000473:pathology / Q000821:virology; D004217:Distemper Virus, Canine / Q000472:pathogenicity; D004283:Dog Diseases / Q000473:pathology / Q000821:virology*; D004285:Dogs; D009186:Myelin Sheath / Q000473:pathology / Q000821:virology; D018184:Paramyxoviridae Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D018098:Paramyxovirinae / Q000472:pathogenicity*; D015047:Zoonoses