[Electronic mechanisms of molecular oxygen bioactivation].
Electronic mechanisms of reductive activation of O2 by oxidases coenzymes (K) are considered. Activation is induced by triplet-singlet (T-S)-transitions at the charge-transfer stage and K+...O2- radical pair (RP) formation. For flavoproteins the spin reversion is induced by spin-orbit coupling (SOC) in superoxide ion, for metal-oxidases--by exchange interaction with paramagnetic metal ion. Another type of spin activation is connected with the singlet peroxide ion O(2)2- formation in cytochromes (structures of the type Fe(3+)-O- -O-Cu2+).
Minaev
B F
BF
Engineering and Technology Institute, Cherkassy, Ukraine. leta@chiti.uch.net
D006631:Amine Oxidase (Copper-Containing) / Q000378:metabolism; D000818:Animals; D003580:Cytochromes / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D005949:Glucose Oxidase / Q000378:metabolism; D006422:Hemerythrin / Q000378:metabolism; D006433:Hemocyanins / Q000378:metabolism; D006801:Humans; D008084:Lipoxygenase / Q000378:metabolism; D008968:Molecular Conformation; D015394:Molecular Structure; D010100:Oxygen / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism
D003580:Cytochromes; D006422:Hemerythrin; D013481:Superoxides; D006433:Hemocyanins; D005949:Glucose Oxidase; D008084:Lipoxygenase; D006631:Amine Oxidase (Copper-Containing); D010100:Oxygen