title: Cytotoxicity of denture base acrylic resins: a literature review.
abstract: Acrylic resins are widely used in the fabrication of denture bases and have been shown to be cytotoxic as a result of substances that leach from the resin. The primary eluate is residual monomer. Numerous reports suggest that residual monomer may be responsible for mucosal irritation and sensitization of tissues. This information is important, not only to assess the biologic effects of such materials, but also to enable a comparison among the different polymerization methods, thus assisting the clinician in selecting a material with minimal cytotoxicity. This article reviews the literature published from 1973 to 2000, selected by use of a Medline search, associated with cytotoxic effects usually ascribed to acrylic denture base materials.
authors.affiliation: Araraquara Dental School, São Paulo State University, Brazil.
authors.forename: Janaina Habib
authors.initials: JH
authors.lastname: Jorge
authors.forename: Eunice Teresinha
authors.initials: ET
authors.lastname: Giampaolo
authors.forename: Ana Lúcia
authors.initials: AL
authors.lastname: Machado
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Vergani
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry / Q000633:toxicity*; D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity; D003764:Dental Materials / Q000737:chemistry / Q000633:toxicity*; D003819:Denture Bases; D006801:Humans; D011108:Polymers
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials; D003764:Dental Materials; D011108:Polymers