[Multiple human cord blood transfusion for inducing low immune response].
OBJECTIVE
To investigate and evaluate a clinically perspective way of inducing transplantation tolerance.


METHODS
Multi-cord blood transfusion was performed before kidney transplantation in 20 cases. Donor-specific mixed lymphocyte reaction(MLR) and allograft rejection were observed and studied.


RESULTS
The donor-specific MLR was suppressed in every recipient. No allograft rejection took place in the cord blood transfusion group three months after kidney transplantation.


CONCLUSIONS
Multi-cord blood transfusion is a practical way of inducing transplantation tolerance.
Zhao
Luping
L
Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Wang
Chengxiao
C
Wang
Li
L
Li
Hong
H
Yang
Yuru
Y
Lu
Yiping
Y
D000328:Adult; D001803:Blood Transfusion / Q000379:methods; D005260:Female; D005312:Fetal Blood / Q000637:transplantation*; D006086:Graft vs Host Disease / Q000517:prevention & control*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D016030:Kidney Transplantation / Q000276:immunology*; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D008875:Middle Aged; D014511:Uremia / Q000601:surgery