title: An efficient one-pot approach to bridged bicyclic ring-systems through consecutive hetero-domino transformations: a mechanistic rationale and further rearrangements.
abstract: This article describes the design of olefin-generated/reagent-modulated consecutive hetero-domino reactions of 1,2-unsaturated bicyclic diols, which are potentially of great use, initiated by PhI(OAc)(2), continued by [Pb(OAc)(4)], and completed by use of a mild base (K(2)CO(3)). Inversion of a quaternary center has been achieved through a three-reaction sequence: a domino transformation followed by an m-CPBA-mediated Baeyer-Villiger oxidation and subsequent reductive lactone ring opening.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS Avenue de la Terrasse 91198 Gif-sur Yvette, France.
authors.forename: Laure
authors.initials: L
authors.lastname: Finet
authors.forename: José I
authors.initials: JI
authors.lastname: Candela Lena
authors.forename: Talbi
authors.initials: T
authors.lastname: Kaoudi
authors.forename: Nicolas
authors.initials: N
authors.lastname: Birlirakis
authors.forename: Siméon
authors.initials: S
authors.lastname: Arseniyadis