Changes of nailfold microcirculation in patients of type II diabetes mellitus with diabetic retinopathy.
OBJECTIVE
To study the changes of microcirculation in patients with diabetic retinopathy (DR).


METHODS
Examination were performed in 153 cases of type I diabetes mellitus, among them, 72 cases were male, 81 cases were female, mean age 57.0+/-10.0 years, mean disease course 8.2+/-7.5 years. All cases were examined fundi by ophthalmologist, urinary albumin excretion rate (UAE) in 24 hours was measured by radioimmunoassay. Moreover, we examined the blood glucose, blood pressure, blood viscosity and observed the changes of naifold microcirculation.


RESULTS
It was found that there were more evident disturbance of microcirculation, markedly slowed velocity of blood flow (P<0.05), significantly increased aggregation of blood cells (P<0.05) and exudation around the loop (P<0.05) in the group with DR, compared with the group without DR.


CONCLUSIONS
It was more evident disturbance of nailfold microcirculation in patients with diabetic retinopathy.
Yi
Y
Y
Department of Microcirculation and Diabetes, Beijing Tong Ren Hospital, Beijing 100730.
Baoyu
W
W
Shenyuan
Y
Y
Liangxiang
Z
Z
Hanqing
F
F
Yuantao
L
L
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology*; D003930:Diabetic Retinopathy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D009262:Nails / Q000098:blood supply*