Cutaneous findings in a 51-year-old man with phenylketonuria.
A man with phenylketonuria who was reported to have lichen sclerosus et atrophicus at age 16 years presented to our institution 35 years later with large confluent areas of atrophy. Although sclerodermatous changes have been described in children with phenylketonuria, this case offers a longitudinal view of the progression of skin lesions in a middle-aged man with phenylketonuria.
Belloso
Leslie M
LM
Department of Internal Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Lowitt
Mark H
MH
D001707:Biopsy, Needle; D004035:Diet Therapy; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D018459:Lichen Sclerosus et Atrophicus / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010661:Phenylketonurias / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D018570:Risk Assessment; D012720:Severity of Illness Index