title: Cell-compatible properties of calcium carbonates and hydroxyapatite deposited on ultrathin poly(vinyl alcohol)-coated polyethylene films.
abstract: Poly(vinyl alcohol) (PVA) was coated onto polyethylene (PE) films by a repetitive adsorption and drying process, and then the PVA-coated PE films were alternately immersed into aqueous solutions of Ca2+ and CO3(2-) ions (alternate soaking cycles), to deposit calcium carbonate (CaCO3) onto the films. The PVA coating was essential for the CaCO3 deposition. The amount of CaCO3 deposited increased with an increasing number of cycles. Scanning electron microscopic observations and attenuated total reflection spectra revealed the presence of both calcite and aragonite as the crystal structures of CaCO3 on the film. L929 fibroblast cells adhered and proliferated on these CaCO3-deposited PE films, as well as the hydroxyapatite-coated PE films previously prepared. It was found that the PVA coating and the subsequent deposition of calcium salts on certain films facilitated cell compatibility.
authors.affiliation: Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-2140 Korimoto, Kagoshima 890-0065, Japan. tserizaw@apc.kagoshima-u.ac.jp
authors.forename: Takeshi
authors.initials: T
authors.lastname: Serizawa
authors.forename: Taishi
authors.initials: T
authors.lastname: Tateishi
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Akashi
mesh_terms: D002119:Calcium Carbonate / Q000737:chemistry* / Q000494:pharmacology; D002448:Cell Adhesion; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000494:pharmacology; D017886:Durapatite / Q000737:chemistry* / Q000494:pharmacology; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D020959:Polyethylene; D011142:Polyvinyl Alcohol; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible; D020959:Polyethylene; D011142:Polyvinyl Alcohol; D017886:Durapatite; D002119:Calcium Carbonate