A triterpene ozonide from Senecio selloi.
From the dried and fresh aerial parts of Senecio selloi Spreng, De Candolle (Asteraceae), the new triterpene ozonide 1 was isolated. Its structure was elucidated by NMR experiments, including inverse techniques HMQC and HMBC and by synthesis from the precursor 2 In contrast to natural peroxides, no antiplasmodial activity was detected for the ozonide 1.
Rücker
Gerhard
G
Pharmazeutisches Institut der Universität Bonn, Kreuzbergweg 26, D-53115 Bonn, Germany. pharmchem@uni-bonn.de
Manns
Detlef
D
Schenkel
Eloir P
EP
Hartmann
Rudolf
R
Heinzmann
Berta M
BM
D000962:Antimalarials / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010126:Ozone / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D012674:Senecio / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification*
D000962:Antimalarials; D010936:Plant Extracts; D014315:Triterpenes; D010126:Ozone