title: Supercritical fluid extraction of naringin from the peel of Citrus paradisi.
abstract: The highest yield (14.4 g/kg) of naringin, the major flavonoid from the peel of Citrus paradisi L., that could be achieved by supercritical fluid extraction was obtained using supercritical carbon dioxide modified with 15% ethanol and fresh (rather than dried) peels at 95 bar and 58.6 degrees C. This yield is higher than that attained by the conventional technique of maceration, and close to those obtained by reflux and Soxhlet methods. Furthermore, supercritical fluid extraction consumes less solvent and provides a shorter extraction time than conventional extraction methods.
authors.affiliation: Instituto de Ciencias Químicas, Facultad de Agronomía y Agroindustrias, Universidad Nacional de Santiago del Estero, Av. Belgrano (S) 1912 (4200), Santiago del Estero, Argentina.
authors.forename: Amelia N
authors.initials: AN
authors.lastname: Giannuzzo
authors.forename: Héctor J
authors.initials: HJ
authors.lastname: Boggetti
authors.forename: Mónica A
authors.initials: MA
authors.lastname: Nazareno
authors.forename: Horacio T
authors.initials: HT
authors.lastname: Mishima
mesh_terms: D025924:Chromatography, Supercritical Fluid; D032083:Citrus paradisi / Q000737:chemistry*; D044950:Flavanones; D005419:Flavonoids / Q000032:analysis / Q000302:isolation & purification*; D015394:Molecular Structure; D019441:Plant Epidermis / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D044950:Flavanones; D005419:Flavonoids; D010936:Plant Extracts; C005274:naringin