title: Long-term follow-up of patients after gamma intracoronary brachytherapy failure (from GAMMA-I, GAMMA-II, and SCRIPPS-III).
abstract: We report the long-term outcome of 225 patients who failed gamma-brachytherapy for in-stent restenosis. Total adverse events, target vessel revascularization, and myocardial infarction were higher after repeat percutaneous coronary intervention versus coronary artery bypass grafting. Therefore, coronary artery bypass grafting may be the preferable first-line therapy in these patients until other therapies (i.e., drug-eluting stents) are available. Shorter time from brachytherapy to radiation failure and late thrombosis after brachytherapy were independent predictors of adverse events.
authors.affiliation: Cardiovascular Research Foundation, New York, New York 10022, USA.
authors.forename: Thosaphol
authors.initials: T
authors.lastname: Limpijankit
authors.forename: Roxana
authors.initials: R
authors.lastname: Mehran
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: George
authors.initials: G
authors.lastname: Dangas
authors.forename: Alexandra J
authors.initials: AJ
authors.lastname: Lansky
authors.forename: John
authors.initials: J
authors.lastname: Kao
authors.forename: Dale T
authors.initials: DT
authors.lastname: Ashby
authors.forename: Issam
authors.initials: I
authors.lastname: Moussa
authors.forename: Gregg W
authors.initials: GW
authors.lastname: Stone
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Moses
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
authors.forename: Paul S
authors.initials: PS
authors.lastname: Teirstein
mesh_terms: D001918:Brachytherapy / Q000379:methods / Q000706:statistics & numerical data*; D023903:Coronary Restenosis / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D009204:Myocardial Revascularization / Q000706:statistics & numerical data; D012086:Reoperation / Q000706:statistics & numerical data; D016019:Survival Analysis; D013995:Time; D017211:Treatment Failure; D014481:United States / Q000453:epidemiology