title: IMP-GMP 5'-nucleotidase in reptiles: occurrence in a turtle, a tortoise and three species of snakes.
abstract: IMP-hydrolyzing activity, which is reactive with goose anti-pig lung IMP-GMP 5'-nucleotidase (c-N-II: EC.3.1.3.5) serum, was detected in extracts from liver, heart, kidney, spleen, stomach, skeletal muscle and lung from several species of reptiles: The values found in liver (U/mg protein) of one animal were: 4.5 for an ammono-ureotelic turtle (Trionyx sinensis japonicus); 3.7 for an ureo-uricotelic tortoise (Testudo elegans); 13-23 for three species of uricotelic snakes: Elaphe quadrivirgata, Elaphe conspicillata and Elaphe climacophora. These findings suggest that in the liver of snakes, c-N-II may participate in the production of uric acid as an end product of amino acid metabolism.
authors.affiliation: Department of Home Economics, Tokyo Kasei Gakuin University, 2600 Aiharamachi, Machida-city, Tokyo 194-0292, Japan. roytoh@kasei-gakuin.ac.jp
authors.forename: Roichi
authors.initials: R
authors.lastname: Itoh
authors.forename: Kayoko
authors.initials: K
authors.lastname: Kimura
mesh_terms: D015720:5'-Nucleotidase / Q000378:metabolism*; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D006157:Guanosine Monophosphate / Q000378:metabolism*; D012911:Snakes / Q000378:metabolism*; D013379:Substrate Specificity; D014018:Tissue Distribution; D014426:Turtles / Q000378:metabolism*; D014527:Uric Acid / Q000378:metabolism*
chemical_list: D014527:Uric Acid; D000641:Ammonia; D006157:Guanosine Monophosphate; D015720:5'-Nucleotidase