title: Metastatic testicular rhabdomyosarcoma--a report of two cases.
abstract: Rhabdomyosarcoma is the most common type of soft tissue sarcoma in children. The tumor spreads by local extension, to regional lymph nodes, or by distant metastases. Metastatic spread to the testicle has been rarely described. The authors describe 2 boys who were found to have intratesticular metastases after presenting with primary tumors in their extremities. The first patient, an 11-year-old boy presented with primary disease in his left foot and an enlarged testicle. Rhabdomyosarcoma was found histologically in both the foot and the testicle. A second boy 17 years of age had a primary tumor involving the left upper extremity treated with amputation, chemotherapy, and radiotherapy. A relapse was noted 2 years later in the left testicle and was treated with orchiectomy. The authors discuss the implications and the management of this rare presentation of metastatic rhabdomyosarcoma.
authors.affiliation: Department of Surgery, BC Children's and Women's Health Centre and University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Gow
authors.forename: James J
authors.initials: JJ
authors.lastname: Murphy
authors.forename: John K
authors.initials: JK
authors.lastname: Wu
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Desa
mesh_terms: D000293:Adolescent; D002648:Child; D017809:Fatal Outcome; D005534:Foot Diseases / Q000473:pathology; D006225:Hand; D006801:Humans; D008297:Male; D012208:Rhabdomyosarcoma / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D013736:Testicular Neoplasms / Q000556:secondary*