Ground-glass computed tomography pattern in chronic beryllium disease: pathologic substratum and evolution.
Five cases of chronic beryllium disease with predominant or isolated diffuse ground-glass lung opacities on computed tomography are reported with correlation to lung pathology. The ground-glass attenuation was either homogeneous and isolated (n = 1) or patchy and clearly predominant (n = 4) over linear and nodular opacities. In 4 cases, histologic samples showed a prominent diffuse involvement of the alveolar-capillary walls by florid granulomas. Evolution under corticosteroid was remarkable by the appearance of small-sized cysts in 3 cases.
Naccache
Jean-Marc
JM
Services de Pneumologie, Assistance Publique-Hôpitaux de Paris, Hôpital Avicenne, 125 rue de Stalingrad, 93009 Bobigny, France. jean-marc.naccache@wanadoo.fr
Marchand-Adam
Sylvain
S
Kambouchner
Marianne
M
Guillon
François
F
Monnet
Isabelle
I
Girard
Frederic
F
Brauner
Michel
M
Valeyre
Dominique
D
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001607:Berylliosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones