title: Malaria parasite and vector genomes: partners in crime.
abstract: The publication of the genome sequences of the malaria parasite Plasmodium falciparum and the insect vector Anopheles gambiae paves the way for scientists to study these organisms by using technologies developed to observe global changes in transcription and translation, as well as computational tools. Researchers are now able to investigate complex changes involved in development, growth and reaction to external factors. Given the medical importance of these organisms, much of this work is targeted on drug or insecticide discovery (including mechanisms of resistance to existing treatments), but the genome information also provides the opportunity to develop novel therapies.
authors.affiliation: Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK. agcraig@liv.ac.uk
authors.forename: Alister
authors.initials: A
authors.lastname: Craig
authors.forename: Susan
authors.initials: S
authors.lastname: Kyes
authors.forename: Hilary
authors.initials: H
authors.lastname: Ranson
authors.forename: Janet
authors.initials: J
authors.lastname: Hemingway
mesh_terms: D000818:Animals; D000852:Anopheles / Q000235:genetics*; D016678:Genome; D018503:Genome, Protozoan; D006801:Humans; D007303:Insect Vectors / Q000235:genetics*; D008957:Models, Genetic; D010963:Plasmodium falciparum / Q000235:genetics*