The effect of deprivation and the systemic inflammatory response on outcome following curative resection for colorectal cancer.
The presence of a systemic inflammatory response predicted cancer-specific (HR 2.55, 95% CI 1.22-5.32, P<0.05) and overall survival (HR 2.12, 95% CI 1.17-3.87, P<0.05), independent of Dukes stage, in patients who had undergone apparently curative surgery for colorectal cancer (n=158). Deprivation predicted overall survival (HR 1.26, 95% CI 1.04-1.51, P<0.05) independent of Dukes stage.
McMillan
D C
DC
University Department of Surgery, Royal Infirmary, Glasgow G31 ZER, UK. d.c.mcmillan@clinmed.gla.ac.uk
Canna
K
K
McArdle
C S
CS
D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis; D015179:Colorectal Neoplasms / Q000097:blood / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011203:Poverty; D011379:Prognosis; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome
D002097:C-Reactive Protein