[Surgical intervention of hepatocellular carcinoma with bile duct thrombi].
OBJECTIVE
To summarize the experience of surgical intervention for hepatocellular carcinoma (HCC) with bile duct thrombi (BDT), and to evaluate the influence on prognosis.


METHODS
From 1994 to 2002, 15 patients with HCC and BDT who underwent surgical intervention were retrospectively analyzed.


RESULTS
The operative procedures included hepatectomy with removal of BDT (n = 7), hepatectomy combined with extrahepatic bile duct resection (n = 4), thrombectomy through choledochotomy (n = 3), and piggy-back orthotopic liver transplantation (n = 1). The 1- and 3-year survival rates were 73.3% and 40%, respectively. Two patients survived over 5 year. The survival rate of patients with portal vein invasion was significantly lower than that of patients without portal vein invasion (P < 0.05).


CONCLUSIONS
Surgical intervention was effective for patients with HCC and BDT. Operation after recurrence can prolong the survival time. Liver transplantation is a new operative procedure worthy of study.
Peng
Shu-you
SY
Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009 China.
Wang
Jian-wei
JW
Liu
Ying-bin
YB
Cai
Xiu-jun
XJ
Mou
Yi-ping
YP
Wu
Yu-lian
YL
Fang
He-qing
HQ
Peng
Cheng-hong
CH
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000601:surgery*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013927:Thrombosis / Q000601:surgery*