[Blastocystosis: nitazoxanide as a new therapeutic option].
We report a case of a patient with AIDS and severe immunosuppression who developed diarrhea due to a vacuolar stage of Blastocystis hominis. The patient was treated with nitazoxanide, a 5-nitrothiazole broad-spectrum antiparasitic agent. We obtained complete remission of symptoms and eradication of the parasite. Nitazoxanide is a new treatment option for blastocystosis in AIDS patients. Further studies to test its efficacy are needed.
Cimerman
Sérgio
S
3ra. Unidade de Internação, Instituto de Infectologia Emílio Ribas, São Paulo, SP, Brasil. scimerman@uol.com.br
Ladeira
Maria Cecília Teixeira
MC
Iuliano
Wilma Assunção
WA
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy*; D000328:Adult; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D016776:Blastocystis Infections / Q000175:diagnosis / Q000188:drug therapy*; D016845:Blastocystis hominis / Q000302:isolation & purification*; D005243:Feces / Q000469:parasitology; D006801:Humans; D008297:Male; D009574:Nitro Compounds; D010270:Parasite Egg Count; D013844:Thiazoles / Q000627:therapeutic use*
D000981:Antiprotozoal Agents; D009574:Nitro Compounds; D013844:Thiazoles; C041747:nitazoxanide