Controversies in clinical pancreatology: should the sphincter of Oddi be measured in patients with idiopathic recurrent acute pancreatitis, and should sphincterotomy be performed if the pressure is high?
The risk benefit ratio of measuring the sphincter of Oddi pressure and performing sphincterotomy in patients with idiopathic acute pancreatitis with high sphincter pressures has not been assessed. Few healthy controls have had sphincter measurements so that the definition of an abnormal sphincter remains understudied. The procedures involved have significant risks and the benefits are hard to measure considering the variable natural history of this disorder. No prospective, randomized investigations have been performed to evaluate efficacy of these invasive procedures. It is the author's opinion that until appropriate studies prove efficacy that these interventions be considered experimental.
Steinberg
William M
WM
D000208:Acute Disease; D005500:Follow-Up Studies; D006801:Humans; D008365:Manometry / Q000379:methods; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D012307:Risk Factors; D055502:Secondary Prevention; D009803:Sphincter of Oddi / Q000503:physiopathology* / Q000601:surgery; D016717:Sphincterotomy, Endoscopic