title: Human chromosome 16 conservation in primates.
abstract: A study was made of the organization of the chromosome orthologous to HSA16 in primates using a panel of 8 BAC probes spanning human chromosome 16. The probes were used in FISH experiments on great apes and on representatives of the Old World monkeys, New World monkeys, and lemurs. The domestic cat was used as an outgroup. The results indicate that 16p and 16q were separate chromosomes in a primate ancestor. They fused in a Catarrhini ancestor giving rise to the present day form found in HSA, great apes, and Old World monkeys. Several rearrangements were found in New World monkeys.
authors.affiliation: Sezione di Genetica, DAPEG, Via Amendola 165/A 70126 Bari, Italy.
authors.forename: Doriana
authors.initials: D
authors.lastname: Misceo
authors.forename: Mario
authors.initials: M
authors.lastname: Ventura
authors.forename: Verena
authors.initials: V
authors.lastname: Eder
authors.forename: Mariano
authors.initials: M
authors.lastname: Rocchi
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Archidiacono
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D020223:Chromosome Painting; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D015342:DNA Probes; D030541:Databases, Genetic; D019143:Evolution, Molecular; D006801:Humans; D011323:Primates / Q000235:genetics*
chemical_list: D015342:DNA Probes