title: [Phytoestrogen and cancer prevention].
abstract: Phytoestrogens are defined to be plant chemicals that modify estrogenic effects in the body by binding to the estrogen receptors in mammals. Isoflavones, coumestane, lignan, and prenylflavones are examples of these, with isoflavones from soy foods and lignans from rye being a major dietary contribution. Mechanisms of cancer prevention by these phytoestrogens are reviewed, and human epidemiological studies, especially for breast and prostate cancers, are summarized and the results discussed.
authors.affiliation: Department of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuraoka, Setagaya-ku, Tokyo 156-8502, Japan.
authors.forename: Shaw
authors.initials: S
authors.lastname: Watanabe
authors.forename: Sayo
authors.initials: S
authors.lastname: Uesugi
authors.forename: XingGang
authors.initials: X
authors.lastname: Zhuo
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kimira
mesh_terms: D001943:Breast Neoplasms / Q000517:prevention & control*; D004032:Diet; D004968:Estrogens, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007529:Isoflavones / Q000302:isolation & purification / Q000494:pharmacology; D017705:Lignans / Q000302:isolation & purification / Q000494:pharmacology; D008297:Male; D048789:Phytoestrogens; D028321:Plant Preparations; D011471:Prostatic Neoplasms / Q000517:prevention & control*; D012306:Risk; D030262:Soybean Proteins / Q000737:chemistry
chemical_list: D004968:Estrogens, Non-Steroidal; D007529:Isoflavones; D017705:Lignans; D048789:Phytoestrogens; D028321:Plant Preparations; D030262:Soybean Proteins