title: [Patients under 45 years of age "young adults" with head and neck squamous cell carcinoma. Retrospective, multivariable analysis--preliminary report ].
abstract: There is a clear tendency to diagnose squamous cell carcinoma of the head and neck more frequently in patients below 45 years of age. These neoplasms in "young adults" seem to be more aggressive with rapid progression, frequent reappearance after treatment and worse prognosis than is observed in older patient population. This preliminary report presents results of retrospective, multivariable analysis of patients below 45 years of age with squamous cell carcinoma of the head and neck. The special focus of the study were: disease progression (T), regional node and distant metastases (N,M), tobacco and alcohol consumption, environmental factors, concomitant diseases, kind of surgical technique and tumour histology.
authors.affiliation: Katedra i Klinika Otolaryngologii AM im. K. Marcinkowskiego w Poznaniu.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Golusinski
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Waśniewska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kaczmarek
authors.forename: Dawid
authors.initials: D
authors.lastname: Kedzia
authors.forename: Maciej
authors.initials: M
authors.lastname: Wróbel
authors.forename: Barbara
authors.initials: B
authors.lastname: Malinowska
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000428:Alcohol Drinking / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000503:physiopathology* / Q000556:secondary* / Q000601:surgery; D018450:Disease Progression; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D012959:Socioeconomic Factors; D013997:Time Factors