Neonatal pemphigus foliaceus.
The term "pemphigus" refers to a group of diseases that are characterized by the presence of cutaneous or mucosal blisters and erosions, and antiepidermal autoantibodies. There are several case reports of neonatal pemphigus vulgaris in the literature. Although pemphigus foliaceus antibodies have been shown to cross the placenta, to our knowledge, this is only the second reported case of neonatal pemphigus foliaceus. The proposed mechanism of disease transfer is the passive transfer of maternal IgG antibodies across the placenta.
Hirsch
Ranella
R
Department of Dermatology, State University of New York Health Science Center at Brooklyn, Brooklyn, NY, USA.
Anderson
Judy
J
Weinberg
Jeffrey M
JM
Burnstein
Penina
P
Echt
Audrey
A
Fermin
Janet
J
Heilman
Edward R
ER
Laude
Teresita A
TA
D000287:Administration, Topical; D001323:Autoantibodies / Q000276:immunology; D001707:Biopsy, Needle; D015820:Cadherins / Q000276:immunology*; D051183:Desmoglein 1; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D007150:Immunohistochemistry; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000276:immunology; D016712:Mupirocin / Q000008:administration & dosage; D010392:Pemphigus / Q000151:congenital* / Q000276:immunology / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D016896:Treatment Outcome
D001323:Autoantibodies; D015820:Cadherins; D051183:Desmoglein 1; D016712:Mupirocin; D006854:Hydrocortisone