title: Update on cicatricial alopecia.
abstract: Cicatricial alopecia is an enigmatic group of hair disorders linked by the potential permanent loss of scalp hair follicles in involved areas. Progress in our understanding and treatment of these disorders has been stymied by the lack of clear diagnostic criteria for the current terms used to describe the various hair loss entities. Since all of these conditions evolve as the hair is destroyed or replaced, diagnosis is further made difficult by a lack of clinical and pathologic "snapshots" over the evolution of each disorder. Without some acceptance of general clinical and histological presentations in the early, mid and late stage of these disorders, one cannot begin to explore ways to make the diagnosis at a very early stage before significant follicular destraction has occurred (making the clinical diagnosis obvious) and when the damage is potentially repairable or progression preventable.
authors.affiliation: Duke University Medical Center, Durham, NC 27710, USA. olsen001@mc.duke.edu
authors.forename: E
authors.initials: E
authors.lastname: Olsen
authors.forename: K
authors.initials: K
authors.lastname: Stenn
authors.forename: W
authors.initials: W
authors.lastname: Bergfeld
authors.forename: G
authors.initials: G
authors.lastname: Cotsarelis
authors.forename: V
authors.initials: V
authors.lastname: Price
authors.forename: J
authors.initials: J
authors.lastname: Shapiro
authors.forename: R
authors.initials: R
authors.lastname: Sinclair
authors.forename: A
authors.initials: A
authors.lastname: Solomon
authors.forename: L
authors.initials: L
authors.lastname: Sperling
authors.forename: D
authors.initials: D
authors.lastname: Whiting
mesh_terms: D000505:Alopecia / Q000145:classification / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D000818:Animals; D002921:Cicatrix / Q000150:complications*; D006801:Humans