title: Resolution of chronic inflammatory demyelinating polyneuropathy-associated central nervous system lesions after treatment with intravenous immunoglobulin.
abstract: Chronic inflammatory demyelinating polyneuropathy (CIDP) is a condition affecting the peripheral nervous system; however, it has been associated with central nervous system (CNS) involvement. The natural history and response to treatment of these CNS lesions are unknown. We report the case of a patient with CIDP which met research criteria for definite CIDP and associated symptomatic CNS lesions. She had resolution of her CNS-based clinical and radiographic findings with intravenous immunoglobulin (IVIG) therapy. IVIG is a reasonable treatment option when symptomatic, CIDP-associated CNS lesions are present.
authors.affiliation: Department of Neurology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Madison, WI 53792, USA.
authors.forename: Dominic B
authors.initials: DB
authors.lastname: Fee
authors.forename: John O
authors.initials: JO
authors.lastname: Fleming
mesh_terms: D001931:Brain Mapping; D002493:Central Nervous System Diseases / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000293:injuries / Q000378:metabolism; D006801:Humans; D007116:Immunization, Passive / Q000009:adverse effects; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects* / Q000627:therapeutic use; D007276:Injections, Intraventricular / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000150:complications* / Q000473:pathology / Q000628:therapy; D013497:Sural Nerve / Q000033:anatomy & histology / Q000293:injuries
chemical_list: D016756:Immunoglobulins, Intravenous