title: [A clinical study on coincidence with hyperthyroidism and thyroid carcinoma].
abstract: OBJECTIVE
  A retrospective study has been carried out to evaluate the prevalence of coincidence with hyperthyroidism and thyroid carcinoma.
  
  
  METHODS
  394 patients underwent surgery for hyperthyroidism and 245 patients suffered from thyroid cancer were chosen for the study in our hospital from January 1983 to June 1998.
  
  
  RESULTS
  Thyroid cancer and hyperthyroidism coincided in 12 patients. The incidence of thyroid cancer was 3.0% (12/394) in hyperthyroidism, and the incidence of hyperthyroidism was 4.9% in thyroid cancer. There were 7 female and 5 male, with a diffuse goiter (n = 3), a diffuse goiter with a cold nodule (n = 3), multinodular goiter (n = 6). Among the 12 patients, 7 patients had an occult thyroid cancer with a diameter of 1 cm or less, most of them with papillary carcinoma, less frequently had metastases, 4 patients had thyroid cancer with a diameter of 3 cm or more, and 3 patients had metastases.
  
  
  CONCLUSIONS
  The prevalence of coincidence with thyroid cancer and hyperthyroidism is more than that of thyroid cancer in population. Diagnostics for exclusion of thyroid cancer is required carefully even in the presence of hyperthyroidism.
authors.affiliation: Department of Endocrinology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China. lianlanx@public.bta.net.cn
authors.forename: X
authors.initials: X
authors.lastname: Lian
authors.forename: Y
authors.initials: Y
authors.lastname: Bai
authors.forename: W
authors.initials: W
authors.lastname: Tang
authors.forename: W
authors.initials: W
authors.lastname: Dai
authors.forename: Z
authors.initials: Z
authors.lastname: Guo
mesh_terms: D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications*; D008297:Male; D009362:Neoplasm Metastasis; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology