title: Plantar wart treatment with combination imiquimod and salicylic acid pads.
abstract: Treatment of plantar warts is often difficult and may be painful, often employing destructive treatment modalities. We report the successful treatment of a patient with a large plantar wart using Imiquimod 5% cream under occlusion with a 40% salicylic acid pad. This combination treatment modality likely allows successful delivery of Imiquimod through the thick skin on the plantar surface. Once penetrated, an anti-viral state is created by upregulating specific cytokines to eradicate the human papilloma virus (HPV).
authors.affiliation: Department of Dermatology, University of Texas-Houston Medical School, 6431 Fannin, Suite 1.204, Houston, TX 77030, USA.
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Tucker
authors.forename: Asra
authors.initials: A
authors.lastname: Ali
authors.forename: Brian L
authors.initials: BL
authors.lastname: Ransdell
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000634:Aminoquinolines / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005528:Foot / Q000473:pathology* / Q000821:virology; D006801:Humans; D008297:Male; D020156:Salicylic Acid / Q000008:administration & dosage*; D014860:Warts / Q000188:drug therapy*
chemical_list: D000634:Aminoquinolines; D020156:Salicylic Acid