title: Accuracy and precision of the amadeus microkeratome in producing LASIK flaps.
abstract: OBJECTIVE
  To evaluate the accuracy and precision of corneal flap thickness following laser in situ keratomileusis (LASIK) performed using the 140-, 160-, and 180-microm heads for the Amadeus microkeratome (AMO, Irvine, CA).
  
  
  METHODS
  The study took place at the Cullen Eye Institute, Baylor College of Medicine, Houston.
  
  
  METHODS
  In this prospective study, using the Amadeus microkeratome, LASIK flaps were cut in 51 right eyes and 50 left eyes with the 140-microm head, 25 right eyes and 25 left eyes with the 160-microm head, and five right eyes and one left eye with the 180-microm head. The same microkeratome blade was used for bilateral cases with the right eyes always undergoing surgery first. Eyes were grouped by order of blade use for statistical analysis. The effect of preoperative corneal thickness, keratometry values, blade oscillation and translation speeds, and blade reuse on flap thickness was evaluated.
  
  
  RESULTS
  Mean flap thicknesses were 153 +/- 18 (range 97-187 microm) OD and 134 +/- 25 microm (range 79-174 microm) OS for the 140-microm head; 182 +/- 26 microm (range 105-220 microm) OD and 163 +/- 29 microm (range 105-216 microm) OS for the 160-microm head; and 235 +/- 24 microm (range 198-258 microm) for the 180-microm head. Flap thickness was significantly thicker for the first eyes cut (right eyes) and was positively correlated with increasing corneal thickness in both eyes. For the first eyes cut, flap thickness was also significantly thicker than the labeled thickness specified by the manufacturer.
  
  
  CONCLUSIONS
  With the Amadeus microkeratome, LASIK flap thickness correlated with central corneal thickness for the 140-microm head. Reuse of the microkeratome blades produced significantly thinner LASIK flaps on second eyes cut.
authors.affiliation: Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Jackson
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Koch
mesh_terms: D004867:Equipment Design; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000295:instrumentation*; D011446:Prospective Studies; D013524:Surgical Flaps