Effect of ascovertin on morphofunctional changes in the ovaries in monopolar coagulation.
A course of ascovertin therapy reduced manifestations of perifocal inflammation and atresia of growing follicles, corrected vascular disorders and changes in the tissue volume ratios outside the necrotic zone after monopolar coagulation of the ovaries in rats. The drug prevented the increase in blood viscosity, erythrocyte aggregation, and LPO activation in the early postoperation period.
Logvinov
S V
SV
Siberian State Medical University, Tomsk. s_logvinov@mail.ru
Plotnikov
M B
MB
Tikhonovskaya
O A
OA
Bukharina
I Yu
IY
Maslov
M Yu
MY
Petrova
M S
MS
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D001809:Blood Viscosity / Q000187:drug effects; D004338:Drug Combinations; D004903:Erythrocyte Aggregation / Q000187:drug effects; D004912:Erythrocytes / Q000737:chemistry; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D044948:Flavonols / Q000494:pharmacology / Q000627:therapeutic use*; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects; D006400:Hematocrit; D010049:Ovarian Diseases / Q000188:drug therapy*; D010053:Ovary / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology*; D011184:Postoperative Period; D011794:Quercetin / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats
D000975:Antioxidants; D004338:Drug Combinations; D044948:Flavonols; D011794:Quercetin; C003377:taxifolin; D001205:Ascorbic Acid