IL-5 expression in the sputum of patients with bronchial asthma.
Expression of IL-5 mRNA and the content of IL-5 in the sputum of patients with asthma of different severity were studied before and after treatment. The expression of IL-5 mRNA in mild asthma differed from that in severe and moderate asthma before and after treatment. The level of IL-5 before therapy was different in patients with mild and severe disease. In patients with severe asthma the level of IL-5 differed before and after treatment.
Sazonov
A E
AE
Siberian State Medical University, Tomsk.
Petrovskii
F I
FI
Ivanchuk
I I
II
Gereng
E A
EA
Ogorodova
L M
LM
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D001249:Asthma / Q000188:drug therapy / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D015848:Interleukin-5 / Q000235:genetics / Q000378:metabolism*; D010366:Peak Expiratory Flow Rate; D012333:RNA, Messenger / Q000032:analysis; D013183:Sputum / Q000737:chemistry*
D000305:Adrenal Cortex Hormones; D015848:Interleukin-5; D012333:RNA, Messenger