title: [Good practices for the study of hemoglobin].
abstract: Hemoglobinopathies have become a significant national health problem in France. The biologists have a pivotal role in the genetic diagnoses. Although sickle cell disease (SCD) is the most frequent abnormality found: not less than 200 new cases are observed each year at birth, many other globin gene variations are found in the various ethnic groups. Since 1995 a neonatal sickle cell screening program has been established for at risk newborns. This programme is supported by the "Association française de dépistage et prévention des handicaps de l'enfant" (AFDPHE). The characterization of hemoglobin genetic variations requires a comprehensive set of laboratory techniques for which we specify here main clinical and technical recommendations.
authors.affiliation: Hôpital Henri Mondor, Créteil. josiane.michau@hmn.ap-hop-paris.fr
authors.forename: J
authors.initials: J
authors.lastname: Bardakdjian-Michau
authors.forename: J-L
authors.initials: JL
authors.lastname: Dhondt
authors.forename: R
authors.initials: R
authors.lastname: Ducrocq
authors.forename: F
authors.initials: F
authors.lastname: Galactéros
authors.forename: A
authors.initials: A
authors.lastname: Guyard
authors.forename: F-X
authors.initials: FX
authors.lastname: Huchet
authors.forename: A
authors.initials: A
authors.lastname: Lahary
authors.forename: D
authors.initials: D
authors.lastname: Lena-Russo
authors.forename: P
authors.initials: P
authors.lastname: Maboudou
authors.forename: M-L
authors.initials: ML
authors.lastname: North
authors.forename: C
authors.initials: C
authors.lastname: Prehu
authors.forename: A-M
authors.initials: AM
authors.lastname: Soummer
authors.forename: M
authors.initials: M
authors.lastname: Verschelde
authors.forename: H
authors.initials: H
authors.lastname: Wajcman
mesh_terms: D001774:Blood Chemical Analysis / Q000379:methods / Q000592:standards; D001800:Blood Specimen Collection; D006453:Hemoglobinopathies / Q000097:blood; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans
chemical_list: D006454:Hemoglobins