title: Plasma D-lactate levels in diagnosis of appendicitis.
abstract: We investigated the possible use of D-lactate as a predictor in the diagnosis of appendicitis. C-reactive protein level (CRP) and leukocyte counts were also evaluated. Venous blood D-lactate, CRP, and leukocyte counts were measured preoperatively in 53 patients undergoing surgery for appendicitis, as well as in 20 healthy subjects. Levels of all three parameters in the surgical patients were significantly higher than in the control group (p <.05). Previous studies have shown that venous D-lactate is more specific to the intestine than CPR or leukocyte count. Based on our data, venous D-lactate, which had the lowest false-negative rate among these laboratory parameters, may be a useful diagnostic marker for appendicitis. None of these parameters were helpful in identifying the type of the appendicitis.
authors.affiliation: Department of Pediatric Surgery, Medical Faculty, Kirikkale University, Kirikkale, Turkey. fatmacaglayan@yahoo.com
authors.forename: Fatma
authors.initials: F
authors.lastname: Cağlayan
authors.forename: Murat
authors.initials: M
authors.lastname: Cakmak
authors.forename: Osman
authors.initials: O
authors.lastname: Cağlayan
authors.forename: Turgut
authors.initials: T
authors.lastname: Cavuşoglu
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001064:Appendicitis / Q000097:blood* / Q000175:diagnosis*; D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism; D002648:Child; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D007958:Leukocyte Count; D008875:Middle Aged; D011237:Predictive Value of Tests
chemical_list: D015415:Biomarkers; D019344:Lactic Acid; D002097:C-Reactive Protein