title: 11-Hydroxy-3,3-dimethyl-7,12-dioxo-3,4,6,6a,7,12,12a,12b-octahydrobenz[a]anthracen-1-yl acetate.
abstract: The Diels-Alder reaction between 5-hydroxy-1,4-naphthoquinone and 5,5-dimethyl-3-vinyl-1,2-cyclohexadienyl acetate by endo addition gives the title compound, C(22)H(22)O(5), in 68% yield. This racemic diastereoisomer has the opposite regiochemistry to ochromycinone analogues produced previously and may allow access to a new type of anticancer-active saquayamycin analogue.
authors.affiliation: Department of Chemistry, University of Adelaide, South Australia 5005, Australia.
authors.forename: Tomas
authors.initials: T
authors.lastname: Rozek
authors.forename: John H
authors.initials: JH
authors.lastname: Bowie
authors.forename: Brian W
authors.initials: BW
authors.lastname: Skelton
authors.forename: Allan H
authors.initials: AH
authors.lastname: White