[Caloric overload in critically ill patients treated with parenteral nutrition].
OBJECTIVE
To assess the degree of hypernutrition of critically-ill patients under treatment with parenteral nutrition (PN) in a multi-purpose intensive care unit (ICU).


METHODS
Patients under treatment with parenteral nutrition in a multi-purpose intensive care unit. Prospective study lasting four months.


METHODS
The amounts of the daily dose of glucose, lipids and nitrogen were calculated in PN, enteral nutrition (EN), dextrose solution (DS) and propofol. The daily dose of glucose and lipid administered intravenously (i.v.) was assessed with respect to the recommended value (4-5 mg/kg/min and 1.5 g/kg/day, respectively) and with respect to the dose prescribed in the PN regime The total daily calorie intake (i.v. plus EN) was assessed with respect to the recommended value (25-35 kcal/kg/day).


RESULTS
The study involved 30 patients totalling 488 days with PN. The total daily dose of i.v. lipids (PN plus propofol) exceeded the recommended value on 23.2% of the days with propofol (13 of 56) and on 3.7% of the days without propofol (16 of 432). The total daily dose of i.v. dextrose did not exceed any day the maximum metabolization threshold. On 28.2% of the days with EN and 39.6% of the days without EN, the total daily dose of i.v. dextrose exceeded the PN regimen. Similarly, on 41% of the days with propofol, the total daily dose of i.v. lipids exceeded the PN regimen. The total calorie intake (i.v. plus EN) exceeded the recommended value on 46.9% of the days with EN (51 of 109) and on 5% of the days without EN (19 of 379).


CONCLUSIONS
The glucose of dextrose solution and the propofol lipid are not routinely discounted from the PN regime. A trend towards hypernutrition of the critically-ill patient is shown, especially on days with simultaneous treatment with PN and EN.
Juvany Roig
R
R
Servicio de Farmacia, Ciutat Sanitària i Universitària de Bellvitge, Feixa Llarga, s/n. 08907 L'Hospitalet de Llobregat, Barcelona, España. rjuvany@csub.scs.es
Llop Talaverón
J
J
Herrero Meseguer
I
I
Jódar Masanés
R
R
D003422:Critical Care; D016638:Critical Illness / Q000628:therapy*; D002149:Energy Intake; D005260:Female; D005526:Food, Formulated; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D010288:Parenteral Nutrition / Q000009:adverse effects*