Microtubule dynamics: new surprises from an old MAP.
Dis1/XMAP215 family microtubule-binding proteins are essential for cell division in animals, plants and fungi, suggesting a conserved cell-division mechanism used by all eukaryotes. Two new studies, however, reveal that different family members can have very different effects on microtubule dynamics.
McNally
Frank
F
Section of Molecular and Cellular Biology, University of California at Davis, Davis, CA 95616, USA.
D000705:Anaphase / Q000235:genetics / Q000502:physiology*; D008869:Microtubule-Associated Proteins / Q000235:genetics* / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins; D029867:Xenopus Proteins
C486738:CKAP5 protein, Xenopus; D008869:Microtubule-Associated Proteins; C109414:STU2 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D029867:Xenopus Proteins