Relation between the degree of procedural anticoagulation and complications after coronary stent implantation.
The impact of the degree of anticoagulation in patients who underwent stent implantation without glycoprotein IIb/IIIa inhibitors was examined in 1,020 patients. High levels of procedural anticoagulation with heparin were found to increase hemorrhagic complications without improving clinical or angiographic outcomes.
Ashby
Dale T
DT
Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA.
Dangas
George
G
Aymong
Eve A
EA
Farkouh
Michael E
ME
Mehran
Roxana
R
Lansky
Alexandra J
AJ
Moses
Jeffery W
JW
Leon
Martin B
MB
Stone
Gregg W
GW
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D023921:Coronary Stenosis / Q000601:surgery*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017202:Myocardial Ischemia / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D019106:Postoperative Hemorrhage / Q000209:etiology; D015607:Stents; D014914:Whole Blood Coagulation Time
D000925:Anticoagulants; D006493:Heparin