title: The influence of zinc and copper supplementation in feed on the concentrations of certain metals in rats' skin.
abstract: Zinc and copper, administered to the organism in excess can also influence the concentrations of other elements, and have a secondary influence on the processes that these elements regulate. The purpose of this experiment was to determine the influence of zinc and copper dietary supplementation on the concentrations of magnesium, calcium, zinc and copper in the rat's skin. The results showed that zinc supplementation caused a decrease in calcium concentration as well as an increase in zinc concentration in the tested materials. The concentrations of magnesium and copper changed insignificantly. Copper supplementation caused a decrease in the concentration of magnesium, calcium and zinc but caused an increase in copper concentration. Changes in concentrations of the tested metals were dependent upon the concentrations of various metals added to the rat's diets.
authors.affiliation: Department of General Chemistry, Medical University of Lublin, Medical Centre Galenus, Gniezno.
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Pasternak
authors.forename: Ewa
authors.initials: E
authors.lastname: Bielak
authors.forename: Włodzimierz
authors.initials: W
authors.lastname: Bulikowski
authors.forename: Wiesław
authors.initials: W
authors.lastname: Lingas
mesh_terms: D000818:Animals; D003300:Copper / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008297:Male; D008670:Metals / Q000032:analysis*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000737:chemistry*; D015032:Zinc / Q000494:pharmacology*
chemical_list: D008670:Metals; D003300:Copper; D015032:Zinc