title: Invited commentary.
authors.affiliation: Division of Cardiovascular Surgery, Toronto General Hospital, EN 13-217, 200 Elizabeth Street, M5G 2C4, Toronto, Ontario, Canada
authors.forename: Michael A
authors.initials: MA
authors.lastname: Borger
authors.forename: Paul W M
authors.initials: PW
authors.lastname: Fedak
authors.forename: Richard D
authors.initials: RD
authors.lastname: Weisel
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods / Q000401:mortality*; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000401:mortality*; D012042:Registries; D018570:Risk Assessment; D016019:Survival Analysis; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology