title: Malignant B cell non-Hodgkin's lymphoma of the larynx in children with Wiskott Aldrich syndrome.
abstract: A 15 years old male with a primary diagnosis of Wiskott Aldrich syndrome presented a laryngeal B cell lymphoma associated with Epstein-Barr virus. A chemotherapy and a radiotherapy were started in association with an endoscopic debulking of the tumor. The child died of respiratory failure secondary to a lung infection. The incidence of NHL (non-Hodgkin's lymphoma) of laryngeal origin in infants is extremely low and to our knowledge it has never been found in Wiskott Aldrich syndrome.
authors.affiliation: Service d'oncologie pédiatrique, Hôpital Arnaud de Villeneuve, CHU Montpellier, 34295 Montpellier Cedex 5, France.
authors.forename: G
authors.initials: G
authors.lastname: Palenzuela
authors.forename: F
authors.initials: F
authors.lastname: Bernard
authors.forename: Q
authors.initials: Q
authors.lastname: Gardiner
authors.forename: M
authors.initials: M
authors.lastname: Mondain
mesh_terms: D000293:Adolescent; D002051:Burkitt Lymphoma / Q000209:etiology / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D007822:Laryngeal Neoplasms / Q000209:etiology* / Q000628:therapy*; D007828:Laryngoscopy; D016393:Lymphoma, B-Cell / Q000209:etiology* / Q000628:therapy*; D008297:Male; D018714:Radiotherapy, Adjuvant; D014923:Wiskott-Aldrich Syndrome / Q000150:complications*