title: Use of interventional procedures for peripheral arterial occlusive disease in Ontario between 1991 and 1998: a population-based study.
abstract: OBJECTIVE
  Although peripheral arterial occlusive disease (PAOD) is a public health issue in the elderly population, limited population-based data are available on use of interventional procedures in Canada. We describe trends in use of interventional procedures to treat PAOD in Ontario over the past decade.
  
  
  METHODS
  A retrospective population-based cohort study was conducted for fiscal years 1991 to 1998 with Ontario administrative databases to identify all arterial bypass surgeries, angioplasty procedures, and amputations performed.
  
  
  RESULTS
  A total of 19,332 bypass operations, 16,334 angioplasty procedures, and 17,534 amputations were identified. Population-based rates showed that angioplasty use peaked at about 110 per 100,000 at age 65 to 74 years, arterial bypass surgery use peaked at 129 per 100,000 at age 75 to 84 years, and amputation use peaked at 138 per 100,000 at age 85 years or older. All types of interventional procedures to treat PAOD were performed more frequently in men than in women. Age-adjusted and sex-adjusted rate of arterial bypass surgery decreased significantly, from 77 to 61 per 100,000 population aged 45 years or older (P =.0002, linear regression analysis), whereas rate for PTA increased significantly, from 59 to 75 per 100,000 population aged 45 years or older (P =.0005). The overall major amputation rate declined slightly over the study period, influenced by the decreased rate in patients aged 85 years or older. The revascularization rate in patients aged 85 years or older increased (P =.055).
  
  
  CONCLUSIONS
  Reduced use of arterial bypass surgery and increased use of angioplasty procedures has occurred over the past decade and may reflect a change in the practice pattern of vascular surgeons in Ontario, who have become more conservative in treating localized disease and reserve surgical interventions for more severe forms of PAOD. The slight reduction in overall major amputation rate, driven by decreased rate in patients aged 85 years or older, may reflect a trend toward a more aggressive revascularization approach in this age group.
authors.affiliation: Institute for Clinical Evaluative Science, University of Toronto, Sunnybrook and Women's College Health Science Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Omran
authors.forename: Jack V
authors.initials: JV
authors.lastname: Tu
authors.forename: K Wayne
authors.initials: KW
authors.lastname: Johnston
authors.forename: Muhammad M
authors.initials: MM
authors.lastname: Mamdani
authors.forename: Daryl S
authors.initials: DS
authors.lastname: Kucey
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000706:statistics & numerical data*; D017130:Angioplasty / Q000706:statistics & numerical data*; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D016491:Peripheral Vascular Diseases / Q000601:surgery*; D012189:Retrospective Studies; D017678:Sex Distribution