title: [Application of St George's respiratory questionnaire in evaluating the life quality of Chinese patients with chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  To study the value of St George's respiratory questionnaire (SGRQ) in evaluating the life quality of Chinese patients with COPD.
  
  
  METHODS
  The SGRQ score and spirometry were collected from 30 patients with COPD. The validity was documented by performing correlation analysis, and Pearson's correlation coefficients were calculated. Nineteen patients were reassessed after three months' treatment with inhaled glucocorticoids. Paired t test was performed to evaluate the sensitivity of SGRQ to changes of disease severity.
  
  
  RESULTS
  The correlation coefficients between the total score and the symptoms section score, the activity section score, and the impacts section score of SGRQ were 0.61, 0.79 and 0.97, respectively. The symptoms section score, the activity section score, the impacts section score, and the total score were significantly correlated with FEV(1)% pred, and with similar coefficients (-0.4 - -0.5, P < 0.05). The result of paired t test showed that the changes of SGRQ between the two assessments were significant (P < 0.001) and consistent with changes of clinical symptoms and spirometry. SGRQ was more sensitive than spirometry in evaluating the changes of disease severity.
  
  
  CONCLUSIONS
  SGRQ was a valid, sensitive and feasible method in measuring the quality of life in Chinese patients with COPD. Large-scale application in China needs to be carried out.
authors.affiliation: Department of Pulmonary Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: Wei-xuan
authors.initials: WX
authors.lastname: Lu
authors.forename: Yi-jie
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Bo
authors.initials: B
authors.lastname: Hu
authors.forename: Yi
authors.initials: Y
authors.lastname: Ma
authors.forename: Yuan-jue
authors.initials: YJ
authors.lastname: Zhu
mesh_terms: D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000503:physiopathology*; D011788:Quality of Life; D012129:Respiratory Function Tests; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires
chemical_list: D005938:Glucocorticoids