Urinary beta 2-microglobulin in premature infants with chorioamnionitis and chronic lung disease.
The urinary beta(2)-microglobulin (MG) concentration on day 0 to 2 was significantly higher in premature infants with chorioamnionitis (CAM) than in infants without CAM and in infants who developed chronic lung disease (CLD) than in those who did not. We propose that an elevated urinary beta(2)-MG can indicate a fetal inflammatory response and identify neonates at risk for the development of CLD.
Nishimaki
Shigeru
S
Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan. shigenis@med.yokohama-cu.ac.jp
Shima
Yoshio
Y
Sato
Miho
M
An
Hiromi
H
Hashimoto
Michiru
M
Nishiyama
Yoshiko
Y
Iwasaki
Shiho
S
Tateishi
Itaru
I
Seki
Kazuo
K
Yokota
Shumpei
S
D002821:Chorioamnionitis / Q000150:complications* / Q000652:urine*; D002908:Chronic Disease; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007677:Kidney Function Tests; D008171:Lung Diseases / Q000150:complications* / Q000652:urine*; D008297:Male; D009035:Mothers; D011247:Pregnancy; D011248:Pregnancy Complications; D012121:Respiration, Artificial; D001613:beta 2-Microglobulin / Q000652:urine*
D001613:beta 2-Microglobulin