title: [Clinical features of gastroesophageal reflux disease in geriatric patients].
abstract: OBJECTIVE
  To evaluate the features of gastroesophageal reflux disease (GERD) in elderly patients.
  
  
  METHODS
  72 patients with GERD were investigated for the history of illness and the results of gastroscopy and 24 hours esophageal bile monitoring of 54 patients were simultaneously randomized to undergo ambulatory pH monitoring. The degrees of esophagitis were graded according to endoscopic findings.
  
  
  RESULTS
  Obesity was found in 48% of the elderly group (more than 65 years old) and 49% of the control group (less than 65 years old). There were longer acid and bile reflux time and higher frequency (65%) of hiatal hernia in the elderly, and more patients (35%) had complicated severe grade esophagitis. There were longer time of bile reflux and the higher incidence (76%) of both acid and bile reflux in elderly group than in control group (P < 0.05). But the acid reflux time (%) was similar in two groups (P > 0.05).
  
  
  CONCLUSIONS
  The GERD in elderly patients may be associated with obesity and hiatal hernia. The features of elderly GERD patients are high frequency of erosive esophagitis, and high frequency of both acid and bile reflux, as well as longer history of bile reflux time.
authors.affiliation: Department of Gastroenterology, Tong Ren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Jia-li
authors.initials: JL
authors.lastname: Jiang
mesh_terms: D000367:Age Factors; D000368:Aged; D001655:Bile Reflux / Q000150:complications; D004942:Esophagitis, Peptic / Q000175:diagnosis; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000209:etiology; D005773:Gastroscopy; D006551:Hernia, Hiatal / Q000150:complications; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory; D009765:Obesity / Q000150:complications