[Inhibition of remineralization by EDTA-soluble phosphate protein in dentin].
OBJECTIVE
To investigate the effect of removing EDTA-soluble phosphate protein in dentin on the later remineralization for the purpose of better understanding of mechanism of dentin phosphate proteins on dentin mineralization.


METHODS
To remove soluble phosphate protein by EDTA dissolution, then the remineralization rate was monitored by a constant composition crystal growth technique. The results were compared with those from the normal dentin and the dentin partially demineralized by acetic acid.


RESULTS
Faster remineralization rates were found with dentin demineralized by EDTA (0.5 and 2 h) compared with normal dentin powder, while a slower rate was found with dentin demineralized by acetic acid. The increase of remineralization rate by removing phosphate protein from dentin was 100% more at 200 min after the start of the reaction.


CONCLUSIONS
EDTA-soluble phosphate protein in dentin has a great potential to inhibit remineralization.
Yu
Ling
L
Department of Stomatology, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
Gao
Xue-jun
XJ
Chen
Wan-chun
WC
Liu
Dao-dan
DD
D003739:Dental Cementum / Q000737:chemistry* / Q000378:metabolism; D003804:Dentin / Q000737:chemistry; D004492:Edetic Acid; D006801:Humans; D010750:Phosphoproteins / Q000032:analysis / Q000502:physiology*; D017001:Tooth Demineralization / Q000378:metabolism; D014089:Tooth Remineralization
D010750:Phosphoproteins; D004492:Edetic Acid