[Investigation on the gene expression pattern in cervical squamous cell carcinoma of uygur].
OBJECTIVE
To investigate the differentially expressed gene in cervical squamous cell carcinoma of uygur and normal cervical tissue using gene chip.


METHODS
Gene chips containing 2,048 human genes were used to investigate the gene expression pattern of 3 samples of cervical cancer.


RESULTS
By applying this gene chip we identified 64 differentially expressed genes in all 3 clinical cervical cancer samples, and we further identified 53 upregulated and 11 downregulated genes for functional analysis.


CONCLUSIONS
The analysis of gene expression pattern of tumor based on gene chip can realize high-throughput screening of the genes associated with the cervical cancer.
Liu
Kai-jiang
KJ
Department of Gynecologic Oncology, Affiliated Cancer Hospital of Xinjiang Medical University, Wulumuqi 830011, China.
Li
Ting-fang
TF
Zhao
Feng
F
Wang
Zhen-hua
ZH
Ge
Chong-hua
CH
Liu
Qing
Q
D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000378:metabolism; D002681:China; D005006:Ethnicity; D005260:Female; D015870:Gene Expression; D020869:Gene Expression Profiling; D015972:Gene Expression Regulation, Neoplastic; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D002583:Uterine Cervical Neoplasms / Q000235:genetics* / Q000378:metabolism
D005819:Genetic Markers