title: babA2- and cagA-positive Helicobacter pylori strains are associated with duodenal ulcer and gastric carcinoma in Brazil.
abstract: The babA2 and cagA genes were investigated in 208 Brazilian Helicobacter pylori strains. A strong association between babA2 and duodenal ulcer or gastric carcinoma was observed, even after adjusting for confounding factors, such as age, gender, and cagA status. cagA-positive strains were also independently associated with H. pylori-related diseases.
authors.affiliation: Laboratory of Research in Bacteriology, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Adriana Gonçalves
authors.initials: AG
authors.lastname: Oliveira
authors.forename: Adriana
authors.initials: A
authors.lastname: Santos
authors.forename: Juliana Becattini
authors.initials: JB
authors.lastname: Guerra
authors.forename: Gifone Aguiar
authors.initials: GA
authors.lastname: Rocha
authors.forename: Andreia Maria Camargos
authors.initials: AM
authors.lastname: Rocha
authors.forename: Celso Affonso
authors.initials: CA
authors.lastname: Oliveira
authors.forename: Mônica Maria Demas Alvares
authors.initials: MM
authors.lastname: Cabral
authors.forename: Ana Margarida Miguel Ferreira
authors.initials: AM
authors.lastname: Nogueira
authors.forename: Dulciene Maria Magalhães
authors.initials: DM
authors.lastname: Queiroz
mesh_terms: D018829:Adhesins, Bacterial / Q000235:genetics; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D001938:Brazil / Q000453:epidemiology; D002352:Carrier Proteins / Q000235:genetics; D004381:Duodenal Ulcer / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori / Q000235:genetics* / Q000472:pathogenicity; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D018829:Adhesins, Bacterial; D000942:Antigens, Bacterial; C400429:BabA protein, Helicobacter pylori; D001426:Bacterial Proteins; D002352:Carrier Proteins; C080866:cagA protein, Helicobacter pylori