title: Cefixime for the prophylaxis of urinary tract infections in children with malformative uropathies: an open study.
abstract: Urinary tract infections are often associated with urinary anomalies. An appropriate pharmacologic treatment may prevent, or may at least limit, any kidney damage due to pyelonephritis. The antibiotic prophylaxis plays a role as significant as early surgical therapy, taking into consideration also the present limitative trend for a softer therapeutic regimen. In the past few years a greater bacterial resistance has emerged against some commonly administered antibiotics. Cefixime (3rd generation cephalosporin) has been used on a wide series of patients suffering from urinary infections associated with urinary tract anomalies. A few significative results emerge from the present study. In conclusion, cefixime's effectiveness long-term prophylaxis of urinary infections associated with anomalies.
authors.affiliation: Struttura Complessa di Chirurgia Pediatrica, Azienda Ospedaliera Pugliese Ciaccio - Catanzaro, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Stranieri
authors.forename: S
authors.initials: S
authors.lastname: Zampogna
authors.forename: V
authors.initials: V
authors.lastname: Ielapi
authors.forename: R G
authors.initials: RG
authors.lastname: Defilippo
authors.forename: V
authors.initials: V
authors.lastname: Defilippo
authors.forename: G
authors.initials: G
authors.lastname: Cristofaro
authors.forename: R
authors.initials: R
authors.lastname: Galiano
authors.forename: S
authors.initials: S
authors.lastname: Capillo
authors.forename: L
authors.initials: L
authors.lastname: Madonna
authors.forename: S
authors.initials: S
authors.lastname: Cifalà
authors.forename: V
authors.initials: V
authors.lastname: Ferro
authors.forename: R
authors.initials: R
authors.lastname: Rubino
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use*; D020682:Cefixime / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*; D014564:Urogenital Abnormalities / Q000150:complications / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D020682:Cefixime