Body mass index and uterine receptivity in the oocyte donation model.
OBJECTIVE
To evaluate the relationship of body mass index (BMI) to uterine receptivity under conditions of programmed hormonal support and standardized embryo quality.


METHODS
Retrospective cohort study.A tertiary referral center.


METHODS
Ninety-seven consecutive first-cycle recipients of anonymous oocyte donation. After programmed hormone replacement, recipients had transfer of embryos derived from oocyte donation. Anonymous oocyte donors received ovarian stimulation and underwent transvaginal ultrasound-guided oocyte retrieval.


METHODS
A receiver operator characteristic (ROC) curve of implantation versus BMI. Area under the ROC curve was 0.51, 95% confidence interval (CI) 0.41-0.62, suggesting no relationship between BMI and implantation. There was no difference in implantation rates between obese (BMI >or=30) and nonobese (BMI <30) recipients, odds ratio 1.1, 95% CI 0.5-2.4.


CONCLUSIONS
Uterine receptivity was unimpaired in women with increased BMI when hormonal support and embryo quality were standardized.
Wattanakumtornkul
Saranya
S
Mayo Clinic, Rochester, Minnesota 55905, USA.
Damario
Mark A
MA
Stevens Hall
Sharon A
SA
Thornhill
Alan R
AR
Tummon
Ian S
IS
D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D016017:Odds Ratio; D018587:Oocyte Donation; D012372:ROC Curve; D012189:Retrospective Studies; D016896:Treatment Outcome; D014599:Uterus / Q000503:physiopathology*