title: Nanocantilever signal transduction by electron transfer.
abstract: Microfabricated cantilever beams promise to bring about a revolution in the field of chemical, physical, and biological sensor development. The resonance frequency of a microfabricated cantilever shifts sensitively because of mass loading from molecular adsorption. The minimum detectable adsorbed mass on a cantilever sensor can be increased by orders of magnitude by changing the dimensions of the device; smaller and thicker cantilevers offer higher resonance frequency and therefore better mass detection sensitivity. Here we describe micromachined silicon cantilevers that are 0.5 to 4 microns in length, fabricated with the use of a focused ion beam (FIB). In addition, we demonstrate a technique for detection of the cantilever resonance frequency that is based on electron transfer.
authors.affiliation: Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
authors.forename: P G
authors.initials: PG
authors.lastname: Datskos
authors.forename: T
authors.initials: T
authors.lastname: Thundat
mesh_terms: D003460:Crystallization / Q000379:methods*; D004548:Elasticity; D004563:Electrochemistry / Q000379:methods; D004581:Electronics / Q000295:instrumentation* / Q000379:methods; D004583:Electrons; D004735:Energy Transfer; D004867:Equipment Design; D009038:Motion; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D012825:Silicon / Q000737:chemistry* / Q000528:radiation effects; D013314:Stress, Mechanical; D014159:Transducers; D014173:Transistors, Electronic
chemical_list: D012825:Silicon