title: Do sex and race/ethnicity influence CD4 cell response in patients who achieve virologic suppression during antiretroviral therapy?
abstract: To determine whether CD4 cell count response to virus suppression during highly active antiretroviral therapy differs according to sex or race/ethnicity, we analyzed data in our observational cohort study for patients receiving their first antiretroviral regimen who experienced virus suppression by 6 months of therapy. In both univariate and multivariate analyses, women had greater CD4 cell count increases, compared with men, as did patients receiving a regimen that did not include a protease inhibitor. Race/ethnicity was not a factor.
authors.affiliation: Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA. tpg@bcm.tmc.edu
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Giordano
authors.forename: John A
authors.initials: JA
authors.lastname: Wright
authors.forename: Mirza Q
authors.initials: MQ
authors.lastname: Hasan
authors.forename: A Clinton
authors.initials: AC
authors.lastname: White
authors.forename: Edward A
authors.initials: EA
authors.lastname: Graviss
authors.forename: Fehmida
authors.initials: F
authors.lastname: Visnegarwala
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D006678:HIV / Q000187:drug effects / Q000502:physiology; D015658:HIV Infections / Q000188:drug therapy / Q000208:ethnology / Q000276:immunology*; D006801:Humans; D008297:Male; D012737:Sex Factors
chemical_list: D019380:Anti-HIV Agents