title: Synthesis of 2-(pyrimidin-4-yl)indoles.
abstract: The synthesis of 2-substituted isomers of the meridianins, a familiy of bioactive indole alkaloids isolated from the tunicate Aplidium meridianum, was undertaken. The synthetic route comprises six steps, with a microwave promoted Fischer cyclization as the key reaction.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
authors.forename: Laura Hernández
authors.initials: LH
authors.lastname: Franco
authors.forename: Jorge Alejandro
authors.initials: JA
authors.lastname: Palermo
mesh_terms: D000818:Animals; D026121:Indole Alkaloids / Q000138:chemical synthesis; D007211:Indoles / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*; D014561:Urochordata
chemical_list: D026121:Indole Alkaloids; D007211:Indoles; D011743:Pyrimidines; C030986:pyrimidine