Structure of human vertebral lamellar bone in age-associated involution and osteoporosis.
We compared the structure of lamellar bone in anterolateral zones of vertebral bodies in adult and senile subjects in health and osteoporosis. The appearance of structural signs of age-related osteopenia and enlargement of coplanar consolidations of the bone matrix crystals were noted. Osteopenia was more pronounced in osteoporosis, while the structural organization of the mineral component did not differ from that in age-matched controls.
Zhilkin
B A
BA
Department of Morphology, VILAR Research, Training, and Methodological Center of Biomedical Technologies, Moscow.
Doktorov
A A
AA
Denisov-Nikol'skii
Yu I
YI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002113:Calcification, Physiologic; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis / Q000473:pathology*; D013131:Spine / Q000473:pathology* / Q000648:ultrastructure*