Recent advances in Helicobacter pylori infection in children: from the petri dish to the playground.
Helicobacter pylori infection is acquired in childhood, plays a causative role in chronic gastritis and peptic ulcer disease, and is associated with the development of gastric cancer. The present review focuses on recent advances in the scientific knowledge of H pylori infection in children, including clinical sequelae, diagnosis and treatment. In addition, recent insights regarding both bacterial and host factors that mediate human diseases associated with H pylori infection are discussed.
Zheng
Peng-Yuan
PY
University of Toronto, Toronto, Canada.
Jones
Nicola L
NL
D018829:Adhesins, Bacterial / Q000502:physiology; D001426:Bacterial Proteins / Q000502:physiology; D001427:Bacterial Toxins; D001944:Breath Tests; D002352:Carrier Proteins / Q000502:physiology; D002648:Child; D004415:Dyspepsia / Q000150:complications; D016481:Helicobacter Infections / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D016480:Helicobacter pylori; D006801:Humans; D007375:Interleukin-1 / Q000502:physiology; D013274:Stomach Neoplasms / Q000209:etiology; D013601:T-Lymphocytes / Q000502:physiology
D018829:Adhesins, Bacterial; C400429:BabA protein, Helicobacter pylori; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D002352:Carrier Proteins; D007375:Interleukin-1; C074689:VacA protein, Helicobacter pylori