title: [Surgical intervention of hepatocellular carcinoma with bile duct thrombi].
abstract: OBJECTIVE
  To summarize the experience of surgical intervention for hepatocellular carcinoma (HCC) with bile duct thrombi (BDT), and to evaluate the influence on prognosis.
  
  
  METHODS
  From 1994 to 2002, 15 patients with HCC and BDT who underwent surgical intervention were retrospectively analyzed.
  
  
  RESULTS
  The operative procedures included hepatectomy with removal of BDT (n = 7), hepatectomy combined with extrahepatic bile duct resection (n = 4), thrombectomy through choledochotomy (n = 3), and piggy-back orthotopic liver transplantation (n = 1). The 1- and 3-year survival rates were 73.3% and 40%, respectively. Two patients survived over 5 year. The survival rate of patients with portal vein invasion was significantly lower than that of patients without portal vein invasion (P < 0.05).
  
  
  CONCLUSIONS
  Surgical intervention was effective for patients with HCC and BDT. Operation after recurrence can prolong the survival time. Liver transplantation is a new operative procedure worthy of study.
authors.affiliation: Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009 China.
authors.forename: Shu-you
authors.initials: SY
authors.lastname: Peng
authors.forename: Jian-wei
authors.initials: JW
authors.lastname: Wang
authors.forename: Ying-bin
authors.initials: YB
authors.lastname: Liu
authors.forename: Xiu-jun
authors.initials: XJ
authors.lastname: Cai
authors.forename: Yi-ping
authors.initials: YP
authors.lastname: Mou
authors.forename: Yu-lian
authors.initials: YL
authors.lastname: Wu
authors.forename: He-qing
authors.initials: HQ
authors.lastname: Fang
authors.forename: Cheng-hong
authors.initials: CH
authors.lastname: Peng
mesh_terms: D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000601:surgery*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013927:Thrombosis / Q000601:surgery*