[Single-lung transplantation for end-stage emphysema].
OBJECTIVE
To evaluate operative technique, patient selection and perioperative management of single-lung transplantation for a patients with end-stage emphysema.


METHODS
A 56-year-old patient with end-stage emphysema underwent left-lung transplantation on September 28, 2002. The surgical technique used was similar to that mentioned in the literature. The donor lung was perfused by LPD solution with a cold ischemic time of 260 minutes. Cardiopulmonary bypass was not performed.


RESULTS
The patient weaned from a ventilator at the 93th hour after operation. Immunosuppressants included cyclosporine, mycophenolate mofetil and corticosteroid. Acute rejection occurred on the ninth day after operation and was cured by bolus methylprednisolone given intravenously. Lung function was improved significantly and the patient was discharged from the hospital on the 47th day after operation.


CONCLUSIONS
Single-lung transplantation for patients with end-stage emphysema is effective for long-term improvement of pulmonary function.
Chen
Jing-yu
JY
Department of Thoracic Surgery, Wuxi Fifth People's Hospital, Wuxi 214073, China.
Zheng
Ming-feng
MF
He
Yi-jun
YJ
Zhu
Qian-kun
QK
Hu
Chun-xiao
CX
Chen
Ruo
R
Zhu
Da-wei
DW
Su
Zheng-xing
ZX
Ye
Shu-gao
SG
D000328:Adult; D004646:Emphysema / Q000601:surgery*; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged