What is the magnitude of the subpopulation effect?
The effect of population subdivision on estimated match probabilities has been raised [Nature 339 (1989) 501; Am. J. Hum. Genet. 48 (1991) 819; Science 254 (1991) 1921]. Previous work [J. Forensic Sci. 39 (1994) 319; J. Forensic Sci. 39 (1994) 988; Am. J. Hum. Genet. 55 (1994) 533] has compared product rule estimates from differing databases and found that the "subpopulation" error may be of the order of a factor of 10. This approach compares an estimate with an estimate. This paper uses simulation to extend these studies by allowing a comparison to a 'true match probability' and supports the conclusion that subpopulation effects are mild. In addition the performance of recommendations 4.1 and 4.2 of NRC II [National Research Council and C.O.D.F. Science, The Evaluation of Forensic DNA Evidence, National Academy Press, Washington, DC, 1996].
Curran
James M
JM
Department of Statistics, University of Waikato, Hamilton, New Zealand. curran@stat.waikato.ac.nz
Buckleton
John S
JS
Triggs
Christopher M
CM
D003241:Consanguinity; D004247:DNA / Q000235:genetics*; D016208:Databases, Factual; D005828:Genetics, Population; D006801:Humans; D015203:Reproducibility of Results; D020080:Tandem Repeat Sequences
D004247:DNA