Exacerbation of Crohn's disease after insertion of a levonorgestrel intrauterine system: a case report.
The case report describes a relapse of Crohn's disease in a woman soon after the fitting of a levonorgestrel intrauterine system (IUS). Whilst the published evidence on the effects of levonorgestrel IUS in patients with pre-existing inflammatory bowel disease is limited, reports to date suggest that caution should be exercised when considering fitting an IUS in such women, even if there appears to be much to gain from an expected reduction in menorrhagia.
Wakeman
Jacqueline
J
Langton Medical Group, St Chad Health Centre, Lichfield, UK.
D000328:Adult; D000842:Ankle; D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000009:adverse effects*; D003424:Crohn Disease / Q000139:chemically induced* / Q000503:physiopathology; D004487:Edema / Q000139:chemically induced; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects*; D016912:Levonorgestrel / Q000008:administration & dosage / Q000009:adverse effects*; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors; D016896:Treatment Outcome
D003271:Contraceptive Agents, Female; D045167:Progesterone Congeners; D016912:Levonorgestrel