[Meta-analysis of the relationship between smoking and stomach cancer].
OBJECTIVE
To explore the risk of stomach cancer associated with cigarette smoking.


METHODS
Meta-analysis was used to make formal summary statements about the relationship between smoking and stomach cancer. The results of the studies were analyzed by studied type(case-control study and cohort study) and gender(male and female). Homogeneity showed that random effect model should be selected to calculate the pooling relative risk (RR) and its corresponding 95% confidence interval (95%CI).


RESULTS
The total pooling RR(95%CI) was 2.14(1.12-4.06), while the total pooling RRs (95%CI) of male and female smoking with stomach cancer were 1.70 (1.34-2.14) and 1.83 (0.10-33.09), respectively.


CONCLUSIONS
Cigarette smoking is a risk factor for stomach cancer. Male smoking can increase risk of stomach cancer, however, the relationship between female smoking and stomach cancer should be studied further.
Liu
Yun-xia
YX
Institute of Evidence-Based Medicine, Shandong University, Jinan 250012, China. yunxialiu@163.com
Wang
Jie-zhen
JZ
D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects*; D013274:Stomach Neoplasms / Q000209:etiology*