[Guideline for hyperlipidemia].
The guideline for hyperlipidemia was first discussed at the meeting of the Japan Atherosclerosis Society in 1987 and further discussed and published for the first time by the Society in 1997. Thereafter, a new guideline "Japan Atherosclerosis Society(JAS) Guidelines for Diagnosis and Treatment of Atherosclerotic Cardiovascular Diseases" was released in September 2002 taking the results of J-LIT study and others into consideration. The diagnostic values of TC, LDL-C, HDL-C and TG for hyperlipidemia are > or = 220 mg/dl, > or = 140 mg/dl, < 40 mg/dl, and > or = 150 mg/dl, respectively, the same figures as those of a previous guideline in 1997. Other criteria were made as management goals for patients with coronary heart disease in each category, classified by the number of risk factors. According to the criteria, the recommended level of TC is < 240 mg/dl in males aged less than 45 with no risk factors. If any result is abnormal, treatment by life style and dietary modification should be started first and drug therapy should be a second choice. It should be noted that this guideline helps to inform, not replace, the physician's clinical judgement, which must ultimately determine the appropriate treatment for each individual.
Seishima
Mitsuru
M
Department of Clinical Laboratory Medicine, Gifu University School of Medicine, Gifu 500-8705.
D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control; D005247:Feeding Behavior; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008019:Life Style; D008055:Lipids / Q000097:blood; D008297:Male; D017410:Practice Guidelines as Topic; D012307:Risk Factors
D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D008055:Lipids