Changes of resistance parameters of femoral bone in adult female rats after application of zoladex and vincristin.
The study consisted in testing the influence of vincristin and zoladex on mechanical resistance of the femur bone in adult female rats. Vincristin was administered intraperitoneally and zoladex--subcutaneously. The experiments imply that in the group of animals receiving vincristin the bone resistance decreased by 6.4% as compared to the control group, and in the group of animals receiving zoladex--by 14.3%.
Nadulska
Anna
A
Department of Human Physiology, Medical University of Lublin.
Klukowska
Lidia
L
Dyba
Stefan
S
D000818:Animals; D019245:Compressive Strength / Q000187:drug effects / Q000502:physiology; D005260:Female; D005264:Femoral Fractures / Q000503:physiopathology; D005269:Femur / Q000187:drug effects* / Q000502:physiology*; D017273:Goserelin / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D013314:Stress, Mechanical; D014750:Vincristine / Q000633:toxicity*; D016474:Weight-Bearing / Q000502:physiology*
D017273:Goserelin; D014750:Vincristine