Successful treatment of primary non-Hodgkin's lymphoma of the vagina with chemotherapy.
BACKGROUND
The vagina as a primary site of malignant lymphoma in woman is extremely rare.


METHODS
We report here a 30-year-old patient with a primary vaginal non-Hodgkin's lymphoma stage IEA, follicular large cell of B lineage, with an excellent response to cytotoxic chemotherapy (CHOP) and event-free survival of 28 months.


CONCLUSIONS
Primary involvement of the vagina can be successfully treated by pelvic irradiation, but in young women chemotherapy should be considered to preserve fertility, as well as quality of life.
Engin
Hüseyin
H
Department of Medical Oncology, Hacettepe University Oncology Institute, 06100 Sihhiye, Ankara, Turkey. hengin@hacettepe.edu.tr
Türker
Alev
A
Abali
Hüseyin
H
Uner
Ayşegül
A
Günalp
Serdar
S
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008224:Lymphoma, Follicular / Q000175:diagnosis* / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone