title: [Oral chemolysis of uric acid stones].
abstract: Oral chemolysis of uric acid stones was performed retrospectively. Twenty-one patients with upper urinary uric acid stones were given alkaline citrate (Uralyt-U) orally. In the case of hyperuicemia, allopirinol was combined. In 11 out of 15 patients (73.3%) treated with oral chemolysis alone, stones were dissolved. In 4 out of 6 cases (66.7%) combined with extracorporeal shock-wave lithotripsy, administration of alkaline citrate shortened the period to be stone-free. In conclusion, we successfully treated 15 out of 21 cases (71.4%) with the administration of alkaline citrate.
authors.affiliation: Department of Urology, Osaka Police Hospital.
authors.forename: Masahito
authors.initials: M
authors.lastname: Honda
authors.forename: Keisuke
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Chikahiro
authors.initials: C
authors.lastname: Momohara
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Komori
authors.forename: Tuyoshi
authors.initials: T
authors.lastname: Takada
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujioka
mesh_terms: D000284:Administration, Oral; D000493:Allopurinol / Q000627:therapeutic use; D019343:Citric Acid / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D006801:Humans; D033461:Hyperuricemia / Q000150:complications / Q000188:drug therapy; D008096:Lithotripsy; D012189:Retrospective Studies; D016896:Treatment Outcome; D014527:Uric Acid / Q000032:analysis*; D014545:Urinary Calculi / Q000737:chemistry / Q000150:complications / Q000628:therapy*
chemical_list: D014527:Uric Acid; D019343:Citric Acid; D000493:Allopurinol