Mechanism of synergism between sympathetic and parasympathetic autonomic nervous systems in the regulation of motility of the stomach and sphincter of Oddi.
The mechanisms of stimulatory effect of the sympathetic trunk on gastric motor activity and vagal inhibitory effect on electromotor activity of the sphincter of Oddi were studied. Gastric contractions were augmented by preganglionic serotoninergic fibers related synaptically to serotoninergic neurons, while inhibition of electromotor activity of the sphincter of Oddi was elicited by activation of alpha- and beta-adrenoceptors.
Smirnov
V M
VM
Department of Normal Physiology, Russian State Medical University, Moscow.
Lychkova
A E
AE
D000818:Animals; D004285:Dogs; D005730:Ganglionic Blockers / Q000494:pharmacology; D005769:Gastrointestinal Motility / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011817:Rabbits; D012701:Serotonin / Q000502:physiology; D009803:Sphincter of Oddi / Q000294:innervation / Q000502:physiology*; D013270:Stomach / Q000294:innervation / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000502:physiology*; D014630:Vagus Nerve / Q000502:physiology
D005730:Ganglionic Blockers; D012701:Serotonin