[Positive potentials of the human brain at different stages of preparation of a visually triggered saccade].
The EEG of 10 right-handed subjects preceding saccades with mean values of latent periods were selected and averaged. Two standard paradigms of presentation of visual stimuli (central fixation stimulus-peripheral target succession): with a 200-ms inerstimulus interval (GAP) and successive single step (SS). During the period of central fixation, two kinds of positive potentials were observed: fast potentials of "inermediate" positivity (IP) developing 600-400 ms prior to saccade onset and fast potentials of "leading" positivity (LP), which immediately preceded the offset of the central fixation stimulus. Peak latency of the LP potentials was 300 ms prior to saccade onset in the SS paradigm and 400 ms in the GAP paradigm. These potentials were predominantly recorded in the frontal and frontosagittal cortical areas. Decrease in the latency by 30-50 ms in the GAP paradigm was associated with more pronounced positive potentials during the fixation period and absence of the initiation potential P-1' (or decrease in its amplitude). The obtained evidence suggest that the fast positive presaccadic potentials are of a complex nature related to attention, anticipation, motor preparation, decision making, saccadic initiation, and backward afferentation.
Slavutskaia
M V
MV
Department of Higher Nervous Activity, Lomonosov State University, Moscow. slav@protein.bio.msu.ru
Shul'govskiĭ
V V
VV
D000328:Adult; D001288:Attention; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography; D018913:Event-Related Potentials, P300; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005403:Fixation, Ocular; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*