title: Sevelamer.
abstract: Hyperphosphataemia in patients with chronic renal failure has traditionally been treated with calcium- and aluminium-containing phosphate binders. This article briefly discusses the rationale and complications of these treatments and reviews sevelamer that is a novel non-calcium-, non-aluminium-containing phosphate binder and the evidence to support its use in clinical practice.
authors.affiliation: Oxford Kidney Unit, Churchill Hospital, Oxford, UK.
authors.forename: Jane
authors.initials: J
authors.lastname: Henderson
authors.forename: Paul
authors.initials: P
authors.lastname: Altmann
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004852:Epoxy Compounds / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000188:drug therapy*; D010710:Phosphates / Q000097:blood* / Q000378:metabolism; D011073:Polyamines; D011095:Polyethylenes / Q000378:metabolism / Q000627:therapeutic use*; D000069603:Sevelamer
chemical_list: D004852:Epoxy Compounds; D010710:Phosphates; D011073:Polyamines; D011095:Polyethylenes; D000069603:Sevelamer