title: Immobilization of sun bears (Helarctos malayanus) with medetomidine-zolazepam-tiletamine.
abstract: A mixture of medetomidine (50.0 microg/kg, i.m.) and zolazepam-tiletamine (2.0 mg/kg, i.m.) effectively immobilized 16 sun bears (Helarctos malayanus) for more than 1 hr with good myorelaxation and minimal effects on cardiorespiratory performance during 22 immobilizations. All bears were immobilized once, except for six individuals that were immobilized twice. Atipamezole (250 microg/kg, i.v.) effectively reversed medetomidine-induced sedation and reduced recovery time significantly. Respiratory rates of immobilized bears did not change significantly over time. Rectal body temperature and heart rate decreased significantly after 10 min of immobilization. Hematologic and serum biochemical parameters did not change significantly within 30 min of induction.
authors.affiliation: Semenggoh Wildlife Rehabilitation Center, Sarawak Forestry Department Wisma Sumber Alam, Jalan Stadium, Kuching, Sarawak 93660, Malaysia.
authors.forename: Manabu
authors.initials: M
authors.lastname: Onuma
mesh_terms: D019162:Anesthetics, Combined; D000778:Anesthetics, Dissociative; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives; D007103:Immobilization; D008297:Male; D020926:Medetomidine / Q000008:administration & dosage; D012119:Respiration / Q000187:drug effects; D013992:Tiletamine / Q000008:administration & dosage; D001503:Ursidae / Q000502:physiology*; D015041:Zolazepam / Q000008:administration & dosage
chemical_list: D019162:Anesthetics, Combined; D000778:Anesthetics, Dissociative; D006993:Hypnotics and Sedatives; D013992:Tiletamine; D015041:Zolazepam; D020926:Medetomidine