title: Simple and efficient protocol for the synthesis of functionalized styrenes from 1,2-dibromoethane and arylboronic acids.
abstract: [reaction: see text] A simple and efficient protocol for the preparation of functionalized styrenes is disclosed that employs the palladium-catalyzed cross-coupling reaction of arylboronic acids with vinyl bromide, generated in situ from 1,2-dibromoethane. The reaction is carried out under mild reaction conditions. Compared with the cross-coupling reactions usually employed to obtain vinylarenes, this protocol is very simple, overcomes the inconvenience of using of ethylene under pressure, and uses air-stable and widely available arylboronic acids instead of vinyl organometallic reagents.
authors.affiliation: Laboratory of Molecular Catalysis, Instituto de Química, UFRGS, Av. Bento Gonçalves, 9500 Porto Alegre 91501-970, CP 15003, RS, Brazil.
authors.forename: Vanusa R
authors.initials: VR
authors.lastname: Lando
authors.forename: Adriano L
authors.initials: AL
authors.lastname: Monteiro