Intermolecular radical addition and addition/cyclization reactions of alkoxyamines onto nonactivated alkenes.
[reaction: see text] Alkoxyamines A, which are readily prepared from commercially available starting materials, undergo efficient thermal radical carboaminoxylations onto various nonactivated alkenes to provide 1,4-functionalized malonates B in good to excellent yields. The experiments are very easy to conduct. The carboaminoxylations can be combined with radical cyclization and fragmentation processes.
Wetter
Christian
C
Department of Chemistry, Philipps-University Marburg, 35032 Marburg, Germany.
Jantos
Katja
K
Woithe
Katharina
K
Studer
Armido
A