title: [Extemporaneous examination of the sentinel lymph node in breast cancer: is the glass half full or half empty?].
abstract: Intra-operative examination of sentinel LN is controversial. Concordance with definitive exam of SLN in this series was 81%, though only 54% of positive cases were diagnosed. Micrometastases and ITC were usually lost intraoperatively, accounting for 14% of cases. Frozen section and touch prep of the SLN were approximately equivalent. The latter has the advantage of preserving tissue for step-analysis of SLN. The ultimate method of intraoperative analysis of SLN which can combine cost-effectiveness and accuracy needs to be determined.
authors.affiliation: Dipartimento di Chirurgia, Ospedale MG Vannini, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Fortunato
authors.forename: M
authors.initials: M
authors.lastname: Amini
authors.forename: M
authors.initials: M
authors.lastname: Farina
authors.forename: S
authors.initials: S
authors.lastname: Rapacchietta
authors.forename: L
authors.initials: L
authors.lastname: Costarelli
authors.forename: F
authors.initials: F
authors.lastname: Piro
authors.forename: G
authors.initials: G
authors.lastname: Alessi
authors.forename: P
authors.initials: P
authors.lastname: Pompili
authors.forename: S
authors.initials: S
authors.lastname: Bianca
authors.forename: C E
authors.initials: CE
authors.lastname: Vitelli
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D005188:False Negative Reactions; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007150:Immunohistochemistry; D007430:Intraoperative Care; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D008408:Mastectomy; D008875:Middle Aged; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy