title: Chemo- and regio-selective modifications of nucleic acids by acetaldehyde and crotonaldehyde.
abstract: The reactions of guanine nucleosides and nucleotides with acetaldehyde or crotonaldehyde were significantly accelerated even under mild conditions by the presence of a basic amino acid such as arginine and lysine to form smoothly and selectively the corresponding cyclic 1,N2-propano adducts.
authors.affiliation: Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan.
authors.forename: Magoichi
authors.initials: M
authors.lastname: Sako
authors.forename: Isamu
authors.initials: I
authors.lastname: Yaekura
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Deyashiki
mesh_terms: D000079:Acetaldehyde / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D009696:Nucleic Acids / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D009696:Nucleic Acids; C012796:2-butenal; D000079:Acetaldehyde