title: Commissural dehiscence and pannus formation of porcine heart valve bioprostheses.
abstract: From May 1976 to June 2001, 95 porcine heart valve bioprostheses (BPs) were explanted. Among them, 85 prostheses were available for an analysis of structural valve deterioration (SVD). There were 32 Hancock (H) BPs and 53 Carpentier-Edwards (CE) BPs, with a mean implantation duration of 12 +/- 3.5 and 11.0 +/- 4 years, respectively. There were two extraordinary complications. One was commissural dehiscence (CD) of the CEBPs in 10/53 cases (18.9%), with a mean duration of 12.7 +/- 2.7 years. This was not observed in the HBPs. The other was pannus formation in both BPs. In the mitral position, it was 25/32 (78.1%) in HBPs and 37/53 (69.8%) in CEBPs. In the aortic position, it was 4/32 (1.3%) in the HBPs and 11/53 (20.8%) in the CEBPs. We conclude that CD could not be diagnosed preoperatively and anticoagulation is therefore indicated to prevent pannus formation of such prostheses, particularly in those located in the mitral position.
authors.affiliation: Department of Cardiovascular Surgery, Fukuoka University School of Medicine, Kasuya Fukuoka, Japan. shinge@minf.med.fukuoka-u.ac.jp
authors.forename: Michio
authors.initials: M
authors.lastname: Kimura
authors.forename: Akio
authors.initials: A
authors.lastname: Iwakuma
authors.forename: Noritsugu
authors.initials: N
authors.lastname: Morishige
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Nakamura
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tachikawa
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Shibano
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Iwahashi
authors.forename: Ryuji
authors.initials: R
authors.lastname: Zaitsu
authors.forename: Tadashi
authors.initials: T
authors.lastname: Motomura
authors.forename: Kazuma
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Tadashi
authors.initials: T
authors.lastname: Tashiro
authors.forename: Katsushi
authors.initials: K
authors.lastname: Kitasato
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D002114:Calcinosis; D005260:Female; D006349:Heart Valve Diseases / Q000473:pathology; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013529:Surgical Wound Dehiscence; D013552:Swine