title: Surfactant driven flows overlying a hydrophobic epithelium: film rupture in the presence of slip.
abstract: Both for tear films and along the airways within the lung, one has an extremely thin fluid layer overlying a biological substrate; in both cases surfactants either of natural origin, or artificially introduced, are important in driving fluid flows. There is evidence that slip can occur when hydrophilic liquids, similar to mucus or aqueous tear films, overlie hydrophobic epithelium. Utilizing results from recent experimental findings we examine the possible influence of slip upon tear film rupture, important in so-called dry eye, and upon surfactant-induced flows within the lung, used in surfactant replacement therapy.
authors.affiliation: Department of Chemical Engineering and Chemical Technology, Imperial College of Science, Technology and Medicine, London SW7 2BY, UK.
authors.forename: Yong Liang
authors.initials: YL
authors.lastname: Zhang
authors.forename: Richard V
authors.initials: RV
authors.lastname: Craster
authors.forename: Omar K
authors.initials: OK
authors.lastname: Matar
mesh_terms: D004848:Epithelium / Q000737:chemistry* / Q000502:physiology; D057927:Hydrophobic and Hydrophilic Interactions; D008954:Models, Biological; D020545:Respiratory Mucosa / Q000737:chemistry; D013500:Surface Tension; D013501:Surface-Active Agents / Q000737:chemistry*; D013666:Tears / Q000737:chemistry
chemical_list: D013501:Surface-Active Agents