Experimental study of nerve graft with vascular implantation.
OBJECTIVE
To study the performance of free nerve graft with vascular implantation.


METHODS
Three groups of rats were used. A 10 mm nerve defect was made in the sciatic nerve. It was repaired respectively with vascularised nerve graft (VNG), free nerve graft with vascular implantation (NGV) or free nerve graft (NG). Before 30 days the revascularisation of the nerve graft was assessed; at 2 to 3 month regeneration of nerve was evaluated. Histochemical staining, vascular morphology and electrophysiological examination were undertaken.


CONCLUSIONS
The number of regenerated blood vessels in VNG and NGV was significantly increased than that in NG before 30 days. The ratio of regenerated nerve fiber area and conduction velocity in the first two groups were much better than those in NG at 2 to 3 months.
Haiming
D
D
Department of Orthopedics, Shan Xi Medical University, Tai Yuan 030001.
Xicheng
H
H
Houshan
L
L
Baoguo
J
J
Chuanhan
F
F
D000818:Animals; D002196:Capillaries; D009412:Nerve Fibers / Q000473:pathology; D009416:Nerve Regeneration; D016067:Nerve Transfer; D009431:Neural Conduction; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000098:blood supply / Q000503:physiopathology / Q000601:surgery*