Comparative analysis of the gasometric and hemodynamic parameters in preoperative evaluation of patients with lung cancer.
Measurements including spirographic examination, arterial blood gas tensions, standard electrocardiogram are routinely used to define risk factors for patients undergoing lung tissue resection. In some instances routine functional check-ups should be accompanied by the assessment of the hemodynamics of pulmonary circulation. The purpose of the study was to evaluate the correlations between gasometric and hemodynamic parameters measured at rest and after exercise. In case of the presence of such correlations I wanted to find the principles to provide pulmonary artery hypertension in order to avoid right heart catheterization. The gasometric parameters in systemic and in mixed venous blood (pH, PaO2, PaCO2, SaO2) as well as hemodynamic parameters of pulmonary circulation (PAP, PCWP, CVP) were measured in 50 male patients with lung carcinoma. All measurements were taken at rest and after an exercise test--5 minutes, 50 W workload on cycle ergometer in supine position. CI, PVR and SVR were calculated. The study proved statistically significant correlations between gasometric and hemodynamic parameters and made possible to calculate the regression lines equations, which help to predict pulmonary artery pressure before tissue resection.
Stazka
Janusz
J
Department of Cardiac Surgery, Medical University of Lublin.
D000328:Adult; D000368:Aged; D001784:Blood Gas Analysis; D002283:Carcinoma, Bronchogenic / Q000503:physiopathology / Q000601:surgery*; D006305:Health Status Indicators; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008175:Lung Neoplasms / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000503:physiopathology / Q000517:prevention & control; D011300:Preoperative Care; D011379:Prognosis; D012016:Reference Values; D012680:Sensitivity and Specificity