title: Discovery of a novel route to 2'-deoxy and 2'-functional pyrimidine nucleosides via 3',5'-O-sulfinyl xylo-nucleosides.
abstract: We synthesized 2,2'-anhydro-pyrimidine nucleosides through a novel and efficient rearrangement with 3',5'-O-sulfinyl xylo nucleosides which were prepared from an inexpensive starting material, D-xylose. A variety of 2'-deoxy and 2'-functional pyrimidine nucleosides can be prepared from 2,2'-anhydro-pyrimidine nucleosides.
authors.affiliation: Ichikawa Research Institute, Kobayashi Perfumery CO., LTD., 4-12-1 Ohwada, Ichikawa-City 272-0025, Japan.
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Takatsuki
authors.forename: Shigeo
authors.initials: S
authors.lastname: Kohmoto
authors.forename: Keiki
authors.initials: K
authors.lastname: Kishikawa
authors.forename: Haruhiro
authors.initials: H
authors.lastname: Yamashita
authors.forename: Makoto
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011741:Pyrimidine Nucleosides