title: Conformational change of hydroxyapatite/gelatin nanocomposite by glutaraldehyde.
abstract: The hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was prepared through the coprecipitation and then cross-linked by using glutaraldehyde (GA). From FT-IR measurement the spectral features for amide bands and phosphate bands were severely modified by the cross-linkage and the organic content increased with the degree of cross-linkage. From Transmission Electron Microscopy (TEM) and electron diffraction analyses we could confirm the preferentially directional growth of needle-like HAp particles, which were embedded in GEL by the mineralization. Also we could observe worm-like stria patterns of contrast, which were revealed by the mineralization on the individual GEL fibrils. Moiré images were observed in a highly cross-linked HAp/GEL nanocomposite sample and we think the cross-linkage induced the assembly of unordered individual fibrils along the preferential direction.
authors.affiliation: MDRCBB, School of Dentistry, University of Minnesota, 16-280 Moos Tower, 515 Delaware S.E., Minneapolis, MN 55455-0329, USA. mcchang@kusan.ac.kr
authors.forename: Myung Chul
authors.initials: MC
authors.lastname: Chang
authors.forename: Ching Chang
authors.initials: CC
authors.lastname: Ko
authors.forename: William H
authors.initials: WH
authors.lastname: Douglas
mesh_terms: D018786:Bone Substitutes / Q000138:chemical synthesis / Q000737:chemistry*; D017886:Durapatite / Q000138:chemical synthesis / Q000737:chemistry*; D005780:Gelatin / Q000138:chemical synthesis / Q000737:chemistry*; D005976:Glutaral / Q000737:chemistry*; D008420:Manufactured Materials; D008422:Materials Testing; D008968:Molecular Conformation; D036103:Nanotechnology / Q000379:methods*; D013499:Surface Properties
chemical_list: D018786:Bone Substitutes; D005780:Gelatin; D017886:Durapatite; D005976:Glutaral