Lymphangioleiomyomatosis and SZ alpha(1)-antitrypsin disease: a unique combination?
We describe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ alpha(1)-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of such combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.
Chan
Andrew L
AL
University of California, Davis Medical Center, Sacramento, CA, USA. alchan@ucdavis.edu
Kwack
Sunye
S
Jones
Kirk D
KD
Glassberg
Marilyn K
MK
Gherman
Charles R
CR
D000328:Adult; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D018192:Lymphangioleiomyomatosis / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012129:Respiratory Function Tests; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications*