title: [Genome-wide scanning for susceptibility genes in researches on six HLA-associated diseases].
abstract: Six human leucocytic antigen(HLA)-associated diseases, including ankylosing spondylitis, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, type 1 diabetes mellitus and psoriasis, were selected as objects of this review. The characteristics of these diseases in whole-genome scans on susceptibility genes or loci undertaken to date were analyzed and compared. Meanwhile, the potential proposals for dealing with the existing problems were put forward.
authors.affiliation: Department of Medical Genetics, Shanghai Second Medical University, Shanghai, 200025 PR China. mingmingu@hotmail.com
authors.forename: Ming-min
authors.initials: MM
authors.lastname: Gu
authors.forename: Zhu-gang
authors.initials: ZG
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Li-an
authors.initials: LA
authors.lastname: Fan
mesh_terms: D001172:Arthritis, Rheumatoid / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D055106:Genome-Wide Association Study / Q000379:methods*; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics; D011565:Psoriasis / Q000235:genetics; D013167:Spondylitis, Ankylosing / Q000235:genetics
chemical_list: D006680:HLA Antigens