Enzymes of the thiol-dependent hydroperoxide metabolism in pathogens as potential drug targets.
Budde
Heike
H
Department of Biochemistry, Technical University of Braunschweig, Mascheroder Weg 1, D-38124 Braunschweig, Germany.
Flohé
Leopold
L
D000818:Animals; D000900:Anti-Bacterial Agents; D000975:Antioxidants; D000977:Antiparasitic Agents; D001419:Bacteria / Q000201:enzymology*; D002374:Catalase / Q000378:metabolism; D015195:Drug Design; D005979:Glutathione Peroxidase / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000378:metabolism*; D010271:Parasites / Q000201:enzymology*; D013438:Sulfhydryl Compounds / Q000494:pharmacology*; D013481:Superoxides / Q000378:metabolism; D014345:Trypanosoma / Q000201:enzymology
D000900:Anti-Bacterial Agents; D000975:Antioxidants; D000977:Antiparasitic Agents; D013438:Sulfhydryl Compounds; D013481:Superoxides; D006861:Hydrogen Peroxide; D002374:Catalase; D005979:Glutathione Peroxidase