Low-dose warfarin prevents recurrent thromboembolism.
Low-intensity warfarin (target international normalized ratio [INR], 1.5-2.0) effectively prevents recurrent venous thromboembolism without increasing the risk of major bleeding when used long-term for secondary prophylaxis. This is a reasonable approach following at least 3 to 12 months of full-intensity warfarin after the initial thromboembolic event.
Plum
Mary-Beth Fennell
MB
Department of Pharmacy, School of Pharmacy, Virginia Commonwealth University, Richmond, USA. mplum@vcu.edu