title: [Papanicolaou test in pregnancy].
abstract: OBJECTIVE
  To investigate the necessity, safety and acceptability of routine Papanicolaou (Pap) smear in pregnant women and cytological characteristics of the smears during pregnancy.
  
  
  METHODS
  Pap smear were performed in 954 pregnant women, 1,053 normal controls and 1,908 gynecological out-patients. The cytological preparations were analyzed by using PAPNET method and following Bethesda (TBS-NCI) diagnostic criteria. Quality control was carried out by following TBS-NCI standard.
  
  
  RESULTS
  Abnormal epithelial change was found in 89 women (89/954, 9.3%) of pregnant group, which was quite similar to normal controls group and gynecological group. Occurrence rate of cervical squamous intraepithelial lesion (SIL) was the lowest in pregnant group (0.94%, 9 in 954 cases), comparing with control group (2.75%) and gynecological group (6.23%). However, pregnant group had the highest infection rate (89.9%), as compared to gynecological group (64.5%), and normal controls group (69.1%) (P < 0.01).
  
  
  CONCLUSIONS
  Cervical Pap smear test is necessary, safety and acceptable for routine prenatal tests. Any pregnant women with infections must be treated as nonpregnant one.
authors.affiliation: Department of Obstetries and Gynecology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China. chengxm@cssc.pumch.ac.cn
authors.forename: X
authors.initials: X
authors.lastname: Cheng
authors.forename: X
authors.initials: X
authors.lastname: Bian
authors.forename: J
authors.initials: J
authors.lastname: Lang
authors.forename: M
authors.initials: M
authors.lastname: Gai
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: M
authors.initials: M
authors.lastname: Liu
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D065006:Papanicolaou Test; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000453:epidemiology; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000453:epidemiology; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000453:epidemiology; D014626:Vaginal Smears / Q000592:standards*