title: [Regional features of sensitization of children to some noninfectious allergens].
abstract: The results of epidemiological investigations within the frames of the ISAAC program are presented. Out of 2,870 children, 172 children (6.0%) with sensitization to some noninfectious (insect, pollen, medicinal) allergens were detected. The number of allergic children was found to be 10.4 +/- 1.8 to 28.2 +/- 3.0 per 1000 of urban child population. Specific features of the sensitization of urban children to regional insect, pollen and medicinal allergens were established. The clinical course of allergic diseases in children was characterized by polymorphism and a great variety of clinical symptoms with frequent lesions of the gastrointestinal tract and functional disturbances of the central nervous system, which adversely affected the school studies of children and the quality of their life. In the development of allergy in children such factors of risk as hereditary predisposition to allergy, allergic diathesis, focal infections and artificial feeding during the first year of life were also of great importance.
authors.affiliation: Pediatric Medical Institute, Tashkent, Uzbekistan, Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
authors.forename: I R
authors.initials: IR
authors.lastname: Iuldashev
authors.forename: V M
authors.initials: VM
authors.lastname: Berzhets
authors.forename: O I
authors.initials: OI
authors.lastname: Iusupova
authors.forename: K Sh
authors.initials: KSh
authors.lastname: Doniiarov
authors.forename: G T
authors.initials: GT
authors.lastname: Isabaeva
mesh_terms: D000485:Allergens / Q000009:adverse effects* / Q000276:immunology; D000818:Animals; D002648:Child; D004198:Disease Susceptibility / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000209:etiology* / Q000276:immunology; D007313:Insecta / Q000276:immunology; D011058:Pollen / Q000276:immunology; D011788:Quality of Life; D012307:Risk Factors; D014505:Urban Population / Q000706:statistics & numerical data; D014610:Uzbekistan / Q000453:epidemiology
chemical_list: D000485:Allergens