Microchip electrophoresis for chiral separations.
Microchip electrophoresis (MCE) is a promising new technique for the separation of enantiomers. This recently introduced technique enables chiral separations to be performed in seconds on tiny micromachined devices. This review is intended to give a brief introduction into the principles of chiral separations with MCE with regard to methodology and instrumentation. Different approaches to realize chiral separations in microfluidic devices are described and discussed. This review gives an overview of original work done in this field with emphasis on approaches to improve detection and resolution in chiral MCE.
Belder
Detlev
D
Abteilung für Chromatographie, Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim an der Ruhr, Germany. belder@mpi-mulheim.mpg.de
Ludwig
Martin
M
D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods*; D008832:Microchemistry / Q000295:instrumentation*; D004364:Pharmaceutical Preparations / Q000302:isolation & purification; D013237:Stereoisomerism
D004364:Pharmaceutical Preparations