Tubulointerstitial dysfunction in early post-transplant period.
Dysfunction of a transplanted kidney may develop at any time in the post-transplant period. The aim of this study was to differentiate levels of early dysfunction of a transplanted kidney. The study included 45 examinees undergoing kidney transplantation. They were divided into four groups, in regard to length of hospitalization and post-transplant complications: group I (up to 15 days, complication-free); group II (up to 15 days, with complications); group III (up to 30 days); group IV (up to 60 days). The control group included patients undergoing abdominal surgery, without uropoetic system disorders. The following parameters were examined on a daily basis a month after transplantation on average: creatinine clearance, creatinine and urea. Statistical analysis of these parameters revealed the following levels of renal dysfunction: control group--circulatory tubular dysfunction without azotemia; group I--polyuric acute tubular necrosis; group II and group III--severe or moderately severe polyuric acute tubular necrosis and group IV--polyuric acute tubular necrosis.
Durdević-Mirković
Tatjana
T
Institut za interne bolesti Klinika za nefrologiju i klinicku imunologiju, Klinicki centar Novi Sad. milanam@teamnet.ws
Curić
Slobodan
S
Vodopivec
Slavenka
S
Sedlak-Vadoc
Valerija
V
Stosić
Zoran
Z
Mitić
Igor
I
Bozić
Dusan
D
Petrović
Lada
L
Ilić
Tatjana
T
D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology* / Q000503:physiopathology; D007684:Kidney Tubules / Q000503:physiopathology*