Relation between recurrent vulvovaginal candidiasis, vaginal concentrations of mannose-binding lectin, and a mannose-binding lectin gene polymorphism in Latvian women.
Vaginal concentrations of mannose-binding lectin (MBL) and possession of a polymorphism in codon 54 of the MBL gene were determined in 42 women with recurrent vulvovaginal candidiasis (RVVC) and 43 control subjects. Reduced vaginal MBL levels and an increased occurrence of the polymorphism were present in women with RVVC.
Babula
Oksana
O
Department of Obstetric and Gynecology, Weill Medical College of Cornell University, New York, NY 10021, USA.
Lazdane
Gunta
G
Kroica
Juta
J
Ledger
William J
WJ
Witkin
Steven S
SS
D000293:Adolescent; D000328:Adult; D002176:Candida albicans / Q000187:drug effects / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism*; D003062:Codon / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007844:Latvia / Q000453:epidemiology; D037601:Mannose-Binding Lectin / Q000235:genetics* / Q000378:metabolism*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012008:Recurrence
D003062:Codon; D037601:Mannose-Binding Lectin