title: Cytogenetic effects of antibodies to gamma-interferon in ultralow doses.
abstract: Single and course administration of ultralow doses of antibodies gamma-interferon did not increase the incidence of cytogenetic abnormalities in bone marrow cells from BALB/c mice and produced no genotoxic effect on Drosophila melanogaster wing cells in the test of somatic mosaicism.
authors.affiliation: Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
authors.forename: O L
authors.initials: OL
authors.lastname: Voronova
authors.forename: O P
authors.initials: OP
authors.lastname: Rogozina
authors.forename: A V
authors.initials: AV
authors.lastname: Martyushev
authors.forename: S A
authors.initials: SA
authors.lastname: Sergeeva
authors.forename: O I
authors.initials: OI
authors.lastname: Epstein
authors.forename: A M
authors.initials: AM
authors.lastname: Dygai
authors.forename: E D
authors.initials: ED
authors.lastname: Goldberg
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000633:toxicity*; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004331:Drosophila melanogaster / Q000187:drug effects*; D007371:Interferon-gamma / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D014921:Wings, Animal / Q000166:cytology / Q000187:drug effects
chemical_list: D000906:Antibodies; D009153:Mutagens; D007371:Interferon-gamma