title: Conformational analysis by HRMAS NMR spectroscopy of resin-bound homo-peptides from C(alpha)-methyl-leucine.
abstract: A series of [L-(alphaMe)Leu]n (n = 1-5) homo-peptides have been covalently linked to Tentagel and POEPOP resins and submitted to a conformational study using HRMAS NMR spectroscopy. Whereas the mono- and dipeptide are mainly fully-extended, stable 3(10)-helical structures are formed beginning from the trimer.
authors.affiliation: Institute of Biomolecular Chemistry, CNR, Department of Organic Chemistry, University of Padova, 35131 Padova, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Rainaldi
authors.forename: Nathalie
authors.initials: N
authors.lastname: Lancelot
authors.forename: Karim
authors.initials: K
authors.lastname: Elbayed
authors.forename: Jesus
authors.initials: J
authors.lastname: Raya
authors.forename: Martial
authors.initials: M
authors.lastname: Piotto
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Briand
authors.forename: Bernard
authors.initials: B
authors.lastname: Kaptein
authors.forename: Quirinus B
authors.initials: QB
authors.lastname: Broxterman
authors.forename: Albrecht
authors.initials: A
authors.lastname: Berkessel
authors.forename: Fernando
authors.initials: F
authors.lastname: Formaggio
authors.forename: Claudio
authors.initials: C
authors.lastname: Toniolo
authors.forename: Alberto
authors.initials: A
authors.lastname: Bianco
mesh_terms: D007930:Leucine / Q000031:analogs & derivatives*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D009842:Oligopeptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D012117:Resins, Synthetic
chemical_list: D009842:Oligopeptides; D012117:Resins, Synthetic; D007930:Leucine