[Neuroendocrine differentiation of bladder tumors].
Neuroendocrine bladder tumours (NET) constitute a group of various tumours with a common neuroendocrine phenotype. This is a very well defined entity (morphological, immunohistochemical, and ultrastructural). The great majority of bladder NETs reported in the literature are high-grade small cell carcinomas, but large cell carcinoma are probably underestimated due to the lack of systematic investigation. This paper reviews these rare, poorly known tumours, which require specific management. All bladder NETs are described. The frequency and diagnostic and therapeutic strategy of neuroendocrine bladder tumours are described.
Vincendeau
Sébastien
S
Service d'Urologie, Hôpital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes. vincendeausebas@yahoo.fr
de Lajarte-Thirouard
Anne-Sophie
AS
Bensalah
Karim
K
Guillé
François
F
Lobel
Bernard
B
Patard
Jean-Jacques
JJ
D006801:Humans; D018358:Neuroendocrine Tumors; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy