title: Synthesis and cytotoxic evaluation of novel thiazolocarbazoles. Part III.
abstract: Novel thiazolocarbazole derivatives have been synthesized via the corresponding imino-1,2,3-dithiazoles. In vitro antitumor activity of these polyheterocyclic compounds was studied.
authors.affiliation: Laboratoire de Génie Protéique et Cellulaire, EA3169, Groupe de Chimie Organique, UFR Sciences Fondamentales et Sciences pour l'Ingénieur, Bâtiment Marie Curie, Université, de la Rochelle, F-17042 La Rochelle cedex 1, France.
authors.forename: Hadjila
authors.initials: H
authors.lastname: Chabane
authors.forename: Christelle
authors.initials: C
authors.lastname: Lamazzi
authors.forename: Valerie
authors.initials: V
authors.lastname: Thiery
authors.forename: Alain
authors.initials: A
authors.lastname: Pierre
authors.forename: Stephane
authors.initials: S
authors.lastname: Leonce
authors.forename: Bruno
authors.initials: B
authors.lastname: Pfeiffer
authors.forename: Pierre
authors.initials: P
authors.lastname: Renard
authors.forename: Gérald
authors.initials: G
authors.lastname: Guillaumet
authors.forename: Thierry
authors.initials: T
authors.lastname: Besson
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002227:Carbazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D020128:Inhibitory Concentration 50; D007939:Leukemia L1210 / Q000473:pathology; D051379:Mice; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D002227:Carbazoles; D013844:Thiazoles