title: [Adverse effects of concomitant chemoradiotherapy and their prevention and treatment].
abstract: Concomitant chemoradiotherapy plays an important role in the treatment of malignancies. Concomitant chemoradiotherapy improves the local control and overall survival compare to separate treatment modalities. Combined treatment leads to higher toxicity. Most frequent side effects during concomitant chemoradiotherapy are diarrhoea, mucositis, skin reactions and haematologic toxicity. Optimal combination of treatment modalities, fractionation and dosage of radiotherapy, modern planning techniques and use of radioprotective drugs could decrease the treatment toxicity.
authors.affiliation: Klinika komplexní onkologické péce-oddĕlení radiacní onkologie, Masarykův onkologický ústav, Brno. horova@mou.cz
authors.forename: H
authors.initials: H
authors.lastname: Horová
authors.forename: R
authors.initials: R
authors.lastname: Soumarová
authors.forename: Z
authors.initials: Z
authors.lastname: Seneklová
authors.forename: J
authors.initials: J
authors.lastname: Růzicková
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D003131:Combined Modality Therapy / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents