title: Histopathologically proven poliomyelitis with quadriplegia and loss of brainstem function due to West Nile virus infection.
abstract: Recent electrophysiological and histopathological reports point to motor neurons in the anterior horn of the spinal cord and the brainstem as targets of severe West Nile virus (WNV) infection. We report histopathological confirmation of this poliomyelitis-like syndrome in a patient with WNV infection in Massachusetts.
authors.affiliation: Department of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Boston, MA, USA. sdoron@tufts-nemc.org
authors.forename: Shira I
authors.initials: SI
authors.lastname: Doron
authors.forename: John F
authors.initials: JF
authors.lastname: Dashe
authors.forename: Lester S
authors.initials: LS
authors.lastname: Adelman
authors.forename: William F
authors.initials: WF
authors.lastname: Brown
authors.forename: Barbara G
authors.initials: BG
authors.lastname: Werner
authors.forename: Susan
authors.initials: S
authors.lastname: Hadley
mesh_terms: D000368:Aged; D001933:Brain Stem / Q000503:physiopathology* / Q000821:virology*; D006801:Humans; D008297:Male; D011051:Poliomyelitis / Q000821:virology*; D011782:Quadriplegia / Q000821:virology*; D014901:West Nile Fever / Q000821:virology*; D014902:West Nile virus / Q000302:isolation & purification