title: A retrospective hospital-based study on congenital hypothyroidism in the Sultanate of Oman.
abstract: A retrospective study was conducted on 45 children with congenital hypothyroidism (CH) to estimate the number of missed cases of CH among Omani children per year and compare the intellectual outcome of children diagnosed by neonatal screening (Group A) with those who were diagnosed clinically at a later age (Group B). Our results revealed 14 children in Group A, diagnosed at a mean age of 2.3 +/- 0.8 months and 31 children in Group B diagnosed at a mean age of 9.8 +/- 2.5 months. IQ assessment revealed that 67 per cent of the children in Group A had a normal IQ compared to only 15 per cent of those in Group B. The above results point to a great demand for a national screening programme in the Sultanate of Oman.
authors.affiliation: Paediatric Endocrinology and Metabolic Unit, Royal Hospital, Sultanate of Oman. alqubtan@yahoo.com
authors.forename: H A
authors.initials: HA
authors.lastname: Al Shaikh
authors.forename: B
authors.initials: B
authors.lastname: Bappal
authors.forename: R
authors.initials: R
authors.lastname: Nair
authors.forename: S
authors.initials: S
authors.lastname: Al Khusaiby
mesh_terms: D003409:Congenital Hypothyroidism; D005260:Female; D006761:Hospitals; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000000981:diagnostic imaging; D007223:Infant; D008607:Intellectual Disability / Q000209:etiology / Q000517:prevention & control; D008297:Male; D008403:Mass Screening; D009850:Oman; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013667:Technetium; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013667:Technetium; D013972:Thyrotropin; D013974:Thyroxine