[Matrix effects in inductively coupled plasma mass spectrometry by use of organic solvents].
Matrix effects arising from ethanol, propanol, glycerol, acetic acid, ethylenediamine and triethanolamine in inductively coupled plasma mass spectrometry have been studied. Addition of ethanol, propanol, glycerol, acetic acid, ethylenediamine and triethanolamine into solution has an enhancement effect on the signal intensity of analyte with ionization potential between 9 and 11 eV. The ethylenediamine and triethanolamine have higher enhancement effect on the signal intensity of Hg than that of ethanol, propanol, glycerol and acetic acid. Addition of ethylenediamine and triethanolamine into solution has a suppression effect on the signal intensity of Pb and Sr. The mechanism of the enhancement or suppression was investigated. The signal enhancement of Hg in the presence of ethylenediamine and triethanolamine is not caused by improved degree of ionization of Hg and nebulization efficiency. The suppression effects of Pb and Sr in the presence of ethylenediamine and triethanolamine are due to decrease of atomization efficiency of these elements. A method for the determination of Hg in the biological standard samples by ICP-MS was developed.
Cao
S
S
Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, National Electrochemistry and Spectroscopy Research Analysis Center, 130022 Changchun.
Chen
H
H
Zeng
X
X
D000433:1-Propanol; D001151:Arsenic / Q000032:analysis*; D000431:Ethanol; D004983:Ethanolamines; D005029:Ethylenediamines; D005990:Glycerol; D007202:Indicators and Reagents; D007854:Lead / Q000032:analysis; D013058:Mass Spectrometry / Q000379:methods; D008628:Mercury / Q000032:analysis*; D012997:Solvents
D004983:Ethanolamines; D005029:Ethylenediamines; D007202:Indicators and Reagents; D012997:Solvents; D007854:Lead; D000431:Ethanol; C031234:ethylenediamine; D000433:1-Propanol; C009546:triethanolamine; D008628:Mercury; D001151:Arsenic; D005990:Glycerol