Synthesis of the aminocyclopentitol moieties of the hopanoids of Zymomonas mobilis and 'Anacystis montana'.
The first synthesis of the cyclopentitol units in bacterial hopanoids has been accomplished from D-glucosamine and the possible biological activity of the free cyclitols as glycosidase inhibitors has been studied.
Chiara
Jose Luis
JL
Instituto de Química Orgánica General, CSIC, Juan de la Cierva, 3. Madrid, Spain. jl.chiara@iqog.csic.es
Storch de Gracia
Isabel
I
Bastida
Agatha
A
D000605:Amino Alcohols / Q000138:chemical synthesis* / Q000494:pharmacology; D000458:Cyanobacteria / Q000737:chemistry*; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D005959:Glucosidases / Q000037:antagonists & inhibitors; D007700:Kinetics; D008956:Models, Chemical; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry*; D017355:Zymomonas / Q000737:chemistry*
D000605:Amino Alcohols; D003517:Cyclopentanes; D004791:Enzyme Inhibitors; D014315:Triterpenes; D005959:Glucosidases