Facile syntheses of the hexasaccharide repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A.
Two hexasaccharides, beta-D-Xylp-(1-->2)-alpha-D-Manp-(1-->3)-[beta-D-Xylp-(1-->2)-]alpha-D-Manp-(1-->3)-[beta-D-GlcpA-(1-->2)-]alpha-D-Manp and beta-D-GlcpA-(1-->2)-alpha-D-Manp-(1-->3)-[beta-D-Xylp-(1-->2)-]alpha-D-Manp-(1-->3)-[beta-D-Xylp-(1-->2)-]alpha-D-Manp, the repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A, were synthesized as their methyl glycosides in a regio- and stereoselective manner.
Zhang
Jianjun
J
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Kong
Fanzuo
F
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D003455:Cryptococcus neoformans / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry; D006027:Glycosides / Q000138:chemical synthesis*; D008358:Mannose / Q000737:chemistry; D008969:Molecular Sequence Data; D019081:O Antigens / Q000737:chemistry; D009844:Oligosaccharides / Q000138:chemical synthesis*; D011135:Polysaccharides, Bacterial / Q000737:chemistry* / Q000302:isolation & purification; D012703:Serotyping; D013329:Structure-Activity Relationship; D014994:Xylose / Q000737:chemistry
D006027:Glycosides; D019081:O Antigens; D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial; D014994:Xylose; D005947:Glucose; D008358:Mannose