title: A very rare localization of metastatic lung carcinoma to the interosseous membrane.
abstract: BACKGROUND
  Soft tissue is a rare localization of carcinoma metastasis. Skeletal muscle is considered the most frequent site. The aim of this paper is to report a very rare localization of soft-tissue metastasis of lung adenocarcinoma in the lower leg interosseous membrane, surgically treated at our department.
  
  
  METHODS
  A 66-year-old man with a history of lung adenocarcinoma was admitted to our department because he complained of a pain resistant to drugs that had persisted for 1 month. Imaging showed that the lesion was unique, localized in the interosseous membrane, with a distal margin more than 2 cm above the ankle platform. A distal fibula resection, including the tumour and a reconstruction according to Capanna type A2 was performed.
  
  
  RESULTS
  At the 6 months follow-up, the patient was walking without external support.
  
  
  CONCLUSIONS
  Surgery is not the treatment of choice for soft-tissue metastases, but it may be recommended when the lesion is unique and inducing a pain resistant to anti-inflammatory drugs.
authors.affiliation: Department of Orthopaedics, Catholic University, Rome, Italy. Giuliomac@tiscali.it
authors.forename: G
authors.initials: G
authors.lastname: Maccauro
authors.forename: F
authors.initials: F
authors.lastname: Liuzza
authors.forename: F
authors.initials: F
authors.lastname: Muratori
authors.forename: G
authors.initials: G
authors.lastname: Falcone
authors.forename: G
authors.initials: G
authors.lastname: Gosheger
authors.forename: G
authors.initials: G
authors.lastname: Gosegher
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary*; D005360:Fibula / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D019637:Orthopedic Procedures / Q000379:methods; D016896:Treatment Outcome