title: Enantioselective Synthesis of L-CCG-I.
abstract: Introduction of natural menthol as the chiral auxiliary in a gamma-Br-alpha,beta-unsaturated ester leads to enantioselective generation of three chiral centers in a single step on reaction with a glycine anion equivalent to provide L-CCG-I in 94% ee.
authors.affiliation: Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune 411008, India. spchavan@dalton.ncl.res.in
authors.forename: Subhash P
authors.initials: SP
authors.lastname: Chavan
authors.forename: Pallavi
authors.initials: P
authors.lastname: Sharma
authors.forename: Rasapalli
authors.initials: R
authors.lastname: Sivappa
authors.forename: Mohan M
authors.initials: MM
authors.lastname: Bhadbhade
authors.forename: Rajesh G
authors.initials: RG
authors.lastname: Gonnade
authors.forename: Uttam R
authors.initials: UR
authors.lastname: Kalkote
mesh_terms: D000600:Amino Acids, Dicarboxylic / Q000138:chemical synthesis* / Q000737:chemistry; D005998:Glycine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D007536:Isomerism; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: D000600:Amino Acids, Dicarboxylic; D007202:Indicators and Reagents; C035261:(alpha-carboxycyclopropyl)glycine; D005998:Glycine