Effect of long-term hypokinesia on monoamine system and antioxidant status of the brain.
Long-term hypokinesia (30 days) was accompanied by activation of the serotoninergic and dopaminergic systems. Exhaustion of the antioxidant system was observed on days 10-30 of immobilization.
Kamskova
Yu G
YG
Chelyabinsk State Training University, Moscow.
Pavlova
V I
VI
Popkova
E V
EV
Loktionova
I V
IV
Arkhipenko
Yu V
YV
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D002374:Catalase / Q000378:metabolism; D002570:Ceruloplasmin / Q000032:analysis; D004298:Dopamine / Q000032:analysis*; D005260:Female; D018476:Hypokinesia / Q000378:metabolism*; D015227:Lipid Peroxidation; D008297:Male; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000032:analysis*; D013315:Stress, Psychological; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors
D000975:Antioxidants; D012701:Serotonin; D002374:Catalase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin; D004298:Dopamine; D009638:Norepinephrine