title: Synthesis of enantiopure axially chiral C3-symmetric tripodal ligands and their application as catalysts in the asymmetric addition of dialkylzinc to aldehydes.
abstract: The enantioselective synthesis of a novel-type C(3)-symmetric tripodal ligand that is composed of a central mesitylene-derived core and three functionalized, axially chiral biaryl subunits is described. The triol (M,M,M)-3 is a suitable catalyst for the enantioselective addition of dialkylzinc to various aromatic aldehydes with asymmetric inductions of up to 98% ee.
authors.affiliation: Institut für Organische Chemie, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany. bringman@chemie.uni-wuerzburg.de
authors.forename: Gerhard
authors.initials: G
authors.lastname: Bringmann
authors.forename: Robert-Michael
authors.initials: RM
authors.lastname: Pfeifer
authors.forename: Christian
authors.initials: C
authors.lastname: Rummey
authors.forename: Kristina
authors.initials: K
authors.lastname: Hartner
authors.forename: Matthias
authors.initials: M
authors.lastname: Breuning