A conformationally flexible tetrahydroxycalix[4]arene adopting the unusual 1,3-alternate conformation.
The use of a chiral solvating agent enabled the determination of the NMR-silent ring-inversion process of the ketocalixarene 3. Spectroscopic and crystal data indicate that 3 adopts the unusual 1,3-alternate conformation.
Seri
Noa
N
Department of Organic Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Simaan
Samah
S
Botoshansky
Mark
M
Kaftory
Menahem
M
Biali
Silvio E
SE