[Dendritic cells and their role in inflammation in the central nervous system].
Dendritic cells play a key role in initiation and regulation of adaptive immunity against pathogens and tumors, as well as in autoimmune disease. In this article we review recent data regarding distribution of dendritic cells in the central nervous system, their role in responses and possible role in pathogenesis of multiple sclerosis. We also consider possibilities to use dendritic cells as immunotherapeutic targets in multiple sclerosis.
Pashchenkov
M V
MV
Pinegin
B V
BV
Link
Kh
Kh
Boĭko
A N
AN
D001692:Biological Transport / Q000502:physiology; D015704:CD4 Antigens / Q000276:immunology; D002465:Cell Movement / Q000502:physiology; D002490:Central Nervous System / Q000276:immunology* / Q000473:pathology*; D016207:Cytokines / Q000276:immunology; D003712:Dendrites / Q000276:immunology / Q000473:pathology / Q000502:physiology*; D006684:HLA-DR Antigens / Q000276:immunology; D059810:HLA-DR Serological Subtypes; D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology* / Q000473:pathology*; D013601:T-Lymphocytes / Q000502:physiology
D015704:CD4 Antigens; D016207:Cytokines; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C106559:HLA-DR15 antigen