title: In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of former prisoners of war with and without posttraumatic stress disorder.
abstract: Proton magnetic resonance spectroscopy was used to compare medial temporal lobe (MTL) concentrations of N-acetylaspartate and choline between former prisoners of war (POWs) with and without posttraumatic stress disorder (PTSD). MTL N-acetylaspartate and reexperiencing symptoms correlated strongly in the POW subjects with PTSD, suggesting a relationship between reexperiencing symptoms and the integrity of MTL structures.
authors.affiliation: Mental Health Service, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.
authors.forename: Shelley
authors.initials: S
authors.lastname: Brown
authors.forename: Thomas
authors.initials: T
authors.lastname: Freeman
authors.forename: Tim
authors.initials: T
authors.lastname: Kimbrell
authors.forename: David
authors.initials: D
authors.lastname: Cardwell
authors.forename: Richard
authors.initials: R
authors.lastname: Komoroski
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D003401:Creatine / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011329:Prisoners; D011522:Protons; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013313:Stress Disorders, Post-Traumatic / Q000378:metabolism / Q000473:pathology*; D013702:Temporal Lobe / Q000378:metabolism / Q000473:pathology*; D014728:Veterans; D014857:Warfare
chemical_list: D011522:Protons; D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline