title: [Biologic function of p21WAF1/CIP1 gene and its association with carcinogenesis].
abstract: p21WAF1/CIP1 gene is known for a most important cell cycle regulator as well as its roles in appoptosis and differentiation. This review focuses on p21WAF1/CIP1 gene functions and its association with carcinogenesis. Better understanding of the structure and function of p21WAF1/CIP1 gene may help to comprehend molecular mechanisms of cancers and to facilitate diagnosis and treatment of malignancy.
authors.affiliation: Peking University School of Oncology, Department of Genetic, Beijing Institute for Cancer Research, Beijing 100034, China.
authors.forename: Yaguang
authors.initials: Y
authors.lastname: Xi
authors.forename: Yinghui
authors.initials: Y
authors.lastname: Ren
authors.forename: Xiulan
authors.initials: X
authors.lastname: Su
authors.forename: Yang
authors.initials: Y
authors.lastname: Ke
mesh_terms: D063646:Carcinogenesis; D002454:Cell Differentiation; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000235:genetics*; D006801:Humans
chemical_list: C493956:CDKN1A protein, human; D050759:Cyclin-Dependent Kinase Inhibitor p21