Adenocarcinoma in situ arising from the submucosal oesophageal mucous glands.
The incidence of adenocarcinoma of the oesophagus is increasing; this type of carcinoma commonly arises on Barrett's oesophagus. We report a case of in-situ adenocarcinoma of the lower oesophagus arising in submucosal oesophageal mucous glands without intestinal metaplasia. We describe the histological findings, discuss the difficulties of differentiating this from invasive disease and review the current literature regarding this rare condition.
Fabre
Aurélie
A
Department of Histopathology, St Mary's Hospital, Imperial School of Medicine, London, UK.
Tansey
Donall K
DK
Dave
Umakant
U
Wright
Mark
M
Teare
Julian P
JP
Rosin
David R
DR
Thompson
Mary E
ME
D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology*; D003937:Diagnosis, Differential; D004938:Esophageal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness