Effects of peptides on proliferative activity of retinal and pigmented epithelial cells.
We studied the effects of Retinalamin (polypeptide preparation isolated from the retina) and a synthetic peptide Epithalon (Ala-Glu-Asp-Gly) on proliferative activity of retinal and pigmented epithelial cells. Experiments showed that Retinalamin and Epithalon (in certain concentrations) tissue-specifically stimulated proliferation of retinal and pigmented epithelial cell in culture.
Khavinson
V Kh
VKh
St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of Russian Academy of Medical Sciences, Moscow. ibg4@medport.ru
Zemchikhina
V N
VN
Trofimova
S V
SV
Malinin
V V
VV
D000818:Animals; D002455:Cell Division / Q000502:physiology*; D002478:Cells, Cultured; D046508:Culture Techniques; D006801:Humans; D009842:Oligopeptides / Q000378:metabolism*; D010857:Pigment Epithelium of Eye / Q000166:cytology / Q000502:physiology*; D051381:Rats; D012160:Retina / Q000737:chemistry* / Q000166:cytology / Q000502:physiology*
D009842:Oligopeptides; C421253:alanyl-glutamyl-aspartyl-glycine