title: Outbreak of Mycobacterium abscessus infection after soft tissue augmentation.
abstract: BACKGROUND
  Illicit soft-tissue augmentation performed in New York City resulted in an outbreak of Mycobacterium abscessus infection in 2002.
  
  
  OBJECTIVE
  To report two cases of women who developed tender, subcutaneous nodules of the face and buttocks after illicit soft-tissue augmentation with a hyaluronic acid derivative.
  
  
  METHODS
  Two case reports are presented, and the literature is reviewed.
  
  
  RESULTS
  Empiric treatment with clarithromycin (for M. abscessus infection) and prednisone (for foreign body reaction) resulted in clearance of lesions.
  
  
  CONCLUSIONS
  Contaminated or impure material used for soft-tissue augmentation can result in a clustered outbreak of infection or foreign body reaction.
authors.affiliation: Department of Dermatology, New York University Medical Center, 560 1st Avenue, H-100, New York, NY 10016, USA. dr_toy@yahoo.com
authors.forename: Brian R
authors.initials: BR
authors.lastname: Toy
authors.forename: Paul Jarrod
authors.initials: PJ
authors.lastname: Frank
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D003357:Cosmetic Techniques / Q000009:adverse effects*; D004196:Disease Outbreaks; D004866:Equipment Contamination; D005260:Female; D005549:Foreign-Body Reaction / Q000188:drug therapy / Q000209:etiology; D005607:Fraud; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives; D007279:Injections, Subcutaneous; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology*; D009519:New York City / Q000453:epidemiology; D011241:Prednisone / Q000627:therapeutic use; D019651:Plastic Surgery Procedures / Q000009:adverse effects
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D006820:Hyaluronic Acid; D017291:Clarithromycin; D011241:Prednisone