title: Adenocarcinoma in situ arising from the submucosal oesophageal mucous glands.
abstract: The incidence of adenocarcinoma of the oesophagus is increasing; this type of carcinoma commonly arises on Barrett's oesophagus. We report a case of in-situ adenocarcinoma of the lower oesophagus arising in submucosal oesophageal mucous glands without intestinal metaplasia. We describe the histological findings, discuss the difficulties of differentiating this from invasive disease and review the current literature regarding this rare condition.
authors.affiliation: Department of Histopathology, St Mary's Hospital, Imperial School of Medicine, London, UK.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Fabre
authors.forename: Donall K
authors.initials: DK
authors.lastname: Tansey
authors.forename: Umakant
authors.initials: U
authors.lastname: Dave
authors.forename: Mark
authors.initials: M
authors.lastname: Wright
authors.forename: Julian P
authors.initials: JP
authors.lastname: Teare
authors.forename: David R
authors.initials: DR
authors.lastname: Rosin
authors.forename: Mary E
authors.initials: ME
authors.lastname: Thompson
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology*; D003937:Diagnosis, Differential; D004938:Esophageal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness