title: Parathyroid carcinoma: difficult management options.
abstract: Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and these tumours are usually hyperfunctional as opposed to other malignant endocrine tumors. Surgery is the only effective treatment while nonsurgical modalities yield poor results. We report a patient, who presented with palpable mass in the neck and severe hypercalcemia. He underwent debulking surgery and received allendronate, calcitonin, dacarbazine followed by in- situ alcohol instillation with some success.
authors.affiliation: Department of Endocrinology, Postgraduate Institute of Medical Education & Research, Chandigarh - 160 012, India.
authors.forename: A
authors.initials: A
authors.lastname: Bhansali
authors.forename: R N
authors.initials: RN
authors.lastname: Kataria
authors.forename: P
authors.initials: P
authors.lastname: Dutta
authors.forename: M M
authors.initials: MM
authors.lastname: Saha
authors.forename: P
authors.initials: P
authors.lastname: Singh
authors.forename: R J
authors.initials: RJ
authors.lastname: Dash
mesh_terms: D000328:Adult; D000438:Alcohols / Q000627:therapeutic use; D019386:Alendronate / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D002116:Calcitonin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003606:Dacarbazine / Q000627:therapeutic use*; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000438:Alcohols; D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D002116:Calcitonin; D019386:Alendronate