title: The "Malaria's Eve" hypothesis and the debate concerning the origin of the human malaria parasite Plasmodium falciparum.
abstract: The debate over whether the human malaria parasite Plasmodium falciparum underwent a recent severe population bottleneck ("Malaria's Eve" hypothesis) has attracted great attention recently. Understanding the genetic diversity and evolutionary history of the parasite has practical implications for developing disease control measures.
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA. xsu@niaid.nih.gov
authors.forename: Xin Zhuan
authors.initials: XZ
authors.lastname: Su
authors.forename: Jianbing
authors.initials: J
authors.lastname: Mu
authors.forename: Deirdre A
authors.initials: DA
authors.lastname: Joy
mesh_terms: D000818:Animals; D005075:Biological Evolution; D017125:Genes, Protozoan; D014644:Genetic Variation; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology; D010961:Plasmodium / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics* / Q000276:immunology