Substrate control of stereoselection in the rhodium(I) catalyzed intramolecular [4 + 2] cycloaddition reaction.
The Rh(I) catalyzed intramolecular [4 + 2] cycloaddition of representative achiral and chiral enedienes has been shown to proceed with excellent levels of stereoselectivity and in high yield under mild reaction conditions. In contrast, the corresponding noncatalyzed cycloadditions for three substrates in the latter category require higher temperatures and exhibit low levels of stereocontrol.
O'Mahony
Donogh J R
DJ
Department of Chemistry, Montana State University, Bozeman, MT 59717, USA.
Belanger
David B
DB
Livinghouse
Tom
T