[Regenerative activity of muscle allografts and thymus status during long-term laser exposure of adrenals and homoplasty region prior to transplantation].
Cross allografting of both gastrocnemius muscles between intact rats and those with the adrenal and right shin preirradiated with a He-Ne laser (632.8 nm, 2.5-3.0 mW/cm2, 10 sessions within 14 days with the cumulative dose being 15-18 J/cm2 per rat). By the time of grafting, the adrenal activity decreased while the activity of thymus decreased. As a result, the allogenic muscle tissue was resorbed in the irradiated rats, particularly, in the right irradiated shin. At the same time, reinnervation of the grafts with a certain amount of survived allogenic muscle tissue was more active in the right irradiated shin as compared to the left intact one. Survival of the donor muscle tissue and its improved reinnervation was observed in a higher proportion of grafts in the intact rats. The allografts from the right preirradiated shin of animals with irradiated adrenal proved to be more viable as compared to the left intact shin.
Buliakova
N V
NV
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Leninskii pr. 33, Moscow, 119071 Russia.
Azarova
V S
VS
D000311:Adrenal Glands / Q000502:physiology / Q000528:radiation effects*; D000818:Animals; D006614:Hindlimb / Q000528:radiation effects; D007834:Lasers; D009119:Muscle Contraction / Q000502:physiology / Q000528:radiation effects; D018482:Muscle, Skeletal / Q000294:innervation / Q000528:radiation effects* / Q000637:transplantation; D011829:Radiation Dosage; D051381:Rats; D012038:Regeneration / Q000502:physiology / Q000528:radiation effects*; D013950:Thymus Gland / Q000502:physiology / Q000528:radiation effects*; D019737:Transplants