Dendritic metalloporphyrins with a distal H-bond donor as mimics of haemoglobin.
We report the synthesis of iron(II) porphyrins functionalised with first- and second-generation dendrons as mimics of haemoglobin. The porphyrin core bears an ethynyl linker pointing towards the centre of the molecule, in an ideal position for the introduction of a series of distal ligands as potential H-bond donors by Pd0-catalysed Sonogashira cross-coupling.
Felber
Beatrice
B
Laboratorium für Organische Chemie, ETH-Hönggerberg, HCI, CH-8093 Zürich, Switzerland.
Calle
Carlos
C
Seiler
Paul
P
Schweiger
Arthur
A
Diederich
François
F
D018360:Crystallography, X-Ray; D006454:Hemoglobins / Q000737:chemistry*; D006860:Hydrogen Bonding; D008665:Metalloporphyrins / Q000138:chemical synthesis / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
D006454:Hemoglobins; D008665:Metalloporphyrins