[Continuous veno-venous hemofiltration in treatment of severe acute pancreatitis].
OBJECTIVE
To observe the efficacy of continuous veno-venous hemofiltration (CVVH) in the treatment of severe acute pancreatitis (SAP).


METHODS
Fifty three patients with SAP were involved, CVVH was performed for at least 24 hours. During CVVH, the patients' conditions and pancreatic enzymes (amylase and lipase) were observed, serum concentration of endotoxin was measured as well.


RESULTS
After CVVH, the symptoms of patients such as tachycardia, respiratory distress, and abdominal pain were remitted. The APACHE II score decreased significantly. Six hours after CVVH, serum concentration of endotoxin was decreased significantly. Fifteen patients died, the mortality rate was 28.3%.


CONCLUSIONS
CVVH could decrease the mortality rate of SAP with multiple organ dysfunction syndrome.
Shen
Qing
Q
Department of Nephrology, The First Hospital, Chongqing Medical University, Chongqing 400016, China.
Gan
Hua
H
Du
Xiao-gang
XG
Li
Zheng-rong
ZR
Chen
Deng-ju
DJ
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood; D004731:Endotoxins / Q000097:blood; D005260:Female; D006440:Hemofiltration; D006801:Humans; D008049:Lipase / Q000097:blood; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000628:therapy*
D004731:Endotoxins; D008049:Lipase; D000681:Amylases