[The relationship of duodenogastric reflux symptoms with the quantity of intragastric bilirubin].
OBJECTIVE
To investigate the relationship of the symptoms of duodenogastric reflux (DGR) with the quantity of intragastric bilirubin.


METHODS
An apparatus (Bilitec 2000) was used for the monitoring of 24-hour intragastric bile in 18 menopause patients with functional dyspepsia (MPFD) accompanied with the symptoms, such as heartburn, epigastric pain, nausea and vomiting.


RESULTS
In most of the time, the symptoms of DGR appeared when intragastric bilirubin could be detected by Bilitec 2000. Furthermore, the severity of symptoms showed good correlation with the amount of bile refluxed into stomach.


CONCLUSIONS
It may be not necessary to monitor 24-hour intragastric bilirubin by using Bilitec 2000 for only diagnosis of DGR. To obtain objective evidences for DGR, the monitoring duration may be decided on the basis of obvious symptoms. This modification would be helpful to enhancing the compliance of patients in clinical trial.
Gu
Sai
S
Department of Gastroenterology, First Hospital, Chongqing Medical University, Chongqing 400016, China.
Tang
Chengwei
C
Liu
Chunlun
C
D001663:Bilirubin / Q000032:analysis*; D004383:Duodenogastric Reflux / Q000378:metabolism*; D005260:Female; D005750:Gastric Juice / Q000737:chemistry*; D006801:Humans; D010349:Patient Compliance; D013997:Time Factors
D001663:Bilirubin