Chronic myelomonocytic leukemia with abnormal bone marrow eosinophils.
Chronic myelomonocytic leukemia with eosinophilia is a recently defined rare entity frequently associated with t(5;12)(q33;p13) translocation. It usually shows a peripheral eosinophil count greater than 1500/microL. However, the literature contains a small subset of cases in which the major manifestation is bone marrow eosinophilia. We report a case similar to that subset and discuss our finding that the immature eosinophils are identical to those seen in acute myelomonocytic leukemia with abnormal bone marrow eosinophils.
Hyde
Jason
J
Department of Pathology, University of Colorado Health Science Center, Denver, CO 80262, USA. jason.hyde@uchsc.edu
Sun
Tsieh
T
D001853:Bone Marrow / Q000473:pathology*; D004802:Eosinophilia / Q000097:blood / Q000150:complications; D004804:Eosinophils / Q000473:pathology*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D015477:Leukemia, Myelomonocytic, Chronic / Q000150:complications / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged