title: PowerFeed operation of simulated moving bed units: changing flow-rates during the switching interval.
abstract: A possible way to improve the separation performance of simulated moving bed (SMB) units is to change the internal and external liquid flow-rates during the switching period. This operation mode, referred to as PowerFeed, is examined in this work through a model analysis. Similar to the Varicol process, which allows for the asynchronous movement of the ports, the PowerFeed process exhibits more degrees of freedom than the classical SMB process and therefore allows more room for optimization. Using an optimization technique based on a genetic algorithm, all three processes have been optimized for a few case studies in order to determine their relative potentials. It is found that PowerFeed and Varicol provide substantially equivalent performances, which are however significantly superior to those of the classical SMB process.
authors.affiliation: Swiss Federal Institute of Technology Zurich, Laboratorium für Technische Chemie/LTC, ETH-Hönggerberg/HCI, CH-8093 Zurich, Switzerland.
authors.forename: Ziyang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Marco
authors.initials: M
authors.lastname: Mazzotti
authors.forename: Massimo
authors.initials: M
authors.lastname: Morbidelli
mesh_terms: D000465:Algorithms; D002845:Chromatography / Q000379:methods*