[Drug of the month. Voriconazole (Vfend)].
Invasive fungal infections are a rare but important cause of morbidity and mortality among patients with severely compromised host defenses. Despite considerable advances in antifungal therapies over the past years, invasive mycoses remain a stubborn and dramatic problem. Voriconazole is a new triazole antifungal agent which confers a relative survival benefit in fluconazole-resistant invasive candidiasis, and in invasive aspergillosis, fusariosis and Scedosporium infections as well.
Piérard
G E
GE
CHU du Sart Tilman, Service de Dermatopathologie.
Arrese
J E
JE
Quatresooz
P
P
Piérard-Franchimont
C
C
D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry / Q000494:pharmacology*; D014230:Triazoles / Q000737:chemistry / Q000494:pharmacology*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole