title: Percutaneous radiofrequency ablation of pulmonary malignancies: combined treatment with brachytherapy.
abstract: OBJECTIVE
  The purpose of this article is to report the clinical experience and technical feasibility of percutaneous radiofrequency ablation in conjunction with brachytherapy, a novel approach in the treatment of lung neoplasms. Data from three patients with lung malignancies illustrate the expanding therapeutic indications of this minimally invasive intervention.
  
  
  CONCLUSIONS
  Percutaneous radiofrequency ablation in conjunction with brachytherapy is a promising minimally invasive combination modality. It may be a treatment option for patients with primary, recurrent, or metastatic malignancies of the lung that are not amenable to surgery or further external beam radiation therapy.
authors.affiliation: Department of Diagnostic Imaging, Rhode Island Hospital, Brown Medical School, 593 Eddy St., Providence, RI 02903, USA.
authors.forename: Sapna K
authors.initials: SK
authors.lastname: Jain
authors.forename: Damian E
authors.initials: DE
authors.lastname: Dupuy
authors.forename: Gene A
authors.initials: GA
authors.lastname: Cardarelli
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zheng
authors.forename: Thomas A
authors.initials: TA
authors.lastname: DiPetrillo
mesh_terms: D000368:Aged; D001918:Brachytherapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000628:therapy*; D002292:Carcinoma, Renal Cell / Q000532:radiotherapy* / Q000556:secondary / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000628:therapy*; D017115:Catheter Ablation; D003131:Combined Modality Therapy; D005240:Feasibility Studies; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000628:therapy*; D008175:Lung Neoplasms / Q000532:radiotherapy* / Q000556:secondary / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D013997:Time Factors; D014057:Tomography, X-Ray Computed