Synthesis and evaluation of N,S-compounds as chiral ligands for transfer hydrogenation of acetophenone.
New nitrogen- and sulfur-containing compounds, bicyclic and monocyclic, were prepared and evaluated as ligands in the transfer hydrogenation of acetophenone. Utilising [Ir(COD)Cl]2 as metal precursor the best result, 80% ee, was obtained using a bicyclic sulfoxide ligand.
Ekegren
Jenny K
JK
Department of Organic Chemistry, Uppsala University, Box 531, SE-751 21 Uppsala, Sweden.
Roth
Peter
P
Källström
Klas
K
Tarnai
Tibor
T
Andersson
Pher G
PG