title: Synthesis of substituted p-stereogenic vinylphosphine oxides by olefin cross-metathesis.
abstract: [reaction: see text] Substituted vinylphosphine oxides have been prepared in good yield and exclusive (E)-olefin selectivity via olefin cross-metathesis using Grubbs and Hoveyda-type ruthenium catalysts. In addition, metathesis of chiral vinylphosphine oxides proceeds without racemization of the phosphorus chirality center, providing easy access to functionalized chiral nonracemic (E)-alkenylphosphine oxides.
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Oleg M
authors.initials: OM
authors.lastname: Demchuk
authors.forename: K Michał
authors.initials: KM
authors.lastname: Pietrusiewicz
authors.forename: Anna
authors.initials: A
authors.lastname: Michrowska
authors.forename: Karol
authors.initials: K
authors.lastname: Grela