title: Fat augmentation for nonparalytic glottic insufficiency.
abstract: While autogenous fat augmentation for glottic insufficiency has been used before, relatively little information is currently available on the effectiveness of fat injection in patients with nonparalytic glottic insufficiency resulting from problems such as various defects of vocal atrophy or sulcus vocalis. This paper compares retrospectively the efficiency of fat injection after surgery in patients with vocal atrophy (n = 16) and sulcus vocalis (n = 8). The perceptual acoustic and phonatory functions and videolaryngostroboscopic data were evaluated before and after fat augmentation in 24 patients. The mean follow-up time was 19.5 months. Fifteen patients displayed excellent results; 1 showed some improvement; 6 experienced postprocedure failure, and 2 were not available for follow-up analysis. Perceptual rating showed significant improvement in grade, roughness and breathiness (p < 0.05). The videolaryngostroboscopic rating showed significant improvements in vocal fold edge linearity, vocal fold vibration amplitude and mucosal wave excursion (p < 0.05). More improvement in vocal atrophy was observed compared with sulcus vocalis following fat injection procedures. Our research showed that middle defects improved more compared to those in the anterior and posterior area. Fat injection is an effective autogenous implant and may be considered as an option in the treatment of patients with vocal atrophy or sulcus vocalis. Although fat reabsorption was a problem, repeating the procedure could be considered.
authors.affiliation: Department of Otolaryngology, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheunggung Road, Sec. 2, Taipei 114, Taiwan, ROC.
authors.forename: Yen-Yu
authors.initials: YY
authors.lastname: Chen
authors.forename: Lu
authors.initials: L
authors.lastname: Pai
authors.forename: Yaoh-Shiang
authors.initials: YS
authors.lastname: Lin
authors.forename: Hsing-Won
authors.initials: HW
authors.lastname: Wang
authors.forename: Ming-Wang
authors.initials: MW
authors.lastname: Hsiung
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D000368:Aged; D001284:Atrophy; D005260:Female; D005931:Glottis / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007267:Injections; D007818:Laryngeal Diseases / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010699:Phonation; D012189:Retrospective Studies; D014827:Vocal Cords / Q000473:pathology / Q000601:surgery*