Magnetic resonance imaging of lymphomatoid granulomatosis: punctate and linear enhancement preceding hemorrhage.
Lymphomatoid granulomatosis (LG) is an angiocentric and angiodestructive lymphoproliferative disease that mainly involves the lung. Thirty percent of patients with LG have neurological symptoms. We report serial changes in MRI of a patient with LG of the brain. Postcontrast MRI demonstrated multiple punctate and linear areas that preceded hemorrhage, as indicated by hypointensity with surrounding hyperintensity on subsequent T2-weighted images. The diagnostic value of these lesions observed with contrast MR images is discussed. We consider that enhancing areas correspond to walls of small vessels affected by LG.
Miura
Hiroyuki
H
Fifth Department of Internal Medicine, Tokyo Medical University, 3-20-1, Chuo, Ami, Inashiki, Ibaraki 300-0395, Japan. hmiura@tokyo-med.ac.jp
Shimamura
Hideki
H
Tsuchiya
Kazuhiro
K
Hatao
Ei-ichi
E
Kusama
Hiroshi
H
Matsuoka
Takeshi
T
D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000150:complications / Q000175:diagnosis; D016399:Lymphoma, T-Cell / Q000175:diagnosis; D008230:Lymphomatoid Granulomatosis / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male