title: Highly enantioselective catalytic asymmetric hydrogenation of beta-keto esters in room temperature ionic liquids.
abstract: Polar phosphonic acid-derived Ru-BINAP systems were used to catalyze asymmetric hydrogenation of beta-keto esters in room temperature ionic liquids (RTILs) with complete conversions and ee values higher than those obtained from homogeneous reactions in MeOH (up to 99.3%), and were recycled by simple extraction and used for four times without the loss of activity and enantioselectivity.
authors.affiliation: Department of Chemistry, CB#3290, University of North Carolina, Chapel Hill, NC 27599, USA.
authors.forename: Helen L
authors.initials: HL
authors.lastname: Ngo
authors.forename: Aiguo
authors.initials: A
authors.lastname: Hu
authors.forename: Wenbin
authors.initials: W
authors.lastname: Lin