Tuning the keto equilibrium in 4-substituted dipicolinic acid derivatives.
The synthesis of 4-substituted dipicolinic acid derivatives requiring palladium catalysis is described. A keto-enol equilibrium has been observed, depending on the nature of the 2,6-position substituents.
Chauvin
Anne-Sophie
AS
Institute of Molecular and Biological Chemistry, Swiss Federal Institute of Technology Lausanne, BCH 1405, CH-1015 Lausanne, Switzerland. anne-sophie.chauvin@epfl.ch
Gras
Sandrine
S
Bünzli
Jean-Claude G
JC