title: [Drug of the month. Voriconazole (Vfend)].
abstract: Invasive fungal infections are a rare but important cause of morbidity and mortality among patients with severely compromised host defenses. Despite considerable advances in antifungal therapies over the past years, invasive mycoses remain a stubborn and dramatic problem. Voriconazole is a new triazole antifungal agent which confers a relative survival benefit in fluconazole-resistant invasive candidiasis, and in invasive aspergillosis, fusariosis and Scedosporium infections as well.
authors.affiliation: CHU du Sart Tilman, Service de Dermatopathologie.
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
authors.forename: J E
authors.initials: JE
authors.lastname: Arrese
authors.forename: P
authors.initials: P
authors.lastname: Quatresooz
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry / Q000494:pharmacology*; D014230:Triazoles / Q000737:chemistry / Q000494:pharmacology*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole