title: Spontaneous regression of congenital melanocytic nevi without evidence of the halo phenomenon.
abstract: Spontaneous regression of a congenital melanocytic nevus is rare and has always been thought to be associated with a halo phenomenon, suggesting that an immunological mechanism is involved in the regression process. We describe herein 2 cases of complete congenital melanocytic nevus regression without the halo phenomenon in 2 Japanese girls. To our knowledge, such a clinical progression has not been previously reported. We will also discuss several different possible mechanisms of regression.
authors.affiliation: Department of Dermatology, Kumamoto University School of Medicine, Kumamoto, Japan. toshiro@kaiju.medic.kumamoto-u.ac.jp
authors.forename: Toshiro
authors.initials: T
authors.lastname: Kageshita
authors.forename: Yuji
authors.initials: Y
authors.lastname: Inoue
authors.forename: Tomomichi
authors.initials: T
authors.lastname: Ono
mesh_terms: D002675:Child, Preschool; D005260:Female; D005385:Fingers; D006801:Humans; D007223:Infant; D009508:Nevus, Pigmented / Q000151:congenital* / Q000473:pathology; D012075:Remission, Spontaneous; D012878:Skin Neoplasms / Q000151:congenital* / Q000473:pathology