Copacamphane, picrotoxane, and alloaromadendrane sesquiterpene glycosides and phenolic glycosides from Dendrobium moniliforme.
Seven sesquiterpene glycosides with copacamphane, picrotoxane, and alloaromadendrane sesquiterpene aglyons along with three phenolic glycosides have been isolated from the stems of Dendrobium moniliforme. Among them, dendromonilisides A-D (1-4) were characterized as new compounds, and their structures were determined on the basis of spectral and chemical methods and by X-ray diffraction analysis. The six known compounds were identified as dendrosides A, C, and F, dendromoniliside E, vanilloloside, and acanthoside B. In a preliminary biological test procedure, compounds 1, 3, and vanilloloside were found to stimulate the proliferation of B cells and inhibit the proliferation of T cells in vitro.
Zhao
Chunsheng
C
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
Liu
Qunfang
Q
Halaweish
Fathi
F
Shao
Baoping
B
Ye
Yuqing
Y
Zhao
Weimin
W
D052176:Azulenes; D001402:B-Lymphocytes / Q000187:drug effects; D031667:Dendrobium / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014961:X-Ray Diffraction
D052176:Azulenes; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D013729:Terpenes; C419726:alloaromadendrene