title: Detection of bladder cancer using single-photon emission computed tomography of thallium-201: a preliminary report.
abstract: Thallium-201 (Tl-201) is a recognized tumor-imaging agent; however, the usefulness of Tl-201 in bladder cancer has not been studied. The aim of this preliminary study was to evaluate the potential usefulness of Tl-201 in detecting bladder cancer. A total of 14 patients (11 men and 3 women ranging in age from 49 to 80 years) with bladder cancer were arranged for Tl-201 single-photon emission computed tomography (SPECT) of the pelvis. All of the patients had transitional cell carcinoma (TCC). Meanwhile, 7 normal controls (5 men and 2 women; age range: 45-79 years) without any history of pelvic disease also accepted Tl-201 SPECT of the pelvis for comparison. In the result, Tl-201 pelvic SPECT detected bladder cancer in all 14 patients (100.0%). In contrast, all 7 normal controls (100.0%) had negative results of Tl-201 pelvic SPECT. Our study showed that the Tl-201 pelvic SPECT scan could be considered as a useful non-invasive imaging method in detection of bladder cancer.
authors.affiliation: Department of Urology, China Medical College Hospital, No 2, Yuh-Der Road, Taichung 404, Taiwan, R.O.C.
authors.forename: Ching-Chiang
authors.initials: CC
authors.lastname: Yang
authors.forename: Yu-Chien
authors.initials: YC
authors.lastname: Shiau
authors.forename: Shung-Shung
authors.initials: SS
authors.lastname: Sun
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Kao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes