[Clinical analysis of 19 patients with malignant melanoma of the nasal cavity].
OBJECTIVE
To explore the pathology, clinical characteristics and treatment of patients with malignant melanoma of the nasal cavity.


METHODS
From September, 1988 to July, 2001, 19 patients with malignant melanoma of the nasal cavity were treated in our hospital. All the patients were confirmed by histopathology. The most common symptoms were nasal obstruction and epistaxis. All the patients were treated with surgery(S), 6 with S plus radiotherapy (R), 2 with S plus R plus chemotherapy (C), 3 with S plus C.


RESULTS
Seven cases survived for 8 months to 13 years. The survival rates of 1, 3, 5 years were 64.7%, 42.85%, 30.76% respectively.


CONCLUSIONS
Malignant melanoma of the nasal cavity has an aggressive behavior and is easy to recur. S + R is an effective method.
Wei
Rui
R
Department of Radiation Oncology, Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha 410008, China.
Jiang
Wei-hong
WH
Shen
Liang-fang
LF
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000628:therapy; D015996:Survival Rate