Clinical differentiation of acute necrotizing from chronic nonsuppurative pancreatitis in cats: 63 cases (1996-2001).
OBJECTIVE
To characterize clinical, clinicopathologic, radiographic, and ultrasonographic findings in cats with histologically confirmed acute necrotizing pancreatitis (ANP) or chronic nonsuppurative pancreatitis (CP) and identify features that may be useful in the antemortem differentiation of these disorders.


METHODS
Retrospective study.


METHODS
63 cats with histologically confirmed ANP (n = 30) or CP (33).


METHODS
Medical records were reviewed for signalment, clinical signs, concurrent diseases, clinicopathologic findings, and results of radiography and ultrasonography.


RESULTS
Cats in both groups had similar nonspecific clinical signs, physical examination findings, and radiographic and ultrasonographic abnormalities. Abdominal ultrasonographic abnormalities, including hypoechoic pancreas, hyperechoic mesentery, and abdominal effusion, were found in cats in both groups and, therefore, were not specific for ANP. Cats with CP were significantly more likely to have concurrent diseases than were cats with ANP (100 and 83%, respectively). Clinicopathologic abnormalities were similar between groups; however, serum alanine aminotransferase and alkaline phosphatase activities were significantly higher in cats with CP.


CONCLUSIONS
Results suggest that ANP and CP in cats cannot be distinguished from each other solely on the basis of history, physical examination findings, results of clinicopathologic testing, radiographic abnormalities, or ultrasonographic abnormalities.
Ferreri
Jean A
JA
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Hardam
Erin
E
Kimmel
Susan E
SE
Saunders
H Mark
HM
Van Winkle
Thomas J
TJ
Drobatz
Kenneth J
KJ
Washabau
Robert J
RJ
D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002415:Cats; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D008297:Male; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology*; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D010808:Physical Examination / Q000662:veterinary; D011860:Radiography, Abdominal / Q000662:veterinary; D012189:Retrospective Studies; D012698:Serologic Tests / Q000662:veterinary; D014463:Ultrasonography