title: Short- and intermediate-term follow-up results of percutaneous transluminal balloon valvuloplasty in adolescents and young adults with congenital pulmonary valve stenosis.
abstract: Percutaneous pulmonary balloon valvuloplasty (PBV) is a well-established treatment alternative to surgery in many cardiology centers. We described our experience with PBV in 25 adolescent and young adult patients with isolated pulmonary valve stenosis (PVS). Among 20 successful PBVs, there was a significant immediate decrease in right ventricular systolic pressure from 116.9 32.4 mmHg to 60.5 18.7 mmHg (p < 0.0001) and a decrease in transpulmonary valve pressure gradient from 93.5 32.8 mmHg to 33.5 9.7 mmHg (p < 0.0001) was noted. The follow-up period was 1-5 years (mean = 3.2 1.2 years), during which patients were periodically assessed by Doppler echocardiogram. During follow-up, the transpulmonary valve pressure gradient further decreased from 33.5 9.7 mmHg to 18.6 3.4 mmHg (p < 0.0001) mainly due to regression of infundibular hypertrophy. Thus, the study showed excellent short-term and intermediate-term results of PBV.
authors.affiliation: National Institute of Cardiovascular Disease, Karachi, Pakistan. saleem_sharieff@hotmail.com
authors.forename: Saleem
authors.initials: S
authors.lastname: Sharieff
authors.forename: Khan
authors.initials: K
authors.lastname: Shah-e-Zaman
authors.forename: Azhar Masood A
authors.initials: AM
authors.lastname: Faruqui
mesh_terms: D000293:Adolescent; D000328:Adult; D002404:Catheterization / Q000379:methods*; D017023:Coronary Angiography; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000151:congenital* / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome