title: [Acute coronary syndrome is a common clinical manifestation of in-stent restenosis].
abstract: OBJECTIVE
  To study the common clinical manifestations of in-stent restenosis.
  
  
  METHODS
  Of 431 patients who underwent percutaneous coronary intervention and repeat catheterization between January 1, 1996 and December 31, 2002, 236 consecutive patients with recurrent ischemia and restenosis were identified: 188 patients with (group I) and 48 without (group II) stenting. Patients who developed early acute stent thrombosis were excluded from the study. In the study we compared the clinical manifestations of in-stent restenosis with those of restenosis without stenting.
  
  
  RESULTS
  Recurrent clinical ischemia occurred at a mean of 5.3 months in group I and 6.1 months in group II (P > 0.05). Rest angina (Braunwald class 2 and 3, 43% vs 27%, P < 0.05), the combination of rest angina and acute myocardial infarction (43% vs 27%, P < 0.05), and angiographically visible thrombosis (7% vs 0%, P < 0.05) were more frequent in group I than in group II.
  
  
  CONCLUSIONS
  Acute coronary syndromes are the common clinical manifestations of restenosis in patients undergoing percutaneous coronary intervention and occur more frequently in patients with in-stent stenosis than in those with restenosis without stenting.
authors.affiliation: Department of Cardiology, The Third Hospital of Peking University, Beijing 100083, China. zhangy_zhen@yahoo.com
authors.forename: Yong-zhen
authors.initials: YZ
authors.lastname: Zhang
authors.forename: Jie-ming
authors.initials: JM
authors.lastname: Mao
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Guo
authors.forename: Fu-chun
authors.initials: FC
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Niu
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Li
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis*; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*; D015607:Stents