title: [Effect of low-power laser irradiation on the structure and properties of protein molecules under non-specific energy absorbance].
abstract: The influence of the helium-neon laser emission on HSA was investigated at present work by means of the fluorescent probe MNBIS (4-morpholino-7-oxy-7-H-benzo-[de]-benzo-[4,5]-imidazo-[2,1-a]- izoquinolin-5-sulfonic acid) sensitive to protein conformational changes using. Fluorescence spectra parameters of the probe and kinetics of probe interaction with protein molecules were analyzed. Possible mechanisms of the helium-neon laser irradiation on water-protein solution structure are discussed.
authors.affiliation: Laser Biology and Laser Medicine Research Iinstitute, V.N. Karazin Kharkov National University.
authors.forename: E O
authors.initials: EO
authors.lastname: Romodanova
authors.forename: T S
authors.initials: TS
authors.lastname: Diubko
authors.forename: T F
authors.initials: TF
authors.lastname: Morozova
authors.forename: O D
authors.initials: OD
authors.lastname: Roshal'
authors.forename: V B
authors.initials: VB
authors.lastname: Distanov
authors.forename: Iu O
authors.initials: IuO
authors.lastname: Hurkalenko
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry / Q000528:radiation effects; D006371:Helium; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007834:Lasers; D015394:Molecular Structure; D009356:Neon; D011485:Protein Binding; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000528:radiation effects*; D011829:Radiation Dosage; D012709:Serum Albumin / Q000737:chemistry / Q000528:radiation effects; D012996:Solutions / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014364:Tryptophan / Q000737:chemistry; D014443:Tyrosine / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D011506:Proteins; D012709:Serum Albumin; D012996:Solutions; D014867:Water; D006371:Helium; D014443:Tyrosine; D009356:Neon; D014364:Tryptophan