[Prevention of diabetic nephropathy: from microalbuminuria to end-stage renal insufficiency].
Diabetic nephropathy is one of the leading causes of end-stage renal failure in western countries. This disease develops over several years. Early stages, if they are detected in time, can lead to preventive treatment at a moment when the disease is still reversible. This paper reviews the main primary and secondary preventive measures that have been proven efficacious. Those are essentially the optimal treatment of hyperglycaemia and hypertension, and probably the use of agents that specifically block the renin-angiotensin axis. We briefly discuss the results of the main studies that have led to those conclusions.
Weekers
L
L
Service de Néphrologie et de Diabétologie, Nutrition et Maladies métaboliques, CHU Sart Tilman, Liège. L.Weekers@chu.ulg.ac.be
Scheen
A J
AJ
Rorive
G
G
D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000209:etiology / Q000517:prevention & control*; D003928:Diabetic Nephropathies / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000517:prevention & control*