Myeloid sarcoma of both kidneys, the brain, and multiple bones in a nonleukemic child.
A myeloid sarcoma (MS) is an extramedullary tumor consisting of primitive granulocytic precursor cells. Although most such tumors have been reported in patients with acute myelogenous leukemia, MS is rarely recognized as an isolated tumor without any evidence of leukemia. However, in such cases, the initial diagnosis of MS can be difficult, so initial misdiagnosis rates of up to 75% have been reported. This report describes an unusual case of MS in a 3-year 5-month-old girl presenting as bilateral renal enlargements, and brain masses, with multiple bone involvements, but no hematological abnormalities.
Park
Hyeon-Jin
HJ
Department of Pediatrics, Chungbuk National University Hospital, 62 Kaeshin- dong, Heungdok-gu, Cheongju, Chungbuk 361-711, Korea. hjpark@chungbuk.ac.kr
Jeong
Dong-Ho
DH
Song
Hyung-Geun
HG
Lee
Geon-Kook
GK
Han
Gi-Seok
GS
Cha
Sang-Hoon
SH
Ha
Tae-Sun
TS
D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D023981:Sarcoma, Myeloid / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed