title: Long-term results of endoscopic removal of large colorectal adenomas.
abstract: OBJECTIVE
  Endoscopic removal of large colorectal polyps has not been widely accepted. The aims of this study were to evaluate our longterm experiences justifying endoscopic resection technique as the treatment of choice.
  
  
  METHODS
  During a period of 12 years, 288 patients with a total of 302 polyps larger than 3 cm in diameter were treated endoscopically. 224 polyps were sessile and 78 pedunculated. Sessile polyps were removed using the piecemeal technique. Surgery was recommended in patients with unfavorable histology. Patients with favorable histology were followed up at 3 - 6 month intervals in the first year and then every 1 - 2 years.
  
  
  RESULTS
  A total of 184 patients with sessile polyps were followed up for at least 6 months. Recurrence rate of 166 benign polyps was 17 % (29/166). Only two patients had malignant recurrence. 8 of 18 patients with malignant polyps underwent surgery while 10 were unfit for surgery. 8 of these patients remained free of recurrence.
  
  
  CONCLUSIONS
  Previous concerns about endoscopic removal of large colorectal polyps are no longer justified. The results of this study showed that endoscopic resection of large colorectal polyps is safe and effective. In patients with high operative risk, endoscopic removal may be adequate.
authors.affiliation: Department of Interdisciplinary Endoscopy, University Hospital Eppendorf, Hamburg, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Seitz
authors.forename: S
authors.initials: S
authors.lastname: Bohnacker
authors.forename: S
authors.initials: S
authors.lastname: Seewald
authors.forename: F
authors.initials: F
authors.lastname: Thonke
authors.forename: N
authors.initials: N
authors.lastname: Soehendra
mesh_terms: D000236:Adenoma / Q000473:pathology* / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors