[Allergy to mould allergens as a risk factor for bronchial asthma in patients suffering from allergic rhinitis].
The ARIA study demonstrates the correlation between bronchial asthma (BA) and perennial rhinitis (PR) with mite or animal fur allergies. There are no reports concerning correlation between BA and PR with mould allergy. The authors of this study estimated the prevalence of BA in patients with PR, allergic to moulds in comparison with patients allergic to other aeroallergens. 460 patients suffering from PR were investigated: 102 were allergic to moulds (mono- or multisensitization type) and 358 were allergic to other allergens. The prevalence of BA in mould-sensitive and insensitive patients was 70.6% and 43.6%, respectively; it was significantly higher in the mould-sensitive group (p = 0.004) regardless of the type of mould hypersensitivity (mono- or multisensitization). The higher prevalence of BA in mould-sensitive patients was found to be valid only for adults. The adult PR patients with diagnosed BA were most frequently allergic to Alternaria (47.1%) and Cladosporium (30.8%).


CONCLUSIONS
mould allergy may be a risk factor for BA development.
Bogacka
Ewa
E
Klinika Chorób Wewnetrznych i Alergologii Akademii Medycznej we Wrocławiu.
Nittner-Marszalska
Marita
M
Fal
Andrzej M
AM
Kuzniar
Jolanta
J
Nikiel
Elzbieta
E
Małolepszy
Józef
J
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000276:immunology* / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000150:complications*; D012307:Risk Factors; D013172:Spores, Fungal / Q000276:immunology*