[A study of the genetic basis of susceptibility to occupational fluorosis in aluminum industry workers of Siberia].
The phenotype frequency distributions of several classical blood genetic markers and dermatoglyphic characters were analyzed in workers of Siberian aluminum plants who had occupational fluorosis. Comparison with healthy workers revealed significant differences in frequencies of several markers. Phenotypes B (AB0), D (Rh), MN (MN), P1 (P), Le a (Lewis), Gc 2-1, Cx (on both hands), Th/I+ (on the left hand), C3, and C4 (HLA) were associated with higher risk of occupational fluorosis.
Lavriashina
M B
MB
Department of Human and Animal Zoology, Kemerovo State University, Kemerovo, 650043 Russia.
Ul'ianova
M V
MV
Druzhinin
V G
VG
Tolochko
T A
TA
D000017:ABO Blood-Group System / Q000235:genetics; D000535:Aluminum; D003878:Dermatoglyphics; D004912:Erythrocytes / Q000502:physiology; D005458:Fluoride Poisoning / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics; D006225:Hand / Q000033:anatomy & histology; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D008297:Male; D008669:Metallurgy; D009784:Occupational Diseases / Q000235:genetics*; D016273:Occupational Exposure; D012204:Rh-Hr Blood-Group System / Q000235:genetics; D012800:Siberia
D000017:ABO Blood-Group System; D006680:HLA Antigens; D012204:Rh-Hr Blood-Group System; D000535:Aluminum