Antisaccade performance of 1,273 men: effects of schizotypy, anxiety, and depression.
A total of 1,273 conscripts of the Greek Air Force performed antisaccades and completed self-reporting questionnaires measuring schizotypy and current state-dependent psychopathology. Only 1.0% of variability in antisaccade performance indices was related to psychometric scores in the population and could be attributed more to current state-dependent symptoms such as anxiety rather than to schizotypy. In contrast, a specific increase of error rate and response latency variability and a high correlation of these 2 variables was observed in a group with very high schizotypy scores. This effect was independent of anxiety and depression, suggesting that a specific group of psychosis-prone individuals has a characteristic deviance in antisaccade performance that is not present in the general population.
Smyrnis
Nikolaos
N
University Mental Health Research Institute, Neurology Department, National University of Athens, Greece. smyrnis@med.uoa.gr
Evdokimidis
Ioannis
I
Stefanis
Nicholas C
NC
Avramopoulos
Dimitrios
D
Constantinidis
Theodoros S
TS
Stavropoulos
Alexios
A
Stefanis
Costas N
CN
D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008297:Male; D012438:Saccades / Q000502:physiology*; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000453:epidemiology*