title: [Botulinum toxin injection into the cricopharyngeal muscle for dysphagia: report of 2 successful cases].
abstract: Dysphagia is frequently observed in patients with sequelae after multiple cerebral infarctions and those with neuromyopathy. Dysphagia in these patients can be successfully treated by laryngeal suspension and cricopharyngeal myotomy. Surgery is not indicated in senile patients with serious complications, where conservative treatment is performed. We injected botulinum toxin into the right cricopharyngeal muscle with excellent results in two dysphagic patients with multiple cerebral infarction who refused surgery. There two cases developed dysphasia after multiple cerebral infarction, where surgical therapy was not indicated. Dysphagia is successfully treated by 5 units of botulinum toxin injected into the cricopharyngeal muscle. Botulinum toxin injection is considered useful for dysphagia in patients in whom surgery is not indicated. The effect of botulinum toxin lasts for 3 to 4 months. Injection of botulinum toxin is useful for patients with temporary dysphasia after cerebral infarction and soon improves swallowing with the assistance of rehabilitation.
authors.affiliation: Department of Otorhinolaryngology, Teikyo University School of Medicine, Ichihara Hospital, Ichihara.
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Masao
authors.initials: M
authors.lastname: Asai
authors.forename: Masanobu
authors.initials: M
authors.lastname: Kumada
authors.forename: Shinji
authors.initials: S
authors.lastname: Usui
authors.forename: Takeo
authors.initials: T
authors.lastname: Kobayasi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001905:Botulinum Toxins / Q000008:administration & dosage*; D002544:Cerebral Infarction / Q000150:complications; D003680:Deglutition Disorders / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D010609:Pharyngeal Muscles
chemical_list: D001905:Botulinum Toxins