title: Study of stereoselective synthesis of (+/-)-neocnidilide.
abstract: Neocnidilide 1, isolated from Apium graveleues L (Umbelliferae), has shown activity to inhibit the growth of mycotoxin-producing fungi. An efficient method for the synthesis of the racemic neocnidilide by the stereoselective reaction of hemiacetal 6 with n-BuMgBr has been developed.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
authors.forename: Xiao-Zhen
authors.initials: XZ
authors.lastname: Jiao
authors.forename: Ping
authors.initials: P
authors.lastname: Xie
authors.forename: Lian-Suo
authors.initials: LS
authors.lastname: Zu
authors.forename: Xiao-Tian
authors.initials: XT
authors.lastname: Liang
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D004365:Drugs, Chinese Herbal; D008968:Molecular Conformation
chemical_list: D001572:Benzofurans; D004365:Drugs, Chinese Herbal; C087913:neocnidilide