Serious allergic reaction to administration of epirubicin.
A 47-year old woman was admitted for adjuvant treatment with chemotherapy consisting of epirubicin and cyclophosphamide. During the second course of chemotherapy an allergic reaction occurred after administration of epirubicin. Treatment with clemastine 2 mg iv caused a quick recovery and after 24 hours there was only a slight redness of the face. A discussion follows on allergic reactions to antracyclines and the literature is updated.
Oltmans
R
R
Department of Internal Medicine, Mesos Medical Centre, van Heuven Goedhartlaan 1, 3527 CE Utrecht, the Netherlands.
van der Vegt
S G L
SG
D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D015251:Epirubicin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged
D000903:Antibiotics, Antineoplastic; D015251:Epirubicin