[Bacteremia caused by Enterococcus gallinarum with a high level of glycopeptide resistance: 1st documented cases in Argentina].
A case of bacteremia due to high-level-vancomycin- (MIC = 64 micrograms/ml) and high-level-teicoplanin- (MIC = 32 micrograms/ml) resistant Enterococcus gallinarum is described. Both genes, van C1 and van A, respectively conferring natural low-level resistance and acquired high-level resistance to vancomycin, were found in the enterococcal genoma. The present is the first report of an E. gallinarum isolate showing the van A genotype in Argentina.
Togneri
A
A
Hospital Interzonal General de Agudos Evita, Lanús, Provincia de Buenos Aires, Argentina.
Lopardo
H
H
Corso
A
A
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001118:Argentina / Q000453:epidemiology; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D001426:Bacterial Proteins / Q000032:analysis / Q000235:genetics; D019729:Carbon-Oxygen Ligases / Q000032:analysis / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D016983:Enterococcus / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D017809:Fatal Outcome; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000382:microbiology; D017334:Teicoplanin / Q000494:pharmacology*; D014640:Vancomycin / Q000494:pharmacology*; D020713:Vancomycin Resistance / Q000235:genetics
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C071437:VanA ligase, Bacteria; D017334:Teicoplanin; D014640:Vancomycin; D019729:Carbon-Oxygen Ligases