title: Copacamphane, picrotoxane, and alloaromadendrane sesquiterpene glycosides and phenolic glycosides from Dendrobium moniliforme.
abstract: Seven sesquiterpene glycosides with copacamphane, picrotoxane, and alloaromadendrane sesquiterpene aglyons along with three phenolic glycosides have been isolated from the stems of Dendrobium moniliforme. Among them, dendromonilisides A-D (1-4) were characterized as new compounds, and their structures were determined on the basis of spectral and chemical methods and by X-ray diffraction analysis. The six known compounds were identified as dendrosides A, C, and F, dendromoniliside E, vanilloloside, and acanthoside B. In a preliminary biological test procedure, compounds 1, 3, and vanilloloside were found to stimulate the proliferation of B cells and inhibit the proliferation of T cells in vitro.
authors.affiliation: Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Zhao
authors.forename: Qunfang
authors.initials: Q
authors.lastname: Liu
authors.forename: Fathi
authors.initials: F
authors.lastname: Halaweish
authors.forename: Baoping
authors.initials: B
authors.lastname: Shao
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Ye
authors.forename: Weimin
authors.initials: W
authors.lastname: Zhao
mesh_terms: D052176:Azulenes; D001402:B-Lymphocytes / Q000187:drug effects; D031667:Dendrobium / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D052176:Azulenes; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D013729:Terpenes; C419726:alloaromadendrene