Palladium-catalyzed intermolecular alpha-arylation of N-protected 2-piperidinones.
[reaction: see text] The alpha-arylation of the zinc enolate of N-protected 2-piperidinones with aryl bromides in the presence of a palladium catalyst is described as a general method.
Cossy
Janine
J
Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France. janine.cossy@espci.fr
De Filippis
Arnault
A
Pardo
Domingo Gomez
DG