Syngeneic graft-versus-host disease: a report of two cases and literature review.
Rappeport et al first reported the clinical syndrome of graft-versus-host disease (GVHD) in syngeneic bone marrow transplant patients. Recently, there have been more reports of a GVHD-like syndrome in syngeneic bone marrow transplant patients (SGVHD) that may result in significant clinical morbidity. A total of 17 cases of SGVHD in syngeneic bone marrow transplant patients have been reported to date in the medical literature. The current report reviews these cases and presents two additional cases of severe SGVHD that have occurred at our institution.
Latif
T
T
Department of Hematology and Medical Oncology, Taussig Cancer Center, Cleveland, OH 44195, USA.
Pohlman
B
B
Kalaycio
M
M
Sobecks
R
R
Hsi
E D
ED
Andresen
S
S
Bolwell
B J
BJ
D000328:Adult; D015551:Autoimmunity; D016026:Bone Marrow Transplantation / Q000009:adverse effects* / Q000276:immunology; D006086:Graft vs Host Disease / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006087:Graft vs Host Reaction; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D012008:Recurrence; D014185:Transplantation, Isogeneic / Q000009:adverse effects*
D007166:Immunosuppressive Agents