title: Study of the fragmentation mechanism of novel functionalized macrocycles by Fourier transform ion cyclotron resonance mass spectrometry.
abstract: Liquid secondary ion mass spectrometry (L-SIMS) of six new functionalized macrocycles was investigated. All six compounds yielded abundant fragment ions and protonation molecular ions [M + H](+) under L-SIMS conditions. The proposed fragmentation mechanisms were supported by high-resolution accurate mass data from Fourier transform ion cyclotron resonance mass spectrometric and MS(n) experiments on using sustained off-resonance irradiation collision-induced dissociation.
authors.affiliation: Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Da-Ming
authors.initials: DM
authors.lastname: Du
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Hua
authors.forename: Meiyu
authors.initials: M
authors.lastname: He
authors.forename: Bin
authors.initials: B
authors.lastname: Xin
mesh_terms: D017357:Cyclotrons; D008401:Gas Chromatography-Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D006571:Heterocyclic Compounds / Q000032:analysis* / Q000737:chemistry; D015394:Molecular Structure; D017550:Spectroscopy, Fourier Transform Infrared / Q000295:instrumentation / Q000379:methods*
chemical_list: D006571:Heterocyclic Compounds