[A comparative evaluation of "cerebral oximetry" during anesthesia with xenon and other anesthetics].
The oxygen status dynamics during the general anesthesia is one of the most important issues of anesthetic monitoring. The set target was to study the cerebral oximetry (rSO2) in anesthesia with xenon as compared with other anesthetics. A total of 80 patients (class ASA I-II) were examined in the venectomy surgery. According to an anaesthetic used in induction and anesthesia management, the patients were divided into 3 groups. Group 1--40 patients with xenon mono-anesthesia; group 2--20 patients with propofol + N2O + neurolpangesia; and group 3--20 patients with N2O + ftorotan. At xenon induction, rSO2 went up by 6.4%. At propofol induction, there were no changes in rSO2. A biggest increase in the cerebral blood circulation was noted, at the anesthesia management stage, in the patients' group, who received ftorotan; a lesser increase was registered in xenon anesthesia. An increased rSO2 level was higher, during the wakening stage, in case of ftorotan administration than in the group, which received xenon; the process of recovering the initial parameters was slower in the former group. Xenon and ftorotan were shown to contribute to a higher oxygen status and an increased volume of the cerebral blood circulation. In case of xenon mono-anesthesia, there was a smaller increase in the cerebral blood circulation as compared to N2O + ftoratan anesthesia. Further special investigations are needed to give a final answer to the question on whether it is possible to use xenon in neuroanesthesiology and in intensive care of patients with a neuroresuscitation-type pathology of the brain.
Sal'nikov
P S
PS
Burov
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NE
D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation / Q000379:methods*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D006221:Halothane / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000601:surgery; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000494:pharmacology; D010092:Oximetry / Q000295:instrumentation / Q000379:methods*; D014648:Varicose Veins / Q000601:surgery; D014978:Xenon / Q000008:administration & dosage / Q000494:pharmacology*
D014978:Xenon; D009609:Nitrous Oxide; D006221:Halothane