title: Paraneoplastic sensory neuronopathy and spontaneous regression of small cell lung cancer.
abstract: BACKGROUND
  Spontaneous tumour regression in small cell lung cancer has previously been suggested in patients with paraneoplastic neurologic syndromes. Rare documentation of this event has occurred in the literature.
  
  
  METHODS
  The authors report a patient with anti-Hu associated paraneoplastic sensory neuronopathy who had a spontaneous regression of her small cell lung cancer.
  
  
  CONCLUSIONS
  This case supports the hypothesis that anti-Hu neurologic syndromes are the consequence of a misdirected immune response to small cell tumours.
authors.affiliation: Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada.
authors.forename: Sharlene
authors.initials: S
authors.lastname: Gill
authors.forename: Nevin
authors.initials: N
authors.lastname: Murray
authors.forename: Josep
authors.initials: J
authors.lastname: Dalmau
authors.forename: Brian
authors.initials: B
authors.lastname: Thiessen
mesh_terms: D000328:Adult; D000906:Antibodies / Q000032:analysis; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D051959:ELAV Proteins; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D009419:Nerve Tissue Proteins / Q000276:immunology; D009422:Nervous System Diseases / Q000097:blood / Q000150:complications* / Q000276:immunology; D020364:Paraneoplastic Polyneuropathy / Q000097:blood / Q000150:complications* / Q000276:immunology; D016601:RNA-Binding Proteins / Q000276:immunology; D013902:Radiography, Thoracic; D012075:Remission, Spontaneous; D012678:Sensation Disorders / Q000097:blood / Q000150:complications* / Q000276:immunology
chemical_list: D000906:Antibodies; D051959:ELAV Proteins; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins