Changes in peripheral leukocyte populations of weak calf syndrome of Japanese black calves.
To clarify the cellular immune condition in Japanese Black (JB) calves with a weak syndrome, peripheral leukocyte populations were analyzed by flow cytometry. Twenty JB calves were divided into two groups based on clinical observations; one group of calves was weak, because they had experienced an onset of diarrhea within 3 days after birth and needed treatment (Group 1 ;n=10), and the other group of calves was healthy (Group 2; n=10). With regard to leukocyte populations, CD8(+) cells and gamma delta T cells in Group 1 were markedly lower than those in Group 2 during the experimental periods. It is possible that immune-insufficiency might be based on T lymphocyte function in weak syndrome JB calves during the growth process.
Ohtsuka
Hiromichi
H
Department of Veterinary Internal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan.
Fukunaga
Narumi
N
Hara
Hidefumi
H
Fukuda
Sigeo
S
Hayashi
Tomohito
T
Hoshi
Fumio
F
Yoshino
Tomo-o
TO
Koiwa
Masateru
M
Kawamura
Seiichi
S
D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000276:immunology*; D003967:Diarrhea / Q000276:immunology / Q000662:veterinary; D007958:Leukocyte Count; D007962:Leukocytes / Q000145:classification / Q000166:cytology / Q000276:immunology*; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000378:metabolism
D016692:Receptors, Antigen, T-Cell, gamma-delta