[Blood oxygen transport function during ftorotan application in patients with ischemic heart disease and low cardiac output].
A total of 41 patients with ischemic heart disease (IHD) were retrospectively examined after coronary bypass grafting under the conditions of extracorporeal artificial blood circulation and with a combined anesthesia involving ftorotan. The patients were divided into two groups: group 1--11 patients with an initial cardiac index below 33 l x min-1 x m-2 (3.8 +/- 0.27 l x min-1 x m-2. Group 2--30 patients with an initial cardiac index below 2 l x min-1 x m-2 (1.7 +/- 0.04 l x min-1 x m-2, p < 0.01 as compared to group 1). As for group 1, there were reduced parameters, noted at the examination stages, in the oxygen-transport blood function, while they were found to be increased in group 2. Combined anesthesia with ftorotan was not found, in IHD patients with an initial low-output cardiac state, to disrupt essentially the oxygen transport during the pre-perfusion stage. The dynamic changes of the oxygen-transport parameters were shown to be related, in pre-perfusion stage, mainly with peculiarities of hemodynamic changes, in the early operative stage, in patients with different initial cardiac output states.
Naumenko
S E
SE
Belavin
A S
AS
Kim
S F
SF
D000769:Anesthesia, Inhalation / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001692:Biological Transport / Q000187:drug effects; D002303:Cardiac Output, Low / Q000097:blood / Q000601:surgery*; D001026:Coronary Artery Bypass; D006221:Halothane / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000601:surgery*; D010100:Oxygen / Q000097:blood* / Q000378:metabolism; D010101:Oxygen Consumption / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects
D018685:Anesthetics, Inhalation; D010100:Oxygen; D006221:Halothane