title: [Severe acute respiratory syndrome in Guangdong Province of China: epidemiology and control measures].
abstract: OBJECTIVE
  To explore epidemiological features and risk factors of severe acute respiratory syndrome (SARS) in Guangdong Province of China, so as to work out effective strategies for its better control.
  
  
  METHODS
  A total of 1 511 clinically confirmed SARS cases in Guangdong Province of China from November 16, 2002 to Jun 15, 2003 were retrospectively analyzed.
  
  
  RESULTS
  The first SARS case was identified in Foshan municipality on November 16, 2002, followed by 1 511 clinically confirmed cases (including 58 deaths) up to May 15, 2003. Of all cases, health care workers and community family cluster cases accounted for 19.38% and 12.04%. 65.86% SARS patients aged 20 - 49 years, and increased incidence was positively related to their ages. 95.97% cases lived in the following five cities around Pearl Delta Area: Foshan, Guangzhou, Shenzhen, Zhongshan, and Jiangmen. Eleven early reported cases in the communities took animal-related positions. Face-to-face contacts with infected droplets were the main transmission route. An epidemic peak occurred during January 28 to February 26, and those cases accounted for 50.69% of total. Incidence, mortality, and case fatality of SARS were 1.77/100,000, 0.07/100,000, and 3.84% respectively. The mean incubation period was 4.5 days.
  
  
  CONCLUSIONS
  The most effective way to control SARS is to break the chain of transmission from infected to healthy persons-early identification, prompt and effective isolation, and vigorous close contact tracing. Hospital infections among health care workers is critical. Several observations support the hypothesis of an animal origin for the disease.
authors.affiliation: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors.forename: Jian-feng
authors.initials: JF
authors.lastname: He
authors.forename: Rui-heng
authors.initials: RH
authors.lastname: Xu
authors.forename: De-wen
authors.initials: DW
authors.lastname: Yu
authors.forename: Guo-wen
authors.initials: GW
authors.lastname: Peng
authors.forename: Yong-ying
authors.initials: YY
authors.lastname: Liu
authors.forename: Wen-jia
authors.initials: WJ
authors.lastname: Liang
authors.forename: Ling-hui
authors.initials: LH
authors.lastname: Li
authors.forename: Ru-ning
authors.initials: RN
authors.lastname: Guo
authors.forename: Yan
authors.initials: Y
authors.lastname: Fang
authors.forename: Xian-chang
authors.initials: XC
authors.lastname: Zhang
authors.forename: Hui-zhen
authors.initials: HZ
authors.lastname: Zheng
authors.forename: Hui-ming
authors.initials: HM
authors.lastname: Luo
authors.forename: Jin-yan
authors.initials: JY
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D017758:Infectious Disease Transmission, Patient-to-Professional; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology* / Q000517:prevention & control* / Q000635:transmission