title: Conjugated enynes as a new type of substrates for olefin metathesis.
abstract: [reaction: see text] It has been demonstrated for the first time that conjugated enynes can be employed as a facile substrate in olefin metathesis with the use of a bispyridine-substituted ruthenium benzylidene catalyst. Cross-metathesis of the enynes with alkenes turns out to proceed with preferential formation of (Z)-isomers over (E)-isomers up to >25:1 in moderate to good yields. The intramolecular version of conjugated enynes affords novel butadienyl cycloalkenes, which are a highly useful synthetic building blocks, in acceptable yields.
authors.affiliation: Center for Molecular Design and Synthesis, Department of Chemistry and School of Molecular Science (BK21), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
authors.forename: Byungman
authors.initials: B
authors.lastname: Kang
authors.forename: Do-Hyeon
authors.initials: DH
authors.lastname: Kim
authors.forename: Youngkyu
authors.initials: Y
authors.lastname: Do
authors.forename: Sukbok
authors.initials: S
authors.lastname: Chang