title: [Study on the surface-enhanced Raman spectrum of trimethoprim].
abstract: A new method is given in this paper to study the spectra of trimethoprim by using the surface-enhanced Raman spectrum (SERS) technology and the highly efficient thin layer chromatography (TLC) dissociation technology. The results of SERS indicate that the main vibrant spectral band can be obtained by TLC in the samples of about 6 micrograms. The expansion and contraction of pyrimidine ring can be obviously increased and the molecule information can be exactly presented under the action of silver particles.
authors.affiliation: North University of Technology, Beijing 100041, China.
authors.forename: Jin-zhi
authors.initials: JZ
authors.lastname: Zhang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D002855:Chromatography, Thin Layer / Q000379:methods; D005583:Fourier Analysis; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods; D014295:Trimethoprim / Q000737:chemistry*
chemical_list: D011743:Pyrimidines; D012834:Silver; D014295:Trimethoprim