New vessel formation after surgical brain injury in the rat's cerebral cortex II. Formation of the blood vessels distal to the surgical injury.
We investigated the features of newly formed blood vessels after surgical brain injury of the rat's cerebral cortex distal to the operated region. We document the process of split mature blood vessels by an endothelial bridge and morphological features of newly formed vessels. We did not observe a disruption of brain parenchyma. The endothelial lining in vessels was complete. The morphological features of the endothelial cells and basement membrane show that non-sprouting angiogenesis takes place distally to the surgical injury.
Walski
Michał
M
Laboratory of Cell Ultrastructure, Medical Research Centre, Polish Academy of Sciences, 5 Pawiński St., 02-106 Warsaw, Poland.
Frontczak-Baniewicz
Małgorzata
M
D000818:Animals; D001930:Brain Injuries / Q000473:pathology / Q000503:physiopathology*; D002196:Capillaries / Q000502:physiology / Q000648:ultrastructure; D002540:Cerebral Cortex / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D002560:Cerebrovascular Circulation / Q000502:physiology*; D008297:Male; D008854:Microscopy, Electron; D018919:Neovascularization, Physiologic / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar