Suzuki cross-coupling mediated by tetradentate N-heterocyclic carbene (NHC)-palladium complexes in an environmentally benign solvent.
A highly effective, easy to handle and environmentally benign process for palladium mediated Suzuki cross-coupling was developed. By utilizing a solid support based NHC-palladium catalyst, cross couplings of aryl bromides with phenylboronic acid were achieved in neat water under air. A high ratio of substrate to catalyst was also realized.
Zhao
Yuanhong
Y
School of Pharmacy, Yunnan University, Kunming, Yunnan 650091, P. R. China.
Zhou
Yongyun
Y
Ma
Dandan
D
Liu
Jingping
J
Li
Liang
L
Zhang
Tony Y
TY
Zhang
Hongbin
H