title: Quorum sensing by the Lyme disease spirochete.
abstract: The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.
authors.affiliation: Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, MS 415 Chandler Medical Center, Lexington, KY 40536-0298, USA. bstev0@uky.edu
authors.forename: Brian
authors.initials: B
authors.lastname: Stevenson
authors.forename: Kate
authors.initials: K
authors.lastname: von Lackum
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Wattier
authors.forename: Jason D
authors.initials: JD
authors.lastname: McAlister
authors.forename: Jennifer C
authors.initials: JC
authors.lastname: Miller
authors.forename: Kelly
authors.initials: K
authors.lastname: Babb
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D025065:Borrelia burgdorferi / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D013437:Carbon-Sulfur Lyases; D006801:Humans; D008193:Lyme Disease / Q000382:microbiology / Q000635:transmission*
chemical_list: D001426:Bacterial Proteins; D013437:Carbon-Sulfur Lyases; C117753:LuxS protein, Bacteria