Hematopoietic stem cell transplantation for autoimmune diseases in developing countries: current status and future prospectives.
In this paper we present preliminary results of hematopoietic stem cell transplantation for autoimmune diseases in Brazil and China. Chinese experience transplanting lupus is significant and the Brazilian experience with several autoimmune diseases is growing. We discuss peculiar conditions in developing countries which could affect the results, and future prospectives for the organization of phase III randomized trials in those countries.
Voltarelli
J C
JC
Division of Clinical Immunology and Bone Marrow Transplantation Unit, Hospital das Clinicas, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. jcvoltan@fmrp.usp.br
Ouyang
J
J
D001327:Autoimmune Diseases / Q000628:therapy*; D001938:Brazil; D002681:China; D002986:Clinical Trials as Topic; D003906:Developing Countries; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D016896:Treatment Outcome