Protective effects of seabuckthorn seed oil on mouse injury induced by sulfur dioxide inhalation.
Sulfur dioxide (SO2) is a common but important air pollutant. Micronuclei (MN) in the polychromatic erythrocytes (PCE) of mouse bone marrow and the ratio between organ and body weight of treatment mouse were determined and analyzed in vivo in order to study injury of sulfur dioxide inhalation on organs and germ plasm of mouse as well as protective effect of seabuckthorn seed oil against this injury. It was showed that SO2 inhalation induced the change of the ratio between organ and body of mouse organs, such as liver, lung, kidney, and spleen, and a significant increase of number of MNPCE, while seabuckthorn seed oil offered a protection against such injury.
Ruan
Aidong
A
College of Life Science, Zhejiang University, Hangzhou, China.
Min
Hang
H
Meng
Ziqiang
Z
Lü
Zhenmei
Z
D000393:Air Pollutants / Q000493:pharmacokinetics / Q000633:toxicity*; D000818:Animals; D001835:Body Weight; D004912:Erythrocytes; D005260:Female; D031281:Hippophae / Q000737:chemistry*; D019570:Inhalation Exposure; D008297:Male; D051379:Mice; D015162:Micronucleus Tests; D010936:Plant Extracts / Q000494:pharmacology; D010938:Plant Oils / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry; D013458:Sulfur Dioxide / Q000493:pharmacokinetics / Q000633:toxicity*; D014018:Tissue Distribution
D000393:Air Pollutants; D010936:Plant Extracts; D010938:Plant Oils; D013458:Sulfur Dioxide