title: Midazolam-induced sedation for upper gastrointestinal endoscopy: assessment of endoscopist and patient satisfaction.
abstract: Upper gastrointestinal endoscopy can be performed without intravenous sedation but the evidence suggests most patients and endoscopists prefer some form of premedication. Intravenous diazepam or midazolam are used by the majority of endoscopists in the United States, though it is not common practice in Turkey where this study was conducted. This study aimed to evaluate the efficacy and safety of midazolam in performing upper gastrointestinal endoscopy. A total of 352 patients undergoing upper gastrointestinal endoscopy were sedated with midazolam given as a bolus injection over 5 seconds. Ages of the patients ranged between 16 and 79 years (average: 41.6 +/- 12.7 years). The course of endoscopy, anterograde memory, degree of cooperation, degree of sedation, side effects, and acceptability of further intervention were evaluated by a questionnaire given to the patients and endoscopists.
authors.affiliation: Department of Gastroenterology, Endoscopy Unit, Celal Bayar University, Manisa, Turkey. msaruc@hotmail.com
authors.forename: Murat
authors.initials: M
authors.lastname: Saruc
authors.forename: Aysen
authors.initials: A
authors.lastname: Sertdemir
authors.forename: Nurten
authors.initials: N
authors.lastname: Turkel
authors.forename: Isil
authors.initials: I
authors.lastname: Tuzcuoglu
authors.forename: Nuri
authors.initials: N
authors.lastname: Ozden
authors.forename: Hakan
authors.initials: H
authors.lastname: Yuceyar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016099:Endoscopy, Gastrointestinal / Q000451:nursing*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007275:Injections, Intravenous; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D008875:Middle Aged; D017060:Patient Satisfaction; D011292:Premedication; D011795:Surveys and Questionnaires
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam