title: Gamma-pyrone derivatives, kojic acid methyl ethers from a marine-derived fungus Alternaria [correction of Altenaria] sp.
abstract: Kojic acid dimethyl ether (1), and the known kojic acid monomethyl ether (2), kojic acid (3) and phomaligol A (4) have been isolated from the organic extract of the broth of the marine-derived fungus Alternaria sp. collected from the surface of the marine green alga Ulva pertusa. The structures were assigned on the basis of comprehensive spectroscopic analyses. Each isolate was tested for its tyrosinase inhibitory activity. Kojic acid (3) was found to have significant tyrosinase inhibitory activity, but compounds 1, 2, and 4 were found to be inactive.
authors.affiliation: Department of Chemistry, Pukyong National University, Busan 608-737, Korea.
authors.forename: Xifeng
authors.initials: X
authors.lastname: Li
authors.forename: Jee Hean
authors.initials: JH
authors.lastname: Jeong
authors.forename: Kang Tae
authors.initials: KT
authors.lastname: Lee
authors.forename: Jung Rae
authors.initials: JR
authors.lastname: Rho
authors.forename: Hong Dae
authors.initials: HD
authors.lastname: Choi
authors.forename: Jung Sook
authors.initials: JS
authors.lastname: Kang
authors.forename: Byeng Wha
authors.initials: BW
authors.lastname: Son
mesh_terms: D000528:Alternaria / Q000737:chemistry*; D008738:Methyl Ethers / Q000737:chemistry / Q000302:isolation & purification*; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification*; D044445:Ulva / Q000382:microbiology
chemical_list: D008738:Methyl Ethers; D011753:Pyrones; C011890:kojic acid