title: An outbreak of gnathostomiasis among Korean emigrants in Myanmar.
abstract: Thirty-eight (designated as cases) of 60 Korean emigrants who consumed raw fresh water fish in Yangon, Myanmar developed migratory swellings and creeping eruptions on the back, abdomen, flank, and other cutaneous areas 1-10 weeks later. The symptoms included itching, nodule formation, fatigue, urticaria, fever, pain on the skin, and erythematous plaques. Skin biopsies of two cases revealed no parasites. However, the mean +/- SD peripheral blood eosinophilia among the cases was 6.3 +/- 6.5% (n = 29) and 9.0 +/- 9.8% (n = 26) in two examinations. An enzyme-linked immunosorbent assay of their serum samples, using Gnathostoma doloresi adult worms as the antigen, showed mean +/- SD optical densities of 0.47 +/- 0.29 (n = 28) and 0.32 +/- 0.20 (n = 30) in two examinations and 0.12 +/- 0.09 (n = 50) in healthy controls. Two advanced third-stage larvae of G. spinigerum were found in two of six catfish purchased at a local market in Yangon. The outbreak of the human infection is suggested to have been due to G. spinigerum, which is known to live out its life cycle in the Yangon area of Myanmar.
authors.affiliation: Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul, Republic of Korea. cjy@plaza.snu.ac.kr
authors.forename: Jong-Yil
authors.initials: JY
authors.lastname: Chai
authors.forename: Eun-Taek
authors.initials: ET
authors.lastname: Han
authors.forename: Eun-Hee
authors.initials: EH
authors.lastname: Shin
authors.forename: Jae-Hwan
authors.initials: JH
authors.lastname: Park
authors.forename: Jong-Phil
authors.initials: JP
authors.lastname: Chu
authors.forename: Masaki
authors.initials: M
authors.lastname: Hirota
authors.forename: Fukumi
authors.initials: F
authors.lastname: Nakamura-Uchiyama
authors.forename: Yukifumi
authors.initials: Y
authors.lastname: Nawa
mesh_terms: D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004641:Emigration and Immigration; D004802:Eosinophilia / Q000150:complications; D005260:Female; D005399:Fishes / Q000469:parasitology; D016266:Food Parasitology; D006039:Gnathostoma / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007723:Korea / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D002052:Myanmar / Q000453:epidemiology; D012008:Recurrence; D017205:Spirurida Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology