Lateral gene transfer in Salmonella.
Comparative genomics and microarrays reveal that the genomes of different Salmonella enterica serovars are distinguished from each other by the presence or absence of hundreds of genes. The distribution of these variable genome regions is often not clonal. Therefore, lateral gene transfer (LGT) plays an important role in diversity among Salmonella. Overall, almost one quarter of the entire S. enterica sv Typhimurium genome may have been introduced by LGT.
Porwollik
Steffen
S
Sidney Kimmel Cancer Center, 10835 Altman Row, San Diego, CA 92121, USA. sporwollik@skcc.org
McClelland
Michael
M
D022761:Gene Transfer, Horizontal; D014644:Genetic Variation; D016680:Genome, Bacterial; D020411:Oligonucleotide Array Sequence Analysis; D010802:Phylogeny; D012475:Salmonella / Q000145:classification / Q000235:genetics*; D012703:Serotyping