title: Detection of the XXY trisomy in a bull by using sex chromosome painting probes.
abstract: Two cattle chromosome painting probes, identifying X and Y heterosomes, were applied to verify the diagnosis of XXY trisomy in an 8-month-old bull of the Polish Red breed. The probes were obtained after chromosome microdissection and labelled with biotin-16-dUTP. In all metaphase spreads, three fluorescence signals were observed - two X and one Y - confirming the diagnosis of a pure XXY trisomy.
authors.affiliation: Department of Immuno- and Cytogenetics, National Research Institute of Animal Production, ul. Krakowska 1, 32-083 Balice, Poland. eslota@izoo.krakow.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Słota
authors.forename: Anna
authors.initials: A
authors.lastname: Kozubska-Sobocińska
authors.forename: Mariusz
authors.initials: M
authors.lastname: Kościelny
authors.forename: Barbara
authors.initials: B
authors.lastname: Danielak-Czech
authors.forename: Barbara
authors.initials: B
authors.lastname: Rejduch
mesh_terms: D000818:Animals; D002417:Cattle; D020223:Chromosome Painting; D007713:Klinefelter Syndrome / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D008297:Male; D012729:Sex Chromosome Aberrations / Q000662:veterinary; D014314:Trisomy / Q000175:diagnosis*; D014960:X Chromosome; D014998:Y Chromosome