title: Results of the GEP-ISFG collaborative study on the Y chromosome STRs GATA A10, GATA C4, GATA H4, DYS437, DYS438, DYS439, DYS460 and DYS461: population data.
abstract: The Spanish and Portuguese ISFG Working Group (GEP-ISFG) carried out a collaborative exercise in order to asses the performance of two Y chromosome STR tetraplexes, which include the loci DYS461, GATA C4, DYS437 and DYS438 (GEPY I), and DYS460, GATA A10, GATA H4 and DYS439 (GEPY II). The groups that reported correct results in all the systems were also asked to analyse a population sample in order to evaluate the informative content of these STRs in different populations. A total of 1020 males out of 13 population samples from Argentina, Brazil, Costa Rica, Macao, Mozambique, Portugal and Spain were analysed for all the loci included in the present study. Haplotype and allele frequencies of these eight Y-STRs were estimated in all samples. The lowest haplotype diversity was found in the Lara (Argentina) population (95.44%) and the highest (99.90%) in Macao (China). Pairwise haplotype analysis showed the relative homogeneity of the Iberian origin samples, in accordance with what was previously found in the European populations for other Y-STR haplotypes (http://www.ystr.org). As expected, the four non-Caucasian samples, Macao (Chinese), Mozambique (Africans), Costa Rica (Africans) and Argentina (Lara, Amerindians), show highly significant Phist values in the pairwise comparisons with all the Caucasian samples.
authors.affiliation: IPATIMUP, Institute of Pathology and Immunology of University of Porto, Porto, Portugal.
authors.forename: Leonor
authors.initials: L
authors.lastname: Gusmão
authors.forename: Paula
authors.initials: P
authors.lastname: Sánchez-Diz
authors.forename: Cíntia
authors.initials: C
authors.lastname: Alves
authors.forename: Beatriz
authors.initials: B
authors.lastname: Quintáns
authors.forename: Emilio
authors.initials: E
authors.lastname: García-Poveda
authors.forename: Helena
authors.initials: H
authors.lastname: Geada
authors.forename: Eduardo
authors.initials: E
authors.lastname: Raimondi
authors.forename: Sandra María
authors.initials: SM
authors.lastname: Silva de la Fuente
authors.forename: Maria Conceição
authors.initials: MC
authors.lastname: Vide
authors.forename: Martin R
authors.initials: MR
authors.lastname: Whittle
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Zarrabeitia
authors.forename: Mónica
authors.initials: M
authors.lastname: Carvalho
authors.forename: Veranice
authors.initials: V
authors.lastname: Negreiros
authors.forename: Lourdes
authors.initials: L
authors.lastname: Prieto Solla
authors.forename: José A
authors.initials: JA
authors.lastname: Riancho
authors.forename: Rebeca
authors.initials: R
authors.lastname: Campos-Sánchez
authors.forename: Claúdia
authors.initials: C
authors.lastname: Vieira-Silva
authors.forename: Ulises
authors.initials: U
authors.lastname: Toscanini
authors.forename: António
authors.initials: A
authors.lastname: Amorim
authors.forename: Angel
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting / Q000379:methods; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D011174:Portugal; D013030:Spain; D020080:Tandem Repeat Sequences