[Determination of trace palladium in medicament by electric-heated AAS with molybdenum-coated graphite tube].
This paper reports a new method for the determination of palladium in exported medicament doxycycline hydrochloride by graphite furnace atomic absorption spectrometry. The optimum conditions for the determination of trace Pd were investigated in details. When the graphite tube was coated with molybdenum, the sensitivity was enhanced and when EDTA was used as the matrix modifier the matrix interference was eliminated efficiently. The result indicates that the detection limit for Pd is 4.6 x 10(-10) g and the relative standard deviation is 4.3%. The method is accurate and rapid and can be used successfully to determine actual samples. The recovery rate of palladium is in the range of 97.1% to 103.3%.
Lin
Lin
L
Department of Chemistry, Zhengzhou University, Zhengzhou 450052, China.
Han
Hua-yun
HY
Chen
Ke
K
D004318:Doxycycline / Q000737:chemistry*; D004340:Drug Contamination; D006108:Graphite; D006358:Hot Temperature; D008982:Molybdenum; D010165:Palladium / Q000032:analysis*; D012680:Sensitivity and Specificity; D013054:Spectrophotometry, Atomic / Q000379:methods
D010165:Palladium; D006108:Graphite; D008982:Molybdenum; D004318:Doxycycline