title: Effects of passive-avoidance training on sleep-wake state-specific activity in the basolateral and central nuclei of the amygdala.
abstract: This study examined the effects of intense emotional learning on the sleep-wake state-specific electroencephalographic (EEG) activities of the basolateral (BLA) and central (CeA) nuclei of the amygdala. Rats were trained on a passive-avoidance learning (PAL) protocol that was followed by 6 hr of undisturbed polygraphic recording and a PAL test. After PAL training, the total amount of REM sleep decreased: high-frequency EEG power decreased in the CeA during REM sleep and increased in the BLA during all sleep-wake stages. These results suggest that there is no homeostatic demand for REM sleep after intense emotional learning. However, the PAL-specific changes in the local EEG suggest that some form of memory processing may occur within the amygdala during REM sleep.
authors.affiliation: Department of Psychiatry, Boston University School of Medicine, Massachusetts 02118, USA.
authors.forename: Vijayakumar
authors.initials: V
authors.lastname: Mavanji
authors.forename: Donald F
authors.initials: DF
authors.lastname: Siwek
authors.forename: Elissa H
authors.initials: EH
authors.lastname: Patterson
authors.forename: Eric E
authors.initials: EE
authors.lastname: Spoley
authors.forename: Subimal
authors.initials: S
authors.lastname: Datta
mesh_terms: D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001362:Avoidance Learning; D004569:Electroencephalography / Q000662:veterinary; D008297:Male; D008568:Memory; D051381:Rats; D017207:Rats, Sprague-Dawley; D012895:Sleep, REM / Q000502:physiology*