title: Myocardial damage by resuscitation methods.
abstract: Medico-legal autopsy cases were reviewed to detect myocardial changes induced by resuscitation methods. Myofibrillar degeneration (MFD) induced by resuscitation methods was classified into two types according to Luxol fast blue staining: contraction band (CB) and diffuse staining (DS). In the cases in which cardiopulmonary resuscitation had been performed, myocytes showing CB or DS formed small foci and were distributed in the papillary muscles, septum, and inner to middle layers of the myocardium. MFD induced by vasopressors was characterized by solitary distribution of degenerating myocytes that mainly showed DS and sometimes CB. When direct current countershocks had been performed, focal MFD in the subepicardial zone appeared to be a characteristic feature.
authors.affiliation: Department of Legal Medicine, Gifu University School of Medicine, 40 Tsukasamachi, Gifu 500-8705, Japan. bunaiy@cc.gifu-u.ac.jp
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Bunai
authors.forename: Kayoko
authors.initials: K
authors.lastname: Akaza
authors.forename: Masatake
authors.initials: M
authors.lastname: Tsujinaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakazawa
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nagai
authors.forename: Isao
authors.initials: I
authors.lastname: Nakamura
authors.forename: Toru
authors.initials: T
authors.lastname: Nagano
authors.forename: Isao
authors.initials: I
authors.lastname: Ohya
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000009:adverse effects*; D004396:Coloring Agents; D004554:Electric Countershock / Q000009:adverse effects*; D006335:Heart Injuries / Q000473:pathology*; D006801:Humans; D007211:Indoles; D032383:Myocytes, Cardiac / Q000473:pathology; D009210:Myofibrils / Q000473:pathology*; D013194:Staining and Labeling; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D004396:Coloring Agents; D007211:Indoles; D014662:Vasoconstrictor Agents; C018588:Luxol Fast Blue MBS