title: Sex determination in the honeybee.
abstract: Sex determination in honeybees involves a multi-allelic locus, such that homozygotes develop as males and heterozygotes as females. In this issue of Cell, report the cloning of the sex-determining gene, csd. It codes for an SR protein, and different alleles have very different amino-acid sequences. Inactivating csd leads to development as a male.
authors.affiliation: Institute of Cell, Animal, and Population Biology, University of Edinburgh, Ashworth Laboratories, EH9 2BR, Edinburgh, United Kingdom.
authors.forename: Brian
authors.initials: B
authors.lastname: Charlesworth
mesh_terms: D000483:Alleles; D000818:Animals; D001516:Bees / Q000235:genetics* / Q000502:physiology; D005260:Female; D017344:Genes, Insect; D008297:Male; D019849:Sex Determination Processes