title: [Infection control for the treatment of hematological malignancies: a survey of the Kyushu Hematology Organization for Treatment Study Group (K-HOT)].
abstract: The Kyushu Hematology Organization for Treatment Study Group (K-HOT) consisted of 22 institutions specializing in hematology in Kyushu. This study is aimed at reviewing the daily practice of infection control for the treatment of hematological malignancies in our group. Nominal questionnaires were mailed to the hematology department in each institution from November 2001 to April 2002. For the first general surveys, 19 of 22 (86%) institutions responded. The second survey was mailed to the 19 respondents and 17 answered the detailed questionnaires with a response rate of 89%. Prophylactic use of trimethoprim-sulfamethoxazole (ST) against Pneumocystis carinii and anti-mycobacterial drugs in patients who had a history of tuberculosis was routine especially for patients with adult T-cell leukemia/lymphoma (ATL). Furthermore, the neutrophil counts to start a granulocyte-colony stimulating factor appeared to be high in ATL as compared with other hematological malignancies. In the setting of autologous stem cell transplantation (SCT), prophylactic use of acyclovir, immunoglobulin and ST was not routine and was reduced in duration, if used at all, as compared with allogeneic SCT. For allogeneic SCT, the cumulative dose of immunoglobulin significantly varied from institutions to institutions. The benefit of this study is the ability to recognize practical management patterns for infection control.
authors.affiliation: First Department of Internal Medicine, Fukuoka University.
authors.forename: Kenji
authors.initials: K
authors.lastname: Ishitsuka
authors.forename: Syuichi
authors.initials: S
authors.lastname: Ikeda
authors.forename: Youichiro
authors.initials: Y
authors.lastname: Izumi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imamura
authors.forename: Naokuni
authors.initials: N
authors.lastname: Uike
authors.forename: Kimiharu
authors.initials: K
authors.lastname: Uozumi
authors.forename: Atae
authors.initials: A
authors.lastname: Utsunomiya
authors.forename: Fumio
authors.initials: F
authors.lastname: Kawano
authors.forename: Youko
authors.initials: Y
authors.lastname: Kubuki
authors.forename: Hisashi
authors.initials: H
authors.lastname: Gondo
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Saburi
authors.forename: Tsunefumi
authors.initials: T
authors.lastname: Sibuya
authors.forename: Jin
authors.initials: J
authors.lastname: Suzusima
authors.forename: Jyunichi
authors.initials: J
authors.lastname: Tsukada
authors.forename: Makoto
authors.initials: M
authors.lastname: Hayashi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Maeda
authors.forename: Eijyo
authors.initials: E
authors.lastname: Matuishi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Matsuoka
authors.forename: Sigeyoshi
authors.initials: S
authors.lastname: Makino
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tamura
mesh_terms: D019337:Hematologic Neoplasms / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D017053:Infection Control / Q000379:methods*