Regio and diastereoselective lactonisation of enolisable 1,3-dicarbonyls by reaction with mesoionic 1,3-oxazolium-5-olates.
The one-pot reaction of enolisable 1,3-dicarbonyls and N-methyl-1,3-oxazolium-5-olate derivatives provided enol lactones directly in good yield and with excellent regio- and diastereocontrol.
Grassi
Giovanni
G
Dipartimento di Chimica Organica e Biologica, Università, Vill. S. Agata, 1-98166 Messina, Italy. ggrassi@isengard.unime.it
Risitano
Francesco
F
Foti
Francesco
F
Cordaro
Massimiliano
M
Bruno
Giuseppe
G
Nicolò
Francesco
F