Parathyromatosis and recurrent hyperparathyroidism.
Parathyromatosis is an uncommon cause of hypercalcemia. We describe a case of parathyromatosis and hypercalcemia in a 38-year-old man with a history of end-stage renal disease and subtotal parathyroidectomy in which a previous parathyroid operation was implicated. The results of fine-needle aspiration and histologic examination demonstrated a neck mass consistent with parathyromatosis. We discuss parathyromatosis as a rare cause of recurrent hypercalcemia in patients with end-stage renal disease and in those who have undergone previous parathyroid operations. We also characterize the iatrogenic and the embryologic pathogenetic factors involved.
Lentsch
Eric J
EJ
Division of Otolaryngology, Department of Surgery, University of Louisville School of Medicine, Louisville, Ky, USA. ejlent01@louisville.edu
Withrow
Kirk P
KP
Ackermann
Douglas
D
Bumpous
Jeffrey M
JM
D000328:Adult; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D006961:Hyperparathyroidism / Q000209:etiology* / Q000601:surgery; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D010279:Parathyroid Diseases / Q000150:complications*; D016105:Parathyroidectomy; D012008:Recurrence; D013965:Thyroidectomy