Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell-based screening.
A novel cell-permeable DNA fluorescence sensor was developed based on combinatorially-created styryl dyes and cell-based localization screening.
Lee
Jae Wook
JW
Department of Chemistry, New York University, New York, New York 10003, USA.
Jung
Michelle
M
Rosania
Gustavo R
GR
Chang
Young-Tae
YT
D045744:Cell Line, Tumor; D002467:Cell Nucleus / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D008961:Models, Structural; D013050:Spectrometry, Fluorescence / Q000379:methods; D013237:Stereoisomerism
D005456:Fluorescent Dyes; D004247:DNA