title: Predictors of early and late outcome of percutaneous coronary intervention in octogenarians.
abstract: OBJECTIVE
  To evaluate the short and long-term results of percutaneous coronary interventions (PCI) in patients aged 80 years or older and to identify predictors of event-free survival.
  
  
  RESULTS
  Clinical and angiographic data from all patients undergoing percutaneous coronary intervention in our institution are prospectively collected and stored in a computerized database. The clinical and angiographic characteristics of all patients aged 80 years or older undergoing percutaneous coronary intervention between January 1994 and December 1999 were analysed retrospectively. Follow-up was obtained by interview or through the referring physician. One hundred and fifty-eight patients aged 80 years or older (median: 83.4; range: 80.2-92.2) underwent percutaneous coronary intervention in our institution during the study period. The initial angiographic success rate was 92%. In-hospital mortality was 8.2% and procedural success 84.8%. One-year and two-year survival were 81% and 72.2% respectively, while event free survival at 1 year and 2 years was 65.8% and 57%. Using the Cox proportional hazards method, we identified incomplete revascularization and low left ventricular ejection fraction (LVEF) as predictors of death at 2 years. Complete revascularization and stenting were independent predictors of 2-year event-free survival.
  
  
  CONCLUSIONS
  Percutaneous coronary intervention can be performed safely in octogenarians. Complete revascularization, stenting and preserved left ventricular ejection fraction were independent predictors of better outcome in this population.
authors.affiliation: Division of Cardiology, University Hospital, Liège, Belgium.
authors.forename: Olivier
authors.initials: O
authors.lastname: Gach
authors.forename: Olivier
authors.initials: O
authors.lastname: Louis
authors.forename: Christophe
authors.initials: C
authors.lastname: Martinez
authors.forename: Bernard
authors.initials: B
authors.lastname: Lambermont
authors.forename: Paul
authors.initials: P
authors.lastname: Gerard
authors.forename: Victor
authors.initials: V
authors.lastname: Legrand
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003327:Coronary Disease / Q000401:mortality* / Q000628:therapy*; D018572:Disease-Free Survival; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D016016:Proportional Hazards Models; D012044:Regression Analysis; D012189:Retrospective Studies; D016896:Treatment Outcome