When is a stem cell really a stem cell?
While bone marrow transplantation has long been established as an effective approach to the clinical management of a variety of malignant and nonmalignant diseases, the future application of pluripotent stem cells in transplant settings promises to deliver this therapy to a much broader range of indications. In this review, I summarize the emerging field of embryonic stem cell biology in the context of potential clinical applications and regulatory issues.
Spangrude
Gerald J
GJ
Department of Oncological Sciences, Division of Hematology, RM 4C416, University of Utah, 30 N 1900 East, Salt Lake City, UT 84132-2408, USA.
D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D039904:Pluripotent Stem Cells / Q000166:cytology*; D012038:Regeneration; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells; D023822:Tissue Engineering