A facile tetrahydrothiophene-catalyzed ylide route to vinyloxiranes.
Access to vinyloxiranes using aldehydes and allylic bromides in the presence of 1-5 mol% tetrahydrothiophene is reported. Both aliphatic and aromatic aldehydes work well in this reaction and the catalyst loading could be reduced as low as 0.5 mol%.
Li
Kai
K
Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 354 Fenglin Lu, Shanghai 200032, China.
Deng
Xian-Ming
XM
Tang
Yong
Y