Detection of the XXY trisomy in a bull by using sex chromosome painting probes.
Two cattle chromosome painting probes, identifying X and Y heterosomes, were applied to verify the diagnosis of XXY trisomy in an 8-month-old bull of the Polish Red breed. The probes were obtained after chromosome microdissection and labelled with biotin-16-dUTP. In all metaphase spreads, three fluorescence signals were observed - two X and one Y - confirming the diagnosis of a pure XXY trisomy.
Słota
Ewa
E
Department of Immuno- and Cytogenetics, National Research Institute of Animal Production, ul. Krakowska 1, 32-083 Balice, Poland. eslota@izoo.krakow.pl
Kozubska-Sobocińska
Anna
A
Kościelny
Mariusz
M
Danielak-Czech
Barbara
B
Rejduch
Barbara
B
D000818:Animals; D002417:Cattle; D020223:Chromosome Painting; D007713:Klinefelter Syndrome / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D008297:Male; D012729:Sex Chromosome Aberrations / Q000662:veterinary; D014314:Trisomy / Q000175:diagnosis*; D014960:X Chromosome; D014998:Y Chromosome