Lipoblastoma-lipoblastomatosis associated with unilateral limb hypertrophy: a case report in a newborn.
Lipoblastoma is a benign mesenchymal tumor of embryonic adipose tissue, uncommon in infancy. Multicentricity, absence of a capsule and histopathology best defines a lipoblastoma. Synonyms for this lesion are embryonic lipoma, fetal lipoma, lipoblastic tumor, and congenital lipomatoid tumor. Lipoblastoma is more common in males (approximately 80%), is usually located in the subcutaneous soft tissue (benign lipoblastoma) or in the deep interstitium (benign lipoblastomatosis), or sometimes in all corporeal segments. Primary treatment is complete excision. Relapse is between 14-25%, many of which are more "mature," and difficult to differentiate from lipoma. The differential diagnosis includes liposarcoma, which is rare under ten years. Radical excision in children is recommended with relapses, especially with lipoblastomatosis. Chromosomal markers help discriminate between liposarcoma and lipoblastoma.
Papendieck
C M
CM
Universidad del Salvador, ISNA, Instituto Argentino de Diagnóstico y Tratamiento, Buenos Aires, Argentina. cpapen@intramed.net.ar
Barbosa
L
L
Pozo
P
P
Vanelli
C
C
Braun
D
D
Iotti
A
A
D005260:Female; D005534:Foot Diseases / Q000150:complications / Q000151:congenital* / Q000601:surgery; D006801:Humans; D006984:Hypertrophy; D007231:Infant, Newborn; D007866:Leg / Q000473:pathology*; D007870:Leg Length Inequality / Q000209:etiology; D008067:Lipoma / Q000150:complications / Q000151:congenital* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012086:Reoperation; D012983:Soft Tissue Neoplasms / Q000150:complications / Q000151:congenital* / Q000601:surgery