title: Malignant fibrous histiocytoma of the parotid gland.
abstract: Primary malignant fibrous histiocytoma (MFH) arising in a major salivary gland is rare. We encountered a case of MFH affecting the parotid gland. The patient was a 54-year-old man diagnosed as having pleomorphic type of MFH after extended total parotidectomy. Examination of the resected specimen revealed the tumor had not been completely removed. Accordingly treatment consisted in the resection of MFH and radiotherapy in combination with chemotherapy using carboplatin (CBDCA). This postoperative therapy was effective in controlling the growth of the remaining tumor tissue. As the patient showed no signs of local recurrence and distant metastasis for 5 years, plastic surgery was performed to improve the serious deformation of the face with a free anterolateral thigh flap. Our literature review yielded 17 cases of parotid MFH and the 2-year survival rate was 33%.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. skariya@cc.okayama-u.ac.jp
authors.forename: Shin
authors.initials: S
authors.lastname: Kariya
authors.forename: Katsuya
authors.initials: K
authors.lastname: Aoji
authors.forename: Kazushige
authors.initials: K
authors.lastname: Kuyama
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Akagi
authors.forename: Motoharu
authors.initials: M
authors.lastname: Fukazawa
authors.forename: Kazunori
authors.initials: K
authors.lastname: Nishizaki
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland; D018714:Radiotherapy, Adjuvant; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents