title: [Cytogenetic abnormalities in malignant lymphoma and multiple myeloma].
abstract: During the past few years, cytogenetic analysis of malignant proliferations contributed to the resolution of complex heterogeneous pathologic groups in smaller well defined entities. This is particularly true in the field of hematologic malignancies, for acute leukemia as well as for Lymphoma, Hodgkin's disease or multiple myeloma. The improvement of knowledge regarding chromosomal or genetic rearrangements involved in the development of these tumors nowadays allows a better understanding of their pathological mechanisms and a better management of the patients.
authors.affiliation: Laboratoire de génétique oncologique, centre Henri-Becquerel, rue d'Amiens, 76038 Rouen, France. christian.bastard@rouen.fnclcc.fr
authors.forename: C
authors.initials: C
authors.lastname: Bastard
mesh_terms: D002051:Burkitt Lymphoma / Q000235:genetics; D002869:Chromosome Aberrations; D002887:Chromosomes, Human, Pair 18; D020732:Cytogenetic Analysis; D017353:Gene Deletion; D006689:Hodgkin Disease / Q000235:genetics; D006801:Humans; D008223:Lymphoma / Q000235:genetics*; D016393:Lymphoma, B-Cell / Q000235:genetics; D018442:Lymphoma, B-Cell, Marginal Zone / Q000235:genetics; D016403:Lymphoma, Large B-Cell, Diffuse / Q000235:genetics; D020522:Lymphoma, Mantle-Cell / Q000235:genetics; D009101:Multiple Myeloma / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014178:Translocation, Genetic; D014314:Trisomy