Acinospesigenin-A, -B, and -C: three new triterpenoids from Phytolacca acinosa.
Three new triterpenoids, designated as acinospesigenin-A (1), -B (2), and -C (3), isolated from the berries of Phytolacca acinosa, have been characterized as 3 beta-acetoxy-11 alpha,23-dihydroxytaraxer-14-en-28-oic acid, olean-12-en-23-al-2 beta,3 beta-dihydroxy-30-methoxycarbonyl-28-oic acid and olean-12-en-23-al-2 beta,3 beta,11 alpha-trihydroxy-30-methoxycarbonyl-28-oic acid, respectively. The compounds have shown antiedemic activity (LD(50) 10-15 mg/kg mass) in albino rats.
Koul
Summon
S
Department of Chemistry, University of Jammu, Ambedkar Road, Jammu-180006, India.
Razdan
T K
TK
Andotra
C S
CS
D000818:Animals; D004487:Edema / Q000188:drug therapy; D005638:Fruit / Q000737:chemistry; D006614:Hindlimb / Q000187:drug effects; D007194:India; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D029603:Phytolacca / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D014315:Triterpenes; C479244:acinospesigenin A; C479247:acinospesigenin B; C479245:acinospesigenin C