title: [Study on the myocardiac injury in patients with severe acute respiratory syndrome].
abstract: OBJECTIVE
  To explore the myocardiac injury in patients with severe acute respiratory syndrome (SARS) and its clinical significance.
  
  
  METHODS
  37 SARS patients fulfilled the Guangdong provincial diagnostic criteria for infectious atypical pneumonia and 35 health controls were investigated. The serum levels of creatine kinase (CK), lactate dehydrogenase (LDH), aspartate transaminase (AST), troponin I (TnI), creatine kinase-MB (CK-MB) and myoglobin (MYO) were measured.
  
  
  RESULTS
  CK, LDH and AST levels in patients were higher than those of control group (P < 0.01); furthermore, among patients the levels were higher in fatal cases than in survivors. The positive rates of TnI, CK-MB and MYO in patients were higher than those in controls (P < 0.05).
  
  
  CONCLUSIONS
  The patients with SARS are subject to complicating myocardiac injury. Therefore, careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with SARS.
authors.affiliation: Institute of Infectious Diseases, The Eighth People's Hospital of Guangzhou, Guangzhou 510060, China. zhouguand@hotmail.com
authors.forename: Yu-juan
authors.initials: YJ
authors.lastname: Guan
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Tang
authors.forename: Chi-biao
authors.initials: CB
authors.lastname: Yin
authors.forename: Wen-xin
authors.initials: WX
authors.lastname: Hong
authors.forename: Chun-liang
authors.initials: CL
authors.lastname: Lei
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001219:Aspartate Aminotransferases / Q000097:blood; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000209:etiology; D003402:Creatine Kinase / Q000097:blood; D052279:Creatine Kinase, MB Form; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009211:Myoglobin / Q000097:blood; D045169:Severe Acute Respiratory Syndrome / Q000150:complications*; D019210:Troponin I / Q000097:blood
chemical_list: D007527:Isoenzymes; D009211:Myoglobin; D019210:Troponin I; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form