title: Restoration of hearing loss with tissue plasminogen activator. Case report.
abstract: A 59-year-old man with a 2-year history of sudden onset of hearing loss in the left ear was treated with tissue plasminogen activator (tPA) for myocardial infarction. The patient had 50 dB of hearing recovery after the full dose (100 mg of tPA followed by 3 mg/d of tPA for 2 weeks).
authors.affiliation: Department of Otorhinolaryngology, University of Genoa, Genoa, Italy.
authors.forename: Renzo
authors.initials: R
authors.lastname: Mora
authors.forename: Francesco
authors.initials: F
authors.lastname: Mora
authors.forename: Massimilliano
authors.initials: M
authors.lastname: Mora
authors.forename: Marco
authors.initials: M
authors.lastname: Barbieri
authors.forename: T J
authors.initials: TJ
authors.lastname: Yoo
mesh_terms: D001309:Auditory Threshold / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D020127:Recovery of Function / Q000187:drug effects*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator