Malignant fibrous histiocytoma masquerading as germ cell tumor by producing beta-human chorionic gonadotropin and neuron-specific enolase.
Neuron-specific enolase and beta-human chorionic gonadotropin are serum markers frequently found associated with germ cell tumors. To our knowledge, we report the first case of a malignant fibrous histiocytoma producing both markers and discuss the significance of this unusual condition in the differential diagnosis of retroperitoneal tumors.
Froehner
Michael
M
Department of Urology, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.
Theissig
Franz
F
Konopke
Ralf
R
Detlev Saeger
Hans
H
Ockert
Detlef
D
D014408:Biomarkers, Tumor / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D003937:Diagnosis, Differential; D018237:Germinoma / Q000175:diagnosis; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase / Q000032:analysis*; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D010751:Phosphopyruvate Hydratase