RuO4-catalyzed ketohydroxylation of olefins.
A new mild method for the oxidation of a variety of olefins to alpha-hydroxy ketones is described. Using the concept of a nucleophilic reoxidant, different olefins were ketohydroxylated with high regioselectivity in good to excellent yields.
Plietker
Bernd
B
Organic Chemistry II, Chemistry Faculty, Dortmund University, Otto-Hahn-Str. 6, D-44221 Dortmund, Germany. plietker@pop.uni-dortmund.de