title: [Experimental study of magnetic pingyangmycine-bearing microspheres in the treatment of cavernous hemangioma].
abstract: OBJECTIVE
  To investigate the probability and mechanism magnetic pingyangmycine-bearing microspheres(MPMs) in the treatment of cavernous hemangioma.
  
  
  METHODS
  Twenty rabbits were divided into four groups. MPMs, pingyangmycine and magnetic nonpingyangmycine-bearing microspheres were injected into marginal ear veins respectively. All animals were killed after 21 days and histological varations of the veins were observed under the light microscope and transmission electron microscope.
  
  
  RESULTS
  The occlusion of the veins in the group of MPMs with the external magnetic field was more prominent than that in the other groups.
  
  
  CONCLUSIONS
  MPMs can occlude veins by means of its embolized effect and PYM drug effect. MPMs may be better used in the therapy of cavernous hemangioma.
authors.affiliation: Department of Stomatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Zhang
authors.forename: Han-jiang
authors.initials: HJ
authors.lastname: Wu
authors.forename: Tian-you
authors.initials: TY
authors.lastname: Ling
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D001761:Bleomycin / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D004337:Drug Carriers; D016503:Drug Delivery Systems; D005260:Female; D006392:Hemangioma, Cavernous / Q000188:drug therapy*; D008280:Magnetics; D008297:Male; D008863:Microspheres; D011817:Rabbits
chemical_list: D000903:Antibiotics, Antineoplastic; D004337:Drug Carriers; D001761:Bleomycin; C021771:zhengguangmycin