Clinical and pathological features of intracranial chordoma with orbital involvement in a child.
We examined a 44-month-old girl with proptosis of the left eye. Magnetic resonance imaging showed a dumbbell-shaped mass involving the cavernous sinus with orbital extension. Biopsy and immunohistochemistry showed the tumor to be a primitive chordoma. Intracranial chordoma should be considered in the differential diagnosis of children with orbital lesions. Immunohistochemistry is helpful in differentiating chordomas from other primitive round-cell or spindle-cell tumors.
Fleming
Rebecca A
RA
Department of Ophthalmology, University of Tennessee Health Science Center, Memphis 38163, USA.
Wilson
Matthew W
MW
Fuller
Christine E
CE
Fleming
James C
JC
Haik
Barrett G
BG
D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D002817:Chordoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging