Combined metal catalysis and biocatalysis for an efficient deracemization process.
Driven by the demand to enhance the economic balance of chemical processes, the transformation of a racemate into a single stereoisomer (the deracemization process) is one of the most important areas of research. The recent development of the combined use of enzyme and metal catalysis has led to efficient deracemization processes. Dynamic kinetic resolution and cyclic deracemization processes have shown particular promise in this area.
Pàmies
Oscar
O
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.
Bäckvall
Jan E
JE
D000438:Alcohols / Q000737:chemistry; D002384:Catalysis; D020134:Catalytic Domain; D004798:Enzymes / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D004800:Enzymes, Immobilized / Q000737:chemistry; D005656:Fungal Proteins; D007700:Kinetics; D008049:Lipase / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D010084:Oxidation-Reduction; D015202:Protein Engineering / Q000379:methods*; D012428:Ruthenium / Q000737:chemistry; D013237:Stereoisomerism
D000438:Alcohols; D004798:Enzymes; D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D012428:Ruthenium; D008049:Lipase; C431349:lipase B, Candida antarctica