title: Enantiopure beta-hydroxysulfoxide derivatives as novel chiral auxiliaries in asymmetric biaryl Suzuki reactions.
abstract: [reaction: see text] Highly diastereoselective biaryl Suzuki coupling reactions of (1R)-1-(2-iodo or bromophenyl)-2-(R)-(4-tolylsulfinyl)-1-ethanol derivatives with various aryl- or naphthylboronic acids (or esters) were performed with high yields (up to 99%) and an excellent control of the axial chirality (up to 98% de).
authors.affiliation: Laboratoire de stéréochimie associé au CNRS, UMR 7008 Université Louis Pasteur, ECPM 25 rue Becquerel, 67087 Strasbourg Cedex 2, France.
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Broutin
authors.forename: Françoise
authors.initials: F
authors.lastname: Colobert