Deuterated analogues of the free radical trap DEPMPO: synthesis and EPR studies.
Three analogues of 5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide (DEPMPO, 1) labelled with two (1-d2), five (1-d5) or seven (1-d7)2H were synthesized and used to trap the tert-butylperoxyl radical. The EPR spectra of 1-d2-OOBu(t) and 1-d7-OOBu(t) spin adducts exhibited more straightforward patterns and better signal to noise ratio than those obtained with 1 or 1-d5. The use of the easily available 1-d2 as spin trap could help significantly the analysis of the EPR signals when the signal of either superoxide or alkylperoxyl spin adduct is superimposed with the signals of other spin adducts.
Clément
Jean-Louis
JL
Laboratoire SREP, UMR 6517 CNRS et Universités d'Aix-Marseille 1 et 3, Case 521, Avenue Escardrille Normandie-Niemen, 13397 Marseille, France. clement@srepir1.univ-mrs.fr
Finet
Jean-Pierre
JP
Fréjaville
Claudine
C
Tordo
Paul
P