The course of MIB-1 expression by cerebral macrophages following human brain injury.
The course of MIB-1 expression by brain macrophages adjacent to cortical contusions has been immunohistochemically investigated during the first 30 weeks after human brain injury, in order to provide data for a forensic wound age estimation. A positive nuclear staining for MIB-1 could be observed earliest after a postinfliction interval of 3 days and regularly in cases with a survival time between 7 and 14 days, whereas in uninjured brain tissue (control group) no cellular MIB-1 reactivity was visible.
Hausmann
Roland
R
Institute of Legal Medicine, Universitätsstrasse 22, D-91054 Erlangen, Germany. roland.hausmann@recht.imed.uni-erlangen.de
Betz
Peter
P