title: Role of surveillance in intestinal metaplasia of the esophagus and gastroesophageal junction.
abstract: This article reviews current concepts of cancer surveillance in esophageal columnar metaplasia (Barrett's esophagus) and intestinal metaplasia at the gastroesophageal junction. An overview is given of the available data on the prevalence of intestinal metaplasia in biopsies from the distal esophagus and from the gastroesophageal junction. Furthermore, special attention is given to the endoscopic detection of dysplasia and early malignancy. Finally, the costs of endoscopic surveillance and its effect on mortality rates from esophageal adenocarcinoma are discussed.
authors.affiliation: Department of Gastroenterology and Hepatology, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. g.n.tytgat@amc.uva.nl
authors.forename: Guido N J
authors.initials: GN
authors.lastname: Tytgat
authors.forename: Johanna W
authors.initials: JW
authors.lastname: Van Sandick
authors.forename: J Jan B van
authors.initials: JJ
authors.lastname: Lanschot
authors.forename: Huug
authors.initials: H
authors.lastname: Obertop
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology / Q000401:mortality*; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000209:etiology / Q000401:mortality*; D004943:Esophagogastric Junction / Q000473:pathology*; D004945:Esophagoscopy / Q000191:economics; D006801:Humans; D007422:Intestines / Q000473:pathology*; D008679:Metaplasia / Q000150:complications / Q000473:pathology; D011159:Population Surveillance