[Hospital-acquired Streptococcus pneumoniae infection].
Three elderly patients were consecutively found to harbor or to become infected with intermediate-level penicillin-resistant Streptococcus pneumoniae in a hospital respiratory ward. All the isolates from the respective patients produced mucoid-type colonies on sheep blood agar plates and were found to have an identical antibiogram, indicating that those were resistant against erythromycin, clarithromycin, clindamycin and minocycline. Pulse-field gel electrophoresis of genomic DNA digested Sma I and Apa I demonstrated homology among the isolates, which may suggest person-to-person spread in a hospital setting. With this, it is an urgent to establish the institution-based infection control precautions against S. pneumoniae.
Nagata
Kuniaki
K
Tamana Central Hospital.
Ushijima
Masato
M
Yamane
Nobuhisa
N
Miyagi
Chika
C
D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D008297:Male; D010403:Penicillin Resistance; D011008:Pneumococcal Infections / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*