title: Measuring the impact of diagnostic decision support on the quality of clinical decision making: development of a reliable and valid composite score.
abstract: OBJECTIVE
  Few previous studies evaluating the benefits of diagnostic decision support systems have simultaneously measured changes in diagnostic quality and clinical management prompted by use of the system. This report describes a reliable and valid scoring technique to measure the quality of clinical decision plans in an acute medical setting, where diagnostic decision support tools might prove most useful.
  
  
  METHODS
  Sets of differential diagnoses and clinical management plans generated by 71 clinicians for six simulated cases, before and after decision support from a Web-based pediatric differential diagnostic tool (ISABEL), were used.
  
  
  METHODS
  A composite quality score was calculated separately for each diagnostic and management plan by considering the appropriateness value of each component diagnostic or management suggestion, a weighted sum of individual suggestion ratings, relevance of the entire plan, and its comprehensiveness. The reliability and validity (face, concurrent, construct, and content) of these two final scores were examined.
  
  
  RESULTS
  Two hundred fifty-two diagnostic and 350 management suggestions were included in the interrater reliability analysis. There was good agreement between raters (intraclass correlation coefficient, 0.79 for diagnoses, and 0.72 for management). No counterintuitive scores were demonstrated on visual inspection of the sets. Content validity was verified by a consultation process with pediatricians. Both scores discriminated adequately between the plans of consultants and medical students and correlated well with clinicians' subjective opinions of overall plan quality (Spearman rho 0.65, p < 0.01). The diagnostic and management scores for each episode showed moderate correlation (r = 0.51).
  
  
  CONCLUSIONS
  The scores described can be used as key outcome measures in a larger study to fully assess the value of diagnostic decision aids, such as the ISABEL system.
authors.affiliation: Department of Paediatrics, St. Mary's Hospital, London, England.
authors.forename: Padmanabhan
authors.initials: P
authors.lastname: Ramnarayan
authors.forename: Ritika R
authors.initials: RR
authors.lastname: Kapoor
authors.forename: Michael
authors.initials: M
authors.lastname: Coren
authors.forename: Vasantha
authors.initials: V
authors.lastname: Nanduri
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Tomlinson
authors.forename: Paul M
authors.initials: PM
authors.lastname: Taylor
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Wyatt
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Britto
mesh_terms: D001185:Artificial Intelligence; D015510:Clinical Medicine / Q000592:standards*; D003657:Decision Making; D020000:Decision Support Systems, Clinical; D003661:Decision Support Techniques; D003936:Diagnosis, Computer-Assisted; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D006801:Humans; D020407:Internet; D017063:Outcome Assessment, Health Care / Q000379:methods*; D010347:Patient Care Planning; D010372:Pediatrics / Q000592:standards; D011787:Quality of Health Care; D017010:Reminder Systems; D015203:Reproducibility of Results