The diagnosis of functional ovarian cysts using transvaginal ultrasound combined with clinical parameters, CA125 determinations, and color Doppler.
OBJECTIVE
To investigate the role of transvaginal ultrasound combined with clinical parameters, CA125 determinations, and color Doppler in the differentiation between functional cysts and other adnexal masses.


METHODS
Two hundred and eighty-seven consecutive persistent adnexal masses were submitted to B-mode transvaginal ultrasonography associated with color and power Doppler imaging. Plasma CA125 concentrations were measured before surgery.


RESULTS
According to the obtained logistic regression equation, the presence of anechoic tumors without echogenic portions or septa and CA125 <25IU/ml was associated with a 75% probability of presence of follicular cysts. The visualization of fine trabecular jelly-like content or of a heterogeneous mass with hypoechoic content, absent or only peripheral arterial flow, and age <40 years was associated with a 56% probability of presence of luteal cysts.


CONCLUSIONS
Addition of findings to B-mode ultrasonography can help to differentiate functional cysts from other adnexal masses.
Guerriero
Stefano
S
Department of Obstetrics and Gynecology, University of Cagliari, Ospedale San Giovanni di Dio, via Ospedale 46, 09124, Cagliari, Italy. gineca.sgrerriero@tiscali.it
Ajossa
Silvia
S
Lai
Maria Paola
MP
Alcazar
Juan Luis
JL
Paoletti
Anna Maria
AM
Marisa
Orrù
O
Melis
Gian Benedetto
GB
D000293:Adolescent; D000328:Adult; D018394:CA-125 Antigen / Q000097:blood*; D003338:Corpus Luteum; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D010048:Ovarian Cysts / Q000175:diagnosis* / Q000601:surgery; D006080:Ovarian Follicle; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods*; D018615:Ultrasonography, Doppler, Color; D018617:Ultrasonography, Doppler, Pulsed; D014621:Vagina
D018394:CA-125 Antigen