Subcutaneous nodules on the buttocks as a manifestation of dialysis-related amyloidosis: a clinicopathological entity?
While beta 2-microglobulin amyloidosis occurring in patients undergoing long-term dialysis is frequently associated with joint involvement, skin lesions have rarely been encountered. We report a 57-year-old man with extensive subcutaneous amyloid deposition forming large nodules on the buttocks; the patient had been on maintenance dialysis for 28 years. Although this condition is rare, a review of the literature indicates that the majority of such lesions occur around the buttock region.
Shimizu
S
S
Department of Dermatology, Sapporo City General Hospital, North 11, West 13, Chuo-Ku, Sapporo 060-8604, Japan. satoko.shimizu@nifty.ne.jp
Yasui
C
C
Yasukawa
K
K
Nakamura
H
H
Shimizu
H
H
Tsuchiya
K
K
D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology*; D002081:Buttocks; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*