Erythropoietic activity of preparations containing receptors and antibodies to erythropoietin in ultralow doses.
We compared the erythropoiesis-stimulating effects of ultralow doses of erythropoietin receptors and antibodies to erythropoietin in intact mice. Antibodies to erythropoietin, but not erythropoietin receptors, possessed considerable erythropoiesis-activating properties.
Zhdanov
V V
VV
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
Simanina
E V
EV
Dugina
Yu L
YL
Stavrova
L A
LA
Gur'yantseva
L A
LA
Epstein
O I
OI
Dygai
A M
AM
Goldberg
E D
ED
D000740:Anemia / Q000188:drug therapy; D000818:Animals; D000906:Antibodies / Q000494:pharmacology*; D004920:Erythropoiesis / Q000187:drug effects*; D004921:Erythropoietin / Q000276:immunology*; D005260:Female; D051379:Mice; D017467:Receptors, Erythropoietin / Q000378:metabolism
D000906:Antibodies; D017467:Receptors, Erythropoietin; D004921:Erythropoietin