A "magic sandwich" pulse sequence with reduced offset dependence for high-resolution separated local field spectroscopy.
A pulse sequence for high resolution separated local field spectroscopy based on "magic sandwich" elements is demonstrated on a single crystal sample. Simulations and experimental results show that this pulse sequence has a reduced frequency offset dependence compared to PISEMA (polarization inversion spin exchange at the magic angle). As a result, it has a larger effective range of homonuclear decoupling, reduced zero-frequency spectral distortions, and more reliable scale factors for individual resonances. In addition, it is easier to setup on commercial spectrometers.
Nevzorov
Alexander A
AA
Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0307, USA.
Opella
Stanley J
SJ
D003198:Computer Simulation; D003461:Crystallography / Q000379:methods*; D007930:Leucine / Q000031:analogs & derivatives* / Q000737:chemistry*; D008280:Magnetics; D008958:Models, Molecular; D009587:Nitrogen Isotopes; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011522:Protons; D011786:Quality Control; D012815:Signal Processing, Computer-Assisted; D013113:Spin Labels
D009587:Nitrogen Isotopes; D011522:Protons; D013113:Spin Labels; D007930:Leucine; C088117:acetylleucine