Photo recall phenomenon: an adverse reaction to taxanes.
Taxanes are a new group of chemotherapeutic agents, which share some pharmacological characteristics with methotrexate. Methotrexate has previously been reported to cause a photo recall phenomenon which develops 3-5 days after UV radiation, suggesting that taxanes can induce a similar reaction. This should be added to the list of cutaneous side-effects of this class of chemotherapeutic agents. We report a case of photo recall phenomenon in a 55-year-old Chinese woman with metastatic breast cancer who was undergoing chemotherapy with taxanes.
Ee
Hock-Leong
HL
National Skin Center, Singapore, Republic of Singapore. melvinee@nsc.gov.sg
Yosipovitch
Gil
G
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects; D008875:Middle Aged; D017239:Paclitaxel / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology; D012867:Skin
D000964:Antimetabolites, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel; D008727:Methotrexate