Experimental study of antiblastic activity in potentiated antibodies to tumor necrosis factor-alpha.
In mice with Lewis lung carcinoma and melanoma B-16 administration of potentiated antibodies to tumor necrosis factor-alpha started 1 day after transplantation of a small number of tumor cells (10(6)) produced an antiblastic effect.
Amosova
E N
EN
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
Zueva
E P
EP
Razina
T G
TG
Martyushev
A V
AV
Epstein
O I
OI
Krylova
S G
SG
Shilova
N V
NV
D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018827:Carcinoma, Lewis Lung / Q000188:drug therapy; D008545:Melanoma / Q000188:drug therapy; D051379:Mice; D008810:Mice, Inbred C57BL; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
D000906:Antibodies; D000970:Antineoplastic Agents; D014409:Tumor Necrosis Factor-alpha