title: Fat augmentation following microsurgical removal of the vocal nodules: long-term results.
abstract: While the effectiveness of autogenous fat augmentation after microsurgical removal (FAMSR) of the vocal nodules (VN) has been previously shown in patient treatment programs, relatively little information is available regarding the long-term effectiveness of such a procedure. This paper examines, in retrospect, the long-term effectiveness of FAMSR in patients with VN (n = 41) using pre- and post-FAMSR perceptual acoustic and phonatory function data and videolaryngostroboscopic findings for 33 patients. The mean follow-up time was 18 months. Thirty-three (80.4%) patients displayed excellent results; 4 (9.8%) experienced improvement, and 4 (9.8%) postprocedure failure. Patient phonatory functions showed significant improvements in shimmer, harmonic-to-noise ratio, phonation time (p < 0.05), grade, roughness and breathiness (p < 0.001). The videolaryngostroboscopic rating showed significant improvements in vocal fold edge linearity, vocal fold vibration amplitude, and mucosal wave excursion (p < 0.001). Improvements observed through long-term follow-up tended to be less dramatic in patients with recurrent VN than those with nonrecurrent VN. FAMSR is an easy, safe, and fast procedure which should be considered as an option in treating VN patients who either require surgery or do not have the time or perseverance to complete a lengthy program of speech therapy.
authors.affiliation: Department of Otolaryngology, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheunggung Road, Sec. 2, Taipei 114, Taiwan, ROC. hsiunm01kimo@yahoo.com.tw
authors.forename: Ming-Wang
authors.initials: MW
authors.lastname: Hsiung
authors.forename: Yaoh-Shiang
authors.initials: YS
authors.lastname: Lin
authors.forename: Wan-Fu
authors.initials: WF
authors.lastname: Su
authors.forename: Jin-Chin
authors.initials: JC
authors.lastname: Lee
authors.forename: Hsing-Won
authors.initials: HW
authors.lastname: Wang
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications* / Q000601:surgery*; D007828:Laryngoscopy; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D011182:Postoperative Care; D012189:Retrospective Studies; D016896:Treatment Outcome; D014827:Vocal Cords / Q000601:surgery*; D014832:Voice Disorders / Q000209:etiology*; D014833:Voice Quality