title: Clinical and pathological features of intracranial chordoma with orbital involvement in a child.
abstract: We examined a 44-month-old girl with proptosis of the left eye. Magnetic resonance imaging showed a dumbbell-shaped mass involving the cavernous sinus with orbital extension. Biopsy and immunohistochemistry showed the tumor to be a primitive chordoma. Intracranial chordoma should be considered in the differential diagnosis of children with orbital lesions. Immunohistochemistry is helpful in differentiating chordomas from other primitive round-cell or spindle-cell tumors.
authors.affiliation: Department of Ophthalmology, University of Tennessee Health Science Center, Memphis 38163, USA.
authors.forename: Rebecca A
authors.initials: RA
authors.lastname: Fleming
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Wilson
authors.forename: Christine E
authors.initials: CE
authors.lastname: Fuller
authors.forename: James C
authors.initials: JC
authors.lastname: Fleming
authors.forename: Barrett G
authors.initials: BG
authors.lastname: Haik
mesh_terms: D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D002817:Chordoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging