title: [Effects of overdriving pacing preconditioning on the activity of antioxidase in the coronary sinus during the ischemia-reperfusion].
abstract: OBJECTIVE
  To evaluate the effects of early and delayed overdriving pacing preconditioning on the concentration of nitric oxide (NO), superoxide dismutase (SOD) and malondialdehyde (MDA) in blood.
  
  
  METHODS
  Forty-eight rabbits were divided into control (C) group, ischemia-reperfusion (IR) group, overdriving pacing preconditioning (PP) group and delayed protection (DP) group. The concentrations of NO, SOD, MDA in the coronary sinus were detected during the ischemia-reperfusion.
  
  
  RESULTS
  The levels of NO in the coronary sinus of PP and DP group were higher than that of IR group, the levels of MDA of PP and DP group were lower than that of IR group.
  
  
  CONCLUSIONS
  PP and DP could alleviate the injury by the oxygen free radicals during the myocardial ischemia-reperfusion.
authors.affiliation: Department of Emergency, The Affiliated Union Hospital, Fujian Medical University, Fuzhou 350001, Fujian, China.
authors.forename: Xiao-hong
authors.initials: XH
authors.lastname: Lin
authors.forename: Li-ming
authors.initials: LM
authors.lastname: Wu
mesh_terms: D000818:Animals; D054326:Coronary Sinus / Q000503:physiopathology*; D019194:Ischemic Preconditioning; D015428:Myocardial Reperfusion Injury; D009569:Nitric Oxide / Q000378:metabolism*; D011817:Rabbits
chemical_list: D009569:Nitric Oxide