title: Minimal adhesions to ePTFE mesh after laparoscopic ventral incisional hernia repair: reoperative findings in 65 cases.
abstract: OBJECTIVE
  Laparoscopic ventral incisional hernia repair involves intraabdominal placement of a synthetic mesh, and the possibility of formation of severe visceral adhesions to the prosthesis is a principal concern. Little clinical information based on reoperative findings is available about adhesions to biomaterials placed intraabdominally. We conducted a multi-institutional study of adhesions to implanted expanded polytetrafluoroethylene (ePTFE) mesh at reoperation in patients who had previously undergone laparoscopic incisional hernia repair done with the same mesh implantation technique.
  
  
  METHODS
  Nine surgeons retrospectively assessed the severity of adhesions to ePTFE mesh at reoperation in 65 patients. For each case, adhesions were assigned a score of 0 to 3, with 0 indicating no adhesions and 3 severe adhesions.
  
  
  RESULTS
  The mean time from mesh implantation to reoperation was 420 days (range, 2-1 739 days). No adhesions were observed in 15 cases. Forty-four cases received an adhesion score of 1, and 6 cases a score of 2; no scores of 3 were assigned. Thus, 59 patients (91 %) had either no or filmy, avascular adhesions. No enterotomies occurred during adhesiolysis.
  
  
  CONCLUSIONS
  In this large series of reoperations after laparoscopic incisional hernia repair, no or minimal formation of adhesions to implanted ePTFE mesh was observed in 91 % of cases, and no severe cohesive adhesions were found. Comparative analyses of newer materials based on clinical reoperative findings are warranted to assess the safety of intraabdominally placed meshes.
authors.affiliation: Martha's Vineyard Hospital, Oak Bluffs, MA, USA. islandmd@vermontel.net
authors.forename: R H
authors.initials: RH
authors.lastname: Koehler
authors.forename: D
authors.initials: D
authors.lastname: Begos
authors.forename: D
authors.initials: D
authors.lastname: Berger
authors.forename: S
authors.initials: S
authors.lastname: Carey
authors.forename: K
authors.initials: K
authors.lastname: LeBlanc
authors.forename: A
authors.initials: A
authors.lastname: Park
authors.forename: B
authors.initials: B
authors.lastname: Ramshaw
authors.forename: R
authors.initials: R
authors.lastname: Smoot
authors.forename: G
authors.initials: G
authors.lastname: Voeller
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology*; D012086:Reoperation; D012189:Retrospective Studies; D012449:Safety; D013526:Surgical Mesh / Q000009:adverse effects*; D011795:Surveys and Questionnaires; D013997:Time Factors; D000267:Tissue Adhesions / Q000209:etiology*; D014025:Titanium
chemical_list: D011138:Polytetrafluoroethylene; D014025:Titanium