Meningeal tumors of childhood and infancy. An update and literature review.
Meningeal derived tumors of the first 2 decades of life are often diagnostically challenging due to the wide morphologic spectrum encountered and the rarity of most individual entities. The 2 most common patterns include the dural/leptomeningeal-based mass and neoplastic meningitis. Both primary and secondary meningeal presentations may occur, either early or late in the course of various meningothelial, mesenchymal, embryonal, glial, hematopoietic, histiocytic, melanocytic, and inflammatory tumors. As in other areas of pediatric pathology, there are significant differences between this patient cohort and adults, differences which will be emphasized in this review.
Perry
Arie
A
Division of Neuropathology, Washington University School of Medicine, St. Louis, Mo 63110-1093, USA. aperry@pathology.wustl.edu
Dehner
Louis P
LP
D002648:Child; D002675:Child, Preschool; D020022:Genetic Predisposition to Disease; D019337:Hematologic Neoplasms; D018219:Histiocytoma, Benign Fibrous; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008545:Melanoma; D008577:Meningeal Neoplasms / Q000145:classification* / Q000453:epidemiology / Q000473:pathology*; D008579:Meningioma / Q000145:classification / Q000473:pathology*; D008581:Meningitis; D011379:Prognosis; D013997:Time Factors