title: [Role of the L-arginine-NO system in the prevention and treatment of cardiovascular diseases in pregnant women].
abstract: Investigations on using of index possibilities of L-arginin/NO system in evaluation of sanatorium-resort treatment effectiveness of pregnant with cardiovascular disorders were conducted. It was analyzed the dynamics of twenty four hour cycle rhythm of L-arginin and total nitrites and nitrates constance in saliva of 58 pregnant, 20 of which were suffering from metabolic cardiomyopathy, 23-from neurocirculatory dystonia and 15 were healthy pregnant. As the result of examination there were found out considerable changes of parameter values of biological rhythms: duration of rhythm, average twenty four hour cycle range of activity, amount of difference between max index per twenty hour cycle and average index per twenty hour cycle, period of max and min activity. Analysis of tendencies of twenty four hour cycles rhythms concerning dynamics of sanatorium-resort treatment will give possibility to define characteristic features of recovering values of this parameter.
authors.affiliation: Clinical Sanatorium Zovten, Kiev.
authors.forename: O A
authors.initials: OA
authors.lastname: Vladymyrov
authors.forename: N I
authors.initials: NI
authors.lastname: Tofan
mesh_terms: D001120:Arginine / Q000378:metabolism*; D002940:Circadian Rhythm; D005260:Female; D006294:Health Resorts; D006801:Humans; D009566:Nitrates / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D009573:Nitrites / Q000378:metabolism; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control* / Q000628:therapy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012463:Saliva / Q000378:metabolism
chemical_list: D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide; D001120:Arginine