title: Ring forming reactions of imines of 2-aminobenzaldehyde and related compounds.
abstract: By addition of organometallic reagents to 2-aminobenzonitriles followed by quenching with suitable electrophiles (acyl halides, aldehydes and ketones), several types of 6-membered benzofused aromatic and non-aromatic nitrogen heterocycles could be obtained. Rearrangements leading to 1,2-dihydro-3H-1,4-benzodiazepin-3-ones and preparation of various quinazolines are described.
authors.affiliation: Unit for Organic Chemistry, Department of Biosciences, Karolinska Institute and Södertörn University College, Novum Research Park, SE-141 57 Huddinge, Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Wiklund
authors.forename: Jan
authors.initials: J
authors.lastname: Bergman