Facile synthesis of cucurbit[n]uril derivatives via direct functionalization: expanding utilization of cucurbit[n]uril.
A long-standing problem in cucurbituril chemistry is answered through the first direct functionalization of cucurbit[n]uril (CB[n]; n = 5-8)) leading to perhydroxyCB[n] which can be further modified to provide tailored CB[n] derivatives with desired functional groups and good solubility. Anchoring a CB[6] derivative on the surface and its potential application as a sensor are demonstrated. A CB[6] derivative forms nanospheres with possible use in protein and peptide drug delivery.
Jon
Sang Yong
SY
National Creative Research Initiative Center for Smart Supramolecules and Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.
Selvapalam
Narayanan
N
Oh
Dong Hyun
DH
Kang
Jin-Koo
JK
Kim
Soo-Young
SY
Jeon
Young Jin
YJ
Lee
Jae Wook
JW
Kim
Kimoon
K