Dark chocolate inhibits platelet aggregation in healthy volunteers.
Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.
Innes
Andrew J
AJ
University Department of Medicine, Ninewells Hospital and Medical School, Dundee.
Kennedy
Gwen
G
McLaren
Margaret
M
Bancroft
Anne J
AJ
Belch
Jill J F
JJ
D001792:Blood Platelets; D002099:Cacao; D002316:Cardiotonic Agents; D003094:Collagen; D006801:Humans; D015539:Platelet Activation; D010975:Platelet Aggregation Inhibitors; D010979:Platelet Function Tests
D002316:Cardiotonic Agents; D010975:Platelet Aggregation Inhibitors; D003094:Collagen