Synthesis of tetrasubstituted naphthalenes by palladium-catalyzed reaction of aryl iodides with internal alkynes.
The 1:2 coupling of aryl iodides with acetylenedicarboxylate esters and diphenylacetylene efficiently proceeds in the presence of a palladium catalyst with use of silver carbonate as base to produce the corresponding tetrasubstituted naphthalenes.
Kawasaki
Satoshi
S
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Satoh
Tetsuya
T
Miura
Masahiro
M
Nomura
Masakatsu
M