[The effect of semen antisperm antibody on human sperm acrosin activity].
OBJECTIVE
To study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.


METHODS
AsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.


RESULTS
AsAb positive rate was 10.20% in 3,432 case of male infertility, and 9.37% in 2,882 infertile males who received tests of sperm acrosin activity. Acrosin activity of infertility cases were lower than those of fertile cases(P < 0.001). The comparison between AsAb positive group and AsAb negative group infertility cases showed no significant differences of acrosin activity (P > 0.05). Between normal acrosin activity group and abnormal acrosin activity group, there was no significant difference of AsAb positive rate (P > 0.05).


CONCLUSIONS
Antisperm antibody could not affect acrosin activity.
Liu
Rui-Zhi
RZ
Department of Cell Biology, School of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China.
Lu
Ying-Li
YL
Xu
Zong-Ge
ZG
Zuo
Wen-Jing
WJ
Xin
Ji-Li
JL
Wang
Zhong-Shan
ZS
D000176:Acrosin / Q000378:metabolism*; D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D016022:Case-Control Studies; D006801:Humans; D007248:Infertility, Male / Q000276:immunology*; D008297:Male; D012661:Semen / Q000737:chemistry*; D013094:Spermatozoa / Q000201:enzymology* / Q000276:immunology
D001323:Autoantibodies; D000176:Acrosin