title: Outcome of overactive bladder in children.
abstract: One hundred forty-four children with a clinical diagnosis of overactive bladder were observed for a mean of 3.15 +/- 1.92 years. Initial management consisted of a behavioral modification program that included increased fluid intake, a timed voiding schedule and, if applicable, treatment of constipation. Those who failed to improve with the preceding intervention within 10 days to 2 weeks received an anticholinergic medication. Follow-up information was obtained by telephone. Caretakers and/or patients were asked a standard set of questions. The outcome with respect to urinary urgency, urinary frequency, daytime incontinence, posturing and urinary tract infections was recorded. After an average follow-up period of 3 years, 68 (47.2%) of the 144 children recovered from all symptoms of overactive bladder and 61 (42.4%) had decreased symptoms. Fifteen of the children, or 10.4%, still had all of the symptoms originally associated with overactive bladder. Children who had posturing as one of their symptoms had a significantly increased risk of urinary tract infection.
authors.affiliation: The University of Missouri School of Medicine at Kansas City, Missouri, The Children's Mercy Hospital, Kansas City, Missouri 64108, USA.
authors.forename: Stanley
authors.initials: S
authors.lastname: Hellerstein
authors.forename: Amy Ajans
authors.initials: AA
authors.lastname: Zguta
mesh_terms: D001521:Behavior Therapy; D002648:Child; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014555:Urination Disorders / Q000628:therapy*
chemical_list: D018680:Cholinergic Antagonists