title: Intramolecular acylative ring-switching reactions of 3-(tetrahydro-2'-furyl)propanoic acid derivatives to give butanolides: mechanism and scope.
abstract: The mechanism by which dihydro-5-(3'-trifluoroacetoxypropyl)-2(3H)-furanone is formed when 3-(tetrahydro-2'-furyl)propanoic-trifluoroacetic mixed anhydride is treated with an acidic catalyst is defined, and routes to some potentially useful butanolide synthons are described.
authors.affiliation: Centre for Synthesis and Chemical Biology, University Chemical Laboratory, Trinity College, Dublin 2, Ireland.
authors.forename: David H
authors.initials: DH
authors.lastname: Grayson
authors.forename: Una
authors.initials: U
authors.lastname: McCarthy
authors.forename: Edwin D
authors.initials: ED
authors.lastname: Roycroft