[Acute coronary syndrome is a common clinical manifestation of in-stent restenosis].
OBJECTIVE
To study the common clinical manifestations of in-stent restenosis.


METHODS
Of 431 patients who underwent percutaneous coronary intervention and repeat catheterization between January 1, 1996 and December 31, 2002, 236 consecutive patients with recurrent ischemia and restenosis were identified: 188 patients with (group I) and 48 without (group II) stenting. Patients who developed early acute stent thrombosis were excluded from the study. In the study we compared the clinical manifestations of in-stent restenosis with those of restenosis without stenting.


RESULTS
Recurrent clinical ischemia occurred at a mean of 5.3 months in group I and 6.1 months in group II (P > 0.05). Rest angina (Braunwald class 2 and 3, 43% vs 27%, P < 0.05), the combination of rest angina and acute myocardial infarction (43% vs 27%, P < 0.05), and angiographically visible thrombosis (7% vs 0%, P < 0.05) were more frequent in group I than in group II.


CONCLUSIONS
Acute coronary syndromes are the common clinical manifestations of restenosis in patients undergoing percutaneous coronary intervention and occur more frequently in patients with in-stent stenosis than in those with restenosis without stenting.
Zhang
Yong-zhen
YZ
Department of Cardiology, The Third Hospital of Peking University, Beijing 100083, China. zhangy_zhen@yahoo.com
Mao
Jie-ming
JM
Guo
Li-jun
LJ
Zhang
Fu-chun
FC
Niu
Jie
J
Li
Hai-yan
HY
D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis*; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*; D015607:Stents