[The spectroscopic study of the iodine beta-cyclodextrin complexes].
In this paper, the iodine beta-cyclodextrin complexes prepared in different techniques were investigated by Fourier transformation infrared spectrum(FTIR), FT-Raman, Ultra-violet absorption spectrum in qualitative and quantitative analysis. Results showed that the iodine existed in dissociated, bundle and polymerized forms in the complexes. Contras to the method of alcohol craft, the sample prepared in water craft method included a higher capacity of iodine, but it was not stable enough to keep a constant high iodine concentration. This analysis method was simple and convenient, it is useful for quality control of the iodine beta-cyclodextrin complexes raw material medicine.
Song
Z J
ZJ
National Center of Biomedical Analysis, Beijing 100850, China.
Liu
B Y
BY
Qian
X H
XH
Yang
S C
SC
Wei
K H
KH
Zheng
Y H
YH
Ma
X
X
Zhang
H B
HB
D000890:Anti-Infective Agents / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D004355:Drug Stability; D007455:Iodine / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
D000890:Anti-Infective Agents; D002614:Chelating Agents; D003505:Cyclodextrins; D007455:Iodine