[Characteristics of certain components of the systemic inflammatory reaction in patients with diffusive peritonitis].
The clinical, immunobiochemical and hemostasiological parameters of the systemic inflammatory response (SIR) were studied in 51 patients with diffusive peritonitis. The study showed that lactoferrin, plasminogen/plasmin and alpha 2-macroglobulin can be used, in a set, as informative indices of SIR. A reduced content of lactoferrin, a smaller concentration of proteases inhibitor alpha 2-macroglobulin and a higher relation between plasminogen and plasmin correlate with an unfavorable outcome of the disease beginning from the 1st postoperative day. An activity of Willebrandt's factor is a diagnostic and prognostic marker, which determines a lesion to the endothelium system.
Churliaev
Iu A
IuA
Grigor'ev
E V
EV
Sherstobitov
A V
AV
Sibil'
K V
KV
Reĭnik
V Ia
VIa
Martynenkov
V Ia
VIa
D015415:Biomarkers / Q000097:blood; D005341:Fibrinolysin / Q000378:metabolism; D006801:Humans; D007781:Lactoferrin / Q000097:blood; D010538:Peritonitis / Q000097:blood* / Q000150:complications; D010958:Plasminogen / Q000378:metabolism; D011379:Prognosis; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood* / Q000209:etiology; D000511:alpha-Macroglobulins / Q000378:metabolism; D014841:von Willebrand Factor / Q000378:metabolism
D015415:Biomarkers; D000511:alpha-Macroglobulins; D014841:von Willebrand Factor; D010958:Plasminogen; D007781:Lactoferrin; D005341:Fibrinolysin