Unusual skin lesions in chronic myelomonocytic leukemia.
Chronic myelomonocytic leukemia (CMML) is a relatively rare, heterogeneous syndrome classified as a myelodysplastic syndrome according to the French-American-British classification system. The patient's presenting symptom was a pigmented skin nodule that, although common for cases of acute monoblastic leukemia, is peculiar for CMML. This case should increase awareness of the inclusion of CMML in the differential diagnosis of a discolored nodule and highlight the clinicopathologic considerations and therapeutic challenges consistent with the diagnosis of CMML.
McCollum
Amy
A
Division of Hematology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Bigelow
Carolyn L
CL
Elkins
Stephanie L
SL
Hardy
Cheryl L
CL
Files
Joe C
JC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D018450:Disease Progression; D019008:Drug Resistance, Neoplasm; D005145:Face; D005153:Facial Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D015477:Leukemia, Myelomonocytic, Chronic / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology