title: The versatile beta-barrel membrane protein.
abstract: The beta-barrel membrane protein is found in the outer membranes of bacteria, mitochondria and chloroplasts. Approximately 2-3% of the genes in Gram-negative bacterial genomes encode beta-barrels. Whereas there are fewer than 20 known three-dimensional beta-barrel structures, genomic databases currently contain thousands of beta-barrels belonging to dozens of families. New research is revealing the variety of beta-barrel structures and the variety of functions performed by these versatile proteins.
authors.affiliation: Department of Biochemistry SL43, Tulane University Health Sciences Center, New Orleans, LA 70112-2699, USA. wwimley@tulane.edu
authors.forename: William C
authors.initials: WC
authors.lastname: Wimley
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000502:physiology; D002736:Chloroplasts / Q000737:chemistry* / Q000502:physiology*; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000502:physiology; D006090:Gram-Negative Bacteria / Q000737:chemistry* / Q000502:physiology*; D006867:Hydrolases; D008565:Membrane Proteins / Q000737:chemistry* / Q000502:physiology*; D008928:Mitochondria / Q000737:chemistry* / Q000502:physiology*; D018272:Porins; D017434:Protein Structure, Tertiary; D011991:Receptors, Virus / Q000737:chemistry / Q000502:physiology
chemical_list: D001425:Bacterial Outer Membrane Proteins; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D018272:Porins; D011991:Receptors, Virus; C016532:maltoporins; C482905:OmpX protein, E coli; D006867:Hydrolases