title: Sonographic and colour doppler morphology in carcinoma gallbladder.
abstract: Conventional radiography has limitations in accurate diagnosis of gallbladder cancer (GBC). Ultrasonography (USG) allows correct diagnosis in 70-80% advanced and 23% early GBC. Present study was initiated to identify morphology and flow characteristics in GBC using conventional USG and Colour Doppler USG (CD-USG). In 100 patients, USG assessed morphology of mass lesion/wall thickening together with associated features. Of these, 60 cases were studied using CD-USG for intralesional/perilesional vascularity, peak systolic flow velocity (V max), resistive index (RI) and pulsatility index (PI). USG identified GB with mass lesion in 44% cases (Group-I) and only mass in GB fossa in 56% cases (Group-II). Findings identified calculi (73%), liver infiltration (74%), intrahepatic ductal dilatation (IHDD) (52%), lymphadenopathy (19%) and ascites (5%). CD-USG revealed vascularity, mainly pulsatile flow, in 78.3% cases (in 91.3% Group-I cases). Mean Vmax was 0.3037 m/sec (0.109 - 0.646 m/sec.), mean RI was 0.6621 (0.526 - 1.000) and PI was 1.282 (0.772 -2.140), Mean Vmax and PI were higher in Group-I compared to Group-II. Presence of calculus in 73% cases suggests a high association between calculus and malignancy. As flow signals were seen in 78% of all cases and 91.3% Group-I cases undergoing CD-USG, USG and CD-USG together can improve pickup rate of GBC.
authors.affiliation: Department of Radiotherapy, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India.
authors.forename: S
authors.initials: S
authors.lastname: Pradhan
authors.forename: V K
authors.initials: VK
authors.lastname: Shukla
authors.forename: S
authors.initials: S
authors.lastname: Agrawal
authors.forename: V K
authors.initials: VK
authors.lastname: Dixit
authors.forename: O P
authors.initials: OP
authors.lastname: Sharma
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000503:physiopathology; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D003937:Diagnosis, Differential; D005260:Female; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color