Squamous cell carcinoma in vitiligo lesion after long-term PUVA therapy.
Photochemotherapy using psoralen and ultraviolet (UV)A irradiation (PUVA) is a useful treatment method for vitiligo. However, long-term PUVA therapy may cause several adverse effects including skin cancer, especially squamous cell carcinoma (SCC). We describe a case of SCC in vitiligo lesion after long-term PUVA therapy.
Park
H S
HS
Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, 761-1 Sanggye-7-Dong, Nowon-Gu, Seoul 139-707, Korea.
Lee
Y S
YS
Chun
D K
DK
D000328:Adult; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008134:Long-Term Care; D008297:Male; D011701:PUVA Therapy / Q000009:adverse effects* / Q000379:methods; D010413:Penis / Q000473:pathology*; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology; D014820:Vitiligo / Q000175:diagnosis / Q000188:drug therapy*