Spontaneous regression of congenital melanocytic nevi without evidence of the halo phenomenon.
Spontaneous regression of a congenital melanocytic nevus is rare and has always been thought to be associated with a halo phenomenon, suggesting that an immunological mechanism is involved in the regression process. We describe herein 2 cases of complete congenital melanocytic nevus regression without the halo phenomenon in 2 Japanese girls. To our knowledge, such a clinical progression has not been previously reported. We will also discuss several different possible mechanisms of regression.
Kageshita
Toshiro
T
Department of Dermatology, Kumamoto University School of Medicine, Kumamoto, Japan. toshiro@kaiju.medic.kumamoto-u.ac.jp
Inoue
Yuji
Y
Ono
Tomomichi
T
D002675:Child, Preschool; D005260:Female; D005385:Fingers; D006801:Humans; D007223:Infant; D009508:Nevus, Pigmented / Q000151:congenital* / Q000473:pathology; D012075:Remission, Spontaneous; D012878:Skin Neoplasms / Q000151:congenital* / Q000473:pathology