Palladium catalysed [2 + 2 + 1] intramolecular cycloaddition for the preparation of bicyclo[3.3.0]octa-1.5-dien-3-ones from 1,6-diynes.
Palladium catalysed [2 + 2 + 1] cycloaddition of 1,6-heptadiynes with CO (1 atm) furnishes bicyclo[3.3.0]octa-1,5-dien-3-ones in 30-74% yield.
Grigg
Ronald
R
Molecular Innovation, Diversity and Automated Synthesis Centre, School of Chemistry, Leeds University, Leeds, UK LS2 9JT. R.Grigg@chem.leeds.ac.uk
Zhang
Lixin
L
Collard
Simon
S
Keep
Ann
A