[A synthesis of dolichyl fluorophosphate].
An improved method for the synthesis of dolichyl H-phosphonate was developed using 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one (salicyl chlorophosphite) as a reagent. Dolichyl phosphorofluoridate was for the first time synthesized from dolichyl H-phosphonate by its treatment with chlorotrimethylsilane, oxidation with iodine, and subsequent interaction with fluoride ion in pyridine.
Sizova
O V
OV
Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninskii pr. 47, Moscow, 119991 Russia.
Mal'tsev
S D
SD
Shibaev
V N
VN
D004288:Dolichol Phosphates / Q000138:chemical synthesis* / Q000737:chemistry; D005461:Fluorine; D009682:Magnetic Resonance Spectroscopy
D004288:Dolichol Phosphates; D005461:Fluorine