Syntheses of the stereoisomers of neolignans morinol C and D.
Morinol C and morinol D are neolignans isolated from the Chinese medicinal herb Morina chinensis as racemates. (1R,2R)-Morinol C and (1S,2R)-morinol D were synthesized from (+)-(3R,4R)-4-(3,4-dimethoxyphenyl)-3-pivaloyloxymethyl-4-butanolide 4. On the other hand, (1S,2S)-morinol C and (1R,2S)-morinol D were synthesized from anti-aldol product 8.
Yamauchi
Satoshi
S
Department of Agriculture, Ehime University, Tarumi 3-5-7, Matsuyama, Ehime, 790-8566, Japan. syamauch@agr.ehime-u.ac.jp
Uno
Hidemitsu
H
D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D013057:Spectrum Analysis; D013237:Stereoisomerism
D017705:Lignans