title: A prospective multicenter study of the effect of patient education on acceptability of generic prescribing in general practice.
abstract: The purpose of the study was to assess patients' acceptability of the substitution of brand-name drugs for generic drugs in the primary health care prescribing practices for chronic conditions. A prospective randomised multicentre study was conducted over a 12-month period in which patients taking medications for chronic disorders received an educational intervention on generic drugs at the time they attended different general practices in the city of Barcelona (Spain) for repeat prescribing. Twenty-seven public primary care centres were randomised to the intervention group (eight centres) or the control group (19 centres). Of 4620 patients in the intervention group that received verbal information and handout materials on advantages and disadvantages of generic equivalents and brand-name drugs, 98.9% of them agreed to receive a generic formulation. The primary care centre and the class of drug were associated with statistically significant differences in the percentage of acceptance of generic drugs. In the overall population, generic prescribing in the intervention practices increased to 5.9 as compared with 2.8% in controls. In summary, individual educational intervention in patients with repeat prescribing resulted in a high rate of generic acceptability. The intervention might stimulate the practitioner's motivation, behaviour and knowledge of generic forms.
authors.affiliation: Servei d'Atenciò Primària Ciutat Vella, Institut Català de la Salut, Avinguda Drassanes 17-21, E-08001 Barcelona, Spain. javalles.pbcn@ics.scs.es
authors.forename: Joan Antoni
authors.initials: JA
authors.lastname: Vallès
authors.forename: Maica
authors.initials: M
authors.lastname: Barreiro
authors.forename: Glòria
authors.initials: G
authors.lastname: Cereza
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Ferro
authors.forename: María José
authors.initials: MJ
authors.lastname: Martínez
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Escribà
authors.forename: Begoña
authors.initials: B
authors.lastname: Iglesias
authors.forename: Esther
authors.initials: E
authors.lastname: Cucurull
authors.forename: Estrella
authors.initials: E
authors.lastname: Barceló
mesh_terms: D011307:Drug Prescriptions / Q000145:classification*; D016568:Drugs, Generic / Q000627:therapeutic use*; D005194:Family Practice / Q000706:statistics & numerical data*; D006302:Health Services Research; D006801:Humans; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D010353:Patient Education as Topic; D011320:Primary Health Care; D011446:Prospective Studies; D013030:Spain
chemical_list: D016568:Drugs, Generic