title: Dark chocolate inhibits platelet aggregation in healthy volunteers.
abstract: Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.
authors.affiliation: University Department of Medicine, Ninewells Hospital and Medical School, Dundee.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Innes
authors.forename: Gwen
authors.initials: G
authors.lastname: Kennedy
authors.forename: Margaret
authors.initials: M
authors.lastname: McLaren
authors.forename: Anne J
authors.initials: AJ
authors.lastname: Bancroft
authors.forename: Jill J F
authors.initials: JJ
authors.lastname: Belch
mesh_terms: D001792:Blood Platelets; D002099:Cacao; D002316:Cardiotonic Agents; D003094:Collagen; D006801:Humans; D015539:Platelet Activation; D010975:Platelet Aggregation Inhibitors; D010979:Platelet Function Tests
chemical_list: D002316:Cardiotonic Agents; D010975:Platelet Aggregation Inhibitors; D003094:Collagen