Malignant fibrous histiocytoma of the parotid gland.
Primary malignant fibrous histiocytoma (MFH) arising in a major salivary gland is rare. We encountered a case of MFH affecting the parotid gland. The patient was a 54-year-old man diagnosed as having pleomorphic type of MFH after extended total parotidectomy. Examination of the resected specimen revealed the tumor had not been completely removed. Accordingly treatment consisted in the resection of MFH and radiotherapy in combination with chemotherapy using carboplatin (CBDCA). This postoperative therapy was effective in controlling the growth of the remaining tumor tissue. As the patient showed no signs of local recurrence and distant metastasis for 5 years, plastic surgery was performed to improve the serious deformation of the face with a free anterolateral thigh flap. Our literature review yielded 17 cases of parotid MFH and the 2-year survival rate was 33%.
Kariya
Shin
S
Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. skariya@cc.okayama-u.ac.jp
Aoji
Katsuya
K
Kuyama
Kazushige
K
Akagi
Hirofumi
H
Fukazawa
Motoharu
M
Nishizaki
Kazunori
K
D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland; D018714:Radiotherapy, Adjuvant; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000628:therapy
D000970:Antineoplastic Agents