Imidazole alkaloids from Lepidium meyenii.
Two new imidazole alkaloids (lepidiline A and lepidiline B) have been isolated from a root extract of Lepidium meyenii with the common name Maca and identified as 1,3-dibenzyl-4,5-dimethylimidazolium chloride (1) and 1,3-dibenzyl-2,4,5-trimethylimidazolium chloride (2), respectively. The structures of these two new compounds were determined by spectroscopic methods, as well as single-crystal X-ray diffraction performed on compound 1.
Cui
Baoliang
B
PureWorld Botanicals, Inc., South Hackensack, New Jersey 07606, USA.
Zheng
Bo Lin
BL
He
Kan
K
Zheng
Qun Yi
QY
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007093:Imidazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029686:Lepidium / Q000737:chemistry*; D015394:Molecular Structure; D010568:Peru; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000470:Alkaloids; D007093:Imidazoles