title: History of depression and smoking cessation outcome: a meta-analysis.
abstract: The authors conducted a meta-analysis of published studies to (a) evaluate the premise that a history of major depression is associated with failure to quit smoking and (b) identify factors that moderate the relationship between history of depression and cessation outcome. Fifteen studies met the selection requirements and were coded for various study methodology and treatment characteristics. DSTAT was used to calculate individual study effect sizes, determine the mean effect size across studies, and test for moderator effects. No differences in either short-term (< or = 3 months) or long-term abstinence rates (> or = 6 months) were observed between smokers positive versus negative for history of depression. Lifetime history of major depression does not appear to be an independent risk factor for cessation failure in smoking cessation treatment.
authors.affiliation: Centers for Behavioral and Preventive Medicine, Brown Medical School/The Miriam Hospital, Providence, Rhode Island 02903, USA. brian_hitsman@brown.edu
authors.forename: Brian
authors.initials: B
authors.lastname: Hitsman
authors.forename: Belinda
authors.initials: B
authors.lastname: Borrelli
authors.forename: Dennis E
authors.initials: DE
authors.lastname: McChargue
authors.forename: Bonnie
authors.initials: B
authors.lastname: Spring
authors.forename: Raymond
authors.initials: R
authors.lastname: Niaura
mesh_terms: D000328:Adult; D003865:Major Depressive Disorder / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D016540:Smoking Cessation / Q000706:statistics & numerical data*; D014029:Tobacco Use Disorder / Q000150:complications* / Q000628:therapy*; D016896:Treatment Outcome