A dynamical model for the vertical vestibuloocular reflex and optokinetic response in primate.
The vestibuloocular reflex (VOR) in concert with the optokinetic response (OKR) stabilizes vision during head motion. The VOR system characteristics are both compensatory and adaptively self-calibrated. A model was constructed to aid in the understanding of the roles of the cerebellum and other neuronal sites in the performance and adaptation of the vertical VOR. The model structure was based upon the known neuroanatomy, and model parameters were estimated using experimental data. The model can reproduce and predict eye movements and cerebellar Purkinje cell firing patterns during VOR, OKR, and various visual-vestibular mismatch paradigms.
Hirata
Yutaka
Y
Department of Electronic Engineering, College of Engineering, Chubu University, Kasugai, Japan. yutaka@isc.chubu.ac.jp
Takeuchi
Ichiro
I
Highstein
Stephen M
SM
D000222:Adaptation, Physiological; D000818:Animals; D002531:Cerebellum / Q000502:physiology; D003198:Computer Simulation; D005133:Eye Movements; D019416:Head Movements; D008297:Male; D008959:Models, Neurological; D017120:Nystagmus, Optokinetic / Q000502:physiology*; D010775:Photic Stimulation; D011689:Purkinje Cells / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology*; D015203:Reproducibility of Results; D012453:Saimiri