2-aminothiazole and 2-aminothiazolinone derivatives.
The reaction of different substituted alpha-cyanooxiranes with thiourea resulted in the formation of the 2-aminothiazolinone derivative 2-amino-5-(2,5-dimethoxyphenyl)-1,3-thiazol-4(5H)-one, C(11)H(12)N(2)O(3)S, (I), and the 2-aminothiazole derivative ethyl 2-amino-5-(2,5-dimethoxyphenyl)-1,3-thiazole-4-carboxylate, C(14)H(16)N(2)O(4)S, (II). The geometries of the two crystallographically independent molecules in (II) are nearly identical but mirror related. The crystal structures of both compounds contain two types of intermolecular hydrogen bonds.
Toplak
Renata
R
Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia.
Lah
Nina
N
Volmajer
Julija
J
Leban
Ivan
I
Majcen Le Maréchal
Alenka
A
D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D015394:Molecular Structure; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry*
D013844:Thiazoles; C004483:2-aminothiazole