title: Metastatic sweat gland adenocarcinoma: A clinico-pathological dilemma.
abstract: BACKGROUND: Sweat gland adenocarcinoma is a rare malignancy with high metastatic potential seen more commonly in later years of life. Scalp is the most common site of occurrence and it usually spreads to lymph nodes. Liver, lung and bones are the distant sites of metastasis with fatal results. The differentiation between apocrine and eccrine metastatic sweat gland carcinoma is often difficult. The criteria's are inadequate to be of any practical utility. CASE REPORT: Two cases of metastatic sweat gland adenocarcinoma (one of eccrine and the other one of apocrine origin) are being reported on account of the rarity and different outcome. CONCLUSION: Sweat gland carcinomas are rare cancers with a poor prognosis often presenting as histological surprises. Surgery in the form of wide local excision and lymph node dissection is the mainstay of treatment. Chemotherapy and/or radiotherapy has limited role.
authors.affiliation: Department of Surgery, Vardhman Mahavir Medical College & Safdarjang Hospital, New Delhi 110023 India. chintamani7@rediffmail.com
authors.lastname: Chintamani
authors.forename: RD
authors.initials: R
authors.lastname: Sharma
authors.forename: Rohini
authors.initials: R
authors.lastname: Badran
authors.forename: Vinay
authors.initials: V
authors.lastname: Singhal
authors.forename: Sunita
authors.initials: S
authors.lastname: Saxena
authors.forename: Anju
authors.initials: A
authors.lastname: Bansal