title: New plasmid-borne antibiotic resistance gene cluster in Pasteurella multocida.
abstract: A new antibiotic resistance gene cluster comprising genes for sulfonamide (sul2), streptomycin (strA-strB), and tetracycline [tetR-tet(H)] resistance was detected on plasmid pVM111 from Pasteurella multocida. The tetR-tet(H) gene region was inserted between sul2 and strA, possibly by illegitimate recombination. Two potential recombination sites of 18 and 25 bp were identified.
authors.affiliation: Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), 31535 Neustadt-Mariensee, Germany.
authors.forename: Corinna
authors.initials: C
authors.lastname: Kehrenberg
authors.forename: Nga Thi Thu
authors.initials: NT
authors.lastname: Tham
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
mesh_terms: D001483:Base Sequence; D003001:Cloning, Molecular; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D016979:Pasteurella multocida / Q000187:drug effects* / Q000235:genetics*; D010957:Plasmids / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics; D015183:Restriction Mapping; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014169:Transformation, Bacterial / Q000235:genetics