title: Bancroftian filariasis in Nepal: a survey for circulating antigenemia of Wuchereria bancrofti and urinary IgG4 antibody in two rural areas of Nepal.
abstract: Serum and urine samples were randomly collected from residents in two rural areas at different altitudes in Nepal, and were examined for Wuchereria bancrofti antigens and antibodies (IgG4) to filarial antigens, respectively. In Judigaun, located at 900 m in altitude, 25.2% of 238 serum samples were positive for antigen, and 50.8% of 244 urine samples were positive for antibody. The level of IgG4 antibodies was higher among antigen positive individuals than among the antigen negatives. In Kotyang, located at 1100-1300 m, the prevalence of antigenemia was 15.4% of 117 serum samples.
authors.affiliation: Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, Sakamoto 1-12-4, Nagasaki 852-8523, Japan. kanji@net.nagasaki-u.ac.jp
authors.forename: Kanji
authors.initials: K
authors.lastname: Watanabe
authors.forename: Makoto
authors.initials: M
authors.lastname: Itoh
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuyama
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Hamano
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Taku
authors.initials: T
authors.lastname: Shirakawa
authors.forename: Akira
authors.initials: A
authors.lastname: Suzuki
authors.forename: Sashi
authors.initials: S
authors.lastname: Sharma
authors.forename: Gopal P
authors.initials: GP
authors.lastname: Acharya
authors.forename: Kazue
authors.initials: K
authors.lastname: Itoh
authors.forename: Terukazu
authors.initials: T
authors.lastname: Kawasaki
authors.forename: Eisaku
authors.initials: E
authors.lastname: Kimura
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Aoki
mesh_terms: D000328:Adult; D000947:Antigens, Helminth / Q000097:blood / Q000652:urine; D004605:Elephantiasis, Filarial / Q000453:epidemiology / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009390:Nepal / Q000453:epidemiology; D015995:Prevalence; D012424:Rural Population
chemical_list: D000947:Antigens, Helminth; D007074:Immunoglobulin G; C045193:Wuchereria antigen