title: Fly models of Huntington's disease.
abstract: Can Drosophila models be engineered that accurately reflect Huntington's disease (HD) and other neurological diseases and can they contribute to the search for treatments and cures? A number of publications seem to provide a resounding yes to that question. Here we seek to review some of the salient features of these models.
authors.affiliation: Department of Developmental and Cell Biology, University of California, Irvine, CA 92697-2300, USA. jlmarsh@uci.edu
authors.forename: J Lawrence
authors.initials: JL
authors.lastname: Marsh
authors.forename: Judit
authors.initials: J
authors.lastname: Pallos
authors.forename: Leslie M
authors.initials: LM
authors.lastname: Thompson
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004330:Drosophila; D006801:Humans; D006816:Huntington Disease / Q000378:metabolism / Q000503:physiopathology*