title: Validation of a volumic reconstruction in 4-d echocardiography and gated SPECT using a dynamic cardiac phantom.
abstract: A dynamic cardiac phantom was used as a reference to compare the volumes reconstructed with 4-D echocardiography and gated single-photon emission computed tomography (SPECT). 4-D echocardiography used a new prototype of rotating scan head to acquire ultrasound (US) images during a cardiac cycle, associated with a new protocol (left ventricular 4-D or LV 4-D) to reconstruct the volume deformations of the heart as a function of time. Gated SPECT data were acquired with a standard single-head gamma camera, and the reconstructions were carried out using the Mirage software released by Segami. The influences of different LV 4-D parameters were tested and analyzed. End-diastolic volume, end-systolic volume, and ejection fraction were measured using both LV 4-D and gated SPECT. Results obtained showed a straight correlation between the two examinations. The agreement confirmed the relevance of the comparisons. This study is an initial step before conducting clinical trials to exhaustively compare the two modalities.
authors.affiliation: Service de Cardiologie, Centre Hospitalier Régional d'Orléans, Orléans, France. Long-Dang.Nguyen@chr-orleans.fr
authors.forename: L D
authors.initials: LD
authors.lastname: Nguyen
authors.forename: C
authors.initials: C
authors.lastname: Léger
authors.forename: D
authors.initials: D
authors.lastname: Debrun
authors.forename: F
authors.initials: F
authors.lastname: Thérain
authors.forename: J
authors.initials: J
authors.lastname: Visser
authors.forename: E
authors.initials: E
authors.lastname: Busemann Sokole
mesh_terms: D019561:Echocardiography, Four-Dimensional / Q000379:methods*; D015637:Gated Blood-Pool Imaging / Q000379:methods; D006339:Heart Rate; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D006801:Humans; D015588:Observer Variation; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D013599:Systole; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods