Effectiveness of switching to quetiapine for neuroleptic-induced amenorrhea.
This study investigated the effectiveness and tolerability of a switching strategy using quetiapine in 16 women with schizophrenia who were suffering from haloperidol- or risperidone-induced amenorrhea. Findings revealed that 10 patients (71.6%) resumed menstruation, without worsening of psychotic symptoms.
Takahashi
Hitoshi
H
Department of Neurospsychiatry, Akita University School of Medicine, Honda, Akita City, Japan. hoto_takahashi@hotmail.com
Higuchi
Hisashi
H
Kamata
Mitsuhiro
M
Naitoh
Shingo
S
Yoshida
Keizo
K
Shimizu
Tetsuo
T
Sugita
Takio
T
D000328:Adult; D000568:Amenorrhea / Q000139:chemically induced / Q000188:drug therapy*; D000704:Analysis of Variance; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003987:Dibenzothiazepines / Q000627:therapeutic use*; D005260:Female; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D011388:Prolactin / Q000097:blood; D000069348:Quetiapine Fumarate; D020127:Recovery of Function; D018967:Risperidone / Q000009:adverse effects; D012559:Schizophrenia / Q000503:physiopathology; D013997:Time Factors
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D011388:Prolactin; D006220:Haloperidol; D018967:Risperidone