Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure.
We investigated the prevalence of anemia and its relation to clinical events in patients with decompensated heart failure enrolled in the OPTIME-CHF study. Our data demonstrate that anemia is common in patients hospitalized with decompensated heart failure and is associated with a greater number of co-morbid conditions. Lower baseline hemoglobin is associated with risk of short-term adverse clinical outcomes in this population, even after controlling for other baseline differences.
Felker
G Michael
GM
Duke Clinical Research Institute, Durham, North Carolina 27715, USA. felke001@mc.duke.edu
Gattis
Wendy A
WA
Leimberger
Jeffrey D
JD
Adams
Kirkwood F
KF
Cuffe
Michael S
MS
Gheorghiade
Mihai
M
O'Connor
Christopher M
CM
D000368:Aged; D000740:Anemia / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D002316:Cardiotonic Agents / Q000627:therapeutic use; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000150:complications* / Q000188:drug therapy / Q000401:mortality*; D006454:Hemoglobins / Q000032:analysis; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D020105:Milrinone / Q000627:therapeutic use; D015999:Multivariate Analysis; D010359:Patient Readmission / Q000706:statistics & numerical data*; D011237:Predictive Value of Tests; D015995:Prevalence; D011379:Prognosis; D016016:Proportional Hazards Models; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome
D002316:Cardiotonic Agents; D006454:Hemoglobins; D020105:Milrinone