title: Reductive cyclization of delta-hydroxy nitriles: a new synthesis of glycosylamines.
abstract: [reaction: see text] The stereoselective cyclization of delta-hydroxy nitriles to afford N,O-acetals and the application of this reaction toward the synthesis of glycosylamines is described.
authors.affiliation: Center for New Directions in Organic Synthesis, Department of Chemistry, University of California-Berkeley, Berkeley, California 94720, USA.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Dorsey
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Barbarow
authors.forename: Dirk
authors.initials: D
authors.lastname: Trauner
mesh_terms: D000080:Acetals / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D006020:Glycopeptides / Q000138:chemical synthesis; D006595:Hexosamines / Q000138:chemical synthesis*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000080:Acetals; D006020:Glycopeptides; D006595:Hexosamines; D009570:Nitriles