Enantioselective Rh-catalyzed hydrogenation of vinyl carboxylates with monodentate phosphite ligands.
[reaction: see text] Alkyl-substituted vinylcarboxylates, which normally show poor enantioselectivity in Rh-catalyzed hydrogenation with traditional chiral diphosphines, undergo highly enantioselective reactions with BINOL- and carbohydrate-based monophosphite ligands.
Reetz
Manfred T
MT
Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany. reetz@mpi-muelheim.mpg.de
Goossen
Lukas J
LJ
Meiswinkel
Andreas
A
Paetzold
Jens
J
Jensen
Jakob Feldthusen
JF