title: Pulmonary epithelioid hemangioendothelioma: a tumor presented as a single cavitary mass.
abstract: Pulmonary epithelioid hemangioendothelioma (PEH) is a rare tumor that occurs among young women and typically presents as bilateral multiple nodules. In the present report, we describe an uncommon case of PEH presented as a single cavitary nodule in a 33-yr-old asymptomatic man. This is the first case of PEH presented as a single cavitary nodule in the English literature. Three years of the follow-up without treatment was performed. Overall histologic findings were accord with conventional PEH, but some atypical features such as, increased mitotic activity (mean; two per ten high power fields), necrosis, spindling, and pleural and vascular invasion were recognized. Immunohistochemically, the tumor cells were positive for CD34. This report may contribute to the data on clinical findings and natural history of this rare tumor.
authors.affiliation: 5th Criminal Division, Daegu District Public Prosecutor's Office, Daegu, Korea.
authors.forename: Kyu Yun
authors.initials: KY
authors.lastname: Jang
authors.forename: Gong Yong
authors.initials: GY
authors.lastname: Jin
authors.forename: Yong Chul
authors.initials: YC
authors.lastname: Lee
authors.forename: Hung Bum
authors.initials: HB
authors.lastname: Lee
authors.forename: Myoung Jae
authors.initials: MJ
authors.lastname: Kang
authors.forename: Ho Yeul
authors.initials: HY
authors.lastname: Choi
authors.forename: Myoung Ja
authors.initials: MJ
authors.lastname: Chung
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000096:biosynthesis; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008938:Mitosis; D009336:Necrosis; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D018952:Antigens, CD34