In vitro effects of bipathic treatment with antibodies in ultralow doses during long-term post-tetanic potentiation.
We studied the effects of individual or combination treatment with monoclonal antibodies 5F5-B6 in ultralow doses specifically marking mossy fibers in rat hippocampus and antibodies to S100 protein during long-term post-tetanic potentiation in hippocampal slices. The possible mechanisms of changes produced by therapeutic administration of antibodies in ultralow doses were revealed.
Epstein
O I
OI
Materia Medica Holding Research-and-Production Company, Moscow.
Beregovoi
N A
NA
Pankova
T M
TM
Sorokina
N S
NS
Starostina
M V
MV
Shtark
M B
MB
D000818:Animals; D000906:Antibodies / Q000494:pharmacology*; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006624:Hippocampus / Q000187:drug effects* / Q000378:metabolism*; D066298:In Vitro Techniques; D017774:Long-Term Potentiation / Q000187:drug effects*; D051381:Rats; D009418:S100 Proteins / Q000276:immunology
D000906:Antibodies; D000911:Antibodies, Monoclonal; D009418:S100 Proteins