title: Monitoring of umbilical cord blood lead levels and sources assessment among the Inuit.
abstract: Analyses completed on samples collected between 1993 and 1996 showed that about 7% of 475 Inuit newborns from northern Quebec (Canada) had a cord blood lead concentration equal to or greater than 0.48 micromol/l, an intervention level adopted by many governmental agencies. A comparison between the cord blood lead isotope ratios of Inuit and southern Quebec newborns showed that lead sources for these populations were different. Our investigation suggests that lead shots used for game hunting were an important source of lead exposure in the Inuit population. A cohort study conducted in three Inuit communities shows a significant decrease of cord blood lead concentrations after a public health intervention to reduce the use of lead shot. Lead shot ammunition can be a major and preventable source of human exposure to lead.
authors.affiliation: Unité de recherche en santé publique, Centre de recherche du CHUL-CHUQ, 945, avenue Wolfe, Sainte-Foy, Québec G1V 5B3, Canada. Benoit.Levesque@crchul.ulaval.ca
authors.forename: B
authors.initials: B
authors.lastname: Lévesque
authors.forename: J-F
authors.initials: JF
authors.lastname: Duchesne
authors.forename: C
authors.initials: C
authors.lastname: Gariépy
authors.forename: M
authors.initials: M
authors.lastname: Rhainds
authors.forename: P
authors.initials: P
authors.lastname: Dumas
authors.forename: A M
authors.initials: AM
authors.lastname: Scheuhammer
authors.forename: J-F
authors.initials: JF
authors.lastname: Proulx
authors.forename: S
authors.initials: S
authors.lastname: Déry
authors.forename: G
authors.initials: G
authors.lastname: Muckle
authors.forename: F
authors.initials: F
authors.lastname: Dallaire
authors.forename: E
authors.initials: E
authors.lastname: Dewailly
mesh_terms: D015331:Cohort Studies; D004032:Diet / Q000009:adverse effects*; D004784:Environmental Monitoring / Q000379:methods; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005389:Firearms; D006801:Humans; D007231:Infant, Newborn; D004930:Inuit; D007854:Lead / Q000097:blood*; D015997:Neonatal Screening; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011792:Quebec
chemical_list: D007854:Lead