NMR-based screening technologies.
NMR-based ligand screening is now an established field in its own right. In recent years, advances in both methodology and hardware have broadened its range of applications and pushed back practical limitations, leading to the growing importance of NMR screening as a tool in industrial drug research. An overview of new screening methods and applications is presented here, and ways in which NMR-screening is being used in cooperation with other screening techniques are discussed.
Coles
Murray
M
Institut für Organische Chemie und Biochemie, Technische Universität München Lichtenbergstrasse 4, 85747, Garching, Germany.
Heller
Markus
M
Kessler
Horst
H
D016503:Drug Delivery Systems; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004345:Drug Industry; D008024:Ligands; D008279:Magnetic Resonance Imaging; D004364:Pharmaceutical Preparations / Q000737:chemistry
D008024:Ligands; D004364:Pharmaceutical Preparations