title: Lower extremity above-knee prosthesis-associated erectile dysfunction.
abstract: Blunt pelvic and perineal trauma has been previously reported to result in site-specific veno-occlusive dysfunction and/or site-specific cavernosal artery insufficiency. We herein describe a case of erectile dysfunction in a young previously potent amputee. We postulate that the erectile dysfunction is associated with a newly described form of blunt trauma, that is, site-specific compression from a perineal weight-bearing lower extremity above-knee prosthetic device. It is hypothesized that when the force exerted by the above-knee prosthesis is directed medially towards the ischiopubic ramus, the penile crura and common penile arterial blood supply become susceptible to crush-like injury, since they are in fixed anatomic locations in the perineum sandwiched between the compressive force and the bone. Clinical evaluation of the erectile dysfunction in this patient revealed site-specific corporal veno-occlusive dysfunction and site-specific common penile arterial occlusive pathology in the precise region of the contact of the above-knee prosthesis with the perineum. Further research is needed in above-knee prosthesis design to prevent erectile dysfunction.
authors.affiliation: Boston University School of Medicine, Department of Urology, Massachusetts, USA. munnarriz@bu.edu
authors.forename: R
authors.initials: R
authors.lastname: Munarriz
authors.forename: H
authors.initials: H
authors.lastname: Kulaksizoglu
authors.forename: L
authors.initials: L
authors.lastname: Hakim
authors.forename: S
authors.initials: S
authors.lastname: Gholami
authors.forename: A
authors.initials: A
authors.lastname: Nehra
authors.forename: I
authors.initials: I
authors.lastname: Goldstein
mesh_terms: D000328:Adult; D000674:Amputees; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D004867:Equipment Design; D007172:Erectile Dysfunction / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D010502:Perineum / Q000293:injuries; D014949:Wounds, Nonpenetrating / Q000209:etiology