title: Strategies to fit pattern-mixture models.
abstract: Whereas most models for incomplete longitudinal data are formulated within the selection model framework, pattern-mixture models have gained considerable interest in recent years (Little, 1993, 1994). In this paper, we outline several strategies to fit pattern-mixture models, including the so-called identifying restrictions strategy. Multiple imputation is used to apply this strategy to realistic settings, such as quality-of-life data from a longitudinal study on metastatic breast cancer patients.
authors.affiliation: Biostatistics, Center for Statistics, Limburgs Universitair Centrum, Universitaire Campus, B-3590 Diepenbeek, Belgium.
authors.forename: Herbert
authors.initials: H
authors.lastname: Thijs
authors.forename: Geert
authors.initials: G
authors.lastname: Molenberghs
authors.forename: Bart
authors.initials: B
authors.lastname: Michiels
authors.forename: Geert
authors.initials: G
authors.lastname: Verbeke
authors.forename: Desmond
authors.initials: D
authors.lastname: Curran