[Animal model study of guided bone tissue regeneration around implant by titanium membrane].
OBJECTIVE
To evaluate the titanium membrane-guided bone tissue regeneration around implant and HA granules.


METHODS
Three adult cross-bred dogs were used. In the animal's mandible, man-made bone damaged regions (diameter 6.5 mm, depth 4 mm) being concentric with the implant holes were prepared. The implants were planted into the holes and were rendered to separate the damaged regions into two parts with two titanium sheets. One part was filled with HA granules while the other with nothing. Histological evaluation was done at 4, 8 and 12 weeks of implantation.


RESULTS
The bone around the implants grew obviously at 4 weeks; the bone grew more and the structure of the bone was similar to that of the normal bone at 12 weeks.


CONCLUSIONS
As a new type of GTR materials, titanium membrane can keep the existence of spaces underneath. HA granules can give guiding effects to bone tissue regeneration.
Bao
Xiangjun
X
Department of Prosthetics, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Liang
Xing
X
Li
Xinghong
X
Gao
Weimin
W
D000818:Animals; D001861:Bone Regeneration; D004195:Disease Models, Animal; D004285:Dogs; D048091:Guided Tissue Regeneration; D006882:Hydroxyapatites; D008297:Male; D019736:Prostheses and Implants; D014025:Titanium
D006882:Hydroxyapatites; D014025:Titanium