title: Cryosurgical ablation of the prostate: current technique and clinical outcomes.
abstract: In addition to established therapies such as radiotherapy and radical prostatectomy, a number of newer therapies have been suggested to be effective in treating patients with clinically localized prostate carcinoma (PCA). One of these is cryoablation, a procedure that infarcts the prostate by the in situ application of percutaneous cryoprobes. Although results with this approach were mixed when introduced initially in 1993, recent improvements in technique and understanding of the mechanisms of cryo-injury in the prostate have led to renewed interest in this treatment option for patients with PCA.
authors.affiliation: Department of Urology, Tufts University School of Medicine and New England Medical Center Hospitals, Boston, Massachusetts, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Long
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D003452:Cryosurgery / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000032:analysis*; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D017430:Prostate-Specific Antigen