title: [Surgical strategy in oncologic diseases of organs of the pancreatobiliary zone complicated by mechanical jaundice].
abstract: In patients operated upon for oncological diseases of organs of the pancreatobiliary zone complicated by mechanical jaundice the lethality was decreased in a group of patients with purulent cholangitis and high biliary hypertension by means of using a two-stage method of operative treatment, use of the dosaged decompression of the bile ducts with a gradually increased diameter of the drain from 4 to 7-8 mm being most effective. A good effect of the application of complex antibacterial therapy was also noted when using a direct endolymphatic administration and intracholedochal perfusion of antibiotics. It allowed twice as quick to arrest the inflammatory process in the bile ducts, to normalize the biochemical indices of blood, and to prepare the patient for the main stage of operation.
authors.forename: I V
authors.initials: IV
authors.lastname: Iarema
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Popov
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Filippov
authors.forename: G G
authors.initials: GG
authors.lastname: Smirnov
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001650:Bile Duct Neoplasms / Q000150:complications / Q000601:surgery*; D017734:Bile Ducts, Extrahepatic; D002100:Cachexia / Q000150:complications; D002761:Cholangitis / Q000150:complications / Q000628:therapy; D003138:Common Bile Duct Neoplasms / Q000150:complications / Q000601:surgery*; D004322:Drainage; D005260:Female; D006801:Humans; D007272:Injections, Intralymphatic; D041781:Jaundice, Obstructive / Q000150:complications* / Q000628:therapy; D017093:Liver Failure / Q000150:complications; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents