An enantioselective double Diels-Alder approach to the tetracyclic framework of colombiasin A.
The complex tetracyclic carbon skeleton of colombiasin A is conveniently accessed through an enantioselective intermolecular Diels-Alder-sulfoxide elimination-intramolecular Diels-Alder (DA-E-IMDA) sequence.
Chaplin
Jason H
JH
Department of Chemistry, The Faculties, Australian National University, Canberra, ACT 0200, Australia.
Edwards
Alison J
AJ
Flynn
Bernard L
BL
D001952:Bridged-Ring Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D013454:Sulfoxides / Q000737:chemistry
D001952:Bridged-Ring Compounds; D013454:Sulfoxides; C408889:colombiasin A