Light absorption of (oxy-)hemoglobin assessed by spectroscopic optical coherence tomography.
The combination of optical coherence tomography and spectroscopy may allow for highly localized, quantitative measurements of tissue spectral properties. We present, for the first time to our knowledge, quantitative measurements of the absorption coefficients of phantoms and of hemoglobin and oxygenated hemoglobin with spectroscopic optical coherence tomography (SOCT). Our results suggest that SOCT will be able to provide localized, quantitative oxygenation measurements.
Faber
Dirk J
DJ
Laser Center, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands.
Mik
Egbert G
EG
Aalders
Maurice C G
MC
van Leeuwen
Ton G
TG
D000042:Absorption; D008027:Light; D008962:Models, Theoretical; D055095:Optics and Photonics; D010108:Oxyhemoglobins / Q000528:radiation effects*; D014054:Tomography
D010108:Oxyhemoglobins