A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives.
Bromination of an isolated double bond followed by aminocyclization furnishes a highly stereoselective protocol for the intramolecular formation of pyrrolidine and piperidine ring containing subunits that are presented in numerous biologically active natural products.
Shao
Zhihui
Z
School of Pharmacy, Yunnan University, Kunming, Yunnan 650091, PR China.
Chen
Jingbo
J
Tu
Yongqiang
Y
Li
Liang
L
Zhang
Hongbin
H