title: Incidence and circumstances of serum creatinine increase after abdominal aortic surgery.
abstract: OBJECTIVE
  To evaluate the incidence and the circumstances of a moderate increase in serum creatinine early after elective abdominal aortic surgery.
  
  
  METHODS
  Prospective clinical observational study.
  
  
  METHODS
  Surgical intensive care unit in a university hospital.
  
  
  METHODS
  Two hundred and fifteen consecutive adult patients operated on for infra-renal abdominal aortic surgery during 1 year.
  
  
  METHODS
  A moderate increase in plasma creatinine of 20% from preoperative value (renal dysfunction, RD) was systematically recorded during the first 3 days following surgery. Organ dysfunctions (cardiac, pulmonary, haematological, and neurological) were assessed.
  
  
  RESULTS
  Forty-three patients (20%) experienced a postoperative RD; six of these required dialysis. RD was associated with other organ dysfunctions in 60.5% patients. Mortality rate was significantly higher for patients who had a RD, than patients without RD (9.3% vs 1.2%, P<0.02). Mean ICU stay of patients with RD was significantly longer (7.9+/-5.6 days vs 5.0+/-1.8 days, P<0.01). However, patients with RD but without other organ dysfunctions had a mortality rate of 0% and did not have a significantly longer stay in ICU than patients without any organ dysfunctions (5.2+/-2.1 days vs 4.6+/-1.2 days, P=0.09).
  
  
  CONCLUSIONS
  Our results suggest that a postoperative 20%-increase in plasma creatinine after abdominal aortic surgery is not rare and occurs frequently with other organ dysfunction.
authors.affiliation: Department of Anesthesiology and Intensive Care, Hopital Arnaud de Villeneuve, avenue du Doyen Giraud, 34295 Montpellier, France. f-ryckwaert@chu-montpellier.fr
authors.forename: Frédérique
authors.initials: F
authors.lastname: Ryckwaert
authors.forename: Pierre
authors.initials: P
authors.lastname: Alric
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Picot
authors.forename: Kela
authors.initials: K
authors.lastname: Djoufelkit
authors.forename: Pascal
authors.initials: P
authors.lastname: Colson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001012:Aorta, Abdominal / Q000601:surgery*; D003404:Creatinine / Q000097:blood*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D051437:Renal Insufficiency / Q000097:blood* / Q000453:epidemiology / Q000209:etiology*; D014656:Vascular Surgical Procedures / Q000009:adverse effects*
chemical_list: D003404:Creatinine