Histopathologically proven poliomyelitis with quadriplegia and loss of brainstem function due to West Nile virus infection.
Recent electrophysiological and histopathological reports point to motor neurons in the anterior horn of the spinal cord and the brainstem as targets of severe West Nile virus (WNV) infection. We report histopathological confirmation of this poliomyelitis-like syndrome in a patient with WNV infection in Massachusetts.
Doron
Shira I
SI
Department of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Boston, MA, USA. sdoron@tufts-nemc.org
Dashe
John F
JF
Adelman
Lester S
LS
Brown
William F
WF
Werner
Barbara G
BG
Hadley
Susan
S
D000368:Aged; D001933:Brain Stem / Q000503:physiopathology* / Q000821:virology*; D006801:Humans; D008297:Male; D011051:Poliomyelitis / Q000821:virology*; D011782:Quadriplegia / Q000821:virology*; D014901:West Nile Fever / Q000821:virology*; D014902:West Nile virus / Q000302:isolation & purification