title: A-elute alleles of the ABO blood group system in Japanese.
abstract: The ABO blood group system is important in forensic genetics, as well as transfusion medicine. Since the elucidation of the molecular basis of ABO gene regulation, nucleotides of variant alleles or suballeles have been analyzed by polymerase chain reaction (PCR)-based methods and sequencing. Ael (A-elute) is one of the subgroups of A in the ABO system. By analyzing the suballeles responsible for Ael phenotype by PCR-RFLP and PCR direct sequencing, we found seven types of Ael allele. The allele frequency of ABO*Ael in a Japanese population was calculated to be 0.0049.
authors.affiliation: Department of Legal Medicine, Ehime University School of Medicine, Ehime 791-0295, Japan.
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Okiura
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Fukumori
authors.forename: Koji
authors.initials: K
authors.lastname: Nishimura
authors.forename: Chitoshi
authors.initials: C
authors.lastname: Orimoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Fujii
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nishimukai
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D005006:Ethnicity / Q000235:genetics*; D006801:Humans; D007564:Japan; D010641:Phenotype; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D000017:ABO Blood-Group System