title: Cutaneous angiosarcoma of the face.
abstract: Cutaneous angiosarcoma is a rare tumour of vascular origin, which has a poor prognosis because of its high potential for metastasis. We report the case of a 57-year-old man with an 8-month history of a progressively enlarging, asymptomatic red patch over the left periorbital region of the face, previously diagnosed as angiolupoid leishmaniasis, insect-bites, 'cellulitis' and treated with several topical antibiotic and steroid therapy, without any improvement. A skin biopsy of the lesion was performed and histological and immunohistochemical examination revealed a pattern of poorly differentiated angiosarcoma. The peculiarity of the localization at the periorbital area and the particular clinical presentation are emphasized.
authors.affiliation: Department of Territorial Social Medicine, Section of Dermatology, University of Messina, Italy. patrizia.cannavo@unime.it
authors.forename: S P
authors.initials: SP
authors.lastname: Cannavò
authors.forename: M
authors.initials: M
authors.lastname: Lentini
authors.forename: E
authors.initials: E
authors.lastname: Magliolo
authors.forename: C
authors.initials: C
authors.lastname: Guarneri
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D018450:Disease Progression; D005153:Facial Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*