[Issues related to atherosclerotic thrombosis in rheumatology].
Published data and independent author's information related with the mechanisms of development of atherosclerotic vascular lesions in inflammatory rheumatic diseases are under discussion in the article. A conclusion is made on a tense relationship between the atherosclerotic vascular lesions and thrombotic complications in systemic lupus erythematosus (SLE) and in rheumatoid arthritis (RA), on the one hand, and an impaired immunity system, which is a trigger for such diseases, on the other hand. A further study of this issue can be not only of an important theoretical but also of a big practical significance, which is related with designing new approaches towards prevention and treatment of atherosclerotic vascular lesions.
Nasonov
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D000328:Adult; D000367:Age Factors; D001161:Arteriosclerosis / Q000150:complications / Q000209:etiology*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000276:immunology; D016207:Cytokines / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012216:Rheumatic Diseases / Q000150:complications* / Q000276:immunology; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013927:Thrombosis / Q000150:complications / Q000209:etiology*
D016207:Cytokines; D008055:Lipids