Clinical and radiographic features of pulmonary tuberculosis in non-AIDS immunocompromised patients.
METHODS
Department of Chest Diseases, Istanbul Faculty of Medicine, Istanbul University.


OBJECTIVE
To determine the clinical and radiographic presentation of pulmonary tuberculosis in non-AIDS immunocompromised patients (ICP).


METHODS
A retrospective review of medical records of 143 patients (63 immunocompromised patients and 80 immunocompetent patients) with pulmonary tuberculosis from 1992 to 2001.


RESULTS
In ICPs, fever was more frequently observed (84.1% vs. 40%, P = 0.0000002), tuberculosis was more frequently disseminated (23.8 vs. 3.8%, P = 0.0008), and lung infiltrations were more often lobar or segmental consolidation (20.6% vs. 0%, P = 0.00007) and miliary lesions (17.5 vs. 3.8%, P = 0.014) than in the control patients. Hilar and/or mediastinal adenopathy was also more frequently documented in ICPs (14.3% vs. 2.5%, P = 0.01).


CONCLUSIONS
Fever, atypical chest radiograph and disseminated disease are common findings of pulmonary tuberculosis in ICPs.
Kiyan
E
E
Department of Pulmonary Diseases, Division of Nephrology, Istanbul Medical School, Istanbul University, Istanbul, Turkey. esenkiyan@turk.net
Kilicaslan
Z
Z
Gurgan
M
M
Tunaci
A
A
Yildiz
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000276:immunology
D007166:Immunosuppressive Agents