A zeolite-enzyme combination for biphasic dynamic kinetic resolution of benzylic alcohols.
Acid zeolites like H-Beta are efficient heterogeneous catalysts for racemization of benzylic alcohols in water; by combination of the racemization with an enzymatic kinetic resolution in a two-phase system, enantiomerically pure esters were obtained in high yield via a dynamic kinetic resolution.
Wuyts
Stijn
S
Centre for Surface Chemistry and Catalysis, KULeuven, Kasteelpark Arenberg 23, 3001 Leuven, Belgium.
De Temmerman
Karolien
K
De Vos
Dirk
D
Jacobs
Pierre
P
D001592:Benzyl Alcohols / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D004798:Enzymes / Q000737:chemistry*; D007700:Kinetics; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism; D017641:Zeolites / Q000737:chemistry*
D001592:Benzyl Alcohols; D004798:Enzymes; D012997:Solvents; D017641:Zeolites; C002017:methylphenyl carbinol