[Changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure].
OBJECTIVE
To investigate the changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure (CHF).


METHODS
The levels of serum TG, TC, HDL, and LDL in 36 patients with CHF and 20 healthy controls were measured and fatty acid cholesteryl esters were determined by high performance liquid chromatography.


RESULTS
In the patients with CHF, the level of linoleic acid was significantly higher than that in the control group (P < 0.05), but the level of arachidonic acid was significantly lower than that in the control group (P < 0.05). The levels of TC, TG, HDL, and LDL were not significantly different between the two groups.


CONCLUSIONS
Changes in fatty acid composition of serum cholesteryl esters exist in the patients with CHF.
Zhao
Yan-shu
YS
Department of Cardiology, Department of Clinical Laboratory, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhao
Shui-ping
SP
Tang
Ai-guo
AG
D000328:Adult; D000368:Aged; D016718:Arachidonic Acid / Q000097:blood; D002784:Cholesterol / Q000097:blood; D002788:Cholesterol Esters / Q000097:blood* / Q000737:chemistry; D002908:Chronic Disease; D005227:Fatty Acids / Q000097:blood / Q000737:chemistry*; D005260:Female; D006333:Heart Failure / Q000097:blood*; D006801:Humans; D019787:Linoleic Acid / Q000097:blood; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D002788:Cholesterol Esters; D005227:Fatty Acids; D014280:Triglycerides; D016718:Arachidonic Acid; D002784:Cholesterol; D019787:Linoleic Acid