Pulmonary epithelioid hemangioendothelioma: a tumor presented as a single cavitary mass.
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare tumor that occurs among young women and typically presents as bilateral multiple nodules. In the present report, we describe an uncommon case of PEH presented as a single cavitary nodule in a 33-yr-old asymptomatic man. This is the first case of PEH presented as a single cavitary nodule in the English literature. Three years of the follow-up without treatment was performed. Overall histologic findings were accord with conventional PEH, but some atypical features such as, increased mitotic activity (mean; two per ten high power fields), necrosis, spindling, and pleural and vascular invasion were recognized. Immunohistochemically, the tumor cells were positive for CD34. This report may contribute to the data on clinical findings and natural history of this rare tumor.
Jang
Kyu Yun
KY
5th Criminal Division, Daegu District Public Prosecutor's Office, Daegu, Korea.
Jin
Gong Yong
GY
Lee
Yong Chul
YC
Lee
Hung Bum
HB
Kang
Myoung Jae
MJ
Choi
Ho Yeul
HY
Chung
Myoung Ja
MJ
D000328:Adult; D018952:Antigens, CD34 / Q000096:biosynthesis; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008938:Mitosis; D009336:Necrosis; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D018952:Antigens, CD34