The "Malaria's Eve" hypothesis and the debate concerning the origin of the human malaria parasite Plasmodium falciparum.
The debate over whether the human malaria parasite Plasmodium falciparum underwent a recent severe population bottleneck ("Malaria's Eve" hypothesis) has attracted great attention recently. Understanding the genetic diversity and evolutionary history of the parasite has practical implications for developing disease control measures.
Su
Xin Zhuan
XZ
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA. xsu@niaid.nih.gov
Mu
Jianbing
J
Joy
Deirdre A
DA
D000818:Animals; D005075:Biological Evolution; D017125:Genes, Protozoan; D014644:Genetic Variation; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology; D010961:Plasmodium / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics* / Q000276:immunology