[Detection of serum sialic acid in three kinds of malignant tumor and its clinical significance].
OBJECTIVE
To study the diagnostic significance and clinical effect of the detection of serum sialic acid (SA) in three kinds of malignant tumor.


METHODS
The specimens (172) were divided into the healthy control group (100), lung cancer group (31), leukemia group (28) and rectual cancer group (17), and then the serum SA concentration in those specimens was analyzed and statistic analysis was conducted.


RESULTS
The SA levels of the malignant tumor groups before and after the treatment were significantly higher than those of the healthy control group (P < 0.05). The positive rates of serum SA in the lung cancer group, leukemia group and rectual group were 84%, 79% and 71%.


CONCLUSIONS
The SA concentration was significantly increased in the malignant patients so SA can be used as an indication of cancer, and it can be widely used in the diagnosis and inspection of malignant tumor.
Liang
Xiang-hui
XH
Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008, China.
Liang
Xian-ming
XM
Yi
Bin
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D007938:Leukemia / Q000097:blood*; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000097:blood*; D012794:Sialic Acids / Q000097:blood*
D014408:Biomarkers, Tumor; D012794:Sialic Acids