Internal chirality transfer in the reaction of substituted cyclic (S,O)-ketene ortho esters with aldehydes catalysed by Lewis acid.
Internal chirality transfer of 1a and 1b with aldehydes in the presence of Lewis acid catalyst resulted in high diastereoselectivities in the construction of a highly functionalised acyclic system.
Yu
Chan-Mo
CM
Department of Chemistry and Lab for Metal-Catalyzed Reactions (NRL), Sungkyunkwan University, Suwon 440-746, Korea. cmyu@chem.skku.ac.kr
Lee
Junhee
J
Kim
Ji-Min
JM
Lee
Su-Kyung
SK