A convenient method for the preparation of inverted tert-alkyl carboxylates from chiral tert-alcohols by a new type of oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone.
Oxidation-reduction condensation using in situ-formed alkoxydiphenylphosphines, 2,6-dimethyl-1,4-benzoquinone, and carboxylic acids provided a new and efficient method for the preparation of inverted tert-alkyl carboxylates from various chiral tertiary alcohols.
Mukaiyama
Teruaki
T
Center for Basic Research, The Kitasato Institute, 6-15-5 Toshima, Kita-ku, Tokyo 114-0003, Japan. Mukaiyam@abeam.ocn.ne.jp
Shintou
Taichi
T
Fukumoto
Kentaro
K