Intrauterine pregnancy following transperitoneal oocyte and/or sperm migration in a woman with an ectopic (undescended) ovary.
This is the first report of an intrauterine pregnancy following timed coitus, resulting from transperitoneal sperm and/or oocyte migration as the oocyte originated from an ectopic (undescended) ovary. The patient was treated in the infertility clinic after a history of primary infertility for 2 years. Diagnosis of a moderate teratozoospermia and the presence of a unicornuate uterus with one right-sided normal ovary was made. During the first intrauterine insemination (IUI) treatment cycle with clomiphene citrate stimulation, a discrepancy between oestradiol concentrations and follicular growth was observed. Magnetic resonance imaging (MRI) was carried out because the presence of an ectopic ovary was suspected. The diagnosis of a left-sided undescended ovary was made, containing several follicles, the largest measuring 16 mm in diameter. Because of a spontaneous LH surge 2 days later without substantial follicular growth in the normal right-sided ovary, IUI was cancelled and timed intercourse was planned. Surprisingly, and although the largest follicle in the normally located ovary reached a maximum diameter of only 12 mm on repetitive ultrasound monitoring, this patient became pregnant and gave birth to a healthy baby boy.
Ombelet
Willem
W
Department of Obstetrics and Gynecology, Ziekenhuizen Oost-Limburg, Schiepse Bos 6, 3600 Genk, Belgium. willem.ombelet@pandora.be
Deblaere
Karen
K
Grieten
Martin
M
Verswijvel
Geert
G
Nijs
Martine
M
Hinoul
Piet
P
de Jonge
Eric
E
D000328:Adult; D002996:Clomiphene / Q000494:pharmacology; D004958:Estradiol / Q000378:metabolism; D005187:Fallopian Tubes / Q000473:pathology; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D007986:Luteinizing Hormone / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D009865:Oocytes / Q000378:metabolism*; D010053:Ovary / Q000378:metabolism / Q000473:pathology; D010060:Ovulation; D010062:Ovulation Induction; D011247:Pregnancy; D013081:Sperm Motility; D013997:Time Factors; D014599:Uterus / Q000473:pathology
D002996:Clomiphene; D004958:Estradiol; D007986:Luteinizing Hormone