title: Nitration of 2'-deoxyguanosine by a NO/O2 gas mixture: identification and characterization of N2-nitro-2'-deoxyguanosine.
abstract: [reaction: see text] A gas mixture of NO and O(2) was bubbled into 2'-deoxyguanosine solution at neutral pH and 37 degrees C. A novel nitrated nucleoside was generated in the reaction mixture in addition to 8-nitroguanine, 8-nitroxanthine, 2'-deoxyxanthosine, xanthine, and guanine. The novel nucleoside was identified as N(2)-nitro-2'-deoxyguanosine by spectrometric data.
authors.affiliation: Institute of Advanced Energy, Kyoto University, Uji 611-0011, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Yamada
authors.forename: Toshinori
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kenji
authors.initials: K
authors.lastname: Kanaori
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Tajima
authors.forename: Shunji
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Kodaki
authors.forename: Keisuke
authors.initials: K
authors.lastname: Makino
mesh_terms: D003849:Deoxyguanosine / Q000031:analogs & derivatives*; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009566:Nitrates / Q000737:chemistry*; D009569:Nitric Oxide; D009705:Nucleosides / Q000737:chemistry; D010100:Oxygen; D019820:Xanthine / Q000737:chemistry; D014970:Xanthines / Q000737:chemistry
chemical_list: C432525:8-Nitroxanthine; C095838:8-nitroguanine; D009566:Nitrates; D009705:Nucleosides; D014970:Xanthines; D019820:Xanthine; D009569:Nitric Oxide; D006147:Guanine; D003849:Deoxyguanosine; D010100:Oxygen