title: Myxoid liposarcoma confirmed by TLS/FUS-CHOP fusion transcripts.
abstract: Described here is the use of detecting TLS/FUS-CHOP fusion transcripts to confirm the diagnosis of a myxoid liposarcoma by nested reverse transcription-polymerase chain reaction assay using archival formalin-fixed, paraffin-embedded tissues of a young man with a benign-looking myxoid tumor on his upper extremity, which is often misdiagnosed clinically or histopathologically as a benign tumor.
authors.affiliation: Department of Dermatology, Chang Gung Memorial Hospital, 199 Tung-Hwa North Road, Taipei 105, Taiwan.
authors.forename: Yau-Li
authors.initials: YL
authors.lastname: Huang
authors.forename: Hong-Shang
authors.initials: HS
authors.lastname: Hong
authors.forename: Tseng-Tong
authors.initials: TT
authors.lastname: Kuo
authors.forename: Chi-Jung
authors.initials: CJ
authors.lastname: Chung
mesh_terms: D000328:Adult; D017398:Alternative Splicing / Q000235:genetics*; D001132:Arm; D022762:CCAAT-Enhancer-Binding Proteins / Q000235:genetics*; D006801:Humans; D018208:Liposarcoma, Myxoid / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D012334:RNA, Neoplasm / Q000235:genetics*; D034702:RNA-Binding Protein FUS / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000235:genetics*; D051742:Transcription Factor CHOP
chemical_list: D022762:CCAAT-Enhancer-Binding Proteins; D015514:Oncogene Proteins, Fusion; D012334:RNA, Neoplasm; D034702:RNA-Binding Protein FUS; C106030:TLS-CHOP fusion protein, human; D051742:Transcription Factor CHOP