title: Luminescent nonacoordinate cationic lanthanide complexes as potential cellular imaging and reactive probes.
abstract: Nonacoordinate delta- and lambda-Eu and Tb complexes have been tested as imaging and reactive probes in mouse fibroblast (NIH 3T3) cells. The uptake of these complexes by the cells was assessed by fluorescence microscopy. Complex-induced DNA damage was studied by gel electrophoresis and shown to be a function of complex chirality.
authors.affiliation: Department of Chemistry, University of Durham, South Road, Durham, UK DH1 3LE.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Frias
authors.forename: Gabriella
authors.initials: G
authors.lastname: Bobba
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Cann
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Hutchison
authors.forename: David
authors.initials: D
authors.lastname: Parker
mesh_terms: D016475:3T3 Cells; D000818:Animals; D002412:Cations; D005456:Fluorescent Dyes / Q000493:pharmacokinetics; D028581:Lanthanoid Series Elements; D051379:Mice; D008856:Microscopy, Fluorescence; D009942:Organometallic Compounds / Q000493:pharmacokinetics
chemical_list: D002412:Cations; D005456:Fluorescent Dyes; D028581:Lanthanoid Series Elements; D009942:Organometallic Compounds