[Functional results and quality of life after proctocolectomy and ileal J-pouch-anal anastomosis for ulcerative colitis].
BACKGROUND
Ileal pouch-anal anastomosis is the surgical standard in the therapy of ulcerative colitis. It was the aim of the present study to evaluate functional long-term results and correlate them with quality of life.


METHODS
37 patients with a follow-up of more than 5 years were included. Functional results and quality of life were assessed by standardised questionnaires (modified Kelly-Hohlschneider-Score, EORTC QLQ-C30).


RESULTS
24 of 37 patients could be evaluated. Median follow-up was 8 (5-13) years. Postoperative stool- frequency was 5.5 +/- 1.7/d. When compared with the preoperative situation, patients suffered less from urgency. Stool-frequency and -consistency, soiling and sensibility remained unchanged. 83 % of patients had a subjective increase of life quality with the ileoanal pouch. The quality of life index was almost normal with 83 (28-100) %. Patients with postoperative complications had a significant decrease of life quality when compared to patients with uneventful course. There was no statistically significant correlation of life quality with age, gender or stool continence.


CONCLUSIONS
Ileal pouch-anal anastomosis leads to a long-term increase of stool frequency with partially impaired stool continence. Patients with uneventful course have a significantly better life quality.
Willis
S
S
Chirurgische Universitätsklinik und Poliklinik der RWTH Aachen. swillis@ukaachen.de
Lörken
M
M
Hölzl
F
F
Fackeldey
V
V
Schumpelick
V
V
D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000601:surgery*; D039021:Colonic Pouches; D003627:Data Interpretation, Statistical; D005242:Fecal Incontinence / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors