Acute cardiac failure in neuroleptic malignant syndrome.
We present a case of rapid onset acute cardiac failure developing as part of neuroleptic malignant syndrome in a 35-year-old woman following treatment with thioridazine and lithium. Post mortem histology of cardiac and skeletal muscle showed similar changes of focal cellular necrosis and vacuolation suggesting a common disease process.
Sparrow
Patrick
P
Department of Cardiology, Cork University Hospital, Cork, Ireland. patsparrow@doctors.net.uk
Murnaghan
Dermot
D
Kearney
Peter
P
Hogan
John
J
Sheppard
Mary N
MN
D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000209:etiology / Q000473:pathology*; D006801:Humans; D032342:Muscle Cells / Q000473:pathology; D018482:Muscle, Skeletal / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D009336:Necrosis; D009459:Neuroleptic Malignant Syndrome / Q000150:complications / Q000473:pathology*