title: [First human transcatheter implantation of an aortic valve prosthesis in a case of severe calcific aortic stenosis].
abstract: A percutaneous implantable prosthetic heart valve was developed, and after animal studies, the first human case was performed in a 57-year-old man with calcific aortic stenosis with cardiogenic shock. The implantation was performed with the use of an antegrade trans-septal approach after aortic valvuloplasty, and over a follow-up period of 4 months, the valvular function remained satisfactory. However, severe noncardiac complications occurred leading to death 17 weeks after implantation.
authors.affiliation: Service de cardiologie, hôpital Charles-Nicolle, 1, rue de Germont, 76000, Rouen, France. alain.cribier@chu-rouen.fr
authors.forename: A
authors.initials: A
authors.lastname: Cribier
authors.forename: H
authors.initials: H
authors.lastname: Eltchaninoff
authors.forename: C
authors.initials: C
authors.lastname: Tron
mesh_terms: D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000601:surgery*; D002114:Calcinosis; D006328:Cardiac Catheterization; D002404:Catheterization; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors