title: Biosynthesis of epothilone intermediates with alternate starter units: engineering polyketide-nonribosomal interfaces.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: O'Connor
authors.forename: Christopher T
authors.initials: CT
authors.lastname: Walsh
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry*; D001665:Binding Sites; D034261:Epothilones / Q000096:biosynthesis* / Q000737:chemistry; D005818:Genetic Engineering; D018942:Macrolides / Q000737:chemistry; D008969:Molecular Sequence Data; D010453:Peptide Synthases / Q000737:chemistry / Q000378:metabolism; D020836:Protein Structure, Quaternary
chemical_list: D000970:Antineoplastic Agents; D034261:Epothilones; D018942:Macrolides; D010453:Peptide Synthases; C104385:non-ribosomal peptide synthase