title: Potentiated antibodies against morphine: effects on biogenic amines and lipid peroxidation in chronically morphinized rats.
abstract: The efficiency of potentiated antibodies against morphine was studied on the model of chronic morphine intoxication. Test antibodies stimulated catecholamine metabolism in the hypothalamus (i.e., prevented initiation of catecholamine- and histaminergic peripheral reactions) and normalized lipid peroxidation.
authors.affiliation: Institute of Neurology, Psychiatry, and Narcology, Ukrainian Academy of Medical Sciences, Kharkov.
authors.forename: A M
authors.initials: AM
authors.lastname: Titkova
authors.forename: S M
authors.initials: SM
authors.lastname: Kharitonova
authors.forename: I R
authors.initials: IR
authors.lastname: Pan
authors.forename: O I
authors.initials: OI
authors.lastname: Epstein
mesh_terms: D000818:Animals; D000906:Antibodies / Q000494:pharmacology*; D001679:Biogenic Amines / Q000378:metabolism*; D002395:Catecholamines / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D009020:Morphine / Q000037:antagonists & inhibitors* / Q000276:immunology; D009021:Morphine Dependence; D051381:Rats
chemical_list: D000906:Antibodies; D001679:Biogenic Amines; D002395:Catecholamines; D009020:Morphine