[Study on the surface-enhanced Raman spectrum of trimethoprim].
A new method is given in this paper to study the spectra of trimethoprim by using the surface-enhanced Raman spectrum (SERS) technology and the highly efficient thin layer chromatography (TLC) dissociation technology. The results of SERS indicate that the main vibrant spectral band can be obtained by TLC in the samples of about 6 micrograms. The expansion and contraction of pyrimidine ring can be obviously increased and the molecule information can be exactly presented under the action of silver particles.
Zhang
Jin-zhi
JZ
North University of Technology, Beijing 100041, China.
Wang
Yuan
Y
D002855:Chromatography, Thin Layer / Q000379:methods; D005583:Fourier Analysis; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods; D014295:Trimethoprim / Q000737:chemistry*
D011743:Pyrimidines; D012834:Silver; D014295:Trimethoprim