title: The reality of treating dyslipidaemia in patients with coronary heart disease: a primary care survey.
abstract: Management of hyperlipidaemia in patients with ischaemic heart disease is suboptimal despite the proven benefit of statin therapy. Significant improvement in management has been shown in the EUROASPIRE II study. It is unclear, however, whether such changes have also occurred in primary care. We aimed to evaluate the use of statin therapy by performing a cross-sectional survey of 300 patients with CHD aged >30 years from three general practices. A total of 249 (83%) of the 300 patients had their cholesterol measured and 141 (47%) were on statin therapy; 129 (43% of total) achieved a target cholesterol of <5 mmol/l, of whom 85 (64%) were on statin therapy. Of the remaining 120 patients whose cholesterol exceeded 5 mmol/l, 56 (47%) were on statin therapy Thus 60% (85/141) of those on statin therapy achieved adequate control compared with 40% (44/108) without statins (p<0.008). Those patients with CHD diagnosed on objective evidence were more likely to receive statin therapy (55.5%). Many patients with CHD are still not receiving appropriate secondary prevention. Those on statin therapy are more likely to achieve target levels <5 mmol/l. The average doses of statins vary and are lower than the evidence-based doses used in previous large-scale studies, which may help explain the persistence of failed treatment.
authors.affiliation: Cardiothoracic Centre, Liverpool, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Wright
authors.forename: A D
authors.initials: AD
authors.lastname: Grayson
authors.forename: M
authors.initials: M
authors.lastname: Jackson
authors.forename: C
authors.initials: C
authors.lastname: Dainty
mesh_terms: D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D015331:Cohort Studies; D003327:Coronary Disease / Q000150:complications / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male
chemical_list: D000924:Anticholesteremic Agents; D000960:Hypolipidemic Agents