Post-transcriptional gene silencing in plants by RNA.
RNA silencing, which is termed post-transcriptional gene silencing in plants, is an RNA degradation process through sequence-specific nucleotide interactions induced by double-stranded RNA. In plants, RNA silencing not only serves as a component of the defense mechanism, but also participates in the regulation of endogenous gene expression in a variety of developmental processes. This review elaborates the current progress on the understanding of the molecular basis of RNA silencing including a mechanistic link between the regulation of microRNA and RNA silencing. The practical use of RNA silencing as a reverse genetics approach in plant functional genomics is also discussed.
Yu
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Department of Biological Sciences, Faculty of Science, National University of Singapore, 10 Science Drive 4, 117543 Singapore, Singapore.
Kumar
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PP
D020868:Gene Silencing; D018745:Genome, Plant; D010944:Plants / Q000235:genetics*; D012323:RNA Processing, Post-Transcriptional / Q000235:genetics*; D012330:RNA, Double-Stranded / Q000235:genetics; D018749:RNA, Plant / Q000235:genetics*
D012330:RNA, Double-Stranded; D018749:RNA, Plant