The genetics of gene expression and gene mapping.
A recent publication has shown that a significant portion of gene expression levels are under genetic control in different organisms, that there are hotspot regions in the genome that control the expression of many other genes, and how gene expression data can be used to localize genes that affect clinical traits.
Kraft
Peter
P
Department of Biostatistics, UCLA School of Public Health, Box 951772 51-236C CHS, Los Angeles, CA 90095-1772, USA.
Horvath
Steve
S
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D002874:Chromosome Mapping; D005786:Gene Expression Regulation / Q000235:genetics*; D018740:Genetic Heterogeneity; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*