title: Non-covalent stabilization of a beta-hairpin peptide into liposomes.
abstract: An oligopeptide modified on both the N- and C-termini with hydrophobic moieties was prepared on a solid phase and anchored into a liposome, stabilizing the fold of the peptide into a beta-hairpin, which would otherwise be a random coil.
authors.affiliation: Department of Organic Chemistry University of Nijmegen, Toernooiveld 1-U177, 6525 ED Nijmegen, The Netherlands. lowik@sci.kun.nl
authors.forename: Dennis W P M
authors.initials: DW
authors.lastname: Löwik
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Linhardt
authors.forename: P J Hans M
authors.initials: PJ
authors.lastname: Adams
authors.forename: Jan C M
authors.initials: JC
authors.lastname: van Hest
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002942:Circular Dichroism; D008081:Liposomes / Q000737:chemistry*; D008958:Models, Molecular; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry; D010963:Plasmodium falciparum; D011312:Pressure; D017433:Protein Structure, Secondary; D015800:Protozoan Proteins / Q000235:genetics
chemical_list: D008081:Liposomes; D009842:Oligopeptides; D010713:Phosphatidylcholines; D015800:Protozoan Proteins