title: Photosensitized DNA cleavage promoted by amino acids.
abstract: A novel class of DNA cleavage agents are reported that derive activity from amino acids tethered to a photoactive intercalator.
authors.affiliation: Boston College, Eugene F. Merkert Chemistry Center, Chestnut Hill, MA 02467, USA.
authors.forename: Kerry P
authors.initials: KP
authors.lastname: Mahon
authors.forename: Rodrigo F
authors.initials: RF
authors.lastname: Ortiz-Meoz
authors.forename: Erin G
authors.initials: EG
authors.lastname: Prestwich
authors.forename: Shana O
authors.initials: SO
authors.lastname: Kelley
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000494:pharmacology*; D052160:Benzothiazoles; D004247:DNA / Q000737:chemistry / Q000187:drug effects* / Q000528:radiation effects; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000235:genetics; D005456:Fluorescent Dyes / Q000737:chemistry; D015394:Molecular Structure; D017319:Photosensitizing Agents / Q000737:chemistry / Q000494:pharmacology*; D010957:Plasmids / Q000737:chemistry / Q000187:drug effects / Q000528:radiation effects; D011804:Quinolines; D013844:Thiazoles / Q000737:chemistry; D013997:Time Factors
chemical_list: D000596:Amino Acids; D052160:Benzothiazoles; D005456:Fluorescent Dyes; D017319:Photosensitizing Agents; D011804:Quinolines; D013844:Thiazoles; C051000:thiazole orange; D004247:DNA