title: [Sequence analysis and genetic polymorphisms of D4S1647 and D6S2414 loci in Chinese Han, Mongolian and Tibetan populations].
abstract: OBJECTIVE
  To investigate the polymorphisms of two short tandem repeats (STR) loci D4S1647 and D6S2414 in Chinese Han, Mongolian and Tibetan populations.
  
  
  METHODS
  Blood and saliva samples were collected from 308 unrelated individuals in the three populations. DNA was extracted by chelex-100 method and amplified by the polymerase chain reaction (PCR). The PCR products were analyzed by nondenaturing polyacrylamide gel electrophoresis and silver staining.
  
  
  RESULTS
  The genotype distributions of D4S1647 and D6S2414 loci were in accordance with Hardy-Weinberg equilibrium. The frequencies of alleles showed no significant differences among the three populations. Analyses of Han families indicated that the alleles agreed with Mendelian inheritance law.
  
  
  CONCLUSIONS
  This study yielded information on the genetic polymorphisms of the two STR loci in Chinese Han, Mongolian and Tibetan populations.
authors.affiliation: Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Tang
authors.forename: Miao
authors.initials: M
authors.lastname: Liao
authors.forename: Yu
authors.initials: Y
authors.lastname: Hu
authors.forename: Weibo
authors.initials: W
authors.lastname: Liang
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Guodi
authors.initials: G
authors.lastname: Chen
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics; D002681:China / Q000208:ethnology; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D020080:Tandem Repeat Sequences / Q000235:genetics*