Xanthones and benzophenones from the stems of Garcinia multiflora.
Two new xanthone derivatives, garcinianones A (1) and B (2), two new benzophenone derivatives, 4,6,4'-trihydroxy-2,3'-dimethoxy-3-prenylbenzophenone (3) and 4,6,3',4'-tetrahydroxy-2-methoxybenzophenone (4), and a new inseparable mixture of (1E,22Z)-1,22-diferuloyloxydocosane and (1E,24Z)-1,24-diferuloyloxyteracosane (5), together with the previously known 3,8-dihydroxy-2,4,6-trimethoxyxanthone, 6,3'-dihydroxy-2,4-dimethoxybenzophenone, maclurin (6), 2,4,6,3'-tetrahydroxybenzophenone (7), and naringenin, were isolated from the stems of Garcinia multiflora. The structures of 1-5 were elucidated by extensive analysis of their spectral data. Compounds were evaluated in the brine shrimp lethality test and in the DPPH antioxidant assay.
Chiang
Yi-Ming
YM
Department of Chemistry, National Taiwan University, Taipei, Taiwan, Republic of China.
Kuo
Yueh-Hsiung
YH
Oota
Shyuzo
S
Fukuyama
Yoshiyasu
Y
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects*; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds; D029760:Garcinia / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D013237:Stereoisomerism; D013624:Taiwan; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C479812:4,6,3',4'-tetrahydroxy-2-methoxybenzophenone; C479811:4,6,4'-trihydroxy-2,3'-dimethoxy-3-prenylbenzophenone; D000975:Antioxidants; D001577:Benzophenones; D001713:Biphenyl Compounds; D010851:Picrates; D044004:Xanthones; C479809:garcinianone A; C479810:garcinianone B; C004931:1,1-diphenyl-2-picrylhydrazyl