title: [Quantitative analysis of rutin and vitamin C by NIR FTIR].
abstract: In this paper, near-infrared diffuse reflectance spectroscopy(NIRDRS) method was used as a quantitative tool to measure the solid mixture of rutin and vitamin C by collecting NIR spectra in the range 7,000-3,900 cm-1. The quantitative mathematics model was established with partial least squares(PLS) method. The correlation coefficient was 99.75%, the standard error of Rutin was 0.363%, and the standard error of Vitamin C was 1.078%. The methods are rapid, exact and nondestructive to samples. The components of the samples can be individually analyzed with high accuracy and precision, so NIRDRS can be a useful method of quality control of pharmaceuticals in the future.
authors.affiliation: Department of Chemistry, Tsinghua University, 100084 Beijing.
authors.forename: D
authors.initials: D
authors.lastname: Du
authors.forename: S
authors.initials: S
authors.lastname: Sun
authors.forename: Q
authors.initials: Q
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Liang
authors.forename: X
authors.initials: X
authors.lastname: Yang
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis*; D004366:Nonprescription Drugs / Q000737:chemistry; D012431:Rutin / Q000032:analysis*; D017550:Spectroscopy, Fourier Transform Infrared; D019265:Spectroscopy, Near-Infrared
chemical_list: D004366:Nonprescription Drugs; D012431:Rutin; D001205:Ascorbic Acid