title: [Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
abstract: Principal component regression (PCR) method is used to analyse five components: acetaminophen, p-aminophenol, caffeine, chlorphenamine maleate and guaifenesin. The basic principle and the analytical step of the approach are described in detail. The computer program of LHG is based on VB language. The experimental result shows that the PCR method has no systematical error as compared to classical method. The experimental result shows that the average recovery of each component is all in the range from 96.43% to 107.14%. Each component obtains satisfactory result without any pre-separation. The approach is simple, rapid and suitable for the computer-aid analysis.
authors.affiliation: Department of Biological and Chemistry Engineering, Zhejiang University of Science and Technology, Hangzhou 310012, China.
authors.forename: Li-qing
authors.initials: LQ
authors.lastname: Zhang
authors.forename: Xiao-hua
authors.initials: XH
authors.lastname: Wu
authors.forename: Xi
authors.initials: X
authors.lastname: Tang
authors.forename: Xian-liang
authors.initials: XL
authors.lastname: Zhu
authors.forename: Wen-ting
authors.initials: WT
authors.lastname: Su
mesh_terms: D000082:Acetaminophen / Q000032:analysis*; D000627:Aminophenols / Q000032:analysis*; D018712:Analgesics, Non-Narcotic / Q000032:analysis*; D002110:Caffeine / Q000032:analysis*; D002744:Chlorpheniramine / Q000032:analysis; D004338:Drug Combinations; D005100:Expectorants / Q000032:analysis; D006140:Guaifenesin / Q000032:analysis; D006634:Histamine H1 Antagonists / Q000032:analysis; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
chemical_list: D000627:Aminophenols; D018712:Analgesics, Non-Narcotic; D004338:Drug Combinations; D005100:Expectorants; D006634:Histamine H1 Antagonists; D000082:Acetaminophen; D002110:Caffeine; D002744:Chlorpheniramine; D006140:Guaifenesin; C026729:4-aminophenol