[Role of kaliuretic peptide and molar ratio of kaliuretic peptide/atrial natriuretic peptide in atrial fibrillation].
OBJECTIVE
To investigate the role of kaliuretic peptide (KP) and molar ratio of KP/ atrial natriuretic peptide (ANP) in atrial fibrillation.


METHODS
The levels of plasma KP and ANP in 23 patients with paroxysmal atrial fibrillation (group I), 24 patients with persistent atrial fibrillation (>1 year, group II) and 20 healthy humans (group III) were determined with radioimmunoassay.


RESULTS
Compared with group III, the levels of plasma KP and ANP of the group I and group II were both higher (both P<0.01). Compared with group III, the level of KP/ANP of the group I was lower (P<0.01), while that of group II was no substantial change (P>0.05).


CONCLUSIONS
The change of levels in ANP, KP and ANP/KP may play important role in atrial fibrillation.
Ji
Da
D
Department of Emergency, General Hospital of People's Liberation Army, Beijing 100853, China.
Zeng
Qiang
Q
Shen
Hong
H
Fan
Ying-xian
YX
Chen
Wei
W
Song
Yang-li
YL
D001281:Atrial Fibrillation / Q000503:physiopathology*; D009320:Atrial Natriuretic Factor / Q000502:physiology*; D006801:Humans; D045265:Natriuretic Peptides / Q000378:metabolism; D011498:Protein Precursors / Q000502:physiology*
D045265:Natriuretic Peptides; D011498:Protein Precursors; C075322:atrial natriuretic factor precursor (79-98); D009320:Atrial Natriuretic Factor