Successful management of a P-incompatible pregnancy using double filtration plasmapheresis.
The presence of PP1Pk antibody is considered a main cause of repeated spontaneous abortions in early pregnancy. Because PP1Pk antibody generated in maternal blood may disturb the feto-maternal environment, plasmapheresis is supposed to be a beneficial method of lowering PP1Pk antibody levels in women with blood group-incompatible pregnancies. Double filtration plasmapheresis (DFPP) was used to treat feto-maternal P-incompatible pregnancy. The successful use of DFPP to treat a pregnant Japanese woman is presented. This method is a useful treatment for group P women who have not been able to deliver a live infant.
Taniguchi
Fuminori
F
Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan. tani4327@grape.med.tottori-u.ac.jp
Horie
Sayako
S
Tsukihara
Saroru
S
Nagata
Naoki
N
Nishikawa
Kenichi
K
Terakawa
Naoki
N
D000022:Abortion, Spontaneous / Q000276:immunology*; D000328:Adult; D001787:Blood Group Incompatibility / Q000628:therapy*; D002585:Cesarean Section; D005260:Female; D005865:Gestational Age; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000097:blood*; D010127:P Blood-Group System / Q000276:immunology*; D010956:Plasmapheresis / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome
D007126:Immunoglobulin Allotypes; D010127:P Blood-Group System