[Correction of hemodynamic disorders in phthisiologic surgical patients with chronic pulmonary heart disease in preoperative period].
The hypokinetic blood circulation was detected in 49% (from a total of 180) patients with different forms of pulmonary tuberculosis. Obvious initial signs of disorders in the function of the cardio-vascular system were diagnosed in one half of patients with the normal kinetic blood circulation. 48 patients underwent a preoperative treatment to correct the hemodynamic disorders. Isosorbide dinitrate (5 mg/day), verapamilhydrochlorid (240 mg/day), maleate enalapril (5 mg/day) and isosorbide dinirate (80 mg/day) were administered simultaneously. The preoperative preparation of patients lasted from 4 to 7 days. The cardiac beat, and the mechanical index of the functioning of the left ventricle essentially improved, while the total peripheral resistance significantly decreased due to all treatment schemes. Isosorbide dinitrate and verapamilhydrochlorid produced the most effect on the parameters of the central hemodynamics. The administration of all above preoperative preparation schemes in patients with pulmonary tuberculosis reduces the operation-anesthesiology risk.
Utkin
M M
MM
Kostoglotov
A V
AV
Sviridov
S V
SV
D004359:Drug Therapy, Combination; D004656:Enalapril / Q000627:therapeutic use; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D011300:Preoperative Care; D011660:Pulmonary Heart Disease / Q000209:etiology / Q000503:physiopathology*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000503:physiopathology*; D014665:Vasodilator Agents / Q000627:therapeutic use*; D014700:Verapamil / Q000627:therapeutic use
D014665:Vasodilator Agents; D004656:Enalapril; D014700:Verapamil; D007548:Isosorbide Dinitrate