Autologous allogeneic amniotic membrane grafting in Stevens-Johnson syndrome.
We describe the use of autologous allogeneic amniotic membrane in ocular surface reconstruction. A 28-year-old woman with cicatricial entropion from Stevens-Johnson syndrome had recurrent keratinization of the tarsal conjunctiva. Amniotic membrane from the patient's own conceptus was stored and successfully used in ocular surface reconstruction with improvement of ocular symptoms. Disease transmission is an important risk inherent in all human tissue transplantation. Use of carefully prepared autologous allogeneic amniotic membrane grafts should be considered in pregnant patients in need of ocular surface reconstruction.
Park
Eun-Ha
EH
Division of Ophthalmic Plastic and Reconstructive Surgery, UCSD Department of Ophthalmology, La Jolla, California 92093-0946, USA.
Korn
Tommy S
TS
Vasani
Sunil N
SN
Kikkawa
Don O
DO
D000650:Amnion / Q000637:transplantation*; D002921:Cicatrix / Q000209:etiology* / Q000601:surgery*; D004774:Entropion / Q000209:etiology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D049590:Postpartum Period; D011247:Pregnancy; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced / Q000150:complications*; D013457:Sulfur Compounds / Q000009:adverse effects; D014182:Transplantation, Autologous
D013457:Sulfur Compounds