AML1/ETO inhibits AML1/CCAAT-enhancer binding protein-alpha mediated activation of the CD11c promoter and represses CD11c expression in HL60 cells.
Drescher
Bettina
B
Nagel
Stefan
S
Krauter
Jürgen
J
Heidenreich
Olaf
O
Ganser
Arnold
A
Heil
Gerhard
G
D022763:CCAAT-Enhancer-Binding Protein-alpha / Q000037:antagonists & inhibitors*; D039521:CD11c Antigen / Q000235:genetics*; D050676:Core Binding Factor Alpha 2 Subunit; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors*; D018922:HL-60 Cells; D006801:Humans; D015514:Oncogene Proteins, Fusion / Q000037:antagonists & inhibitors / Q000502:physiology*; D011401:Promoter Regions, Genetic / Q000502:physiology*; D011518:Proto-Oncogene Proteins; D000075142:RUNX1 Translocation Partner 1 Protein; D014157:Transcription Factors / Q000037:antagonists & inhibitors* / Q000502:physiology*; D015533:Transcriptional Activation
C107844:AML1-ETO fusion protein, human; D022763:CCAAT-Enhancer-Binding Protein-alpha; D039521:CD11c Antigen; D050676:Core Binding Factor Alpha 2 Subunit; D004268:DNA-Binding Proteins; D015514:Oncogene Proteins, Fusion; D011518:Proto-Oncogene Proteins; D000075142:RUNX1 Translocation Partner 1 Protein; C493728:RUNX1 protein, human; D014157:Transcription Factors