title: Spiroheterocycles from reaction of nitrones with methylene-gamma-butyrolactones and some of their rearrangements.
abstract: Cycloaddition of nitrones 1 with methylene-gamma-butyrolactones 2, 3 and 4 afforded spiroadducts 5, 6 and 7 with high selectivity. Mixtures of diastereoisomers were usually obtained, whose structures were established by 1H and 13C NMR spectroscopies or X-ray crystallography. Treatment of spiroadducts in acidic and alkaline media led to different, unexpected and novel rearrangements.
authors.affiliation: Laboratoire de Chimie des Matériaux et Interfaces, UFR Sciences et Techniques, 16 Route de Gray, F-25030 Besancon, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Roussel
authors.forename: Rachid
authors.initials: R
authors.lastname: Fihi
authors.forename: Kabula
authors.initials: K
authors.lastname: Ciamala
authors.forename: Joël
authors.initials: J
authors.lastname: Vebrel
authors.forename: Touria
authors.initials: T
authors.lastname: Zair
authors.forename: Claude
authors.initials: C
authors.lastname: Riche