[Expression of chemokine-like factor 2 (CKLF2) mRNA in the rat myocardium after myocardial infarction].
OBJECTIVE
To investigate the expression of chemokine-like factor 2 (CKLF2) mRNA in the rat myocardium after myocardial infarction (MI).


METHODS
In a rat model of MI, the myocardium surrounding the infarcted area was used for RNA preparation at different time points. After RT, competitive polymerase chain reaction amplification was performed to assess the expression of rCKLF2 mRNA. SAS Kruskal-Wallis test was used for statistical comparisons.


RESULTS
The gene expression of rCKLF2 at mRNA level was significantly increased in the myocardium surrounding the infarcted area 3 days, 1 week, 2 weeks after infarction.


CONCLUSIONS
It is possible that CKLF2 contributes to the pathophysiological process and needs to be further investigated.
Gong
Yanjun
Y
Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
Hong
Tao
T
Jiang
Jie
J
Yu
Xue
X
Bu
Dingfang
D
Huo
Yong
Y
Gao
Wei
W
D000818:Animals; D018925:Chemokines / Q000378:metabolism*; D015870:Gene Expression; D009203:Myocardial Infarction / Q000378:metabolism*; D009206:Myocardium / Q000473:pathology*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger; D051381:Rats
C474963:CKLF2 protein, rat; D018925:Chemokines; D012333:RNA, Messenger