Calcium signalling: NAADP comes out of the shadows.
The molecular mechanisms through which extracellular stimuli mobilize intracellular Ca(2+) stores are still incompletely understood. Recent work suggests that nicotinic acid-adenine dinucleotide phosphate (NAADP) can finally join the ranks of genuine Ca(2+)-mobilizing second messengers.
Rutter
Guy A
GA
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, UK. g.a.rutter@bris.ac.uk
D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology; D020013:Calcium Signaling / Q000502:physiology*; D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology; D009249:NADP / Q000031:analogs & derivatives* / Q000502:physiology*; D015290:Second Messenger Systems / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology
D009249:NADP; C024376:NAADP