title: Direct lactonization of alkenols via osmium tetroxide-mediated oxidative cleavage.
abstract: [reaction: see text] A highly efficient, mild, and simple protocol is presented for the tandem OsO(4)-mediated oxidative cleavage/oxidative lactonization of alkenols to lactones. The protocol couples the OsO(4)-catalyzed oxidative cleavage of olefins with Oxone as the co-oxidant with the direct oxidation of aldehydes in alcoholic solvents to their corresponding esters.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Schomaker
authors.forename: Benjamin R
authors.initials: BR
authors.lastname: Travis
authors.forename: Babak
authors.initials: B
authors.lastname: Borhan