Cerebral toxoplasmosis after autologous peripheral blood stem cell transplantation.
Toxoplasmosis appears to be a rare opportunistic protozoal infection following haematopoietic stem cell transplantation (HSCT). Most cases have been reported in allogeneic HSCT recipients, with only anecdotal reports of infection occurring after autologous transplantation. Reported here is the case of a patient who developed cerebral toxoplasmosis following autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma.
López-Duarte
M
M
Department of Haematology, Hospital Universitario, Marqués de Valdecilla, Avenida de Valdecilla s/n, 39008 Santander (Cantabria), Spain. moini@navegalia.com
Insunza
A
A
Conde
E
E
Iriondo
A
A
Mazorra
F
F
Zubizarreta
A
A
D000935:Antifungal Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D004317:Doxorubicin / Q000009:adverse effects / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000276:immunology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D036102:Peripheral Blood Stem Cell Transplantation / Q000009:adverse effects*; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D016781:Toxoplasmosis, Cerebral / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014750:Vincristine / Q000009:adverse effects / Q000627:therapeutic use
D000935:Antifungal Agents; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone