title: Relation between recurrent vulvovaginal candidiasis, vaginal concentrations of mannose-binding lectin, and a mannose-binding lectin gene polymorphism in Latvian women.
abstract: Vaginal concentrations of mannose-binding lectin (MBL) and possession of a polymorphism in codon 54 of the MBL gene were determined in 42 women with recurrent vulvovaginal candidiasis (RVVC) and 43 control subjects. Reduced vaginal MBL levels and an increased occurrence of the polymorphism were present in women with RVVC.
authors.affiliation: Department of Obstetric and Gynecology, Weill Medical College of Cornell University, New York, NY 10021, USA.
authors.forename: Oksana
authors.initials: O
authors.lastname: Babula
authors.forename: Gunta
authors.initials: G
authors.lastname: Lazdane
authors.forename: Juta
authors.initials: J
authors.lastname: Kroica
authors.forename: William J
authors.initials: WJ
authors.lastname: Ledger
authors.forename: Steven S
authors.initials: SS
authors.lastname: Witkin
mesh_terms: D000293:Adolescent; D000328:Adult; D002176:Candida albicans / Q000187:drug effects / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism*; D003062:Codon / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007844:Latvia / Q000453:epidemiology; D037601:Mannose-Binding Lectin / Q000235:genetics* / Q000378:metabolism*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012008:Recurrence
chemical_list: D003062:Codon; D037601:Mannose-Binding Lectin