title: Electrocardiographic imaging of atrial and ventricular electrical activation.
abstract: Inverse electrocardiography has been developing for several years. By combining measurements obtained by electrocardiographic body surface mapping with three-dimensional anatomical data, one can non-invasively image the electrical activation sequence in the human heart. In this study, an imaging approach that uses a bidomain theory-based surface heart model was applied to single-beat data of atrial and ventricular activation. We found that for sinus and paced rhythms, the sites of early activation and the areas with late activation were estimated with sufficient accuracy. In particular, for focal arrhythmias, this model-based imaging approach might allow the guidance and evaluation of antiarrhythmic interventions, for instance, in case of catheter ablation or drug therapy.
authors.affiliation: University for Health Informatics and Technology Tyrol, Institute for Medical Signal Processing and Imaging, Innrain 98, Innsbruck 6020, Austria. bernhard.tilg@umit.at
authors.forename: Bernhard
authors.initials: B
authors.lastname: Tilg
authors.forename: Gerald
authors.initials: G
authors.lastname: Fischer
authors.forename: Robert
authors.initials: R
authors.lastname: Modre
authors.forename: Friedrich
authors.initials: F
authors.lastname: Hanser
authors.forename: Bernd
authors.initials: B
authors.lastname: Messnarz
authors.forename: Franz X
authors.initials: FX
authors.lastname: Roithinger
mesh_terms: D000328:Adult; D000368:Aged; D001282:Atrial Flutter / Q000175:diagnosis* / Q000503:physiopathology*; D018780:Body Surface Potential Mapping / Q000379:methods*; D006325:Heart Atria / Q000503:physiopathology*; D006329:Heart Conduction System / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014927:Wolff-Parkinson-White Syndrome / Q000175:diagnosis* / Q000503:physiopathology*