Study of the fragmentation mechanism of novel functionalized macrocycles by Fourier transform ion cyclotron resonance mass spectrometry.
Liquid secondary ion mass spectrometry (L-SIMS) of six new functionalized macrocycles was investigated. All six compounds yielded abundant fragment ions and protonation molecular ions [M + H](+) under L-SIMS conditions. The proposed fragmentation mechanisms were supported by high-resolution accurate mass data from Fourier transform ion cyclotron resonance mass spectrometric and MS(n) experiments on using sustained off-resonance irradiation collision-induced dissociation.
Chen
Hui
H
Department of Chemistry, Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Du
Da-Ming
DM
Hua
Wen-Ting
WT
He
Meiyu
M
Xin
Bin
B
D017357:Cyclotrons; D008401:Gas Chromatography-Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D006571:Heterocyclic Compounds / Q000032:analysis* / Q000737:chemistry; D015394:Molecular Structure; D017550:Spectroscopy, Fourier Transform Infrared / Q000295:instrumentation / Q000379:methods*
D006571:Heterocyclic Compounds