title: [Studies on correlation between protonation and tautomerism and luminescence characteristics of quinolone].
abstract: The fluorescence characteristics of 8 kinds of quinolone in different pH medium were studied. Rules of wavelength and intensity of the fluorescence in different pH medium were discovered. The correlation between the protonation, tautomerism and luminescence characteristics of quinolone are studied. It is found that in pH 6-8 or 2-4 there are two luminescence species. By this, the new view is represented that the change of luminescence characteristics is arised from the protonation and tautomerism of quinolones in different pH medium and the material point of luminescence developed in equilibrium system of tautomerism. Additionally, the correlation between the protonation, tautomerism and luminescence is further discussed.
authors.affiliation: Center of Analysis and Test, Shanxi Teacher's University, 041000 Linfen.
authors.forename: L
authors.initials: L
authors.lastname: Du
authors.forename: W
authors.initials: W
authors.lastname: Jin
authors.forename: C
authors.initials: C
authors.lastname: Dong
authors.forename: C
authors.initials: C
authors.lastname: Liu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002939:Ciprofloxacin / Q000737:chemistry*; D004735:Energy Transfer; D024841:Fluoroquinolones / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D049449:Luminescence; D015394:Molecular Structure; D009643:Norfloxacin / Q000737:chemistry*; D010879:Piperazines / Q000737:chemistry; D011522:Protons; D015363:Quinolones / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D010879:Piperazines; D011522:Protons; D015363:Quinolones; D002939:Ciprofloxacin; D009643:Norfloxacin