title: Ultrasound-guided percutaneous liver biopsy: indications, risks, and technique.
abstract: Percutaneous biopsy of the liver is the most specific test available currently to assess the nature and severity of liver diseases. Image-guidance either before or during the procedure has allowed this technique to be performed on a routine basis. The purpose of this article was to review the indications and contraindications for performing liver biopsy, and describe the spectrum of major and minor complications that can occur following biopsy. Equipment and biopsy needles available currently were compared, and the individual steps involved in ultrasound-guided biopsies described. Blinded versus ultrasound-guided biopsies were compared, and techniques used for selecting the most appropriate site for biopsy, reducing the passes through the liver, and reducing complications were discussed.
authors.affiliation: Section for Abdominal Imaging, Department of Radiology, Harvard Medical School Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
authors.forename: Laurian
authors.initials: L
authors.lastname: Copel
authors.forename: Jacob
authors.initials: J
authors.lastname: Sosna
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: Kruskal
authors.forename: Robert A
authors.initials: RA
authors.lastname: Kane
mesh_terms: D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods*; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional