title: [Treatment of congenital clinical anophthalmos with high hydrophilic hydrogel expanders].
abstract: BACKGROUND
  Children presenting with congenital anophthalmos usually develop a smaller bony orbit, a constricted mucosal socket, and a shortened eyelid fissure. This causes problems when fitting these patients with a prosthesis. Clinical evaluation of the Wiese self-inflating hydrogel expanders has demonstrated their ability to expand the socket and eyelid fissure for inserting a more realistic prosthesis in shorter periods of time.
  
  
  METHODS
  The study included 13 consecutive anophthalmic patients, eight unilateral and five bilateral. Each patient received a hemispherical osmotic tissue expander in the rudimentary mucosal socket and later a sphere implanted in the deeper soft orbital tissue.
  
  
  RESULTS
  The use of hydrogel expanders enlarged the lid and palpebral fissure in all children, with good cosmetic results. It allowed insertion of custom-made glass prostheses with good cosmetic appearance very early in life. Growth of the bony orbit may be stimulated successfully by these expanders in the soft orbital tissue.
  
  
  CONCLUSIONS
  The enlargement of constricted mucosal sockets and short palpebral fissures using self-inflating hydrogel expanders is a new and successful concept in treating congenital anophthalmos.
authors.affiliation: Universitätsaugenklinik Rostock. michael.schittkowski@med.uni-rostock.de
authors.forename: M P
authors.initials: MP
authors.lastname: Schittkowski
authors.forename: K K H
authors.initials: KK
authors.lastname: Gundlach
authors.forename: R F
authors.initials: RF
authors.lastname: Guthoff
mesh_terms: D000853:Anophthalmos / Q000534:rehabilitation*; D001672:Biocompatible Materials; D002648:Child; D002675:Child, Preschool; D005137:Eye, Artificial; D005500:Follow-Up Studies; D006801:Humans; D020100:Hydrogels; D007223:Infant; D008850:Microphthalmos / Q000534:rehabilitation*; D019919:Prosthesis Implantation; D015626:Tissue Expansion; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels