Mass transfer effects in preparative chromatography of eremomycin on polymeric sorbents.
This work is devoted to the study of the regularities of the sorption of the new antibacterial antibiotic eremomycin on carboxylic sorbents. The main sorption kinetic equilibrium and dynamic parameters for realization of one-act preparative chromatographic process were determined and the difference between gel-like and structurally segregated carboxylic cation exchangers was analyzed. The optimal conditions for sorption and complete desorption of eremomycin were found.
Polyakova
Irina V
IV
Department of Biopolymers, Institute of Molecular Compounds, Russian Academy of Sciences, Bolshoi Pr. 31, St. Petersburg, Russia.
Kolikov
Vsevolod M
VM
Pisarev
Oleg A
OA
D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D002411:Cation Exchange Resins; D002852:Chromatography, Ion Exchange / Q000379:methods*; D006020:Glycopeptides; D007700:Kinetics; D011108:Polymers / Q000737:chemistry*; D011199:Potentiometry
D000900:Anti-Bacterial Agents; D002411:Cation Exchange Resins; D006020:Glycopeptides; D011108:Polymers; C053759:eremomycin