title: Better success of retinal reattachment with long-standing gas tamponade in highly myopic eyes.
abstract: BACKGROUND
  To evaluate the efficacy of long-term gas tamponade after pars plana vitrectomy (PPV) for retinal detachment (RD) due to a macular hole (MH) in highly myopic eyes.
  
  
  METHODS
  A retrospective study was conducted at two institutions. The study included 25 highly myopic eyes with RD resulting from a MH. C3F8 gas tamponade was used in 13 eyes (C3F8 gas group), and SF6 gas tamponade was used in 12 eyes (SF6 gas group) following PPV. C3F8 gas has a longer half-life time in the vitreous cavity than SF6 gas. The main outcome measures were the anatomic reattachment rate and the visual acuity (VA). Follow-up periods were at least 24 months.
  
  
  RESULTS
  The anatomic reattachment rate and MH closure following the initial surgery were significantly higher in the C3F8 gas group (100%) than in the SF6 gas group (66.7%; P=0.039). The differences in the postoperative VAs were not significant both for all eyes and only for eyes with initial anatomic success. (P=0.42 and P=0.54, respectively). In addition, no significant difference was found in the improvement of VA both for all eyes and for the initial success eyes (P=0.66 and P=0.56, respectively).
  
  
  CONCLUSIONS
  We conclude that the longer duration of tamponade with C3F8 gas results in a higher rate of successful closure and that C3F8 gas tamponade is an effective treatment for MH with RD in highly myopic eyes.
authors.affiliation: Department of Ophthalmology, Toho University Sakura Hospital, 564-1 Shimoshizu, Sakura, 285-8741 Chiba, Japan. ruemoto@sakura.med.toho-u.ac.jp
authors.forename: Riyo
authors.initials: R
authors.lastname: Uemoto
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Saito
authors.forename: Shigeru
authors.initials: S
authors.lastname: Sato
authors.forename: Ayako
authors.initials: A
authors.lastname: Imaizumi
authors.forename: Masako
authors.initials: M
authors.lastname: Tanaka
authors.forename: Kazuto
authors.initials: K
authors.lastname: Nakae
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications*; D016684:Prone Position; D012163:Retinal Detachment / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012167:Retinal Perforations / Q000209:etiology; D012189:Retrospective Studies; D013459:Sulfur Hexafluoride / Q000008:administration & dosage*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*
chemical_list: D005466:Fluorocarbons; C042852:perflutren; D013459:Sulfur Hexafluoride