title: Successful management of a P-incompatible pregnancy using double filtration plasmapheresis.
abstract: The presence of PP1Pk antibody is considered a main cause of repeated spontaneous abortions in early pregnancy. Because PP1Pk antibody generated in maternal blood may disturb the feto-maternal environment, plasmapheresis is supposed to be a beneficial method of lowering PP1Pk antibody levels in women with blood group-incompatible pregnancies. Double filtration plasmapheresis (DFPP) was used to treat feto-maternal P-incompatible pregnancy. The successful use of DFPP to treat a pregnant Japanese woman is presented. This method is a useful treatment for group P women who have not been able to deliver a live infant.
authors.affiliation: Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan. tani4327@grape.med.tottori-u.ac.jp
authors.forename: Fuminori
authors.initials: F
authors.lastname: Taniguchi
authors.forename: Sayako
authors.initials: S
authors.lastname: Horie
authors.forename: Saroru
authors.initials: S
authors.lastname: Tsukihara
authors.forename: Naoki
authors.initials: N
authors.lastname: Nagata
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nishikawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Terakawa
mesh_terms: D000022:Abortion, Spontaneous / Q000276:immunology*; D000328:Adult; D001787:Blood Group Incompatibility / Q000628:therapy*; D002585:Cesarean Section; D005260:Female; D005865:Gestational Age; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000097:blood*; D010127:P Blood-Group System / Q000276:immunology*; D010956:Plasmapheresis / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: D007126:Immunoglobulin Allotypes; D010127:P Blood-Group System