title: Ludwig's angina: a clinical review.
abstract: Ludwig's angina is caused by a rapidly expanding cellulitis of the floor of the mouth and is characterized by a brawny induration of the floor and suprahyoid region (bilaterally), with an elevation of the tongue potentially obstructing the airway. In the pre-antibiotic era, Ludwig's angina was frequently fatal; however, antibiotics and aggressive surgical intervention have significantly reduced mortality. We reviewed nine patients with Ludwig's angina between July 1996 and June 2002, all of whom presented with fever, neck swelling, bilateral submandibular swelling and elevation of the tongue. In eight patients (89%) a dental infection appeared to be the underlying cause. High-dosage intravenous antibiotics directed towards the suspected causative microorganisms were given to all of the patients: two were treated successfully with conservative medical management, while seven underwent surgical drainage (a tracheotomy was necessary in one patient). Routine aerobic cultures were done on samples of drained material and the predominant microorganisms were Streptococcus species in two patients; there were none in the other five. Two patients had post-operative complications, but all recovered.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, 40002 Khon Kaen, Thailand. srirompotong@yahoo.com
authors.forename: Somchai
authors.initials: S
authors.lastname: Srirompotong
authors.forename: Thumnu
authors.initials: T
authors.lastname: Art-Smart
mesh_terms: D000046:Academic Medical Centers; D000293:Adolescent; D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000503:physiopathology*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002648:Child; D004322:Drainage / Q000379:methods; D005260:Female; D006760:Hospitalization; D006801:Humans; D008158:Ludwig's Angina / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009060:Mouth Floor / Q000382:microbiology / Q000473:pathology*; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications*; D013785:Thailand
chemical_list: D000900:Anti-Bacterial Agents