title: Antioxidant and antimicrobial activity of Cissus quadrangularis L.
abstract: Extracts of Cissus quadrangularis L. were tested for antioxidant activity by beta-carotene linoleic acid model and also by 1,1-diphenyl-2-picrylhydrazyl model. The ethyl acetate fraction of both fresh and dry stem extracts at a concentration of 100 ppm showed 64.8% antioxidant activity in the beta-carotene linoleic acid system and 61.6% in the 1,1-diphenyl-2-picrylhydrazyl system. This fraction showed the presence of sterols, vitamin C, and tannins as phytoconstituents. The antioxidant activity of methanol extract and aqueous extract were comparatively less significant than that of ethyl acetate extract, and n-hexane extract showed the least activity. The ethyl acetate extract and methanol extract of both fresh and dry stems further exhibited antimicrobial activity against Gram-positive bacteria, including Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Streptococcus species. The results of the study have implications in the use of C. quadrangularis as an antibacterial agent and more so as an antioxidant in several applications requiring these properties.
authors.affiliation: Cell Biotechnology Department, Central Food Technological Research Institute, Mysore 570 013, India.
authors.forename: K N
authors.initials: KN
authors.lastname: Chidambara Murthy
authors.forename: A
authors.initials: A
authors.lastname: Vanitha
authors.forename: M
authors.initials: M
authors.lastname: Mahadeva Swamy
authors.forename: G A
authors.initials: GA
authors.lastname: Ravishankar
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D001713:Biphenyl Compounds; D032422:Cissus / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D006834:Hydrazines; D010851:Picrates; D010936:Plant Extracts / Q000494:pharmacology*; D012997:Solvents
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D006834:Hydrazines; D010851:Picrates; D010936:Plant Extracts; D012997:Solvents; C004931:1,1-diphenyl-2-picrylhydrazyl