title: [Effect of different anesthesias on gastrointestinal motility after laparoscopic cholecystectomy].
abstract: OBJECTIVE
  To compare the effect of three different anesthesias on gastrointestinal motility after laparoscopic cholecystectomy (LC).
  
  
  METHODS
  Forty-two patients undergoing LC were randomly allocated to the combined epidural-general anesthesia group (Group A, n = 14), propofol-based total intravenous anesthesia group (Group B, n = 14) and isoflurane-based inhalational-intravenous general anesthesia group (Group G, n = 14). The concentration of plasma motilin was measured; the incidence of postoperative nausea and vomiting and the first flatus time were observed; and the in-hospital day was recorded.
  
  
  RESULTS
  1. The concentration of plasma motilin increased significantly during the first 1 h postoperatively (P < 0.05), but it had no significant difference in the 48 h after operation (P > 0.05) in comparison with the preoperative data in the three groups. The concentration of plasma motilin in Group C was much higher than that in the other two groups during the first 1 h postoperatively (P < 0.05). 2. The incidence of postoperative nausea and vomiting was much higher in Group C than that in the other two groups during the first 6 h postoperatively (P < 0.05), but there was no significant difference in the 6 h after operation in the three groups (P > 0.05). 3. The first flatus time and in-hospital day postoperatively had no statistical difference in the three groups (P > 0.05).
  
  
  CONCLUSIONS
  Different anesthesias do not influence the recovery of intestinal motion and in-hospital day postoperatively; the combined epidural-general anesthesia and propofol-based total intravenous anesthesia may be ideal anesthesias because of the lower incidence of postoperative nausea and vomiting.
authors.affiliation: Department of Anesthesiology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Liao
authors.forename: Ming-an
authors.initials: MA
authors.lastname: Wang
authors.forename: Wen
authors.initials: W
authors.lastname: Ouyang
mesh_terms: D000328:Adult; D000762:Anesthesia Recovery Period; D000767:Anesthesia, Epidural / Q000379:methods; D000768:Anesthesia, General / Q000379:methods; D000769:Anesthesia, Inhalation / Q000379:methods; D000771:Anesthesia, Intravenous; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D007530:Isoflurane; D008297:Male; D008875:Middle Aged; D020250:Postoperative Nausea and Vomiting / Q000209:etiology; D011184:Postoperative Period; D015742:Propofol
chemical_list: D007530:Isoflurane; D015742:Propofol