title: [Thermostability of granulated viral vaccines against avian Newcastle disease virus].
abstract: Stability infectivity of viral vaccines against Newcastle disease (ND) from strains La-Sota and Bor-74 VGNKI, prepared by using the method of granulation and spray-coating in fluidizated bed, was studied during the storage of vaccines at different temperatures. The infectious activity of the vaccines was found to remain stable for 6 months at 4 and 8 degrees C and for 2 weeks at (25 +/- 1) degree C. An analysis of the findings showed that an improved content of the preparation contributed to an essentially increased ND virus thermal stability in the granulated lactose-containing vaccine.
authors.forename: M G
authors.initials: MG
authors.lastname: Okroshidze
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000276:immunology / Q000517:prevention & control*; D006358:Hot Temperature; D009521:Newcastle Disease / Q000276:immunology / Q000517:prevention & control*; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D014765:Viral Vaccines