title: Flecainide induced ventricular tachycardia (torsades de pointes).
abstract: This case report describes a 68-year-old woman presenting with flecainide induced syncope due to torsades de pointes (TP) ventricular tachycardia. Before TP onset, the QTc interval reached 680 ms without changes in QRS duration. None of the usual triggers were found. Prolongation of QT under flecaïnide is exceptional and the occurrence of TP without concurrent triggers has not been reported in the literature.
authors.affiliation: Division of Cardiology, University Jean Monnet of Saint-Etienne, France.
authors.forename: Jerome
authors.initials: J
authors.lastname: Thevenin
authors.forename: Antoine
authors.initials: A
authors.lastname: Da Costa
authors.forename: Frederic
authors.initials: F
authors.lastname: Roche
authors.forename: Cecile
authors.initials: C
authors.lastname: Romeyer
authors.forename: Marc
authors.initials: M
authors.lastname: Messier
authors.forename: Karl
authors.initials: K
authors.lastname: Isaaz
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D005424:Flecainide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016171:Torsades de Pointes / Q000139:chemically induced*
chemical_list: D000889:Anti-Arrhythmia Agents; D005424:Flecainide