Bioactive glasses as accelerators of apatite bioactivity.
Synthetic carbonatehydroxyapatite is the ceramic closest to the mineral component of human bone and seems, therefore, the optimum material to use in osseous implants. However, in vitro assays performed to determine its bioactivity have shown no positive results after 2 months of assay. With the aim of improving this bioactivity, a new biphasic material was synthesized composed mainly of synthetic carbonatehydroxyapatite and only 5% of a sol-gel bioactive glass. In vitro assays were assessed to determine the bioactive behavior of this new material and revealed that the addition of a minimal amount of bioactive glass is enough to induce bioactivity on synthetic carbonatehydroxyapatites.
Vallet-Regí
M
M
Departamento de Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid. Pza. Ramón y Cajal s/n. 28040 Madrid, Spain. vallet@farm.ucm.es
Rámila
A
A
Padilla
S
S
Muñoz
B
B
D001031:Apatites; D001672:Biocompatible Materials; D005898:Glass; D008855:Microscopy, Electron, Scanning; D017550:Spectroscopy, Fourier Transform Infrared
D001031:Apatites; D001672:Biocompatible Materials