Are smoking and chlamydial infection risk factors for CIN? Different results after adjustment for HPV DNA and antibodies.
To identify the risk factors for cervical intraepithelial neoplasia (CIN), we reanalysed the data from our previous case-control study by adjusting for human papillomavirus (HPV) antibodies. Unlike our previous study based only on HPV DNA, smoking and Chlamydia trachomatis infection were revealed as significant risk factors for CIN after adjustment for HPV antibodies.
Matsumoto
K
K
Department of Obstetrics and Gynecology, University of Tokyo, Tokyo 113-8655, Japan. matsumok@mui.biglobe.ne.jp
Yasugi
T
T
Oki
A
A
Hoshiai
H
H
Taketani
Y
Y
Kawana
T
T
Yoshikawa
H
H
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D016022:Case-Control Studies; D002690:Chlamydia Infections / Q000150:complications*; D015986:Confounding Factors, Epidemiologic; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D016015:Logistic Models; D027383:Papillomaviridae / Q000235:genetics / Q000276:immunology; D030361:Papillomavirus Infections / Q000150:complications / Q000276:immunology; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D014412:Tumor Virus Infections / Q000150:complications / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000821:virology; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology* / Q000821:virology
D000914:Antibodies, Viral