[The relationship between clinical changes in schizophrenia, acoustic evoked potentials, and background electroencephalogram].
The study was made of relationship between the dynamics of neurophysiological parameters and the changes of clinical state assessed by the PANSS and the CGI in 17 male patients with schizophrenia. Significant correlations between the reduction of psychopathological symptoms by PANSS and an increase of P300 amplitude and spectral density of background EEG in delta-, theta-, alpha 1- and alpha 3-ranges and the reduction of psychotic symptoms by CGI and an increase density in delta-, theta-, alpha 1-diapasons were found. The findings are considered as the evidence of correlations between an improvement of clinical state and "normalization" of different processes of attention, thinking and memory reflected changes of the tested EEG parameters.
Lebedeva
I S
IS
Kaleda
V G
VG
Tsutsul'kovskaia
M Ia
MIa
D000328:Adult; D001288:Attention / Q000502:physiology; D004569:Electroencephalography; D018913:Event-Related Potentials, P300; D005072:Evoked Potentials, Auditory; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology; D012559:Schizophrenia / Q000503:physiopathology*; D013850:Thinking / Q000502:physiology