title: Infrequent early recanalization of greater saphenous vein after endovenous laser treatment.
abstract: OBJECTIVE
  The frequency of recanalization of the greater saphenous vein (GSV) after endovenous laser treatment (ELT) is unclear. This study was undertaken to establish the incidence of early recanalization after ELT and to study the histopathologic features of reperfused and excised GSV.
  
  
  METHODS
  One hundred nine GSV in 85 consecutive patients with clinical stage C(2-6) E(P,S) A(S,P,D) P(R) disease were treated with ELT. Twelve months of follow-up with duplex scanning at regular intervals was possible in 104 treated veins (95.4%) in 82 patients (96.5%). Recanalized vessels were removed surgically and examined at histopathology.
  
  
  RESULTS
  ELT-induced occlusion proved permanent at duplex scanning over 12 months of follow-up in 94 of 104 GSV (90.4%) in 73 patients. In 4 patients, 5 GSV (4.8%) were recanalized completely after 1 week, after 3 months (n = 3), or after 12 months. Another 5 GSV (4.8%) in 5 patients exhibited incomplete proximal recanalization over the 12 months of follow-up. Finally, 9 recanalized vessels (8.6%) required further treatment with high ligation and stripping. Histopathologic analysis of recanalized GSV revealed a multiluminal pattern, as commonly noted in reperfusion after spontaneous thromboplebotic occlusion of the GSV. During follow-up, secondary incompetency of untreated lateral accessory saphenous veins was observed in two legs (1.9%).
  
  
  CONCLUSIONS
  Early recanalization requiring retreatment is observed in less than 10% of GSV after ELT. The histopathologic pattern mimics recanalization after thrombophlebotic occlusion.
authors.affiliation: Department of Dermatology, University of Mainz, Mainz, Germany. Thomas.Proebstle@web.de
authors.forename: T M
authors.initials: TM
authors.lastname: Proebstle
authors.forename: D
authors.initials: D
authors.lastname: Gül
authors.forename: H A
authors.initials: HA
authors.lastname: Lehr
authors.forename: A
authors.initials: A
authors.lastname: Kargl
authors.forename: J
authors.initials: J
authors.lastname: Knop
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012086:Reoperation; D018570:Risk Assessment; D012501:Saphenous Vein; D012720:Severity of Illness Index; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014654:Vascular Patency / Q000502:physiology; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*