title: Cytosine analogues from substituted acetonitriles via Thorpe condensation.
abstract: [reaction: see text] A Thorpe condensation is the key bond construction in a rapid and efficient synthesis of substituted cytosine derivatives from readily available starting materials.
authors.affiliation: Department of Chemistry, Brown University, Providence, Rhode Island 02912, USA.
authors.forename: Julia L
authors.initials: JL
authors.lastname: Barkin
authors.forename: Marcus D
authors.initials: MD
authors.lastname: Faust
authors.forename: William C
authors.initials: WC
authors.lastname: Trenkle
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D000215:Acylation; D003500:Cyclization; D003596:Cytosine / Q000031:analogs & derivatives*; D004987:Ethers / Q000737:chemistry; D017953:Isocyanates / Q000737:chemistry; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry
chemical_list: D000097:Acetonitriles; D004987:Ethers; D017953:Isocyanates; D011743:Pyrimidines; D003596:Cytosine