A novel and direct synthesis of alkylated 2,2'-bithiophene derivatives using a combination of hypervalent iodine(III) reagent and BF3.Et2O.
A novel nonmetallic oxidative coupling of alkylthiophene derivatives leading to the corresponding 2,2'-bithiophene derivatives using a combination of a hypervalent iodine(III) reagent, phenyliodine bis(trifluoroacetate) (PIFA), and BF3.Et2O was developed.
Tohma
Hirofumi
H
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Iwata
Minako
M
Maegawa
Tomohiro
T
Kiyono
Yorito
Y
Maruyama
Akinobu
A
Kita
Yasuyuki
Y