Localized aggressive periodontitis in primary dentition: a case report.
BACKGROUND
A 5-year-old Japanese boy presented with persistent gingival inflammation and severe mobility of the right lower primary incisors. Due to severe alveolar bone loss and a deep periodontal pocket (5 mm), the incisors were extracted at the second visit.


METHODS
Clinical, radiographic, histological, and microbiological examinations were carried out. Then, the polymerase chain reaction (PCR) technique was employed to detect specific periodontal pathogens. The chemotactic activity of polymorphonuclear neutrophils was also measured.


RESULTS
Tannerella, Capnocytophaga, Fusobacterium, and Eikenella sp. were recovered from the subgingival microflora around the right lower incisors, while A. actinomycetemcomitans, Tannerella forsythensis (formerly Bacteroides forsythus), Prevotella nigrescens, Campylobacter rectus, and Capnocytophaga gingivalis were detected using the PCR method. Further chemotaxis assay revealed that neutrophil function was depressed compared with that of healthy controls.


CONCLUSIONS
Although inflammation remained around the right primary second molars, the bone loss was controlled by periodic professional mechanical teeth cleaning (PMTC), subgingival irrigation, and local antibiotic application. The probing depths of all teeth, including permanent incisors and molars, were within 2.5 mm.
Suzuki
Junji
J
Department of Pediatric Dentistry, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. Junji-hma@umin.ac.jp
Okada
Mitsugi
M
Wang
Yurong
Y
Nii
Noriko
N
Miura
Kazuo
K
Kozai
Katsuyuki
K
D016301:Alveolar Bone Loss / Q000175:diagnosis / Q000382:microbiology; D002634:Chemotaxis, Leukocyte / Q000502:physiology; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000502:physiology; D010518:Periodontitis / Q000175:diagnosis* / Q000382:microbiology; D014094:Tooth, Deciduous / Q000473:pathology*