title: SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism.
abstract: In this study no one of our 85 patients of Serbian origin with young-onset (</= 45 years) dopa-responsive parkinsonism (YOP), previously proved negative for PARK1 and PARK2 mutations, had either spinocerebellar ataxia type 2 (SCA2) or SCA3 mutation. These data do not prove the significance of these two mutations in either sporadic or familial YOP suggestive of Parkinson's disease.
authors.affiliation: Institute of Neurology CCS, School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: M
authors.initials: M
authors.lastname: Svetel
authors.forename: A
authors.initials: A
authors.lastname: Djarmati
authors.forename: N
authors.initials: N
authors.lastname: Dragasević
authors.forename: D
authors.initials: D
authors.lastname: Savić
authors.forename: B
authors.initials: B
authors.lastname: Culjković
authors.forename: S
authors.initials: S
authors.lastname: Romac
authors.forename: V S
authors.initials: VS
authors.lastname: Kostić
mesh_terms: D000328:Adult; D017668:Age of Onset; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D017827:Machado-Joseph Disease / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D020734:Parkinsonian Disorders / Q000188:drug therapy / Q000235:genetics* / Q000503:physiopathology; D020754:Spinocerebellar Ataxias / Q000235:genetics*; D015022:Yugoslavia
chemical_list: D007980:Levodopa