R3Al-R'3SiOTf: novel and powerful reagent system for stereospecific alkylation-silylation reactions of epoxides.
[reaction: see text] A novel and powerful reagent system R(3)Al-R'(3)SiOTf for the one-pot alkylation-silylation reaction of epoxides was discovered, and the reactions of various epoxides with the new reagent system have been demonstrated to occur stereospecifically giving rise to the corresponding alkylation-silylation products in excellent yields.
Shanmugam
Ponnusamy
P
Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.
Miyashita
Masaaki
M