[Detection of anti-HCV in blood recipients with hematonosis].
OBJECTIVE
To observe hepatitis C virus (HCV) infection in blood recipients with hematonosis, and to investigate the significance of anti-HCV detection in the patients.


METHODS
Anti-HCV was detected by enzyme-linked immunosorbent assay (ELISA) in 176 hematonosis patients before blood transfusion, the result of anti-HCV was compared with control (417 cases), and 95 blood recipients were followed up for 6-12 months after the transfusion.


RESULTS
The positive rate of anti-HCV was 5.68% (10/176) in hematonosis patients before transfusion, higher than both in the control [0.72% (3/417), P < 0.01] and in the patients with general surgery [2.23% (21/942), P < 0.05], and no new infection case was found after the transfusion.


CONCLUSIONS
HCV infectionin in blood recipients with hematonosis should be paid attention to, and the detection of anti-HCV is necessary for patients before blood transfusion.
Liu
Jing
J
Department of Hematology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Jiang
Tie-bin
TB
Wen
Feng
F
D000741:Anemia, Aplastic / Q000628:therapy; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000276:immunology / Q000302:isolation & purification*; D006526:Hepatitis C / Q000635:transmission / Q000821:virology; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D008297:Male; D065227:Transfusion Reaction
D018937:Hepatitis C Antibodies