title: [Topical methylprednisolone vs lidocaïne for the prevention of postoperative sore throat].
abstract: OBJECTIVE
  We assessed the efficacy of topical methylprednisolone or lidocaine for prevention of postoperative sore throat.
  
  
  METHODS
  Randomised, prospective in single blind study.
  
  
  METHODS
  Sixty patients ASA 1 or 2 undergoing tracheal intubation for dental surgery received before intubation either topical lidocaine 5% (15 puffs) or aerosolized methylprednisolone (80 mg). Postoperative pain was assessed by the patients using a VAS and a specific scoring system for sore throat, cough and hoarseness. Evaluations were performed immediately after emergence from anaesthesia, 1 h later, at time of the first postoperative drink, at time of the first postoperative meal and 24 h after surgery.
  
  
  RESULTS
  Patients receiving methylprednisolone showed slightly better scores for sore throat and cough 1 h after surgery.
  
  
  CONCLUSIONS
  Topical methylprednisolone may therefore be a useful adjuvant in the prevention of sore throat after intubation.
authors.affiliation: Département d'anesthésie-réanimation, CHU La Timone, 264, rue Saint-Pierre, 13005 Marseille, France. barbaralevy@doctor.com
authors.forename: B
authors.initials: B
authors.lastname: Lévy
authors.forename: F
authors.initials: F
authors.lastname: Mouillac
authors.forename: D
authors.initials: D
authors.lastname: Quilichini
authors.forename: J
authors.initials: J
authors.lastname: Schmitz
authors.forename: J
authors.initials: J
authors.lastname: Gaudart
authors.forename: F
authors.initials: F
authors.lastname: Gouin
mesh_terms: D000328:Adult; D000336:Aerosols; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000627:therapeutic use*; D003371:Cough / Q000453:epidemiology / Q000517:prevention & control; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000627:therapeutic use*; D006685:Hoarseness / Q000517:prevention & control; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D008012:Lidocaine / Q000008:administration & dosage* / Q000627:therapeutic use*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use*; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010612:Pharyngitis / Q000209:etiology / Q000517:prevention & control*; D016037:Single-Blind Method
chemical_list: D000336:Aerosols; D000779:Anesthetics, Local; D005938:Glucocorticoids; D008012:Lidocaine; D008775:Methylprednisolone