title: Chronic myelomonocytic leukemia with abnormal bone marrow eosinophils.
abstract: Chronic myelomonocytic leukemia with eosinophilia is a recently defined rare entity frequently associated with t(5;12)(q33;p13) translocation. It usually shows a peripheral eosinophil count greater than 1500/microL. However, the literature contains a small subset of cases in which the major manifestation is bone marrow eosinophilia. We report a case similar to that subset and discuss our finding that the immature eosinophils are identical to those seen in acute myelomonocytic leukemia with abnormal bone marrow eosinophils.
authors.affiliation: Department of Pathology, University of Colorado Health Science Center, Denver, CO 80262, USA. jason.hyde@uchsc.edu
authors.forename: Jason
authors.initials: J
authors.lastname: Hyde
authors.forename: Tsieh
authors.initials: T
authors.lastname: Sun
mesh_terms: D001853:Bone Marrow / Q000473:pathology*; D004802:Eosinophilia / Q000097:blood / Q000150:complications; D004804:Eosinophils / Q000473:pathology*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D015477:Leukemia, Myelomonocytic, Chronic / Q000150:complications / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged