title: [Immaturity or hypotrophy? The cord blood leptin levels in preterm and small-for-gestational age neonates].
abstract: OBJECTIVE
  To assess cord blood leptin levels in preterm and small-for-gestational age neonates and determine whether fetal leptin levels correlate with selected clinical parameters associated with prematurity and undernutrition at birth.
  
  
  METHODS
  Study of preterm newborns (p-AGA; n = 31) and small-for-gestational age (t-SGA; n = 23) cases in a population of neonates born in Szczecin between September 2001 and June 2002.
  
  
  METHODS
  Fetal cord blood was sampled after delivery. Leptin levels were measured by RIA. Anthropometric data (birth weight, birth length, head and chest circumferences, body mass index, Ponderal index) were also recorded.
  
  
  RESULTS
  Cord blood leptin levels did not differ significantly between p-AGA and t-SGA neonates with similar birthweight. Among the two groups of newborns the correlations between fetal leptin and anthropometric data were only observed in p-AGAs, but not in t-SGA group.
  
  
  CONCLUSIONS
  We suggest that cord blood leptin level depends on body mass rather than maturity of newborn. It is also hypothesized that leptin level in SGA neonates is determined by other than anthropometric parameters used in this study.
authors.affiliation: Samodzielnej Pracownii Propedeutyki Chorób Dzieci Katedry Chorób Dzieci PAM, Szczecinie.
authors.forename: Barbara
authors.initials: B
authors.lastname: Garanty-Bogacka
authors.forename: Maria Beata
authors.initials: MB
authors.lastname: Czeszyńska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Syrenicz
authors.forename: Aneta
authors.initials: A
authors.lastname: Gebala
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kordek
authors.forename: Dorota
authors.initials: D
authors.lastname: Janus
authors.forename: Mieczysław
authors.initials: M
authors.lastname: Walczak
authors.forename: Beata
authors.initials: B
authors.lastname: Krupa
authors.forename: Paula
authors.initials: P
authors.lastname: Szołomicka-Kurzawa
authors.forename: Ryszard
authors.initials: R
authors.lastname: Czajka
mesh_terms: D001724:Birth Weight; D015992:Body Mass Index; D005314:Embryonic and Fetal Development; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007234:Infant, Premature / Q000097:blood*; D007236:Infant, Small for Gestational Age / Q000097:blood*; D020738:Leptin / Q000097:blood*; D008297:Male; D015999:Multivariate Analysis; D011247:Pregnancy
chemical_list: D020738:Leptin