Observation of high enantioselectivity for the gas phase hydrogenation of methyl pyruvate using supported Pt catalysts pre-modified with cinchonidine.
Pt supported on alpha-Al2O3, gamma-Al2O3 and SiO2 pre-modified with cinchonidine gives over 50% ee in the hydrogenation of methyl pyruvate to methyl lactate using gas phase reactants at 40 degrees C giving the first clear observation of high enantioselection at the gas/solid interface.
von Arx
Matthias
M
Department of Chemistry, Cardiff University, PO Box 912, Cardiff, UK CF10 3TB.
Dummer
Nicholas
N
Willock
David J
DJ
Taylor
Stuart H
SH
Wells
Richard P K
RP
Wells
Peter B
PB
Hutchings
Graham J
GJ