Synthesis of highly substituted 1,3-dienes and 1,3,5-trienes by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes.
[reaction: see text] Highly substituted 1,3-dienes and trienes have been prepared in good to excellent yields by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes.
Zhang
Xiaoxia
X
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Larock
Richard C
RC