Better biosynthesis of ergot alkaloids.
Different culture media containing different effectors for production of ergot-alkaloids were prepared. The culture media were inoculated with equal mycelia of Claviceps purpurea and some were incubated for 22 days and some incubated for 45 days. The medium that contained a mixture of glucose, glycine and tryptophan showed highest yield of the alkaloids and reached the maximum period for production of agroclavine faster.
Okide
G B
GB
Department of Pharmaceutical Chemistry, University of Nigeria, Nsukka-Nigeria.
Ajali
U
U
D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000302:isolation & purification; D002967:Claviceps / Q000378:metabolism*; D003470:Culture Media; D004873:Ergolines / Q000302:isolation & purification; D004876:Ergot Alkaloids / Q000096:biosynthesis*
D000903:Antibiotics, Antineoplastic; D003470:Culture Media; D004873:Ergolines; D004876:Ergot Alkaloids; C004465:agroclavine