Synthesis and cytotoxic evaluation of novel thiazolocarbazoles. Part III.
Novel thiazolocarbazole derivatives have been synthesized via the corresponding imino-1,2,3-dithiazoles. In vitro antitumor activity of these polyheterocyclic compounds was studied.
Chabane
Hadjila
H
Laboratoire de Génie Protéique et Cellulaire, EA3169, Groupe de Chimie Organique, UFR Sciences Fondamentales et Sciences pour l'Ingénieur, Bâtiment Marie Curie, Université, de la Rochelle, F-17042 La Rochelle cedex 1, France.
Lamazzi
Christelle
C
Thiery
Valerie
V
Pierre
Alain
A
Leonce
Stephane
S
Pfeiffer
Bruno
B
Renard
Pierre
P
Guillaumet
Gérald
G
Besson
Thierry
T
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002227:Carbazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D020128:Inhibitory Concentration 50; D007939:Leukemia L1210 / Q000473:pathology; D051379:Mice; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000970:Antineoplastic Agents; D002227:Carbazoles; D013844:Thiazoles