title: Postoperative complications among octogenarians after cardiovascular surgery.
abstract: BACKGROUND
  The octogenarian patient is often perceived as too fragile to undergo cardiothoracic surgery. Our study aimed to compare postoperative complications in patients aged less than 80 versus elderly patients (80 years or more) after surgical cardiac intervention (coronary artery bypass or valve replacement).
  
  
  METHODS
  Subjects were all patients (n = 8,361) who had an open-heart procedure, either coronary artery bypass or valve implantation or replacement, at two medical centers located in northern Virginia using the same surgical group. A computerized medical record database was reviewed to determine preoperative risk factors and postoperative outcomes. Predictors of complications were identified by univariate and multivariate logistic regression.
  
  
  RESULTS
  A total of 3,214 complications were recorded. The most prevalent complications were prolonged ventilation time in the intensive care unit, reoperation for bleeding, and pneumonia. The overall mortality rate was 2.4% (204 of 8,361). Persons aged over 80 years had nearly double the mortality rate compared with younger patients (4.1% [18 of 444] to 2.3% [186 of 7,917]). Age greater than 80 years (odds ratio = 2.65, 95% confidence interval = 2.18 to 3.22) and male gender (odds ratio = 0.62, 95% confidence interval = 0.56 to 0.69) were the best univariate predictors of a single postoperative complication.
  
  
  CONCLUSIONS
  Octogenarian patients manifested twice the risk of death from a cardiac intervention with an average 2-day longer hospital stay compared with their younger counterparts. Furthermore, octogenarians were at markedly higher risk of nonfatal postoperative complications.
authors.affiliation: Inova Heart Institute at Inova Fairfax Hospital, Falls Church, Virginia 22042, USA. scott.barnett@inova.com
authors.forename: Scott D
authors.initials: SD
authors.lastname: Barnett
authors.forename: Linda S
authors.initials: LS
authors.lastname: Halpin
authors.forename: Alan M
authors.initials: AM
authors.lastname: Speir
authors.forename: Robert A
authors.initials: RA
authors.lastname: Albus
authors.forename: Bechara F
authors.initials: BF
authors.lastname: Akl
authors.forename: Paul S
authors.initials: PS
authors.lastname: Massimiano
authors.forename: Nelson A
authors.initials: NA
authors.lastname: Burton
authors.forename: Lucas R
authors.initials: LR
authors.lastname: Collazo
authors.forename: Edward A
authors.initials: EA
authors.lastname: Lefrak
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D013504:Cardiovascular Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies