Synthesis of 1-triazolyl-4-trimethylsilyl-2-butanol and 1-triazolyl-5-trimethylsilyl-2-pentanol derivatives and an investigation of their fungicidal activities.
A new series of azole derivatives of 1-triazolyl-4-trimethylsilyl-2-butanol and 1-triazolyl-5-trimethylsilyl-2-pentanol were synthesized and evaluated for fungicidal activities against rice blast, sheath blight, and powdery mildew on barley. The derivatives of 2,4-difluorobenzene exhibited high antifungal activities when applied by spray, but exhibited no fungicidal activity by submerged application.
Itoh
Hiroyuki
H
Agroscience Research Laboratories, Sankyo Co., Ltd., Shiga, Japan. hiroit@yasu.sankyo.co.jp
Yoneda
Rieko
R
Tobitsuka
Junzo
J
Ohta
Hiroshi
H
Takahi
Yukiyoshi
Y
Tsuda
Mikio
M
Takeshiba
Hideo
H
D001203:Ascomycota / Q000187:drug effects; D005659:Fungicides, Industrial / Q000138:chemical synthesis* / Q000494:pharmacology*; D001467:Hordeum; D009682:Magnetic Resonance Spectroscopy; D012275:Oryza / Q000382:microbiology; D010935:Plant Diseases / Q000382:microbiology; D012232:Rhizoctonia / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D014297:Trimethylsilyl Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*
C483341:1-triazolyl-4-trimethylsilyl-2-butanol; C483342:1-triazolyl-5-trimethylsilyl-2-pentanol; D005659:Fungicides, Industrial; D014230:Triazoles; D014297:Trimethylsilyl Compounds