Pathologic study of acute toxoplasmosis in experimental animals.
We studied the pathology of acute toxoplasmosis in experimental mice inoculated with RH strain tachyzoites of Toxoplasma gondii. All died from severe disseminated toxoplasmosis involving the liver, spleen and pancreas. Pathological features of acute toxoplasmosis in susceptible mice could be regarded as an excellent model for acute reactivation of Toxoplasma in the immunosuppressed host.
Sukthana
Yaowalark
Y
Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. tmymv@mahidol.ac.th
Waree
Phuangphet
P
Pongponratn
Emsri
E
Chaisri
Urai
U
Riganti
Mario
M
D000208:Acute Disease; D000818:Animals; D051379:Mice; D008854:Microscopy, Electron; D014122:Toxoplasma / Q000472:pathogenicity*; D014124:Toxoplasmosis, Animal / Q000473:pathology*