Acquired reactive perforating collagenosis in a nondiabetic hemodialysis patient: successful treatment with allopurinol.
The authors present a case of acquired reactive perforating collagenosis developed in a nondiabetic hemodialysis patient, who was treated successfully with allopurinol. Treatment of acquired reactive perforating collagenosis is difficult and often ineffective. The patient had been unresponsive to conventional treatments, but the pruritus was controlled, and skin lesions subsequently resolved after the treatment with allopurinol. Possible mechanisms of allopurinol treatment for acquired reactive perforating collagenosis are discussed.
Iyoda
Masayuki
M
Department of Internal Medicine, Tokyu Hospital, Tokyo, Japan. iyoda@med.showa-u.ac.jp
Hayashi
Fumihiro
F
Kuroki
Aki
A
Shibata
Takanori
T
Kitazawa
Kozo
K
Sugisaki
Tetsuzo
T
Sakai
Osamu
O
D000493:Allopurinol / Q000627:therapeutic use*; D003095:Collagen Diseases / Q000188:drug therapy / Q000209:etiology*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology; D006435:Renal Dialysis; D012875:Skin Diseases, Metabolic / Q000188:drug therapy / Q000209:etiology*
D004791:Enzyme Inhibitors; D000493:Allopurinol