title: [Identification of four new ceramides from Anthopleura pacifica].
abstract: OBJECTIVE
  To study the bioactive constituents from Anthopleura pacifica.
  
  
  METHODS
  Compounds were separated by Pyricularia oryzae bioassay-guided fractionation method with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence.
  
  
  RESULTS
  A portion showing activity against P. oryzae was obtained and from the portion four compounds were identified as N-hydroxyethyl-N-tetradecanoyl-(2S,3R)-octadecasphinga-4(E), 8(E)-dienine (a), N-hydroxyethyl-N-(9Z-hexadecenoyl)-(2S,3R)-octadecasphinga-4 (E), 8 (E)-dienine (b), N-hydroxyethyl-N-hexadecanoyl-(2S,3R)-octadecasphinga-4(E), 8 (E)-dienine (c) and N-hydroxyethyl-N-(13Z-docosenoyl-(2S,3R)-octadecasphinga-4(E), 8(E)-dienine(d).
  
  
  CONCLUSIONS
  All the four compounds are new ceramides.
authors.affiliation: Resarch Center for Marine Drugs, College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
authors.forename: Shu-yu
authors.initials: SY
authors.lastname: Zhang
authors.forename: Hai-feng
authors.initials: HF
authors.lastname: Tang
authors.forename: Yang-hua
authors.initials: YH
authors.lastname: Yi
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.forename: Da-zheng
authors.initials: DZ
authors.lastname: Zhou
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Zou
mesh_terms: D000818:Animals; D001681:Biological Assay; D002518:Ceramides / Q000737:chemistry / Q000302:isolation & purification*; D003064:Cnidarian Venoms / Q000737:chemistry*; D003904:Mitosporic Fungi / Q000187:drug effects*; D008968:Molecular Conformation; D015394:Molecular Structure; D012615:Sea Anemones / Q000737:chemistry*
chemical_list: D002518:Ceramides; D003064:Cnidarian Venoms