title: Acquired reactive perforating collagenosis in a nondiabetic hemodialysis patient: successful treatment with allopurinol.
abstract: The authors present a case of acquired reactive perforating collagenosis developed in a nondiabetic hemodialysis patient, who was treated successfully with allopurinol. Treatment of acquired reactive perforating collagenosis is difficult and often ineffective. The patient had been unresponsive to conventional treatments, but the pruritus was controlled, and skin lesions subsequently resolved after the treatment with allopurinol. Possible mechanisms of allopurinol treatment for acquired reactive perforating collagenosis are discussed.
authors.affiliation: Department of Internal Medicine, Tokyu Hospital, Tokyo, Japan. iyoda@med.showa-u.ac.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iyoda
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Hayashi
authors.forename: Aki
authors.initials: A
authors.lastname: Kuroki
authors.forename: Takanori
authors.initials: T
authors.lastname: Shibata
authors.forename: Kozo
authors.initials: K
authors.lastname: Kitazawa
authors.forename: Tetsuzo
authors.initials: T
authors.lastname: Sugisaki
authors.forename: Osamu
authors.initials: O
authors.lastname: Sakai
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use*; D003095:Collagen Diseases / Q000188:drug therapy / Q000209:etiology*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology; D006435:Renal Dialysis; D012875:Skin Diseases, Metabolic / Q000188:drug therapy / Q000209:etiology*
chemical_list: D004791:Enzyme Inhibitors; D000493:Allopurinol