title: Diffusion-weighted MR imaging in intracranial infections.
abstract: BACKGROUND
  Diffusion-weighted magnetic resonance (MR) imaging (DWMRI) is valuable in the assessment of acute cerebral infarction and may be useful for other diseases of the central nervous system (CNS). In this study, we present the DWMRI appearance of intracranial infection.
  
  
  METHODS
  Thirty patients with clinical diagnosis of CNS infection were reviewed. All patients underwent conventional contrast-enhanced MR examination and DWMRI using single-shot echo-planar imaging at b = 1000 s/mm2.
  
  
  RESULTS
  Cerebral abscess, tuberculoma, subdural empyema and epidural abscess were hyperintense on DWMRI. Neurocysticercosis showed hypointense lesions on DWMRI. Four of 5 patients with encephalitis showed DWMRI hyperintensity; the appearance of toxoplasmosis lesions was variable. Patients suffering from meningitis without parenchymal involvement did not exhibit any abnormality of diffusion. One patient with tuberculous meningitis developed abnormality on DWMRI from acute cerebral infarction.
  
  
  CONCLUSIONS
  DWMRI increased lesion conspicuity and may be useful in assessment of cerebral infection. There were striking differences in the DWMRI appearances caused by different organisms and diseases.
authors.affiliation: Department of Neuroradiology, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433. tchoyoson_lim@notes.ttsh.gov.sg
authors.forename: C C
authors.initials: CC
authors.lastname: Lim
authors.forename: W
authors.initials: W
authors.lastname: Lee
authors.forename: S M
authors.initials: SM
authors.lastname: Chng
authors.forename: Y Y
authors.initials: YY
authors.lastname: Sitoh
authors.forename: F
authors.initials: F
authors.lastname: Hui
mesh_terms: D001922:Brain Abscess / Q000175:diagnosis*; D015331:Cohort Studies; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D004660:Encephalitis / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D012846:Singapore