title: FT-IR spectroscopic analysis of normal and cancerous tissues of esophagus.
abstract: OBJECTIVE
  To investigate the special Fourier transform infrared spectroscopy (FT-IR) spectra in normal and cancerous tissues of esophagus.
  
  
  METHODS
  Twenty-seven pairs of normal and cancerous tissues of esophagus were studied by using FT-IR and the special spectra characteristics were analyzed in different tissues.
  
  
  RESULTS
  Different spectra were found in normal and cancerous tissues. The peak at 1 550/cm was weak and wide in cancerous tissues but strong and high in normal tissues. The ratio of I 1 647/I 1 550 was 2.0 in normal tissues and 2.36 in cancerous tissues (P<0.05). The ratio of I 1 550/I 1 080 was 4.5 in normal tissues and 3.4 in cancerous tissues (P<0.01). The peak at 1453 /cm was higher than at 1 402/cm in normal tissue and lower than at 1 402/cm in cancerous tissues.
  
  
  CONCLUSIONS
  The results indicate that FTIR may be used in clinical diagnosis.
authors.affiliation: Department of Oncological Surgery, First Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
authors.forename: Jian-Sheng
authors.initials: JS
authors.lastname: Wang
authors.forename: Jing-Sen
authors.initials: JS
authors.lastname: Shi
authors.forename: Yi-Zhuang
authors.initials: YZ
authors.lastname: Xu
authors.forename: Xiao-Yi
authors.initials: XY
authors.lastname: Duan
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Yang
authors.forename: Shi-Fu
authors.initials: SF
authors.lastname: Weng
authors.forename: Jin-Guang
authors.initials: JG
authors.lastname: Wu
mesh_terms: D016022:Case-Control Studies; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D004947:Esophagus / Q000378:metabolism*; D006801:Humans; D017550:Spectroscopy, Fourier Transform Infrared