title: Cytoskeletal regulation by Dictyostelium Ras subfamily proteins.
abstract: The Ras subfamily proteins are monomeric GTPases that function as molecular switches in cellular signal transduction. The roles of six of these proteins in regulating actin cytoskeletal functions in Dictyostelium discoideum are discussed in this review.
authors.affiliation: Department of Microbiology and Immunology, University of British Columbia, 300-6174 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z3.
authors.forename: Chinten James
authors.initials: CJ
authors.lastname: Lim
authors.forename: George B
authors.initials: GB
authors.lastname: Spiegelman
authors.forename: Gerald
authors.initials: G
authors.lastname: Weeks
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology; D003599:Cytoskeleton / Q000502:physiology*; D004023:Dictyostelium / Q000235:genetics / Q000502:physiology*; D017125:Genes, Protozoan; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment; D017384:Sequence Deletion; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D018631:ras Proteins / Q000235:genetics* / Q000378:metabolism*
chemical_list: D015800:Protozoan Proteins; D000242:Cyclic AMP; D018631:ras Proteins