Malaria transfection and transfection vectors.
Malaria remains a leading cause of death due to infectious disease. The completion of the Plasmodium falciparum genome sequencing project and release of preliminary proteomics data have significantly increased our understanding of the biology of this organism. Nonetheless, additional tools for functional analysis of this massive amount of information are now indispensable to further understand the basic biology of this parasite. The genetic manipulation of specific genes via the use of plasmid constructs and transfection represents one such tool.
Gardiner
Donald L
DL
Malaria Biology Laboratory, The Australian Centre for International and Tropical Health and Nutrition, a joint program of the Queensland Institute of Medical Research and the School of Population Health, University of Queensland, Herston. donG@qimr.edu.au
Skinner-Adams
Tina S
TS
Spielmann
Tobias
T
Trenholme
Katharine R
KR
D000818:Animals; D016054:DNA, Protozoan / Q000235:genetics; D018274:Electroporation; D018390:Gene Targeting / Q000379:methods; D005822:Genetic Vectors; D006801:Humans; D016778:Malaria, Falciparum / Q000635:transmission; D010963:Plasmodium falciparum / Q000235:genetics*; D014162:Transfection
D016054:DNA, Protozoan