[Cutaneous xanthomas associated with minocycline-induced cholestatic jaundice].
Minocycline is an effective treatment of acne vulgaris, especially for inflammatory forms. Prescription rates have increased in recent years accompanied by a number of reports concerning drug-induced side effects. An otherwise healthy woman developed an erythema multiform-like rash and and toxic hepatic damage causing cholestatic jaundice following long-term minocycline use. Unusual cutaneous lipid deposition also developed. Minocycline-induced side effects are reviewed.
Bamberg
C
C
Klinik und Poliklinik für Dermatologie und Venerologie der Universität Rostock.
Laskowski
J
J
Zimmermann
R
R
Gross
G
G
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D004892:Erythema Multiforme / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D041781:Jaundice, Obstructive / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D008099:Liver / Q000473:pathology; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D013997:Time Factors; D014973:Xanthomatosis / Q000175:diagnosis* / Q000473:pathology
D000900:Anti-Bacterial Agents; D008911:Minocycline
Xanthomatose der Haut bei cholestatischem Ikterus nach Minocyclin-Langzeittherapie.