Streptococcus pneumoniae endocarditis: persistence of DNA on heart valve material 7 years after infectious episode.
We amplified by PCR and sequenced Streptococcus pneumoniae rpoB from DNA of the cardiac valve of a man who had presented with pneumococcal endocarditis 7 years earlier. Histopathologically, the valve did not show evidence of endocarditis. This case raises the question of persistence of DNA without any evidence of infection.
Branger
S
S
Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Timone, Marseille, France.
Casalta
J P
JP
Habib
G
G
Collard
F
F
Raoult
D
D
D004269:DNA, Bacterial / Q000032:analysis*; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006351:Heart Valves / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D013296:Streptococcus pneumoniae / Q000235:genetics*; D013997:Time Factors
D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S; D012321:DNA-Directed RNA Polymerases; C105078:RNA polymerase beta subunit