Combination of xenon and isoflurane produces a synergistic protective effect against oxygen-glucose deprivation injury in a neuronal-glial co-culture model.
Ma
Daqing
D
Department of Anaesthetics and Intensive Care, Imperial College, London, UK.
Hossain
Mahmuda
M
Rajakumaraswamy
Nishanthan
N
Franks
Nicholas P
NP
Maze
Mervyn
M
D000465:Algorithms; D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D000818:Animals; D018920:Coculture Techniques; D004338:Drug Combinations; D004357:Drug Synergism; D005947:Glucose / Q000172:deficiency* / Q000502:physiology; D000860:Hypoxia / Q000473:pathology / Q000517:prevention & control*; D007530:Isoflurane / Q000494:pharmacology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D051379:Mice; D009457:Neuroglia / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D018696:Neuroprotective Agents / Q000494:pharmacology*; D014978:Xenon / Q000494:pharmacology*
D018685:Anesthetics, Inhalation; D004338:Drug Combinations; D018696:Neuroprotective Agents; D014978:Xenon; D007530:Isoflurane; D007770:L-Lactate Dehydrogenase; D005947:Glucose