title: Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime-Hawaii, 2001.
abstract: We report 4 urogenital Neisseria gonorrhoeae isolates recovered from 3 patients that demonstrated resistance to penicillin, tetracycline, and ciprofloxacin and reduced susceptibility to cefixime. This report of the first 3 patients in the United States identified with this multidrug-resistant strain may portend an emerging problem for clinicians and public health officials.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. Swang3@cdc.gov
authors.forename: Susan A
authors.initials: SA
authors.lastname: Wang
authors.forename: Maria Veneranda C
authors.initials: MV
authors.lastname: Lee
authors.forename: Norman
authors.initials: N
authors.lastname: O'Connor
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Iverson
authors.forename: Roy G
authors.initials: RG
authors.lastname: Ohye
authors.forename: Peter M
authors.initials: PM
authors.lastname: Whiticar
authors.forename: Judith A
authors.initials: JA
authors.lastname: Hale
authors.forename: David L
authors.initials: DL
authors.lastname: Trees
authors.forename: Joan S
authors.initials: JS
authors.lastname: Knapp
authors.forename: Paul V
authors.initials: PV
authors.lastname: Effler
authors.forename: Hillard S
authors.initials: HS
authors.lastname: Weinstock
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000494:pharmacology*; D020682:Cefixime / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005260:Female; D024841:Fluoroquinolones; D006069:Gonorrhea / Q000382:microbiology; D006254:Hawaii / Q000453:epidemiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010403:Penicillin Resistance
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D020682:Cefixime