Value of C-reactive protein in patients with stable angina pectoris, coronary narrowing (30% to 70%), and normal fractional flow reserve.
This study is the first that combines a serum marker of inflammation (C-reactive protein) and intracoronary-derived fractional flow reserve. A low C-reactive protein level was strongly associated with uncomplicated follow-up in patients with hemodynamic nonsignificant coronary lesions. These results show that C-reactive protein provides additional information relevant for clinical decision-making in patients with intermediate (30% to 70%) coronary lesions.
Meuwissen
Martijn
M
Department of Cardiology and Clinical Chemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. m.meuwissen@amc.uva.nl
de Winter
Robbert J
RJ
Chamuleau
Steven A J
SA
Heijne
Mechteld
M
Koch
Karel T
KT
van den Berg
Anja
A
van Straalen
Jan P
JP
Bax
Matthijs
M
Schorborgh
Carl E
CE
Kearney
Dermot
D
Sanders
Gerard T
GT
Tijssen
Jan G P
JG
Piek
Jan J
JJ
D000368:Aged; D000787:Angina Pectoris / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D001810:Blood Volume; D002097:C-Reactive Protein / Q000032:analysis*; D015331:Cohort Studies; D023921:Coronary Stenosis / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D012720:Severity of Illness Index
D002097:C-Reactive Protein