Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses.
Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs. Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.
Uhlig
Holm H
HH
Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Powrie
Fiona
F
D000818:Animals; D003713:Dendritic Cells / Q000502:physiology*; D006801:Humans; D018928:Immunity, Mucosal; D015212:Inflammatory Bowel Diseases / Q000276:immunology; D053759:Interleukin-23; D053760:Interleukin-23 Subunit p19; D007378:Interleukins / Q000096:biosynthesis*; D007422:Intestines / Q000276:immunology* / Q000382:microbiology*; D051379:Mice
C508840:IL23A protein, human; C508841:Il23a protein, mouse; D053759:Interleukin-23; D053760:Interleukin-23 Subunit p19; D007378:Interleukins