title: [Surgical treatment of giant cell tumor of bone].
abstract: BACKGROUND
  This study analyses a 5-year follow-up after treatment of giant cell tumour of bone during a 31-year period.
  
  
  METHODS
  Sixty patients with giant cell tumours of bone had been treated at the Centre for Musculoskeletal Tumours at Aarhus University Hospital. All patients were followed at regular intervals for 5-35 years, median = 11 years.
  
  
  RESULTS
  There were 54 benign giant cell tumours of bone, whereas six were classified as malignant. The most common location was around the knee. There were nine cases of recurrence. The 5-year recurrence-free survival was 77%. The lowest frequency of recurrence appeared after resection (6%) and the highest after bone-transplantation (22%).
  
  
  CONCLUSIONS
  The classical microscopic and macroscopic criteria for malignancy are not applicable for this rare tumour. All giant cell tumours of bone should be considered as potentially malignant, and therefore patients should be referred to a Centre for Musculoskeletal Tumours.
authors.affiliation: Arhus Universitetshospital, Arhus Kommunehospital, Ortopaedkirurgisk Afdeling E, Onkologisk Afdeling D og Radiologisk afdeling R.
authors.forename: Michael
authors.initials: M
authors.lastname: Davidsen
authors.forename: Johnny Ø
authors.initials: JØ
authors.lastname: Keller
authors.forename: Peter Holmberg
authors.initials: PH
authors.lastname: Jørgensen
authors.forename: Anne Grethe
authors.initials: AG
authors.lastname: Jurik
authors.forename: Ole Steen
authors.initials: OS
authors.lastname: Nielsen
authors.forename: Olaf Myhre
authors.initials: OM
authors.lastname: Jensen
mesh_terms: D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007717:Knee / Q000000981:diagnostic imaging; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011859:Radiography
vernacular_title: Kirurgisk behandling af kaempecelletumorer i knogler.