[Ischemic strokes in young adults].
OBJECTIVE
The incidence of cerebral ischemia occurring between 15 and 45 years of age is of 60 to 200 new cases per year per million inhabitants. The causes of cerebral ischemia consist of complications of atherosclerosis, cardio embolism, small-vessel occlusion, other determined causes and unknown causes. The breakdown of the causes differ from that of elderly subjects with a prominence of "unknown causes" and "other determined causes".


CONCLUSIONS
The association of a patent foramen ovale and an interatrioseptal aneurysm is a marker of an increased risk of recurrence. Cervical-artery dissections are the leading cause of cerebral ischemia in young adults and are usually associated with a good outcome in patients who survive the acute stage. Depending on the exhaustivity of the diagnostic work-up, 30 to 50% of cases have no clear cause. Mortality rate and recurrence rates in cerebral ischemia occurring in young adults are low. A negative diagnostic work-up is associated with a low risk of recurrence. Epilepsy is frequent. The incidence of cerebral ischemia occurring during pregnancies is 4,3 for 100,000 deliveries. Specific causes are led by eclampsia, and reversible angiopathies of the post partum period.


CONCLUSIONS
If the outcome is good, the causes are multiple and research should focus on the identification of new causes and the natural history in many of them.
Leys
D
D
Service de neurologie et pathologie neurovasculaire, équipe d'accueil EA 2691, hôpital Roger-Salengro, 59037 Lille cedex, France. dleys@chru-lille.fr
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001161:Arteriosclerosis / Q000150:complications; D002545:Brain Ischemia / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D003937:Diagnosis, Differential; D004617:Embolism / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications; D011379:Prognosis; D012008:Recurrence; D020521:Stroke / Q000209:etiology / Q000473:pathology* / Q000628:therapy
Les accidents ischémiques cérébraux du sujet jeune.