title: Case studies--arsenic.
abstract: Arsenic is found naturally in the environment. People may be exposed to arsenic by eating food, drinking water, breathing air, or by skin contact with soil or water that contains arsenic. In the U.S., the diet is a predominant source of exposure for the general population with smaller amounts coming from drinking water and air. Children may also be exposed to arsenic because of hand to mouth contact or eating dirt. In addition to the normal levels of arsenic in air, water, soil, and food, people could by exposed to higher levels in several ways such as in areas containing unusually high natural levels of arsenic in rocks which can lead to unusually high levels of arsenic in soil or water. People living in an area like this could take in elevated amounts of arsenic in drinking water. Workers in an occupation that involves arsenic production or use (for example, copper or lead smelting, wood treatment, pesticide application) could be exposed to elevated levels of arsenic at work. People who saw or sand arsenic-treated wood could inhale/ingest some of the sawdust which contains high levels of arsenic. Similarly, when pressure-treated wood is burned, high levels of arsenic could be released in the smoke. In agricultural areas where arsenic pesticides were used on crops the soil could contain high levels of arsenic. Some hazardous waste sites contain large quantities of arsenic. Arsenic ranks #1 on the ATSDR/EPA priority list of hazardous substances. Arsenic has been found in at least 1,014 current or former NPL sites. At the hazardous waster sites evaluated by ATSDR, exposure to arsenic in soil predominated over exposure to water, and no exposure to air had been recorded. However, there is no information on morbidity or mortality from exposure to arsenic in soil at hazardous waste sites. Exposure assessment, community and tribal involvement, and evaluation and surveillance of health effects are among the ATSDR future Superfund research program priority focus areas. Examples of exposures to arsenic in drinking water, diet and pesticide are given.
authors.affiliation: Agency for Toxic Substances and Disease Registry, Division of Toxicology, 1600 Clifton Road, NE, Atlanta, Georgia 30333, USA. cjc3@cdc.gov
authors.forename: C H Selene J
authors.initials: CH
authors.lastname: Chou
authors.forename: Christopher T
authors.initials: CT
authors.lastname: De Rosa
mesh_terms: D001151:Arsenic / Q000032:analysis; D020261:Arsenic Poisoning / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control; D001211:Asia, Western / Q000453:epidemiology; D002617:Chemical Industry; D004781:Environmental Exposure / Q000009:adverse effects* / Q000517:prevention & control; D005202:Asia, Eastern / Q000453:epidemiology; D006801:Humans; D014874:Water Pollutants, Chemical / Q000506:poisoning*; D014881:Water Supply / Q000592:standards; D014934:Wood
chemical_list: D014874:Water Pollutants, Chemical; D001151:Arsenic