[Real time monitor of rutin stability during heating by Fourier transform infrared spectroscopy].
The thermal stability of the natural product of rutin was studied by Fourier Transform Infrared Spectroscopy (FTIR) in this paper for the first time. To monitor the changing of rutin in real time, the temperature-control accessory was also used to in-situ follow the thermal behavior. It is demonstrated that as the temperature increased from 25 degrees C to 270 degrees C, the thermally-induced denaturation of rutin was accompanied by the oxidation and thermal discomposed procedure. The structure of rutin changed at a lower temperature (75 degrees C). This is not only indicating the existence of an intermediate state, but also approved that the stability of rutin is poor. While at the higher temperature (270 degrees C), rutin discomposed into two results. It is proved that this method is fast, accurate and having no solvent effect. Samples can thus be examined undestroyed.
Zhou
Q
Q
Department of Chemistry, Tsinghua University, 100084 Beijing.
Sun
S
S
Du
D
D
Liang
X
X
Yang
X
X
D003199:Computer Systems; D004355:Drug Stability; D006361:Heating; D015394:Molecular Structure; D012431:Rutin / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature
D012431:Rutin