Molecular biology and immunology.
OBJECTIVE
To review basic molecular biology and immunology concepts to provide a foundation for the understanding of current and developing biological treatments for cancer.


METHODS
Published scientific papers, review articles, and book chapters.


CONCLUSIONS
Research into the structure, functions of the human cell, and development of molecular biology techniques, has increased the understanding of cancer pathophysiology. This research has assisted scientists to develop new cancer treatments, collectively called biotherapies.


CONCLUSIONS
Oncology nurses are increasingly facing the administration of a variety of new biotherapies. Basic knowledge of molecular biology and immunology will assist the oncology nurse to understand the mechanisms of action of these therapies, leading to improved patient education and more vigilant surveillance of side effects during and after administration.
Mautner
Beatrice
B
Valley Radiotherapy Associates Medical Group, Vantage Oncology, Chatsworth, CA, USA.
Huang
David
D
D000222:Adaptation, Physiological; D000486:Allergy and Immunology / Q000193:education; D002454:Cell Differentiation; D002455:Cell Division; D022082:Cellular Structures; D004506:Education, Nursing; D006801:Humans; D007107:Immune System; D007113:Immunity, Innate; D008967:Molecular Biology / Q000193:education; D009859:Oncology Nursing; D019139:Tumor Escape