Colour coding in the primate retina: diverse cell types and cone-specific circuitry.
How is the trichromatic cone mosaic of Old World primates sampled by retinal circuits to create wavelength opponency? Red-green (L versus M cone) opponency appears to be mediated largely by the segregation of L versus M cone signals to the centre versus the surround of the midget ganglion cell receptive field, implying a complex cone type-specific wiring, the basis of which remains mysterious. Blue-yellow (S versus L+M cone) opponency is mediated by a growing family of low-density ganglion types that receive either excitatory or inhibitory input from S cones. Thus, the retinal circuits that underlie colour signalling in primates may be both more complex and more diverse then previously appreciated.
Dacey
Dennis M
DM
University of Washington, Department of Biological Structure & Washington National Primate Research Centre, HSC G514 Seattle, WA 98195-7420, USA. dmd@u.washington.edu
Packer
Orin S
OS
D000818:Animals; D003118:Color Perception / Q000502:physiology*; D006801:Humans; D009415:Nerve Net / Q000166:cytology / Q000502:physiology*; D011323:Primates; D012160:Retina / Q000166:cytology / Q000502:physiology*; D017949:Retinal Cone Photoreceptor Cells / Q000166:cytology / Q000502:physiology*; D014795:Visual Pathways / Q000166:cytology / Q000502:physiology*