title: Outbreak of serogroup C meningococcal disease caused by a variant of Neisseria meningitidis serotype 2a ET-15 in a community of men who have sex with men.
abstract: We describe an outbreak, in a community of men who have sex with men, of serogroup C meningococcal disease caused by a genetic variant of the serotype 2a ET-15 Neisseria meningitidis characterized by a point mutation in the gene coding for the serotype 2a antigen. A microbiological characterization of the outbreak strain is presented in this report.
authors.affiliation: National Microbiology Laboratory, Population and Public Health Branch, Health Canada Winnipeg, Manitoba, Canada. rtsang@hc-sc.gc.ca
authors.forename: Raymond S W
authors.initials: RS
authors.lastname: Tsang
authors.forename: Lori
authors.initials: L
authors.lastname: Kiefer
authors.forename: Dennis K S
authors.initials: DK
authors.lastname: Law
authors.forename: Jan
authors.initials: J
authors.lastname: Stoltz
authors.forename: Rita
authors.initials: R
authors.lastname: Shahin
authors.forename: Shirley
authors.initials: S
authors.lastname: Brown
authors.forename: Frances
authors.initials: F
authors.lastname: Jamieson
mesh_terms: D001483:Base Sequence; D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000209:etiology; D008969:Molecular Sequence Data; D009345:Neisseria meningitidis / Q000145:classification* / Q000235:genetics; D016133:Polymerase Chain Reaction; D012703:Serotyping
chemical_list: D004269:DNA, Bacterial