Fatty liver with elevated transaminase levels due to heterozygous apolipoprotein B deficiency.
Elevation of transaminase levels in asymptomatic subjects could be due to a common benign condition such as fatty liver or a more serious disease such as chronic hepatitis due to various causes; in some subjects a liver biopsy is indicated. Heterozygous apolipoprotein B deficiency is an uncommon cause of transaminase elevation, as indicated by low levels of cholesterol and low density lipoprotein-cholesterol. This should be noted to avoid unnecessary investigations (including liver biopsy) in asymptomatic subjects with persistent elevation of transminase levels in the serum.
Artekar
T M
TM
Department of Gastroenterology, Jaslok Hospital, Research Center, Mumbai.
Desai
H G
HG
D000328:Adult; D001055:Apolipoproteins B / Q000172:deficiency*; D005234:Fatty Liver / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D000637:Transaminases / Q000097:blood
D001055:Apolipoproteins B; D000637:Transaminases