title: [Current aspects of myopathology].
abstract: Advances in morphology, biochemistry and molecular genetics have been the basis of remarkable progress in the understanding of diseases of skeletal muscle during the last two decades. Many hereditary muscle diseases have been linked to specific gene defects. The functions of the respective proteins and the consequences of their mutations are now being characterized and correlated with the morphologically detectable muscle alterations. This review briefly summarizes the current state of knowledge of the pathogenesis of clinically relevant muscle diseases.
authors.affiliation: joachim.weis@pathology.unibe.ch
authors.forename: J
authors.initials: J
authors.lastname: Weis
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D015870:Gene Expression / Q000502:physiology; D006801:Humans; D008854:Microscopy, Electron; D009124:Muscle Proteins / Q000235:genetics; D018482:Muscle, Skeletal / Q000473:pathology; D009135:Muscular Diseases / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D011379:Prognosis
chemical_list: D009124:Muscle Proteins
vernacular_title: Aktuelle Aspekte der Myopathologie.