Volumetric intravascular ultrasound evidence that distal embolization during acute infarct intervention contributes to inadequate myocardial perfusion grade.
We studied 35 consecutive patients with myocardial infarction (MI) who were treated with direct infarct percutaneous coronary intervention (PCI) using standard angiographic (complete assessment of flow grade and blush grade) and pre- and post-PCI volumetric intravascular ultrasound analysis. Plaque reduction, which is evidence of distal embolization, contributes to inadequate tissue reperfusion in this lesion setting and supports the use of distal protection in the setting of an acute MI.
Kotani
Jun-ichi
J
Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA.
Mintz
Gary S
GS
Pregowski
Jerzy
J
Kalinczuk
Lukasz
L
Pichard
Augusto D
AD
Satler
Lowell F
LF
Suddath
William O
WO
Waksman
Ron
R
Weissman
Neil J
NJ
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D004617:Embolism / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D018084:Ultrasonography, Interventional