title: Membrane-associated CD40L and sCD40L in atherothrombotic disease.
abstract: Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.
authors.affiliation: The Zena and Michael A. Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York. USA.
authors.forename: Sunil X
authors.initials: SX
authors.lastname: Anand
authors.forename: Juan F
authors.initials: JF
authors.lastname: Viles-Gonzalez
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Badimon
authors.forename: Erdal
authors.initials: E
authors.lastname: Cavusoglu
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Marmur
mesh_terms: D001157:Arterial Occlusive Diseases / Q000097:blood / Q000209:etiology* / Q000473:pathology; D023201:CD40 Ligand / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D020782:Matrix Metalloproteinases / Q000378:metabolism; D010980:Platelet Membrane Glycoproteins / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction; D012995:Solubility; D013927:Thrombosis / Q000097:blood / Q000209:etiology* / Q000473:pathology
chemical_list: D010980:Platelet Membrane Glycoproteins; D023201:CD40 Ligand; D020782:Matrix Metalloproteinases