Clustering mass spectrometry data using order statistics.
Mass spectrometry data is inherently uncertain. Rather than compare peak heights across samples, a comparison can be made of the relative ordering of the peak height across samples. Order statistics are used to provide a distance metric between each ordered list of peak heights from the samples. A principal component analysis is performed on the set of distance vectors to highlight to important components.
Slotta
Douglas J
DJ
Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA. slotta@csgrad.cs.vt.edu
Heath
Lenwood S
LS
Ramakrishnan
Naren
N
Helm
Rich
R
Potts
Malcolm
M
D013058:Mass Spectrometry / Q000379:methods / Q000706:statistics & numerical data*; D010455:Peptides / Q000032:analysis*; D025341:Principal Component Analysis
D010455:Peptides