title: Mechanically stable implants of synthetic bone mineral by cold isostatic pressing.
abstract: A calcium phosphate phase that is equivalent in composition (carbonate content) and crystallinity (nanocrystals) to the mineral phase of bone was prepared by a continuous precipitation method. The powder was compacted by cold isostatic pressing into desired shapes with high compressive strength (range of 20-50 MPa, depending on the geometry). It is concluded that such implant materials can be prepared with a fine-tuned biodegradability in combination with a high mechanical strength. The high mechanical strength of the objects also permits further mechanical shaping procedures like drilling or cutting.
authors.affiliation: Solid State Chemistry, Faculty of Chemistry, University of Bochum, D-44780 Bochum, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Tadic
authors.forename: M
authors.initials: M
authors.lastname: Epple
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D003080:Cold Temperature; D019245:Compressive Strength; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D019736:Prostheses and Implants; D013314:Stress, Mechanical; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates; C020243:calcium phosphate