title: A study of the morphology of canine eyes enucleated or eviscerated due to complications following phacoemulsification.
abstract: This study was undertaken to describe the histopathologic abnormalities observed in canine eyes enucleated or eviscerated due to complications following phacoemulsification; to correlate these findings with the clinical abnormalities reported, and to suggest, if apparent, likely causes and effects of these abnormalities. Sixty-six canine globes or evisceration samples received for histopathologic interpretation over a 10-year period (1990-2000) were studied. All globes and evisceration samples were obtained from clinical patients examined by board-certified ophthalmologists. Hematoxylin and eosin (H&E) and alcian blue/periodic acid Schiff (PAS) stained sections were examined by light microscopy in every case. A tissue Gram stain was used when indicated. Clinical information obtained from the pathology submission form was reviewed in all cases, and obtained from questionnaires completed and returned by an ophthalmologist for 51 cases (77%). The most frequent histopathologic diagnoses were glaucoma (76%) and retinal detachment (64%). The most frequently reported clinical abnormalities in this series were glaucoma (86%) and uveitis (82%). Five problem areas were identified that appear to make a significant contribution to the failure of canine cataract surgery and merit further investigation: pre-iridal fibrovascular membranes; lens fiber regrowth; lens epithelial membranes; endophthalmitis, and the health of the corneal surgical incision.
authors.affiliation: The Queen Mother Hospital for Animals, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, UK. dmoore@rvc.ac.uk
authors.forename: Denise L
authors.initials: DL
authors.lastname: Moore
authors.forename: Gillian J
authors.initials: GJ
authors.lastname: McLellan
authors.forename: Richard R
authors.initials: RR
authors.lastname: Dubielzig
mesh_terms: D000818:Animals; D002386:Cataract / Q000662:veterinary; D004283:Dog Diseases / Q000453:epidemiology* / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D015353:Eye Enucleation / Q000706:statistics & numerical data / Q000662:veterinary*; D005260:Female; D008297:Male; D018918:Phacoemulsification / Q000706:statistics & numerical data / Q000662:veterinary*; D011183:Postoperative Complications / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D011795:Surveys and Questionnaires; D017211:Treatment Failure; D014922:Wisconsin / Q000453:epidemiology