[Planning and monitoring of autologous lymph vessel transplantation by means of nuclear medicine lymphoscintigraphy].
Autologous lymph vessel transplantation significantly improves the lymph drainage in patients with primary and secondary lymphedema. The aim of the present study was to prove whether scintigraphic long-term follow-up could demonstrate the function of autologous lymph vessels and the persisting success of this microsurgical technique respectively. In this study, visual and semiquantitative lymphoscintigraphy was used to prove the function of lymphatic vessel grafts in 20 patients comparing a preoperative baseline study with postoperative follow-up investigations once a year for a period of seven years. The reason for microsurgical lymph vessel transplantation was a primary (n = 4) or a secondary (n = 16) lymphedema. In 12 cases the transplantation site was at the upper extremity, in eight cases at the lower limb. In 17/20 patients lymphatic function significantly improved after autologous lymph vessel transplantation compared to the preoperative findings, as verified by visual improvement of lymph drainage and decrease of a numeric transport index. In 5/20 cases the vessel graft could be visualized directly. In these patients with scintigraphic visualization of the vessel graft, the transport index decreased to a significantly greater extent compared to the preoperative baseline study. 3/20 patients did not benefit from microsurgical treatment. Lymphoscintigraphy has shown to be an easy, reliable and readily available technique to assess lymphatic function on the long run. Scintigraphic visualization of the vessel graft showed a significantly better postoperative outcome than those without. The scintigraphic visualization of the vessel graft therefore seems to indicate a favourable prognosis regarding lymph drainage.
Weiss
M
M
Klinik und Poliklinik für Nuklearmedizin, Ludwig-Maximilians-Universität München, Germany. mayo.weiss@nuk.med.uni-muenchen.de
Baumeister
R G H
RG
Hahn
K
K
D000328:Adult; D000368:Aged; D001132:Arm / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg / Q000000981:diagnostic imaging / Q000601:surgery; D008196:Lymph / Q000502:physiology; D042601:Lymphatic Vessels / Q000000981:diagnostic imaging* / Q000637:transplantation*; D008209:Lymphedema / Q000000981:diagnostic imaging* / Q000601:surgery*; D008220:Lymphography; D061305:Lymphoscintigraphy; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D008991:Monitoring, Physiologic; D013997:Time Factors
Therapieplanung und Erfolgskontrolle der autologen Lymphgefäss-Transplantation mittels nuklearmedizinischer Lymphabflussszintigraphie.