title: Positron emission tomography in a patient with renal malacoplakia.
abstract: Positron emission tomography is increasingly used for the diagnosis of occult infection or malignancy. The altered metabolic rate of cells in areas of malignancy or infection provides a sensitive method to identify pathology that is otherwise not identified by standard imaging methods. This case report describes a patient who presented with a pyrexia of unknown origin and renal impairment. She had a positron emission tomography scan that showed intense accumulation of fluoro-deoxy-glucose in both kidneys. Subsequent renal biopsy results showed a diagnosis of malacoplakia, the treatment of which resulted in a resolution of the fever and a stabilization of renal function. This is the first report of the positron emission tomographic appearance of renal malacoplakia.
authors.affiliation: Renal Unit, Guy's and St Thomas' NHS Trust, London, England USA. neil.sheerin@kcl.ac.uk
authors.forename: Neil Stephen
authors.initials: NS
authors.lastname: Sheerin
authors.forename: Kirsti F
authors.initials: KF
authors.lastname: Bhatacharia
authors.forename: Michelle C
authors.initials: MC
authors.lastname: Webb
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D001205:Ascorbic Acid / Q000627:therapeutic use; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology; D019788:Fluorodeoxyglucose F18; D005767:Gastrointestinal Diseases / Q000209:etiology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D008287:Malacoplakia / Q000000981:diagnostic imaging*; D008875:Middle Aged; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed; D014295:Trimethoprim / Q000627:therapeutic use
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D014295:Trimethoprim; D001205:Ascorbic Acid