[Recurrent Kikuchi's disease in a patient with discoid lupus].
BACKGROUND
Histiocytic necrotizing lymphadenitis, also called Kikuchi-Fujimoto's disease (KD), usually occurs in young women and is characterized by localized lymphadenitis (mostly cervical) usually associated with fever. Diagnosis relies on histopathological and immunohistochemical analysis of involved lymph node. KD is considered to be the clinical expression of an inadequate immunological reaction, resulting in a self-limited hyperstimulation of the lymphoid tissue, trigerred by an antigenic infectious stimulation. The clinical course is usually benign with a spontaneous remission of symptoms. Recurrence is very rarely observed. KD may be associated with systemic lupus erythematosus, whereas the association with chronic discoid lupus has only been rarely reported.


METHODS
We report a case of KD recurrence, 9 years after the initial diagnosis, in a young eurasian woman, with a chronic discoid lupus erythematosus.


CONCLUSIONS
KD is a benign disease with a spontaneously good outcome. Recurrence may rarely occur many years after the initial diagnosis but needs a new histopathological confirmation. Systemic or even cutaneous lupus erythematosus may be associated with KD. Although unfrequent, this association suggests that both diseases could share a common pathogenesis.
Lecoules
S
S
Service de médecine interne, hôpital Henri-Mondor, 51, avenue du maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. aravinala@wanadoo.fr
Michel
M
M
Zarrouk
V
V
Gaulard
P
P
Schaeffer
A
A
Godeau
B
B
D000328:Adult; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000150:complications*; D011379:Prognosis; D012008:Recurrence
Maladie de Kikuchi récidivante chez une patiente atteinte de lupus discoïde.