title: Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised.
abstract: Studies of the broader autism phenotype, and of subtle changes in autism symptoms over time, have been compromised by a lack of established quantitative assessment tools. The Social Responsiveness Scale (SRS-formerly known as the Social Reciprocity Scale) is a new instrument that can be completed by parents and/or teachers in 15-20 minutes. We compared the SRS with the Autism Diagnostic Interview-Revised (ADI-R) in 61 child psychiatric patients. Correlations between SRS scores and ADI-R algorithm scores for DSM-IV criterion sets were on the order of 0.7. SRS scores were unrelated to I.Q. and exhibited inter-rater reliability on the order of 0.8. The SRS is a valid quantitative measure of autistic traits, feasible for use in clinical settings and for large-scale research studies of autism spectrum conditions.
authors.affiliation: Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. constantino@psychiatry.wustl.edu
authors.forename: John N
authors.initials: JN
authors.lastname: Constantino
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Davis
authors.forename: Richard D
authors.initials: RD
authors.lastname: Todd
authors.forename: Matthew K
authors.initials: MK
authors.lastname: Schindler
authors.forename: Maggie M
authors.initials: MM
authors.lastname: Gross
authors.forename: Susan L
authors.initials: SL
authors.lastname: Brophy
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Metzger
authors.forename: Christiana S
authors.initials: CS
authors.lastname: Shoushtari
authors.forename: Reagan
authors.initials: R
authors.lastname: Splinter
authors.forename: Wendy
authors.initials: W
authors.lastname: Reich
mesh_terms: D020817:Asperger Syndrome / Q000175:diagnosis* / Q000523:psychology; D001321:Autistic Disorder / Q000175:diagnosis* / Q000523:psychology; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000523:psychology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011594:Psychometrics; D015203:Reproducibility of Results; D012919:Social Behavior