Associations between plasma natriuretic peptide levels, symptoms, and left ventricular function in patients with chronic aortic regurgitation.
In 40 patients with chronic moderate to severe aortic regurgitation, brain natriuretic peptide, N-brain natriuretic peptide, and atrial natriuretic peptide were higher in symptomatic patients compared with asymptomatic patients after adjustment for age, gender, and ejection fraction, but each natriuretic peptide correlated weakly with echocardiographic measures of left ventricular size and function. In patients with chronic aortic regurgitation, measurement of natriuretic peptide levels may provide information on left ventricular function in addition to echocardiography.
Gerber
Ivor L
IL
Cardiology Department, Green Lane Hospital, Auckland 1030 32, New Zealand.
Stewart
Ralph A H
RA
French
John K
JK
Legget
Malcolm E
ME
Greaves
Sally C
SC
West
Teena M
TM
Kerr
Andrew J
AJ
Richards
A Mark
AM
White
Harvey D
HD
D000328:Adult; D001022:Aortic Valve Insufficiency / Q000097:blood* / Q000150:complications* / Q000000981:diagnostic imaging; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002908:Chronic Disease; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000097:blood* / Q000000981:diagnostic imaging / Q000209:etiology*
D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor