Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer.
A score based on the combination of the systemic inflammatory response and albumin hazards ratio (HR) 1.70, 95% CI 1.23 - 2.35, P=0.001) was comparable in prognostic value to that based on stage and performance status (HR 1.48, 95% CI 1.12 - 1.95, P=0.006) in patients with inoperable non-small-cell lung cancer. The former is simple to measure and well standardised.
Forrest
L M
LM
University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK.
McMillan
D C
DC
McArdle
C S
CS
Angerson
W J
WJ
Dunlop
D J
DJ
D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis; D000418:Albumins / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002097:C-Reactive Protein / Q000032:analysis*; D002289:Carcinoma, Non-Small-Cell Lung / Q000097:blood / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000175:diagnosis; D005260:Female; D006801:Humans; D034141:Hypoalbuminemia / Q000150:complications; D007249:Inflammation; D017567:Karnofsky Performance Status; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies
D000418:Albumins; D014408:Biomarkers, Tumor; D002097:C-Reactive Protein