Gene therapy: theoretical and bioethical concepts.
Gene therapy holds great promise. Somatic gene therapy has the potential to treat a wide range of disorders, including inherited conditions, cancers, and infectious diseases. Early progress has already been made in the treatment of a range of disorders. Ethical issues surrounding somatic gene therapy are primarily those concerned with safety. Germline gene therapy is theoretically possible but raises serious ethical concerns concerning future generations.
Smith
Kevin R
KR
School of Contemporary Sciences, University of Abertay Dundee, Dundee, Scotland, UK. mltkrs@tay.ac.uk
D000256:Adenoviridae / Q000235:genetics; D000293:Adolescent; D001675:Bioethics; D002467:Cell Nucleus / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D000229:Dependovirus / Q000235:genetics; D018274:Electroporation; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000941:ethics / Q000379:methods*; D005822:Genetic Vectors; D005854:Germ Cells; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000628:therapy; D019076:Transgenes
D004247:DNA