title: Darkened Xenopus tadpoles appeared with neurochemical agents.
abstract: Skin darkened tadpoles sometimes appear spontaneously. Darkened was artificially induced in Xenopus larvae by yohimbine or chlorpromazine. These phenomena look like that are seen at pinealectomized or hypothalamus separated Xenopus larva. In this experiment, such a morphological color changed Xenopus larva is suggested by cause of inhibition of alpha2-adrenargic receptor or dopamine receptor from gastrula stages.
authors.affiliation: Department of Biochemistry, Hamamatsu University, School of Medicine, Hamamatsu-shi, Handa-chou 1-20-1, 431-3192, Japan. satoeij1@hama-med.ac.jp
authors.forename: Eiji
authors.initials: E
authors.lastname: Sato
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Shibata
authors.forename: Yi-Xin
authors.initials: YX
authors.lastname: Wu
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Uezato
authors.forename: Katsumi
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miura
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D010858:Pigmentation; D011954:Receptors, Dopamine / Q000502:physiology; D014981:Xenopus / Q000196:embryology*; D015016:Yohimbine / Q000494:pharmacology*
chemical_list: D000317:Adrenergic alpha-Antagonists; D018492:Dopamine Antagonists; D011954:Receptors, Dopamine; D015016:Yohimbine; D002746:Chlorpromazine