title: Is objective cure of mild undifferentiated incontinence more readily achieved than that of moderate incontinence? Costs and 2-year outcome.
abstract: Because the prognostic value of 1-h pad testing has received scant attention, we tested the hypothesis that mild incontinence of any etiology is more readily cured than moderate incontinence. A consecutive series of 150 patients with mild (2-9.9 g) to moderate (10-49.9 g) incontinence (as judged by weight gain on 1-h pad testing) [1] attending a urogynecology unit were recruited, of whom 145 completed all baseline objective measures: 110 completed 12 weeks of conservative therapy, with follow-up data at 2 years available for 51 subjects. At 12 weeks 81% of 'mild' patients became 'dry' on the 1-h pad test versus 36.8% in the moderate group (chi2<0.0001). Interestingly the post-treatment changes seen in all other outcomes demonstrated equally positive responses for the mild and moderate groups. At 2-year follow-up 29/71 (40.8%) of patients with mild incontinence and 22/74 (29.7%) of patients with moderate incontinence were satisfied and had no requirement for further therapy, the remainder having sought other treatments (chi2=1.963 P=0.161). Of the responders, (11/29) (37.9%) of mildly incontinent patients and (8/22 (36.4%)) of moderately affected subjects remained continent (on 20-point incontinence score < or =2 m, chi2=0.013, P=0.9087). Improvements in quality of life persisted to an equal degree in both groups.
authors.affiliation: The Pelvic Floor Unit, St George Hospital, University of New South Wales, Sydney, Australia.
authors.forename: R
authors.initials: R
authors.lastname: O'Sullivan
authors.forename: A
authors.initials: A
authors.lastname: Simons
authors.forename: S
authors.initials: S
authors.lastname: Prashar
authors.forename: P
authors.initials: P
authors.lastname: Anderson
authors.forename: M
authors.initials: M
authors.lastname: Louey
authors.forename: K H
authors.initials: KH
authors.lastname: Moore
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D003365:Costs and Cost Analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016496:Incontinence Pads; D008875:Middle Aged; D009042:Motivation; D017063:Outcome Assessment, Health Care; D017773:Pelvic Floor; D012720:Severity of Illness Index; D013997:Time Factors; D014550:Urinary Incontinence, Stress / Q000175:diagnosis / Q000191:economics* / Q000628:therapy*; D014563:Urodynamics