A family of Xenopus BTB-Kelch repeat proteins related to ENC-1: new markers for early events in floorplate and placode development.
We report the expression of a family of Xenopus genes encoding BTB-Kelch repeat proteins related to mouse ENC-1. Xenopus ENC-related-1 (Xencr-1) is expressed throughout the dorsal midline in dorsal endoderm, notochord, and deep neuroectoderm cells during early neurula stages. Later, Xencr-1 expression is downregulated in the notochord in an anterior-to-posterior progression but is maintained in the floorplate and dorsal endoderm. Xencr-3 is expressed strongly in several cranial placodes during the early neurula stages, placing it among the earliest molecular markers of placode precursor populations.
Haigo
Saori L
SL
Department of Molecular and Cell Biology, 401 Barker Hall #3204, University of California, Berkeley, CA 94720-3204, USA.
Harland
Richard M
RM
Wallingford
John B
JB
D000595:Amino Acid Sequence; D000818:Animals; D004475:Ectoderm / Q000378:metabolism; D004625:Embryo, Nonmammalian; D004707:Endoderm / Q000378:metabolism; D005775:Gastrula / Q000378:metabolism; D005819:Genetic Markers; D006801:Humans; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000235:genetics / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014981:Xenopus / Q000196:embryology*; D029867:Xenopus Proteins / Q000235:genetics / Q000378:metabolism*
D005819:Genetic Markers; D008840:Microfilament Proteins; D009479:Neuropeptides; D009687:Nuclear Proteins; D029867:Xenopus Proteins; C112302:ectodermal-neural cortex 1 protein