title: Langerhans cells - dendritic cells of the epidermis.
abstract: Langerhans cells (LC) are dendritic cells of the epidermis. They are highly specialized leukocytes that serve immunogenic and tolerogenic purposes. Here, we review some aspects of LC biology, emphasizing those areas where LC are or may turn out to be special.
authors.affiliation: Department of Dermatology, University of Innsbruck, Innsbruck, Austria. nikolaus.romani@uibk.ac.at
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Romani
authors.forename: Sandra
authors.initials: S
authors.lastname: Holzmann
authors.forename: Christoph H
authors.initials: CH
authors.lastname: Tripp
authors.forename: Franz
authors.initials: F
authors.lastname: Koch
authors.forename: Patrizia
authors.initials: P
authors.lastname: Stoitzner
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000276:immunology; D015703:Antigens, CD; D000954:Antigens, Surface / Q000276:immunology; D002465:Cell Movement / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology; D000078404:Epidermal Cells; D004817:Epidermis / Q000276:immunology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000166:cytology / Q000276:immunology* / Q000648:ultrastructure; D037181:Lectins, C-Type / Q000276:immunology; D037241:Mannose-Binding Lectins; D051379:Mice
chemical_list: D015703:Antigens, CD; D000954:Antigens, Surface; C121916:CD207 protein, human; C498497:Cd207 protein, mouse; D037181:Lectins, C-Type; D037241:Mannose-Binding Lectins