title: Association of myocardial viability on nitrate-augmented technetium-99m hexakis-2-methoxylisobutyl isonitrile myocardial tomography and intermediate-term outcome in patients with prior myocardial infarction and left ventricular dysfunction.
abstract: Seventy-eight patients with prior myocardial infarction and left ventricular dysfunction who underwent nitrate-augmented myocardial tomography were followed for 23 +/- 14 months. Event-free survival was 100% in 34 patients with myocardial viability who underwent coronary artery bypass grafting (CABG) and 53% in those who received medical therapy (p = 0.0008). Of the 44 patients without myocardial viability, event-free survival was not significantly different between patients who underwent CABG and those who received medical therapy (96% vs 90%, p = NS).
authors.affiliation: Department of Nuclear Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 167 Bei Li Shi Lu, Beijing 100 037, China. zxhe@btamail.net.cn
authors.forename: Zuo-Xiang
authors.initials: ZX
authors.lastname: He
authors.forename: Min-Fu
authors.initials: MF
authors.lastname: Yang
authors.forename: Xiu-Jie
authors.initials: XJ
authors.lastname: Liu
authors.forename: Rong-Fang
authors.initials: RF
authors.lastname: Shi
authors.forename: Run-Lin
authors.initials: RL
authors.lastname: Gao
authors.forename: Sheng-Shou
authors.initials: SS
authors.lastname: Hu
authors.forename: Qing-Yu
authors.initials: QY
authors.lastname: Wu
authors.forename: Yue-Jin
authors.initials: YJ
authors.lastname: Yang
authors.forename: Ji-Lin
authors.initials: JL
authors.lastname: Chen
mesh_terms: D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D009566:Nitrates; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011379:Prognosis; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D017256:Technetium Tc 99m Sestamibi; D013997:Time Factors; D014022:Tissue Survival / Q000502:physiology*; D015899:Tomography, Emission-Computed, Single-Photon; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*
chemical_list: D009566:Nitrates; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi