title: Haemorrhagic bullae in a case of paroxysmal nocturnal haemoglobinuria.
abstract: Paroxysmal nocturnal haemoglobinuria is a clonal stem cell disorder manifesting as haemolysis, bone marrow failure and thrombosis. We report a rare cutaneous manifestation on the trunk of a 40-year-old patient. Skin biopsy revealed the presence of fibrin thrombi in the capillaries. The eruption responded within days after commencing oral corticosteroids.
authors.affiliation: Department of Dermatology, King's College Hospital, London, UK. jonathanmlwhite@hotmail.com
authors.forename: J M L
authors.initials: JM
authors.lastname: White
authors.forename: K
authors.initials: K
authors.lastname: Watson
authors.forename: R
authors.initials: R
authors.lastname: Arya
authors.forename: A W P
authors.initials: AW
authors.lastname: du Vivier
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology* / Q000473:pathology