From disease to development to cell biology and back.
Nowadays, the focus of developmental studies is shifting away from formal models of developmental pathways that are characterised by flow charts of controlling factors connected by arrows, to mechanistic models that explain developmental processes at the cellular level. Surprisingly, this shift towards a cellular view of developmental biology is occurring simultaneously across a range of model organisms. One consequence of taking such a cell biological view of development is that many model organisms are now becoming good models for studies of human disease and therapy.
Gonzalez-Gaitan
Marcos
M
Max-Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.
D000818:Animals; D002468:Cell Physiological Phenomena; D003094:Collagen / Q000378:metabolism; D015509:Developmental Biology; D006801:Humans; D007365:Intercellular Junctions / Q000378:metabolism; D007797:Laminin / Q000378:metabolism; D008563:Membrane Lipids / Q000378:metabolism; D009024:Morphogenesis / Q000502:physiology
D007797:Laminin; D008563:Membrane Lipids; D003094:Collagen