title: Language lateralization by Wada test and fMRI in 100 patients with epilepsy.
abstract: Comparing the determination of language dominance using fMRI with results of the Wada test in 100 patients with different localization-related epilepsies, the authors found 91% concordance between both tests. The overall rate of false categorization by fMRI was 9%, ranging from 3% in left-sided temporal lobe epilepsy (TLE) to 25% in left-sided extratemporal epilepsy. Language fMRI might reduce the necessity of the Wada test for language lateralization, especially in TLE.
authors.affiliation: Mara Hospital and Institute for Interdisciplinary Epilepsy Research, Bethel Epilepsy Centre, Bielefeld, Germany. fgw@mara.de
authors.forename: F G
authors.initials: FG
authors.lastname: Woermann
authors.forename: H
authors.initials: H
authors.lastname: Jokeit
authors.forename: R
authors.initials: R
authors.lastname: Luerding
authors.forename: H
authors.initials: H
authors.lastname: Freitag
authors.forename: R
authors.initials: R
authors.lastname: Schulz
authors.forename: S
authors.initials: S
authors.lastname: Guertler
authors.forename: M
authors.initials: M
authors.lastname: Okujava
authors.forename: P
authors.initials: P
authors.lastname: Wolf
authors.forename: I
authors.initials: I
authors.lastname: Tuxhorn
authors.forename: A
authors.initials: A
authors.lastname: Ebner
mesh_terms: D000328:Adult; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007806:Language Disorders / Q000175:diagnosis* / Q000473:pathology; D007807:Language Tests; D008279:Magnetic Resonance Imaging; D008297:Male