Synthesis of 1-substituted-6-methyluracils.
A series of 6-methyl-1H-pyrimidin-2,4-diones bearing different substituents in the 1-position of the uracil ring were prepared starting from substituted ureas and diketene.
Nieto
Rosa Maria
RM
Laboratorio de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Farmacia, Universidade de Santiago de Compostela, Spain.
Coelho
Alberto
A
Martínez
Ana
A
Stefanachi
Angela
A
Sotelo
Eddy
E
Raviña
Enrique
E
D002855:Chromatography, Thin Layer; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014498:Uracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D007202:Indicators and Reagents; D014498:Uracil