title: [Acute local reaction to intra-articular infiltration with synvisc (Hylan GF20). About two cases].
abstract: A second stage in the treatment of arthrosis following the non-steroid anti-inflammatories is formed by the so-called chondroprotectors and intraarticular viscosupplementation with hyaluronic acid, generally in the knee. Although infrequent, cases have been described of transitory inflammatory arthritis following intra-articulary administration. The main problem is differential diagnosis with a septic secondary arthritis and its consequences. This is a generally benign process with a still unknown transitory aetiology with different hypotheses, but which involves suspension of the treatment. We present two cases that resolved the sequels with different moments of appearance, the first in the three hours following infiltration, and the second four days later.
authors.affiliation: Cirugía Ortopédica y Traumatología, Hospital García Orcoyen, 31200 Estella, Spain. enoainsa@cfnavarra.es
authors.forename: E
authors.initials: E
authors.lastname: Noáin
authors.forename: J J
authors.initials: JJ
authors.lastname: Sáncez-Villares
authors.forename: P J
authors.initials: PJ
authors.lastname: Lasanta
authors.forename: F J
authors.initials: FJ
authors.lastname: González Arteaga
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D007249:Inflammation / Q000139:chemically induced* / Q000628:therapy; D007270:Injections, Intra-Articular / Q000009:adverse effects*; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: C049816:hylan; D006820:Hyaluronic Acid
vernacular_title: Reacción aguda local tras infiltración intraarticular con Synvisc (Hylan GF 20). A propósito de dos casos.