Successful pregnancy in a woman with congenital "Swiss-cheese" platelets. A case report.
BACKGROUND
Congenital "Swiss-cheese" platelets are a rare disorder of platelet function due to impaired calcium mobilization. Management of pregnancy in patients with this disorder had not been reported previously.


METHODS
Successful pregnancy occurred in a woman with congenital Swiss-cheese platelets. Neither the mother nor neonate experienced any hemorrhagic complications.


CONCLUSIONS
Successful pregnancy is possible in women with congenital Swiss-cheese platelets. The lack of hemorrhagic complications may be due to the increase in platelet intracellular free calcium concentration during pregnancy.
Chan
Louis Yik-Si
LY
Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. lyschan@cuhk.edu.hk
Leung
Tse Ngong
TN
D000328:Adult; D001791:Blood Platelet Disorders / Q000150:complications / Q000503:physiopathology*; D002128:Calcium Metabolism Disorders / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000503:physiopathology*; D011256:Pregnancy Outcome; D013997:Time Factors