title: Slapped cheek disease. How it affects children and pregnant women.
abstract: BACKGROUND
  Slapped cheek disease, otherwise known as erythema infectiosum (EI) or 'fifth disease', is a common cause of fever and rash in children.
  
  
  OBJECTIVE
  The clinical features in children, and the implications for pregnant contacts will be discussed in this article.
  
  
  CONCLUSIONS
  Erythema infectiosum is usually a mild self limiting illness in children. Patients are unlikely to be infectious after the rash and other symptoms are present, and children do not need to be excluded from school or childcare. Infection in pregnant women under 20 weeks gestation can lead to miscarriage or hydrops, but in 50% of cases the fetus is unaffected. Pregnant women who are IgM positive require appropriate specialist referral and serial ultrasounds.
authors.affiliation: Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria.
authors.forename: Alexis
authors.initials: A
authors.lastname: Frydenberg
authors.forename: Mike
authors.initials: M
authors.lastname: Starr
mesh_terms: D002648:Child; D016731:Erythema Infectiosum / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000628:therapy*; D012307:Risk Factors