title: Chlorocoulometric determination of primaquine.
abstract: A method for the coulometric determination of primaquine is presented. The coulometric titration is carried out in the anode compartment, in the supporting electrolyte consisting of 0.5 M sulfuric acid and 0.2 M sodium chloride solution, in the presence of methyl orange as indicator. The electrogenerated chlorine reacts with primaquine in a 2:1 molar stoichiometric ratio. Accurate and reproducible results have been obtained in the assay of small amounts of primaquine. One coulomb corresponds to 1.1797 mg of primaquine diphosphate.
authors.affiliation: Department of Analytical Chemistry, Faculty of Natural Science, Charles University Prague, Czechoslovakia.
authors.forename: A
authors.initials: A
authors.lastname: Berka
authors.forename: K
authors.initials: K
authors.lastname: Nikolić
authors.forename: K
authors.initials: K
authors.lastname: Velasević
mesh_terms: D000962:Antimalarials / Q000032:analysis*; D002713:Chlorine / Q000737:chemistry; D004563:Electrochemistry; D007202:Indicators and Reagents; D011319:Primaquine / Q000031:analogs & derivatives / Q000032:analysis*; D015203:Reproducibility of Results
chemical_list: D000962:Antimalarials; D007202:Indicators and Reagents; D002713:Chlorine; D011319:Primaquine