Antituberculous therapy-induced toxicity.
Antituberculous drugs are generally safe but can occasionally be associated with life-threatening complications. This is a case report of neurotoxicity, acute respiratory distress syndrome (ARDS) and drug fever, occurring in a patient after initiation of antituberculous therapy (ATT).
Bharat
A
A
Department of Medicine, Unit-1 and Infectious Diseases, Christian Medical College and Hospital, Vellore.
Vedkumar
M
M
Subhash
H S
HS
Abraham
O C
OC
Mathai
D
D
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005334:Fever / Q000139:chemically induced; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D011718:Pyrazinamide / Q000009:adverse effects* / Q000627:therapeutic use; D012128:Respiratory Distress Syndrome / Q000139:chemically induced*; D012640:Seizures / Q000139:chemically induced*; D014401:Tuberculosis, Urogenital / Q000188:drug therapy*
D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid