title: Pathologic study of acute toxoplasmosis in experimental animals.
abstract: We studied the pathology of acute toxoplasmosis in experimental mice inoculated with RH strain tachyzoites of Toxoplasma gondii. All died from severe disseminated toxoplasmosis involving the liver, spleen and pancreas. Pathological features of acute toxoplasmosis in susceptible mice could be regarded as an excellent model for acute reactivation of Toxoplasma in the immunosuppressed host.
authors.affiliation: Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. tmymv@mahidol.ac.th
authors.forename: Yaowalark
authors.initials: Y
authors.lastname: Sukthana
authors.forename: Phuangphet
authors.initials: P
authors.lastname: Waree
authors.forename: Emsri
authors.initials: E
authors.lastname: Pongponratn
authors.forename: Urai
authors.initials: U
authors.lastname: Chaisri
authors.forename: Mario
authors.initials: M
authors.lastname: Riganti
mesh_terms: D000208:Acute Disease; D000818:Animals; D051379:Mice; D008854:Microscopy, Electron; D014122:Toxoplasma / Q000472:pathogenicity*; D014124:Toxoplasmosis, Animal / Q000473:pathology*