Ligand-free Heck reaction: Pd(OAc)2 as an active catalyst revisited.
Palladium acetate was shown to be an extremely active catalyst for the Heck reaction of aryl bromides. Both the base and the solvent were found to have a fundamental influence on the efficiency of the reaction, with K(3)PO(4) and N,N-dimethylacetamide being the optimal base and solvent, respectively.
Yao
Qingwei
Q
Department of Chemistry and Biochemistry, The Michael Faraday Laboratories, Northern Illinois University, DeKalb, Illinois 60115-2862, USA. qyao@niu.edu
Kinney
Elizabeth P
EP
Yang
Zhi
Z