[Synergic effect in mechanical and pharmacologic treatments of acute coronary syndromes].
Percutaneous coronary intervention procedures are currently preferred for the treatment of Acute Coronary Syndromes. Given the relevance of platelets and fibrin formation in the physiopathology of these clinical syndromes and in the genesis of possible complications caused by interventionist procedures, their association with the use of drugs to control the thrombogenic and clotting response has led to a significant reduction of recurring infarcts, deaths, and re-interventions of the treated vessel or emergency surgery. Due to their synergic effects with percutaneous coronary interventions, aspirin, clopidogrel, heparins (fractionated and non-fractionated), and platelet receptor IIb/IIIa blockers have become an important part of the therapeutics in Ischemic Coronary Syndromes.
Gil Moreno
Manuel
M
Instituto Nacional de Cardiología Ignacio Chávez INCICH, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, 14080 México, D. F. gil@cardiologia.org.mx
D000208:Acute Disease; D000077144:Clopidogrel; D003131:Combined Modality Therapy; D003324:Coronary Artery Disease / Q000628:therapy*; D003328:Coronary Thrombosis / Q000628:therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D013577:Syndrome; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D006493:Heparin; D000077144:Clopidogrel; D013988:Ticlopidine
Efecto sinérgico entre los tratamientos mecánico y farmacológico de los síndromes coronarios agudos.