Liver failure in a child receiving highly active antiretroviral therapy and voriconazole.
We describe a 10-year-old child with vertically transmitted acquired immunodeficiency syndrome who was receiving antiretroviral combination therapy and died of liver failure after beginning voriconazole therapy.
Scherpbier
Henriette J
HJ
Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands. h.j.scherpbier@amc.uva.nl
Hilhorst
Michaela I
MI
Kuijpers
Taco W
TW
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D019380:Anti-HIV Agents / Q000009:adverse effects*; D000935:Antifungal Agents / Q000009:adverse effects*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D017093:Liver Failure / Q000139:chemically induced*; D011743:Pyrimidines / Q000009:adverse effects*; D014230:Triazoles / Q000009:adverse effects*; D065819:Voriconazole
D019380:Anti-HIV Agents; D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole