title: Effects of the MEK inhibitor CI-1040 (PD 184352) on progenitor growth from normal and myelodysplastic marrow.
authors.forename: David P
authors.initials: DP
authors.lastname: Steensma
authors.forename: Ruben A
authors.initials: RA
authors.lastname: Mesa
authors.forename: Terra L
authors.initials: TL
authors.lastname: Reeder
authors.forename: Ayalew
authors.initials: A
authors.lastname: Tefferi
authors.forename: Scott H
authors.initials: SH
authors.lastname: Kaufmann
mesh_terms: D001549:Benzamides / Q000494:pharmacology*; D001853:Bone Marrow / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology / Q000502:physiology; D018922:HL-60 Cells; D006412:Hematopoietic Stem Cells / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology / Q000502:physiology; D006801:Humans; D020929:Mitogen-Activated Protein Kinase Kinases / Q000037:antagonists & inhibitors*; D009190:Myelodysplastic Syndromes / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D014407:Tumor Cells, Cultured
chemical_list: C120227:2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide; D001549:Benzamides; D020929:Mitogen-Activated Protein Kinase Kinases