title: Gene therapy: theoretical and bioethical concepts.
abstract: Gene therapy holds great promise. Somatic gene therapy has the potential to treat a wide range of disorders, including inherited conditions, cancers, and infectious diseases. Early progress has already been made in the treatment of a range of disorders. Ethical issues surrounding somatic gene therapy are primarily those concerned with safety. Germline gene therapy is theoretically possible but raises serious ethical concerns concerning future generations.
authors.affiliation: School of Contemporary Sciences, University of Abertay Dundee, Dundee, Scotland, UK. mltkrs@tay.ac.uk
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Smith
mesh_terms: D000256:Adenoviridae / Q000235:genetics; D000293:Adolescent; D001675:Bioethics; D002467:Cell Nucleus / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D000229:Dependovirus / Q000235:genetics; D018274:Electroporation; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000941:ethics / Q000379:methods*; D005822:Genetic Vectors; D005854:Germ Cells; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000628:therapy; D019076:Transgenes
chemical_list: D004247:DNA