Dermatoglyphs and gastric cancer.
Gastric cancer is very common malignant disease, etiology of which is still unknown. Some studies consider that it is caused by a joint activity of both genetic and environmental factors. Digito-palmar dermatoglyphs were already used to determine hereditary base of some malignant diseases (breast, lung and colorectal cancer) and it was the reason for investigations of the correlation of their quantity features at patients with gastric cancer (36 males and 32 females) and the control groups of phenotypically healthy persons (50 males and 50 females). By performing statistical data processing of the multivariate and univariate analysis, as well as of discriminant ones, it was possible to prove the existence of heterogeneity between the investigated groups. Higher incidence of gastric cancer and the blood group A could be confirmed, as well. From the obtained findings can be concluded, that the results of quantitative analysis of digitopalmar dermatoglyphs affirm the existence of genetic predisposition for development of gastric cancer.
Zivanović-Posilović
Gordana
G
Anesthesiology Department, General Hospital Dr. Ivo Pedisić, Sisak, Croatia.
Milicić
Jasna
J
Bozicević
Dubravko
D
D000230:Adenocarcinoma / Q000235:genetics* / Q000503:physiopathology*; D000328:Adult; D001789:Blood Group Antigens; D003878:Dermatoglyphics / Q000145:classification*; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D015999:Multivariate Analysis; D013274:Stomach Neoplasms / Q000235:genetics* / Q000503:physiopathology*
D001789:Blood Group Antigens