Ebola virus: from discovery to vaccine.
Ebola virus, being highly pathogenic for humans and non-human primates and the subject of former weapons programmes, is now one of the most feared pathogens worldwide. In addition, the lack of pre- and post-exposure interventions makes the development of rapid diagnostics, new antiviral agents and protective vaccines a priority for many nations. Further insight into the ecology, immunology and pathogenesis of Ebola virus will promote the delivery of these urgently required tools.
Feldmann
Heinz
H
Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada. heinz_feldmann@hc-sc.gc.ca
Jones
Steven
S
Klenk
Hans-Dieter
HD
Schnittler
Hans-Joachim
HJ
D000818:Animals; D029043:Ebolavirus / Q000276:immunology*; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D006801:Humans; D008252:Macaca fascicularis; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines