title: [The investigation of tracheas transplantation by wrapping in a muscle flap].
abstract: OBJECTIVE
  To investigate the possibility of tracheas transplantation by wrapping it in a muscle flap.
  
  
  METHODS
  With a dog model, a number of tracheas were separately wrapped in the unilateral sternocephalic muscle flap and the bilateral sternohyoid-sternothyroid muscle flap, and placed in the original site. The tracheas autografting was used as a control. The viability was evaluated by the examination of fiberoptic bronchoscopy, histopathology and microangiography, the measurement of tracheal mucosal blood flow and the calculation of survival rate and percentage of patency.
  
  
  RESULTS
  The submucosal blood flow of the transplanted tracheas was detected in the unilateral sternocephalic muscle flap group and the bilateral sternohyoid-sternothyroid muscle flap group 1 week after the surgery and gradually reached the level close to the normal in 4 weeks, while the vascular ingrowth was also shown from the wrapped muscle flap into the transplanted tracheas by using a microangiography technique. The histopathological examination demonstrated that the structure of the transplanted tracheas was quite same as the original one and its inner surface was also covered with pseudostratified columnar ciliary epithelia. However, in the control group, the mucous membranes turned black one week after the transplantation and all dogs died from the graft necrosis.
  
  
  CONCLUSIONS
  The tracheas wrapped in a muscular flap could survive well for a long time.
authors.affiliation: Plastic Surgery Hospital, Chinese Academy of Medical Science, Beijing 100041, China.
authors.forename: Lian-zhao
authors.initials: LZ
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Zhou
authors.forename: Fei
authors.initials: F
authors.lastname: Fan
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: Bin-bin
authors.initials: BB
authors.lastname: Li
authors.forename: Guo-bin
authors.initials: GB
authors.lastname: Cai
authors.forename: Fu-shan
authors.initials: FS
authors.lastname: Xue
authors.forename: Jie
authors.initials: J
authors.lastname: Luan
authors.forename: Chuan-de
authors.initials: CD
authors.lastname: Zhou
authors.forename: Fan-hui
authors.initials: FH
authors.lastname: Meng
authors.forename: Pei-tao
authors.initials: PT
authors.lastname: Wnag
authors.forename: Hua-bing
authors.initials: HB
authors.lastname: Wang
mesh_terms: D000818:Animals; D004285:Dogs; D004848:Epithelium; D006085:Graft Survival / Q000502:physiology*; D009336:Necrosis / Q000401:mortality; D012039:Regional Blood Flow / Q000502:physiology; D013524:Surgical Flaps / Q000098:blood supply / Q000473:pathology; D013997:Time Factors; D014132:Trachea / Q000098:blood supply / Q000473:pathology / Q000637:transplantation*; D014182:Transplantation, Autologous