Shaping and stretching life by autophagy.
In a recent study published in Science, demonstrate that genes required for autophagy act downstream of insulin-like signaling, and are involved in the expression of major life history traits, including dauer larva development and adult life span.
Riddle
Donald L
DL
Molecular Biology Program, University of Missouri-Columbia, 311 Tucker Hall, Columbia, MO 65211, USA.
Gorski
Sharon M
SM
D000818:Animals; D001343:Autophagy / Q000502:physiology*; D017173:Caenorhabditis elegans; D029742:Caenorhabditis elegans Proteins / Q000502:physiology; D007328:Insulin / Q000502:physiology*; D007814:Larva; D034741:RNA, Small Interfering / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D033921:Vesicular Transport Proteins; D015003:Yeasts
D029742:Caenorhabditis elegans Proteins; D007328:Insulin; D034741:RNA, Small Interfering; D033921:Vesicular Transport Proteins; C477268:bec-1 protein, C elegans