Importance of esophagogastroduodenoscopy in the evaluation of non-gastrointestinal mucosa-associated lymphoid tissue lymphoma.
OBJECTIVE
Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma that most commonly presents in the gastrointestinal (GI) tract. However, it can present in non-GI primary sites. This study was conducted to determine the incidence of gastric involvement in non-GI presentation of MALT lymphoma.


METHODS
We retrospectively reviewed the medical records of 36 consecutive patients who presented with non-GI MALT lymphoma and had EGD as a part of the initial staging work-up between 1992 and 2001.


RESULTS
The median age was 62 years (range, 27-82); 27 were female patients. The frequency of the primary site was; salivary gland/parotid gland (N = 14), ocular adnexa (N = 7), lung (N = 3), oral cavity (N = 3), skin (N = 3), thyroid (N = 2), nasopharynx (N = 2), larynx (N = 1), breast (N = 1). Twelve patients were found to have gastric involvement; 2 additional patients progressed in the stomach 5 and 6 months later, respectively.


CONCLUSIONS
Routine evaluation of the stomach should be a part of the initial staging work-up of non-GI MALT lymphoma.
Dabaja
Bouthaina S
BS
Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Ha
Chul S
CS
Wilder
Richard B
RB
Pro
Barbara
B
McLaughlin
Peter
P
Cabanillas
Fernando
F
Cox
James D
JD
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016145:Endoscopy, Digestive System / Q000379:methods; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies