title: Results of kidney transplantation in recipients over 70 years of age: experience at a single center.
abstract: We performed 41 kidney transplants in patients >70 years (35 single and 6 dual), with a mean recipient age of 72+/-2 years, from January 1990 to December 2001. Mean age of the donors was 69+/-12 years. Immunosuppression used triple therapy with steroids, mycophenolate mofetil, and cyclosporine or tacrolimus. Cold ischemia time was 23+/-3 hours. The incidence of primary nonfunction was 4.8%, and delayed graft function 58.5%. Acute rejection incidence was 12%. The actuarial patient survival rates at 12, 24, and 36 months were 82.5%, 82.5%, and 75%, respectively. Actuarial survival rates of the grafts censuring for death of the recipient with a functioning graft were 89.5%, 86%, and 68%, respectively. Nine of the 18 graft losses were due to recipient death. Overall, renal transplant recipients >70 years showed good results. The principal cause of graft loss was recipient death.
authors.affiliation: Nephrology Service, Hospital 12 de Octubre, Madrid, Spain.
authors.forename: J C
authors.initials: JC
authors.lastname: Herrero
authors.forename: E
authors.initials: E
authors.lastname: Gutiérrez
authors.forename: A
authors.initials: A
authors.lastname: Martínez
authors.forename: E
authors.initials: E
authors.lastname: González
authors.forename: E
authors.initials: E
authors.lastname: Morales
authors.forename: M A
authors.initials: MA
authors.lastname: Muñoz
authors.forename: M
authors.initials: M
authors.lastname: Valentín
authors.forename: B
authors.initials: B
authors.lastname: Bueno
authors.forename: M
authors.initials: M
authors.lastname: Praga
authors.forename: E
authors.initials: E
authors.lastname: Hernández
authors.forename: J M
authors.initials: JM
authors.lastname: Morales
authors.forename: J L
authors.initials: JL
authors.lastname: Rodicio
authors.forename: A
authors.initials: A
authors.lastname: Andrés
mesh_terms: D000368:Aged; D002102:Cadaver; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000401:mortality / Q000502:physiology*; D012189:Retrospective Studies; D015996:Survival Rate; D014019:Tissue Donors; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents