Organogenesis: keeping in touch with the germ cells.
DE-cadherin and its novel regulator, the transmembrane protein Fear of Intimacy, have been found to control the adhesive interactions between germline and somatic cells that lead to gonad formation in Drosophila.
Godt
Dorothea
D
Department of Zoology, University of Toronto, 25 Harbord Street, M5S 3G5, Toronto, Ontario, Canada. dgrodt@zoo.utoronto.ca
Tepass
Ulrich
U
D000818:Animals; D015820:Cadherins / Q000378:metabolism* / Q000502:physiology; D002448:Cell Adhesion / Q000235:genetics / Q000502:physiology*; D004330:Drosophila; D029721:Drosophila Proteins / Q000378:metabolism*; D005854:Germ Cells / Q000502:physiology*; D006066:Gonads / Q000196:embryology*; D008565:Membrane Proteins / Q000378:metabolism*; D038081:Organogenesis / Q000502:physiology*
D015820:Cadherins; D029721:Drosophila Proteins; D008565:Membrane Proteins; C478568:foi protein, Drosophila