title: Experimental infection of recent field isolates of feline herpesvirus type 1.
abstract: Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical symptoms were observed on cats infected with the isolates 00-015 and 00-035 compared with those of C7301-infected cats. Severe ocular lesions including conjunctivitis were found in the cats infected with the isolates, indicating that the recent FHV-1 has a potential to induce severe FVR symptoms including ocular lesions.
authors.affiliation: Faculty of Agriculture, Yamaguchi University, Yoshida, Yamaguchi, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Hamano
authors.forename: Ken
authors.initials: K
authors.lastname: Maeda
authors.forename: Fuminori
authors.initials: F
authors.lastname: Mizukoshi
authors.forename: Yumi
authors.initials: Y
authors.lastname: Une
authors.forename: Masami
authors.initials: M
authors.lastname: Mochizuki
authors.forename: Yukinobu
authors.initials: Y
authors.lastname: Tohya
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Akashi
authors.forename: Kazushige
authors.initials: K
authors.lastname: Kai
mesh_terms: D000818:Animals; D001831:Body Temperature; D001835:Body Weight; D002371:Cat Diseases / Q000503:physiopathology / Q000821:virology*; D002415:Cats; D003231:Conjunctivitis / Q000662:veterinary / Q000821:virology; D006470:Hemorrhage / Q000662:veterinary / Q000821:virology; D006566:Herpesviridae Infections / Q000503:physiopathology / Q000662:veterinary*; D013997:Time Factors; D018140:Varicellovirus / Q000302:isolation & purification / Q000472:pathogenicity*