title: Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment.
abstract: Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. Four of the 10 patients were positive for CMV.
authors.affiliation: Neurophysiopathology Unit, IRCCS E. Medea, Bosisio Parini, LC, Italy. zucca@bp.lnf.it
authors.forename: C
authors.initials: C
authors.lastname: Zucca
authors.forename: S
authors.initials: S
authors.lastname: Binda
authors.forename: R
authors.initials: R
authors.lastname: Borgatti
authors.forename: F
authors.initials: F
authors.lastname: Triulzi
authors.forename: L
authors.initials: L
authors.lastname: Radice
authors.forename: C
authors.initials: C
authors.lastname: Buttè
authors.forename: P E
authors.initials: PE
authors.lastname: Barkhaus
authors.forename: M
authors.initials: M
authors.lastname: Barbi
mesh_terms: D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology; D002675:Child, Preschool; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009421:Nervous System Malformations / Q000175:diagnosis; D012189:Retrospective Studies