Imiquimod 5% cream for keloid management.
BACKGROUND
Keloid treatment represents a therapeutic challenge. New adjuvant therapy is needed to reduce the high recurrence rate (50%) of excised keloids.


OBJECTIVE
To describe the method for using imiquimod 5% cream in the prevention of keloid recurrence after surgery.


METHODS
This is a review of the scientific rationale and clinical experience of using imiquimod 5% cream for keloid management.


CONCLUSIONS
Topical application of imiquimod 5% cream after surgery reduces keloid recurrences.
Berman
Brian
B
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, FL 33136, USA. bberman@med.miami.edu
Villa
Adriana
A
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant / Q000379:methods; D006801:Humans; D000077271:Imiquimod; D007627:Keloid / Q000188:drug therapy* / Q000517:prevention & control* / Q000601:surgery; D055502:Secondary Prevention; D013514:Surgical Procedures, Operative
D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D000077271:Imiquimod