Prevalence of fragilysin gene in Bacteroides fragilis isolates from blood and other extraintestinal samples.
Of 166 Bacteroides fragilis isolates, 26.2% of 103 isolates from blood and 20.6% of 63 extraintestinal isolates harbored the fragilysin gene (difference not statistically significant). Clinical characteristics and evolution were comparable in patients with B. fragilis bacteremia with or without this enterotoxin. Fragilysin seems not to be an important virulence factor in B. fragilis disease.
Foulon
Ina
I
Department of Microbiology, Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium.
Piérard
Denis
D
Muyldermans
Gaëtan
G
Vandoorslaer
Kristof
K
Soetens
Oriane
O
Rosseel
Paul
P
Lauwers
Sabine
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000382:microbiology*; D001441:Bacteroides fragilis / Q000235:genetics* / Q000472:pathogenicity; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008666:Metalloendopeptidases / Q000235:genetics*; D008875:Middle Aged; D037521:Virulence Factors
D037521:Virulence Factors; D008666:Metalloendopeptidases; C091198:fragilysin