Idiopathic thrombocytopenic purpura and mononeuropathy multiplex.
Peripheral neuropathy is an uncommon complication of idiopathic thrombocytopenic purpura (ITP). We report a 61-year-old man with ITP who developed acute-onset mononeuropathy multiplex. An electrophysiologic study revealed active axonal degenerative alteration, and a sural nerve biopsy showed axonal degeneration. Intraneural hemorrhage was suggested to be the most likely cause.
Ijichi
Toshiharu
T
Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan. tijichi@koto.kpu-m.ac.jp
Muranishi
Manabu
M
Shimura
Kazuo
K
Inaba
Toru
T
Fujita
Naohisa
N
Oka
Nobuyuki
N
Nakagawa
Masanori
M
D000208:Acute Disease; D001369:Axons / Q000473:pathology; D002196:Capillaries / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D020422:Mononeuropathies / Q000150:complications* / Q000473:pathology; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*