title: Medication use and falls in community-dwelling older persons.
abstract: BACKGROUND
  The association between injurious falls requiring a visit to the emergency department and various classes of medications was examined in a case-control study of community living persons aged 66 years and older.
  
  
  METHODS
  Administrative databases from an urban health region provided the information used. Five controls for each case were randomly selected from community dwelling older persons who had not reported an injurious fall to one of the six regional emergency departments in the study year. Two series of analyses on medication use within 30 days of the fall were conducted using logistic regression, the first controlling for age, sex, and median income, the second controlling for co-morbid diagnoses as well.
  
  
  RESULTS
  During the study year there were 2,405 falls reported by 2,278 individuals to six regional emergency departments giving a crude fall rate of 31.6 per 1,000 population per year. The initial analysis identified seven medication classes that were associated with an increased risk of an injurious fall, while controlling for age, gender and income. However, with further analyses controlling for the additional effects of co-morbid disease, narcotic pain-killers (odds ratio 1.68), anti-convulsants (odds ratio 1.51) and anti-depressants (odds ratio 1.46) were significant independent predictors of sustaining an injurious fall.
  
  
  CONCLUSIONS
  These results are based on a Canadian population-based study with a large community sample. The study found that taking certain medications were independent predictors of sustaining an injurious fall in our elderly population - in addition to the risk associated with their medical condition.
authors.affiliation: Community Health, University of Northern British Columbia, 3333 University Way, Prince George, BC, Canada, V2N 4Z9. kellyk@unbc.ca
authors.forename: Karen D
authors.initials: KD
authors.lastname: Kelly
authors.forename: Will
authors.initials: W
authors.lastname: Pickett
authors.forename: N
authors.initials: N
authors.lastname: Yiannakoulias
authors.forename: Brian H
authors.initials: BH
authors.lastname: Rowe
authors.forename: Don P
authors.initials: DP
authors.lastname: Schopflocher
authors.forename: Larry
authors.initials: L
authors.lastname: Svenson
authors.forename: Don C
authors.initials: DC
authors.lastname: Voaklander
authors.forename: Kaven D
authors.initials: KD
authors.lastname: Kelly
mesh_terms: D000058:Accidental Falls; D000368:Aged; D000416:Alberta; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D002170:Canada; D016022:Case-Control Studies; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012111:Residence Characteristics; D012307:Risk Factors
chemical_list: D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents