An introduction to lymphocyte and viral dynamics: the power and limitations of mathematical analysis.
Mathematics is a useful tool in the analysis and understanding of population dynamic aspects of the immune response. However, the power of mathematical modelling in immunology is frequently limited by the shortage of experimental data. Here, we review the contribution of mathematics to two areas of immunology. We highlight the problem caused by lack of knowledge of the system, which can greatly restrict the use of mathematics and lead to errors caused by model-specific results.
Asquith
Becca
B
Department of Immunology, Wright-Fleming Institute, Imperial College, London W2 1PG, UK. b.asquith@imperial.ac.uk
Bangham
Charles R M
CR
D008214:Lymphocytes / Q000276:immunology*; D008962:Models, Theoretical; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D019562:Viral Load; D014780:Viruses / Q000276:immunology*