A rare cause of pituitary stalk enlargement and panhypopituitarism.
Pituitary stalk involvement is seen in a variety of medical conditions such as infectious diseases, infiltrative diseases and tumors (intracranial and metastatic). Metastatic cancer has a greater propensity to involve the infundibulum and neurohypophysis. We report a case of a 68-year-old man who presented with thickening of the stalk, panhypopituitarism, diabetes insipidus and generalized lymphadenopathy. Lymphoma was diagnosed on axillary lymph node biopsy and lymphomatous involvement of the infundibulum was suspected. Although infundibular thickening resolved and diabetes insipidus improved after chemotherapy, panhypopituitarism persisted.
Basaria
Shehzad
S
Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue, B-Building, Suite 114, Baltimore, MD 21224, USA. sbasaria@jhmi.edu
Krop
Julie S
JS
Braga-Basaria
Milena
M
D000236:Adenoma / Q000150:complications* / Q000473:pathology; D000368:Aged; D003919:Diabetes Insipidus / Q000150:complications; D017809:Fatal Outcome; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000473:pathology; D008297:Male; D010902:Pituitary Gland / Q000473:pathology*