[Mineral fibers and bladder cancer. Morphological and minerological investigations in a subject without professional exposure].
It is confirmed that occupational and paraoccupational exposure to mineral fibres, particularly asbestos fibres, plays a fundamental role in the induction of lung cancer and pleural mesothelioma. The possible association with other human cancers (e.g. larynx cancer, gastro-intestinal cancer, uro-genital cancer and emolinfopoietic cancer) is not yet demonstrated, even if some mineral fibres are identified in tissues different from the lung ones, such as kidney, bladder, and some biological fluids (e.g. urine of subjects with occupational exposure to asbestos). The possibility of damage caused to tissues in consequence of exposure to low concentration of mineral fibres (e.g. environmental exposure) has still to be defined. In this work we report the results of a mineralogical study by means of scanning electron microscopy with microprobe of a case of bladder cancer in a subject without professional exposure to mineral fibres where asbestos bodies are identified by optical microscopy.
Bellis
D
D
Centro Interdipartimentale per lo Studio degli Amianti e di altri Particolati Nocivi G. Scansetti, Università degli Studi di Torino. donata.bellis@aslto4.it
Belluso
E
E
Capella
S
S
Coverlizza
S
S
Ferraris
G
G
D017632:Asbestos, Serpentine / Q000009:adverse effects* / Q000032:analysis; D002295:Carcinoma, Transitional Cell / Q000209:etiology* / Q000648:ultrastructure; D004781:Environmental Exposure; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D019016:Mineral Fibers / Q000032:analysis; D017640:Silicates / Q000009:adverse effects* / Q000032:analysis; D013048:Specimen Handling; D001749:Urinary Bladder Neoplasms / Q000209:etiology* / Q000648:ultrastructure
D017632:Asbestos, Serpentine; D019016:Mineral Fibers; D017640:Silicates
Fibre minerali e carcinoma vescicale. Indagine morfologica e mineralogica in un soggetto non professionalmente esposto.