title: Orphan anticancer drug rejected.
authors.forename: Adrian
authors.initials: A
authors.lastname: Burton
mesh_terms: D000818:Animals; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D004149:Dioxoles / Q000627:therapeutic use*; D015507:Drugs, Investigational; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D007880:Legislation, Drug; D009965:Orphan Drug Production / Q000331:legislation & jurisprudence*; D044005:Tetrahydroisoquinolines; D000077606:Trabectedin; D014481:United States; D014486:United States Food and Drug Administration / Q000331:legislation & jurisprudence
chemical_list: D018906:Antineoplastic Agents, Alkylating; D004149:Dioxoles; D015507:Drugs, Investigational; D007546:Isoquinolines; D044005:Tetrahydroisoquinolines; D000077606:Trabectedin