title: A hybrid breast biopsy system combining ultrasound and MRI.
abstract: System design and initial phantom accuracy results for a novel biopsy system integrating both magnetic resonance (MR) and ultrasound (US) imaging modalities are presented. A phantom experiment was performed to investigate the efficacy of this hybrid guidance biopsy technique in a breast tissue mimicking phantom. A comparison between MR-guided core biopsy verses MR/US-guided core biopsy of phantom targets was realized using a scoring system based on the consistency of the acquired core samples (14 gauge). It was determined that the addition of US to guide needle placement improved the accuracy from an average score of 7.4 out of 10 (MRI guidance alone), to 9.6 (MRI/US guidance) over 21 trials. The average amount of needle tip correction resulting from the additional US information was determined to be 3.7 mm. This correction value is substantial, equal to approximately one radius of the intended targets. Hybrid US/MRI guided biopsy appears to offer a simple means to ensure accurate breast tissue sampling without the need for repeat MRI scans for verification or the need for real-time imaging in open MRI geometries.
authors.affiliation: Department of Medical Biophysics, Sunnybrook and Women's College Health Science Centre, University of Toronto, Toronto, ON M4N 3M5, Canada.
authors.forename: C A
authors.initials: CA
authors.lastname: Piron
authors.forename: P
authors.initials: P
authors.lastname: Causer
authors.forename: R
authors.initials: R
authors.lastname: Jong
authors.forename: R
authors.initials: R
authors.lastname: Shumak
authors.forename: D B
authors.initials: DB
authors.lastname: Plewes
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods*; D001940:Breast / Q000033:anatomy & histology* / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000295:instrumentation / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique / Q000295:instrumentation*; D016217:Ultrasonography, Mammary / Q000295:instrumentation* / Q000379:methods