title: [On-demand treatment with gastric acid inhibitors for gastroesophageal reflux disease].
abstract: Gastric acid inhibitors are effective and safe drugs for the treatment of gastro-oesophageal reflux disease. Since reflux disease is frequent in Western populations, the use of gastric acid inhibitors leads to a considerable financial burden to the community. However, a large proportion of the patients with reflux symptoms do not take their medication continuously but use the drugs as required by their symptoms. This opens the possibility of a more cost-effective approach in which optimal symptom relief is achieved in combination with cost reduction. The type of on-demand therapy must be based on the individual pattern of reflux symptoms. In this approach, the patient determines the actual therapy whereas the physician functions as advisor. It is presently unknown whether any adverse effects result from the long-term on-demand therapy of reflux disease.
authors.affiliation: Leids Universitair Medisch Centrum, afd. Maag-, Darm- en Leverziekten, Postbus 9600, 2300 RC Leiden. cbhwlamers@lumc.nl
authors.forename: C B
authors.initials: CB
authors.lastname: Lamers
mesh_terms: D000863:Antacids / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D005744:Gastric Acid / Q000378:metabolism*; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006635:Histamine H2 Antagonists / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D006801:Humans; D054328:Proton Pump Inhibitors; D012449:Safety; D016896:Treatment Outcome
chemical_list: D000863:Antacids; D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors
vernacular_title: Zuurremming op maat voor patiënten met gastro-oesofageale reflux.