title: Leucovorin (calcium folinate) in "antifreeze" poisoning.
abstract: A short cut review was carried out to establish whether the addition of intravenous calcium folinate to standard (ethanol) therapy reduced the visual complications of antifreeze (methanol and ethyleny glycol). Altogether 12 papers were found using the reported search, of which one animal study presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of this best paper are tabulated. A clinical bottom line is stated.
authors.affiliation: Emergency Department, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
authors.forename: Angaj
authors.initials: A
authors.lastname: Ghosh
authors.forename: Russell
authors.initials: R
authors.lastname: Boyd
mesh_terms: D000818:Animals; D000931:Antidotes / Q000627:therapeutic use*; D005026:Ethylene Glycols / Q000506:poisoning*; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D008297:Male
chemical_list: D000931:Antidotes; D005026:Ethylene Glycols; D002955:Leucovorin