Breakthroughs in cancer gene therapy.
OBJECTIVE
To give oncology nurses an overview on the vectors and selected approaches used in the current clinical trials involving gene transfer to cancer patients.


METHODS
Peer-reviewed scientific papers, review articles, and book chapters.


CONCLUSIONS
Significant progress has been made in the field of cancer gene therapy. Different phases of clinical protocols derived from new generations of vectors and novel approaches are being tested for use in the treatment of patients with cancer.


CONCLUSIONS
Oncology nurses need to be familiar with current advances in the field of cancer gene therapy to expand their role as health care professional, patient educator, and advocate for the treatment of patients with cancer.
Liu
Ke
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Surgery Branch, Center for Cancer Research, National Institutes of Health, 9000 Rockville Pike, Bldg 10, Room 2B08, Bethesda, MD 20892-1502, USA.
D002986:Clinical Trials as Topic; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods / Q000451:nursing* / Q000639:trends*; D006801:Humans; D016233:Immunotherapy, Active / Q000451:nursing; D016219:Immunotherapy, Adoptive / Q000451:nursing; D009369:Neoplasms / Q000451:nursing / Q000628:therapy; D024802:Nurse's Role; D009859:Oncology Nursing; D014161:Transduction, Genetic