title: Late-onset diffuse lamellar keratitis.
abstract: BACKGROUND
  Diffuse lamellar keratitis (DLK) is marked by the presence of diffuse or multifocal infiltrates confined to the laser in situ keratomileusis (LASIK) interface. These infiltrates are culture-negative, and the etiology is thought to be noninfectious. Most cases of DLK occur within the first week or 2 following surgery.
  
  
  METHODS
  We described 2 cases of DLK that occurred 3 months after LASIK. These patients were treated with intensive topical corticosteroids.
  
  
  RESULTS
  Treatment with topical corticosteroid was instituted, with rapid improvement in patient symptoms, visual acuity, and slit-lamp biomicroscopic findings.
  
  
  CONCLUSIONS
  DLK may occur as late as 3 months after LASIK.
authors.affiliation: Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
authors.forename: Rie
authors.initials: R
authors.lastname: Amano
authors.forename: Koji
authors.initials: K
authors.lastname: Ohno
authors.forename: Kimiya
authors.initials: K
authors.lastname: Shimizu
authors.forename: Masanobu
authors.initials: M
authors.lastname: Suzuki
authors.forename: Daisuke
authors.initials: D
authors.lastname: Aizawa
authors.forename: Mari
authors.initials: M
authors.lastname: Komatsu
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones