Cycloheptadiene ring synthesis by tandem intermolecular enyne metathesis.
[reaction: see text] The tandem intermolecular enyne metathesis between 1-alkynes and cyclopentene is reported, providing 2-substituted 1,3-cycloheptadienes. The success of the intermolecular reaction hinges on an appropriate balance between cycloalkene ring strain and reactivity of the alkyne.
Kulkarni
Amol A
AA
Department of Chemistry, University at Buffalo, the State University of New York, Amherst, New York 14260, USA.
Diver
Steven T
ST
D000466:Alkadienes / Q000138:chemical synthesis*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003508:Cycloheptanes / Q000138:chemical synthesis*; D003517:Cyclopentanes / Q000737:chemistry; D006838:Hydrocarbons; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature
D000466:Alkadienes; D000480:Alkynes; D003508:Cycloheptanes; D003517:Cyclopentanes; D006838:Hydrocarbons; C030011:carbene; D012428:Ruthenium; D008697:Methane