Screening of volunteer students in Yaounde (Cameroon, Central Africa) for Chlamydia trachomatis infection and genotyping of isolated C. trachomatis strains.
The prevalence of Chlamydia trachomatis infection was 3.78% out of 1,277 volunteer students screened by direct fluorescence assay and Cobas Amplicor PCR. The infection was associated with the nonuse or inconsistent use of condoms in women (P = 0.026) and a previous sexually transmitted infection in men (P = 0.023). The most frequent genotypes determined by sequencing the omp1 genes of 25 clinical isolates were E (44%) and F (20%), and some strains harbored mutations, but E genotype strains did not.
Ngandjio
Antoinette
A
Centre Pasteur du Cameroun, Yaounde, Cameroon. Laboratoire de Bactériologie, Centre National de Référence des Infections à Chlamydia, Université de Bordeaux II, Bordeaux, France.
Clerc
Maithe
M
Fonkoua
Marie Christine
MC
Thonnon
Jocelyn
J
Njock
Friede
F
Pouillot
Regis
R
Lunel
Françoise
F
Bebear
Christiane
C
De Barbeyrac
Bertille
B
Bianchi
Anne
A
D000328:Adult; D002163:Cameroon / Q000453:epidemiology; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D002692:Chlamydia trachomatis / Q000145:classification* / Q000302:isolation & purification; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D018272:Porins / Q000737:chemistry / Q000235:genetics; D015995:Prevalence; D012307:Risk Factors
D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis