Identification of a novel DRB1*04 allele: DRB1*0445.
The novel allele DRB1*0445 differs from DRB1*04051 by a single nucleotide substitution at codon 23 (CGG-->CCG), resulting in an amino-acid change from arginine to proline. The haplotype associated with the novel allele is A*2402-B*5401-Cw*0102-DRB1*0445-DRB4*01-DQB1*0302.
Bae
S-C
SC
Department of Internal Medicine, Division of Rheumatology, Hanyang University College of Medicine, Seoul, Korea.
Lee
K W
KW
D000328:Adult; D000368:Aged; D005260:Female; D014644:Genetic Variation; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D008297:Male; D008875:Middle Aged; D017354:Point Mutation
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains