[Physiology of immune response genes].
In addition to performing its major physiological function--a control of the immune response, the major gene complex: HLA system, also maintains a human genetic diversity. The latter provides optimal conditions for survival of human being as species. We submit modern data on genome and proteome mechanisms which are principal for maintenance of these functions.
Khaitov
R M
RM
Institute of Immunology, Moscow, 115478, 24 Kashirskoe Shosse, Building 2, Russia.
Alekseev
L P
LP
D000818:Animals; D005802:Genes, MHC Class II / Q000502:physiology*; D006680:HLA Antigens / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D006648:Histocompatibility; D006801:Humans; D008958:Models, Molecular; D011110:Polymorphism, Genetic
D006680:HLA Antigens
Fiziologiia genov immunnogo otveta.