title: [Hyperthyrotropinemia in Mexican newborns].
abstract: OBJECTIVE
  To assess the differences in the blood concentration levels of the thyroid stimulating hormone and their possible use as an indicator of iodine sufficiency, in a sample of Mexican newborns.
  
  
  METHODS
  A cross-sectional study was conducted from September 1999 to August 2000, among 25,427 Mexican newborns in the Ministry of Health clinics from 5 states. A total of 8,095 heel-prick and 17,332 umbilical cord blood samples were analyzed. Blood samples were collected in filter paper and processed by enzyme-linked immunosorbent assay. The Mann-Whitney U test and the Kruskal-Wallis test were used for statistical analyses.
  
  
  RESULTS
  Hyperthyrotropinemia was found in 9.95% of heel samples and in 24.27% of umbilical cord samples (TSH > 5 microUl/ml).
  
  
  CONCLUSIONS
  The percentage of hyperthyrotropinemia observed in this study was higher than that expected in a population with sufficient iodine intake; these findings could be due to poor maternal iodine intake.
authors.affiliation: Instituto Nacional de Pediatría, México, DF, México. amieva@servidor.unam.mx
authors.forename: Marcela
authors.initials: M
authors.lastname: Vela-Amieva
authors.forename: Crescencio
authors.initials: C
authors.lastname: Hernández-Osorio
authors.forename: Salvador
authors.initials: S
authors.lastname: Gamboa-Cardiel
authors.forename: Claudia R
authors.initials: CR
authors.lastname: González-Contreras
authors.forename: Martha Elva
authors.initials: ME
authors.lastname: Pérez-Andrade
authors.forename: Joel
authors.initials: J
authors.lastname: Ortiz-Cortés
authors.forename: Blanca E
authors.initials: BE
authors.lastname: Aguirre-Vélez
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood* / Q000175:diagnosis / Q000517:prevention & control; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D015997:Neonatal Screening; D013972:Thyrotropin / Q000097:blood / Q000172:deficiency*
chemical_list: D013972:Thyrotropin
vernacular_title: Hipertirotropinemia en recién nacidos mexicanos.