title: Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype.
abstract: In patients with hypertension who have the DD-ACE genotype (higher angiotensin-converting enzyme [ACE] activity), plasma levels of angiotensin-(1-7) are 4 times lower than in patients with the II-ACE genotype (lower ACE levels). Angiotensin II levels are similar in both groups.
authors.affiliation: Department of Cardiovascular Diseases, Medical School, Pontifica Catholic University of Chile, Marcoleta 367, Room 19, Santiago, Chile. jjalil@med.puc.cl
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Jalil
authors.forename: Cristián
authors.initials: C
authors.lastname: Palomera
authors.forename: María Paz
authors.initials: MP
authors.lastname: Ocaranza
authors.forename: Iván
authors.initials: I
authors.lastname: Godoy
authors.forename: Maritza
authors.initials: M
authors.lastname: Román
authors.forename: Mario
authors.initials: M
authors.lastname: Chiong
authors.forename: Sergio
authors.initials: S
authors.lastname: Lavandero
mesh_terms: D000328:Adult; D000803:Angiotensin I / Q000097:blood*; D000804:Angiotensin II / Q000097:blood; D000959:Antihypertensive Agents / Q000097:blood*; D005260:Female; D017353:Gene Deletion; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000097:blood*; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D014662:Vasoconstrictor Agents / Q000097:blood
chemical_list: D000959:Antihypertensive Agents; D010446:Peptide Fragments; D014662:Vasoconstrictor Agents; D000804:Angiotensin II; D000803:Angiotensin I; D007703:Peptidyl-Dipeptidase A; C118790:angiotensin I (1-7)