Darkened Xenopus tadpoles appeared with neurochemical agents.
Skin darkened tadpoles sometimes appear spontaneously. Darkened was artificially induced in Xenopus larvae by yohimbine or chlorpromazine. These phenomena look like that are seen at pinealectomized or hypothalamus separated Xenopus larva. In this experiment, such a morphological color changed Xenopus larva is suggested by cause of inhibition of alpha2-adrenargic receptor or dopamine receptor from gastrula stages.
Sato
Eiji
E
Department of Biochemistry, Hamamatsu University, School of Medicine, Hamamatsu-shi, Handa-chou 1-20-1, 431-3192, Japan. satoeij1@hama-med.ac.jp
Shibata
Kiyoshi
K
Wu
Yi-Xin
YX
Uezato
Tadayoshi
T
Kobayashi
Katsumi
K
Miura
Naoyuki
N
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D010858:Pigmentation; D011954:Receptors, Dopamine / Q000502:physiology; D014981:Xenopus / Q000196:embryology*; D015016:Yohimbine / Q000494:pharmacology*
D000317:Adrenergic alpha-Antagonists; D018492:Dopamine Antagonists; D011954:Receptors, Dopamine; D015016:Yohimbine; D002746:Chlorpromazine