[Extended spectrum beta-lactamse (ESBL)-induced antibiotics resistance in gram-negative agents: what should be watched in intensive care medicine?].
Third-generation cephalosporins have an important part in the therapy of infections due to gram-negative bacteria. Extended spectrum beta-lactamases (ESBL) are able to hydrolize these antibiotics. As the number of ESBL-producing bacteria is increasing worldwide, detection of ESBL-producers is important for the both of prevention and therapy.
Kola
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A
Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover, Hannover, Germany. kola.axel@mh-hannover.de
Gastmeier
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P
D003422:Critical Care; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000201:enzymology; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases
Extended spectrum beta-Laktamase (ESBL)-vermittelte Antibiotikaresistenz bei gramnegativen Erregern: Was ist in der Intensivmedizin zu beachten?