title: Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial.
abstract: BACKGROUND
  Functional status and quality of life are important outcomes in the evaluation of revascularization approaches for symptomatic coronary artery disease. Few data are available regarding the comparative improvement in disease-specific health status after CABG versus percutaneous coronary intervention (PCI) in the era of coronary stenting.
  
  
  RESULTS
  Cardiac-specific health status was evaluated at baseline and at 6 and 12 months after intervention with the Seattle Angina Questionnaire (SAQ) in patients randomized to stent-assisted PCI (n=488) versus CABG (n=500) in the Stent or Surgery trial. Scores for physical limitation, angina frequency, and quality of life improved significantly for both treatment groups at 6 months (range of improvement from 13.6 to 34.7 points) and 12 months (14.3 to 38.2 points; all P<0.001). CABG patients had greater improvement than those assigned to PCI, although the magnitude of the difference decreased over time (difference at 6 months, 4.03 to 6.48 points; 12 months, 2.05 to 2.93 points). A component of this reduction is accounted for by PCI-arm patients who required repeat intervention. Differences between treatment groups were greatest for the 6-month angina frequency scores (difference=6.48 points; 95% CI 3.96 to 8.99). Overall, treatment satisfaction was high and did not differ significantly between groups.
  
  
  CONCLUSIONS
  Both CABG and stent-assisted PCI dramatically improved cardiac-related health status in patients with multivessel disease at 6- and 12-month follow-up. During the first postprocedure year, patients' angina burden and physical limitations were alleviated to a greater extent with CABG.
authors.affiliation: Division of Cardiology, Emory University School of Medicine, Atlanta, Ga 30306, USA.
authors.forename: Zefeng
authors.initials: Z
authors.lastname: Zhang
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Mahoney
authors.forename: Rodney H
authors.initials: RH
authors.lastname: Stables
authors.forename: Jean
authors.initials: J
authors.lastname: Booth
authors.forename: Fiona
authors.initials: F
authors.lastname: Nugara
authors.forename: John A
authors.initials: JA
authors.lastname: Spertus
authors.forename: William S
authors.initials: WS
authors.lastname: Weintraub
mesh_terms: D000787:Angina Pectoris / Q000453:epidemiology; D015906:Angioplasty, Balloon, Coronary; D003131:Combined Modality Therapy; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000601:surgery* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D015607:Stents; D016896:Treatment Outcome