Clinical features of uveal metastases in Korean patients.
OBJECTIVE
To report clinical features of uveal metastatic tumors in Korean patients who have different cancer profiles than those of patients in Western countries.


METHODS
The authors performed a retrospective chart review on all patients with evaluated uveal metastases.


RESULTS
Fourteen patients were diagnosed. One eye involved the iris, and 14 eyes of 13 patients involved the choroid. The metastases came from a primary cancer of the breast in four (29%), the lung in four (29%), the stomach in two (14%), the esophagus in one (7%), the common bile duct in one (7%), the kidney in one (7%), and unknown in one (7%). Thirteen (93%) of 14 choroidal metastases were associated with subretinal fluid, and eight (57%) eyes had tumors that were posterior to the equator. At the time of diagnosis, all patients had a history of cancer, and 11 patients had a metastatic lesion elsewhere. Three patients were undergoing chemotherapy. All three cases from gastric or esophageal cancer had a thicker choroidal mass and massive exudative retinal detachment.


CONCLUSIONS
The authors' series of uveal metastases showed a higher incidence from gastrointestinal cancer in Korean patients. Choroidal tumors from gastric or esophageal cancer seemed to be larger with massive exudation.
Lee
Jooyong
J
Department of Ophthalmology, Asan Medical Center, University of Ulsan, College of Medicine, 388-1 Poongnap-dong, Songpa-gu, Seoul 138-736, Korea.
Lee
Songeun
S
Sohn
Joonhong
J
Yoon
Young Hee
YH
D000328:Adult; D000368:Aged; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014604:Uveal Neoplasms / Q000175:diagnosis* / Q000208:ethnology / Q000556:secondary*