title: Importance of esophagogastroduodenoscopy in the evaluation of non-gastrointestinal mucosa-associated lymphoid tissue lymphoma.
abstract: OBJECTIVE
  Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma that most commonly presents in the gastrointestinal (GI) tract. However, it can present in non-GI primary sites. This study was conducted to determine the incidence of gastric involvement in non-GI presentation of MALT lymphoma.
  
  
  METHODS
  We retrospectively reviewed the medical records of 36 consecutive patients who presented with non-GI MALT lymphoma and had EGD as a part of the initial staging work-up between 1992 and 2001.
  
  
  RESULTS
  The median age was 62 years (range, 27-82); 27 were female patients. The frequency of the primary site was; salivary gland/parotid gland (N = 14), ocular adnexa (N = 7), lung (N = 3), oral cavity (N = 3), skin (N = 3), thyroid (N = 2), nasopharynx (N = 2), larynx (N = 1), breast (N = 1). Twelve patients were found to have gastric involvement; 2 additional patients progressed in the stomach 5 and 6 months later, respectively.
  
  
  CONCLUSIONS
  Routine evaluation of the stomach should be a part of the initial staging work-up of non-GI MALT lymphoma.
authors.affiliation: Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
authors.forename: Bouthaina S
authors.initials: BS
authors.lastname: Dabaja
authors.forename: Chul S
authors.initials: CS
authors.lastname: Ha
authors.forename: Richard B
authors.initials: RB
authors.lastname: Wilder
authors.forename: Barbara
authors.initials: B
authors.lastname: Pro
authors.forename: Peter
authors.initials: P
authors.lastname: McLaughlin
authors.forename: Fernando
authors.initials: F
authors.lastname: Cabanillas
authors.forename: James D
authors.initials: JD
authors.lastname: Cox
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016145:Endoscopy, Digestive System / Q000379:methods; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies