[Surgical treatment of giant cell tumor of bone].
BACKGROUND
This study analyses a 5-year follow-up after treatment of giant cell tumour of bone during a 31-year period.


METHODS
Sixty patients with giant cell tumours of bone had been treated at the Centre for Musculoskeletal Tumours at Aarhus University Hospital. All patients were followed at regular intervals for 5-35 years, median = 11 years.


RESULTS
There were 54 benign giant cell tumours of bone, whereas six were classified as malignant. The most common location was around the knee. There were nine cases of recurrence. The 5-year recurrence-free survival was 77%. The lowest frequency of recurrence appeared after resection (6%) and the highest after bone-transplantation (22%).


CONCLUSIONS
The classical microscopic and macroscopic criteria for malignancy are not applicable for this rare tumour. All giant cell tumours of bone should be considered as potentially malignant, and therefore patients should be referred to a Centre for Musculoskeletal Tumours.
Davidsen
Michael
M
Arhus Universitetshospital, Arhus Kommunehospital, Ortopaedkirurgisk Afdeling E, Onkologisk Afdeling D og Radiologisk afdeling R.
Keller
Johnny Ø
JØ
Jørgensen
Peter Holmberg
PH
Jurik
Anne Grethe
AG
Nielsen
Ole Steen
OS
Jensen
Olaf Myhre
OM
D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007717:Knee / Q000000981:diagnostic imaging; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011859:Radiography
Kirurgisk behandling af kaempecelletumorer i knogler.