title: Volumetric intravascular ultrasound evidence that distal embolization during acute infarct intervention contributes to inadequate myocardial perfusion grade.
abstract: We studied 35 consecutive patients with myocardial infarction (MI) who were treated with direct infarct percutaneous coronary intervention (PCI) using standard angiographic (complete assessment of flow grade and blush grade) and pre- and post-PCI volumetric intravascular ultrasound analysis. Plaque reduction, which is evidence of distal embolization, contributes to inadequate tissue reperfusion in this lesion setting and supports the use of distal protection in the setting of an acute MI.
authors.affiliation: Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA.
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kotani
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Jerzy
authors.initials: J
authors.lastname: Pregowski
authors.forename: Lukasz
authors.initials: L
authors.lastname: Kalinczuk
authors.forename: Augusto D
authors.initials: AD
authors.lastname: Pichard
authors.forename: Lowell F
authors.initials: LF
authors.lastname: Satler
authors.forename: William O
authors.initials: WO
authors.lastname: Suddath
authors.forename: Ron
authors.initials: R
authors.lastname: Waksman
authors.forename: Neil J
authors.initials: NJ
authors.lastname: Weissman
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D004617:Embolism / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D018084:Ultrasonography, Interventional