title: Clear cell myoepithelial carcinoma of the breast: a case report.
abstract: Primary clear cell myoepithelial carcinoma (CCMC) is extremely rare. During the past twenty years, only one CCMC case has been reported. Here, a case of CCMC is reported. A 30-year-old woman became aware of an abnormal mass on the left breast, and quadrantectomy was performed. Microscopically, it consisted of tumor cells that had clear cytoplasm and showed an invasive growth pattern. Immunohistochemically, the tumor was positive for alpha-smooth muscle actin, S-100, partly positive for vimentin and epithelial membranous antigen. From these findings, the tumor was diagnosed as CCMC. Most of the clear cell myoepithelial tumors are probably misclassified in other examples. It is expected that the numbers of CCMC may be increased by routinely performing special stains and immunohistochemical stains, even without ultrastructual study.
authors.affiliation: The First Department of Pathology, School of Medicine, Iwate Medical University, Morioka 020-8505, Japan. ysmiura@iwate-med.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Miura
authors.forename: Akira
authors.initials: A
authors.lastname: Kurose
authors.forename: Makoto
authors.initials: M
authors.lastname: Kondo
authors.forename: Akira
authors.initials: A
authors.lastname: Maruyama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Shibata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kanno
authors.forename: Takashi
authors.initials: T
authors.lastname: Sawai
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015412:Mastectomy, Segmental; D018396:Mucin-1 / Q000032:analysis; D009208:Myoepithelioma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin