Michael reaction of chitosan with various acryl reagents in water.
A Michael reaction of chitosan was conducted in water containing acetic acid with various acryl reagents. The degree of substitution could be controlled by temperature, reaction time, and the amount of acryl reagents. Although the modified chitosan derivatives with acrylic acid esters showed water-solubility, that with poly(ethylene glycol) acrylate, however, turned to water-insoluble material by lyophilization. Good biodegradation was observed in modified chitosan derivatives by standard activated sludge.
Sashiwa
Hitoshi
H
Green Biotechnology RG, The Special Division for Human Life Technology, AIST Kansai, 1-8-31 Midorigaoka, Ikeda 563-8577 Japan. h-sashiwa@aist.go.jp
Yamamori
Naoki
N
Ichinose
Yoshifumi
Y
Sunamoto
Junzo
J
Aiba
Sei-ichi
S
D000215:Acylation; D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D001673:Biodegradation, Environmental; D002686:Chitin / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D048271:Chitosan; D008279:Magnetic Resonance Imaging; D012722:Sewage; D012995:Solubility; D014867:Water
D001672:Biocompatible Materials; D012722:Sewage; D014867:Water; D002686:Chitin; D048271:Chitosan