title: [Antipsychotic agents: from phenothiazines to atypical neuroleptics of the second generation].
abstract: The paper addresses evolution of the problem of creation, characterization of the pharmacological properties, and elucidation of the mechanisms of action of antipsychotic drugs (neuroleptics)--one of the most important classes of modern psychotropic drugs. The appearance of these drugs marked the onset of a new era in psychiatry, the era of psychopharmacology. Special attention is devoted to the investigations in this direction at the Institute of Pharmacology, which were headed by V. V. Zakusov.
authors.affiliation: Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Baltiiskaya ul. 8, Moscow, 125315 Russia.
authors.forename: K S
authors.initials: KS
authors.lastname: Raevskiĭ
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D010640:Phenothiazines / Q000009:adverse effects / Q000627:therapeutic use*; D017982:Receptors, Biogenic Amine / Q000187:drug effects
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines; D017982:Receptors, Biogenic Amine
vernacular_title: Antipsikhoticheskie sredstva: ot fenotiazinov k atipichnym neĭroleptikam novogo pokoleniia.