Autoimmune hepatitis.
Autoimmune hepatitis is the archetype of liver autoimmune disease. It is divided into two types, according to the autoantibody profile. It should be suspected and diagnosed early since treatment is highly effective in preventing liver failure and transplant. The possible pathogenic scenario is described in the present review.
Vergani
Diego
D
Institute of Liver Studies, King's College Hospital, Denmark Hill, SE5 9RS London, UK. diego.vergani@kcl.ac.uk
Mieli-Vergani
Giorgina
G
D000818:Animals; D001323:Autoantibodies; D001402:B-Lymphocytes / Q000276:immunology; D020022:Genetic Predisposition to Disease; D019693:Hepatitis, Autoimmune; D006801:Humans; D008213:Lymphocyte Activation; D018716:Molecular Mimicry / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D001323:Autoantibodies