title: Relapsing polychondritis.
abstract: A 43-year-old Chilean man presented with a 5-month history of progressive hypertrophy of the ears bilaterally. He was seen initially by a dermatologist in Chile for complaints of erythema and swelling of the ears, and had been treated unsuccessfully with topical steroids and antimicrobial ointments. On presentation to our clinic, the hypertrophy had stabilized and the erythema had resolved, but he complained of decreased hearing due to narrowing of the external auditory canal. Associated symptoms included occasional pruritus, but he denied any pain. He also denied a history of sinus problems, respiratory symptoms, ocular pain, chest pain, and arthralgias. Physical examination revealed firm hypertrophy of the collagenous areas of both ears, sparing the ear lobes (Fig. 1). No pain was elicited on palpation. No conjunctivitis was noted and the nasal passages were clear. His chest was clear to auscultation. Histologic examination revealed a minimal perivascular infiltrate of lymphocytes and plasma cells in the dermis with fibrosis of the subcutis (Fig. 2). Blood tests showed a normal complete blood count, antinuclear antibody, and rheumatoid factor. Anti-collagen II antibodies were elevated at 29.2 Eu/ml (normal, 0-20 Eu/ml; borderline, 20-25 Eu/ml; elevated, > 25 Eu/ml).
authors.affiliation: Department of Dermatology, University of Utah, School of Medicine, Salt Lake City, Utah 84132, USA.
authors.forename: Clive M
authors.initials: CM
authors.lastname: Liu
authors.forename: Tissa R
authors.initials: TR
authors.lastname: Hata
authors.forename: Leonard
authors.initials: L
authors.lastname: Swinyer
authors.forename: Marta J
authors.initials: MJ
authors.lastname: Petersen
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004427:Ear Diseases / Q000175:diagnosis* / Q000473:pathology; D004431:Ear, External; D006801:Humans; D008297:Male; D011081:Polychondritis, Relapsing / Q000175:diagnosis* / Q000473:pathology