title: Radiation optic neuropathy after external beam radiation therapy for acromegaly: report of two cases.
abstract: For diagnosing radiation optic neuropathy (RON) ophthalmological and imaging data were evaluated from 63 acromegalic patients, irradiated between 1967 and 1998. Two patients developed RON: one patient in one optic nerve 10 years and another patient in both optic nerves 5 months after radiation therapy. RON is a rare complication after external beam radiation therapy for acromegaly, which can occur after a considerable latency period.
authors.affiliation: Department of Radiation Oncology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
authors.forename: Alfons C M
authors.initials: AC
authors.lastname: van den Bergh
authors.forename: Marjanke A
authors.initials: MA
authors.lastname: Hoving
authors.forename: Thera P
authors.initials: TP
authors.lastname: Links
authors.forename: Robin P F
authors.initials: RP
authors.lastname: Dullaart
authors.forename: Adelita V
authors.initials: AV
authors.lastname: Ranchor
authors.forename: Cees A
authors.initials: CA
authors.lastname: ter Weeme
authors.forename: Alof A
authors.initials: AA
authors.lastname: Canrinus
authors.forename: Ben G
authors.initials: BG
authors.lastname: Szabó
authors.forename: Jan Willem R
authors.initials: JW
authors.lastname: Pott
mesh_terms: D000172:Acromegaly / Q000532:radiotherapy*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000209:etiology*; D011832:Radiation Injuries; D011878:Radiotherapy / Q000009:adverse effects*