Clofarabine-induced acral erythema during the treatment of patients with myelodysplasia and acute leukemia: report of two cases.
Acral erythema has been associated with a number of chemotherapeutic agents, but there are no reports of clofarabine-induced acral erythema in the literature. We describe two patients who developed acral erythema after receiving clofarabine. One patient had myelodysplastic syndrome while the other had acute lymphoblastic leukemia.
Chiao
Nor
N
MD Anderson Cancer Center, 1515 Holcombe Boulevard--434, Houston, TX 77030-4009, USA.
Bumgardner
Amy
A
Duvic
Madeleine
M
D000227:Adenine Nucleotides; D000293:Adolescent; D001087:Arabinonucleosides / Q000009:adverse effects* / Q000627:therapeutic use; D000077866:Clofarabine; D004305:Dose-Response Relationship, Drug; D004890:Erythema / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D005533:Foot Dermatoses / Q000139:chemically induced / Q000473:pathology; D006229:Hand Dermatoses / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy
D000227:Adenine Nucleotides; D001087:Arabinonucleosides; D000077866:Clofarabine