title: [Irrigants and intracanal medicaments in endodontics].
abstract: Modern, biologic root canal therapy should be performed with suitable irrigating solutions and intracanal medicaments. The goal of endodontic treatment is to free the treated tooth from infection and prevent reinfection as thoroughly as possible by means which do not put the organism at risk. In this review of the literature, an evidence-based concept for irrigation and medication of root canal systems is presented. Irrigants and medicaments are discussed with respect to their antimicrobial, tissue-dissolving and endotoxin-decontaminating capacity in relation to their systemic toxicity. Recent findings pertaining to interactions of root canal medicaments and irrigating solutions and their impact on a sound irrigating and medicating concept are discussed.
authors.affiliation: Station für Endodontie, Klinik PPK, Zahnmedizinisches, Zentrum der Universität Zürich, Plattenstrasse 11, 8028 Zürich. matthias.zehnder@zzmk.unizh.ch
authors.forename: Matthias
authors.initials: M
authors.lastname: Zehnder
authors.forename: Birgit
authors.initials: B
authors.lastname: Lehnert
authors.forename: Kathrin
authors.initials: K
authors.lastname: Schönenberger
authors.forename: Tuomas
authors.initials: T
authors.lastname: Waltimo
mesh_terms: D000891:Anti-Infective Agents, Local / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D001421:Bacteria, Anaerobic / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D003737:Dental Cavity Preparation; D003786:Dental Pulp Cavity / Q000382:microbiology; D003790:Dental Pulp Necrosis / Q000188:drug therapy; D003804:Dentin / Q000382:microbiology; D004347:Drug Interactions; D004731:Endotoxins / Q000037:antagonists & inhibitors; D006801:Humans; D011671:Pulpitis / Q000188:drug therapy; D012387:Root Canal Filling Materials / Q000494:pharmacology; D012388:Root Canal Irrigants / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000891:Anti-Infective Agents, Local; D004731:Endotoxins; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants
vernacular_title: Spüllösungen und medikamentöse Einlagen in der Endodontie.