title: Experimental and numerical analysis of short-pulse laser interaction with tissue phantoms containing inhomogeneities.
abstract: The objective is to perform an experimental and numerical study to analyze short-pulse laser propagation through tissue phantoms without and with inhomogeneities embedded in them. For a short-pulse laser the observed optical signal has a distinct temporal shape, and the shape is a function of the medium properties. The scattered temporal transmitted and reflected optical signals are measured experimentally with a streak camera for tissue phantoms irradiated with a short-pulse laser source. A parametric study involving different scattering and absorption coefficients of tissue phantoms and inhomogeneities, as well as the detector positions and orientations, is performed. The temporal and spatial profiles of the scattered optical signals are compared with the numerical modeling results obtained by solving the transient radiative transport equation by using the discrete ordinates technique.
authors.affiliation: Department of Mechanical and Aerospace Engineering, Florida Institute of Technology, 150 West University Boulevard, Melbourne, Florida 32901, USA.
authors.forename: Champak
authors.initials: C
authors.lastname: Das
authors.forename: Ashish
authors.initials: A
authors.lastname: Trivedi
authors.forename: Kunal
authors.initials: K
authors.lastname: Mitra
authors.forename: Tuan
authors.initials: T
authors.lastname: Vo-Dinh
mesh_terms: D000042:Absorption; D007834:Lasers; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D010781:Photography; D012542:Scattering, Radiation