A randomized comparison of three insemination methods in an artificial insemination program using husbands' semen.
OBJECTIVE
To compare pregnancy rates with single intrauterine insemination (SIUI), double intrauterine insemination (DIUI) and fallopian tube sperm perfusion (FSP).


METHODS
Ninety patients undergoing a standard ovarian stimulation regimen were randomized to receive SIUI, DIUI or FSP. The end point was either pregnancy or completion of 3 treatment cycles without pregnancy.


RESULTS
There were no differences in demographic data or ovarian responses. The total number of motile spermatozoa inseminated in the FSP group was significantly lower than in the SIUI group. No significant differences were found in pregnancy rate per cycle or patient, multiple pregnancy rate and outcome of pregnancy between the 3 groups.


CONCLUSIONS
Similar pregnancy rates were achieved after SIUI, DIUI and FSP during stimulated cycles.
Ng
Ernest Hung Yu
EH
Department of Obstetrics and Gynaecology, University of Hong Kong, 6/F, Professorial Block, Queen Mary Hospital, Pokfulam Road, Hong Kong Special Administrative Region, People's Republic of China. nghye@hkucc.hku.hk
Makkar
Guneet
G
Yeung
William Shu Biu
WS
Ho
Pak Chung
PC
D000328:Adult; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007248:Infertility, Male / Q000628:therapy*; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D008297:Male; D010477:Perfusion; D011247:Pregnancy; D011256:Pregnancy Outcome; D013076:Sperm Count; D013081:Sperm Motility; D013997:Time Factors; D016896:Treatment Outcome