Managing a mouse mutant resource center...this is not your father's transgenic core.
Genetically engineered mice are making an increasingly valuable contribution to biomedical research, and many institutions have begun to assemble dedicated facilities for the development of transgenic animals. The authors describe the structure, function, and management of the transgenic core at NHGRI.
Garrett-Beal
Lisa J
LJ
Embryonic Stem Cell and Transgenic Core Facility, National Human Genome Research Institute/NIH, Room 4A52, Building 49, 49 Convent Drive, Bethesda, MD 20892-4472, USA. lgarrett@nhgri.nih.gov
Hoogstraten
Shelley L
SL
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D007756:Laboratory Animal Science / Q000458:organization & administration*; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D009316:National Institutes of Health (U.S.); D012040:Regional Health Planning; D014481:United States; D014730:Veterinary Medicine / Q000379:methods*