Combination therapy of tetracycline and tacrolimus resulting in rapid resolution of steroid-induced periocular rosacea.
Standard treatment of steroid-induced rosacea includes discontinuation of steroids and use of an oral tetracycline. A temporary decrease to a lower-potency steroid prior to discontinuation remains optional. The limitations of standard therapy include a prolonged course of treatment with exacerbations prior to permanent improvement. Our challenge was to identify a treatment regimen to resolve steroid-induced periocular rosacea quickly and with minimal rebound effect.
Pabby
Anju
A
Department of Dermatology and Skin Surgery, Roger Williams Medical Center, Providence, Rhode Island, USA.
An
Kathy P
KP
Laws
Richard A
RA
D000284:Administration, Oral; D000287:Administration, Topical; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011500:Protein Synthesis Inhibitors / Q000627:therapeutic use*; D012393:Rosacea / Q000139:chemically induced* / Q000188:drug therapy*; D013256:Steroids / Q000009:adverse effects*; D016559:Tacrolimus / Q000627:therapeutic use*; D013752:Tetracycline / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D011500:Protein Synthesis Inhibitors; D013256:Steroids; D013752:Tetracycline; D016559:Tacrolimus