Combined surgical and antifungal treatment of a subcutaneous infection due to Paecilomyces lilacinus.
Paecilomyces lilacinus was the causal agent of a case of subcutaneous infection in a patient with liver cirrhosis. Surgical treatment in combination with systemic amphotericin B therapy led to complete recovery. Retrospectively performed microdilution testing revealed dose dependent in vitro susceptibility of the isolate to voriconazole (MIC = 2 g/ml) and terbinafine (MIC = 1 microg/ml).
Kurzai
O
O
Institute of Hygiene and Microbiology, Department of Internal Medicine, University of Würzburg, Germany. okurzai@hygiene.uni-wuerzburg.de
Vaeth
T
T
Hamelmann
W
W
Müller
F M C
FM
Klinker
H
H
Langmann
P
P
Frosch
M
M
Mühlschlegel
F
F
D000038:Abscess / Q000150:complications / Q000188:drug therapy / Q000209:etiology / Q000601:surgery; D000328:Adult; D000666:Amphotericin B / Q000494:pharmacology / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003881:Dermatomycoses / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D005858:Germany; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008826:Microbial Sensitivity Tests; D010143:Paecilomyces / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity
D000935:Antifungal Agents; D000666:Amphotericin B