[Chemical constituents in the roots of Salvia przewalskii Maxim].
OBJECTIVE
To investigate the chemical composition of the root of Salvia przewalskii Maxim.


METHODS
Compounds were isolated by silica gel column chromatography. Structures of these compounds were elucidated by spectral analysis (EI-MS, FAB-MS, 1HNMR, 13CNMR, 1H-1H COSY, 1H-13C COSY, HMBC, NOESY) and phytochemical properties.


RESULTS
Eight compounds were isolated and identified as: tanshinone II-A (I), crypotanshinone (II), przewaquinone A (III), sugiol (IV), ursolic acid (V), 2 alpha, 3 alpha-dihydroxy urs-12-ene-28-acid (VI), oleanolic acid (VII), and neo-przewaquinone A (VIII).


CONCLUSIONS
Compound VIII is a new compound, and compound II, IV, V, VI and VII are isolated from this plant for the first time.
Chen
Wan-sheng
WS
College of Pharmacy, Second Military Medical University, Shanghai 200433, China. chenwansheng@21cn.com
Jia
Xin-ming
XM
Zhang
Wei-dong
WD
Lou
Zi-yang
ZY
Qiao
Chuan-zhuo
CZ
D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011809:Quinones / Q000737:chemistry / Q000302:isolation & purification*; D027544:Salvia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D000097245:Ursolic Acid
D006576:Heterocyclic Compounds, 4 or More Rings; D009828:Oleanolic Acid; D011809:Quinones; D014315:Triterpenes; D000097245:Ursolic Acid; C484875:neoprzewaquinone A