[Hyperthyrotropinemia in Mexican newborns].
OBJECTIVE
To assess the differences in the blood concentration levels of the thyroid stimulating hormone and their possible use as an indicator of iodine sufficiency, in a sample of Mexican newborns.


METHODS
A cross-sectional study was conducted from September 1999 to August 2000, among 25,427 Mexican newborns in the Ministry of Health clinics from 5 states. A total of 8,095 heel-prick and 17,332 umbilical cord blood samples were analyzed. Blood samples were collected in filter paper and processed by enzyme-linked immunosorbent assay. The Mann-Whitney U test and the Kruskal-Wallis test were used for statistical analyses.


RESULTS
Hyperthyrotropinemia was found in 9.95% of heel samples and in 24.27% of umbilical cord samples (TSH > 5 microUl/ml).


CONCLUSIONS
The percentage of hyperthyrotropinemia observed in this study was higher than that expected in a population with sufficient iodine intake; these findings could be due to poor maternal iodine intake.
Vela-Amieva
Marcela
M
Instituto Nacional de Pediatría, México, DF, México. amieva@servidor.unam.mx
Hernández-Osorio
Crescencio
C
Gamboa-Cardiel
Salvador
S
González-Contreras
Claudia R
CR
Pérez-Andrade
Martha Elva
ME
Ortiz-Cortés
Joel
J
Aguirre-Vélez
Blanca E
BE
D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood* / Q000175:diagnosis / Q000517:prevention & control; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D015997:Neonatal Screening; D013972:Thyrotropin / Q000097:blood / Q000172:deficiency*
D013972:Thyrotropin
Hipertirotropinemia en recién nacidos mexicanos.