Frequency modulated sweep responses in the medial geniculate nucleus.
A basic feature of communication signals is a dynamic change in frequency. One stimulus that lends itself well to investigating the frequency changes contained in these signals is the frequency modulated (FM) sweep. While many studies have investigated FM sweep responses in the auditory midbrain and cortex, relatively few have examined them in the thalamus. To this end, we investigated the responses of single units in the ventral division of the medial geniculate nucleus (MGNv) of the rat to FM sweeps. Both upward- (changing from low to high frequency) and downward-directed (changing from high to low frequency) FM sweeps were presented at four rates of frequency modulation (i.e., speed). Results showed that the majority (76%) of the cells preferred fast or medium FM sweeps. For direction selectivity, just under half of the units (47%) exhibited a preference for the direction of FM sweep. The results suggest that there is a greater degree of direction but not speed selectivity at progressively higher levels in the auditory pathway.
Lui
B
B
Department of Speech-Language Pathology, Faculty of Medicine, University of Toronto, Rehabilitation Sciences Building, 500 University Ave, Toronto, Ontario, M5G 1V7, Canada.
Mendelson
J R
JR
D000161:Acoustic Stimulation / Q000379:methods; D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001306:Auditory Pathways / Q000166:cytology / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D005829:Geniculate Bodies / Q000166:cytology / Q000502:physiology*; D008297:Male; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D010898:Pitch Perception / Q000502:physiology; D051381:Rats; D020318:Rats, Long-Evans; D011930:Reaction Time / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology