Radiation optic neuropathy after external beam radiation therapy for acromegaly: report of two cases.
For diagnosing radiation optic neuropathy (RON) ophthalmological and imaging data were evaluated from 63 acromegalic patients, irradiated between 1967 and 1998. Two patients developed RON: one patient in one optic nerve 10 years and another patient in both optic nerves 5 months after radiation therapy. RON is a rare complication after external beam radiation therapy for acromegaly, which can occur after a considerable latency period.
van den Bergh
Alfons C M
AC
Department of Radiation Oncology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Hoving
Marjanke A
MA
Links
Thera P
TP
Dullaart
Robin P F
RP
Ranchor
Adelita V
AV
ter Weeme
Cees A
CA
Canrinus
Alof A
AA
Szabó
Ben G
BG
Pott
Jan Willem R
JW
D000172:Acromegaly / Q000532:radiotherapy*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000209:etiology*; D011832:Radiation Injuries; D011878:Radiotherapy / Q000009:adverse effects*