Cytoskeletal regulation by Dictyostelium Ras subfamily proteins.
The Ras subfamily proteins are monomeric GTPases that function as molecular switches in cellular signal transduction. The roles of six of these proteins in regulating actin cytoskeletal functions in Dictyostelium discoideum are discussed in this review.
Lim
Chinten James
CJ
Department of Microbiology and Immunology, University of British Columbia, 300-6174 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z3.
Spiegelman
George B
GB
Weeks
Gerald
G
D000595:Amino Acid Sequence; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology; D003599:Cytoskeleton / Q000502:physiology*; D004023:Dictyostelium / Q000235:genetics / Q000502:physiology*; D017125:Genes, Protozoan; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment; D017384:Sequence Deletion; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D018631:ras Proteins / Q000235:genetics* / Q000378:metabolism*
D015800:Protozoan Proteins; D000242:Cyclic AMP; D018631:ras Proteins