[Magnetic resonance imaging for the diagnosis of multiple sclerosis].
Magnetic resonance imaging(MRI) is very useful as a method form confirming the lesion distribution of multiple sclerosis(MS). Although MS should be diagnosed primarily on clinical grounds, MRI aids the diagnosis by providing paraclinical evidence for the dissemination in both time and space. Recently, a new guideline for MS diagnosis was proposed by International Panel. This guideline set out to integrate MRI into the overall diagnostic scheme because of its unique sensitivity to pathological changes. In Japanese, however, the so-called optic-spinal form of MS, which is characterized by the selective involvement of the optic nerves and the spinal cord, is relatively common. Moreover, most of Japanese MS patients without oligoclonal bands show atypical brain lesions which do not fulfill the MRI criteria for brain abnormality.
Nakashima
Ichiro
I
Department of Neurology, Tohoku University School of Medicine.
Fujihara
Kazuo
K
Itoyama
Yasuto
Y
D044466:Asian People; D002490:Central Nervous System / Q000473:pathology; D006801:Humans; D007564:Japan; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology; D017410:Practice Guidelines as Topic; D012015:Reference Standards