title: Iron deficiency anaemia in Nigerian infants.
abstract: Hematological parameters and the iron status of 50 randomly selected infants who were attending the research infant welfare clinic of the Institute of Child Health, Ibadan (ICHI), for routine immunization were studied. Investigations included estimations of packed cell volume (PCV), haemoglobin (Hb), serum iron (Fe), unsaturated iron-binding capacity (UIBC) and total iron-binding Capacity (TIBC). Forty percent of the infants had PCVs below 0.32, 48% had Hbs below 10 g/dl and 27% had mean corpuscular volume (MVC) less that 70fl. Thirty-seven percent of the children had serum Fe below 3.58 mmol/l, but only 4% had UIBC above 320 mmol/l. Fifty-two percent had Transferin Saturation Index (TSI) below 10%. Eighteen percent had MCV below 70fl associated with TSI below 10% and 67% of these had Hbs below 10 g/dl. The prevalence of iron deficiency anaemia in infants as shown in this study is very high. The ill effects of iron deficiency in childhood have been well documented. It is suggested that screening for anaemia should be offered at 9 months as part of a Child Survival Programme and that infants found to be anaemic should be treated. However, for cost-effectiveness and taking into consideration the high prevalence rate of iron deficiency in this age group, it might be preferable to give iron and weekly prophylactic antimalarias routinely to infants aged 9 to 15 months in lieu of screening.
authors.affiliation: Institute of Child Health, College of Medicine, UCH, Ibadan, Nigeria.
authors.forename: F M
authors.initials: FM
authors.lastname: Akinkugbe
authors.forename: S I
authors.initials: SI
authors.lastname: Ette
authors.forename: T A
authors.initials: TA
authors.lastname: Durowoju
mesh_terms: D017677:Age Distribution; D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D001835:Body Weight; D003362:Cost-Benefit Analysis; D003906:Developing Countries; D004909:Erythrocyte Indices; D005247:Feeding Behavior; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007225:Infant Food; D007228:Infant Nutrition Disorders / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D007501:Iron / Q000097:blood; D008297:Male; D008403:Mass Screening / Q000191:economics / Q000379:methods; D020380:Needs Assessment; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D014168:Transferrin / Q000378:metabolism
chemical_list: D006454:Hemoglobins; D014168:Transferrin; D007501:Iron