title: Reliability of pressure-derived myocardial fractional flow reserve in assessing coronary artery stenosis in patients with previous myocardial infarction.
abstract: In 167 patients with suspected coronary artery disease, 74 of whom had myocardial infarction (MI), measurement of myocardial fractional flow reserve (FFR) in previous infarction territories, using a cut-off point of 0.75, showed a sensitivity of 79% and a specificity of 79% for myocardial ischemia as demonstrated by thallium-201 myocardial imaging. This sensitivity and specificity were similar to a sensitivity of 79% and a specificity of 72% observed in territories not related to MI. In addition, a receiver-operating characteristic curve analysis revealed that the best predictability of FFR for myocardial ischemia was between 0.74 and 0.76, regardless of the presence or absence of MI.
authors.affiliation: Department of Internal Medicine II, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Usui
authors.forename: Taishiro
authors.initials: T
authors.lastname: Chikamori
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Yanagisawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Morishima
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hida
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Takazawa
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D001810:Blood Volume; D023921:Coronary Stenosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology*; D017202:Myocardial Ischemia / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D015899:Tomography, Emission-Computed, Single-Photon