title: Sulfinimine-mediated asymmetric synthesis of beta-hydroxy alpha-amino phosphonates.
abstract: The addition of potassium dialkyl phosphites to enantiopure O-protected alpha-hydroxy sulfinimine pseudoenantiomers affords beta-hydroxy alpha-amino phosphonates in good yield and de. The reaction exhibits a strong match-mismatch effect.
authors.affiliation: Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA. fdavis@temple.edu
authors.forename: Franklin A
authors.initials: FA
authors.lastname: Davis
authors.forename: Kavirayani R
authors.initials: KR
authors.lastname: Prasad
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis*; D007097:Imines / Q000737:chemistry; D063065:Organophosphonates / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000737:chemistry
chemical_list: D000596:Amino Acids; D007097:Imines; D063065:Organophosphonates; D013452:Sulfonium Compounds