title: Determination of IgE in the serum of patients with allergic reactions to four species of fish-parasite anisakids.
abstract: This study investigates cross-reactions between somatic and metabolic antigens of various anisakids in the serum of patients with allergic processes. Twenty patients with allergic reactions after eating fish were studied using the skin-prick test for sensitivity to four species of anisakids. IgE was also determined, by blotting, in the serum of these patients when confronted with somatic and metabolic antigens of Anisakis simplex s.l. and Hysterothylacium aduncum, and somatic antigens of A. physeteris and H. fabri. The results obtained with both techniques basically agree, the following facts being of particular note: four patients presented specific IgE for A. simplex s.l. and 1 for Hysterothylacium sp. only, eight patients presented cosensitivity for A. simplex s.l. and A. physeteris, two for A. simplex s.l. and Hysterothylacium sp., one for A. physeteris and Hysterothylacium sp., and two for A. simplex s.l., A. physeteris and Hysterothylacium sp. Given the results obtained, it should be considered that other species of fish-parasite anisakids, apart from A. simplex s.l., may be involved in the allergic reactions presented by a large number of patients.
authors.affiliation: Departamento de Parasitología, Facultad de Farmacia, Universidad de Granada, Spain. avalero@ugr.es
authors.forename: A
authors.initials: A
authors.lastname: Valero
authors.forename: S
authors.initials: S
authors.lastname: Terrados
authors.forename: V
authors.initials: V
authors.lastname: Díaz
authors.forename: V
authors.initials: V
authors.lastname: Reguera
authors.forename: J
authors.initials: J
authors.lastname: Lozano
mesh_terms: D000818:Animals; D017163:Anisakis / Q000276:immunology*; D000947:Antigens, Helminth / Q000276:immunology*; D001199:Ascaridoidea / Q000276:immunology*; D003429:Cross Reactions; D005399:Fishes / Q000469:parasitology*; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000276:immunology*; D015151:Immunoblotting; D007073:Immunoglobulin E / Q000097:blood*; D012882:Skin Tests
chemical_list: D000947:Antigens, Helminth; D007073:Immunoglobulin E