title: Screening of volunteer students in Yaounde (Cameroon, Central Africa) for Chlamydia trachomatis infection and genotyping of isolated C. trachomatis strains.
abstract: The prevalence of Chlamydia trachomatis infection was 3.78% out of 1,277 volunteer students screened by direct fluorescence assay and Cobas Amplicor PCR. The infection was associated with the nonuse or inconsistent use of condoms in women (P = 0.026) and a previous sexually transmitted infection in men (P = 0.023). The most frequent genotypes determined by sequencing the omp1 genes of 25 clinical isolates were E (44%) and F (20%), and some strains harbored mutations, but E genotype strains did not.
authors.affiliation: Centre Pasteur du Cameroun, Yaounde, Cameroon. Laboratoire de Bactériologie, Centre National de Référence des Infections à Chlamydia, Université de Bordeaux II, Bordeaux, France.
authors.forename: Antoinette
authors.initials: A
authors.lastname: Ngandjio
authors.forename: Maithe
authors.initials: M
authors.lastname: Clerc
authors.forename: Marie Christine
authors.initials: MC
authors.lastname: Fonkoua
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Thonnon
authors.forename: Friede
authors.initials: F
authors.lastname: Njock
authors.forename: Regis
authors.initials: R
authors.lastname: Pouillot
authors.forename: Françoise
authors.initials: F
authors.lastname: Lunel
authors.forename: Christiane
authors.initials: C
authors.lastname: Bebear
authors.forename: Bertille
authors.initials: B
authors.lastname: De Barbeyrac
authors.forename: Anne
authors.initials: A
authors.lastname: Bianchi
mesh_terms: D000328:Adult; D002163:Cameroon / Q000453:epidemiology; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D002692:Chlamydia trachomatis / Q000145:classification* / Q000302:isolation & purification; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D018272:Porins / Q000737:chemistry / Q000235:genetics; D015995:Prevalence; D012307:Risk Factors
chemical_list: D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis