Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells.
Yamada
Masateru
M
Department of Molecular, Cell Pharmacology, National Research Institute for Child Health and Development, 3-35-31, Taishido, Setagaya, Tokyo 154-8567, Japan.
Hirasawa
Akira
A
Shiojima
Satoshi
S
Tsujimoto
Gozoh
G
D018931:Antineoplastic Agents, Hormonal / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D017209:Apoptosis; D003374:Coumarins / Q000494:pharmacology; D003907:Dexamethasone / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D020869:Gene Expression Profiling; D019254:Genes, bcl-2; D005938:Glucocorticoids / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D053804:Granzymes; D006801:Humans; D049934:Isocoumarins; D015448:Leukemia, B-Cell / Q000201:enzymology* / Q000235:genetics / Q000473:pathology; D008954:Models, Biological; D012333:RNA, Messenger / Q000096:biosynthesis; D012697:Serine Endopeptidases / Q000235:genetics / Q000502:physiology*; D015842:Serine Proteinase Inhibitors / Q000494:pharmacology; D014162:Transfection; D014407:Tumor Cells, Cultured
D018931:Antineoplastic Agents, Hormonal; D003374:Coumarins; D005938:Glucocorticoids; D049934:Isocoumarins; D012333:RNA, Messenger; D015842:Serine Proteinase Inhibitors; C046235:3,4-dichloroisocoumarin; D003907:Dexamethasone; D053804:Granzymes; D012697:Serine Endopeptidases; C509212:GZMA protein, human