Modulation of sensitivity and selectivity in plant signaling by proteasomal destabilization.
The ubiquitin (Ub) system of intracellular protein degradation regulates the abundance of numerous proteins that control plant growth and development. Recent advances have begun to illustrate how environmental and endogenous signals affect plant responses through Ub-related proteolysis, the importance of combinatorial control in regulated protein destruction and how multiprotein complexes confer sensitivity and selectivity to ubiquitination. Further insight into the cell biology of Ub-chain assembly and proteasomal degradation, as well as into the relationship between proteolysis and other regulatory modifications, will be essential for understanding the mechanistic basis of the integration of diverse plant signals.
Hare
Peter D
PD
The Laboratory of Plant Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, New York 10021-6399, USA.
Seo
Hak Soo
HS
Yang
Jun-Yi
JY
Chua
Nam-Hai
NH
D005298:Fertility / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D007113:Immunity, Innate / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D063245:Plant Development; D010937:Plant Growth Regulators / Q000494:pharmacology; D010944:Plants / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics* / Q000502:physiology; D025801:Ubiquitin / Q000235:genetics / Q000378:metabolism
D010937:Plant Growth Regulators; D025801:Ubiquitin