Absorbability of calcium from calcium-bound phosphoryl oligosaccharides in comparison with that from various calcium compounds in the rat ligated jejunum loop.
Calcium-bound phosphoryl oligosaccharides (POs-Ca) were prepared from potato starch. Their solubility and in situ absorbability as a calcium source were investigated by comparing with the soluble calcium compounds, calcium chloride and calcium lactate, or insoluble calcium compounds, calcium carbonate and dibasic calcium phosphate. The solubility of POs-Ca was as high as that of calcium chloride and about 3-fold higher than that of calcium lactate. An in situ experiment showed that the intestinal calcium absorption rate of POs-Ca was almost comparable with that of the soluble calcium compounds, and was significantly higher (p<0.05) than that of the insoluble calcium groups. Moreover, the total absorption rate of a 1:1 mixture of the calcium from POs-Ca and a whey mineral complex (WMC) was significantly higher (p<0.05) than that of WMC alone. These results suggest that POs-Ca would be a useful soluble calcium source with relatively high absorption in the intestinal tract.
To-o
Kenji
K
Biochemical Research Laboratory, Ezaki Glico Co., Ltd., Osaka 555-8502, Japan. too-kenji@glico.co.jp
Kamasaka
Hiroshi
H
Nishimura
Takahisa
T
Kuriki
Takashi
T
Saeki
Shigeru
S
Nakabou
Yukihiro
Y
D000818:Animals; D002118:Calcium / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics*; D002122:Calcium Chloride / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics; D017610:Calcium Compounds / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics; D007408:Intestinal Absorption; D007583:Jejunum / Q000378:metabolism* / Q000601:surgery; D007700:Kinetics; D007773:Lactates / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics; D008297:Male; D009844:Oligosaccharides / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics*; D010755:Organophosphates / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics; D051381:Rats; D017208:Rats, Wistar; D012995:Solubility; D013213:Starch / Q000737:chemistry; D013379:Substrate Specificity
D017610:Calcium Compounds; D007773:Lactates; D009844:Oligosaccharides; D010755:Organophosphates; C110051:calcium lactate; D013213:Starch; D002122:Calcium Chloride; D002118:Calcium