title: Comparison of maxillary implant-supported prosthesis in irradiated and non-irradiated patients.
abstract: In order to investigate the influence of radiation therapy after the treatment of maxillary implant-supported prostheses, 27 patients received a total of 131 implants in maxilla after oral cancer treatment and/or reconstructive surgery. Among them, 25 received maxillary implant-supported prostheses. The cumulative survival rates of implants and prostheses were evaluated by the product-limit-estimates method according to Kaplan-Meier. The cumulative survival rate of implants and prostheses in irradiated patients was compared with that in non-irradiated patients by statistical Log-rank test. The results showed that 112 implants were observed after implant loading. The implants cumulative survival rate was approximately 65% for overall patients. The cumulative prosthesis successful rate was approximately 88% for all 25 patients. Log-rank test analysis revealed that there was a significant difference in cumulative implants survival rates between non-irradiated and irradiated maxillary bone (P < 0.01). It was concluded that the implants and prostheses in irradiated patients have significantly lower survival rates than in non-irradiated patients.
authors.affiliation: Center of Stomatological Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
authors.forename: Yingguang
authors.initials: Y
authors.lastname: Cao
authors.forename: Thomas
authors.initials: T
authors.lastname: Weischer
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery*; D019094:Dental Prosthesis, Implant-Supported; D005260:Female; D006085:Graft Survival / Q000528:radiation effects*; D006801:Humans; D008297:Male; D008341:Mandibular Prosthesis; D008437:Maxilla / Q000601:surgery; D008447:Maxillofacial Prosthesis; D019931:Maxillofacial Prosthesis Implantation; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D016348:Osseointegration; D010865:Pilot Projects; D011832:Radiation Injuries; D012189:Retrospective Studies; D015996:Survival Rate; D014025:Titanium
chemical_list: D014025:Titanium