An unusual presentation of Castleman's disease:a case report.
BACKGROUND
Castleman's disease (CD), a rare condition of uncertain etiology, involves a massive proliferation of lymphoid tissues and typically presents as mediastinal masses. We describe a patient with CD who presented with diffuse adenopathy involving the inguinal, paratracheal, retroperitoneal, axillary, and pelvic regions.


METHODS
Case report describing presentation, work-up, management and clinical course of a patient with Castleman's disease in the setting of a county hospital in metropolitan area. Patient was treated with chemotherapeutic agents.


CONCLUSIONS
To our knowledge, this represents the first case of CD involving an HIV-positive patient with a negative Human Herpes Virus (HHV-8) viral panel. Because patients with similar clinical histories are at high risk for the development of non-Hodgkin's lymphoma and Kaposi sarcoma, regular medical surveillance is recommended.
Izuchukwu
Ifeoma S
IS
Department of Social and Preventive Medicine, State University of New York at Buffalo, 276 Farber Hall, Buffalo, NY, USA. dshaikhgroupe@aol.com
Tourbaf
Kamal
K
Mahoney
Martin C
MC
D000328:Adult; D001365:Axilla; D005871:Castleman Disease / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology* / Q000821:virology; D015658:HIV Infections / Q000150:complications; D006679:HIV Seropositivity; D019288:Herpesvirus 8, Human; D006801:Humans; D008297:Male