De novo SLE after cadaveric renal transplantation.
De novo lupus nephritis in a renal transplant recipient has not been previously reported. We present a transplant recipient with long-standing insulin-dependent diabetes mellitus who presented 9 years posttransplant with hematoproteinuria and acute renal failure. New findings of positive antinuclear antibody and double-stranded deoxyribonucleic antibody and renal histology findings consistent with lupus nephritis suggest a diagnosis of de novo systemic lupus erythematosis.
Laboi
Paul
P
Department of Renal Medicine and Histopathology, Leeds General Infirmary, Leeds, United Kingdom. paullaboi396@hotmail.com
Dedi
Robbie
R
Campbell
Helen
H
Hartley
Barrie
B
Turney
John H
JH
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001327:Autoimmune Diseases / Q000150:complications*; D002102:Cadaver; D002544:Cerebral Infarction / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003928:Diabetic Nephropathies / Q000601:surgery; D006801:Humans; D006973:Hypertension / Q000150:complications; D016030:Kidney Transplantation; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008181:Lupus Nephritis / Q000209:etiology; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications; D010291:Paresis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology*
D000974:Antibodies, Antinuclear