Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children.
Leucocyte Migration Inhibition Factor (L-MIF) was measured in 41 children with marasmus, 19 with kwashiorkor, 5 with marasmic-kwashiorkor and 35 well-fed healthy children serving as controls. For L-MIF assay, two different antigens (live attenuated measles virus vaccine and diptheria pertussis tetanus (DPT) vaccine were used. Percentage migration indices obtained with the two antigens were significantly higher in the malnourished than in the well-fed healthy sex and age-matched controls (P < 0.01). The total serum protein and albumin concentrations were significantly reduced in the malnourished children compared with the controls (P < 0.01). Mean total leucocyte numbers were not significantly different in marasmic and marasmic-kwashiorkor children compared with the controls (P > 0.21).
Fongwo
N P
NP
Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria.
Arinola
O G
OG
Salimonu
L S
LS
D001798:Blood Proteins / Q000378:metabolism; D016022:Case-Control Studies; D002648:Child; D015362:Child Nutrition Disorders / Q000097:blood* / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D007732:Kwashiorkor / Q000097:blood* / Q000276:immunology*; D007958:Leukocyte Count; D007961:Leukocyte Migration-Inhibitory Factors / Q000097:blood* / Q000276:immunology*; D008213:Lymphocyte Activation; D009549:Nigeria; D015596:Nutrition Assessment; D009752:Nutritional Status; D011502:Protein-Energy Malnutrition / Q000097:blood* / Q000276:immunology*; D012709:Serum Albumin / Q000032:analysis; D012720:Severity of Illness Index
D001798:Blood Proteins; D007961:Leukocyte Migration-Inhibitory Factors; D012709:Serum Albumin