[ Findings on optical coherence tomography in patients with macular degeneration treated with photodynamic therapy using Visudyne].
Findings on Optical Coherence Tomography in Macular Degeneration with Predominantly Classic Subfoveal Choroidal Neovascularization Treated by Photodynamic Therapy with Visudyne. We determined findings on optical coherence tomography (OCT) in macular degeneration with predominantly classic subfoveal choroidal neovascularization treated by photodynamic therapy (PDT) with Visudyne. We performed 21 correlations of central retinal thickness (CRT) on OCT2 with findings on fluorescein angiography (FA) in our study. We quantified CRT on OCT2 in 14 cases before, during and after the end of the treatment. The control group was composed from patients, who were not able to undergo the treatment and therefore it was postponed. CRT on OCT correlated with FA in 95% of cases in our study. Maximal decreasee of CRT is demonstrated during the first three months of treatment. Values of CRT on OCT are in patients after repeated sessions of PDT lower than before the first session. These values can grow up a little for some time due to increase of amount of intraretinal fluid during the first week after the session of PDT. During next follow-up there are no big differences between values of CRT. In the control group CRT on OCT increases progressively during the follow-up.
Cihelková
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Ocní klinika FNKV, Praha. cihelko@fnkv.cz
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D000077362:Verteporfin
D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin
Nálezy na optické koherentní tomografii u pacientů s makulární degenerací lécených pomocí fotodynamické terapie s preparátem Visudyne.