title: Peculiar pattern of nail pigmentation following cyclophosphamide therapy.
abstract: Cyclophosphamide is one of several cancer chemotherapy agents that can cause nail hyperpigmentation. We report a patient who began to have an unusual form of nail pigmentation after 8 months of receiving monthly pulses of dexamethasone-cyclophosphamide. The patient developed nail pigmentation that started proximally and spread distally but involved only the nails of the thumb, index finger, and half the middle finger of both hands.
authors.affiliation: Department of Dermatology and STD, JIPMER, Pondicherry, India.
authors.forename: Shriya
authors.initials: S
authors.lastname: Dave
authors.forename: Devinder M
authors.initials: DM
authors.lastname: Thappa
mesh_terms: D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009262:Nails / Q000187:drug effects*; D010392:Pemphigus / Q000188:drug therapy; D020551:Pulse Therapy, Drug
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003907:Dexamethasone; D003520:Cyclophosphamide