title: Novel radiator for carbon dioxide absorbents in low-flow anesthesia.
abstract: During long-term low-flow sevoflurane anesthesia, dew formation and the generation of compound A are increased in the anesthesia circuit because of elevated soda lime temperature. The object of this study was to develop a novel radiator for carbon dioxide absorbents used for long durations of low-flow sevoflurane anesthesia. Eleven female swine were divided into two groups comprising a "radiator" group (n = 5) that used a novel radiator for carbon dioxide absorbents and a "control" group (n = 6) that used a conventional canister. Anesthesia was maintained with N2O, O2, and sevoflurane, and low-flow anesthesia was performed with fresh gas flow at 0.6 L/min for 12 hr. In the "control" group, the soda lime temperature reached more than 40 degrees C and soda lime dried up with severe dew formation in the inspiratory valve. In the "radiator" group, the temperature of soda lime stayed at 30 degrees C, and the water content of soda lime was retained with no dew formation in the inspiratory valve. In addition, compound A concentration was reduced. In conclusion, radiation of soda lime reduced the amounts of condensation formed and the concentration of compound A in the anesthetic circuit, and allowed long term low-flow anesthesia without equipment malfunction.
authors.affiliation: Department of Anesthesiology, Tokyo Medical University, Tokyo, Japan. go-hira@kk.iij4u.or.jp
authors.forename: Go
authors.initials: G
authors.lastname: Hirabayashi
authors.forename: Takanori
authors.initials: T
authors.lastname: Mitsui
authors.forename: Takayasu
authors.initials: T
authors.lastname: Kakinuma
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Ogihara
authors.forename: Shohei
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Isshiki
authors.forename: Watanabe
authors.initials: W
authors.lastname: Yasuo
mesh_terms: D000042:Absorption; D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation*; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation; D000818:Animals; D001831:Body Temperature; D017610:Calcium Compounds; D002245:Carbon Dioxide / Q000032:analysis*; D002849:Chromatography, Gas; D004987:Ethers / Q000032:analysis / Q000378:metabolism; D005260:Female; D006845:Hydrocarbons, Fluorinated / Q000032:analysis / Q000378:metabolism; D008738:Methyl Ethers; D010087:Oxides; D000077149:Sevoflurane; D012972:Sodium Hydroxide; D013552:Swine; D013696:Temperature; D014867:Water
chemical_list: D018685:Anesthetics, Inhalation; D017610:Calcium Compounds; D004987:Ethers; D006845:Hydrocarbons, Fluorinated; D008738:Methyl Ethers; D010087:Oxides; D014867:Water; D002245:Carbon Dioxide; D000077149:Sevoflurane; C004569:soda lime; D012972:Sodium Hydroxide; C078742:fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether