Excessive fibrin after cataract surgery associated with aminocaproic acid use.
A 78-year-old woman developed a severe fibrinous anterior chamber reaction 1 day after uneventful clear corneal incision cataract extraction with intraocular lens implantation. There was no history of uveitis or diabetes, and the fibrin responded immediately to topical steroids. The patient was followed closely to rule out endophthalmitis. The only risk factor identified was the use of systemic aminocaproic acid as prophylaxis for bleeding in chronic leukemia.
Jabbur
Nada S
NS
The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. nsjabbur@jhmi.edu
D000368:Aged; D015119:Aminocaproic Acid / Q000009:adverse effects*; D000867:Anterior Chamber / Q000378:metabolism*; D000933:Antifibrinolytic Agents / Q000009:adverse effects*; D018916:Blood-Aqueous Barrier / Q000187:drug effects*; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D006801:Humans; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification
D000933:Antifibrinolytic Agents; D005337:Fibrin; D015119:Aminocaproic Acid