[A study on the incidence of cardiovascular disease on the metabolic syndrome in 11 provinces in China].
OBJECTIVE
To explore the association of metabolic syndrome with CVD in a cohort study involving 11 provinces.


METHODS
A cohort study was carried out in a population of 27 739 subjects (age 35 - 64 years). A baseline survey on the risk factor of cardiovascular disease was done in 1992. Incidence rate and relative risk were calculated for metabolic syndromes.


RESULTS
(1) The age-standardized incidence rate of cardiovascular disease for metabolic syndromes (MS) was higher than those without (MS) in this cohort (MS 652.3/100,000, not MS 206.7/100,000, RR = 3.12, P < 0.001). (2) The incidence rate of cardiovascular disease for patients with hypertension but low HDL cholesterol and high waist was the highest (910.2/100,000 in man, 930.7/100,000 in woman) among all metabolic syndromes patients. (3) The predictive risk factors for cardiovascular disease were age, cigarette smoking, BMI, total cholesterol and metabolic syndrome in men, with age, BMI and metabolic syndrome in women.


CONCLUSIONS
The incidence rate of cardiovascular disease on the metabolic syndrome was high in 11 provinces in China. Age, BMI and metabolic syndrome were the predictive risk factors of cardiovascular disease (especially of cerebrovascular disease). It is essential to prevent risk factors of cardiovascular disease in primary and secondary prevention programs in general population.
Wu
Gui-xian
GX
Department of Epidemiology, Beijing Heart, Lung and Blood Vessel Medical Center, Beijing 100029, China.
Wu
Zhao-su
ZS
Liu
Jing
J
Wang
Wei
W
Zhao
Dong
D
Hou
Lei
L
Zeng
Zhe-chun
ZC
Wang
Wen-hua
WH
Liu
Jun
J
Qin
Lan-ping
LP
Liu
Sa
S
D000328:Adult; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003327:Coronary Disease / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D016016:Proportional Hazards Models; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology