Parkinsonian features after streptococcal pharyngitis.
Bradykinesia and rigidity developed in a 10-year-old girl during an episode of Sydenham chorea. These parkinsonian features improved over 6 months. Serum analysis demonstrated elevated anti-streptolysin-O and anti-basal ganglia antibodies. We suggest that autoimmune antibodies may cause remitting parkinsonian signs subsequent to streptococcal tonsillitis as part of the spectrum of poststreptococcal CNS disease.
Ben-Pazi
Hilla
H
Pediatric Department, Hadassah University Hospital, Ein-Kerem, POB 12000, Jerusalem 91120, Israel. shmaryaho@hotmail.com
Livne
Amir
A
Shapira
Yehuda
Y
Dale
Russell C
RC
D000989:Antistreptolysin; D001323:Autoantibodies / Q000097:blood; D001485:Basement Membrane / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D020734:Parkinsonian Disorders / Q000209:etiology*; D010612:Pharyngitis / Q000150:complications* / Q000276:immunology; D013290:Streptococcal Infections / Q000150:complications* / Q000276:immunology
D001323:Autoantibodies; D000989:Antistreptolysin