title: Accumulation of Tc-99m depreotide (NeoSpect) in axillary sweat glands.
abstract: Tc-99m depreotide (NeoSpect) is a radiolabeled somatostatin analog introduced recently for scintigraphic imaging of patients with lung cancer. Eighteen patients were examined 2 to 4 hours after administration of 740 MBq mCi Tc-99m depreotide. In 13 patients (72.2%) bilateral symmetric activity corresponding to the large, deep apocrine sweat glands of the axillae was present. This observation is clinically relevant regardless of its reason or mechanism. It is important to be aware of this reason for activity in the axillae when assessing lymph node involvement not only in patients with lung cancer but also in breast cancer patients using scintigraphy with Tc-99m depreotide.
authors.affiliation: Division of Radiology, Center for Surgical Sciences, Karolinska Institutet, Stockholm, Sweden. Rimma.Danielsson@cfss.ki.se
authors.forename: Rimma
authors.initials: R
authors.lastname: Danielsson
authors.forename: Margaretha
authors.initials: M
authors.lastname: Bååth
authors.forename: Karl-Gustav
authors.initials: KG
authors.lastname: Kölbeck
authors.forename: Julius
authors.initials: J
authors.lastname: Klominek
authors.forename: Leif
authors.initials: L
authors.lastname: Svensson
mesh_terms: D001365:Axilla; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013004:Somatostatin / Q000031:analogs & derivatives*; D013545:Sweat Glands / Q000000981:diagnostic imaging*
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013004:Somatostatin; C444119:technetium Tc 99m depreotide