Recent advances in automated solid-phase carbohydrate synthesis: from screening to vaccines.
The past year has witnessed significant advances in a new technology for the synthesis of complex carbohydrates. Solid-phase methods have been applied to the construction of previously inaccessible carbohydrates. Furthermore, the application of automated solid-phase carbohydrate synthesis is promising. New methods for the synthesis of carbohydrates and potential applications are described in this review.
Plante
Obadiah J
OJ
Ancora Pharmaceuticals, 100 Cummings Center, Suite 419E, Beverly, MA 01915, USA. oplante@ancorapharma.com
Seeberger
Peter H
PH
D000818:Animals; D002241:Carbohydrates / Q000138:chemical synthesis* / Q000276:immunology / Q000302:isolation & purification; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008838:Microcomputers; D014612:Vaccines / Q000138:chemical synthesis*
D002241:Carbohydrates; D014612:Vaccines