title: Enantioselective chromenone benzoxazole receptor for glutamic acid and its derivatives.
abstract: Combination of a binaphthyl unit with chromenone benzoxazole fragments provided a chiral receptor that is enantioselective for glutamic acid and its derivatives. The receptor racemic mixture was resolved by TLCs impregnated with (R,R)-thiodilactic acid. High association constants were measured for dansylglutamic acid, using a fluorescent method. This receptor can be used for the resolution of the tosylglutamic acid racemic mixture.
authors.affiliation: Departamento de Química Orgánica, Plaza de los Caídos 1-5, Universidad de Salamanca, Salamanca, E-37008, Spain. romoran@usal.es
authors.forename: José V
authors.initials: JV
authors.lastname: Hernández
authors.forename: Ana I
authors.initials: AI
authors.lastname: Oliva
authors.forename: Luis
authors.initials: L
authors.lastname: Simón
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Muñiz
authors.forename: A Alonso
authors.initials: AA
authors.lastname: Mateos
authors.forename: Joaquín R
authors.initials: JR
authors.lastname: Morán
mesh_terms: D001583:Benzoxazoles / Q000737:chemistry*; D003619:Dansyl Compounds / Q000737:chemistry; D005971:Glutamates / Q000737:chemistry; D018698:Glutamic Acid / Q000031:analogs & derivatives*; D008958:Models, Molecular; D018716:Molecular Mimicry; D015394:Molecular Structure; D017470:Receptors, Glutamate / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001583:Benzoxazoles; D003619:Dansyl Compounds; D005971:Glutamates; D017470:Receptors, Glutamate; D018698:Glutamic Acid; C018257:dansylglutamic acid