title: Living-donor liver transplantation at Tokyo University.
abstract: One hundred fourteen living-donor liver transplants were performed at Tokyo University hospital from 1996-2000, including 66 children and 48 adults. Most (86%) of the children were transplanted for biliary atresia, whereas adults were more often transplanted for primary biliary cirrhosis (40%) or liver cirrhosis (23%) due to hepatitis or other unknown causes. Among children, 52% received the left lobe lateral segment, 23% an extended lateral segment and 21% the left lobe. The graft volume to standard liver ratio averaged 84%. Among adults, 79% received a left lobe; however, we have used the right lobe for most recent cases (21%) to provide sufficient volume. Parents donated to the pediatric recipients about 95% of the time, but a variety of family members donated for the adult transplants. The actual overall 3- and 5-year patient survival rates were 88.6% and 87.7%, respectively, and were slightly higher in children than adults. The results are comparable to those achieved with cadaver livers.
authors.affiliation: Liver Transplantation Team, Department of Surgery, University of Tokyo, Tokyo, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Hirata
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sugawara
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Makuuchi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008099:Liver / Q000033:anatomy & histology; D008107:Liver Diseases / Q000145:classification / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods / Q000706:statistics & numerical data*; D019520:Living Donors / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000145:classification / Q000453:epidemiology; D014041:Tokyo