title: Nutrition therapy for diabetic gastroparesis.
abstract: The management of diabetic gastroparesis often represents a significant clinical challenge in which the maintenance of nutrition is pivotal. Gastric emptying is delayed in 30% to 50% of patients with longstanding type 1 or type 2 diabetes and upper gastrointestinal symptoms also occur frequently. However, there is only a weak association between the presence of symptoms and delayed gastric emptying. Acute changes in blood glucose concentrations affect gastric motility in diabetes; hyperglycemia slows gastric emptying whereas hypoglycemia may accelerate it; blood glucose concentrations may also influence symptoms. It is now recognized that gastric emptying is a major determinant of postprandial glycemia and, therefore, there is considerable interest in the concept of modulating gastric emptying, by dietary or pharmacologic means, to optimize glycemic control in diabetes.
authors.affiliation: Department of Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia. michael.horowitz@adelaide.edu.au
authors.forename: Diana
authors.initials: D
authors.lastname: Gentilcore
authors.forename: Deirdre
authors.initials: D
authors.lastname: O'Donovan
authors.forename: Karen L
authors.initials: KL
authors.lastname: Jones
authors.forename: Michael
authors.initials: M
authors.lastname: Horowitz
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000150:complications; D001786:Blood Glucose; D048909:Diabetes Complications; D003929:Diabetic Neuropathies / Q000150:complications; D005746:Gastric Emptying / Q000502:physiology; D018589:Gastroparesis / Q000178:diet therapy* / Q000188:drug therapy / Q000209:etiology; D006801:Humans
chemical_list: D001786:Blood Glucose