title: alpha-Aminoacid derivatives of p-aminobenzoic acid with a potential antiarrhythmic activity.
abstract: Physico-chemical properties as well as two methods of synthesis of the title compounds have been described. The structures of new compounds (obtained as HCl or HBr salts) have been confirmed by elemental and spectral analysis (IR and 1H-NMR). The compounds should display a potential antiarrhythmic activity, as structural analogs of Procainamide.
authors.affiliation: Department of Pharmaceutical Chemistry, Institute of Drug Sciences, Faculty of Pharmacy, School of Medicine, 1 Banacha Str., 02-097 Warsaw, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Pirianowicz-Chaber
authors.forename: L
authors.initials: L
authors.lastname: Skulski
mesh_terms: D010129:4-Aminobenzoic Acid / Q000138:chemical synthesis / Q000494:pharmacology*; D000596:Amino Acids / Q000494:pharmacology*; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D002855:Chromatography, Thin Layer; D005750:Gastric Juice / Q000737:chemistry; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D007422:Intestines / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D062366:para-Aminobenzoates
chemical_list: D000596:Amino Acids; D000889:Anti-Arrhythmia Agents; D007202:Indicators and Reagents; D062366:para-Aminobenzoates; D010129:4-Aminobenzoic Acid