Experimental infection of recent field isolates of feline herpesvirus type 1.
Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical symptoms were observed on cats infected with the isolates 00-015 and 00-035 compared with those of C7301-infected cats. Severe ocular lesions including conjunctivitis were found in the cats infected with the isolates, indicating that the recent FHV-1 has a potential to induce severe FVR symptoms including ocular lesions.
Hamano
Masataka
M
Faculty of Agriculture, Yamaguchi University, Yoshida, Yamaguchi, Japan.
Maeda
Ken
K
Mizukoshi
Fuminori
F
Une
Yumi
Y
Mochizuki
Masami
M
Tohya
Yukinobu
Y
Akashi
Hiroomi
H
Kai
Kazushige
K
D000818:Animals; D001831:Body Temperature; D001835:Body Weight; D002371:Cat Diseases / Q000503:physiopathology / Q000821:virology*; D002415:Cats; D003231:Conjunctivitis / Q000662:veterinary / Q000821:virology; D006470:Hemorrhage / Q000662:veterinary / Q000821:virology; D006566:Herpesviridae Infections / Q000503:physiopathology / Q000662:veterinary*; D013997:Time Factors; D018140:Varicellovirus / Q000302:isolation & purification / Q000472:pathogenicity*