Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime-Hawaii, 2001.
We report 4 urogenital Neisseria gonorrhoeae isolates recovered from 3 patients that demonstrated resistance to penicillin, tetracycline, and ciprofloxacin and reduced susceptibility to cefixime. This report of the first 3 patients in the United States identified with this multidrug-resistant strain may portend an emerging problem for clinicians and public health officials.
Wang
Susan A
SA
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. Swang3@cdc.gov
Lee
Maria Veneranda C
MV
O'Connor
Norman
N
Iverson
Christopher J
CJ
Ohye
Roy G
RG
Whiticar
Peter M
PM
Hale
Judith A
JA
Trees
David L
DL
Knapp
Joan S
JS
Effler
Paul V
PV
Weinstock
Hillard S
HS
D000328:Adult; D000890:Anti-Infective Agents / Q000494:pharmacology*; D020682:Cefixime / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005260:Female; D024841:Fluoroquinolones; D006069:Gonorrhea / Q000382:microbiology; D006254:Hawaii / Q000453:epidemiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010403:Penicillin Resistance
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D020682:Cefixime