title: Clinical and angiographic results of coronary artery stenting using PURA-VARIO (PUVA) stents.
abstract: BACKGROUND
  Many different stent types are available for intracoronary placement. No clinical trial has demonstrated clearly the superiority of any stent design over another.
  
  
  METHODS
  This study was designed to analyze clinical and angiographic results after using intracoronary PURA-VARIO (Devon Medical, Hamburg, Germany) (PUVA) stents. A total of 306 implanted stents were investigated in a series of 217 unselected patients (61.2 +/- 10.7 years, 74.3% male). Stenting was performed electively and during acute coronary syndromes. Stents were manually mounted on angioplasty balloons and expanded in the target lesion. Angiographic measurements were carried out by quantitative coronary angiography.
  
  
  RESULTS
  Stenting was successful in 214/217 patients (98.8%). During hospitalization (median three days) 206 patients (94.9%) were free from adverse cardiac events. Stent thrombosis occurred in five patients (2.3%), Q-wave infarction in one (0.5%) and urgent percutaneous target vessel revascularization in four (1.8%). Follow-up angiography, performed in 170 patients (78.3%) showed a restenosis (>/=50% diameter stenosis) in 44/170 patients (25.9%), requiring angioplasty in 29 (17.2%). A surgical revascularization was recommended in 13 patients (7.6%). One patient died during follow-up from an unknown cause; however, sudden cardiac death was most likely.
  
  
  CONCLUSIONS
  PUVA stents are characterized by a high level of safety and efficacy. Clinical and angiographic results are comparable with those of other approved stents.
authors.affiliation: Department of Cardiology and Angiology, University Hospital Bergmannsheil, Bochum, Germany. alfried.germing@ruhr-uni-bochum.de
authors.forename: Alfried
authors.initials: A
authors.lastname: Germing
authors.forename: Michael
authors.initials: M
authors.lastname: Lindstaedt
authors.forename: Abderrahman
authors.initials: A
authors.lastname: Machraoui
authors.forename: Stefan
authors.initials: S
authors.lastname: von Dryander
authors.forename: Peter
authors.initials: P
authors.lastname: Grewe
authors.forename: Waldemar
authors.initials: W
authors.lastname: Bojara
authors.forename: Thomas
authors.initials: T
authors.lastname: Lawo
authors.forename: Bernd
authors.initials: B
authors.lastname: Lemke
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000628:therapy*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000628:therapy*; D017063:Outcome Assessment, Health Care; D011701:PUVA Therapy / Q000009:adverse effects*; D012720:Severity of Illness Index; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors