title: Prognosis for South Asian and white patients newly admitted to hospital with heart failure in the United Kingdom: historical cohort study.
abstract: OBJECTIVE
  To compare patterns of admission to hospital and prognosis in white and South Asian patients newly admitted with heart failure, and to evaluate the effect of personal characteristics and comorbidity on outcome.
  
  
  METHODS
  Historical cohort study.
  
  
  METHODS
  UK district health authority (population 960,000).
  
  
  METHODS
  5789 consecutive patients newly admitted with heart failure.
  
  
  METHODS
  Population admission rates, incidence rates for first admission with heart failure, survival, and readmission rates.
  
  
  RESULTS
  When compared with the white population, South Asian patients had significantly higher age adjusted admission rates (rate ratio 3.8 for men and 5.2 for women) and hospital incidence rates (2.2 and 2.9). Among 5789 incident cases of heart failure, South Asian patients were younger and more often male than white patients (70 (SD 0.6) v 78 (SD 0.1) years and 56.5% (190/336) v 49.3% (2494/5057)). South Asian patients were also more likely to have previous myocardial infarction (10.1% (n = 34) v 5.5% (n = 278)) or concomitant myocardial infarction (18.8% (n = 63) v 10.7% (n = 539)) or diabetes (45.8% (n = 154) v 16.2% (n = 817), all P < 0.001). A trend was shown to longer unadjusted survival for both sexes among South Asian patients. After adjustment for covariables, South Asian patients had a significantly lower risk of death (hazard ratio 0.82, 95% confidence interval 0.68 to 0.99) and a similar probability of death or readmission (0.96, 0.81 to 1.09) compared with white patients.
  
  
  CONCLUSIONS
  Population admission rates for heart failure are higher among South Asian patients than white patients in Leicestershire. At first admission South Asian patients were younger and more often had concomitant diabetes or acute ischaemic heart disease than white patients. Despite major differences in personal characteristics and risk factors between white and South Asian patients, outcome was similar, if not better, in South Asian patients.
authors.affiliation: Leicestershire Health Authority Department of Public Health Medicine.
authors.forename: Hanna M
authors.initials: HM
authors.lastname: Blackledge
authors.forename: James
authors.initials: J
authors.lastname: Newton
authors.forename: Iain B
authors.initials: IB
authors.lastname: Squire
mesh_terms: D001208:Asia / Q000208:ethnology; D002303:Cardiac Output, Low / Q000208:ethnology* / Q000628:therapy; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000208:ethnology; D016019:Survival Analysis; D006113:United Kingdom / Q000453:epidemiology