Thrombocytopenia in patients with chromosome 22q11.2 deletion syndrome.
Thrombocytopenia is a common finding in patients with chromosome 22q11.2 deletion syndrome. Patients with chromosome 22q11.2 deletion syndrome (n=112) were analyzed along with 57 age-matched controls. Even after the exclusion of patients with idiopathic thrombocytopenia purpura, the mean platelet count was approximately 70% of the control population.
Lawrence
Scott
S
Division of Allergy and Immunology, Division of Clinical Genetics, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA.
McDonald-McGinn
Donna M
DM
Zackai
Elaine
E
Sullivan
Kathleen E
KE
D002648:Child; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D004062:DiGeorge Syndrome / Q000235:genetics*; D006801:Humans; D012189:Retrospective Studies; D013577:Syndrome; D013921:Thrombocytopenia / Q000235:genetics*