title: Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core.
authors.affiliation: Institute of Cell Molecular Biology (ICMB), University of Edinburgh, Michael Swann Building, Mayfield Road, Edinburgh EH9 3RJ, Scotland, UK.
authors.forename: Dmitriy
authors.initials: D
authors.lastname: Alexeev
authors.forename: Paul N
authors.initials: PN
authors.lastname: Barlow
authors.forename: Stella M
authors.initials: SM
authors.lastname: Bury
authors.forename: Jean-Damien
authors.initials: JD
authors.lastname: Charrier
authors.forename: Alan
authors.initials: A
authors.lastname: Cooper
authors.forename: David
authors.initials: D
authors.lastname: Hadfield
authors.forename: Craig
authors.initials: C
authors.lastname: Jamieson
authors.forename: Sharon M
authors.initials: SM
authors.lastname: Kelly
authors.forename: Robert
authors.initials: R
authors.lastname: Layfield
authors.forename: R John
authors.initials: RJ
authors.lastname: Mayer
authors.forename: Helen
authors.initials: H
authors.lastname: McSparron
authors.forename: Nicholas C
authors.initials: NC
authors.lastname: Price
authors.forename: Robert
authors.initials: R
authors.lastname: Ramage
authors.forename: Lindsay
authors.initials: L
authors.lastname: Sawyer
authors.forename: Bernard A
authors.initials: BA
authors.lastname: Starkmann
authors.forename: Dusan
authors.initials: D
authors.lastname: Uhrin
authors.forename: Jill
authors.initials: J
authors.lastname: Wilken
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Young
mesh_terms: D007930:Leucine / Q000031:analogs & derivatives* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009154:Mutation; D011487:Protein Conformation; D011489:Protein Denaturation; D015202:Protein Engineering; D017510:Protein Folding; D012995:Solubility; D013237:Stereoisomerism; D014452:Ubiquitins / Q000138:chemical synthesis / Q000737:chemistry* / Q000235:genetics
chemical_list: D014452:Ubiquitins; D007930:Leucine