[Pharmacology of antiarrhythmia agents: the new aspects].
The paper describes new original drugs created at the Zakusov Institute of Pharmacology (Moscow). Cardiocyclide is a class III antiarrhythmic drug, producing a frequency-independent action; is a promising agent for the treatment of dangerous tachyarrhythmias. Bradizol is a class V antiarrhythmic drug producing a special bradycardiac action.
Kaverina
N V
NV
Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Baltiiskaya ul. 8, Moscow, 125315 Russia.
Chichkanov
G G
GG
D000085:Acetates / Q000494:pharmacology*; D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000503:physiopathology; D001562:Benzimidazoles / Q000494:pharmacology*; D002415:Cats; D003510:Cyclohexanes / Q000494:pharmacology*; D004285:Dogs; D004558:Electric Stimulation; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000503:physiopathology; D009206:Myocardium / Q000166:cytology; D018408:Patch-Clamp Techniques; D015221:Potassium Channels / Q000187:drug effects / Q000502:physiology; D011817:Rabbits; D011896:Rana temporaria; D051381:Rats; D013438:Sulfhydryl Compounds / Q000494:pharmacology*
C111159:2-(2-(diethylamino)ethyl)thio-5-ethoxybenzimidazole; D000085:Acetates; D000889:Anti-Arrhythmia Agents; D001562:Benzimidazoles; D003510:Cyclohexanes; C478369:N,N-dicyclohexylamide-N'-(3-diethylaminopropyl)-N-(N-nitrobenzoyl) aminoacetic acid hydroxyoxalate; D015221:Potassium Channels; D013438:Sulfhydryl Compounds
Farmakologiia antiaritmicheskikh sredstv: novye aspekty.