title: Piperidine glycosides targeting the ribosomal decoding site.
authors.affiliation: Department of Medicinal Chemistry, Anadys Pharmaceuticals Inc., 9050 Camino Santa Fe, San Diego, CA 92121, USA. ksimonsen@anadyspharma.com
authors.forename: Klaus B
authors.initials: KB
authors.lastname: Simonsen
authors.forename: Benjamin K
authors.initials: BK
authors.lastname: Ayida
authors.forename: Dionisios
authors.initials: D
authors.lastname: Vourloumis
authors.forename: Geoffrey C
authors.initials: GC
authors.lastname: Winters
authors.forename: Masayuki
authors.initials: M
authors.lastname: Takahashi
authors.forename: Sarah
authors.initials: S
authors.lastname: Shandrick
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhao
authors.forename: Thomas
authors.initials: T
authors.lastname: Hermann
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D001665:Binding Sites; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D008958:Models, Molecular; D015394:Molecular Structure; D010880:Piperidines / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D012329:RNA, Bacterial / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000378:metabolism*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D006027:Glycosides; D010880:Piperidines; D012329:RNA, Bacterial; D012335:RNA, Ribosomal