Late-onset diffuse lamellar keratitis.
BACKGROUND
Diffuse lamellar keratitis (DLK) is marked by the presence of diffuse or multifocal infiltrates confined to the laser in situ keratomileusis (LASIK) interface. These infiltrates are culture-negative, and the etiology is thought to be noninfectious. Most cases of DLK occur within the first week or 2 following surgery.


METHODS
We described 2 cases of DLK that occurred 3 months after LASIK. These patients were treated with intensive topical corticosteroids.


RESULTS
Treatment with topical corticosteroid was instituted, with rapid improvement in patient symptoms, visual acuity, and slit-lamp biomicroscopic findings.


CONCLUSIONS
DLK may occur as late as 3 months after LASIK.
Amano
Rie
R
Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
Ohno
Koji
K
Shimizu
Kimiya
K
Suzuki
Masanobu
M
Aizawa
Daisuke
D
Komatsu
Mari
M
D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D000305:Adrenal Cortex Hormones