Effects of the MEK inhibitor CI-1040 (PD 184352) on progenitor growth from normal and myelodysplastic marrow.
Steensma
David P
DP
Mesa
Ruben A
RA
Reeder
Terra L
TL
Tefferi
Ayalew
A
Kaufmann
Scott H
SH
D001549:Benzamides / Q000494:pharmacology*; D001853:Bone Marrow / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology / Q000502:physiology; D018922:HL-60 Cells; D006412:Hematopoietic Stem Cells / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology / Q000502:physiology; D006801:Humans; D020929:Mitogen-Activated Protein Kinase Kinases / Q000037:antagonists & inhibitors*; D009190:Myelodysplastic Syndromes / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D014407:Tumor Cells, Cultured
C120227:2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide; D001549:Benzamides; D020929:Mitogen-Activated Protein Kinase Kinases