The discovery of BMS-275183: an orally efficacious novel taxane.
D000284:Administration, Oral; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001682:Biological Availability; D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D006801:Humans; D020128:Inhibitory Concentration 50; D051379:Mice; D051381:Rats; D013329:Structure-Activity Relationship; D043823:Taxoids / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology
D000970:Antineoplastic Agents; C437188:BMS-275183; D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane