Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase.
D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D001572:Benzofurans / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects / Q000201:enzymology; D002177:Candidiasis / Q000188:drug therapy; D015195:Drug Design; D025141:Drug Resistance, Fungal / Q000235:genetics; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000493:pharmacokinetics / Q000494:pharmacology; D005656:Fungal Proteins / Q000037:antagonists & inhibitors; D020128:Inhibitory Concentration 50; D008297:Male; D011485:Protein Binding; D051381:Rats; D011916:Rats, Inbred F344; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D001572:Benzofurans; D004791:Enzyme Inhibitors; D005656:Fungal Proteins; D000217:Acyltransferases; C050480:glycylpeptide N-tetradecanoyltransferase