Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells.
D000036:Abrin / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000633:toxicity*; D017209:Apoptosis; D002460:Cell Line; D006801:Humans; D019169:Jurkat Cells; D007700:Kinetics; D008564:Membrane Potentials / Q000187:drug effects; D008928:Mitochondria / Q000187:drug effects* / Q000502:physiology; D011500:Protein Synthesis Inhibitors / Q000302:isolation & purification / Q000633:toxicity*; D000090063:Proto-Oncogene Mas; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D012270:Ribosomes / Q000187:drug effects; D015398:Signal Transduction
C000715470:MAS1 protein, human; D011500:Protein Synthesis Inhibitors; D000090063:Proto-Oncogene Mas; D019253:Proto-Oncogene Proteins c-bcl-2; D017382:Reactive Oxygen Species; D000036:Abrin