Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases.
D000818:Animals; D015152:Blotting, Northern; D002460:Cell Line; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000378:metabolism; D042783:Endothelial Cells / Q000378:metabolism; D000068876:Fingolimod Hydrochloride; D014644:Genetic Variation; D015894:Genome, Human; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007700:Kinetics; D051379:Mice; D008807:Mice, Inbred BALB C; D010766:Phosphorylation; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000737:chemistry / Q000378:metabolism*; D011409:Propylene Glycols / Q000493:pharmacokinetics*; D020033:Protein Isoforms; D017434:Protein Structure, Tertiary; D051381:Rats; D017208:Rats, Wistar; D013110:Sphingosine / Q000031:analogs & derivatives; D014018:Tissue Distribution; D000099157:Sphingosine Kinase
D018076:DNA, Complementary; D000068876:Fingolimod Hydrochloride; D007166:Immunosuppressive Agents; D017853:Phosphotransferases (Alcohol Group Acceptor); D011409:Propylene Glycols; D020033:Protein Isoforms; D013110:Sphingosine; D000099157:Sphingosine Kinase; C066324:ceramide kinase