Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays.
D000818:Animals; D001667:Binding, Competitive; D018360:Crystallography, X-Ray; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005454:Fluorescence Polarization; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry; D008024:Ligands; D051379:Mice; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry; D018160:Receptors, Cytoplasmic and Nuclear / Q000819:agonists / Q000737:chemistry*; D013329:Structure-Activity Relationship; D014157:Transcription Factors / Q000819:agonists / Q000737:chemistry*; D014443:Tyrosine / Q000031:analogs & derivatives / Q000737:chemistry
D005456:Fluorescent Dyes; D008024:Ligands; D010080:Oxazoles; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; C422415:farglitazar; D014443:Tyrosine