Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain.
D048868:Adaptor Proteins, Signal Transducing; D020816:Amino Acid Motifs; D000818:Animals; D001665:Binding Sites; D018360:Crystallography, X-Ray; D004305:Dose-Response Relationship, Drug; D056827:Endosomal Sorting Complexes Required for Transport; D004926:Escherichia coli / Q000378:metabolism; D051380:GRB2 Adaptor Protein; D018698:Glutamic Acid / Q000737:chemistry; D007700:Kinetics; D008024:Ligands; D051379:Mice; D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry; D010649:Phenylalanine / Q000737:chemistry; D010750:Phosphoproteins / Q000737:chemistry* / Q000378:metabolism; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D018909:src Homology Domains
D048868:Adaptor Proteins, Signal Transducing; D056827:Endosomal Sorting Complexes Required for Transport; D051380:GRB2 Adaptor Protein; C495949:Grb2 protein, mouse; D008024:Ligands; D010455:Peptides; D010750:Phosphoproteins; D011506:Proteins; C491648:Stam protein, mouse; C491646:Stam2 protein, mouse; D018698:Glutamic Acid; D010649:Phenylalanine