Akt1 protects against inflammatory microglial activation through maintenance of membrane asymmetry and modulation of cysteine protease activity.
D002462:Cell Membrane / Q000201:enzymology* / Q000473:pathology; D002470:Cell Survival / Q000502:physiology; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D019610:Cytoprotection / Q000502:physiology; D004789:Enzyme Activation / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000201:enzymology; D017628:Microglia / Q000201:enzymology* / Q000473:pathology*; D017346:Protein Serine-Threonine Kinases / Q000502:physiology*; D011518:Proto-Oncogene Proteins; D051057:Proto-Oncogene Proteins c-akt; D014407:Tumor Cells, Cultured
D011518:Proto-Oncogene Proteins; C494918:AKT1 protein, human; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D003546:Cysteine Endopeptidases