In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii.
D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism / Q000494:pharmacology; D003093:Colitis, Ulcerative / Q000188:drug therapy; D016503:Drug Delivery Systems; D005260:Female; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1 / Q000037:antagonists & inhibitors / Q000502:physiology; D007376:Interleukin-2 / Q000172:deficiency / Q000235:genetics; D007413:Intestinal Mucosa / Q000382:microbiology*; D008213:Lymphocyte Activation / Q000502:physiology; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009092:Mucous Membrane / Q000382:microbiology*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000096:biosynthesis / Q000627:therapeutic use; D012795:Sialoglycoproteins / Q000008:administration & dosage / Q000096:biosynthesis* / Q000627:therapeutic use; D013291:Streptococcus / Q000235:genetics / Q000378:metabolism*; D013950:Thymus Gland / Q000166:cytology; D014162:Transfection; D014621:Vagina / Q000382:microbiology
D001426:Bacterial Proteins; C507763:IL1RN protein, human; C507764:Il1rn protein, mouse; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D007376:Interleukin-2; D011994:Recombinant Proteins; D012795:Sialoglycoproteins