Neuroprotective effects of bilobalide, a component of Ginkgo biloba extract (EGb 761) in global brain ischemia and in excitotoxicity-induced neuronal death.
D000818:Animals; D000831:Animals, Newborn; D002545:Brain Ischemia / Q000150:complications*; D002452:Cell Count; D016923:Cell Death / Q000187:drug effects; D002470:Cell Survival; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000187:drug effects; D003517:Cyclopentanes / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004224:Diterpenes; D004305:Dose-Response Relationship, Drug; D003576:Electron Transport Complex IV / Q000235:genetics / Q000378:metabolism; D005663:Furans / Q000627:therapeutic use*; D005849:Gerbillinae; D020441:Ginkgo biloba; D046934:Ginkgolides; D018698:Glutamic Acid / Q000633:toxicity; D005998:Glycine / Q000633:toxicity; D006624:Hippocampus / Q000033:anatomy & histology / Q000378:metabolism; D017403:In Situ Hybridization / Q000379:methods; D066298:In Vitro Techniques; D020128:Inhibitory Concentration 50; D008297:Male; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry*; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D015424:Reperfusion / Q000379:methods; D029701:Saccharomyces cerevisiae Proteins; D020196:Trauma, Nervous System / Q000209:etiology / Q000517:prevention & control*; D000096983:Ginkgo Extract
D003517:Cyclopentanes; D004224:Diterpenes; D003576:Electron Transport Complex IV; D005663:Furans; D046934:Ginkgolides; D018698:Glutamic Acid; D005998:Glycine; D008565:Membrane Proteins; D010936:Plant Extracts; D012333:RNA, Messenger; D029701:Saccharomyces cerevisiae Proteins; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract; C093750:COX3 protein, S cerevisiae; C073710:bilobalide