Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells.
D000818:Animals; D002628:Chemoreceptor Cells / Q000378:metabolism; D016373:DNA, Antisense / Q000096:biosynthesis* / Q000235:genetics / Q000494:pharmacology*; D018076:DNA, Complementary / Q000096:biosynthesis*; D015536:Down-Regulation / Q000502:physiology; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology*; D005910:Glioma / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000517:prevention & control*; D006131:Growth Inhibitors / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000235:genetics / Q000502:physiology; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000235:genetics / Q000502:physiology; D014162:Transfection / Q000379:methods; D014407:Tumor Cells, Cultured
D016373:DNA, Antisense; D018076:DNA, Complementary; D006131:Growth Inhibitors; D019253:Proto-Oncogene Proteins c-bcl-2