Docosahexaenoic acid membrane content and mRNA expression of acyl-CoA oxidase and of peroxisome proliferator-activated receptor-delta are modulated in Y79 retinoblastoma cells differently by low and high doses of alpha-linolenic acid.
D042962:Acyl-CoA Oxidase; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D004281:Docosahexaenoic Acids / Q000032:analysis / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005786:Gene Expression Regulation / Q000187:drug effects / Q000502:physiology; D006801:Humans; D010088:Oxidoreductases / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D018160:Receptors, Cytoplasmic and Nuclear / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D012175:Retinoblastoma / Q000201:enzymology / Q000378:metabolism*; D014157:Transcription Factors / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D014407:Tumor Cells, Cultured; D017962:alpha-Linolenic Acid / Q000494:pharmacology*
D012333:RNA, Messenger; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D017962:alpha-Linolenic Acid; D004281:Docosahexaenoic Acids; D010088:Oxidoreductases; D042962:Acyl-CoA Oxidase