Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme.
D000328:Adult; D000525:Alprazolam / Q000493:pharmacokinetics; D018592:Cross-Over Studies; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003915:Dextromethorphan / Q000378:metabolism; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D006801:Humans; D020902:Hypericum; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D013379:Substrate Specificity
D010936:Plant Extracts; D003915:Dextromethorphan; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; D019389:Cytochrome P-450 CYP2D6; D051544:Cytochrome P-450 CYP3A; D000525:Alprazolam