The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609.
D000217:Acyltransferases / Q000378:metabolism; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D020126:Brefeldin A / Q000494:pharmacology; D001952:Bridged-Ring Compounds / Q000494:pharmacology*; D020169:Caspases / Q000378:metabolism; D002518:Ceramides / Q000378:metabolism*; D006224:Cricetinae; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000378:metabolism; D015852:Eukaryotic Initiation Factor-2 / Q000378:metabolism; D005260:Female; D037341:Fumonisins / Q000494:pharmacology; D051379:Mice; D009636:Norbornanes; D010766:Phosphorylation / Q000187:drug effects; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D051102:Serine C-Palmitoyltransferase; D013109:Sphingomyelins / Q000378:metabolism; D013859:Thiocarbamates; D013871:Thiones / Q000494:pharmacology*; D017855:Transferases (Other Substituted Phosphate Groups) / Q000378:metabolism
D001952:Bridged-Ring Compounds; D002518:Ceramides; D015852:Eukaryotic Initiation Factor-2; D037341:Fumonisins; D009636:Norbornanes; D013109:Sphingomyelins; D013859:Thiocarbamates; D013871:Thiones; D020126:Brefeldin A; C056933:fumonisin B1; C046498:tricyclodecane-9-yl-xanthogenate; D000217:Acyltransferases; D051102:Serine C-Palmitoyltransferase; D011065:Poly(ADP-ribose) Polymerases; D017855:Transferases (Other Substituted Phosphate Groups); C070186:phosphatidylcholine-ceramide phosphocholine transferase; D020169:Caspases