[Thyroid antagonists. X. Action of the methylene ether of 4-methyl-6-oxo-2-thio-5-pyrimidinol, of the methylene ether of 5-ethyl-4-methyl-2-thiouracil, of 5-ethyl-4-methyl-2-thiouracil, and of the methylene ether of 4,5-dimethyl-2-thiouracil on the weight curve, oxygen consumption and thyroid and pituitary histological pictures after parenteral administration to rats].
D000818:Animals; D013956:Antithyroid Agents; D001835:Body Weight / Q000187:drug effects*; D004986:Ether; D008660:Metabolism; D008697:Methane / Q000031:analogs & derivatives; D008779:Methylthiouracil; D010101:Oxygen Consumption; D004364:Pharmaceutical Preparations; D010900:Pituitary Diseases; D010902:Pituitary Gland / Q000187:drug effects*; D011725:Pyridines / Q000494:pharmacology*; D051381:Rats; D013889:Thiouracil / Q000031:analogs & derivatives; D013961:Thyroid Gland / Q000187:drug effects*
D013956:Antithyroid Agents; D004364:Pharmaceutical Preparations; D011725:Pyridines; D004986:Ether; C030011:carbene; D013889:Thiouracil; D008697:Methane; D008779:Methylthiouracil
BODY WEIGHT/effect of drugs on; METABOLISM; PITUITARY GLAND/effect of drugs on; PYRIDINES/effects; THIOURACIL/derivatives; THYROID GLAND/effect of drugs on
Contributo allo studio delle sostanze antitroidee. X. Azione dell'etere metilenico del 2-tio-4-metil-6-ossi-5-pirimidin-alcool, dell'etere metilenico del 4-metil-5-etil-2-tio-uracile, del 4-metil-5-etil-2-tio-uracile e dell'etere metilenico del 4-5-dimetil-2-tio-uracile somministrati per via parenterale sulla curva ponderale, sul consumo di O2,e quadro istologico tiroideo ed ipofisario del ratto.