Pathologic effects of antimetabolites. I. Acute lesions in the hypothalamus, peripheral ganglia, and adrenal medulla caused by 3-acetyl pyridine and prevented by nicotinamide.
D000313:Adrenal Medulla / Q000187:drug effects*; D000963:Antimetabolites; D005724:Ganglia; D007031:Hypothalamus / Q000473:pathology*; D009525:Niacin / Q000031:analogs & derivatives; D009536:Niacinamide; D009539:Nicotinic Acids; D010525:Peripheral Nerves / Q000473:pathology*; D011725:Pyridines / Q000633:toxicity*
D000963:Antimetabolites; D009539:Nicotinic Acids; D011725:Pyridines; C010835:3-acetylpyridine; D009536:Niacinamide; D009525:Niacin; C023666:pyridine
ADRENAL MEDULLA/effect of drugs on; HYPOTHALAMUS/pathology; NERVES, PERIPHERAL/pathology; NICOTINIC ACID/derivatives; PYRIDINES/toxicity