Macroglobulinemia. I. The antigenic relationship of pathological macroglobulins to normal gamma-globulins.
Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal gamma(1)-macroglobulin (19S) as well as the 7S gamma-globulins. The pathological macroglobulins differ among each other and they are antigenically deficient when compared with the normal macroglobulin. There is no correlation between the macroglobulin's antigenic structure and its physico-chemical properties.
D000941:Antigens; D007074:Immunoglobulin G; D008259:Macroglobulins; D012712:Serum Globulins; D008258:Waldenstrom Macroglobulinemia; D005719:gamma-Globulins
D000941:Antigens; D007074:Immunoglobulin G; D008259:Macroglobulins; D012712:Serum Globulins; D005719:gamma-Globulins
GAMMA GLOBULIN; SERUM GLOBULIN