Xanthomatous biliary cirrhosis following chlorpromazine, with observations indicating overproduction of cholesterol, hyperprothrombinemia, and the development of portal hypertension.
D002746:Chlorpromazine / Q000009:adverse effects*; D002784:Cholesterol / Q000097:blood*; D006801:Humans; D006973:Hypertension; D006975:Hypertension, Portal / Q000209:etiology*; D008064:Lipidoses / Q000209:etiology*; D008103:Liver Cirrhosis / Q000209:etiology*; D008105:Liver Cirrhosis, Biliary; D011516:Prothrombin; D019851:Thrombophilia
D011516:Prothrombin; D002784:Cholesterol; D002746:Chlorpromazine
CHLORPROMAZINE/injurious effects; CHOLESTEROL/in blood; HYPERTENSION, PORTAL/etiology and pathogenesis; LIPOIDOSIS/etiology and pathogenesis; LIVER CIRRHOSIS/etiology and pathogenesis; PROTHROMBIN