[Foundation of a chemotherapy for cancer based upon the primary inhibition of glucose phosphorylation (hexokinase reaction) by influencing the substrate, the coenzyme and the enzyme].
D000970:Antineoplastic Agents; D003067:Coenzymes; D005947:Glucose; D006593:Hexokinase; D006801:Humans; D009369:Neoplasms; D010766:Phosphorylation; D010770:Phosphotransferases
D000970:Antineoplastic Agents; D003067:Coenzymes; D010770:Phosphotransferases; D006593:Hexokinase; D005947:Glucose
CYTOTOXIC DRUGS; TRANSPHOSPHORYLASES
Science. 1956 Feb 24;123(3191):309-14
13298683
Science. 1956 Aug 17;124(3216):314-5
13351646
J Natl Cancer Inst. 1955 Oct;16(2):351-404
13263911
Science. 1957 Mar 15;125(3246):496-8
13408996
Biochim Biophys Acta. 1953 Sep-Oct;12(1-2):329-46
13115442
J Natl Cancer Inst. 1954 Oct;15(2):215-37
13233880
J Natl Cancer Inst. 1956 Nov;17(5):615-29
13377177
J Natl Cancer Inst. 1955 Oct;16(2):405-14
13263912
Uber die Begründung einer Chemotherapie des Krebses auf der Grundlage einer primären Hemmung der Glucosephosphorylierung (Hexokinase-Reaktion) durch Beeinflussung von Substrat, Coenzym und Enzym.