Tests for collateral sensitivity or cross resistance in bacterial mutants resistant to amethopterin or purine analogs.
D000963:Antimetabolites; D001412:Bacillus subtilis / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects*; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D008727:Methotrexate; D011687:Purines / Q000494:pharmacology*
D000963:Antimetabolites; D005493:Folic Acid Antagonists; D011687:Purines; C030985:purine; D008727:Methotrexate
BACILLUS SUBTILIS/effect of drugs on; ESCHERICHIA COLI/effect of drugs on; FOLIC ACID ANTAGONISTS/effects; PURINES/effects