Hypothyroidism and goiter due to defects in the intrathyroidal synthesis of thyroxine.
D006042:Goiter / Q000209:etiology*; D007037:Hypothyroidism / Q000209:etiology*; D013974:Thyroxine / Q000378:metabolism*
D013974:Thyroxine
GOITER/etiology and pathogenesis; HYPOTHYROIDISM/etiology and pathogenesis; THYROXIN/metabolism