title: [Anesthetic management of a patient with deficiency of congenital coagulation factor XII].
abstract: A 63-year-old man with deficiency of congenital coagulation factor XII, was referred to our hospital for an operation of the hypopharynx cancer. The day before surgery under general anesthesia, fresh frozen plasma was administered to him with good response of APTT shortening from 397.0 to 36.4 seconds. During operation, bleeding tendency was controlled and fresh frozen plasma was administered. Total blood loss during the operation was 255 ml. During post-operative period, APTT was kept at an adequate level. The post-operative course was uneventful and he was discharged after the radiation and an adjuvant therapy.
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D005175:Factor XII Deficiency / Q000151:congenital*; D006801:Humans; D007013:Hypopharynx; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D019990:Perioperative Care; D010610:Pharyngeal Neoplasms / Q000601:surgery; D010949:Plasma