title: Quality of life aspects in kidney cancer patients: data from a national registry.
abstract: OBJECTIVE
  We investigated quality of life aspects, including health-related quality of life, psychological functioning, relationship issues and sexual functioning in kidney cancer patients.
  
  
  METHODS
  We conducted an anonymous, cross-sectional survey of a random sample of patients with kidney cancer from a national database. A questionnaire was mailed to 301 members of the Kidney Cancer Association. The questionnaire included demographics, medical history, the Watts Sexual Function Questionnaire (WSFQ), the SF-12 Health Survey, the Center for Epidemiologic Studies Depression Scale (CES-D), and the Revised Dyadic Adjustment Scale (RDAS).
  
  
  RESULTS
  Of the 266 eligible participants, 84 (33%) returned the questionnaire. The mean ages of the respondents were 57.5 and 57.9 years for men and women, respectively. Overall, the total WSFQ scores as well as the four domain scores (desire, arousal, orgasm and satisfaction) were similar in men and women, and lower than in female breast cancer and male hypertensive populations reported in the literature, indicating relatively worse sexual function. While subjects reported health-related quality of life and relationship scores similar to the general population, 51% of men and 57% of women reported depressive symptoms (CES-D >/=16).
  
  
  CONCLUSIONS
  This is the first study in which sexual function in patients with renal cancer has been addressed. While most patients remain sexually active in non-distressed relationships, many reported depressive symptoms, and sexual functioning may be worse than in comparable chronically ill populations. Quality of life and sexual function issues should be addressed when counseling urological cancer patients.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000523:psychology; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D012042:Registries; D012307:Risk Factors; D012725:Sexual Behavior / Q000523:psychology*; D020018:Sexual Dysfunctions, Psychological / Q000209:etiology* / Q000523:psychology; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014481:United States