[Fetal anesthesia in cesarean section for patients with congenital diaphragmatic hernia].
We experienced two cases of anesthesia for cesarean section in patients with prenatally diagnosed congenital diaphragmatic hernia (CDH). Fentanyl/midazolam anesthesia was selected for fetal sedation at birth. The blood samples were obtained from the maternal vein, umbilical vein and umbilical artery for measuring blood drug concentrations during anesthesia. Midazolam concentrations in umbilical vein were 137 and 256 ng.ml-1. Spontaneous breathing and movement of the newborns were restrained in both cases and these sedations facilitated preoperative general management for newborns with CDH.
D000328:Adult; D000767:Anesthesia, Epidural; D000768:Anesthesia, General / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D005260:Female; D005333:Fetus; D006548:Hernia, Diaphragmatic / Q000175:diagnosis / Q000601:surgery*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011296:Prenatal Diagnosis