title: 2-aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity.
abstract: A series of 2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles was synthesized and tested for antiarrhythmic, local anaesthetic and analgesic activity. The title compounds showed a good antinociceptive activity.
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis / Q000494:pharmacology*; D000779:Anesthetics, Local / Q000138:chemical synthesis / Q000494:pharmacology; D000814:Aniline Compounds / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis / Q000494:pharmacology; D003460:Crystallization; D004339:Drug Compounding; D005260:Female; D007191:Indazoles / Q000138:chemical synthesis / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D010147:Pain Measurement; D051381:Rats; D013329:Structure-Activity Relationship; D044366:Transition Temperature; D014693:Ventricular Fibrillation / Q000188:drug therapy
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D000814:Aniline Compounds; D000889:Anti-Arrhythmia Agents; D007191:Indazoles