Isoflavonoids from roots of Erythrina zeyheri.
Five isoflavonoids, (+/-)-7,2',4'-trihydroxy-8,3'-di(gamma,gamma-dimethylallyl)isoflavanone, (3R)-7,4'-dihydroxy-2'-methoxy-6,8-di(gamma,gamma-dimethylallyl)isoflavanone, (3R)-7,2',4'-trihydroxy-6,8-di(gamma,gamma-dimethylallyl)isoflavan, 2',4'-dihydroxy-8-gamma,gamma-dimethylallyl-2",2"-dimethylpyrano-[5,6:6,7]isoflavan and (6aS, 11aS)-3,6a-dihydroxy-9-methoxy-4,10-di(gamma,gamma-dimethylallyl)pterocarpan, along with five known compounds, were isolated from the roots of Erythrina zeyheri. Their structures were established on the basis of spectroscopic evidence, and their antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA) were estimated by determining minimum inhibitory concentrations.
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004895:Erythrina / Q000737:chemistry*; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D018517:Plant Roots / Q000737:chemistry; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism
D000890:Anti-Infective Agents; D007529:Isoflavones