Caspofungin salvage therapy in a neutropenic patient with probable invasive aspergillosis: a case report.
A 47-year-old man with acute lymphocytic leukemia was admitted in intensive care unit (ICU) because of respiratory failure. He had febrile neutropenia and probable invasive pulmonary aspergillosis (IA). Amphotericin B renal toxicity and clinical deterioration prompted a shift to caspofungin and resulted in a successful response.
D000935:Antifungal Agents / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001228:Aspergillosis / Q000188:drug therapy / Q000276:immunology; D002051:Burkitt Lymphoma / Q000188:drug therapy; D000077336:Caspofungin; D054714:Echinocandins; D006801:Humans; D055666:Lipopeptides; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy; D010455:Peptides / Q000008:administration & dosage*; D010456:Peptides, Cyclic; D012074:Remission Induction; D016879:Salvage Therapy; D013997:Time Factors; D016896:Treatment Outcome
D000935:Antifungal Agents; D000970:Antineoplastic Agents; D054714:Echinocandins; D055666:Lipopeptides; D010455:Peptides; D010456:Peptides, Cyclic; D000077336:Caspofungin