Distribution of hepatitis B virus genotypes in HIV-infected patients with chronic hepatitis B: therapeutic implications.
Hepatitis B virus (HBV) genotypes were examined in HIV-infected patients with chronic HBV infection seen in our clinic during 2002. A total of 28 of 1100 individuals (prevalence 2.5%) were found to be HBsAg and HBV-DNA positive. HBV genotypes could be determined in 23 of them. HBV-A was the most common (57%), followed by HBV-D (39%). HBV-A predominated among homosexual men (67%) while HBV-D predominated among intravenous drug users (67%). The presence of serum HBeAg was significantly associated with the HBV-A genotype.
D000328:Adult; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D015497:HIV-1 / Q000302:isolation & purification*; D006513:Hepatitis B e Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000235:genetics*; D019694:Hepatitis B, Chronic / Q000150:complications / Q000453:epidemiology / Q000821:virology*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D015819:Substance Abuse, Intravenous
D006513:Hepatitis B e Antigens