title: [Spinal anesthesia in a parturient complicated with idiopathic thrombocytopenic purpura].
abstract: A 27-yr-old parturient with idiopathic thrombocytopenic purpura was scheduled to undergo resection of a left ovarian cyst at 15 weeks gestation. Platelet counts were between 46,000 and 64,000.microliter-1, bleeding time was 2 min, and she denied having unusual bleeding diathesis. As the patient was reluctant to receive general anesthesia for fear of latent adverse effects of the drugs on the fetus, we selected spinal anesthesia and the perioperative course was uneventful. However, it is questionable to perform regional anesthesia in patients with coagulation disorders, for spinal hematomas leading to paraplegia can be a rare but devastating complication of regional anesthesia. According to our extensive literature review, it was revealed that platelet insufficiency, both in terms of function and count, did not represent a major risk factor for spinal hematomas associated with regional anesthesia, especially for spinal anesthesia. We suggest that spinal anesthesia may be safely performed in patients if their platelet counts exceed around 50,000.microliter-1.
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000775:Anesthesia, Spinal / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006408:Hematoma, Subdural / Q000209:etiology; D006801:Humans; D010048:Ovarian Cysts / Q000150:complications* / Q000601:surgery*; D010976:Platelet Count; D011247:Pregnancy; D011248:Pregnancy Complications; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications*; D012307:Risk Factors