Facile aminoacylation of pdCpA dinucleotide with a nonnatural amino acid in cationic micelle.
A simple and versatile method for aminoacylation of a dinucleotide (pdCpA) in aqueous micellar solution was developed by using a hydrophobic amino acid derivative, N-pentenoyl-L-2-naphthylalanine cyanomethyl ester (Pen-napAla-OCM), and a CTACl micelle.
D000215:Acylation; D015153:Blotting, Western; D002412:Cations; D002851:Chromatography, High Pressure Liquid; D015226:Dinucleoside Phosphates / Q000737:chemistry*; D007202:Indicators and Reagents; D008823:Micelles; D012346:RNA, Transfer, Amino Acyl / Q000138:chemical synthesis*; D019809:Streptavidin / Q000737:chemistry; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000737:chemistry
D002412:Cations; D015226:Dinucleoside Phosphates; D007202:Indicators and Reagents; D008823:Micelles; D012346:RNA, Transfer, Amino Acyl; D015091:beta-Alanine; C062195:5'-phospho-2'-deoxyribocytidylylriboadenosine; C063914:beta-naphthylalanine; D019809:Streptavidin