In vitro anti-acanthamoeba action by thioureidic derivatives.
The anti-amoebic power of a series of bis-thioureidic derivatives against amoeba, responsible for a serious form of keratitis of the cornea, has been analysed. The synthesis of these products is also described.
D000048:Acanthamoeba / Q000187:drug effects*; D000563:Amebicides / Q000494:pharmacology*; D000818:Animals; D003315:Cornea / Q000469:parasitology; D006801:Humans; D066298:In Vitro Techniques; D007634:Keratitis / Q000469:parasitology; D009682:Magnetic Resonance Spectroscopy; D021261:Parasitic Sensitivity Tests; D013329:Structure-Activity Relationship; D013890:Thiourea / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000494:pharmacology
D000563:Amebicides; D013890:Thiourea