Methods for the assessment of quality and stability of azidocillin.
UV and VIS spectrophotometric methods, after previous chromatographic separation (TLC/UV) and iodometric methods were adapted for the determination of azidocillin in presence of its breakdown products. These methods were applied for kinetic measurement of changes in the azidocillin concentration with time in water solutions and solid state. Using thin layer chromatography several decomposition products of azidocillin were detected.
D004355:Drug Stability; D010400:Penicillin G / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000493:pharmacokinetics / Q000592:standards*; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000592:standards
D010400:Penicillin G; C100243:azidocillin