title: Bilateral exophthalmos in a Holstein cow with lymphosarcoma.
abstract: A 4-year-old Holstein cow presented with severe bilateral exophthalmos. A complete blood cell count revealed late stage lymphoma; the agar gel immunodiffusion test for enzootic bovine leukosis was positive. The cow was euthanized 1 wk after presentation. Necropsy revealed generalized lymphadenopathy and tumors in most organs. Final diagnosis was lymphosarcoma.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D016583:Enzootic Bovine Leukosis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D037901:Euthanasia, Animal; D005094:Exophthalmos / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D005260:Female