title: Laser immunotherapy: a novel treatment modality for metastatic tumors.
abstract: Laser immunotherapy is a novel approach for the treatment of metastatic tumors. It combines a selective photothermal laser-tissue interaction for direct tumor destruction and an immunoadjuvant-directed simulation for immune responses. In experiments using a rat metastatic tumor model, laser immunotherapy resulted in the eradication of both treated primary tumors and untreated metastases at remote sites. It also induced anti-tumor resistance.
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D002686:Chitin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D048271:Chitosan; D005260:Female; D007167:Immunotherapy / Q000379:methods*; D007208:Indocyanine Green / Q000494:pharmacology; D015552:Injections, Intralesional; D007279:Injections, Subcutaneous; D053685:Laser Therapy; D008325:Mammary Neoplasms, Experimental / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D009362:Neoplasm Metastasis / Q000628:therapy*; D009368:Neoplasm Transplantation; D051381:Rats; D016019:Survival Analysis; D015996:Survival Rate
chemical_list: C121252:glycated chitosan; D002686:Chitin; D048271:Chitosan; D007208:Indocyanine Green