Alteration of mutation frequency by treatment with actinomycin D.
The frequency of lethal mutations occurring in Drosophila melanogaster was reduced by approximately one-half when irradiated males were treated with actinomycin D, which also inhibited the appearance of melanotic atypical growths in the strain used for the study.
D000818:Animals; D003609:Dactinomycin / Q000494:pharmacology*; D004331:Drosophila melanogaster; D005823:Genetics / Q000528:radiation effects*; D008297:Male; D009154:Mutation; D059645:Mutation Rate; D011830:Radiation Effects
D003609:Dactinomycin
ACTINOMYCIN/pharmacology; GENETICS/radiation effects; RADIATION EFFECTS/experimental