Quantal and graded analysis of dosage-effect relations.
Loewe's recommendations regarding treatment of stimulus-response relations are criticized. Conditions are described where quantal analysis is justified. Loewe's interpretation of his graded analysis must be modified in the light of the fact that response curves for individuals frequently cross. Superior lines of attack on the problem are suggested.
D000818:Animals; D001522:Behavior, Animal; D006801:Humans; D010600:Pharmacology
PHARMACOLOGY