Physico-chemical and immunological observations on the abnormal proteins in three patients with cryoglobulinaemia.
Three new cases of cryoglobulinaemia are described, and in each case the presence of the cryoglobulin appeared to be unrelated to the clinical manifestations. Although when examined by paper electrophoresis the abnormal proteins behaved uniformly as normal gamma globulins, marked differences in nature were revealed when ultracentrifugal and immunological analyses were made. One patient had an abnormal protein which behaved both as a cryoglobulin and as a macroglobulin.
D002446:Celiac Disease / Q000097:blood*; D003449:Cryoglobulinemia; D004586:Electrophoresis; D006801:Humans; D008107:Liver Diseases / Q000097:blood*; D010488:Polyarteritis Nodosa / Q000097:blood*; D012712:Serum Globulins; D005719:gamma-Globulins
D012712:Serum Globulins; D005719:gamma-Globulins
ELECTROPHORESIS; LIVER DISEASES/blood; PERIARTERITIS NODOSA/blood; SERUM GLOBULIN; SPRUE/blood