Prothrombin time. Determination by a whole blood micro-method for control of anticoagulant therapy.
A micro technique that is here described for "prothrombin time" determinations, employing capillary whole blood, provides a range of values which is closely correlated with the Quick one-stage plasma method, thus providing inter-changeability of results both in normal persons and in patients who have been treated with anticoagulant drugs. Avoidance of the use of a water bath and centrifuge permit this technique to yield immediate results at the bedside, in the office or in the patient's home. The use of a whole blood instead of a plasma technique lends additional safety to control of anticoagulant medication, since it may reflect depression of clotting factors not apparent by the usual plasma methods.
D000925:Anticoagulants / Q000628:therapy*; D002196:Capillaries; D006801:Humans; D010949:Plasma; D011517:Prothrombin Time
D000925:Anticoagulants
ANTICOAGULANTS/therapy; PROTHROMBIN TIME