An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis.
Two consecutive trials of out-patient treatment for mild cases of active ulcerative colitis are described. In the first trial oral prednisone gave significantly better results than a placebo. In the second trial "salazopyrin" gave final results approaching those of prednisone, although over a longer time and with a higher incidence of unpleasant side-effects, but topical hydrocortisone gave disappointing results, probably because the technique of administration was not suitable for ordinary out-patient use.
D000553:Ambulatory Care; D003093:Colitis, Ulcerative / Q000628:therapy*; D006801:Humans; D006854:Hydrocortisone / Q000628:therapy* / Q000031:analogs & derivatives; D010045:Outpatients; D011241:Prednisone / Q000628:therapy*; D000077145:Sulfanilamide; D013424:Sulfanilamides; D012460:Sulfasalazine; D013449:Sulfonamides / Q000628:therapy*
D013424:Sulfanilamides; D013449:Sulfonamides; D000077145:Sulfanilamide; D012460:Sulfasalazine; C038363:hydrocortisone valerate; C007133:hydrocortisone hemisuccinate; D011241:Prednisone; D006854:Hydrocortisone
COLITIS, ULCERATIVE/therapy; HYDROCORTISONE/therapy; PREDNISONE/therapy; SULFONAMIDES/therapy