Theoretical design of continuous antibiotic fermentation units.
A graphic method of predicting antibiotic yields in continuous flow reactors is presented and discussed using the novobiocin fermentation as a model process. Extension to other antibiotic fermentations and steroid bioconversions is emphasized. In the case of the novobiocin fermentation it was concluded that a combination of one growth stage and one or two antibiotic production stages would be the most economic reactor system to conduct such a fermentation on a continuous basis.
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000904:Antibiotics, Antitubercular; D004345:Drug Industry / Q000600:supply & distribution*; D004864:Equipment and Supplies; D005285:Fermentation; D009675:Novobiocin
D000900:Anti-Bacterial Agents; D000904:Antibiotics, Antitubercular; D009675:Novobiocin
ANTIBIOTICS/chemistry; DRUG INDUSTRY/equipment and supplies