Excessive stimulation of salivary gland growth by isoproterenol.
In the rat, chronic treatment with isoproterenol can cause a selective growth of the salivary glands to approximately five times their normal size within 17 days. This enlargement is principally due to mitotic proliferation and hypertrophy of the parenchymatous cells.
D000818:Animals; D006984:Hypertrophy; D007545:Isoproterenol; D051381:Rats; D012466:Salivary Gland Diseases; D012469:Salivary Glands; D013566:Sympathomimetics / Q000633:toxicity*
D013566:Sympathomimetics; D007545:Isoproterenol
SALIVARY GLANDS/diseases; SYMPATHOMIMETICS/toxicology