The inhibition by morphine of the action of smooth muscle stimulants on the guinea-pig intestine.
Morphine and related analgesics depress the responses of the isolated guinea-pig ileum to nervous stimulation and to drugs which act by stimulating the nervous structures of the intestinal wall. The present experiments show that these analgesics also depress the responses to smooth muscle stimulants which act directly on the smooth muscle fibres.
D000700:Analgesics; D000697:Central Nervous System Stimulants; D006168:Guinea Pigs; D007082:Ileum; D007422:Intestines; D009020:Morphine / Q000494:pharmacology*; D009130:Muscle, Smooth; D009132:Muscles / Q000502:physiology*
D000700:Analgesics; D000697:Central Nervous System Stimulants; D009020:Morphine
MORPHINE/pharmacology; MUSCLES/physiology