The effect of corticotrophin zinc on plasma 17-hydroxycorticoids as a test of adrenal cortical function.
The response of plasma 17-hydroxycorticoids to corticotrophin has been determined using a simplified technique. Steroid levels appeared to be maximal four hours after the injection of 40 units of corticotrophin zinc. No response was obtained in cases of Addison's disease and a sluggish increase occurred in hypopituitarism. The effect of steroid therapy is discussed.
D000302:Adrenal Cortex / Q000502:physiology*; D000305:Adrenal Cortex Hormones / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D003366:Cosyntropin; D006801:Humans; D010949:Plasma; D015032:Zinc
D000305:Adrenal Cortex Hormones; D003366:Cosyntropin; C006418:adrenocorticotropin zinc; D000324:Adrenocorticotropic Hormone; D015032:Zinc
ADRENAL CORTEX HORMONES/blood; ADRENAL CORTEX/physiology; CORTICOTROPIN/pharmacology