Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.
D001669:Biochemical Phenomena; D004351:Drug Resistance; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D007938:Leukemia / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D013762:Tetrahydrofolate Dehydrogenase
D005493:Folic Acid Antagonists; D010088:Oxidoreductases; D013762:Tetrahydrofolate Dehydrogenase
DEHYDROGENASES/metabolism; FOLIC ACID ANTAGONISTS/pharmacology; LEUKEMIA/metabolism