The use of S-(2-aminoethyl)-isothiuronium bromide hydrobromide (AET) to localize the effect of alkylating agents and to extend their therapeutic index in the treatment of neoplastic ascites.
D000477:Alkylating Agents; D000970:Antineoplastic Agents / Q000628:therapy*; D001201:Ascites; D001965:Bromides; D007550:Isothiuronium; D009369:Neoplasms / Q000502:physiology*; D013890:Thiourea / Q000031:analogs & derivatives; D000338:beta-Aminoethyl Isothiourea
D000477:Alkylating Agents; D000970:Antineoplastic Agents; D001965:Bromides; D000338:beta-Aminoethyl Isothiourea; D007550:Isothiuronium; D013890:Thiourea
ANTINEOPLASTIC AGENTS/therapy; NEOPLASMS/physiology; THIOUREA/related compounds