Use of an osmotic diuretic-THAM-in treatment of barbiturate poisoning. Alkalinizing action of drug and its ability to increase elimination of electrolytes in urine appears to facilitate clearance of barbiturates.
D001463:Barbiturates / Q000633:toxicity*; D004232:Diuretics / Q000494:pharmacology*; D004234:Diuretics, Osmotic; D004573:Electrolytes; D006018:Glycols / Q000494:pharmacology*; D014325:Tromethamine
D001463:Barbiturates; D004232:Diuretics; D004234:Diuretics, Osmotic; D004573:Electrolytes; D006018:Glycols; D014325:Tromethamine; C032232:barbituric acid
BARBITURATES/toxicology; DIURETICS/pharmacology; GLYCOLS/pharmacology