Histamine metabolism.
Some recent discoveries about the formation, storage and catabolism of histamine are reviewed. Histamine is formed by decarboxylation of histidine and stored principally in the mast cells of connective tissue. Human lung and facial skin are particularly rich in histamine. When histamine is injected intravenously, simulating spontaneous release, it is rapidly metabolized and excreted.
D006632:Histamine / Q000378:metabolism*; D006801:Humans; D008168:Lung; D008407:Mast Cells; D012867:Skin
D006632:Histamine
HISTAMINE/metabolism