Chronic and sustained hypernatremia, absence of thirst, diabetes insipidus, and adrenocorticotrophin insufficiency resulting from widespread destruction of the hypothalamus.
D000309:Adrenal Insufficiency; D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D003919:Diabetes Insipidus; D006646:Histiocytosis, Langerhans-Cell; D006801:Humans; D006955:Hypernatremia; D007031:Hypothalamus; D008499:Medical Records; D012964:Sodium / Q000097:blood*; D013894:Thirst
D000324:Adrenocorticotropic Hormone; D012964:Sodium
CORTICOTROPIN/deficiency; HAND-SCHUELLER-CHRISTIAN SYNDROME/case reports; SODIUM/blood; THIRST