Renal enlargement in chronic cor pulmonale.
Examination of the post-mortem records of 1,391 unselected cases showed that the commonest condition associated with excessive diffuse enlargement of the kidneys was chronic cor pulmonale. A less striking enlargement was found in some cases of chronic rheumatic heart disease.A hypothesis is put forward in which the renal enlargement is regarded as a work hypertrophy brought about by the kidneys' efforts to compensate for a chronic respiratory acidosis.
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D002908:Chronic Disease; D006801:Humans; D007668:Kidney / Q000473:pathology*; D009205:Myocarditis; D011660:Pulmonary Heart Disease / Q000473:pathology*
KIDNEY/pathology; PULMONARY HEART DISEASE/pathology