The association of increased dihydrofolate reductase with amethopterin resistance in mouse leukemia.
M
M
FRIEDKIN
E
E
CRAWFORD
S R
SR
HUMPHREYS
A
A
GOLDIN
D000818:Animals; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D007938:Leukemia; D007942:Leukemia, Experimental; D008727:Methotrexate; D051379:Mice; D010088:Oxidoreductases / Q000378:metabolism*; D013762:Tetrahydrofolate Dehydrogenase
D005493:Folic Acid Antagonists; D010088:Oxidoreductases; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate
DEHYDROGENASES/metabolism; FOLIC ACID ANTAGONISTS/pharmacology; LEUKEMIA/experimental