Localization of carbonic anhydrase in the nervous system.
Single-cell analyses of carbonic anhydrase demonstrate that this enzyme is selectively concentrated in the glial and choroid cells of the rat brain. The nerve cells show a very low carbonic anhydrase activity. This specific localization supports the view that glial carbonic anhydrase is implicated in a mechanism for the active transport of chloride from the capillaries to the interstitial and cerebrospinal fluids.
GIACOBINI
E
E
D000818:Animals; D001693:Biological Transport, Active; D001921:Brain / Q000378:metabolism*; D002256:Carbonic Anhydrases / Q000378:metabolism*; D009420:Nervous System / Q000378:metabolism*; D009457:Neuroglia; D009474:Neurons; D051381:Rats
D002256:Carbonic Anhydrases
BRAIN/metabolism; CARBONIC ANHYDRASE/metabolism; NERVOUS SYSTEM/metabolism