Effect of amphetamines on speech defects in the mentally retarded.
In a double-blind study, 106 mentally retarded patients with speech defects were given 15 mg. of d-Amphetamine daily, or a placebo, for a three-month period. Speech defect types were: Stuttering, immature production, oral inaccuracy, lisp, psychotic, mongoloid, aphasia, deafness, and cleft palate. Only the stutterers showed obvious improvement in comparison with the placebo group. Three severe, long-term stutterers showed such dramatic improvement that their whole course in life has been changed.
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D000661:Amphetamine / Q000628:therapy*; D001037:Aphasia; D002972:Cleft Palate; D003638:Deafness; D003913:Dextroamphetamine; D004311:Double-Blind Method; D006801:Humans; D008607:Intellectual Disability / Q000628:therapy*; D019989:Persons with Intellectual Disabilities; D011618:Psychotic Disorders; D013060:Speech; D013064:Speech Disorders / Q000628:therapy*; D013342:Stuttering
D000661:Amphetamine; D003913:Dextroamphetamine
AMPHETAMINE/therapy; MENTAL DEFICIENCY/therapy; SPEECH DISORDERS/therapy