The antibacterial activity of a series of quaternaries prepared from hexamethylenetetramine and halohydrocarbons.
A series of quaternaries prepared from hexamethylenetetramine and halohydrocarbons are shown to possess antimicrobial activity which depends upon the slow release of formaldehyde over a wide pH range. The rate of release appears to depend upon the halohydrocarbon moiety to a large extent. Toxicological studies show that these products can be used safely as industrial preservatives for aqueous emulsions such as soluble oils and latex systems.
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D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001419:Bacteria / Q000494:pharmacology*; D005557:Formaldehyde; D006219:Halogens; D006846:Hydrocarbons, Halogenated / Q000494:pharmacology*; D007840:Latex; D008709:Methenamine
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D006219:Halogens; D006846:Hydrocarbons, Halogenated; D007840:Latex; D005557:Formaldehyde; D008709:Methenamine
ANTISEPTICS, HALOGEN/pharmacology; BACTERIA/pharmacology