Thalidomide: effect upon pregnancy in the rhesus monkey.
Thalidomide was administered to 44 female rhesus monkeys immediately after they had mated. There were no live births from these animals, whereas there were 11 live births in 57 untreated monkeys. The results are statistically significant. The hypothesis is advanced that thalidomide killed the embryo prior to implantation.
D000818:Animals; D010064:Embryo Implantation; D005260:Female; D008253:Macaca mulatta; D011247:Pregnancy; D011270:Pregnancy, Animal; D013792:Thalidomide
D013792:Thalidomide
PREGNANCY, ANIMAL; THALIDOMIDE