The relation between urogastrone and gonadotrophins.
A commercial preparation of chorionic gonadotrophin inhibited gastric acid secretion induced by carbachol in rats. When the preparation was incubated for 10 min at 100 degrees C and pH 7, its gonadotrophic activity, as measured by a simple quantal assay based on the male toad spermiation response, was reduced by 92%. The inhibition of gastric acid secretion by the preparation was not significantly reduced by this treatment. It is concluded that the two activities are separable.
D000818:Animals; D001681:Biological Assay; D002217:Carbachol; D006063:Chorionic Gonadotropin; D004815:Epidermal Growth Factor; D005750:Gastric Juice; D005768:Gastrointestinal Hormones; D006062:Gonadotropins; D008297:Male; D051381:Rats
D006063:Chorionic Gonadotropin; D005768:Gastrointestinal Hormones; D006062:Gonadotropins; D004815:Epidermal Growth Factor; D002217:Carbachol
GASTRIC JUICE; GASTROINTESTINAL HORMONES; GONADOTROPINS, CHORIONIC