Inactivation of the T-even coliphages by pyrophosphate.
Van Vunakis, Helen (Brandeis University, Waltham, Mass.) and Roger M. Herriott. Inactivation of the T-even coliphages by pyrophosphate. J. Bacteriol. 83:590-596. 1962.-Pyrophosphate liberates the deoxyribonucleic acid from the T-even coliphages. The reaction is dependent on pH, temperature, time, and ionic environment. The reaction can be inhibited by magnesium, putrescine, spermidine, and neutral molecules above a certain molecular weight. Possible mechanisms of the reaction are discussed.
D001435:Bacteriophages / Q000494:pharmacology*; D003090:Coliphages; D011756:Diphosphates / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D013696:Temperature
D011756:Diphosphates; C107241:diphosphoric acid
BACTERIOPHAGE/pharmacology; PYROPHOSPHATES/pharmacology