Tumors induced in primates by chicken sarcoma virus.
A suspension of a variant of Rous sarcoma was injected into four adult and eight newborn rhesus monkeys. Seven newborns developed tumors, three of which were diagnosed as fibrosarcomas, in 2 to 6 weeks; none of the adults have tumors after 11 weeks. Virus was demonstrated in two of the tumors by injecting a tumor-suspension preparation into the chick wing-web where tumors subsequently appeared. To the best of our knowledge this is the first time that sarcomas have developed in primates after a virus has been injected.
D000818:Animals; D001358:Avian Sarcoma Viruses; D002645:Chickens; D008460:Meat; D009369:Neoplasms; D011323:Primates; D052736:Rous sarcoma virus; D001357:Sarcoma, Avian; D012513:Sarcoma, Experimental
ROUS SARCOMA VIRUS; SARCOMA, EXPERIMENTAL