Terminal oxidation in the regulation of heme biosynthesis.
Turnover of the tricarboxylic acid cycle and the rate of succinyl-coenzyme A formation may be important factors in the regulation of heme biosynthesis in liver homogenate. Acting as hydrogen acceptor, acetoacetate appears to have a unique role in influencing these metabolic processes.
D000090:Acetoacetates; D000214:Acyl Coenzyme A; D002952:Citric Acid Cycle; D006418:Heme; D008099:Liver; D010084:Oxidation-Reduction
D000090:Acetoacetates; D000214:Acyl Coenzyme A; D006418:Heme; C016635:acetoacetic acid; C012046:succinyl-coenzyme A
HEME; KREBS CYCLE; LIVER