Antigenic determinants in fragments of gamma globulin from rabbit serum.
Peptic digestion of fraction III from papain-digested rabbit serum gamma-globulin produces a variety of smaller fragments. Some are too large to pass through a dialysis bag, and these retain the capacity to precipitate with antiserum to rabbit gamma-globulin. Others pass through the bag and fail to precipitate with antibody, but they can inhibit the precipitation of antibody with fraction III. This indicates that antigenic determinants of the gamma-globulin molecule are carried in these fragments.
D000818:Animals; D000906:Antibodies; D000941:Antigens; D000939:Epitopes; D010206:Papain; D011817:Rabbits; D005719:gamma-Globulins
D000906:Antibodies; D000941:Antigens; D000939:Epitopes; D005719:gamma-Globulins; D010206:Papain
ANTIGENS; GAMMA GLOBULIN