Localizing tritiated norepinephrine in sympathetic axons by electron microscopic autoradiography.
Following intravenous infusion of tritiated norepinephrine, rat pineals were prepared for combined autoradiography and electron microscopy. Concentrations of photographic grains were observed only over regions of preterminal autonomic axons containing granulated vesicles, thereby directly demonstrating uptake of norepinephrine into these axons and strongly suggesting that their granulated vesicles contain norepinephrine.
D000818:Animals; D001341:Autonomic Nervous System; D001345:Autoradiography; D001369:Axons; D004583:Electrons; D008853:Microscopy; D008854:Microscopy, Electron; D009638:Norepinephrine; D010870:Pineal Gland; D051381:Rats; D013564:Sympathetic Nervous System
D009638:Norepinephrine
AXONS; MICROSCOPY, ELECTRON; NOREPINEPHRINE; PINEAL BODY; RADIOAUTOGRAPHY; SYMPATHETIC NERVOUS SYSTEM