Enzyme changes in flight muscle correlated with aging and flight ability in the male housefly.
Magnesium-activated adenosine triphosphatase activity in the giant mitochondria (sarcosomes) of the flight muscle of aging male houseflies decreases concomitantly with failure in flight as reflected in the loss of wings during the second week of adult life. Preceding the loss of wings, however, there is a rapid decline in the activity of an alpha-glycerophosphate dehydrogenase which is located in the extramitochondrial fraction and is dependent on nicotinamide adenine dinucleotide.
D000251:Adenosine Triphosphatases; D000375:Aging; D000818:Animals; D005954:Glucosephosphate Dehydrogenase; D005993:Glycerolphosphate Dehydrogenase; D006793:Houseflies; D008297:Male; D008931:Mitochondria, Muscle; D009132:Muscles; D009243:NAD; D014921:Wings, Animal
D009243:NAD; D005993:Glycerolphosphate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D000251:Adenosine Triphosphatases
ADENOSINE TRIPHOSPHATASE; AGING; GLUCOSEPHOSPHATE DEHYDROGENASE; HOUSEFLIES; NAD