Suppression of allergic uveitis by 6-mercaptopurine.
Experimental uveitis in rabbits was induced by single intraocular antigen injection. Treatment with 6-MP for 14 days suppressed the allergic inflammation and antibody response. A good correlation was demonstrated between the degree of uveitis and the antibody titer.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D006967:Hypersensitivity; D015122:Mercaptopurine; D011817:Rabbits; D014605:Uveitis
D000941:Antigens; D015122:Mercaptopurine
ALLERGY; MERCAPTOPURINE; UVEITIS