Treatment of hyperlipemic diabetic patients. Effects of dextro-thyroxine therapy.
Serum low-density lipoproteins of 12 hyperlipemic diabetic patients were lowered, in some cases to normal values, by administration of dextro-thyroxine. Accompanying reductions in serum total cholesterol were largely reflected in the low-density lipoprotein fraction. By contrast, high-density lipoprotein cholesterol concentrations remained relatively unchanged. Diabetic control by insulin or oral hypoglycemic agents was not detectably altered by dextro-thyroxine therapy for periods of 8 to 46 weeks. Therefore, use of the drug for treatment of diabetic hyperlipemia would appear to merit further investigation.
D008076:Cholesterol, HDL; D003920:Diabetes Mellitus; D003924:Diabetes Mellitus, Type 2; D006801:Humans; D006949:Hyperlipidemias; D007004:Hypoglycemic Agents; D007328:Insulin; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D013974:Thyroxine
D008076:Cholesterol, HDL; D007004:Hypoglycemic Agents; D007328:Insulin; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D013974:Thyroxine
DIABETES MELLITUS; HYPERLIPEMIA; THYROXIN