Carbon tetrachloride poisoning in rats: alteration in ribosomes of the liver.
Microsomes from livers of albino rats treated with carbon tetrachloride were compared with those from normal rats with respect to their ability to incorporate amino acid. Acute carbon tetrachloride poisoning results in depressed capacity of microsomes to incorporate amino acid. From ultracentrifugal data, there is an apparent dissociation of 79S ribosomes into 54S components.
D000596:Amino Acids; D000818:Animals; D002252:Carbon Tetrachloride Poisoning; D056486:Chemical and Drug Induced Liver Injury; D008107:Liver Diseases; D008659:Metabolic Diseases; D008861:Microsomes; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D012270:Ribosomes
D000596:Amino Acids; D011506:Proteins
CARBON TETRACHLORIDE POISONING; LIVER DISEASES; PROTEIN METABOLISM DISORDERS