Teratogenic effect of 5-hydroxytryptamine in mice.
The subcutaneous injection of a single dose of 5-hydroxytryptamine into pregnant mice produced a large number of fetal abnormalities, mostly of the eyes, limbs, and tail; the skull and central nervous system were also sometimes affected. These effects could result from the action of the drug on placental function and blood supply.
D000014:Abnormalities, Drug-Induced; D000818:Animals; D000013:Congenital Abnormalities; D005260:Female; D005313:Fetal Death; D051379:Mice; D011247:Pregnancy; D012701:Serotonin; D012886:Skull
D012701:Serotonin
ABNORMALITIES; FETAL DEATH; SEROTONIN