Stimulation and sensitization of the isolated Venus heart by cerebrospinal fluid.
5-Hydroxytryptamine was not detected in animal cerebrospinal fluid after amine oxidase inhibitors, reserpine, or both. Both human and animal cerebrospinal fluid can produce a stimulating effect on the clam heart which is not due to 5-hydroxytryptamine. Cerebrospinal fluid also has the property of increasing the sensitivity of the clam heart to 5-hydroxytryptamine.
D000818:Animals; D002555:Cerebrospinal Fluid; D006321:Heart; D006801:Humans; D008974:Mollusca; D008996:Monoamine Oxidase Inhibitors; D012110:Reserpine; D012701:Serotonin; D018536:Venus
D008996:Monoamine Oxidase Inhibitors; D012701:Serotonin; D012110:Reserpine
CEREBROSPINAL FLUID; HEART; MOLLUSCA; MONOAMINE OXIDASE INHIBITORS; RESERPINE; SEROTONIN