In vitro studies of mammalian somatic cell variation. I. Detection of H-2 phenotype in cultured mouse cell lines.
The isoantigenic phenotype of the H-2 locus has been detected by isohemagglutinin absorption in a line of mouse lymphoma cells growing continuously in culture for 6 years and in two established lines of fibroblastic mouse cells growing continuously in culture for 1 year. Quantitative absorption studies suggest that the concentration of H-2 isoantigens is higher in the cultured lymphoma cells than in the other two fibroblastic cell lines.
D000818:Animals; D001789:Blood Group Antigens; D002460:Cell Line; D002478:Cells, Cultured; D005823:Genetics; D066298:In Vitro Techniques; D007519:Isoantigens; D008223:Lymphoma; D051379:Mice; D009374:Neoplasms, Experimental; D010641:Phenotype; D046509:Tissue Culture Techniques
D001789:Blood Group Antigens; D007519:Isoantigens
BLOOD GROUPS; GENETICS; LYMPHOMA; NEOPLASMS, EXPERIMENTAL; TISSUE CULTURE