TREATMENT OF HYPERTENSION. THE SPECIAL PLACE OF  ALPHA-METHYLDOPA. A SHORT TERM STUDY.
Alpha-methyldopa in amounts of 750 mg twice daily is an effective antihypertensive agent, intermediate in potency between reserpine-thiazide combinations and ganglionic-sympathetic blocking drugs. Because it produces few undesirable side effects, it is well accepted by patients.It is useful for patients with moderate or severe hypertension not controlled by reserpine-thiazide combinations. Its favorable action on cardiac output and renal blood flow provides special advantages for patients with advanced hypertension aggravated by cardiac or renal combinations.
D000959:Antihypertensive Agents; D001795:Blood Pressure Determination; D006801:Humans; D006973:Hypertension; D007677:Kidney Function Tests; D008660:Metabolism; D008750:Methyldopa; D012964:Sodium; D014116:Toxicology
D000959:Antihypertensive Agents; D008750:Methyldopa; D012964:Sodium
ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE DETERMINATION; HYPERTENSION; KIDNEY FUNCTION TESTS; METABOLISM; METHYLDOPA; SODIUM; TOXICOLOGIC REPORT