POLYPEPTIDE CHAINS OF RABBIT GAMMAGLOBULIN.
Rabbit gamma globulin has been extensively reduced, and its polypeptide chains separated by gel filtration on Sephadex G-200 in SM guanidine hydrochloride. The larger H (or A) chains make up two-thirds of the molecule and have a molecular weight of approximately 55,000 each. The smaller L (or B) chains account for the other one-third and have a molecular weight of approximately 25,000 each. The data are consistent with a model of the gamma globulin molecule that has two H and two L chains.
D000818:Animals; D002845:Chromatography; D002850:Chromatography, Gel; D006146:Guanidines; D008970:Molecular Weight; D010455:Peptides; D011817:Rabbits; D012106:Research; D005719:gamma-Globulins
D006146:Guanidines; D010455:Peptides; D005719:gamma-Globulins
CHROMATOGRAPHY; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; GUANIDINES; PEPTIDES; RABBITS