ENZYMATIC REDUCTION OF SELENITE.
Nickerson, Walter J. (Rutgers, The State University, New Brunswick, N.J.) and Giuseppe Falcone. Enzymatic reduction of selenite. J. Bacteriol. 85:763-771.-1963. Extraction of boiled yeast extract with n-hexane removed its ability to restore selenite-reducing capacity in dialyzed enzyme preparations obtained from baker's yeast or from Candida albicans. Menadione or thiodione substituted for the quinone(s) extracted by n-hexane. Active components of the water-soluble, dialyzable fraction of yeast extract included: glucose-6-phosphate, triphosphopyridine nucleotide, and glutathione. Selenite appears to be bound to protein through vicinal thiol groups, and to be released therefrom as metallic selenium after accepting four electrons.
D002175:Candida; D004798:Enzymes; D019298:Glucose-6-Phosphate; D005978:Glutathione; D006586:Hexanes; D008660:Metabolism; D006435:Renal Dialysis; D012440:Saccharomyces; D012441:Saccharomyces cerevisiae; D020887:Selenious Acid; D012643:Selenium; D018036:Selenium Compounds
D004798:Enzymes; D006586:Hexanes; D018036:Selenium Compounds; C026385:n-hexane; D019298:Glucose-6-Phosphate; D020887:Selenious Acid; D005978:Glutathione; D012643:Selenium
CANDIDA; ENZYMES; METABOLISM; SACCHAROMYCES; SELENIUM