ENZYME SYSTEMS IN THE MYCOBACTERIA. XV. INITIAL STEPS IN THE METABOLISM OF GLYCEROL.
Goldman, Dexter S. (Veterans Administration Hospital, Madison, Wis.). Enzyme systems in the mycobacteria. XV. Initial steps in the metabolism of glycerol. J. Bacteriol. 86:30-37. 1963.-In cell-free extracts of strain H37Ra of Mycobacterium tuberculosis, glycerol is metabolized first by oxidation to dihydroxyacetone. A kinase was partially purified and shown to phosphorylate dihydroxyacetone; in the presence of the glyceraldehyde-3-phosphate dehydrogenase system, the product of the kinase reaction was further oxidized to 3-phosphoglycerate. The role of alpha-glycerol phosphate in the metabolism of strain H37Ra is discussed.
D005988:Glyceric Acids; D005990:Glycerol; D008660:Metabolism; D009161:Mycobacterium; D009169:Mycobacterium tuberculosis; D010084:Oxidation-Reduction; D010088:Oxidoreductases; D010770:Phosphotransferases
D005988:Glyceric Acids; C005156:3-phosphoglycerate; D010088:Oxidoreductases; D010770:Phosphotransferases; D005990:Glycerol
GLYCERIN; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PHOSPHOTRANSFERASES