BALANCED INCOMPLETE BLOCK DESIGNS IN BIOLOGICAL ASSAY ILLUSTRATED BY THE ASSAY OF GASTRIN USING A YOUDEN SQUARE.
General equations are given for computing the results of any (j+j) dose parallel line biological assay based on an incomplete block design. Only the information from comparisons within blocks is used. The computation is illustrated numerically by means of a (2+2) assay of gastrin devised and performed by Lai (1962), in which only three of the four doses could be given to each animal.
D000818:Animals; D001681:Biological Assay; D005755:Gastrins; D051381:Rats; D012106:Research
D005755:Gastrins
BIOLOGICAL ASSAY; EXPERIMENTAL LAB STUDY; GASTRIN; RATS