A CONTROLLED TRIAL OF DIGOXIN IN THE PREVENTION OF THE RESPIRATORY DISTRESS SYNDROME.
The possibility that cardiac failure may be an important contributory or additive factor has led to the sporadic use of digitalis in the treatment of the respiratory distress syndrome in newborn infants. To assess the value of such medication a double-blind controlled study was conducted on 196 newborn infants, using digoxin and a placebo. As a result of the findings in this study the routine use of digoxin for the prevention of the respiratory distress syndrome is not recommended. The toxic effects of digitalis are outlined.
D001238:Asphyxia Neonatorum; D004077:Digoxin; D004311:Double-Blind Method; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases; D010919:Placebos; D012128:Respiratory Distress Syndrome; D012127:Respiratory Distress Syndrome, Newborn; D014116:Toxicology
D010919:Placebos; D004077:Digoxin
ASPHYXIA NEONATORUM; DIGOXIN; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; PLACEBOS; TOXICOLOGIC REPORT