ACTIVITY RHYTHM IN PEROMYSCUS: ITS INFLUENCE ON RATES OF RECOVERY FROM NEMBUTAL.
Injection of sublethal doses of Nembutal (sodium pentobarbital) into deer mice, Peromyscus maniculatus rufinus (Merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. By taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased.
D000204:Activity Cycles; D000818:Animals; D001681:Biological Assay; D002940:Circadian Rhythm; D051379:Mice; D010424:Pentobarbital; D010507:Periodicity; D010542:Peromyscus; D010829:Physiological Phenomena; D012106:Research
D010424:Pentobarbital
BIOLOGICAL ASSAY; EXPERIMENTAL LAB STUDY; MICE; PENTOBARBITAL; PERIODICITY