CIRCULARITY OF THE  REPLICATING FORM OF A SINGLE-STRANDED DNA VIRUS.
Electron micrographs of purified replicating form DNA of the bacteriophage øX-174 show that it has ring structure. The circular property may explain both the abnormally high sedimentation coefficient and the great resistance of this DNA to irreversible heat denaturation. Intactness of the circle is required for the control of strand selection during transcription into complementary copies of RNA.
D055598:Chemical Phenomena; D002621:Chemistry; D003090:Coliphages; D004261:DNA Replication; D004267:DNA Viruses; D004277:DNA, Single-Stranded; D004279:DNA, Viral; D004583:Electrons; D008853:Microscopy; D008854:Microscopy, Electron; D012106:Research
D004277:DNA, Single-Stranded; D004279:DNA, Viral
CHEMISTRY; COLIPHAGES; DNA, VIRAL; EXPERIMENTAL LAB STUDY; MICROSCOPY, ELECTRON