HEMOGLOBIN SOLUBILITY AND ALPHA-CHAIN STRUCTURE IN CROSSES BETWEEN TWO INBREAD MOUSE STRAINS.
In genetic crosses between mouse strains with low and high solubilities of hemoglobin, solubility segregated as a Mendelian unit and appeared to be determined by the alleles controlling alpha-chain structure. New data eliminate close linkage between the alpha-chain locus and genetic markers in linkage groups Ill, IV, XI, XIII, and XVI. Simplified methods are presented for screening differences inalpha-chain peptides and solubility.
D000483:Alleles; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D008040:Genetic Linkage; D005819:Genetic Markers; D005823:Genetics; D006454:Hemoglobins; D051379:Mice; D010455:Peptides; D012106:Research; D012995:Solubility
D005819:Genetic Markers; D006454:Hemoglobins; D010455:Peptides
CHEMISTRY; EXPERIMENTAL LAB STUDY; GENETICS; HEMOGLOBIN; MICE