ANTIBODY SUPPRESSION BY ANTIGEN HEAVILY LABELED WITH IODINE-131.
Antibody formation in rabbits was suppressed by tobacco mosaic virus heavily labeled with iodine-131. Animals were injected intravenously with virus containing 0.5 to 4.4 mc of l(131) and after a period of 6 days were challenged with a new antigen, gammaglobulin. Most irradiated animals did not produce detectable antibody. No signs of radiation sickness were noted.
D000818:Animals; D000917:Antibody Formation; D000937:Antigen-Antibody Reactions; D000941:Antigens; D001853:Bone Marrow; D007455:Iodine; D007456:Iodine Isotopes; D008099:Liver; D008168:Lung; D008198:Lymph Nodes; D011817:Rabbits; D012106:Research; D013154:Spleen; D014027:Tobacco Mosaic Virus
D000941:Antigens; D007456:Iodine Isotopes; D007455:Iodine
ANTIBODY FORMATION; ANTIGEN-ANTIBODY REACTIONS; BONE MARROW; EXPERIMENTAL LAB STUDY; IODINE ISOTOPES; LIVER; LUNG; LYMPH NODES; RABBITS; SPLEEN; TOBACCO MOSAIC VIRUS