PLASMA PROTEIN FORMATION IN VITRO BY TISSUES FROM MICE INFECTED WITH STAPHYLOCOCCI.
Isotopic labeling of plasma proteins in vitro by tissues from staphylococcal-infected and control mice was examined, using autoradiography of immunoelectrophoretic patterns. The results indicate that in infected animals there is hyperactivity of liver tissue in producing albumin, alpha- and beta-globulins, and of spleen tissue in producing immune globulins. The observed increase in labeling of some proteins by tissues from infected mice is to a large extent correlated with an increase of these proteins in the serum.
D000818:Animals; D000917:Antibody Formation; D001345:Autoradiography; D001798:Blood Proteins; D002247:Carbon Isotopes; D007122:Immunoelectrophoresis; D066298:In Vitro Techniques; D008099:Liver; D051379:Mice; D010949:Plasma; D011506:Proteins; D012106:Research; D013154:Spleen; D013203:Staphylococcal Infections; D013210:Staphylococcus; D046509:Tissue Culture Techniques
D001798:Blood Proteins; D002247:Carbon Isotopes; D011506:Proteins
BLOOD PROTEINS; CARBON ISOTOPES; EXPERIMENTAL LAB STUDY; IMMUNOELECTROPHORESIS; LIVER; MICE; RADIOAUTOGRAPHY; SPLEEN; STAPHYLOCOCCAL INFECTIONS; TISSUE CULTURE