WASTING DISEASE INDUCED IN YOUNG MICE BY ADMINISTRATION OF CORTISOL ACETATE.
A single injection of cortisol acetate into young mice induced a wasting syndrome similar to that observed in runt disease and in the post-thymectomy syndrome. The course of the disease was less severe if the dose of the drug was decreased or if the animals were older at the time of injection.
D000085:Acetates; D000818:Animals; D002100:Cachexia; D006086:Graft vs Host Disease; D006854:Hydrocortisone / Q000633:toxicity* / Q000031:analogs & derivatives; D008659:Metabolic Diseases; D051379:Mice; D012106:Research; D014116:Toxicology; D019282:Wasting Syndrome
D000085:Acetates; C021650:hydrocortisone acetate; D006854:Hydrocortisone
CACHEXIA; EXPERIMENTAL LAB STUDY; HYDROCORTISONE TOXICOLOGY; METABOLIC DISEASES; MICE; TOXICOLOGIC REPORT