PROPERTIES OF GUINEA PIG 7S ANTIBODIES. V. INHIBITION BY GUINEA PIG GAMMA-2 ANTIBODIES OF PASSIVE IMMUNE LYSIS PROVOKED BY GAMMA-2 ANTIBODIES.
Passive immune lysis of antigen-coated erythrocytes provoked in vitro by guinea pig gamma(2) antihapten antibodies in the presence of complement, is inhibited by guinea pig gamma(1) antibodies directed against the same specificity. This inhibition of the lytic effect of complement-fixing gamma(2) antibodies is presumably due to the competition for antigen by non-lytic gamma(1) antibodies.
D000818:Animals; D000906:Antibodies; D000937:Antigen-Antibody Reactions; D000941:Antigens; D003165:Complement System Proteins; D003602:Cytotoxicity, Immunologic; D006168:Guinea Pigs; D006461:Hemolysis; D012106:Research; D005719:gamma-Globulins
D000906:Antibodies; D000941:Antigens; D005719:gamma-Globulins; D003165:Complement System Proteins
ANTIGEN-ANTIBODY REACTIONS; COMPLEMENT; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; GUINEA PIGS; HEMOLYSIS