GROWTH INHIBITION OF SARCOMA AND CARCINOMA CELLS OF HOMOZYGOUS ORIGIN.
Three sarcomas and one carcinoma, originating in homozygous mice, were tested for growth in isologous animals and various semi-isologous F(1) hybrids after inoculation of 10(3) to 10(5) cells. Findings indicated the existence of an "F(1) hybrid effect" for sarcomas and carcinomas, as previously described for lymphomas and normal hematopoietic cells, there being a lower tumor frequency and a longer latency period in the hybrids than in isologous mice.
D000818:Animals; D001943:Breast Neoplasms; D002277:Carcinoma; D005354:Fibrosarcoma; D006801:Humans; D015674:Mammary Neoplasms, Animal; D008325:Mammary Neoplasms, Experimental; D008748:Methylcholanthrene; D051379:Mice; D009369:Neoplasms / Q000276:immunology*; D012106:Research
D008748:Methylcholanthrene
CARCINOMA; EXPERIMENTAL LAB STUDY; FIBROSARCOMA; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLCHOLANTHRENE; MICE; NEOPLASM IMMUNOLOGY