HYPERBARIC EXPOSURE OF MICE TO PRESSURES OF 60 TO 90 ATMOSPHERES.
Albino mice breathing helium-oxygen mixtures remained in good condition for periods of 1 to 13 hours at pressure-equivalent depths of 396 to 914 meters of sea water. They were successfully decompressed to normal atmospheric pressure in less than 5 hours. There were no immediate or delayed adverse effects that could be attributed to the hyperbaric helium-oxygen environment. An occasional death was attributable to hypoxia or the decompression procedure.
D000818:Animals; D001274:Atmospheric Pressure; D003665:Decompression Sickness; D006931:Hyperbaric Oxygenation; D051379:Mice; D010100:Oxygen; D010102:Oxygen Inhalation Therapy; D010827:Physiology; D011312:Pressure; D051381:Rats; D012106:Research; D012119:Respiration
D010100:Oxygen
ATMOSPHERIC PRESSURE; DECOMPRESSION SICKNESS; EXPERIMENTAL LAB STUDY; HYPERBARIC OXYGENATION; OXYGEN INHALATION THERAPY; PHYSIOLOGY; RATS