[COMPARATIVE EVALUATION OF THE SUBJECTIVE EFFECTS OF DEXTROAMPHETAMINE, METHYLPHENIDATE AND PLACEBO].
The subjective effects of dextroamphetamine, methylphenidate and placebo were evaluated in 16 medical students during the period just prior to their final oral examinations. The subjects served as their own controls. The order of administration of the three medications for each student was randomized, and a double-blind technique was used throughout. A questionnaire method was employed for the collection of results, which proved to be a useful and effective means. It demonstrated that dextroamphetamine, methylphenidate and placebo were statistically different from one another with regard to their effect on efficiency of studying, fatigue, duration of sleep and appetite. There were also significant differences in the number of side effects caused by the three medications. The stimulants, however, did not increase the number of study hours, nor was their use recommended by the students when preparing for important examinations.
D001066:Appetite; D035843:Biomedical Research; D000697:Central Nervous System Stimulants; D003913:Dextroamphetamine; D004311:Double-Blind Method; D005221:Fatigue; D006801:Humans; D007858:Learning; D008774:Methylphenidate; D010600:Pharmacology; D010919:Placebos; D012890:Sleep; D013223:Statistics as Topic; D013334:Students; D014116:Toxicology
D000697:Central Nervous System Stimulants; D010919:Placebos; D008774:Methylphenidate; D003913:Dextroamphetamine
APPETITE; CLINICAL RESEARCH; DEXTRO AMPHETAMINE; FATIGUE; LEARNING; METHYLPHENIDATE; PHARMACOLOGY; PLACEBOS; SLEEP; STATISTICS; STUDENTS; TOXICOLOGIC REPORT
EVALUATION COMPAR'EE DES EFFETS SUBJECTIFS DE LA DEXTROAMPH'ETAMINE, DU M'ETHYLPH'ENIDATE ET DU PLACEBO.