LYMPHOID ORGANS AND NORMAL GAMMA-GLOBULIN IN THE RAT.
Serum gamma-globulin was determined in adult rats several months after total thymectomy, subtotal splenectomy, or a combination of total thymectomy, subtotal splenectomy, and subtotallymphadenectomy. The thymus apparently is of little importance in the production of normal gamma-globulin, but it may influence the production of albumin because a reduction of serum albumin was only seen in groups where thymectomy was performed. The spleen seems to produce normal gamma-globulin to a greater extent than lymphoid tissue elsewhere in the body.
D000510:Alpha-Globulins; D001609:Beta-Globulins; D007136:Immunoglobulins; D008197:Lymph Node Excision; D008221:Lymphoid Tissue; D010827:Physiology; D051381:Rats; D012106:Research; D012709:Serum Albumin; D013154:Spleen; D013156:Splenectomy; D013934:Thymectomy; D013950:Thymus Gland; D005719:gamma-Globulins
D000510:Alpha-Globulins; D001609:Beta-Globulins; D007136:Immunoglobulins; D012709:Serum Albumin; D005719:gamma-Globulins
ALPHA GLOBULIN; BETA GLOBULIN; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; LYMPH NODE EXCISION; LYMPHOID TISSUE; PHYSIOLOGY; RATS; SERUM ALBUMIN; SPLENECTOMY; THYMECTOMY; THYMUS GLAND