PSYCHOLOGICAL CHANGES ASSOCIATED WITH INDUCED HYPERAMMONEMIA.
Normal volunteers infused with ammonium acetate for 3 hours developed a characteristic behavior pattern resembling that of prehepatic coma. They demonstrated certain specific defects in motor performance and recognition aswell as significant lowering of critical flicker fusion. These findings arecorrelated with the concentration of ammonia in arterial blood.
D064751:Ammonium Compounds; D001519:Behavior; D035843:Biomedical Research; D001769:Blood; D005425:Flicker Fusion; D006501:Hepatic Encephalopathy; D006801:Humans; D022124:Hyperammonemia; D009048:Motor Skills; D010465:Perception; D010919:Placebos; D000644:Quaternary Ammonium Compounds; D014116:Toxicology; D014796:Visual Perception
D064751:Ammonium Compounds; D010919:Placebos; D000644:Quaternary Ammonium Compounds
AMMONIUM COMPOUNDS; BEHAVIOR; BLOOD; CLINICAL RESEARCH; FLICKER FUSION; HEPATIC COMA; MOTOR SKILLS; PERCEPTION; PLACEBOS; TOXICOLOGIC REPORT; VISUAL PERCEPTION