EFFECTS OF GASTRIC FREEZING ON THE ISOLATED DENERVATED GASTRIC POUCH IN DOGS.
The purpose of this study was to investigate the effects of gastric freezing on the chief and parietal cells of the stomach. To carry this out six Heidenhain pouch dogs were prepared. The secretions of these pouches were studied, both for HCl levels and pepsin activity, for 30 days before and 30 days after the freezing of the pouch. Freezing was carried out for one hour at -17 to -20 degrees C. The results show that no essential depression of either the HCl levels or the pepsin activity of the juice was effected by freezing. Therefore, it is deduced that freezing does not affect the functional activity of either the chief or the parietal cells. Complications such as ulceration and fistula formation into adjacent organs occurred as a result of freezing in certain pouch dogs.
D000818:Animals; D002415:Cats; D003452:Cryosurgery; D004285:Dogs; D005615:Freezing; D005745:Gastric Acidity Determination; D005747:Gastric Fistula; D050786:Gastric Hypothermia; D005750:Gastric Juice; D006851:Hydrochloric Acid; D010295:Parietal Cells, Gastric; D010434:Pepsin A; D010438:Peptic Ulcer Hemorrhage; D010827:Physiology; D012106:Research; D013270:Stomach; D013276:Stomach Ulcer
D010434:Pepsin A; D006851:Hydrochloric Acid
CATS; CRYOGENIC SURGERY; DOGS; EXPERIMENTAL LAB STUDY; GASTRIC ACIDITY DETERMINATION; GASTRIC FISTULA; GASTRIC JUICE; HYDROCHLORIC ACID; PEPSIN; PEPTIC ULCER HEMORRHAGE; PHYSIOLOGY; STOMACH; STOMACH ULCER