MICROBIAL HYDROXYLATION OF INDOLE ALKALOIDS.
The hydroxylation of the indole-type alkaloids, yohimbine, alpha-yohimbine, beta-yohimbine, and corynanthine, was achieved with several genera of higher fungi and species of Streptomyces. Microorganisms were found which monohydroxylated these compounds in three different positions. The site of hydroxylation was strain-specific for two strains of Cunninghamella echinulata and C. bainieri.
D000470:Alkaloids; D020093:Cunninghamella; D005658:Fungi; D006900:Hydroxylation; D007211:Indoles; D012106:Research; D013302:Streptomyces; D015016:Yohimbine
D000470:Alkaloids; D007211:Indoles; D015016:Yohimbine
ALKALOIDS; EXPERIMENTAL LAB STUDY; FUNGI; INDOLES; STREPTOMYCES; YOHIMBINE