title: HISTOCHEMICAL DEMONSTRATION OF UPTAKE OF EXOGENOUS NOREPINEPHRINE BY ADRENERGIC FIBERS IN VITRO.
abstract: Adrenergic fibers in isolated iris preparations were demonstrated histochemically by means of the formaldehyde condensation technique. In the presence of adenosine triphosphate (ATP) there was a net uptake of norepinephrine added in vitro by the adrenergic fibers producing a striking increase in fluorescence. In the absence of ATP only a slight increase in fluorescence was observed when the tissue was exposed to high concentrations of norepinephrine.
mesh_terms: D000255:Adenosine Triphosphate; D000320:Adrenergic Fibers; D005453:Fluorescence; D005557:Formaldehyde; D006651:Histocytochemistry; D066298:In Vitro Techniques; D007498:Iris; D008853:Microscopy; D008856:Microscopy, Fluorescence; D009411:Nerve Endings; D009638:Norepinephrine; D010600:Pharmacology; D051381:Rats; D012106:Research; D013564:Sympathetic Nervous System
chemical_list: D005557:Formaldehyde; D000255:Adenosine Triphosphate; D009638:Norepinephrine
keywords: ADENOSINE TRIPHOSPHATE; EXPERIMENTAL LAB STUDY; FORMALDEHYDE; HISTOCYTOCHEMISTRY; IRIS; MICROSCOPY, FLUORESCENCE; NERVE ENDINGS; NOREPINEPHRINE; PHARMACOLOGY; RATS; SYMPATHETIC NERVOUS SYSTEM