REDIFFERENTIATION OF CONNECTIVE TISSUE CELLS IN SERIAL CULTURE.
When cell cultures are initiated from aortic connective tissue of rats and maintained as monolayers on glass, the differentiated property of collagen production disappears. However, these same cells, when placed in diffusion chambers in the peritoneal cavities of other rats, produce collagen, as indicated both morphologically and by the accumulation of hydroxy-proline within the chambers.
D001011:Aorta; D003094:Collagen; D003238:Connective Tissue; D003239:Connective Tissue Cells; D006909:Hydroxyproline; D011392:Proline; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D012106:Research; D046509:Tissue Culture Techniques
D011506:Proteins; D003094:Collagen; D011392:Proline; D006909:Hydroxyproline
AORTA; COLLAGEN; CONNECTIVE TISSUE; EXPERIMENTAL LAB STUDY; HYDROXYPROLINE; PROTEIN METABOLISM; RATS; TISSUE CULTURE