INHIBITION OF SPECIFIC BINDING OF ANTIBODY TO THE RHO(D) FACTOR OF RED CELLS IN ANTIBODY EXCESS.
The uptake by red cells of I(131)-labeled nonagglutinating antibody to the Rh(0)(D) factor was dependent on the proportion of cells to antibody during sensitization. Inhibition of antibody binding by red cells in the region of antibody excess occurred with Rh(0)(D) positive red cells that were both papain modified and untreated; the inhibition was independent of the Rh phenotype.
D000906:Antibodies; D000937:Antigen-Antibody Reactions; D004912:Erythrocytes; D006801:Humans; D007456:Iodine Isotopes; D012106:Research; D012204:Rh-Hr Blood-Group System
D000906:Antibodies; D007456:Iodine Isotopes; D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen
ANTIGEN-ANTIBODY REACTIONS; ERYTHROCYTES; EXPERIMENTAL LAB STUDY; IODINE ISOTOPES; RH FACTORS