title: PALLIATIVE MANAGEMENT OF GASTROINTESTINAL CANCER.
abstract: Much can be achieved in the management of and treatment of the complications of metastatic gastrointestinal cancer. Ascites accompanied by identifiable malignant cells frequently can be controlled by intraperitoneal chemotherapy. The symptoms of a deficiency anemia may be relieved by suitable replacement therapy. Radiotherapy may relieve dysphagia. There is no single effective remedy for persistent hiccups; some of the commonly used measures are described. 5-Fluorouracil (5 FU) is the first chemotherapeutic agent found to have a significant effect on gastrointestinal adenocarcinoma. Treatment may be accompanied by severe toxicity and should be administered in hospital by experienced chemotherapists. Radiotherapy may relieve perineal pain, tenesmus, dysphagia and discharge.
mesh_terms: D000230:Adenocarcinoma; D001201:Ascites; D003680:Deglutition Disorders; D005472:Fluorouracil; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000532:radiotherapy*; D012004:Rectal Neoplasms; D013274:Stomach Neoplasms; D013852:Thiotepa
chemical_list: D013852:Thiotepa; D005472:Fluorouracil
keywords: ASCITES; DEGLUTITION DISORDERS; FLUOROURACIL; NEOPLASM METASTASIS; NEOPLASM RADIOTHERAPY; RECTAL NEOPLASMS; STOMACH NEOPLASMS; THIO-TEPA