REDUCTION OF CARDIAC STORES OF NOREPINEPHRINE IN EXPERIMENTAL HEART FAILURE.
Constriction of the ascending aorta in the guinea pig resulted in ventricular hypertrophy and congestive heart failure. In animals with heart failure which were killed 5 to 40 days after constriction, the norepinephrine stores in both ventricles were strikingly reduced; the extent of reduction was related to the severity of the constriction.
D000818:Animals; D001011:Aorta; D001013:Aorta, Thoracic; D006332:Cardiomegaly; D003250:Constriction; D006168:Guinea Pigs; D006321:Heart; D006333:Heart Failure; D006352:Heart Ventricles; D007668:Kidney; D008660:Metabolism; D009206:Myocardium; D009638:Norepinephrine; D012106:Research
D009638:Norepinephrine
AORTA, THORACIC; EXPERIMENTAL LAB STUDY; GUINEA PIGS; HEART ENLARGEMENT; HEART FAILURE, CONGESTIVE; KIDNEY; METABOLISM; MYOCARDIUM; NOREPINEPHRINE