title: INDEPENDENT ACTION OF  ALLELE-SPECIFIC SUPPRESSOR MUTATIONS.
abstract: Two different allele-specific suppressor genes had an independent and nonadditive effect in restoring indoleglycerol phosphate --> L-tryptophan activity in a double mutant strain lacking this activity.
mesh_terms: D000483:Alleles; D002875:Chromosomes; D004926:Escherichia coli; D005994:Glycerophosphates; D007211:Indoles; D008025:Ligases; D008660:Metabolism; D009154:Mutation; D011506:Proteins / Q000378:metabolism*; D012106:Research; D013489:Suppression, Genetic; D014364:Tryptophan
chemical_list: D005994:Glycerophosphates; D007211:Indoles; D011506:Proteins; C008117:indoleglycerol phosphate; D014364:Tryptophan; D008025:Ligases
keywords: CHROMOSOMES; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; GLYCEROPHOSPHATES; INDOLES; LIGASES; METABOLISM; MUTATION; PROTEIN METABOLISM; TRYPTOPHAN