title: DIPHTHERIA ANTITOXIN: ANTIGEN-COMBINING AND TOXIN-NEUTRALIZING PROPERTIES OF PAPAIN FRAGMENTS.
abstract: Papain-digested rabbit antibodies to diphtheria toxoid were separated into three fragments. Fragments I and II combined with toxoid in vitro and neutralized toxin. The ratios of these activities were not the same for fragments I and II, indicating that antitoxic and accessory antibody may be distributed unequally between two classes of antibody.
mesh_terms: D000818:Animals; D000906:Antibodies; D004166:Diphtheria Antitoxin; D007106:Immune Sera; D010206:Papain; D011817:Rabbits; D012106:Research; D014118:Toxins, Biological; D005719:gamma-Globulins
chemical_list: D000906:Antibodies; D004166:Diphtheria Antitoxin; D007106:Immune Sera; D014118:Toxins, Biological; D005719:gamma-Globulins; D010206:Papain
keywords: DIPHTHERIA ANTITOXIN; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; IMMUNE SERUMS; PAPAIN; RABBITS