title: ELECTROPHORUS ADENOSINE TRIPHOSPHATASE: SODIUM-ACTIVATED EXCHANGE AFTER N-ETHYLALEIMIDE TREATMENT.
abstract: The microsomal fraction from the electric organ of the eel Electrophorus electricus catalyzes the hydrolysis of adenosine triphosphate in the presence of Mg(++), Na(+), and K(+). The same preparation catalyzes a Mg(++)-dependent transphosphorylation between adenosine triphosphate and adenosine diphosphate. Both of these reactions are inhibited after treatment of the microsomes with N-ethyl maleimide. However, the addition of Na(+) reactivates the transphosphorylation, and the rate becomes more rapid than that of the original. This new Na(+)-sensitive exchange reaction is believed to be a component of the hydrolytic reaction.
mesh_terms: D000244:Adenosine Diphosphate; D000251:Adenosine Triphosphatases; D000255:Adenosine Triphosphate; D000818:Animals; D002712:Chlorides; D004524:Eels; D004557:Electric Organ; D004593:Electrophorus; D007477:Ions; D008094:Lithium; D008274:Magnesium; D008861:Microsomes; D010600:Pharmacology; D011188:Potassium; D011758:Pyrroles; D012106:Research; D012964:Sodium; D012965:Sodium Chloride
chemical_list: D002712:Chlorides; D007477:Ions; D011758:Pyrroles; D012965:Sodium Chloride; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D008094:Lithium; D012964:Sodium; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium
keywords: ADENOSINE TRIPHOSPHATASE; CHLORIDES; EELS; ELECTRIC ORGAN; EXPERIMENTAL LAB STUDY; LITHIUM; MAGNESIUM; PHARMACOLOGY; POTASSIUM; PYRROLES; SODIUM CHLORIDE