title: BINDING OF AN ALPHA GLOBULIN TO HYALURONATEPROTEIN IN PATHOLOGICAL SYNOVIAL FLUIDS.
abstract: Rabbits were immunized with hyaluronateprotein isolated from normal or pathological synovial fluids. Immunoelectrophoresis of hyaluroni-dase-digested pathological hyaluronateprotein and its antiserum showed a single precipitin arc extending through both alpha globulin zones. Digested normal hyaluronateprotein formed no lines with either its antiserum or with that to pathological hyaluronateprotein. The antigenic component present in pathological hyaluronateprotein formed a reaction of complete fusion with a serum protein which was identified by immunoelectrophoresis as an alpha globulin.
mesh_terms: D000510:Alpha-Globulins; D000818:Animals; D000937:Antigen-Antibody Reactions; D001798:Blood Proteins; D006820:Hyaluronic Acid; D007106:Immune Sera; D007122:Immunoelectrophoresis; D011233:Precipitin Tests; D011506:Proteins; D011817:Rabbits; D012106:Research; D012712:Serum Globulins; D013582:Synovial Fluid
chemical_list: D000510:Alpha-Globulins; D001798:Blood Proteins; D007106:Immune Sera; D011506:Proteins; D012712:Serum Globulins; D006820:Hyaluronic Acid
keywords: ALPHA GLOBULIN; ANTIGEN-ANTIBODY REACTIONS; EXPERIMENTAL LAB STUDY; HYALURONIC ACID; IMMUNOELECTROPHORESIS; PRECIPITIN TESTS; PROTEINS; RABBITS; SERUM GLOBULINS; SYNOVIAL FLUID