title: RADIATION ACTION ON DNA IN BACTERIA: EFFECT OF OXYGEN.
abstract: In Escherichia coli cells ionizing radiation produces a degradation of DNA to approximately 50 percent of the total amount originally insoluble in trichloroacetic acid. There is also a reduction of synthesis. Oxygen inhibits the degradation process by a dose reduction factor of 4 and the synthesis process by a factor of approximately 1.5. Thus, at relatively low doses, radiation action on bacteria is very probably mediated through the DNA.
mesh_terms: D002247:Carbon Isotopes; D003036:Cobalt Isotopes; D004247:DNA; D004269:DNA, Bacterial; D004926:Escherichia coli; D008660:Metabolism; D009584:Nitrogen; D010100:Oxygen; D011830:Radiation Effects; D012106:Research; D013941:Thymine
chemical_list: D002247:Carbon Isotopes; D003036:Cobalt Isotopes; D004269:DNA, Bacterial; D004247:DNA; D009584:Nitrogen; D013941:Thymine; D010100:Oxygen
keywords: CARBON ISOTOPES; COBALT ISOTOPES; DNA, BACTERIAL; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; METABOLISM; NITROGEN; OXYGEN; RADIATION EFFECTS; THYMINE