THYMECTOMY: EFFECT ON SECONDARY DISEASE IN RADIATION CHIMERAS.
The pattern of secondary mortality in mice after irradiation and hemopoietic cell transplantation was changed by thymectomy of the recipients 3 weeks before irradiation. In isologous and parent-to-F(1) chimeras excess mortality was occurring later than the usual period of secondary disease. In thymectomized heterologous chimeras secondary mortality was decreased and delayed
D000818:Animals; D000831:Animals, Newborn; D016026:Bone Marrow Transplantation; D007109:Immunity; D008099:Liver; D051379:Mice; D011828:Radiation Chimera; D011830:Radiation Effects / Q000276:immunology*; D012106:Research; D016038:Skin Transplantation; D013934:Thymectomy; D013950:Thymus Gland; D014180:Transplantation; D014181:Transplantation Immunology
ANIMALS, NEWBORN; BONE MARROW TRANSPLANTATION; EXPERIMENTAL LAB STUDY; IMMUNITY; LIVER; MICE; RADIATION IMMUNOLOGY; THYMECTOMY; THYMUS GLAND; TRANSPLANTATION; TRANSPLANTATION IMMUNOLOGY