title: HUMAN ERYTHROCYTE LACTATE DEHYDROGENASE: 4 GENETICALLY DETERMINED VARIANTS.
abstract: Four variants of human erythrocyte lactate dehydrogenase (LDH) are described. One of these is similar to the one previously described by Boyer and is interpreted as a variant of LDH-B. The other three are thought to represent variants of LDH-A. Studies of families indicate that LDH-A and LDH-B are under separate genetic control and are inherited as autosomal co-dominants. Evidence is presented that the LDH-A locus is not closely linked to the loci for the ABH and Duffy blood group systems.
mesh_terms: D035843:Biomedical Research; D004586:Electrophoresis; D004912:Erythrocytes; D014644:Genetic Variation; D005826:Genetics, Medical; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D000080864:Lactate Dehydrogenase 5
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D000080864:Lactate Dehydrogenase 5; C409667:lactate dehydrogenase 1
keywords: CLINICAL RESEARCH; ELECTROPHORESIS; ERYTHROCYTES; GENETICS, HUMAN; LACTATE DEHYDROGENASE