HOST CELL SPECIES SPECIFICITY OF MOUSE AND CHICKEN INTERFERONS.
Three thousand units of mouse interferon and 2000 units of chicken interferon were assayed on the respective heterologous species cell cultures. No antiviral activity was observed in the heterologous systems, suggesting a virtually complete species barrier to the action of these interferons
D000818:Animals; D000998:Antiviral Agents; D002642:Chick Embryo; D002645:Chickens; D004622:Embryo, Mammalian; D004625:Embryo, Nonmammalian; D058507:Host Specificity; D007159:Immunologic Tests; D007372:Interferons; D051379:Mice; D009522:Newcastle disease virus; D009975:Orthomyxoviridae; D010600:Pharmacology; D010828:Physiology, Comparative; D011200:Poultry; D012106:Research; D013045:Species Specificity; D046509:Tissue Culture Techniques; D014776:Virus Cultivation
D000998:Antiviral Agents; D007372:Interferons
CHICK EMBRYO; EMBRYO; EXPERIMENTAL LAB STUDY; INFLUENZA VIRUSES; INTERFERON; MICE; NEWCASTLE DISEASE VIRUS; PHARMACOLOGY; PHYSIOLOGY, COMPARATIVE; POULTRY; SPECIES SPECIFICITY; TISSUE CULTURE; VIRUS CULTIVATION