URACIL: FAILURE TO RESTORE DNA SYNTHESIS WHILE RELIEVING 5-FLUOROURACIL-INDUCED INHIBITION.
Growth inhibition of Bacillus cereus by 5-fluorouracil is abolished by the addition of uracil without the inhibition of DNA synthesis being relieved. The growth rate, protein, and RNA content of cells grown in the presence of 5-fluorouracil and uracil are unaffected until the cells contain only about 25 percent of their normal DNA content.
D000225:Adenine; D001409:Bacillus cereus; D002247:Carbon Isotopes; D004247:DNA; D004269:DNA, Bacterial; D005472:Fluorouracil; D005561:Formates; D006147:Guanine; D007042:Hypoxanthines; D008660:Metabolism; D010600:Pharmacology; D011506:Proteins; D012313:RNA; D012106:Research; D014498:Uracil
D002247:Carbon Isotopes; D004269:DNA, Bacterial; D005561:Formates; D007042:Hypoxanthines; D011506:Proteins; D014498:Uracil; D006147:Guanine; D012313:RNA; D004247:DNA; D000225:Adenine; D005472:Fluorouracil
ADENINE; BACILLUS CEREUS; CARBON ISOTOPES; DNA, BACTERIAL; EXPERIMENTAL LAB STUDY; FLUOROURACIL; FORMATES; GUANINE; HYPOXANTHINES; METABOLISM; PHARMACOLOGY; URACIL