GAMMA GLOBULIN: UNMASKING OF HIDDEN  ANTIGENIC SITES ON LIGHT CHAINS.
Normal light (L) chains cleaved from normal pooled human gamma globulin contain immunologic determinants not overtly present in the native unreduced molecule. These hidden determinants are shared with Bence Jones proteins. Similarly, one of two Bence Jones proteins contained immunologic determinants which were not overtly present on the autologous serum myeloma protein.
D000941:Antigens; D001536:Bence Jones Protein; D006801:Humans; D005779:Immunodiffusion; D009101:Multiple Myeloma; D010455:Peptides; D011233:Precipitin Tests; D012106:Research; D005719:gamma-Globulins
D000941:Antigens; D010455:Peptides; D005719:gamma-Globulins; D001536:Bence Jones Protein
ANTIGENS; BENCE JONES PROTEIN; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; GEL DIFFUSION TESTS; PRECIPITIN TESTS