title: ELECTRON MICROSCOPIC AND BIOCHEMICAL STUDIES OF PYRUVATE DEHYDROGENASE COMPLEX OF ESCHERICHIA COLI.
abstract: Examination with the electron microscope of the pyruvate dehydrogenase complex and its component enzymes from Escherichia coli indicates that the complex has a polyhedral structure with a diameter of about 300 to 350 angstroms and a height of 200 to 250 angstroms. The reconstituted complex closely resembles the native complex in appearance. A tentative model of this multienzyme complex is proposed on the basis of the correlated biochemical and electron-microscopic data
mesh_terms: D000085:Acetates; D000217:Acyltransferases; D002262:Carboxy-Lyases; D004396:Coloring Agents; D004583:Electrons; D004926:Escherichia coli; D008853:Microscopy; D008854:Microscopy, Electron; D010088:Oxidoreductases; D010772:Phosphotungstic Acid; D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D012106:Research; D013194:Staining and Labeling; D008063:Thioctic Acid
chemical_list: D000085:Acetates; D004396:Coloring Agents; D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D010772:Phosphotungstic Acid; D008063:Thioctic Acid; D010088:Oxidoreductases; D000217:Acyltransferases; D002262:Carboxy-Lyases
keywords: ACETATES; ACYLTRANSFERASES; CARBOXY-LYASES; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; LIPOIC ACID; MICROSCOPY, ELECTRON; OXIDOREDUCTASES; PHOSPHOTUNGSTIC ACID; PYRUVATES; STAINS AND STAINING