DNA SYNTHESIS IN ALVEOLAR CELLS OF THE MAMMARY GLAND: ACCELERATION BY OVARIAN HORMONES.
In normal alveolar cells of the mammary gland of C3H/HeJ female mice, DNA synthesis lasts an average of 20.7 hours with a coefficient of variation of 26.6 percent. Treatment of the mice with I microgram of 17-beta-estradiol and 1 milligram of progesterone per day for 3 to 4 days decreases the average duration to 10.7 hours and the coefficient of variation to 13.8 percent.
D056809:Alveolar Epithelial Cells; D000818:Animals; D004247:DNA; D004958:Estradiol; D005260:Female; D006801:Humans; D008321:Mammary Glands, Animal; D042361:Mammary Glands, Human; D008660:Metabolism; D051379:Mice; D008809:Mice, Inbred C3H; D008815:Mice, Inbred Strains; D010600:Pharmacology; D011374:Progesterone; D012106:Research; D013936:Thymidine; D014316:Tritium
D014316:Tritium; D011374:Progesterone; D004958:Estradiol; D004247:DNA; D013936:Thymidine
DNA; ESTRADIOL; EXPERIMENTAL LAB STUDY; MAMMAE; METABOLISM; MICE; PHARMACOLOGY; PROGESTERONE; THYMIDINE; TRITIUM