title: HETEROGENEITY OF THE INHERITED GROUP-SPECIFIC COMPONENT OF HUMAN SERUM.
abstract: Heterogeneity of the group-specific (Gc) components in normal human serum has been demonstrated by the use of a lithium borate buffer system in conventional vertical starch gel electrophoresis and by prolonged immunoelectrophoresis in agar gel. In both Gc 1-1 and Gc 2-2 phenotypes a protein component migrates ahead of the main band. Immunological evidence indicates that the faster migrating band contains Gc specificity. The possibility that the two electrophoretically distinct Gc components share a common polypeptide chain is discussed.
mesh_terms: D001789:Blood Group Antigens; D001797:Blood Protein Electrophoresis; D005826:Genetics, Medical; D006801:Humans; D007122:Immunoelectrophoresis; D010455:Peptides; D010641:Phenotype
chemical_list: D001789:Blood Group Antigens; D010455:Peptides
keywords: BLOOD GROUPS; BLOOD PROTEIN ELECTROPHORESIS; GENETICS, HUMAN; IMMUNOELECTROPHORESIS