TREMORINE: ITS PERIPHERAL ACTION ON STRIATED MUSCLE.
Tremorine, injected intraperitoneally into rats, induces the same kind of calcium release in the motor end-plates as that induced by acetylcholine-like agents. Since the same effect results even if the appropriate motor nerve has previously been transected, it is concluded that this myoneural action of Tremorine is not due to a e entral excitation but rather to a peripheral stimulatory property of the drug.
D000109:Acetylcholine; D002118:Calcium / Q000378:metabolism*; D018482:Muscle, Skeletal; D054792:Muscle, Striated; D009132:Muscles; D009469:Neuromuscular Junction; D010600:Pharmacology; D011758:Pyrroles; D051381:Rats; D012106:Research; D014202:Tremor; D014203:Tremorine
D011758:Pyrroles; D000109:Acetylcholine; D002118:Calcium; D014203:Tremorine
CALCIUM METABOLISM; EXPERIMENTAL LAB STUDY; MUSCLES; NEUROMUSCULAR JUNCTION; PHARMACOLOGY; PYRROLES; RATS; TREMOR