FRUCTOSE-1,6-DIPHOSPHATE REQUIREMENT OF STREPTOCOCCAL LACTIC DEHYDROGENASES.
The lactic dehydrogenase of a strain of Streptococcus bovis specifically requires fructose-1,6-diphosphate for activity. Phosphate or fructose-1-6-diphosphate prevents inactivation of the dehydrogenase, but phosphate and other compounds cannot be substituted for the fructose-1,6-diphosphate required for activity. Lactic dehydrogenases of other species of Streptococcus show a similar requirement for fructose-1,6-diphosphate.
D011756:Diphosphates; D005632:Fructose; D005635:Fructosediphosphates; D006600:Hexosephosphates; D007770:L-Lactate Dehydrogenase; D010088:Oxidoreductases; D010710:Phosphates; D012106:Research; D013291:Streptococcus
D011756:Diphosphates; D005635:Fructosediphosphates; D006600:Hexosephosphates; D010710:Phosphates; D005632:Fructose; D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; C029063:fructose-1,6-diphosphate
EXPERIMENTAL LAB STUDY; HEXOSEPHOSPHATES; LACTATE DEHYDROGENASE; STREPTOCOCCUS