title: THE EVALUATION AND MODIFICATION OF A TECHNIQUE FOR COMPARING THE EFFICIENCY OF ANTISEPTICS AGAINST SUBCUTANEOUSLY DEPOSITED BACTERIA IN MICE.
abstract: An attempt has been made to study the action of antiseptics on artificial streptococcal ;wounds' in mice by a published technique (Martin, 1959). The results were not in agreement with those of Martin and the possible reasons for this are discussed. Suggestions are made for modifying the original method to increase its scope and precision. The production and treatment of Ps. pyocyanea and Kl. aerogenes ;wounds' in mice is described and discussed.
mesh_terms: D064751:Ammonium Compounds; D000818:Animals; D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D001419:Bacteria; D000431:Ethanol / Q000031:analogs & derivatives; D007709:Klebsiella; D051379:Mice; D010600:Pharmacology; D011552:Pseudomonas Infections; D000644:Quaternary Ammonium Compounds; D012106:Research; D013290:Streptococcal Infections; D013501:Surface-Active Agents
chemical_list: D064751:Ammonium Compounds; D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; C062527:tribromoethanol; D000431:Ethanol
keywords: ANTI-INFECTIVE AGENTS, LOCAL; ANTISEPTICS, QUATERNARY AMMONIUM; EXPERIMENTAL LAB STUDY; KLEBSIELLA; MICE; PHARMACOLOGY; PSEUDOMONAS INFECTIONS; STREPTOCOCCAL INFECTIONS; SURFACE-ACTIVE AGENTS; TRIBROMOETHANOL