title: EFFECTS OF ASPARTATE ON GROWTH AND ON THE SYNTHESIS OF ALPHA-AMYLASE IN PSEUDOMONAS SACCHAROPHILA.
abstract: Eisenstadt, Jerome M. (Brandeis University, Waltham, Mass.), and Harold P. Klein. Effects of aspartate on growth and on the synthesis of alpha-amylase in Pseudomonas saccharophila. J. Bacteriol. 87:1355-1363. 1964.-Protein synthesis by starch-grown cells of Pseudomonas saccharophila is inhibited by low concentrations of d-aspartate, whereas assimilation continues for several hours under these conditions. These effects are also observed when the cells are grown with cellobiose or maltose, but not with a wide variety of other carbon sources. l-Aspartate at a ratio of about 6:1 completely reverses these effects, whereas adenosine partially does so. One possible basis of the inhibitory effects of d-aspartate is in the synthesis of adenosine from inosine.
mesh_terms: D000681:Amylases; D001224:Aspartic Acid; D002244:Carbon; D042621:Comamonadaceae; D008320:Maltose; D008660:Metabolism; D010600:Pharmacology; D011506:Proteins / Q000378:metabolism*; D011549:Pseudomonas; D012106:Research; D013213:Starch; D000516:alpha-Amylases
chemical_list: D011506:Proteins; D001224:Aspartic Acid; D008320:Maltose; D002244:Carbon; D013213:Starch; D000681:Amylases; D000516:alpha-Amylases
keywords: AMYLASE; ASPARTIC ACID; EXPERIMENTAL LAB STUDY; METABOLISM; PHARMACOLOGY; PROTEIN METABOLISM; PSEUDOMONAS