CONGENITAL AORTIC STENOSIS: SOME OBSERVATIONS ON THE NATURAL HISTORY AND CLINICAL ASSESSMENT.
Three hundred patients, 30 years of age or under, with the clinical diagnosis of aortic stenosis were reviewed to provide information on the accuracy of clinical assessment and the natural history of the condition when left untreated. Sudden death was uncommon and occurred only in patients with clinical evidence of severe obstruction. In infants, the early presentation and lethal nature of aortic stenosis appeared to result from the presence of additional cardiac lesions. Correlation of clinical assessment with hemodynamic data in 83 patients indicated that important stenosis was present if the systolic murmur was accompanied by a thrill and associated with an increased left ventricular impulse, decreased brachial artery pulse pressure, or left ventricular hypertrophy on the electrocardiogram. The site of obstruction could not be established with certainty by clinical examination, but an early systolic ejection click was strong evidence against subvalvular stenosis.
D000293:Adolescent; D001024:Aortic Valve Stenosis; D001775:Blood Circulation; D001794:Blood Pressure; D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D003643:Death; D003645:Death, Sudden; D004562:Electrocardiography; D005260:Female; D006326:Heart Auscultation; D006330:Heart Defects, Congenital; D006331:Heart Diseases; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male
ADOLESCENCE; AORTIC VALVE STENOSIS; BLOOD CIRCULATION; CHILD; DEATH, SUDDEN; ELECTROCARDIOGRAPHY; HEART AUSCULTATION; HEART CATHETERIZATION; HEART DEFECTS, CONGENITAL; INFANT; INFANT, NEWBORN