title: 5-HYDROXYTRYPTOPHAN DECARBOXYLASE IN RAT BRAIN: EFFECT OF HYPOTHALAMIC LESIONS.
abstract: Section of the medial forebrain bundle within the lateral hypothalamus of the rat reduces the serotonin content and the 5-hydroxytryptophan decarboxylase activity in the brain. The integrity of this fiber tract appears necessary for the maintenance of normal concentrations of the amine and enzyme in the telencephalon.
mesh_terms: D006916:5-Hydroxytryptophan; D000588:Amines; D001142:Aromatic-L-Amino-Acid Decarboxylases; D001921:Brain / Q000201:enzymology*; D002262:Carboxy-Lyases; D007031:Hypothalamus; D010827:Physiology; D051381:Rats; D012106:Research; D012701:Serotonin; D013687:Telencephalon
chemical_list: D000588:Amines; D012701:Serotonin; D006916:5-Hydroxytryptophan; D002262:Carboxy-Lyases; D001142:Aromatic-L-Amino-Acid Decarboxylases
keywords: BRAIN ENZYMOLOGY; CARBOXY-LYASES; EXPERIMENTAL LAB STUDY; HYDROXYTRYPTOPHAN; HYPOTHALAMUS; PHYSIOLOGY; RATS; SEROTONIN