SOME PHYSIOLOGICAL CHARACTERISTICS OF NEOMYCIN AND KANAMYCIN-RESISTANT STRAINS OF STAPHYLOCOCCUS AUREUS.
Five hundred and fifty-two strains of Staphylococcus aureus of hospital origin were resistant to penicillin, streptomycin, and tetracycline. Of these, 298 were also resistant to neomycin and kanamycin, and this resistance was related to pigment production on glycerol monoacetate agar, the production of beta-lysin, the absence of fibrinolytic and proteolytic activity, and to phage susceptibility. The use of physiological markers, the inadequacy of phage typing, and the possible reasons for the emergence of neomycin-resistant staphylococci are discussed.
D000900:Anti-Bacterial Agents; D001431:Bacteriological Techniques; D001434:Bacteriophage Typing; D003470:Culture Media; D004352:Drug Resistance, Microbial; D005342:Fibrinolysis; D006460:Hemolysin Proteins; D007612:Kanamycin; D009355:Neomycin; D010406:Penicillins; D010860:Pigments, Biological; D012106:Research; D013203:Staphylococcal Infections; D013210:Staphylococcus; D013211:Staphylococcus aureus; D013307:Streptomycin; D013752:Tetracycline
D000900:Anti-Bacterial Agents; D003470:Culture Media; D006460:Hemolysin Proteins; D010406:Penicillins; D010860:Pigments, Biological; D007612:Kanamycin; D013752:Tetracycline; D009355:Neomycin; D013307:Streptomycin
BACTERIOLOGICAL TECHNICS; BACTERIOPHAGE TYPING; CULTURE MEDIA; DRUG RESISTANCE, MICROBIAL; EXPERIMENTAL LAB STUDY; FIBRINOLYSIS; HEMOLYSINS; KANAMYCIN; NEOMYCIN; PENICILLIN; PIGMENTS; STAPHYLOCOCCUS; STREPTOMYCIN; TETRACYCLINE