title: IONIZING RADIATION: EFFECT OF IRRADIATED MEDIUM ON SYNTHETIC PROCESSES.
abstract: The incorporation of uracil-C(14) into macromolecules in Escherichia coli cells is decreased by doses of ionizing radiation when the cells are in very dilute suspension. The decrease results from an action of irradiated medium on the cells, and a similar reaction is observed during the incorporation of thymine (indication of DNA synthesis) and of proline and valine (indicative of protein synthesis). Irradiated medium reduces the formation of beta-galactosidase but does not cause the degradation of DNA.
mesh_terms: D002247:Carbon Isotopes; D004247:DNA; D004269:DNA, Bacterial; D004926:Escherichia coli; D005696:Galactosidases; D046911:Macromolecular Substances; D008660:Metabolism; D011392:Proline; D011506:Proteins / Q000378:metabolism*; D011830:Radiation Effects; D011839:Radiation, Ionizing; D011874:Radiometry; D012106:Research; D013941:Thymine; D014498:Uracil; D014633:Valine; D001616:beta-Galactosidase
chemical_list: D002247:Carbon Isotopes; D004269:DNA, Bacterial; D046911:Macromolecular Substances; D011506:Proteins; D014498:Uracil; D004247:DNA; D011392:Proline; D005696:Galactosidases; D001616:beta-Galactosidase; D014633:Valine; D013941:Thymine
keywords: CARBON ISOTOPES; DNA, BACTERIAL; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; GALACTOSIDASE; MACROMOLECULAR SYSTEMS; METABOLISM; PROLINE; PROTEIN METABOLISM; RADIATION EFFECTS; RADIOMETRY; THYMINE; URACIL; VALINE