GENETIC MODIFICATION OF THE STRUCTURE AND AMOUNT OF DIHYDROFOLATE REDUCTASE IN AMETHOPTERIN-RESISTANT DIPLOCOCCUS PNEUMONIAE.
D004352:Drug Resistance, Microbial; D005492:Folic Acid; D006358:Hot Temperature; D008727:Methotrexate; D008967:Molecular Biology; D009154:Mutation; D010088:Oxidoreductases; D012106:Research; D013296:Streptococcus pneumoniae; D013762:Tetrahydrofolate Dehydrogenase
D005492:Folic Acid; D010088:Oxidoreductases; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate
DIPLOCOCCUS PNEUMONIAE; DRUG RESISTANCE, MICROBIAL; EXPERIMENTAL LAB STUDY; FOLIC ACID; GENETICS, BIOCHEMICAL; HEAT; METHOTREXATE; MUTATION; OXIDOREDUCTASES