A NEW LOTION FOR THE TREATMENT OF ACNE VULGARIS.
A therapeutic assessment of a new lotion containing methylprednisolone, neomycin, colloidal sulfur and aluminum chlorhydroxide complex (Neo-Medrol Acne Lotion) was carried out on 187 patients suffering from acne vulgaris.Of the 187 patients, 165 showed excellent or good response. Following enthusiastic acceptance of the lotion by the patients in the initial study, a second random study with an additional 134 subjects was undertaken to compare the active lotion with the lotion base alone.The active lotion was superior to the placebo lotion in this study, at a statistically significant level. The overall findings suggest that this lotion is an efficient preparation for the control of acne vulgaris (early and late types) and it also showed promise in the treatment of a few cases of acne rosacea and seborrheic dermatitis facialis.
D000152:Acne Vulgaris; D000535:Aluminum; D035843:Biomedical Research; D002724:Chlorobutanol; D012628:Dermatitis, Seborrheic; D004338:Drug Combinations; D004358:Drug Therapy; D004655:Emulsions; D006801:Humans; D008775:Methylprednisolone; D009355:Neomycin; D010919:Placebos; D012393:Rosacea; D013455:Sulfur
D004338:Drug Combinations; D004655:Emulsions; D010919:Placebos; D013455:Sulfur; C005766:chlorobutanol, methylprednisolone, neomycin drug combination; D000535:Aluminum; D002724:Chlorobutanol; D009355:Neomycin; D008775:Methylprednisolone
ACNE; ALUMINUM; CLINICAL RESEARCH; DRUG THERAPY; METHYLPREDNISOLONE; NEOMYCIN; PLACEBOS; ROSACEA; SEBORRHEA; SULFUR