title: ANAPHYLACTIC REACTION OF DENERVATED SKELETAL MUSCLE IN THE GUINEA PIG.
abstract: Muscle strips taken from chronically denervated hemidiaphragms of guinea pigs immunized to ovalbumin react in vitro to the administration of small amounts of this protein with a contraction similar to that of visceral muscle in the Schultz-Dale reaction. A sustained shortening is produced by histamine on denervated diaphragmatic muscle from both sensitized and nonsensitized guinea pigs.
mesh_terms: D000009:Abdominal Muscles; D000109:Acetylcholine; D000707:Anaphylaxis; D000818:Animals; D003714:Denervation; D003964:Diaphragm; D006168:Guinea Pigs; D006632:Histamine; D007114:Immunization; D009121:Muscle Denervation; D018482:Muscle, Skeletal; D009132:Muscles; D010047:Ovalbumin; D010600:Pharmacology; D012106:Research; D012709:Serum Albumin
chemical_list: D012709:Serum Albumin; D006632:Histamine; D010047:Ovalbumin; D000109:Acetylcholine
keywords: ACETYLCHOLINE; ANAPHYLAXIS; DENERVATION; DIAPHRAGM; EXPERIMENTAL LAB STUDY; GUINEA PIGS; MUSCLES; OVALBUMIN; PHARMACOLOGY; SERUM ALBUMIN