MOLONEY VIRUS-INDUCED LEUKEMIAS OF MICE: MEASUREMENT IN VITRO OF SPECIFIC ANTIGEN.
A modified test for cytotoxic antibody may be used to measure antibody directed against the tumor-specific antigen of leukemias of mice induced by Moloney virus; cell death is detected by liberation of (51)Cr. An inhibition test based on this technique permits accurate measurement of tumor-specific antigen in cells and subcellular fractions.
D000818:Animals; D000906:Antibodies; D000941:Antigens; D000951:Antigens, Neoplasm; D002859:Chromium Isotopes; D066298:In Vitro Techniques; D007938:Leukemia; D009052:Leukemia Virus, Murine; D007942:Leukemia, Experimental; D051379:Mice; D008979:Moloney murine leukemia virus; D009858:Oncogenic Viruses; D012106:Research
D000906:Antibodies; D000941:Antigens; D000951:Antigens, Neoplasm; D002859:Chromium Isotopes
ANTIGENS; CHROMIUM ISOTOPES; EXPERIMENTAL LAB STUDY; LEUKEMIA, EXPERIMENTAL; MICE; ONCOGENIC VIRUSES