title: POLYPEPTIDE CHAINS OF ANTIBODY: EFFECTIVE BINDING SITES REQUIRE SPECIFICITY IN COMBINATION.
abstract: Separated chains from antibody of different rabbits do not always give effective binding sites although combination of the chains does occur. There is a specificity of combination such that only chains from the same (or perhaps a related) rabbit form effective binding sites. There appears to be preferential combination between those chains which yield effective sites.
mesh_terms: D000818:Animals; D000906:Antibodies; D001665:Binding Sites; D006241:Haptens; D007136:Immunoglobulins; D010455:Peptides; D011817:Rabbits; D012106:Research; D014461:Ultracentrifugation
chemical_list: D000906:Antibodies; D006241:Haptens; D007136:Immunoglobulins; D010455:Peptides
keywords: ANTIBODIES; EXPERIMENTAL LAB STUDY; HAPTENS; PEPTIDES; RABBITS; ULTRACENTRIFUGATION