SPECIFICITY OF MACROGLOBULIN ANTIBODY SYNTHESIZED BY THE NORMAL HUMAN FETUS.
The umbilical cord blood of 47 out of 54 normal human infants contains hemagglutinating activity directed toward cells coated with a type-L Bence-Jones protein. This hemagglutinating material, in some instances, is present in cord blood in the absence of such activity in the maternal blood. Ultracentrifugation of cord serum in a sucrose gradient shows that the activity is associated with the macroglobulin fractions.
D000906:Antibodies; D000917:Antibody Formation; D001536:Bence Jones Protein; D005260:Female; D005312:Fetal Blood; D005333:Fetus; D006384:Hemagglutination; D006386:Hemagglutination Tests; D006801:Humans; D008259:Macroglobulins; D010827:Physiology; D011247:Pregnancy; D014461:Ultracentrifugation; D014470:Umbilical Cord
D000906:Antibodies; D008259:Macroglobulins; D001536:Bence Jones Protein
ANTIBODY FORMATION; BENCE JONES PROTEIN; FETUS; HEMAGGLUTINATION; MACROGLOBULINS; PHYSIOLOGY; PREGNANCY; ULTRACENTRIFUGATION; UMBILICAL CORD