ERYTHROPOIESIS AND RENAL HOMOTRANSPLANTATION.
Following the successful replacement of diseased kidneys by renal homotransplants, regression of the anemia of chronic renal disease was found in five patients. Increased erythropoietic-stimulating activity was demonstrated in the serum of one patient seven weeks after renal transplantation when he suffered a severe hemorrhage. It is postulated that a renal homotransplant can produce enough erythropoietin to maintain a normal hemoglobin value and to respond to the stimulus of a sudden hemorrhage.
D000740:Anemia; D000068817:Epoetin Alfa; D004906:Erythrocyte Count; D004920:Erythropoiesis; D004921:Erythropoietin; D006454:Hemoglobins; D006470:Hemorrhage; D006801:Humans; D007674:Kidney Diseases; D007676:Kidney Failure, Chronic; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications; D012156:Reticulocytes; D014184:Transplantation, Homologous
D006454:Hemoglobins; D004921:Erythropoietin; D000068817:Epoetin Alfa
ANEMIA; ERYTHROCYTE COUNT; ERYTHROPOIESIS; HEMORRHAGE; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; RETICULOCYTES; TRANSPLANTATION, HOMOLOGOUS