TENSION GRADIENTS ACCOMPANYING ACCELERATED OXYGEN TRANSPORT IN A MEMBRANE.
Facilitated transport of oxygen through hemoglobin has been studied by use of a membrane sandwich of hemoglobin, Teflon, and water. Transport is enhanced only when there is a hemoglobin-bound-0(2) gradient in the pigment. When passing through a fully oxygenated layer, the accelerated transport is carried by an increased diffusion gradient of oxygen pressure through the solvent. The results substantiate experimentally the diffusion gradients proposed by Zilversmit.
D001669:Biochemical Phenomena; D001671:Biochemistry; D001692:Biological Transport; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005374:Filtration; D005465:Fluorocarbon Polymers; D006454:Hemoglobins; D010100:Oxygen; D011312:Pressure; D012106:Research; D012996:Solutions
D005465:Fluorocarbon Polymers; D006454:Hemoglobins; D012996:Solutions; D010100:Oxygen
BIOCHEMISTRY; BIOLOGICAL TRANSPORT; CHEMISTRY, PHYSICAL; EXPERIMENTAL LAB STUDY; FILTRATION; FLUOROCARBON POLYMERS; HEMOGLOBIN; OXYGEN; SOLUTIONS