OXYGEN-HEMOGLOBIN SYSTEM: A MODEL FOR FACILITATED MEMBRANOUS TRANSPORT.
Enhanced transport of oxygen in a Millipore filter containing a solution of hemoglobin can be accounted for by the diffusion of free oxygen as well as of hemoglobin-bound oxygen. A model shows that, at oxygen tensions at which the hemoglobin is fully saturated in a portion of the membrane, the enhanced transport is due to a steeper gradient for free oxygen, whereas in the rest of the membrane an "(oxy)hemoglobin shuttle" operates. A similar model may be useful for explaining facilitated diffusion in other systems.
D001669:Biochemical Phenomena; D001671:Biochemistry; D001692:Biological Transport; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004058:Diffusion; D055459:Facilitated Diffusion; D005374:Filtration; D006454:Hemoglobins; D008433:Mathematics; D008962:Models, Theoretical; D010100:Oxygen; D012106:Research; D012996:Solutions
D006454:Hemoglobins; D012996:Solutions; D010100:Oxygen
BIOCHEMISTRY; BIOLOGICAL TRANSPORT; CHEMISTRY, PHYSICAL; EXPERIMENTAL LAB STUDY; FILTRATION; HEMOGLOBIN; MATHEMATICS; MODELS, THEORETICAL; OXYGEN; SOLUTIONS