SEROLOGICAL SURVEY OF CHILDREN IN MOSCOW FOR ANTIBODY TO POLIOVIRUSES, 1961 AND 1962.
In 1961 and 1962, 2-3 years after mass-vaccination campaigns with live Sabin poliovirus, mass serological surveys for poliovirus antibodies in the child population of Moscow were carried out. A total of 605 and 769 children aged from 6 months to 15 years were examined in autumn 1961 and autumn 1962, respectively. The results showed that neutralizing antibodies had been produced in 97-100% of the children vaccinated, but that there appeared to be some deficiency in antibody response in children under 2 years of age. Precipitating and complement-fixing antibodies were found in a considerable proportion of normal children after revaccination, indicating the occurrence of fresh infection. This was considered a manifestation of insufficient resistance of the alimentary tract, and suggests that the possibility of such reactions occurring after revaccination should be taken into account in the serodiagnosis of poliomyelitis and similar diseases.
D000293:Adolescent; D000906:Antibodies; D000914:Antibodies, Viral; D000917:Antibody Formation; D002648:Child; D006801:Humans; D007223:Infant; D032541:Mass Vaccination; D009031:Moscow; D011051:Poliomyelitis; D017955:Poliovirus; D011055:Poliovirus Vaccine, Oral; D023321:Poliovirus Vaccines; D012621:Seasons; D013223:Statistics as Topic; D014586:USSR
D000906:Antibodies; D000914:Antibodies, Viral; D011055:Poliovirus Vaccine, Oral; D023321:Poliovirus Vaccines
ADOLESCENCE; ANTIBODY FORMATION; CHILD; INFANT; POLIOVIRUS VACCINE, ORAL; STATISTICS; USSR