RENIN PRODUCTION BY ORGAN CULTURES OF RENAL CORTEX.
Diploid cells of the human and canine renal cortex can be isolated by newly developed techniques for organ culture. Some of these cells have abundant Bowie's positive granules. Bioassays for renin activity have shown that these granular cells can synthesize considerable amounts of renin in vitro. These investigations provide a model for studying the production of renin at cellular level.
D000818:Animals; D001669:Biochemical Phenomena; D001671:Biochemistry; D001681:Biological Assay; D004285:Dogs; D006801:Humans; D007668:Kidney; D009924:Organ Culture Techniques; D012083:Renin; D012106:Research; D012107:Research Design; D046509:Tissue Culture Techniques
D012083:Renin
BIOCHEMISTRY; DOGS; KIDNEY; RENIN; TISSUE CULTURE