Tissue culture of human skin and chick spleen as a method for evaluating the primary irritant producing capacity of topical medicaments; correlation of results with clinical observations.
D000818:Animals; D002645:Chickens; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007509:Irritants; D012867:Skin; D013154:Spleen; D046509:Tissue Culture Techniques
D007509:Irritants
DRUGS/toxicity; SKIN; SPLEEN; TISSUE CULTURE