Investigation of tumor variants recovered from mice with systemic leukemia (L1210) after extensive therapy with 3',5'-dichloroamethopterin and 3'-bromo-5'-chloroamethopterin.
D000818:Animals; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D007938:Leukemia; D007942:Leukemia, Experimental; D008727:Methotrexate / Q000031:analogs & derivatives; D051379:Mice
D005493:Folic Acid Antagonists; C004763:3',5'-dichloromethotrexate; D008727:Methotrexate
FOLIC ACID ANTAGONISTS/pharmacology; LEUKEMIA/experimental