Studies on the metabolism of rat ascites tumor with nitrogen mustard sensitive and resistant strains. VI. Inhibition of the in vitro incorporation of C-14-orotic acid into nucleic acids by nitrogen mustard.
D000818:Animals; D001201:Ascites; D004247:DNA / Q000378:metabolism*; D066298:In Vitro Techniques; D008466:Mechlorethamine; D009369:Neoplasms / Q000378:metabolism*; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology*; D009696:Nucleic Acids; D009963:Orotic Acid / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D051381:Rats
D009588:Nitrogen Mustard Compounds; D009696:Nucleic Acids; D008466:Mechlorethamine; D009963:Orotic Acid; D012313:RNA; D004247:DNA
DESOXYRIBONUCLEIC ACID/metabolism; NEOPLASMS/metabolism; NITROGEN MUSTARDS/pharmacology; OROTIC ACID/metabolism; RIBONUCLEIC ACID/metabolism