The effect of anticholinergic drugs on the mucus content of gastric juice.
Increasing suppression of gastric secretion by anticholinergic drugs is accompanied by a rising mucus concentration; the actual output of mucus shows little change despite a marked reduction in the secretory volume. The problems involved in the estimation of mucus secretion and the importance of the above findings in relation to the therapeutic use of anticholinergic drugs in peptic ulceration are discussed.
D001285:Atropine / Q000494:pharmacology*; D018680:Cholinergic Antagonists; D005750:Gastric Juice / Q000737:chemistry*; D006801:Humans; D009093:Mucus; D010276:Parasympatholytics / Q000494:pharmacology*; D010437:Peptic Ulcer
D018680:Cholinergic Antagonists; D010276:Parasympatholytics; D001285:Atropine
ATROPINE/pharmacology; GASTRIC JUICE/chemistry; PARASYMPATHOLYTICS/pharmacology