title: The methamphetamine burn patient.
abstract: Early aggressive fluid resuscitation has significantly decreased the morbidity and mortality associated with volume losses from large burns. Although most patients are adequately resuscitated using the Parkland formula, we noted increased fluid requirements for shock resuscitation in patients involved in methamphetamine laboratory explosions. Because predominant users are young healthy individuals in their 20s and 30s, we had not anticipated burn shock resuscitation failures in this patient group. We reviewed our experience with burn patients with documented methamphetamine use to determine whether this patient group presents new dilemmas to the burn surgeon. A 2-year retrospective study of 30 patients (15 methamphetamine users, 15 controls) revealed that the methamphetamine burn patient requires two to three times the standard Parkland formula resuscitation. In this study, methamphetamine burns larger than 40% TBSA had a 100% mortality.
mesh_terms: D000328:Adult; D001753:Blast Injuries / Q000150:complications / Q000401:mortality / Q000628:therapy*; D002053:Burn Units / Q000706:statistics & numerical data; D002056:Burns / Q000150:complications / Q000401:mortality / Q000628:therapy*; D004781:Environmental Exposure / Q000032:analysis; D005107:Explosions; D005260:Female; D005440:Fluid Therapy / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000032:analysis / Q000138:chemical synthesis; D012151:Resuscitation / Q000379:methods* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012769:Shock / Q000209:etiology / Q000517:prevention & control*; D015996:Survival Rate
chemical_list: D008694:Methamphetamine