title: Pre-donated autologous blood transfusion in scoliosis surgery.
abstract: We studied the use of autologous pre-donatedblood transfusion in surgery for scoliosis in 45 patients who were divided into two groups; 27 who pre-donated autologous blood (group 1) and 18 who were planned recipients of allogenic blood (group 2). Normovolaemic haemodilution and intra-operative blood salvage was used in six patients in group 1 and three patients in group 2. The two groups did not differ significantly with respect to age, American Society of Anaesthesiologists score, mean operative time, number of vertebral segments fused, total blood loss, length of stay in intensive care and length of stay in hospital. The risk of requiring allogenic blood transfusion was found to be significantly less in group 1 (7.4% v 88.9%, p < 0.001). Only 5.21% of autologous units were wasted. Although intra-operative blood salvage reduced the total blood loss in both groups, it did not affect the need for subsequent allogenic transfusion or reduce the number of pre-donated autologous units which were given (p < 0.67). Autologous blood transfusion requiredextra time, personnel, resources and cost pounds sterling 28.88 per patient more than allogenic transfusion, however, the projected costs at May 2002 make this programme cost-effective by pounds sterling 51.54 per patient. Pre-donated autologous blood transfusion is acceptable and safe in scoliosis surgery. It significantly reduces the subsequent requirement of allogenic transfusion. Although the cost is currently more than allogenic transfusion, with the increase in the costs of the latter and the decrease in potential donors which is anticipated, pre-donation of autologous blood will become comparatively cost-effective.
mesh_terms: D000293:Adolescent; D000328:Adult; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous / Q000191:economics / Q000379:methods*; D003362:Cost-Benefit Analysis; D033001:Directed Tissue Donation; D004739:England; D017048:Health Care Costs; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007902:Length of Stay; D008875:Middle Aged; D012189:Retrospective Studies; D012600:Scoliosis / Q000601:surgery*