title: Synthetic study of cytosaminomycins using the intramolecular glycosylation as a key step.
abstract: 2',6'-Dideoxy-beta-D-hexopyranosyl pyrimidine nucleoside, which is a component of anticoccidal antibiotics--cytosaminomycins, was synthesized in a stereoselective manner via the intramolecular pyrimidine delivery method. Further glycosylaion of the 4'-position with a glycosyl fluoride gave the disaccharide nucleoside skeleton of the cytosaminomycins.
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D002240:Carbohydrate Sequence; D006031:Glycosylation
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C089081:cytosaminomycin A; C089082:cytosaminomycin B; C089083:cytosaminomycin C; C089084:cytosaminomycin D