[Indications and modalities of assisted reproductive techniques in infertile women with cystic fibrosis].
OBJECTIVE
To treat cystic fibrosis women who failed to conceive.


METHODS
Multidisciplinary coordinated approach in 20 infertile women affected with cystic fibrosis. Advisability of pregnancy was based on the assessment of pulmonary and nutritional status, risks of maternal health deterioration, infertility factors, risk of cystic fibrosis in the offspring. Assisted reproductive techniques in moderately affected women are described.


RESULTS
Three patients requested only information, three were discouraged, two are still evaluated, 12 were treated and three delivered healthy children. The pulmonary status of each patient remained unchanged 36 months after delivery, and all three children remain healthy.


CONCLUSIONS
Assisted reproductive techniques are an option in moderately affected infertile cystic fibrosis women. Advisability and management of pregnancy should be provided by a coordinated team of healthcare professionals with knowledge and experience in cystic fibrosis.
D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy*; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted; D016896:Treatment Outcome