title: Anesthetic implications of cervicofacial necrotizing fasciitis.
abstract: Cervicofacial necrotizing fasciitis is a necrotizing soft tissue infection of face and neck spreading at the level of fascia. It has been described as a putrid ulcer, phagedaena, and hospital gangrene. It has a high mortality rate, and presents a challenge to anesthesiologists who must secure an airway to deliver anesthesia safely. We report a case of cervicofacial necrotizing fasciitis in which the patient underwent repeated radical surgical debridement of face and neck, including a mandibulectomy. These critically ill patients often present with sepsis and multiple system organ failure. Extensive preoperative evaluation, invasive monitoring, and possibly the use of vasopressors and inotropes are essential in treating these patients. The tracheas of these patients should remain intubated after initial debridement. Tracheostomy should be performed early. Antibiotic therapy, nutritional support, early debridement, and hyperbaric oxygen therapy all help to decrease mortality in these patients.
mesh_terms: D000769:Anesthesia, Inhalation; D003646:Debridement; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005145:Face / Q000473:pathology / Q000601:surgery*; D019115:Fasciitis, Necrotizing / Q000473:pathology / Q000601:surgery*; D017809:Fatal Outcome; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008334:Mandible / Q000601:surgery; D008875:Middle Aged; D009333:Neck / Q000473:pathology / Q000601:surgery*