Changes in the expression of tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), galanin (GAL), vasoactive intestinal polypeptide (VIP) and substance P (SP) in the uterine cervix-projecting neurons located in the lumbar paravertebral ganglia of the pig.
The uterine cervix-projecting neurons located in the lumbar paravertebral ganglia were identified by retrograde tracing. These contained immunoreactivity to TH and DBH. No immunoreactivity to GAL, VIP and SP was found in the neurons. Extirpation of the uterus reduced the expression of TH and induced the expression of GAL in the neurons. Expression of other substances studied was unchanged.
D000818:Animals; D019771:Axotomy; D002584:Cervix Uteri / Q000294:innervation; D004299:Dopamine beta-Hydroxylase / Q000378:metabolism*; D015536:Down-Regulation / Q000502:physiology; D005260:Female; D005455:Fluorescent Antibody Technique; D019004:Galanin / Q000378:metabolism; D005728:Ganglia, Sympathetic / Q000166:cytology / Q000378:metabolism*; D007001:Hypogastric Plexus / Q000166:cytology / Q000378:metabolism; D007044:Hysterectomy; D008159:Lumbar Vertebrae; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*; D034421:Sus scrofa; D017779:Sympathetic Fibers, Postganglionic / Q000166:cytology / Q000378:metabolism; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*; D015854:Up-Regulation / Q000502:physiology; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D019004:Galanin; D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase