Microbiologic characteristics, serologic responses, and clinical manifestations in severe acute respiratory syndrome, Taiwan.
The genome of one Taiwanese severe acute respiratory syndrome-associated coronavirus (SARS-CoV) strain (TW1) was 29,729 nt in length. Viral RNA may persist for some time in patients who seroconvert, and some patients may lack an antibody response (immunoglobulin G) to SARS-CoV <21 days after illness onset. An upsurge of antibody response was associated with the aggravation of respiratory failure.
D000328:Adult; D000914:Antibodies, Viral / Q000302:isolation & purification; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology*; D005260:Female; D016679:Genome, Viral; D006801:Humans; D008297:Male; D008875:Middle Aged; D020133:Reverse Transcriptase Polymerase Chain Reaction; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology*; D013624:Taiwan / Q000453:epidemiology
D000914:Antibodies, Viral