title: Detection of antibodies to Brucella abortus in animal handlers.
abstract: 1. Our study showed a prevalence of 5.33% in animal handlers working in an urban city like Pune. The prevalence would definitely be higher in a population from a rural area. 2. All these cases who showed presence of antibodies to B. abortus, had varied clinical manifestations, characteristic of the protean manifestations in brucellosis. Likewise in our study we had cases ranging from arthritis, abortions and genito urinary manifestations. 3. All the antibody positive cases had significant antibody titres. The clinicians miss many cases of brucellosis because it is not considered as an alternative diagnosis. The clinician should keep in mind the possibility of an occupational or environmental exposure in cases of P.U.O. It would also be worthwhile to create awareness of the disease in such professions so that necessary precautions and periodic screening of such occupationally exposed people can be done. Studies are needed to assess the role of brucellosis as a cause of morbidity in India, which had not received the attention it deserved. Prevention of human brucellosis focuses mainly on elimination of infection in cattle along with hygiene, vaccine, and effective heating and pasteurization of dairy products and related foods.
mesh_terms: D000822:Animal Husbandry; D000907:Antibodies, Bacterial / Q000097:blood* / Q000276:immunology*; D002003:Brucella abortus / Q000276:immunology*; D002006:Brucellosis / Q000097:blood* / Q000453:epidemiology / Q000276:immunology*; D003612:Dairying; D006801:Humans; D007194:India / Q000453:epidemiology; D009784:Occupational Diseases / Q000097:blood* / Q000453:epidemiology / Q000276:immunology*; D014730:Veterinary Medicine
chemical_list: D000907:Antibodies, Bacterial