[The relationship between proto-oncogene and testicular function].
Proto-oncogene, the fundamental component of cellular genome, is rarely or finitely expressed in normal conditions, and can regulate cellular proliferation, differentiation and information conduction. Many proto-oncogenes show the temporal and specific expression during spermatogenesis. The expression of some proto-oncogenes reinforces in the growth and development of Sertoli cells and Leydig cells. To explore the relationship between proto-oncogene and testicular function and that between proto-oncogene and regulative factors of testicular function helps to comprehend the regulation of the testicular function at the molecular level.
D000818:Animals; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D007985:Leydig Cells / Q000166:cytology; D008297:Male; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes / Q000502:physiology*; D012708:Sertoli Cells / Q000166:cytology; D013091:Spermatogenesis / Q000235:genetics*; D013737:Testis / Q000502:physiology*