Deletion (6)(p22p25) is a recurrent anomaly of thymoma: report of a second case and review of the literature.
A patient with type AB thymoma and del(6)(p22p25) as the sole cytogenetic anomaly is described. This is the second report of a del(6)(p22p25) in a thymoma. The same deletion was previously found in association with a type A thymoma. Both patients presented with benign tumors. These data suggest that partial deletion of the short arm of chromosome 6 is a nonrandom change associated with benign thymomas.
D002896:Chromosomes, Human, Pair 6; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D017384:Sequence Deletion; D013945:Thymoma / Q000235:genetics* / Q000473:pathology; D013953:Thymus Neoplasms / Q000235:genetics* / Q000473:pathology