title: [Vacuum sealing of extensive wound healing disorders after kidney transplantation].
abstract: With the introduction of mycophenolate mofetil (MMF) in renal transplantation, acute rejection episodes diminished and short-term graft survival improved. Better graft outcome, however, is followed by several surgical complications attributed to MMF. Patients with risk factors (adiposity, diabetes mellitus, advanced age) show an increased rate of healing by second intention. We treated two patients with the vacuum sealing technique so that after 15 days a secondary suture became possible in each case. To date the vacuum sealing technique has been used mainly in traumatology, abdominal surgery, surgery for acute infections of soft tissue and bone, and problem wounds with reduced wound-healing capacity (chronic leg ulcer). This article presents two cases of successful application of the vacuum sealing technique in renal transplantation after prolonged wound healing.
mesh_terms: D015992:Body Mass Index; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016030:Kidney Transplantation; D009173:Mycophenolic Acid / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009779:Occlusive Dressings; D011140:Polyurethanes; D011183:Postoperative Complications / Q000628:therapy*; D012307:Risk Factors; D013396:Suction / Q000295:instrumentation*; D013528:Surgical Staplers; D013529:Surgical Wound Dehiscence / Q000628:therapy*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D007166:Immunosuppressive Agents; C027324:Opsiture; D011140:Polyurethanes; D009173:Mycophenolic Acid