Racial difference between white and black Zimbabweans in the haemolytic activity of A, B, O antibodies.
Race is thought to be one of the factors determining the level of ABO antibodies. The objective of this study was to compare the haemolytic activity of anti-A and anti-B in two racial groups, Black and White Zimbabweans, living under similar conditions. Serum haemolytic activity was assessed by comparing spectrophotometrically, released haemoglobin when known A1 and B red cells were incubated in equal volumes of subjects' serum and water. Serum from Black subjects showed greater haemolytic activity of anti-A and anti-B than serum from White subjects. Within each racial group, anti-B showed greater haemolytic activity than anti-A. Race may be an important factor in the haemolytic activity of ABO antibodies.
D000017:ABO Blood-Group System / Q000097:blood / Q000235:genetics* / Q000276:immunology*; D000328:Adult; D000906:Antibodies / Q000097:blood / Q000235:genetics* / Q000276:immunology*; D044383:Black People / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006402:Hematologic Diseases / Q000097:blood / Q000235:genetics* / Q000276:immunology*; D006461:Hemolysis / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013053:Spectrophotometry; D044465:White People / Q000235:genetics*; D015030:Zimbabwe
D000017:ABO Blood-Group System; D000906:Antibodies