title: Four-component reactions for a new diastereoselective synthesis of chiral quaternary centers.
abstract: The one-pot preparation of chiral homoallylic alcohol and amine derivatives was easily achieved by carbocupration of alkynyl sulfoxides followed by an in situ zinc homologation and reaction with aldehydes or imines. In this process, three new carbon-carbon bonds were created as well as quaternary and tertiary chiral centers with excellent diastereo- and enantioselectivities.