title: Epidural hematoma associated with dextran infusion.
abstract: The authors describe a case of epidural hematoma in association with dextran infusion in a patient who had undergone a peripheral vascular operation with epidural analgesia. Possible mechanisms for the anticoagulant effect of dextran and guidelines for the use of anticoagulant therapy in patients undergoing epidural anesthesia are discussed.
mesh_terms: D000368:Aged; D000767:Anesthesia, Epidural / Q000009:adverse effects* / Q000379:methods; D000768:Anesthesia, General / Q000379:methods; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D019299:Decompression, Surgical; D003911:Dextrans / Q000008:administration & dosage / Q000009:adverse effects*; D004322:Drainage; D016903:Drug Monitoring; D004630:Emergencies; D005260:Female; D006083:Graft Occlusion, Vascular / Q000517:prevention & control; D006407:Hematoma, Epidural, Cranial / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007262:Infusions, Intravenous; D007383:Intermittent Claudication / Q000601:surgery; D007796:Laminectomy; D017116:Low Back Pain / Q000139:chemically induced; D008279:Magnetic Resonance Imaging; D016491:Peripheral Vascular Diseases / Q000601:surgery; D013117:Spinal Cord Compression / Q000139:chemically induced; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants; D003911:Dextrans