Left temporoparietal transcranial magnetic stimulation in treatment-resistant schizophrenia with verbal hallucinations.
Left temporoparietal repetitive transcranial magnetic stimulation (rTMS) reportedly diminishes verbal hallucinations. A 21-year-old schizophrenic man, who had killed his mother in the belief that she was a demon, failed to respond to combined treatment with a variety of antipsychotic agents. His persistent hallucinations consisted of two voices (God and the Devil). As an adjunct to continued antipsychotic medication, the patient received a course of rTMS: 10 sessions of 1-Hz stimulations near Wernicke's area. After rTMS, the patient's hallucinations grew less intrusive and he no longer required isolation. Although the improvement could be a delayed effect of medication, further trials of rTMS in cases of this type appear justified.
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004292:Dominance, Cerebral / Q000502:physiology*; D006212:Hallucinations / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D006708:Homicide / Q000523:psychology; D006801:Humans; D008297:Male; D010296:Parietal Lobe / Q000503:physiopathology*; D012563:Schizophrenia, Paranoid / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D013702:Temporal Lobe / Q000503:physiopathology*; D050781:Transcranial Magnetic Stimulation / Q000627:therapeutic use*; D016896:Treatment Outcome
D014150:Antipsychotic Agents