title: [Neuroleptic therapy of comorbid narcotic dependent patients in ambulatory methadone maintenance].
abstract: Methadon maintenance therapy with opiate addicts who suffer from a comorbid schizophrenia in an outpatient treatment setting of a psychiatric hospital is described. We examined five patients looking for periods of inpatient treatment, drug free urine tests, social integration and illegal activities before and after neuroleptic treatment. In comparison with standard neuroleptics patients show under the therapy with atypical neuroleptics better outcome in drug urine tests especially concerning cannabis and benzodiazepines. According to these findings, the best improvements seem to occur with a combination of methadone and clozapine.
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003024:Clozapine / Q000627:therapeutic use*; D015897:Comorbidity; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006556:Heroin Dependence / Q000453:epidemiology / Q000534:rehabilitation*; D006778:Hospitals, Psychiatric; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D010044:Outpatient Clinics, Hospital; D010359:Patient Readmission / Q000706:statistics & numerical data; D012559:Schizophrenia / Q000453:epidemiology / Q000534:rehabilitation*; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D008691:Methadone