title: Increase in corneal asphericity after standard laser in situ keratomileusis for myopia is not inherent to the Munnerlyn algorithm.
abstract: OBJECTIVE
  Standard refractive surgery for myopia induces a shift in corneal asphericity toward positive values, resulting in an increase of spherical aberration. Analytical studies of changes in theoretical corneal shape after application of standard algorithms have yielded controversial conclusions. This study tries to resolve this controversy and discusses causes of optical degradation after refractive surgery.
  
  
  METHODS
  Computationally, we subtracted from real preoperative corneas the ablation depth given by the Munnerlyn equation and the parabolic approximation of the Munnerlyn equation. We compared the predicted postoperative corneal asphericity (and corneal spherical aberration) with real postoperative corneal asphericities of the same eyes, after laser in situ keratomileusis (LASIK).
  
  
  RESULTS
  Corneal asphericity increased after LASIK in real eyes, with an increase proportional to the amount of correction. This increase was not predicted by the computational application of the Munnerlyn algorithm, which predicted a slight decrease of corneal asphericity. The parabolic approximation of the Munnerlyn algorithm produced an increase in corneal asphericity that correlated with the amount of correction, but was less than the clinical findings.
  
  
  CONCLUSIONS
  Potential causes for increased asphericity (radial changes in laser efficiency, epithelial healing, and biomechanical response) are discussed. These conclusions are important for the design of optimized and customized ablation algorithms, since the theoretical performance of a given ablation algorithm (ie, Munnerlyn algorithm) can differ drastically from real outcomes.
mesh_terms: D000328:Adult; D000465:Algorithms; D003315:Cornea / Q000473:pathology*; D019781:Corneal Topography; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D009216:Myopia / Q000601:surgery*; D011184:Postoperative Period