Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: optimizing for cyclization-trapping over cycloisomerization.
[reaction: see text] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D006844:Hydrocarbons, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D007536:Isomerism; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010797:Phthalimides / Q000737:chemistry
D000475:Alkenes; D006844:Hydrocarbons, Cyclic; D007202:Indicators and Reagents; D010797:Phthalimides; D010165:Palladium; C037437:N-hydroxyphthalimide