Metastasis of renal cell carcinoma to haemangioblastoma of the spinal cord in von Hippel-Lindau disease: case report and review of the literature.
A case is presented demonstrating the unusual phenomenon of a renal cell carcinoma metastasising to a spinal haemangioblastoma in a patient with von Hippel-Lindau (VHL) disease. Recent advances in the molecular biology of VHL disease relevant to possible mechanisms of tumour-to-tumour metastasis are briefly reviewed.
D000328:Adult; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D018325:Hemangioblastoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D018396:Mucin-1 / Q000378:metabolism; D009378:Neoplasms, Multiple Primary / Q000378:metabolism / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D016896:Treatment Outcome; D006623:von Hippel-Lindau Disease / Q000150:complications / Q000378:metabolism / Q000473:pathology*
D001457:Anion Exchange Protein 1, Erythrocyte; D014408:Biomarkers, Tumor; D018396:Mucin-1