title: Three cases of cochleosaccular endolymphatic hydrops without vertigo revealed by furosemide-loading vestibular evoked myogenic potential test.
abstract: OBJECTIVE
  To describe possible cases of cochleosaccular endolymphatic hydrops without vertigo.
  
  
  METHODS
  Retrospective case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Three patients with possible cochleosaccular hydrops without vertigo were studied. The basis of diagnosis was positive result of the furosemide-loading vestibular evoked myogenic potential test, no canal paresis in the caloric test, and recurrent cochlear symptoms or fluctuating low-tone hearing loss.
  
  
  METHODS
  In case 1, a 47-year-old woman had recurrent left aural fullness and tinnitus and a few weeks later complained of a floating sensation and could not stand up. The furosemide-loading vestibular evoked myogenic potential test showed a positive result in the left ear. In case 2, a 24-year-old woman complained of a backward falling sensation lasting several seconds; subsequently, a severe floating sensation persisted and she could not stand up for several days. Audiography showed fluctuating low-tone hearing loss in the left ear, and the furosemide-loading vestibular evoked myogenic potential test showed a positive result. In case 3, a 41-year-old woman had a floating sensation while walking and subsequently complained of tinnitus in the left ear. She could not stand up because of a severe floating sensation and, moreover, complained of a sudden falling sensation lasting for several seconds. The furosemide-loading vestibular evoked myogenic potential test indicated a positive result in the left ear.
  
  
  CONCLUSIONS
  The patients in cases 2 and 3 complained of a short-lasting sensation of falling down. Severe disequilibrium that prohibited standing up was noted in all cases. It was suggested that these symptoms were caused by saccular hydrops.
mesh_terms: D000328:Adult; D003051:Cochlea / Q000503:physiopathology*; D018159:Endolymphatic Hydrops / Q000175:diagnosis* / Q000503:physiopathology; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D005260:Female; D005665:Furosemide; D006801:Humans; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012189:Retrospective Studies; D012444:Saccule and Utricle / Q000503:physiopathology*; D014724:Vestibular Function Tests; D014725:Vestibular Nerve / Q000187:drug effects / Q000503:physiopathology
chemical_list: D005665:Furosemide