[Quantitative determination of cell composition of human granulation tissue by fluorescence activated cell sorting (FAC)].
Granulation tissue of normal and non-healing human wounds showed a similar distribution pattern of the cell populations investigated by FACS analysis, whereas only non-healing wounds revealed a reduced density of cells and intercellular matrix. Thus, supporting the thesis that impaired wound healing is not caused by changes of the cellular distribution pattern of granulation tissue, but possibly by lessened cell function.
D002452:Cell Count; D005109:Extracellular Matrix / Q000473:pathology; D005434:Flow Cytometry; D006097:Granulation Tissue / Q000473:pathology*; D006801:Humans; D014945:Wound Healing / Q000502:physiology*