title: [Clinical observation on treatment of vitiligo with xiaobai mixture].
abstract: OBJECTIVE
  To observe the therapeutic effect of Xiaobai Mixture (XBM) in treating vitiligo.
  
  
  METHODS
  Seventy-four patients with vitiligo were randomly divided into the XBM group treated with XBM and the control group treated with 8-MOP. The therapeutic effect, nail-fold microcirculation, plasma endothelin-1, serum immunoglobulin were observed and compared.
  
  
  RESULTS
  The therapeutic effect of XBM was better than that of 8-MOP (P < 0.05). XBM could also obviously improve the nail-fold microcirculation, elevate the plasma endothelin-1 level and lower the serum IgG (P < 0.01).
  
  
  CONCLUSIONS
  XBM has superiority in treating vitiligo.
mesh_terms: D000293:Adolescent; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D019332:Endothelin-1 / Q000097:blood; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009262:Nails / Q000098:blood supply; D008517:Phytotherapy; D014820:Vitiligo / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal; D019332:Endothelin-1; D007074:Immunoglobulin G