Sarcoidosis and sarcoid-like reaction following Hodgkin's disease. Report of two cases.
The occurrence of a sarcoidosis associated with Hodgkin's disease is an infrequent but well-described event. Moreover it has been described for many decades that some malignancies may present with simultaneous granulomatous manifestations named sarcoid-like reactions. To differentiate sarcoidosis from the sarcoid-like reactions is not an easy step in the final diagnosis. No author in the past has included the use of 2-deoxy-2[18F]fluoro-D-glucose positron emission tomography (FDG-PET) in order to help in this differentiation. We report two patients with Hodgkin's disease complicated with a typical form of sarcoidosis and with diffuse sarcoid-like reactions. We discuss the use of FDG-PET as a tool in the making of the final diagnosis and the difficulties associated with this technique in the interpretation of different hypermetabolic tissues.
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000494:pharmacology*; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007249:Inflammation; D008875:Middle Aged; D019275:Radiopharmaceuticals / Q000494:pharmacology*; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis*; D013997:Time Factors; D014055:Tomography, Emission-Computed / Q000379:methods*; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18