title: Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens.
abstract: Crude extracts from the fruiting bodies of Omphalotus illudens displayed activity in the HSV-I/CV-1 antiviral assay. Bioactivity-guided isolation led to the known compound illudin S (1) as the sole antiviral component present in these extracts.
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002478:Cells, Cultured / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D000882:Haplorhini; D018259:Herpesvirus 1, Human / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C008105:illudin S