title: Enhancement of cesium-137 excretion by rats treated with acetazolamide.
abstract: Acetazolamide (10 mg/kg, intraperitoneally) increases the urinary excretion of cesium-137 in the rat. Meralluride (6.8 mg of Hg per kilogram, subcutaneously) blocks the effect of acetazolamide on the cesium-137 excretion without any influence on the urine volume and pH of the urine. This indicates that acetazolamide increases the urinary excretion of cesium-137 by increasing its secretion through the renal tubule in the same manner as it increases the excretion of potassium and rubidium-86.
mesh_terms: D000086:Acetazolamide / Q000494:pharmacology*; D000818:Animals; D002586:Cesium; D002588:Cesium Radioisotopes; D011188:Potassium; D051381:Rats
chemical_list: D002588:Cesium Radioisotopes; D002586:Cesium; D000086:Acetazolamide; D011188:Potassium
keywords: ACETAZOLAMIDE/pharmacology; CESIUM/radioactive