Pseudomyxoma peritonei: a review of 62 cases.
OBJECTIVE
Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth.


METHODS
Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed.


RESULTS
Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n=38) had a better survival (p=0.0008) than those with more focal proliferation (n=14).


CONCLUSIONS
In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.
D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D011553:Pseudomyxoma Peritonei / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D016019:Survival Analysis