Strategies for mycobacterial genetics.
Molecular genetics is one of the most rational approaches to determine particular gene functions. Inactivation of putative virulence genes is a powerful tool not only for characterization of pathogenic bacteria. This review summarizes recently described strategies for DNA transfer and gene inactivation in mycobacteria.
D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000032:analysis; D020868:Gene Silencing; D009160:Mycobacteriophages / Q000235:genetics; D009161:Mycobacterium / Q000187:drug effects / Q000235:genetics* / Q000502:physiology; D016376:Oligonucleotides, Antisense / Q000494:pharmacology; D014158:Transcription, Genetic; D014170:Transformation, Genetic; D014774:Virulence / Q000235:genetics*
D004269:DNA, Bacterial; D016376:Oligonucleotides, Antisense