[Monitoring ischemia-/reperfusion syndrome in abdominal aortic aneurysm--conventional operation versus stent implantation].
From a biochemical point of view, our study corroborates the suggestion that implantation of a stent graft is less invasive than conventional surgery for infrarenal aortic aneurysm. In general, ischemia during open aortic surgery lasts shorter but affects a much greater part of the body than stent implantation. Eventration before, and more pronounced reperfusion following conventional repair cause marked intra-operative increases in TxB2, 6-keto-PGF1 alpha, and sICAM-1 levels. Thromboxane obviously is generated mainly in the reperfused tissues, whereas 6-keto-PGF1 alpha is produced in the eventrated bowel. sICAM-1 is released from both.
D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D006801:Humans; D007431:Intraoperative Complications / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D007866:Leg / Q000098:blood supply*; D010043:Outcome and Process Assessment, Health Care; D015427:Reperfusion Injury / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D015607:Stents