Cushing's syndrome associated with adenocarcinoma of the lung.
Paraneoplastic Cushing's syndrome caused by ectopic adrenocorticotropin production has been reported in association with a variety of malignant tumors. However, most cases of this syndrome are associated with neuroendocrine tumors such as small-cell lung cancer (SCLC), carcinoid tumors, and medullary carcinoma of the thyroid. We present a 49-year-old man who developed Cushing's syndrome associated with adenocarcinoma of the lung. He had a wide variety of clinical symptoms and comorbidity related to this syndrome during the course, and died 4 months after the diagnosis. This is a very rare case report of Cushing's syndrome associated with adenocarcinoma of the lung.
D000182:ACTH Syndrome, Ectopic / Q000209:etiology* / Q000503:physiopathology; D000230:Adenocarcinoma / Q000150:complications* / Q000556:secondary; D003480:Cushing Syndrome / Q000209:etiology* / Q000503:physiopathology; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000556:secondary; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging