Angiosarcoma in a chronically lymphedematous leg: an unusual presentation of Stewart-Treves syndrome.
Angiosarcoma arising from chronic lymphedema is referred to as Stewart-Treves syndrome. It typically occurs as a complication of long-lasting lymphedema of the arm after mastectomy and/or radiotherapy for breast cancer. Angiosarcoma associated with idiopathic lymphedema of the lower extremity is extremely rare. We report a case of diffuse angiosarcoma of the leg in a patient with a 25-year history of idiopathic lymphedema. Despite rapid aggressive surgical treatment, the patient died 6 weeks after diagnosis.
D000671:Amputation, Surgical; D001706:Biopsy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004604:Elephantiasis / Q000150:complications*; D004886:Erysipelas / Q000150:complications; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012008:Recurrence; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013577:Syndrome; D013997:Time Factors; D014057:Tomography, X-Ray Computed