The effect of herbal remedy on the development of Trichinella spiralis infection in mice.
The effect of Alchinal (a complex preparation consisting of three substances: Echinacea purpurea extract, Allium sativum extract, cocoa) on the development of Trichinella spiralis infection in mice was studied. The preparation was administered to the animals orally, twice a day in 30 microl doses for 10 days after infecting mice with Trichinella larvae (500 larvae per mouse). It was demonstrated that after Alchinal administration, the number of adult forms (10 dpi--days post infection) and muscular larvae (36 dpi) significantly decreased. It is suggested that the remedy studied causes antiparasitic immunity enhancement in mice. Modulation of immunity by individual component(s) and/or joint action of the substances contained in Alchinal increases the antiparasitic defence of the organism.
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology*; D000284:Administration, Oral; D000818:Animals; D002099:Cacao; D020900:Echinacea; D005737:Garlic; D051379:Mice; D008807:Mice, Inbred BALB C; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D010946:Plants, Medicinal; D017160:Trichinella spiralis / Q000276:immunology / Q000472:pathogenicity; D014235:Trichinellosis / Q000276:immunology*
D000276:Adjuvants, Immunologic; D010936:Plant Extracts; C479540:alchinal