title: Nuclear and unclear functions of SUMO.
abstract: Post-translational modification by the ubiquitin-like SUMO protein is emerging as a defining feature of eukaryotic cells. Sumoylation has crucial roles in the regulatory challenges that face nucleate cells, including the control of nucleocytoplasmic signalling and transport and the faithful replication of a large and complex genome, as well as the regulation of gene expression.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D006801:Humans; D025842:SUMO-1 Protein / Q000502:physiology*; D014158:Transcription, Genetic / Q000502:physiology
chemical_list: D025842:SUMO-1 Protein