The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin.
Alpha-sulfanyl N-aryl acetamides, attached to resin via the sulfur atom, undergo efficient Pummerer cyclisation upon activation of the sulfur link, to give oxindoles; heterocyclic products can be cleaved from the resin in a traceless manner using samarium(II) iodide.