title: Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo.
abstract: The adducin family of cytoskeletal proteins are known to mediate actin driven cell movements. Here we describe the cloning and expression pattern of a gene encoding gamma-adducin in the chick embryo. Expression of this gene is strikingly restricted to the epithelial cell layer (with a few exceptions including emerging notochord and lateral mesoderm). Gamma-adducin is detected at particularly high levels in cell populations undergoing important morphogenetic movements, such as epiblast approaching the primitive streak, regressing spinal cord primordia and closing neural tube.
mesh_terms: D000818:Animals; D002465:Cell Movement; D002642:Chick Embryo; D005775:Gastrula; D008648:Mesoderm; D008969:Molecular Sequence Data; D009024:Morphogenesis; D009672:Notochord