Relationship between febrile urinary tract infection and urodynamics in myelodysplastic children with vesicoureteral reflux.
OBJECTIVE
We conducted a retrospective study in order to identify factors that may predict the incidence of febrile urinary tract infection (UTI) in myelodysplastic children with vesicoureteral reflux (VUR).


METHODS
A total of 23 myelodysplastic children with persistent VUR who were managed by clean intermittent catheterization (CIC) were eligible for this study. Any factors, including urodynamic parameters and urinary tract abnormalities, that may have been associated with the incidence of febrile UTI were evaluated using both univariate analysis and multiple logistic regression analysis.


RESULTS
Of 23 patients, 10 (43%) had had one or more episodes of febrile UTI. Both univariate and multivariate analyses showed a statistically significant relationship between low bladder compliance (<10 ml/cm H(2)O) and episodes of febrile UTI.


CONCLUSIONS
These results demonstrated that the urodynamics linked to bladder function disorder in the filling phase appear to be correlated with the incidence of febrile UTI in myelodysplastic children with VUR who are managed by CIC.
D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000503:physiopathology; D006801:Humans; D008297:Male; D009436:Neural Tube Defects / Q000150:complications / Q000503:physiopathology*; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000150:complications / Q000503:physiopathology*; D014563:Urodynamics; D014718:Vesico-Ureteral Reflux / Q000150:complications / Q000503:physiopathology*