[Effect of Daflon 500 mg on reperfusion damage following ischemia and reperfusion of striated muscle].
The results of the current study indicate that Daflon 500 mg effectively reduces permeability for macromolecules induced by ischemia-reperfusion, thus reducing postischemic edema formation in the early reperfusion period. The inhibitory effect of Daflon 500 mg on leukocyte emigration may account for the reduction of edema formation in the postischemic tissue and favor the therapeutic use Daflon 500 mg of reperfusion-injury.
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects / Q000276:immunology; D006224:Cricetinae; D004145:Diosmin / Q000494:pharmacology*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000276:immunology; D007958:Leukocyte Count; D008647:Mesocricetus; D008856:Microscopy, Fluorescence; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D015427:Reperfusion Injury / Q000276:immunology*; D012884:Skin Window Technique
D004145:Diosmin