Identification of new okadaic acid derivatives from laboratory cultures of Prorocentrum lima.
The dinoflagellate Prorocentrum lima produces toxins involved in the red tide phenomenon known as diarrhetic shellfish poisoning (DSP). This paper reports the isolation and spectroscopic structural elucidation of new compounds related to DSP toxins, isolated from a laboratory culture of strain PLV2. Their structures were established from their spectroscopic data.
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004141:Dinoflagellida / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019319:Okadaic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
C440968:DTX-6 compound; D008387:Marine Toxins; D019319:Okadaic Acid