Single dose povidone-iodine on thyroid functions and urinary iodine excretion.
The effect of single dose povidone-iodine on serum thyrotropin and thyroxine levels and urinary iodine excretion in 30 preterm, 40 full-term newborns and 50 infants at Dr. Sami Ulus Children's Hospital was studied. There was no significant change of thyroid function in any of the groups (p>0.05). Urinary iodine excretion in preterm and full-term groups elevated significantly (p<0.05). The authors conclude that patients who receive single dose povidone-iodine for skin disinfection are not at risk for thyroid disorders.
D000279:Administration, Cutaneous; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004203:Disinfection / Q000379:methods; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature / Q000652:urine*; D007455:Iodine / Q000652:urine*; D008297:Male; D011206:Povidone-Iodine / Q000008:administration & dosage*; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000187:drug effects*; D013963:Thyroid Hormones / Q000097:blood
D000891:Anti-Infective Agents, Local; D013963:Thyroid Hormones; D011206:Povidone-Iodine; D007455:Iodine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine