title: Late infection of a total knee arthroplasty with Streptococcus bovis in association with carcinoma of the large intestine.
abstract: Infection of a total knee arthroplasty with Streptococcus bovis in a 76-year-old man that led to the diagnosis of a bowel carcinoma is reported. Investigation revealed a malignancy in the ascending colon with extension into the adrenal gland. S bovis in conjunction with colonic neoplasia has been reported in several orthopedic conditions: vertebral osteomyelitis, discitis, lateral neck abscess, and osteomyelitis of the ileum. The relationship of S bovis to endocarditis, meningitis, brain abscesses, and peritonitis has also been well described. However, S bovis is a rare pathogen infecting joint prostheses and should raise the possibility of a gastrointestinal lesion.
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000150:complications* / Q000601:surgery; D000368:Aged; D003110:Colonic Neoplasms / Q000150:complications* / Q000601:surgery; D006801:Humans; D007720:Knee Prosthesis / Q000382:microbiology; D008297:Male; D016459:Prosthesis-Related Infections / Q000150:complications* / Q000382:microbiology*; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology*; D016985:Streptococcus bovis / Q000302:isolation & purification*