[Extent of bacterial contamination is a derminant fur microvascular damage in soft tissue infection].
With the use of intravital microscopy, we demonstrate that the extent of bacterial contamination is a determinant for the microvascular response and consecutively the microvascular injury. The model of bacterial soft tissue infection used, ideally allows to study the influence of foreign materials on microvascular immune response.
D000818:Animals; D006224:Cricetinae; D004730:Endothelium, Vascular / Q000503:physiopathology; D008833:Microcirculation / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000098:blood supply*; D012867:Skin / Q000098:blood supply*; D018461:Soft Tissue Infections / Q000503:physiopathology*; D013203:Staphylococcal Infections / Q000503:physiopathology*; D014946:Wound Infection / Q000503:physiopathology*