[Effectiveness of preoperative radio-chemo-thermotherapy with respect to thermometry in locally advanced rectal carcinoma].
Additional hyperthermia is able to intensify the effect of radio-chemotherapy in locally advanced rectal cancer. The datas represents favourable locally effect, if the necessary parameters of thermometry are achieved. We could demonstrate a correlation between temperatures and downstaging of the primary tumor. Consequently, aim of further developments is to optimize hyperthermia technology.
D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced; D002955:Leucovorin / Q000008:administration & dosage*; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D012007:Rectum / Q000473:pathology; D013821:Thermometers; D016896:Treatment Outcome
D002955:Leucovorin; D005472:Fluorouracil