title: [Anal and palmar contact dermatitis caused by iodopropynyl butylcarbamate in moist sanitary wipes].
abstract: A 63-year old man developed severe perianal and palmar contact dermatitis caused by sensitization to iodopropynyl butylcarbamate in moist sanitary wipes. Iodopropynyl butylcarbamate is increasingly employed as preservative in common cosmetic formulations and moist sanitary wipes as substitute for the previously frequently used sensitizers isothiazolinones and methyldibromoglutaronitrile. The allergic potential of diverse preservatives is a serious problem for the cosmetic industry, since truly hypoallergenic preservatives are not available but products such as moist sanitary wipes in large packages definitely require some form of protection.
mesh_terms: D000485:Allergens; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001004:Anus Diseases / Q000139:chemically induced* / Q000188:drug therapy; D002219:Carbamates / Q000009:adverse effects / Q000276:immunology*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000188:drug therapy; D006795:Household Products / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068656:Mometasone Furoate; D010209:Paper; D011244:Pregnadienediols / Q000008:administration & dosage / Q000627:therapeutic use; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D012882:Skin Tests; D013997:Time Factors
chemical_list: D000485:Allergens; D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D002219:Carbamates; D011244:Pregnadienediols; D011310:Preservatives, Pharmaceutical; D000068656:Mometasone Furoate; C106572:3-iodo-2-propynylbutylcarbamate