title: Size distribution of "informational" RNA.
abstract: Previous investigations suggested that the size of "informational" or "messenger" RNA was confined to sedimentation rates lying between 8 and 14S. These involved procedures permitting extended contact of the RNA with enzymatically active extracts. The present study re-examined the size distribution of T2-complementary RNA isolated by a method which minimized enzymatic degradation. A much greater diversity in size distribution (4S to 25S) was observed. Experiments are described indicating that 8 to 12S informational RNA does not readily attach to the 16S and 23S ribosomal components under the conditions used for sedimentation analysis.
mesh_terms: D004926:Escherichia coli / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*; D012333:RNA, Messenger; D012270:Ribosomes
chemical_list: D012333:RNA, Messenger; D012313:RNA
keywords: ESCHERICHIA COLI/chemistry; RIBONUCLEIC ACID/chemistry