Measles outbreak in a suburb of Tokyo, Japan, in 1998-1999.
A 1998-1999 outbreak of measles in Kawasaki City was studied to provide an up-to-date epidemiological understanding of the disease in Japan. 21 of the 69 total patients (30.4%) seen at the hospital were under 1 y of age. None of the 69 patients had received measles vaccine. 43 out of 50 nasopharyngeal swabs subjected to polymerase chain reaction assay (86%) were positive for the hemagglutinin (H) gene. The measles strain isolated from patients was classified as a D3 genotype. Such outbreaks are important epidemiologically, and these findings shed light on vaccination and immunity patterns in this urban population.
D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007115:Immunization Schedule; D015994:Incidence; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D008457:Measles / Q000453:epidemiology*; D008458:Measles Vaccine / Q000008:administration & dosage*; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D013383:Suburban Population; D014041:Tokyo / Q000453:epidemiology; D014611:Vaccination / Q000592:standards* / Q000639:trends
D008458:Measles Vaccine