Hematological studies of Parquetina nigrescens on haemorrhagic anaemic rats.
The effect of administration of aqueous extract of Parquetina nigrescens on haematological parameters was investigated in haemorrhagic anaemic rats from which about 30% of blood volume was removed through ocular vein under chloroform anesthesia. Anaemic rats were administered 400 mg/kg, 800 mg/kg and 1600 mg/kg of P. nigrescens aqueous extract daily for four weeks. Significant (P < 0.05) progressive and dose related increases were observed in red blood cell count (RBC, 10(6)/ml), Haemoglobin (gm/dl), Haematocrit (Hct, %) and Reticulocyte (%) while a decrease in white blood cell count (WBC 10(3) microl) was observed in test rats treated with aqueous extract of P. nigrescens when compared with both normal and bled control rats.
D000740:Anemia / Q000188:drug therapy* / Q000209:etiology*; D000818:Animals; D001769:Blood / Q000187:drug effects*; D001772:Blood Cell Count; D004195:Disease Models, Animal; D006470:Hemorrhage / Q000150:complications* / Q000188:drug therapy*; D031109:Periploca; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D010936:Plant Extracts