title: Primary amoebic meningoencephalitis in a patient with systemic lupus erythematosus.
abstract: This report describes a case of primary amoebic meningoencephalitis in a patient with systemic lupus erythematosus. No specific exposure was identified. Treatment with intravenous amphotericin B was associated with marked clinical improvement, but subsequent fatal relapse while still on therapy.
mesh_terms: D000328:Adult; D000562:Amebiasis / Q000150:complications / Q000276:immunology*; D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D008590:Meningoencephalitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D009253:Naegleria / Q000302:isolation & purification*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D000666:Amphotericin B