title: [Different mechanisms in intestinal paralysis in edematous and necrotizing pancreatitis of the rat].
abstract: The influence of experimental pancreatitis on bowel motility was measured in vivo with the propulsion technique and in vitro as contractility of isolated ileum muscle strips. In edematous pancreatitis, propulsion was reduced but contractility was normal. Both, propulsion and contractility were reduced in necrotizing pancreatitis. The intravenous saline infusion normalized propulsion in edematous pancreatitis but was of no benefit in necrotising pancreatitis. These results indicate that extraintestinal (neuroendocrine) regulation pathways were effected in edematous pancreatitis. Necrotising pancreatitis appears to have an additional profound influence on the intrinsic, intramural regulation of motility.
mesh_terms: D000818:Animals; D004487:Edema / Q000503:physiopathology*; D005769:Gastrointestinal Motility / Q000502:physiology*; D007077:Ileal Diseases / Q000503:physiopathology*; D007082:Ileum / Q000503:physiopathology; D066298:In Vitro Techniques; D007418:Intestinal Pseudo-Obstruction / Q000503:physiopathology*; D008297:Male; D009490:Neurosecretory Systems / Q000503:physiopathology; D010195:Pancreatitis / Q000503:physiopathology*; D019283:Pancreatitis, Acute Necrotizing / Q000503:physiopathology*; D010528:Peristalsis / Q000502:physiology; D051381:Rats; D013050:Spectrometry, Fluorescence