[Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells].
OBJECTIVE
To evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells.


METHODS
Apoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique.


RESULTS
Apoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01).


CONCLUSIONS
Ct infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.
D000328:Adult; D017209:Apoptosis; D002690:Chlamydia Infections / Q000150:complications / Q000473:pathology*; D002692:Chlamydia trachomatis; D006801:Humans; D020287:In Situ Nick-End Labeling; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D013090:Spermatocytes / Q000473:pathology*; D013194:Staining and Labeling