Olanzapine for recurrent aggression in a patient with temporal lobe epilepsy who had temporal lobectomy.
We report the case of a patient with epilepsy who had interictal severe affective aggression, and whose epilepsy significantly improved (but not aggression) after successful temporal lobectomy. Olanzapine significantly improved these aggressive episodes refractory to neurosurgery and previous pharmacological treatments including antipsychotics, anticonvulsants/mood stabilizers and benzodiazepines.
D000328:Adult; D000374:Aggression / Q000187:drug effects* / Q000523:psychology; D038481:Anterior Temporal Lobectomy; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use*; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D006801:Humans; D008297:Male; D000077152:Olanzapine; D012008:Recurrence
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine