[Pilocytic astrocytoma and diencephalic syndrome in an adult with neurofibromatosis type 1].
We report a rare case of pilocytic astrocytoma and diencephalic syndrome occurring together in a 30-year-old woman with neurofibromatosis type 1 (NF-1). Diencephalic syndrome included emaciation and somnolence. Gadolinium-enhanced magnetic resonance imaging revealed a brain tumor in the optic chiasmal-hypothalamic region, which invaded the thalamus, brain stem and cerebellum. A biopsy specimen from the chiasmal tumor was compatible with pilocytic astrocytoma. Although she received radiation therapy, she died 22 months after the onset of the disease.
D000328:Adult; D001254:Astrocytoma / Q000150:complications*; D001932:Brain Neoplasms / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007027:Hypothalamic Diseases / Q000209:etiology*; D007031:Hypothalamus; D009361:Neoplasm Invasiveness; D009456:Neurofibromatosis 1 / Q000150:complications*; D009897:Optic Chiasm; D019574:Optic Nerve Neoplasms / Q000150:complications / Q000473:pathology