Long-term management of bilateral metastases of renal cell carcinoma to the choroid plexus.
BACKGROUND
Metastatic tumors to the brain presenting exclusively in the choroid plexus are exceedingly rare. These events are frequently associated with renal cell carcinoma (RCC), of which all reported cases have been solitary lesions.


METHODS
The authors present the unusual case of a patient with metastatic RCC who developed bilateral tumors of the choroid plexus. These tumors, one of which was confirmed to be metastatic RCC by histologic analysis, were treated over a 5-year period with a combination of interventions, including surgical resection, stereotactic radiosurgery, and chemotherapy, in conjunction with continual radiological monitoring.


RESULTS
Follow-up over a 5-year period demonstrated good control of the patient's intracranial disease and very little neurologic sequelae.


CONCLUSIONS
This strategy was successful in keeping the patient in good health with minimal neurological symptoms, despite the bilateral nature of the disease and its generally poor prognosis.
D002292:Carcinoma, Renal Cell / Q000556:secondary* / Q000628:therapy*; D016545:Choroid Plexus Neoplasms / Q000556:secondary* / Q000628:therapy*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008875:Middle Aged; D013997:Time Factors