DNA-templated self-assembly of protein arrays and highly conductive nanowires.
A DNA nanostructure consisting of four four-arm junctions oriented with a square aspect ratio was designed and constructed. Programmable self-assembly of 4 x 4 tiles resulted in two distinct lattice morphologies: uniform-width nanoribbons and two-dimensional nanogrids, which both display periodic square cavities. Periodic protein arrays were achieved by templated self-assembly of streptavidin onto the DNA nanogrids containing biotinylated oligonucleotides. On the basis of a two-step metallization procedure, the 4 x 4 nanoribbons acted as an excellent scaffold for the production of highly conductive, uniform-width, silver nanowires.
D019921:Biotinylation; D004247:DNA / Q000737:chemistry; D004553:Electric Conductivity; D018625:Microscopy, Atomic Force; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D040081:Protein Array Analysis; D012834:Silver; D019809:Streptavidin / Q000737:chemistry
D009838:Oligodeoxyribonucleotides; D012834:Silver; D004247:DNA; D019809:Streptavidin