The use of topical ketorolac 0.5% for pain relief following cyclophotocoagulation.
OBJECTIVE
Laser cycloablation is frequently used for glaucoma palliation. Although usually successful, the procedure is often accompanied by pain. The purpose of this prospective, randomized study was to study topical ketorolac for the amelioration of pain following cycloablation.


METHODS
Thirty-six patients requiring a cyclodestructive procedure were randomized into two groups. Each group received a standardized cycloablative laser procedure and routine postoperative drops. Patients were randomized to receive additional topical ketorolac or not. Patients indicated by a mark on a standardized 100-mm line their subjective experience of pain.


RESULTS
There were no differences between the patient groups regarding preoperative demographic factors. There was a significant difference between the groups in the average and daily pain rating, with the ketorolac therapy group reporting significantly less pain.


CONCLUSIONS
The addition of topical ketorolac significantly lessened the pain reported by patients following a cyclodestructive laser procedure.
D000287:Administration, Topical; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002924:Ciliary Body / Q000601:surgery*; D004359:Drug Therapy, Combination; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D020910:Ketorolac / Q000008:administration & dosage / Q000627:therapeutic use*; D017075:Laser Coagulation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D010147:Pain Measurement / Q000379:methods; D010149:Postoperative Pain / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D011446:Prospective Studies; D012449:Safety; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009883:Ophthalmic Solutions; C009935:prednisolone acetate; D011239:Prednisolone; D020910:Ketorolac