[Respiratory burst and phagocytosis activity in patients with infection after surgical abdominal interventions].
Phagocyte functions such as respiratory burst or phagocytic activity allow the determination of septic courses. Already in case of surgical stress a reduced constitutive generation of reactive oxygen metabolites could be shown, which is assumed to influence the outcome of following septic courses. The results of septic patients suggest that in spite of a functioning uptake of particles and germs (phagocytosis) a defect of intracellular killing (respiratory burst) exists.
D000005:Abdomen / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis / Q000276:immunology*; D011379:Prognosis; D017382:Reactive Oxygen Species / Q000378:metabolism; D016897:Respiratory Burst / Q000276:immunology*; D013530:Surgical Wound Infection / Q000276:immunology*
D017382:Reactive Oxygen Species