[Complete recovery of hungry bone syndrome using intravenous calcium infusion. Report of one case].
We report a 29 years old woman with a highly symptomatic primary hyperparathyroidism. After parathyroid adenoma excision, she presented a prolonged and life threatening hypocalcemia, due to a severe hungry bone syndrome. Conventional treatment with oral and intravenous calcium and calcitriol supplementation failed to raise serum and urinary calcium or to relief symptoms. After one month, we indicated a continuous intravenous calcium infusion allowing, during 6 months, an adequate outpatient management. Initial T scores for bone density were markedly low (L2-L4: -3.14; femoral neck: -3.07) and they increased 17% after 18 days of calcium infusion. After 147 days of treatment bone density was normal, increasing by 61%. The present case shows that the hungry bone syndrome can be a real risk for patients and a complex therapeutic challenge. With an appropriate calcium supply an early, fast and complete recovery of bone mass can be achieved.
D000236:Adenoma / Q000150:complications / Q000601:surgery; D000328:Adult; D000469:Alkaline Phosphatase / Q000032:analysis; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000175:diagnosis / Q000188:drug therapy*; D001861:Bone Regeneration; D002117:Calcitriol / Q000008:administration & dosage; D002118:Calcium / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000601:surgery; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology*; D007262:Infusions, Intravenous; D010282:Parathyroid Neoplasms / Q000150:complications / Q000601:surgery; D013577:Syndrome
D000469:Alkaline Phosphatase; D002117:Calcitriol; D002118:Calcium