[rG-CSF improves tissue regeneration in neutropenia-induced disorders of wound healing].
The effect of rG-CSF on wound healing in neutropenic mice was studied in the wound healing model on the ear of hairless mice. Animals were treated with a daily dose of rG-CSF (i.p.; 3 micrograms). rG-CSF significantly improved wound healing probably by modulation of the cellulary immune response.
D000818:Animals; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D051379:Mice; D008812:Mice, Hairless; D018919:Neovascularization, Physiologic / Q000187:drug effects* / Q000276:immunology; D009503:Neutropenia / Q000276:immunology*; D011994:Recombinant Proteins / Q000494:pharmacology; D014945:Wound Healing / Q000187:drug effects* / Q000276:immunology
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor