Reversed intrapulmonary right-to-left shunt after banding of the patent ductus venosus.
Diffuse pulmonary microvascular arteriovenous communication developed in an 8-year-old girl with a patent ductus venosus. Tc-99m macroaggregated albumin (MAA) pulmonary perfusion scintigraphy with total-body imaging demonstrated multiple lung perfusion deficits and abnormal tracer uptake in systemic organs with hepatic radioactivity greater than the kidneys, suggesting the presence of right-to-left shunt and abnormal hepatic hemodynamics. I-123 iodoamphetamine transrectal portal scintigraphy revealed a large portosystemic venous shunt. The follow-up Tc-99m MAA perfusion scans after banding of the patent ductus venosus revealed partial improvement of the perfusion deficits and right-to-left shunt, indicating the possible reversibility of this pulmonary shunt complication.
D002648:Child; D005260:Female; D006801:Humans; D020367:Iofetamine; D008099:Liver / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D011167:Portacaval Shunt, Surgical; D011169:Portal Vein / Q000002:abnormalities* / Q000000981:diagnostic imaging* / Q000601:surgery; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D014652:Vascular Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D014682:Vena Cava, Inferior / Q000002:abnormalities* / Q000000981:diagnostic imaging* / Q000601:surgery
D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D020367:Iofetamine