title: Activation of DNA-degrading enzymes during apoptosis.
abstract: Cell death by apoptosis requires a precise plan of destruction of DNA and proteins. In this paper, we review the current knowledge on the different DNA-degrading enzymes which are activated in apoptotic cells. The activation of DNases by upstream proteases is also discussed.
mesh_terms: D000818:Animals; D017209:Apoptosis; D003851:Deoxyribonucleases / Q000378:metabolism*; D004720:Endonucleases / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism; D004789:Enzyme Activation; D006801:Humans
chemical_list: D003851:Deoxyribonucleases; D004720:Endonucleases; D010450:Endopeptidases