[The hypothalamic-hypophyseal-gonadal system and its functional reserve during long-term vibration and noise].
Male rats were exposed to influence of vibration and noise in a drown chamber for 4 hours 5 times a week during 4 months. The corrected velocity of vibration was 4.58 x 10(-2) m/s. Steady broadland noise with the level of sound of 92 dBA covered the standardized range of frequencies, starting with 63 Gc. The noise caused earlier and more expressed changes in functional gonadotropic reserves of the hypothalamic-hypophyseal complex as compared to those changes when it was used in combination with vibration. By 4-th month of the experiment these reserves reduced. Gonadotropic activity of the hypophysis has been determined to change in a phase way--from its considerable increase to the norm. The changes in gonadotropic reserves of the hypothalamic-hypophyseal complex were not accompanied by remarkable changes in the gonadal activity.
D000726:Androgen Antagonists / Q000494:pharmacology; D000818:Animals; D005485:Flutamide / Q000494:pharmacology; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000502:physiology*; D008297:Male; D009622:Noise / Q000009:adverse effects*; D051381:Rats; D013737:Testis / Q000187:drug effects / Q000502:physiology*; D013739:Testosterone / Q000097:blood; D013997:Time Factors; D014732:Vibration / Q000009:adverse effects*
D000726:Androgen Antagonists; D013739:Testosterone; D005485:Flutamide