Clathrin-dependent endocytosis.
The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
D033962:Adaptor Protein Complex 2 / Q000502:physiology; D000818:Animals; D019390:Arrestins / Q000502:physiology; D002135:Calcium-Binding Proteins; D002462:Cell Membrane / Q000378:metabolism / Q000648:ultrastructure; D002966:Clathrin / Q000032:analysis / Q000502:physiology*; D003034:Coated Pits, Cell-Membrane / Q000737:chemistry / Q000378:metabolism / Q000648:ultrastructure; D018699:Coated Vesicles / Q000737:chemistry; D004705:Endocytosis; D008562:Membrane Glycoproteins / Q000502:physiology; D009419:Nerve Tissue Proteins / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D015398:Signal Transduction; D050857:Synaptotagmins; D000071557:beta-Arrestins
D033962:Adaptor Protein Complex 2; D019390:Arrestins; D002135:Calcium-Binding Proteins; D002966:Clathrin; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D011956:Receptors, Cell Surface; D000071557:beta-Arrestins; D050857:Synaptotagmins