title: Humoral antibody response of Atlantic salmon, Salmo salar L., vaccinated against Moritella viscosa.
abstract: Immunization of Atlantic salmon, Salmo salar L., with experimental vaccine for protection against M. viscosa was tested. The antigen preparation used for the comparative studies was sonicate formalin killed M. viscose unwashed bacteria. Vaccination was carried out by intraperitoneal injection of bacterin in Biojec mineral oil as an adjuvant. When accumulated mortality in the control group with PBS of fish challenged by i.p. injection of M. viscose reached 100% with a challenge dose of 2.3 x 10(6) CFU, mortality in the experimental group was 71.23%. A positive correlation between the survival rates and corresponding median antibody levels of each group was found at the challenge time.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005393:Fish Diseases / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D007107:Immune System / Q000187:drug effects; D007274:Injections, Intraperitoneal / Q000662:veterinary; D034221:Moritella / Q000276:immunology*; D020317:Salmo salar; D016019:Survival Analysis; D016896:Treatment Outcome; D014611:Vaccination / Q000662:veterinary; D014735:Vibrio Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines