Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode.
The influence of K(7)Fe(3+)P(2)W(17)O(62)H(2) on l-alpha-phosphatidylcholine/cholesterol bilayer lipid membrane on Pt electrode was studied by voltammetry and AC impedance spectroscopy. The interaction of the polyoxometalates with the BLM can promote the access of Ru(NH(3))(6)(3+) and [Fe(CN)(6)](3-/4-) to the electrode surface. It was found that some kind of pores had been formed on the BLM by AFM. The phenomenon is attributed to the interaction of K(7)Fe(3+)P(2)W(17)O(62)H(2) with phosphatidylcholine phosphate groups located in its outer leaflet. Experimental results are helpful to understand the biological activity of the polyoxometalates in vivo.
D000818:Animals; D002645:Chickens; D002784:Cholesterol / Q000737:chemistry; D017097:Electric Impedance; D004563:Electrochemistry; D004566:Electrodes; D005290:Ferric Compounds / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D010087:Oxides / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*; D016062:Porosity
D005290:Ferric Compounds; C488539:K7FeP2W17O62H2; D008051:Lipid Bilayers; D010087:Oxides; D010713:Phosphatidylcholines; D010984:Platinum; D002784:Cholesterol