Highly selective binding of metal ions to thymine-thymine and cytosine-cytosine base pairs in DNA duplexes.
Very specific binding of of Hg(II) and Ag(I) cations unexpectedly and significantly stabilizes the naturally occurring miss-base pairs, thymine-thymine and cytosine-cytosine, in DNA duplexes.
D020029:Base Pairing; D001483:Base Sequence; D001665:Binding Sites; D003596:Cytosine / Q000378:metabolism*; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D008670:Metals / Q000378:metabolism*; D013941:Thymine / Q000378:metabolism*
D008670:Metals; D003596:Cytosine; D004247:DNA; D013941:Thymine