Tuboovarian abscess caused by Candida glabrata in a febrile neutropenic patient.
Deep-seated Candida infections are strongly associated with mortality and morbidity of patients, and need early diagnosis. The frequency of deep-seated fungal infection has recently been growing. We encountered a tuboovarian abscess caused by Candida glabrata after chemotherapy with an anticancer drug, methotrexate, in a febrile neutropenic patient. The susceptibilities to fluconazole and amphotericin B were 16 and 0.5 micro g/ml, respectively. Although combination therapy of fluconazole and amphotericin B was effective, left salpingectomy was laparoscopically performed because the left adnexal tumor continued to exist asymptomatically after 1 month.
D000038:Abscess / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D041221:Candida glabrata / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D005334:Fever; D015725:Fluconazole / Q000008:administration & dosage; D005831:Genital Diseases, Female / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D006828:Hydatidiform Mole / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000627:therapeutic use; D009503:Neutropenia; D011247:Pregnancy
D000935:Antifungal Agents; D000964:Antimetabolites, Antineoplastic; D016179:Granulocyte Colony-Stimulating Factor; D000666:Amphotericin B; D015725:Fluconazole; D008727:Methotrexate