Metal ion-directed outside binding of small DNA ligand.
DNA binding of the ligand bearing an oxine and a pyridinium group was regulated by coexisting Cu2+ over the binding constant range of three orders of magnitude. The ligands coordinated to Cu2+ to form a dimer and then cooperatively bound outside of DNA duplex to give the well-regulated 1-D structure along the DNA backbone.
D004247:DNA / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D008024:Ligands; D008670:Metals; D004247:DNA