title: Experimental model of continent colostomy using rectus abdominis neosphincteroplasty.
abstract: BACKGROUND
  Use of dynamic myoplasty to create a continent stoma has produced promising results, but long-term stoma continence has not been achieved. The aim of the study was to establish and test a new model.
  
  
  METHODS
  Three types of dynamic rectus abdominis sphincteroplasty around a colostomy and two conditioning protocols were tested in ten domestic pigs. Continence was assessed by means of conventional defaecography and neosphincter manometry after 8 and 12 weeks. The neosphincter muscle was studied histologically to assess the transformation of muscle type.
  
  
  RESULTS
  Use of a distal rectus muscle sling surrounding the stoma by 270 degrees with a low-frequency conditioning protocol achieved a continent colostomy for more than 12 h on each of 5 consecutive days. The neosphincter had a 40-mm high-pressure segment with mean pressure of 74 (range 67-82) mmHg. The proportion of type I muscle fibres increased from 38 (range 32-42) to 74 (range 66-78) per cent after 12 weeks of conditioning.
  
  
  CONCLUSIONS
  This pilot study demonstrated the feasibility of a continent stoma in an animal model with a dynamic rectus neosphincter. Long-term results should be confirmed in a larger series before use in humans can be considered.
mesh_terms: D000818:Animals; D001706:Biopsy / Q000379:methods; D003125:Colostomy / Q000379:methods*; D004558:Electric Stimulation; D005242:Fecal Incontinence / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D008365:Manometry; D011312:Pressure; D017568:Rectus Abdominis / Q000637:transplantation*; D013524:Surgical Flaps; D013552:Swine