[Drug induced anosmia with nifedipine].
BACKGROUND
Drug-induced dysosomia is rare and its prevalence difficult to estimate, notably because of the lack of satisfactory criteria of imputability.


METHODS
In a 59 year-old patient consulting for olfactory disorders that had progressed over the past 4 month, diagnosis of dysosomia secondary to the administration of nifedipine was maintained with a considerable score of imputability (negative clinical controls and partial regression of the disorder).


CONCLUSIONS
Drugs used in cardiology represent one of the major therapeutic classes that can lead to dysfunction in smell and/or taste. These drugs are nifedipine reported in 1985, metoprolol (beta blocker), diltiazem and, more recently, enalapril.
D002121:Calcium Channel Blockers / Q000009:adverse effects*; D006331:Heart Diseases / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects*; D000857:Olfaction Disorders / Q000139:chemically induced*
D002121:Calcium Channel Blockers; D009543:Nifedipine