title: Titin: properties and family relationships.
abstract: In striated muscles, the rapid production of macroscopic levels of force and displacement stems directly from highly ordered and hierarchical protein organization, with the sarcomere as the elemental contractile unit. There is now a wealth of evidence indicating that the giant elastic protein titin has important roles in controlling the structure and extensibility of vertebrate muscle sarcomeres.
mesh_terms: D000818:Animals; D064211:Connectin; D003599:Cytoskeleton / Q000378:metabolism; D006801:Humans; D008854:Microscopy, Electron; D005810:Multigene Family; D009124:Muscle Proteins / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000648:ultrastructure; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D012518:Sarcomeres / Q000378:metabolism
chemical_list: D064211:Connectin; D009124:Muscle Proteins; C577285:TTN protein, human; D011494:Protein Kinases