title: Biological networks: the tinkerer as an engineer.
abstract: This viewpoint comments on recent advances in understanding the design principles of biological networks. It highlights the surprising discovery of "good-engineering" principles in biochemical circuitry that evolved by random tinkering.
mesh_terms: D000818:Animals; D001669:Biochemical Phenomena; D001671:Biochemistry; D005075:Biological Evolution; D001695:Biology; D004247:DNA / Q000378:metabolism; D004738:Engineering; D008954:Models, Biological; D011506:Proteins / Q000378:metabolism; D015398:Signal Transduction; D013598:Systems Theory
chemical_list: D011506:Proteins; D004247:DNA