title: RNA interference and chemically modified siRNAs.
abstract: RNA interference (RNAi) represents one of the most promising new frontiers in drug discovery. Short double-stranded RNA molecules are able to sequence-specifically inhibit expression of genes. This young technology offers both opportunities and challenges to nucleic acid chemists.
mesh_terms: D034622:RNA Interference; D034741:RNA, Small Interfering / Q000737:chemistry*
chemical_list: D034741:RNA, Small Interfering