Evaluation of a whitening gel designed to accelerate whitening.
A clinical trial was conducted with 25 subjects to evaluate the effects and safety of Zoom! Take-Home whitening gel, a 6% hydrogen peroxide gel for vital tooth bleaching. Tooth bleaching was accomplished using a tray system overnight for 6 nights. Over the 6 nights, a significant change (from darker to lighter) was seen in tooth shades as demonstrated by 3 assessment methods: VITA Shade Value Oriented Guide, Trubyte Bioform Color Ordered Shade Guide scoring system, and the Chroma Meter CR-321 assessments. VITA Shade scores showed a mean change of -6.49 shades (P = .0001) from baseline to day 4 and a -7.72 shades (P = .0001) from baseline to day 7. The Trubyte scores showed a mean change of -9.31 shades (P = .0001) from baseline to day 4 and a -10.77 shades (P = .0001) from baseline to day 7. The Chroma Meter was used to measure tooth color. Analysis of Chroma Meter data showed a significant change in color (delta E), 13.82 mean score change (P = .0001) from baseline to day 4 and a 7.25 mean score change (P = .0001) from baseline to day 7. At day 4 minor tooth sensitivity was reported, and all tooth sensitivity resolved within a few days after treatment.
D000328:Adult; D003116:Color / Q000592:standards; D003742:Dental Devices, Home Care; D003807:Dentin Sensitivity / Q000209:etiology; D005069:Evaluation Studies as Topic; D005260:Female; D005782:Gels; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage; D008297:Male; D017063:Outcome Assessment, Health Care / Q000379:methods; D016877:Oxidants / Q000008:administration & dosage; D017060:Patient Satisfaction; D011795:Surveys and Questionnaires; D014073:Tooth Bleaching / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*
D005782:Gels; D016877:Oxidants; D006861:Hydrogen Peroxide