[Measuring blood flow velocity in healthy and indomethacin-induced inflammation in rat small intestine serosa with FITC-marked erythrocytes].
Intravital microscopy was performed in normal and indomethacin-induced intestinal inflammation at serosal postcapillary venules of the small bowel in rats. Standard parameters of microcirculation as red blood cell velocity, diameter of venules, blood flow and adherent leucocytes were successfully investigated using FITC-labelled red blood cells. Since postcapillary venules are responsible for the venous drainage of the inflammed small bowel segments this method is reliable and effective for further investigation of intestinal microcirculation under special conditions such as intestinal inflammation.
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D003424:Crohn Disease / Q000139:chemically induced / Q000503:physiopathology*; D004912:Erythrocytes; D007213:Indomethacin; D007413:Intestinal Mucosa / Q000098:blood supply*; D007958:Leukocyte Count; D008297:Male; D008853:Microscopy; D008856:Microscopy, Fluorescence; D018715:Microscopy, Video; D051381:Rats; D017207:Rats, Sprague-Dawley; D012700:Serositis / Q000139:chemically induced / Q000503:physiopathology*
D007213:Indomethacin