title: [Pharmaco-economic aspects of antidepressants and antipsychotic drugs].
abstract: This review summarizes results of cost-utility analyses done with newer versus older antidepressants as well as atypical versus conventional/typical neuroleptics/antipsychotics. Following descriptions of the methodological priniciples, the currently available studies (stimulation models) are presented and discussed critically. It can be stated that the economic value of different antidepressants and the atypical neuroleptics can not be decided definitively at the present time due to methodological reasons (e.g. lacking of randomized prospective studies). Increased quality of life of patients and their family seems true for the newer psychotropics, measurement is difficult, however, and a challenge for social and ethical discussions.
mesh_terms: D000928:Antidepressive Agents / Q000145:classification / Q000191:economics* / Q000627:therapeutic use; D018687:Antidepressive Agents, Second-Generation / Q000145:classification / Q000191:economics / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000145:classification / Q000191:economics* / Q000627:therapeutic use; D003362:Cost-Benefit Analysis / Q000706:statistics & numerical data; D003866:Depressive Disorder / Q000188:drug therapy / Q000191:economics*; D016527:Drug Costs / Q000706:statistics & numerical data*; D005858:Germany; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy / Q000191:economics*; D017367:Selective Serotonin Reuptake Inhibitors / Q000145:classification / Q000191:economics / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D018687:Antidepressive Agents, Second-Generation; D014150:Antipsychotic Agents; D017367:Selective Serotonin Reuptake Inhibitors