title: Use of a centrifugal vortex blood pump and heparin-bonded circuit for extracorporeal rewarming of severe hypothermia in acutely injured and coagulopathic patients.
abstract: BACKGROUND
  Standard rewarming methods for posttraumatic hypothermia are ineffective or require systemic heparinization. Centrifugal vortex blood pumps (CVBPs), heparin-bonded circuits, and, potentially, percutaneous access techniques, facilitate the institution of an extracorporeal circulation by noncardiac surgeons.
  
  
  METHODS
  Seven severely hypothermic patients requiring emergent operative intervention were rewarmed intraoperatively using the CVBP with heparin-bonded circuitry.
  
  
  RESULTS
  Patients were critically ill (average Injury Severity Score of 43.5 [SD, 13.6] for the traumatized patients). The mean temperature before rewarming was 31.5 degrees C (SD, 1.6 degrees C). The CVBP outflow site was the common femoral vein in all patients, with the inflow into the superficial femoral artery (n = 2), contralateral common femoral vein (n = 2), and internal jugular vein (n = 3). The mean time to rewarm to 37 degrees C was 73.3 (SD, 30.5) minutes. All patients survived the initial operation, although the ultimate survival was 43%.
  
  
  CONCLUSIONS
  Noncardiac surgeons can effectively use an extracorporeal rewarming strategy incorporating a heparin-bonded CVBP to rapidly rewarm hypothermic coagulopathic patients undergoing surgery.
mesh_terms: D000328:Adult; D000368:Aged; D001831:Body Temperature; D005260:Female; D006493:Heparin; D006801:Humans; D007035:Hypothermia / Q000628:therapy*; D015601:Injury Severity Score; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D017694:Rewarming / Q000295:instrumentation / Q000379:methods*; D013997:Time Factors; D014947:Wounds and Injuries / Q000209:etiology / Q000401:mortality / Q000601:surgery*
chemical_list: D006493:Heparin