An unusual cause of new-onset atrial flutter: primary cardiac lymphoma.
Primary cardiac lymphoma is a rare disease with a high mortality rate due to the advanced stage of myocardial involvement at presentation. The diagnosis is extremely difficult to make because of the rarity of the disease, variability of clinical manifestations, limited noninvasive diagnostic techniques available, and difficulties and/or delays in the use of invasive measures. The incidence of the disease is increasing, especially among immunocompromised patients, with those suffering from acquired immunodeficiency syndrome accounting for the greatest increase. We report the case of an immunocompetent 76-year-old black woman who presented with near-syncopal episodes. Transthoracic echocardiogram revealed a right atrial mass. Surgical resection was performed, and a diagnosis of large B-cell non-Hodgkin's lymphoma was made. Primary cardiac lymphoma should be considered in any patient with a cardiac mass. Prompt diagnosis and treatment of primary cardiac lymphoma is imperative for survival.
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D001282:Atrial Flutter / Q000209:etiology*; D001706:Biopsy; D006328:Cardiac Catheterization; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000009:adverse effects; D004317:Doxorubicin / Q000009:adverse effects; D017548:Echocardiography, Transesophageal; D017809:Fatal Outcome; D005260:Female; D005334:Fever / Q000139:chemically induced; D005434:Flow Cytometry; D006338:Heart Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007121:Immunocompetence; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008224:Lymphoma, Follicular / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D009503:Neutropenia / Q000139:chemically induced; D011241:Prednisone / Q000009:adverse effects; D011379:Prognosis; D018805:Sepsis / Q000139:chemically induced; D013575:Syncope / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000009:adverse effects
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone