Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything?
The mortality benefit associated with primary percutaneous coronary intervention in ST-segment elevation myocardial infarction may be lost if door-to-balloon time is delayed by >1 hour as compared with fibrinolytic therapy door-to-needle time. Interventional cardiology laboratories endeavoring to achieve the benefits of primary percutaneous coronary intervention seen in randomized clinical trials should aim to match their short door-to-balloon times.
D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data*; D006801:Humans; D016014:Linear Models; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy*; D012008:Recurrence; D020521:Stroke / Q000150:complications; D016019:Survival Analysis; D015912:Thrombolytic Therapy / Q000706:statistics & numerical data*; D013997:Time Factors; D016896:Treatment Outcome