A simple one-pot method for the synthesis of partially protected mono- and disaccharide building blocks using an orthoesterification-benzylation-orthoester rearrangement approach.
A simple one-pot method is reported for making partially protected glycosyl acceptors from O-methyl or S-alkyl/aryl glycosides of D-glucose, D-galactose, D-arabinose, L-rhamnose, L-fucose and lactose via orthoester formation, benzylation and selective hydrolysis.
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002845:Chromatography; D004187:Disaccharides / Q000138:chemical synthesis*; D006027:Glycosides / Q000138:chemical synthesis*; D008969:Molecular Sequence Data; D009005:Monosaccharides / Q000138:chemical synthesis*
D004187:Disaccharides; D006027:Glycosides; D009005:Monosaccharides