title: Endovascular GDC-mediated flow-reversal for complex posterior circulation saccular aneurysms. A report of two cases and critical appraisal.
abstract: Two patients with giant complex saccular aneurysms of the proximal basilar artery were managed with flow-reversal using the endovascular route. Complete obliteration of the aneurysm was successful in one patient resulting in long term survival (8 year follow-up completed). Incomplete obliteration of the aneurysm persisted in the other patient, resulting in recurrence and a fatal haemorrhage one year after treatment. Endovascular flow-reversal is a good treatment option for these lesions with a high surgical risk. However, persistent incomplete thrombosis of these aneurysms following flow-reversal should lead to the consideration of alternate treatment strategies.
mesh_terms: D000328:Adult; D000368:Aged; D001488:Basilar Artery; D004621:Embolization, Therapeutic / Q000379:methods*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery*; D008297:Male; D012008:Recurrence; D012039:Regional Blood Flow; D013345:Subarachnoid Hemorrhage / Q000209:etiology*; D016019:Survival Analysis; D013927:Thrombosis; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000379:methods*