Photo-regulation of DNA function by azobenzene-tethered oligonucleotides.
Multiple azobenzene moieties were tethered to DNA on D-threoninol linker, and formation and dissociation of DNA duplex could be reversibly photo-regulated either by irradiating UV or visible light. With this photo-responsive DNA, RNase H reaction was also successfully photo-regulated.
D001391:Azo Compounds / Q000737:chemistry*; D020029:Base Pairing; D004247:DNA / Q000737:chemistry*; D008027:Light; D009841:Oligonucleotides / Q000737:chemistry*; D010777:Photochemistry; D016914:Ribonuclease H / Q000378:metabolism; D014466:Ultraviolet Rays
D001391:Azo Compounds; D009841:Oligonucleotides; D004247:DNA; D016914:Ribonuclease H; C009850:azobenzene