Synthesis of thymine derivatives of 4-hydroxyvaline.
A synthetic route to thymine derivatives of (2S,3R)- and (2S,3S)-4-hydroxyvaline has been developed starting from commercially available L-aspartic acid.
Abraham
Achamma
A
Chemistry, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, UK.
Howarth
Nicola M
NM
D001224:Aspartic Acid; D004247:DNA / Q000737:chemistry; D006909:Hydroxyproline / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D013941:Thymine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
D007202:Indicators and Reagents; D001224:Aspartic Acid; D004247:DNA; D013941:Thymine; D006909:Hydroxyproline