xylo-configured oligonucleotides (XNA, xylo nucleic acids): synthesis and hybridization studies.
We report synthesis and high-affinity hybridization of fully modified home-thymine 2'-deoxy and 2'-deoxy-2'-fluoro xylo nucleic acids.
Poopeiko
Nicolai E
NE
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
Dahl
Britta M
BM
Wengel
Jesper
J
D001483:Base Sequence; D018076:DNA, Complementary / Q000737:chemistry; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D018075:RNA, Complementary / Q000737:chemistry; D013941:Thymine; D014994:Xylose
D018076:DNA, Complementary; D009841:Oligonucleotides; D018075:RNA, Complementary; D014994:Xylose; D013941:Thymine