[Acute renal failure secondary to hepatic veno-occlusive disease in a bone marrow transplant patient].
Acute renal failure following bone marrow transplantation is a frequent complication with an incidence ranging 15-30% and with high rates of morbidity and mortality. Numerous potential etiologies can be implicated as chemotherapy regimen, use of nephrotoxic antibiotics, sepsis-induced damage, cyclosporine toxicity and other especific pathologies as graft-v-host disease or veno-occlusive disease of the liver. We report the case of a 41-year-old man who underwent autologous peripheral blood stem cell transplantation and developed and acute renal failure secondary to a fatal veno-occlusive disease of the liver. Incidence, potential predisposing factors, outcome and possibilities of treatment are reviewed.
Borrego
F J
FJ
Servicio de Nefrología, Complejo Hospitalario de Jaén, Hospital Universitario Médico-Quirúrgico.
Viedma
G
G
Pérez del Barrio
P
P
Gil
J M
JM
de Santis-Scoccia
C
C
Ramírez Huerta
J M
JM
Alcalá
A
A
Pérez Bañasco
V
V
D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D017809:Fatal Outcome; D006504:Hepatic Veno-Occlusive Disease / Q000150:complications* / Q000628:therapy; D006801:Humans; D008111:Liver Function Tests; D008297:Male