title: Stereocontrolled synthesis of diene and enyne sugar-modified nucleosides and their interaction with S-adenosyl-L-homocysteine hydrolase.
abstract: Conjugated diene 5-7 and enyne 8 analogs derived from adenosine and uridine were synthesized employing Pd-catalyzed cross-coupling reactions.
authors.affiliation: Department of Chemistry, Florida International University, Miami, Florida 33199, USA. wnuk@fiu.edu
authors.forename: Stanislaw F
authors.initials: SF
authors.lastname: Wnuk
authors.forename: Pablo R
authors.initials: PR
authors.lastname: Sacasa
authors.forename: Leigh N
authors.initials: LN
authors.lastname: Crain
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Lewandowska
authors.forename: Jinsong
authors.initials: J
authors.lastname: Zhang
authors.forename: Ronald T
authors.initials: RT
authors.lastname: Borchardt
mesh_terms: D043383:Adenosylhomocysteinase / Q000378:metabolism*; D007202:Indicators and Reagents; D007700:Kinetics; D009243:NAD / Q000378:metabolism; D009705:Nucleosides / Q000138:chemical synthesis* / Q000378:metabolism*; D013379:Substrate Specificity
chemical_list: D007202:Indicators and Reagents; D009705:Nucleosides; D009243:NAD; D043383:Adenosylhomocysteinase