Reduction of noise-stress-induced physiological damage by radices of Astragali and Rhodiolae: glycogen, lactic acid and cholesterol contents in liver of the rat.
Noise is one of the factors that induces critical stress in animals. The contents of glycogen, lactic acid and cholesterol in the liver of noise-stressed rats were analyzed in order to investigate the alleviation of noise-stress-induced physiological damages by traditional medicine using Astragali and Rhodiolae radices. More than 95 dB noise ranging from 2 to 4 kHz reduced the contents of these compounds in the liver of rats not injected with the extract of Astragali or Rhodiolae, but did not change the contents in the liver of rats injected with the Astragali or Rhodiolae extract. These results show that noise induced stress in the rats via a decrease in contents of these compounds in the liver and that Astragali or Rhodiolae maintained the contents of these compounds in the liver of the noise-stressed rats. The results indicate that Astragali or Rhodiolae improved the ability for rats to resist noise stress.
Zhu
Bei-Wei
BW
College of Bio & Food Technology, Dalian Institute of Light Industry, China.
Sun
Yu-Mei
YM
Yun
Xia
X
Han
Song
S
Piao
Mei-Lan
ML
Murata
Yoshiyuki
Y
Tada
Mikiro
M
D000818:Animals; D027883:Astragalus Plant / Q000737:chemistry*; D002784:Cholesterol / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D019344:Lactic Acid / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism*; D009622:Noise / Q000009:adverse effects*; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D029771:Rhodiola / Q000737:chemistry*; D013312:Stress, Physiological / Q000378:metabolism*
D004365:Drugs, Chinese Herbal; D008112:Liver Glycogen; D010936:Plant Extracts; D019344:Lactic Acid; D002784:Cholesterol