title: Synthesis of [1'-fluoro-2',2'-bis-(hydroxymethyl)cyclopropylmethyl]purines as antiviral agents.
abstract: [1'-Fluoro-2',2'-bis-(hydroxymethyl)cyclopropylmethyl]purines were designed, synthesized and their antiviral activity against poliovirus, HSV and HIV was evaluated.
authors.affiliation: College of Pharmacy, Sookmyung Women's University, Yongsangu, Seoul, Korea.
authors.forename: Ju-Hyun
authors.initials: JH
authors.lastname: Park
authors.forename: Myung-Hee
authors.initials: MH
authors.lastname: Choi
authors.forename: Lak Shin
authors.initials: LS
authors.lastname: Jeong
authors.forename: Moon Woo
authors.initials: MW
authors.lastname: Chun
authors.forename: Hee-Doo
authors.initials: HD
authors.lastname: Kim
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D003521:Cyclopropanes / Q000737:chemistry / Q000494:pharmacology; D006678:HIV / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects; D018258:Herpesvirus 2, Human / Q000187:drug effects; D015394:Molecular Structure; D017955:Poliovirus / Q000187:drug effects; D011687:Purines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000998:Antiviral Agents; D003521:Cyclopropanes; D011687:Purines