["Quorum sensing" or social behavior of bacteria].
The review deals with the data of literature on the role of the "quorum sensing" (QS) system ensuring the social behavior of bacteria in the regulation of virulence genes. The mechanisms of the action of these systems in Gram-negative and Gram-positive bacteria, as well as the influence of acyl-homoserine lactones, one of the components of the QS system, on the immune response of the infected host are discussed. In addition, in this review the data of literature on the existence of bacteria in the form of biofilms are presented. The methods of the identification of biofilms, the methods of their experimental preparation and the role of the QS system in the process of their formation are considered.
Gintsburg
A L
AL
Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
Il'ina
T S
TS
Romanova
Iu M
IuM
D001419:Bacteria / Q000235:genetics* / Q000472:pathogenicity*; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D018441:Biofilms; D015964:Gene Expression Regulation, Bacterial; D006714:Homoserine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000502:physiology; D007783:Lactones / Q000737:chemistry; D015398:Signal Transduction; D012919:Social Behavior; D014774:Virulence / Q000235:genetics*
D001426:Bacterial Proteins; D007783:Lactones; D006714:Homoserine