Successful outcome of disseminated Fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia.
A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.
Durand-Joly
Isabelle
I
Parasitologie-Mycologie, Faculté de Médecine, CHRU de Lille, Lille, France. i-joly@chru-lille.fr
Alfandari
Serge
S
Benchikh
Zinnédine
Z
Rodrigue
Marion
M
Espinel-Ingroff
Ana
A
Catteau
Benoit
B
Cordevant
Christophe
C
Camus
Daniel
D
Dei-Cas
Eduardo
E
Bauters
Francis
F
Delhaes
Laurence
L
De Botton
Stéphane
S
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D002051:Burkitt Lymphoma / Q000150:complications*; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology; D004359:Drug Therapy, Combination; D005260:Female; D005670:Fusarium / Q000187:drug effects*; D006801:Humans; D011743:Pyrimidines / Q000627:therapeutic use*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D065819:Voriconazole