title: [Plasma amino acids profile of healthy pregnant adolescents in Maracaibo, Venezuela].
abstract: One hundred female adolescents (13-18 y) were clinical and anthropometrically studied to select only those with adequate nutrition. Most adolescents belonged to IV socio-economic stratum families (worker class). Height, weight, age, body mass index and medial arm circumference were used as anthropometric parameters. After screening, only 41 non pregnant girls (control) and 42 pregnant girls with adequate nutrition were selected to analyze plasma amino acids. Fasting peripheral venous blood was drawn, and plasma amino acids were analyzed by HPLC. Amino acid concentrations were expressed as umol/L +/- SE. SAS/STAT program was used for statistical analysis. Amino acid values of control adolescent group were found in ranges reported by other investigators, with slight variations, mostly in diminution, presumably due to nutritional, metabolic or genetic conditions of people living in tropical regions. In pregnant healthy adolescents, distributed according to gestational age: < 32 weeks (n = 30) and > 32 weeks (n = 12), a diminution of total molar plasma amino acids was found, by comparing with control values. Ten amino acids (Pro, Gly, Gln, Arg, Ser, Orn, Tau, Leu, Thr and Val) appeared significantively diminished throughout gestation, being Gly. Gln and Arg most affected since earlier weeks. During the 2nd period. Thr and Val increased their grade of affectation; whereas some amino acids values (Orn, Pro and Tau) tended to recuperate. Several of affected amino acids are gluconegoenic, thus, they could be utilized to supply the energy required by the pregnant adolescent against her double stress: the fetus development and her own development. The plasma amino acid values reported in both, healthy non pregnant and pregnant adolescents, could be taken as regional referential profile of plasma amino acids in this poblational group for further research on adolescent and fetal--maternal malnutrition.
authors.affiliation: Laboratorio de Investigación en Desnutrición Infantil, Instituto de Investigaciones Biológicas, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
authors.forename: Pablo
authors.initials: P
authors.lastname: Ortega
authors.forename: Haydée V
authors.initials: HV
authors.lastname: Castejón
authors.forename: María G
authors.initials: MG
authors.lastname: Argotte
authors.forename: Gisela
authors.initials: G
authors.lastname: Gómez
authors.forename: Lissette
authors.initials: L
authors.lastname: Bohorquez
authors.forename: Jesús R
authors.initials: JR
authors.lastname: Urrieta
mesh_terms: D000293:Adolescent; D000596:Amino Acids / Q000097:blood*; D000886:Anthropometry; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D009752:Nutritional Status; D011247:Pregnancy; D011253:Pregnancy in Adolescence / Q000097:blood*; D014687:Venezuela
chemical_list: D000596:Amino Acids