[[F-18]-fluorodeoxyglucose (FDG) positron emission tomography (PET) as a diagnostic for hip endoprosthesis loosening].
OBJECTIVE
The purpose of this study was to examine the FDG-PET in respect of its diagnostic valency with regard to septic/aseptic loosening of lower limb prostheses.


METHODS
28 patients with 41 lower limb prostheses were examined by means of FDG-PET to evaluate septic/aseptic loosening of their hip prostheses. Therefore, a differentiated FDG-PET result interpretation subdivided into five categories was developed. The final diagnosis was based on operative findings with following culture and histological outcome.


RESULTS
The worked-out categories showed a high agreement to the intraoperative macroscopic and histological results (n = 23 correctly positive, n = 1 false positive, n = 1 correctly negative and n = 3 false negative).


CONCLUSIONS
With a subtly differentiated interpretation (categories I - V) of the qualitative glucose metabolism safe statements can be made regarding septic/aseptic endoprostheses loosening. This was impressively confirmed by the agreement of the FDG results with the histological results.
Mumme
T
T
Orthopädische Klinik, Universitätsklinikum Aachen. Torsten.Mumme@gmx.de
Reinartz
P
P
Cremerius
U
U
Hermanns
B
B
Müller-Rath
R
R
Neuss
M
M
Büll
U
U
Wirtz
D C
DC
D000368:Aged; D000369:Aged, 80 and over; D019544:Equipment Failure Analysis / Q000379:methods*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D016896:Treatment Outcome
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18