Similarities and differences in motion processing between the human and macaque brain: evidence from fMRI.
The present report reviews a series of functional magnetic resonance imaging (fMRI) activation studies conducted in parallel in awake monkeys and humans using the same motion stimuli in both species. These studies reveal that motion stimuli engage largely similar cortical regions in the two species. These common regions include MT/V5 and its satellites, of which FST contributes more to the human motion complex than is generally assumed in human imaging. These results also establish a direct link between selectivity of MT/V5 neurons for speed gradients and functional activation of human MT/V5 by three-dimensional (3D) structure from motion stimuli. On the other hand, striking functional differences also emerged: in humans V3A and several regions in the intraparietal sulcus (IPS) are much more motion sensitive than their simian counterparts.
Orban
Guy A
GA
K.U. Leuven, Laboratorium voor Neuro- en Pyschofysiologie, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
Fize
Denis
D
Peuskens
Hendrik
H
Denys
Katrien
K
Nelissen
Koen
K
Sunaert
Stefan
S
Todd
James
J
Vanduffel
Wim
W
D000328:Adult; D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology*; D001931:Brain Mapping; D005133:Eye Movements; D005260:Female; D007839:Functional Laterality; D000882:Haplorhini; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009038:Motion; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation; D013045:Species Specificity; D014795:Visual Pathways; D014851:Wakefulness