title: Serum concentrations of pneumococcal anticapsular antibodies in children with pneumonia associated with Streptococcus pneumonia infection.
abstract: The levels of specific IgG antibody to pneumococcal capsular polysaccharides were investigated in 182 children, aged 2-5 years, who were hospitalized for community-acquired pneumonia, including 55 (30.2%) with evidence of acute pneumococcal infection. Results show that children with concentrations of specific IgG antibody that would protect against invasive disease do not seem to be protected against pneumonia associated with pneumococcal infection.
authors.affiliation: Pediatric Department I, University of Milan, Italy.
authors.forename: Susanna
authors.initials: S
authors.lastname: Esposito
authors.forename: Roberta
authors.initials: R
authors.lastname: Droghetti
authors.forename: Nadia
authors.initials: N
authors.lastname: Faelli
authors.forename: Annalisa
authors.initials: A
authors.lastname: Lastrico
authors.forename: Claudia
authors.initials: C
authors.lastname: Tagliabue
authors.forename: Laura
authors.initials: L
authors.lastname: Cesati
authors.forename: Ciro
authors.initials: C
authors.lastname: Bianchi
authors.forename: Nicola
authors.initials: N
authors.lastname: Principi
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D016667:Bacterial Capsules / Q000276:immunology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D011008:Pneumococcal Infections / Q000097:blood / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000276:immunology; D013296:Streptococcus pneumoniae / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D011135:Polysaccharides, Bacterial