title: Left-sided endocarditis caused by Pseudomonas aeruginosa: successful treatment with meropenem and tobramycin.
abstract: Medical treatment alone is rarely successful in left-sided infective endocarditis caused by Pseudomonas aeruginosa. We report the cure of such a case with high-dose meropenem in combination with tobramycin.
authors.affiliation: Departments of Laboratory Medicine and Pathology, Evanston Northwestern Healthcare, Evanston and Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. pgavin@enh.org
authors.forename: P J
authors.initials: PJ
authors.lastname: Gavin
authors.forename: M T
authors.initials: MT
authors.lastname: Suseno
authors.forename: F V
authors.initials: FV
authors.lastname: Cook
authors.forename: L R
authors.initials: LR
authors.lastname: Peterson
authors.forename: R B
authors.initials: RB
authors.lastname: Thomson
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008297:Male; D000077731:Meropenem; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013845:Thienamycins / Q000627:therapeutic use*; D014031:Tobramycin / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem; D014031:Tobramycin