Efficacy and impact of monophasic versus biphasic countershocks for transthoracic cardioversion of persistent atrial fibrillation.
This report compares the cumulative efficacy of cardioversion and skeletal muscle injury after either damped sine wave monophasic or truncated exponential biphasic transthoracic cardioversion of persistent atrial fibrillation. The trial sought to refute the null hypothesis of therapeutic equivalence between monophasic and biphasic waveforms. Results of the study reveal similar cumulative efficacy of waveforms and greater levels of skeletal muscle damage when patients are younger and male, and when monophasic waveforms are used.
Marinsek
Matej
M
Department of Cardiology, Celje General Hospital, Celje, Slovenia. mmarinsek@hotmail.com
Larkin
Gregory Luke
GL
Zohar
Petra
P
Bervar
Mojca
M
Pekolj-Bicanic
Mojca
M
Mocnik
Franciska Skrabl
FS
Noc
Marko
M
Podbregar
Matej
M
D000367:Age Factors; D000368:Aged; D001281:Atrial Fibrillation / Q000628:therapy*; D001835:Body Weight; D003402:Creatine Kinase / Q000097:blood*; D004554:Electric Countershock / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D018482:Muscle, Skeletal / Q000293:injuries* / Q000378:metabolism*; D009211:Myoglobin / Q000378:metabolism*; D011237:Predictive Value of Tests; D012737:Sex Factors
D009211:Myoglobin; D003402:Creatine Kinase