title: Incidence and mechanism of late stent malapposition after phosphorus-32 radioactive stent implantation.
abstract: Late stent malapposition is a potential complication of intracoronary brachytherapy. The aim of our study was to determine the incidence and mechanism of late stent malapposition after implantation of phosphorus-32 radioactive stents. We analyzed 159 patients for de novo lesions after the implantation of phosphorus-32 radioactive stents. There were 15 late stent malappositions. The incidence of malapposition was higher in patients who received Hot-Ends Isostents. External elastic membrane expansion greater than plaque increase in malapposed segments was observed. Late stent malapposition is caused by a localized increase in external elastic membrane that is greater than the increase in plaque area; this is believed to be a dose-dependent phenomenon because it was more common with Hot-Ends Isostents.
authors.affiliation: Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Kalinczuk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Pregowski
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Christian E
authors.initials: CE
authors.lastname: Dilcher
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kotani
authors.forename: Mariusz
authors.initials: M
authors.lastname: Kruk
authors.forename: Vivek M
authors.initials: VM
authors.lastname: Shah
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Canos
authors.forename: Rosana C
authors.initials: RC
authors.lastname: Chan
authors.forename: Neil J
authors.initials: NJ
authors.lastname: Weissman
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects* / Q000379:methods; D003327:Coronary Disease / Q000532:radiotherapy*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004307:Dose-Response Relationship, Radiation; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use*; D015607:Stents / Q000009:adverse effects*; D018084:Ultrasonography, Interventional
chemical_list: D010761:Phosphorus Radioisotopes