title: [A case of primary lung cancer in a young female with tongue cancer].
abstract: We describe a case of lung tumor in a 33-year-old woman with tongue cancer. She had noticed a painful sensation in her tongue in April 2000. The results of a physical examination showed a 22 x 11 mm ulcerated lesion on the right side of her tongue. A biopsy specimen showed a moderately differentiated squamous cell carcinoma. A preoperative chest radiograph showed no evidence of pulmonary metastasis. No neck lymphadenopathy was found. The tongue cancer was resected in September 2000, and the pathological stage was T2 N0 M0. A solitary pulmonary lesion appeared 8 months after the surgery. A Histological examination of a transbronchial lung biopsy specimen showed a moderately differentiated squamous cell carcinoma. It was difficult to distinguish histopathologically or immunohistochemically between a second primary tumor and a metastasis, but the pulmonary lesion was considered to be a second primary tumor on the basis of a single endobronchial lesion that appeared after the T2 tongue cancer with no regional recurrence or cervical lymphadenopathy. Treatment with chemotherapy and irradiation was not effective and the patient died 3 months after the diagnosis of lung cancer.
authors.affiliation: Department of Internal Medicine, Tokyo Dental College, Ichikawa General Hospital, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kawada
authors.forename: Takeshi
authors.initials: T
authors.lastname: Terashima
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Morishita
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Kasahara
authors.forename: Yasuasa
authors.initials: Y
authors.lastname: Yajima
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Noma
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014062:Tongue Neoplasms / Q000601:surgery*