[Comparative evaluation of the antioxidant and antiatherogenic effect of natural and selenoorganic substances].
The antioxidant and atherogenic effects of naturally occurring compounds (soya isoflavones) and of the synthetic organic compounds of selenium (selenopyran and dimethyl-pyrosalyl-selenide) on the primary cell culture of human aortic subendothelial intima and on macrophage cell culture were investigated. Our results suggest that soya isoflavones exhibit mainly antiatherogenic effect and organic compounds of selenium exhibit mainly antioxidant effect.
Khachaturova
V P
VP
Institute of Nutrition, RAMS, Ustinsky proezd, 2/14, 109240, Moscow.
Suprun
I V
IV
Vasil'ev
A V
AV
D000975:Antioxidants / Q000494:pharmacology*; D001161:Arteriosclerosis / Q000517:prevention & control*; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects; D006801:Humans; D007529:Isoflavones / Q000494:pharmacology*; D008264:Macrophages / Q000166:cytology / Q000187:drug effects; D016566:Organoselenium Compounds / Q000494:pharmacology*
D000975:Antioxidants; D007529:Isoflavones; D016566:Organoselenium Compounds