title: Myocardial infarction in patients with diabetes. Results of primary coronary angioplasty.
abstract: BACKGROUND
  Although the introduction of primary percutaneous coronary interventions (PCI) improved the outcome of patients with acute myocardial infarction (MI), diabetes remains a significant factor which worsens prognosis.
  
  
  OBJECTIVE
  To compare the immediate and in-hospital results of PCI in patients with acute MI with or without diabetes.
  
  
  METHODS
  The outcome of 139 patients with diabetes and 528 patients without diabetes was compared. Thrombolytic therapy was administered prior to PCI to 43.2% of patients with diabetes and 42.4% of patients without diabetes.
  
  
  RESULTS
  Patients with diabetes were older, more frequently of female gender and had higher incidence of hypertension as well as multi-vessel coronary artery disease. PCI was effective in 85.6% of diabetics and 90.2% of non-diabetic patients (NS). The reocclusion rate was significantly higher in diabetics than in non-diabetics (11.5% vs 5.5%, p=0.012) whereas the incidence of haemorrhagic complications was similar. Mortality rates were comparable in both groups (7.2% in diabetics vs 5.9% in non-diabetics, NS).
  
  
  CONCLUSIONS
  1) Immediate efficacy of primary PCI for acute MI is similar in diabetics and non-diabetics, however, the in-hospital reocclusion rate is higher in the former group of patients. 2) In-hospital mortality is not affected by the presence of diabetes. 3) Thrombolytic and invasive treatment of diabetic patients with acute MI is not associated with an increased risk of bleeding.
authors.affiliation: III Chair and Department of Cardiology, Silesian Medical Academy, Silesian Center for Heart Diseases, Zabrze, Poland.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Gasior
authors.forename: Jarosław
authors.initials: J
authors.lastname: Wasilewski
authors.forename: Marek
authors.initials: M
authors.lastname: Gierlotka
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Zebik
authors.forename: Andrzej
authors.initials: A
authors.lastname: Lekston
authors.forename: Rafał
authors.initials: R
authors.lastname: Wojnar
authors.forename: Marek
authors.initials: M
authors.lastname: Kondys
authors.forename: Janusz
authors.initials: J
authors.lastname: Szkodziński
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Wilczek
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wnek
authors.forename: Jacek
authors.initials: J
authors.lastname: Piegza
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Dyrbuś
authors.forename: Michał
authors.initials: M
authors.lastname: Hawranek
authors.forename: Bozena
authors.initials: B
authors.lastname: Szyguła-Jurkiewicz
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Honisz
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Kalarus
authors.forename: Lech
authors.initials: L
authors.lastname: Poloński
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D012720:Severity of Illness Index; D016896:Treatment Outcome