Biokinetics and assessment of intake of thorium dioxide.
The aim of this work was to investigate the biokinetics of thorium dioxide in animals for the purpose of assessing intakes of the compound by workers and the resulting doses. The results imply that measurements of the decay products in the chest or extrapolations from urine analysis data are unlikely to be of value for doses below 20 mSv. Even higher doses should be interpreted with caution as a consequence of uncertainties in particle size distribution and variations in dietary excretion.
Hodgson
S A
SA
National Radiological Protection Board, Chilton, Didcot, Oxon OX11 0RQ, UK. sue.hodgson@nrpb.org
Stradling
G N
GN
Hodgson
A
A
Smith
T J
TJ
Youngman
M J
MJ
Ansoborlo
E
E
D000042:Absorption; D000280:Administration, Inhalation; D000396:Air Pollutants, Radioactive / Q000032:analysis; D000818:Animals; D018893:Bronchoalveolar Lavage; D003198:Computer Simulation; D005260:Female; D006801:Humans; D019570:Inhalation Exposure / Q000032:analysis; D007275:Injections, Intravenous; D008168:Lung / Q000378:metabolism*; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D016273:Occupational Exposure / Q000032:analysis; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D051381:Rats; D012137:Respiratory System / Q000378:metabolism; D013909:Thorax / Q000378:metabolism; D013911:Thorium Dioxide / Q000008:administration & dosage / Q000032:analysis* / Q000493:pharmacokinetics*; D016482:Urinalysis
D000396:Air Pollutants, Radioactive; D013911:Thorium Dioxide