Efficacy of enamel matrix protein applied to spontaneous periodontal disease in two dogs.
Enamel matrix protein (EMP) was applied for regeneration of periodontal tissue in 2 dogs with spontaneous periodontal disease. Case 1 had bony resorption around the root and root apex of the maxillary fourth premolars. Case 2 had vertical resorption of bone between the mandibular first and second molars. A flap was formed in the buccal gingiva, and EMP was applied onto the surface of the exposed root. One or 4 months postoperatively, increased bone level and clinical attachment were recognized. EMP was therefore suggested to be effective to induce regeneration of periodontal tissues in the cases with periodontal disease.
Watanabe
Kazuhiro
K
Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Kikuchi
Masahiro
M
Okumura
Masahiro
M
Kadosawa
Tsuyoshi
T
Fujinaga
Toru
T
D000818:Animals; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D004285:Dogs; D005260:Female; D008297:Male; D010510:Periodontal Diseases / Q000000981:diagnostic imaging / Q000628:therapy / Q000662:veterinary*; D011859:Radiography; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins