Assessment of immunoglobulin M enzyme immunoassays for diagnosis of measles.
We evaluated the performance of three commercial measles immunoglobulin M enzyme immunoassays from Meddens, Denka Seiken, and Behring. The sensitivities were determined to be 96.7% for the Meddens and Denka Seiken assays and 87.9% for the Behring assay. The specificities of the assays were determined to be 94.6% for Meddens, 98.2% for Denka Seiken, and 98.7% for Behring.
Tipples
Graham A
GA
National Microbiology Laboratory, Health Canada, Winnipeg, Manitoba, Canada. graham_tipples@hc-cs.gc.ca
Hamkar
Rasool
R
Mohktari-Azad
Talat
T
Gray
Michael
M
Parkyn
Geoff
G
Head
Carol
C
Ratnam
Samuel
S
D000914:Antibodies, Viral / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000097:blood*; D008457:Measles / Q000175:diagnosis*; D008459:Measles virus / Q000276:immunology*; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
D000914:Antibodies, Viral; D007075:Immunoglobulin M; D011933:Reagent Kits, Diagnostic