Postmenopausal bleeding: squamous cell carcinoma of cervix with coexisting endometrial tuberculosis.
METHODS
A case of squamous cell carcinoma of cervix co-existent with endometrial tuberculosis presenting as postmenopausal bleeding is being reported for its rarity. The atrophic postmenopausal endometrium is thought to be poorly supportive of tubercle bacilli. Following a radical Wertheim's hysterectomy patient had a hectic postoperative period, which responded to antitubercular treatment. Diagnosis of tuberculosis in this case was made on histopathology postoperatively and confirmed by polymerase chain reaction (PCR) on scrapes from the granulomas obtained by microdissection.


CONCLUSIONS
Tuberculosis complicating malignant disease may occur in regions with a high prevalence of disease; with a resurgence of tuberculosis worldwide this association may not be uncommon. The diagnosis and treatment of tuberculosis in a patient with cancer assumes importance as a high mortality has been seen in patients with co-existent disease.
Rajaram
Shalini
S
Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, 110095 Shahdara, Delhi, India. shalini_rajaram@rediffmail.com
Dev
Geeta
G
Panikar
Nirupma
N
Singh
Kishor Chandra
KC
Goel
Neerja
N
D000995:Antitubercular Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D014384:Tuberculosis, Female Genital / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014592:Uterine Hemorrhage / Q000209:etiology
D000995:Antitubercular Agents