Evaluation of colloid size for sentinel nodes detection using radioisotope in early gastric cancer.
The purpose of this study was to investigate the relationship between colloid size and the detection of sentinel nodes (SN) in early gastric cancer. Three size of 99mTechnetium-tin colloids (500, 100 and 50 nm) were preoperatively injected into the submucosa under endoscopic control. Lymph node metastasis and micrometastasis was examined. RI-uptake in the hottest nodes and the total RI-uptake in the hot nodes were highest in the size of 100 nm. At least one lymph node metastasis, including micrometastasis, was included in the hot nodes. RI-labeled colloid size was one of the important factors to detect SN in early gastric cancer.
Uenosono
Yoshikazu
Y
First Department of Surgery, Kagoshima University School of Medicine, 8-35-1 Sakuragaoka, 890-8520, Kagoshima, Japan. uenosono@m3.kufm.kagoshima-u.ac.jp
Natsugoe
Shoji
S
Higashi
Hiroshi
H
Ehi
Katsuhiko
K
Miyazono
Futoshi
F
Ishigami
Sumiya
S
Hokita
Shuichi
S
Aikou
Takashi
T
D000328:Adult; D000368:Aged; D003102:Colloids; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology; D013671:Technetium Tc 99m Sulfur Colloid
D003102:Colloids; D013671:Technetium Tc 99m Sulfur Colloid