Malignant hypertension and cerebral haemorrhage in Seckel syndrome.
Seckel syndrome is an autosomal recessive condition with severe short stature and facial and neurological anomalies. Intracranial haemorrhage, due to rupture of a cerebral aneurysm, is a very rare complication of this syndrome. Malignant hypertension may play an important role in the aetiology of the aneurysm and early detection is essential in order to prevent organ damage.


CONCLUSIONS
we report a new case of Seckel syndrome associated with malignant hypertension and cerebral haemorrhage.
Di Bartolomeo
Rossella
R
Institute of Paediatrics, Policlinico A. Gemelli, Largo Gemelli 1, 00168, Rome, Italy. lelladibi@yahoo.com
Polidori
Giancarlo
G
Piastra
Marco
M
Viola
Luigi
L
Zampino
Guiseppe
G
Chiaretti
Antonio
A
D000015:Abnormalities, Multiple; D017542:Aneurysm, Ruptured / Q000209:etiology; D002543:Cerebral Hemorrhage / Q000209:etiology*; D002648:Child; D004392:Dwarfism / Q000150:complications*; D006801:Humans; D006974:Hypertension, Malignant / Q000209:etiology*; D002532:Intracranial Aneurysm / Q000209:etiology; D008297:Male; D008831:Microcephaly / Q000150:complications*; D013577:Syndrome