Hirschprung's disease and imperforate anus in Pallister-Hall syndrome: a new association.
Hirschprung's disease and imperforate anus are described concurrently in a newborn with Pallister-Hall syndrome as well as the difficulties in making this diagnosis. Awareness of this new association should prompt the exclusion of Hirschprung's disease before repair of imperforate anus in infants with Pallister-Hall syndrome. The known genetic parallels between these conditions is discussed briefly in terms of etiology.
Haynes
Jeffrey H
JH
Division of Pediatric Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0015, USA.
Bagwell
Charles E
CE
D000015:Abnormalities, Multiple / Q000235:genetics; D001006:Anus, Imperforate / Q000150:complications*; D002897:Chromosomes, Human, Pair 7; D053823:Hedgehog Proteins; D006627:Hirschsprung Disease / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013577:Syndrome; D015534:Trans-Activators
D053823:Hedgehog Proteins; D015534:Trans-Activators