title: [Diagnosis of Helicobacter pylori infection with urine and stool].
abstract: OBJECTIVE
  The urine antibody and stool antigen test are newly developed non-invasive tests for Helicobacter pylori (H. pylori) infection. The aim of this study was to assess the diagnostic value of these tests.
  
  
  METHODS
  Urine and stool specimens from 50 consecutive patients who had undergone gastroscopy (28 men, mean age 54 years) were obtained. A kit for antibody against H. pylori (RAPIRUN test) was used for urine specimens and a kit for H. pylori antigen using ELISA (HpSA test) was used for stool specimens. None of patients had ever received any treatment to eradicate H. pylori. The H. pylori status was evaluated based on three different tests (histology, 13C-urea breath test, rapid urease test) and defined as positive when two of three tests were positive.
  
  
  RESULTS
  Of 50 patients, 31 patients were diagnosed as H. pylori positive and 15 patients were negative. The RAPIRUN test was positive in 24 of 31 patients (sensitivity 77.4%) and negative in 13 of 15 patients (specificity 86.7%). The HpSA test was positive in 25 of 31 patients (sensitivity 80.1%) and negative in 14 of 15 patients (specificity 93.3%).
  
  
  CONCLUSIONS
  The accuracies of H. pylori urine antibody and stool antigen test are similar to those of Western studies. These two tests are found to be useful methods for diagnosis of H. pylori infection in Korea.
authors.affiliation: Department of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea. yugina@chollian.net
authors.forename: Young Hak
authors.initials: YH
authors.lastname: Lee
authors.forename: Seung Yup
authors.initials: SY
authors.lastname: Lee
authors.forename: Young Tak
authors.initials: YT
authors.lastname: Kim
authors.forename: Chang Keun
authors.initials: CK
authors.lastname: Park
authors.forename: Chang Min
authors.initials: CM
authors.lastname: Jo
authors.forename: Won Young
authors.initials: WY
authors.lastname: Tak
authors.forename: Young Oh
authors.initials: YO
authors.lastname: Kweon
authors.forename: Sung Kook
authors.initials: SK
authors.lastname: Kim
authors.forename: Yong Hwan
authors.initials: YH
authors.lastname: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000652:urine*; D000942:Antigens, Bacterial / Q000032:analysis*; D005243:Feces / Q000382:microbiology*; D005260:Female; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013272:Stomach Diseases / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic