Cyclodextrins and emulsions.
This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents.
Duchêne
Dominique
D
UMR CNRS 8612, Physico-chimie, Pharmacotechnie, Biopharmacie, Faculté de Pharmacie, Université Paris-Sud, 5, Rue Jean Baptiste Clément, 92290 Châtenay Malabry, France. dominique.duchene@cep.u-psud.fr
Bochot
Amélie
A
Yu
Shan-Chen
SC
Pépin
Céline
C
Seiller
Monique
M
D000818:Animals; D002626:Chemistry, Pharmaceutical; D003505:Cyclodextrins / Q000737:chemistry / Q000378:metabolism*; D004655:Emulsions / Q000737:chemistry / Q000378:metabolism*; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism; D006801:Humans
D003505:Cyclodextrins; D004655:Emulsions; D005227:Fatty Acids