[Study of pharmacological properties of betulin bishemiphthalate].
The results of pharmacological tests showed that betulin bishemiphthalate possesses hepatoprotector, antioxidant, and immunotropic properties. Administered in combination with hydroxymethyluracil, that betulin bishemiphthalate prevented the loss of experimental animals upon irradiation.
Karachurina
L T
LT
Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054 Russia.
Sapozhnikova
T A
TA
Zarudiĭ
F S
FS
Flekhter
O B
OB
Nigmatullina
L R
LR
Galin
F Z
FZ
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000633:toxicity; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000975:Antioxidants / Q000494:pharmacology* / Q000633:toxicity; D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control; D007111:Immunity, Cellular / Q000187:drug effects; D007928:Lethal Dose 50; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D051379:Mice; D010795:Phthalic Acids / Q000494:pharmacology* / Q000633:toxicity; D011832:Radiation Injuries / Q000401:mortality / Q000517:prevention & control; D011837:Radiation-Protective Agents / Q000494:pharmacology* / Q000633:toxicity; D023382:Toxicity Tests, Acute; D014315:Triterpenes / Q000494:pharmacology* / Q000633:toxicity; D000094062:Betulinic Acid
D000276:Adjuvants, Immunologic; D000975:Antioxidants; D010795:Phthalic Acids; D011837:Radiation-Protective Agents; D014315:Triterpenes; C479883:betulin bishemiphthalate; D000094062:Betulinic Acid