title: Review of respiratory morbidity from occupational exposure to oil mists.
abstract: The American Conference of Governmental Industrial Hygienists (ACGIH) has recommended that the threshold limit value (TLV) for mineral oil mists be dramatically lowered, based on epidemiological evidence of respiratory health effects among machinists exposed to various metalworking fluid mists. A review of the literature regarding respiratory health effects from either metalworking or non-metalworking fluids suggest that machinists may have experienced slightly higher prevalence of common respiratory symptoms and mild and reversible cross-shift changes in some measures of pulmonary function. However, the inconsistency and potential for both random and systematic error in this body of literature argue against drawing definitive conclusions. There is also no substantive evidence that any of these effects led to permanent disease or impairment. The most likely causal agents for respiratory effects in these workers are microbial contaminants in water-based metalworking fluids, not straight mineral oils. This is consistent with the epidemic outbreaks of hypersensitivity pneumonitis, bronchitis, and asthma reported at some work sites using water-based metalworking fluids. This highlights the importance of frequent cleaning and fluid changes for metalworking fluid reservoirs, as part of a systematic approach to managing metalworking fluid aerosol exposures. A dramatic drop in the TLV for mineral oil mists would not resolve this problem.
authors.affiliation: ExxonMobil Biomedical Sciences, Inc., Annandale, New Jersey, USA.
authors.forename: John A
authors.initials: JA
authors.lastname: Bukowski
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced / Q000453:epidemiology; D004196:Disease Outbreaks; D006801:Humans; D008669:Metallurgy / Q000295:instrumentation* / Q000706:statistics & numerical data; D008899:Mineral Oil / Q000009:adverse effects*; D009017:Morbidity; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D015995:Prevalence; D012129:Respiratory Function Tests; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D020711:Threshold Limit Values; D014481:United States / Q000453:epidemiology
chemical_list: D000395:Air Pollutants, Occupational; D008899:Mineral Oil