title: Emerging trends in high-throughput screening.
abstract: Novel technologies are emerging for high-throughput screening, driven by the needs and fine-tuning of established drug discovery activities, as well as by the emergence of novel target classes resulting from the deciphering of the human genome. Disciplines other than biology have now entered the screening scene, as bioinformatics, micro-technology and analytics provide powerful methodologies and applications that were not previously suitable for high-throughput screening. Many of these will move high-throughput screening from a numbers game to a content- and information-based approach to identify leads for novel disease targets.
authors.affiliation: S*Bio Pte Ltd, 1 Science Park Road, #05-09, The Capricorn, Singapore Science Park II, Singapore 117528, Republic of Singapore. michael_entzeroth@sbio.com
authors.forename: Michael
authors.initials: M
authors.lastname: Entzeroth
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods / Q000639:trends; D019295:Computational Biology / Q000639:trends; D015195:Drug Design; D015894:Genome, Human; D023281:Genomics / Q000639:trends; D006801:Humans; D007473:Ion Channels / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008904:Miniaturization / Q000379:methods; D004364:Pharmaceutical Preparations / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000639:trends*
chemical_list: D007473:Ion Channels; D004364:Pharmaceutical Preparations