title: [[F-18]-fluorodeoxyglucose (FDG) positron emission tomography (PET) as a diagnostic for hip endoprosthesis loosening].
abstract: OBJECTIVE
  The purpose of this study was to examine the FDG-PET in respect of its diagnostic valency with regard to septic/aseptic loosening of lower limb prostheses.
  
  
  METHODS
  28 patients with 41 lower limb prostheses were examined by means of FDG-PET to evaluate septic/aseptic loosening of their hip prostheses. Therefore, a differentiated FDG-PET result interpretation subdivided into five categories was developed. The final diagnosis was based on operative findings with following culture and histological outcome.
  
  
  RESULTS
  The worked-out categories showed a high agreement to the intraoperative macroscopic and histological results (n = 23 correctly positive, n = 1 false positive, n = 1 correctly negative and n = 3 false negative).
  
  
  CONCLUSIONS
  With a subtly differentiated interpretation (categories I - V) of the qualitative glucose metabolism safe statements can be made regarding septic/aseptic endoprostheses loosening. This was impressively confirmed by the agreement of the FDG results with the histological results.
authors.affiliation: Orthopädische Klinik, Universitätsklinikum Aachen. Torsten.Mumme@gmx.de
authors.forename: T
authors.initials: T
authors.lastname: Mumme
authors.forename: P
authors.initials: P
authors.lastname: Reinartz
authors.forename: U
authors.initials: U
authors.lastname: Cremerius
authors.forename: B
authors.initials: B
authors.lastname: Hermanns
authors.forename: R
authors.initials: R
authors.lastname: Müller-Rath
authors.forename: M
authors.initials: M
authors.lastname: Neuss
authors.forename: U
authors.initials: U
authors.lastname: Büll
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019544:Equipment Failure Analysis / Q000379:methods*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18