title: Hypoxic ventilatory response changes of men and women 6 to 7 days after climbing from 2100 m to 4350 m altitude and after descent.
abstract: To test the hypothesis that the changes in hypoxic ventilatory response (HVR) of men and women mountaineers on induction to HA by trekking is not influenced by gender, isocapnic HVR as DeltaV(E)/DeltaSa(O2) was studied in eight men and eight women mountaineering trainees initially at 2100 m, then during 6 to 7 days of sojourn at 4350 m, and retested again on return to 2100 m. Results indicated that HVR at 2100 m increased significantly at 4350 m in both sexes, and the values reverted to baseline level within 4 to 5 days between leaving high altitude (4350 m) and restudy at 2100 m. No sex differences were observed at 2100- or at 4350-m altitude, indicating that men and women have a similar level of chemosensitive response as measured by HVR during induction to HA.
authors.affiliation: Defence Institute of Physiology and Allied Sciences, Defence Research and Development Organization, Lucknow Road, Timarpur, Delhi, India. gbhaumik@mantramail.com
authors.forename: Gopinath
authors.initials: G
authors.lastname: Bhaumik
authors.forename: Ram P
authors.initials: RP
authors.lastname: Sharma
authors.forename: Deepak
authors.initials: D
authors.lastname: Dass
authors.forename: Himmat
authors.initials: H
authors.lastname: Lama
authors.forename: Shri K S
authors.initials: SK
authors.lastname: Chauhan
authors.forename: Shivu S
authors.initials: SS
authors.lastname: Verma
authors.forename: William
authors.initials: W
authors.lastname: Selvamurthy
authors.forename: P K
authors.initials: PK
authors.lastname: Banerjee
mesh_terms: D000064:Acclimatization / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D000531:Altitude; D002245:Carbon Dioxide / Q000378:metabolism; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D009051:Mountaineering / Q000502:physiology*; D010101:Oxygen Consumption / Q000502:physiology; D012123:Pulmonary Ventilation / Q000502:physiology*; D012737:Sex Factors
chemical_list: D002245:Carbon Dioxide