title: Oxidation of guanine nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane.
abstract: Final oxidation products generated from guanosine and 2'-deoxyguanosine by reaction with dimethyldioxirane have been identified as 4-amidinocarbamoyl-5-hydroxyimidazoles.
authors.affiliation: School of Biology and Biochemistry, Queen's University, Belfast, Northern Ireland. j.davies@qub.ac.uk
authors.forename: R Jeremy H
authors.initials: RJ
authors.lastname: Davies
authors.forename: Clarke
authors.initials: C
authors.lastname: Stevenson
authors.forename: Shiv
authors.initials: S
authors.lastname: Kumar
authors.forename: Jason
authors.initials: J
authors.lastname: Lyle
authors.forename: Lisa
authors.initials: L
authors.lastname: Cosby
authors.forename: John F
authors.initials: JF
authors.lastname: Malone
authors.forename: Derek R
authors.initials: DR
authors.lastname: Boyd
authors.forename: Narain D
authors.initials: ND
authors.lastname: Sharma
authors.forename: Ann P
authors.initials: AP
authors.lastname: Hunter
authors.forename: Bridget K
authors.initials: BK
authors.lastname: Stein
mesh_terms: D000578:Amidines; D003849:Deoxyguanosine / Q000737:chemistry*; D004852:Epoxy Compounds; D006151:Guanosine / Q000737:chemistry*; D007093:Imidazoles; D007202:Indicators and Reagents; D010084:Oxidation-Reduction
chemical_list: D000578:Amidines; D004852:Epoxy Compounds; D007093:Imidazoles; D007202:Indicators and Reagents; D006151:Guanosine; D003849:Deoxyguanosine; C064455:dimethyldioxirane