title: Histopathology of the liver in adolescents co-infected with HIV and hepatitis C virus.
abstract: Chronic hepatitis C is usually a mild disease in children; however, the evolution of children co-infected with HIV is unknown. We report the liver biopsy results of seven adolescents co-infected for over 13 years. According to the Metavir scoring system, liver specimens were classified A1-F1 in three patients and A2-F1 in four. Mild fibrosis progression is mainly explained by young age at hepatitis C virus contamination and the lack of severe immunodeficiency in the study population.
authors.affiliation: Department of Pediatrics, Hôpital La Timone, Marseille, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Thuret
authors.forename: Florence
authors.initials: F
authors.lastname: Lacaille
authors.forename: Danielle
authors.initials: D
authors.lastname: Canioni
authors.forename: Bertrand
authors.initials: B
authors.lastname: Roquelaure
authors.forename: Gerard
authors.initials: G
authors.lastname: Michel
authors.forename: Stéphane
authors.initials: S
authors.lastname: Blanche
mesh_terms: D000293:Adolescent; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006526:Hepatitis C / Q000150:complications / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000150:complications / Q000473:pathology; D008297:Male; D013997:Time Factors