A retrospective review comparing the use of Gonal-F and Metrodin-HP for in-vitro fertilisation (IVF).
All cycles of IVF with pituitary down-regulation (n = 57) done at the Damansara Fertility Centre in the year 2000 were studied. All the 57 patients had controlled ovarian hyperstimulation, either using Metrodin HP (n = 27) or Gonal-F (n = 30). Of these, 53 patients reached oocyte pick-up, 26 patients in Metrodin HP group and 27 patients in Gonal-F group. Gonal-F resulted in a higher clinical pregnancy rate of 66.6% compared to Metrodin HP 38.5% (p < 0.05). The live birth rate tends to be higher in Gonal-F group (40.7%) compared to Metrodin HP (30.8%), (p > 0.05).
Lee
Colin
C
Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor.
Mak
F S
FS
Keith
J
J
Welsh
D
D
Yapp
Paulina
P
Chin
Rachel
R
D000328:Adult; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000627:therapeutic use*; D043373:Follicle Stimulating Hormone, Human / Q000627:therapeutic use*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008296:Malaysia / Q000453:epidemiology; D008596:Menotropins / Q000627:therapeutic use*; D008875:Middle Aged; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies
D005300:Fertility Agents, Female; D043373:Follicle Stimulating Hormone, Human; D008596:Menotropins; D005640:Follicle Stimulating Hormone