Donor-related coccidioidomycosis in organ transplant recipients.
Most cases of coccidioidomycosis in organ transplant recipients arise from either primary infection with Coccidioides immitis after environmental exposure or from reactivation of latent infection. Herein, we report 2 cases of rapidly fatal, disseminated coccidioidomycosis that occurred in organ transplant recipients who had never lived in or visited an area where C. immitis is endemic. Both subjects had received a transplanted organ from the same donor, an individual with unrecognized active coccidioidomycosis at the time of his death.
Wright
Patty W
PW
University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
Pappagianis
Demosthenes
D
Wilson
Mark
M
Louro
Ana
A
Moser
Stephen A
SA
Komatsu
Kenneth
K
Pappas
Peter G
PG
D000328:Adult; D003045:Coccidioides; D003047:Coccidioidomycosis / Q000401:mortality* / Q000635:transmission; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation / Q000009:adverse effects*; D014019:Tissue Donors