[Dynamic changes of platelet number in early multiple injury and it is effect on prognosis].
OBJECTIVE
To study the dynamic changes of platelet number in early multiple injured patients and its clinical significance.


METHODS
Ninety patients with multiple injury less than 48 hours were selected. Blood analysis was dynamicly investigated at 1, 24, 72, 120 and 168 hours after in Hospital, and acute physiology and chronic health evaluation III (APACHE III) and injury seriousness scale (ISS) scores were recorded.


RESULTS
The platelet number declined after injury, reached the lowest point at 72 hours after in hospital, then restored to the normal level at 120 hours. In the platelet decrease group, the trauma was more critically[ISS (29.60+/-9.80) scores vs. (22.30+/-12.00) scores, (P<0.05)] and the incidence of multiple organs dysfunction syndrome (MODS) was higher than normal group (83.9% vs. 62.7%, P<0.05). In the death group, the number of platelet was declined[ (30.1+/-10.3) hours vs. (51.3+/-14.8) hours, (P<0.05) and the lasting tine was longer[ (63.7+/-11.0) hours vs. (54.2+/-13.4) hours, (P<0.05).


CONCLUSIONS
The platelet number declines after multiple injury. The decrease and continuously lower level of platelet suggest poor prognosis.
Hao
Jiang
J
Kunming General Hospital, Chengdu Military Region, Kunming 650032, Yunnan, China.
Lei
Ming
M
Zhang
Yin
Y
Zhang
Ping
P
Sun
Chang-ju
CJ
Bian
Ge-yuan
GY
Bai
Li
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000502:physiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology; D009104:Multiple Trauma / Q000097:blood* / Q000150:complications; D010972:Platelet Activating Factor / Q000502:physiology; D010976:Platelet Count; D011379:Prognosis
D010972:Platelet Activating Factor