The growing teratoma syndrome.
Growing teratoma syndrome is defined as enlarging masses of mature teratoma following chemotherapy for malignant nonseminomatous germ-cell tumors. Typically, there is associated normalization of initially elevated serum tumor markers. We describe clinical and imaging findings in a case of growing teratoma syndrome originating from immature teratoma of the ovary in a 12-year-old girl. Familiarity with this unusual entity is important to avoid confusion with advancing malignancy.
Nimkin
Katherine
K
Department of Radiology, The Floating Hospital for Children, Boston, MA, USA. knimkin@partners.org
Gupta
Punita
P
McCauley
Roy
R
Gilchrist
Brian F
BF
Lessin
Marc S
MS
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D013724:Teratoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D014057:Tomography, X-Ray Computed
D000970:Antineoplastic Agents