Normalizing the background and removing the trend in one-dimensional DNA fingerprint images.
Maximizing an individual's genetic information from its DNA fingerprint image depends on the number of bands distinguished from the background. To approach this goal, the background should be normalized while the information is preserved. Morphological operators have been used by some authors to normalize the background for two-dimensional gel images. Methods such as mean, median and "maxpolygon" are presented in this work to normalize the background in DNA fingerprint images. Mean and median methods will lead to some deformations. Visual evaluation of the results show that the original shape of the column signals are better preserved by the maxpolygon.
Akbari
Akbar
A
Department of Infomatics, University of Oslo, P.O. Box 1080, Blindern, N-0316 Oslo, Norway. akbara@ifi.uio.no
Albregtsen
Fritz
F
D016172:DNA Fingerprinting / Q000592:standards*