title: A facile synthetic method for 3'-alpha-fluoro-2',3'-dideoxyadenosine.
abstract: A facile method for the synthesis of 3'-alpha-fluoro-2',3'-dideoxyadenosine (5) has been developed using a novel rearrangement of 3'-beta-bromine to the 2'-beta position during 3'-alpha fluorination.
authors.affiliation: AminoScience Laboratories, Ajinomoto Co., Inc., Kawasaki-ku, Kawasaki, Japan. satoshi-takamatsu@ajinomoto.com
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takamatsu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Katayama
authors.forename: Masaki
authors.initials: M
authors.lastname: Naito
authors.forename: Keizo
authors.initials: K
authors.lastname: Yamashita
authors.forename: Takashi
authors.initials: T
authors.lastname: Ineyama
authors.forename: Kunisuke
authors.initials: K
authors.lastname: Izawa
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis; D016048:Dideoxyadenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D008958:Models, Molecular; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D019380:Anti-HIV Agents; D007202:Indicators and Reagents; C073072:lodenosine; D016048:Dideoxyadenosine