Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XXIV. Derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide.
The preparation of a number of derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide with an expected anxiolytic and antidepressive activity has been described.
Kossakowski
Jerzy
J
Department of Medical Chemistry, Medical University of Warsaw, 3 Oczki Str., 02-007 Warsaw, Poland.
Krawiecka
Mariola
M
D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000928:Antidepressive Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D009682:Magnetic Resonance Spectroscopy; D009043:Motor Activity / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013055:Spectrophotometry, Infrared; D013550:Swimming / Q000523:psychology
D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D001643:Bridged Bicyclo Compounds; C480660:N-hydroxy-1-methoxybicyclo(2.2.2)oct-5-ene-2,3-dicarboximide