title: Efficient characterization of regional mesenteric blood flow by use of laser speckle imaging.
abstract: We present a noninvasive full-field method--laser speckle imaging (LSI)--for measuring the regional mesenteric blood flow without scanning. A system of LSI was designed and validated in a model experiment. Dynamics of regional blood flow in the rat mesentery under the influence of noradrenaline were monitored by this method. Spatial and temporal characteristics of the mesenteric blood-flow response were achieved with high resolution. These suggested that LSI might provide a new approach to microcirculation studies.
authors.affiliation: The Key Laboratory of Biomedical Photonics of the Ministry of Education, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
authors.forename: Haiying
authors.initials: H
authors.lastname: Cheng
authors.forename: Qingming
authors.initials: Q
authors.lastname: Luo
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Hui
authors.initials: H
authors.lastname: Gong
authors.forename: Shangbin
authors.initials: S
authors.lastname: Chen
authors.forename: Wenxi
authors.initials: W
authors.lastname: Liang
authors.forename: Shaoqun
authors.initials: S
authors.lastname: Zeng
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging; D007834:Lasers; D008297:Male; D008962:Models, Theoretical; D051381:Rats; D017208:Rats, Wistar; D013152:Splanchnic Circulation