Lipid signalling: picking out the PIPs.
Many physiological targets have been suggested for polyphosphoinositol lipids, but two out of the three monophosphorylated PIPs appeared to be no more than metabolic precursors. Recent work has shown that they also have distinct binding proteins and functions.
Clarke
Jonathan H
JH
Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD, Cambridge, UK. jhc30@cam.ac.uk
D000818:Animals; D002468:Cell Physiological Phenomena; D006801:Humans; D008958:Models, Molecular; D010716:Phosphatidylinositols / Q000378:metabolism*; D015398:Signal Transduction
D010716:Phosphatidylinositols