[Studies on the effects of chromium complexes].
The existence of chromium complexes in nature, their industrial uses, and their health impacts were reviewed in this paper. The toxic and the formation of Cr(V/IV) complexes and the mechanisms of DNA damage were discussed in particular. The major damaging species responsible for the genotoxicity were Cr(V) or Cr(IV) complexes. However, the function of reactive organic intermediates could not be excluded.
Shi
Liwei
L
Institute for Environmental Hygiene and Health Related Product Safety, Chinese Center for Disease Control, Beijing 100021, China.
D002857:Chromium / Q000737:chemistry / Q000633:toxicity*; D017608:Chromium Compounds / Q000737:chemistry / Q000633:toxicity*; D004247:DNA / Q000187:drug effects; D004249:DNA Damage; D005609:Free Radicals / Q000737:chemistry / Q000633:toxicity; D006801:Humans
D017608:Chromium Compounds; D005609:Free Radicals; D002857:Chromium; D004247:DNA