title: Chondrosarcoma of the bones of the feet.
abstract: Twelve chondrosarcomas of the bones of the feet from 11 patients in the Scottish Bone Tumor Registry were reviewed. One patient with diaphyseal aclasis (osteochondromatosis) developed 2 chondrosarcomas. The mean age of patients was 52.3 years (range, 17 to 83 years). Men were predominantly affected. Four tumors affected the tarsal bones; the rest involved the short tubular bones. The usual clinical presentation was a painful, progressively enlarging swelling. Radiologically, most showed some bone expansion, cortical destruction with indistinct margins, and soft-tissue extension. Histologically, the majority were middle-grade tumors. Treatment included curettage or local excision for 4 tumors and amputation or ray resection for 8 tumors. Follow-up varied from 6 months to 18 years (average, 5.8 years). Local recurrence after surgery was seen in 3 patients. All 3 died because of metastases to the lungs or brain.
authors.affiliation: University Department of Orthopedic Surgery, Department of Pathology, Western Infirmary, Glasgow, Scotland. shaila@sanjeev.freeserve.co.uk
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Patil
authors.forename: M V Chandu
authors.initials: MV
authors.lastname: de Silva
authors.forename: Jim
authors.initials: J
authors.lastname: Crossan
authors.forename: Robin
authors.initials: R
authors.lastname: Reid
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery*; D002813:Chondrosarcoma / Q000473:pathology / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D005529:Foot Bones / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged