title: Deposition and clearance for radon progeny in the human respiratory tract.
abstract: In vivo counting of 214Pb was conducted to estimate the deposition and retention of radon progeny in the human respiratory tract. Two volunteer subjects were exposed to high radon concentrations. After the exposures, activity deposited in the extrathoracic (ET) region for each subject was measured using a NaI(Tl) detector. According to the International Commission on Radiological Protection (ICRP) model, a reference value for particle transport rate from ET2 to the GI tract is 100 d(-1) (half-time, 10 min). The effective half-time of 214Pb deposited in the ET region was calculated for pure nose and mouth breathers, using the ICRP reference transport rate. While the measured half-times for nose breathers were generally consistent with the calculated values, those for mouth breathers were significantly larger than the calculated values. The results indicated that the particle transport rate from ET2 to the GI tract was much smaller than the reference value in the ICRP model.
authors.affiliation: Radon Research Group, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. tetsuo_i@nirs.go.jp
authors.forename: T
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Fukutsu
authors.forename: S
authors.initials: S
authors.lastname: Tokonami
mesh_terms: D000042:Absorption; D000280:Administration, Inhalation; D000328:Adult; D000398:Air Pollution, Radioactive / Q000032:analysis*; D003198:Computer Simulation; D006801:Humans; D019570:Inhalation Exposure; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D008954:Models, Biological; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D017687:Radon Daughters / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D015656:Respiratory Mechanics / Q000502:physiology*; D012137:Respiratory System / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D017687:Radon Daughters