title: [Current methods of ulcer therapy and their efficacy and cost].
abstract: The purpose of this study is to assess the efficiency of the anti-ulcer therapy taking into account the economic aspects of treatment. We have examined 708 HP-positive(+) patients with stomach ulcers (SU) and duodenal ulcers (DU). Various schemes of anti-helicobacter and anti-secretory therapy were administered to them. Positive dynamics of some clinical data (local palpatory tenderness and abdominal wall resistance) and gastritis (gastroduodenitis) activity was discovered in all groups of patients. The cost of the treatment was determined with the help of marketing studies by taking the lowest price of drugs. There were no statistically reliable differences found groups of traditional treatment regimens by both results of HP eradication and the cost of eradicative and anti-secretory therapy. All drugs under study are highly effective for rapid relief of symptoms at an exacerbation of stomach ulcer associated with HP as well as the decrease of gastritis (gastroduodenitis) activity. It is possible to recommend them for both eradicative therapy and prolonged treatment.
authors.affiliation: Russian State Medical University, Moscow.
authors.forename: P Ia
authors.initials: PIa
authors.lastname: Grigor'ev
authors.forename: E P
authors.initials: EP
authors.lastname: Iakovenko
authors.forename: I P
authors.initials: IP
authors.lastname: Soluianova
authors.forename: M A
authors.initials: MA
authors.lastname: Abdulzhapparova
authors.forename: E V
authors.initials: EV
authors.lastname: Talanova
authors.forename: I N
authors.initials: IN
authors.lastname: Usankova
authors.forename: A S
authors.initials: AS
authors.lastname: Prianishnikova
authors.forename: N A
authors.initials: NA
authors.lastname: Agafonova
authors.forename: P V
authors.initials: PV
authors.lastname: Guliaev
authors.forename: A V
authors.initials: AV
authors.lastname: Iakovenko
authors.forename: I V
authors.initials: IV
authors.lastname: Vasil'ev
authors.forename: B I
authors.initials: BI
authors.lastname: Obukhovskiĭ
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000191:economics / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D004381:Duodenal Ulcer / Q000188:drug therapy; D005260:Female; D005756:Gastritis / Q000188:drug therapy; D016481:Helicobacter Infections / Q000188:drug therapy; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D013276:Stomach Ulcer / Q000188:drug therapy; D013997:Time Factors; D016896:Treatment Outcome; D014456:Ulcer / Q000188:drug therapy*
chemical_list: D000897:Anti-Ulcer Agents