Distribution of variant genotypes of Fc gamma receptor IIIa in healthy Chinese population of Zhengzhou City.
To investigate the distribution of variant genotypes of Fc gamma receptor IIIa (Fc gamma R IIIa) in healthy Chinese population of Zhengzhou city, genomic DNA was extracted from peripheral blood of healthy donators. The genotypes of Fc gamma R IIIa-158 were determined by nested polymerase chain reaction (PCR) in 137 healthy people in Zhengzhou city. The results showed that frequencies of variant genotypes FF, VV and VF were 42.3%, 48.9% and 8.8% respectively. The distribution of Fc gamma R IIIa-158 in healthy Chinese population of Zhengzhou city was polymorphic and different from that of African Americans (AA) and Caucasian Americans (CA).
Wang
Jun
J
Department of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Feng
Jianfei
J
Zhang
Li
L
Hu
Yu
Y
Luan
Bin
B
Yue
Weihai
W
Wang
Hong
H
Zhu
Shaoxian
S
Xu
Yumei
Y
D044466:Asian People; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017452:Receptors, IgG / Q000235:genetics*; D044465:White People
D017452:Receptors, IgG