How does the hippocampus contribute to memory?
Recently, Wirth et al. reported that hippocampal neurons signal the acquisition of new associations by altering the selectivity of their responses to crucial stimuli. The course of these changes was gradual, with some neurons recruited before, others at the time of, and yet others shortly after learning. These observations suggest the hippocampus might contribute to memory by identifying consistencies across experiences that constitute important new associations.
Eichenbaum
Howard
H
Center for Memory and Brain, 2 Cummington Street, Boston University, Boston, MA 02215, USA. hbe@bu.edu