[Clinical evaluation of provitamin B5 drops and gel for postoperative treatment of corneal and conjuctival injuries].
OBJECTIVE
Vitamins B group are important ingredients of coenzymes. Provitamin B5 dexpanthenol is necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties. Objective of the study was to determine how the wounds of cornea and/or conjunctiva heal upon the application of D-panthenol/the medicine has been developed in the Faculty of Pharmacy of the Medical University of Gdańsk/.


METHODS
The activity of the medicine was tested in 40 eyes in the test group, a 40 eyes in the control group did not receive D-panthenol. The degree of the objective and subjective symptoms was assessed.


RESULTS
The differences between the two groups commenced on the second day following the operation. Better effects were observed in patients receiving D-panthenol. Congestion and oedema of conjunctiva withdrew, the edges of wounds demonstrated smoothness and better adherence. Subjective feelings improved.


CONCLUSIONS
1. Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.
Raczyńska
Krystyna
K
Katedry i Kliniki Chorób Oczu Akademii Medycznej w Gdańsku.
Iwaszkiewicz-Bilikiewicz
Barbara
B
Stozkowska
Wiesława
W
Sadlak-Nowicka
Jadwiga
J
D003228:Conjunctiva / Q000293:injuries / Q000601:surgery*; D003315:Cornea / Q000601:surgery*; D065306:Corneal Injuries; D019573:Epithelium, Corneal; D005131:Eye Injuries / Q000188:drug therapy / Q000209:etiology; D005782:Gels; D006801:Humans; D007646:Keratotomy, Radial / Q000009:adverse effects; D008875:Middle Aged; D009883:Ophthalmic Solutions; D010205:Pantothenic Acid / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D018918:Phacoemulsification / Q000009:adverse effects; D011182:Postoperative Care / Q000379:methods*; D014945:Wound Healing / Q000187:drug effects*
D005782:Gels; D009883:Ophthalmic Solutions; D010205:Pantothenic Acid; C007288:dexpanthenol