title: Pharmacological evaluation of 5-[2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl]-1,3-dihydro-benzimidazole-2-thione as a potential atypical antipsychotic agent.
authors.affiliation: Department of Biochemistry, Institute for Biological Research, University of Belgrade, Belgrade, Serbia and Montenegro. mitomic@ibiss.bg.ac.yu
authors.forename: M
authors.initials: M
authors.lastname: Tomić
authors.forename: M
authors.initials: M
authors.lastname: Kundaković
authors.forename: B
authors.initials: B
authors.lastname: Butorović
authors.forename: V
authors.initials: V
authors.lastname: Vasilev
authors.forename: D
authors.initials: D
authors.lastname: Dragović
authors.forename: G
authors.initials: G
authors.lastname: Roglić
authors.forename: D J
authors.initials: DJ
authors.lastname: Ignjatović
authors.forename: V
authors.initials: V
authors.lastname: Soskić
authors.forename: S
authors.initials: S
authors.lastname: Kostić-Rajacić
mesh_terms: D000818:Animals; D014150:Antipsychotic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D002375:Catalepsy / Q000139:chemically induced; D000697:Central Nervous System Stimulants / Q000037:antagonists & inhibitors / Q000494:pharmacology; D003913:Dextroamphetamine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D016291:Dizocilpine Maleate / Q000037:antagonists & inhibitors / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D018728:Entorhinal Cortex / Q000378:metabolism; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D008996:Monoamine Oxidase Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects; D011869:Radioligand Assay; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects / Q000378:metabolism; D011985:Receptors, Serotonin / Q000187:drug effects / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology; D013239:Stereotyped Behavior / Q000187:drug effects; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism; D013871:Thiones / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D014150:Antipsychotic Agents; D001562:Benzimidazoles; D000697:Central Nervous System Stimulants; D003913:Dextroamphetamine; D016291:Dizocilpine Maleate; D018691:Excitatory Amino Acid Antagonists; D008996:Monoamine Oxidase Inhibitors; D011954:Receptors, Dopamine; D011985:Receptors, Serotonin; D017367:Selective Serotonin Reuptake Inhibitors; D013871:Thiones; C478426:5-(2-(4-(2-methoxy-phenyl)-piperazin-1-yl)-ethyl)-1,3-dihydro-benzimidazole-2-thione