Pharmacological evaluation of 5-[2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl]-1,3-dihydro-benzimidazole-2-thione as a potential atypical antipsychotic agent.
Tomić
M
M
Department of Biochemistry, Institute for Biological Research, University of Belgrade, Belgrade, Serbia and Montenegro. mitomic@ibiss.bg.ac.yu
Kundaković
M
M
Butorović
B
B
Vasilev
V
V
Dragović
D
D
Roglić
G
G
Ignjatović
D J
DJ
Soskić
V
V
Kostić-Rajacić
S
S
D000818:Animals; D014150:Antipsychotic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D002375:Catalepsy / Q000139:chemically induced; D000697:Central Nervous System Stimulants / Q000037:antagonists & inhibitors / Q000494:pharmacology; D003913:Dextroamphetamine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D016291:Dizocilpine Maleate / Q000037:antagonists & inhibitors / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D018728:Entorhinal Cortex / Q000378:metabolism; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D008996:Monoamine Oxidase Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects; D011869:Radioligand Assay; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects / Q000378:metabolism; D011985:Receptors, Serotonin / Q000187:drug effects / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology; D013239:Stereotyped Behavior / Q000187:drug effects; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism; D013871:Thiones / Q000138:chemical synthesis* / Q000494:pharmacology
D014150:Antipsychotic Agents; D001562:Benzimidazoles; D000697:Central Nervous System Stimulants; D003913:Dextroamphetamine; D016291:Dizocilpine Maleate; D018691:Excitatory Amino Acid Antagonists; D008996:Monoamine Oxidase Inhibitors; D011954:Receptors, Dopamine; D011985:Receptors, Serotonin; D017367:Selective Serotonin Reuptake Inhibitors; D013871:Thiones; C478426:5-(2-(4-(2-methoxy-phenyl)-piperazin-1-yl)-ethyl)-1,3-dihydro-benzimidazole-2-thione