[Effect of Smilax china on adjunctive arthritis mouse].
OBJECTIVE
To study the therapeutic action of decoction of Smilax china L. on adjunctive arthritis(AA) mouse and its mechanism.


METHODS
To observe the change of secondary inflammation, thymus and spleen weights, T cell subgroup, B cell, NK cell.


RESULTS
The decoction (90, 180 g.kg-1) intragastric injection (ig) could significantly inhibit AA mouse's secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell.


CONCLUSIONS
The decoction has therapeutic action by regulating cell-mediated immunity, but has little effect on humoral immunity.
Lü
Yongning
Y
Affiliated Xiehe Hospital, Tongji Medical College, China University of Science and Technology, Wuhan 430030.
Chen
Dongsheng
D
Deng
Jungang
J
Tian
Lianqi
L
D000276:Adjuvants, Immunologic / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000276:immunology*; D016516:CD4-CD8 Ratio; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D032281:Smilax / Q000737:chemistry*
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal