A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols.
Lipophilic tea polyphenols (LTP) were prepared by catalytic esterification of green tea polyphenols (GTP) with hexadecanoyl chloride. A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate (EGCG) was first isolated from purification of LTP by high-speed countercurrent chromatography (HSCCC) using a solvent system composed of n-hexane-ethyl acetate-methanol-water (1:1:1:1, v/v). The molecular structure of the acyl-derivative, Epigallocatechin-3-O-gallate-4'-O-hexadecanate, was elucidated by means of elemental analysis, IR, (1)H-NMR and MS spectra
Chen
Ping
P
Catalysis Institute, Zhejiang University, Hangzhou 310028, China. pingchen@mail.hz.zj.cn
Tan
Yao
Y
Sun
Dong
D
Zheng
Xiao-ming
XM
D000215:Acylation; D002392:Catechin / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004951:Esterification; D005419:Flavonoids / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry*; D059808:Polyphenols; D013055:Spectrophotometry, Infrared; D013662:Tea / Q000737:chemistry*
D005419:Flavonoids; D006843:Hydrocarbons, Chlorinated; D010636:Phenols; D059808:Polyphenols; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate