title: Thyrotoxicosis after complete or partial lithium withdrawal in two patients with bipolar affective disorder.
abstract: OBJECTIVE
  To highlight and discuss thyrotoxicosis after lithium withdrawal as a potential complication of lithium therapy for bipolar disorder.
  
  
  METHODS
  Both patients presented developed thyrotoxicosis, the first patient after stopping the lithium completely, and the second patient after a reduction in the lithium dose.
  
  
  CONCLUSIONS
  Clinicians should be alert to the possibility of thyrotoxicosis emerging when lithium is being completely or partially withdrawn. Such withdrawal could unmask a latent hyperthyroidism.
authors.affiliation: Mental Health Department, Clacton and District Hospital, Clacton on Sea, Essex, UK. cdcarmaciu@aol.com
authors.forename: C D
authors.initials: CD
authors.lastname: Carmaciu
authors.forename: C S
authors.initials: CS
authors.lastname: Anderson
authors.forename: C A
authors.initials: CA
authors.lastname: Lawton
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000150:complications* / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012008:Recurrence; D013375:Substance Withdrawal Syndrome / Q000209:etiology*; D013971:Thyrotoxicosis / Q000139:chemically induced*
chemical_list: D008094:Lithium