title: Pathologic aspects of AIDS malignancies.
abstract: Since the emergence of the HIV pandemic, a close association between HIV infection and the development of a selected group of cancers has been acknowledged. The introduction of highly active antiretroviral therapy, however, has had a dramatic impact on the incidences of several AIDS-defining malignancies. This suggests the possibility of a direct and indirect role of HIV in HIV-related tumor genesis. The aim of this paper is to review the pathology of AIDS-related malignancies, taking into account the pathogenetic mechanisms and their potential for improving the treatment of these tumors.
authors.affiliation: Department of Human Pathology and Oncology, University of Siena, Siena, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Bellan
authors.forename: G
authors.initials: G
authors.lastname: De Falco
authors.forename: S
authors.initials: S
authors.lastname: Lazzi
authors.forename: L
authors.initials: L
authors.lastname: Leoncini
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000235:genetics; D005260:Female; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000235:genetics; D009369:Neoplasms / Q000209:etiology* / Q000235:genetics; D012514:Sarcoma, Kaposi / Q000235:genetics; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000235:genetics