title: Determination of binding affinities of triplex forming oligonucleotides using a fluorescent intercalator displacement (FID) assay.
abstract: The binding affinities of several triplex forming oligonucleotides were determined using a fluorescent intercalator displacement (FID) assay.
authors.affiliation: Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Bryan K S
authors.initials: BK
authors.lastname: Yeung
authors.forename: Winston C
authors.initials: WC
authors.lastname: Tse
authors.forename: Dale L
authors.initials: DL
authors.lastname: Boger
mesh_terms: D000465:Algorithms; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004247:DNA / Q000737:chemistry; D004996:Ethidium / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007364:Intercalating Agents / Q000737:chemistry*; D007700:Kinetics; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000032:analysis / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D005456:Fluorescent Dyes; D007364:Intercalating Agents; D009841:Oligonucleotides; D004247:DNA; D004996:Ethidium