title: Chemical composition and antifungal activity of essential oils of seven Moroccan Labiatae against Botrytis cinerea Pers: Fr.
abstract: Essential oils of seven Moroccan Labiatae were chemically analysed by GC-MS and evaluated for their in vitro antifungal activity against Botrytis cinerea. Among them, Origanum compactum and Thymus glandulosus greatly inhibited the growth of the mycelium. The inhibition of Botrytis cinerea was 100% for both oils at 100 ppm, while the IC(50)s were 35.1 and 79.2 ppm, respectively. Mentha pulegium exhibited moderate activity at 250 ppm since the inhibition of the mycelial growth was 58.5% and the IC(50) was 233.5 ppm. The main constituents of the studied oils were also examined. Thymol and carvacrol that are the two main constituents of Thymus glandulosus and Origanum compactum exhibited the strongest antifungal activity with 100% of inhibition at 100 ppm, respectively.
authors.affiliation: UFR, Substances Naturelles, Laboratoire de Chimie, Biochimie, Biologie et Biologie Moléculaire, Faculté de Médecine et de Pharmacie, B.P. 6388 Rabat Instituts, Rabat, Morocco.
authors.forename: Chebli
authors.initials: C
authors.lastname: Bouchra
authors.forename: Mohamed
authors.initials: M
authors.lastname: Achouri
authors.forename: L M
authors.initials: LM
authors.lastname: Idrissi Hassani
authors.forename: Mohamed
authors.initials: M
authors.lastname: Hmamouchi
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D020171:Botrytis / Q000187:drug effects*; D015169:Colony Count, Microbial; D008401:Gas Chromatography-Mass Spectrometry; D020128:Inhibitory Concentration 50; D019686:Lamiaceae; D009018:Morocco; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D009822:Oils, Volatile