Mining genome databases for therapeutic gold: SIM2 is a novel target for treatment of solid tumors.
Ratan
Rajiv R
RR
Department of Neurology, Program in Neuroscience, and Center for Neurodegeneration and Repair, Harvard Medical School and Burke/Cornell Medical Research Institute, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. rratan@caregroup.harvard.edu
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D051792:Basic Helix-Loop-Helix Proteins; D019295:Computational Biology; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins; D015698:Genomic Library; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*
D000970:Antineoplastic Agents; D051792:Basic Helix-Loop-Helix Proteins; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D009687:Nuclear Proteins; C417032:SIM2 protein, human; C089449:sim protein, Drosophila