title: The pathogenicity of canine parvovirus type-2b, FP84 strain isolated from a domestic cat, in domestic cats.
abstract: Canine parvovirus type-2a (CPV-2a) and type-2b (CPV-2b) have recently been isolated from domestic cats. The pathogenicity of CPV-2b in domestic cats is still unclear. In this study, we performed infection tests to examine the pathogenicity of CPV-2b, FP84 strain, isolated from a domestic cat. The results demonstrated that the CPV strain FP84 is able to infect and replicate well in domestic cats. Two of the 3 cats used in the test died. They showed loss of appetite, diarrhea, leukopenia and dehydration. Since FP84 was found to be virulent to domestic cats, it is necessary to examine the efficacy of inactivated feline panleukopenia virus vaccines against CPV infection in domestic cats.
authors.affiliation: National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Kokubunji, Tokyo, Japan.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Gamoh
authors.forename: Yohko
authors.initials: Y
authors.lastname: Shimazaki
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Makie
authors.forename: Megumi
authors.initials: M
authors.lastname: Senda
authors.forename: Osamu
authors.initials: O
authors.lastname: Itoh
authors.forename: Yoshimitu
authors.initials: Y
authors.lastname: Inoue
mesh_terms: D000818:Animals; D001831:Body Temperature; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D003967:Diarrhea / Q000209:etiology / Q000662:veterinary; D004285:Dogs; D007958:Leukocyte Count; D010322:Parvoviridae Infections / Q000635:transmission / Q000662:veterinary*; D017993:Parvovirus, Canine / Q000302:isolation & purification* / Q000472:pathogenicity