title: Virulence factors of uropathogenic Escherichia coli.
abstract: Virulence factors of Escherichia coli are of two main types; those produced on the surface of the cell and those produced within the cell and then exported to the site of action. Those on the surface include different sorts of fimbriae that have a role in adhesion to the surface of host cells but may also have additional roles such as tissue invasion, biofilm formation or cytokine induction. The activities of cell wall components are discussed and several exported virulence factors are described that have anti host cell activities. Others virulence factors enable the bacteria to grow in an environment of iron restriction.
authors.affiliation: Department of Medical Microbiology and Immunology, University Medical School of Pécs, Szigeti ut 12, H-7624, Pécs, Hungary. levente.emody@aok.pte.hu
authors.forename: L
authors.initials: L
authors.lastname: Emody
authors.forename: M
authors.initials: M
authors.lastname: Kerényi
authors.forename: G
authors.initials: G
authors.lastname: Nagy
mesh_terms: D000818:Animals; D018441:Biofilms; D004926:Escherichia coli / Q000472:pathogenicity* / Q000502:physiology*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000378:metabolism; D052776:Female Urogenital Diseases / Q000382:microbiology*; D036781:Fimbriae Proteins / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006460:Hemolysin Proteins / Q000378:metabolism; D006801:Humans; D008070:Lipopolysaccharides / Q000378:metabolism; D052801:Male Urogenital Diseases; D014774:Virulence / Q000502:physiology
chemical_list: D029968:Escherichia coli Proteins; D006460:Hemolysin Proteins; C036507:Hlya protein, E coli; D008070:Lipopolysaccharides; D036781:Fimbriae Proteins