title: [Minimal Change Glomerulonephritis].
abstract: We report two cases of minimal change glomerulonephritis (synonyms: idiopathic nephrotic syndrom, minimal change disease). A 47-year old female patient was admitted to our unit with a relapsing nephrotic syndrome since childhood. Another patient, a 22-year old female, presented with moderately swollen legs that developed over several months and a complaint of frequent upper respiratory tract infections during the last year. In both cases we suspected a minimal change glomerulonephritis which can only be proven by renal biopsy. Therapeutic options comprise steroids, cyclosporin, tacrolimus or even cyclophosphamide, depending on the clinical presentation of the disease in the individual case.
authors.affiliation: Sektion Nephrologie, Universitätsklinik Ulm, Germany. sylvia.stracke@medizin.uni-ulm.de
authors.forename: S
authors.initials: S
authors.lastname: Stracke
authors.forename: U
authors.initials: U
authors.lastname: Helmchen
authors.forename: C
authors.initials: C
authors.lastname: Aymanns
authors.forename: N
authors.initials: N
authors.lastname: Kadlec
authors.forename: B
authors.initials: B
authors.lastname: Lindemann
authors.forename: S
authors.initials: S
authors.lastname: Hüttner
authors.forename: F
authors.initials: F
authors.lastname: Keller
mesh_terms: D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000188:drug therapy* / Q000473:pathology*; D013256:Steroids / Q000627:therapeutic use*; D016559:Tacrolimus / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D013256:Steroids; D016572:Cyclosporine; D003520:Cyclophosphamide; D016559:Tacrolimus