[Study of the extraction technique of volatile oil from Chinese herbs for manufacturing Xiaoerjianpixiaoshi oral solution].
OBJECTIVE
To determine the optimal extracting technique for the volatile oil from the Chinese herbs for manufacturing Xiaoerjianpixiaoshi oral solution.


METHODS
Two steam distillation processes were carried out to extract the volatile oil from three Chinese herbs. UV-spectrophotometry method was used to determine the oil content in the distillate, and the mathematical model was established according to volatile oil distillation process by exponential curve regression analysis.


RESULTS
Direct extraction of the oil by means of steam distillation process was more workable, and the decrement of oil content conformed well with the exponential model. Collection of 2 volumes of the distillate resulted in the yield of volatile oil of 61.64%.


CONCLUSIONS
The optimal extraction of the volatile oil can be resulted from immersion of the drugs in 8 volumes of water for 0.5 h and collection of 2 volumes of the distillate.
Zhou
Ben-jie
BJ
Department of Pharmacy, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China.
Guo
Qian
Q
D000284:Administration, Oral; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D006801:Humans; D009822:Oils, Volatile / Q000032:analysis*; D012044:Regression Analysis
D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile