title: Synthesis of beta-substituted cationic porphyrins and their interactions with DNA.
abstract: The beta-substituted cationic porphyrins (7, 8 and 10) have been synthesized and their interactions with plasmid DNA investigated. We found that substituents at the beta-position of porphyrins (7 and 8) have apparently affected their interactions with DNA compared with non-beta-substituted porphyrins (10).
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Hubei Wuhan 430072, P.R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Wen
authors.initials: W
authors.lastname: Qin
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Tian
authors.initials: T
authors.lastname: Tian
authors.forename: Hongjuan
authors.initials: H
authors.lastname: Ma
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Cao
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Wu
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Xiao-Lian
authors.initials: XL
authors.lastname: Zhang
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
authors.forename: Fang
authors.initials: F
authors.lastname: Zheng
authors.forename: Xia
authors.initials: X
authors.lastname: Li
mesh_terms: D000042:Absorption; D002412:Cations; D004247:DNA / Q000187:drug effects*; D004249:DNA Damage; D004587:Electrophoresis, Agar Gel; D010777:Photochemistry; D010957:Plasmids / Q000187:drug effects; D011166:Porphyrins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D002412:Cations; D011166:Porphyrins; D004247:DNA