title: Balloon angioplasty of native coarctation of the aorta in a local group of children: acute results and midterm angiographic re-assessment.
abstract: OBJECTIVE
  Balloon angioplasty of native coarctation of the aorta is gaining acceptance as an alternative to surgery in children. The aim of this study was to assess the acute and midterm effectiveness and safety of the procedure.
  
  
  METHODS
  During a 3-year period, nine patients with native coarctation underwent balloon angioplasty at a median age of 2.9 years (range: 4 mo - 12 y) and median weight of 11 kg (range: 3.1 - 51 kg). Balloon diameter selected was at least twice the diameter of the narrowed segment, but never more than the diameter of the aorta at diaphragmatic level.
  
  
  RESULTS
  There was a significant improvement in the mean systolic gradient across the coarctation from 36 +/- 13mm Hg to 4 +/- 4 mm Hg (p < 0.001), and in the mean diameter of the narrowed segment from 4 +/- 1.3 mm to 7.2 +/- 2.7 mm (p < 0.001). There was no immediate mortality or complication. Follow-up catheterisation was done in eight patients, a mean of 2.7 years (range: 0.8 - 4 y) after the initial procedure. No evidence of restenosis was found, but one patient developed an aneurysm that was surgically resected.
  
  
  CONCLUSIONS
  Balloon angioplasty is effective and safe for the treatment of native coarctation in children. Radiographic follow-up is advisable in the midterm. Balloon angioplasty offers an alternative to surgery in the treatment of selected children older than 3 months with native coarctation of the aorta.
authors.affiliation: Paediatric Cardiology, Department of Paediatrics and Child Health-G69, University of the Free State, Bloemfontein, South Africa.
authors.forename: S C
authors.initials: SC
authors.lastname: Brown
authors.forename: A D
authors.initials: AD
authors.lastname: Bruwer
mesh_terms: D000792:Angiography / Q000379:methods; D000800:Angioplasty, Balloon / Q000379:methods*; D001017:Aortic Coarctation / Q000000981:diagnostic imaging* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011336:Probability; D011446:Prospective Studies; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome