title: Treatment options and new therapeutic approaches in atopic dermatitis.
abstract: Many patients with atopic dermatitis feel that their treatment is ineffective and 25% may be noncompliant with treatments involving corticosteroids. Developing safe and effective pharmacologic alternatives to steroids has presented a challenge to physicians and drug researchers. A new class of nonsteroid immunomodulators, topical calcineurin inhibitors, overcome some of the difficulties and concerns associated with steroid use. The introduction of new drug therapies reinforces the importance of dermatology nursing in managing atopic dermatitis.
authors.affiliation: Division of Pediatric Allergy-Immunology, Department of Pediatrics, National Jewish Medical and Research Center, University of Colorado School of Medicine, Denver, CO, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Boguniewicz
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D065095:Calcineurin Inhibitors; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000451:nursing; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D065095:Calcineurin Inhibitors; D007166:Immunosuppressive Agents; C117268:pimecrolimus; D016559:Tacrolimus