title: [Simplified diagnosis of deep venous thrombosis by applying clinical score and D-dimer concentration].
abstract: Serial compression ultrasonography of the leg is a safe but inefficient method of diagnosing deep venous thrombosis (DVT). The introduction of the clinical score and the D-dimer test heralds a change in the diagnostics of DVT. It is now safe to withhold anticoagulation from patients following one single normal ultrasonography in combination with a low clinical score or a normal D-dimer concentration. Recent studies show that DVT can safely be excluded on the basis of the combination of a normal D-dimer concentration and a low clinical score alone.
authors.affiliation: Universitair Medisch Centrum Utrecht, afd. Hematologie, Heidelberglaan 100, 3584 CX Utrecht. schutgensvos@hetnet.nl
authors.forename: R E
authors.initials: RE
authors.lastname: Schutgens
authors.forename: D H
authors.initials: DH
authors.lastname: Biesma
mesh_terms: D003937:Diagnosis, Differential; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000175:diagnosis*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D