title: [Intraoperative use of an open mid-field MR scanner in the surgical treatment of cerebral gliomas].
abstract: The aim of the present study was to evaluate the effectiveness of intraoperative MRI guidance in achieving more gross-total resection in case of primary brain tumors. We studied 12 patients with low-grade glioma and 19 patients with high-grade glioma who underwent surgery within a vertically open 0.5 T MR system. After initial imaging, the resection was stopped at the point in which the neurosurgeon considered the resection complete by viewing the operation field. At this time, intraoperative MRI was repeated ("first control") to identify any residual tumor. Areas of tumor-suspected tissue were localized and resected, with the exception of tissue adjacent to eloquent areas. Final imaging was carried out before closing the craniotomy. Comparison of "first control" and final imaging revealed a decrease of residual tumor volume from 32% to 4.3% in low-grade gliomas, and from 29% to 10% in high-grade gliomas. Intraoperative MRI allows a clear optimization of microsurgical resection of both low-grade and high-grade gliomas.
authors.affiliation: Klinik und Poliklinik für Diagnostische Radiologie, Universität Leipzig. schneidj@medizin.uni-leipzig.de
authors.forename: Jens-Peter
authors.initials: JP
authors.lastname: Schneider
authors.forename: Christos
authors.initials: C
authors.lastname: Trantakis
authors.forename: Thomas
authors.initials: T
authors.lastname: Schulz
authors.forename: Jürgen
authors.initials: J
authors.lastname: Dietrich
authors.forename: Thomas
authors.initials: T
authors.lastname: Kahn
mesh_terms: D001932:Brain Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005909:Glioblastoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005910:Glioma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D016343:Monitoring, Intraoperative / Q000379:methods*; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome