Alpha-cycloPNA: 1-aminocylopentane-1-carboxylic acid-derived peptide nucleic acid.
All four diastereoisomers of 3-thymine-1-((t)butoxycarbonyl)aminocyclopentane-1-carboxylic acid have been synthesised from (S)-dimethyl malate and thymine monomer 12 has been incorporated into an alpha-cycloPNA oligomer.
Howarth
Nicola M
NM
Chemistry, School of Engineering and Physical Sciences, Heriot-Watt University, Riccarton, Edinburgh, UK. n.m.howarth@hw.ac.uk
Wakelin
Laurence P G
LP
Walker
David M
DM
D003515:Cycloleucine / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D007202:Indicators and Reagents; D020135:Peptide Nucleic Acids; D003515:Cycloleucine