title: Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma.
abstract: In this study, we have shown that there are seasonal differences in the onset of the (Epstein-Barr virus) EBV-positive and -negative forms of paediatric Hodgkin's lymphoma (HL). This suggests aetiological differences between the two forms of this disease. EBV-positive HL might be a rare consequence of primary EBV infection.
authors.affiliation: Department of Pathology, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
authors.forename: A
authors.initials: A
authors.lastname: Reiman
authors.forename: J E
authors.initials: JE
authors.lastname: Powell
authors.forename: K J
authors.initials: KJ
authors.lastname: Flavell
authors.forename: R G
authors.initials: RG
authors.lastname: Grundy
authors.forename: J R
authors.initials: JR
authors.lastname: Mann
authors.forename: S
authors.initials: S
authors.lastname: Parkes
authors.forename: D
authors.initials: D
authors.lastname: Redfern
authors.forename: L S
authors.initials: LS
authors.lastname: Young
authors.forename: P G
authors.initials: PG
authors.lastname: Murray
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000453:epidemiology / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007231:Infant, Newborn; D015995:Prevalence; D012621:Seasons; D006113:United Kingdom / Q000453:epidemiology; D014763:Viral Matrix Proteins / Q000032:analysis
chemical_list: C037662:EBV-associated membrane antigen, Epstein-Barr virus; D014763:Viral Matrix Proteins