title: [A case of duodenal adenocarcinoma arising from the heterotopic pancreas].
abstract: Heterotopic pancreas, defined as the presence of pancreatic tissue that lacks anatomic and vascular continuity with the pancreas proper, may be more likely to undergo malignant change. However, malignancy arising from heterotopic pancreas is rare. In Korea, only one case of adenocarcinoma arising from a gastric heterotopic pancreas has been reported. Recently, we experienced a case of duodenal carcinoma arising from heterotopic pancreas in a 64-year-old man. Endoscopic biopsy of the stenotic duodenum was positive for adenocarcinoma, and he underwent a pancreaticoduodenectomy with subtotal gastrectomy. Histologic examination of the resected specimen satisfied the proposed conditions that are necessary to prove that a malignancy arose from heterotopic pancreas. Despite an adjuvant chemotherapy, he died 10 months after surgery. Herein, we report a case of duodenal adenocarcinoma arising from heterotopic pancreas with a review of the relevant literature.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Joo Young
authors.initials: JY
authors.lastname: Nam
authors.forename: Sang In
authors.initials: SI
authors.lastname: Lee
authors.forename: Jun Pyo
authors.initials: JP
authors.lastname: Chung
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Dok Yong
authors.initials: DY
authors.lastname: Lee
authors.forename: Jae Phil
authors.initials: JP
authors.lastname: Choi
authors.forename: Jung Il
authors.initials: JI
authors.lastname: Lee
authors.forename: Se Joon
authors.initials: SJ
authors.lastname: Lee
authors.forename: Kwan Sik
authors.initials: KS
authors.lastname: Lee
authors.forename: Jin Kyung
authors.initials: JK
authors.lastname: Kang
authors.forename: Seung Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Ki Whang
authors.initials: KW
authors.lastname: Kim
authors.forename: Beom Jin
authors.initials: BJ
authors.lastname: Lim
authors.forename: Chan Il
authors.initials: CI
authors.lastname: Park
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D002828:Choristoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology