Determination of binding affinities of triplex forming oligonucleotides using a fluorescent intercalator displacement (FID) assay.
The binding affinities of several triplex forming oligonucleotides were determined using a fluorescent intercalator displacement (FID) assay.
Yeung
Bryan K S
BK
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Tse
Winston C
WC
Boger
Dale L
DL
D000465:Algorithms; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004247:DNA / Q000737:chemistry; D004996:Ethidium / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007364:Intercalating Agents / Q000737:chemistry*; D007700:Kinetics; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000032:analysis / Q000737:chemistry*; D013329:Structure-Activity Relationship
D005456:Fluorescent Dyes; D007364:Intercalating Agents; D009841:Oligonucleotides; D004247:DNA; D004996:Ethidium