title: Diagnosis of arterial occlusive disease of the upper extremities: comparison of color duplex sonography and angiography.
abstract: OBJECTIVE
  The aim of this study was to assess the abilities of color duplex sonography (CDUS) to detect and characterize arterial occlusive disease of the upper extremities.
  
  
  METHODS
  We prospectively compared the results of CDUS with those of intra-arterial digital subtraction angiography, which were considered definitive, in patients with symptomatic arterial occlusive disease of the upper extremities. In each extremity, we visualized 9 arterial segments, which were each evaluated for stenoses and occlusions. Each segment was categorized on each imaging modality as not significantly narrowed (narrowed by <50%), significantly narrowed (narrowed by > or =50% but <100%), or occluded (100%).
  
  
  RESULTS
  We examined a total of 578 segments in 57 patients (34 men and 23 women) with a mean age of 50 years (range, 20-74 years). CDUS had a sensitivity, a specificity, a positive predictive value, a negative predictive value, and an accuracy of 98%, 99%, 97%, 99.5%, and 99%, respectively, for detecting occluded lesions and 79%, 100%, 100%, 99%, and 99%, respectively, for detecting hemodynamically significantly stenotic lesions. Notably, the sensitivity of CDUS for diagnosing significantly stenotic lesions (79%) was lower than that for diagnosing occlusive disease (98%).
  
  
  CONCLUSIONS
  With high sensitivity and accuracy rates, CDUS is a reliable screening method for detecting arterial occlusive disease of the upper extremities. This modality efficiently provides anatomic and hemodynamic data that are useful in cases of such disease.
authors.affiliation: Department of Radiology, Türkiye Yüksek Ihtisas Hospital, Kizilay Sokak No 4, Sihhiye 06100, Ankara, Turkey.
authors.forename: Muharrem
authors.initials: M
authors.lastname: Tola
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yurdakul
authors.forename: Sarper
authors.initials: S
authors.lastname: Okten
authors.forename: Ensar
authors.initials: E
authors.lastname: Ozdemir
authors.forename: Turhan
authors.initials: T
authors.lastname: Cumhur
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D001132:Arm / Q000098:blood supply*; D001157:Arterial Occlusive Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color