[The effects of electrostimulation upon soldier's circadian of melatonin in plasma].
Physiological and behavioral rhythms are governed by an endogenous circadian clock. In this paper are reported the studies on soldier's circadian of melatonin concentrations by means of electricity and light pulses presented to the popliteal region (behind the knee). The results showed that the phase of melatonin concentrations can be regulated by both the electricity pulses and the light pulses. A systematic relation was found between the timing of the electro-stimulating and the magnitude and direction of phase shifts, resulting in the generation of a phase response curve. The phase response curve displayed photic model. These findings have implications for the development of more effective treatments for sleep and circadian rhythm disorders.
Jian
Kunlin
K
Institute of Biomedical Engineering, West China Center, Sichuan University, Chengdu 610041. jianman00006@sina.com
Chen
Huaiqing
H
Song
Kaiyuan
K
Sun
Xuechuan
X
Xie
Shuxiong
S
D000293:Adolescent; D000328:Adult; D021081:Chronobiology Disorders / Q000517:prevention & control; D002940:Circadian Rhythm / Q000502:physiology / Q000528:radiation effects*; D004558:Electric Stimulation; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood* / Q000502:physiology; D008889:Military Personnel; D010775:Photic Stimulation; D020178:Sleep Disorders, Circadian Rhythm / Q000517:prevention & control
D008550:Melatonin