Synthesis of thymine-modified oligonucleotides.
Oligonucleotide-resins containing N-nitrothymidine residues yield N3-thymine modified oligonucleotides by reaction with a variety of amines followed by the standard ammonia treatment.
Gorchs
O
O
Departament de Química Orgànica, Universitat de Barcelona, Barcelona, Spain.
Grandas
A
A
Farràs
J
J
D001483:Base Sequence; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis*; D013936:Thymidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
D007202:Indicators and Reagents; C479248:N-nitrothymidine; D009838:Oligodeoxyribonucleotides; D013936:Thymidine