title: Towards a DNA-like duplex without hydrogen bonds.
abstract: The inverse quadrupolar moments of the phenyl and pentafluorophenyl residues in the base pair P-F5 promotes strong intramolecular stacking interactions in DNA duplexes. The more natural base pairs are replaced by this novel pair the higher the thermodynamic stability of the resulting duplex if they are arranged in an alternating fashion.
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland. gerald.mathis@ioc.unibe.ch
authors.forename: Gérald
authors.initials: G
authors.lastname: Mathis
authors.forename: Rolf
authors.initials: R
authors.lastname: Schütz
authors.forename: Jürg
authors.initials: J
authors.lastname: Hunziker
mesh_terms: D002151:Calorimetry; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D009838:Oligodeoxyribonucleotides; D004247:DNA