title: alpha-globin gene deletion and point mutation analysis among in Iranian patients with microcytic hypochromic anemia.
abstract: We tested 67 Iranian individuals, presenting with low mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) levels, normal hemoglobin electrophoresis and iron status, for the presence of twelve common alpha-thalassemia gene deletions and point mutations. Five different mutations (-alpha(3.7), -alpha(4.2), --MED, -(alpha)20.5, Hb Constant Spring) were identified in a total of 43 cases
authors.forename: Masoud
authors.initials: M
authors.lastname: Garshasbi
authors.forename: Christian
authors.initials: C
authors.lastname: Oberkanins
authors.forename: Hai Yang
authors.initials: HY
authors.lastname: Law
authors.forename: Maryam
authors.initials: M
authors.lastname: Neishabury
authors.forename: Roxana
authors.initials: R
authors.lastname: Kariminejad
authors.forename: Hossein
authors.initials: H
authors.lastname: Najmabadi
mesh_terms: D000747:Anemia, Hypochromic / Q000235:genetics*; D004252:DNA Mutational Analysis / Q000379:methods*; D017353:Gene Deletion; D005914:Globins / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D007492:Iran; D017354:Point Mutation / Q000235:genetics*
chemical_list: D005914:Globins