Bacterial vesicle formation as a mechanism of protein transfer to animals.
Gram-negative bacterial vesicle formation is a mechanism for specific secretion and transfer of a protein toxin to animals. This discovery should stimulate work on the mechanism of protein sorting into vesicles and the role of vesicles in bacterial pathogenesis.
Miller
Samuel I
SI
Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Bader
Martin
M
Guina
Tina
T
D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D006460:Hemolysin Proteins; D008561:Membrane Fusion / Q000502:physiology; D021381:Protein Transport / Q000502:physiology; D022161:Transport Vesicles / Q000378:metabolism*
D001426:Bacterial Proteins; D006460:Hemolysin Proteins; C087744:ApxI toxin, Bacteria