title: Multiple cutaneous leiomyomas in the perineum of a horse.
abstract: Multiple cutaneous masses developed in the perineum of a 14-year-old Saddlebred stallion over a period of approximately 5 years. Clinically, the masses ranged in size from 3- to 9-mm diameter and were not ulcerated, painful, or pruritic. Three of the masses were surgically excised and submitted for microscopic evaluation. The masses were dome shaped to nodular, located in the superficial dermis, and composed of haphazardly arranged bundles of plump spindle-shaped cells. The tumor cells immunoreacted with monoclonal antibodies directed against desmin, muscle-specific actin, and smooth muscle actin, confirming a smooth muscle origin. Multiple cutaneous leiomyomas have not been reported previously in horses.
authors.affiliation: Veterinary Diagnostic Laboratory and Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA.
authors.forename: Keith L
authors.initials: KL
authors.lastname: Bailey
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Kinsel
authors.forename: Kathy A
authors.initials: KA
authors.lastname: Connell
mesh_terms: D000818:Animals; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D007889:Leiomyoma / Q000473:pathology* / Q000662:veterinary*; D008297:Male; D010502:Perineum / Q000473:pathology