Influence of food composition on splanchnic blood flow during digestion in unsedated normal dogs: a Doppler study.
The effect of dietary components in gastrointestinal blood flow was investigated non-invasively in dogs. Doppler ultrasound (US) waveform analysis of the celiac artery (CA) and the cranial mesenteric artery (CMA) of eight healthy dogs was performed both in the fasting state and at 20, 40, 60 and 90 min after feeding maintenance, high protein, high carbohydrate and high fat diets. Resistive index (RI), pulsatility index (PI) and the percentage differences between measurements were calculated. In fasted dogs, the CA showed significantly (p<0.05) lower resistance than the CMA. With all diets, post-prandial RI and PI values decreased significantly in both vessels (CA: RI=-12-13%; PI=-25-29%; CMA: RI=-13-15%; PI=-27-29% [p<0.05]), and in all cases significantly earlier in the CA than in the CMA (p<0.05). With all diets except high fat the maximum decrease in RI and PI was reached in the CA at 40 min and in the CMA at 60 min. High fat diets were unique in that the maximum decrease in RI and PI in the CMA occurred earlier (at 20 min) and values were slower to return to normal (p<0.05). We conclude that Doppler US can be used in dogs to quantify significant differences in the response of splanchnic blood flow to different dietary components.
Kircher
P
P
Division of Clinical Radiology, Department of Clinical Veterinary Medicine, University of Berne, Laenggassstrasse 128, 3012 Berne, Switzerland. patrick.kircher@knp.unibe.ch
Lang
J
J
Blum
J
J
Gaschen
F
F
Doherr
M
M
Sieber
C
C
Gaschen
L
L
D000818:Animals; D001783:Blood Flow Velocity / Q000662:veterinary; D002445:Celiac Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004032:Diet / Q000662:veterinary*; D004040:Dietary Carbohydrates / Q000378:metabolism; D004041:Dietary Fats / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism; D004064:Digestive System / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000378:metabolism*; D004285:Dogs / Q000378:metabolism*; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging / Q000502:physiology; D013152:Splanchnic Circulation / Q000502:physiology*; D018615:Ultrasonography, Doppler, Color / Q000662:veterinary
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins