[Study on purification of glycyrrhizic acid with macroporous adsorption resin].
OBJECTIVE
To study the adsorption and desorption behavior of macroporous adsorbption resin AB-8 for glycyrrhizic acid and its effect factors.


METHODS
The optimum purification conditions were investigated by high performance liquid chromatography and the orthogonal experiments.


RESULTS
The optimum conditions were as follows: the flow rate at 1 ml/min, pH at 6.4-7.4 and the solution concentration at 10 mg/ml.


CONCLUSIONS
AB-8 had a high adsorption capacity for glycyrrizic acid and elution was easy.
Liu
Qian
Q
Jiangsu University, Zhenjiang 212013.
Yang
Liuqing
L
Wu
Xiangyang
X
Chen
Jun
J
D000327:Adsorption; D000837:Anion Exchange Resins; D002851:Chromatography, High Pressure Liquid; D029882:Glycyrrhiza uralensis / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000837:Anion Exchange Resins; D019695:Glycyrrhizic Acid