title: Bi- and tricyclic nucleoside derivatives restricted in S-type conformations and obtained by RCM-reactions.
abstract: Ring-closing metathesis (RCM) is applied as a new and powerful technology in the construction of nucleoside analogues that are conformationally restricted in S-type conformations due to additional 3',4'- and/or 3',5'-linkages.
authors.affiliation: Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
authors.forename: Nanna
authors.initials: N
authors.lastname: Albaek
authors.forename: Jacob
authors.initials: J
authors.lastname: Ravn
authors.forename: Morten
authors.initials: M
authors.lastname: Freitag
authors.forename: Helena
authors.initials: H
authors.lastname: Thomasen
authors.forename: Nanna K
authors.initials: NK
authors.lastname: Christensen
authors.forename: Michael
authors.initials: M
authors.lastname: Petersen
authors.forename: Poul
authors.initials: P
authors.lastname: Nielsen
mesh_terms: D002625:Chemistry, Organic / Q000379:methods; D008958:Models, Molecular; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D009705:Nucleosides