title: Detrusor resistive index evaluated by Doppler ultrasonography as a potential indicator of bladder outlet obstruction.
abstract: OBJECTIVE
  To appraise detrusor blood flow by Doppler ultrasonography in men with suspected bladder outlet obstruction (BOO) to determine whether this imaging technique provides useful information for the assessment of BOO. Experimental studies have shown that BOO is associated with reduced blood flow to the detrusor.
  
  
  METHODS
  Twenty-nine consecutive men with lower urinary tract symptoms were prospectively enrolled. A urodynamic pressure-flow study was performed by the urologist to determine BOO, and Doppler ultrasonography was subsequently performed by the radiologist. The physicians were unaware of the other's results. Scanning was performed on a filled and empty bladder. Arterial blood flow was measured at three distinct sites, the two lateral walls and the trigone, and the resistive index (RI) of each site was calculated (RI = (V(MAX) - V(MIN))/V(MAX)). For each patient, the arithmetic average of the three RIs was defined as the detrusor RI. The findings were compared between patients with and without evidence of BOO. A logistic regression model tested the predictive value of the RI.
  
  
  RESULTS
  According to the pressure-flow study results, 22 (75%) and 7 (25%) of the 29 patients were diagnosed as having or not having BOO, respectively. A statistically significant difference was found between the detrusor RI in the obstructed versus nonobstructed patients in both full (P <0.001) and empty (P <0.03) bladder states (0.79 versus 0.68 and 0.74 versus 0.66, respectively). Our logistic regression model predicted BOO with an overall accuracy of 86%, positive predictive value of 95%, and negative predictive value of 57%.
  
  
  CONCLUSIONS
  The RI of arterial blood flow in the detrusor measured by Doppler ultrasonography provides important predictive information for the presence of BOO. Additional studies are warranted to validate our results and explore the role of Doppler ultrasonography in the management paradigms of patients with suspected BOO.
authors.affiliation: Department of Radiology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Belenky
authors.forename: Y
authors.initials: Y
authors.lastname: Abarbanel
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.forename: O
authors.initials: O
authors.lastname: Yossepowitch
authors.forename: P M
authors.initials: PM
authors.lastname: Livne
authors.forename: G N
authors.initials: GN
authors.lastname: Bachar
mesh_terms: D000368:Aged; D015331:Cohort Studies; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000098:blood supply; D010865:Pilot Projects; D011446:Prospective Studies; D012039:Regional Blood Flow; D018615:Ultrasonography, Doppler, Color; D001743:Urinary Bladder / Q000000981:diagnostic imaging; D001748:Urinary Bladder Neck Obstruction / Q000000981:diagnostic imaging*; D014563:Urodynamics