title: Hydatid disease of bone. Review of 11 cases.
abstract: Osseous hydatid disease is defined as development within bone of multiple cysts that are the larval form of the tapeworm Echinococcus granulosus. Bone cysts account for only 0.5-2.5% of all hydatid cysts in humans. We report on our experience.
  
  
  METHODS
  This retrospective study included patients managed between 1988 and 1998 for histologically documented hydatid disease of bone.
  
  
  RESULTS
  Eleven patients were included, six men and five women, with a mean age of 40.7 +/- 11.04 years (range, 27-60 years). Mean time to diagnosis was 22.7 +/- 18.2 months (range, 5-36). The pelvis was involved in six patients and a long bone in five (the femur in three, the tibia in one, and the fibula in one). Peripheral eosinophil counts were high in four patients and serological tests for hydatid disease were positive in five patients. Surgical treatment was used alone in 10 patients and with albendazole in one patient. The main complications were fistulization (n = 6) and suppuration (n = 4). Five patients experienced recurrences.
  
  
  CONCLUSIONS
  Hydatid disease still occurs in Morocco. The liver and lungs are the most common targets. Bone cysts are uncommon but severe. The behavior of osseous hydatid cysts resembles that of locally malignant lesions. Although immunofluorescent assays are useful, the final diagnosis depends on histology. The treatment rests on surgical excision. Recurrence is common, particularly at sites that are difficult to access.
authors.affiliation: Rheumatology Department A, El Ayachi Hospital, Salé, Morocco. houyam2000@yahoo.com
authors.forename: Houyam
authors.initials: H
authors.lastname: Loudiye
authors.forename: Souad
authors.initials: S
authors.lastname: Aktaou
authors.forename: Hasna
authors.initials: H
authors.lastname: Hassikou
authors.forename: Ahmed
authors.initials: A
authors.lastname: El-Bardouni
authors.forename: Mohamed
authors.initials: M
authors.lastname: El-Manouar
authors.forename: Mohamed
authors.initials: M
authors.lastname: Fizazi
authors.forename: Abdelhakim
authors.initials: A
authors.lastname: Tazi
authors.forename: Najia
authors.initials: N
authors.lastname: Hajjaj-Hassouni
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000923:Anticestodal Agents / Q000627:therapeutic use; D001850:Bone Diseases, Infectious / Q000188:drug therapy / Q000469:parasitology* / Q000601:surgery*; D004443:Echinococcosis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000923:Anticestodal Agents; D015766:Albendazole