title: UK laboratory intercomparison on internal dosimetry.
abstract: A laboratory intercomparison for internal dose assessment from a variety of intake scenarios is described. This is the first UK intercomparison using the revised ICRP Human Respiratory Tract and biokinetic models. Four United Kingdom laboratories participated and six cases were assessed. Overall, the agreement in internal dose assessments between laboratories was considered satisfactory with 79% of the assessed committed effective doses, e(50), for cases within a band of +/- 40% of the median value. The range (highest/lowest) in e(50) estimated by the laboratories was smallest (1.2) for a case involving inhalation of 137Cs. The range was greatest (6.0) for a case involving a wound with, and possible inhalation of, 238Pu, 239Pu and 241Am; the variation between laboratories in assessment of intakes could not be considered to be satisfactory in this case. Judgements on the most appropriate data to use in estimating intakes, choice of parameter values for use with the ICRP models and allowing for the effects of treatment with DTPA were important sources of variability between laboratories.
authors.affiliation: AWE, Aldermaston, Berks, UK.
authors.forename: J
authors.initials: J
authors.lastname: Speed
authors.forename: A
authors.initials: A
authors.lastname: Birchall
authors.forename: R
authors.initials: R
authors.lastname: Bull
authors.forename: R
authors.initials: R
authors.lastname: Cockerill
authors.forename: N S
authors.initials: NS
authors.lastname: Jarvis
authors.forename: J W
authors.initials: JW
authors.lastname: Marsh
authors.forename: M S
authors.initials: MS
authors.lastname: Peace
authors.forename: G
authors.initials: G
authors.lastname: Roberts
authors.forename: C
authors.initials: C
authors.lastname: Scarlett
authors.forename: D
authors.initials: D
authors.lastname: Spencer
authors.forename: P
authors.initials: P
authors.lastname: Stewart
mesh_terms: D001822:Body Burden; D006283:Health Physics / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007753:Laboratories / Q000592:standards; D015588:Observer Variation; D016273:Occupational Exposure / Q000032:analysis; D011785:Quality Assurance, Health Care / Q000379:methods / Q000592:standards; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods* / Q000592:standards*; D018788:Radioactive Hazard Release; D011868:Radioisotopes / Q000032:analysis*; D011874:Radiometry / Q000379:methods* / Q000592:standards; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods / Q000592:standards; D017751:Safety Management / Q000379:methods* / Q000592:standards*; D012680:Sensitivity and Specificity; D006113:United Kingdom
chemical_list: D011868:Radioisotopes