Congenital bilateral adductor vocal cord paralysis.
Bilateral adductor vocal cord paralysis (BAdP), presenting with features of laryngeal incompetence, is a rare form of congenital bilateral vocal cord paralysis, and only 2 small series of BAdP have previously been published. Three cases are reported here. The BAdP occurred as an isolated abnormality in 1 child, and was associated with a recognizable syndrome (Robinow's syndrome and 22q deletion) in the other 2 children. Gastrostomy tube feeding was required in 2 children, who both remain gastrostomy tube-dependent at 26 months and 10 years 9 months of age. The child with Robinow's syndrome received parenteral nutrition until 2 months, but was then able to feed orally after partial improvement in vocal cord function. The global impairment in vocal cord constrictor function observed in these 3 children is consistent with the site of lesion's being at the level of the laryngeal constrictor motoneurons in BAdP.
Berkowitz
Robert G
RG
Dept of Otolaryngology, Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
D002892:Chromosomes, Human, Pair 22 / Q000235:genetics*; D019465:Craniofacial Abnormalities / Q000150:complications*; D004392:Dwarfism / Q000150:complications*; D004750:Enteral Nutrition; D005260:Female; D005774:Gastrostomy; D017353:Gene Deletion; D006801:Humans; D007231:Infant, Newborn; D007818:Laryngeal Diseases / Q000209:etiology; D008297:Male; D010288:Parenteral Nutrition; D012189:Retrospective Studies; D013577:Syndrome; D014826:Vocal Cord Paralysis / Q000150:complications* / Q000235:genetics* / Q000628:therapy