title: [Avoid purine-rich foods, drink a lot, reduce weight. The most important recipes against hyperuricemia].
abstract: In 99% of the cases, the underlying cause of gout is an inborn disorder of uric acid excretion. In addition to acute arthritis, clinical consequences include tophi, chronic destruction of joints, and ulcers. The patient is endangered by the frequent renal involvement, with hypertension and renal insufficiency. Furthered by such exogenous factors as overweight, high-calorie, purine-rich foods and immoderate consumption of alcohol, hyperuricemia may develop. Basic treatment comprises dietary measures and, up to a serum uric acid concentration of 8.5 mg/dl, should be the sole measure required. The aim is to achieve a permanent lowering of uric acid concentrations in the blood to < 6.5 mg/dl. This may be achieved by reduction of overweight (including regular exercise), an energy-adapted diet with only moderate amounts of fat, restriction--or, better, banishment--of alcohol, an ovolactovegetarian diet low in purine (care must be taken with high-purine vegetablesl), moderate intake of readily assimilated carbohydrates, and adequate amounts of calorie-free liquids.
authors.affiliation: monika.benecke@quetheb.de
authors.forename: Monika
authors.initials: M
authors.lastname: Benecke
mesh_terms: D000428:Alcohol Drinking; D004032:Diet; D004326:Drinking; D015444:Exercise; D005502:Food; D006073:Gout / Q000517:prevention & control / Q000628:therapy; D006801:Humans; D033461:Hyperuricemia / Q000517:prevention & control* / Q000628:therapy; D014527:Uric Acid / Q000032:analysis; D015431:Weight Loss
chemical_list: D014527:Uric Acid