title: Role of CT venography in the diagnosis and treatment of benign thoracic central venous obstruction.
abstract: OBJECTIVE
  To evaluate the role of CT venography in the diagnosis and treatment of benign thoracic central venous obstruction.
  
  
  METHODS
  Eighteen patients who had undergone both CT venography and digital subtraction venography were prospectively enrolled in this study. The following features were analyzed by two observers: the cause, degree, and extent of venous obstruction; associated thrombosis; and implications for the planning of treatment. CT venography and digital subtraction venography were compared in defined venous segments, and the degree of obstruction, and correlation was expressed using Spearman's rank correlation coefficient.
  
  
  RESULTS
  In all patients, CT venography depicted the causes of obstruction, including extrinsic compression of the left brachiocephalic vein, and mediastinal inflammatory pseudotumor. Interobserver agreement regarding classification of the degree of obstruction was judged as good for CT venography (K=0.864), and in evaluating this, there was significant correlation between CT venography and digital subtraction venography (reader 1: Rs = 0.58, p < 0.01; reader 2: Rs = 0.56, p < 0.01). In evaluating the status of central veins proximal to long segmental obstruction, and associated thrombosis, CT venography was superior to digital subtraction venography. In half of all patients, the findings of CT venography led to changes in the treatment plan.
  
  
  CONCLUSIONS
  The findings of CT venography correlated closely with those of digital subtraction venography, and the former accurately depicted the degree and extent of benign venous obstruction.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul, Korea. chungjw@radcom.snu.ac.kr
authors.forename: Hyo- Cheol
authors.initials: H
authors.lastname: Kim
authors.forename: Jin Wook
authors.initials: JW
authors.lastname: Chung
authors.forename: Jae Hyung
authors.initials: JH
authors.lastname: Park
authors.forename: Yong Hu
authors.initials: YH
authors.lastname: Yin
authors.forename: Seong Ho
authors.initials: SH
authors.lastname: Park
authors.forename: Chang Jin
authors.initials: CJ
authors.lastname: Yoon
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Choi
mesh_terms: D015901:Angiography, Digital Subtraction; D002405:Catheterization, Central Venous / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000000981:diagnostic imaging*; D020246:Venous Thrombosis / Q000000981:diagnostic imaging*