Recent progress towards the identification of inhibitors of mycobacterial cell wall polysaccharide biosynthesis.
Mycobacterial infections have recently attracted significant attention from international health agencies due to the resurgence of these diseases worldwide. This review summarizes the recent work directed towards the identification of new anti-tuberculosis agents that act by inhibiting mycobacterial cell wall polysaccharide biosynthesis.
Lowary
Todd L
TL
Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, USA. lowary.2@osu.edu
D002240:Carbohydrate Sequence; D002473:Cell Wall / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D005685:Galactans / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008969:Molecular Sequence Data; D009161:Mycobacterium / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D011134:Polysaccharides / Q000037:antagonists & inhibitors* / Q000096:biosynthesis*
D005685:Galactans; D011134:Polysaccharides; C030080:araban