title: Chemopersistent early recurrence in the perineal tear scar of an intrapartally diagnosed cervical cancer.
abstract: BACKGROUND
  Cervical cancer is the most frequent cancer occurring in pregnancy. Apart from some general recommendations, there is no standardized consensus for the management of this cancer during pregnancy. Individual case reports do exist on intrapartal cancer diagnosis and risks.
  
  
  METHODS
  We describe the case of an early recurrence in the perineal tear scar of an intrapartally diagnosed cervical cancer, which had developed despite combined neoadjuvant and adjuvant chemotherapy.
  
  
  CONCLUSIONS
  Although iatrogenic tumor cell spreading in the vagina is rare, this oncological risk is easy to avoid. It should be considered in the peripartal management of patients suffering from cervical cancer. Our case report underlines the limits of chemotherapy in the treatment of tumor residue and points out the problem of cervical cancer cell spreading during invasive procedures.
authors.affiliation: Department of Gynecology and Obstetrics, University of Cologne, 50924, Cologne, Germany. nc-hoopmama@netcologne.de
authors.forename: Markus
authors.initials: M
authors.lastname: Hoopmann
authors.forename: Markus
authors.initials: M
authors.lastname: Valter
authors.forename: Christian
authors.initials: C
authors.lastname: Kurbacher
authors.forename: Marc
authors.initials: M
authors.lastname: Possover
authors.forename: Peter K
authors.initials: PK
authors.lastname: Mallmann
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000473:pathology*; D010502:Perineum / Q000293:injuries* / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology*