Aryldiazomethane derivatives as reagents for site specific labeling of nucleic acids at phosphate.
An efficient and direct labeling method based on direct alkylation of nucleic acids at phosphates by aryldiazomethane derivatives is described.
Bourget
Cécile
C
Université Joseph Fourier, LEDSS-UMR5616 associé au CNRS, Grenoble, France.
Trévisiol
Emmanuelle
E
Lhomme
Jean
J
Kotera
Mitsuharu
M
Tora
Christelle
C
Bernal-Mendez
Eloy
E
Laayoun
Ali
A
D000478:Alkylation; D001665:Binding Sites; D004247:DNA / Q000737:chemistry*; D003978:Diazomethane / Q000031:analogs & derivatives* / Q000737:chemistry; D020411:Oligonucleotide Array Sequence Analysis; D012680:Sensitivity and Specificity
D003978:Diazomethane; D004247:DNA