Medical management of a cervical pregnancy: a case report.
BACKGROUND
Cervical pregnancy is a rare condition that can become life-threatening if heavy bleeding occurs.


METHODS
Grace (pseudonym) is a 32-year-old woman who was admitted to hospital at approximately 6 weeks' gestational age after several days of heavy bleeding. Ultrasonographic examination revealed the presence of cervical pregnancy. She received multiple doses of methotrexate with folinic acid rescue, and did not require surgical intervention. Nine months after the resolution of the cervical pregnancy, Grace again became pregnant. She had an uncomplicated gestation and a normal vaginal delivery of a healthy baby at term.


CONCLUSIONS
Multiple-dose methotrexate with folinic acid rescue was a safe option for the medical treatment of ectopic cervical pregnancy in this case. Long-term toxicity studies and case reports are required to provide more information regarding safety and for clinicians to individualize treatment regimens.
Gianetto-Berruti
Alessandra
A
Department of Obstetrics and Gynaecology, University of Western Ontario, London, ON, Canada.
Feyles
Valter
V
Mohide
Patrick T
PT
D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000150:complications / Q000188:drug therapy*; D012449:Safety; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000209:etiology
D000020:Abortifacient Agents, Nonsteroidal; D002955:Leucovorin; D008727:Methotrexate