title: Amyloidosis in macaques in adler primatological center.
abstract: Results of pathomorphological studies of 133 amyloidosis cases in macaques of 3 species (M. mulatta, M. nemestrina, and M. fascicularis) in the Adler Primatological Center are presented. A relationship between the development of amyloidosis and animal age is detected and the incidence of involvement of various organs is determined. Generalized and isolated forms of amyloidosis are described, the most incident of which (36.8%) was hepatic amyloidosis. Simian and human amyloidosis are compared. Amyloidosis in macaques can be used as the model process for studies of amyloidosis in humans.
authors.affiliation: Institute of Medical Primatology, Russian Academy of Medical Sciences, Sochi-Adler.
authors.forename: E S
authors.initials: ES
authors.lastname: Naumenko
authors.forename: R I
authors.initials: RI
authors.lastname: Krylova
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology*; D000818:Animals; D004396:Coloring Agents / Q000494:pharmacology; D003224:Congo Red / Q000494:pharmacology; D006801:Humans; D008099:Liver / Q000378:metabolism; D008251:Macaca; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008254:Macaca nemestrina; D008992:Monkey Diseases; D013045:Species Specificity
chemical_list: D004396:Coloring Agents; D003224:Congo Red