Does it take two to untangle?
The structural integrity of mitotic chromosomes is essential for proper chromatid segregation. In this issue of Cell, show that vertebrates contain two distinct condensin complexes, both of which are required for normal mitotic chromosome morphology.
Bertsch
Denise N
DN
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Lindsley
Janet E
JE
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D002842:Chromatids / Q000378:metabolism* / Q000648:ultrastructure; D020090:Chromosome Segregation; D002875:Chromosomes / Q000378:metabolism* / Q000648:ultrastructure; D004268:DNA-Binding Proteins / Q000378:metabolism*; D006801:Humans; D046911:Macromolecular Substances; D046912:Multiprotein Complexes
D004268:DNA-Binding Proteins; D046911:Macromolecular Substances; D046912:Multiprotein Complexes; C108312:condensin complexes; D000251:Adenosine Triphosphatases