Techniques: magnetic resonance imaging of the lung provides potential for non-invasive preclinical evaluation of drugs.
Beckmann
Nicolau
N
Discovery Technologies Center, Novartis Institutes for BioMedical Research, Lichtstrasse 35, WSJ-386.2.09, CH-4002 Basel, Switzerland. nicolau.beckmann@pharma.novartis.com
Tigani
Bruno
B
Mazzoni
Lazzaro
L
Fozard
John R
JR
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D015507:Drugs, Investigational / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive; D051381:Rats
D000893:Anti-Inflammatory Agents; D015507:Drugs, Investigational