title: N-3 substituted TSAO derivatives as a probe to explore the dimeric interface of HIV-1 reverse transcriptase.
authors.affiliation: Instituto de Química Médica (C.S.I.C.), Madrid, Spain.
authors.forename: María-Cruz
authors.initials: MC
authors.lastname: Bonache
authors.forename: Cristina
authors.initials: C
authors.lastname: Chamorro
authors.forename: Sonsoles
authors.initials: S
authors.lastname: Velázquez
authors.forename: Erik
authors.initials: E
authors.lastname: De Clercq
authors.forename: Jan
authors.initials: J
authors.lastname: Balzarini
authors.forename: María-José
authors.initials: MJ
authors.lastname: Camarasa
authors.forename: Ana
authors.initials: A
authors.lastname: San-Félix
mesh_terms: D001665:Binding Sites; D019281:Dimerization; D054303:HIV Reverse Transcriptase / Q000378:metabolism*; D015497:HIV-1 / Q000502:physiology*; D008958:Models, Molecular; D015394:Molecular Structure; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D013141:Spiro Compounds / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013936:Thymidine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D014529:Uridine / Q000031:analogs & derivatives; D014779:Virus Replication / Q000187:drug effects
chemical_list: D018894:Reverse Transcriptase Inhibitors; D013141:Spiro Compounds; C072416:reverse transcriptase, Human immunodeficiency virus 2; D054303:HIV Reverse Transcriptase; D012194:RNA-Directed DNA Polymerase; D013936:Thymidine; C075132:TSAO-T; D014529:Uridine