title: T-wave alternans in patients with right ventricular tachycardia.
abstract: Microvolt T-wave alternans has been proposed as a new risk marker for ventricular arrhythmias. However, the clinical significance of T-wave alternans in patients with ventricular tachycardia (VT) originating from the right ventricle has been unknown. The study population consisted of 20 patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) or idiopathic VT. T-wave alternans was measured during bicycle exercise testing using the CH 2000 system. Of the 7 patients with ARVC, 6 (86%) were positive for T-wave alternans. On the other hand, only 1 (8%) of 13 patients with idiopathic VT originating from the right-ventricular outflow tract was positive for T-wave alternans.
authors.affiliation: First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. kinos@hsp.md.shinshu-u.ac.jp
authors.forename: Osamu
authors.initials: O
authors.lastname: Kinoshita
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tomita
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hanaoka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsutsui
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Yazaki
authors.forename: Noboru
authors.initials: N
authors.lastname: Watanabe
authors.forename: Minoru
authors.initials: M
authors.lastname: Hongo
authors.forename: Keishi
authors.initials: K
authors.lastname: Kubo
mesh_terms: D017667:Adipocytes / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000175:diagnosis / Q000209:etiology / Q000401:mortality; D001706:Biopsy; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000209:etiology / Q000401:mortality; D006328:Cardiac Catheterization; D004452:Echocardiography; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D004719:Endomyocardial Fibrosis / Q000175:diagnosis / Q000209:etiology / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000166:cytology / Q000473:pathology; D012720:Severity of Illness Index; D016019:Survival Analysis; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality