Multidrug-resistant tuberculosis in a lung transplant recipient.
Tuberculosis infection has been a relatively rare complication after lung transplantation. However, as more countries in which Mycobacterium tuberculosis infection remains endemic embark on lung transplant programs, the occurrence of multidrug-resistant tuberculosis after transplantation is a genuine threat. We report the first case of multidrug-resistant tuberculosis in a double-lung transplant recipient who probably acquired the disease from the donor. We discuss the problems in clinical management of post-transplant tuberculosis infection and of drug-resistance.
Lee
Joseph
J
Tuberculosis and Chest Unit, Grantham Hospital, 125 Wong Chuk Hang Road, Aberdeen, Hong Kong SAR, China. josephlee59@yahoo.com
Yew
Wing Wai
WW
Wong
Chi Fong
CF
Wong
Poon Chuen
PC
Chiu
Clement Shui Wah
CS
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016040:Lung Transplantation; D011859:Radiography; D014019:Tissue Donors; D018088:Tuberculosis, Multidrug-Resistant / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission
D000995:Antitubercular Agents; D007166:Immunosuppressive Agents