Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change.
Bae
Younsoo
Y
Department of Material Science and Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Fukushima
Shigeto
S
Harada
Atsushi
A
Kataoka
Kazunori
K
D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D004317:Doxorubicin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008823:Micelles; D011108:Polymers / Q000737:chemistry*; D013997:Time Factors
D008823:Micelles; D011108:Polymers; D004317:Doxorubicin