Zero tolerance for nonsense: nonsense-mediated mRNA decay uses multiple degradation pathways.
Wormington
Michael
M
Department of Biology, University of Virginia, Charlottesville, VA 22903, USA.
D000818:Animals; D018389:Codon, Nonsense / Q000235:genetics*; D004722:Endoribonucleases / Q000502:physiology; D005057:Eukaryotic Cells / Q000378:metabolism*; D005095:Exoribonucleases / Q000502:physiology; D063326:Exosome Multienzyme Ribonuclease Complex; D006801:Humans; D046911:Macromolecular Substances; D009687:Nuclear Proteins / Q000502:physiology; D020871:RNA Stability / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*
D018389:Codon, Nonsense; D004722:Endoribonucleases; D005095:Exoribonucleases; D063326:Exosome Multienzyme Ribonuclease Complex; D046911:Macromolecular Substances; D009687:Nuclear Proteins; D012333:RNA, Messenger; C077044:EXOSC10 protein, human; C467723:DCP2 protein, human