title: Apraxia of eyelid opening in a case of atypical corticobasal degeneration.
abstract: Apraxia of eyelid opening (AEO) occurs in several clinical conditions, even in the absence of any other neurological sign; nonetheless, in most of the cases AEO has been reported in association with basal ganglia diseases, such as corticobasal degeneration (CBD). We describe a patient with a clinical diagnosis of frontotemporal dementia who, later, developed parkinsonian signs and AEO. We suggest that the finding of AEO in patients with a frontotemporal syndrome could be a helpful expedient for the early diagnosis of atypical clinical findings of CBD, characterised by behavioural and cognitive aspects at first.
authors.affiliation: Dipartimento di Scienze Neurologiche, Università La Sapienza, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Sepe-Monti
authors.forename: F
authors.initials: F
authors.lastname: Giubilei
authors.forename: F
authors.initials: F
authors.lastname: Marchione
authors.forename: C
authors.initials: C
authors.lastname: Colosimo
mesh_terms: D001479:Basal Ganglia / Q000503:physiopathology; D001480:Basal Ganglia Diseases / Q000175:diagnosis*; D003704:Dementia / Q000503:physiopathology; D005141:Eyelid Diseases / Q000503:physiopathology*; D005143:Eyelids / Q000503:physiopathology; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009410:Nerve Degeneration / Q000503:physiopathology; D019636:Neurodegenerative Diseases / Q000175:diagnosis*; D010302:Parkinson Disease, Secondary / Q000503:physiopathology*; D013702:Temporal Lobe / Q000503:physiopathology