title: Practical synthesis of D-cyclopent-2-enone, the key intermediate of carbocyclic nucleosides.
abstract: An efficient and practical method for the synthesis of (4R,5R)-4,5-O-isopropylidene-cyclopent-2-enone was developed from D-ribose by using a ring-closing metathesis reaction.
authors.affiliation: Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, The University of Georgia, Athens, Georgia 30602-2352, USA.
authors.forename: Y H
authors.initials: YH
authors.lastname: Jin
authors.forename: C K
authors.initials: CK
authors.lastname: Chu
mesh_terms: D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D008958:Models, Molecular; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C479169:(4R,5R)-4,5-O-isopropylidene-cyclopent-2-enone; D003517:Cyclopentanes; D007202:Indicators and Reagents; D009705:Nucleosides