title: Applied introduction to multivariate methods used in drug discovery.
abstract: The number of articles concerning optimization and applications of multivariate techniques in drug discovery testifies the growing importance attributed to these methods. This mini review focuses on some of the basic and most employed multivariate techniques in drug discovery research. Examples from the literature were selected to illustrate a number of potential applications.
authors.affiliation: NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research, Bioinformatics Core Facility, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland. eugenia.migliavacca@isrec.unil.ch
authors.forename: Eugenia
authors.initials: E
authors.lastname: Migliavacca
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry; D001812:Blood-Brain Barrier / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D015195:Drug Design; D015999:Multivariate Analysis; D004364:Pharmaceutical Preparations / Q000737:chemistry; D012107:Research Design
chemical_list: D000970:Antineoplastic Agents; D004364:Pharmaceutical Preparations