Seventy-two cases of antidiabetic-induced hepatopathy treated by huatan yigan decoction.
In order to observe the therapeutic effects of Huatan Yigan Decoction ([symbol: see text] Decoction for resolving phlegm and replenishing the liver) on antidiabetic-induced hepatopathy, 129 cases were divided into two groups, 72 cases in the treatment group were administrated with Huatan Yigan Decoction and 57 cases in the control group with the liver-protecting drugs. Their liver function, plasma prothrombin time (PT), blood urea nitrogen and symptoms of the patients before and after treatment were observed during the three therapeutic courses.


RESULTS
The total effective rate and cured rate of the treatment group manifested an obvious difference in comparison with those of the control group (P < 0.05 or P < 0.01). Even though the liver function, blood urea nitrogen (BUN) and symptoms in both groups were improved markedly, these indicators in the treatment group were improved more markedly than those in control group (P < 0.01). No adverse effect was found during the treatment.


CONCLUSIONS
Huatan Yigan Decoction shows a repair action on hepatic injury.
Hu
Yonghe
Y
Department of Endocrine, First Hospital, Tianjin College of Traditional Chinese Medicine, Tianjin 300193.
Li
Jing
J
Zhou
Jing
J
D000328:Adult; D000368:Aged; D001806:Blood Urea Nitrogen; D056486:Chemical and Drug Induced Liver Injury; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008107:Liver Diseases / Q000188:drug therapy*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents