Synthesis of some N-galactosides of 3-aryl-5-benzyl (or substituted benzyl)-1,2,4-triazin-6(1H)-/ones or thiones of expected biological activity.
The 1-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-3-aryl-5-benzyl (or substituted benzyl)-1,2,4-triazin-6(1H)-/ones or thiones were prepared via galactosidation of 3-aryl-5-benzyl (or substituted benzyl)-1,2,4-triazin-6(1H)-/ones or thiones with 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl bromide. The structure of the new galactosyl derivatives was based on both spectroscopic and chemical evidences.
Mansour
Abdel Kader
AK
Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt.
Eid
Mohga M
MM
Khalil
Nasser S A M
NS
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D005697:Galactosides / Q000737:chemistry*; D015394:Molecular Structure; D014227:Triazines / Q000138:chemical synthesis*
D000970:Antineoplastic Agents; D005697:Galactosides; D014227:Triazines