Isolation and structure determination of a benzofuran and a bis-nor-isoprenoid from Aspergillus niger grown on the water soluble fraction of Morinda citrifolia Linn. leaves.
The leaves of Morinda citrifolia, Linn. afforded a new benzofuran and a bis-nor-isoprenoid, blumenol C, hitherto unreported from this source. The structures of these have been elucidated as 5-benzofuran carboxylic acid-6-formyl methyl ester (1) and 4-(3'(R)-hydroxybutyl)-3,5,5, trimethyl-cyclohex-2-en-1-one (2) respectively through spectroscopic studies. The NMR data (including 1D, 2D techniques) and stereochemistry at C-3' of Compound 2 is also being reported for the first time.
Siddiqui
Bina S
BS
H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. bina@khi.comsats.net.pk
Ismail
Fouzia A Sattar
FA
Gulzar
Tahsin
T
Begum
Sabira
S
D001234:Aspergillus niger / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification*; D003470:Culture Media; D003510:Cyclohexanes / Q000737:chemistry / Q000302:isolation & purification*; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D032066:Morinda / Q000737:chemistry; D010936:Plant Extracts; D012995:Solubility
C478848:4-(3'(R)-hydroxybutyl)-3,5,5, trimethyl-cyclohex-2-en-1-one; C478847:5-benzofuran carboxylic acid-6-formyl methyl ester; D001572:Benzofurans; D003470:Culture Media; D003510:Cyclohexanes; D004952:Esters; D010936:Plant Extracts