Stereospecific hydroxylation of (+)-cedrol by using human skin microbial flora Staphylococcus epidermidis.
Microbial transformation of (+)-cedrol was investigated by using Staphylococcus epidermidis and found that stereospecific hydroxylation of (+)-cedrol occurred at the C-3 position to form (+)-(3S)-3-hydroxycedrol.
Miyazawa
Mitsuo
M
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3-4-1, Kowakae, Higashiosaka-shi, Osaka 577-8502, Japan. miyazawa@apch.kindai.ac.jp
Itsuzaki
Yumi
Y
Ishikawa
Keiji
K
Ishisaka
Kaname
K
D001711:Biotransformation; D006801:Humans; D006900:Hydroxylation; D008968:Molecular Conformation; D000081223:Polycyclic Sesquiterpenes; D012867:Skin / Q000382:microbiology; D013212:Staphylococcus epidermidis / Q000201:enzymology*; D013729:Terpenes / Q000378:metabolism*
D000081223:Polycyclic Sesquiterpenes; D013729:Terpenes; C078669:cedrol