[Hemophagocytosis associated with an Escherichia coli sepsis: a case report].
BACKGROUND
Hemophagocytic lymphohistiocytosis syndrome (HLS) is defined by activated macrophage proliferation. These cells phagocyte the blood elements. This syndrome can be primary as an autosomal recessive disease or secondary to neoplasia, immune diseases or infections-viral, parasitary or bacterian.


METHODS
Our case concerns an association of HLS and Escherichia coli (E. coli) sepsis in a metastatic prostatic cancer. The evolution was rapidly improved by antibiotics alone. The clinical and biological aspects as well as the differential diagnosis are discussed.


CONCLUSIONS
The HLS is fatal. It can be caused by a severe infection, even an E. coli sepsis. The treatment focused on etiology can be sufficient.
El Khoury
N
N
Service de néphrologie A et de réanimation, hôpital Tenon, 4, rue de la Chine, 75970 Paris cedex 20, France. nkhoury09@yahoo.fr
Lassoued
K
K
Pellé
G
G
Foucher
A
A
Costa
M-A
MA
Rondeau
E
E
Sraer
J-D
JD
D000368:Aged; D016470:Bacteremia / Q000150:complications*; D004927:Escherichia coli Infections / Q000150:complications*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology*; D006801:Humans; D008262:Macrophage Activation; D008297:Male; D013577:Syndrome