Serum ferritin levels in poorly- and well-controlled diabetes mellitus.
Serum ferritin level is related to body iron stores and is influenced by several diseases. We aimed to evaluate the association between serum ferritin concentration and the complications and nature of diabetes mellitus (DM). We examined association of ferritin concentration, fasting and post-prandial glucose levels and glycated hemoglobin in 329 patients with type 2 diabetes mellitus and 269 healthy controls. In the present study, 41 of 150 poorly controlled diabetic patients and 31 of 119 cases had hyperferritinemia. We confirmed that serum ferritin was increased in diabetic patients as long as glycemic control is not achieved. There was also a correlation between ferritin level and diabetic retinopathy. In conclusion, this study showed an independent positive association between serum ferritin concentration and markers of glucose homeostasis.
Canturk
Zeynep
Z
Department of Endocrinology and Metabolism, Kocaeli University, Medical School, Derince, Kocaeli, Turkey. canturkz@yahoo.com
Cetinarslan
Berrin
B
Tarkun
Ilhan
I
Canturk
Nuh Zafer
NZ
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D003928:Diabetic Nephropathies / Q000097:blood; D003929:Diabetic Neuropathies / Q000097:blood; D003930:Diabetic Retinopathy / Q000097:blood; D005215:Fasting / Q000097:blood; D005260:Female; D005293:Ferritins / Q000097:blood*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000209:etiology; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D002097:C-Reactive Protein; D002784:Cholesterol; D005293:Ferritins; D006442:Glycated Hemoglobin; D014280:Triglycerides