[Some specific features of drug resistance of Mycobacteria tuberculosis in patients with acutely progressive destructive forms of pulmonary tuberculosis].
A clear correlation has been found between the drug resistance of Mycobacterium tuberculosis (MBT) and the degree of immunodeficiency in 127 patients with acute destructive tuberculosis. The findings indicate that it is possible to use significant immunodeficiency as an early marker of the multidrug resistance of MBT and as a predictor of cheesy pneumonia. The fact that there was X-ray involution in one lung and concomitantly progression in the other suggests the presence of MBT strains showing different drug resistance. The efficiency of treatment for acute tuberculosis has been ascertained to be determined by MBT drug resistance.
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Chelnokova
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D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects / Q000276:immunology; D016867:Immunocompromised Host; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000276:immunology*