title: Cavernous hemangioma of the breast: mammographic and sonographic findings and follow-up in a patient receiving hormone-replacement therapy.
abstract: We report the case of a 78-year-old woman who had been receiving hormone-replacement therapy (HRT) for 6 years and had a 4-month history of a painless nodule in the 9 o'clock position in her right breast. Mammography performed 4 years previously had shown a 4-mm bilobed, ovoid, well-defined nodule in that location; mammography performed 1 year previously had shown that the nodule had increased to 6 mm. We performed mammographic and sonographic examinations, which revealed a 10-mm ovoid nodule in the same 9 o'clock position in the right breast. The imaging findings appeared to indicate benignity, but because of the increasing size of the nodule, we undertook an ultrasound-guided large-core needle biopsy. The histopathologic diagnosis was typical cavernous hemangioma. It was not excised, but HRT was discontinued. Follow-up mammography and sonography 8 months later showed that the nodule had decreased to 6 mm. We believe that the HRT played a contributory role in the increasing size of this patient's cavernous hemangioma. The use of ultrasound-guided large-core needle biopsy is reliable enough to ascertain the benignity of such masses and can thus avoid, if it is clinically appropriate, the need for their surgical removal.
authors.affiliation: Department of Radiology, Cedar Breast Center, McGill University, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, H3A 1A1, Canada.
authors.forename: Benoît
authors.initials: B
authors.lastname: Mesurolle
authors.forename: Marvin
authors.initials: M
authors.lastname: Wexler
authors.forename: Fawaz
authors.initials: F
authors.lastname: Halwani
authors.forename: Ann
authors.initials: A
authors.lastname: Aldis
authors.forename: Anna
authors.initials: A
authors.lastname: Veksler
authors.forename: Ellen
authors.initials: E
authors.lastname: Kao
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D005260:Female; D006392:Hemangioma, Cavernous / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008327:Mammography; D016217:Ultrasonography, Mammary