title: Pathophysiological aspects of diverticular disease of colon and role of large bowel motility.
abstract: Colonic diverticular disease (diverticulosis) is one of the most common gastrointestinal disorders in Western countries. This disorder is strictly related to aging and fibre intake, and still bears a discrete amount of morbidity. Numerous etiological co-factors have to date been implicated in the pathogenesis of the disease, yet the supporting evidence is still far from absolute. The present review considers the pathophysiology of colonic diverticular disease, with a special emphasis on factors related to abnormal colonic motility.
authors.affiliation: Clinica di Gastroenterologia ed Epatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Italy. gabassot@tin.it
authors.forename: Gabrio
authors.initials: G
authors.lastname: Bassotti
authors.forename: Fabio
authors.initials: F
authors.lastname: Chistolini
authors.forename: Antonio
authors.initials: A
authors.lastname: Morelli
mesh_terms: D003106:Colon / Q000503:physiopathology*; D043963:Diverticulosis, Colonic / Q000503:physiopathology*; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans