title: Alpha-cycloPNA: 1-aminocylopentane-1-carboxylic acid-derived peptide nucleic acid.
abstract: All four diastereoisomers of 3-thymine-1-((t)butoxycarbonyl)aminocyclopentane-1-carboxylic acid have been synthesised from (S)-dimethyl malate and thymine monomer 12 has been incorporated into an alpha-cycloPNA oligomer.
authors.affiliation: Chemistry, School of Engineering and Physical Sciences, Heriot-Watt University, Riccarton, Edinburgh, UK. n.m.howarth@hw.ac.uk
authors.forename: Nicola M
authors.initials: NM
authors.lastname: Howarth
authors.forename: Laurence P G
authors.initials: LP
authors.lastname: Wakelin
authors.forename: David M
authors.initials: DM
authors.lastname: Walker
mesh_terms: D003515:Cycloleucine / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007202:Indicators and Reagents; D020135:Peptide Nucleic Acids; D003515:Cycloleucine