title: Phosphorodiamides as prodrugs for antiviral nucleosides.
abstract: New phosphorodiamides of modified nucleoside monophosphates were synthesized and their antiviral properties were evaluated.
authors.affiliation: Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. aal@imb.ac.ru
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Shipitsyn
authors.forename: Natalya F
authors.initials: NF
authors.lastname: Zakirova
authors.forename: Evgeny F
authors.initials: EF
authors.lastname: Belanov
authors.forename: Tatyana R
authors.initials: TR
authors.lastname: Pronyaeva
authors.forename: Nina V
authors.initials: NV
authors.lastname: Fedyuk
authors.forename: Marina K
authors.initials: MK
authors.lastname: Kukhanova
authors.forename: Andrey G
authors.initials: AG
authors.lastname: Pokrovsky
mesh_terms: D019380:Anti-HIV Agents / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D015497:HIV-1 / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects; D009711:Nucleotides / Q000737:chemistry / Q000494:pharmacology*; D017553:Phosphorus Compounds / Q000737:chemistry / Q000494:pharmacology*; D010766:Phosphorylation; D011355:Prodrugs / Q000737:chemistry / Q000494:pharmacology*; D018119:Stavudine / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D015215:Zidovudine / Q000737:chemistry / Q000494:pharmacology
chemical_list: D019380:Anti-HIV Agents; D000998:Antiviral Agents; D009711:Nucleotides; D017553:Phosphorus Compounds; D011355:Prodrugs; D015215:Zidovudine; D018119:Stavudine; C436301:phosphorodiamidic acid