Analysing gene expressions with GRANK.
Unravelling overlapping clusters of functionally linked genes is a major challenge to current clustering programs. Algorithm GRANK permits systematic study of overlap between clusters of genes of a similar expression profile and large variation across a series of microarrays.


BACKGROUND
GRANK is freely available from http://www.bio.vu.nl/microb/research/tumor.html provided one adheres to the end-user license agreement in the associated manual.


BACKGROUND
Above website also supplies the in- and output files used in the example run.
de Boer
W P H
WP
Department of Medical Oncology, VU Medical Center, PO Box 7057, 1081 Hv Amsterdam, The Netherlands. wph.deboer@vumc.nl
Oudejans
J J
JJ
Meijer
C J L M
CJ
Lankelma
J
J
D000465:Algorithms; D016000:Cluster Analysis; D003628:Database Management Systems; D030562:Databases, Protein; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D016393:Lymphoma, B-Cell / Q000235:genetics / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011506:Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
D011506:Proteins