title: [Experimental systemic enzyme therapy of gouty and primary glomerulonephritis].
abstract: The influence of a systemic enzymotherapy on the morphological, biochemical, and functional manifestations of the kidney damage during the experimental gouty and primary glomerulonephritis is described in comparison to the results obtained by traditional methods.
authors.affiliation: Department of Pharmacology, Donetsk State Medical University, Prospekt Il'icha 16, 34000 Donetsk, Ukraine.
authors.forename: I V
authors.initials: IV
authors.lastname: Mukhin
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Nikolenko
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use; D000818:Animals; D002908:Chronic Disease; D003520:Cyclophosphamide / Q000627:therapeutic use; D004338:Drug Combinations; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005921:Glomerulonephritis / Q000188:drug therapy* / Q000209:etiology; D005937:Glucaric Acid / Q000009:adverse effects / Q000627:therapeutic use*; D006073:Gout / Q000150:complications*; D006074:Gout Suppressants / Q000009:adverse effects / Q000627:therapeutic use*; D006867:Hydrolases / Q000009:adverse effects / Q000627:therapeutic use*; D006996:Hypocalcemia / Q000139:chemically induced / Q000517:prevention & control; D007008:Hypokalemia / Q000139:chemically induced / Q000517:prevention & control; D008297:Male; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D051381:Rats; D012431:Rutin / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D006074:Gout Suppressants; D012431:Rutin; D000493:Allopurinol; C023295:Wobenzym; D003520:Cyclophosphamide; D011239:Prednisolone; D006867:Hydrolases; D005937:Glucaric Acid