Imiquimod is highly effective for extensive, hyperproliferative condyloma in children.
We describe a dramatic response to imiquimod of long-lasting, highly proliferative extensive perianal condylomas involving the anal canal in a 19-month-old girl. Her mother was free of condyloma and allegedly had no human papillomavirus (HPV) infection during pregnancy. There was no evidence of sexual abuse. Application of 5% imiquimod cream to the child every other day for 3 weeks resulted in almost complete resolution of the warts, with total clearance within another 2 weeks. The inflammatory reaction was moderate. Since there is still discussion of whether imiquimod may be prescribed for small children, this case of very extensive condyloma provides evidence that the compound is safe and highly effective.
Majewski
Slawomir
S
Department of Dermatology and Venereology, Warsaw School of Medicine, Warsaw, Poland.
Pniewski
Tomasz
T
Malejczyk
Magdalena
M
Jablonska
Stefania
S
D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000077271:Imiquimod; D007223:Infant
D000634:Aminoquinolines; D000077271:Imiquimod