Properties of triple helices formed by oligonucleotides containing 8-aminopurines.
The synthesis of parallel hairpins carrying 8-aminopurines is described. These hairpins have a high affinity for specific polypyrimidine sequences resulting in the formation of very stable triplexes.
Aviñó
A
A
Instituto de Biologia Molecular de Barcelona, Barcelona, Spain.
Frieden
M
M
Morales
J C
JC
de la Torre
B G
BG
Güimil-García
R
R
Orozco
M
M
González
C
C
Eritja
R
R
D001483:Base Sequence; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*; D013816:Thermodynamics
D009838:Oligodeoxyribonucleotides; D011687:Purines