title: Plasma lipid and lipoprotein concentrations in pregnancy induced hypertension.
abstract: OBJECTIVE
  Aim of this study was to evaluate implication of pregnancy induced hypertension on maternal plasma lipid, lipoprotein, apolipoprotein concentrations and lipid peroxidation products by a comparison of normal pregnancy vs. preeclampsia.
  
  
  METHODS
  Thirty-four women with preeclampsia and 32 healthy pregnant women (controls) in the third trimester were recruited for this study.
  
  
  RESULTS
  In the preeclamptic group plasma total triglyceride, low density lipoprotein cholesterol (LDL-C), malondialdehyde (MDA) and apolipoprotein B (apo-B) were significantly increased, while plasma high density lipoprotein cholesterol (HDL-C) was significantly decreased compared to that of control group. There was no significant difference in total cholesterol and apolipoprotein A1 (apo-A1) concentrations.
  
  
  CONCLUSIONS
  Our findings suggest that preeclampsia share some metabolic characteristics with coronary artery disease such as dislipidemia and increased lipid peroxidation. However lipoprotein concentrations may be better biochemical markers of dislipidemia in the preeclamptic state than the corresponding apolipoproteins.
authors.affiliation: Kocaeli University, Medical Faculty, Department of Biochemistry, Kocaeli, Turkey. mustafacekmen@hotmail.com
authors.forename: Mustafa Baki
authors.initials: MB
authors.lastname: Cekmen
authors.forename: Ayse Binnur
authors.initials: AB
authors.lastname: Erbagci
authors.forename: Ayse
authors.initials: A
authors.lastname: Balat
authors.forename: Can
authors.initials: C
authors.lastname: Duman
authors.forename: Hale
authors.initials: H
authors.lastname: Maral
authors.forename: Kivanc
authors.initials: K
authors.lastname: Ergen
authors.forename: Meltem
authors.initials: M
authors.lastname: Ozden
authors.forename: Ozcan
authors.initials: O
authors.lastname: Balat
authors.forename: Sevinc
authors.initials: S
authors.lastname: Kuskay
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy
chemical_list: D008055:Lipids; D008074:Lipoproteins; D008315:Malondialdehyde