title: Developmental biology. Rocks that roll zebrafish.
abstract: The vestibular organs of the inner ear of higher vertebrates control balance, and their counterparts in fish control both balance and hearing. Essential to the operation of these sensory organs are the biomineralized structures--otoconia in higher vertebrates or otoliths in fish--that deflect the sensory hair bundles situated beneath them. In her Perspective, Fekete explores the fascinating world of otolith biomineralization in zebrafish; revealing the importance of a protein called Starmaker for coordinating the shape and type of crystal in fish otoliths ( Söllner et al.).
authors.affiliation: Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA. dfekete@purdue.edu
authors.forename: Donna M
authors.initials: DM
authors.lastname: Fekete
mesh_terms: D000818:Animals; D002113:Calcification, Physiologic; D002119:Calcium Carbonate / Q000737:chemistry; D003460:Crystallization; D009024:Morphogenesis; D010037:Otolithic Membrane / Q000737:chemistry / Q000254:growth & development / Q000502:physiology* / Q000648:ultrastructure; D004856:Postural Balance; D011498:Protein Precursors / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D013550:Swimming; D015027:Zebrafish / Q000033:anatomy & histology / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D029961:Zebrafish Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*
chemical_list: D011498:Protein Precursors; D029961:Zebrafish Proteins; C478248:stm protein, zebrafish; D002119:Calcium Carbonate