[Effect of saponin from Tribulus terrestris on hyperlipidemia].
The preventive and therapeutic effects of saponin from Tribulus terrestris L. on diet-induced hyperlipidemia in mice have been studied. It showed that in preventive experiment the saponin could significantly low the levels of serum TC (P < 0.05), LDL-c (P < 0.01) and liver TC (P < 0.05), TG (P < 0.05), and increase the activities of superoxide-dismutase (SOD) in liver. The therapeutic experiment showed that the saponin could significantly reduce the contents of serum TC (P < 0.05) and liver TC (P < 0.01).
Chu
Shudi
S
School of Life Science, East China Normal University, Shanghai 200062.
Qu
Weijing
W
Pang
Xiufeng
X
Sun
Bin
B
Huang
Xiaoqing
X
D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D008078:Cholesterol, LDL / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D006949:Hyperlipidemias / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control; D000960:Hypolipidemic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000302:isolation & purification / Q000627:therapeutic use*; D013482:Superoxide Dismutase / Q000378:metabolism; D032444:Tribulus / Q000737:chemistry*; D014280:Triglycerides / Q000378:metabolism
D008078:Cholesterol, LDL; D004365:Drugs, Chinese Herbal; D000960:Hypolipidemic Agents; D012503:Saponins; D014280:Triglycerides; D002784:Cholesterol; D013482:Superoxide Dismutase