title: [A gastroenterology unit experience with adjuvant chemotherapy for non-metastatic colon cancer: results from 24 cases].
abstract: A prospective study was carried from January 1996 to December 2000 including patients that received adjuvant chemotherapy type FUFOL for colon carcinoma after curative surgery. Chemotherapy was recommended for all stage Dukes B2 end C. Adjuvant chemotherapy was administered to 24 patients (13 men and 11 women, mean age 56.7 +/- 11.5 years) with surgically resected stage B 2 in 7 cases (29%), C in 17 cases (71%). Treatment was completed in 15 patients (62%). With a median follow-up of 31.6 months, 11 patients had no recurrence, one patient had locoregional recurrence and 2 patients developed liver metastasis. Adjuvant FUFOL chemotherapy is actually the recommended adjuvant post-surgical treatment for colon cancer. This valided protocol is easily realised with a low toxicity and it can be done in gastro-enterology unit.
authors.affiliation: Service de Gastro-entérologie, Hôpital Habib Thameur, Tunis.
authors.forename: Najet
authors.initials: N
authors.lastname: Belhadj
authors.forename: Dalila
authors.initials: D
authors.lastname: Gargouri
authors.forename: Jamel
authors.initials: J
authors.lastname: Kharrat
authors.forename: Fethia
authors.initials: F
authors.lastname: Ben Hriz
authors.forename: Asma
authors.initials: A
authors.lastname: Kochlef
authors.forename: Afef
authors.initials: A
authors.lastname: Kilani
authors.forename: Malika
authors.initials: M
authors.lastname: Romani
authors.forename: Abdeljabbar
authors.initials: A
authors.lastname: Ghorbel
authors.forename: Raouf
authors.initials: R
authors.lastname: Cherif
authors.forename: Slim
authors.initials: S
authors.lastname: Khlifi
authors.forename: Anis
authors.initials: A
authors.lastname: Ben Maamer
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Letaief
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006757:Hospital Units; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D002955:Leucovorin; D005472:Fluorouracil