title: Factors determining long-term maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation.
abstract: BACKGROUND
  Long-term maintenance of sinus rhythm (SR) after successful cardioversion (CV) of persistent atrial fibrillation (AF) carries a low risk of stroke and may avoid the risks associated with anticoagulation.
  
  
  OBJECTIVE
  To determine the clinical and echocardiographic predictors of maintaining SR during one-year follow-up.
  
  
  METHODS
  The initial study group consisted of 205 patients with persistent AF of whom 104 (33 females, 71 males, mean age 60.4+/-7.4 years) were randomised to SR restoration and maintenance. The results of transthoracic echocardiography, obtained before CV, were compared between patients who remained in SR and those in whom AF recurred during a one-year follow-up period, using the linear and logistic regression analysis.
  
  
  RESULTS
  SR was present in 63.5% of patients at the end of the follow-up period. Of several analysed echocardiographic parameters, an increased left atrial area (<28 cm(2)) (p<0.02; RR 1.72, OR 1.09-2.71) and an increase in the fractional shortening of the left ventricle (range 25-40%, p<0.05, RR 1.2, OR 1.01-1.44) were significantly associated with SR maintenance during a 12-month follow-up period.
  
  
  CONCLUSIONS
  Left atrial area and left ventricular fractional shortening are the independent predictors of the maintenance of SR after successful CV in patients with persistent AF.
authors.affiliation: Chair and Department of Cardiology, Medical University of Warsaw, Poland.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Kosior
authors.forename: Marian
authors.initials: M
authors.lastname: Szulc
authors.forename: Radosław
authors.initials: R
authors.lastname: Piatkowski
authors.forename: Daniel
authors.initials: D
authors.lastname: Rabczenko
authors.forename: Adam
authors.initials: A
authors.lastname: Torbicki
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Opolski
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy*; D016279:Atrial Function, Left; D004452:Echocardiography; D004554:Electric Countershock; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011044:Poland; D012008:Recurrence; D016896:Treatment Outcome; D016277:Ventricular Function, Left