Application of the Rosenmund reaction to the synthesis of saturated fatty aldehydes.
A method is described for the simple and rapid formation of saturated fatty aldehydes from the corresponding acid chlorides. It is not suitable for the preparation of unsaturated aldehydes because of the partial reduction and positional and geometrical isomerization of the double bond in the chain.
White
H B
HB
Department of Biochemistry, University of Mississippi School of Medicine, Jackson, Mississippi 39216, USA.
Sulya
L L
LL
Cain
C E
CE
D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D004355:Drug Stability; D005227:Fatty Acids / Q000138:chemical synthesis* / Q000737:chemistry; D008722:Methods
D000447:Aldehydes; D005227:Fatty Acids; C001634:fatty aldehyde; C001647:hexadecanal