title: Gastrointestinal motility disorders and gastrointestinal prokinetic therapy.
abstract: Gastrointestinal motility disorders represent a diagnostic and therapeutic challenge. Disorders of gastrointestinal motility may result in accelerated transit, delayed transit, impaired relaxation, or inappropriate relaxation. The delayed transit disorders are the most important motility disorders of companion animals and may involve the esophagus (hypomotility and megaesophagus), stomach (delayed gastric emptying), small intestine (postoperative ileus and intestinal pseudo-obstruction), or colon (constipation and megacolon).
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010, USA. washabau@vet.upenn.edu
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Washabau
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000494:pharmacology / Q000627:therapeutic use; D020117:Cisapride / Q000494:pharmacology / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D004285:Dogs; D005765:Gastrointestinal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D007211:Indoles / Q000494:pharmacology / Q000627:therapeutic use; D007410:Intestinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D009037:Motilin / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D001572:Benzofurans; D005765:Gastrointestinal Agents; D007211:Indoles; C406662:prucalopride; C105050:tegaserod; D009037:Motilin; D020117:Cisapride