title: Chloroplast-to-nucleus signalling: a role for Mg-protoporphyrin.
abstract: Signalling from chloroplasts to the nucleus is an important feature of the coordination of nuclear and chloroplast gene expression required for the assembly of functional chloroplasts. Recent studies have indicated that accumulation of Mg-protoporphyrin, the first committed precursor of chlorophyll, is both necessary and sufficient for the regulation of nuclear genes by chloroplasts.
authors.affiliation: Department of Plant Sciences, University of Cambridge, Downing Street, CB2 3EA, Cambridge, UK. jcg2@mole.bio.cam.ac.uk
authors.forename: John C
authors.initials: JC
authors.lastname: Gray
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D002736:Chloroplasts / Q000378:metabolism*; D006540:Herbicides / Q000494:pharmacology; D008274:Magnesium / Q000378:metabolism*; D011524:Protoporphyrins / Q000378:metabolism*; D011724:Pyridazines / Q000494:pharmacology; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D006540:Herbicides; D011524:Protoporphyrins; D011724:Pyridazines; D008274:Magnesium; C008677:norflurazone