The epidemiologic incidence of congenital gastroschisis in Western Australia.
OBJECTIVE
The purpose of this study was to review the population incidence of congenital gastroschisis in Western Australia over the past 2 decades.


METHODS
A population-based incidence study of congenital gastroschisis from 1980 to 2001. Maternal and perinatal outcome data were collected to ascertain incidence, treatment, and outcome trends.


RESULTS
One hundred twenty-two cases of gastroschisis were identified. The median maternal age was 23 years (range, 16-35 years). Women aged <20 years were at a 7.82 increased risk (95% CI, 4.34-14.08); women aged 20 to 24 years were at a 3.24 increased risk (95% CI, 1.88-5.61) for fetal gastroschisis compared with women aged >or=25 years. An incidence analysis over time indicated a significant increase of gastroschisis cases from 1 of 10,000 births during the period 1980-1990 to the current rate of 2.4 of 10,000 births (P<.001). The perinatal mortality rate was 12.7% (95% CI, 8.7-16.7) with a 9.8% stillbirth rate (95% CI, 6.3-13.3).


CONCLUSIONS
There has been a sustained increase in the birth incidence of gastroschisis over the past decade, particularly in teenage women. A significant fetal death rate in the third trimester is observed.
Reid
Karen P
KP
Women and Infants Research Foundation, Perth, Australia.
Dickinson
Jan E
JE
Doherty
Dorota A
DA
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000653:Amniotic Fluid; D001724:Birth Weight; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D005317:Fetal Growth Retardation / Q000453:epidemiology; D020139:Gastroschisis / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay; D008423:Maternal Age; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D010289:Parenteral Nutrition, Total; D011247:Pregnancy; D011253:Pregnancy in Adolescence; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D012307:Risk Factors; D016216:Ultrasonography, Prenatal; D014904:Western Australia / Q000453:epidemiology; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins