title: [Results of a multidisciplinary and intensified treatment program for type 1 Diabetes Mellitus in a Chilean Public Hospital].
abstract: BACKGROUND
  During the last decade, the importance of glycemic control in the prevention of the microvascular complications of type 1 Diabetes Mellitus (DM1) was clearly demonstrated.
  
  
  OBJECTIVE
  To evaluate the metabolic and anthropometric results of a multidisciplinary intensified treatment program of DMI in children and adolescents.
  
  
  METHODS
  Report of 54 patients treated during 2001. The intensified treatment consisted of: multiple daily doses of insulin, frequent glycemic control, nutritional, psychological and educational support, and permanent availability of a diabetes nurse for telephonic support.
  
  
  RESULTS
  Thirty one patients were female, their mean age was 10.4 +/- 0.5 years old and 52% were experiencing puberty. Fifty three percent of the patients used 3 insulin doses per day, 95% changed rapid insulin dose based on glucose levels and 18% considered carbohydrates in their rapid insulin dosing. Mean glycosilated hemoglobin was 8.18 +/- 0.23% without differences by sex or pubertal status. Sex, pubertal stage and the number of insulin doses did not contribute to glycosilated hemoglobin changes. There were no differences in weight or BMI, but there was a decrease in height Z score from the admission to the program until the last control (0.1 +/- 0.1 vs--0.3 +/- 0.1 DS; p < 0.01).
  
  
  CONCLUSIONS
  A modified intensified modality of DM1 therapy for pediatric patients in a public hospital in Chile is feasible, achieving similar metabolic control, compared to international large centers.
authors.affiliation: Instituto de Investigaciones, Materno Infantil (IDIMI), Facultad de Medicina, Universidad de Chile, Hospital Clínico San Borja Arriarán, Servicio de Salud Santiago Centro, Santiago, Chile. ecodner@machi.med.uchile.cl
authors.forename: Ethel
authors.initials: E
authors.lastname: Codner
authors.forename: Verónica
authors.initials: V
authors.lastname: Mericq
authors.forename: Hernán
authors.initials: H
authors.lastname: García
authors.forename: Claudia
authors.initials: C
authors.lastname: López
authors.forename: Jeannette
authors.initials: J
authors.lastname: Cáceres
authors.forename: Ximena
authors.initials: X
authors.lastname: Gaete
authors.forename: Alejandra
authors.initials: A
authors.lastname: Avila
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D002677:Chile; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism / Q000628:therapy*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D008297:Male; D018709:Statistics, Nonparametric; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin