[Spontaneous blood blister formation swellings of the oral mucosa].
An 88 year-old man was hospitalized because of bullous pemphigoid of the skin with detectable autoantibodies against type XVII collagen. During his stay in the hospital, he developed easily bleeding hemorrhagic bullous lesions of the oral mucosa, which were thought to be an oral manifestation of bullous pemphigoid. A thorough blood examination showed acquired haemophilia A, related to the development of autoantibodies against factor VIII.
Vissink
A
A
Uit de afdeling Mondziekten, Kaakchirurgie en Bijzondere Tandheelkunde en de afdeling Dermatologie van het Academisch Ziekenhuis Groningen. a.vissink@kchir.azg.nl
van Coevorden
A M
AM
Spijkervet
F K
FK
Jonkman
M F
MF
D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000032:analysis; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000276:immunology; D006467:Hemophilia A / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology*; D010391:Pemphigoid, Bullous / Q000175:diagnosis / Q000276:immunology / Q000473:pathology
D001323:Autoantibodies; D005169:Factor VIII