title: Cadmium accumulation and elimination in tissues of juvenile olive flounder, Paralichthys olivaceus after sub-chronic cadmium exposure.
abstract: Experiments were carried out to investigate the accumulation and elimination of cadmium (Cd) in tissues (gill, intestine, kidney, liver and muscle) of juvenile olive flounder, Paralichthys olivaceus, exposed to sub-chronic concentrations (0, 10, 50, 100 microg l(-1)) of Cd. Cd exposure resulted in an increased Cd accumulation in tissues of flounder with exposure periods and concentration, and Cd accumulation in gill and liver increased linearly with the exposure time. At 20 days of Cd exposure, the order of Cd accumulation in organs was gill > intestine > liver > kidney > muscle and after 30 days of exposure, those were intestine > gill > liver > kidney > muscle. An inverse relationship was observed between the accumulation factor (AF) and the exposure level, but AF showed an increase with exposure time. During the depuration periods, Cd concentration in the gill, intestine and liver decreased immediately following the end of the exposure periods. No significant difference was found Cd in concentration in the kidney and muscle during depuration periods. The order of Cd elimination rate in organs were decreased intestine > liver > gill during depuration periods.
authors.affiliation: Department of Aquatic Life Medicine, Pukyong National University, 599-1 Daeyon-dong, Namga, 608-737, Pusan, South Korea.
authors.forename: Seong Gil
authors.initials: SG
authors.lastname: Kim
authors.forename: Jung Hoon
authors.initials: JH
authors.lastname: Jee
authors.forename: Ju Chan
authors.initials: JC
authors.lastname: Kang
mesh_terms: D000818:Animals; D002104:Cadmium / Q000032:analysis / Q000378:metabolism*; D004781:Environmental Exposure; D005432:Flounder / Q000254:growth & development / Q000378:metabolism*; D005880:Gills / Q000737:chemistry / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000737:chemistry; D007668:Kidney / Q000737:chemistry / Q000378:metabolism; D007723:Korea; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D009132:Muscles / Q000737:chemistry / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000378:metabolism*
chemical_list: D014874:Water Pollutants, Chemical; D002104:Cadmium