title: Volume effect on sensitivity of nucleic acid amplification tests for detection of Chlamydia trachomatis in urine specimens from females.
abstract: Nucleic acid amplification tests (NAATs) for the detection of Chlamydia trachomatis are routinely used on first-catch urine (FCU) specimens. We analyzed data from a head-to-head comparison of NAATs on female FCU specimens and found that the volume of urine collected could affect test performance.
authors.affiliation: Department of Laboratory Medicine, University of California, San Francisco, California 94110, USA. jevemo@itsa.ucsf.edu
authors.forename: Jeanne
authors.initials: J
authors.lastname: Moncada
authors.forename: Joan M
authors.initials: JM
authors.lastname: Chow
authors.forename: Julius
authors.initials: J
authors.lastname: Schachter
mesh_terms: D002690:Chlamydia Infections / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D021141:Nucleic Acid Amplification Techniques; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods*; D014556:Urine / Q000382:microbiology*