Hodgkin and non-Hodgkin lymphoma involving bone marrow.
The role of bone marrow examination in diagnosis and staging of patients with Hodgkin lymphoma, B-non-Hodgkin lymphoma, and T-non-Hodgkin lymphoma is reviewed. Optimal routine and specialized bone marrow examination techniques are discussed. The salient morphologic, immunophenotypic, and genetic features of mature and immature B, T neoplasms and classic Hodgkin lymphoma in bone marrow are delineated, along with recommendations to distinguish these overt neoplasms from non-neoplastic processes.
Viswanatha
David
D
Department of Pathology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Foucar
Kathryn
K
D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology*; D002869:Chromosome Aberrations; D006689:Hodgkin Disease / Q000145:classification / Q000209:etiology / Q000473:pathology*; D006801:Humans; D016130:Immunophenotyping; D017404:In Situ Hybridization, Fluorescence; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000209:etiology / Q000473:pathology*; D009367:Neoplasm Staging