Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.
Stretches of parallel-stranded (ps) double-helical DNA can arise within antiparallel-stranded (aps) Watson-Crick DNA in looped structures or in the presence of sequence mismatches. Here we studied an effect of a pyrimidinone-G (PG) base pair on the stability and conformation of the ps DNA to explore whether P is useful as a structural probe.
Kaluzhny
D N
DN
Engelhardt Institute of Molecular Biology RASc, Moscow, Russia.
Mikhailov
S N
SN
Efimtseva
E V
EV
Borisova
O F
OF
Florentiev
V L
VL
Shchyolkina
A K
AK
Jovin
T M
TM
D020137:Base Pair Mismatch; D020029:Base Pairing; D001483:Base Sequence; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry; D003853:Deoxyribonucleosides / Q000737:chemistry*; D005456:Fluorescent Dyes; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D011744:Pyrimidinones; D013816:Thermodynamics
D003853:Deoxyribonucleosides; D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D011744:Pyrimidinones; D004247:DNA