title: Ethmocephaly caused by de novo translocation 18;21--prenatal diagnosis.
abstract: Ethmocephaly is a rare anomaly associated with partial failure of cleavage of the prosencephalon. Morphologically, it is closely related to cyclopia. We present an extremely rare case of ethmocephaly diagnosed in utero and caused by an unbalanced de novo translocation 18;21.
authors.affiliation: Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel. itskovitz@rambam.health.gov.il
authors.forename: Israel
authors.initials: I
authors.lastname: Goldstein
authors.forename: Amir
authors.initials: A
authors.lastname: Weissman
authors.forename: Ronit
authors.initials: R
authors.lastname: Brill-Zamir
authors.forename: Ilana
authors.initials: I
authors.lastname: Laevsky
authors.forename: Arie
authors.initials: A
authors.lastname: Drugan
mesh_terms: D002887:Chromosomes, Human, Pair 18; D002891:Chromosomes, Human, Pair 21; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000235:genetics; D016142:Holoprosencephaly / Q000000981:diagnostic imaging* / Q000196:embryology / Q000235:genetics; D006801:Humans; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D014178:Translocation, Genetic; D016216:Ultrasonography, Prenatal