[Strategies for fertility preservation after anti-cancer therapy].
A tremendous advance in the field of cancer therapy resulted in a substantial improvement of long-term survival of oncological patients. The most frequent side effect of either chemotherapy or radiotherapy is a partial or complete lost of fertility potential. This paper reviews current knowledge on the fertility preservation strategies for patients facing oncological problems and the risks of iatrogenic infertility. The cryopreservation of spermatozoa or testicular tissue combined with assisted reproductive technology is the optimal solution for male patients. In the case of female patients, the use of ovarian transposition, ovarian suppression and ovarian tissue cryopreservation seem to be the valuable options for fertility prevention. The cryopreservation of embryos is another possible solution, although this procedure is only limited to the couples. On the other hand, there are still controversies regarding the ethical issues concerning gametes and embryos banking.
Putowski
Lechosław
L
II Katedry i Kliniki Ginekologii AM w Lublinie.
Kuczyński
Waldemar
W
D000970:Antineoplastic Agents / Q000009:adverse effects*; D015925:Cryopreservation / Q000941:ethics / Q000592:standards; D005260:Female; D005298:Fertility; D006801:Humans; D007246:Infertility / Q000209:etiology / Q000517:prevention & control*; D007247:Infertility, Female / Q000517:prevention & control; D007248:Infertility, Male / Q000517:prevention & control; D008297:Male; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D010053:Ovary; D011247:Pregnancy; D011878:Radiotherapy / Q000009:adverse effects*; D012662:Semen Preservation / Q000941:ethics / Q000592:standards; D020858:Tissue and Organ Harvesting / Q000941:ethics / Q000592:standards
D000970:Antineoplastic Agents