Commercial exploitation of transgenics.
A series of examples of the application of recombinant nucleic acid technology to the production of transgenic organisms is presented. The review considers the distinct advantages of producing certain recombinant biomolecules in appropriate eucaryotic systems rather than in the traditional procaryotic ones. Gene therapy in humans and the production of transgenic animals and plants are discussed. Concerns about the inadvertant construction of new pathogens and ethical considerations about interfering with poorly understood ecosystems are addressed.
Smith
T J
TJ
National Diagnostics Centre, BioResearch Ireland, University College, Galway, Republic of Ireland.