Maternal carriage and antimicrobial resistance profile of group B Streptococcus.
BACKGROUND
The aim of this study was to determine the prevalence of group B Streptococcus (GBS) colonization and to evaluate the antimicrobial resistance profile in women in the third trimester of pregnancy.


METHODS
A total of 310 pregnant women, referred in weeks 35 to 37 of gestation, were screened for GBS colonization during a 10-month period. Samples were collected from the vagina and the rectum.


RESULTS
The colonization rate was 10.6% and 22 women (66.7%) had both positive vaginal and rectal cultures. Rates of GBS colonization were significantly lower in patients aged 24 years or older and in those with a third or later pregnancy. None of the isolates were resistant to penicillin and ampicillin, whereas 21.2% and 9.1% showed resistance to erythromycin and clindamycin, respectively.


CONCLUSIONS
Screening and antimicrobial susceptibility testing of GBS during pregnancy are important to guide appropriate therapy.
Arisoy
A S
AS
Dept. of Infectious Diseases and Clinical Microbiology, Medical Faculty, Celal Bayar University, 45020 Manisa, Turkey.
Altinişik
B
B
Tünger
O
O
Kurutepe
S
S
Ispahi
C
C
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002353:Carrier State; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D015994:Incidence; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008403:Mass Screening; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D011336:Probability; D011446:Prospective Studies; D018570:Risk Assessment; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000302:isolation & purification; D014421:Turkey / Q000453:epidemiology
D000900:Anti-Bacterial Agents