Synthetic studies on guanofosfocin: glycosylation of 8-oxo-purine nucleosides via Mitsunobu reaction.
In model studies directed to the total synthesis of guanofosfocins, a unique glycosidic bond formation between the 8-oxo-purine nucleosides and mannopyranose derivatives under Mistunobu conditions is described.
Sugimura
Hideyuki
H
Faculty of Education and Human Science, Yokohama National University, Hodogaya-ku, Yokohama, Japan. sugimura@edhs.ynu.ac.jp
Koizumi
Akiyoshi
A
Kiyohara
Wataru
W
D006031:Glycosylation; D007202:Indicators and Reagents; D008358:Mannose / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D008958:Models, Molecular; D008968:Molecular Conformation; D011684:Purine Nucleosides / Q000737:chemistry*; D013302:Streptomyces; D014242:Trichoderma
D007202:Indicators and Reagents; D011684:Purine Nucleosides; C479167:guanofosfocin; D008358:Mannose