Advances in bioconversion of anthracycline antibiotics.
During the last decade new anthracycline-type structures with potential usefulness in cancer treatment have been supplied both by new microbial strains and by bioconversions of precursor molecules employing cells or enzymes. We highlight recent advances in bioconversion of anthracycline structures with the main focus on late transformations such as are carried out by oxidoreductases.
Gräfe
U
U
Central Institute of Microbiology and Experimental Therapy, GDR Academy of Sciences, P.O. Box 73, Jena 6900, G.D.R.
Dornberger
K
K
Wagner
C
C
Eckardt
K
K