title: Drug hypersensitivity syndrome to carbamazepine and human herpes virus 6 infection: case report and literature review.
abstract: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially fatal adverse drug reaction are highlighted.
authors.affiliation: Outpatient Dept. of Internal Medicine, University Hospital Basel, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Zeller
authors.forename: N
authors.initials: N
authors.lastname: Schaub
authors.forename: I
authors.initials: I
authors.lastname: Steffen
authors.forename: E
authors.initials: E
authors.lastname: Battegay
authors.forename: H H
authors.initials: HH
authors.lastname: Hirsch
authors.forename: A J
authors.initials: AJ
authors.lastname: Bircher
mesh_terms: D000328:Adult; D001483:Base Sequence; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D015654:Herpesvirus 6, Human / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D018570:Risk Assessment; D019349:Roseolovirus Infections / Q000150:complications / Q000175:diagnosis*; D012640:Seizures / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D002220:Carbamazepine