title: The growing teratoma syndrome.
abstract: Growing teratoma syndrome is defined as enlarging masses of mature teratoma following chemotherapy for malignant nonseminomatous germ-cell tumors. Typically, there is associated normalization of initially elevated serum tumor markers. We describe clinical and imaging findings in a case of growing teratoma syndrome originating from immature teratoma of the ovary in a 12-year-old girl. Familiarity with this unusual entity is important to avoid confusion with advancing malignancy.
authors.affiliation: Department of Radiology, The Floating Hospital for Children, Boston, MA, USA. knimkin@partners.org
authors.forename: Katherine
authors.initials: K
authors.lastname: Nimkin
authors.forename: Punita
authors.initials: P
authors.lastname: Gupta
authors.forename: Roy
authors.initials: R
authors.lastname: McCauley
authors.forename: Brian F
authors.initials: BF
authors.lastname: Gilchrist
authors.forename: Marc S
authors.initials: MS
authors.lastname: Lessin
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D013724:Teratoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents