Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine.
Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine were synthesized and their in vitro anti-HIV activity was determined.
Ermolinsky
Boris S
BS
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Efimtseva
Ekaterina V
EV
Alexeev
Cyrill S
CS
Mikhailov
Sergey N
SN
Balzarini
Jan
J
De Clercq
Erik
E
D000677:Amsacrine / Q000031:analogs & derivatives*; D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002460:Cell Line; D019281:Dimerization; D015226:Dinucleoside Phosphates / Q000138:chemical synthesis*; D006151:Guanosine / Q000031:analogs & derivatives*; D006678:HIV / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D014779:Virus Replication / Q000187:drug effects; D015215:Zidovudine
D019380:Anti-HIV Agents; D000998:Antiviral Agents; D015226:Dinucleoside Phosphates; D000677:Amsacrine; C050734:1-methylamsacrine; D006151:Guanosine; C020770:1-methylguanosine; D015215:Zidovudine