Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma.
In this study, we have shown that there are seasonal differences in the onset of the (Epstein-Barr virus) EBV-positive and -negative forms of paediatric Hodgkin's lymphoma (HL). This suggests aetiological differences between the two forms of this disease. EBV-positive HL might be a rare consequence of primary EBV infection.
Reiman
A
A
Department of Pathology, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Powell
J E
JE
Flavell
K J
KJ
Grundy
R G
RG
Mann
J R
JR
Parkes
S
S
Redfern
D
D
Young
L S
LS
Murray
P G
PG
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000453:epidemiology / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007231:Infant, Newborn; D015995:Prevalence; D012621:Seasons; D006113:United Kingdom / Q000453:epidemiology; D014763:Viral Matrix Proteins / Q000032:analysis
C037662:EBV-associated membrane antigen, Epstein-Barr virus; D014763:Viral Matrix Proteins