title: Neurobiology: double trouble for neurons.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Fortini
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism*; D053829:Amyloid Precursor Protein Secretases; D000818:Animals; D016282:Aspartic Acid Endopeptidases; D050882:CREB-Binding Protein; D015820:Cadherins / Q000378:metabolism*; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D009474:Neurons / Q000378:metabolism* / Q000473:pathology; D009687:Nuclear Proteins / Q000378:metabolism; D053764:Presenilin-1; D015534:Trans-Activators / Q000378:metabolism
chemical_list: D015820:Cadherins; D017362:Cyclic AMP Response Element-Binding Protein; D008565:Membrane Proteins; D009687:Nuclear Proteins; C508853:PSEN1 protein, human; D053764:Presenilin-1; D015534:Trans-Activators; D050882:CREB-Binding Protein; C494363:CREBBP protein, human; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human