[Prevalence of cardiovascular risk factors in a cohort of affected by the toxic oil syndrome].
OBJECTIVE
During the first stages of the toxic oil syndrome (TOS), elevations of the blood pressure as well as increases in the cholesterol, glucose and triglycerides levels were reported. Here we analyze these cardiovascular risk factors in the chronic phase of the illness and their distribution according to the severity of the illness. We also compare them with those found in the general population.


METHODS
We studied a sample of 1,862 individuals aged between 35 and 65 years. A medical examination was performed in each and blood pressure, weight, height, tobacco consumption, cholesterol, glucose and triglycerides levels were measured.


RESULTS
The prevalence of high blood pressure (>140/90 mmHg) was 46.1% and the prevalence of diabetes mellitus (>126 mg/dl) was 9.1%. The prevalence of obesity (BMI>30) was 24.9%. 11.8% of patients had hypertriglyceridemia (>200 mg/dl) and 19.8% had hypercholesterolemia (>250 mg/dl). 37.9% were smokers. The standardized prevalence rate (SPR) of high blood pressure was 1.35 (95% CI, 1.28-1.44); tobacco consumption SPR=1.27 (95% CI, 1.20-1.36); hypercholesterolemia SPR=1.10 (95% CI, 1.01-1.21). The prevalence of risk factors was higher among the most seriously affected subjects.


CONCLUSIONS
The chronic phase of TOS is characterized by a high prevalence of cardiovascular risk factors, which was significantly higher than that expected in the general population.
Gómez de la Cámara
Agustín
A
Unidad de Investigación-Epidemiología Clínica, Hospital Universitario 12 de Octubre, Madrid, España. acamara@h12o.es
Gómez Mateos
M Angeles
MA
Ferrando Vivas
Paloma
P
Barianca Oyagüe
M Teresa
MT
Abiatua Borda
Ignacio
I
Posada de la Paz
Manuel
M
D000328:Adult; D000368:Aged; D029741:Brassica rapa; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology*; D005229:Fatty Acids, Monounsaturated; D005260:Female; D005506:Food Contamination; D006801:Humans; D008297:Male; D008875:Middle Aged; D010938:Plant Oils / Q000506:poisoning*; D015995:Prevalence; D000074262:Rapeseed Oil; D012307:Risk Factors; D013577:Syndrome
D005229:Fatty Acids, Monounsaturated; D010938:Plant Oils; D000074262:Rapeseed Oil