Ultrasound as a tool in experimental research of macro- and microcirculation.
Peculiarities of application of two modes of ultrasonic measurements of blood flow in experimental research are considered, which are based on Doppler effect and on differential transit-time of upstream and downstream sound propagation. The efficiency of high-frequency ultrasound flowmeter equipped with 26.8 MHz transducers was demonstrated in measurements of blood flow in rat midbrain and coronary arteries. This approach can be used for evaluation of the dynamics of cardiac output with an intravascular catheter 0.6 mm in diameter working at 33 MHz. The probe and electronic scheme of the devise for measuring blood flow in microvessels are described. Blood flow rate measured in mesentery and m. cremaster arterioles under normal conditions was 2-12 mm/sec. One-element probe working at 38.5 MHz provided stable recording of blood microflows in 30-40-micro vessels.
Matsievskii
D D
DD
Institute of General Pathology and Pathological Physiology, Russian Academy of Medical Sciences, Moscow.
D000818:Animals; D001158:Arteries / Q000473:pathology; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply / Q000378:metabolism; D003331:Coronary Vessels / Q000473:pathology; D004837:Epinephrine / Q000494:pharmacology; D008833:Microcirculation; D051381:Rats; D013997:Time Factors; D014465:Ultrasonics; D018608:Ultrasonography, Doppler / Q000379:methods*
D004837:Epinephrine