title: Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.
abstract: Stretches of parallel-stranded (ps) double-helical DNA can arise within antiparallel-stranded (aps) Watson-Crick DNA in looped structures or in the presence of sequence mismatches. Here we studied an effect of a pyrimidinone-G (PG) base pair on the stability and conformation of the ps DNA to explore whether P is useful as a structural probe.
authors.affiliation: Engelhardt Institute of Molecular Biology RASc, Moscow, Russia.
authors.forename: D N
authors.initials: DN
authors.lastname: Kaluzhny
authors.forename: S N
authors.initials: SN
authors.lastname: Mikhailov
authors.forename: E V
authors.initials: EV
authors.lastname: Efimtseva
authors.forename: O F
authors.initials: OF
authors.lastname: Borisova
authors.forename: V L
authors.initials: VL
authors.lastname: Florentiev
authors.forename: A K
authors.initials: AK
authors.lastname: Shchyolkina
authors.forename: T M
authors.initials: TM
authors.lastname: Jovin
mesh_terms: D020137:Base Pair Mismatch; D020029:Base Pairing; D001483:Base Sequence; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry; D003853:Deoxyribonucleosides / Q000737:chemistry*; D005456:Fluorescent Dyes; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D011744:Pyrimidinones; D013816:Thermodynamics
chemical_list: D003853:Deoxyribonucleosides; D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D011744:Pyrimidinones; D004247:DNA