Pituitary stalk metastasis from breast cancer treated with systemic chemotherapy.
We describe a 61-year-old woman with diabetes insipidus caused by a pituitary stalk metastasis from breast cancer. She had a medical history of breast conservation therapy for early breast cancer 5 years previously. Pituitary, lung, liver, bone and neck lymphnode metastases was revealed at the same time. She received systemic chemotherapy consisting of docetaxel and cisplatin. After chemotherapy MRI finding in pituitary gland was improved, lung and liver metastases also improved, however, symptoms of diabetes insipidus did not improve. She is alive, receiving endocrine treatment for 2 years, since onset of diabetes insipidus.
Murata
Yoriko
Y
Department of Tumor Radiology, Program of Tumor Biology and Regulation, Kochi Medical School, Nankoku 783-8505, Kochi, Japan. muratay@kochi-ms.ac.jp
Ogawa
Yasuhiro
Y
Yokoe
Isamu
I
Kariya
Shinji
S
Morio
Kazuo
K
Sasaki
Toshikazu
T
Nishioka
Akihito
A
Yoshida
Shoji
S
D000970:Antineoplastic Agents / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D001921:Brain / Q000473:pathology; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy*; D002945:Cisplatin / Q000627:therapeutic use; D003919:Diabetes Insipidus / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010911:Pituitary Neoplasms / Q000473:pathology / Q000556:secondary*; D043823:Taxoids / Q000627:therapeutic use
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin