title: [Osler's disease--a risk factor for stroke].
abstract: BACKGROUND
  Osler's disease is an inherited disease of blood vessels that causes haemorrhage from the nasal mucosa, gastrointestinal tract, lungs or the urinary tract. Patients may also have abnormal intracerebral vessels.
  
  
  METHODS
  A patient with Osler's disease and recurrent epistaxis suffered a cerebellar infarction. He had no other risk factors for stroke. An arteriovenous fistula was demonstrated in the right lung. This fistula was the probable source or aberrant pathway of an embolus to the cerebellum. The patient was treated with endovascular occlusion of the fistula to prevent further emboli to the brain.
  
  
  CONCLUSIONS
  Embolisation of thrombi from arteriovenous fistulae in the lungs is a rare cause of stroke, though important since secondary prophylaxis is very effective. Physicians should consider this possibility in the occasional patient with embolic stroke in whom no other risk factor is established.
authors.affiliation: Nevrologisk avdeling, Nordlandssykehuset, Bodø. morten.horn@ulleval.no
authors.forename: Morten Andreas
authors.initials: MA
authors.lastname: Horn
authors.forename: Kjell Arne
authors.initials: KA
authors.lastname: Hugaas
authors.forename: Rolf
authors.initials: R
authors.lastname: Salvesen
mesh_terms: D001164:Arteriovenous Fistula / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D002531:Cerebellum / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis / Q000209:etiology*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed