Effects on blood pressure decrease in response to PAF of Impatiens textori MIQ.
A 35% EtOH extract of flowers of Impatiens textori MIQ. showed an inhibitory effect on blood pressure decrease in response to platelet activating factor (PAF) measured with a blood pressure monitoring system. Bioassay-guided fractionation of the 35% EtOH extract (IT) led to isolation of the flavones apigenin (1) and luteolin (3), which significantly inhibited blood pressure decrease in response to PAF. Their compounds and apigenin 7-glucoside (2), chrysoeriol (4), quercetin (5), quercetin 3-glucoside (6), kaempferol (7), kaempferol 3-glucoside (8) and kaempferol 3-rhamnosyldiglucoside (9) were also isolated from the flowers of I. textori for the first time. This study revealed that the flowers of I. textori might be a possible anti-allergy agent.
Ueda
Yoshimi
Y
School of Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.
Oku
Hisae
H
Iinuma
Munekazu
M
Ishiguro
Kyoko
K
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D035264:Flowers; D029069:Impatiens; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010972:Platelet Activating Factor / Q000494:pharmacology*
D010936:Plant Extracts; D010972:Platelet Activating Factor