title: [MRI-guided surgery with high intensity focused ultrasound].
abstract: High-intensity focused ultrasound allows high-precision, non-invasive thermocoagulation of tissues within seconds, with sparing of surrounding areas. The resulting tissue necrosis is so sharply demarcated that the technique is also defined focused ultrasound surgery (FUS). The combination with magnetic resonance imaging (MRI) allows an exact definition of the target volume and a safe guidance of FUS. The present paper describes the physical equipment necessary to perform MRI-guided FUS, and reports an example of application of this technique for the therapy of breast cancer. Finally, the paper outlines further examples of FUS application and future perspectives.
authors.affiliation: Forschungsschwepunkt Innovative Krebsdiagnostik und -therapie, Deutsches Krebsforschungszentrum Heidelberg. j.jenne@dkfz.de
authors.forename: Jürgen W
authors.initials: JW
authors.lastname: Jenne
authors.forename: Ralf
authors.initials: R
authors.lastname: Rastert
authors.forename: Guido
authors.initials: G
authors.lastname: Rademaker
authors.forename: Gabriela
authors.initials: G
authors.lastname: Divkovic
authors.forename: Jürgen
authors.initials: J
authors.lastname: Debus
authors.forename: Peter E
authors.initials: PE
authors.lastname: Huber
mesh_terms: D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008954:Models, Biological; D016343:Monitoring, Intraoperative / Q000295:instrumentation / Q000379:methods*; D013514:Surgical Procedures, Operative / Q000379:methods; D014464:Ultrasonic Therapy / Q000379:methods*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA