Prognostic value of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography imaging for patients with prostate cancer.
OBJECTIVE
The purpose of this study was to investigate the prognostic value of measuring glucose metabolism of primary prostate cancer lesions, using 2-Deoxy-2-[F-18]Fluoro-D-Glucose positron emission tomography (FDG-PET).


METHODS
Forty-two patients with prostate cancer were investigated with FDG-PET, and standardized uptake value (SUV) of the prostate was calculated. After PET study, radical prostatectomy was performed in 17 patients (RPT group), and endocrine therapy in 25 patients (ET group). Relapse-free survival curves were created by the Kaplan-Meier method.


RESULTS
In the RPT group, the patients with high SUV had a poorer prognosis compared to those with low SUV (P = 0.033). In the ET group, the patients with high SUV were likely to have a poorer prognosis with low significance at a level of P = 0.087.


CONCLUSIONS
FDG-PET appeared to have a defined prognostic value for patients with prostate cancer undergoing radical prostatectomy, and more patients need to be studied for patients undergoing endocrine therapy.
Oyama
Nobuyuki
N
Department of Urology, Fukui Medical University, Fukui, Japan. Oyaman@mir.wustl.edu
Akino
Hironobu
H
Suzuki
Yuji
Y
Kanamaru
Hiroshi
H
Miwa
Yoshiji
Y
Tsuka
Harutoshi
H
Sadato
Norihiro
N
Yonekura
Yoshiharu
Y
Okada
Kenichiro
K