An adamantanone derivative that is an original modulator of redox processes in the cytochrome P-450 system can serve as an effective remedy against obliterating angiopathy of lower extremities.
Kovalev
I E
IE
Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 117977 Russia.
Koshkin
V M
VM
Shipulina
N V
NV
Rumyantseva
E I
EI
D000218:Adamantane / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D001809:Blood Viscosity / Q000187:drug effects; D002908:Chronic Disease; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D010084:Oxidation-Reduction / Q000187:drug effects; D013919:Thromboangiitis Obliterans / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D018608:Ultrasonography, Doppler
D003577:Cytochrome P-450 Enzyme System; D000218:Adamantane; C001862:adamantanone