title: Subthalamic nucleus tumor causing hyperphagia--case report.
abstract: A 42-year-old woman with locally advanced breast cancer developed headache just after completing adjuvant chemotherapy. Magnetic resonance imaging revealed a mass located in the left subthalamic nucleus (STN) and involving the posterior part of the thalamus and the hypothalamus. The patient refused a radiologically guided biopsy and gamma knife treatment was not financially possible. Palliative whole brain radiotherapy with hormonal therapy was administered. The patient gained 19 kg body weight during 4 months follow up because of hyperphagia. This solitary tumor, either a breast cancer metastasis or a primary tumor, involving the STN is extremely unusual.
authors.affiliation: Medical Oncology Department, Adnan Menderes University Hospital, Aydin, Turkey. sbarutca@yahoo.com
authors.forename: Sabri
authors.initials: S
authors.lastname: Barutca
authors.forename: Mehmet
authors.initials: M
authors.lastname: Turgut
authors.forename: Nezih
authors.initials: N
authors.lastname: Meydan
authors.forename: Yelda
authors.initials: Y
authors.lastname: Ozsunar
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D006963:Hyperphagia / Q000209:etiology* / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000628:therapy; D020531:Subthalamic Nucleus / Q000473:pathology*