Polycystic ovaries, precocious puberty and acquired hypothyroidism: The Van Wyk and Grumbach syndrome.
Long-standing acquired hypothyroidism can rarely be associated with precocious puberty and polycystic ovaries. The authors report such a case, which responded to the simple replacement of thyroid hormone. It is important to look for hypothyroidism in girls with ovarian masses and precocious puberty to avoid surgery on the ovaries.
Chattopadhyay
Anindya
A
Department of Pediatric Surgery, Kasturba Medical College, Manipal, Karnataka, India.
Kumar
Vijaya
V
Marulaiah
Mohan
M
D002648:Child; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000188:drug therapy; D011629:Puberty, Precocious / Q000150:complications* / Q000188:drug therapy; D013577:Syndrome; D013974:Thyroxine / Q000627:therapeutic use
D013974:Thyroxine