Histopathology of the liver in adolescents co-infected with HIV and hepatitis C virus.
Chronic hepatitis C is usually a mild disease in children; however, the evolution of children co-infected with HIV is unknown. We report the liver biopsy results of seven adolescents co-infected for over 13 years. According to the Metavir scoring system, liver specimens were classified A1-F1 in three patients and A2-F1 in four. Mild fibrosis progression is mainly explained by young age at hepatitis C virus contamination and the lack of severe immunodeficiency in the study population.
Thuret
Isabelle
I
Department of Pediatrics, Hôpital La Timone, Marseille, France.
Lacaille
Florence
F
Canioni
Danielle
D
Roquelaure
Bertrand
B
Michel
Gerard
G
Blanche
Stéphane
S
D000293:Adolescent; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006526:Hepatitis C / Q000150:complications / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000150:complications / Q000473:pathology; D008297:Male; D013997:Time Factors