Defecation mechanisms after proctocolectomy and ileal pouch--anal anastomosis in dogs.
OBJECTIVE
The role of intrinsic pouch motility after ileal pouch-anal anastomosis (IPAA) during defecation is still speculative.


METHODS
IPAA was performed in 12 dogs. Defecation mechanisms were evaluated by motility recordings during spontaneous defecation and during expulsion of an endoluminal balloon and by radiography with sequential sector-related gray scale analysis.


RESULTS
Spontaneous defecations appeared without significant changes in electrical or mechanical activity of the pouch. Sequential filling of the pouch led to defecation in only seven dogs while the others did not succeed in emptying their pouch even with maximal balloon inflation. Neither strain gauge measurements nor electromyography demonstrated peristaltic contractions of the pouch during defecation while sector-related gray scale analysis revealed strong contractions of the abdominal wall during pouch emptying.


CONCLUSIONS
Pouch emptying is independent of intrinsic pouch motility. The ileoanal pouch acts as a functionally passive reservoir, and its evacuation is initiated by a rise of the intra-abdominal pressure.
Willis
S
S
Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany. swillis@ukaachen.de
Hölzl
F
F
Wein
B
B
von Felbert
V
V
Fackeldey
V
V
Schumpelick
V
V
D001003:Anal Canal / Q000000981:diagnostic imaging; D000818:Animals; D003672:Defecation / Q000502:physiology*; D004285:Dogs; D004576:Electromyography; D005769:Gastrointestinal Motility; D008365:Manometry; D016737:Proctocolectomy, Restorative; D011859:Radiography