Unusual lability of 5'-O-tert-butyldimethylsilyl group on 4''-acyl TSAO derivatives.
de Castro
Sonia
S
Instituto de Química Médica (C.S.I.C.), Madrid, Spain.
Pérez-Pérez
María-Jesús
MJ
Lobatón
Esther
E
De Clercq
Erik
E
Balzarini
Jan
J
Camarasa
María-José
MJ
Velázquez
Sonsoles
S
D024882:Drug Resistance, Viral; D015497:HIV-1 / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000737:chemistry; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D013141:Spiro Compounds / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013936:Thymidine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology*
C102279:1-(2',5'-bis-O-(t-butyldimethylsilyl)ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)-3-ethylthymine; D017646:Organosilicon Compounds; D018894:Reverse Transcriptase Inhibitors; D013141:Spiro Compounds; C009660:t-butyldimethylsilyl compounds; D013936:Thymidine