title: Social deprivation and poor access to care as risk factors for severe pre-eclampsia.
abstract: OBJECTIVE
  To estimate the associations between biomedical, social and health care factors and the occurrence of severe pre-eclampsia, eclampsia or HELLP syndrome.
  
  
  METHODS
  A case-control study conducted in 14 of the 15 maternity hospitals of Brussels. Cases were all 99 women who delivered in these hospitals in 1996 and who had severe pre-eclampsia, eclampsia or HELLP syndrome. Controls were 200 women without these severe maternal conditions, randomly selected among women who delivered in the same hospitals during the same period. Crude odds ratios were computed and adjusted odds ratios were derived from logistic regression.
  
  
  RESULTS
  Indicators of social deprivation such as low educational level, poverty and illegal residence or asylum request, were strongly associated with the outcome in univariate analysis. So were African or Turkish ethnicity, obesity, chronic hypertension and primiparity. Logistic regression showed that no access to national health insurance and history of residence in another country were strongly and independently associated with the outcome (adjusted odds ratio = 4.0 (95% confidence interval 1.1, 14.0) and 3.7 (95% confidence interval 1.9, 7.3), respectively).
  
  
  CONCLUSIONS
  The burden of pre-eclampsia is concentrated in socially disadvantaged women. Health services should be more responsive to the specific needs of these women. Low access to health care may contribute to the occurrence of severe pre-eclampsia in our setting.
authors.affiliation: Unité Santé Reproductive et Epidémiologie Périnatale, Ecole de Santé Publique, Université Libre de Bruxelles, Brussels, Belgium. edwige.haelterman@ulb.ac.be
authors.forename: Edwige
authors.initials: E
authors.lastname: Haelterman
authors.forename: Rikke
authors.initials: R
authors.lastname: Qvist
authors.forename: Patricia
authors.initials: P
authors.lastname: Barlow
authors.forename: Sophie
authors.initials: S
authors.lastname: Alexander
mesh_terms: D000328:Adult; D000349:Africa; D001530:Belgium / Q000208:ethnology; D016022:Case-Control Studies; D016001:Confidence Intervals; D004522:Educational Status; D004641:Emigration and Immigration; D005260:Female; D017359:HELLP Syndrome / Q000208:ethnology / Q000209:etiology; D006801:Humans; D016015:Logistic Models; D009765:Obesity / Q000150:complications; D010298:Parity; D011225:Pre-Eclampsia / Q000208:ethnology / Q000209:etiology*; D011247:Pregnancy; D011295:Prenatal Care; D012307:Risk Factors; D012959:Socioeconomic Factors; D014421:Turkey