title: Andropause: an old concept in new clothing.
abstract: There is increasing evidence that the common condition of hypogonadism in older men when associated with symptoms responds well to testosterone replacement. Over the last few years there has been a marked increase in the awareness and treatment of the andropause [137]. Long-term side effects of testosterone are uncertain with only eight people over 50 years having been studied for 10 years [138]. Testosterone needs to be considered a quality-of-life drug, similar to sildenafil, and at present it should be used only if it produces symptomatic improvement. There is a need for a men's health study to determine the long-term efficacy and safety of testosterone replacement in older persons.
authors.affiliation: GRECC, VA Medical Center, Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA. morley@slu.edu
authors.forename: John E
authors.initials: JE
authors.lastname: Morley
authors.forename: H Mitchell
authors.initials: HM
authors.lastname: Perry
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D002979:Climacteric / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013739:Testosterone / Q000097:blood / Q000502:physiology* / Q000627:therapeutic use
chemical_list: D013739:Testosterone