title: Synthesis and properties of oligonucleotides involving a perylene unit linked to a 2'-deoxyribose residue.
abstract: We report here the synthesis and binding properties of oligonucleotides involving a perylene unit linked to the anomeric position of a 2'-deoxyribose residue. Both anomers were separated and incorporated separately at either the 5'-end or the internal position of a pyrimidine sequence. In any case the presence of the perylene unit stabilizes the complexes formed with either the single or the double-stranded target.
authors.affiliation: Centre de Biophysique Moléculaire, UPR 4301 CNRS affiliated with the University of Orléans and with INSERM, Orléans Cedex, France.
authors.forename: Yves
authors.initials: Y
authors.lastname: Aubert
authors.forename: Ulysse
authors.initials: U
authors.lastname: Asseline
mesh_terms: D001483:Base Sequence; D004277:DNA, Single-Stranded / Q000737:chemistry; D003855:Deoxyribose / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D014992:Xylenes / Q000737:chemistry*
chemical_list: D004277:DNA, Single-Stranded; D009838:Oligodeoxyribonucleotides; D011108:Polymers; D014992:Xylenes; C011055:parylene; D003855:Deoxyribose