title: Phosphatidylcholine in the treatment of localized fat.
abstract: Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases. Recently, it has also been used in the treatment of localized fat deposits. We report on the authors' clinical experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat deposits, showing the clinical response and side-effects. Volunteers received phosphatidylcholine injections in several areas of localized fat deposits, with a minimum interval of one week and mean interval of 15 days between applications. Laboratory tests were performed during the period of the drug use. Clinical results reflect that phosphatidylcholine was efficacious in reducing the fatty pads in the treated areas, with few side effects. From the authors' point of view, the off-label use of phosphatidylcholine in the treatment of fatty pads and small areas of localized fat is safe, low cost, and effective.
authors.affiliation: Doris Hexsel Dermatologic Clinic, Porto Alegre, Brazil. dohexsel@zaz.com.br
authors.forename: Doris
authors.initials: D
authors.lastname: Hexsel
authors.forename: Marcio
authors.initials: M
authors.lastname: Serra
authors.forename: Rosemari
authors.initials: R
authors.lastname: Mazzuco
authors.forename: Taciana
authors.initials: T
authors.lastname: Dal'Forno
authors.forename: Debora
authors.initials: D
authors.lastname: Zechmeister
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects* / Q000473:pathology; D003357:Cosmetic Techniques; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D007267:Injections; D008067:Lipoma / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D008297:Male; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D010713:Phosphatidylcholines