Incidence and mechanism of late stent malapposition after phosphorus-32 radioactive stent implantation.
Late stent malapposition is a potential complication of intracoronary brachytherapy. The aim of our study was to determine the incidence and mechanism of late stent malapposition after implantation of phosphorus-32 radioactive stents. We analyzed 159 patients for de novo lesions after the implantation of phosphorus-32 radioactive stents. There were 15 late stent malappositions. The incidence of malapposition was higher in patients who received Hot-Ends Isostents. External elastic membrane expansion greater than plaque increase in malapposed segments was observed. Late stent malapposition is caused by a localized increase in external elastic membrane that is greater than the increase in plaque area; this is believed to be a dose-dependent phenomenon because it was more common with Hot-Ends Isostents.
Kalinczuk
Lukasz
L
Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA.
Pregowski
Jerzy
J
Mintz
Gary S
GS
Dilcher
Christian E
CE
Kotani
Jun-ichi
J
Kruk
Mariusz
M
Shah
Vivek M
VM
Canos
Daniel A
DA
Chan
Rosana C
RC
Weissman
Neil J
NJ
D001918:Brachytherapy / Q000009:adverse effects* / Q000379:methods; D003327:Coronary Disease / Q000532:radiotherapy*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004307:Dose-Response Relationship, Radiation; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use*; D015607:Stents / Q000009:adverse effects*; D018084:Ultrasonography, Interventional
D010761:Phosphorus Radioisotopes