Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).
Sienaert
R
R
Rega Institute for Medical Research, K.U. Leuven, Leuven, Belgium.
Naesens
L
L
Brancale
A
A
Carangio
A
A
Andrei
G
G
Snoeck
R
R
Van Kuilenburg
A
A
De Clercq
E
E
McGuigan
C
C
Balzarini
J
J
D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry* / Q000494:pharmacology; D001643:Bridged Bicyclo Compounds / Q000737:chemistry* / Q000494:pharmacology; D018259:Herpesvirus 1, Human / Q000187:drug effects; D018258:Herpesvirus 2, Human / Q000187:drug effects; D014645:Herpesvirus 3, Human / Q000187:drug effects*; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D009705:Nucleosides / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D001643:Bridged Bicyclo Compounds; C446025:Cf 1368; D006574:Heterocyclic Compounds, 2-Ring; D009705:Nucleosides