title: New nucleoside analogues for the recognition of pyrimidine-purine inversion sites.
abstract: A new nucleoside designed to enhance triplex stability has been synthesised in 15 steps starting from sugar 2. This pathway contains the sugar derivative 9 which is a useful intermediate for the introduction of other natural and unnatural bases into the 2'-aminoethoxy nucleoside containing scaffold.
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland. buchini@ioc.unibe.ch
authors.forename: Sabrina
authors.initials: S
authors.lastname: Buchini
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Leumann
mesh_terms: D001665:Binding Sites; D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
chemical_list: D009705:Nucleosides; D011687:Purines; D011743:Pyrimidines; D004247:DNA