title: Influence of chemical modification on enzyme inactivation kinetics and stability.
abstract: Enzymes are placed in different categories depending on the effect of chemical modification on their inactivation kinetics and residual activity. This is done using a series-type mechanism involving degraded but stable enzyme states. The major distinction in the three basic categories is the effect of modification on residual activity. Each category is further sub-divided depending on the effect of modification on the values of the deactivation rate constants. The classification provides for a framework for comparison of a wide variety of enzyme deactivation data. Structure-function relations are provided wherever possible.
authors.affiliation: Chemical Engineering Department, University of Mississippi, MS 38677, USA.
authors.forename: A
authors.initials: A
authors.lastname: Sadana
authors.forename: J P
authors.initials: JP
authors.lastname: Henley