title: Moebius sequence and hypogonadotrophic hypogonadism.
abstract: A distinct form of Moebius sequence is associated with hypogonadotrophic hypogonadism. There have been five such cases to date. We now add a further case with detailed neurologic, endocrine, and autopsy findings and offer a hypothesis drawing parallels with the already established basis of hypogonadotrophic hypogonadism in the X-linked form of Kallman syndrome.
authors.affiliation: Our Lady's Hospital for Sick Children, National Centre for Medical Genetics, Crumlin, Dublin, Ireland.
authors.forename: Juliet E
authors.initials: JE
authors.lastname: Jennings
authors.forename: Colm
authors.initials: C
authors.lastname: Costigan
authors.forename: William
authors.initials: W
authors.lastname: Reardon
mesh_terms: D003389:Cranial Nerve Diseases / Q000175:diagnosis; D006065:Gonadotropins, Pituitary / Q000172:deficiency*; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis*; D007223:Infant; D007231:Infant, Newborn; D017436:Kallmann Syndrome / Q000175:diagnosis; D008297:Male; D020331:Mobius Syndrome / Q000175:diagnosis*
chemical_list: D006065:Gonadotropins, Pituitary