The detection of anti-Candida antibodies on experimental animal models.
The levels of anti-Candida antibodies were determined in experimental animals immunized with 4 different yeast doses (0.3, 0.6, 1.2, 2.4 x 10(8) CFU) at weekly intervals. After immunization (sampling intervals 1, 2, and 3 months), the intravenous blood was examined for the presence of serum anti-Candida antibodies. After one month, the titers of anti-Candida antibodies reached 1:40-1: 1280 and remained at the same level after two months in the majority of animals; only in a few of them the titers increased or were detected de novo. After three months, when the animals were no longer immunized, a decreasing trend in antibody titers was detected in the majority of animals.
Pilipcinec
E
E
Department of Microbiology and Immunology, University of Veterinary Medicine, 041 81 Kosice, Slovakia.
Dorko
E
E
Tkáciková
L
L
Wantrubová
A
A
Bugarský
A
A
D000372:Agglutination Tests; D000818:Animals; D000908:Antibodies, Fungal / Q000097:blood*; D000946:Antigens, Fungal / Q000276:immunology*; D002176:Candida albicans / Q000276:immunology*; D005260:Female; D007114:Immunization; D051381:Rats; D017207:Rats, Sprague-Dawley
D000908:Antibodies, Fungal; D000946:Antigens, Fungal