title: Skip metastasis in osteosarcoma.
abstract: Skip metastasis is rare in high-grade osteosarcoma and indicates a very poor prognosis. The authors describe two patients who had high-grade osteosarcoma and skip metastasis. MRI detected the skip lesion in both patients, and both lesions were confirmed by histology. The patients were treated with adjuvant chemotherapy and radical surgical resection. Both are alive and free of disease 3 and 6 years from diagnosis.
authors.affiliation: Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, TX 75390-9063, USA. patrick.leavey@utsouthwestern.edu
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Leavey
authors.forename: Michael D
authors.initials: MD
authors.lastname: Day
authors.forename: Timothy
authors.initials: T
authors.lastname: Booth
authors.forename: Gerhard
authors.initials: G
authors.lastname: Maale
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000473:pathology* / Q000556:secondary*; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D012516:Osteosarcoma / Q000473:pathology*; D011379:Prognosis