Synthesis of an asymmetrically substituted AZA crown ether as metal and amino acid binding site in DNA conjugates.
Crown ether 4 as a receptor core for protonated primary amines such as amino acids has been synthesized and incorporated into oligodeoxynucleotides as dangling ends.
Vogel
Stefan
S
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark. snv@chem.sdu.dk
Rohr
Katja
K
Dahl
Otto
O
Wengel
Jesper
J
D000577:Amides / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001665:Binding Sites; D043844:Crown Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D008670:Metals / Q000737:chemistry; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D010756:Phosphoric Acids / Q000737:chemistry
D000577:Amides; D000596:Amino Acids; D001372:Aza Compounds; D043844:Crown Ethers; D008670:Metals; D009838:Oligodeoxyribonucleotides; D010756:Phosphoric Acids; D004247:DNA; C011067:phosphoramidic acid