title: Collagenolytic proteases from bacteria.
abstract: Collagen degradation occurs during various physiological and pathological conditions. However, only a limited number of proteases with unique characteristics can trigger collagen degradation. Until recently, practical applications of collagenolytic proteases from bacteria had not been considered because their functions in bacteria are closely related to pathogenicity. However, bacterial collagenolytic proteases have many interesting and useful features. This review focuses on the collagenolytic proteases from bacteria, in particular their molecular properties and practical applications.
authors.affiliation: Department of Applied Biochemistry, Kyoto Prefectural University, Shimogamo, Sakyo, 606-8522 Kyoto, Japan. kwatanab@kpu.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D001419:Bacteria / Q000201:enzymology*; D001665:Binding Sites; D020134:Catalytic Domain; D017364:Collagenases / Q000737:chemistry* / Q000378:metabolism* / Q000627:therapeutic use; D003546:Cysteine Endopeptidases / Q000737:chemistry / Q000378:metabolism; D008666:Metalloendopeptidases / Q000378:metabolism; D008970:Molecular Weight; D012697:Serine Endopeptidases / Q000737:chemistry / Q000378:metabolism
chemical_list: D012697:Serine Endopeptidases; D003546:Cysteine Endopeptidases; D017364:Collagenases; D008666:Metalloendopeptidases; C022510:thimet oligopeptidase