title: Efficacy of enamel matrix protein applied to spontaneous periodontal disease in two dogs.
abstract: Enamel matrix protein (EMP) was applied for regeneration of periodontal tissue in 2 dogs with spontaneous periodontal disease. Case 1 had bony resorption around the root and root apex of the maxillary fourth premolars. Case 2 had vertical resorption of bone between the mandibular first and second molars. A flap was formed in the buccal gingiva, and EMP was applied onto the surface of the exposed root. One or 4 months postoperatively, increased bone level and clinical attachment were recognized. EMP was therefore suggested to be effective to induce regeneration of periodontal tissues in the cases with periodontal disease.
authors.affiliation: Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Okumura
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kadosawa
authors.forename: Toru
authors.initials: T
authors.lastname: Fujinaga
mesh_terms: D000818:Animals; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D004285:Dogs; D005260:Female; D008297:Male; D010510:Periodontal Diseases / Q000000981:diagnostic imaging / Q000628:therapy / Q000662:veterinary*; D011859:Radiography; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins