Advances in celiac disease.
In recent years, it has become evident that CD is much more common than previously appreciated, with a prevalence of 0.5% to 1% in Western, Arabian, and Indian populations. The disease may be present without symptoms (silent CD) or may present with extraintestinal manifestations only. Increasing awareness of the many faces of CD will increase diagnosis rate. CD patients have a cure for their disease, named the gluten-free diet, but this curative measure is very hard to adhere to. With the new insights into the pathogenesis of CD, clinicians enter an era where new treatment modalities for CD may turn into reality.
Shamir
Raanan
R
Division of Pediatric Gastroenterology and Nutrition, Meyer Children's Hospital of Haifa, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Rambam Medical Center, POB 9602, Haifa 31096, Israel. shamirr@netvision.net.il
D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers; D002446:Celiac Disease / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005983:Glutens; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology / Q000473:pathology; D015995:Prevalence; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology; D011503:Transglutaminases / Q000276:immunology
D001323:Autoantibodies; D015415:Biomarkers; D006680:HLA Antigens; D005983:Glutens; D011503:Transglutaminases