title: Unruptured aneurysms with cranial nerve symptoms: efficacy of endosaccular Guglielmi detachable coil treatment.
abstract: OBJECTIVE
  To evaluate the efficacy of endosaccular Guglielmi detachable coil (GDC) treatment of unruptured aneurysms causing cranial nerve (CN) symptoms.
  
  
  METHODS
  Among a database of 218 patients whose aneurysms were treated using GDC, seven patients met the criteria for unruptured aneurysms presenting with symptoms and signs of CN palsy. Changes in CN symptoms before and after GDC treatment were reviewed.
  
  
  RESULTS
  Aneurysms were located in the internal carotid-posterior communicating artery (n=3), the basilar bifurcation (n=1) and the cavernous internal carotid artery (n=3). CN symptoms included ptosis (n=6), mydriasis (n=2), and extraocular muscle (EOM) disorder (CN III: n=4; CN VI: n=3). Overall, improvement or resolution of CN symptoms after treatment was noted in five patients. CN symptoms in cases involving small (</= =10 mm) and intradural aneurysms tended to respond better to GDC treatment. Ptosis was the initial symptom to show improvement, while EOM dysfunction responded least favourably.
  
  
  CONCLUSIONS
  GDC coil packing appears to be an appropriate treatment method for the relief of CN symptoms associated with intracranial aneurysms.
authors.affiliation: Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, South Korea. dikim@yumc.yonsei.ac.kr
authors.forename: Dong Joon
authors.initials: DJ
authors.lastname: Kim
authors.forename: Dong Ik
authors.initials: DI
authors.lastname: Kim
authors.forename: Seung Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Si Yeon
authors.initials: SY
authors.lastname: Kim
mesh_terms: D003389:Cranial Nerve Diseases / Q000209:etiology*; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000628:therapy*; D008875:Middle Aged