title: Comparison of the outcome in men and women with chronic heart failure.
abstract: Recent studies have suggested some gender-related differences in the incidence, quality of care, response to therapy, and outcome in heart failure patients. The majority of studies have proposed a better survival for women compared to men. However, the under-representation of women in clinical trials leads to some uncertainty regarding the survival benefit. Some data suggest the possibility that ACE-inhibitors may be less beneficial in women as compared to men. Beta-blockers seem to be effective both in women and men. Further studies are needed to clarify whether these differences may have a pathophysiological basis.
authors.affiliation: Divisione di Cardiologia Fondazione S. Maugeri Clinica del Lavoro e della Riabilitazione, IRCCS Istituto Scientifico di Pavia Via Ferrata, 8 27100 Pavia. copasich@fsm.it
authors.forename: Stefania
authors.initials: S
authors.lastname: De Feo
authors.forename: Cristina
authors.initials: C
authors.lastname: Opasich
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D016019:Survival Analysis; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors