Molecular characterization of a strain of group a streptococcus isolated from a patient with a psoas abscess.
We report the first case of a primary group A streptococcus (GAS) psoas abscess in a 31-year-old woman. The psoas abscess was preceded by an episode of acute pharyngitis. The M-protein gene (emm) and streptolysin S structural gene (sagA) were present in the isolate, with no significant amino acid differences from previously described sequences of M1 GAS isolates. Multilocus sequence typing (MLST) showed that the isolate belonged to MLST sequence type (MLST-ST) 28, the predominant MLST-ST associated with invasive disease caused by M1 isolates.
Lau
Susanna K P
SK
Department of Microbiology, The University of Hong Kong, Hong Kong.
Woo
Patrick C Y
PC
Yim
Tak-ching
TC
To
Amanda P C
AP
Yuen
Kwok-yung
KY
D000328:Adult; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001426:Bacterial Proteins; D015373:Bacterial Typing Techniques; D002352:Carrier Proteins / Q000235:genetics; D004275:DNA, Ribosomal / Q000032:analysis; D005260:Female; D006801:Humans; D008969:Molecular Sequence Data; D016659:Psoas Abscess / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D013301:Streptolysins / Q000235:genetics
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D013301:Streptolysins; C014689:streptococcal M protein; C026050:streptolysin S