Intermediates released from a polyether-producing polyketide synthase provide insight into the mechanism of oxidative cyclization.
Hughes-Thomas
Zoë A
ZA
Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
Stark
Christian B W
CB
Böhm
Ines U
IU
Staunton
James
J
Leadlay
Peter F
PF
D003500:Cyclization; D007476:Ionophores / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure; D008985:Monensin / Q000096:biosynthesis* / Q000737:chemistry; D009097:Multienzyme Complexes / Q000378:metabolism*; D010084:Oxidation-Reduction
D007476:Ionophores; D009097:Multienzyme Complexes; D008985:Monensin