title: [Acidic stress in bacteria].
abstract: Information on acidic stress in bacteria, studied not only on the phenomenological, but also molecular and genetic levels, are systematized. Acidic stress in bacteria, appearing as the result of the acidification of the medium, is characterized by many events on the level of gene regulation. An increased expression of some genes and a decreased expression of others result in growth deceleration, quantitative and qualitative changes in the synthesis of proteins. Some of the newly synthesized proteins ensure the survival of bacteria in a medium with higher acidity and their protection from other stresses. The applied importance of acidic stress is relevant to some aspects of biotechnology, immunobiology and medicine.
authors.affiliation: Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Basnak'ian
mesh_terms: D000222:Adaptation, Physiological; D001419:Bacteria / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D003470:Culture Media; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D006863:Hydrogen-Ion Concentration
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media