Chemical incorporation of 1-methyladenosine, minor tRNA component, into oligonucleotides.
The synthesis of suitably protected 1-methyladenosine derivatives has been developed and its successful chemical incorporation into oligonucleotides was achieved.
Efimtseva
E V
EV
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Mikhailov
S N
SN
Rozenski
J
J
Busson
R
R
Van Aerschot
A
A
Herdewijn
P
P
D000241:Adenosine / Q000031:analogs & derivatives*; D007202:Indicators and Reagents; D009843:Oligoribonucleotides / Q000138:chemical synthesis*; D012343:RNA, Transfer / Q000737:chemistry*
D007202:Indicators and Reagents; D009843:Oligoribonucleotides; C002230:1-methyladenosine; D012343:RNA, Transfer; D000241:Adenosine