title: Lessons learned from interlaboratory comparisons of bioassay data interpretation.
abstract: When a set of bioassay data is given to two different dosimetrists, it is likely that these data will be interpreted differently, that different methods and dosimetric models will be applied and therefore different numerical values will be obtained. Thus, it is important for laboratories dealing with internal dosimetry to undergo performance testing procedures such as interlaboratory comparisons of bioassay data interpretation. Several intercomparison exercises have already been organised at national and international levels. The largest one so far was the 3rd European Intercomparison Exercise on Internal Dose Assessment, which has been organised in the framework of the EULEP/EURADOS Action Group, 'Derivation of parameter values for application to the new model of the human respiratory tract for occupational exposure'. The most important lesson learned from these intercomparison exercises was the need to develop agreed guidelines for internal dose evaluation procedures to promote harmonisation of assessments between organisations and countries.
authors.affiliation: Forschungszentrum Karlsruhe GmbH, Karlsruhe, Germany. hans.doerfel@hs.fzk.de
authors.forename: H
authors.initials: H
authors.lastname: Doerfel
authors.forename: A
authors.initials: A
authors.lastname: Andrasi
authors.forename: M
authors.initials: M
authors.lastname: Bailey
authors.forename: V
authors.initials: V
authors.lastname: Berkovski
authors.forename: C M
authors.initials: CM
authors.lastname: Castellani
authors.forename: C
authors.initials: C
authors.lastname: Hurtgen
authors.forename: J R
authors.initials: JR
authors.lastname: Jourdain
authors.forename: B
authors.initials: B
authors.lastname: LeGuen
mesh_terms: D019985:Benchmarking / Q000379:methods*; D003198:Computer Simulation; D003299:Cooperative Behavior; D005060:Europe; D006801:Humans; D007373:Interinstitutional Relations; D008954:Models, Biological; D015588:Observer Variation; D016273:Occupational Exposure / Q000032:analysis; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods / Q000592:standards* / Q000706:statistics & numerical data; D011848:Radioactive Pollutants / Q000032:analysis; D011868:Radioisotopes / Q000032:analysis* / Q000493:pharmacokinetics*; D011874:Radiometry / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D011848:Radioactive Pollutants; D011868:Radioisotopes