title: Relation between microvolt-level T-wave alternans and cardiac sympathetic nervous system abnormality using iodine-123 metaiodobenzylguanidine imaging in patients with idiopathic dilated cardiomyopathy.
abstract: We examined the relation between microvolt-level T-wave alternans and cardiac sympathetic nervous system abnormality using iodine-123 metaiodobenzylguanidine imaging in patients with idiopathic dilated cardiomyopathy. Our results strongly indicate that cardiac sympathetic denervation and accelerated sympathetic nervous activity play important roles in the presence of microvolt-level T-wave alternans in patients with idiopathic-dilated cardiomyopathy.
authors.affiliation: Division of Cardiovascular Medicine, Department of Medical Bioregulation, Yamaguchi University School of Medicine, Yamaguchi, Ube, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Harada
authors.forename: Akihiko
authors.initials: A
authors.lastname: Shimizu
authors.forename: Mariko
authors.initials: M
authors.lastname: Murata
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ono
authors.forename: Makoto
authors.initials: M
authors.lastname: Kubo
authors.forename: Reo
authors.initials: R
authors.lastname: Mitani
authors.forename: Yuka
authors.initials: Y
authors.lastname: Dairaku
authors.forename: Tomo
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Yamagata
authors.forename: Kouzaburou
authors.initials: K
authors.lastname: Seki
authors.forename: Masunori
authors.initials: M
authors.lastname: Matsuzaki
mesh_terms: D019797:3-Iodobenzylguanidine; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004562:Electrocardiography / Q000379:methods*; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000294:innervation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013564:Sympathetic Nervous System / Q000000981:diagnostic imaging / Q000503:physiopathology*
chemical_list: D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine