title: Levels of PCDDs, PCDFs and Co-PCBs in human milk in Saitama, Japan, and epidemiological research.
abstract: From 1998 to 2000, the dioxin levels were measured in the milk of 299 mothers who lived in Saitama prefecture, Japan. Factors that influenced the dioxin levels were investigated based on a questionnaire given to the milk donors at that time. It was found that the dioxin levels in the milk of the mothers who smoked were lower than those of non-smokers, and the dioxin levels were generally low in the mothers who were heavy smokers. The average dioxin levels in the milk of mothers who had been breast-fed were higher than those given formula, and there was a significant difference in the dioxin congeners. It was also found that the dioxin levels in milk of the women who regularly consumed fish and shellfish were generally higher. There was a strong correlation between summation operator TEQ and PCB126. The data suggested that PCB126 could be a useful indicator for the simplified analysis of dioxin in human milk.
authors.affiliation: Dioxin Research Group, Saitama Institute of Public Health, 639-1, Kamiokubo, Sakura-ku, Saitama 338-0824, Japan. ao167006@pref.saitama.jp
authors.forename: Mikiko
authors.initials: M
authors.lastname: Takekuma
authors.forename: Koichi
authors.initials: K
authors.lastname: Saito
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ogawa
authors.forename: Ryuji
authors.initials: R
authors.lastname: Matumoto
authors.forename: Susumu
authors.initials: S
authors.lastname: Kobayashi
mesh_terms: D000328:Adult; D001572:Benzofurans / Q000032:analysis*; D000072338:Dibenzofurans, Polychlorinated; D004032:Diet; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008895:Milk, Human / Q000737:chemistry*; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis*; D012907:Smoking
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins; D011078:Polychlorinated Biphenyls