title: Direct laparoscopic venous sampling to diagnose a small Sertoli-Leydig tumor.
abstract: BACKGROUND
  Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor.
  
  
  METHODS
  A 14-year-old female presented with hyperandrogenic complaints and an increased serum testosterone. Ovarian origin was confirmed by direct laparoscopic ovarian blood sampling. A right salpingo-oophorectomy was performed. The pathological diagnosis was SLCT of intermediate differentiation. Three years later, the patient presented again with an increased serum testosterone. A solid tumor in the left ovary was excised. The pathology was SLCT of intermediate differentiation. The patient remains disease-free.
  
  
  CONCLUSIONS
  Direct laparoscopic venous sampling is used to diagnose a small SLCT in a teenage patient.
authors.affiliation: Department of Obstetrics/Gynecology, Arnold Palmer Hospital, Orlando Regional Healthcare System, Orlando, FL 32806, USA.
authors.forename: L C
authors.initials: LC
authors.lastname: White
authors.forename: K D
authors.initials: KD
authors.lastname: Buchanan
authors.forename: T D
authors.initials: TD
authors.lastname: O'Leary
authors.forename: S J
authors.initials: SJ
authors.lastname: Carlan
authors.forename: R
authors.initials: R
authors.lastname: Boothby
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D010535:Laparoscopy; D016609:Neoplasms, Second Primary / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010052:Ovariectomy; D018310:Sertoli-Leydig Cell Tumor / Q000098:blood supply / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery