title: Efficacy and impact of monophasic versus biphasic countershocks for transthoracic cardioversion of persistent atrial fibrillation.
abstract: This report compares the cumulative efficacy of cardioversion and skeletal muscle injury after either damped sine wave monophasic or truncated exponential biphasic transthoracic cardioversion of persistent atrial fibrillation. The trial sought to refute the null hypothesis of therapeutic equivalence between monophasic and biphasic waveforms. Results of the study reveal similar cumulative efficacy of waveforms and greater levels of skeletal muscle damage when patients are younger and male, and when monophasic waveforms are used.
authors.affiliation: Department of Cardiology, Celje General Hospital, Celje, Slovenia. mmarinsek@hotmail.com
authors.forename: Matej
authors.initials: M
authors.lastname: Marinsek
authors.forename: Gregory Luke
authors.initials: GL
authors.lastname: Larkin
authors.forename: Petra
authors.initials: P
authors.lastname: Zohar
authors.forename: Mojca
authors.initials: M
authors.lastname: Bervar
authors.forename: Mojca
authors.initials: M
authors.lastname: Pekolj-Bicanic
authors.forename: Franciska Skrabl
authors.initials: FS
authors.lastname: Mocnik
authors.forename: Marko
authors.initials: M
authors.lastname: Noc
authors.forename: Matej
authors.initials: M
authors.lastname: Podbregar
mesh_terms: D000367:Age Factors; D000368:Aged; D001281:Atrial Fibrillation / Q000628:therapy*; D001835:Body Weight; D003402:Creatine Kinase / Q000097:blood*; D004554:Electric Countershock / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D018482:Muscle, Skeletal / Q000293:injuries* / Q000378:metabolism*; D009211:Myoglobin / Q000378:metabolism*; D011237:Predictive Value of Tests; D012737:Sex Factors
chemical_list: D009211:Myoglobin; D003402:Creatine Kinase