Loss of an MDR transporter in compact stalks of maize br2 and sorghum dw3 mutants.
Agriculturally advantageous reduction in plant height is usually achieved by blocking the action or production of gibberellins. Here, we describe a different dwarfing mechanism found in maize brachytic2 (br2) mutants characterized by compact lower stalk internodes. The height reduction in these plants results from the loss of a P-glycoprotein that modulates polar auxin transport in the maize stalk. The sorghum ortholog of br2 is dwarf3 (dw3), an unstable mutant of long-standing commercial interest and concern. A direct duplication within the dw3 gene is responsible for its mutant nature and also for its instability, because it facilitates unequal crossing-over at the locus.
Multani
Dilbag S
DS
Pioneer Hi-Bred International, 7250 Northwest 62nd Avenue, Johnston, IA 50131, USA.
Briggs
Steven P
SP
Chamberlin
Mark A
MA
Blakeslee
Joshua J
JJ
Murphy
Angus S
AS
Johal
Gurmukh S
GS
D018435:ATP Binding Cassette Transporter, Subfamily B / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D001692:Biological Transport; D003001:Cloning, Molecular; D003434:Crossing Over, Genetic; D020440:Gene Duplication; D017343:Genes, Plant; D005808:Genes, Recessive; D007210:Indoleacetic Acids / Q000378:metabolism*; D008027:Light; D008969:Molecular Sequence Data; D009154:Mutation; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D018547:Plant Stems / Q000166:cytology / Q000378:metabolism; D006109:Poaceae / Q000166:cytology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D011995:Recombination, Genetic; D003313:Zea mays / Q000166:cytology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*
D018435:ATP Binding Cassette Transporter, Subfamily B; D007210:Indoleacetic Acids; D010940:Plant Proteins; C030737:indoleacetic acid