[Betaxolol for prevention of steroid induced intraocular pressure elevations in patients after radial keratotomy].
OBJECTIVE
To investigate the effect of 0.25% betaxolol (Betoptic S) in the normal myopia eye, on steroid-induced intraocular pressure (IOP) elevations in patients undergoing radial keratotomy.


METHODS
Radial keratotomy was performed on 27 patients (43 eyes). All these patients during the period of 3 months after surgery were treated with 0.1% dexamethasone drops in decreasing doses and 0.25% betaxolol (Betoptic S) drops twice a day. Ophthalmic examination and IOP measurements were made on 1, 2, 3, 14, 30, 60 day after operation.


RESULTS
During 3 months of postoperative period 27.9% of eyes had IOP exceeding 25 mm Hg, or had an increase of IOP of 10 mm Hg or more.


CONCLUSIONS
The results of the current study and the study published by the author previously lead to conclusion, that 0.25% betaxolol (Betoptic S) in the normal myopia eye, decreases the risk of steroid-induced IOP elevation in patients after radial keratotomy, but does not prevent it.
Kałuzny
Bartłomiej J
BJ
Kliniki Okulistycznej Akademii Medycznej w Bydgoszczy.
D000328:Adult; D015784:Betaxolol / Q000008:administration & dosage*; D015715:Corneal Edema / Q000209:etiology / Q000517:prevention & control; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007646:Keratotomy, Radial / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000139:chemically induced* / Q000188:drug therapy / Q000517:prevention & control*; D009883:Ophthalmic Solutions / Q000009:adverse effects
D009883:Ophthalmic Solutions; D003907:Dexamethasone; D015784:Betaxolol