Serial granulocyte transfusions as a treatment for sepsis due to multidrug-resistant Pseudomonas aeruginosa in a neutropenic patient.
The emergence of multidrug-resistant Pseudomonas aeruginosa (MRPA) has become a major clinical problem. We successfully treated MRPA sepsis in a neutropenic patient undergoing peripheral blood stem cell transplantation with serial granulocyte transfusions. Granulocyte transfusion should be considered as a treatment for severe infection in patients with neutropenia.
Lin
Ying-Wei
YW
Department of Pediatrics, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. linying@mail.nih.gov
Adachi
Souichi
S
Watanabe
Ken-Ichiro
K
Umeda
Katsutsugu
K
Nakahata
Tatsutoshi
T
D016470:Bacteremia / Q000382:microbiology* / Q000628:therapy*; D002648:Child; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006098:Granulocytes; D006801:Humans; D017708:Leukocyte Transfusion; D009503:Neutropenia / Q000150:complications; D011552:Pseudomonas Infections / Q000382:microbiology / Q000628:therapy; D011550:Pseudomonas aeruginosa / Q000187:drug effects*