title: Optimization of antiviral prodrug properties using combinatorial methods.
abstract: Some diacid biodegradable synthesis of aziduthymidine (AZT) were synthesized and applied to production of about 60 different derivatives.
authors.affiliation: Department of Biotechnology, Moscow Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia. julia_ber@rambler.ru
authors.forename: Yulia V
authors.initials: YV
authors.lastname: Berezovskaya
authors.forename: Mikhail V
authors.initials: MV
authors.lastname: Chudinov
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Yurkevich
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D007202:Indicators and Reagents; D011355:Prodrugs / Q000138:chemical synthesis*; D015215:Zidovudine / Q000031:analogs & derivatives / Q000138:chemical synthesis
chemical_list: D000998:Antiviral Agents; D007202:Indicators and Reagents; D011355:Prodrugs; D015215:Zidovudine