Update in the pathologic features of mature B-cell and T/NK-cell leukemias.
Modern diagnosis of mature B- and T-cell leukemias requires integration of morphologic, immunophenotypic, and molecular genetic features. This integrative approach has allowed more precise definitions of specific disease entities. This in turn provides better information for clinicians to select proper therapy and determine prognosis. The characteristic pathologic features of these disorders are reviewed.
Hsi
Eric D
ED
Department of Clinical Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. hsie@ccf.org
Mirza
Imran
I
D001853:Bone Marrow / Q000276:immunology / Q000473:pathology*; D002869:Chromosome Aberrations; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D015458:Leukemia, T-Cell / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D008967:Molecular Biology