title: Pre-exposure chemoprophylaxis (PREP) as an HIV prevention strategy.
abstract: Chemoprophylaxis may be a prevention strategy for the sexual transmission of human immunodeficiency virus (HIV). Evidence suggests that condom use has waned with the availability of antiretroviral medication, at least in some resource-rich settings. Barrier methods of HIV prevention have inherent problems, and the potential for failure. Microbicide research has focused primarily on male-to-female transmission. Analogous to post-exposure prophylaxis, HIV prevention may be achieved by pre-exposure prophylaxis in some settings. Research in this potential strategy may be rewarding.
authors.affiliation: Royal Free Centre for HIV Medicine, Royal Free Hospital, Pond Street, London NW3 2QG. myoule@rfh1.demon.co.uk
authors.forename: Mike
authors.initials: M
authors.lastname: Youle
authors.forename: Mark A
authors.initials: MA
authors.lastname: Wainberg
mesh_terms: D044966:Anti-Retroviral Agents / Q000008:administration & dosage*; D018890:Chemoprevention; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans
chemical_list: D044966:Anti-Retroviral Agents