Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.
Wu
Chung-Yi
CY
The Genomics Research Center and, Institute of Biological Chemistry, Academia Sinica, No. 128 Academia Road Section 2, Nan-Kang, Taipei, 11529, Taiwan.
Chang
Chuan-Fa
CF
Chen
Jenny Szu-Yu
JS
Wong
Chi-Huey
CH
Lin
Chun-Hung
CH
D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005944:Glucosamine / Q000031:analogs & derivatives / Q000737:chemistry; D015394:Molecular Structure; D005644:alpha-L-Fucosidase / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004791:Enzyme Inhibitors; C483525:fuconojirimycin; D017485:1-Deoxynojirimycin; D005644:alpha-L-Fucosidase; D005944:Glucosamine