Iron and Parkinson's disease: chelators to the rescue?
The essential metal iron has long been implicated in the neuronal damage associated with Parkinson's disease. Recent findings show that iron chelation may prevent the reductions in dopamine and motor disturbances associated with this disease, and suggest the need to examine the role of dietary iron and the use of metal chelators in neurodegenerative disorders.
Levenson
Cathy W
CW
Florida State University, Program in Neuroscience, Department of Nutrition, Food and Exercise Sciences, Tallahassee, FL 32306-4340, USA.
D006801:Humans; D007501:Iron / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000378:metabolism* / Q000627:therapeutic use; D009410:Nerve Degeneration; D018696:Neuroprotective Agents / Q000627:therapeutic use; D010300:Parkinson Disease / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*
D007502:Iron Chelating Agents; D018696:Neuroprotective Agents; D007501:Iron