title: Desmoid tumors: a clinical review of 30 patients with more than 20 years' follow-up.
abstract: We retrospectively studied the outcome in a consecutive series of 30 patients with desmoid tumors who were followed for more than 20 years after treatment (surgery in 29 patients). A local recurrence occurred in 12 patients and more than 1 recurrence occurred in 8. 3 patients had spontaneous complete regression of the tumor. At follow-up after mean 28 (20-54) years, all patients were tumor-free except 1 who had had a stable tumor for at least 11 years. Symptoms were related more to treatment than to the tumor. We conclude that desmoid tumors may have a high capacity for self-limitation and that conservative therapy should be considered in symptom-free patients.
authors.affiliation: Gothenburg Musculoskeletal Tumor Center, Department of Orthopaedics, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden. mikael.dalén@orthop.gu.se
authors.forename: B P Mikael
authors.initials: BP
authors.lastname: Dalén
authors.forename: Peter M
authors.initials: PM
authors.lastname: Bergh
authors.forename: Björn U P
authors.initials: BU
authors.lastname: Gunterberg
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D018221:Fibromatosis, Abdominal / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D018222:Desmoid Tumors / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D012189:Retrospective Studies; D018570:Risk Assessment; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome