[Types of immune response in acute infectious diseases].
The author's concept on the system of self regulation of immune response is described. Four types of this response are proposed, which differ by total intensity of cytokine reaction, the development time as well as manifestation degree of non specific immunosuppression, and, most importantly, the profile of specific immune response to the antigens of the infective agent. These four types of immune response are closely linked with increased severity of clinical manifestations.
Zheleznikova
G F
GF
Research Institute of Child Infections, St. Petersburg, Russia.
D000208:Acute Disease; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D007107:Immune System / Q000276:immunology*; D007136:Immunoglobulins / Q000032:analysis; D007239:Infections / Q000276:immunology* / Q000378:metabolism; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D013997:Time Factors
D016207:Cytokines; D007136:Immunoglobulins