[Influence of folic acid in primary prevention of neural tube defects].
OBJECTIVE
The aim of the study was to analyze the incidence of neural tube defects in Lublin Province between 1990 and 2000 after application of primary prevention with folic acid.


METHODS
A total of 293,039 newborns were analyzed.


RESULTS
Neural tube defects were diagnosed in 53 newborns.


CONCLUSIONS
Reduction of frequency of meningocele was shown after application of primary prevention with folic acid in 1998. Meningoceles were most frequent in 1992 (1.32/1000) and in 1998 frequency of these defects was reduced and in 2000 was down to 0.62/1000 births.
Sawulicka-Oleszczuk
Henryka
H
Kliniki Połoznictwa i Patologii Ciazy AM w Lublinie.
Kostuch
Marzena
M
D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D009436:Neural Tube Defects / Q000453:epidemiology / Q000517:prevention & control*; D018696:Neuroprotective Agents / Q000008:administration & dosage*; D011044:Poland / Q000453:epidemiology; D011322:Primary Prevention / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome
D018696:Neuroprotective Agents; D005492:Folic Acid