title: Pituitary stalk metastasis from breast cancer treated with systemic chemotherapy.
abstract: We describe a 61-year-old woman with diabetes insipidus caused by a pituitary stalk metastasis from breast cancer. She had a medical history of breast conservation therapy for early breast cancer 5 years previously. Pituitary, lung, liver, bone and neck lymphnode metastases was revealed at the same time. She received systemic chemotherapy consisting of docetaxel and cisplatin. After chemotherapy MRI finding in pituitary gland was improved, lung and liver metastases also improved, however, symptoms of diabetes insipidus did not improve. She is alive, receiving endocrine treatment for 2 years, since onset of diabetes insipidus.
authors.affiliation: Department of Tumor Radiology, Program of Tumor Biology and Regulation, Kochi Medical School, Nankoku 783-8505, Kochi, Japan. muratay@kochi-ms.ac.jp
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Murata
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Isamu
authors.initials: I
authors.lastname: Yokoe
authors.forename: Shinji
authors.initials: S
authors.lastname: Kariya
authors.forename: Kazuo
authors.initials: K
authors.lastname: Morio
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Sasaki
authors.forename: Akihito
authors.initials: A
authors.lastname: Nishioka
authors.forename: Shoji
authors.initials: S
authors.lastname: Yoshida
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D001921:Brain / Q000473:pathology; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy*; D002945:Cisplatin / Q000627:therapeutic use; D003919:Diabetes Insipidus / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010911:Pituitary Neoplasms / Q000473:pathology / Q000556:secondary*; D043823:Taxoids / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin