title: Thrombolytic therapy for delayed, in-hospital stroke after cardiac surgery.
abstract: Five patients who had delayed stroke after cardiac surgery underwent intraarterial administration of a fibrinolytic agent for thromboembolism (n = 4) or thrombosis (n = 1) of the cerebral artery. Complete recanalization of the occluded artery was obtained in 3 patients and partial recanalization in 2. Additional angioplasty for basilar artery stenosis was performed in 1 patient. No patients exhibited rebleeding into the pericardial space or wound bleeding. All patients survived with moderate or full functional recovery. Immediate cerebral angiography and local thrombolysis may improve functional outcome and survival in patients with postcardiotomy cerebral thromboembolism.
authors.affiliation: Department of Surgery I, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan. ikuofuku@cc.hirosaki-u.ac.jp
authors.forename: Ikuo
authors.initials: I
authors.lastname: Fukuda
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Imazuru
authors.forename: Motoo
authors.initials: M
authors.lastname: Osaka
authors.forename: Ko
authors.initials: K
authors.lastname: Watanabe
authors.forename: Kotoo
authors.initials: K
authors.lastname: Meguro
authors.forename: Mitsuyosi
authors.initials: M
authors.lastname: Wada
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures; D002533:Cerebral Angiography; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
chemical_list: D005343:Fibrinolytic Agents; D014568:Urokinase-Type Plasminogen Activator