title: [Dynamic changes of platelet number in early multiple injury and it is effect on prognosis].
abstract: OBJECTIVE
  To study the dynamic changes of platelet number in early multiple injured patients and its clinical significance.
  
  
  METHODS
  Ninety patients with multiple injury less than 48 hours were selected. Blood analysis was dynamicly investigated at 1, 24, 72, 120 and 168 hours after in Hospital, and acute physiology and chronic health evaluation III (APACHE III) and injury seriousness scale (ISS) scores were recorded.
  
  
  RESULTS
  The platelet number declined after injury, reached the lowest point at 72 hours after in hospital, then restored to the normal level at 120 hours. In the platelet decrease group, the trauma was more critically[ISS (29.60+/-9.80) scores vs. (22.30+/-12.00) scores, (P<0.05)] and the incidence of multiple organs dysfunction syndrome (MODS) was higher than normal group (83.9% vs. 62.7%, P<0.05). In the death group, the number of platelet was declined[ (30.1+/-10.3) hours vs. (51.3+/-14.8) hours, (P<0.05) and the lasting tine was longer[ (63.7+/-11.0) hours vs. (54.2+/-13.4) hours, (P<0.05).
  
  
  CONCLUSIONS
  The platelet number declines after multiple injury. The decrease and continuously lower level of platelet suggest poor prognosis.
authors.affiliation: Kunming General Hospital, Chengdu Military Region, Kunming 650032, Yunnan, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Hao
authors.forename: Ming
authors.initials: M
authors.lastname: Lei
authors.forename: Yin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Chang-ju
authors.initials: CJ
authors.lastname: Sun
authors.forename: Ge-yuan
authors.initials: GY
authors.lastname: Bian
authors.forename: Li
authors.initials: L
authors.lastname: Bai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000502:physiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology; D009104:Multiple Trauma / Q000097:blood* / Q000150:complications; D010972:Platelet Activating Factor / Q000502:physiology; D010976:Platelet Count; D011379:Prognosis
chemical_list: D010972:Platelet Activating Factor