title: The treatment of Sjögren's syndrome with tibolone: a case report.
abstract: We report the successful treatment with tibolone of a postmenopausal woman affected by primary Sjögren's syndrome. One year after the beginning of treatment, the woman does not need artificial tears and vaginal lubricants. This is the first report of an effective pharmacologic treatment for primary Sjögren's syndrome in humans.
authors.affiliation: Department of Obstetrics and Gynecology, University of Trieste, Istituto di Recerca e Cura a Carettere Scientifico Burlo Garofolo, Trieste, Italy. sartore@burlo.trieste.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Sartore
authors.forename: Eva
authors.initials: E
authors.lastname: Grimaldi
authors.forename: Secondo
authors.initials: S
authors.lastname: Guaschino
mesh_terms: D020847:Estrogen Receptor Modulators / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009652:Norpregnenes / Q000627:therapeutic use*; D017698:Postmenopause; D012859:Sjogren's Syndrome / Q000188:drug therapy*
chemical_list: D020847:Estrogen Receptor Modulators; D009652:Norpregnenes; C027385:tibolone