title: Recognition of cyclonucleoside lesions by the Lactococcus lactis FPG protein.
abstract: Several purine and pyrimidine cyclonucleosides were found to be not recognized by several Escherichia coli and yeast DNA N-glycosylases. Interestingly, a non covalent complex was observed between the Lactoccocus lactis formamidopyrimidine-DNA glycosylases (Fpg-Ll) and the cyclonucleosides. This may provide new information on the mechanism involved in the activity of the latter enzyme.
authors.affiliation: Laboratoire des Lésions des Acides Nucléiques, Service de Chimie Inorganique et Biologique and UMR 5046, DRFMC-CEA/Grenoble, Grenoble, France.
authors.forename: Evelyne
authors.initials: E
authors.lastname: Muller
authors.forename: Didier
authors.initials: D
authors.lastname: Gasparutto
authors.forename: Bertrand
authors.initials: B
authors.lastname: Castaing
authors.forename: Alain
authors.initials: A
authors.lastname: Favier
authors.forename: Jean
authors.initials: J
authors.lastname: Cadet
mesh_terms: D004249:DNA Damage; D004269:DNA, Bacterial / Q000235:genetics; D043382:DNA-Formamidopyrimidine Glycosylase / Q000378:metabolism*; D013294:Lactococcus lactis / Q000201:enzymology* / Q000235:genetics; D009705:Nucleosides / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D012263:Ribonucleosides / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D009705:Nucleosides; D009838:Oligodeoxyribonucleotides; D012263:Ribonucleosides; D043382:DNA-Formamidopyrimidine Glycosylase