title: Chordae tendineae rupture resulting in pulmonary edema in a patient with discrete subvalvular aortic stenosis--a case report and literature review.
abstract: This report concerns an apparently healthy elderly woman who presented with gradually worsening mitral regurgitation secondary to chordae tendineae rupture leading to pulmonary edema in the presence of discrete subvalvular aortic stenosis with a severe gradient reflecting the left ventricular outflow tract obstruction. The gradual worsening of heart failure took place parallel to the increase in severity of mitral regurgitation in a short period. The patient underwent successful mitral valve replacement with myectomy. Surgical inspection revealed rupture of the chordae tendineae to the posterior leaflets without any significant primary intrinsic disease of the mitral valve. The predominant mechanism of chordae tendineae rupture in this patient with discrete subvalvular aortic stenosis is a severe pressure gradient. It is suggested that increased awareness of chordae tendineae rupture as a cause of mitral regurgitation and the prompt use of appropriate diagnostic tools may facilitate the timely recognition of this potentially fatal, but treatable, cause of mitral regurgitation in patients with left ventricular outflow tract obstruction.
authors.affiliation: Division of Cardiology, Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA, USA.
authors.forename: O
authors.initials: O
authors.lastname: Adler
authors.forename: S
authors.initials: S
authors.lastname: Kalidindi
authors.forename: A
authors.initials: A
authors.lastname: Butt
authors.forename: K M A
authors.initials: KM
authors.lastname: Hussain
mesh_terms: D000368:Aged; D001020:Aortic Stenosis, Subvalvular / Q000150:complications*; D005260:Female; D006341:Heart Rupture / Q000150:complications*; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000209:etiology; D011654:Pulmonary Edema / Q000209:etiology*