title: Model of reversible cerebral ischemia in a monkey model.
abstract: We have developed a model of reversible cerebral ischemia in a high-level nonhuman primate. By using endovascular techniques, the posterior cerebral artery is permanently occluded with coils, and the ipsilateral middle cerebral artery is temporarily occluded with a balloon. The balloon can be deflated and/or removed to reestablish flow at precise time intervals. Functional imaging of the brain can be performed during occlusion and reperfusion, since the balloon can be deflated or removed in a scanner.
authors.affiliation: Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA.
authors.forename: Charles A
authors.initials: CA
authors.lastname: Jungreis
authors.forename: Edwin
authors.initials: E
authors.lastname: Nemoto
authors.forename: Fernando
authors.initials: F
authors.lastname: Boada
authors.forename: Michael B
authors.initials: MB
authors.lastname: Horowitz
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000175:diagnosis / Q000628:therapy; D002533:Cerebral Angiography; D004195:Disease Models, Animal; D008254:Macaca nemestrina