Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL.
Appel
I M
IM
Pinheiro
J P V
JP
den Boer
M L
ML
Lanvers
C
C
Reniers
N C M
NC
Boos
J
J
Pieters
R
R
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001215:Asparaginase / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D001216:Asparagine / Q000134:cerebrospinal fluid* / Q000172:deficiency; D002648:Child; D006801:Humans; D007275:Injections, Intravenous; D008657:Metabolic Clearance Rate; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000134:cerebrospinal fluid* / Q000188:drug therapy*; D013997:Time Factors
D000970:Antineoplastic Agents; D011092:Polyethylene Glycols; D001216:Asparagine; C042705:pegaspargase; D001215:Asparaginase