title: Distribution of variant genotypes of Fc gamma receptor IIIa in healthy Chinese population of Zhengzhou City.
abstract: To investigate the distribution of variant genotypes of Fc gamma receptor IIIa (Fc gamma R IIIa) in healthy Chinese population of Zhengzhou city, genomic DNA was extracted from peripheral blood of healthy donators. The genotypes of Fc gamma R IIIa-158 were determined by nested polymerase chain reaction (PCR) in 137 healthy people in Zhengzhou city. The results showed that frequencies of variant genotypes FF, VV and VF were 42.3%, 48.9% and 8.8% respectively. The distribution of Fc gamma R IIIa-158 in healthy Chinese population of Zhengzhou city was polymorphic and different from that of African Americans (AA) and Caucasian Americans (CA).
authors.affiliation: Department of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Jianfei
authors.initials: J
authors.lastname: Feng
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Hu
authors.forename: Bin
authors.initials: B
authors.lastname: Luan
authors.forename: Weihai
authors.initials: W
authors.lastname: Yue
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.forename: Shaoxian
authors.initials: S
authors.lastname: Zhu
authors.forename: Yumei
authors.initials: Y
authors.lastname: Xu
mesh_terms: D044466:Asian People; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017452:Receptors, IgG / Q000235:genetics*; D044465:White People
chemical_list: D017452:Receptors, IgG