Epidemiological study of resistance to nalidixic acid and other antibiotics in clinical Yersinia enterocolitica O:3 isolates.
Forty-six Yersinia enterocolitica O:3 clinical isolates resistant to nalidixic acid were studied. The use of molecular typing techniques, other indicators of resistance patterns, the plasmid profile, and the presence of genes that encode aminoglycoside-modifying enzyme production suggested to us a clonal dissemination of the studied strains.
Capilla
S
S
Department of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.
Goñi
P
P
Rubio
M C
MC
Castillo
J
J
Millán
L
L
Cerdá
P
P
Sahagún
J
J
Pitart
C
C
Beltrán
A
A
Gómez-Lus
R
R
D000890:Anti-Infective Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology*; D009713:Nucleotidyltransferases / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D015009:Yersinia Infections / Q000453:epidemiology* / Q000382:microbiology; D015008:Yersinia enterocolitica / Q000187:drug effects* / Q000235:genetics
D000890:Anti-Infective Agents; D009268:Nalidixic Acid; D009713:Nucleotidyltransferases; C022678:streptomycin 3''-adenylyltransferase