[Immunochemical properties of free mu-chain protein in a patient with mu-heavy chain disease].
We report a case of mu-heavy chain disease. A 56-year-old woman presented with anemia and hemorrhagic diathesis. The serum of the patient was found to have free mu-heavy chain. The patient also had a kappa type-Bence Jones protein in serum and urine. Immunoelectrophoresis showed an abnormal precipitin line in the alpha 2-globulin region which reacted with antiserum to mu-chain but not with antiserum for light chains. The molecular weight of the monomer of the patient's mu-heavy chain protein was approximately 67,000 daltons less than that of the normal mu-heavy chain protein.
Tamura
Akiyo
A
Department of Clinical Laboratory, Kobe City General Hospital, Kobe 650-0046.
Yamashiro
Akiko
A
Mizutani
Fumiko
F
Oita
Tatsuo
T
Maeda
Akinori
A
Takahashi
Takayuki
T
D001536:Bence Jones Protein / Q000378:metabolism; D005260:Female; D006362:Heavy Chain Disease / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007148:Immunoglobulin mu-Chains / Q000097:blood / Q000276:immunology*; D008875:Middle Aged
D007148:Immunoglobulin mu-Chains; D001536:Bence Jones Protein