Enantiospecific formal total syntheses of (-)-salicylihalamides A and B from D-glucose and L-rhamnose.
[reaction: see text] Two formal chiral pool syntheses of the (-)-salicylihalamides A and B were achieved from commercially available 1,2,5,6-diacetone-d-glucose and l-rhamnose.
Yang
KyoungLang
K
Department of Medicinal Chemistry, Center for Cancer Experimental Therapeutics and Drug Discovery Program, Higuchi Biosciences Center, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045-7582, USA.
Haack
Torsten
T
Blackman
Burchelle
B
Diederich
Wibke E
WE
Roy
Subho
S
Pusuluri
Srinivas
S
Georg
Gunda I
GI
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis*; D005947:Glucose / Q000031:analogs & derivatives / Q000737:chemistry*; D015394:Molecular Structure; D012210:Rhamnose / Q000737:chemistry*; D013237:Stereoisomerism
D019086:Bridged Bicyclo Compounds, Heterocyclic; C410986:salicylihalamide A; D005947:Glucose; D012210:Rhamnose