title: Pergolide mesylate form II.
abstract: A new polymorph of pergolide mesylate or 8beta-[(methylsulfanyl)methyl]-6-propylergoline methanesulfonate, C(19)H(27)N(2)S(+).CH(3)SO(3)(-), is reported. Pergolide mesylate form II crystallizes in the trigonal system, which is unique for ergot derivatives. Although the hydrogen-bond system in form II differs completely from that in form I, the conformation of the pergolide moiety in various related structures is very similar.
authors.affiliation: IVAX Pharmaceuticals sro, Research Unit, Branisovská 31, 370 05 Ceské Budejovice, Czech Republic. alexandr_jegorov@ivax-cz.com
authors.forename: Alexandr
authors.initials: A
authors.lastname: Jegorov
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Horák
authors.forename: Jan
authors.initials: J
authors.lastname: Cejka
authors.forename: Bohumil
authors.initials: B
authors.lastname: Kratochvíl
authors.forename: Ivana
authors.initials: I
authors.lastname: Císarová
mesh_terms: D000978:Antiparkinson Agents / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D010479:Pergolide / Q000737:chemistry*
chemical_list: D000978:Antiparkinson Agents; D010479:Pergolide