title: [Isolation of Penicillium DIERCKX 1901--a producer of diketopiperazine alkaloids rokefortin and 3,12-dihydrokefortin--from permafrost].
abstract: Secondary metabolites of the three strains of Penicillium aurantiogriseum, isolated from permafrost sediments, were identified. It was found that these fungi synthesized diketopiperazine alkaloids roquefortine and 3,12-dihydroroquefortine. The strain VKM FW-766 synthesized alkaloids in in the course of certain growth-related processes. When the strain was grown on a mineral medium, time courses of roquefortine and 3,12-dihydroroquefortine concentrations were characterized by biphasic curves.
authors.affiliation: Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Oblast, 142290 Russia. Kozlovski@ibpm.serpukhov.su
authors.forename: A G
authors.initials: AG
authors.lastname: Kozlovskiĭ
authors.forename: V P
authors.initials: VP
authors.lastname: Zhelifonova
authors.forename: V M
authors.initials: VM
authors.lastname: Adanin
authors.forename: T V
authors.initials: TV
authors.lastname: Antipova
authors.forename: S M
authors.initials: SM
authors.lastname: Szerskaia
authors.forename: N E
authors.initials: NE
authors.lastname: Ivanushkina
authors.forename: U
authors.initials: U
authors.lastname: Grafe
mesh_terms: D000470:Alkaloids / Q000096:biosynthesis*; D010407:Penicillium / Q000378:metabolism*
chemical_list: D000470:Alkaloids