Low molecular mass peptide dendrimers that express antimicrobial properties.
A series of low-generation dendrimeric peptides was synthesized in an attempt to evaluate their antimicrobial potency. All tested dendrimeric peptides in which lysine was a starting and branching element expressed moderate activity against Staphylococcus aureus NCTC 4163, and Escherichia coli NCTC 8196.
Janiszewska
Jolanta
J
Industrial Chemistry Research Institute, 01-793 Warsaw, Poland.
Swieton
Joanna
J
Lipkowski
Andrzej W
AW
Urbanczyk-Lipkowska
Zofia
Z
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000302:isolation & purification / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004926:Escherichia coli / Q000187:drug effects; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests; D010455:Peptides / Q000138:chemical synthesis* / Q000302:isolation & purification / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D007202:Indicators and Reagents; D010455:Peptides