Pathomorphological criteria of arrhythmogenic heart.
Pathomorphological criteria of arrhythmogenic heart include structural compartmentalization with primary changes in the right ventricle and interventricular septum, fibro- and lipomatosis of the myocardium, and disseminated coronary obstruction. Ischemic focuses in the conducting system are the site of formation of arrhythmogenic substance promoting the development and progression of cardiac arrhythmias. Cardioneuropathy and pathological motility of the interventricular septum lead to systolic dysfunction and contribute to asynchronous excitation and contraction of ventricles in arrhythmogenic heart.
Rozenberg
V D
VD
Department of General Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Nepomnyashchikh
L M
LM
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000473:pathology*; D006321:Heart / Q000033:anatomy & histology / Q000503:physiopathology*; D006346:Heart Septum / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia; D009206:Myocardium / Q000473:pathology*