title: Ophthalmological and biological features of the oculorespiratory syndrome after influenza vaccination.
abstract: We report the ophthalmological and laboratory findings of 6 patients who, after influenza vaccination, were affected by oculorespiratory syndrome (ORS), complaining of red eyes, photophobia, blurred vision, palpebral edema, ocular pain and itching, and conjunctival secretions. The conjunctivae were mildly hyperemic with few follicles, but the ophthalmological examination findings were otherwise normal. Patients had lymphopenia and decreased levels of the total hemolytic complement and the third and fourth component of the complement. We conclude that ORS causes conjunctivitis and seems to involve the complement.
authors.affiliation: Centre Hospitalier Universitaire de Laval Research Center, Laval University, Ste-Foy, Québec, Canada.
authors.forename: Marie Josée
authors.initials: MJ
authors.lastname: Fredette
authors.forename: Gaston
authors.initials: G
authors.lastname: De Serres
authors.forename: Mario
authors.initials: M
authors.lastname: Malenfant
mesh_terms: D000328:Adult; D003165:Complement System Proteins / Q000378:metabolism; D003231:Conjunctivitis / Q000209:etiology; D005128:Eye Diseases / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007114:Immunization; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D020795:Photophobia / Q000209:etiology; D012140:Respiratory Tract Diseases / Q000209:etiology*
chemical_list: D007252:Influenza Vaccines; D003165:Complement System Proteins