title: Prenatal diagnosis of capillary telangiectasia of the cerebellum--ultrasound and MRI features.
abstract: OBJECTIVE
  To report three cases of capillary telangiectasia (CT) of the cerebellum revealed as focal cerebellar lesions.
  
  
  METHODS
  Ultrasound and magnetic resonance imaging (MRI) were performed in all cases in the prenatal period. Prenatal imaging findings were compared with either post-mortem examination (case 1) or post-natal MRI (cases 2 & 3).
  
  
  RESULTS
  A discrepancy between a hyperechoic lesion without any mass effect on sonogram and normal T1 and T2 spin-echo fetal magnetic resonance images was found in all cases. The diagnosis of CT was made on post-mortem examination in case 1. Prenatal ultrasound and magnetic resonance imaging findings were suggestive of the diagnosis in cases 2 and 3. In both cases, the pregnancy was managed conservatively and the diagnosis of CT was documented on post-natal MRI after gadolinium injection.
  
  
  CONCLUSIONS
  The diagnosis of CT of the cerebellum was strongly suggested in these three cases in the prenatal period by the combination of ultrasound and fetal MRI findings. In the vast majority of cases, CT has a benign clinical course and complication with haemorrhage appears to be exceedingly rare. This fact should be taken into account in the prenatal counselling.
authors.affiliation: Department of Pediatric and Fetal Imaging, Hôpital Debrousse, Lyon. laurent.guibaud@chu-lyon.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: Guibaud
authors.forename: Catherine
authors.initials: C
authors.lastname: Garel
authors.forename: Buenerd
authors.initials: B
authors.lastname: Annie
authors.forename: Gaucherand
authors.initials: G
authors.lastname: Pascal
authors.forename: Varlet
authors.initials: V
authors.lastname: François
authors.forename: Chantal
authors.initials: C
authors.lastname: Vavasseur
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Oury
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Pracros
mesh_terms: D000328:Adult; D020785:Central Nervous System Vascular Malformations / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D016216:Ultrasonography, Prenatal