Oligonucleotides incorporating N7-(2'-deoxy-beta-D-erythro-pentofuranosyl)isoguanine.
The H-phosphonate and the phosphoramidite of N7-2'-deoxyisoguanosine (2) were prepared and incorporated into oligonucleotide duplexes. Their base pairing properties were investigated and compared with those of the parent purine nucleosides.
Leonard
P
P
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Osnabrück, Germany.
Kröschel
R
R
Seela
F
F
D000241:Adenosine; D001483:Base Sequence; D006151:Guanosine / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry
D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides; D006151:Guanosine; C008184:isoguanosine; D000241:Adenosine