Effects of the administration of spiramycin and tiamulin on in vivo complex formation and hepatic cytochrome P4503A (CYP3A)-dependent monooxygenases in rabbits.
Cantiello
M
M
Dipartimento di Patologia Animale, Sezione di Farmacologia e Tossicologia, Università di Torino, Torino, Italy.
Zaghini
A
A
Nebbia
C
C
Carletti
M
M
Dacasto
M
M
Anfossi
P
P
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D051544:Cytochrome P-450 CYP3A; D004224:Diterpenes / Q000494:pharmacology*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D010089:Oxidoreductases, N-Demethylating / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D011817:Rabbits; D015572:Spiramycin / Q000494:pharmacology*
D004224:Diterpenes; D015572:Spiramycin; C014224:tiamulin; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating