title: Staphylococcal exanthematous disease in a newborn due to a virulent methicillin-resistant Staphylococcus aureus strain containing the TSST-1 gene in Europe: an alert for neonatologists.
abstract: We report a case of staphylococcal exanthematous disease in a newborn due to a toxic shock syndrome toxin 1- and SEC-producing methicillin-resistant Staphylococcus aureus strain and alert neonatologists to the probable emergence in France of the neonatal toxic shock syndrome-like exanthematous disease in newborns previously described in Japan. We advise neonatologists to pay careful attention to clinical parameters and to prescribe appropriate tests: platelet count, serum C-reactive protein concentration, and Vbeta2-positive T-cell counts.
authors.affiliation: Relais Régional d'Hygiène Hospitalière du Centre, Hôpital Trousseau, Tours, France. n.vandermee@chu-tours.fr
authors.forename: Nathalie
authors.initials: N
authors.lastname: van der Mee-Marquet
authors.forename: Gérard
authors.initials: G
authors.lastname: Lina
authors.forename: Roland
authors.initials: R
authors.lastname: Quentin
authors.forename: Hélène
authors.initials: H
authors.lastname: Yaouanc-Lapalle
authors.forename: Christine
authors.initials: C
authors.lastname: Fièvre
authors.forename: Naoto
authors.initials: N
authors.lastname: Takahashi
authors.forename: Jerome
authors.initials: J
authors.lastname: Etienne
mesh_terms: D001427:Bacterial Toxins; D004768:Enterotoxins / Q000235:genetics; D005060:Europe; D005076:Exanthema / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D016106:Methicillin Resistance; D009359:Neonatology; D016133:Polymerase Chain Reaction; D012772:Shock, Septic / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000472:pathogenicity*; D018089:Superantigens; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal