title: The safety, tolerability and effectiveness of generic antiretroviral drug regimens for HIV-infected patients in south India.
abstract: We investigated the safety, tolerability and effectiveness of locally produced generic highly active antiretroviral therapy (HAART) regimens with a chart review conducted at YRG CARE, a tertiary HIV referral centre in India. A total of 333 patients had been on Indian-manufactured generic HAART for at least 3 months. In this cohort, generic HAART was safe, well tolerated and effective at increasing CD4 T-lymphocyte counts in patients with advanced HIV, comparable to the experience with proprietary HAART.
authors.affiliation: YRG Centre for AIDS Research and Education, Chennai, India.
authors.forename: Nagalingeswaran
authors.initials: N
authors.lastname: Kumarasamy
authors.forename: Suniti
authors.initials: S
authors.lastname: Solomon
authors.forename: Sreekanth K
authors.initials: SK
authors.lastname: Chaguturu
authors.forename: Anish P
authors.initials: AP
authors.lastname: Mahajan
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Flanigan
authors.forename: P
authors.initials: P
authors.lastname: Balakrishnan
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Mayer
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D018791:CD4 Lymphocyte Count / Q000379:methods; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D019829:Nevirapine / Q000009:adverse effects; D028761:Withholding Treatment
chemical_list: D019380:Anti-HIV Agents; D019829:Nevirapine