[Prevalence of erosive esophagitis in patients with subtotal gastrectomy: case-control study].
OBJECTIVE
Enterogastric bile reflux has been implicated as a definite causative factor for the development of postoperative bile reflux gastritis. However, little is known about the role of bile reflux into the stomach in gastro-esophageal reflux disease in patients with subtotal gastrectomy. In this study, we tried to prove that the bile reflux gastritis does increase the development of erosive esophagitis in patients who underwent subtotal gastrectomy.


METHODS
From January 1997 to December 2001, 222 patients with previous subtotal gastrectomy were enrolled. We also reviewed the endoscopic findings in 1,633 age and sex-matched healthy controls who had visited our hospital for routine check-up without significant gastrointestinal symptoms.


RESULTS
The prevalence of erosive esophagitis is 5% (LA A 2.7%, LA B 2.3%) in gastrectomized patients and 4.9% (LA A 3.2%, LA B 1.7%, LA C 0.0%) in healthy controls. There was no significant difference in the prevalence and the degree of esophagitis between the two groups.


CONCLUSIONS
These results suggest that subtotal gastrectomy may not be a risk factor for developing the erosive reflux esophagitis.
Suk
Ki Tae
KT
Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju-si, Gangwon-do, Korea.
Kim
Hyun Soo
HS
Kim
Jung Min
JM
Choi
Yeun Jong
YJ
Baik
Soon Koo
SK
Lee
Dong Ki
DK
Kwon
Sang Ok
SO
Kim
Dae Sung
DS
Kim
Won Joong
WJ
D000368:Aged; D016022:Case-Control Studies; D004942:Esophagitis, Peptic / Q000209:etiology*; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors