Prospects for gene therapy in hearing loss.
Deafness is the most common form of sensory impairment in humans. Depending on the age of onset, hearing impairment can affect oral language acquisition, cognitive development and psychosocial development. Here, we cover the latest advances in gene therapy for alleviating or preventing hearing loss. This review is not meant to be comprehensive, but to highlight some of the most recent developments in the field. Several recent reviews have described potential therapeutic approaches.
Avraham
Karen B
KB
Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. karena@post.tau.ac.il
Raphael
Yehoash
Y
D016923:Cell Death / Q000502:physiology; D015316:Genetic Therapy / Q000639:trends*; D006198:Hair Cells, Auditory / Q000502:physiology; D034381:Hearing Loss / Q000628:therapy*; D006801:Humans