Pentacyclic triterpenoid and saponins from Gambeya boukokoensis.
Chemical studies of the EtOAc extract of Gambeya boukokoensis Aubr. et Pellegr. stem bark led to the isolation of eight compounds. Three of them were elucidated as new compounds and designated as: gamboukokoensein A, 1alpha,2alpha,3beta,19alpha,23-pentahydroxyurs-12-en-28-oic acid; gamboukokoenside A, 2beta,3beta,6beta,28-tetrahydroxyolean-12-en-23-oic acid 23-O-alpha-L-arabinopyranosyl ester and gamboukokoenside B, 6beta,28-dihydroxy-3-oxoolean-12-en-23-oic acid 23-O-alpha-L-arabinopyranosyl ester. The other five compounds were known and identified as myrianthic acid, protobassic acid, oleanolic acid, erythrodiol and chondrillasterol. Their structures were elucidated on the basis of one and two dimensional NMR spectroscopic techniques, FABMS, ESMS and chemical evidence.
Wandji
Jean
J
Department of Organic Chemistry, University of Yaounde-1, Faculty of Science, PO Box 812 Yaoundé, Cameroon. jeanwandji@yahoo.fr
Tillequin
François
F
Mulholland
Dulcie A
DA
Shirri
Jovita Chi
JC
Tsabang
Nole
N
Seguin
Elisabeth
E
Verite
Philippe
P
Libot
Francine
F
Fomum
Z T
ZT
D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D011083:Polycyclic Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification*; D029632:Sapotaceae / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
D011083:Polycyclic Compounds; D012503:Saponins; D014315:Triterpenes