title: Gilbert's syndrome as a predisposing factor for idiopathic cholelithiasis in children.
abstract: The frequency of the (TA)7/(TA)7 promoter genotype of UDP-glucuronosyltransferase gene (UGT1A1) was significantly higher (p<0.05) in a group of 30 children with cholelithiasis than in a control group of 40 healthy children, indicating that this genotype might be an underlying factor for gallstone initiation in otherwise healthy children.
authors.forename: Sofia
authors.initials: S
authors.lastname: Kitsiou-Tzeli
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Kanavakis
authors.forename: Maria
authors.initials: M
authors.lastname: Tzetis
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Kavazarakis
authors.forename: Angeliki
authors.initials: A
authors.lastname: Galla
authors.forename: Aspasia
authors.initials: A
authors.lastname: Tsezou
mesh_terms: D002648:Child; D002769:Cholelithiasis / Q000201:enzymology / Q000453:epidemiology / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000453:epidemiology* / Q000235:genetics*; D005838:Genotype; D005878:Gilbert Disease / Q000201:enzymology / Q000235:genetics*; D014453:Glucuronosyltransferase / Q000235:genetics*; D006801:Humans; D017720:Molecular Epidemiology; D013577:Syndrome; D000099148:UGT1A1 Enzyme
chemical_list: D014453:Glucuronosyltransferase; D000099148:UGT1A1 Enzyme