[New prospects for a method of biospecific chromatography].
The polyacrylamide hydrogels with covalently immobilized ovomucoid from the duck's egg white were synthesized by radical copolymerization. These hydrogels can defend the immobilized insulin against the action of proteolytic enzymes. Biospecific interaction of the polysaccharide component of ovomucoid with lectins leads to the targeting transport of the hydrogel particles onto the small intestine wall.
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Topchiev Institute of Petrochemical Synthesis, Leninsky prospekt 29, Moscow, 117912 Russia. ivaluev@ips.ac.ru
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D000180:Acrylic Resins; D000818:Animals; D002845:Chromatography / Q000379:methods*; D004372:Ducks; D020100:Hydrogels; D000099166:Polyacrylamides
D000180:Acrylic Resins; D020100:Hydrogels; D000099166:Polyacrylamides