title: [Effects of tengcha flavonoids on scavenging oxygen free radicals and inhibiting lipid-peroxidation].
abstract: OBJECTIVE
  To study the effects of Tengcha flavonoids (TCF) on scavenging oxygen free radicals and inhibiting lipid-peroxidation.
  
  
  METHODS
  The effects of TCF on scavenging superoxide anion radical induced by xanthine-xanthine oxidase, inhibiting lipid-peroxidation of heart, liver, brain tissue homogenate and mitochondria induced by Fe2+ -VitC, Fe2+ -H2O2, Fe-Cys were discussed by TBA spectrometric method.
  
  
  RESULTS
  TCF could significantly inhibit the superoxide anion radical, IC50 is 14.7 mg/L, and the lipid peroxidation of liver homogenate and mitochondria induced by auto-oxidation and induced-oxidation. The inhibition exhibited concentration-dependent manner.
  
  
  CONCLUSIONS
  It indicated that TCF could scavenge oxygen free radicals and was capable of prophylacticly antagonizing against the oxidative injury by superoxide anion.
authors.affiliation: Hunan College of Traditional Chinese Medicine, Changsha 410007.
authors.forename: Guixia
authors.initials: G
authors.lastname: He
authors.forename: Fanglu
authors.initials: F
authors.lastname: Du
authors.forename: Weili
authors.initials: W
authors.lastname: Yang
authors.forename: Gang
authors.initials: G
authors.lastname: Pei
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D032421:Ampelopsis / Q000737:chemistry*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology*; D005609:Free Radicals / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008933:Mitochondrial Swelling / Q000187:drug effects; D010100:Oxygen / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D016166:Free Radical Scavengers; D005609:Free Radicals; D010100:Oxygen