Assessment of doses to the offspring of the Techa River cohort due to intakes of radionuclides by the mother.
The Techa River was contaminated as a result of radioactive releases by the Mayak plutonium production facility in 1949-1956. The residents of riverside communities were exposed to internal irradiation from radionuclides ingested mainly with river water, and also to external gamma irradiation resulting from shoreline and flood-plain contamination. The most important role in population exposure was played by (89,90)Sr and 137Cs. The persons born after the onset of the contamination have been identified as the 'Techa River Offspring Cohort' (TROC). The TROC has the potential to provide direct data on health effects in progeny that resulted from exposure of a general population to chronic radiation. This report describes the results of the calculation of fetal doses due to intakes of radionuclides by their mothers. Particular attention has been given to fetal dose from 90Sr because this nuclide is the most significant in terms of population dose for the Techa River. The comparison of the fetal bone marrow doses evaluated using different approaches proposed in the literature has shown a large dispersal in dose values. The main cause of this is the difference in model assumptions simplifying some developmental aspects of fetal haematopoiesis and bone formation. This paper presents an analysis of these basic assumptions that could be useful for further improvements in fetal dosimetry.
Degteva
M O
MO
Urals Research Center for Radiation Medicine, Medgorodok, 454076, Chelyabinsk, Russia. marina@urcrm.chel.su
Tolstykh
E I
EI
Vorobiova
M I
MI
D001822:Body Burden; D001853:Bone Marrow / Q000196:embryology* / Q000378:metabolism*; D002588:Cesium Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics; D015331:Cohort Studies; D003198:Computer Simulation; D005260:Female; D005333:Fetus / Q000378:metabolism; D005618:Fresh Water / Q000032:analysis; D006801:Humans; D018811:Maternal Exposure; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D008954:Models, Biological; D011247:Pregnancy; D011829:Radiation Dosage; D011850:Radioactive Waste / Q000032:analysis; D011868:Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics*; D011874:Radiometry / Q000379:methods* / Q000592:standards; D012426:Russia; D013326:Strontium Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics; D014018:Tissue Distribution; D014875:Water Pollutants, Radioactive / Q000032:analysis / Q000493:pharmacokinetics*
D002588:Cesium Radioisotopes; D011850:Radioactive Waste; D011868:Radioisotopes; D013326:Strontium Radioisotopes; D014875:Water Pollutants, Radioactive