[Memory consolidation and posttraumatic stress disorder].
Extensive evidence from animal and human studies has shown that memory formation is enhanced by an endogenous modulatory system mediated by stress hormones and activation of the amygdala. This system is an evolutionarily adaptive method of enhancing important memories. Under emotional stress, this system is activated promoting the formation of vivid, long lasting traumatic memories, which are the hallmark of PTSD. The understanding of the mechanisms underlying memory modulation might lead to an improved ability to assess and treat PTSD.
Quevedo
João
J
Laboratório de Neurotoxicologia da Universidade do Extremo Sul Catarinense. Criciúma, SC, Brasil. quevedo1@terra.com.br
Feier
Gustavo
G
Agostinho
Fabiano R
FR
Martins
Márcio R
MR
Roesler
Rafael
R
D004644:Emotions; D006801:Humans; D008568:Memory; D013313:Stress Disorders, Post-Traumatic / Q000523:psychology*