title: [Selective neck dissection in the treatment of pN1/2 lymph node metastases in the neck].
abstract: BACKGROUND
  As yet there is no single reliable and accurate method for detection of neck lymph node metastases. Therapeutic approaches differ from one author to other. The aim of this paper was to establish the extent to which, with good control of primary process, we can control spreading of malignant disease by means of selective neck dissection.
  
  
  METHODS
  This retrospective study included 595 surgically treated patients in the period 1990-1998. There were 525 patients with malignant laryngeal tumors, and 70 patients with malignant hypopharyngeal tumors. Preoperative diagnostics of enlarged lymph nodes was based on palpation of the neck, without CT, US, NMR diagnostics. With all risky N0 patients, selective neck dissection was performed for presence of occult metastases. Intraoperative frozen section analysis was not performed. Adjuvant radiatitherapy was performed in all patients in whom presence of neck lymph node metastases was histologically proved.
  
  
  RESULTS
  Selective lateral neck dissection was performed in 389 (65.4%) patients. In 78 (20%) patients, lymph node metastases were pathohistologically detected. In 5 (6.4%) transitional cellular cancer was histologically diagnosed, and the remaining 73 (93.6%) presented with squamous cell cancer. Postoperative radiation therapy was applied in 54 patients (69.2%) while 24 (30.8%) were not irradiated. 5-year survival was achieved in 18 (23.1%), and 3-year survival was achieved in 15 (19.2%) patients. Out of 45 patients who lived less than tree year, 18 (40%) presented with metastatic relapse and fatal outcome. Relapse of neck metastases appeared in 12 (11.9%) on the side and in the zones of lymph nodes which were included in neck dissection. Recurrence of neck metastases appeared in 8.3% of patients who were not irradiated postoperatively and in 32.1% of cases irradiated postoperatively.
  
  
  CONCLUSIONS
  This study includes comparison of our results with results of literature data.
  
  
  CONCLUSIONS
  Neck lymph node metastases point to advanced malignant process of the third or forth stage of the disease when results are the worst and 5-year survival decreases with or without adjuvant radiotherapy.
authors.affiliation: Klinika za bolesti uva, grla i nosa, Klinicki centar Novi Sad. rajkojov@eunet.yu
authors.forename: Rajko
authors.initials: R
authors.lastname: Jović
authors.forename: Karol
authors.initials: K
authors.lastname: Canji
authors.forename: Slobodan
authors.initials: S
authors.lastname: Mitrović
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kljajić
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology*; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D037981:Neck Dissection; D012189:Retrospective Studies; D015996:Survival Rate