Can roxithromycin and betamethasone induce acute pancreatitis? A case report.
BACKGROUND
Acute pancreatitis has been reported in a few cases treated with macrolides or glucocorticoids.


METHODS
We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis. Other causes of the disease were ruled out. No re-occurrence of pancreatitis was observed in a 16 month follow-up.


CONCLUSIONS
Our case sheds new light on glucocorticoid pancreatotoxicity and confirms the role of macrolides as potential pancreatotoxic drugs.
Renkes
Pascal
P
Hôpital-Clinique Claude Bernard. Metz, France. p.trechot@chu-nancy.fr
Petitpain
Nadine
N
Cosserat
Françoise
F
Bangratz
Sébastien
S
Trechot
Philippe
P
D000208:Acute Disease; D001623:Betamethasone / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced*; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy; D015575:Roxithromycin / Q000009:adverse effects* / Q000627:therapeutic use
D015575:Roxithromycin; D001623:Betamethasone