Oxidation of guanine nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane.
Final oxidation products generated from guanosine and 2'-deoxyguanosine by reaction with dimethyldioxirane have been identified as 4-amidinocarbamoyl-5-hydroxyimidazoles.
Davies
R Jeremy H
RJ
School of Biology and Biochemistry, Queen's University, Belfast, Northern Ireland. j.davies@qub.ac.uk
Stevenson
Clarke
C
Kumar
Shiv
S
Lyle
Jason
J
Cosby
Lisa
L
Malone
John F
JF
Boyd
Derek R
DR
Sharma
Narain D
ND
Hunter
Ann P
AP
Stein
Bridget K
BK
D000578:Amidines; D003849:Deoxyguanosine / Q000737:chemistry*; D004852:Epoxy Compounds; D006151:Guanosine / Q000737:chemistry*; D007093:Imidazoles; D007202:Indicators and Reagents; D010084:Oxidation-Reduction
D000578:Amidines; D004852:Epoxy Compounds; D007093:Imidazoles; D007202:Indicators and Reagents; D006151:Guanosine; D003849:Deoxyguanosine; C064455:dimethyldioxirane