Antitumour activity of Bauhinia variegata on Dalton's ascitic lymphoma.
The antitumour activity of the ethanol extract of Bauhinia variegata (EBV) has been evaluated against Dalton's ascitic lymphoma (DAL) in Swiss albino mice. A significant enhancement of mean survival time of EBV-treated tumour bearing mice was found with respect to control group. EBV treatment was found to enhance peritoneal cell counts. After 14 days of inoculation, EBV is able to reverse the changes in the haemotological parameters, protein and PCV consequent to tumour inoculation.
Rajkapoor
B
B
Department of Pharmacology, Vinayaka Mission's College of Pharmacy, Yercaud Road, Salem 636 008, Tamil Nadu, India. rajkapoorb@yahoo.co.in
Jayakar
B
B
Murugesh
N
N
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D001201:Ascites / Q000473:pathology; D001202:Ascitic Fluid / Q000473:pathology; D036481:Bauhinia; D045744:Cell Line, Tumor; D008223:Lymphoma / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation; D010529:Peritoneal Cavity / Q000166:cytology; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D018547:Plant Stems
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts