Synthesis of (Z)-(1-fluoro-2-hydroxymethylcyclopropylmethyl)purines.
(Z)-(1-fluoro-2-hydroxymethylcyclopropylmethyl)purines were designed, synthesized and evaluated their antiviral activity against poliovirus, HSV, and HIV.
Park
Ju-Hyun
JH
College of Pharmacy, Sookmyung Women's University, Yongsangu, Seoul, Korea.
Lee
Young Rang
YR
Chun
Moon Woo
MW
Jeong
Lak Shin
LS
Lee
Chong-Kyo
CK
Kim
Hee-Doo
HD
D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D015195:Drug Design; D006678:HIV / Q000187:drug effects; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests; D011687:Purines / Q000138:chemical synthesis* / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects
D000998:Antiviral Agents; D007202:Indicators and Reagents; D011687:Purines