title: Tourette's syndrome following temporal lobectomy for seizure control.
abstract: Gilles de la Tourette's syndrome (TS) is a neurobehavioral disorder characterized by multiple motor and vocal tics, occurring longer than a year and causing marked distress along with social and occupational impairments in level of functioning. It can be accompanied by obsessive-compulsive behavior and attention deficit disorder. This report discusses the case of a young woman with a simple motor tic disorder and intractable seizures who, after right temporal lobectomy for medically intractable epilepsy, developed TS with complex motor and vocal tics, severe obsessive-compulsive disorder, and paranoia. This neurobehavioral complication has not to our knowledge been previously reported after epilepsy surgery.
authors.affiliation: Brigham Behavioral Neurology Group, Memory Disorders Unit, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA. zelchemali@partners.org
authors.forename: Zeina
authors.initials: Z
authors.lastname: Chemali
authors.forename: Edward
authors.initials: E
authors.lastname: Bromfield
mesh_terms: D001007:Anxiety / Q000209:etiology / Q000523:psychology; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D006801:Humans; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D009771:Obsessive-Compulsive Disorder / Q000209:etiology / Q000523:psychology; D011183:Postoperative Complications / Q000523:psychology*; D013702:Temporal Lobe / Q000601:surgery*; D020323:Tics / Q000523:psychology; D005879:Tourette Syndrome / Q000209:etiology* / Q000523:psychology