title: Social and psychosocial influences on inflammatory markers and vascular function in civil servants (the Whitehall II study).
abstract: Social position and psychosocial factors are associated with coronary disease, but the underlying pathophysiologic mechanisms remain unclear. In a sample of 283 nonsmokers, we found that social position was inversely associated with interleukin-6 and C-reactive protein and that participants with mild depression had impaired endothelial function.
authors.affiliation: International Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London, United Kingdom. h.hemingway@public-health.ucl.ac.uk
authors.forename: Harry
authors.initials: H
authors.lastname: Hemingway
authors.forename: Martin
authors.initials: M
authors.lastname: Shipley
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Mullen
authors.forename: Meena
authors.initials: M
authors.lastname: Kumari
authors.forename: Eric
authors.initials: E
authors.lastname: Brunner
authors.forename: Mia
authors.initials: M
authors.lastname: Taylor
authors.forename: Ann E
authors.initials: AE
authors.lastname: Donald
authors.forename: John E
authors.initials: JE
authors.lastname: Deanfield
authors.forename: Michael
authors.initials: M
authors.lastname: Marmot
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D001824:Body Constitution; D002097:C-Reactive Protein / Q000032:analysis*; D003327:Coronary Disease / Q000453:epidemiology* / Q000523:psychology; D003863:Depression / Q000150:complications; D004651:Employment; D005215:Fasting; D005260:Female; D006801:Humans; D007328:Insulin / Q000032:analysis; D015850:Interleukin-6 / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012923:Social Class; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000032:analysis; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D007328:Insulin; D015850:Interleukin-6; D014280:Triglycerides; D002097:C-Reactive Protein