title: Familial chronic lymphocytic leukemia.
abstract: Familial aggregation of chronic lymphocytic leukemia (CLL) has been observed more frequently than familial aggregation of any other type of oncohematologic disorder. The presence of cells with a CLL-like immunophenotype (CLL-like cells) was recently documented in 13.5% healthy first-degree relatives of CLL patients. We present a family with CLL in which 2 brothers, a sister and their mother were affected.
authors.forename: Jan
authors.initials: J
authors.lastname: Cerny
authors.forename: Alena
authors.initials: A
authors.lastname: Slavickova
authors.forename: Anna
authors.initials: A
authors.lastname: Krepelova
authors.forename: Marek
authors.initials: M
authors.lastname: Trneny
authors.forename: Josef
authors.initials: J
authors.lastname: Karban
authors.forename: Pavel
authors.initials: P
authors.lastname: Klener
mesh_terms: D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics*; D008297:Male; D008875:Middle Aged