[Helicobacter pylori infection in the remnant stomach after radical subtotal gastrectomy].
OBJECTIVE
It was reported that the prevalence of Helicobacter pylori (H. pylori) infection decreased after gastrectomy, but persistent H. pylori infection may cause residual gastritis or stump cancer. We studied the prevalence of H. pylori infection in patients who had undergone subtotal gastrectomy for the treatment of gastric cancer and the factors that influence H. pylori positivity in the remnant stomach.


METHODS
Ninety-eight patients who had undergone radical subtotal gastrectomy (RSG group) for the treatment of gastric cancer and eighty-four patients diagnosed as having gastric cancer (GC group) were enrolled. H. pylori status was diagnosed by rapid urease test, histological examination, and 13C-urea breath test. We evaluated whether there were differences in various clinical characteristics according to the H. pylori status in the remnant stomach.


RESULTS
The prevalences of H. pylori infection in RSG group and GC group were 55% and 69%, respectively. In RSG group, the prevalence of H. pylori was 76.9% in patients aged 49 or less, and it decreased with age. The prevalence of H. pylori within 3 years of gastrectomy was 59.5% and it decreased to 28.6% after 3 years of gastrectomy.


CONCLUSIONS
The positive rate of H. pylori in RSG group is lower than that in GC group and decreases with age and time interval after operation.
Kim
Eun Soo
ES
Department of Internal Medicine, Gachon Medical School, Namdong-gu, Incheon, Korea.
Park
Dong Kyun
DK
Hong
Soon Hong
SH
Chung
Moon Gi
MG
Kwon
Oh Sang
OS
Kim
Sun Suk
SS
Koo
Yang Seo
YS
Kim
You Kyoung
YK
Kang
Dong Hoon
DH
Choi
Duck Joo
DJ
Park
Hyun Chul
HC
Lee
Woon Gi
WG
Kim
Ju Hyun
JH
D000368:Aged; D005260:Female; D005743:Gastrectomy; D018530:Gastric Stump; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000601:surgery