[Formation of congenital defects during ocular development. I. Embryogenesis of the eye and developmental birth defects].
Formation of developmental congenital defects of organ of vision finds its direct basis in the course of eye embryogenesis. Author of this work presents on the base of the literature, the crucial stages of embryonal development of eyeball and its individual structures. At every stage of development, the critical moments are shown, when the disturbance of the developmental process may lead to the origination of different groups of congenital eye defects. The knowledge of the potential period of particular congenital eye defects formation, facilitates the identification of eventual teratogenic factors, that have acted during pregnancy. It enables, to state the activity of gradually discovered genes, that regulate the course of embryonal development of the eye.
Krawczyński
Maciej R
MR
Pracowni Poradnictwa Genetycznego w Chorobach Narzadu Wzroku Katedry i Zakładu Genetyki Medycznej Akademii Medycznej w Poznaniu.
D005123:Eye / Q000196:embryology; D005124:Eye Abnormalities / Q000196:embryology*; D005260:Female; D006801:Humans; D011247:Pregnancy