title: Autologous hematopoietic stem cell transplantation for mediastinal extramedullary plasmocytoma.
abstract: Extramedullary plasmocytoma (EMP) is a rare cell neoplasm most frequently localised in the upper respiratory tract. We report the case of a 43 year-old-man, with an unusual presentation of EMP developing in the mediastinum, two years after a diagnosis of solitary plasmocytoma of the bone which was successfully treated by local irradiation. In this aggressive presentation, we decided to perform an autologous hematopoietic stem cell transplantation. Two months after transplantation, CT scan showed disappearance of the mediastinal mass and immunofixation of the serum was normal. Selected cases of diffuse EMP, could benefit from intensive treatment followed by autologous hematopoietic stem cell transplantation.
authors.affiliation: Centre National de Greffe de Moelle Osseuse, Tunis.
authors.forename: Abderrahmene
authors.initials: A
authors.lastname: Abdelkefi
authors.forename: Tarek
authors.initials: T
authors.lastname: Ben Othman
authors.forename: Lamia
authors.initials: L
authors.lastname: Torjman
authors.forename: Saloua
authors.initials: S
authors.lastname: Ladeb
authors.forename: Imed
authors.initials: I
authors.lastname: Ben Ghorbel
authors.forename: Amed
authors.initials: A
authors.lastname: Lakhal
authors.forename: Ramzi
authors.initials: R
authors.lastname: Ben Amor
authors.forename: Mohamed
authors.initials: M
authors.lastname: Miled
authors.forename: Mohamed-Nidhameddine
authors.initials: MN
authors.lastname: Kchir
authors.forename: Abdeladhim
authors.initials: A
authors.lastname: Ben Abdeladhim
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000628:therapy*; D005500:Follow-Up Studies; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000628:therapy*; D010954:Plasmacytoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D012272:Ribs; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous