Histoplasma granuloma of the conjunctiva.
OBJECTIVE
To describe the clinical and pathologic features of a conjunctival granuloma resulting from Histoplasma capsulatum.


METHODS
Clinicopathologic case report.


METHODS
Surgical excision of conjunctival lesion, histopathologic study with special stains, and a fluorescent antibody technique.


RESULTS
A conjunctiva granuloma was found to contain microorganisms, compatible with H. capsulatum, confirmed by a fluorescent antibody technique. The conjunctiva returned to normal.


CONCLUSIONS
A focal granuloma of the conjunctiva contained H. capsulatum in a patient whose recent symptoms suggested primary infection. The conjunctival lesion was similar to mucocutaneous lesions seen in patients with systemic histoplasmosis.
Knox
David L
DL
Eye Pathology Laboratory, Wilmer Institute and Department of Pathology, Johns Hopkins Medical Institution, 600 North Wolfe Street, Baltimore, MD 21287-9248, USA.
O'Brien
Terrence P
TP
Green
W Richard
WR
D000368:Aged; D003229:Conjunctival Diseases / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D015821:Eye Infections, Fungal / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D006801:Humans