title: Genetic diversity of serum proteins in three subpopulations of the Maria Gond tribe of Madhya Pradesh, India.
abstract: The phenotype and allele frequency distribution of group specific component (GC), transferrin (TF), alpha-1-antitrypsin (PI) and apolipoprotein E (APOE) was determined by isoelectric focusing of plasma samples from three subpopulations (Bison Horn Maria of the Kuakonda and Tokapal Block, and Abuj Maria of the Abujmar Hills of the Orchha block) of the Maria Gond tribe of Madhya Pradesh, India. A considerable level of allele frequency variation was observed in these subpopulations, which highlighted social and geographical isolation among them. The average heterozygosity for these IEF subtype systems was high (29-39%) and the gene diversity among these subpopulation groups was of low to moderate range (1.4%). The overall analysis showed that these polymorphisms are useful anthropological markers for micro-evolutionary and genetic structure studies.
authors.affiliation: Anthropology and Human Genetics Unit, Indian Statistical Institute, Kolkata, India.
authors.forename: K
authors.initials: K
authors.lastname: Das
authors.forename: M K
authors.initials: MK
authors.lastname: Das
authors.forename: S S
authors.initials: SS
authors.lastname: Mastana
mesh_terms: D001057:Apolipoproteins E / Q000032:analysis / Q000235:genetics; D001798:Blood Proteins / Q000032:analysis* / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population; D005843:Geography / Q000379:methods*; D006801:Humans; D007194:India / Q000208:ethnology; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D012934:Social Isolation; D014168:Transferrin / Q000032:analysis / Q000235:genetics; D014809:Vitamin D-Binding Protein / Q000032:analysis / Q000235:genetics; D000515:alpha 1-Antitrypsin / Q000032:analysis / Q000235:genetics
chemical_list: D001057:Apolipoproteins E; D001798:Blood Proteins; D014168:Transferrin; D014809:Vitamin D-Binding Protein; D000515:alpha 1-Antitrypsin