title: New adhesion prevention concept in gynecological surgery.
abstract: Postsurgical adhesion formation is a common but significant problem. This is the first clinical evaluation of a new barrier material designed to reduce or eliminate postsurgical adhesions. SprayGel can be delivered laparoscopically or via laparotomy to form a strongly adherent hydrogel film. In this multicenter study, we evaluated the safety and effectiveness of SprayGel absorbable adhesion barrier system in patients undergoing open or laparoscopic myomectomy procedures. Here, we discuss the results of our evaluation conducted at the University of Kiel and Polyclinic of Bordeaux, and assess some of the features of this novel adjunct to prevent formation of postsurgical adhesions.
authors.affiliation: Department of Obstetrics and Gynecology, University of Kiel, Kiel, Germany. endo-office@email.uni-kiel.de
authors.forename: L
authors.initials: L
authors.lastname: Mettler
authors.forename: A
authors.initials: A
authors.lastname: Audebert
authors.forename: E
authors.initials: E
authors.lastname: Lehmann-Willenbrock
authors.forename: V R
authors.initials: VR
authors.lastname: Jacobs
authors.forename: K
authors.initials: K
authors.lastname: Schive
mesh_terms: D000269:Adhesives; D000328:Adult; D000336:Aerosols; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007889:Leiomyoma / Q000601:surgery*; D009215:Myometrium / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*; D000267:Tissue Adhesions / Q000517:prevention & control*; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000601:surgery*
chemical_list: D000269:Adhesives; D000336:Aerosols