Inflammatory myoblastic tumor of the uterus and interleukin-6.
We report a patient with inflammatory myoblastic tumor of the uterus with constitutional symptoms. Surgical excision was curative and brought a rapid normalization in the elevated serum level of interleukin-6. We revealed an overproduction of interleukin-6 by a detection of messenger RNA by use of reverse transcriptase-polymerase chain reaction and immunohistochemistry.
Azuno
Yoichi
Y
Department of Internal Medicine, Yamaguchi Rosai Hospital, Onoda City, Japan. azuno@ymg.urban.ne.jp
Yaga
Ken
K
Suehiro
Yasuko
Y
Ariyama
Shigemi
S
Oga
Atsunori
A
D005260:Female; D005334:Fever; D006104:Granuloma, Plasma Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation; D015850:Interleukin-6 / Q000032:analysis* / Q000097:blood; D008875:Middle Aged; D014591:Uterine Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D015431:Weight Loss
D015850:Interleukin-6