title: MELAS as an example of a mitochondrial disease.
abstract: MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) is a disease mainly due to a mutation at position 3243 (A --> G) in the leucine tRNA gene in mitochondrial DNA. Symptoms of the disorder are complex and the exact pathogenesis is not understood. A review of the literature on the subject is presented.
authors.affiliation: Department of Genetics, University of Warsaw, Warszawa, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Piechota
authors.forename: K
authors.initials: K
authors.lastname: Mroczek
authors.forename: E
authors.initials: E
authors.lastname: Bartnik