title: Dysphagia and advancing age: are manometric abnormalities more common in older patients?
abstract: The universal process of aging may result in physiologic deterioration. Dysphagia may be more common in older patients. The effect of aging on esophageal manometry is not well established. The aim of this study was to determine if esophageal motility studies and associated symptoms in older patients with dysphagia differ significantly from younger patients. Patients who were 65 years of age or older (N = 53) were compared with patients who were 18-45 years of age (N = 53). Presenting symptoms, manometric findings, and diagnoses were compared between the two groups. In the older group, there were 29 women (55%), in the younger group there were 35 women (66%). The mean age of the older group was 75 +/- 7 years, the mean age in the younger group was 34 +/- 7 years. All patients reported dysphagia to solids. No significant differences were found in the reporting of associated symptoms. There were no significant differences in average lower esophageal sphincter (LES) resting pressure, residual LES pressure, LES relaxation, or peristalsis between groups. Older patients were as likely to have a normal study as younger patients (18% vs 23%, P = NS) and were also as likely to have the diagnosis of achalasia (32% vs 34%, P = NS). In conclusion, older and younger patients referred for manometric study of dysphagia have similar manometric findings. Esophageal manometry can be helpful in determining abnormalities in motility in both older and younger patients.
authors.affiliation: Department of Gastroenterology, Lahey Clinic, Burlington, Massachusetts 01805, USA.
authors.forename: Kristen M
authors.initials: KM
authors.lastname: Robson
authors.forename: Michael E
authors.initials: ME
authors.lastname: Glick
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D003680:Deglutition Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged