Hand-me-downs. Transmitting anterior-posterior asymmetry from older to younger egg follicles.
In Drosophila, the initial asymmetries that determine the embryonic body axes are generated during oogenesis. A report in this issue of Developmental Cell shows that a developing follicle conveys its anterior-posterior asymmetry to the next younger follicle via a relay mechanism that involves the Notch/Delta and the JAK/STAT signaling pathways.
Godt
Dorothea
D
Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario M5S 3G5, Canada.
Tepass
Ulrich
U
D000818:Animals; D019521:Body Patterning; D004330:Drosophila / Q000196:embryology; D005260:Female; D006080:Ovarian Follicle / Q000166:cytology / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*