title: Synthesis of new chiral monodentate phosphite ligands and their use in catalytic asymmetric hydrogenation.
abstract: [reaction: see text] New monodentate phosphite ligands have been developed from axially chiral biphenols, which show excellent enantioselectivity in the Rh(I)-catalyzed hydrogenation of dimethyl itaconate. The new chiral ligand system is suitable to create libraries and possesses fine-tuning capability.
authors.affiliation: Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400, USA.
authors.forename: Zihao
authors.initials: Z
authors.lastname: Hua
authors.forename: Victor C
authors.initials: VC
authors.lastname: Vassar
authors.forename: Iwao
authors.initials: I
authors.lastname: Ojima
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D008024:Ligands; D008956:Models, Chemical; D015394:Molecular Structure; D017905:Phosphites / Q000138:chemical synthesis* / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D008024:Ligands; D017905:Phosphites; D012238:Rhodium