title: De novo aneurysm formation 6 and 22 months after initial presentation in two patients.
abstract: Two cases of angiographically and surgically documented de novo intracranial aneurysm formation are reported. The first patient, a 32-year-old woman, developed two new aneurysms within a 6-month period, and the second patient, a 27-year-old woman, developed two new aneurysms within a 22-month period. In both patients, the new aneurysms were symptomatic, causing stroke and subarachnoid hemorrhage, respectively. The development of aneurysms de novo over such a short period of time has important implications for periodic imaging in patients considered to be at high risk for intracranial aneurysm formation.
authors.affiliation: Division of Interventional Neuroradiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
authors.forename: Rick
authors.initials: R
authors.lastname: Obray
authors.forename: Richard
authors.initials: R
authors.lastname: Clatterbuck
authors.forename: Alessandro
authors.initials: A
authors.lastname: Olvi
authors.forename: Rafael
authors.initials: R
authors.lastname: Tamargo
authors.forename: Kieran J
authors.initials: KJ
authors.lastname: Murphy
authors.forename: Philippe
authors.initials: P
authors.lastname: Gailloud
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging