title: Recurrence of ANCA-positive glomerulonephritis immediately after renal transplantation.
abstract: Recurrence of crescentic necrotizing glomerulonephritis after renal transplantation is rare. Successful renal transplantation in patients with antineutrophil cytoplasmic autoantibody (ANCA) glomerulonephritis has been reported. The presence of ANCA at transplantation does not appear to increase the rate of relapse after kidney allografting. Therapy with cyclophosphamide and corticoids usually is effective. We report a case of recurrent perinuclear ANCA crescentic necrotizing glomerulonephritis immediately after renal transplantation that was treated successfully by cyclophosphamide, plasma exchange, and intravenous polyvalent immunoglobulin.
authors.affiliation: Nephrology and Pathology Department, Caen University Hospital, Caen, France. lobbedez-t@chu-caen.fr
authors.forename: Thierry
authors.initials: T
authors.lastname: Lobbedez
authors.forename: François
authors.initials: F
authors.lastname: Comoz
authors.forename: Eric
authors.initials: E
authors.lastname: Renaudineau
authors.forename: Myriam
authors.initials: M
authors.lastname: Pujo
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Ryckelynck
authors.forename: Bruno
authors.initials: B
authors.lastname: Hurault de Ligny
mesh_terms: D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000276:immunology* / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D012008:Recurrence
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide