Two prolines with a difference: contrasting stereoelectronic effects of 4R/S-aminoproline on triplex stability in collagen peptides [pro(X)-pro(Y)-Gly]n.
4R/S-Aminoprolines when present in the X-position of collagen peptide [pro(X)-pro(Y)-Gly]n exhibit pH- and stereochemistry-dependent effects on triplex stability.
Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune 411008, India.
M
M
Umashankara
I Ramesh
IR
Babu
Krishna N
KN
Ganesh
D000595:Amino Acid Sequence; D002942:Circular Dichroism; D003094:Collagen / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009842:Oligopeptides / Q000737:chemistry*; D010446:Peptide Fragments / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry*; D011489:Protein Denaturation; D017433:Protein Structure, Secondary; D013237:Stereoisomerism; D013696:Temperature
D009842:Oligopeptides; D010446:Peptide Fragments; C467925:aminoproline; D003094:Collagen; D011392:Proline