[A case of delirium after olanzapine intoxication].
We describe a case of delirium due to olanzapine overdose. After ingestion of 280 mg of olanzapine, a 19-year-old schizophrenic patient developed a delirium (ICD-10: F 05.0) with consciousness disturbance, disorientation in time, space, and situation, acoustic and visual hallucinations, and agitation. The symptoms lasted for approximately 36 h. Blood pressure, temperature, and heart frequency showed no disturbance. There were no abnormalities in ECG, EEG, or routine blood tests. Approximately 36 h after the intoxication, the patient recovered fully. Until now, there have been no reports of delirium from this cause.
Universitätsklinik für Psychiatrie und Psychotherapie, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle. bettina.steil@medizin.uni-halle.de
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D000328:Adult; D014150:Antipsychotic Agents / Q000506:poisoning* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000506:poisoning* / Q000627:therapeutic use; D003693:Delirium / Q000139:chemically induced* / Q000175:diagnosis* / Q000523:psychology; D062787:Drug Overdose; D005260:Female; D006801:Humans; D000077152:Olanzapine; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine