Weber-Christian disease presenting with ocular manifestations.
A Japanese patient with Weber-Christian disease (WCD) presenting with ocular symptoms is reported. Panniculitis in the retrobulbar fat was diagnosed according to the histological findings from biopsy specimens, and improved over a month under steroid administration. Only three patients showing ocular manifestations have previously been reported. Panniculitis was in the late stage and a medium dose of prednisolone was effective in this patient. A biopsy of the orbital fat was useful for diagnosis. However, it is important to recognise that the stage of inflammation varies according to the fat tissue involved by WCD.
Kochi Medical School, Kochi, Japan.
T
T
Yoshida
H
H
Ito
Y
Y
Matsubara
Y
Y
Kitamura
A
A
Sasaoka
T
T
Chijiwa
K
K
Hashimoto
T
T
Komatsu
T
T
Moriki
T
T
Itahara
D000368:Aged; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D015434:Panniculitis / Q000175:diagnosis*; D010201:Panniculitis, Nodular Nonsuppurative / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D011239:Prednisolone