More chemistry of the thaxtomin phytotoxins.
Chemical and biochemical studies indicated the possible involvement of N-acetyltryptophan and 4-nitrotryptophan as intermediates in biosynthesis of the thaxtomin phytotoxins. A search for other potential pathways indirectly resulted in the identification of three unusual thaxtomin analogues derived from the o-thaxtomin A isomer. Investigations to resolve the identity of a previously described thaxtomin A di-glucoside were not supportive of the proposed structure.
Agriculture and Agri-Food Canada, Potato Research Centre, PO Box 20280, Fredericton, New Brunswick, Canada E3B 4Z7. kingr@agr.gc.ca
Russell R
RR
King
C Harold
CH
Lawrence
Jean
J
Embleton
Larry A
LA
Calhoun
D001427:Bacterial Toxins / Q000737:chemistry* / Q000378:metabolism; D007211:Indoles / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010879:Piperazines / Q000737:chemistry* / Q000378:metabolism; D013302:Streptomyces / Q000378:metabolism; D014364:Tryptophan / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism
D001427:Bacterial Toxins; D007211:Indoles; D010879:Piperazines; C006392:N-acetyltryptophan; D014364:Tryptophan