Looking up: regional patterning in the fly eye.
The Drosophila compound eye includes a dorsal domain specialized for the detection of the plane of polarized light. Two new papers show that this domain is controlled by graded Wingless signals acting through the homeodomain transcription factor Homothorax.
D'Costa
Allison
A
Department of Cell Biology, Emory University School of Medicine, 615 Michael Street, Room 400, Atlanta, GA 30322, USA.
Moses
Kevin
K
D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000254:growth & development*; D018398:Homeodomain Proteins / Q000378:metabolism; D006801:Humans; D008027:Light; D009024:Morphogenesis; D017956:Photoreceptor Cells, Invertebrate / Q000033:anatomy & histology / Q000254:growth & development* / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D051155:Wnt1 Protein
D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D011518:Proto-Oncogene Proteins; D051155:Wnt1 Protein; C108704:hth protein, Drosophila; C074622:wg protein, Drosophila