Meiosis: when even two is a crowd.
Recent studies in Caenorhabditis elegans show that crossover interference, which usually limits the number of exchanges per meiotic bivalent to just 'one', requires the continuity of both homologs. One 'function' of crossover interference may be the prevention of crossover events that might not effectively hold homologs together.
van Veen
J Edward
JE
Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA.
Hawley
R Scott
RS
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000502:physiology; D002842:Chromatids / Q000502:physiology*; D003434:Crossing Over, Genetic / Q000502:physiology*; D008540:Meiosis / Q000502:physiology*