[Changes of endocrine hormones during -6 degrees head down bed rest in human].
OBJECTIVE
To investigate changes of endocrine hormones during 7 d head down bed rest (HDBR).


METHODS
Six healthy male volunteers served as the subjects and experienced 7 d -6 degrees HDBR. Urine was collected from 6:00-22:00 and from 22:00-6:00. Serum was collected 48 h before HDBR, 48 h and 120 h during HDBR. Then the endocrine indices in urine and serum were determined.


RESULTS
1) The levels of serum CORT and ALD increased at 48 h during HDBR, while serum T3, T4, TP, UN decreased but they all recovered to normal at 120 h during HDBR. 2) The level of urine CORT, ALD and NE reached its peak in 24-48 h, and then gradually decreased to normal level.


CONCLUSIONS
The endocrine indices in serum and urine changed in the early period but returned to normal level gradually with the proceeding of HDBR.
Institute of Space Medico-Engineering, Beijing, China.
Li-xin
LX
Liang
Zhen-xiu
ZX
Liu
Yu-min
YM
Wan
Tang-bin
TB
Yang
D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D000450:Aldosterone / Q000097:blood / Q000378:metabolism / Q000652:urine; D001510:Bed Rest; D003348:Cortisone / Q000097:blood / Q000378:metabolism / Q000652:urine; D004703:Endocrine System / Q000378:metabolism*; D018475:Head-Down Tilt; D006728:Hormones / Q000097:blood / Q000378:metabolism* / Q000652:urine; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000097:blood / Q000378:metabolism / Q000652:urine; D013997:Time Factors; D018474:Weightlessness Simulation
D006728:Hormones; D000450:Aldosterone; D003348:Cortisone; D009638:Norepinephrine