Antimicrobial compounds of fungi vectored by Clusia spp. (Clusiaceae) pollinating bees.
The production of antimicrobial compounds by fungi associated with Clusia spp. pollinating bees (Trigona sp., Trigonini) was investigated in order to approach natural mechanisms of microbial density control within nest environment. By using a bioassay-guided approach based on bioautography and minimal inhibitory concentration (MIC), known alpha,beta-dehydrocurvularin and curvularin were isolated from Curvularia eragrostidis (CCT 5634) and Curvularia pallescens (CCT 5654), and known cochlioquinone A and isocochlioquinone A were isolated from Drechslera dematioidea (CCT 5631).
Bicalho
Beatriz
B
Universidade Estadual de Campinas - UNICAMP, Instituto de Química, CP 6154, Campinas (SP) 13083-970, Brazil.
Gonçalves
Regina A C
RA
Zibordi
Ana Paula M
AP
Manfio
Gilson P
GP
Marsaioli
Anita J
AJ
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001516:Bees / Q000382:microbiology / Q000502:physiology*; D016227:Benzoquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031251:Clusia / Q000737:chemistry*; D005658:Fungi / Q000187:drug effects / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011058:Pollen / Q000502:physiology*
D000935:Antifungal Agents; D016227:Benzoquinones; D010936:Plant Extracts; C066134:cochlioquinone A