[Giant pathologic section in the study of optimal length of surgical resection for esophageal carcinoma].
OBJECTIVE
To study the optimal surgical resection length for esophageal carcinoma.


METHODS
Specimens of seventy patients with esophageal squamous cell carcinoma resected and collected in our hospital were made into pathologic giant sections. Direct intramural infiltration, multicentric carcinogenic lesion and leaping metastasis were observed in the large slice by microscope. The actual length during the operation was calculated by the ratio of shrinkage.


RESULTS
Direct intramural infiltration was found in 51 (72.9%) patients, 39 proximal and 36 distal to the tumor. The mean length of direct intramural infiltration was 0.9 +/- 0.8 cm (4.0 cm maximum) proximally and 0.5 +/- 0.3 cm (2.0 cm maximum) distally. Multicentric carcinogenic lesion was found in 11 (15.7%) patients, 5 proximally, 8 distally and 2 on both sides. Proximal to the tumor, the mean distance between the multicentric carcinogenic lesion and the main lesion plus the length of the multiple carcinogenic lesion was 3.2 +/- 1.5 cm (4.7 cm maximum). Distal to the tumor, it was 3.6 +/- 2.4 cm (9.1 cm maximum). Leaping metastasis was found in 9 (12.9%) patients, 7 proximally and 4 distally. The mean distance between the leaping metastasis and the main lesion plus the length of the leaping metastatic lesion was 1.9 +/- 0.6 cm (2.9 cm maximum) proximally and 1.4 +/- 1.0 cm (2.7 cm in maximum) distally.


CONCLUSIONS
The optimal surgical resection length for esophageal carcinoma should be at least 5 cm proximal to the tumor and total length on the distal side.
Ma
Guo-wei
GW
Cancer Center, Sun Yat-Sen University, Guangzhou 510060, China.
Rong
Tie-hua
TH
Wu
Qiu-liang
QL
Long
Hao
H
Fu
Jian-hua
JH
Lin
Peng
P
Huang
Zhi-fan
ZF
Zeng
Can-guang
CG
Li
Xiao-dong
XD
Zhang
Xu
X
Zhang
Lan-jun
LJ
Wang
Jun-ye
JY
Hu
Yi
Y
Deng
Bang-fa
BF
D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness