[Effect of extensiveness of testicular germinoma on the choice of a treatment regimen].
Complex examination and treatment were given to 282 patients with testicular germ cell cancer. Diagnosis was histologically verified in all cases. Metastases at different sites were identified in 136 (48.2%). Seminoma was treated with telegamma radiation from the ROCUS-M installation; cases of non-seminoma pathology received VAB-6 and BEP regimes. Germ cell cancer staging was facilitated by joint use of up-to-date diagnostic procedures. X-ray examination of organs of the chest was performed in all cases and sometimes supplemented with CT. Ultrasound, CT and MRI were chiefly used for diagnosis of pathologies of the abdominal cavity and retroperitoneal space. Prognosis and chemotherapy regimes were based on tumor stage assessment. After therapy, recurrence-free cases and those with total regression were released from hospital. Oncological follow-up included tumor marker monitoring and dynamic X-ray examination of the chest, abdominal cavity and retroperitioneal space. When metastasis regression was not complete, surgery was indicated, if technically feasible.
I.P. Pavlov State Medical University, St. Petersburg.
A I
AI
Gorelov
E O
EO
Bogdanova
B K
BK
Komiakova
D000008:Abdominal Neoplasms / Q000556:secondary / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D017024:Chemotherapy, Adjuvant; D018237:Germinoma / Q000097:blood / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012186:Retroperitoneal Neoplasms / Q000556:secondary / Q000628:therapy; D018239:Seminoma / Q000473:pathology / Q000628:therapy; D013736:Testicular Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000628:therapy*
D014408:Biomarkers, Tumor