New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.
The Dyson Perrins Laboratory and The Oxford Centre for Molecular Sciences, South Parks Road, Oxford OX1 3QY, United Kingdom.
Michael A
MA
McDonough
Christopher J
CJ
Schofield
D000458:Cyanobacteria / Q000378:metabolism*; D047630:Depsipeptides; D015195:Drug Design; D010196:Pancreatic Elastase / Q000737:chemistry; D010456:Peptides, Cyclic / Q000737:chemistry / Q000494:pharmacology*; D012697:Serine Endopeptidases / Q000737:chemistry / Q000378:metabolism*; D015842:Serine Proteinase Inhibitors / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014357:Trypsin / Q000737:chemistry
C109608:A 90720A; D047630:Depsipeptides; D010456:Peptides, Cyclic; D015842:Serine Proteinase Inhibitors; C448645:scyptolin A; D012697:Serine Endopeptidases; D010196:Pancreatic Elastase; D014357:Trypsin