Cadmium-induced adaptive resistance and cross-resistance to zinc in Xanthomonas campestris.
Cadmium (Cd) and zinc (Zn) are environmental pollutants affecting both soil and water. The toxicity resulting from the exposure of Xanthomonas campestris, a soil bacterium and plant pathogen, to these metals was investigated. Pretreatment of X. campestris with sub-lethal concentrations of Cd induced adaptive protection against subsequent exposure to lethal doses of Cd. Moreover, Cd-induced cells also showed cross-resistance to lethal concentrations of Zn. These induced protections required newly synthesized proteins. Unexpectedly, Zn-induced cells did not exhibit adaptive protection against lethal concentrations of Zn or Cd. These data suggested that the increased resistance to Cd and Zn killing probably involved other protective mechanisms in addition to ion efflux.
Laboratory of Biotechnology, Chulabhorn Research Institute, Lak Si, Bangkok 10210, Thailand.
Peerakam
P
Banjerdkij
Paiboon
P
Vattanaviboon
Skorn
S
Mongkolsuk
D001426:Bacterial Proteins / Q000096:biosynthesis; D002104:Cadmium / Q000378:metabolism / Q000494:pharmacology*; D015169:Colony Count, Microbial; D024901:Drug Resistance, Multiple, Bacterial; D016959:Xanthomonas campestris / Q000187:drug effects* / Q000378:metabolism; D015032:Zinc / Q000378:metabolism / Q000494:pharmacology*
D001426:Bacterial Proteins; D002104:Cadmium; D015032:Zinc