Primary giant cell malignant fibrous histiocytoma of the kidney with staghorn calculi.
Malignant fibrous histiocytomas (MFH) as primary renal tumours are rare, with less than 50 cases described in the literature. We report a case of primary renal MFH of giant cell type in a 56-year-old man, who presented with bilateral dull flank pain, intermittent gross haematuria and body weight loss (6 kg in 3 months). Intravenous urography, computerized tomography (CT) and magnetic resonance image (MRI) showed right ureteral stones with mild hydronephrosis, and a solid mass at the lower pole of the left kidney associated with staghorn calculi, as well as tumour thrombi in the left renal vein and inferior vena cava. Left radical nephrectomy and evacuation of tumour thrombi from the left renal vein and inferior vena cava were performed. Histopathologic examination revealed malignant fibrous histiocytoma (MFH) of giant cell type. To the best of our knowledge, this is the first report of primary renal MFH associated with staghorn calculi.
Division of Urology, Department of Surgery, Department of Pathology, Chi Mei Medical Center, Tainan, Taiwan.
C H
CH
Chen
P S
PS
Lee
W J
WJ
Han
K H
KH
Shen
D005870:Giant Cell Tumors / Q000150:complications* / Q000175:diagnosis; D018219:Histiocytoma, Benign Fibrous / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007669:Kidney Calculi / Q000150:complications*; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged