Cell-death alternative model organisms: why and which?
Classical model organisms have helped greatly in our understanding of cell death but, at the same time, might have constrained it. The use of other, non-classical model organisms from all biological kingdoms could reveal undetected molecular pathways and better-defined morphological types of cell death. Here we discuss what is known and what might be learned from these alternative model systems.
Pierre Golstein, Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-l'Université de la Mediteranée, Parc Scientifique de Luminy, Case 906, 13288 Marseille cedex 9, France. golstein@ciml.univ-mrs.fr
Pierre
P
Golstein
Laurence
L
Aubry
Jean-Pierre
JP
Levraud
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D020169:Caspases / Q000378:metabolism; D004023:Dictyostelium / Q000502:physiology; D005658:Fungi / Q000502:physiology; D006801:Humans; D006829:Hydra / Q000502:physiology; D023421:Models, Animal; D010802:Phylogeny; D044446:Volvox / Q000502:physiology
D020169:Caspases