[Search for alternative secondary structures of RNA, regulating expression of bacterial genes].
Expression of many bacterial genes is regulated by formation of alternative secondary RNA structure within the leader mRNA sequence. Our algorithm designed to search for these structures (basing on analysis of one nucleotide sequence) was applied to analyze operons of amino acid biosynthesis in alpha- and gamma-proteobacteria. The attenuators of these operons are predicted for genomes of some poorly known gamma-proteobacteria including Shewanella putrefaciens, attenuators of the tryptophan operon in some alpha-proteobacteria are also predicted.
Liubetskaia
E V
EV
Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, 101447 Russia. lin@iitp.ru
Leont'ev
L A
LA
Gel'fand
M S
MS
Liubetskiĭ
V A
VA
D001483:Base Sequence; D015964:Gene Expression Regulation, Bacterial; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012329:RNA, Bacterial / Q000737:chemistry*; D012333:RNA, Messenger / Q000737:chemistry*; D012689:Sequence Homology, Nucleic Acid; D020614:Shewanella putrefaciens / Q000235:genetics
D012329:RNA, Bacterial; D012333:RNA, Messenger