[Reperfusion syndrome after direct myocardial revascularization on beating heart in patients with ischemic heart disease. Possibilities of prevention with amlodipine].
Possibilities of secondary prevention of reperfusion syndrome with amlodipine was assessed in 46 patients (39 with class III-IV angina after myocardial infarction and 7 with non ST elevation acute coronary syndrome). Twenty six patients received basic therapy, in 20 patients this therapy was supplemented with amlodipine (5-10 mg/day). In all patients complete direct arterial myocardial revascularization on beating heart was carried out. Methods of dynamic control included echocardiography, paired bicycle exercise tests, 6 minute walk test, myocardial scintigraphy with thallium-199. The results evidence for efficacy and feasibility of secondary prevention of reversible myocardial dysfunction with amlodipine.
Tepliakov
A T
AT
Research Insitute of Cardiology of the Research Centre of RAMS Siberian Branch, ul. Kievskaya 111, 634012 Tomsk, Russia.
Dzhavadova
G K
GK
Akhmedov
Sh D
ShD
Kandinskiĭ
M L
ML
Vesnina
Zh V
ZhV
D000328:Adult; D000368:Aged; D017311:Amlodipine / Q000008:administration & dosage / Q000627:therapeutic use*; D000787:Angina Pectoris / Q000601:surgery; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000601:surgery; D017202:Myocardial Ischemia / Q000601:surgery*; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D009204:Myocardial Revascularization; D011182:Postoperative Care; D011300:Preoperative Care; D011877:Radionuclide Imaging; D013577:Syndrome; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex
D002121:Calcium Channel Blockers; D017311:Amlodipine