[A case of lepromatous type Hansen's disease].
A 68 year-old male presented with painful swelling in the extremities and disseminated small brownish nodules over his entire body. A histological examination of the skin nodules showed multiple granuloma and a thickened peripheral nerve bundle surrounded with foamy macrophages and a few lymphocytes. Fite stain revealed numerous acid fast bacilli within the cytoplasm of the foamy cells. A diagnosis of lepromatous leprosy was thus made and multi-drug therapy following the Japanese guideline with DDS, rifampicin and clofazimine was started. The clinical features improved, and the morphological index decreased after undergoing chemotherapy. Although a severe type 1 reaction developed after four months of treatment, he was treated with oral prednisolone at a dose of 40 mg/day.
Kanazawa University Graduate School of Medical Science, Department of Dermatology, 15-1 Takara-machi, Kanazawa 920-8641, Japan. shirasah@med.kanazawa-u.ac.jp
Fumiaki
F
Shirasaki
Kazuhiko
K
Takehara
Minoru
M
Takata
Masako
M
Namisato
D000368:Aged; D004359:Drug Therapy, Combination; D006769:Hospitals, General; D006801:Humans; D007564:Japan; D007917:Leprostatic Agents / Q000008:administration & dosage*; D007918:Leprosy / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D016896:Treatment Outcome
D007917:Leprostatic Agents; D011239:Prednisolone