[Diagnostic conization of the uterine cervix and its effect on survival of patients after Wertheim-Meigs hysterectomy].
The aim of this retrospective work was to evaluate the diagnostic conization and its influence on morbidity and survival of patients with cervical cancer IB and IIA stage after radical hysterectomy a modo Wertheim-Meigs. The impact and influence of the irradical conization on the lymph node metastases and prognosis was analyzed. 535 patients in stage IB and IIA were examined for the period of 1990 and 2002. All of them were radically operated by Wertheim-Meigs method. There were 35 patients mainly from the countryside, who were treated by conization priory to radical hysterectomy. The time interval between the conization and the radical hysterectomies was between 5 and 8 weeks. The surgical morbidity and death incidence for patients with prior conization was not significantly different from other patients with directly radical hysterectomies. The survival was not significantly different between the two groups (84% vs 81%, p = 0.21). The Multivariate analysis which we used showed us that the irradical conization is not connected with higher risk of metastases or poor prognosis. We think that in early cervical cancer, the diagnostic conization has no adverse negative effect on the following radical hysterectomy a modo Werheim-Meigs. The irradical conization has no influence on prognosis.
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Ivanov
D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D019092:Conization / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000556:secondary / Q000601:surgery