Organocatalytic asymmetric Michael reaction of cyclic 1,3-dicarbonyl compounds and alpha,beta-unsaturated ketones--a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant.
Halland
Nis
N
The Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark.
Hansen
Tore
T
Jørgensen
Karl Anker
KA
D000925:Anticoagulants / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism; D014859:Warfarin / Q000138:chemical synthesis* / Q000737:chemistry
D000925:Anticoagulants; D007659:Ketones; D014859:Warfarin