Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model.
BACKGROUND
This study aimed to establish the accuracy and reproducibility of localization of intraluminal markers by laparoscopic and open techniques in a swine colorectal model, using a prototype for a novel wireless system.


METHODS
A prototype marker was placed into the colon of an adult pig. The surgeon was blinded to placement and localized the marker using a detection probe (3 surgeons/10 trials/2-D and 3-D systems).


RESULTS
Each surgeon was able to accurately locate the marker within 28.7 +/- 20.6 (LAP) and 18.3 +/- 6.7 (OPEN) sec ( p = 0.013). There were no significant differences between surgeons in localization times, regardless of experience. A 3-D interface made no difference in accuracy or time (LAP = 35 vs 28 seconds; p = NS [not significant]).


CONCLUSIONS
This study demonstrates the use of a novel system for intraoperative identification of nonpalpable lesions. This technology may have important implications in the surgical management of nonpalpable tumors and in applications of interventional radiology.
Department of Surgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
C J
CJ
Sonnenday
H S
HS
Kaufman
D000818:Animals; D003106:Colon / Q000601:surgery*; D012809:Colon, Sigmoid / Q000601:surgery; D015179:Colorectal Neoplasms / Q000601:surgery*; D004867:Equipment Design; D021621:Imaging, Three-Dimensional; D020007:Implants, Experimental; D007430:Intraoperative Care; D010535:Laparoscopy / Q000379:methods*; D008280:Magnetics; D023421:Models, Animal; D010865:Pilot Projects; D012007:Rectum / Q000601:surgery; D015203:Reproducibility of Results; D013552:Swine; D013997:Time Factors; D014584:User-Computer Interface