[Cyclosporin improved pure red cell aplasia associated with thymoma and tended to decrease thymoma size: a case report].
The case was a 56-year-old man who underwent extended thymothymectomy in 1993 because of an invasive thymoma classified as Masaoka IIa. The tumor was disseminated through the right thoracic cavity in 1994. Although the chemotherapy was repeated, the disseminated thymoma tended to increase in size. The patient was suffering from severe anemia, and pure red cell aplasia was diagnosed in September 2002. The administration of cyclosporin was initiated, and not only brought about improvement of pure red cell aplasia but also tended to shrink the thymoma. Cyclosporin may be an effective drug for the reduction of thymoma as well as for pure red cell aplasia.
Department of Respiratory Medicine, Tsuruoka City Shonai Hospital.
Hirofumi
H
Mochizuki
Tsuneto
T
Okada
Hirohisa
H
Yoshizawa
Eiichi
E
Suzuki
Fumitake
F
Gejyo
D003524:Cyclosporins / Q000008:administration & dosage*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012010:Red-Cell Aplasia, Pure / Q000150:complications / Q000188:drug therapy*; D013945:Thymoma / Q000150:complications / Q000188:drug therapy*; D013953:Thymus Neoplasms / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
D003524:Cyclosporins; D007166:Immunosuppressive Agents