Systemic lupus erythematosus-related acute pancreatitis: a case report.
Systemic lupus erythematosus presenting as acute pancreatitis is rare. We report a case of a 12-year-old girl with a 1-year history of systemic lupus erythematosus who developed active pancreatitis. The pancreatitis was first manifested by nausea, vomiting, fever, and abdominal pain. Elevated serum amylase (578 U/L) and lipase levels (5588 U/L), and pancreatic enlargement on ultrasound and computerized tomography confirmed the diagnosis. She responded well to high-dose corticosteroid. The high titer of antinuclear antibodies (1:1280) and low level of complement components (C3, 42.9 mg/dL; C4, 2.3 mg/dL) during the pancreatitis attack suggested that the pancreatitis may have been due to systemic lupus erythematosus exacerbation and not related to drug therapy.
Department of Pediatrics, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC.
Hueng-Chuen
HC
Fan
Shin-Nan
SN
Cheng
Yi-Ming
YM
Hua
Chia-Hsiang
CH
Chu
Chun-Jung
CJ
Juan
Ming-Yung
MY
Lee
Chih-Hsing
CH
Hung
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000681:Amylases / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D008049:Lipase / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D010179:Pancreas / Q000000981:diagnostic imaging; D010195:Pancreatitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D000305:Adrenal Cortex Hormones; D008049:Lipase; D000681:Amylases