HIV type 1 isolates from 200 untreated individuals in Ho Chi Minh City (Vietnam): ANRS 1257 Study.  Large predominance of CRF01_AE and presence of major resistance mutations to antiretroviral drugs.
HIV-1 isolates from 200 untreated patients recruited in 2001 and 2002 in the south part of Vietnam and particularly in Ho Chi Minh City were sequenced in the RT, protease, and env genes. Out of 200 isolates 198 belonged to CRF01_AE while only one subtype B and one intersubtype (B-CRF01_AE) recombinant could be observed. Of the isolates 6.5% had major resistance mutations to antiretroviral drugs.
Lan
Nguyen Thi Hoang
NT
Centre de Medecine Preventive, Ho Chi Minh Ville (HCMV), Viet Nam.
Recordon-Pinson
Patricia
P
Hung
Pham Van
PV
Uyen
Nguyen Thi Vy
NT
Lien
Truong Thi Xuan
TT
Tien
Huynh Tan
HT
Garrigue
Isabelle
I
Schrive
Marie-Hélène
MH
Pellegrin
Isabelle
I
Lafon
Marie-Edith
ME
Aboulker
Jean-Pierre
JP
Barré-Sinousi
Françoise
F
Fleury
Hervé J
HJ
D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000494:pharmacology* / Q000627:therapeutic use; D024921:Drug Resistance, Multiple, Viral; D005260:Female; D015752:Genes, env / Q000235:genetics; D015750:Genes, gag / Q000235:genetics; D015751:Genes, pol / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000737:chemistry / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D014744:Vietnam / Q000453:epidemiology
D019380:Anti-HIV Agents