A case study to demonstrate the role of proteases in wound healing.
Proteases play an important role in regulating the balance between tissue synthesis and degradation. However, in chronic wounds, this regulation may be defective and healing problems will result. This paper presents a case study detailing the use of a protease-modulating matrix (Promogran) on a chronic wound. First, the concept of wound healing is discussed.
Derbyshire
Adam
A
De Parys Medical Centre, Bedford Primary Care Trust.
D010450:Endopeptidases / Q000494:pharmacology*; D004827:Epilepsy / Q000150:complications; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy* / Q000201:enzymology* / Q000451:nursing; D008875:Middle Aged; D009779:Occlusive Dressings; D016896:Treatment Outcome; D014945:Wound Healing; D014947:Wounds and Injuries
D010450:Endopeptidases