Indium-catalyzed addition of active methylene compounds to 1-alkynes.
An active methylene compound adds to a 1-alkyne in high to quantitative yield upon heating in the presence of 0.05-5 mol % of In(OTf)3 to give an alpha-alkenylated carbonyl compound.
Department of Chemistry, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. masaharu@chem.s.u-tokyo.ac.jp
Masaharu
M
Nakamura
Kohei
K
Endo
Eiichi
E
Nakamura