Bioactive phenolics from Carthamus lanatus L.
Two flavonoid aglycons, eight flavonoid glycosides, chlorogenic acid and syringin were isolated from aerial parts of Carthamus lanatus. Isorhamnetin 3-O-beta-D-glucoside and chlorogenic acid were found for the first time in the genus Carthamus and respectively, quercimeritrin, astragalin, kaempferol 3-O-beta-D-sophoroside and syringin in the species. The ethyl acetate fraction of the methanol extract exhibited a higher antioxidant activity than the butanol fraction measured by the alpha,alpha-diphenyl-beta-picrazylhydrazyl (DPPH) free radical scavenging assay. Cytotoxicity and antioxidant activities of the main constituent, luteolin 7-O-beta-D-glucoside, were evaluated.
Taskova
Rilka
R
Institute of Botany, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Mitova
Maya
M
Mikhova
Bozhanka
B
Duddeck
Helmut
H
D000818:Animals; D001156:Artemia; D031178:Carthamus / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D008968:Molecular Conformation; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity*; D010946:Plants, Medicinal / Q000737:chemistry
D005419:Flavonoids; D010636:Phenols