Reconstruction for lower extremity limb salvage in soft tissue carcinoma.
Limb salvage procedures for the lower extremity have a 95% success rate and have essentially supplanted primary amputation as the primary treatment for limb-threatening malignancies. En bloc tumor resection involving major neural and vascular structures that once led to amputation are now successfully reconstructed using free-tissue transfer in combination with neoadjuvant and adjuvant chemoradiation therapies and brachytherapy. Planning for reconstruction of complex lower extremity wounds begins at the time of diagnosis and extends to postoperative rehabilitation. Developing a successful reconstructive plan requires a team approach with accurate assessment of the anticipated loss of critical structures, wound location, defect size, and an understanding of the local and distant tissues available for reconstruction. Comprehensive assessment of the anticipated wound combined with an understanding of the distant and local tissues available for reconstruction allows the reconstructive surgeon to select tissues from the entire body that have improved functional and aesthetic outcomes for patients.
Topham
Neal S
NS
Section of Plastic Surgery, Fox Chase Cancer Center, 333 Cottman Avenue, Suite C308, Philadelphia, PA 19111, USA. n_topham@fccc.edu
D003131:Combined Modality Therapy; D004632:Emergency Medical Services; D006801:Humans; D023821:Limb Salvage / Q000379:methods*; D035002:Lower Extremity / Q000601:surgery*; D011300:Preoperative Care; D012983:Soft Tissue Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D013524:Surgical Flaps / Q000145:classification