Model systems for flavoenzyme activity: flavin-functionalised SAMs as models for probing redox modulation through hydrogen bonding.
We report the fabrication of flavin-functionalised self-assembled monolayers upon gold electrodes and their subsequent redox modulation via hydrogen bonding to 2,6-diethylamidopyridine.
Cooke
Graeme
G
Centre for Biomimetic Design & Synthesis, Chemistry, William H. Perkin Building, School of Engineering & Physical Sciences, Heriot-Watt University, Riccarton, Edinburgh, UK EH14 4AS.
Duclairoir
Florence M A
FM
John
Phillip
P
Polwart
Neil
N
Rotello
Vincent M
VM
D000577:Amides / Q000737:chemistry; D004572:Electrolysis; D004800:Enzymes, Immobilized; D005415:Flavins / Q000737:chemistry*; D005420:Flavoproteins / Q000737:chemistry; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D015394:Molecular Structure; D009247:NADH, NADPH Oxidoreductases / Q000737:chemistry; D010084:Oxidation-Reduction; D011725:Pyridines / Q000737:chemistry
C487674:2,6-diethylamidopyridine; D000577:Amides; D004800:Enzymes, Immobilized; D005415:Flavins; D005420:Flavoproteins; D011725:Pyridines; D009247:NADH, NADPH Oxidoreductases