Bile anaerobic bacteria detection and antibiotic susceptibility in patients with gallstone.
OBJECTIVE
To detect bile anaerobic bacteria and antibiotic susceptibility in 59 patients with gallstones who had had cholecystectomy.


METHODS
BACT/ALERT 120 microbe detection system and SCEPTOR microbe detection system were used to detect bile anaerobic bacteria, antibiotic susceptibility.


RESULTS
The ratio of anaerobic bacteria to the patients examined was 52.5% (31/59). Obligate anaerobe bile culture showed positive results in 4 patients. B. fragilis (37.8%) was the major type of anaerobic bacteria in bile. Most (81.8%) of anaerobic bacteria were sensitive to metronidazole, and imipenem was suitable for beta-lactamase bacteria.


CONCLUSIONS
Culture of anaerobic bacteria in logarithmic phase can improve the positive rate of the culture. There are some relations between anaerobic infection and gallstone formation.
Lu
Yun
Y
The Department of Hepatobiliary Vascular Surgery, Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China. cloudylucn@yahoo.com
Xiang
Ting-Hai
TH
Shi
Jing-Sen
JS
Zhang
Bing-Yuan
BY
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000175:diagnosis*; D001646:Bile / Q000382:microbiology*; D005260:Female; D042882:Gallstones / Q000382:microbiology*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008828:Microbiological Techniques; D008875:Middle Aged
D000900:Anti-Bacterial Agents