Placidenes C-F, novel alpha-pyrone propionates from the Mediterranean sacoglossan Placida dendritica.
Four new alpha-pyrone-containing propionates (5-8) and an unprecedented hydroperoxide 9 have been isolated from the mantle extract of Placida dendritica, a Mediterranean sacoglossan that lives upon the green alga Bryopsis plumosa. The new metabolites co-occur with the related compounds 1-4, which have been described in previous studies of the mollusc. The presence of 9 opens intriguing perspectives on the ecological role of placidenes. This paper reports the isolation and structural elucidation of the new compounds 5-9.
Cutignano
Adele
A
Istituto di Chimica Biomolecolare del CNR, Via Campi Flegrei 34, 80078, Pozzuoli, Napoli, Italy.
Fontana
Angelo
A
Renzulli
Licia
L
Cimino
Guido
G
D000818:Animals; D000460:Chlorophyta; D002851:Chromatography, High Pressure Liquid; D008522:Mediterranean Sea; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D011422:Propionates / Q000737:chemistry / Q000302:isolation & purification*; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
D011422:Propionates; D011753:Pyrones