Elevated preoperative fasting serum glucose levels increase the risk of postoperative mediastinitis in patients undergoing open heart surgery.
We conducted a case-control study to investigate the relationship between preoperative fasting serum glucose and postoperative mediastinitis in patients undergoing open heart surgery. Multivariate analysis revealed that a glucose level of 126 mg/dL or greater was associated with a significantly increased risk of mediastinitis (OR, 5.25; P = .002).
Wilson
Stephen J
SJ
Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Sexton
Daniel J
DJ
D001786:Blood Glucose / Q000032:analysis*; D013504:Cardiovascular Surgical Procedures / Q000009:adverse effects*; D016022:Case-Control Studies; D005215:Fasting; D006801:Humans; D008480:Mediastinitis / Q000209:etiology*; D009657:North Carolina; D011183:Postoperative Complications; D011300:Preoperative Care; D012307:Risk Factors
D001786:Blood Glucose