The diagnosis and management of pre-invasive breast disease: the role of new diagnostic techniques.
In recent years we have seen significantly increased use of minimally invasive diagnostic techniques in the management of breast disease. There is wide recognition of fine needle aspiration and core biopsy as the principal diagnostic methods. However, concerns exist regarding their reliability. This article provides a brief overview of the major diagnostic issues related to use of fine needle aspiration, core biopsy and ductal lavage. It summarizes areas of use for each technique, outlines the main diagnostic pitfalls and their causes, and provides a perspective on future developments in the field.
Nerurkar
Ashutosh
A
Department of Histopathology, The Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK. Ashutosh.Nerurkar@rmh.nthames.nhs.uk
Osin
Peter
P
D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000737:chemistry / Q000473:pathology; D001941:Breast Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D003581:Cytodiagnosis / Q000379:methods; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D009361:Neoplasm Invasiveness; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity