Antimicrobial compounds of fungi vectored by Clusia spp. (Clusiaceae) pollinating bees.
The production of antimicrobial compounds by fungi associated with Clusia spp. pollinating bees (Trigona sp., Trigonini) was investigated in order to approach natural mechanisms of microbial density control within nest environment. By using a bioassay-guided approach based on bioautography and minimal inhibitory concentration (MIC), known alpha,beta-dehydrocurvularin and curvularin were isolated from Curvularia eragrostidis (CCT 5634) and Curvularia pallescens (CCT 5654), and known cochlioquinone A and isocochlioquinone A were isolated from Drechslera dematioidea (CCT 5631).
Universidade Estadual de Campinas - UNICAMP, Instituto de Química, CP 6154, Campinas (SP) 13083-970, Brazil.
Beatriz
B
Bicalho
Regina A C
RA
Gonçalves
Ana Paula M
AP
Zibordi
Gilson P
GP
Manfio
Anita J
AJ
Marsaioli
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001516:Bees / Q000382:microbiology / Q000502:physiology*; D016227:Benzoquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031251:Clusia / Q000737:chemistry*; D005658:Fungi / Q000187:drug effects / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011058:Pollen / Q000502:physiology*
D000935:Antifungal Agents; D016227:Benzoquinones; D010936:Plant Extracts; C066134:cochlioquinone A