Effect of dried fruits of Solanum nigrum LINN against CCl4-induced hepatic damage in rats.
Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity. The activity was evaluated using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and total bilirubin. The histopathological changes of liver sample in treated animals were compared with respect to control.
Raju
Kuppuswamy
K
PG & Research Department of Botany, Kandaswami Kandar's College, Namakkal, Tamil Nadu, India. raju_herbal@yahoo.com
Anbuganapathi
Govindaraju
G
Gokulakrishnan
Velusamy
V
Rajkapoor
Balasubramanian
B
Jayakar
Balasundarm
B
Manian
Sellamuthu
S
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism / Q000517:prevention & control*; D056486:Chemical and Drug Induced Liver Injury; D005638:Fruit; D008107:Liver Diseases / Q000378:metabolism / Q000517:prevention & control*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D032324:Solanum nigrum
D010936:Plant Extracts