[Correlative links between superoxide dismutase, catalase and glutathione peroxidase activities in mouse liver].
Qualitative and quantitative differences in correlative and regressive links between superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase were assessed in the mice liver by two- and three-dimensional statistical methods. Paired linear correlation analysis indicated SOD-CAT tandem as the correlatively acting enzymatic pair. Three-dimensional analysis revealed uniform response surfaces which exhibited higher activities at disproportional values of the other two and lower activities at proportional activities of the other two enzymes. The direct effect of the enzymes on each other was positive [table: see text] while the effect of their product was always negative.
Institute of Gerontology, Academy of Medical Sciences of Ukraine.
Kh K
KhK
Muradian
N A
NA
Utko
T G
TG
Mozzhukhina
I N
IN
Pishel'
A Ia
AIa
Litoshenko
V V
VV
Bezrukov
V E
VE
Fraĭfel'd
D000818:Animals; D002374:Catalase / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000378:metabolism*; D016014:Linear Models; D008099:Liver / Q000201:enzymology*; D051379:Mice; D008808:Mice, Inbred CBA; D013482:Superoxide Dismutase / Q000378:metabolism*
D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase