[Surgical treatment of thymomas in patients with generalized myasthenia gravis].
Experience in surgical treatment of 2977 patients with generalized myasthenia is presented, 386 (13%) of them have undergone surgeries for thymus tumors. Organo-specific tumors (thymoma) were diagnosed in 370 (95.9%) of them. Computed and magnetic-resonance tomography has the highest sensitivity and specificity in diagnosis of thymus tumors. Thymomthymectomy was performed in 317 patients including extended one in 117 (36.9%). Postoperative lethality in thymic tumor in the last years was 0.5%, general lethality over all period--5.1%. According to used classification (WHO, 1999) types of thymoma were the following: type A--2.1%, type B--86.3%, type AB--9.6%. Prognosis of surgical treatment depends of tumor type (it is worse in type B than in types A and AB), duration of the disease and severity of myasthenia.
Vetshev
P S
PS
Ippolitov
L I
LI
Merkulova
D M
DM
Zhivotov
V A
VA
Ponomarev
A B
AB
D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications*; D011379:Prognosis; D013934:Thymectomy; D013945:Thymoma / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D013950:Thymus Gland / Q000473:pathology; D013953:Thymus Neoplasms / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014944:World Health Organization