Anaesthetic management of the parturient with protein S deficiency and lumboperitoneal shunt.
Protein S, a vitamin K-dependent plasma protein, is a cofactor for protein C, an essential component of the regulatory system of coagulation. We describe the anesthetic management of a parturient with protein S deficiency and an indwelling lumboperitoneal shunt, which was placed following transverse and sagittal sinus thrombosis. She was treated with aspirin and enoxaparin during pregnancy and underwent caesarean section under general anaesthesia without complication.
Department of Anaesthesiology, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi, India.
Babita
B
Gupta
S
S
Prakash
K
K
Gujral
D000328:Adult; D000768:Anesthesia, General / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000627:therapeutic use; D018686:Anesthetics, Intravenous / Q000627:therapeutic use; D001279:Atracurium / Q000627:therapeutic use; D002557:Cerebrospinal Fluid Shunts; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000627:therapeutic use; D003473:Neuromuscular Nondepolarizing Agents / Q000627:therapeutic use; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D018455:Protein S Deficiency / Q000150:complications*; D013874:Thiopental / Q000627:therapeutic use
D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium; D007530:Isoflurane; D013874:Thiopental