Testing the nematophagous biological control strain Paecilomyces lilacinus 251 for paecilotoxin production.
Paecilomyces lilacinus is a nematophagous fungus currently developed as a biological control agent. In order to evaluate potential toxin production, culture extract and concentrated culture supernatant of P. lilacinus strain 251 were tested against Gram-negative and Gram-positive bacteria. High-performance liquid chromatography analysis was carried out to compare the chromatograms of P. lilacinus strain 251 with the chromatogram of known paecilotoxin. It was found that the 251 strain of P. lilacinus did not produce detectable levels of paecilotoxin or other toxins with antimicrobial activity.
Khan
Alamgir
A
Proteome Systems Ltd., 1/35-41 Waterloo Road, 2113, North Ryde, NSW, Australia. alamgir.khan@proteomesystems.com
Williams
Keith
K
Nevalainen
Helena
H
D000818:Animals; D000898:Antibiosis; D002851:Chromatography, High Pressure Liquid; D006090:Gram-Negative Bacteria; D006094:Gram-Positive Bacteria; D008826:Microbial Sensitivity Tests; D009183:Mycotoxins / Q000032:analysis / Q000096:biosynthesis*; D009348:Nematoda / Q000382:microbiology; D010143:Paecilomyces / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism* / Q000502:physiology; D014466:Ultraviolet Rays
D009183:Mycotoxins