Protein microarrays: promising tools for proteomic research.
Miniaturized and parallelized ligand binding assays are of great interest in postgenomic research because microarray technology allows the simultaneous determination of a large number of parameters from a minute amount of sample within a single experiment. Assay systems based on this technology are used for the identification and quantification of proteins as well as for the study of protein interactions. Protein affinity assays have been implemented that allow the analysis of interactions between proteins with other proteins, peptides, low molecular weight compounds, oligosaccharides or DNA. Microarray technology is an emerging technology used in global analytical approaches and has a considerable impact on proteomic research.
Templin
Markus F
MF
NMI Natural and Medical Sciences Institute, University of Tübingen, Markwiesenstrasse 55, D-72770 Reutlingen, Germany.
Stoll
Dieter
D
Schwenk
Jochen M
JM
Pötz
Oliver
O
Kramer
Stefan
S
Joos
Thomas O
TO
D000818:Animals; D000906:Antibodies / Q000737:chemistry* / Q000276:immunology; D002241:Carbohydrates / Q000737:chemistry*; D002460:Cell Line; D004268:DNA-Binding Proteins / Q000737:chemistry*; D006801:Humans; D007124:Immunoenzyme Techniques; D040081:Protein Array Analysis; D040901:Proteomics
D000906:Antibodies; D002241:Carbohydrates; D004268:DNA-Binding Proteins