Autochthonous Chagas' disease in Santa Catarina State, Brazil: report of the first case of digestive tract involvement.
We report the first case of digestive tract pathology (megaesophagus) determined by Trypanosoma cruzi infection in Santa Catarina State, southern Brazil. A 63-year-old female had presumptive clinical diagnosis of Chagas' disease, which was confirmed by imaging (endoscopy and esophagogram) and immunological methods. Further molecular diagnosis was carried out with esophagus and blood samples collected during corrective surgery. Polymerase chain reaction tested positive for Trypanosoma cruzi in both esophagus and buffy coat samples.
Departamento de Clínica Cirúrgica do Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Felipe Antonio Boff
FA
Maegawa
Ernesto Francisco
EF
Damerau
Ingrid Thais
IT
Beltrame-Botelho
Aldemar
A
Lopes
Priscilla
P
Emmanuelle-Machado
Mário
M
Steindel
Edmundo Carlos
EC
Grisard
D000818:Animals; D014355:Chagas Disease / Q000175:diagnosis*; D016054:DNA, Protozoan / Q000032:analysis; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000469:parasitology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014349:Trypanosoma cruzi
D016054:DNA, Protozoan