Lymphatic endothelium: morphological, molecular and functional properties.
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged. This overview highlights recent advances in our understanding of the molecular mechanisms underlying the formation and function of lymphatic vessels.
Department of Morphology, Unversity Medical Center, 1206, Genova, Switzerland.
Michael S
MS
Pepper
Mihaela
M
Skobe
D000818:Animals; D015415:Biomarkers; D004729:Endothelium, Lymphatic / Q000737:chemistry / Q000166:cytology* / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D045604:Extracellular Fluid / Q000378:metabolism; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008196:Lymph / Q000378:metabolism; D008207:Lymphatic Metastasis; D042601:Lymphatic Vessels / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D008954:Models, Biological; D011506:Proteins / Q000378:metabolism
D015415:Biomarkers; D011506:Proteins