The impact of exacerbations on the asthmatic patient's preference scores.
The purpose of this study was to examine the effect of exacerbations on mild to moderate asthmatic patients' preference-based, health-related, quality of life scores and also to describe the effect of these exacerbations on daily life. In a survey, 100 mild to moderate asthmatic patients in the United Kingdom were asked to rate three different health marker states on a scale between 0 (death) and 100 (perfect health), defined as: your asthma of today, a mild exacerbation, and a severe exacerbation of asthma. They were also asked to describe their symptoms and what they did when experiencing an exacerbation. During exacerbations the vast majority of asthmatic patients have significant symptoms and consume a considerable amount of health care resources, which often overlap. The health marker state "your asthma of today" was given a mean score of 81.0, a mild exacerbation a score of 62.1, and a severe exacerbation a score of 25.6, indicating a large impact on patients' daily life and their health-related quality of life. In conclusion, asthmatic patients are severely affected in their health and daily living by mild and severe exacerbations. Considerable effort should be made to reduce the number and severity of exacerbations.
Health Economics & Outcomes Research, AstraZeneca R&D, Lund, Sweden. fredrik.l.andersson@astrazeneca.com
Fredrik
F
Andersson
Sixten
S
Borg
Elisabeth
E
Ståhl
D000203:Activities of Daily Living; D001249:Asthma / Q000453:epidemiology / Q000523:psychology*; D001294:Attitude to Health; D005260:Female; D006295:Health Resources / Q000706:statistics & numerical data; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011788:Quality of Life; D012494:Sampling Studies; D011795:Surveys and Questionnaires; D013689:Telephone; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology