Disseminated cutaneous granulomatous eruption occurring in the setting of myelodysplasia.
A 66-year-old woman with a myelodysplastic syndrome developed a widespread, pruritic, nodular eruption. A skin-biopsy specimen showed a granulomatous infiltrate, with no evidence of clonality; a bone-marrow biopsy showed possible transition to acute myeloid leukemia. This presentation is consistent with two prior reports of granulomatous eruptions occurring in the setting of myelodysplasia.
Ronald O. Perelman Department of Dermatology, New York University, USA.
Kenneth A
KA
Katz
D000368:Aged; D002471:Cell Transformation, Neoplastic; D005260:Female; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000473:pathology; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology