Medical problems occurring during the long-term follow-up after liver transplantation.
Liver transplantation is a standardized therapy for end-stage liver disease. With current immunosuppressive protocols and patient care, ten-year patient survival rate has reached 60%. Several medical complications may develop during this period, including renal dysfunction, hypertension, diabetes mellitus, hyperlipidemia, and metabolic bone disease. The aim of this article is to analyze long-term results of several clinical trials reporting common medical dysfunctions after liver transplantation and to discuss their management.
Demirag
A
A
Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital, Geneva, Switzerland.
Bühler
L H
LH
Majno
P
P
Berney
Th
T
Chilcott
M
M
Giostra
E
E
Morel
Ph
P
Mentha
G
G
D002423:Cause of Death; D002986:Clinical Trials as Topic; D005500:Follow-Up Studies; D006801:Humans; D017093:Liver Failure / Q000401:mortality / Q000601:surgery*; D016031:Liver Transplantation / Q000401:mortality; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D016019:Survival Analysis; D017741:Survivors; D013557:Switzerland