Excision repair--its bacterial beginnings.
Nucleotide excision repair was first reported in 1964 by Setlow and Carrier and by Boyce and Howard-Flanders. These two reports clearly defined the existence in bacteria of a repair process that physically removed damaged sites, pyrimidine dimers, from the DNA in the form of acid-soluble fragments. These reports were the starting point for subsequent development of the whole field of DNA excision point.
Auerbaok Melanoma Laboratory, UCSF Cancer Center, Room N431, University of California, PO Box 0808, San Francisco, CA 94143-0808, USA. jcleaver@cc.ucsf.edu
James E
JE
Cleaver
D001419:Bacteria / Q000235:genetics*; D004260:DNA Repair; D005823:Genetics / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century