Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.
There is broad evidence that enteroviruses and adenoviruses can induce an acute inflammation of the myocardium without cardiac dysfunction (i.e. myocarditis) or with cardiac dysfunction (i.e. inflammatory cardiomyopathy) that can transform to a virus-negative dilated cardiomyopathy. In the adult patient neither other viruses (parvo-B 19 virus, hepatitis C virus, cytomegalovirus) nor post-infection autoimmunity are likely to induce idiopathic dilated cardiomyopathy.
Figulla
Hans R
HR
Medizinische Klinik III, Kardiologie, Angiologie, Internistische Intensivmedizin, Friedrich-Schiller-Universität Jena, Klinik für Innere Medizin I, Erlanger Allee 101, 07740 Jena, Germany. Hans.Figulla@med.uni-jena.de
D015551:Autoimmunity; D009202:Cardiomyopathies / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology* / Q000821:virology; D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D007249:Inflammation; D009205:Myocarditis / Q000276:immunology / Q000503:physiopathology* / Q000821:virology; D014777:Virus Diseases / Q000276:immunology / Q000503:physiopathology / Q000821:virology
D010450:Endopeptidases