[Assessment of the Gleason score in biopsies and specimens of radical prostatectomy].
OBJECTIVE
To evaluate the similarity between Gleason grade on prostate biopsies and their final result after radical prostatectomy.


METHODS
We retrospectively review the medical records of 129 patients who underwent radical prostatectomy. Mean PSA value was 10.7 ng/ml. The relationships between pathological reports of biopsies and radical prostatectomy specimens, and other variables such as PSA were established.


RESULTS
Globally, 72 cases (55.8%) were in the same risk group by grade on biopsy and surgical specimen. Biopsy result was understaged in 48 cases (37.2%) and overstaged in 9 cases (7%). We found biopsy understaging in 42 cases (60%) in the low grade group, 6 cases (10.9%) in the intermediate grade group, and 50% in the high grade group, although in this latter the number of cases was very low.


CONCLUSIONS
Overall biopsy understaging was 37.2%, being much more evident in low grade tumors (60%). It seems that understaging was greater when PSA > 10 ng/ml, although differences were not significant.
Servicio de Urología I, Hospital Central de Asturias, Oviedo, España.
Oscar
O
Rodríguez Faba
Jesús María
JM
Fernández Gómez
José Luis
JL
Guate Ortíz
José Luis
JL
Martín Benito
Francisco Javier
FJ
Pérez García
Jorge
J
García Rodríguez
Antonio
A
Jalón Monzón
Javier
J
Regadera Sejas
D001706:Biopsy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies