Drug interactions associated with HAART: focus on treatments for addiction and recreational drugs.
The advent of HAART has improved survival in patients infected with HIV; however, treatment is complicated by potential drug interactions. The risk of drug interactions is compounded by the use of additional therapies for comorbid conditions, such as substance abuse, and by the use of recreational drugs. HIV health care providers should be aware of the potential interaction of recreational drugs and addiction treatments with HAART because of the potential for significant adverse effects for their HIV-infected patients. This article provides a review of the literature on drug interactions among addiction therapies, recreational drugs, and HAART.
Albany College of Pharmacy, Alabany, NY, USA.
John J
JJ
Faragon
Peter J
PJ
Piliero
D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D004347:Drug Interactions; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects*; D008691:Methadone / Q000009:adverse effects*
D013287:Illicit Drugs; D008691:Methadone