Eurycomaoside: a new quassinoid-type glycoside from the roots of Eurycoma longifolia.
A new C(19)-quassinoid-type glycoside has been isolated from the roots of Eurycoma longifolia. The structure elucidation of the compound was achieved by a combination of one- and two-dimensional NMR techniques, including (1)H-(1)H-correlation spectroscopy (COSY), (1)H-(13)C-heteronuclear correlation spectroscopy (HMQC), and (1)H-(13)C-heteronuclear multiple-bond correlation spectroscopy (HMBC), as well as high resolution electrospray ionization Fourier transformation mass spectrometry (HR-ESI-FT-MS) data. The C(1)-glycosidation site in the quassinoid framework is encountered for the first time.
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, MS 38677, USA.
Erdal
E
Bedir
Hassan
H
Abou-Gazar
Julius Ngunde
JN
Ngwendson
Ikhlas Ahmad
IA
Khan
D002855:Chromatography, Thin Layer; D035701:Eurycoma / Q000737:chemistry*; D005583:Fourier Analysis; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D036702:Quassins / Q000138:chemical synthesis* / Q000737:chemistry* / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization
D006027:Glycosides; D010936:Plant Extracts; D036702:Quassins; C487302:eurycomaoside