Experimental animal models of muscle pain and analgesia.
Muscle pain is a prevalent clinical problem but can be difficult to treat because relatively little is known about nervous system mechanisms that mediate and modulate it. This review profiles four new animal models of muscle and deep tissue pain currently being used to elucidate mechanisms of muscle pain and analgesia.
Department of Anesthesiology and Pain Medicine, University of Minnesota, Minneapolis 55455, USA.
Lois J
LJ
Kehl
Carolyn A
CA
Fairbanks
D000137:Acid-Base Imbalance / Q000150:complications; D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D002351:Carrageenan; D004195:Disease Models, Animal; D006930:Hyperalgesia / Q000139:chemically induced / Q000503:physiopathology* / Q000628:therapy; D051379:Mice; D009068:Movement / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009369:Neoplasms / Q000150:complications; D010146:Pain / Q000209:etiology / Q000503:physiopathology*; D059408:Pain Management; D017288:Pain Threshold / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000009:adverse effects / Q000502:physiology; D051381:Rats
D002351:Carrageenan