A general synthetic route to 1-azabicyclo[m.n.0]alkenes via cyclisation based on alpha-sulfinyl carbanions.
The intramolecular nucleophilic addition of alpha-sulfinyl carbanions derived from the corresponding sufinyl lactams afforded 1-azabicyclo[m.n.0]alkenes in good yields.
Pohmakotr
Manat
M
Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand. scmpk@mahidol.ac.th
Numechai
Pornthep
P
Prateeptongkum
Saisuree
S
Tuchinda
Patoomratana
P
Reutrakul
Vichai
V