Mitosis: long-range signals guide microtubules.
The formation of microtubule-derived structures is thought to involve nucleation in all directions and stabilization of microtubules that contact relevant targets. A recent study indicates, during mitosis, there may be a third step, in which microtubule growth is directed over long distances without physical contact between the target and microtubules.
Department of Biochemistry and Molecular Genetics, University of Virginia Medical School, Charlottesville, Virginia 22908, USA. pts7h@virginia.edu
P Todd
PT
Stukenberg
D008870:Microtubules / Q000378:metabolism*; D008938:Mitosis / Q000502:physiology*; D015398:Signal Transduction; D008941:Spindle Apparatus / Q000502:physiology*