RED-T: utilizing the Ratios of Evolutionary Distances for determination of alternative phylogenetic events.
CONCLUSIONS
RED-T is a Java application for phylogenetic analysis based on a unique method, RED, that utilizes the ratios of evolutionary distances E(d) to distinguish between alternative evolutionary histories. RED-T allows the user to examine if any given experimental gene shares the same evolutionary history as the designated control gene(s). Moreover, the tool detects any differences in evolutionary history and allows the user to examine comparisons of E(d) for a likely explanation. Lateral gene transfer, which may have a significant influence in organismal evolution is one mechanism that could explain the findings of these RED-T analyses.


BACKGROUND
The application is available online at http://www.arches.uga.edu/~whitman/RED.
Department of Microbiology and Computer Science Department, The University of Georgia, Athens, GA 30602, USA.
Kamyar
K
Farahi
William B
WB
Whitman
Eileen T
ET
Kraemer
D005075:Biological Evolution; D002874:Chromosome Mapping / Q000379:methods*; D019143:Evolution, Molecular; D020869:Gene Expression Profiling / Q000379:methods*; D008040:Genetic Linkage / Q000235:genetics*; D019146:Hypermedia; D020407:Internet; D010802:Phylogeny; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid; D012984:Software; D014584:User-Computer Interface