Antioxidant flavonoids from the rhizomes of Helminthostachys zeylanica.
Eight flavonoids, ugonins E-L (1-8), were isolated from the rhizomes of Helminthostachys zeylanica, and their structures were established on the basis of spectral evidence. Compounds 3-8 were evaluated for their antioxidative activity in the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 6, 7 and 8 were more active than Trolox, with IC20 values of 5.29 +/- 0.32, 7.23 +/- 0.22, and 7.93 +/- 0.31, respectively.
Huang
Yu-Ling
YL
National Research Institute of Chinese Medicine, No. 155-1, Sec. 2, Li Nung St. Peitou, Taipei, Taiwan, Republic of China.
Yeh
Pei-Yu
PY
Shen
Chien-Chang
CC
Chen
Chien-Chih
CC
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001713:Biphenyl Compounds; D029624:Ferns / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000032:analysis; D027343:Rhizome / Q000737:chemistry*
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl