[Adhesion molecules: atherosclerosis and coronary artery disease].
Inflammation is now considered a critical pathogenic component of the atherosclerotic process. The initiation and progression of atherosclerosis as well as the pathogenesis of clinical forms of coronary artery disease are mediated by cell adhesion molecules. Their activation is associated with risk factors for atherosclerosis. The most important developments related to cell adhesion molecules and cardiovascular disease are the recognition of a novel target for therapeutics. Moreover the serum levels of adhesion molecules seem to be markers of the risk for cardiovascular events.
Katedra i Zakład Patofizjologii Slaskiej Akademii Medycznej, 40-752 Katowice, ul. Medyków 18. biboch@slam.katowice.pl
Katarzyna
K
Mizia-Stec
Barbara
B
Zahorska-Markiewicz
Leszek
L
Goliszek
D003324:Coronary Artery Disease / Q000378:metabolism*; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism*; D019010:Vascular Cell Adhesion Molecule-1 / Q000378:metabolism*
D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1