Heat stroke in familial dysautonomia.
A 14-month-old female with familial dysautonomia was referred to the pediatric department with high fever (41.6 degrees C), watery diarrhea, and vomiting. A few hours later, signs of encephalopathy appeared. Laboratory tests revealed elevated levels of lactate dehydrogenase (3500 U/L), aspartate aminotransferase (640 U/L), alanine aminotransferase (320 U/L), and creatine kinase (28,420 U/L). The diagnosis was heat stroke. Impaired autonomic nervous system function may be another risk factor for the development of heat stroke in young children.
Tirosh
Irit
I
Department of Pediatrics B, Schneider Children's Medical Center of Israel, Sackler Faculty of Medicine, Tel Aviv University, Petah Tiqva, Israel.
Hoffer
Vered
V
Finkelstein
Yaron
Y
Garty
Ben Zion
BZ
D001341:Autonomic Nervous System / Q000503:physiopathology; D003967:Diarrhea / Q000209:etiology; D004402:Dysautonomia, Familial / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005334:Fever / Q000209:etiology; D018883:Heat Stroke / Q000150:complications / Q000201:enzymology / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D014839:Vomiting / Q000209:etiology