Novel oxylipin metabolites from the brown alga Eisenia bicyclis.
Nine novel oxylipin metabolites together with several known ones were isolated from the brown alga Eisenia bicyclis. Five (1-5) of them are ecklonialactone derivatives containing a chlorine or an iodine atom, and two (6 and 7) are cymathere type oxylipins with a lactone ring or a chlorine atom. The structures of these oxylipin metabolites were confirmed by NMR and mass spectroscopy and compared with spectral data in the literature. The postulated biosynthetic pathway of these metabolites is discussed.
Department of Chemistry, College of Science & Engineering, Aoyama Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 229-8558, Japan.
Kenji
K
Kousaka
Nobuyuki
N
Ogi
Yasutomo
Y
Akazawa
Makiko
M
Fujieda
Yuzo
Y
Yamamoto
Yuuki
Y
Takada
Junji
J
Kimura
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D003517:Cyclopentanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D000459:Phaeophyceae / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
D000890:Anti-Infective Agents; D003517:Cyclopentanes; D005231:Fatty Acids, Unsaturated; D006574:Heterocyclic Compounds, 2-Ring