[Therapeutic efficiency of a combined use of low-intensity laser radiation and actovegin in gastroduodenal ulcers with inhibited cicatrix formation].
OBJECTIVE
To validate use of intravenous laser blood irradiation (ILBI) combined with actovegin administration in indolent gastroduodenal ulcers.


METHODS
Modern endoscopic, morphological, device, biochemical techniques and radioimmunoassay were used in examination of 92 patients with indolent gastroduodenal ulcers aged 24 to 69 years. ILBI plus actovegin was given in failure of standard medicinal therapy.


RESULTS
ILBI plus actovegin combination produced marked analgetic, anti-inflammatory and detoxication effects. Favourable trends were observed in the composition of gastric mucus, detoxication, reparative and metabolic processes in the gastroduodenal mucosa, neurohumoral regulation.


CONCLUSIONS
Combination of ILBI with actovegin proved highly effective in indolent gastroduodenal ulcers.
Ia M
IaM
Vakhrushev
E Iu
EIu
Shkatova
D000328:Adult; D000368:Aged; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001769:Blood / Q000528:radiation effects; D002921:Cicatrix; D003131:Combined Modality Therapy; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D005260:Female; D006418:Heme / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D028022:Low-Level Light Therapy; D008297:Male; D008875:Middle Aged; D013276:Stomach Ulcer / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects / Q000528:radiation effects
D000897:Anti-Ulcer Agents; D006418:Heme; C015646:Actovegin