Comparison of effect of glycoprotein IIb/IIIa inhibitors during percutaneous coronary interventions on risk of hemorrhagic stroke in patients >or=75 years of age versus those <75 years of age.
Of 1,369 consecutive patients who underwent stent-assisted coronary angioplasty and who were treated with glycoprotein IIb/IIIa inhibitors during these procedures, 17.5% were >or=75 years of age. Compared with patients <75 years old, those >or=75 years of age had similar procedural and in-hospital outcomes but significantly higher rates of hemorrhagic stroke (0.08% vs 1.2%, p <0.001).
Iakovou
Ioannis
I
Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA.
Dangas
George
G
Mehran
Roxana
R
Mintz
Gary S
GS
Lansky
Alexandra J
AJ
Aymong
Eve D
ED
Nikolsky
Eugenia
E
Vagaonescu
Tudor
T
Glasser
Lynne A
LA
Stone
Gregg W
GW
Leon
Martin B
MB
Moses
Jeffrey W
JW
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors* / Q000627:therapeutic use*; D012189:Retrospective Studies; D012306:Risk; D015607:Stents / Q000009:adverse effects; D020521:Stroke / Q000209:etiology / Q000517:prevention & control*
D019039:Platelet Glycoprotein GPIIb-IIIa Complex