The two main DNA lesions 8-Oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing properties.
Department of Chemistry, Philipps-Universität Marburg, Hans-Meerwein Strasse, 35 032 Marburg, Germany.
Matthias
M
Ober
Uwe
U
Linne
Johannes
J
Gierlich
Thomas
T
Carell
D020029:Base Pairing; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D009691:Nucleic Acid Denaturation; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010084:Oxidation-Reduction; D011743:Pyrimidines / Q000737:chemistry* / Q000378:metabolism; D013696:Temperature
D009943:Organophosphorus Compounds; D011743:Pyrimidines; C434331:phosphoramidite; C071023:2,6-diamino-4-hydroxy-5-formamidopyrimidine; C024829:8-hydroxyguanine; D006147:Guanine; D004247:DNA