Chromatid transport by pantographic motors (PMS).
The paper discusses a system of hinged leverages functioning as (vectorial) pantographic motors (PMs). Mediated by ratchets, PMs are suited for ferrying mammalian chromatids to mitotic antipoles. Several self-rectifying modes allow PMs to accurately partition genomes with minimal risk of engendering aneuploidy.
USC Medical School, Los Angeles, CA 90033, USA.
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Matioli
D000782:Aneuploidy; D000818:Animals; D001693:Biological Transport, Active; D002842:Chromatids / Q000378:metabolism* / Q000502:physiology*; D006801:Humans; D007477:Ions; D018386:Kinetochores / Q000378:metabolism; D008938:Mitosis; D008962:Models, Theoretical; D020409:Molecular Motor Proteins
D007477:Ions; D020409:Molecular Motor Proteins