Non-Hodgkin's lymphoma presenting with uterine and renal enlargement in a young girl.
Non-Hodgkin's lymphoma (NHL) is the fourth most common childhood malignancy. Uterine involvement with NHL is well described in adults, rare in children and has not been described in the first 2 years of life. While renal involvement in NHL is well recognised, diffuse renal enlargement is an uncommon finding. We report a unique case of B-cell lymphoma of primitive phenotype in a 15-month-old girl with uterine and renal involvement at presentation. We describe the US and MRI features at presentation that helped in the prospective diagnosis of this condition.
Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK. lfrost@doctors.org.uk
Lorraine D
LD
Moon
Clare
C
Brenner
Philip
P
Ancliff
Kieran
K
McHugh
Rose
R
DeBruyn
D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000601:surgery; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D013514:Surgical Procedures, Operative / Q000379:methods; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000601:surgery