[Influence of orthopnoea position on spirometric and plethysmographic parameters in patients with chronic obstructive pulmonary disease ].
Chronic obstructive pulmonary disease (COPD) is characterized by the lack or only slight reversibility of obstruction which can be assessed by spirometry after inhalation of short-acting beta 2-mimetic (e.g. Salbutamol). The aim of the study was to determine if subjective decrease in dyspnoea sensation notified by COPD patients in orthopnoea position is reflected in spirometry and plethysmography. The study was carried out in the group of 30 patients with COPD (FEV1 = 30-70% of predicted value) as well as in 30 sex- and age-matched non-smoking healthy subjects. We observed the increase of spirometric parameters (FEV1, FEV1%VC, FEF75, PEF) and the decrease of plethysmographic parameters (RTOT, RV, RV%TLC) after the change from the initial to orthopnoea position (p < 0.001). The obtained results show that orthopnoea position leads to the decline of obstruction degree, pulmonary hyperinflation and the decrease of dyspnoea sensation.
Krzyzowski
Grzegorz
G
Katedry i Kliniki Pneumonologii Slaskiej Akademii Medycznej w Centralnym Szpitalu Klinicznym w Katowicach.
Szulakowski
Patryk
P
Trzaska
Marzena
M
Pierzchała
Władysław
W
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage; D000368:Aged; D000420:Albuterol / Q000008:administration & dosage; D001993:Bronchodilator Agents / Q000008:administration & dosage; D016022:Case-Control Studies; D004417:Dyspnea / Q000209:etiology*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D010993:Plethysmography, Whole Body / Q000379:methods; D011237:Predictive Value of Tests; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000503:physiopathology*; D012123:Pulmonary Ventilation / Q000187:drug effects; D012119:Respiration; D013147:Spirometry / Q000379:methods; D016683:Supine Position; D013997:Time Factors
D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D000420:Albuterol