Increased myocardial uptake of iodine-123 metaiodobenzylguanidine on delayed images, compared with early images, in patients with multiple system atrophy.
We present 2 interesting cases of multiple system atrophy in which increased myocardial iodine-123 metaiodobenzylguanidine uptake was observed on delayed images (3 hours after injection) compared with early images (15 minutes after injection). These findings have not been previously described. The duration of symptoms was less than 1 year in both these patients. The mechanism responsible for these findings is not clearly understood, but could be related to the pathophysiological changes in the early stage of multiple systemic atrophy.
Department of Radiology, Matsusaka Central Hospital, Kawai-machi, Matsusaka, Mie, Japan. yasutaka@clin.medic.mie-u.ac.jp
Yasutaka
Y
Ichikawa
Kan
K
Takeda
Shuichi
S
Murashima
Hajime
H
Sakuma
Kaname
K
Matsumura
Tadanori
T
Hirano
Shigeki
S
Kuzuhara
D019797:3-Iodobenzylguanidine; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013997:Time Factors
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine