[Dynamics of parameters of variability of processes of repolarization after transluminal balloon angioplasty in patients with ischemic heart disease].
OBJECTIVE
To study dynamics of processes of repolarization after transluminal balloon angioplasty in patients with ischemic heart disease.


METHODS
ECG, Holter ECG monitoring, analysis of parameters of variability of processes of repolarization, echocardiography and treadmill stress echocardiography were carried out in 28 ischemic heart disease patients aged 51.3+/-8.1 years prior to percutaneous coronary intervention, before discharge and in 4.1+/-2.1 months after procedure. Coronary angiography was repeated after intervention when restenosis was suspected because of positive stress echo.


RESULTS
Number of vessels with significant stenoses was 1.8+/-0.1, number of implanted stents - 2.0+/-0.2. Analysis of parameters of variability of processes of repolarization at rest and after exercise revealed significant increases of maximal value of QT (MQT(c)) and of its dispersion (QT(cd)). In 3-5 days after procedure significant lowering of these parameters occurred. Development of restenosis during follow-up (in 6 patients, 21.4%) was associated with repeated increases of MQT(c) and QT(cd).


CONCLUSIONS
MQT(c) and QT(cd) are sensitive to myocardial ischemia and can be used as supplementary markers of myocardial ischemia during exercise tests in patients with ischemic heart disease.
A. N. Bakulev Research Center for Cardiovascular Surgery; Rublevskoye sh., 135, 121552 Moscow, Russia.
Iu I
IuI
Buziashvili
B G
BG
Alekian
R I
RI
Kabulova
E M
EM
Khananashvili
E U
EU
Asymbekova
I P
IP
Shuvaev
D A
DA
Dzhangdzhava
D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation / Q000502:physiology; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology* / Q000601:surgery*