1-[2-(2-hydroxyalkyl)phenyl]ethanone: a new photoremovable protecting group for carboxylic acids.
[reaction: see text] A new photoremovable protecting group for carboxylic acids is introduced. The protecting group 1-[2-(2-hydroxyalkyl)phenyl]ethanone, HAPE, is used to protect various carboxylic acids. When photolyzed, the protected compound releases the acid in 70-85% isolated yields. The synthesis and the results of photorelease of the protected acids are presented here.
Department of Chemistry, University of North Dakota, Grand Forks, North Dakota 58202-9024, USA.
Walters N
WN
Atemnkeng
Larry D
LD
Louisiana II
Promise K
PK
Yong
Breanne
B
Vottero
Anamitro
A
Banerjee