[A case-control study on the risk factors of leukemia in mining areas of rare-earth in South Jiangxi].
OBJECTIVE
In order to explore the correlation on radioactive contamination of lanthanon to leukemia, and provide clues for the causes and prevention of leukemia in mining areas of rare-earth elements.


METHODS
1:1 matched case-control study was used. A total of 51 clinically confirmed leukemia cases, individually matched with controls from general population, were interviewed in mining areas of rare-earth in South Jiangxi from November to December, 2001. Data were analyzed, using conditional logistic regression.


RESULTS
The main risk factors would include frequently drinking water from river (OR = 5.543), distance from residence to rare-earth mine and years for living in the area (OR = 3.308), exposure to organophosphorus pesticide (OR = 3.014). Tea drinking habit appeared to be a protective factor.


CONCLUSIONS
Leukemia seemed to be related to environmental pollution with rare-earth elements around the residential areas and organophosphorus pesticide exposure. The protective factor of tea drinking habit seemed to be unique in this study, which called for further studies.
Department of Epidemiology, Jiangxi Medical College, Nanchang 330006, China.
Lei
L
Wu
Yue-Ping
YP
Zhou
Hong-Jing
HJ
Zhong
D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007306:Insecticides / Q000633:toxicity; D007938:Leukemia / Q000209:etiology*; D016015:Logistic Models; D008297:Male; D008674:Metals, Rare Earth / Q000633:toxicity*; D008875:Middle Aged; D008906:Mining; D009943:Organophosphorus Compounds; D012307:Risk Factors; D013662:Tea; D014874:Water Pollutants, Chemical / Q000633:toxicity
D007306:Insecticides; D008674:Metals, Rare Earth; D009943:Organophosphorus Compounds; D013662:Tea; D014874:Water Pollutants, Chemical