Increasing prevalence of methicillin-resistant Staphylococcus aureus infection in California jails.
Staphylococcus aureus clinical isolates obtained from patients who were inmates of the San Francisco County jail system showed an increase in the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) from 29%, in 1997, to 74%, in 2002; 91% of the MRSA isolates carried staphylococcal chromosomal cassette mec (SCCmec) type IV. Pulsed field gel electrophoresis and multilocus sequence typing demonstrated 2 major clonal groups. One of these clonal groups is genetically indistinguishable from the strain responsible for an outbreak of MRSA in the Los Angeles County jail system in 2002.
Department of Pediatrics, San Francisco General Hospital, San Francisco, California 94110, USA. fpr@epi-center.ucsf.edu
Erica S
ES
Pan
Binh A
BA
Diep
Heather A
HA
Carleton
Edwin D
ED
Charlebois
George F
GF
Sensabaugh
Barbara L
BL
Haller
Françoise
F
Perdreau-Remington
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002140:California / Q000453:epidemiology; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008712:Methicillin / Q000494:pharmacology*; D016106:Methicillin Resistance / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D011330:Prisons; D013203:Staphylococcal Infections / Q000453:epidemiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D008712:Methicillin