The effect of profiling dialysate sodium and ultrafiltration on patient comfort and cardiovascular stability during haemodialysis.
The aim of this study was to investigate what affect profiling dialysate sodium and ultrafiltration rate had on cardiovascular stability during haemodialysis, and if there was any effect on patients' fluid balance, thirst, serum sodium levels, blood pressure, or comfort and tolerance. The past decade has seen major advances in haemodialysis machine technology. Parallel developments have included profiling dialysate sodium levels and fluid removal during dialysis. However, some dialysis centres do not use profiling due to fears of long-term detrimental effects, especially with regard to hypertension and fluid control. Within my own workplace, approximately 30% of haemodialysis treatments utilise either sodium or ultrafiltration profiling, or a combination of both. Anecdotally, we have seen an increase in cardiovascular stability and haemodialysis tolerance. The aim of this study was to identify the effects of profiling haemodialysis, to ensure that the treatment we offer patients is safe and effective.
Lincoln Renal Unit, University Hospitals of Leicester NHS Trust, Lincoln, UK.
M
M
Gerrish
J
J
Little
D000704:Analysis of Variance; D001294:Attitude to Health; D002319:Cardiovascular System / Q000187:drug effects* / Q000503:physiopathology; D018592:Cross-Over Studies; D015312:Hemodialysis Solutions / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007022:Hypotension / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D008991:Monitoring, Physiologic / Q000379:methods*; D010146:Pain / Q000209:etiology / Q000517:prevention & control; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods*; D012964:Sodium / Q000032:analysis / Q000097:blood / Q000494:pharmacology*; D011795:Surveys and Questionnaires; D013894:Thirst / Q000187:drug effects; D014883:Water-Electrolyte Imbalance / Q000209:etiology; D015430:Weight Gain / Q000187:drug effects
D015312:Hemodialysis Solutions; D012964:Sodium