Skin tension in the aetiology of Dupuytren's disease; a prospective trial.
Tension in the palmar fascia has been proposed as a factor causing Dupuytren's disease. If tension does stimulate the growth of new Dupuytren's tissue, relieving longitudinal tension should reduce the recurrence rate following surgery. Thirty patients with palmar Dupuytren's contracture of a single ray that affected only the metacarpophalangeal joint were divided into two groups. Both groups had a fasciotomy: one group through a transverse incision that was closed directly and the other through a longitudinal incision with Z-plasty closure. Half the patients (seven of 14) who had direct closure had recurrence at 2 years as compared to two of the 13 in the Z-plasty group. The trial was stopped at the interim analysis stage due to the high recurrence rate in the first group. These results are consistent with the tension hypothesis for the aetiology of Dupuytren's disease.
Nelson Hospital, Kingston Road, Wimbledon, London, UK. ncitron@4dudley.freeserve.co.uk
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Hearnden
D000368:Aged; D003286:Contracture / Q000209:etiology* / Q000601:surgery; D004387:Dupuytren Contracture / Q000209:etiology* / Q000601:surgery; D000071938:Fasciotomy; D005260:Female; D005500:Follow-Up Studies; D006227:Hand Deformities, Acquired / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008662:Metacarpophalangeal Joint / Q000601:surgery; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery; D012086:Reoperation; D012307:Risk Factors; D055502:Secondary Prevention; D013536:Suture Techniques