Does trauma trigger multiple sclerosis? 1: A controversy.
The potential role of trauma in the development of multiple sclerosis is important but controversial. Patients commonly ask about this and it has important medicolegal ramifications. In addressing such issues this article will consider both physical and psychological trauma, examine pathogenic mechanisms, and discuss the evidence for and against a relationship.
Weatherby
S J
SJ
Department of Clinical Neurology, City Hospital, Birmingham B18 7QH.
Hawkins
C P
CP
D001812:Blood-Brain Barrier / Q000502:physiology; D019317:Evidence-Based Medicine; D006801:Humans; D009103:Multiple Sclerosis / Q000209:etiology* / Q000523:psychology; D011446:Prospective Studies; D013315:Stress, Psychological / Q000150:complications*; D014947:Wounds and Injuries / Q000150:complications*