Role of lipopolysaccharide (LPS) in asthma and other pulmonary conditions.
Endotoxin significantly contaminates house dust and is an enhancing factor for asthma severity. Natural exposure to endotoxin in early life could influence immune development and protect from the risk of developing atopy. This article will focus on published data showing that home environmental contamination by endotoxin can participate in chronic airways diseases, in particular asthma.
Michel
Olivier
O
Clinic of Allergology and Respiratory Diseases, Saint-Pierre University Hospital, Free University of Brussels, Brussels, Belgium. omichel@ulb.ac.be
D000276:Adjuvants, Immunologic / Q000502:physiology*; D001249:Asthma / Q000276:immunology* / Q000503:physiopathology; D004391:Dust / Q000276:immunology*; D006801:Humans; D008070:Lipopolysaccharides / Q000276:immunology*
D000276:Adjuvants, Immunologic; D004391:Dust; D008070:Lipopolysaccharides