[Relationship between Chlamydia pneumoniae and classical risk factors of coronary heart disease].
In order to elucidate relationship between Chlamydia pneumonia infection and established risk factors of coronary heart disease (hypercholesterolemia, hyperglycemia, hyperfibrinogenemia, smoking, age) chlamydial IgA and IgG antibodies were determined by solid phase enzyme immunoassay in 122 patients with ischemic heart disease and 40 healthy subjects. Elevated titers of IgA class antibodies were found to be associated with presence of ischemic heart disease as well as with hypercholesterolemia, hyperglycemia, hyperfibrinogenemia, and smoking.
Khasaev
A Sh
ASh
Dagestan State Medical Academy, pl. V.I. Lenina 1, 367012 Makhachkala, Russia.
Gadzhieva
Z G
ZG
D000328:Adult; D000367:Age Factors; D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D023521:Chlamydophila Infections / Q000150:complications*; D016993:Chlamydophila pneumoniae / Q000276:immunology; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000209:etiology*; D003627:Data Interpretation, Statistical; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D005340:Fibrinogen; D002784:Cholesterol