[Loss of visual acuity due to choroidal ischemia in Fabry's disease].
We report a case of a 21-year-old man with Fabry's disease who presented with a sudden decrease in visual acuity to 20/200 in the left eye. Pale areas with a lobular choroidal distribution were seen on fundus examination. No retinal vascular causes were found on further evaluation. With anticoagulation treatment, the patient's subsequent course was good, with visual recovery to 20/25 and normalization of the funduscopic appearance. Recovery of both visual acuity and the pale, lobular areas suggested a choroidal etiology, probably ischemic because of the sudden onset. Choroidian ischemia is therefore a cause of visual acuity loss in Fabry's disease, so far not described in the literature.
Service d'ophtalmologie, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75679 Paris 14.
J-M
JM
Guenoun
C
C
Parc
D
D
Monnet
A-P
AP
Brezin
D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000795:Fabry Disease / Q000150:complications*; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000150:complications; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014792:Visual Acuity
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D010975:Platelet Aggregation Inhibitors