Cancer of the cervix with endometrial extension treated by radiotherapy: a retrospective case-control study.
BACKGROUND
Studies determining prognosis of cancer of the cervix with endometrial extension (CCEE) in a case-control fashion are scant.


METHODS
A case-control retrospective study of 20 women with CCEE and 16 patients with cervical cancer not extending to the endometrium (CCNEE) treated by radiation was undertaken. The patient groups were matched for age, disease stage, the presence of bulky/barrel-shaped tumor in the cervix, intercurrent illness, total radiation dose, and hemoglobin level. The overall mean follow-up was 54 months (range 8 to 218 months).


RESULTS
The numerical rates of local and systemic failure as well as 5-year survival were worse for patients with CCEE versus CCNEE. However, the observed differences were not statistically significant.


CONCLUSIONS
Involvement of the endometrium by cancer of the cervix seems to confer a worse outcome among cervical cancer patients treated by radiation alone.
Department of Radiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA.
F L
FL
Ampil
G
G
Caldito
J B
JB
Unger
D000328:Adult; D016022:Case-Control Studies; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy*