[Molecular mechanisms of stabilizing proteolytic enzymes. Model of a thermolysin-like microbial metalloproteinase].
The molecular mechanisms that ensure the stability of proteolytic proteins are discussed. The autolytic pathway of protease degradation is emphasized. Experiments aimed at increasing the thermal stability of thermolysin-like metalloproteases are comprehensively described.
Demidiuk
I V
IV
Institute of Molecular Genetics, Russian Academy of Sciences, pl. Kurchatova 2, Moscow, 123182 Russia.
Zabolotskaia
M V
MV
Safrina
D R
DR
Kostrov
S V
SV
D006868:Hydrolysis; D045726:Metalloproteases / Q000737:chemistry / Q000378:metabolism*; D013820:Thermolysin / Q000737:chemistry / Q000378:metabolism*
D045726:Metalloproteases; D013820:Thermolysin