Disposition of polyoxyethylated excipients in humans: implications for drug safety and formulation approaches.
Albert J
AJ
Ten Tije
Walter J
WJ
Loos
Jaap
J
Verweij
Sharyn D
SD
Baker
Kimberly
K
Dinh
William D
WD
Figg
Alex
A
Sparreboom
D019540:Area Under Curve; D002626:Chemistry, Pharmaceutical; D005079:Excipients / Q000009:adverse effects / Q000493:pharmacokinetics*; D006207:Half-Life; D006801:Humans; D011092:Polyethylene Glycols / Q000009:adverse effects / Q000493:pharmacokinetics*; D011136:Polysorbates / Q000009:adverse effects / Q000493:pharmacokinetics
D005079:Excipients; D011136:Polysorbates; C022131:cremophor; D011092:Polyethylene Glycols