CO2 laser in oral graft-versus-host disease: a pilot study.
This paper is the first to report the benefits of CO2 laser treatment for pain control in severe oral chronic graft-versus-host disease (GVHD). A CO2 laser device was used during 17 treatment sessions in four patients. The CO2 laser was applied over the mucosal lesions using 1 W for 2-3 s/1 mm(2). This treatment resulted in a consistent and significant decrease in pain, measured using a standard visual analogue scale. These results suggest that the CO2 laser can be used for the alleviation of pain in oral chronic GVHD.
Oral Medicine Department, The Hebrew University-Hadassah School of Dental Medicine, POB 12272, Jerusalem 91120, Israel. eladhome@md.huji.ac.il
S
S
Elad
R
R
Or
M Y
MY
Shapira
A
A
Haviv
D
D
Galili
A A
AA
Garfunkel
M
M
Bitan
E
E
Kaufman
D000293:Adolescent; D000328:Adult; D000368:Aged; D002245:Carbon Dioxide; D005260:Female; D006086:Graft vs Host Disease / Q000473:pathology / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009752:Nutritional Status; D010146:Pain / Q000209:etiology; D059408:Pain Management; D010865:Pilot Projects
D002245:Carbon Dioxide