Preventive measures in Peutz-Jeghers syndrome.
Peutz-Jeghers syndrome is a rare genetic disorder characterized by mucocutaneous melanin deposition, intestinal polyposis and an increased risk of cancer, both intestinal and extra-intestinal. We describe the current status of diagnosis and the methods by which the consequences of this condition can be minimized. A surveillance program for those diagnosed is also included.
Discipline of Surgical Science, Faculty of Health, University of Newcastle, NSW, Australia.
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DR
McGrath
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Spigelman
D003937:Diagnosis, Differential; D004724:Endoscopy; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D009369:Neoplasms / Q000209:etiology; D010375:Pedigree; D010580:Peutz-Jeghers Syndrome / Q000175:diagnosis / Q000473:pathology / Q000517:prevention & control*; D011379:Prognosis; D012307:Risk Factors