A Peutz-Jeghers syndrome case with iron deficiency anemia and jejuno-jejunal invagination.
Peutz-Jeghers syndrome is an autosomal dominantly inherited rare syndrome characterized by mucocutaneous pigmentations, with intestinal and extraintestinal polyps. It is accepted to be a precancerous syndrome. The polyps can cause anemia and intestinal obstruction and intussuception. We present a young patient admitted to our clinic with a history of recent gastrointestinal bleeding. Upper and lower gastrointestinal endoscopic examinations revealed multiple polyps located in the stomach, jejunum, rectum and terminal ileum. In addition, there were many mucocutaneous pigmentations on the lips, buccal mucosa and finger and toe nails. Jejunal polyps were found to be the cause of jejuno-jejunal invagination and iron deficiency anemia. Histopathological evaluation of the polyps revealed hamartomatous polyps of Peutz-Jeghers syndrome and this diagnosis was supported by a dermatology specialist. It is suggested that any patient presenting with ileus attacks and findings of anemia should be investigated for polyps and mucocutaneous pigmentations of the precancerous Peutz-Jeghers syndrome.
Sökmen
Haci Mehmet
HM
Gastroenterology Clinic, Haydarpasa Numune Education and Training Hospital, Istanbul, Turkey. alince@superonline.com
Ince
Ali Tüzün
AT
Bölükbaş
Cengiz
C
Kiliç
Güray
G
Dalay
Remzi
R
Kurdaş
Oya Ovünç
OO
D000293:Adolescent; D000714:Anastomosis, Surgical; D018798:Anemia, Iron-Deficiency / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001707:Biopsy, Needle; D003082:Colectomy / Q000379:methods; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007443:Intussusception / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D007579:Jejunal Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D010580:Peutz-Jeghers Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D018570:Risk Assessment; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler