The genetics of inflammatory bowel disease.
Over the past 10 years major progress has been made in understanding the genetic contribution to inflammatory bowel disease. NOD2 was recently identified as a major susceptibility gene for Crohn's disease. This and a number of other strong genetic leads are discussed.
Department of Gastroenterology, Addenbrooke's Hospital, Cambridge CB2 2QQ.
Bijay
B
Baburajan
Miles
M
Parkes
D002352:Carrier Proteins / Q000235:genetics; D025063:Chromosome Disorders / Q000235:genetics; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000235:genetics*; D047908:Intracellular Signaling Peptides and Proteins; D053473:Nod2 Signaling Adaptor Protein; D010375:Pedigree; D012307:Risk Factors; D018433:Twin Studies as Topic
D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein