Novel oxylipin metabolites from the brown alga Eisenia bicyclis.
Nine novel oxylipin metabolites together with several known ones were isolated from the brown alga Eisenia bicyclis. Five (1-5) of them are ecklonialactone derivatives containing a chlorine or an iodine atom, and two (6 and 7) are cymathere type oxylipins with a lactone ring or a chlorine atom. The structures of these oxylipin metabolites were confirmed by NMR and mass spectroscopy and compared with spectral data in the literature. The postulated biosynthetic pathway of these metabolites is discussed.
Kousaka
Kenji
K
Department of Chemistry, College of Science & Engineering, Aoyama Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 229-8558, Japan.
Ogi
Nobuyuki
N
Akazawa
Yasutomo
Y
Fujieda
Makiko
M
Yamamoto
Yuzo
Y
Takada
Yuuki
Y
Kimura
Junji
J
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D003517:Cyclopentanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D000459:Phaeophyceae / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
D000890:Anti-Infective Agents; D003517:Cyclopentanes; D005231:Fatty Acids, Unsaturated; D006574:Heterocyclic Compounds, 2-Ring