Segmental pedicle screw fixation or cross-links in multilevel lumbar constructs. a biomechanical analysis.
BACKGROUND
The placement of segmental pedicle screws and cross-links in short segment posterior pedicle screw constructs has been shown to increase the construct stiffness in some planes. To date, no studies have looked at the contributions of segmental pedicle screw and cross-link placement in longer constructs.


OBJECTIVE
To evaluate the influence of segmental pedicle screw and/or cross-link placement on flexion/extension, lateral bending and axial torsion stiffness in two- and three-level posterior pedicle screw fixation constructs.


METHODS
An in vitro biomechanical analysis of two- and three-level posterior pedicle screw constructs with and without segmental fixation and/or cross-links was performed using calf lumbar spines. Stiffness of the constructs was compared.


METHODS
Six calf lumbar specimens were used to test stiffness in one-, two- and three-level posterior pedicle screw fixation constructs in 12 configurations. A custom-made, four-axis spine simulator applied pure cyclical (+/-5 Nm) flexion/extension, lateral bending and axial torsion moments at 0.1 Hz under a constant 50-N axial compressive load. The stiffness of each construct was calculated about each axis of rotation. Data were analyzed using nonparametric techniques with statistical significance determined at alpha less than .05.


RESULTS
The stiffness of the instrumented spines were significantly greater than the noninstrumented intact spines in all loading conditions for one-, two- and three-level constructs. There were no significant changes in flexion/extension stiffness with the addition of either the cross-links or the segmental pedicle screws. In lateral bending, the addition of segmental pedicle screws significantly increased the stiffness in the two- and three-level constructs. The addition of two cross-links increased lateral bending stiffness in the longer three-level constructs, with little change in the two-level constructs. In axial torsion, the progressive addition of cross-links showed a tendency toward increased stiffness in both the two- and three-level constructs. Segmental pedicle screws further increased torsional stiffness of the longer, three-level constructs.


CONCLUSIONS
As the use of segmental spinal instrumentation progresses from one to two and three levels, the contribution of cross-links and segmental pedicle screws to the overall construct stiffness increases.
Brodke
D S
DS
Department of Orthopaedics, Orthopaedic Bioengineering Research Laboratory, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. darrel.brodke@hsc.utah.edu
Bachus
K N
KN
Mohr
R A
RA
Nguyen
B K
BK
D000818:Animals; D001696:Biomechanical Phenomena; D001863:Bone Screws; D002417:Cattle; D066298:In Vitro Techniques; D008159:Lumbar Vertebrae / Q000502:physiology* / Q000601:surgery*; D008422:Materials Testing; D014102:Torsion Abnormality