Embryonal rhabdomyosarcoma of the uterine cervix: case report and review of the literature.
OBJECTIVE
Sarcoma botryoides rarely arises in the uterine cervix. It usually presents in the adolescent age group. The peak incidence is in the second decade. A combined modality approach to treating rhabdomyosarcoma (RMS) has markedly improved survival. We present two cases of cervical RMS. One of them had a very aggressive clinical course.


METHODS
Two cases of RMS in young women who presented with rapidly progressive cervical tumor are reported. They were treated with two-stage surgical procedure and chemotherapy.


CONCLUSIONS
A combined modality approach to treating RMS using multidrug chemotherapy, radiotherapy, and surgery has markedly improved survival. One of our cases has been free of disease for more than 5 years.
Gynecology Oncology Department, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran 14194, Iran. valrec2@yahoo.com
Nadereh
N
Behtash
Azam
A
Mousavi
Afsaneh
A
Tehranian
Navid
N
Khanafshar
Parviz
P
Hanjani
D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D018233:Rhabdomyosarcoma, Embryonal / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*