Synthesis of glycosylcurcuminoids.
Condensation of glycosylated arylaldehyde with acetylacetone-B(2)O(3) complex gave a corresponding diglycosylcurcuminoid, and a similar reaction using a mixture of arylaldehyde and glycosylarylaldehyde gave an unsymmetrical monoglycosylcurcuminoid, both as boron-complexes. The boron was removed from the complexes by heating in methanol, thus achieving the synthesis of di- and mono-glycosylcurcuminoids.
Mohri
Kunihiko
K
Showa Pharmaceutical University, Tokyo, Japan. mohri@ac.shoyaku.ac.jp
Watanabe
Yuhya
Y
Yoshida
Yuki
Y
Satoh
Mitsuru
M
Isobe
Kimiaki
K
Sugimoto
Naoki
N
Tsuda
Yoshisuke
Y
D000447:Aldehydes / Q000737:chemistry; D001895:Boron / Q000737:chemistry; D030024:Curcuma / Q000737:chemistry; D003474:Curcumin / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D012997:Solvents; D013055:Spectrophotometry, Infrared
D000447:Aldehydes; D007202:Indicators and Reagents; D012997:Solvents; D003474:Curcumin; D001895:Boron; D000432:Methanol