[Analysis of cases of acute poisoning with cardiovascular drugs].
A retrospective analysis of cases of acute poisoning with cardiovascular drugs in the period from 1999 to 2002 has been carried out. A total of 72 poisoned patients was treated in the study period in the Lublin Regional Toxicological Centre. The poisoned were mostly women (69%), out of whom 76% were under 30. More than 66% were the cases of mixed poisoning, especially with antidepressant or sedative-hypnotic drugs. Alcohol poisoning was diagnosed in 28% of cases and it was statistically more frequent in men than in women (54.6% and 16.0%, respectively). Cardiovascular drugs were the most frequent cause of suicidal poisoning cases, i.e. beta-blockers were the cause of 40% poisoning cases, ACEI inhibitors--22%, and calcium channel blockers--19%. In 25 cases (in 18 women and 7 men) severe poisoning caused bradyarrhythmia or hypotonia which resulted in the death of 2 patients.
Regionalny Ośrodek Toksykologii Klinicznej Samodzielny Publiczny Szpital Wojewódzki im. Jana Bozego w Lublinie, 20-089 Lublin, ul. Biernackiego 9.
Leszek
L
Gnyp
Hanna
H
Lewandowska-Stanek
Jarosław
J
Sawiniec
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000453:epidemiology; D001919:Bradycardia / Q000139:chemically induced* / Q000453:epidemiology; D002316:Cardiotonic Agents / Q000506:poisoning*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D002316:Cardiotonic Agents