[Clinical and pathological features of 23 patients with primary lymphoma of the testis].
OBJECTIVE
To study the clinical and pathological features of primary lymphoma of the testis and try to find out the rational treatment modality.


METHODS
Retrospective and follow-up analysis was conducted in 23 patients with primary lymphoma of the testis. Survival analysis was performed by Kaplan-Meier process.


RESULTS
The primary clinical symptom was painless tumefaction. 78.3% lesions were Stage I(E) on diagnosis. Most of them were intermediate grade B cell lymphoma. All patients received orchiectomy followed by chemotherapy and some followed by radiotherapy. The median survival time was 42 months. The overall survival rates at 1, 3 and 5 years were 100.0%, 59.8% and 36.5%, respectively. The disease-free survival rates at 1, 3 and 5 years were 66.7%, 42.3% and 36.3%, respectively.


CONCLUSIONS
Primary lymphoma of the testis is preferably treated by multi-modality treatment. More than 6 cycles of chemotherapy is rational after orchiectomy. Regional radiotherapy tends to reduce the local relapse.
Yang
Jian-liang
JL
Department of Medical Oncology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing 100021, China.
Shi
Yuan-kai
YK
He
Xiao-hui
XH
Zhou
Ai-ping
AP
Liu
Peng
P
Ai
Bin
B
Zhang
Chang-gong
CG
D000328:Adult; D000368:Aged; D006801:Humans; D008223:Lymphoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery