[Serial topographic changes at the optic disc in normal-tension glaucoma viewed with scanning laser tomography].
OBJECTIVE
To evaluate topographic changes in normal-tension glaucoma using serial optic disc images obtained by scanning laser tomography.


METHODS
Fifty-six eyes of 30 patients with normal-tension glaucoma were imaged using the Heidelberg Retina Tomography (HRT) four or more times during follow-up periods of more than 3 years. Disc progression was determined by regression analysis of global and segmental changes in optic disc parameters. Visual field progression was determined by Humphrey Field Analyzer (HFA) program 30-2 and was compared with disc progression.


RESULTS
The global parameters of the optic disc showed progression in 21 of 56 eyes(37.5%). Progression was found in 30 eyes(53.6%) at the superotemporal segment, in 24 eyes(42.9%) at the temporal segment, in 27 eyes(48.2%) at the inferotemporal segment, in 21 eyes(37.5%) at the superonasal segment, in 23 eyes(41.1%) at the nasal segment, and in 27 eyes(48.2%) at the inferonasal segment. The visual field showed progression in 19 eyes (33.9%). The progression in the optic disc parameters did not necessarily agree with that in the visual field.


CONCLUSIONS
Glaucomatous disc changes over time can be determined with HRT using regression analysis.
Department of Ophthalmology, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan.
Akiko
A
Kato
Kazuhisa
K
Sugiyama
Yoshiki
Y
Kono
Hideya
H
Uchida
Goji
G
Tomita
Tetsuya
T
Yamamoto
D000328:Adult; D018450:Disease Progression; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods*; D009898:Optic Disk / Q000473:pathology*; D012044:Regression Analysis; D014057:Tomography, X-Ray Computed