Bioreactor state estimation and control.
Advanced control methods have been effectively employed for industrial chemical processing for decades. Only recently, however, have model-based strategies been implemented for biological processes. Some notable advances include the enhancement of metabolic flux models to describe the dynamic behavior observed in biochemical reactors. The combination of more than one type of model in a hybrid form was shown to perform well for bioprocess control applications.
Department of Chemical and Materials Engineering, San Jose State University, 1 Washington Square, San Jose, CA 95192-0082, USA. claire.komives@sjsu.edu
Claire
C
Komives
Robert S
RS
Parker
D000465:Algorithms; D018533:Biomass; D019149:Bioreactors; D003198:Computer Simulation; D006863:Hydrogen-Ion Concentration; D008962:Models, Theoretical; D013696:Temperature