Concurrent renal cell carcinoma and transitional cell carcinoma in a chronic hemodialysis patient.
A 60-year-old female patient had been on maintenance hemodialysis for 12 years was suffering from gross hematuria. Subsequent image studies revealed left renal and ureteral tumors. She then received left radical nephroureterectomy. Histological examination revealed the renal tumor was renal cell carcinoma and ureteral tumor was transitional cell carcinoma respectively. To our knowledge, this is the first reported case of simultaneous occurrence of these two urological cancers in a chronic hemodialysis patient. Our case may imply the increased susceptibility of urological malignancy in dialysis patients. Physicians should always raise the possibility of urological malignancy when a dialysis patient with gross hematuria is encountered. A thorough and careful screening for the malignancy should be performed on a regular basis in these patients with high risk.
Division of Nephrology, Department of Internal Medicine, Chang-Gung Memorial Hospital, Kaohsiung, Taiwan. ctlee33@adm.cgmh.org.tw
Chien-Te
CT
Lee
Jui-Wei
JW
Lin
Kenneth
K
Hsu
Tai-Yi
TY
Chen
Jin-Bor
JB
Chen
D002292:Carcinoma, Renal Cell / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant; D006435:Renal Dialysis; D014516:Ureteral Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D013520:Urologic Surgical Procedures / Q000379:methods