Involvement of the liver by multiple myeloma as nodular lesions: a case diagnosed by fine-needle aspiration and immunocytochemistry.
Liver involvement by multiple myeloma as space-occupying lesions is a rare condition with only a few cases reported in the literature. We present a case of a 68-year-old man with a prostatic adenocarcinoma who developed a multiple myeloma as a second primary malignancy. Hepatic nodules were discovered in the tomographic study. Fine-needle aspiration of one of the hepatic lesions showed a pleomorphic plasmacytoid tumor. Immunocytochemistry using p63 and kappa-chain antibodies was useful in determining the plasmacytic nature of the cells.
Service of Anatomic Pathology, Clinica Ponferrada, Ponferrada-Leon, Spain. gpyauflowerlion@terra.es
A
A
Fernandez-Flores
J
J
Fortes
A
A
Smucler
M
M
Orduña
A
A
Pol
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008565:Membrane Proteins / Q000378:metabolism; D016609:Neoplasms, Second Primary / Q000378:metabolism / Q000473:pathology*; D010954:Plasmacytoma / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*
C081876:CKAP4 protein, human; D007145:Immunoglobulin kappa-Chains; D008565:Membrane Proteins