[A case of multibacillary leprosy].
We report a 74-year-old Japanese man who occurred leprosy at the age of 68. He moved to Bolivia at the age of 33 as an immigrant. He complained erythematous plaques on his trunk and extremeties and dysuria. Skin biopsy specimen revealed granulomatous lesions and acid fast staining showed numerous number of positively stained bacilli. He was diagnosed as multibacillary leprosy and MDT containing DDS, RFP, and CLF was started. During the treatment, he developed borderline reaction twice presenting severe pain and marked swelling on his hand and foot. The reaction was successfully treated with daily dose of 50 mg prednisolone combined with anti-leprosy drugs. SPFX, MINO, and CAM were not able to be used due to the side effects. One year has been passed after the stop of treatment without relapse.
Sugita
Yasuyuki
Y
Department of Dermatology, Yokohama City University School of Medicine, Sugita Dermatological Clininc, 893 Nishiya-cho, Hodogaya-ku, Yokohama 240-0052, Japan.
Yoshinaka
Makoto
M
Mukawa
Rumi
R
Oonuma
Sumi
S
Ishii
Norihisa
N
Nakajima
Hiroshi
H
D000368:Aged; D001838:Bolivia; D004359:Drug Therapy, Combination; D004641:Emigration and Immigration; D006801:Humans; D007564:Japan; D007917:Leprostatic Agents / Q000008:administration & dosage; D007918:Leprosy / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D016896:Treatment Outcome
D007917:Leprostatic Agents; D011239:Prednisolone