[Perinatal management of triplet pregnancies from 1997 to 2001].
BACKGROUND
Because of the trend for premature birth, multifetal pregnancies are at high risk for neonatal morbidity and mortality. This study presents our perinatal management scheme and the outcome of triplet pregnancies.


METHODS
From 1997 to 2001 we studied 31 triplet pregnancies. Their management consisted of cervical measurement at 20 weeks, admission from 25 weeks onwards, regular ultrasound examinations, intravenous tocolysis with preterm contractions or cervical shortening, promotion of fetal lung maturation, antibiotic therapy with evidence of vaginal infection, delivery by caesarean section ideally at 33 weeks.


RESULTS
In the studied group 4 triplet pregnancies were monochorionic, 6 dichorionic, and 21 (68 %) trichorionic. 2/31 triplet pregnancies finalized in late abortions. Furthermore, a single and a double intrauterine death occured in two triplet pregnancies. 6 (21 %) of triplet pregnancies were delivered before the 30th week and 23 (79 %) after the 30th week of gestation (median gestational age 31.5 weeks, median birth weight 1545g). Neonates of trichorionic pregnancies in comparison to those of mono- and dichorionic pregnancies were delivered two to three weeks later and presented with significantly higher birth weights (1660 g vs. 1245 g vs. 1240 g; p = 0.001 and 0.0009, respectively). 13/84 (15.5 %) of the neonates showed growth retardation. In 4/84 (4.1 %) children brochopulmonary dysplasia or cerebral haemorrhage was observed. Only one child developed enterocolitis. 19 % (16/84) of neonates showed evidence of retinopathy. No intrauterine death occured after 28 weeks and no child died after delivery.


CONCLUSIONS
With our well defined management of triplet pregnancies from 20 weeks onwards we reach similar gestational ages at delivery but remarkably lower neonatal complication rates compared to previous studies.
Universitätsfrauenklinik Leipzig, Philipp-Rosenthal-Str. 55, 04103 Leipzig. milobh@medizin.uni-leipzig.de
H
H
Missfelder-Lobos
B
B
Viehweg
Ch
Ch
Vogtmann
R
R
Faber
D002585:Cesarean Section / Q000379:methods*; D005260:Female; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000209:etiology; D008168:Lung / Q000196:embryology; D008297:Male; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D011295:Prenatal Care / Q000379:methods*; D015145:Tocolysis; D014310:Triplets; D016216:Ultrasonography, Prenatal