Correlations between preprocedure mood and clinical outcome in patients undergoing coronary angioplasty.
We studied the relationship between mood and mood shift immediately before percutaneous coronary intervention (PCI) and 3 end points: total ischemic burden during PCI, adverse cardiac end points (ACE) after PCI, and death by 6-month follow up. Patients (n = 119) with unstable angina or myocardial infarction completed a visual analog scale (VAS) twice before PCI; before and after a session of stress relaxation, imagery, or touch; or approximately 30 minutes apart for patients assigned to prayer or to standard care. VAS included happiness, satisfaction, calm, hope, worry, shortness of breath, fear, and sadness. We observed a significant correlation between higher hope score before PCI and lower ischemic burden. Patients who experienced ACE had significantly lower hope and happiness scores than those who did not. Patients who survived to 6 months had significantly greater increases in worry and in hope. Our data suggest correlations between simple mood assessments before PCI and clinical outcomes during and after the procedure. More study is needed to understand whether attempts to alter patient mood can affect clinical outcomes.
Division of Cardiology, Department of Medicine, Durham Veterans Administration Medical Center and the Duke Clinical Research Institute, Durham, North Carolina, USA.
Gregory E
GE
Grunberg
Suzanne W
SW
Crater
Cynthia L
CL
Green
Jon
J
Seskevich
James D
JD
Lane
Harold G
HG
Koenig
Thomas M
TM
Bashore
Kenneth G
KG
Morris
Daniel B
DB
Mark
Mitchell W
MW
Krucoff
D000368:Aged; D000789:Angina, Unstable / Q000523:psychology* / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000523:psychology* / Q000628:therapy; D010147:Pain Measurement; D012189:Retrospective Studies; D016896:Treatment Outcome