Effect of aortic valve replacement on c-reactive protein in nonrheumatic aortic stenosis.
Plasma levels of C-reactive protein were higher in 20 patients with bicuspid or trileaflet degenerative aortic stenosis than in 31 normal controls and in 19 patients with pure aortic regurgitation. C-reactive protein decreased from before to 6 months after aortic valve replacement for aortic stenosis. These observations suggest that aortic stenosis is an inflammatory disease.
Gerber
Ivor L
IL
Cardiology Department, Green Lane Hospital, Auckland, New Zealand.
Stewart
Ralph A H
RA
Hammett
Christopher J K
CJ
Legget
Malcolm E
ME
Oxenham
Helen
H
West
Teena M
TM
French
John K
JK
White
Harvey D
HD
D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000097:blood / Q000175:diagnosis / Q000601:surgery; D012720:Severity of Illness Index
D002097:C-Reactive Protein