[Clinical and pathological features of 23 patients with primary lymphoma of the testis].
OBJECTIVE
To study the clinical and pathological features of primary lymphoma of the testis and try to find out the rational treatment modality.


METHODS
Retrospective and follow-up analysis was conducted in 23 patients with primary lymphoma of the testis. Survival analysis was performed by Kaplan-Meier process.


RESULTS
The primary clinical symptom was painless tumefaction. 78.3% lesions were Stage I(E) on diagnosis. Most of them were intermediate grade B cell lymphoma. All patients received orchiectomy followed by chemotherapy and some followed by radiotherapy. The median survival time was 42 months. The overall survival rates at 1, 3 and 5 years were 100.0%, 59.8% and 36.5%, respectively. The disease-free survival rates at 1, 3 and 5 years were 66.7%, 42.3% and 36.3%, respectively.


CONCLUSIONS
Primary lymphoma of the testis is preferably treated by multi-modality treatment. More than 6 cycles of chemotherapy is rational after orchiectomy. Regional radiotherapy tends to reduce the local relapse.
Department of Medical Oncology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing 100021, China.
Jian-liang
JL
Yang
Yuan-kai
YK
Shi
Xiao-hui
XH
He
Ai-ping
AP
Zhou
Peng
P
Liu
Bin
B
Ai
Chang-gong
CG
Zhang
D000328:Adult; D000368:Aged; D006801:Humans; D008223:Lymphoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery