Recurrent transverse myelitis in primary antiphospholipid syndrome--case report and literature review.
Transverse myelitis is an uncommon but well-known neurologic complication of systemic lupus erythematosus, and antiphospholipid antibodies have been implicated as having a pathogenic role of myelopathy in primary and secondary antiphospholipid syndrome. Transverse myelitis usually is monophasic, but recurrent transverse myelitis was reported in association with systemic lupus erythematosus, multiple sclerosis, and spinal arteriovenous malformations. It has been reported extremely rarely in patients with primary antiphospholipid syndrome. Herein we describe a patient with both conditions and propose that recurrent transverse myelitis should be included as a very rare feature of primary antiphospholipid syndrome.
Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, 634-18 Keumam Dong, Dukjin Gu, Chonju, Chonbuk 561-712, Korea.
J H
JH
Kim
S I
SI
Lee
S I
SI
Park
W H
WH
Yoo
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009188:Myelitis, Transverse / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012008:Recurrence; D013116:Spinal Cord / Q000473:pathology; D013904:Thoracic Vertebrae; D016896:Treatment Outcome
D005938:Glucocorticoids; D008775:Methylprednisolone