Wegener's granulomatosis diagnosed by testicular biopsy.
Urogenital involvement, other than the kidneys, is extremely rare in Wegener's granulomatosis (WG) and occurs in less than 1% of the cases. When encountered it is confined to prostate, bladder, urethra, cervix, and vagina. Granulomatous infiltration of the testis from WG has not been cited in the medical literature. We report a case of WG in a Hispanic male who presented with sensorineural hearing loss and hemoptysis. He had a pulmonary lesion and a painless right testicular mass, which was found to have necrotizing granulomas on excisional biopsy. This may be the first reported case of WG diagnosed by testicular biopsy as testicular involvement is rare in WG. We believe that the actual incidence of testicular involvement in WG may be higher as genital examination may be ignored during routine physical examinations.
Division of Nephrology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Mahendra
M
Agraharkar
Sumita
S
Gokhale
Rajiv
R
Gupta
D001706:Biopsy; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013733:Testicular Diseases / Q000473:pathology*; D013737:Testis / Q000473:pathology*