Risk factors influencing mortality of patients with severe acute pancreatitis within 24 hours after admission.
OBJECTIVE
To study the risk factors for death of patients with severe acute pancreatitis (SAP) within 24 hours after admission.


METHODS
Clinical and laboratory data of 74 patients with SAP were analyzed retrospectively. The 27 possible risk factors for death within 24 hours after admission were investigated using logistic regression (SPSS software package 10.0), and the equation of logistic regression was set up.


RESULTS
Among the 27 possible risk factors, arterial pH, APACHE II scores, early shock, multiple organ failure were associated with mortality. Single logistic regression analysis of the 27 parameters showed that early shock, pleural effusion, arterial pH, complications and APACHE II scores were associated with death of SAP patients, but using multiple logistic regression analysis showed that only acidosis (pH<7.35) was associated with death.


CONCLUSIONS
To maintain the function of organs and correct dysequilibrium of water-electrolyte and acid-base in early treatment of SAP is essential to lower the mortality.
Zhu
Ai-Jun
AJ
Laboratory of Hepatobiliary Surgery, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China. zhaj_1023@163.com
Shi
Jing-Sen
JS
Sun
Xue-Jun
XJ
D018806:APACHE; D000138:Acidosis / Q000401:mortality*; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D005260:Female; D006760:Hospitalization; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000401:mortality*; D012307:Risk Factors; D012720:Severity of Illness Index