[Exacerbation of aspirin-induced asthma associated with RSV infection].
We report the case of a 60 year old woman, suffering for 8 years from aspirin-induced asthma, having an airway infection of RSV-respiratory syncytial virus. New methods of molecular biology were used to identify the virus in the lung bioptate (RT-PCR, reverse transcription polymerase chain reaction and nested PCR). The role of viruses, especially RNA, is still unknown in pathogenesis of asthma. The reported case could help to explain their participation in this disease.
II Katedra Chorób Wewnetrznych Collegium Medicum Uniwersytet Jagielloński, 31-066 Kraków, ul. Skawińska 8.
Elzbieta
E
Filipowicz
Marek
M
Sanak
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000821:virology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012367:RNA, Viral; D018357:Respiratory Syncytial Virus Infections / Q000235:genetics / Q000821:virology*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012720:Severity of Illness Index
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012367:RNA, Viral; D001241:Aspirin