Disseminated cutaneous granulomatous eruption occurring in the setting of myelodysplasia.
A 66-year-old woman with a myelodysplastic syndrome developed a widespread, pruritic, nodular eruption. A skin-biopsy specimen showed a granulomatous infiltrate, with no evidence of clonality; a bone-marrow biopsy showed possible transition to acute myeloid leukemia. This presentation is consistent with two prior reports of granulomatous eruptions occurring in the setting of myelodysplasia.
Katz
Kenneth A
KA
Ronald O. Perelman Department of Dermatology, New York University, USA.
D000368:Aged; D002471:Cell Transformation, Neoplastic; D005260:Female; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000473:pathology; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology