A new naphthopyrone from the root of Pleuropterus ciliinervis.
A new naphthopyrone, pleuropyrone A (1), together with (-)-lyoniresinol 3a-O-beta-D-glucopyranoside (2) and (+)-lyoniresinol 3a-O-beta-D-glucopyranoside (3) was isolated from the roots of Pleuropterus ciliinervis. The structure of pleuropyrone A (1) was determined to be 2,5-dimethyl-8-hydroxynaphthopyrone 10-O-beta-D-glucopyranoside by spectroscopic methods including 2D-NMR. Compounds 2 and 3 showed moderate antioxidant activity.
Laboratory of Immunomodulator, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea. baekh@cnu.ac.kr
Byung-Sun
BS
Min
Jong-Pill
JP
Lee
Min-Kyun
MK
Na
Ren-Bo
RB
An
Sang-Myung
SM
Lee
Hyeong-Kyu
HK
Lee
KiHwan
K
Bae
Sam-Sik
SS
Kang
D000818:Animals; D000975:Antioxidants / Q000737:chemistry; D001713:Biphenyl Compounds; D001923:Brain Chemistry / Q000187:drug effects; D002241:Carbohydrates / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D010851:Picrates / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D019664:Polygonaceae / Q000737:chemistry*; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification; D051381:Rats; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
C487321:2,5-dimethyl-8-hydroxynaphthopyrone 10-O-beta-D-glucopyranoside; D000975:Antioxidants; D001713:Biphenyl Compounds; D002241:Carbohydrates; D009281:Naphthalenes; D010851:Picrates; D011753:Pyrones; D017392:Thiobarbituric Acid Reactive Substances; D013481:Superoxides; C004931:1,1-diphenyl-2-picrylhydrazyl