Spontaneous complete regression of hepatocellular carcinoma with portal vein tumor thrombus.
We report herein a case of spontaneous complete regression of hepatocellular carcinoma with portal vein tumor thrombus. A 69-year-old Japanese man with chronic hepatitis C was admitted to our hospital, because of a large mass in the right hepatic lobe. He was diagnosed with hepatocellular carcinoma based on computed tomography and the elevated serum levels of alpha-fetoprotein. Abdominal angiography revealed portal vein tumor thrombus. Approximately 2 months after the initial diagnosis, alpha-fetoprotein had decreased to a normal range. Under a diagnosis of hepatocellular carcinoma, a right hepatic lobectomy was performed, and histological examination of the resected specimen revealed no viable tumor cells. The patient is alive 1 year after the surgery without evidence of recurrence.
Department of Surgery, Niigata University School of Medicine, 1-757 Asahimachi-dori, Niigata City, 951-8510 Japan. iiaitss@dia-net.ne.jp
Tsuneo
T
Iiai
Yoshinobu
Y
Sato
Nobuyuki
N
Nabatame
Satoshi
S
Yamamoto
Shigeto
S
Makino
Katsuyoshi
K
Hatakeyama
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D009360:Neoplastic Cells, Circulating; D011169:Portal Vein; D011172:Portography; D014057:Tomography, X-Ray Computed