Equine leukocyte antigen system. I. Serological studies.
Lymphocytotoxic alloantibodies have been recognized in primiparous mare sera and colostra using the two-step microcytotoxicity test. The antigens detected on the leukocyte membrane do not occur on the erythrocytes. After testing on a cell panel from unrelated horses, absorptions with leukocytes were carried out. The subsequent retesting of the serum reagents on a cell panel including cells from 24 families rendered possible a grouping of preliminary monospecific reagents characterizing 18 antigen specificities on the cell membrane.
Institute for Clinical Immunology, Inselspital, Horse Clinic of the Veterinary School, University of Berne, Berne, Switzerland.
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S
Lazary
A L
AL
de Weck
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S
Bullen
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R
Straub
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Gerber
D000818:Animals; D003126:Colostrum / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D005260:Female; D006680:HLA Antigens / Q000276:immunology*; D006736:Horses / Q000276:immunology*; D007518:Isoantibodies / Q000097:blood; D007962:Leukocytes / Q000276:immunology*; D013045:Species Specificity
D006680:HLA Antigens; D007518:Isoantibodies