[New radiotherapy techniques in the treatment of patients with craniopharyngioma: a report of two cases].
The authors report two cases of adult patients with craniopharyngioma recurrence after surgery. In both these patients radiotherapy resulted in a complete regression of the neoplasms, confirmed both by clinical examination and MR imaging. In both cases modern radiotherapy techniques were used so as to spare healthy tissues surrounding the tumor. Case 1. A 56-year-old man was admitted with an extensive (3.5 x 4.0 x 4.0 cm) recurrent craniopharyngioma 3 years after the initial surgery and 3 months after a surgery for relapse. Conformal 3-D planned fractionated radiotherapy to the total dose of 54 Gy in 30 fractions was delivered encompassing the tumor with 5 mm margins. Four months after radiotherapy MR imaging demonstrated a complete regression of the neoplasm and the patient recovered totally from his endocrine deficiency and neurological symptoms. Case 2. A 29-year-old man was irradiated 10 months after the initial surgery when a relapse of craniopharyngioma was found in MR imaging. The largest diameter of this recurrent tumor was 18 mm. The patient was subjected to fractionated stereotactic radiotherapy to the total dose of 54 Gy in 27 fractions. Two months after the treatment his complete recovery was confirmed by MRI. Benefits resulting from the use of more recent radiotherapy techniques in the management of craniopharyngioma are discussed.
Zakładu Teleradioterapii, Zakładu Radiologii, Zakładu Fizyki Medycznej, Centrum Onkologii-Instytut, Warszawa.
Lucyna
L
Kepka
Jakub
J
Pałucki
Jacek
J
Fijuth
Maria
M
Kawczyńska
D000328:Adult; D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology / Q000532:radiotherapy*; D003397:Craniopharyngioma / Q000378:metabolism / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents