In vivo evaluation of plasma sprayed hydroxyapatite coatings having different crystallinity.
In this paper, hydroxyapatite (HA) coatings having the crystallinities of 56% and 98% were deposited by the plasma spraying and vapor-flame treatment process. The phase composition and crystallinity of the coatings were investigated by X-ray diffraction and infrared spectra. The dissolution behavior of the coatings in tris-buffer solutions was examined. The results obtained indicated that the coating having the high crystallinity showed the lower dissolution as compared to the low crystallinity coating. The bone bonding ability of HA coatings were observed in vivo by implanted in dog's femur. After 3 months implantation, the high crystallinity coating showed the higher shear strengths and remained integrated, whereas the separation of the coating fragments was clearly observed in the coating having low crystallinity.
Shanghai Institute of Ceramics, Chinese Academy of Science, 1295 Dingxi Road, Shanghai 200050, People's Republic of China. xueweichang@163.com
Weichang
W
Xue
Shunyan
S
Tao
Xuanyong
X
Liu
XueBin
X
Zheng
Chuanxian
C
Ding
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D018786:Bone Substitutes; D002021:Buffers; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003460:Crystallization; D004285:Dogs; D017886:Durapatite / Q000737:chemistry*; D005269:Femur / Q000473:pathology; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties; D013718:Tensile Strength; D013997:Time Factors; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D018786:Bone Substitutes; D002021:Buffers; D020099:Coated Materials, Biocompatible; D017886:Durapatite