The role of immunosuppression in recurrence of hepatitis C.
1. Recurrent hepatitis C is an increasing problem posttransplantation. 2. It is difficult to determine histologically if alloimmunity, i.e., rejection, is also plays a role in posttransplantation hepatitis C. 3. Change in the degree of immunosuppression, rather than the absolute amount of immunosuppression, is bad for HCV-infected recipients. 4. Corticosteroid boluses are bad for HCV-infected recipients.
Lake
John R
JR
Gastroenterology Division, University of Minnesota, Minneapolis, MN 55455, USA. lakex009@tc.umn.du
D006084:Graft Rejection / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D006526:Hepatitis C / Q000276:immunology* / Q000601:surgery; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation / Q000276:immunology; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012367:RNA, Viral / Q000097:blood; D012008:Recurrence
D007166:Immunosuppressive Agents; D012367:RNA, Viral; D009173:Mycophenolic Acid