Two new 24-isopropenyl-lanostanoids from Tillandsia brachycaulos.
The leaves of Tillandsia brachycaulos afforded two novel tetracyclic triterpenoids identified as (24S)-24-isopropenyl-29-nor-5alpha-lanosta-7-en-3beta-ol (1) and (24S)-24-isopropenyl-29-nor-5alpha-lanosta-7-en-3-one (2), in addition to the known isopimaric acid (3) and chlorogenic acid (4). Their structures were elucidated on the basis of spectral analysis, including homo- and heteronuclear correlation NMR experiments (COSY, ROESY, HMQC and HMBC) and by comparison with data in the literature. The antimicrobial and antifungal activities were studied. The compounds did not show significant activity.
Laboratorio de Química Orgánica de Investigación, Facultad de Química, Universidad Aut6noma de Yucatán, Calle 41 No. 421, Col. Industrial, C. P. 97150, Mérida, Yucatán, Mexico.
Zulema
Z
Cantillo-Ciau
Gonzalo J
GJ
Mena-Rejón
Esther
E
Quintero-Mármol
Antonio
A
Jiménez-Díaz
Leovigildo
L
Quijano
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D007810:Lanosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031232:Tillandsia / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts; D007810:Lanosterol