The use of hepatitis C-infected grafts in liver transplantation.
1. Liver grafts from hepatitis C virus (HCV)-infected deceased donors can be used safely in HCV-infected recipients. 2. Histological assessment of the graft before orthotopic liver transplantation (OLT) is advised. 3. Recipients of these grafts should give consent accordingly. 4. The course of HCV disease after OLT parallels that in patients who received noninfected organs.
Department of Medicine, Mayo Clinic Scottsdale, AZ, USA.
Juan I
JI
Arenas
Hugo E
HE
Vargas
Jorge
J
Rakela
D018572:Disease-Free Survival; D005838:Genotype; D006085:Graft Survival / Q000502:physiology; D016174:Hepacivirus / Q000235:genetics / Q000502:physiology; D006526:Hepatitis C / Q000601:surgery; D006801:Humans; D008099:Liver / Q000821:virology; D016031:Liver Transplantation / Q000401:mortality; D014019:Tissue Donors; D014184:Transplantation, Homologous; D016896:Treatment Outcome