Analysis of essential oil of Coridothymus capitatus (L.) and its antibacterial and antifungal activity.
The water-distilled essential oil the leaves of Coridothymus capitatus were analyzed by GC/MS and also analyzed by direct thermal desorption GC/MS. Comparison was made between two analyses techniques. The essential oil consisted mainly of monoterpenes 98.9%, while oxygenated hydrocarbons were identified as 55.6 % and non-oxygenated hydrocarbons as 43.6%. As major components were found carvacrol (35.6%), p-cymene (21.0%), thymol (18.6%), gamma-terpinene (12.3%), alpha-terpinene (3.2%), beta-myrcene (3.0%) and alpha-thujene (1.3%) by hydrodistillation and by the GC/MS method. The direct thermal desorption GC/MS analysis also showed the same major components, namely carvacrol (51.6%), thymol (21.7%), p-cymene (9.7%) gamma-terpinene (8.2%), alpha-terpinene (1.64%). The essential oil of C. capitatus showed strong activity against S. aureus, P. vulgaris, P. aeruginosa, E. coli, K. pneumonia, B.
Goren
Ahmet C
AC
Tubitak, Marmara Research Center, Materials and Chemical Technologies Research Institute, PO Box 21, 41470 Gebze, Kocaeli, Turkey. ahmet.goren@ume.tubitak.gov.tr
Bilsel
Gokhan
G
Bilsel
Mine
M
Demir
Huseyin
H
Kocabaş
E Esin
EE
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013816:Thermodynamics
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009822:Oils, Volatile; D013729:Terpenes