[The psychosocial approach to the planning and implementation of vaccine trials for HIV infection].
The production of an effective vaccine for HIV infection is one of the major challenges for the third millennium public health. Here we review published studies addressing the issue of incentives and barriers influencing the choice to participate in a vaccine trial. Currently available literature clearly indicates the need to include psychosocial dimensions in the preparation and implementation of vaccine trials. The underestimation of participants' satisfaction about information communication may lead to non-adherence and to drop-out from the trials. Proper attention to communication skills of professionals involved in participants' enrollment and follow-up is essential to ensure trial success.
Starace
Fabrizio
F
Servizio Psichiatria di Consultazione ed Epidemiologia Comportamentale, Ospedale D. Cotugno, Via G. Quagliariello 54, 80131 Napoli. fabrizio.starace@tin.it
Embrione
Francesco
F
Fusco
Maria Luigia
ML
Cafaro
Loredana
L
D016915:AIDS Vaccines; D002986:Clinical Trials as Topic / Q000523:psychology*; D003142:Communication; D003657:Decision Making; D006801:Humans; D009042:Motivation; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D010352:Patient Dropouts; D017060:Patient Satisfaction; D018579:Patient Selection; D010817:Physician-Patient Relations; D011584:Psychology; D035842:Research Subjects / Q000191:economics / Q000523:psychology*; D035502:Trust; D014611:Vaccination / Q000523:psychology*
D016915:AIDS Vaccines