Medical problems occurring during the long-term follow-up after liver transplantation.
Liver transplantation is a standardized therapy for end-stage liver disease. With current immunosuppressive protocols and patient care, ten-year patient survival rate has reached 60%. Several medical complications may develop during this period, including renal dysfunction, hypertension, diabetes mellitus, hyperlipidemia, and metabolic bone disease. The aim of this article is to analyze long-term results of several clinical trials reporting common medical dysfunctions after liver transplantation and to discuss their management.
Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital, Geneva, Switzerland.
A
A
Demirag
L H
LH
Bühler
P
P
Majno
Th
T
Berney
M
M
Chilcott
E
E
Giostra
Ph
P
Morel
G
G
Mentha
D002423:Cause of Death; D002986:Clinical Trials as Topic; D005500:Follow-Up Studies; D006801:Humans; D017093:Liver Failure / Q000401:mortality / Q000601:surgery*; D016031:Liver Transplantation / Q000401:mortality; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D016019:Survival Analysis; D017741:Survivors; D013557:Switzerland