[Abnormal cerebrovascular reactivity in patients with asymptomatic atherosclerosis of the carotid arteries].
The study included 53 patients (males at the age of 44-78 years) with ischemic heart disease and arterial hypertension with asymptomatic unilateral atherosclerotic affection of carotid arteries (CA). Ultrasonic investigation registered 30-80% stenosis of carotid arteries in the absence of neurological deficit. Cerebrovascular reactivity was assessed by means of the hypercapnic hypoxic test (HHT) including breathing via additional "dead space" for 3 min. Initial and peak linear velocity of the blood flow in the middle cerebral artery was measured with ultrasonic transcranial dopplerography. By HHT results, three types of cerebral vascular reactions in patients with combined atherosclerosis of coronary and carotid arteries were identified: subnormal dilatation on the side of stenosed internal carotid artery, increased dilatation and paradoxical vasoconstriction on the affected side. Cerebrovascular reactivity and the type of atherosclerotic plaques did not collerate.
Astanina
I A
IA
Dudko
V A
VA
Vorozhtsova
I N
IN
D000328:Adult; D000368:Aged; D002340:Carotid Artery Diseases / Q000209:etiology / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology; D003324:Coronary Artery Disease / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged