The chemokine receptor, CCR5.
The chemokine receptor, CCR5, is a G protein coupled receptor responsible for some of the effects of the chemokines CCL3, CCL4 and CCL5. It is also one of the co-receptors for the entry of human immunodeficiency virus-1 (HIV-1) into cells. Regulation of CCR5 number on cells is, therefore, important for determining the infection rate by HIV-1.
School of Animal and Microbial Sciences, University of Reading, P.O. Box 228, Whiteknights, RG6 6AJ, Reading RG6 6AJ, UK.
Anja
A
Mueller
Philip G
PG
Strange
D000595:Amino Acid Sequence; D000818:Animals; D002893:Chromosomes, Human, Pair 3; D016368:Frameshift Mutation; D005787:Gene Frequency; D015658:HIV Infections / Q000276:immunology; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D011110:Polymorphism, Genetic; D017433:Protein Structure, Secondary; D019713:Receptors, CCR5 / Q000737:chemistry* / Q000235:genetics / Q000276:immunology / Q000502:physiology*
D019713:Receptors, CCR5