Botulinum toxin in the management of bowel and bladder function in spinal cord injury and other neurologic disorders.
Botulinum toxin inhibits release of acetylcholine and other neurotransmitters. It has been used successfully to treat pain and abnormal skeletal and smooth muscle activity in patients. This article discusses its use in patients with bladder and bowel disorders.
Dykstra
Dennis D
DD
Department of Physical Medicine and Rehabilitation, MMC #297, University of Minnesota, Minneapolis, MN 55455, USA. dykst001@maroon.tc.umn.edu
D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use*; D001004:Anus Diseases / Q000188:drug therapy; D020211:Autonomic Dysreflexia / Q000188:drug therapy / Q000209:etiology; D001905:Botulinum Toxins / Q000627:therapeutic use*; D003248:Constipation / Q000188:drug therapy; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D013119:Spinal Cord Injuries / Q000150:complications*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy* / Q000209:etiology
D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins