New Pyrrolizidine Alkaloids and Glycosides from Anchusa strigosa.
Six new pyrrolizidine alkaloids, a new carboxylic acid, a new phenolic and a new oleanane glycoside, together with the known compounds 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyltetrahydrofuran 4'-O-beta-D-glucopyranoside, rosmarinic acid, caffeic acid, tormentic acid 28-O-beta- D-glucopyranoside, euscaphic acid 28-O-beta-D-glucopyranoside, euscaphic acid, and allantoin were isolated from Anchusa strigosa roots. Their structures were established by high resolution NMR, MS, elemental analysis, and chemical reactions.
Braca
Alessandra
A
Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126 Pisa, Italy. braca@farm.unipi.it
Bader
Ammar
A
Siciliano
Tiziana
T
Morelli
Ivano
I
De Tommasi
Nunziatina
N
D028082:Boraginaceae; D006027:Glycosides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots; D011763:Pyrrolizidine Alkaloids / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*
D006027:Glycosides; D010936:Plant Extracts; D011763:Pyrrolizidine Alkaloids