[Two cases of radiation myositis probably induced by recall phenomenon].
Two cases of radiation myositis following gemcitabine-based chemotherapy for advanced non-small cell lung cancer are presented. In the two cases, myositis appeared 3 and 5.5 months after the completion of radiation therapy and 2 and 2.5 months after the beginning of chemotherapy, respectively. The affected areas, the upper back and right thigh, appeared as areas of increased signal intensity on T2-weighted MR imaging and were enhanced by the administration of Gd-DTPA in the skeletal muscles. These coincided with the previously irradiated area. Although radiation myositis is a rare complication, it is important to be careful of radiation recall induced by chemotherapeutic agents.
Department of Radiology, Onoda City Hospital.
Gouji
G
Miura
Tsuneo
T
Matsumoto
Nobuyuki
N
Tanaka
Takuya
T
Emoto
Takeo
T
Kawamura
Naofumi
N
Matsunaga
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000209:etiology*; D011838:Radiation-Sensitizing Agents / Q000009:adverse effects*; D011878:Radiotherapy / Q000009:adverse effects*; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D011838:Radiation-Sensitizing Agents; D003841:Deoxycytidine; D000093542:Gemcitabine