Does the tonsillar surface flora differ in children with and without tonsillar disease?
OBJECTIVE
To investigate whether the tonsillar flora differ in children with and without adenotonsillar disease.


METHODS
Tonsil surface swabs were taken from 218 children indicated for adenotonsillectomy because of moderate symptoms of recurrent tonsillopharyngitis or adenotonsillar hypertrophy (T+Ads group). Control swabs were taken from 100 children without symptoms of adenotonsillar disease who visited the ophthalmology clinic. Potential respiratory pathogens were identified.


RESULTS
Potential respiratory pathogens were found in 54% of the T+Ads group, compared to 41% of the control group (p = 0.04). Haemophilus influenzae was the commonest pathogen in both groups, being found in 41% of the T+Ads group and 34% of the control group. Moraxella catarrhalis was found more often in the T+Ads group compared to the control group: 7% vs 0% (p = 0.004). H. influenzae was found in 32% of the children with recurrent tonsillitis, compared to 48% of the children with symptoms of tonsillar hypertrophy (p = 0.03).


CONCLUSIONS
The prevalence of potential respiratory pathogens on the tonsillar surface of children with moderate symptoms of recurrent tonsillopharyngitis and/or tonsillar hypertrophy differs only slightly from that in children without symptoms of adenotonsillar disease. Variations in the microbial flora do not seem to play an essential role in the predisposition of these children to tonsillar disease.
Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands. b.k.vanstaaij@med.uu.nl
Birgit K
BK
Van Staaij
Emma H
EH
Van Den Akker
Elisabeth H M
EH
De Haas Van Dorsser
Andre
A
Fleer
Arno W
AW
Hoes
Anne G M
AG
Schilder
D000233:Adenoidectomy; D000234:Adenoids / Q000382:microbiology / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D006984:Hypertrophy / Q000382:microbiology; D008297:Male; D001936:Moraxella catarrhalis / Q000302:isolation & purification*; D014066:Palatine Tonsil / Q000382:microbiology* / Q000473:pathology; D010612:Pharyngitis / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D014068:Tonsillectomy; D014069:Tonsillitis / Q000382:microbiology* / Q000601:surgery