Total synthesis and structural confirmation of malayamycin A: a novel bicyclic C-nucleoside from Streptomyces malaysiensis.
[reaction: see text] The stereocontrolled synthesis of malayamycin A, a novel naturally occurring bicyclic C-nucleoside of the perhydrofuropyran type, is described.
Hanessian
Stephen
S
Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-ville, Montréal, Quebec H3C 3J7, Canada. stephen.hanessian@umontreal.ca
Marcotte
Stéphane
S
Machaalani
Roger
R
Huang
Guobin
G
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D013302:Streptomyces / Q000737:chemistry*
D019086:Bridged Bicyclo Compounds, Heterocyclic; D009705:Nucleosides; C493874:malayamycin A