Catalytic asymmetric hydrogenation in a room temperature ionic liquid using chiral Rh-complex of ionic liquid grafted 1,4-bisphosphine ligand.
Introduction of imidazolium ionic liquid pattern to the catalyst not only avoided catalyst leaching but also increased the stability of catalyst in ionic liquid, and thus, the Rh-complex of 1,4-bisphosphine bearing two imidazolium salt moieties was successfully immobilized in an ionic liquid and reused several times for the hydrogenation of an enamide without significant loss of catalytic efficiency.
Lee
Sang-gi
SG
Life Sciences Division, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul 130-650, Korea. sanggi@kist.re.kr
Zhang
Yong Jian
YJ
Piao
Jing Yu
JY
Yoon
Hyeon
H
Song
Choong Eui
CE
Choi
Jung Hoon
JH
Hong
Jongki
J