[The change and implication of epididymis sialic acid following torsing/detorsing testes in rats].
OBJECTIVE
To investigate the change and implication of epididymis sialic acid after 24 hours following 2- or 4-hour torsing/detorsing of testes in rats.


METHODS
Twenty-four adult male Sprague-Dawley rats were subjected to unilateral 720 degrees testicular torsion for 2 and 4 hours and then repaired. The ischemic epididymides were collected for detecting the content of sialic acid by spectrophotometry.


RESULTS
There was no statistically significant difference between the content of epididymis sialic acid after 24 hours following 2-hour torsing/detorsing of testes and that of the sham group, while significant difference was found between the content of epididymis sialic acid after 24 hours following 4-hours torsing/detorsing of testes and that of sham group.


CONCLUSIONS
Sialic acidsecreting-function of epididymis can remain normal after one day following 2-hour torsing/detorsing of testes, and be injured after one day following 4-hour torsing/detorsing of testes. The epididymis remains resistant to ischemic damage during testicular ischemia.
Department of Urology, Zhongnan Hospital Affiliated to Wuhan University, Wuhan, Hubei 430071, China.
Yu-Gang
YG
Zhao
Xin-Min
XM
Zheng
Zhi-Wei
ZW
Yang
Shi-Wen
SW
Li
Li-Quan
LQ
Hu
D000818:Animals; D004822:Epididymis / Q000737:chemistry*; D008297:Male; D019158:N-Acetylneuraminic Acid / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013086:Spermatic Cord Torsion / Q000378:metabolism*; D013997:Time Factors
D019158:N-Acetylneuraminic Acid