Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophrenia.
We examined the occurrence of the -141C Ins/Del polymorphism in 93 Finnish patients with schizophrenia. In comparison with previous studies with Japanese and Caucasian populations, the incidence of this polymorphism was unexpectedly low. The findings suggest that the frequency of the -141C Ins/Del polymorphism is lower in Northern Europe compared to other Caucasian and Japanese populations.
Department of Psychiatry, University of Tampere, Medical School, Tampere, FIN-33014, Finland. olli.kampman@uta.fi
Olli
O
Kampman
Sami
S
Anttila
Ari
A
Illi
Terho
T
Lehtimäki
Kari M
KM
Mattila
Markus
M
Roivas
Esa
E
Leinonen
D000483:Alleles; D002872:Chromosome Deletion; D003431:Cross-Cultural Comparison; D003596:Cytosine / Q000378:metabolism*; D005060:Europe; D005387:Finland; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D007564:Japan; D016254:Mutagenesis, Insertional; D016017:Odds Ratio; D011110:Polymorphism, Genetic / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology
D017448:Receptors, Dopamine D2; D003596:Cytosine