An efficient preparation of 6(I,IV) dihydroxy permethylated beta-cyclodextrin.
We report on a straightforward synthesis of 2(I-VII),3(I-VII),6(II,III,V-VII)-nonadeca-O-methylcyclomaltoheptaose, a methylated beta-cyclodextrin derivative bearing two 6(I,IV) hydroxyl groups, from its easily available benzylated counterpart.
Lecourt
Thomas
T
Ecole Normale Supérieure, Département de Chimie, UMR 8642 CNRS, 24, rue Lhomond, 75231 Paris 05, France.
Mallet
Jean-Maurice
JM
Sinaÿ
Pierre
P
D003505:Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry*; D006900:Hydroxylation; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D015394:Molecular Structure; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D047392:beta-Cyclodextrins; C031215:betadex