Mononeuropathy multiplex in association with livedoid vasculitis.
Livedoid vasculitis is a chronic dermatological disorder associated with petechiae and recurrent, unusually shaped ulcers that heal to form hyperpigmentated areas and atrophie blanche. This condition is more correctly termed a vasculopathy, rather than a vascultis, and is often associated with an underlying hypercoagulable disorder. We report a patient with livedoid vasculitis and mononeuropathy multiplex. We propose that peripheral nervous system involvement arises from multifocal areas of ischemia due to fibrin and thrombin deposition within both the wall and lumen of vasa nervorum.
Toth
Cory
C
Department of Neurological Sciences, Room 165, Heritage Medical Research Building, University of Calgary, 3330 Hospital Dr. NW, Calgary, Alberta T2N 4N1, Canada. corytoth@shaw.ca
Trotter
Martin
M
Clark
Arthur
A
Zochodne
Douglas
D
D000328:Adult; D000842:Ankle / Q000473:pathology; D005260:Female; D006801:Humans; D020422:Mononeuropathies / Q000150:complications / Q000473:pathology*; D009475:Neurons, Afferent / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000150:complications* / Q000473:pathology*; D014657:Vasculitis / Q000150:complications / Q000473:pathology*