[Post-radiation effect on the interhemispheric asymmetry in EEG and thermography characteristics].
Complex analysis of EEG and thermographic parameters carried out in 10 healthy subjects and 34 patients, Chernobyl clean-up participants revealed a correlation between EEG and brain temperature changes in the baseline state and during mental arithmetic. During cognitive activity the maximal increase in the average EEG coherence and temperature shifts in healthy subjects were observed in the left frontotemporal and right parietotemporal areas. In patients changes in both parameters under study were most pronounced, the interhemispheric relations were impaired. The visual analysis revealed "flat" and "hypersynchronous" EEG types in patients. The dominant pathologic activity in the betal range indicative of mediobasal and oral brainstem lesions was characteristic of the flat EEG. This type of activity was observed in 60% of patients. In these cases, a general decrease in EEG coherence and temperature was most pronounced in the left hemisphere. The hypersynchronou EEG type (40% patients) was characterized by paroxysmal activity in the theta and alpha ranges suggesting diencephalic brain lesions. In these cases, EEG coherence and temperature were more variable; changes in the right hemisphere were significant, be it increase or decrease. Our complex approach to investigation of brain activity in different aspects seems to be promising in estimation of the brain functional state both in healthy persons and patients in remote terms after exposure to radiation. The specific hemispheric temperature changes revealed in Chernobyl patients especially during cognitive activity can be the sequels of postradiation disorders of vascular neuro-circulation. The EEG findings suggest subcortical disorders at different levels (diencephalic or brainstem) and functional failure of the right or left hemispheres in remote terms after exposure to radiation.
Institute of Higher Nervous Activity and Neurophysiology, Institute of Radiophysics and Electronics, Russian Academy of Sciences, Institute of Diagnostics and Surgery, Ministry of Public Health of the Russian Federation, Moscow.
L A
LA
Zhavoronkova
A V
AV
Gabova
G D
GD
Kuznetsova
A G
AG
Sel'skiĭ
V I
VI
Pasechnik
N B
NB
Kholodova
A V
AV
Ianovich
D001921:Brain / Q000528:radiation effects*; D003071:Cognition / Q000528:radiation effects*; D004569:Electroencephalography / Q000528:radiation effects*; D007839:Functional Laterality / Q000528:radiation effects*; D006801:Humans; D011832:Radiation Injuries / Q000175:diagnosis*; D018788:Radioactive Hazard Release; D013817:Thermography / Q000379:methods*