Potential role of interleukin-1 at the peri-ovulation stage in a species of placental viviparous reptile, the three-toed skink, Chalcides chalcides (Squamata: Scincidae).
We recently showed that interleukin-1 (IL-1) is secreted by the placenta of a species of squamate reptile, the three-toed skink, Chalcides chalcides. In this study, we used immunohistochemical techniques to investigate the expression of IL-1 (in the two isoforms, IL-1alpha and IL-1beta) and its specific membrane receptor IL-1 RtI in uterine oviduct during the peri-implantation period. We found that both IL-1 and its receptor were expressed in uterine tissues before and after ovulation (in the pre-ovulatory stage, even before the yolk had formed in the ovary). However, while IL-1alpha was mostly localized in the uterine mesenchyme tissue, IL-1beta and IL-1RtI were present in the uterine epithelium. Our data provide a further comparison between the reproduction of mammals and squamate reptiles.
Romagnoli
Roberta
R
Department of Physiology, University of Siena, 53100 Siena, Italy. romagnolir@unisi.it
Cateni
Chiara
C
Guarino
Fabio M
FM
Bigliardi
Elisa
E
Paulesu
Luana Ricci
LR
D000818:Animals; D004848:Epithelium / Q000737:chemistry; D005260:Female; D007375:Interleukin-1 / Q000032:analysis / Q000502:physiology*; D008116:Lizards / Q000502:physiology*; D008648:Mesoderm / Q000737:chemistry; D010060:Ovulation / Q000502:physiology*; D017472:Receptors, Interleukin-1 / Q000032:analysis; D013045:Species Specificity; D014599:Uterus / Q000737:chemistry; D014818:Vitellogenesis / Q000502:physiology
D007375:Interleukin-1; D017472:Receptors, Interleukin-1