Thrombocytopenia in Kawasaki disease: a risk factor for the development of coronary artery aneurysms.
The authors report on a 2-year-old boy with atypical Kawasaki disease (KD) and thrombocytopenia who developed 3 coronary artery aneurysms. The mechanism of thrombocytopenia in KD seems to be consumption coagulopathy. Review of the 30 reported cases of KD and thrombocytopenia revealed that this combination is more common in girls and in young age groups, and is associated with an increased risk of coronary artery aneurysm and myocardial infarction.
Department of Pediatrics, Schneider Children's Medical Center of Israel, Beilinson Campus, Petah Tiqva, Israel.
Yehuda
Y
Nofech-Mozes
Ben-Zion
BZ
Garty
D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D012307:Risk Factors; D013921:Thrombocytopenia / Q000150:complications*