The morphological and functional basis of the new conception about the suprarenal cortex regeneration.
The exhaustion of main intracellular and cellular reserves of the regeneration in suprarenal cortex under the influence of exogenous hyperthermia activates the supplementary sources of cellular regeneration. First type of low differentiated cortical cells appears under the outer connective tissue capsule on approximately the 7(th) day of hyperthermia. These cells proliferate and some of them migrate along the cortical blood capillaries towards the deep portion of zona fasciculate. They differentiate into the typical cortical cells (spongiocytes) of zona glomerulosa and zona fasciculate according to their location. Second type of low differentiated cortical cells appears through one circadian-septal period (during 7 days) near the inner connective tissue capsule that separate cortex from the medulla. This cell type gradually differentiates into the typical cortical cells of zona reticularis. Stem cortical cells were found in suprarenal cortex. They did not have specific morphological signs and could synthesize nucleus DNA.
Department of Histology, Crimea State Medical University of S. I. Georgievsky, 95006 APK Simferopol, Lenina bulv. 5/7, Ukraine.
Nadezhda K
NK
Kashirina
D000302:Adrenal Cortex / Q000166:cytology* / Q000378:metabolism / Q000502:physiology*; D000313:Adrenal Medulla / Q000166:cytology; D000818:Animals; D001345:Autoradiography; D002465:Cell Movement; D002467:Cell Nucleus / Q000378:metabolism; D005334:Fever / Q000473:pathology / Q000503:physiopathology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D012313:RNA / Q000096:biosynthesis; D012038:Regeneration / Q000502:physiology; D013234:Stem Cells / Q000166:cytology; D013997:Time Factors; D015383:Zona Fasciculata / Q000166:cytology; D015384:Zona Glomerulosa / Q000166:cytology; D015385:Zona Reticularis / Q000166:cytology
D012313:RNA