Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma.
Blue nevi (BN) and neurocristic hamartomas (NCH) are pigmented lesions that originate from the aberrant development of cells derived from the neural crest. BN are composed of dermal melanocytes, whereas NCH have a broader histology and show Schwann cell differentiation as well. In addition, BN and NCH might differ in their potential to develop into a malignancy. We describe a patient with a lesion showing features of both a plaque-type BN and NCH.
Department of Dermatology, Boston University, USA.
Caroline
C
Bevona
Zeina
Z
Tannous
Hensin
H
Tsao
D000328:Adult; D002455:Cell Division; D005260:Female; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D008544:Melanocytes / Q000473:pathology*; D018329:Nevus, Blue / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*