Comparison of gallium-67 citrate and technetium-99m tetrofosmin scan to detect Hodgkin's disease.
OBJECTIVE
The purpose of this study was to compare the usefulness of gallium-67 citrate (67Ga) and technetium-99m tetrofosmin (Tc-TF) scan to detect Hodgkin's disease (HD).


METHODS
In this study, 24 patients with HD underwent 67Ga and Tc-TF scan before receiving any therapy.


RESULTS
67Ga scan could detect HD in all 24 (100%) patients. Tc-TF scan could detect HD in 22/24 (91.6%) patients, but it was false-negative in one case of infradiaphragmatic HD and in another case with chemotherapy resistance. There was no significant difference in detection sensitivity between 67Ga and Tc-TF scan.


CONCLUSIONS
We conclude that Tc-TF scan can not replace conventional 67Ga scan to detect HD.
Department of Nuclear Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
Feng-Yuan
FY
Liu
Yu-Chien
YC
Shiau
Ruoh-Fang
RF
Yen
Jhi-Joung
JJ
Wang
Shung-Tai
ST
Ho
Chia-Hung
CH
Kao
D000328:Adult; D000367:Age Factors; D002951:Citrates; D005188:False Negative Reactions; D005260:Female; D005708:Gallium; D006689:Hodgkin Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012737:Sex Factors; D014915:Whole-Body Counting / Q000379:methods*
D002951:Citrates; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D005708:Gallium; C103850:gallium citrate