Mechanisms of action of intravenous immunoglobulin in autoimmune and inflammatory diseases.
Intravenous immunoglobulins (IVIg) exert a broad range of immunoregulatory functions that provide a basis for the beneficial effects of IVIg in autoimmune and systemic inflammatory disorders. This review focuses on the effects f IVIg on humoral and cellular immunity that may be of relevance for the treatment of inflammatory neurological diseases.
INSERM U430 and Université Pierre et Marie Curie, Institut des Cordeliers, Paris.
J
J
Bayry
M
M
Thirion
N
N
Misra
N
N
Thorenoor
S
S
Delignat
S
S
Lacroix-Desmazes
B
B
Bellon
S
S
Kaveri
M D
MD
Kazatchkine
D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000494:pharmacology / Q000627:therapeutic use*; D007249:Inflammation / Q000188:drug therapy
D016756:Immunoglobulins, Intravenous