Measurement of dopamine receptor-mediated jaw movements by a magnet-sensing system in freely moving rats.
This study tested a system for monitoring jaw movements in freely moving rats. A Hall-effect transducer was fixed to the skull in order to sense voltage changes induced by variations in the position of a magnet fixed to the mandible. By measuring dopamine receptor-mediated jaw movements, this system produces data comparable to that obtained using a light-sensitive transducer system in anesthetized rats, while also measuring the vertical component of jaw movements in freely moving rats. In combination with conventional visual observation, this system may provide a useful tool for assessing movements of the orofacial region during spontaneous and drug-evoked behavior.
Lee
J
J
Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Adachi
K
K
Gionhaku
N
N
Fujita
S
S
Uchida
T
T
Koshikawa
N
N
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D018491:Dopamine Agonists / Q000494:pharmacology*; D004867:Equipment Design; D007568:Jaw / Q000187:drug effects / Q000502:physiology*; D008027:Light; D008280:Magnetics; D008991:Monitoring, Physiologic / Q000295:instrumentation; D009068:Movement / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*; D014159:Transducers
D018491:Dopamine Agonists; D011954:Receptors, Dopamine; D001058:Apomorphine