Hot and cold in Drosophila larvae.
Temperature is one of our most important physical cues, with extremes eliciting painful sensory warnings of tissue damage. Two recent publications present findings in Drosophila that implicate different neural substrates for low- and high-temperature responses, as well as indicating that a transient receptor potential (TRP) channel family member, painless, plays a role in these responses.
Zars
Troy
T
University of Missouri-Columbia, Division of Biological Sciences, 114 Lefevre Hall, Columbia, MO 65211, USA. zarst@missouri.edu
D000222:Adaptation, Physiological; D000818:Animals; D001833:Body Temperature Regulation / Q000502:physiology*; D004330:Drosophila / Q000378:metabolism*; D029721:Drosophila Proteins / Q000378:metabolism*; D007473:Ion Channels / Q000378:metabolism*; D007814:Larva / Q000378:metabolism; D051379:Mice; D009474:Neurons / Q000502:physiology; D013697:Thermosensing / Q000502:physiology*
D029721:Drosophila Proteins; D007473:Ion Channels; C474592:pain protein, Drosophila