[Antibiotic prophylaxis in limited gynecological surgeries for pregnancy termination].
The authors attempted with this trial to confirm the necessity of periabortal antibiotic prophylaxis after spontaneous and induced abortion. The trial included 172 patients with abortion; 53 of them with induced abortion and 119 with spontaneous abortion. The term of gestation was between 5 and 22 week. Three therapeutic groups were compared to a control no-treatment group. The first group was given Ampicillin orally 4 x 500 mg for 5 consecutive days. The second group was administered a combination of Ampicillin orally 4 x 500 mg plus Gentamycin 2 x 80 mg i.m. for 3 to 5 days postoperatively. The third group was given 3 x 2 g i.v. Cefazolin intraoperatively and 24 hours following the manipulation. The trial aimed at establishing the efficiency and cost-effectiveness of the antibiotic prophylaxis. The results tend to prove the perioperative prophylaxis with Cefazolin is preferable since it is most efficient and cost-effective.
Nalbanski
B
B
Maternity University Hospital Maichin dom, Sofia.
Tsekova
K
K
Ivanov
S
S
D000028:Abortion, Induced; D000667:Ampicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001424:Bacterial Infections / Q000517:prevention & control*; D002437:Cefazolin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D016896:Treatment Outcome
D005839:Gentamicins; D000667:Ampicillin; D002437:Cefazolin