Weber-Christian disease presenting with ocular manifestations.
A Japanese patient with Weber-Christian disease (WCD) presenting with ocular symptoms is reported. Panniculitis in the retrobulbar fat was diagnosed according to the histological findings from biopsy specimens, and improved over a month under steroid administration. Only three patients showing ocular manifestations have previously been reported. Panniculitis was in the late stage and a medium dose of prednisolone was effective in this patient. A biopsy of the orbital fat was useful for diagnosis. However, it is important to recognise that the stage of inflammation varies according to the fat tissue involved by WCD.
Yoshida
T
T
Kochi Medical School, Kochi, Japan.
Ito
H
H
Matsubara
Y
Y
Kitamura
Y
Y
Sasaoka
A
A
Chijiwa
T
T
Hashimoto
K
K
Komatsu
T
T
Moriki
T
T
Itahara
T
T
D000368:Aged; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D015434:Panniculitis / Q000175:diagnosis*; D010201:Panniculitis, Nodular Nonsuppurative / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D011239:Prednisolone