[Indications for surgical treatment of Parkinson's disease and outcome].
There is no single opinion about the indications and best method of surgical treatment of Parkinson's disease. We presented the most common indications for surgery and evaluated the results of stereothalamotomies and stereopallidotomies, performed in our clinic, analyzed their effectiveness on the main motor symptoms of parkinsonism. During the last 29 years we performed 219 thalamotomies (45 bilateral) and 131 pallidotomies (23 bilateral) on 279 patients. Pallidotomy of the same side was repeated for 3 patients to correct the size of too small destruction and shortlasting effect. Good effect for parkinsonian tremor was achieved in 89.54% of patients after thalamotomies and in 77.42% after pallidotomies; for rigidity in 84.4% after thalamotomies and 83.15% after pallidotomies; for hypokinesia in 55% after pallidotomies and 6.5% after thalamotomies. In both types of operations the best effect was observed on the controlateral side. Bilateral effect (less on the ipsilateral side) was present in 5.17% of unilateral thalamotomies and in 14.28% of pallidotomies.
Sidiskis
Juozas
J
Clinic of Neurosurgery, Kaunas University of Medicine, Eiveniu 2, 3007 Kaunas, Lithuania.
D001921:Brain / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D005917:Globus Pallidus / Q000601:surgery; D006801:Humans; D010300:Parkinson Disease / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome