Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model.
BACKGROUND
This study aimed to establish the accuracy and reproducibility of localization of intraluminal markers by laparoscopic and open techniques in a swine colorectal model, using a prototype for a novel wireless system.


METHODS
A prototype marker was placed into the colon of an adult pig. The surgeon was blinded to placement and localized the marker using a detection probe (3 surgeons/10 trials/2-D and 3-D systems).


RESULTS
Each surgeon was able to accurately locate the marker within 28.7 +/- 20.6 (LAP) and 18.3 +/- 6.7 (OPEN) sec ( p = 0.013). There were no significant differences between surgeons in localization times, regardless of experience. A 3-D interface made no difference in accuracy or time (LAP = 35 vs 28 seconds; p = NS [not significant]).


CONCLUSIONS
This study demonstrates the use of a novel system for intraoperative identification of nonpalpable lesions. This technology may have important implications in the surgical management of nonpalpable tumors and in applications of interventional radiology.
Sonnenday
C J
CJ
Department of Surgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Kaufman
H S
HS
D000818:Animals; D003106:Colon / Q000601:surgery*; D012809:Colon, Sigmoid / Q000601:surgery; D015179:Colorectal Neoplasms / Q000601:surgery*; D004867:Equipment Design; D021621:Imaging, Three-Dimensional; D020007:Implants, Experimental; D007430:Intraoperative Care; D010535:Laparoscopy / Q000379:methods*; D008280:Magnetics; D023421:Models, Animal; D010865:Pilot Projects; D012007:Rectum / Q000601:surgery; D015203:Reproducibility of Results; D013552:Swine; D013997:Time Factors; D014584:User-Computer Interface