Infection-associated hemophagocytic syndrome in a diabetic patient undergoing chronic hemodialysis.
Hemophagocytic syndrome (HPS) is an uncommon but severe illness associated with a variety of infections, malignant tumors, and autoimmune diseases. We report a case of infection-associated HPS in a patient receiving chronic hemodialysis. Peptostreptococcus-induced sepsis and abscess formation in the left iliopsoas muscle led to the onset of infection-associated HPS in this patient. The patient had diabetes mellitus and end-stage renal disease, and it is likely that immunological dysfunctions from these disorders played a part in the onset of both severe bacterial infections and HPS.
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. rasenami@poppy.ocn.ne.jp
Yoko
Y
Wada
Maki
M
Sato
Akihiko
A
Saito
Fumitake
F
Gejyo
D000368:Aged; D003920:Diabetes Mellitus / Q000503:physiopathology*; D017809:Fatal Outcome; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D008297:Male; D016659:Psoas Abscess / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D006435:Renal Dialysis / Q000009:adverse effects*; D013291:Streptococcus