Stereocontrolled reactions mediated by a remote sulfoxide group: synthesis of optically pure anti-beta-amino alcohols.
[reaction: see text] A one-step synthesis of enantiomerically pure anti-1,2-amino alcohol derivatives has been achieved by reaction of prochiral oxygenated 2-p-tolylsulfinylbenzyl carbanions with N-sulfinylimines bearing the same configuration at sulfur.
García Ruano
José L
JL
Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049-Madrid, Spain. joseluis.garcia.ruano@uam.es
Alemán
José
J