Longterm survival after surgical removal of solitary brain metastasis from osteosarcoma.
The prognosis of osteosarcoma with brain metastasis is very poor. We report a 14-year-old girl with osteosarcoma of the right distal femur who is alive and free of disease 6 years after the craniotomy and irradiation for brain metastasis. This longterm survival is attributed to the absence of active pulmonary metastasis at the onset of brain metastasis and the complete removal of the brain metastasis by craniotomy. Patients without active pulmonary metastasis at the onset of brain metastasis may achieve longterm survival. In such patients, it would be worthwhile to perform craniotomy aggressively.
Division of Orthopaedic Surgery, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan. tyonemot@chiba-cc.pref.chiba.jp
Tsukasa
T
Yonemoto
Shin-Ichiro
S
Tatezaki
Takeshi
T
Ishii
Katsunobu
K
Osato
Toshinao
T
Takenouchi
D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D012516:Osteosarcoma / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery*