Sphincterotomy in patients with gallstones, elevated LFTs and a normal CBD on ERCP.
OBJECTIVE
To determine whether an endoscopic sphincterotomy affects outcome in patients with symptomatic gallstones, elevated liver function tests and a normal common bile duct on endoscopic retrograde cholangiopancreatogram.


METHODS
A total of 163 patients with symptomatic gallstones and elevated liver function tests, and found to have a normal common bile duct on endoscopic retrograde cholangiopancreatogram were included in the study. Endoscopic sphincterotomy was performed in 78 (47.8%) patients, while 85 (52.1%) patients did not have an endoscopic sphincterotomy. The two groups were compared for detection of small unseen common bile duct stones/debris, endoscopic retrograde cholangiopancreatogram related complications, and biliary complications after cholecystectomy.


RESULTS
Small common bile duct stones/debris were recovered in 11/43 (25.5%) patients who had instrumentation of the common bile duct performed after endoscopic sphincterotomy. Common bile duct instrumentation was not performed in any of the patients without endoscopic sphincterotomy. No patient had any biliary complication after cholecystectomy, both in the immediate postoperative period and on a follow-up of 37.5 +/- 13.6 months (range 17-66). Endoscopic retrograde cholangiopancreatogram related complications occurred in 8 patients who had an endoscopic sphincterotomy and in 2 without endoscopic sphincterotomy (p < 0.05).


CONCLUSIONS
Performing an endoscopic sphincterotomy in these patients increases the detection of small unseen common bile duct stones/debris without changing the clinical outcome after cholecystectomy. It also increases the endoscopic retrograde cholangiopancreatogram related complication rate, and therefore may not be necessary.
Department of Medicine, Faculty of Medicine, Kuwait University, Thuniyan Al-Ghanim Gastroenterology Center, Al-Amiri Hospital, Kuwait. isiddique@hsc.kuniv.edu.kw
Iqbal
I
Siddique
Krishna
K
Mohan
Abdulkareem
A
Khajah
Fuad
F
Hasan
Anjum
A
Memon
Maher
M
Kalaoui
Mohammad
M
al-Shamali
Istvan
I
Patty
Basil
B
al-Nakib
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002760:Cholangiopancreatography, Endoscopic Retrograde; D005260:Female; D042882:Gallstones / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D016717:Sphincterotomy, Endoscopic; D016896:Treatment Outcome