Outcome of macular hole surgery.
OBJECTIVE
To document the outcome of macular hole surgery in terms of improvement of visual acuity and the duration of closure of macular hole.


METHODS
Interventional quasi experimental study.


METHODS
Ophthalmology Department, Civil Hospital, Karachi.


METHODS
Twenty-four eyes of 22 patients with macular hole underwent surgical repair. Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange followed by prone positioning for one to two weeks was carried out. Postoperative follow-up was done for one year. Main outcome measures were visual acuity, closure of macular hole and ocular complications. Data was analyzed by using SPSS Version 10. Non-parametric sign test with chi-square statistic was used to compare the pre-operative and postoperative outcome.


RESULTS
The macular hole was successfully closed in 17 eyes that revealed high statistical significance regarding improvement in visual acuity. Earlier, significant improvement figured in 17/24 cases was observed at three-month post-operative examination (p<0.0001). An insignificant success figured in 8/24 due to postoperative complications at six-month follow-up. Visual acuity improved upto two or more lines in 17 eyes at one-year follow-up. Twelve cases developed cataract, 7 developed increased intra-ocular pressure (transient), one had glaucoma and one retinal detachment.


CONCLUSIONS
Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange can successfully close macular holes and improve vision.
Khokhar
Abdur Rasheed
AR
Department of Ophthalmology, Dow Medical College and Civil Hospital, Karachi.
Faiz-ur-Rab
Khowaja
K
Akhtar
Hafiz Usman
HU
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy