Sleep attacks in Parkinson's disease: a clinical and polysomnographic study.
The objective of the study was to evaluate daytime sleepiness, (the features of episodes of sudden sleep onset), i. e., so-called sleep attacks (SAs), in three male Parkinson's disease (PD) patients (mean age 66 years) on chronic therapy with ropirinole or pramipexole. A structured clinical interview, the Epworth Sleepiness Scale, and continuous 24-h ambulatory polysomnography were used to assess the features of SAs occurring in the patients in their normal home environments. The polysomnographic patterns characterizing SAs (sleep occurring against a background of wakefulness, and not preceded by a feeling of sleepiness or by other heralding symptoms) were analyzed. The results showed that SAs can be clearly documented through polysomnographic monitoring and really, but rarely, occur in PD. SAs seem to represent the extreme of the continuum of daytime sleepiness observed in PD patients.
Unit of Parkinson's Disease and Movement Disorders, Institute of Neurology, IRCCS C. Mondino Foundation, Pavia, Italy.
C
C
Pacchetti
E
E
Martignoni
M
M
Terzaghi
R
R
Zangaglia
F
F
Mancini
G
G
Nappi
R
R
Manni
D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use; D006970:Disorders of Excessive Somnolence / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy; D017286:Polysomnography / Q000379:methods*; D012894:Sleep Stages / Q000502:physiology
D000978:Antiparkinson Agents