Smoking is a risk factor for multiple sclerosis.
The authors determined the relationship between tobacco smoking and the risk of developing multiple sclerosis (MS) in a general population of 22,312 individuals living in Hordaland, Norway in 1997. A total of 87 individuals reported having developed MS. The risk of MS was higher among smokers than among never-smokers (rate ratio 1.81, 95% CI 1.1 to 2.9; p = 0.014). Studies on how smoking interacts with disease onset may contribute to determining the causal agents of this disease.
Department of Public Health and Primary Health Care, Section of Occupational Medicine, University of Bergen, Norway. trond.riise@isf.uib.no
Trond
T
Riise
Monica W
MW
Nortvedt
Alberto
A
Ascherio
D000328:Adult; D017668:Age of Onset; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology*; D009664:Norway / Q000453:epidemiology; D016017:Odds Ratio; D015995:Prevalence; D016016:Proportional Hazards Models; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*; D011795:Surveys and Questionnaires