A case of mixed connective tissue disease showing a lymphoid follicle in muscle pathology.
We report a 74-year-old man suffering from mixed connective tissue disease (MCTD) accompanied by a lymphoid follicle in muscle pathology. He showed proximal muscle weakness and arthritis in finger joints. His laboratory findings were characteristic of MCTD. Prednisolone administration favorably improved his symptoms. A lymphoid follicle is a rare pathological finding in inflammatory myopathies. The immunohistochemical findings suggest that the lymphoid follicle would be involved in the specific role for the pathogenesis of MCTD.
Inoue
Chieko
C
Department of Neurology, Gunma University School of Medicine, 3-39-22 Showa-machi, 371-8511 Maebashi, Japan.
Ikeda
Yoshio
Y
Tanaka
Makoto
M
Sakazume
Yuka
Y
Okamoto
Koichi
K
D000368:Aged; D006801:Humans; D008221:Lymphoid Tissue / Q000473:pathology*; D008297:Male; D008947:Mixed Connective Tissue Disease / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology*