New boronic acid fluorescent reporter compounds. 2. A naphthalene-based on-off sensor functional at physiological pH.
[structure: see text] A new boronic acid fluorescent on-off reporter compound (1) was synthesized. This fluorescent sensor shows a 41-fold emission intensity increase upon addition of 50 mM fructose in 0.1 M aqueous phosphate buffer at pH 7.4.
Gao
Xingming
X
Department of Chemistry, Georgia State University, 33 Gilmer Street S.E., Atlanta, Georgia 30303, USA.
Zhang
Yanling
Y
Wang
Binghe
B
D015057:1-Naphthylamine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D001895:Boron / Q000737:chemistry; D001897:Boronic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D017186:Titrimetry
C485394:4-(dimethylamino)naphthalene-1-boronic acid; D001897:Boronic Acids; D002241:Carbohydrates; D009281:Naphthalenes; C031721:naphthalene; D015057:1-Naphthylamine; D001895:Boron