Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the Venestent study.
The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vessel revascularization rate was 31.4% vs. 14.5% (P < 0.05), and event-free survival was 60.0% vs. 76.3% (P < 0.05) for the balloon and stent group, respectively. Elective stent implantation in de novo SVG lesions is associated with a significant lower target vessel revascularization rate and a significant higher event-free survival at 1-year follow-up as compared to balloon angioplasty.
Hanekamp
Clara E E
CE
Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Koolen
Jacques J
JJ
Den Heijer
Peter
P
Schalij
Martin J
MJ
Piek
Jan J
JJ
Bär
Frits W H M
FW
De Scheerder
Iwan
I
Bonnier
Hans J R M
HJ
Pijls
Nico H J
NH
D000368:Aged; D000800:Angioplasty, Balloon; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003327:Coronary Disease / Q000601:surgery; D005260:Female; D006083:Graft Occlusion, Vascular / Q000628:therapy*; D006801:Humans; D008297:Male; D012501:Saphenous Vein / Q000637:transplantation; D015607:Stents; D016896:Treatment Outcome