title: Prions and disposable surgical instruments.
abstract: Single-use surgical instruments have been used in the UK's ENT departments. This is in response to guidelines issued by the Department of Health and the British Association of Otolaryngologists and Head and Neck Surgeons, in order to prevent the spread of new variant Creutzfeldt-Jakob disease (vCJD) in a young population of patients undergoing routine adenotonsillectomy. In one institution we found that the new single-use instruments were inferior to previous standard kits and that postoperative haemorrhage rates had increased following children's tonsillectomy from 1.7% to 7.8% (p<0.01). Because of the increased reporting of complications following the use of single-use surgical instruments for adenotonsillectomies, ENT departments in the UK are no longer obliged to use these disposable instruments. This is due to the theoretical risk of prion infection being outweighed by the actual risk to the patient from increased postoperative haemorrhage.
authors: Department of Otolaryngology, Hull Royal Infirmary, Hull, UK.
authors: P
authors: P
authors: Nix
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D007562:Creutzfeldt-Jakob Syndrome / Q000635:transmission*; D004209:Disposable Equipment / Q000382:microbiology*; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D011328:Prions / Q000472:pathogenicity; D012189:Retrospective Studies; D013525:Surgical Instruments; D014068:Tonsillectomy / Q000009:adverse effects* / Q000295:instrumentation
chemical_list: D011328:Prions