The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer.
The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer (n=73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific survival, independent of grade, in this cohort.
Bromwich
E J
EJ
Department of Urology, Gartnavel General Hospital, Glasgow G12 0YN, UK. d.c.mcmillan@clinmed.gla.ac.uk
McArdle
P A
PA
Canna
K
K
McMillan
D C
DC
McNicol
A-M
AM
Brown
M
M
Aitchison
M
M
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000276:immunology* / Q000473:pathology* / Q000601:surgery; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000276:immunology* / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016019:Survival Analysis; D013601:T-Lymphocytes / Q000276:immunology*; D016896:Treatment Outcome