title: A novel method for insertion of post-pyloric feeding tubes at the bedside without endoscopic or fluoroscopic assistance: a prospective study.
abstract: OBJECTIVE
  To assess a novel method, adapted from already published literature, for bedside placement of nasojejunal feeding tubes using erythromycin, air insufflation of the stomach and continuous ECG guidance.
  
  
  METHODS
  Prospective study in a tertiary teaching hospital.
  
  
  METHODS
  40 consecutive patients who required enteral nutrition and mechanical ventilation for at least 48 h.
  
  
  METHODS
  Erythromycin (200 mg) was administered intravenously 30 min prior to the insertion of the feeding tube. The post-pyloric feeding tube was then inserted into the stomach and 500 ml air insufflated. Stomach ECG was performed, and during further insertion of the tube the QRS complex was continuously monitored for a change in polarity, suggesting passage across the midline through the pylorus. At the end of the procedure aspirate was obtained from the feeding tube and checked for alkaline pH. Exact tube position was determined by abdominal radiography.
  
  
  RESULTS
  In 88% of cases the feeding tubes were post-pyloric, with a median time to insertion of 15 min (range 7-75). No major complications were seen in 52 attempts. Change in QRS polarity had 94% sensitivity in predicting post-pyloric tip placement. Of the 32 alkaline pH aspirates 31 were post-pyloric.
  
  
  CONCLUSIONS
  This procedure is safe, effective and could be performed in a short time period within the confines of the intensive care unit without endoscopic assistance.
authors: Department of Anaesthesiology, General Hospital De Heel, Zaans Medical Center, P.O. Box 210, 1500 EE Zaandam, The Netherlands. slagt.c@deheel.nl
authors: Cornelis
authors: C
authors: Slagt
authors: Richard
authors: R
authors: Innes
authors: David
authors: D
authors: Bihari
authors: John
authors: J
authors: Lawrence
authors: Yahya
authors: Y
authors: Shehabi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis / Q000379:methods*; D003422:Critical Care / Q000379:methods; D004562:Electrocardiography / Q000379:methods* / Q000592:standards; D016099:Endoscopy, Gastrointestinal; D004750:Enteral Nutrition; D004917:Erythromycin / Q000627:therapeutic use*; D005260:Female; D005471:Fluoroscopy; D005745:Gastric Acidity Determination; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007327:Insufflation / Q000379:methods* / Q000592:standards; D007441:Intubation, Gastrointestinal / Q000379:methods* / Q000592:standards; D007583:Jejunum; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods / Q000592:standards; D019095:Point-of-Care Systems; D011446:Prospective Studies; D012449:Safety; D012680:Sensitivity and Specificity; D013396:Suction; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D004917:Erythromycin