Hydrolysis triggers oxidation of a trans diamine platinum(II) anticancer complex.
Pizarro
Ana María
AM
Facultad de Ciencias, Departamento de Química Inorgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.
Munk
Vivienne P
VP
Navarro-Ranninger
Carmen
C
Sadler
Peter J
PJ
D000970:Antineoplastic Agents / Q000737:chemistry*; D002082:Butylamines / Q000138:chemical synthesis / Q000737:chemistry*; D002945:Cisplatin / Q000138:chemical synthesis / Q000737:chemistry*; D015195:Drug Design; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D009944:Organoplatinum Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D021241:Spectrometry, Mass, Electrospray Ionization; D013237:Stereoisomerism
D000970:Antineoplastic Agents; D002082:Butylamines; D009944:Organoplatinum Compounds; C034697:transplatin; D002945:Cisplatin