[Visceral leishmaniasis in children: prognostic factors].
The morbidity and death rate of visceral leishmaniasis (VL) is important. The aim of our study is to find prognosis factors of VL. Two hundred and thirty two children with VL were retrospectively studied. These children were followed in Rabta and Kairouan hospitals between 1985 and 1998. We identify 7 prognosis factors, at the hospital admission, visit delayed more than 56 days, fever during more than 21 days, normal or low temperature, haemorrhagic syndrome hemoglobin rate < 5.5 g/dl, sedimentation rate < 25 mm and hypoalbuminaemia < 30 g/l. The presence of one prognosis factors or more appears to consider amphotericin B as a first-line treatment.
Abdelmoula
Mohamed Slim
MS
Service de Pédiatrie EPS la Rabta, Tunis.
M'Hamdi
Zohra
Z
Amri
Fethi
F
Tebib
Néji
N
Ben Turkia
Hadhami
H
Ben Dridi
Marie Françoise
MF
D000666:Amphotericin B / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001799:Blood Sedimentation; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever; D006470:Hemorrhage; D006801:Humans; D034141:Hypoalbuminemia; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors
D000981:Antiprotozoal Agents; D000666:Amphotericin B