title: Non-convulsive status epilepticus associated with tiagabine therapy in children.
abstract: A case of a 7-year-old male with epilepsy who developed non-convulsive status epilepticus (NCSE) with electroclinical features consistent with those of atypical absence seizures after adjunctive antiepileptic therapy of tiagabine (TGB) is reported. The patient had frequent generalised and rare partial seizures with generalised epileptic discharges on prior electroencephalogram (EEG) recordings. NCSE was developed when rapid dosage increase and high dose of TGB was given. This case emphasises the need for close monitoring of children with epilepsy taking TGB for exacerbation of seizures or development of NCSE.
authors: Second Department of Paediatrics-University of Athens, P & A Kyriakou Children's Hospital, Athens, Greece.
authors: Angeliki
authors: A
authors: Skardoutsou
authors: Konstantinos A
authors: KA
authors: Voudris
authors: Eleni A
authors: EA
authors: Vagiakou
mesh_terms: D002648:Child; D004569:Electroencephalography / Q000379:methods; D006801:Humans; D008297:Male; D009557:Nipecotic Acids / Q000009:adverse effects*; D013226:Status Epilepticus / Q000139:chemically induced* / Q000503:physiopathology; D000078308:Tiagabine
chemical_list: D009557:Nipecotic Acids; D000078308:Tiagabine