title: Surveillance of Haemophilus influenzae among respiratory tract samples of Turkish children.
abstract: We conducted three prospective studies of Haemophilus influenzae in different groups of children. Pharyngeal swab samples were taken (i). from 1382 healthy infants and children between 0 and 10 years of age (group 1), attending well child clinics (n=438), day care centres (n=440) and elementary schools (n=504), and (ii). from 322 children aged 2-10 years (group 2), clinically diagnosed as having upper respiratory tract infection. Pharyngeal swab samples and sinus aspirates were obtained from 49 children between 2 and 9 years of age (group 3), clinically diagnosed as having sinusitis. H. influenzae was isolated in similar rates from 315 (22.7%) of children in group 1, 72 (22.3%) of children in group 2 and 12 (24.4%) of children in group 3. Serotype b comprised 7, 5.2 and 2% of all H. influenzae isolates for group 1, 2 and 3, respectively. Production of beta-lactamase was detected in 1.0% of H. influenzae type b isolates in group 1, 1.2 and 6.1% of all isolates in group 2 and 3, respectively. There were no beta-lactamase negative ampicillin-resistant strains.
authors: Department of Clinical Microbiology, Marmara University School of Medicine, Haydarpasa, Istanbul, Turkey.
authors: Aysegul
authors: A
authors: Yagci
authors: Arzu
authors: A
authors: Ilki
authors: Cengiz
authors: C
authors: Akbenlioglu
authors: Nurver
authors: N
authors: Ulger
authors: Selcuk
authors: S
authors: Inanli
authors: Güner
authors: G
authors: Söyletir
authors: Mustafa
authors: M
authors: Bakir
mesh_terms: D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D006192:Haemophilus Infections / Q000453:epidemiology / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D010614:Pharynx / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000382:microbiology*; D014421:Turkey / Q000453:epidemiology; D018440:beta-Lactam Resistance / Q000502:physiology*; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases