Effect of high-pressure helium on latex-induced activated chemiluminescence of human blood leucocytes.
High-pressure helium reduces the latex-induced activated chemiluminescence of diluted human blood. This effect is more noticeable, when lucigenin rather than luminol is used as the activator of chemiluminescence. The effect lessens in the presence of Mg2+ but not Ca2+. The data suggest the association of this effect with actin polymerization in leucocytes phagocytosing the latex particles.
Tyurin-Kuz'min
A Yu
AY
Department of Hyperbaric Physiology, Shirshov Institute of Oceanology, Russian Academy of Sciences, Moscow 117851, Russia. marina@ocean.ru
Vdovin
A V
AV
D006371:Helium / Q000737:chemistry*; D006801:Humans; D007477:Ions / Q000737:chemistry; D007840:Latex / Q000494:pharmacology*; D007962:Leukocytes / Q000187:drug effects* / Q000378:metabolism*; D008163:Luminescent Measurements; D011312:Pressure
D007477:Ions; D007840:Latex; D006371:Helium