title: The effects of cycle racing on pulmonary diffusion capacity and left ventricular systolic function.
abstract: The purpose of this study was to examine the effects of a 20 km cycle race (TT) on left ventricular (LV) systolic and pulmonary function in 12 endurance cyclists. Spirometry, single-breath diffusion capacity (DLCO) with partitioning of membrane (DM) and capillary blood volume (Vc) components and 2-D echocardiograms were performed before and after the TT. During the TT mean oxygen consumption was 3.79 +/- 0.5 L x min(-1) (83 +/- 5.5% of VO2max) and mean blood lactate was 8.4 +/- 2.4 mM. Following the TT, spirometry values were unchanged, however, DLCO and DM were significantly (P<0.05) reduced. LV systolic function was increased (P<0.05) immediately after exercise, while end-diastolic area was decreased (P<0.05) at all points during recovery. The reduction in DM was correlated with LV systolic function following the TT. This relationship suggests a cardiovascular contribution to pulmonary diffusion impairment following exercise.
authors: Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Alta., Canada T6G 2H9.
authors: Michael K
authors: MK
authors: Stickland
authors: Stewart R
authors: SR
authors: Petersen
authors: Mark J
authors: MJ
authors: Haykowsky
authors: Dylan A
authors: DA
authors: Taylor
authors: Richard L
authors: RL
authors: Jones
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology; D003198:Computer Simulation; D004452:Echocardiography / Q000379:methods; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test / Q000379:methods; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology; D011653:Pulmonary Diffusing Capacity / Q000502:physiology*; D013147:Spirometry / Q000379:methods; D013312:Stress, Physiological; D013599:Systole / Q000502:physiology*; D013997:Time Factors; D016277:Ventricular Function, Left / Q000502:physiology*