title: Treatment of severe neuroleptic-induced tardive torticollis.
abstract: BACKGROUND: The aim of this paper is to describe a case of severe neuroleptic-induced tardive torticollis successfully treated with a combination of clozapine, clonazepam and botulinum toxin-A. CASE REPORT: The patient, a 30-year old man with a seven-year history of delusional disorder experienced severe right torticollis with painful tightness of the neck and elevation of the shoulder. At this time he was receiving haloperidol 20 mg, trifluoperazine 5 mg, zuclopenthixol 20 mg and biperidine 4 mg daily. The combination therapy with clozapine and clonazepam and the long-term use of botulinum toxin-A resulted in a complete remission of dystonic movements. CONCLUSIONS: The present observations provide evidence indicating that this combination therapy may be of benefit in patients with severe neuroleptic-induced tardive torticollis.
authors: Department of Psychiatry, University of Athens, Eginition Hospital, Athens, Greece. bkont@cc.uoa.gr
authors: Beata J
authors: BJ
authors: Havaki-Kontaxaki
authors: Vassilis P
authors: VP
authors: Kontaxakis
authors: Maria M
authors: MM
authors: Margariti
authors: Konstantinos G
authors: KG
authors: Paplos
authors: George N
authors: GN
authors: Christodoulou