title: Effects of weight reduction interventions by community pharmacists.
abstract: OBJECTIVE
  To compare a meal replacement (MR) program with a conventional reduced-calorie diet (RCD) for weight management using the pharmacy as the setting and the pharmacist as the point of contact for dietary advice.
  
  
  METHODS
  Randomized, controlled, open-label trial.
  
  
  METHODS
  Travis Pharmacy in Shenandoah, Iowa.
  
  
  METHODS
  Ninety-five patients from southwestern iowa and southeastern Nebraska were enrolled, of whom 88 were considered eligible for comparison (by continuing through week 2 of the study).
  
  
  METHODS
  Patients were randomized to an MR plan or a traditional RCD plan. Patients were followed for a 3-month period of active weight loss and a 10-week period of weight maintenance. Patients returned every 3 weeks for follow-up with the pharmacist, for a total of 13 visits.
  
  
  METHODS
  Weight changes.
  
  
  RESULTS
  During the active weight loss phase, the MR (n = 45) and RCD (n = 43) groups lost a significant amount of weight, although no significant difference was found between the groups (mean +/- standard error = 4.90 +/- 0.30 kg MR versus 4.30 +/- 0.30 kg RCD; P = .16). In the weight maintenance phase, the MR group lost 0.70 +/- 0.40 kg and the RCD group lost 0.90 +/- 0.40 kg (P = .60). Significant improvements were observed in waist circumference, systolic and diastolic blood pressure, and triglyceride levels. No significant changes were seen in high-density lipoprotein cholesterol or low-density lipoprotein cholesterol levels in either group.
  
  
  CONCLUSIONS
  Successful weight management can be achieved in a pharmacy setting. Both MR and RCD programs were effective.
authors: Bernard J. Dunn School of Pharmacy, Shenandoah University, 1460 University Drive, Winchester, VA 22601, USA. rahrens@su.edu
authors: Renee A
authors: RA
authors: Ahrens
authors: Matthew
authors: M
authors: Hower
authors: Al M
authors: AM
authors: Best
mesh_terms: D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003157:Community Pharmacy Services / Q000458:organization & administration*; D004038:Diet, Reducing; D005260:Female; D005526:Food, Formulated; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy*; D015431:Weight Loss
chemical_list: D002784:Cholesterol