title: Acute Marchiafava-Bignami disease: MR findings in two patients.
abstract: Marchiafava-Bignami is a rare toxic disease seen mostly in chronic alcoholics that results in progressive demyelination and necrosis of the corpus callosum. The process may extend laterally into the neighboring white matter and occasionally as far as the subcortical regions. We present the MR imaging findings in two patients who presented acutely and review the features of the disease and of other acute alcohol-related disorders.
authors: Department of Radiology, Instituto Neurologico de Antioquia, Medellin, Colombia, USA.
authors: Andres
authors: A
authors: Arbelaez
authors: Adriana
authors: A
authors: Pajon
authors: Mauricio
authors: M
authors: Castillo
mesh_terms: D000368:Aged; D000437:Alcoholism / Q000150:complications*; D001927:Brain Diseases / Q000175:diagnosis* / Q000209:etiology*; D002908:Chronic Disease; D003337:Corpus Callosum; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged