Adrenal neuroblastoma in an adult: report of a case.
Neuroblastomas comprise a major part of adrenal tumors in children. However, they are seldom reported in adults. In this report we present the case of a 30-year-old woman who was operated on for an incidentaloma. Following an adrenalectomy, she was put on a chemoradiotherapy regimen. A histopathologic assessment of the specimen revealed Homer-Wright rosettes against a background of fibrillary matrix, which indicated a diagnosis of a neuroblastoma. In spite of a low incidence in adulthood, it should be emphasized that all adrenal tumors without any particular characteristics may be a neuroblastoma, which tends to show a very poor prognosis. Hence, such patients should undergo postoperative chemoradiotherapy, which may improve both the remission rates and survival.
Genc
Fatih Ata
FA
Department of General Surgery, Medical Faculty of Istanbul University, 34390 Istanbul, Capa, Turkey.
Aksoy
Murat
M
Kapran
Yersu
Y
Tunca
Fatih
F
Tanakol
Refik
R
Basar
Yilmaz
Y
Terzioglu
Tarik
T
D000310:Adrenal Gland Neoplasms / Q000473:pathology* / Q000628:therapy*; D000315:Adrenalectomy / Q000379:methods; D000328:Adult; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000473:pathology* / Q000628:therapy*; D011182:Postoperative Care / Q000379:methods; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D016896:Treatment Outcome