Treatment of osteoarthritic cartilage lesions with osteochondral autograft transplantation.
Twenty-two osteochondral autograft transplantations were performed on two types of knees: those with isolated (group 1) and multiple (group 2) degenerative cartilage lesions. At minimum 24-month follow-up, group 1 had significantly better pain relief and function than group 2 based on the Western Ontario and McMaster Universities Osteoarthritis Index and pain scores (10-point visual analog scale). Osteochondral autograft transplantation may be effective in treating knees with isolated degenerative cartilage lesions but appears contraindicated in those with multiple lesions.
Andres
Brett M
BM
Johns Hopkins Bayview Medical Center, Baltimore, MD 21224-2780, USA.
Mears
Simon C
SC
Somel
Deniz S
DS
Klug
Ray
R
Wenz
James F
JF
D000368:Aged; D016025:Bone Transplantation / Q000379:methods*; D002358:Cartilage, Articular / Q000473:pathology / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy; D014182:Transplantation, Autologous; D016896:Treatment Outcome