title: Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.
abstract: From a myxomycete Arcyria ferruginea, dihydroarcyriarubin C (1), a new bisindole alkaloid, has been isolated together with two known bisindoles, arcyriarubin C (2) and arcyriaflavin C (3), and arcyriaflavin C (3) was also isolated from Tubifera casparyi together with arcyriaflavin B (4). Arcyriaflavin C (3) exhibited cell cycle inhibition effect at G1 and G2/M stage at 10 and 100ng/mL, respectively.
authors: Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
authors: Satomi
authors: S
authors: Nakatani
authors: Ayano
authors: A
authors: Naoe
authors: Yukinori
authors: Y
authors: Yamamoto
authors: Tomohiro
authors: T
authors: Yamauchi
authors: Naoto
authors: N
authors: Yamaguchi
authors: Masami
authors: M
authors: Ishibashi
mesh_terms: D002453:Cell Cycle / Q000187:drug effects*; D004247:DNA / Q000032:analysis; D016193:G1 Phase / Q000187:drug effects; D016195:G2 Phase / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D009235:Myxomycetes / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D026121:Indole Alkaloids; C480778:arcyriaflavin C; D004247:DNA