Bowen disease of the nail bed presenting as longitudinal melanonychia: detection of human papillomavirus type 56 DNA.
A case of Bowen disease (BD) presenting as longitudinal melanonychia (LM) on the right third fingernail of a 25-year-old African American man is described. Findings from the histopathologic examination revealed full-thickness epidermal atypia, hypergranulosis, and koilocytic changes. Human papillomavirus (HPV) type 56 was identified by polymerase chain reaction. To the best of our knowledge, we describe the first case of BD of the nail unit in which HPV-56 DNA has been identified.
Lambiase
Matthew C
MC
Department of Dermatology, San Antonio Uniformed Services Health Education Consortium, Fort Sam Houston, Texas, USA.
Gardner
Timothy L
TL
Altman
Coleman E
CE
Albertini
John G
JG
D000328:Adult; D001913:Bowen's Disease / Q000175:diagnosis* / Q000821:virology; D015344:DNA Probes, HPV; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000821:virology; D010304:Paronychia / Q000175:diagnosis* / Q000821:virology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000821:virology
D015344:DNA Probes, HPV