title: Treatment of osteoarthritic cartilage lesions with osteochondral autograft transplantation.
abstract: Twenty-two osteochondral autograft transplantations were performed on two types of knees: those with isolated (group 1) and multiple (group 2) degenerative cartilage lesions. At minimum 24-month follow-up, group 1 had significantly better pain relief and function than group 2 based on the Western Ontario and McMaster Universities Osteoarthritis Index and pain scores (10-point visual analog scale). Osteochondral autograft transplantation may be effective in treating knees with isolated degenerative cartilage lesions but appears contraindicated in those with multiple lesions.
authors: Johns Hopkins Bayview Medical Center, Baltimore, MD 21224-2780, USA.
authors: Brett M
authors: BM
authors: Andres
authors: Simon C
authors: SC
authors: Mears
authors: Deniz S
authors: DS
authors: Somel
authors: Ray
authors: R
authors: Klug
authors: James F
authors: JF
authors: Wenz
mesh_terms: D000368:Aged; D016025:Bone Transplantation / Q000379:methods*; D002358:Cartilage, Articular / Q000473:pathology / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy; D014182:Transplantation, Autologous; D016896:Treatment Outcome