Benzoxazinoids and iridoid glucosides from four Lamium species.
A new class of compounds for the plant family Lamiaceae, benzoxazinoids, was found in Lamium galeobdolon. From the aerial parts of the species were isolated the new 2-O-beta-D-glucopyranosyl-6-hydroxy-2H-1,4-benzoxazin-3(4H)-one (6-hydroxy blepharin) together with four known benzoxazinoids, DHBOA-Glc, blepharin, DIBOA, DIBOA-Glc, as well as harpagide, 8-O-acetyl-harpagide and salidroside. Eight known iridoid glucosides, 24-epi-pterosterone and verbascoside were isolated from Lamium amplexicaule, L. purpureum and L. garganicum. The iridoids, 5-deoxylamiol and sesamoside, as well as the phytoecdysone, 24-epi-pterosterone, were found for the first time for the genus Lamium. The phytochemical data are discussed from a systematic and evolutionary point of view.
Alipieva
Kalina I
KI
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria.
Taskova
Rilka M
RM
Evstatieva
Ljubka N
LN
Handjieva
Nedjalka V
NV
Popov
Simeon S
SS
D004440:Ecdysone / Q000737:chemistry / Q000302:isolation & purification; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D019686:Lamiaceae / Q000737:chemistry* / Q000235:genetics; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010078:Oxazines / Q000737:chemistry* / Q000302:isolation & purification*; D010802:Phylogeny; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification
D039823:Iridoids; D010078:Oxazines; D010840:Phytosterols; C021238:phytoecdysones; D004440:Ecdysone