title: A new algorithm for metal artifact reduction in computed tomography: in vitro and in vivo evaluation after total hip replacement.
abstract: OBJECTIVE
  To evaluate a newly developed algorithm for metal artifact reduction (MAR) in Computed Tomography (CT).
  
  
  METHODS
  A projection interpolation algorithm for MAR with threshold-based metal segmentation was developed. First, the algorithm was tested with a simulated hip phantom. On demand, the presence of metallic inserts was simulated, representing total hip endoprostheses. Second, CT data of 20 patient with total hip endoprosthesis were reconstructed with and without application of the MAR algorithm. Image quality was independently assessed by 2 experienced radiologists using a qualitative score. The results of the in vitro study were evaluated with the Student's t test. Results of the in vivo study were analyzed using a repeated-measure analysis of variance.
  
  
  RESULTS
  Applying the MAR algorithm the phantom study showed no significant difference between images with and without simulated metal contributions. The patient study revealed improved image quality using the MAR algorithm. Results were statistically significant for fat (P=0.0097), vessels (P=0.0091), and bone (P=0.0005). Improvement of the image quality for muscle was not statistically significant (P=0.0287).
  
  
  CONCLUSIONS
  A new algorithm for metal artifact reduction was successfully introduced into clinical routine. The algorithm led to a robust reduction of metal artifacts. The MAR algorithm may serve for an improvement in image quality in patients with metallic implants.
authors: Department of Diagnostic Radiology, Aachen University of Technology, Germany. mahnken@rad.rwth-aachen.de
authors: Andreas H
authors: AH
authors: Mahnken
authors: Rainer
authors: R
authors: Raupach
authors: Joachim E
authors: JE
authors: Wildberger
authors: Bettina
authors: B
authors: Jung
authors: Nicole
authors: N
authors: Heussen
authors: Thomas G
authors: TG
authors: Flohr
authors: Rolf W
authors: RW
authors: Günther
authors: Stefan
authors: S
authors: Schaller
mesh_terms: D000368:Aged; D000465:Algorithms; D000704:Analysis of Variance; D019644:Arthroplasty, Replacement, Hip; D016477:Artifacts; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008670:Metals; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed / Q000295:instrumentation
chemical_list: D008670:Metals