Transmission of Helicobacter pylori infection in families of preschool-aged children from Minas Gerais, Brazil.
We evaluated the role of the family in the transmission of Helicobacter pylori infection in preschool-aged children from a rural district in the State of Minas Gerais, Brazil. Sixty-six families (66 index children, 63 mothers, 60 fathers and 134 siblings), defined as at least one parent living in the same household with at least one offspring up to 8 years old, were studied. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression controlling for age, gender, number of children in household and H. pylori status of the father, mother and siblings. The prevalence of the infection was 69.7% (469 of 673) and it increased with age (P < 0.001). Positive mothers were a strong and independent risk factor for infection (OR 22.70; 95% CI 2.31-223.21). Positive siblings were also positively associated with infection (OR 1.81; 95% CI 1.01-3.30).
Rocha
Gifone Aguiar
GA
Laboratory of Research in Bacteriology, Faculdade de Medicina, UFMG, Belo Horizonte, Brazil. garocha@medicina.ufmg.br
Rocha
Andreia Maria Camargos
AM
Silva
Luciana Diniz
LD
Santos
Adriana
A
Bocewicz
Ana Carolina Dias
AC
Queiroz Rd
Renata de Magalhães
Rde M
Bethony
Jeffrey
J
Gazzinelli
Andréa
A
Corrêa-Oliveira
Rodrigo
R
Queiroz
Dulciene Maria Magalhães
DM
D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005190:Family; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology / Q000635:transmission*; D016480:Helicobacter pylori; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012423:Rural Health; D016036:Seroepidemiologic Studies