title: Long-term outcome in intensive care unit survivors after mechanical ventilation for intracerebral hemorrhage.
abstract: OBJECTIVE
  To evaluate long-term survival and functional outcome in intensive care unit survivors after mechanical ventilation for intracerebral hemorrhage.
  
  
  METHODS
  Retrospective chart review and prospective follow-up study.
  
  
  METHODS
  Outpatient follow-up.
  
  
  METHODS
  Between 1997 and 2000, 120 patients were mechanically ventilated for an intracerebral hemorrhage at our intensive care unit. Sixty-two patients were discharged from hospital (in-hospital mortality = 48%). Sixty patients were evaluated for survival and functional outcome (two were lost to follow-up). Time between discharge and follow-up was > or =1 yr and was a mean of 27 +/- 14 months (range, 12-56).
  
  
  METHODS
  None.
  
  
  RESULTS
  Patients' physicians were first asked about survival, and patients or proxies were interviewed by phone. Barthel Index and modified Rankin Scale scores were collected, and demographic information and general data were reviewed. The estimated life-table survival curve after discharge was 64.6% at 1 yr and 57% at 3 yrs. In the 24 patients who died, the mean time between discharge and death was 5 +/- 6 months. Probability of death after discharge significantly increased if age at admission was >65 yrs (p <.01; odds ratio, 3.5; 95% confidence interval, 1.4-9.1) and if Glasgow Coma Scale score at discharge was <15 (p <.01; odds ratio, 3.9; 95% confidence interval, 1.6-9.5). In the 36 long-term survivors, Barthel Index was 67.5 +/- 15 (median +/- median absolute dispersion) and modified Rankin Scale score was 2.6 +/- 0.5. Fifteen patients (42%) had a slight or no disability (Barthel Index > or =90 and modified Rankin Scale score < or =2), whereas 21 patients (58%) had moderate or severe disability (Barthel Index < or =85 and modified Rankin Scale score >2).
  
  
  CONCLUSIONS
  Probability of survival at 3 yrs after mechanical ventilation for an intracerebral hemorrhage was >50%. Age was an important determinant of long-term survival. Forty-two percent of long-term survivors were independent for activities of daily living. Only a few long-term survivors had a very high degree of disability.
authors: Service de Réanimation Polyvalente, Hôpitaux Sud, Marseilles, France.
authors: Antoine
authors: A
authors: Roch
authors: Pierre
authors: P
authors: Michelet
authors: Anne Céline
authors: AC
authors: Jullien
authors: Xavier
authors: X
authors: Thirion
authors: Fabienne
authors: F
authors: Bregeon
authors: Laurent
authors: L
authors: Papazian
authors: Pierre
authors: P
authors: Roche
authors: William
authors: W
authors: Pellet
authors: Jean-Pierre
authors: JP
authors: Auffray
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000401:mortality / Q000628:therapy*; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011336:Probability; D012121:Respiration, Artificial; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors