Interstitial photon radiation.
Most minimally invasive ablative techniques utilize thermal energies for tissue destruction. However, the heat-sink phenomenon may limit the efficacy of radiofrequency ablation and cryotherapy of tissue near blood vessels. One alternative non-temperature-dependent ablative technique is photon radiation. This radiation is dependent on energy and intensity, and its effects are influenced only by the density of the surrounding tissue. Photon radiation therapy may offer a unique alternative for ablating tissue surrounding vascular structures.
Chan
David Y
DY
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA. dchan@welchlink.welch.jhu.edu
Solomon
Stephen B
SB
Kavoussi
Louis R
LR
D000818:Animals; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D023421:Models, Animal; D009369:Neoplasms / Q000532:radiotherapy*; D017785:Photons / Q000627:therapeutic use*