Gut in diseases: physiological elements and their clinical significance.
The intestinal barrier function of GI tract is very important in the body except for the function of digestion and absorption. The functional status of gut barrier basically reflects the stress severity when body suffers from trauma and various stimulations. Many harmful factors such as drugs, illnesses, trauma and burns can damage the gut barrier, which can lead to the barrier dysfunction and bacterial/endotoxin translocation. The paper discusses and reviews the concepts, anatomy, pathophysiology of gut barrier and its clinical relations.
Ding
Lian-An
LA
Department of General Surgery, Affilitated Hospital of Medical School, Qingdao University, Qingdao 266003, Shandong Province, China. dlahaolq@hotmail.com
Li
Jie-Shou
JS
D000818:Animals; D018988:Bacterial Translocation; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology*; D007410:Intestinal Diseases / Q000378:metabolism* / Q000382:microbiology / Q000503:physiopathology*