title: Multiple brain abscesses in a patient with bilateral pulmonary arteriovenous malformations and immunoglobulin deficiency.
abstract: A 34 year old Chinese man presented with grand mal seizures complicating multiple brain abscesses caused by mixed oral flora. Because of persistent hypoxaemia contrast spiral thoracic computed tomography was done, which revealed bilateral pulmonary arteriovenous malformations (PAVMs). Concomitant IgA and IgG subclass deficiency was also found. The combination of these two conditions appears to have predisposed this patient to presumably paradoxical septic embolism. The patient's cerebral condition responded to postoperative antibiotic treatment and he eventually received selective coil embolisation of right lower lobe PAVMs, which relieved his hypoxaemia and dyspnoea.
authors: Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
authors: K-C
authors: KC
authors: Tse
authors: G C
authors: GC
authors: Ooi
authors: A
authors: A
authors: Wu
authors: P L
authors: PL
authors: Ho
authors: S K
authors: SK
authors: Ip
authors: M H
authors: MH
authors: Jim
authors: Y M
authors: YM
authors: Lam
authors: Y W
authors: YW
authors: Fan
authors: W K
authors: WK
authors: Tso
authors: K W
authors: KW
authors: Tsang
mesh_terms: D000328:Adult; D001165:Arteriovenous Malformations / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001922:Brain Abscess / Q000150:complications* / Q000175:diagnosis; D004417:Dyspnea / Q000209:etiology / Q000628:therapy; D004621:Embolization, Therapeutic / Q000379:methods; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy; D017098:IgA Deficiency / Q000150:complications*; D017099:IgG Deficiency / Q000150:complications*; D018810:Magnetic Resonance Angiography / Q000379:methods; D008297:Male; D011651:Pulmonary Artery / Q000002:abnormalities*; D014057:Tomography, X-Ray Computed / Q000379:methods