[Candida parapsilosis endocarditis after prolonged antibiotic therapy].
Infective endocarditis is still a very serious disease whose prognosis has improved in recent years, even though advanced technologies have brought a greater number of cases attributable to increased growth of fungi in more virulent forms. We describe a case of endocarditis caused by Candida parapsilosis on a previously healthy aortic valve in a man who had received prolonged intravenous antibiotic treatment a few months earlier. The initial presentation included acute arterial ischaemia of the lower limbs. The diagnosis of endocarditis was then confirmed by echocardiography and microbiology. Specific antifungal therapy was started, and embolectomy and valve replacement were performed; however, the infection could not be controlled and the patient died a few days later.
Castillo Caparrós
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Servicio de Anestesiología y Reanimación, Hospital Clínico-Universitario Virgen de la Victoria de Málaga. acastilloc@medynet.com
Montijano Cabrera
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AM
D002175:Candida / Q000145:classification / Q000302:isolation & purification*; D002177:Candidiasis / Q000209:etiology / Q000382:microbiology*; D002305:Cardiac Tamponade / Q000209:etiology; D002437:Cefazolin / Q000008:administration & dosage / Q000009:adverse effects*; D004198:Disease Susceptibility; D004359:Drug Therapy, Combination / Q000009:adverse effects*; D004696:Endocarditis / Q000209:etiology / Q000382:microbiology*; D017809:Fatal Outcome; D006801:Humans; D007511:Ischemia / Q000209:etiology; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology / Q000382:microbiology*; D010397:Penicillanic Acid / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D010878:Piperacillin / Q000008:administration & dosage / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology / Q000382:microbiology*; D015163:Superinfection; D000078142:Tazobactam
D010397:Penicillanic Acid; D002437:Cefazolin; D000078142:Tazobactam; D010878:Piperacillin