[Pemphigoid gestationis and vasculorenal syndrome: a fortuitous association?].
Pemphigoid gestationis is a gestational skin disease usually appearing between the 28th and the 32nd week of amenorrhea. It is a rare vesiculobullous skin disease and the eruption is located around the umbilicus. The diagnosis is made with clinical symptoms but mainly on histologic examination (after skin biopsy) and direct immunofluorescence. One of the main complications is the rate of recurrence. The main treatment is based on topical corticosteroids. The effects of the pemphigoid gestationis are maternal (preterm labor), fetal (intrauterine growth retardation) and neonatal (bullous disease). We report a case of pemphigoid gestationis associated to a gestational hypertensive disorder and we try to rely on both entities.
Aicardi
S
S
Clinique de gynécologie-obstétrique, CHU de Caen, avenue Georges-Clemenceau, 14033 Caen, France.
Durin
L
L
Dompmartin
A
A
Dreyfus
M
M
D000279:Administration, Cutaneous; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D006978:Hypertension, Renovascular / Q000150:complications* / Q000188:drug therapy; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000473:pathology; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy; D011256:Pregnancy Outcome; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents