title: Cynthichlorine: a bioactive alkaloid from the tunicate Cynthia savignyi.
abstract: From ether extracts of the tunicate Cynthia savignyi, collected in Morocco, a new alkaloid-cynthichlorine-has been isolated. The structure of cynthichlorine has been characterized by extensive 2D-NMR data. Cynthichlorine possesses antifungal activity against two tomato pathogenic fungi: Botrytis cinerea and Verticillium albo atrum and antibacterial activity against Agrobacterium radiobacter, Escherichia coli and Pseudomonas aeruginosa and cytotoxicity against Artemia salina larvae.
authors: Laboratoire de Chimie Organique Biomoléculaire Associé au C.N.R, Faculté des Sciences Ben M'Sik, BP 7955 Casablanca, Maroc. a.abourriche@univh2m.ac.ma
authors: A
authors: A
authors: Abourriche
authors: Y
authors: Y
authors: Abboud
authors: S
authors: S
authors: Maoufoud
authors: H
authors: H
authors: Mohou
authors: T
authors: T
authors: Seffaj
authors: M
authors: M
authors: Charrouf
authors: N
authors: N
authors: Chaib
authors: A
authors: A
authors: Bennamara
authors: N
authors: N
authors: Bontemps
authors: C
authors: C
authors: Francisco
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects; D017606:Chlorine Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D014561:Urochordata
chemical_list: D000470:Alkaloids; D000890:Anti-Infective Agents; D017606:Chlorine Compounds