Fetal neurologic consultations.
The pediatric neurologist can fulfill a useful role as a subspecialty consultant concerning the fetus with a suspected brain disorder, given that neurologic disease may occur before the intrapartum period. Brain disorders detected in the neonatal period may also reflect fetal brain damage before dysfunction is first documented. Medical conditions during the antepartum or intrapartum periods can alternatively predispose the fetus or neonate to express brain dysfunction at a later period, with either de novo or compounded brain injury. The pediatric neurologist must, therefore, consider maternal, placental, and fetal diseases on which a neonatal encephalopathy may be superimposed. This review article provides the neurologist with an integrative approach to fetal neurology, emphasizing perspectives from other subspecialties concerning maternal-fetal medicine, pathology, and neonatology, as well as other pediatric subspecialties. Evaluation of future strategies for either fetal or neonatal brain resuscitation will need to consider the developmental context in which a suspected brain injury occurred during the antepartum, intrapartum, and neonatal periods.
Scher
Mark S
MS
Department of Pediatrics, Rainbow Babies and Children's Hospital, University Hospitals of Cleveland, Case-Western Reserve University School of Medicine, Cleveland, Ohio 44106-6090, USA.
D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011247:Pregnancy; D012017:Referral and Consultation; D016216:Ultrasonography, Prenatal / Q000379:methods