title: A case of renal cell carcinoma with bone and lymph node metastases.
abstract: We present a rare case of renal cell carcinoma (RCC) with a metastatic, mainly osteoblastic lesion of the skull and spread to the lymph nodes. Renal tumors are often associated with bone metastases; these are most often of the osteolytic type, while osteoblastic metastases are extremely rare. In the case presented here, the primary metastasis was a large osteoblastic lesion of the skull that spread to the lymph nodes. The patient has undergone treatment for 20 months with interleukin-2: 3 million IU/day (subcutaneous) for six consecutive days once every four weeks, ie a total weekly dose of 18 million IU.
authors: Department of Experimental Medicine and Pathology, Special Oncology Service, Policlinico Umberto I, University of Rome La Sapienza, Italy. marisadiseri@yahoo.com
authors: Marisa
authors: M
authors: Di Seri
authors: Attilio
authors: A
authors: Verì
authors: Marialuisa
authors: M
authors: Colloca
authors: Bruno
authors: B
authors: Spalletta
authors: Rosalinda
authors: R
authors: Rossi
authors: Pia Pierpaola
authors: PP
authors: Petrella
authors: Deborah
authors: D
authors: Coletta
authors: Fausto
authors: F
authors: Petricola
authors: Serena
authors: S
authors: Ricciardi
authors: Luigi
authors: L
authors: Frati
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000008:administration & dosage; D007680:Kidney Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D007376:Interleukin-2