title: Littoral cell angioma of the spleen in a patient with severe aplastic anaemia.
abstract: Littoral cell angioma (LCA) is a rare benign tumour of the spleen. We describe a patient with aplastic anaemia who, following multiple treatments with rabbit and horse Anti-Thymocyte Globulin and anabolic steroids developed marked splenomegaly and hypersplenism. LCA was diagnosed post splenectomy. This is the first case of LCA associated with aplastic anaemia and its treatment.
authors: Department of Haematology and Histopathology, Manchester Royal Infirmary, Manchester, UK.
authors: Eleni
authors: E
authors: Tholouli
authors: Jo-An
authors: JA
authors: Roulson
authors: Richard
authors: R
authors: Byers
authors: Ian
authors: I
authors: Burton
authors: John A
authors: JA
authors: Liu Yin
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy; D000818:Animals; D000961:Antilymphocyte Serum / Q000009:adverse effects; D001803:Blood Transfusion; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006391:Hemangioma / Q000139:chemically induced / Q000150:complications*; D006736:Horses; D006801:Humans; D006971:Hypersplenism / Q000209:etiology; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D010110:Oxymetholone / Q000009:adverse effects / Q000627:therapeutic use; D011817:Rabbits; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000139:chemically induced / Q000150:complications*; D013601:T-Lymphocytes
chemical_list: D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D010110:Oxymetholone