Temporomandibular response to early and late removal of bite-jumping devices.
This study was designed to monitor the amount of bone formed after 'early' and 'late' removal of bite-jumping devices and to compare it with that of normal growth. One hundred and thirty-five 35-day-old female Sprague-Dawley rats were randomly divided into seven control (n = 5) and 10 experimental (n = 10) groups. Appliances were fitted to position the mandible forward in the experimental groups. On day 30, the bite-jumping device was removed in two groups ('early' removal) and the rats were sacrificed on days 44 and 60. On day 44 the device was removed in one group ('late' removal) and the rats were sacrificed on day 60. The full-time wear and matched control animals were then sacrificed at different time points. Tissue sections (7 microm) were cut through the temporomandibular joint (TMJ) in the sagittal plane and stained with periodic acid and Schiff's reagent for the evaluation of new bone formation. Newly formed bone was measured using a computer-assisted image analysing system. The results showed that, in the condyle, early removal of the appliance resulted in less bone formation when compared with that of natural growth. Late removal of the appliance resulted in bone formation similar to that of natural growth. In the glenoid fossa, the level of bone formation was similar to that of the control at early and late removal of the appliance. In conclusion, early appliance removal results in subnormal growth of the posterior condyle but not of the glenoid fossa. Increasing the length of mandibular advancement secures normal levels of mandibular growth in the post-treatment period.
Chayanupatkul
Atinooch
A
Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Rabie
A B M
AB
Hägg
Urban
U
D000202:Activator Appliances; D000818:Animals; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D019186:Mandibular Advancement / Q000295:instrumentation*; D008335:Mandibular Condyle / Q000254:growth & development*; D008445:Maxillofacial Development; D010012:Osteogenesis; D051381:Rats; D017207:Rats, Sprague-Dawley; D013704:Temporomandibular Joint / Q000254:growth & development*; D013997:Time Factors