title: Online tool for the discrimination of equi-distributions.
abstract: BACKGROUND
  For many applications one wishes to decide whether a certain set of numbers originates from an equiprobability distribution or whether they are unequally distributed. Distributions of relative frequencies may deviate significantly from the corresponding probability distributions due to finite sample effects. Hence, it is not trivial to discriminate between an equiprobability distribution and non-equally distributed probabilities when knowing only frequencies.
  
  
  RESULTS
  Based on analytical results we provide a software tool which allows to decide whether data correspond to an equiprobability distribution. The tool is available at http://bioinf.charite.de/equifreq/.
  
  
  CONCLUSIONS
  Its application is demonstrated for the distribution of point mutations in coding genes.
authors: Charité, Institut für Biochemie, Monbijoustrasse 2, D-10117, Berlin, Germany. thorsten.poeschel@charite.de
authors: Thorsten
authors: T
authors: Pöschel
authors: Cornelius
authors: C
authors: Frömmel
authors: Christoph
authors: C
authors: Gille
mesh_terms: D000595:Amino Acid Sequence / Q000235:genetics; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D005796:Genes / Q000235:genetics; D020407:Internet / Q000706:statistics & numerical data; D015233:Models, Statistical; D008969:Molecular Sequence Data; D009862:Online Systems / Q000706:statistics & numerical data*; D017354:Point Mutation / Q000235:genetics; D011110:Polymorphism, Genetic / Q000235:genetics; D012984:Software / Q000706:statistics & numerical data; D016008:Statistical Distributions
chemical_list: D019005:Cystic Fibrosis Transmembrane Conductance Regulator