title: A new synthetic approach to the C ring of known as well as novel bryostatin analogues.
abstract: [reaction: see text] A new approach to the synthesis of the C ring subunit of known and potential bryostatin analogues is described. The convergent approach, illustrated above, requires fewer steps and offers greater flexibility in rapidly accessing diverse C ring analogues.
authors: Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. wenderp@stanford.edu
authors: Paul A
authors: PA
authors: Wender
authors: Michael F T
authors: MF
authors: Koehler
authors: Martin
authors: M
authors: Sendzik
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D054713:Bryostatins; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D018942:Macrolides; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D054713:Bryostatins; D007783:Lactones; D018942:Macrolides; C046785:bryostatin 1