title: Allergic granulomatosis and angiitis in the absence of asthma and blood eosinophilia: a rare presentation of limited Churg-Strauss syndrome.
abstract: Allergic granulomatosis and angiitis, also known as Churg-Strauss syndrome (CSS), is an uncommon vasculitis of unknown etiology. We report a 21-year-old male patient with fatigue, dry cough, and progressive dyspnea. He had no history of asthma or eosinophilia. Thorax computed tomography showed bullous/cystic areas with thin walls in varying sizes (5-15 mm). Histopathological examination of the open lung biopsy revealed granulomatous infiltration with histiocytes and eosinophilic leukocytes. This extremely rare variant of CSS is discussed.
authors: Department of Internal Medicine, Gaziantep University School of Medicine, Sahinbey Medical Center, Gaziantep 27310, Turkey. sevinc@gantep.edu.tr
authors: Alper
authors: A
authors: Sevinc
authors: H Canan
authors: HC
authors: Hasanoglu
authors: Munire
authors: M
authors: Gokirmak
authors: Zeki
authors: Z
authors: Yildirim
authors: Tamer
authors: T
authors: Baysal
authors: Bulent
authors: B
authors: Mizrak
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis; D001980:Bronchi / Q000473:pathology; D002634:Chemotaxis, Leukocyte / Q000502:physiology; D015267:Churg-Strauss Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis; D004804:Eosinophils / Q000166:cytology; D006644:Histiocytes / Q000166:cytology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D008775:Methylprednisolone