Hidradenitis suppurativa associated with Crohn's disease and spondyloarthropathy: response to anti-TNF therapy.
An association of hidradenitis suppurativa with Crohn's disease is supported by previous repent. We here report a patient with hidradenitis suppurativa who subsequently developed peripheral arthritis, sacroiliitis, and Crohn's disease. A significant attenuation of bowel, cutaneous, and joint symptoms was achieved after treatment with monoclonal antibody against tumor necrosis factor (TNF). The pathogenetic aspects according to the literature and response to the various therapeutic measures applied are also presented.
Roussomoustakaki
Maria
M
Department of Gastroenterology, University Hospital of Heraklion, University General Hospital, PO Box 1352, 71110, Crete, Heraklion, Greece.
Dimoulios
Philippos
P
Chatzicostas
Constantinos
C
Kritikos
Heraklis D
HD
Romanos
John
J
Panayiotides
John G
JG
Kouroumalis
Elias A
EA
D000328:Adult; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001365:Axilla / Q000473:pathology; D001379:Azathioprine / Q000627:therapeutic use; D003424:Crohn Disease / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D017497:Hidradenitis Suppurativa / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D012446:Sacroiliac Joint / Q000473:pathology*; D025242:Spondylarthropathies / Q000188:drug therapy / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha; D001379:Azathioprine