title: Cortical field potentials preceding self-paced forelimb movements and influences of cerebellectomy upon them in rats.
abstract: Seven rats were well trained to move lever to the left by right forelimb at self-pace (self-paced forelimb movements). Cortical field potentials associated with self-paced forelimb movements were recorded by electrodes implanted chronically on the surface and at a 2.0 mm depth in the forelimb motor cortex on the left side. A surface-negative, depth-positive potential starting about 1.0 s prior to the movement was recorded in the rostral part of the forelimb motor cortex. Further we found that the premovement potential was eliminated by the cerebellar hemispherectomy on the right side. This suggests the participation of the cerebellar hemisphere in preparing the activity of the motor cortex before self-paced forelimb movements in rats, by cerebello-thalamo-cortical projections.
authors: Department of Physiology, Kansai Medical University, Moriguchi 570-8506, Japan.
authors: Hiroko
authors: H
authors: Ohishi
authors: Jun
authors: J
authors: Ichikawa
authors: Ryuichi
authors: R
authors: Matsuzaki
authors: Shin ichi
authors: Si
authors: Kyuhou
authors: Kazuko
authors: K
authors: Matsuura-Nakao
authors: Tomomi
authors: T
authors: Seki
authors: Hisae
authors: H
authors: Gemba
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002531:Cerebellum / Q000502:physiology* / Q000601:surgery; D005260:Female; D005552:Forelimb / Q000502:physiology*; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar