Fast mapping of protein-protein interfaces by NMR spectroscopy.
Identifying the interface of protein complexes can represent a difficult task in structural biology. Here, we report a method for the fast mapping of interfaces of protein complexes by NMR without the need for the assignments of the proteins involved.
Reese
Michael L
ML
Graduate Group in Biophysics, University of California-San Francisco, San Francisco, CA 94143, USA.
Dötsch
Volker
V
D001665:Binding Sites; D009419:Nerve Tissue Proteins / Q000737:chemistry* / Q000378:metabolism; D019001:Nitric Oxide Synthase / Q000737:chemistry* / Q000378:metabolism; D052248:Nitric Oxide Synthase Type I; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D010449:Peptide Mapping / Q000379:methods; D011487:Protein Conformation; D017434:Protein Structure, Tertiary
D009419:Nerve Tissue Proteins; C033652:postsynaptic density proteins; D019001:Nitric Oxide Synthase; D052248:Nitric Oxide Synthase Type I