Acute appendicitis with fulminant necrotizing fasciitis in a neonate.
The authors report on a neonate who presented with acute appendicitis and who went on to have fatal necrotizing fasciitis. Although recognized in adults, this rare combination of conditions has not been reported previously in the neonate and requires rapid recognition with aggressive medical and surgical intervention.
Lodha
Abhay
A
Division of Neonatology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
Wales
Paul W
PW
James
Andrew
A
Smith
Charles R
CR
Langer
Jacob C
JC
D000208:Acute Disease; D001062:Appendectomy; D001064:Appendicitis / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D002981:Clindamycin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000302:isolation & purification; D019115:Fasciitis, Necrotizing / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D017809:Fatal Outcome; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy; D041121:Klebsiella oxytoca / Q000302:isolation & purification; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D011183:Postoperative Complications; D012772:Shock, Septic / Q000188:drug therapy / Q000209:etiology; D013203:Staphylococcal Infections / Q000150:complications / Q000188:drug therapy
D010406:Penicillins; D008795:Metronidazole; D002981:Clindamycin