Allergic fungal sinusitis associated with Trichoderma longibrachiatum.
We describe allergic fungal sinusitis caused by Trichoderma longibrachiatum in a patient with a history of atopy and asthma. A Gram stain of a sinus biopsy specimen was initially thought to contain yeast cells, but when Trichoderma was recovered in culture, these cells were subsequently recognized as chlamydospores. The patient was successfully managed with a combination of sinus lavage, oral corticosteroids, itraconazole, and allergen immunotherapy. This case also points out that careful scrutiny of direct smears is required to ensure that fungal structures are not misinterpreted.
Tang
Patrick
P
Department of Microbiology, Toronto Medical Laboratories and Mount Sinai Hospital, Toronto, Ontario, Canada.
Mohan
Subhash
S
Sigler
Lynne
L
Witterick
Ian
I
Summerbell
Richard
R
Campbell
Iivi
I
Mazzulli
Tony
T
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000485:Allergens / Q000276:immunology; D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology / Q000382:microbiology; D017964:Itraconazole / Q000627:therapeutic use; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000175:diagnosis*; D012852:Sinusitis / Q000382:microbiology* / Q000473:pathology; D016896:Treatment Outcome; D014242:Trichoderma / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification
D000305:Adrenal Cortex Hormones; D000485:Allergens; D000935:Antifungal Agents; D017964:Itraconazole