title: A general strategy for the diastereoselective synthesis of 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane lignans.
abstract: A strategy for the stereoselective synthesis of all the possible diastereoisomers of the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane (furofuran) lignans from a single dihydrofuran precursor is described. The key steps involve a diastereocontrolled templated cationic cyclization followed by stereoselective reduction of the resulting methyl glycoside.
authors: Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK.
authors: David J
authors: DJ
authors: Aldous
authors: Anne J
authors: AJ
authors: Dalençon
authors: Patrick G
authors: PG
authors: Steel