title: Synthesis of poly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamic acid) block copolymer using amino organic calcium catalyst.
abstract: A biodegradable two block copolymer, poly(epsilon-caprolactone)-b- poly(gamma-benzyl-L-glutamic acid) (PCL-PBLG) was synthesized successfully by ring-opening polymerization of N-carboxyanhydride of gamma-benzyl-L-glutamate (BLG-NCA) with aminophenyl-terminated PCL as a macroinitiator. The aminophenethoxyl-terminated PCL was prepared via hydrogenation of a 4-nitrophenethoxyl-terminated PCL, which was novelly obtained from the polymerization of epsilon-caprolactone (CL) initiated by amino calcium 4-nitrobenzoxide. The structures of the block copolymer and its precursors from the initial step of PCL were confirmed and investigated by 1H NMR, FT-IR, GPC, and FT-ICRMS analyses and DSC measurements.
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors: Guangzhuo
authors: G
authors: Rong
authors: Mingxiao
authors: M
authors: Deng
authors: Chao
authors: C
authors: Deng
authors: Zhaohui
authors: Z
authors: Tang
authors: Longhai
authors: L
authors: Piao
authors: Xuesi
authors: X
authors: Chen
authors: Xiabin
authors: X
authors: Jing
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis; D001673:Biodegradation, Environmental; D002118:Calcium; D002384:Catalysis; D015394:Molecular Structure; D011091:Polyesters / Q000138:chemical synthesis*; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013057:Spectrum Analysis
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters; C016240:polycaprolactone; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; D002118:Calcium