title: [A case of gastric cancer with peritoneal dissemination which showed the intraperitoneal CR by administrating TS-1 orally and paclitaxel intraperitoneally].
abstract: A 66-year-old male was diagnosed with advanced gastric cancer with pylorus stenosis, and the first abdominal computed tomography (CT) revealed a large amount of ascites. A staging laparoscopy revealed peritoneal dissemination and positive cytology for numerous amounts of ascites (s-T3(SE), N0, M0, p(+), cy(+), H0, s-Stage IV). The patient received TS-1 orally and paclitaxel administered to the peritoneal cavity. After finishing the second course of the combined chemotherapy, second-look staging laparoscopy was performed, which showed the disappearance of peritoneal dissemination and negative cytology. Chemotherapy combined with oral TS-1 and paclitaxel administered to the peritoneal cavity might be an effective strategy against advanced gastric cancer with peritoneal dissemination.
authors: Dept. of Surgery, Kansai Rosai Hospital.
authors: Hirofumi
authors: H
authors: Miki
authors: Shigeyuki
authors: S
authors: Tamura
authors: Hiroshi
authors: H
authors: Wada
authors: Yasuyuki
authors: Y
authors: Kozuma
authors: Nobuyoshi
authors: N
authors: Kittaka
authors: Tyuwan
authors: T
authors: Kim
authors: Daisuke
authors: D
authors: Takiuchi
authors: Tomohiko
authors: T
authors: Aihara
authors: Keiji
authors: K
authors: Sugimoto
authors: Mutsumi
authors: M
authors: Fukunaga
authors: Hiroki
authors: H
authors: Ozato
authors: Naohiro
authors: N
authors: Tomita
authors: Yuichi
authors: Y
authors: Takatsuka
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D010529:Peritoneal Cavity; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D011725:Pyridines / Q000008:administration & dosage; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000473:pathology*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel