DTPA renal scan assessment of renal allograft dysfunction in rats.
The precise cause of allograft dysfunction after renal transplantation often cannot be established by non-invasive means. In clinical practice, radionuclide scans form an integral part of the clinician's armamentarium in the assessment of these patients. Unfortunately, in the clinical setting more than one pathological process may be responsible for the impaired function, making it difficult to correlate the scan appearances with the pathology. In this study in rats we compared the renal DTPA scan appearances of the various pathological processes which may cause renal allograft dysfunction in the immediate post-transplant period.
Dickerson
D
D
Department of Surgery, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Adams
B
B
Engelbrecht
G
G
Boltman
G
G
Hickman
R
R
Kahn
D
D
D000818:Animals; D016572:Cyclosporine / Q000633:toxicity; D006084:Graft Rejection / Q000000981:diagnostic imaging; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology*; D016030:Kidney Transplantation / Q000009:adverse effects / Q000473:pathology / Q000502:physiology*; D008297:Male; D004369:Pentetic Acid; D011859:Radiography; D011866:Radioisotope Renography / Q000379:methods; D051381:Rats; D020318:Rats, Long-Evans; D012079:Renal Circulation; D014184:Transplantation, Homologous; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000209:etiology
D004369:Pentetic Acid; D016572:Cyclosporine