Randomized controlled trial of a new dietary education program to prevent type 2 diabetes in a high-risk group of Japanese male workers.
OBJECTIVE
The aim of this study was to assess the effectiveness of a new dietary education (NDE) program in reducing plasma glucose (PG) levels in Japanese male workers at high risk for type 2 diabetes through a randomized controlled trial.


METHODS
We randomly assigned 173 high-risk men (mean age, 55 years) to either the NDE or the control (conventional dietary education) group. Each subject in the NDE group received two individualized interventions especially aimed at reducing total energy intake at dinner by modifying dietary intake. The control group received conventional group counseling. An "overintake/underintake fraction" for total energy intake was used to measure the status of dietary intake. Our hypothesis was that the NDE group would have a 10% decrease in 2-h PG 1 year after the start of the education. Outcome measures were compared with ANCOVA by adjusting for baseline values.


RESULTS
The NDE group had a significantly lower total energy intake at dinner and daily than the control group. The adjusted differences in changes from baseline in the absolute value of the 'overintake/underintake fraction' were -15.3% (95% CI -24.6 to -6.0%, P = 0.002) for dinner and -6.0% (-9.8 to -2.2%, P = 0.002) for daily [corrected]. The NDE group had a decreased 2-h PG after 1 year, whereas that value was increased in the control group. The adjusted difference in the percent change of 2-h PG was significant (-15.2%, -22.0 to -8.4%, P < 0.001).


CONCLUSIONS
The NDE was shown to reduce glucose levels in high-risk subjects for type 2 diabetes.
Watanabe
Mariko
M
Department of Human Nutrition, Graduate School of Human Ecology, Showa Women's University, Shibuya-ku, Tokyo, Japan.
Yamaoka
Kazue
K
Yokotsuka
Masako
M
Tango
Toshiro
T
D001794:Blood Pressure; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D002149:Energy Intake; D005951:Glucose Tolerance Test; D006801:Humans; D007564:Japan; D008055:Lipids / Q000097:blood; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic / Q000379:methods* / Q000592:standards*; D012307:Risk Factors; D012907:Smoking
D008055:Lipids