Order, disorder, and flexibility: prediction from protein sequence.
The new predictor of disordered protein regions (disEMBL) introduced in this issue of Structure represents a computational tool developed to aid structural biologists in the design of protein constructs that avoid disordered protein regions in order to increase the success rate of structure determination.
Iakoucheva
Lilia M
LM
The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
Dunker
A Keith
AK
D000465:Algorithms; D019295:Computational Biology; D018360:Crystallography, X-Ray; D030562:Databases, Protein; D011487:Protein Conformation; D011489:Protein Denaturation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
D011506:Proteins