title: A novel approach to substituted 2H-azirines.
abstract: 2-(Benzotriazol-1-yl)-2H-azirines 4a-c, obtained by treatment of oximes 2a-c with tosyl chloride and aqueous KOH, were reacted with benzylmagnesium bromide or 4-methylbenzylmagnesium bromide in the presence of zinc chloride to give 2-benzyl-2H-azirines 5a-f. Potassium phthalimide and sodium salt of benzenethiol converted 2-(benzotriazol-1-yl)-2H-azirines 4a-c into novel 2H-azirines 6a-c and 7 in good yields.
authors: Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
authors: Alan R
authors: AR
authors: Katritzky
authors: Mingyi
authors: M
authors: Wang
authors: Chavon R
authors: CR
authors: Wilkerson
authors: Hongfang
authors: H
authors: Yang