title: Role of Chlamydia pneumoniae and Mycoplasma pneumoniae as causative agents of community-acquired pneumonia in hospitalised children and adolescents.
abstract: The aim of the study presented here was to determine the prevalence of Chlamydia pneumoniae versus Mycoplasma pneumoniae infections in paediatric patients with community-acquired pneumonia. A total of 50 patients (mean age, 5.5 years; median, 3.9 years) with community-acquired pneumonia were enrolled. Four patients were found to have Chlamydia pneumoniae infection (1 culture positive, 1 PCR positive and 2 serology positive) and 16 patients had Mycoplasma pneumoniae infection (2 PCR positive, 4 PCR and serology positive, 10 serology positive), including three patients with coinfection. The rates of Mycoplasma pneumoniae infection were 22%, 35% and 40% in children aged 1-3, >3-7 and >7 years, respectively. Acute Chlamydia pneumoniae infection was substantially less common than Mycoplasma pneumoniae infection in our study cohort.
authors: University Children's Hospital, P.O. Box, 4005 Basel, Switzerland.
authors: G
authors: G
authors: Baer
authors: G
authors: G
authors: Engelcke
authors: M
authors: M
authors: Abele-Horn
authors: U B
authors: UB
authors: Schaad
authors: U
authors: U
authors: Heininger
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D023521:Chlamydophila Infections / Q000175:diagnosis* / Q000453:epidemiology; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D015331:Cohort Studies; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000453:epidemiology; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis* / Q000453:epidemiology; D015995:Prevalence; D011336:Probability; D011379:Prognosis; D018570:Risk Assessment; D017678:Sex Distribution; D013557:Switzerland / Q000453:epidemiology