title: Brucella spondylitis and sacroiliitis in the general population in Mumbai.
abstract: OBJECTIVE
  1) To identify patients of brucella spondylitis and sacroiliitis amongst patients of 'infective spondylitis' and 'sacroiliitis', 2) To study clinical and radiographic features and outcome of brucella spondylitis.
  
  
  METHODS
  We reviewed 21 patients of infective spondylitis and 12 of sacroiliitis attending our hospital between March and September 2000 and followed them to identify patients of brucella spondylitis and brucella sacroiliitis, using serological tests.
  
  
  RESULTS
  1) Twenty six patients (17 spondylitis and nine sacroiliitis) were detected to have brucella infection to be the cause of their illness. 2) Brucella spondylitis is commonly mistaken for tuberculous spondylitis in our country. Thus leading to a delay in the diagnosis as well as occurrence of angular deformity and neurological deficit, which are reportedly uncommon in this condition. 3) Consumption (or handling) of unpasteurized milk (tabela milk) and occasional animal contact were found to be the source of infection in the general population. 4) Predominantly lumbar spine involvement, end-plate erosion of L4, L3, L5, decreased intervertebral disc space, repair with'formation of an osteophyte, simultaneous involvement of several sites and association of spondylitis with sacroiliitis were important radiographic features.
  
  
  CONCLUSIONS
  Brucellosis exists in the general population, high clinical suspicion especially when there is history of animal contact or consumption of unpasteurized milk, familiarity with clinical and radiological features of brucella spondylitis and detection of antibodies to brucella by ELISA will help us detect and treat these patients in time.
authors: Department of Medicine and Rheumatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, 400 022.
authors: Y A
authors: YA
authors: Gokhale
authors: A G
authors: AG
authors: Ambardekar
authors: A
authors: A
authors: Bhasin
authors: M
authors: M
authors: Patil
authors: A
authors: A
authors: Tillu
authors: Jyoti
authors: J
authors: Kamath
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood; D002003:Brucella abortus; D017347:Brucella melitensis; D002006:Brucellosis / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D004318:Doxycycline / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000627:therapeutic use; D012446:Sacroiliac Joint; D013166:Spondylitis / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000907:Antibodies, Bacterial; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D004318:Doxycycline; D012293:Rifampin