title: Evolution of penicillin and erythromycin co-resistance in Streptococcus pneumoniae in Spain.
abstract: The temporal dynamics of penicillin and erythromycin co-resistance in Streptococcus pneumoniae based on two extensive multicentre Spanish surveillance SAUCE studies (1996-1997 and 1998-1999) is presented. Erythromycin resistance among penicillin non-susceptible isolates seems to have reached a limit as evidenced by a null increase between the two surveys, whereas it is growing among penicillin-susceptible pneumococci.
authors: Medical Department, GlaxoSmithKline, Madrid, Spain.
authors: C
authors: C
authors: García-Rey
authors: E
authors: E
authors: Bouza
authors: L
authors: L
authors: Aguilar
authors: J
authors: J
authors: García-de-Lomas
authors: F
authors: F
authors: Baquero
mesh_terms: D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D004917:Erythromycin / Q000494:pharmacology*; D019143:Evolution, Molecular; D006801:Humans; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D011159:Population Surveillance; D013030:Spain; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D010406:Penicillins; D004917:Erythromycin