Iodine concentration in different human brain parts.
Iodine is one of the most important essential elements as demonstrated by the fact that its deficiency can cause goitre. Nevertheless, quantitative data on its concentration in biological materials, especially in the human brain, are scarce. There is therefore a demand for accurate and reliable information on iodine in these types of samples. The purpose of the present work was to determine the concentration of total iodine in some control human brain parts by rapid radiochemical neutron activation analysis. Our second goal was to determine I distribution between lipid fraction and in brain tissue without lipid by applying two types of solvent extraction methods. The results were checked by the analysis of biological standard reference materials with certified or literature values for iodine and good agreement was found.
Andrási
E
E
Institute of Inorganic and Analytical Chemistry, L. Eötvös University, Budapest, Hungary.
Bélavári
Cs
C
Stibilj
V
V
Dermelj
M
M
Gawlik
D
D
D000368:Aged; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism; D001923:Brain Chemistry; D005858:Germany; D006042:Goiter / Q000378:metabolism; D006801:Humans; D007455:Iodine / Q000032:analysis* / Q000737:chemistry; D007457:Iodine Radioisotopes; D008875:Middle Aged; D009501:Neutron Activation Analysis / Q000379:methods*; D012680:Sensitivity and Specificity
D007457:Iodine Radioisotopes; D007455:Iodine