DNA sequence design based on template strategy.
In DNA based computation and DNA nanotechnology, the design of proper DNA sequences has turned out to be an elementary problem. This paper takes a further look at the template strategy proposed in work by Frutos, A. G. et al. (Nucleic Acids Res. 1997, 25, 4748-4757). The H-measure proposed by Garzon et al. (Proceedings of the Second Annual Genetic Programming Conference, 1997; pp 472-487) is combined in this strategy to optimize the template and map sets obtained. Finally we describe a constructing method that can still produce more sequences by the results obtained in this paper.
Liu
Wenbin
W
Department of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan City 430074, China. wbliu@mail.hust.edu.cn
Wang
Shudong
S
Gao
Lin
L
Zhang
Fengyue
F
Xu
Jin
J
D000465:Algorithms; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D020650:Combinatorial Chemistry Techniques; D019295:Computational Biology; D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry*; D030561:Databases, Nucleic Acid; D015195:Drug Design; D009690:Nucleic Acid Conformation; D017422:Sequence Analysis, DNA; D013698:Templates, Genetic
D004247:DNA