title: Genistein appears to prevent early postmenopausal bone loss as effectively as hormone replacement therapy.
abstract: Recent data from a randomized, double-blind, placebo-controlled, yearlong clinical trial suggest that supplementation with the dietary phytoestrogen genistein (54 mg/day) may be as effective as hormone replacement therapy in attenuating menopause-related bone loss without causing the associated side effects. These findings may have implications for the development of diet-based strategies aimed at osteoporosis prevention.
authors: Department of Food and Nutritional Sciences, University College, Cork, Ireland.
authors: Alice
authors: A
authors: Cotter
authors: Kevin D
authors: KD
authors: Cashman
mesh_terms: D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D015519:Bone Density / Q000187:drug effects; D005260:Female; D019833:Genistein / Q000627:therapeutic use*; D020249:Hormone Replacement Therapy; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D016588:Anticarcinogenic Agents; D019833:Genistein