[Production technology and analysis of blood circulation improving tincture].
This article deals with the production of the tincture of Ginkgo biloba leaves, Crataegus fruits and Leonurus herbs while selecting an extractant, the size of particles in a raw material and possible methods of extraction. The optimal composition of ethanol 70%, the particle size of Ginkgo biloba leaves and Crataegus fruits 2-3 mm of Leonurus herbs. The method of production--percolation, the flow speed 0.5 ml/min. The tincture was analyzed at determination of the sum of flavonoids in terms of quercetin, dry residue, relative density, ethanol concentration. The quality of the tincture was evaluated by high-pressure liquid chromatography and spectrophotometry. The stability of the tincture and its expiry date were fixed.
Bernatoniene
Jurga
J
Faculty of Pharmacy, Kaunas University of Medicine, Kaunas, Lithuania.
Bernatoniene
Rūta
R
Jakstas
Valdas
V
Malinauskas
Faustas
F
Brusokas
Valdemaras
V
D001775:Blood Circulation / Q000187:drug effects*; D002851:Chromatography, High Pressure Liquid; D027825:Crataegus / Q000737:chemistry; D003627:Data Interpretation, Statistical; D005419:Flavonoids / Q000032:analysis* / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry; D020441:Ginkgo biloba / Q000737:chemistry; D006801:Humans; D031332:Leonurus / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011794:Quercetin / Q000032:analysis; D013053:Spectrophotometry
D005419:Flavonoids; D010936:Plant Extracts; D011794:Quercetin