Reperfusion injury of pancreas allografts: relation to islet cell function.
It is unknown to what extent preservation and/or reperfusion may damage islet cells in pancreas allografts. In this study, the release of insulin after reperfusion was used as a marker of injury to the islet cell and compared with the best insulin secretory response (ISR) after glucagon stimulation over a period of 100 days after pancreas transplantation.
Peltenburg
H G
HG
Department of Nephrology and Transplantation, University Hospital Maastricht, Maastricht, The Netherlands.
Wolffenbuttel
B H
BH
Booster
M H
MH
Menheere
P P
PP
Leunissen
K M
KM
Kootstra
G
G
van Hooff
J P
JP
D000328:Adult; D005260:Female; D005934:Glucagon / Q000494:pharmacology; D006084:Graft Rejection / Q000503:physiopathology*; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism*; D016030:Kidney Transplantation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000098:blood supply; D016035:Pancreas Transplantation / Q000473:pathology*; D015427:Reperfusion Injury
D007328:Insulin; D005934:Glucagon