title: [Two advanced gastric cancer patients who showed malignant ileus soon after administration of combination therapy of preoperative intra-peritoneal chemotherapy and gastrectomy].
abstract: Forty-eight patients with serosa-invaded advanced gastric cancer were administered to pre-operative intra-peritoneal chemotherapy to prevent peritoneal recurrence. There were no severe adverse effects from the intra-peritoneal chemotherapy. Of these patients, 2 showed malignant ileus shortly after intra-peritoneal chemotherapy and gastrectomy, and needed laparotomy because of dilatation of duodenum stump and liver dysfunction. The intestines and mesothelium showed diffuse thickness and hardness. We report the clinicopathological features of these cases and therapeutic limitation of intra-peritoneal chemotherapy.
authors: Dept. of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University.
authors: Yoshiyuki
authors: Y
authors: Fujiwara
authors: Hirokazu
authors: H
authors: Taniguchi
authors: Yutaka
authors: Y
authors: Kimura
authors: Shuji
authors: S
authors: Takiguchi
authors: Takushi
authors: T
authors: Yasuda
authors: Masahiko
authors: M
authors: Yano
authors: Morito
authors: M
authors: Monden
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D003131:Combined Modality Therapy; D005743:Gastrectomy; D006801:Humans; D045823:Ileus / Q000209:etiology*; D007274:Injections, Intraperitoneal / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects; D009361:Neoplasm Invasiveness; D011300:Preoperative Care; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D016685:Mitomycin; D002945:Cisplatin