Let's Sco1, Oxidase! Let's Sco!
The solution structure of Sco1 from Bacillus subtilis is the first structure of a protein important in the assembly of cytochrome c oxidase (CcO). The assembly of CcO requires the insertion of multiple cofactors. Sco1 is a conserved protein implicated in formation of the binuclear Cu(A) center.
Winge
Dennis R
DR
Departments of Biochemistry and Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 8413, USA.
D000255:Adenosine Triphosphate / Q000737:chemistry; D020816:Amino Acid Motifs; D001412:Bacillus subtilis / Q000201:enzymology*; D001426:Bacterial Proteins / Q000737:chemistry* / Q000502:physiology; D001665:Binding Sites; D002462:Cell Membrane / Q000378:metabolism; D003300:Copper / Q000737:chemistry; D003545:Cysteine / Q000737:chemistry; D003576:Electron Transport Complex IV / Q000737:chemistry*; D006418:Heme / Q000737:chemistry; D007425:Intracellular Membranes / Q000378:metabolism; D008024:Ligands; D008928:Mitochondria / Q000378:metabolism; D018832:Molecular Chaperones / Q000737:chemistry; D009154:Mutation; D010084:Oxidation-Reduction; D011485:Protein Binding; D017434:Protein Structure, Tertiary
D001426:Bacterial Proteins; D008024:Ligands; D018832:Molecular Chaperones; D006418:Heme; D003300:Copper; D000255:Adenosine Triphosphate; D003576:Electron Transport Complex IV; D003545:Cysteine