title: Distal pancreatectomy: is staple closure beneficial?
abstract: BACKGROUND
  Appropriate closure of the pancreatic remnant after distal pancreatectomy remains controversial. Data on distal pancreatectomy were reviewed to evaluate the effectiveness of staple closure compared with suture closure.
  
  
  METHODS
  Thirty-three patients underwent distal pancreatectomy between January 1994 and December 2001. They were subdivided according to the method of closure of the distal pancreatic stump: the staple group comprised 10 patients and the suture group comprised 23 patients. Charts were reviewed for the method of closure of the distal stump as well as for the serum and urinary amylase level, mortality and morbidity.
  
  
  RESULTS
  In the staple group, no patient developed a pancreatic fistula, whereas in the suture group, eight patients (33.3%) developed a pancreatic fistula (P = 0.0353). The serum amylase level (mean +/- SD) on the first postoperative day was 185 +/- 71 IU/L in the staple group and 499 +/- 461 IU/L in the suture group (P = 0.0413).
  
  
  CONCLUSIONS
  Staple closure by means of a Powered Multifire Endo GIA 60 is a simple, quick and safe alternative to the standard suture closure technique, as it reduces the incidence of pancreatic fistula.
authors: Department of Surgery, Tone Chuo Hospital, and Department of Surgery I, Gunma University School of Medicine, Gunma, Japan. yukinao@dream.ocn.ne.jp
authors: Kunio
authors: K
authors: Takeuchi
authors: Yasushi
authors: Y
authors: Tsuzuki
authors: Tetsu
authors: T
authors: Ando
authors: Masao
authors: M
authors: Sekihara
authors: Takashi
authors: T
authors: Hara
authors: Takayuki
authors: T
authors: Kori
authors: Hiroki
authors: H
authors: Nakajima
authors: Hiroyuki
authors: H
authors: Kuwano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000009:adverse effects* / Q000379:methods*; D010182:Pancreatic Diseases / Q000601:surgery*; D010185:Pancreatic Fistula / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D017792:Surgical Stapling / Q000009:adverse effects / Q000379:methods*; D013536:Suture Techniques / Q000009:adverse effects