title: Molecular interactions in collagen and chitosan blends.
abstract: Molecular interactions between collagen and chitosan (CC) have the potential to produce biocomposites with novel properties. We have characterised the molecular interactions in CC complexes by viscometry, wide angle X-ray scattering and Fourier transform infrared spectroscopy. It was found that CC are miscible at the molecular level and exhibit interactions between the components; X-ray diffraction of CC blends indicate that the collagen helix structure is lost in CC films with increasing chitosan content. Non-linear viscometic behaviour with decreasing chitosan content is interpreted as evidence of a third structural phase formed as a complex of CC. The blending of collagen with chitosan gives the possibility of producing new bespoke materials for potential biomedical applications.
authors: Faculty of Chemistry, N. Copernicus University, 87-100 Torun, Poland.
authors: A
authors: A
authors: Sionkowska
authors: M
authors: M
authors: Wisniewski
authors: J
authors: J
authors: Skopinska
authors: C J
authors: CJ
authors: Kennedy
authors: T J
authors: TJ
authors: Wess
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry*; D002686:Chitin / Q000031:analogs & derivatives* / Q000737:chemistry*; D048271:Chitosan; D003094:Collagen / Q000737:chemistry*; D045424:Complex Mixtures / Q000138:chemical synthesis / Q000737:chemistry*; D046911:Macromolecular Substances; D008420:Manufactured Materials / Q000032:analysis*; D008422:Materials Testing / Q000379:methods*; D008968:Molecular Conformation; D044367:Phase Transition; D014783:Viscosity
chemical_list: D001672:Biocompatible Materials; D045424:Complex Mixtures; D046911:Macromolecular Substances; D002686:Chitin; D003094:Collagen; D048271:Chitosan