[Functional morphology of suprachiasmatic nuclei neurons of rat hypothalamus after the combined influence of x-irradiation and light exposure].
For estimation of light radiomodification and cellular neuroadaptation of the circadian pacemarker, the morphological changes of suprachiasmatic nuclei (SCN) neurons of rat hypothalamus after 48-hours bright light exposure, the single 5 Gy whole-body X-irradiation and their combination were subjected to analysis. The dynamics of reactive and reparative changes has got a phasic character. Temporary desynchronous changes were developed in the course of the early period. Age morphological changes after X-ray and combined irradiation were discovered in the remote period. The plastic diapason of ventrolateral division (SCNv) is more considerable in comparison with dorsomedial division (SCNd). The synergism of X-irradiation and light exposure was discovered in SCNd.
Gerasimov
A V
AV
Siberian State Medical University, Tomsk, 634050 Russia.
D000222:Adaptation, Physiological; D000818:Animals; D002940:Circadian Rhythm; D007031:Hypothalamus / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D008027:Light; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D051381:Rats; D013493:Suprachiasmatic Nucleus / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D013997:Time Factors; D014916:Whole-Body Irradiation