title: Three new structural variants of fetal hemoglobin: Hb F-Campinas [Agamma g121(GH4)Glu --> Gln], Hb F-Paulinia [Ggamma 80(EF4)Asp --> Tyr] and Hb F-Joanopolis [Ggamma73(E17) Asp -->Ala].
abstract: Three new structural variants of fetal hemoglobin were detected in newborns during a neonatal screening for Hb S in the southeast of Brazil: Hb F-Campinas [AgammaI121 (GH4)Glu --> Gln], Hb F-Paulinia [Ggamma80(EF4)Asp -->Tyr] and Hb F-Joanopolis [Ggamma73(E17) Asp -->Ala]. These variants were not related to clinical abnormalities
authors: Denise Faustino
authors: DF
authors: Duarte
authors: Dulcinéia Martins
authors: DM
authors: Albuquerque
authors: Vitoria Regia
authors: VR
authors: Pereira Pinheiro
authors: Fernando
authors: F
authors: Ferreira Costa
authors: Maria
authors: M
authors: De Fátima Sonati
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D003062:Codon / Q000235:genetics; D004252:DNA Mutational Analysis; D005260:Female; D005319:Fetal Hemoglobin / Q000737:chemistry / Q000235:genetics*; D005914:Globins / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008969:Molecular Sequence Data; D020125:Mutation, Missense; D015997:Neonatal Screening; D017354:Point Mutation; D017422:Sequence Analysis, DNA
chemical_list: D003062:Codon; D006455:Hemoglobins, Abnormal; C481800:hemoglobin F Campinas; C481802:hemoglobin F Joanopolis; C481801:hemoglobin F Paulinia; D005914:Globins; D005319:Fetal Hemoglobin