Infections in international pregnancy study: performance of the optical immunoassay test for detection of group B streptococcus.
We evaluated the Strep B optical immunoassay (OIA; ThermoBiostar, Inc.) for detecting light and heavy group B streptococcus colonization in 1,306 pregnant women. The women were examined at 20 to 32 weeks gestation and were from six countries. Compared to culture, the sensitivity and specificity of OIA were 13.3 and 98.4%, respectively, for light colonization and 41.5 and 97.7%, respectively, for heavy colonization.
Thinkhamrop
Jadsada
J
Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Bangkok, Thailand. Jadsada@kku.ac.th
Limpongsanurak
Sompop
S
Festin
Mario R
MR
Daly
Sean
S
Schuchat
Anne
A
Lumbiganon
Pisake
P
Zell
Elizabeth
E
Chipato
Tsungai
T
Win
Aye Aye
AA
Perilla
Mindy J
MJ
Tolosa
Jorge E
JE
Whitney
Cynthia G
CG
D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007494:Ireland / Q000453:epidemiology; D002052:Myanmar / Q000453:epidemiology; D015143:Philadelphia / Q000453:epidemiology; D010679:Philippines / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000453:epidemiology; D015995:Prevalence; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology*; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D015030:Zimbabwe / Q000453:epidemiology