Human cellular inflammation in the pathology of acute cerebral ischaemia.
Leucocytes form important effector pathways for inflammation. This article reviews the clinical evidence for the presence of a cellular inflammatory response in cerebral ischaemia, and attempts to define its temporal profile and spatial distribution. The processes involved in recruitment and activation of leucocytes in this context are addressed, and the successes and failures of interventions aimed at these processes discussed.
Price
C J S
CJ
Department of Medicine, Addenbrooke's Hospital, Cambridge, UK. cp252@medschl.cam.ac.uk
Warburton
E A
EA
Menon
D K
DK
D000208:Acute Disease; D002545:Brain Ischemia / Q000276:immunology* / Q000503:physiopathology*; D015815:Cell Adhesion Molecules / Q000276:immunology / Q000494:pharmacology; D018925:Chemokines / Q000276:immunology / Q000494:pharmacology; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D007962:Leukocytes / Q000276:immunology*
D015815:Cell Adhesion Molecules; D018925:Chemokines