Current status of lipid management of hypertensive patients.
Hypertensives, in addition to requiring strict blood pressure control, need lipid management to prevent cardiovascular disease. To assess the current status of lipid management of hypertensives, we reviewed the profiles of 830 hypertensives. The quality of lipid management was assessed using the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese Adults announced in 1997. Hyperlipidemia was diagnosed in 45.2% of hypertensives and in 56.6% of patients in category C (a group of patients with coronary heart disease). Lipid-lowering drugs were used in 63.5% of all hypercholesterolemic patients and in 78.1% of category C patients. Statins were administered to more than 80% of hypercholesterolemic patients. Only 39.4% of hypertensives achieved the target total cholesterol level and only a very small percentage (17.1%) of patients in category C reached the target levels. The elderly hypertensives were the single largest group (42.2% of all hypertensives) in this study population, and the target cholesterol level for this group has been elevated from 200 mg/dl to 220 mg/dl in the JAS Guidelines for Diagnosis and Treatment of Atherosclerotic Cardiovascular Diseases announced in 2002 (new guidelines). In conclusion, in hypertensives requiring lipid management, the lipid-lowering approach appeared insufficient, as the target achievement rate was relatively low despite a high treatment rate. This was most marked for patients in category C.
Matsubara
Koichi
K
Department of Cardiovascular Medicine, Tottori University Hospital, 36-1 Nishi-machi, Yonago 683-8504, Japan.
Yamamoto
Yasutaka
Y
Sonoyama
Kazuhiko
K
Igawa
Go
G
Furuse
Masako
M
Yatsuhashi
Toru
T
Hamada
Toshihiro
T
Ogino
Kazuhide
K
Igawa
Osamu
O
Hisatome
Ichiro
I
Shigemasa
Chiaki
C
D000368:Aged; D002784:Cholesterol / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000517:prevention & control; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control*; D006973:Hypertension / Q000150:complications*; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016896:Treatment Outcome
D000960:Hypolipidemic Agents; D002784:Cholesterol