Bloodstream isolates of Enterococcus faecium enriched with the enterococcal surface protein gene, esp, show increased adhesion to eukaryotic cells.
Infection-derived Enterococcus faecium strains enriched with esp had increased ability to adhere to Caco-2 cells (P < 0.05) and were less genetically diverse than esp-negative isolates. esp-negative E. faecium fecal isolates from healthy individuals adhered significantly better than esp-negative infection isolates (P < 0.05), indicating additional factors of importance to adhesion.
Lund
Bodil
B
Division of Clinical Bacteriology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden.
Edlund
Charlotta
C
D001426:Bacterial Proteins / Q000097:blood*; D001769:Blood / Q000382:microbiology*; D003110:Colonic Neoplasms; D016984:Enterococcus faecium / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis*; D006801:Humans; D008565:Membrane Proteins / Q000097:blood*; D014407:Tumor Cells, Cultured
D001426:Bacterial Proteins; D008565:Membrane Proteins; C116707:enterococcal surface protein, esp