Chromosomal mapping of the peroneal muscular atrophy (pma) gene in the mouse.
We conducted chromosomal mapping of the pma gene that is a causative gene in the peroneal muscular atrophy mouse, which shows a club foot at birth and unusual gait due to a dropped foot in the adult. Linkage analyses using backcross progeny revealed a significant linkage between the pma gene and three microsatellite markers, D5Mit263 at 73 cM, D5Mit141 and D5Mit97 at 74 cM on Chr 5. The gene order was determined as follows: centromere-D5Mit263-[2.65 cM]-D5Mit141-[2.56 cM]-pma-[5.13 cM]-D5Mit97-telomere.
Katoh
Hideki
H
Institute for Experimental Animals, Hamamatsu University School of Medicine, Handayama, Hamamatsu Shizuoka, Japan.
Watanabe
Yuka
Y
Ebukuro
Michi
M
Muguruma
Kaori
K
Takabayashi
Shuji
S
Shiroishi
Toshihiko
T
D000818:Animals; D002607:Charcot-Marie-Tooth Disease / Q000235:genetics*; D002874:Chromosome Mapping; D005260:Female; D023061:Gene Order / Q000235:genetics; D005808:Genes, Recessive; D008297:Male; D051379:Mice; D008818:Mice, Neurologic Mutants; D018895:Microsatellite Repeats