title: Seasonal and phenological variations of the essential oil from the narrow endemic species Artemisia molinieri and its biological activities.
abstract: The volatile components of the aerial parts of Artemisia molinieri, an endemic wormwood of southern France, were analyzed by GC and GC-MS. Among the 69 compounds identified, major components were ascaridole (19-76%), alpha-terpinene (traces-36%), p-cymene (1-17%), 1,8-cineole (0.3-8%), and germacrene D (0.6-15%). Quantitative variations have been characterized following the season, the phenological cycle, and the aging of the plants. Bioassays have been performed on a sample of essential oil, which has shown a strong inhibition of the growth of both tested yeasts (Candida albicans and Saccharomyces cerevisiae var. chevalieri) and minor activity on both tested Gram-negative bacteria (Escherichia coli and Enterococcus hirae). The oils have shown interesting antioxidant activities on the basis of alpha-tocopherol as reference compound, up to 400-1200%.
authors: Laboratoire Dynamique et Ressources du Végétal, E.A. 2202-Biodiversité, Université de Provence, UFR DENTES et SVTE, case 17, 3 place Victor Hugo, F-13331 Marseille Cedex 3, France. vmasotti@up.univ-mrs.fr
authors: Véronique
authors: V
authors: Masotti
authors: Fabien
authors: F
authors: Juteau
authors: Jean Marie
authors: JM
authors: Bessière
authors: Josette
authors: J
authors: Viano
mesh_terms: D000975:Antioxidants / Q000032:analysis; D019306:Artemisia / Q000737:chemistry*; D002176:Candida albicans / Q000187:drug effects; D002849:Chromatography, Gas; D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols / Q000032:analysis; D000081007:Cymenes; D004926:Escherichia coli / Q000187:drug effects; D000077591:Eucalyptol; D008401:Gas Chromatography-Mass Spectrometry; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry*; D010545:Peroxides / Q000032:analysis; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology; D012621:Seasons; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000975:Antioxidants; D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010545:Peroxides; D010938:Plant Oils; C043372:ascaridole; C007210:4-cymene; C018669:gamma-terpinene; D000077591:Eucalyptol