title: A novel splice variant of human gene GDPD1 is mainly expressed in human ovary and small intestine.
abstract: Glycerophosphodiester phosphodiesterase (GDPD) is a glycerol metabolizing enzyme that has been previously identified in Escherichia coli, Haemophilus influenzae, Bacillus subtilis and Borrelia hermsii. It has been also reported that there is putative protein containing GDPD domain in Mus musculus, but not in Homo sapiens. SMART analysis showed that our predicted protein and three others of the same gene also comprise this domain. Because the gene has not been named, we termed it GDPD1 and accordingly termed our splice variant GDPD1_v1 after acquiring the agreement of HUGO. RT-PCR experiment revealed that our splice variant of the gene is mainly expressed in human ovary and small intestine, basically conforming to the result of serial analysis of gene expression.
authors: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, P.R. China.
authors: Maoqing
authors: M
authors: Wu
authors: Chaoneng
authors: C
authors: Ji
authors: Jian
authors: J
authors: Xu
authors: Xianqiong
authors: X
authors: Zou
authors: Liu
authors: L
authors: Wang
authors: Huarui
authors: H
authors: Zheng
authors: Feng
authors: F
authors: Jin
authors: Yu
authors: Y
authors: Wang
authors: Shaohua
authors: S
authors: Gu
authors: Kang
authors: K
authors: Ying
authors: Yi
authors: Y
authors: Xie
authors: Yumin
authors: Y
authors: Mao
mesh_terms: D017398:Alternative Splicing; D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000378:metabolism*; D008969:Molecular Sequence Data; D010053:Ovary / Q000378:metabolism*; D010727:Phosphoric Diester Hydrolases / Q000096:biosynthesis / Q000235:genetics*; D022821:RNA Splice Sites; D017422:Sequence Analysis, DNA
chemical_list: D022821:RNA Splice Sites; D010727:Phosphoric Diester Hydrolases; C038133:glycerophosphodiester phosphodiesterase