title: Surface modification of poly(dimethylsiloxane) microchannels.
abstract: This review looks at the efforts that are being made to modify the surface of poly(dimethylsiloxane) (PDMS) microchannels, in order to enhance applicability in the field of microfluidics. Many surface modifications of PDMS have been performed for electrophoretic separations, but new modifications are being done for emerging applications such as heterogeneous immunoassays and cell-based bioassays. These new modification techniques are powerful because they impart biospecificity to the microchannel surfaces and reduce protein adsorption. Most of these applications require the use of aqueous or polar solvents, which makes surface modification a very important topic.
authors: National Research Laboratory for Advanced Biotechnology and Biomedical Microinstrumentation, Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.
authors: Honest
authors: H
authors: Makamba
authors: Jin Ho
authors: JH
authors: Kim
authors: Kwanseop
authors: K
authors: Lim
authors: Nokyoung
authors: N
authors: Park
authors: Jong Hoon
authors: JH
authors: Hahn
mesh_terms: D000327:Adsorption; D004129:Dimethylpolysiloxanes; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D008904:Miniaturization / Q000379:methods; D011506:Proteins / Q000032:analysis; D012828:Silicones; D013499:Surface Properties
chemical_list: D004129:Dimethylpolysiloxanes; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D011506:Proteins; D012828:Silicones; C013830:baysilon