Is there an association between skeletal muscle mass and bone mineral density among African-American, Asian-American, and European-American women?
Skeletal muscle strength is a factor in the growth and maintenance of bone density and both skeletal muscle mass and bone mineral density are related to bone fracture risk. We studied the relationship between total body bone mineral density (TBBMD) and total appendicular skeletal muscle mass (TASM) estimated by dual-energy X-ray absorptiometry (DEXA) in African-American (AA), Asian-American (AsA), and European-American (EA) premenopausal (PRM) and postmenopausal (POM) women. The age- and weight-adjusted TBBMD-TASM association was positive in all PRM race groups and in POM EA, but was negative in POM AA and POM AsA. Body weight and age were positively and negatively associated with TBBMD, respectively, and the relationship was stronger in POM. In all race groups the variability in TBBMD was significantly greater in POM women.
Sun
A J
AJ
Obesity Research Center, St Luke's-Roosevelt Hospital Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, USA.
Heshka
S
S
Heymsfield
S B
SB
Wang
J
J
Pierson
R N
RN
Gallagher
D
D
D015502:Absorptiometry, Photon / Q000379:methods; D044466:Asian People; D044383:Black People; D015992:Body Mass Index; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000033:anatomy & histology*; D017698:Postmenopause; D017697:Premenopause; D044469:Racial Groups; D014481:United States; D044465:White People; D001741:Black or African American