title: CDPK-mediated signalling pathways: specificity and cross-talk.
abstract: Plants are constantly exposed to environmental changes and have to integrate a variety of biotic and abiotic stress stimuli. Calcium-dependent protein kinases (CDPKs) are implicated as important sensors of Ca2+ flux in plants in response to these stresses. CDPKs are encoded by multigene families, and expression levels of these genes are spatially and temporally controlled throughout development. In addition, a subset of CDPK genes responds to external stimuli. Biochemical evidence supports the idea that CDPKs are involved in signal transduction during stress conditions. Furthermore, loss-of-function and gain-of-function studies revealed that signalling pathways leading to cold, salt, drought or pathogen resistance are mediated by specific CDPK isoforms
authors: The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK. andrea.ludwig@sainsbury-laboratory.ac.uk
authors: Andrea A
authors: AA
authors: Ludwig
authors: Tina
authors: T
authors: Romeis
authors: Jonathan D G
authors: JD
authors: Jones
mesh_terms: D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics* / Q000502:physiology; D029681:Arabidopsis Proteins / Q000502:physiology; D020868:Gene Silencing; D018745:Genome, Plant; D011494:Protein Kinases / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D017871:Calcium-Calmodulin-Dependent Protein Kinases
chemical_list: D029681:Arabidopsis Proteins; D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases