title: Early nasal continuous positive airway pressure for preterm neonates: the need for randomized trials.
abstract: The use of early nasal continuous positive airway pressure (nCPAP) as prophylaxis and treatment for respiratory distress syndrome in preterm neonates, with or without prophylactic surfactant, is becoming increasingly popular. However, the justification for this is limited to comparisons between centres and comparisons of historical controls.
  
  
  CONCLUSIONS
  Randomized trials and appropriate evaluation of the nCPAP technique are needed.
authors: Department of Neonatology, National University Hospital of Copenhagen, Denmark. klu@rh.dk
authors: K E
authors: KE
authors: Lundstrøm
mesh_terms: D045422:Continuous Positive Airway Pressure / Q000379:methods*; D004864:Equipment and Supplies; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011663:Pulmonary Surfactants / Q000627:therapeutic use; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
chemical_list: D011663:Pulmonary Surfactants