title: Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin.
abstract: N-Acylated ornithine analogues of daptomycin were synthesized and tested for their antibacterial efficacy.
authors: Cubist Pharmaceuticals Inc., 65 Hayden Ave, Lexington, MA 02421, USA.
authors: Jason
authors: J
authors: Hill
authors: James
authors: J
authors: Siedlecki
authors: Ian
authors: I
authors: Parr
authors: Michael
authors: M
authors: Morytko
authors: Xiang
authors: X
authors: Yu
authors: Yanzhi
authors: Y
authors: Zhang
authors: Jared
authors: J
authors: Silverman
authors: Nicole
authors: N
authors: Controneo
authors: Valerie
authors: V
authors: Laganas
authors: Tongchuan
authors: T
authors: Li
authors: Jan-Ji
authors: JJ
authors: Lai
authors: Dennis
authors: D
authors: Keith
authors: George
authors: G
authors: Shimer
authors: John
authors: J
authors: Finn
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D017576:Daptomycin / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice; D008826:Microbial Sensitivity Tests; D009952:Ornithine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D018805:Sepsis / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents; D009952:Ornithine; D017576:Daptomycin