Chemoselectivity of the ruthenium-catalyzed hydrative diyne cyclization: total synthesis of (+)-cylindricine C, D, and E.
[reaction: see text] The chemoselectivity of the ruthenium-catalyzed hydrative diyne cylization is explored in an expeditious synthesis of the tricyclic alkaloids cylindricine C, D, and E.
Trost
Barry M
BM
Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. bmtrost@stanford.edu
Rudd
Michael T
MT
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry*; D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry*; D007536:Isomerism; D015394:Molecular Structure; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
D000470:Alkaloids; D006575:Heterocyclic Compounds, 3-Ring; D015363:Quinolones; C485393:cylindricine E; C485391:cylindricine C; C485392:cylindricine D; D012428:Ruthenium