Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE).
Casciano
I
I
De Ambrosis
A
A
Croce
M
M
Pagnan
G
G
Di Vinci
A
A
Allemanni
G
G
Banelli
B
B
Ponzoni
M
M
Romani
M
M
Ferrini
S
S
D053181:Caspase 8; D020169:Caspases / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000187:drug effects / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D050856:Interferon Regulatory Factor-1; D007372:Interferons / Q000494:pharmacology; D009447:Neuroblastoma / Q000201:enzymology* / Q000235:genetics; D010750:Phosphoproteins / Q000187:drug effects / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D050794:STAT1 Transcription Factor; D015398:Signal Transduction / Q000235:genetics; D015534:Trans-Activators / Q000378:metabolism; D014407:Tumor Cells, Cultured
D004268:DNA-Binding Proteins; C494257:IRF1 protein, human; D050856:Interferon Regulatory Factor-1; D010750:Phosphoproteins; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; D015534:Trans-Activators; D007372:Interferons; C505530:CASP8 protein, human; D053181:Caspase 8; D020169:Caspases