[Cefepime treatment efficacy in surgical patients].
Clinical and bacteriologial efficacies of cefepime were studied in the treatment of 20 surgical patients. Intraoperative prophylaxis is  with the use of cefepime alone and postoperative prophylaxis with the use of cefepime in combination with some other drugs were applied to 10 patients. No postoperative complications in the group of the 10 patients were stated. The other 10 patients were subjected to intraoperative and postoperative combined prophylaxis with some other antibiotics. In 6 patients of the latter group postoperative complications developed. Obvious clinical advantages of cefepime were demonstrated.
Bogomolova
N S
NS
Russian Scientific Centre of Surgery, Russian Academy of Medical Sciences, Moscow.
Oreshkina
T D
TD
Bol'shakov
L V
LV
D019072:Antibiotic Prophylaxis; D001419:Bacteria / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000601:surgery; D000077723:Cefepime; D002511:Cephalosporins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007275:Injections, Intravenous; D007430:Intraoperative Care; D008297:Male; D008826:Microbial Sensitivity Tests; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D014135:Tracheal Stenosis / Q000601:surgery; D016896:Treatment Outcome
D002511:Cephalosporins; D000077723:Cefepime