Are fetal cells in maternal plasma really there? We think they are.
We describe a single centrifugation procedure that resulted in the recovery of fetal cells in maternal blood in 77% of normal male pregnancies and in 87.5% of aneuploid pregnancies. There was an average yield of one fetal cell/1,993 maternal cells in normal pregnancies, which increased to one in 994, in aneuploid pregnancies.
Bayrak-Toydemir
Pınar
P
Reprogenetics Research Inc., Chicago, Illinois, USA. pinbayrak@yahoo.com.|ARUP Laboratories, 500 Chipeta Way, Salt Lake City, Utah, 84108, USA. pinbayrak@yahoo.com.
Pergament
Eugene
E
Reprogenetics Research Inc., Chicago, Illinois, USA.
Fiddler
Morris
M
Reprogenetics Research Inc., Chicago, Illinois, USA.|Depaul University, Chicago, Illinois, USA.
D002498:Centrifugation / Q000379:methods; D005260:Female; D005312:Fetal Blood; D005331:Fetomaternal Transfusion; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*