title: Acute effects of alcohol on auditory thresholds and distortion product otoacoustic emissions in humans.
abstract: OBJECTIVE
  To investigate the acute effects of alcohol consumption on pure-tone thresholds (PTs) and distortion product otoacoustic emissions (DPOAEs) in humans
  
  
  METHODS
  Eight healthy adults were asked to drink alcohol to the clinical intoxication level. PTs and DPOAEs were determined serially before and after alcohol ingestion.
  
  
  RESULTS
  Alcohol had no effect on PTs DPOAE amplitudes above 5500 Hz dropped 30 min and 1 h after alcohol ingestion, returning to the pre-test level 2 h after ingestion.
  
  
  CONCLUSIONS
  In humans, acute alcohol consumption to the intoxication level may cause a temporary reduction in DPOAE amplitudes at high frequencies without affecting auditory thresholds.
authors: Departments of Otolaryngology, Poh-Ai Hospital, I-Lan, Taiwan.
authors: Juen-Haur
authors: JH
authors: Hwang
authors: Ching-Ting
authors: CT
authors: Tan
authors: Ching-Wen
authors: CW
authors: Chiang
authors: Tien-Chen
authors: TC
authors: Liu
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000503:physiopathology; D001309:Auditory Threshold / Q000187:drug effects*; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D018072:Hair Cells, Auditory, Outer / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000187:drug effects*; D010469:Perceptual Distortion / Q000187:drug effects*; D013997:Time Factors
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol