title: Malignant change after 18 months in a lower limb ulcer: acute Marjolin's revisited.
abstract: Lower limb ulcers present a common clinical problem and are at risk of malignant change. A Marjolin's ulcer has traditionally been regarded as malignant change in a long standing ulcer and/or scar tissue. We report a case of Marjolin's degeneration that developed in an ulcer only 18 months following the initial injury. Such a short latent period has not been reported for over 70 years. This report highlights the possibility of early Marjolin's change and we propose a ranked diagnostic screen to aid in early identification of possible malignant change, based on the current published evidence.
authors: Department of Plastic Surgery, George Eliot Hospital NHS Trust, College Street, Nuneaton CV 10 7DJ, UK.
authors: D
authors: D
authors: Thio
authors: J H W
authors: JH
authors: Clarkson
authors: A
authors: A
authors: Misra
authors: S
authors: S
authors: Srivastava
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D006801:Humans; D007871:Leg Ulcer / Q000150:complications*; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology