Pregnancy after limb-sparing hemipelvectomy for Ewing's sarcoma. A case report and review of the literature.
Ewing's sarcoma of the bone is a malignant bone tumor occurring mostly in adolescence and was considered to have poor prognosis. With recent advances in multi-agent combined chemotherapy, prognosis has improved, and more patients with primary lesions in the pelvis opt for limb-saving surgeries. In the present case, Ewing's sarcoma in the left pelvis was diagnosed at the age of 11 and the patient underwent multi-agent chemotherapy combined with limb-sparing hemipelvectomy. She became pregnant at the age of 22. After an uneventful pregnancy, she delivered a healthy child at 37 weeks of gestation by cesarean section because of pelvic distortion. This is the first reported case of pregnancy and delivery after limb-sparing hemipelvectomy due to Ewing's sarcoma. Since the multi-modality treatment improves survival, the number of women with Ewing's sarcoma who desire pregnancy is expected to increase in the future. This is a valuable case that will provide useful information for such patients.
Chihara
Izumi Goto
IG
Department of Obstetrics and Gynecology, Chiba University Hospital, Chiba University School of Medicine, Chiba, Japan.
Osada
Hisao
H
Iitsuka
Yoshinori
Y
Masuda
Kentaro
K
Sekiya
Souei
S
D000328:Adult; D001034:Apgar Score; D001859:Bone Neoplasms / Q000601:surgery*; D002585:Cesarean Section; D005260:Female; D006428:Hemipelvectomy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012512:Sarcoma, Ewing / Q000601:surgery*