title: The use of HSP70 for prevention of consequences of unavoidable stress in rats.
abstract: We studied whether intranasal treatment with HSP70 can be used for the correction of maladaptive behavior in rats after unavoidable stress. After 3 intranasal injection of HSP70 in a dose of 3.25 microg we observed normalization of adaptive behavior after unavoidable stress and improvement of physiological reserves of the organism.
authors: I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg. sts@infran.ru
authors: M A
authors: MA
authors: Flerov
authors: N E
authors: NE
authors: Ordyan
authors: B A
authors: BA
authors: Margulis
authors: I V
authors: IV
authors: Guzhova
authors: A V
authors: AV
authors: V'yushina
authors: S G
authors: SG
authors: Pivina
authors: I A
authors: IA
authors: Gerasimova
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D004558:Electric Stimulation; D018840:HSP70 Heat-Shock Proteins / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D006380:Helplessness, Learned; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013315:Stress, Psychological / Q000188:drug therapy*
chemical_list: D018840:HSP70 Heat-Shock Proteins