[Tamsulosin in the treatment of benign prostatic hyperplasia patients with acute urinary retention].
OBJECTIVE
To evaluate the clinical efficacy of alpha-1 A adrenoceptor antagonist (tamsulosin) in the treatment of benign prostatic hyperplasia (BPH) patients with acute urinary retention.


METHODS
Seventy-two BPH patients with acute retention of urine were randomly divided into treatment group and control group of 36 patients each. All the patients were treated with indwelling catheter, oral antibiotics and the patients in treatment group tamsulosin 0.4 mg once a day for 3 days. The catheter was removed after 72 hours of treatment.


RESULTS
After removal of the catheter, 44% (32/72) of patients voided successfully. The effect rates were 61% (22/36) in the tamsulosin treatment group and 28% (10/36) in the control group(P < 0.01).


CONCLUSIONS
Treatment with tamsulosin was effective in raising the success rate of voiding without catheter after an episode of acute urinary retention. The efficacy of treatment was not influenced by the volume of prostate.
Hua
Li-Xin
LX
Department of Urology, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Wu
Hong-Fei
HF
Sui
Yuan-Geng
YG
Chen
Shuang-Guan
SG
Xu
Zheng-Quan
ZQ
Zhang
Wei
W
Qian
Li-Xin
LX
D000208:Acute Disease; D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications / Q000188:drug therapy*; D013449:Sulfonamides / Q000008:administration & dosage / Q000627:therapeutic use*; D000077409:Tamsulosin; D016896:Treatment Outcome; D014546:Urinary Catheterization; D016055:Urinary Retention / Q000150:complications / Q000188:drug therapy*
D000317:Adrenergic alpha-Antagonists; D013449:Sulfonamides; D000077409:Tamsulosin