Biologic gels in tissue engineering.
There are many different types of scaffold materials now available for tissue engineering applications. Hydrogels form one group of materials that have been used in a wide variety of applications. These hydrogels can be formed using natural materials, synthetic materials, or some combination of the two. There are advantages and disadvantages to using each type of material, and detailed investigations into the effects on various aspects of cell behavior of chemical and physical properties of the materials are needed to make an informed decision as to which material is best suited for a given application. By combining appropriate scaffold materials, such as hydrogels, with cells and proper signaling for those cells, more commercial tissue engineering products will become available for general use.
Mann
Brenda K
BK
Keck Graduate Institute, 535 Watson Drive, Claremont, CA 91711, USA. bmann@kgi.edu
D001672:Biocompatible Materials / Q000627:therapeutic use*; D005109:Extracellular Matrix / Q000502:physiology; D005782:Gels / Q000627:therapeutic use*; D006801:Humans; D020100:Hydrogels / Q000627:therapeutic use; D011108:Polymers / Q000627:therapeutic use; D023822:Tissue Engineering / Q000379:methods*
D001672:Biocompatible Materials; D005782:Gels; D020100:Hydrogels; D011108:Polymers