title: Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, Botswana.
abstract: To exclude tuberculosis, WHO/UNAIDS recommends considering medical history, symptom screen, and chest radiograph before starting tuberculosis prevention in people infected with HIV. The value of a chest radiograph for this purpose is unknown. We prospectively assessed 935 HIV-infected outpatients seeking isoniazid preventive therapy. Of 935 patients, 692 (74%) had no signs or symptoms of tuberculosis. Of these 692, 123 (18%) were lost during the chest radiograph process, and one (0.2%) of the remaining 563 was diagnosed with tuberculosis on the basis of the chest radiograph. A screening chest radiograph should not be required routinely for asymptomatic people taking isoniazid as preventive treatment in settings able to screen for signs and symptoms of tuberculosis.
authors: BOTUSA Project, US Centers for Disease Control and Prevention, Gaborone, Botswana. baru1@cdc.gov
authors: B
authors: B
authors: Mosimaneotsile
authors: E A
authors: EA
authors: Talbot
authors: T L
authors: TL
authors: Moeti
authors: N M
authors: NM
authors: Hone
authors: G
authors: G
authors: Moalosi
authors: H J
authors: HJ
authors: Moffat
authors: E J
authors: EJ
authors: Lee
authors: T A
authors: TA
authors: Kenyon
mesh_terms: D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001902:Botswana / Q000453:epidemiology; D015897:Comorbidity; D005069:Evaluation Studies as Topic; D005260:Female; D015658:HIV Infections / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008400:Mass Chest X-Ray / Q000706:statistics & numerical data; D008875:Middle Aged; D010865:Pilot Projects; D011314:Preventive Health Services; D011446:Prospective Studies; D013902:Radiography, Thoracic / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000517:prevention & control*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid