title: Photoreception in Neurospora: a tale of two White Collar proteins.
abstract: Neurospora crassa is the best-understood fungal organism in terms of the mechanism of light responses. All known Neurospora photoresponses are mediated by blue light. Two Per-Arnt-Simdomain containing transcription factors, WHITE COLLAR-1 (WC-1) and WC-2, are essential components for almost all light responses. Recently, WC-1was shown to be a blue-light photoreceptor. How light affects the DNA binding of the WC proteins to the promoter of the circadian clock gene frequency was also demonstrated. These studies established a mechanism that explains the light responses mediated by activation of transcription. The purpose of this review is to summarize the findings of recent studies on the molecular mechanism of photoreception in Neurospora.
authors: Department of Physiology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9040, USA. yi.liu@UTsouthwestern.edu
authors: Y
authors: Y
authors: Liu
authors: Q
authors: Q
authors: He
authors: P
authors: P
authors: Cheng
mesh_terms: D004268:DNA-Binding Proteins / Q000502:physiology*; D005656:Fungal Proteins / Q000235:genetics; D015966:Gene Expression Regulation, Fungal / Q000502:physiology; D009491:Neurospora / Q000502:physiology*; D010786:Photoreceptor Cells / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*
chemical_list: D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D014157:Transcription Factors; C423283:VVD protein, Neurospora crassa; C105589:wc-1 protein, Neurospora crassa; C103772:white collar 2 protein, Neurospora