Current problems of prostate cancer.
Metastatic prostate cancer is primarily treated by endocrine manipulation. Complete androgen blockade with analogue of luteinizing hormone releasing hormone (LHRH) or surgical castration and antiandrogens seem to have no advantage over the LHRH analogues or surgical castration alone. The progression to a hormone-refractory state is still a challenging issue for urologists because of the lack of standard therapy.
Goncalves
F
F
Department of Urology, Faculty ofMedicine, Comenius University, Derer's Memorial Hospital, Bratislava, Slovakia. bll@fmed.uniba.sk
Hornak
M
M
Ondrus
D
D
Miklosi
M
M
Kotula
V
V
D000368:Aged; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000628:therapy*