Synthesis and hierarchical self-assembly of cavity-containing facial amphiphiles.
The synthesis and aggregation behavior of cavity-containing facial amphiphiles is described. The molecules consist of a glycoluril-based rigid cavity functionalized with two water-soluble benzoate groups. By specific molecular recognition processes in water, the amphiphilic hosts self-assemble in a hierarchical process to form arrays of molecules. Depending on the counterions, these arrays can be assembled into well-defined aggregates of mesoscopic size. The size and shape of the aggregates can be tuned by variations in the size and substitution pattern of the cavities of the host molecules.
Elemans
Johannes A A W
JA
Department of Organic Chemistry, NSRIM institute, University of Nijmegen, Toernooiveld, 6525 ED Nijmegen, The Netherlands. jelemans@sci.kun.nl
Slangen
Ralf R J
RR
Rowan
Alan E
AE
Nolte
Roeland J M
RJ