title: Minimising the risk of prion transmission by contact tonometry.
abstract: OBJECTIVE
  The unknown prevalence of variant Creutzfeldt-Jakob disease (vCJD) in the UK population has led to fears of horizontal transmission through routine medical procedures. The potential risk of transmission via contact tonometry was examined.
  
  
  METHODS
  The total amount of protein carried over by tonometer tips after applanation of patients was assessed.
  
  
  RESULTS
  Tonometer tips had an inherent ability to carry proteinaceous material. There was a large variability in the load carried over between individual patients. Rinsing tonometer tips in water reduced protein carryover. Wiping the tonometer tips also reduced carriage, though less dramatically.
  
  
  CONCLUSIONS
  There is a small theoretical risk of transmission of vCJD by contact tonometry through reuse, but this should be reduced if the prisms are washed and wiped. In the light of these findings a protocol for the management of reusable tonometer prisms is recommended.
authors: Institute of Ophthalmology, Department of Pathology, Bath Street, London EC1V 9EL, UK.
authors: S Z
authors: SZ
authors: Amin
authors: L
authors: L
authors: Smith
authors: P J
authors: PJ
authors: Luthert
authors: M E
authors: ME
authors: Cheetham
authors: R J
authors: RJ
authors: Buckley
mesh_terms: D003666:Decontamination / Q000379:methods*; D018562:Disease Transmission, Infectious; D004209:Disposable Equipment; D004866:Equipment Contamination; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D017096:Prion Diseases / Q000517:prevention & control* / Q000635:transmission