title: Recurrent pneumococcal meningitis in a splenectomised HIV-infected patient.
abstract: BACKGROUND
  Streptococcus pneumoniae is a major cause of human disease, especially in pre-school children and elderly people, as well as in special risk groups such as asplenic, antibody deficient patients, or presenting disruption of natural barriers. The occurrence of pneumococcal disease has increased with the onset of the HIV epidemic and the emergence of drug-resistance.
  
  
  METHODS
  We report the case of an HIV-1-infected patient who experienced three episodes of recurrent pneumococcal meningitis over a 4-year period, despite chemoprophylaxis and capsular vaccination.
  
  
  CONCLUSIONS
  Efficacy of anti-pneumococcal chemoprophylaxis and vaccination in HIV-infected patients are discussed in the light of this particular case.
authors: Laboratoire de Microbiologie; Hôpital Necker-Enfants Malades, 149 rue de Sèvres 75743 Paris Cedex 15, France. morand@mpiib-berlin.mpg.de
authors: Philippe C
authors: PC
authors: Morand
authors: Veronique
authors: V
authors: Veuillez
authors: Claire
authors: C
authors: Poyart
authors: Eric
authors: E
authors: Abachin
authors: Gilles
authors: G
authors: Quesne
authors: Bertrand
authors: B
authors: Dupont
authors: Patrick
authors: P
authors: Berche
authors: Jean-Paul
authors: JP
authors: Viard