title: [Metallophilia in the Ranvier's nodes of nerve fibers in rats of different strains (histochemical study)].
abstract: Myelinated nerve fibers formed by the processes of LV spinal ganglion neurons were studied in two lines of rats selected according to high and low thresholds of nerve system excitability to electric current. Before ultrastructural study the fibres have been treated with potassium pyroantimonate. It was demonstrated that specific dense precipitate was deposited in the nodes of Ranvier of the nerve fibers of rats with low excitability thresholds; this precipitate was not found in the fibers of rats with high thresholds. It is suggested that deposition of precipitate is indicative of a high density of sodium channels in neurilemma, i.e. of high functional activity of nerve fibers.
authors: Laboratory of Regulation of Brain Neurons Functions, Laboratory of Functional Neuromorphology and Neuron Physiology, Laboratory of Genetics of Higher Nervous Activity, RAS I.P. Pavlov Institute of Physiology, St. Petersburg.
authors: V V
authors: VV
authors: Vshivtseva
authors: I N
authors: IN
authors: Zamuraev
authors: V G
authors: VG
authors: Lukashin
authors: N V
authors: NV
authors: Shiriaeva
mesh_terms: D000818:Animals; D002412:Cations; D005727:Ganglia, Spinal / Q000378:metabolism* / Q000648:ultrastructure; D007150:Immunohistochemistry; D008297:Male; D008670:Metals / Q000378:metabolism*; D008854:Microscopy, Electron; D009441:Neurilemma / Q000378:metabolism / Q000648:ultrastructure; D011901:Ranvier's Nodes / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D015222:Sodium Channels / Q000378:metabolism; D013315:Stress, Psychological / Q000378:metabolism* / Q000473:pathology
chemical_list: D002412:Cations; D008670:Metals; D015222:Sodium Channels