Cyclization of alpha-Oxo-oximes to 2-substituted benzoxazoles.
Reactions of oximes 9, 17, and 19 with electrophiles 15a-f and 24 in the presence of anhydrous potassium carbonate or triethylamine give 2-substituted condensed ring oxazoles 10, 16a-c, 18a-d, 20a-c, and 25 in a new general route to these compounds.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
Wang
Zuoquan
Z
Hall
C Dennis
CD
Akhmedov
Novruz G
NG
Shestopalov
Aleksandr A
AA
Steel
Peter J
PJ