[Outcome of repeated epididymal sperm aspiration or testicular sperm extraction in azoospermic patients].
OBJECTIVE
To review the outcome of repeated percutaneous sperm aspiration (PESA) and testicular sperm extraction (TESE) for intracytoplasmic sperm injection (ICSI).


METHODS
Forty-three cycles of 31 cases of azoospermic patients which underwent at least two PESA or TESE for ICSI from January 2001 to December 2002 were collected. The sperm retrieval, fertilization, implantation and clinical pregnancy were analyzed.


RESULTS
Twenty-four cases underwent PESA and 7 cases underwent TESE. There were not any complications in these patients. Compared with the first cycle of 154 cases, the fertilization rate, implantation rate and clinical pregnancy rate were 78.39% vs 73.64%, 19.68% vs 18.38% and 34.88% vs 37.91%, respectively(P > 0.05).


CONCLUSIONS
Repeated PESA or TESE is safe and well tolerated in azoospermic patients. Compared with the first cycle, the differences of repeated PESA or TESE cycles in fertilization rate, implantation rate and clinical pregnancy rate were not statistically significant.
Ou
Jian-Ping
JP
Reproductive Medicine Research Center, Affiliated 1st Hospital, Zhongshan University, Guangzhou, Guangdong 510080, China.
Zhuang
Guang-Lun
GL
Zhou
Can-Quan
CQ
Wang
Chang-Xi
CX
Zhan
Qian-Sheng
QS
Fang
Cong
C
Shu
Yi-Min
YM
Peng
Wen-Lin
WL
Zhang
Min-Fang
MF
D000328:Adult; D053713:Azoospermia / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D020858:Tissue and Organ Harvesting / Q000379:methods*