(-)-FR182877 is a potent and selective inhibitor of carboxylesterase-1.
Adam
Gregory C
GC
The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Vanderwal
Christopher D
CD
Sorensen
Erik J
EJ
Cravatt
Benjamin F
BF
D043182:Carboxylesterase / Q000037:antagonists & inhibitors*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D011083:Polycyclic Compounds / Q000494:pharmacology*
D004791:Enzyme Inhibitors; C408303:FR 182877; D011083:Polycyclic Compounds; D043182:Carboxylesterase