title: N-nitration of secondary amines with 4-chloro-5-methoxy-2-nitropyridazin-3-one.
abstract: N-Nitration of 4-chloro-5-substituted-pyridazin-3-one with copper nitrate trihydrate in acetic anhydride gave the corresponding 4-chloro-2-nitro-5-substituted-pyridazin-3-one. 4-Chloro-5-alkoxy-2-nitropyridazin-3-ones such as 5-methoxy (2b) and 5-ethoxy (2d) derivatives showed excellent nitro group transfer potentiality. N-Nitration of some secondary amines with 2b gave the corresponding N-nitramines under mild neutral condition in good yields.
authors: Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Chinju 660-701, Korea.
authors: Young-Dae
authors: YD
authors: Park
authors: Ho-Kyun
authors: HK
authors: Kim
authors: Jeum-Jong
authors: JJ
authors: Kim
authors: Su-Dong
authors: SD
authors: Cho
authors: Sung-Kyu
authors: SK
authors: Kim
authors: Motoo
authors: M
authors: Shiro
authors: Yong-Jin
authors: YJ
authors: Yoon