title: Supplementing with beta-hydroxy-beta-methylbutyrate (HMB) to build and maintain muscle mass: a review.
abstract: Beta-hydroxy-beta-methylbutyrate, more commonly referred to as HMB, is derived from the amino acid, leucine, and its keto acid, alpha-ketoisocaproate. In several studies combining HMB supplementation and resistance exercise, researchers have concluded that HMB may play an important role in reducing protein degradation and/or increasing recovery of damaged muscle cells. These actions could be advantageous to all individuals participating in exercise programs and improve the lives of many by overcoming weakness or frailty.
authors: Department of Physiology, Medicine and Pathology, Georgetown University Medical Center, Washington, DC 20057, USA.
authors: Tal
authors: T
authors: Alon
authors: Debasis
authors: D
authors: Bagchi
authors: Harry G
authors: HG
authors: Preuss
mesh_terms: D015444:Exercise; D006801:Humans; D006868:Hydrolysis; D009124:Muscle Proteins / Q000378:metabolism; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D014631:Valerates / Q000008:administration & dosage*
chemical_list: D009124:Muscle Proteins; D014631:Valerates; C004961:beta-hydroxyisovaleric acid