Phaeochromocytoma unmasked by drug therapy.
(1) Phaeochromocytoma is a benign or malignant tumour that stores and produces catecholamines (adrenaline and noradrenaline, and their metabolites metanephrine and normetanephrine). (2) Phaeochromocytoma can be unmasked by some drugs. (3) Metoclopramide and other neuroleptics are most often implicated. Other drugs include antidepressants (such as selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, and imipramine), betablockers, opioids, and curare.
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D000319:Adrenergic beta-Antagonists / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008787:Metoclopramide / Q000009:adverse effects*; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects; D009294:Narcotics / Q000009:adverse effects; D010673:Pheochromocytoma / Q000175:diagnosis*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects
D000319:Adrenergic beta-Antagonists; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D008787:Metoclopramide; D008996:Monoamine Oxidase Inhibitors; D009294:Narcotics; D017367:Selective Serotonin Reuptake Inhibitors