title: Complex segmental elbow reconstruction after tumor resection.
abstract: Twenty-three patients were reviewed retrospectively to determine their oncologic and functional outcomes after resection of 15 primary or eight metastatic tumors about the elbow between 1985 and 2000. The indications for resection were dictated by the histologic features of the tumor, location of the lesion, and extent of bone destruction. A total humeral reconstruction was done in 12 patients. Of this group, an endoprosthesis was used in seven patients and a total humeral allograft with a proximal humeral prosthesis and osteoarticular elbow reconstruction (allograft-prosthetic composite) was used in five patients. Eleven additional patients had a segmental total elbow replacement after resection of the distal humerus or proximal ulna. Local disease control was achieved in 17 patients (74%). Fourteen patients presented with (48%) or had (13%) distant metastasis develop, but only eight (35%) died of their disease. Periprosthetic lysis or allograft resorption was present in five patients (22%), and two (18%) humeral components of total elbow prostheses required revision for loosening. The mean Musculoskeletal Tumor Society functional score was 23 of 30 points (77%) in the 12 living patients followed up for a mean of 46 months (range, 24-124 months). It was 83% in patients with a segmental total elbow reconstruction and 71% in patients with a total humeral reconstruction. Aggressive limb salvage of the humerus or elbow or both provides a satisfactory functional outcome without jeopardizing overall survival.
authors: University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. kweber@mdanderson.org
authors: Kristy L
authors: KL
authors: Weber
authors: Patrick P
authors: PP
authors: Lin
authors: Alan W
authors: AW
authors: Yasko
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D019643:Arthroplasty, Replacement / Q000009:adverse effects / Q000379:methods*; D001859:Bone Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D002292:Carcinoma, Renal Cell / Q000601:surgery; D004551:Elbow Joint; D005260:Female; D018737:Hand Strength; D006801:Humans; D006811:Humerus; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000601:surgery; D010027:Osteotomy; D018579:Patient Selection; D011475:Prosthesis Failure; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000009:adverse effects / Q000379:methods*; D016019:Survival Analysis; D014184:Transplantation, Homologous; D016896:Treatment Outcome