title: [Williams syndrome: memory, visuospatial and visuoconstructive functions].
abstract: BACKGROUND
  Williams syndrome (WS) is a dominant autosomal genetic syndrome resulting from a microdeletion on chromosome 7. This deletion gives rise to certain characteristic physical traits, systemic pathologies and a cognitive behavioural pattern that is characterised by the relative preservation of linguistic abilities with very striking visuospatial deficits.
  
  
  METHODS
  We describe the neuropsychological features of three patients with WS, diagnosed by means of a cytogenetic study, and their mnemonic functions and visuospatial skills are explored.
  
  
  CONCLUSIONS
  The results obtained in the study of these three patients reinforce the idea, already acknowledged in the literature, of the marked visuospatial difficulties. They also account for the need for an early diagnosis and an extensive knowledge of the cognitive profile of these patients so as to allow the planning of a stimulation that strengthens the cognitive possibilities of children suffering from this syndrome as much as possible.
authors: Unitat de Neuropediatria, Hospital de Sabadell, Corporació Sanitaria Parc Taulí, Sabadell, Barcelona, España. kats@arrakis.es
authors: C
authors: C
authors: García-Nonell
authors: E
authors: E
authors: Rigau-Ratera
authors: J
authors: J
authors: Artigas-Pallarés
authors: C
authors: C
authors: García-Sánchez
authors: A
authors: A
authors: Estévez-González
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology; D008297:Male; D008569:Memory Disorders / Q000209:etiology; D009483:Neuropsychological Tests; D011597:Psychomotor Performance; D013037:Spatial Behavior; D018980:Williams Syndrome / Q000150:complications / Q000523:psychology* / Q000628:therapy