Pregnancy in kidney recipients under cyclosporine.
About 1 of every 50 women of child-bearing age who have a functioning kidney transplant become pregnant. Successful pregnancies following kidney allotransplantation with conventional immunosuppressive treatment are well described, and there is no evidence of abnormalities in the infants born. The use of cyclosporine (CSA) means new problems for the pregnant women and the fetus: the risk of congenital abnormalities, fetal growth retardation, hepato- and nephrotoxicity. We report the experience of 16 pregnancies in 16 of our kidney transplant patients, of which 7 were treated with CSA.
Berardinelli
L
L
Department of Vascular Surgery and Kidney Transplantation, Policlinico University Hospital, Milan, Italy.
Dallatana
R
R
Beretta
C
C
Raiteri
M
M
Tonello
G
G
Quaglia
F
F
Vegeto
A
A
D001379:Azathioprine / Q000627:therapeutic use; D001724:Birth Weight; D003404:Creatinine / Q000097:blood; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D016030:Kidney Transplantation / Q000276:immunology / Q000502:physiology*; D008598:Menstruation / Q000502:physiology; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011256:Pregnancy Outcome
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D003404:Creatinine; D001379:Azathioprine; D011241:Prednisone