Successful twin pregnancy in panhypopituitarism caused by suprasellar germinoma.
BACKGROUND
Pregnancy in a woman with hypopituitarism from a suprasellar germinoma is rare.


METHODS
A 27-year-old woman presented with panhypopituitarism from a suprasellar germinoma. She had diabetes insipidus, hypothyroidism, adrenal cortex dysfunction, and hypogonadotropic ovarian failure. When treated with thyroxin, cortisol, antidiuretic hormone, human menopausal gonadotropin, and human chorionic gonadotropin, she conceived and gave birth to healthy twins.


CONCLUSIONS
Hormonal replacement therapy and ovulation induction resulted in a successful pregnancy in a woman with panhypopituitarism.
Kitajima
Yoshimitsu
Y
Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Endo
Toshiaki
T
Yamazaki
Kiyohiro
K
Hayashi
Takuhiro
T
Kudo
Ryuichi
R
D000328:Adult; D003919:Diabetes Insipidus / Q000209:etiology; D005260:Female; D018237:Germinoma / Q000150:complications / Q000628:therapy*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology / Q000628:therapy*; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D010911:Pituitary Neoplasms / Q000150:complications / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy*; D011272:Pregnancy, Multiple; D012658:Sella Turcica; D014427:Twins