title: Incidence of the mucopolysaccharidoses in Western Australia.
abstract: An epidemiological study of the mucopolysaccharidoses in Western Australia (WA) using multiple ascertainment sources was carried out and the incidence rate for the period 1969-1996 was estimated. An incidence of approximately 1 in 107,000 live births was obtained for MPS IH (Hurler phenotype); 1 in 320,000 live births (1 in 165,000 male live births) for MPS II (Hunter Syndrome); 1 in 58,000 for MPS III (Sanfilippo Syndrome); 1 in 640,000 for MPS IVA (Morquio Syndrome type A), and 1 in 320,000 for MPS VI (Maroteaux-Lamy Syndrome). The overall incidence for all types of mucopolysaccharidosis was approximately 1 in 29,000 live births. A comparison is made with incidence estimates obtained from other published studies.
authors: Genetic Services of Western Australia, King Edward Memorial Hospital for Women, Perth, Australia. John.Nelson@health.wa.gov.au
authors: John
authors: J
authors: Nelson
authors: June
authors: J
authors: Crowhurst
authors: Bill
authors: B
authors: Carey
authors: Lawrence
authors: L
authors: Greed
mesh_terms: D005260:Female; D005838:Genotype; D006801:Humans; D015994:Incidence; D008297:Male; D009083:Mucopolysaccharidoses / Q000145:classification / Q000453:epidemiology* / Q000235:genetics; D014904:Western Australia / Q000453:epidemiology