title: Successful management of severe chylothorax with argon plasma fulguration and fibrin glue in a premature infant.
abstract: Post-traumatic neonatal chylothorax is a rare entity. Management includes medical and surgical treatment. We describe here a newborn who developed a severe chylothorax after repair of an oesophageal atresia. The chylothorax was treated successfully by a combination of argon beam coagulation of the mediastinum and fibrin glue application. However, the patient developed complete thrombosis of the left femoral vein with clot extension to the inferior vena cava which resolved after infusion of recombinant tissue plasminogen activator (rt-PA). The use of argon plasma coagulation and mediastinal fibrin glue application for treating postoperative chylothorax appears to be attractive and is easy to perform even in small premature infants and may replace a more extensive surgical procedure. However, the coagulation profile should be monitored and special care should be taken to prevent vascular thrombosis after surgery.
authors: Department of Neonatology, Jeanne de Flandre Hospital, CHRU Lille, Lille, France.
authors: N
authors: N
authors: Rifai
authors: R
authors: R
authors: Sfeir
authors: T
authors: T
authors: Rakza
authors: J
authors: J
authors: Alameh
authors: R
authors: R
authors: Besson
authors: P
authors: P
authors: Lequien
authors: L
authors: L
authors: Storme
mesh_terms: D001128:Argon; D002916:Chylothorax / Q000209:etiology / Q000601:surgery*; D004564:Electrocoagulation; D004933:Esophageal Atresia / Q000601:surgery; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D006831:Polyhydramnios; D011182:Postoperative Care; D011183:Postoperative Complications / Q000601:surgery; D011247:Pregnancy; D013908:Thoracotomy; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D001128:Argon