title: Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners.
abstract: OBJECTIVE
  Studies demonstrating reduced quality of life and psychological well-being in multiple sclerosis (MS) have typically investigated patients within more advanced stages of disease. The aim of the present paper was to evaluate the emotional burden and quality of life of recently diagnosed MS patients and their partners.
  
  
  METHODS
  Data on health-related quality of life (SF-36), anxiety and depression (Hospital Anxiety and Depression Scale) and disease-related distress (Impact of Event Scale) were obtained in 101 patients and their partners (n=78).
  
  
  RESULTS
  On average 8 months after diagnosis (range 0-24 months), 34% of the patients and 40% of the partners had clinically high levels of anxiety, and 36% of the patients and 24% of the partners had levels of severe distress. Scores of anxiety, depression and distress were higher in patients with more functional limitations (Expanded Disability Status Scale=3.0). Quality of life was significantly poorer in patients compared with controls, particularly among those with higher disability.
  
  
  CONCLUSIONS
  Both patients and their partners demonstrated high levels of anxiety and distress in the early period after the diagnosis. These findings indicate careful attention by health care professionals to identify those who may benefit from further psychological support.
authors: Department of Neurology, Erasmus MC, Rotterdam, The Netherlands.
authors: A C J W
authors: AC
authors: Janssens
authors: P A
authors: PA
authors: van Doorn
authors: J B
authors: JB
authors: de Boer
authors: F G A
authors: FG
authors: van der Meché
authors: J
authors: J
authors: Passchier
authors: R Q
authors: RQ
authors: Hintzen
mesh_terms: D000328:Adult; D001007:Anxiety / Q000209:etiology*; D003625:Data Collection; D003863:Depression / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications / Q000523:psychology*; D011788:Quality of Life; D018454:Spouses / Q000523:psychology*; D013315:Stress, Psychological