title: Acute appendicitis with fulminant necrotizing fasciitis in a neonate.
abstract: The authors report on a neonate who presented with acute appendicitis and who went on to have fatal necrotizing fasciitis. Although recognized in adults, this rare combination of conditions has not been reported previously in the neonate and requires rapid recognition with aggressive medical and surgical intervention.
authors: Division of Neonatology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
authors: Abhay
authors: A
authors: Lodha
authors: Paul W
authors: PW
authors: Wales
authors: Andrew
authors: A
authors: James
authors: Charles R
authors: CR
authors: Smith
authors: Jacob C
authors: JC
authors: Langer
mesh_terms: D000208:Acute Disease; D001062:Appendectomy; D001064:Appendicitis / Q000150:complications* / Q000382:microbiology / Q000601:surgery; D002981:Clindamycin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000302:isolation & purification; D019115:Fasciitis, Necrotizing / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D017809:Fatal Outcome; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy; D041121:Klebsiella oxytoca / Q000302:isolation & purification; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D011183:Postoperative Complications; D012772:Shock, Septic / Q000188:drug therapy / Q000209:etiology; D013203:Staphylococcal Infections / Q000150:complications / Q000188:drug therapy
chemical_list: D010406:Penicillins; D008795:Metronidazole; D002981:Clindamycin