title: Pathogenesis of murine cytomegalovirus infection.
abstract: Infection of mice with murine cytomegalovirus (MCMV) is an established model for studying human cytomegalovirus (HCMV) infection. Similarly to HCMV infection, pathological changes and disease manifestations during MCMV infection are mainly dependent on the immune status of the mouse host. This review focuses mainly on the pathogenesis of MCMV infection in immunocompetent and immunodeficient and/or immature mice and discusses the principles of immunosurveillance of infection and the mechanisms by which this virus evades immune control.
authors: Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, B. Branchetta 20, 51000 Rijeka, Croatia. astridk@medri.hr
authors: Astrid
authors: A
authors: Krmpotic
authors: Ivan
authors: I
authors: Bubic
authors: Bojan
authors: B
authors: Polic
authors: Pero
authors: P
authors: Lucin
authors: Stipan
authors: S
authors: Jonjic
mesh_terms: D000818:Animals; D003587:Cytomegalovirus / Q000302:isolation & purification / Q000472:pathogenicity* / Q000502:physiology; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000276:immunology* / Q000503:physiopathology; D004195:Disease Models, Animal; D006801:Humans