A forehead mass present for 53 years after trauma in childhood.
A 60-year-old man developed a mass on his forehead in his childhood. Histologic examination revealed a subcutaneous encapsulated cellular neoplasm consisting of mostly polygonal epithelioid cells, with abundant amphophilic cytoplasm and pleomorphic nuclei. There was one focal area of spindle cells. Numerous blood vessels of various sizes, small vacuoles and eosinophilic hyalinized material were also present. The morphologic features of the neoplasm did not fit with the typical features of any recognized pathologic entity. The subsequent immunohistochemical and electron microscopical evidence supported the diagnosis of epithelioid schwannoma, a rare variant of schwannoma that has not been reported in oral and maxillofacial pathology publications. The purpose of this report is to document a case and increase the awareness of this entity.
Cheng
Yi-Shing Lisa
YS
Diagnostic Sciences, Baylor College of Dentistry-Texas A & M University System Health Science Center, Dallas, TX 75246, USA. ycheng@tambcd.edu
Binnie
William
W
Shroyer
John
J
Bridges
George
G
D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000473:pathology*; D005546:Forehead / Q000293:injuries / Q000473:pathology*; D006801:Humans; D006818:Hyalin / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D014617:Vacuoles / Q000648:ultrastructure