Giant keratoacanthoma arising in hypertrophic lichen planus.
A 45-year-old man presented with a rapidly enlarging tumour in an area of long-standing hypertrophic lichen planus of the lower leg. Histological examination of the resected specimen showed it to be a giant keratoacanthoma measuring 37 x 57 mm. Neoplastic change is a rarely reported complication of chronic variants of cutaneous lichen planus. To date there have been only two reports of keratoacanthoma development in association with lichen planus.
Giesecke
Leah M
LM
Department of Dermatology, Royal Adelaide Hospital and Adelaide Pathology Partners, Adelaide, South Australia, Australia. leah_giesecke@hotmail.com
Reid
Catherine M
CM
James
Craig L
CL
Huilgol
Shyamala C
SC
D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D007150:Immunohistochemistry; D007636:Keratoacanthoma / Q000473:pathology*; D008010:Lichen Planus / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome