title: [Evaluation of arterial infusion chemotherapy for liver metastasis from gastric cancer].
abstract: We evaluated the effectiveness of arterial infusion chemotherapy for liver metastasis from gastric cancer. Nineteen patients (9 synchronous cases, 10 metachronous cases) were treated with hepatic arterial infusion chemotherapy (HAIC). The response rate was 26% (CR 3, PR 2, PD 14), and the median survival time was 357 days after the diagnosis of liver metastasis. The treatment was discontinued in 8 patients because of treatment associated complications and disease progression. Absence of extrahepatic lesion, response of HAIC, and hepatectomy did not improve the prognosis. The combination of systemic chemotherapy with HAIC tended to improve the prognosis. It may be necessary to reevaluate HAIC as a treatment modality for liver metastasis from gastric cancer.
authors: Dept. of Surgery, Osaka National Hospital.
authors: Atsushi
authors: A
authors: Takeno
authors: Kazumasa
authors: K
authors: Fujitani
authors: Toshimasa
authors: T
authors: Tsujinaka
authors: Motohiro
authors: M
authors: Hirao
authors: Yutaka
authors: Y
authors: Takeda
authors: Masaki
authors: M
authors: Kashiwazaki
authors: Hideyuki
authors: H
authors: Mishima
authors: Masakazu
authors: M
authors: Ikenaga
authors: Toshiro
authors: T
authors: Sawamura
authors: Yasunori
authors: Y
authors: Hasuike
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009378:Neoplasms, Multiple Primary; D016609:Neoplasms, Second Primary; D013274:Stomach Neoplasms / Q000473:pathology*; D015996:Survival Rate
chemical_list: D016685:Mitomycin; D002945:Cisplatin; D005472:Fluorouracil