Prenatal diagnosis and management of fetal anemia secondary to a large chorioangioma.
BACKGROUND
Chorioangiomas are benign vascular tumors of the placenta. Complications occur when their size exceeds 5 cm.


METHODS
We report the use of peak systolic velocity in the middle cerebral artery, fetal hemoglobin levels in maternal circulation, and maternal serum alpha-fetoprotein levels in the diagnosis and management of fetal anemia in a patient with a large placental chorioangioma.


CONCLUSIONS
Fetal hemoglobin levels in maternal circulation and abrupt elevations of middle cerebral artery peak velocity may be useful in detecting fetal anemia.
Hamill
Neil
N
Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.
Rijhsinghani
Asha
A
Williamson
Roger A
RA
Grant
Stanley
S
D000328:Adult; D000740:Anemia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D001783:Blood Flow Velocity; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005319:Fetal Hemoglobin / Q000032:analysis; D006391:Hemangioma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D010922:Placenta Diseases / Q000150:complications* / Q000175:diagnosis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis; D011296:Prenatal Diagnosis; D018608:Ultrasonography, Doppler; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D005319:Fetal Hemoglobin