A large fibrous polyp of the gallbladder mimicking a polypoid carcinoma.
Fibrous polyp of the gallbladder is a rare variant of benign gallbladder polyp. Differentiation between a benign polyp and polypoid carcinoma of the gallbladder is often difficult when the polyp is more than 1 cm in diameter. We report a rare case of a large fibrous polyp of the gallbladder mimicking a carcinoma. A 44-year-old Korean woman who presented with abdominal pain was diagnosed with a large gallbladder polyp, measuring 1.26 cm in diameter, by abdominal ultrasonography. The lesion was echogenic with a nodular surface on ultrasonography, and showed contrast enhancement on computed tomography. Neither evidence of infiltration into the gallbladder wall nor lymph node enlargement was shown. The resected gallbladder showed a 1.2 x 0.8-cm-sized polyp with a nodular surface. Histologically, it showed a leaf-like configuration and loose or cellular connective stroma containing scattered duct-like structures, varying-sized vessels, and patchy infiltration of chronic inflammatory cells. Stromal cells were immunoreactive for vimentin and smooth-muscle actin and negative for S-100 protein and desmin. Large fibrous polyps of the gallbladder should be considered in the differential diagnosis of benign and malignant polypoid lesions of the gallbladder.
Kim
Dong Hoon
DH
Department of Pathology, Sungkyunkwan University School of Medicine, Samsung Medical Center, 50 Irwon-dong, Gangnam-gu, 135-710, Seoul, Korea.
Kim
Seong Rim
SR
Song
Sang Yong
SY
Lee
Jong Kyun
JK
Heo
Jinseok
J
Kim
Seung Hoon
SH
D000328:Adult; D017081:Cholecystectomy, Laparoscopic; D003937:Diagnosis, Differential; D005260:Female; D005355:Fibrosis; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000473:pathology*; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D011127:Polyps / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional