Prevalence of arterial hypertension following kidney transplantation--a multifactorial analysis.
Arterial hypertension is one of the most important factors leading to chronic graft nephropathy and causing cardiovascular complications following renal transplantation. Effective control of the blood pressure seems to be vital for satisfactory long-term graft and patient survival. The objective of the study was to evaluate possible factors associated with persistent or de novo hypertension in patients following allogenic cadaveric kidney transplantation. 325 patients with minimum follow-up period of 6 months and only on cyclosporine-based immunosuppression were analyzed. Two groups of patients were compared: group A included normotensive or "well controlled hypertension" patients while group B consisted of patients with uncontrolled hypertension. Results revealed that patients with ill-controlled or uncontrolled hypertension received kidneys from older donors, mean creatinine level within 6 months post-transplant was significantly higher and hypertension was associated with higher rate of urinary tract infections in this group.
Włodarczyk
Z
Z
Department of Transplantation and General Surgery, Medical University, Bydgoszcz. zwlodar@yahoo.co.uk
Glyda
M
M
Kościanska
L
L
Kołodziejczyk
J
J
Sulikowska
B
B
Manitius
J
J
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002102:Cadaver; D003404:Creatinine / Q000097:blood; D016572:Cyclosporine / Q000097:blood / Q000627:therapeutic use; D005163:Factor Analysis, Statistical; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000502:physiology; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors; D017211:Treatment Failure; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000453:epidemiology
D007166:Immunosuppressive Agents; D008055:Lipids; D016572:Cyclosporine; D003404:Creatinine