title: Open-access gastroscopy is associated with improved outcomes in gastric cancer.
abstract: OBJECTIVE
  To examine whether patients with gastric cancer diagnosed via open-access gastroscopy (OAG) differ in their outcomes compared with patients referred conventionally to outpatient clinics or as acute emergencies.
  
  
  METHODS
  Prospective observational study in the gastroenterology and surgical units of a large district general hospital.
  
  
  METHODS
  One hundred consecutive patients with gastric adenocarcinoma.
  
  
  METHODS
  Data were collected prospectively and subdivided into two groups according to whether the patients were referred via the open-access route or the conventional route.
  
  
  RESULTS
  Diagnostic delay from onset of symptoms was shorter for patients referred via OAG compared with those referred conventionally. Stages of disease were significantly earlier in patients referred via OAG compared with patients referred conventionally. Potentially curative resection was significantly more likely following OAG than after conventional referral. Cumulative five-year survival for patients referred via OAG was 30% compared with 12% after conventional outpatient referral and 13% after acute referral. Multivariate analysis revealed three factors to be associated with survival: stage of disease, distant metastases and referral via the open-access route.
  
  
  CONCLUSIONS
  Gastric cancers presenting at OAG were diagnosed at an earlier stage than cancers diagnosed after conventional referral. This led to a higher proportion of potentially curative resections and better five-year survival.
authors: Departments of Surgery and Gastroenterology, Royal Gwent Hospital, Newport, UK.
authors: Guy R
authors: GR
authors: Blackshaw
authors: Jonathan D
authors: JD
authors: Barry
authors: Paul
authors: P
authors: Edwards
authors: Miles C
authors: MC
authors: Allison
authors: Wyn G
authors: WG
authors: Lewis
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004812:Epidemiologic Methods; D005260:Female; D005773:Gastroscopy / Q000379:methods*; D006297:Health Services Accessibility; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D012017:Referral and Consultation / Q000458:organization & administration*; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D014852:Wales