Myocardial preservation with the UW solution. First European results in clinical heart transplantation.
In recent years, there is a growing body of evidence that the University of Wisconsin (UW) solution offers many advantages in organ preservation with regard to preservation quality and time. We, therefore, conducted the first European prospective, randomized, clinical trial comparing myocardial performance after preservation with UW and St. Thomas Hospital (ST) solution. Preliminary results indicated superior heart function after preservation with UW solution.
Demertzis
S
S
Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Federal Republic of Germany.
Wahlers
T
T
Schäfers
H J
HJ
Wippermann
J
J
Jurmann
M
M
Cremer
J
J
Haverich
A
A
D000241:Adenosine / Q000494:pharmacology*; D000328:Adult; D000493:Allopurinol / Q000494:pharmacology*; D001639:Bicarbonates / Q000494:pharmacology; D002122:Calcium Chloride / Q000494:pharmacology; D002314:Cardioplegic Solutions / Q000494:pharmacology; D005060:Europe; D005978:Glutathione / Q000494:pharmacology*; D006321:Heart; D016027:Heart Transplantation / Q000379:methods / Q000502:physiology*; D006439:Hemodynamics; D006801:Humans; D007328:Insulin / Q000494:pharmacology*; D008274:Magnesium / Q000494:pharmacology; D019188:Organ Preservation Solutions; D011189:Potassium Chloride / Q000494:pharmacology; D011887:Raffinose / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology; D014655:Vascular Resistance
D001639:Bicarbonates; D002314:Cardioplegic Solutions; D007328:Insulin; D019188:Organ Preservation Solutions; C041711:St. Thomas' Hospital cardioplegic solution; C055206:University of Wisconsin-lactobionate solution; D012965:Sodium Chloride; D000493:Allopurinol; D011189:Potassium Chloride; D005978:Glutathione; D008274:Magnesium; D000241:Adenosine; D002122:Calcium Chloride; D011887:Raffinose