Detangling Alzheimer's disease.
Alzheimer's disease (AD) afflicts 4 million people in the United States and is expected to strike 14 million by the year 2050, as the population ages. Researchers are scrambling to find genetic risk factors, decipher disease mechanisms, and develop reliable diagnostic tests that detect the illness at its earliest, potentially most treatable stage. Using these findings, they hope to devise new therapeutic approaches. Current clinical trials are testing novel techniques that stall or reverse AD-like neuropathology in mice.
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D000544:Alzheimer Disease / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D000818:Animals; D006801:Humans