title: Infective endocarditis due to Neisseria meningitidis: two case reports.
abstract: Two cases of meningococcal endocarditis are described. An 84-year-old man developed sepsis and septic shock and died 15 h after admission to the department. The autopsy revealed aortic endocarditis. Blood and vegetation culture yielded Neisseria meningitidis B:16:P1.5. A 37-year-old man was admitted for fever and rash lasting several weeks. Endocarditis of the bicuspid aortic valve caused by N. meningitidis C:2a:P1.2,5 was found. The patient was successfully treated with penicillin G for 4 weeks. Brief epidemiologic characteristics of invasive meningococcal disease in the Czech Republic are given.
authors: Department of Infectious Diseases, 3rd Faculty of Medicine, Bulovka University Hospital, Budinova 2, 180 81 Prague, Czech Republic. benesj@cesnet.cz
authors: J
authors: J
authors: Benes
authors: O
authors: O
authors: Dzupova
authors: M
authors: M
authors: Kabelkova
authors: P
authors: P
authors: Krizova
authors: A
authors: A
authors: Gabrielova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D009345:Neisseria meningitidis / Q000302:isolation & purification*
chemical_list: D000890:Anti-Infective Agents