The National Eye Institute of The National Institutes of Health: its history and impact on clinical eye care.
BACKGROUND
Research supported by the National Eye Institute (NEI) of the National Institutes of Health (NIH) has contributed to the visual well being of the world. Pertinent citations from the literature were compiled to produce a clinical database reviewing major studies of the NEI and their outcomes.


METHODS
Using Internet search engines and library resources, clinical NEI studies were reviewed. Their purpose, description, outcome and clinical importance are summarized.


RESULTS
The results of major clinical NEI research are presented and included are the current modalities of treatment for each disease studied.


CONCLUSIONS
Each NEI study yielded results upon which current scientific guidelines for the treatment or prevention of ocular disease are based.
Gurwood
Andrew S
AS
The Eye Institute, Philadelphia, Pennsylvania 19141, USA. agurwood@pco.edu
D035843:Biomedical Research; D003695:Delivery of Health Care; D005128:Eye Diseases / Q000517:prevention & control*; D006291:Health Policy; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009316:National Institutes of Health (U.S.) / Q000266:history* / Q000458:organization & administration*; D009885:Ophthalmology / Q000266:history* / Q000458:organization & administration*; D017410:Practice Guidelines as Topic; D012109:Research Support as Topic; D014481:United States