title: Microrheology of entangled F-actin solutions.
abstract: We measure the viscoelasticity of entangled F-actin over length scales between 1 and 100 microm using one- and two-particle microrheology, and directly identify two distinct microscopic contributions to the elasticity. Filament entanglements lead to a frequency-independent elastic modulus over an extended frequency range of 0.01-30 rad/sec; this is probed with one-particle microrheology. Longitudinal fluctuations of the filaments increase the elastic modulus between 0.1 and 30 rad/sec at length scales up to the filament persistence length; this is probed by two-particle microrheology.
authors: Department of Physics & DEAS, Harvard University, Cambridge, Massachusetts 02138, USA.
authors: M L
authors: ML
authors: Gardel
authors: M T
authors: MT
authors: Valentine
authors: J C
authors: JC
authors: Crocker
authors: A R
authors: AR
authors: Bausch
authors: D A
authors: DA
authors: Weitz
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry; D000199:Actins / Q000737:chemistry*; D004548:Elasticity; D012212:Rheology / Q000379:methods; D012996:Solutions; D014783:Viscosity
chemical_list: D000199:Actins; D012996:Solutions