title: Prenatal diagnosis and management of fetal anemia secondary to a large chorioangioma.
abstract: BACKGROUND
  Chorioangiomas are benign vascular tumors of the placenta. Complications occur when their size exceeds 5 cm.
  
  
  METHODS
  We report the use of peak systolic velocity in the middle cerebral artery, fetal hemoglobin levels in maternal circulation, and maternal serum alpha-fetoprotein levels in the diagnosis and management of fetal anemia in a patient with a large placental chorioangioma.
  
  
  CONCLUSIONS
  Fetal hemoglobin levels in maternal circulation and abrupt elevations of middle cerebral artery peak velocity may be useful in detecting fetal anemia.
authors: Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.
authors: Neil
authors: N
authors: Hamill
authors: Asha
authors: A
authors: Rijhsinghani
authors: Roger A
authors: RA
authors: Williamson
authors: Stanley
authors: S
authors: Grant
mesh_terms: D000328:Adult; D000740:Anemia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D001783:Blood Flow Velocity; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005319:Fetal Hemoglobin / Q000032:analysis; D006391:Hemangioma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D010922:Placenta Diseases / Q000150:complications* / Q000175:diagnosis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis; D011296:Prenatal Diagnosis; D018608:Ultrasonography, Doppler; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins; D005319:Fetal Hemoglobin