title: Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus.
abstract: The location of elastase in rat uterus during its postpartum involution was studied by electron histochemical method. Intense extracellular activity of the enzyme was detected: the reaction product was found on the cytolemma of smooth-muscle cells and, to a lesser extent, on the cytolemma of macrophages and fibroblasts and on adjacent collagen fibrils. The reaction product was also found in vacuoles with collagen in macrophages and fibroblasts.
authors: Laboratory of Morphology, Nicolae Testemitsiany State University of Medicine and Pharmaceutics of Republic of Moldova, Kishinev.
authors: V V
authors: VV
authors: Ryvnyak
authors: O F
authors: OF
authors: Dulgieru
mesh_terms: D000818:Animals; D003094:Collagen / Q000378:metabolism*; D005260:Female; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D008264:Macrophages / Q000378:metabolism / Q000648:ultrastructure; D010196:Pancreatic Elastase / Q000378:metabolism*; D049590:Postpartum Period; D011247:Pregnancy; D051381:Rats; D014599:Uterus / Q000201:enzymology* / Q000502:physiology / Q000648:ultrastructure
chemical_list: D003094:Collagen; D010196:Pancreatic Elastase