Changes of AFPmRNA in blood after percutaneous ethanol injection treatment of hepatocellular carcinoma.
OBJECTIVE
To study the effects of percutaneous ethanol injection (PEI) in treatment of hepatocellular carcinoma (HCC).


METHODS
Blood samples were taken from 9 HCC patients and detected by nested RT-PCR to find out AFPmRNA after PEI treatment 3-5 times within 2 weeks.


RESULTS
Three (44.44%) of 4 patients with AFPmRNA positive turned to be negative after PEI treatment and 1 with AFPmRNA positive (11.11%) lasted within 2 weeks.


CONCLUSIONS
PEI may diminish the possibility of distant metastasis of HCC.
Liu
Yang
Y
Institute of East Hepatobiliary Surgery, Second Military Medical University, Shanghai 200348, China. liuyang@smmu.edu.cn
Wu
Meng-Chao
MC
Qian
Guang-Xiang
GX
Zhang
Bai-He
BH
D000279:Administration, Cutaneous; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000378:metabolism*; D000431:Ethanol / Q000008:administration & dosage*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000097:blood*; D000509:alpha-Fetoproteins / Q000235:genetics*
D012333:RNA, Messenger; D000509:alpha-Fetoproteins; D000431:Ethanol