title: [Prospective study of systemic inflammatory response syndrome of patients with nosocomial G- bacteria infection].
abstract: OBJECTIVE
  To study the characteristics of systemic inflammatory response syndrome (SIRS) of inpatients with nosocomial G- bacteria infection in order to find on effective treatment.
  
  
  METHODS
  Eighty-two inpatients of SIRS with lower respiratory tract infection with G- bacteria were studied prospectively until discharge or death. They were divided into two groups: observation group (42 cases) and control group (40 cases). Bacteria culture of sputum and drug sensitivity was performed. Routine treatment was carried out in the control group, and rhubarb and antibiotics with lower endotoxin releasing property were given to the observation group. The course of SIRS, the incidence of MODS, and the mortality were compared.
  
  
  RESULTS
  The duration with SIRS in observation group and control group was respectively (6.2+/-1.3) days and (7.4+/-1.2) days, u=3.91, P<0.05; the incidence of MODS was 11.4 percent and 32.3 percent, respectively, chi(2)=4.27, P<0.05. The mortality rates of the patients with SIRS in two groups were 8.6 percent and 29.0 percent, respectively.
  
  
  CONCLUSIONS
  The results indicated that the treatment with rhubarb could obviously reduce the duration of SIRS compared with routine method. The same is true in the incidence of MODS and mortality rate.
authors: Lanzhou Medical College Second Affiliated Hospital, Lanzhou Emergency Centre, Lanzhou 730030, Gansu, China.
authors: Chen-ming
authors: CM
authors: Dong
authors: Jian-xiong
authors: JX
authors: Zhao
authors: Pei-jie
authors: PJ
authors: Li
authors: Lan
authors: L
authors: Yang
authors: Tian-ping
authors: TP
authors: Niu
authors: Tian-duo
authors: TD
authors: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000453:epidemiology; D011446:Prospective Studies; D018746:Systemic Inflammatory Response Syndrome / Q000188:drug therapy / Q000401:mortality*