[Involvement of the optic nerve in the course of Behcet's disease (presentation of 148 cases)].
Behçet's disease is a multisystemic vascularitis of still unknown etiopathogeny. Among 400 cases of Behçet disease, 148 cases presented an optic nerve involvement during a period of eight years (1992-1999). The goal of this work is to contribute to the study of optic nerve involvement in Behçet's disease. The involvement is higher in males (64%) with median age of 27 years. The involvement of the optic nerve is noticed in 37% of cases. It's isolated in 7% of cases and occurs on average after 5 years of evolution of the disease. The diagnosis is based on the clinical examination, visual field, visual evoked potentials, retinal angiography and neuro-imaging (TDM and/or MRI). It can be an acute anterior neuropathy, stasis papilledema complicating a benign intracranial hypertension, neuroretinitis or retrobulbar optic neuropathy. The extraocular systemic manifestations were dominated by oral aphthosis (94%), genital aphthosis (70%), joint manifestations (40%) and central nervous system involvement (32.4%). The prognosis is reserved, 44% of patients having vision lower than 1/10 in spite of treatment. The authors insist on the therapeutic emergency that this involvement represents and the interest to consider it in all patients having an unexplained visual loss.
Lamari
H
H
Service d'Ophtalmologie Pédiatrique-Hôpital 20 Août-Casablanca-Maroc.
Baha
Ali T
AT
Benhaddou
M
M
Alikane
O
O
Hamdani
M
M
Zaghloul
K
K
Amraoui
A
A
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001528:Behcet Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D001530:Belgium / Q000453:epidemiology; D015897:Comorbidity; D005074:Evoked Potentials, Visual; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000453:epidemiology*; D017678:Sex Distribution; D014792:Visual Acuity