title: Successful twin pregnancy in panhypopituitarism caused by suprasellar germinoma.
abstract: BACKGROUND
  Pregnancy in a woman with hypopituitarism from a suprasellar germinoma is rare.
  
  
  METHODS
  A 27-year-old woman presented with panhypopituitarism from a suprasellar germinoma. She had diabetes insipidus, hypothyroidism, adrenal cortex dysfunction, and hypogonadotropic ovarian failure. When treated with thyroxin, cortisol, antidiuretic hormone, human menopausal gonadotropin, and human chorionic gonadotropin, she conceived and gave birth to healthy twins.
  
  
  CONCLUSIONS
  Hormonal replacement therapy and ovulation induction resulted in a successful pregnancy in a woman with panhypopituitarism.
authors: Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan.
authors: Yoshimitsu
authors: Y
authors: Kitajima
authors: Toshiaki
authors: T
authors: Endo
authors: Kiyohiro
authors: K
authors: Yamazaki
authors: Takuhiro
authors: T
authors: Hayashi
authors: Ryuichi
authors: R
authors: Kudo
mesh_terms: D000328:Adult; D003919:Diabetes Insipidus / Q000209:etiology; D005260:Female; D018237:Germinoma / Q000150:complications / Q000628:therapy*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology / Q000628:therapy*; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D010911:Pituitary Neoplasms / Q000150:complications / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy*; D011272:Pregnancy, Multiple; D012658:Sella Turcica; D014427:Twins