title: [Inflammatory pseudo-tumor of the liver: is pre-operative diagnosis possible?].
abstract: Inflammatory pseudo-tumors of the liver are rare and difficult to diagnose, mimicking malignant tumors.
  
  
  OBJECTIVE
  To specify the circumstances of detection and the clinical, biological, radiological and pathological features of inflammatory pseudo-tumors, in order to improve preoperative diagnosis.
  
  
  METHODS
  Diagnosis of inflammatory pseudo-tumors of the liver was performed on surgical specimens in 8 patients from January 1987 to January 2001. We retrospectively analyzed the clinical, biological, radiological and pathological features of these 8 inflammatory pseudo-tumors.
  
  
  RESULTS
  All the patients (5 females and 3 males) presented a chronic infectious syndrome and/or previous history of chronic inflammatory disease. The correlation between biological, radiological and pathological aspects showed two distinctive types of inflammatory pseudo-tumors: a type revealed by a biological inflammatory syndrome, with a non encapsulated, heterogeneous and hypervascular lesion at imaging, and a dense fibroblastic inflammatory pseudo-tumor with portal endophlebitis on histology (n=5), and a type without inflammatory syndrome, with an encapsulated, homogeneous, hypovascular lesion at imaging and abundant necrosis on histology (n=3).
  
  
  CONCLUSIONS
  The analysis of previous history, of clinical, biological and radiological presentations, specially MRI, could predict the diagnosis of inflammatory lesion which must be confirmed by trans-parietal biopsy to avoid inappropriate radical hepatectomy.
authors: Service d'Anatomie Pathologique, Hôpital Beaujon, Clichy.
authors: Adjé
authors: A
authors: Abbey-Toby
authors: Dominique
authors: D
authors: Cazals-Hatem
authors: Magali
authors: M
authors: Colombat
authors: Jacques
authors: J
authors: Belghiti
authors: Valérie
authors: V
authors: Vilgrain
authors: Claude
authors: C
authors: Degott
mesh_terms: D000328:Adult; D005260:Female; D006104:Granuloma, Plasma Cell / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012189:Retrospective Studies