Application of external microwave thermotherapy in urology: past, present, and future.
The excellent clinical results of transurethral microwave thermotherapy (TUMT) for the treatment of symptomatic benign prostatic hyperplasia (BPH) gave to TUMT the leading position among the microwave thermotherapy modalities available for the treatment of different urologic conditions. Research in TUMT has focused on operating software, temperature monitoring, intraprostatic heat distribution, cell-kill calculations, and correlations with clinical variables. Randomized comparisons of TUMT with other established therapies for BPH, including transurethral resection, have facilitated the evaluation of the clinical outcome, durability, morbidity, and costs of the treatment. The applications of microwave thermotherapy in other urologic diseases are also presented in this review.
Gravas
Stavros
S
Department of Urology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Laguna
M Pilar
MP
De La Rosette
Jean J M C H
JJ
D001291:Attitude of Health Personnel; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D018579:Patient Selection; D011237:Predictive Value of Tests; D011470:Prostatic Hyperplasia / Q000601:surgery*; D012106:Research; D020728:Transurethral Resection of Prostate / Q000191:economics / Q000379:methods* / Q000639:trends; D016896:Treatment Outcome; D014563:Urodynamics / Q000528:radiation effects; D014565:Urogenital Neoplasms / Q000532:radiotherapy*