Nitroalkanes in aqueous medium as an efficient and eco-friendly source for the one-pot synthesis of 1,4-diketones, 1,4-diols, delta-nitroalkanols, and hydroxytetrahydrofurans.
The Michael addition of primary aliphatic nitro compounds to alpha,beta-unsaturated enones, performed in aqueous media, provides the one-pot synthesis of 1,4-diketones, 1,4-diols, delta-nitroalkanols, and hydroxytetrahydrofurans, respectively, by the appropriate choice of the reaction conditions.
Ballini
Roberto
R
Dipartimento di Scienze Chimiche dell'Università di Camerino, Via S. Agostino 1, 62032 Camerino, Italy. roberto.ballini@unicam.it
Barboni
Luciano
L
Giarlo
Guido
G