Target-selective ion-exchange media for highly hydrophilic compounds: a possible solution by use of the "interval immobilization technique".
We prepared a crosslinked polymer as a separation and/or adsorption medium for CYN, as shown in Fig. 1. The polymers were evaluated by high-performance liquid chromatography (HPLC) and adsorption was examined under batch conditions. Results from detailed HPLC evaluation and measurement of the difference between the binding affinity for CYN and for other compounds showed the prepared polymer had specific recognition ability for CYN.
Kubo
Takuya
T
Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
Tanaka
Nobuo
N
Hosoya
Ken
K
D000470:Alkaloids; D001427:Bacterial Toxins; D001665:Binding Sites; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange / Q000295:instrumentation* / Q000379:methods*; D000087522:Cyanobacteria Toxins; D057927:Hydrophobic and Hydrophilic Interactions; D007475:Ion Exchange Resins / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D012996:Solutions; D013379:Substrate Specificity; D013499:Surface Properties; D014498:Uracil / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification*
D000470:Alkaloids; D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; D007475:Ion Exchange Resins; D011108:Polymers; D012996:Solutions; C089595:cylindrospermopsin; D014498:Uracil