Reference values for stationary and 24-hour ambulatory esophageal manometry and pH data in Hispanic population.
BACKGROUND
It has not yet been determined whether values obtained with stationary esophageal motility test are similar to those obtained with the 24-h procedure. Furthermore, there are no normal values established for esophageal pH and motility parameters in a Hispanic population.


METHODS
Reflux symptoms, endoscopy, Helicobacter pylori, stationary esophageal manometry, and combined 24-h pH-manometry were evaluated in 12 healthy volunteers. Three subjects also underwent 24-h esophageal bilirubin monitoring.


RESULTS
Mean lower esophageal sphincter pressure measured stationary was lower (p<0.05) compared with 24-h ambulatory procedure. Mean duration of contraction waves was greater with stationary method (p<0.05). Esophageal contraction mean amplitude was not different between both procedures. Total percent of time with pH<4 was 0.16+/-0.21. Total 24-h acid reflux episodes were 5.5+/-6.6, with no episodes >5 min. No high bilirubin reflux episodes were recorded.


CONCLUSIONS
These results suggested that physiologic motility parameters differed depending on the method employed for its evaluation. Values obtained with stationary and 24-h ambulatory esophageal manometry are identical when evaluating amplitude of contractions but differ in duration of contractions and lower esophageal sphincter pressure. In addition, these results provide for the first time reference values for stationary and 24-h ambulatory esophageal manometry and pH data in a Hispanic population.
Awad
Richard A
RA
Sección Esofácica Unidad de Medicina Experimental y de Motilidad, Hospital General de México, Secretaría de Salud (SSA), Mexico City, Mexico. awadrichard@iserve.net.mx
Camacho
Santiago
S
D000328:Adult; D001663:Bilirubin / Q000378:metabolism; D004947:Esophagus / Q000378:metabolism / Q000502:physiology*; D016480:Helicobacter pylori / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry / Q000379:methods*; D008800:Mexico; D018670:Monitoring, Ambulatory; D012016:Reference Values
D001663:Bilirubin