agr-dependent bacterial interference has no impact on long-term colonization of Staphylococcus aureus during persistent airway infection of cystic fibrosis patients.
The agr specificity group distribution of persistent Staphylococcus aureus clones recovered from the airways of cystic fibrosis (CF) patients did not differ from that of isolates recovered from various clinical infections and healthy nasal carriers. The success of CF clones in terms of cocolonization and/or infection with S. aureus, prevalence of clones, or persistence appeared to be independent of agr group specificity.
Kahl
Barbara C
BC
Institute of Medical of Microbiology. Institute for Hygiene, University of Muenster, Muenster 48149, Germany. kahl@uni-muenster.de
Becker
Karsten
K
Friedrich
Alexander W
AW
Clasen
Julia
J
Sinha
Bhanu
B
Von Eiff
Christof
C
Peters
Georg
G
D000898:Antibiosis / Q000502:physiology*; D001426:Bacterial Proteins / Q000032:analysis*; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications*; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D013203:Staphylococcal Infections / Q000503:physiopathology*; D013211:Staphylococcus aureus / Q000254:growth & development*; D013997:Time Factors; D015534:Trans-Activators / Q000032:analysis*
C095698:Agr protein, Staphylococcus aureus; D001426:Bacterial Proteins; D015534:Trans-Activators