title: Pregnancy after limb-sparing hemipelvectomy for Ewing's sarcoma. A case report and review of the literature.
abstract: Ewing's sarcoma of the bone is a malignant bone tumor occurring mostly in adolescence and was considered to have poor prognosis. With recent advances in multi-agent combined chemotherapy, prognosis has improved, and more patients with primary lesions in the pelvis opt for limb-saving surgeries. In the present case, Ewing's sarcoma in the left pelvis was diagnosed at the age of 11 and the patient underwent multi-agent chemotherapy combined with limb-sparing hemipelvectomy. She became pregnant at the age of 22. After an uneventful pregnancy, she delivered a healthy child at 37 weeks of gestation by cesarean section because of pelvic distortion. This is the first reported case of pregnancy and delivery after limb-sparing hemipelvectomy due to Ewing's sarcoma. Since the multi-modality treatment improves survival, the number of women with Ewing's sarcoma who desire pregnancy is expected to increase in the future. This is a valuable case that will provide useful information for such patients.
authors: Department of Obstetrics and Gynecology, Chiba University Hospital, Chiba University School of Medicine, Chiba, Japan.
authors: Izumi Goto
authors: IG
authors: Chihara
authors: Hisao
authors: H
authors: Osada
authors: Yoshinori
authors: Y
authors: Iitsuka
authors: Kentaro
authors: K
authors: Masuda
authors: Souei
authors: S
authors: Sekiya
mesh_terms: D000328:Adult; D001034:Apgar Score; D001859:Bone Neoplasms / Q000601:surgery*; D002585:Cesarean Section; D005260:Female; D006428:Hemipelvectomy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012512:Sarcoma, Ewing / Q000601:surgery*