MenoPAUSE: taking a second look at the role of HRT.
HRT should not be used for prevention of cardiovascular and coronary artery disease. While estrogen plays a role in osteoporosis, the bisphosphonates and raloxifene demonstrate equal or superior efficacy for prevention and treatment, compared with HRT. HRT decreases the risk of colon cancer but increases a woman's chance of developing breast cancer. Short-term use of low-dose HRT remains a valid option for management of menopausal symptoms, especially hot flushes. Pharmacists can help patients interpret the information in the press and guide them in weighing the risks and benefits as they evaluate HRT for use in their own individual situations.
Takiya
Liza
L
Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, USA.
Umland
Elena
E
D001943:Breast Neoplasms / Q000139:chemically induced; D002318:Cardiovascular Diseases / Q000517:prevention & control; D003110:Colonic Neoplasms / Q000517:prevention & control; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008593:Menopause; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control