title: Callus formation and cucurbitacin B accumulation in Ecballium elaterium callus cultures.
abstract: Ecballium elaterium fruit juice is used for the treatment of sinusitis in Turkish folk medicine. The aim of this study was to increase the yield of cucurbitacin B, an anti-inflammatory compound previously isolated in various organs of E. elaterium, through tissue culture techniques. Higher yields of cucurbitacin B (1.126%) were obtained from the first subculture calluses from stem nodes in the presence of benzyl adenine (BA; 1 mg/l) and naphtalene acetic acid (NAA; 0.1 mg/l) in comparison with the yields obtained from plant material (0.01%).
authors: Gazi University, Faculty of Pharmacy, Etiler, Ankara 06330, Turkey. gulnur@gazi.edu.tr
authors: G
authors: G
authors: Toker
authors: M
authors: M
authors: Memişoğlu
authors: M C
authors: MC
authors: Toker
authors: E
authors: E
authors: Yeşilada
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism*; D002478:Cells, Cultured; D019662:Cucurbitaceae / Q000166:cytology / Q000254:growth & development*; D003470:Culture Media; D005638:Fruit; D006801:Humans; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000166:cytology / Q000254:growth & development; D018547:Plant Stems / Q000166:cytology / Q000254:growth & development; D014315:Triterpenes / Q000378:metabolism*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D003470:Culture Media; D010936:Plant Extracts; D014315:Triterpenes; C041246:cucurbitacin B