Synthesis and evaluation of three novel scyphostatin analogues as neutral sphingomyelinase inhibitors.
Pitsinos
Emmanuel N
EN
Organic and Bioorganic Chemistry Laboratory, NCSR Demokritos Institute of Physical Chemistry, P. O. Box 60228, 153 10 Ag. Paraskevi, Greece. pitsinos@chem.demokritos.gr
Wascholowski
Veit
V
Karaliota
Sevasti
S
Rigou
Chrisoula
C
Couladouros
Elias A
EA
Giannis
Athanassios
A
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors*
D000577:Amides; D004791:Enzyme Inhibitors; D011753:Pyrones; C121123:scyphostatin; D013108:Sphingomyelin Phosphodiesterase