[The advances in contractile modulation mechanism of the cardiomyocytes and the smooth muscle cells].
Heart and blood vessels are the pivotal organs that make up of the important system, cardiovascular system, of the body. They are associated functionally and both have the contractility. The pressure of the ventricles can elevate to a high level in a short time when heart contracts, so the cardiomyocytes should contract rapidly and powerfully. The contractile structure and the process of the calcium-modulation are required to meet the demand. The contractility of blood vessels is of slow and per durable characters which are compatible to the related function. This article describes the contractive structure and mechanism, and the related calcium-modulation mechanism cytologically, furthermore, introduces their differences and similarities, respectively.
Lü
Jun
J
Division of Cardiovascular Physiology and Pharmacology, Xi'an Jiaotong University, School of Medicine, Xi'an 710061.
Zang
Wei-Jin
WJ
Zhang
Chun-Hong
CH
D000818:Animals; D002118:Calcium / Q000378:metabolism; D015220:Calcium Channels / Q000378:metabolism; D003285:Contractile Proteins / Q000378:metabolism; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology*; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000502:physiology*; D009200:Myocardial Contraction / Q000502:physiology*; D032383:Myocytes, Cardiac / Q000502:physiology*; D032389:Myocytes, Smooth Muscle / Q000502:physiology; D019837:Ryanodine Receptor Calcium Release Channel / Q000378:metabolism; D019209:Troponin C / Q000378:metabolism
D015220:Calcium Channels; D003285:Contractile Proteins; D019837:Ryanodine Receptor Calcium Release Channel; D019209:Troponin C; D002118:Calcium