Bioinspired organic-inorganic composite materials prepared by an alternate soaking process as a tissue reconstitution matrix.
Poly(acrylic acid) (PAAc) grafted poly(ethylene) (PE) (PAAc-g-PE) film-apatite or calcium carbonate (CaCO3) composite materials were prepared by an alternate soaking process, which simply forms apatite or CaCO3 on the polymer materials by alternate soaking in Ca(2+)- and PO(3-)4- or CO(3)2- -containing solutions. X-ray diffraction analysis of the composite films indicated the presence of hydroxyapatite or CaCO3 on the film. Scanning electron microscopic observation revealed that the whole surface of the film was covered by the apatite or CaCO3. Cell compatibility tests of the apatite- or CaCO3-coated film suggested that the greater number of cells adhered on the films and that the cell proliferation properties were extremely greater on the films.
Ogomi
Daisuke
D
Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan.
Serizawa
Takeshi
T
Akashi
Mitsuru
M
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D002119:Calcium Carbonate / Q000737:chemistry*; D002448:Cell Adhesion; D002455:Cell Division; D002460:Cell Line; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D006882:Hydroxyapatites / Q000737:chemistry*; D008422:Materials Testing; D051379:Mice; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D006882:Hydroxyapatites; D002119:Calcium Carbonate