title: Geometrical stress-reducing factors in the anisotropic porcine heart valves.
abstract: This study carries out a detailed parameter study based on a nonlinear anisotropic finite-element model published previously. The aim of this study is to identify the stress-reducing influences from geometrical parameters such as stent height, valve diameter, and the nonuniform thickness of porcine aortic valves under static loading condition. The anisotropy of the valve is considered to be transversely isotropic with fibers oriented along the circumferential directions, which enables us to use a simple anisotropic constitutive model using uniaxial experimental data. The results showed that in general, higher stent height and smaller diameter combined with nonuniform thickness give rise to a much more reduced overall stress level. Although the absolute values of the peak stresses may be influenced by the detailed orientations of fibers, the trends of the stress variation with the geometrical factors seem to be qualitatively consistent within the parameter ranges considered.
authors: Department of Mechanical Engineering, University of Sheffield, Sheffield, S1 3JD, UK. X.Y.Luo@shef.ac.uk
authors: X Y
authors: XY
authors: Luo
authors: W G
authors: WG
authors: Li
authors: J
authors: J
authors: Li
mesh_terms: D000818:Animals; D016880:Anisotropy; D001021:Aortic Valve / Q000033:anatomy & histology* / Q000502:physiology* / Q000503:physiopathology / Q000601:surgery; D001705:Bioprosthesis; D003198:Computer Simulation; D019544:Equipment Failure Analysis / Q000379:methods*; D006350:Heart Valve Prosthesis; D008955:Models, Cardiovascular; D033081:Shear Strength; D013314:Stress, Mechanical; D013552:Swine