title: In vitro and in vivo study of lens refilling with poloxamer hydrogel.
abstract: OBJECTIVE
  To evaluate the compatibility of poloxamer hydrogel as a material for an injectable intraocular lens, in vivo and in vitro.
  
  
  METHODS
  The appropriate concentration of poloxamer hydrogel was determined for injection by examining the transparency and gelling temperature of this material, assessing the lens capsule refilling technique, and studying the postoperative findings in a rabbit model.
  
  
  RESULTS
  Poloxamer hydrogel showed excellent transparency and 25% was identified as an appropriate concentration for the lens refilling material. The authors developed a technique for injecting the material in vivo and obtained excellent short term results.
  
  
  CONCLUSIONS
  Poloxamer hydrogel was identified as an appropriate material for direct lens refilling, and the developed injection technique produced excellent short term results.
authors: Department of Ophthalmology, Seoul Municipal Boramae Hospital, Korea.
authors: Y K
authors: YK
authors: Han
authors: J W
authors: JW
authors: Kwon
authors: J S
authors: JS
authors: Kim
authors: C-S
authors: CS
authors: Cho
authors: W R
authors: WR
authors: Wee
authors: J H
authors: JH
authors: Lee
mesh_terms: D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D002387:Cataract Extraction; D020100:Hydrogels / Q000008:administration & dosage*; D007267:Injections; D007910:Lenses, Intraocular; D008297:Male; D020442:Poloxamer / Q000008:administration & dosage*; D011817:Rabbits
chemical_list: D020100:Hydrogels; D020442:Poloxamer