Total synthesis of the squalene synthase inhibitor zaragozic acid C by a carbonyl ylide cycloaddition strategy.
Nakamura
Seiichi
S
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Hirata
Yuuki
Y
Kurosaki
Takahiro
T
Anada
Masahiro
M
Kataoka
Osamu
O
Kitagaki
Shinji
S
Hashimoto
Shunichi
S
D001391:Azo Compounds / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis*; D003500:Cyclization; D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D015394:Molecular Structure; D013237:Stereoisomerism; D014233:Tricarboxylic Acids / Q000138:chemical synthesis
D001391:Azo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004791:Enzyme Inhibitors; D014233:Tricarboxylic Acids; C079090:zaragozic acid C; D013186:Farnesyl-Diphosphate Farnesyltransferase