title: The response of a bone resorption marker to marine recruit training.
abstract: OBJECTIVE
  This study measured the response of deoxypyridinoline, a biomarker of bone resorption, during 11 weeks of Marine recruit training.
  
  
  METHODS
  Urine samples were obtained from 155 female and 58 male Marine recruits from the first morning void every 3 days during training. Training miles of weight-bearing exercise were recorded daily, and injury data were obtained from the medical clinic staff.
  
  
  RESULTS
  Deoxypyridinoline was significantly (p < 0.001) increased at week 2 and weeks 9 through 11 for women and at weeks 10 and 11 for men. The increase in bone resorption corresponded to an increase in miles of weight-bearing exercise performed throughout training. The incidence of stress fracture and reaction was 3.9% and 14.8%, respectively, for women and 1.7% and 3.4%, respectively, for men.
  
  
  CONCLUSIONS
  Significant bone resorption took place at the end of Marine recruit training due to accumulation of weight-bearing exercise throughout training and the increase in marching toward the end.
authors: US Army Research Institute of Environmental Medicine, Military Performance Division, 42 Kansas Street, Natick, MA 01760, USA.
authors: Kathleen M
authors: KM
authors: Sheehan
authors: Michelle M
authors: MM
authors: Murphy
authors: Katy
authors: K
authors: Reynolds
authors: Joseph F
authors: JF
authors: Creedon
authors: Jeffrey
authors: J
authors: White
authors: Michael
authors: M
authors: Kazel
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000652:urine*; D015415:Biomarkers; D001862:Bone Resorption / Q000378:metabolism / Q000652:urine*; D003404:Creatinine / Q000652:urine; D015444:Exercise; D005260:Female; D015775:Fractures, Stress / Q000453:epidemiology / Q000209:etiology / Q000652:urine; D006801:Humans; D015994:Incidence; D008297:Male; D008889:Military Personnel; D012420:Running; D012727:Sex Characteristics; D014481:United States / Q000453:epidemiology
chemical_list: D000596:Amino Acids; D015415:Biomarkers; C036020:deoxypyridinoline; D003404:Creatinine