title: [Movement disorders in childhood: classification and genetic update].
abstract: Abnormal movements are not unusual in childhood. Recent genetic progresses provide a new approach of childhood movement disorders. Several loci have been identified in paroxysmal dyskinesia, or in Gilles de la Tourette syndrome. A gene has been cloned in Hallervorden-Spatz syndrome, and a gene has recently been implicated in benign hereditary chorea. Considerable advances concern the genetic of dystonic syndromes: several chromosomal localizations have been identified, and several genes have been cloned. Genetic advances allow nosographic reclassification of some entities and offer new molecular tools for a more appropriate diagnosis. The increasing wealth of genetic knowledge will provide further insight in the understanding of abnormal movement disorders in childhood.
authors: Service de neuropédiatrie, hôpital Saint-Eloi, 80, avenue Augustin-Fliche, 34295 cedex 5 Montpellier, France. a_roubertie@hotmail.com
authors: A
authors: A
authors: Roubertie
authors: F
authors: F
authors: Rivier
authors: S
authors: S
authors: Tuffery-Giraud
authors: V
authors: V
authors: Humbertclaude
authors: M
authors: M
authors: Claustres
authors: R
authors: R
authors: Cheminal
authors: B
authors: B
authors: Echenne
mesh_terms: D002648:Child; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D009069:Movement Disorders / Q000145:classification* / Q000235:genetics*