title: Internal carotid artery volume flow correlates to rCBF measurements.
abstract: BACKGROUND
  There is no simple, cost effective bedside method available for measuring global cerebral blood flow (CBF) rapidly and repeatedly.
  
  
  METHODS
  Based on the ultrasound technique a device was developed to measure flow volume per unit of time in the internal carotid artery. The system utilizes dual beam, angle-independent Doppler technology, and employs simultaneous sampling and full spectrum determination. The aim of this study was to evaluate this device in comparison with cerebral blood flow measurements using the well established Xenon(133) clearance technique.
  
  
  RESULTS
  10 patients suffering from SAH were included. 20 measurements were performed. CBF was measured employing the Xenon(133) clearance technique. Velocity profiles across the ICA were obtained with the high-resolution FlowGuard Doppler ultrasound flow system (Cardiosonix Ltd., Israel). According to the statistical analysis the ICA flow correlated significantly to the mean rCBF15 index of the hemisphere (p<0.0001).
  
  
  CONCLUSIONS
  This new device seems to be promising for monitoring cerebral blood flow in critically ill neurological and neurosurgical patients.
authors: Department of Neurosurgery, University of Regensburg, Regensburg, Germany. rolf.rothoerl@klinik.uni-regensburg.de
authors: R D
authors: RD
authors: Rothoerl
authors: K M
authors: KM
authors: Schebesch
authors: C
authors: C
authors: Woertgen
authors: A
authors: A
authors: Brawanski
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D001811:Blood Volume Determination / Q000295:instrumentation*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000503:physiopathology; D018616:Ultrasonography, Doppler, Duplex / Q000295:instrumentation*; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation*