title: Transmission of Staphylococcus aureus between healthy, lactating mothers and their infants by breastfeeding.
abstract: The authors have investigated Staphylococcus aureus transmission between healthy, lactating mothers without mastitis and their infants by breastfeeding using both bacteriological and molecular-epidemiological methods. They studied 8 healthy, lactating mothers without clinical signs of mastitis and their infants who were less than 3 months old. They collected samples of breast milk, swabs of the mothers' nipples, the infants' nares, and the infants' oral cavities. There was a 50% transmission rate between the pairs. As the result of 12 antibiotics' susceptibility, Methicillin-resistant S. aureus was isolated from 2 of the 4 pairs. Using pulsed-field gel electrophoresis, the authors determined chromosomal DNA restriction patterns of the S. aureus isolated from 4 mother-infant pairs. The DNA fragment patterns of the organism within a given mother-infant pair were indistinguishable or closely related. The results suggest that methicillin-resistant S. aureus or methicillin-sensitive S. aureus may be transmitted between healthy, lactating mothers without mastitis and their infants by breastfeeding.
authors: Department of Family Nursing, Graduate school of Health Sciences and Nursing Faculty of Medicine, University of Tokyo, Japan.
authors: Midori
authors: M
authors: Kawada
authors: Katsuko
authors: K
authors: Okuzumi
authors: Shigemi
authors: S
authors: Hitomi
authors: Chieko
authors: C
authors: Sugishita
mesh_terms: D000328:Adult; D001942:Breast Feeding / Q000009:adverse effects; D002353:Carrier State / Q000382:microbiology* / Q000635:transmission; D004269:DNA, Bacterial / Q000737:chemistry; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D016106:Methicillin Resistance; D008895:Milk, Human / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000635:transmission*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics
chemical_list: D004269:DNA, Bacterial