title: Treatment of bleeding in severe hemorrhagic pancreatitis with recombinant factor VIIa.
abstract: Recombinant factor VIIa (rFVIIa) has been used to treat bleeding complications in patients with hemophilia. It acts at the site of vessel injury, forming a complex with tissue factor to activate the clotting cascade. Recent reports have shown rFVIIa may be a useful hemostatic agent in patients after obstetrical, urologic, trauma, or transplant procedures. We report the first documented case of bleeding from hemorrhage pancreatitis treated with rFVIIa.
authors: Department of Surgery, Santa Barbara Cottage Hospital, Santa Barbara, California 93102, USA.
authors: Rob
authors: R
authors: Schuster
authors: Sarah J
authors: SJ
authors: Lee
authors: Donald
authors: D
authors: Rink
mesh_terms: D015942:Factor VIIa / Q000627:therapeutic use*; D006470:Hemorrhage / Q000150:complications / Q000628:therapy*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D006490:Hemostatics; D011994:Recombinant Proteins; D015942:Factor VIIa