title: On the existence of an optimum end-to-side junctional geometry in peripheral bypass surgery--a computer generated study.
abstract: BACKGROUND
  To investigate hemodynamic flow changes associated with vein cuffs and patches that may be responsible for improved patency of prosthetic infrainguinal grafts.
  
  
  METHODS
  The role of the graft-artery junction angle was examined by computational fluid dynamics to assess the influence of anastomotic geometry on wall shear stress (WSS) distributions. Three geometrically different junction configurations were studied and the WSS and WSS gradient (WSSG) values were compared.
  
  
  RESULTS
  The inclusion of a patch or a cuff moves the bed stagnation point (BSP) distally, increasing the area on the bed of the junction which experiences a BSP and reducing the strength of the recirculation region opposite the heel of the junction by 54.8 and 50.8%, respectively. The patched geometry promotes earlier recovery of the flow in the distal outflow segment (DOS) than for the unpatched model. Also, the helical flow patterns in the DOS associated with the cuffed geometry are stronger. The net effect of these changes are that peak WSSG values for the patched and cuffed geometries are three times lower than those for the uncuffed geometry.
  
  
  CONCLUSIONS
  This study provides some additional insights into the hemodynamics of graft-artery junction geometry which may influence future clinical practice.
authors: Department of Mechanical and Aeronautical Engineering, University of Limmerick, Ireland.
authors: M T
authors: MT
authors: Walsh
authors: E G
authors: EG
authors: Kavanagh
authors: T
authors: T
authors: O'Brien
authors: P A
authors: PA
authors: Grace
authors: T
authors: T
authors: McGloughlin
mesh_terms: D000714:Anastomosis, Surgical; D001158:Arteries / Q000503:physiopathology / Q000601:surgery; D001807:Blood Vessel Prosthesis; D003198:Computer Simulation; D018056:Hemorheology; D006801:Humans; D007264:Inguinal Canal / Q000098:blood supply*; D012039:Regional Blood Flow / Q000502:physiology*; D033081:Shear Strength; D014654:Vascular Patency / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology*