Radiation bronchitis in lung cancer patient treated with stereotactic radiation therapy.
We report a case of chronic radiation bronchitis that developed in a patient with lung cancer treated with fractionated stereotactic radiation therapy. A 73-year-old woman with a medically inoperable T1N0M0 adenocarcinoma of the lung was treated with stereotactic radiation therapy. By using eight non-coplanar ports, 50 Gy/5 fractions was delivered in two weeks. At four weeks, a partial response was obtained with no acute adverse reaction. She developed severe cough at six months. Fiberoptic bronchoscopy revealed thick circumferentially coated bronchial mucosa in close proximity to the tumor site. At 12 months, follow-up study confirmed marked stenotic change in the B6 segmental bronchus without tumor progression.
Uno
Takashi
T
Department of Radiology, Chiba University Graduate School of Medicine, Chiba City, Japan.
Aruga
Takashi
T
Isobe
Koichi
K
Motori
Ken
K
Kawakami
Hiroyuki
H
Ueno
Naoyuki
N
Ito
Hisao
H
D000230:Adenocarcinoma / Q000532:radiotherapy*; D000368:Aged; D029481:Bronchitis, Chronic / Q000175:diagnosis / Q000209:etiology*; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008279:Magnetic Resonance Imaging; D011832:Radiation Injuries / Q000175:diagnosis*; D020266:Radiotherapy, Conformal; D014057:Tomography, X-Ray Computed