[The excipient properties of shea butter compared with vaseline and lanolin].
A shea butter ointment containing 3% aureomycin (clortetracyclin hydrocloride) was prepared and some of its macroscopic and microscopic characteristics were evaluated. Then, the release of the active ingredient was compared by UV spectrophotometry with those obtained when excipients such as petroleum jelly and lanoline were used. Results had shown that the shea butter ointment had satisfactory characteristics. In the other hand, it was found that shea butter released the aureomycin easily and at a faster rate than the other excipients.
Thioune
Oumar
O
Laboratoire de Pharmacie Galénique et Législation, Faculté de Médecine, de Pharmacie et d'Odonto-stomatologie-UCAD, Dakar, Sénégal.
Khouma
Barham
B
Diarra
Mounibé
M
Diop
Alioune B
AB
Lô
Issa
I
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002751:Chlortetracycline / Q000008:administration & dosage; D005079:Excipients; D007809:Lanolin; D009823:Ointment Bases; D009824:Ointments; D009829:Oleic Acids; D010577:Petrolatum; D010938:Plant Oils; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D005079:Excipients; D009823:Ointment Bases; D009824:Ointments; D009829:Oleic Acids; D010938:Plant Oils; C434349:shea oleine; D007809:Lanolin; D010577:Petrolatum; D002751:Chlortetracycline