A case of renal cell carcinoma with bone and lymph node metastases.
We present a rare case of renal cell carcinoma (RCC) with a metastatic, mainly osteoblastic lesion of the skull and spread to the lymph nodes. Renal tumors are often associated with bone metastases; these are most often of the osteolytic type, while osteoblastic metastases are extremely rare. In the case presented here, the primary metastasis was a large osteoblastic lesion of the skull that spread to the lymph nodes. The patient has undergone treatment for 20 months with interleukin-2: 3 million IU/day (subcutaneous) for six consecutive days once every four weeks, ie a total weekly dose of 18 million IU.
Di Seri
Marisa
M
Department of Experimental Medicine and Pathology, Special Oncology Service, Policlinico Umberto I, University of Rome La Sapienza, Italy. marisadiseri@yahoo.com
Verì
Attilio
A
Colloca
Marialuisa
M
Spalletta
Bruno
B
Rossi
Rosalinda
R
Petrella
Pia Pierpaola
PP
Coletta
Deborah
D
Petricola
Fausto
F
Ricciardi
Serena
S
Frati
Luigi
L
D000970:Antineoplastic Agents / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000008:administration & dosage; D007680:Kidney Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged
D000970:Antineoplastic Agents; D007376:Interleukin-2