title: Photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to focal laser photocoagulation for radiation retinopathy.
abstract: A 50-year-old patient developed extrafoveal predominantly classic choroidal neovascularization in the right eye 2 months after undergoing focal laser photocoagulation for macular edema with hard exudates secondary to radiation retinopathy, with vision dropping from 20/20 to 20/100. The choroidal neovascularization responded to three verteporfin photodynamic therapy treatments with angiographic closure, which persisted for more than 15 months after the last treatment. At last follow-up 15 months after the third treatment, visual acuity improved by 8 lines to 20/20. Photodynamic therapy with verteporfin may be useful for treating patients with choroidal neovascularization secondary to argon laser photocoagulation.
authors: Lions Eye Institute, Albany Medical College, Albany, New York 12208, USA.
authors: Sophie J
authors: SJ
authors: Bakri
authors: Paul M
authors: PM
authors: Beer
mesh_terms: D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005451:Fluorescein Angiography; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects; D017075:Laser Coagulation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011166:Porphyrins / Q000627:therapeutic use*; D011832:Radiation Injuries / Q000209:etiology / Q000601:surgery*; D012160:Retina / Q000528:radiation effects; D012164:Retinal Diseases / Q000209:etiology / Q000601:surgery*; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D007457:Iodine Radioisotopes; D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin