PET practice in nuclear pharmacy.
PET systems, which are based on many years of work in theoretical and practical physics, provide a window into both normal and disease state biochemical processes not possible by other external imaging techniques. FDG is a workhorse of PET chemistry, helping to visualize the accumulation of glucose in cancer cells. A complex series of steps is involved in [18F]fluoride ion production to make a sterile, injectable solution of FDG. PET and CT scanners are being developed that increase greatly the clinical utility of both technologies.
Walker
Ronald C
RC
University of Arkansas for Medical Sciences, Little Rock, Ark., USA.
Zigler
Steven S
SS
D005462:Fluorine Radioisotopes / Q000737:chemistry / Q000302:isolation & purification; D019788:Fluorodeoxyglucose F18 / Q000138:chemical synthesis; D006801:Humans; D007553:Isotope Labeling / Q000379:methods; D009369:Neoplasms / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals / Q000138:chemical synthesis; D014055:Tomography, Emission-Computed / Q000295:instrumentation / Q000379:methods
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18