Changes in auditory cortex and the development of mismatch negativity between 2 and 6 months of age.
Evoked responses to stimulus deviance were compared in infants between 2 and 6 months of age. A deviant stimulus containing a short silent gap occasionally replaced a repeating standard stimulus matched in duration, intensity and approximate spectral content. At two months, the standard stimuli evoked only a positive slow wave, and its amplitude was increased in response to the deviant stimuli. By 6 months, the deviant stimuli evoked an increased negativity at approximately 200 ms, similar to the mismatch negativity (MMN) response in adults. The results are considered with respect to layer-specific cortical maturation during this period.
Trainor
Laurel
L
Department of Psychology, McMaster University, Hamilton, Canada ON L8S 4B2. ljt@mcmaster.ca
McFadden
Melissa
M
Hodgson
Lisa
L
Darragh
Lisa
L
Barlow
Jennifer
J
Matsos
Laura
L
Sonnadara
Ranil
R
D000161:Acoustic Stimulation; D000375:Aging / Q000502:physiology; D001303:Auditory Cortex / Q000254:growth & development* / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012016:Reference Values