title: The phosphotransferase system of Streptomyces coelicolor is biased for N-acetylglucosamine metabolism.
abstract: Mutation of the crr-ptsI gene locus revealed that Streptomyces coelicolor uses the phosphotransferase system (PTS) for N-acetylglucosamine uptake. crr, ptsI, and ptsH, which encode the three general PTS phosphotransferases, are induced by N-acetylglucosamine but not by other PTS substrates. Thus, the S. coelicolor PTS is biased for N-acetylglucosamine utilization, a novel feature that distinguishes this PTS from others.
authors: Lehrstuhl für Mikrobiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91058 Erlangen, Germany.
authors: Harald
authors: H
authors: Nothaft
authors: Dagmar
authors: D
authors: Dresel
authors: Andreas
authors: A
authors: Willimek
authors: Kerstin
authors: K
authors: Mahr
authors: Michael
authors: M
authors: Niederweis
authors: Fritz
authors: F
authors: Titgemeyer
mesh_terms: D000117:Acetylglucosamine / Q000378:metabolism*; D005798:Genes, Bacterial; D009154:Mutation; D010770:Phosphotransferases / Q000235:genetics / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism*; D013379:Substrate Specificity
chemical_list: D010770:Phosphotransferases; D000117:Acetylglucosamine