Role of calcium sensitivity modulation in skeletal muscle performance.
A common mechanism affecting Ca(2+) sensitivity in skeletal muscle is the proximity of myosin heads with actin filaments, a function of myofilament lattice spacing and myosin head mobility with respect to the myosin filament. This is an important mechanism of pCa(2+)(50) modulation by length, pH, regulatory light-chain phosphorylation, and temperature.
MacIntosh
Brian R
BR
Faculty of Kinesiology and Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 2N4, Canada.
D000818:Animals; D001831:Body Temperature / Q000502:physiology; D002118:Calcium / Q000378:metabolism*; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*
D002118:Calcium