Usefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy.
The prognostic role of the angiographic pattern of in-stent restenosis after gamma vascular brachytherapy was assessed from a pooled data set of 4 clinical trials comprising 295 irradiated patients with matched baseline and follow-up angiograms. The binary angiographic restenosis rate increased with worsening in-stent restenosis patterns; however, target lesion revascularization and major adverse cardiac event rates increased for focal, diffuse, and proliferative patterns of in-stent restenosis but not for total occlusions.
Costantini
Costantino O
CO
Cardiovascular Research Foundation, New York, New York 10021, USA.
Lansky
Alexandra J
AJ
Mintz
Gary S
GS
Shirai
Kazuyuki
K
Dangas
George
G
Mehran
Roxana
R
Stone
Gregg W
GW
Leon
Martin B
MB
D000368:Aged; D019917:Blood Vessel Prosthesis Implantation; D001918:Brachytherapy; D017023:Coronary Angiography; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays / Q000627:therapeutic use*; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging* / Q000209:etiology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012008:Recurrence; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome