Acute central and peripheral demyelination associated with Mycoplasma pneumoniae.
A 7-year-old female presented with Mycoplasma pneumoniae pneumonitis and a progressive ascending limb paralysis. She developed severe respiratory distress, requiring ventilation, and became apparently unresponsive with fixed dilated pupils. Peripheral nerves were inexcitable in nerve-conduction studies. Magnetic resonance imaging of the brain revealed evidence of extensive demyelination. Anti-GM1 immunoglobulin M antibody titers were raised. She improved after a second course of intravenous immunoglobulin and eventually made a full recovery.
Tan
Maw J
MJ
Sheffield Children's Hospital, Western Bank, UK.
Chattophadyay
Arup K
AK
Griffiths
Paul D
PD
Baxter
Peter S
PS
D001921:Brain / Q000382:microbiology / Q000473:pathology*; D002648:Child; D003711:Demyelinating Diseases / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006801:Humans; D009177:Mycoplasma pneumoniae; D010525:Peripheral Nerves / Q000382:microbiology / Q000473:pathology*; D011014:Pneumonia / Q000382:microbiology / Q000473:pathology*