title: Development and validation of a disease-specific treatment satisfaction questionnaire for gastro-oesophageal reflux disease.
abstract: BACKGROUND
  Currently, no disease-specific, patient-based, treatment satisfaction instruments related to gastro-oesophageal reflux disease exist.
  
  
  OBJECTIVE
  To develop and validate a treatment satisfaction questionnaire for gastro-oesophageal reflux disease (TSQ-G).
  
  
  METHODS
  A new questionnaire was developed from patient focus groups, clinician input and literature review. A validation study was conducted in treated gastro-oesophageal reflux disease patients. Ancillary measures included the Medical Outcomes Study Short Form-36, Quality of Life in Reflux and Dyspepsia, Gastrointestinal Symptom Rating Scale, Socially Desirable Response Scale, Patient Satisfaction Questionnaire-18 and physician and patient measures of symptoms and satisfaction. Statistical analyses included exploratory factor analysis, Cronbach's alpha, intra-class correlations, analyses of variance and t-tests.
  
  
  RESULTS
  A total of 198 gastro-oesophageal reflux disease patients participated in the study, with a mean age of 50.7 years, 68% female and 84% Caucasian. The physician-rated severity of gastro-oesophageal reflux disease was mild (32%), moderate (50%) and severe (18%); 83% were on proton pump inhibitors. The final TSQ-G consisted of 28 items with seven sub-scales; Cronbach's alpha ranged from 0.58 to 0.94. Correlations with the expected sub-scales of the ancillary measures were moderate to strong. The TSQ-G sub-scales discriminated significantly between levels of physician-rated disease severity, symptom days and patient and physician ratings of satisfaction.
  
  
  CONCLUSIONS
  The TSQ-G has excellent reliability and construct validity and appears to be a useful tool for the evaluation of treatment satisfaction in gastro-oesophageal reflux disease patients.
authors: MEDTAP International, Bethesda, MD 20814, USA. coyne@medtap.com
authors: K S
authors: KS
authors: Coyne
authors: I
authors: I
authors: Wiklund
authors: J
authors: J
authors: Schmier
authors: K
authors: K
authors: Halling
authors: A
authors: A
authors: Degl' Innocenti
authors: D
authors: D
authors: Revicki
mesh_terms: D005260:Female; D005764:Gastroesophageal Reflux / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires / Q000592:standards*; D016896:Treatment Outcome