Quality control of liquid herbal drug preparations: ethanol content and test on methanol and 2-propanol.
In the quality control of liquid herbal drug preparations, i.e. tinctures and liquid extracts, the ethanol content is determined and the test on methanol and 2-propanol is performed. Capillary headspace GC/MS methods for both analyses were developed and fully validated. These specific, selective, accurate and precise methods are a fast and fully automated alternative for the laborious methods of the European Pharmacopoeia, since they need no or only simple sample preparation.
Apers
Sandra
S
Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium. sandra.apers@ua.ac.be
Van Meenen
Els
E
Pieters
Luc
L
Vlietinck
Arnold
A
D019840:2-Propanol / Q000032:analysis* / Q000737:chemistry; D004353:Drug Evaluation, Preclinical / Q000379:methods; D000431:Ethanol / Q000032:analysis* / Q000737:chemistry; D000432:Methanol / Q000032:analysis* / Q000737:chemistry; D028321:Plant Preparations / Q000032:analysis* / Q000737:chemistry; D011786:Quality Control; D015203:Reproducibility of Results
D028321:Plant Preparations; D000431:Ethanol; D019840:2-Propanol; D000432:Methanol