New frontiers in bone tissue engineering.
No single scientific field can generate the ideal method of engineering bone. However, through collaboration and expansion of programs in bone tissue engineering, the right combination of materials, cells, growth factors, and methodology will come together for each clinical situation such that harvesting bone grafts will become obsolete. This article reviews the need for engineered bone and provides a historical perspective of bone engineering research, current research efforts, and the future direction of this work.
Calvert
Jay W
JW
University of California, Irvine, Aesthetic and Plastic Surgery Institute, 200 Manchester Avenue, Suite 650, Orange, CA 92868, USA. jcalvert@uci.edu
Weiss
Lee E
LE
Sundine
Michael J
MJ
D001672:Biocompatible Materials / Q000627:therapeutic use; D001861:Bone Regeneration / Q000502:physiology*; D016025:Bone Transplantation / Q000379:methods*; D001842:Bone and Bones / Q000502:physiology*; D006133:Growth Substances / Q000627:therapeutic use; D006801:Humans; D019651:Plastic Surgery Procedures / Q000379:methods; D033581:Stem Cell Transplantation / Q000379:methods; D013234:Stem Cells / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*
D001672:Biocompatible Materials; D006133:Growth Substances