title: Pain sensitivity in prematurely born adolescents.
abstract: BACKGROUND
  Several studies reported that preterm infants were found to be hypersensitive to pain. However, longitudinal and quantitative assessments of subsequent pain thresholds in adolescence are scarce.
  
  
  OBJECTIVE
  To assess the tenderness threshold in adolescents born prematurely compared with matched children born at full term.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Children in the community recruited from the files of the neonatal intensive care unit.
  
  
  METHODS
  Sixty adolescents (aged 12-18 years) born prematurely and 60 adolescents born at full term.
  
  
  METHODS
  Tenderness thresholds were assessed by tender-point count and by dolorimeter.
  
  
  RESULTS
  The preterm-born children had significantly more tender points (6.0 +/- 5.2 vs 3.3 +/- 3.3; P =.001) and lower tender thresholds (4.2 +/- 1.5 vs 4.8 +/- 1.6 kg; P =.04), measured by a dolorimeter, than children born at full term. In both groups, girls had significantly more tender points and lower tender thresholds. Despite their increased tenderness, most of the preterm children did not report pain or other related symptoms.
  
  
  CONCLUSIONS
  The fact that preterm-born children and adolescents display higher somatic pain sensitivity may be of relevance to physicians taking care of these children, since they may be prone to developing pain syndromes in the future. Further follow-up studies are needed to confirm this hypothesis.
authors: Department of Medicine, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev Beer Sheva, Israel. press@bgumail.bgu.ac.il
authors: Dan
authors: D
authors: Buskila
authors: Lily
authors: L
authors: Neumann
authors: Ehud
authors: E
authors: Zmora
authors: Marina
authors: M
authors: Feldman
authors: Arkady
authors: A
authors: Bolotin
authors: Joseph
authors: J
authors: Press
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002648:Child; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D010147:Pain Measurement; D017288:Pain Threshold; D011312:Pressure; D012720:Severity of Illness Index