Low-dose cyproterone acetate treatment of sexual acting out in men with dementia.
Increased sexual activity in patients with dementia is problematic for caregivers and has no proven treatment. This report describes two male patients who had dementia with pronounced sexual acting out. One patient had vascular dementia and the other patient had Parkinson's disease with associated dementia. After nonresponse to neuroleptics and sedatives, low-dose cyproterone acetate successfully reduced sexual acting out without relevant side effects in both patients.
Haussermann
Peter
P
Department of Neurology, TU Munich, Munich, Germany. peter.haeussermann@gmx.de
Goecker
David
D
Beier
Klaus
K
Schroeder
Stefan
S
D000184:Acting Out; D000368:Aged; D000726:Androgen Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D017373:Cyproterone Acetate / Q000008:administration & dosage* / Q000009:adverse effects; D003704:Dementia / Q000188:drug therapy* / Q000523:psychology; D015140:Dementia, Vascular / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005084:Exhibitionism / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D008297:Male; D008418:Masturbation / Q000188:drug therapy / Q000523:psychology; D010300:Parkinson Disease / Q000188:drug therapy* / Q000523:psychology; D012725:Sexual Behavior / Q000187:drug effects*
D000726:Androgen Antagonists; D017373:Cyproterone Acetate