A novel B*38 allele, B*3809, was identified via sequence -based typing of B-cell line no. 299 of the UCLA International Cell Exchange.
In this paper we report the identification of a new HLA-B allele in a sample that was distributed in the International UCLA Terasaki Cell/DNA Exchange, and the results were summarized in the final report of the 280th Cell Exchange. This novel allele officially designed B*3809 was found in B-cell line no. 299 from a Dutch Caucasoid donor and differs from B*3801 by mutation C-->G at position 483 in exon 3, resulting in an amino-acid substitution at codon 161 from aspartic acid in B*3801 to glutamic acid in B*3809, respectively.
Witter
K
K
Labor of Immunogenetics, University Munich, Munich, Germany. klaus.witter@kk-i.med.uni-muenchen.de
Lau
M
M
Schreuder
G M Th
GM
Albert
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ED
D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001483:Base Sequence; D002460:Cell Line; D005091:Exons; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D044465:White People
D015235:HLA-B Antigens