title: Interleukin-6 levels in hyperemesis gravidarum.
abstract: BACKGROUND
  Hyperemesis gravidarum (HG) is associated with higher levels of serum beta-hCG levels and hyperthyroidism. Interleukin-6 (IL-6), a pro-inflammatory cytokine, is reported to enhance secretion of beta-hCG from trophoblastic cell line.
  
  
  METHODS
  We measured serum levels of IL-6, thyroid hormones and beta-hCG of hyperemetic patients and gestational age-matched controls to search for a difference between the two groups.
  
  
  RESULTS
  There was a significant difference in beta-hCG ( p=0.028), though IL-6 levels were higher in the hyperemetic group, it did not reach a significant level. Interleukin-6 positively correlated with beta-hCG ( r=0.38 and p=0.13).
authors: Department of Obstetrics and Gynecology, School of Medicine, Celal Bayar University, 45020 Manisa, Turkey. kemal.kuscu@bayar.edu.tr
authors: Naci K
authors: NK
authors: Kuscu
authors: Yasemin
authors: Y
authors: Yildirim
authors: Faik
authors: F
authors: Koyuncu
authors: Ahmet
authors: A
authors: Var
authors: Bekir S
authors: BS
authors: Uyanik
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018709:Statistics, Nonparametric; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D006063:Chorionic Gonadotropin; D015850:Interleukin-6; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine