Asymmetric hydrogenation of ketones with polymer-supported chiral 1,2-diphenylethylenediamine.
[reaction: see text] A poly(ethylene glycol)-supported chiral diamine (PEG-2), in which the polymer is attached to the phenyl rings, has been synthesized and shown to be highly effective in asymmetric hydrogenation of unfunctionalized aromatic ketones with the possibility of reuse. PEG-2 can also serve as a chiral scaffold on which various immobilized chiral catalysts could be easily built.
Li
Xiaoguang
X
Leverhulme Centre for Innovative Catalysis, Department of Chemistry, University of Liverpool, UK.
Chen
Weiping
W
Hems
William
W
King
Frank
F
Xiao
Jianliang
J