A hexapeptide motif that electrostatically binds to the surface of titanium.
A hexapeptide motif, RKLPDA, that recognizes the surface of titanium was identified from a peptide phage selection. Mutational analyses showed electrostatic interaction was a major factor in the binding, paving a new way to modify the surface of Ti with active biomolecules.
Sano
Ken-Ichi
K
Department of Protein Engineering, Cancer Institute, Japanese Foundation for Cancer Research, Toshima, Tokyo 170-8455, Japan.
Shiba
Kiyotaka
K
D000595:Amino Acid Sequence; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry*; D019736:Prostheses and Implants; D011485:Protein Binding; D055672:Static Electricity; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
D009842:Oligopeptides; D014025:Titanium