Evolution of penicillin and erythromycin co-resistance in Streptococcus pneumoniae in Spain.
The temporal dynamics of penicillin and erythromycin co-resistance in Streptococcus pneumoniae based on two extensive multicentre Spanish surveillance SAUCE studies (1996-1997 and 1998-1999) is presented. Erythromycin resistance among penicillin non-susceptible isolates seems to have reached a limit as evidenced by a null increase between the two surveys, whereas it is growing among penicillin-susceptible pneumococci.
García-Rey
C
C
Medical Department, GlaxoSmithKline, Madrid, Spain.
Bouza
E
E
Aguilar
L
L
García-de-Lomas
J
J
Baquero
F
F
D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D004917:Erythromycin / Q000494:pharmacology*; D019143:Evolution, Molecular; D006801:Humans; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D011159:Population Surveillance; D013030:Spain; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification
D010406:Penicillins; D004917:Erythromycin