Transverse dephasing optimized solid-state NMR spectroscopy.
It is shown how coherence lifetimes in solid-state NMR experiments can be controlled. New decoupling schemes are introduced which actively optimize dephasing times, providing increases of up to a factor of 2 with respect to the best existing schemes. The new schemes are implemented in transverse-dephasing-optimized (TDOP) NMR experiments for the disorded solid cellulose, and for a microcrystalline protein, where sensitivity improvements of up to a factor of 5 are obtained.
De Paëpe
G
G
Laboratoire de Chimie, UMR 5182 CNRS/ENS, Laboratoire de Recherche Conventionné du CEA (no. 23V), Ecole Normale Supérieure de Lyon, 69364 Lyon, France.
Giraud
N
N
Lesage
A
A
Hodgkinson
P
P
Böckmann
A
A
Emsley
L
L
D001412:Bacillus subtilis / Q000737:chemistry; D001426:Bacterial Proteins / Q000737:chemistry; D002250:Carbon Radioisotopes; D002482:Cellulose / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D010750:Phosphoproteins / Q000737:chemistry*
D001426:Bacterial Proteins; D002250:Carbon Radioisotopes; C118042:Crh protein, Bacillus subtilis; D010750:Phosphoproteins; D002482:Cellulose