title: Cytotoxic activity of Ozoroa insignis from Zimbabwe.
abstract: The crude methanol bark extract of the Zimbabwean medicinal plant, Ozoroa insignis, showed in-vitro cytotoxic activity against Hep-G2 (human hepatocellular carcinoma), MDA-MB-231 (human mammary adenocarcinoma), and 5637 (human primary bladder carcinoma). Bioactivity-directed chromatographic separation led to isolation of anacardic acid and ginkgoic acid as the cytotoxic components.
authors: Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA.
authors: Angela I
authors: AI
authors: Rea
authors: Jennifer M
authors: JM
authors: Schmidt
authors: William N
authors: WN
authors: Setzer
authors: Samson
authors: S
authors: Sibanda
authors: Catherine
authors: C
authors: Taylor
authors: Ephraim T
authors: ET
authors: Gwebu
mesh_terms: D027926:Anacardiaceae; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D016488:Medicine, African Traditional; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D015030:Zimbabwe
chemical_list: D000970:Antineoplastic Agents; D010936:Plant Extracts