[Studies on the effects of human chorionic gonadotropin on the growth of human gastric adenocarcinoma cells].
OBJECTIVE
To investigate the effects of human gastric chorionic gonadotropin (hCG) on the growth of human gastric adenocarcinoma cells.


METHODS
MTT reduction assay was used to determine the cell growth and survival rates.


RESULTS
Within the concentration range of 10(-11)-10(-6) mol/L, hCG could slightly stimulate the growth of gastric cancer cells but in a obvious time-dependent manner.


CONCLUSIONS
hCG has slightly stimulatory effect on the proliferation gastric adenocarcinoma cells, suggestion that hCG may possibly play a role in regulation the tumorigenesis of gastric cancer.
Zhang
Qunzhou
Q
Department of Biochemistry & Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Liao
Ying
Y
Li
Ronghui
R
Chen
Manling
M
D000230:Adenocarcinoma / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D006801:Humans; D013274:Stomach Neoplasms / Q000473:pathology*; D014407:Tumor Cells, Cultured
D006063:Chorionic Gonadotropin