Human immunodeficiency virus-associated hemophagocytosis with iron-deficiency anemia and massive splenomegaly.
We present a case of hemophagocytic syndrome in a human immunodeficiency virus-positive man with iron-deficiency anemia that did not respond to highly active antiretroviral therapy. Clinical resolution occurred only after a splenectomy was performed.
Sproat
Lisa O
LO
Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
Pantanowitz
Liron
L
Lu
Chuanyi M
CM
Dezube
Bruce J
BJ
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000150:complications*; D019380:Anti-HIV Agents / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D005260:Female; D006678:HIV; D015658:HIV Infections / Q000150:complications*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D013156:Splenectomy; D013163:Splenomegaly / Q000209:etiology* / Q000601:surgery
D019380:Anti-HIV Agents