title: Choledochoenterostomy with an anti-reflux mechanism.
abstract: A new technique of choledochoenterostomy was devised to solve some of the problems of enterobiliary anastomosis with a normal calibre. The distal extremity of the common bile duct is completely surrounded by the bowel mucosa to a length of 3 cm after seromyectomy of a bowel wall rectangle of 4 x 1 cm. Experimental studies in rats and dogs demonstrated that this procedure prevents the risks of anastomotic disruption and functions like a mechanical unidirectional valve, which has great efficacy in stopping enterobiliary reflux. Studies in ten patients with obstructive jaundice with an extrahepatic biliary dilation less than 1.2 cm diameter submitted to this procedure confirmed the experimental results. All patients were asymptomatic, without jaundice and with normalization of the liver enzymes after 2 months. The permeability of the valvular anastomosis studied by cholangiography, the HIDA 99mTc test and manometry was quite similar to other classical biliary-enteric anastomosis. In contrast, anti-reflux efficacy was only demonstrated in patients with a valvular anastomosis.
authors: Lisbon Faculty of Medicine, Lisbon, Portugal.
authors: F
authors: F
authors: Veiga Fernandes
authors: J
authors: J
authors: Coutinho
authors: M P
authors: MP
authors: Henriques
authors: B
authors: B
authors: da Silva
authors: A
authors: A
authors: Baptista
authors: A I
authors: AI
authors: Santos
authors: F
authors: F
authors: Godinho
mesh_terms: D000818:Animals; D001652:Bile Ducts / Q000378:metabolism; D002768:Choledochostomy / Q000379:methods*; D002908:Chronic Disease; D004195:Disease Models, Animal; D004285:Dogs; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000150:complications; D010195:Pancreatitis / Q000150:complications; D051381:Rats