Iridium-mediated asymmetric hydrogenation of 2,3-diphenylbutadiene: a revealing kinetic study.
Hydrogenation of 2,3-diphenylbutadiene mediated by a chiral iridium carbene oxazoline complex was studied. The kinetics of the reaction showed that it occurred in two distinct stages. The first corresponded to slow consumption of the diene to form half-hydrogenated products, i.e., monoenes. After all the diene was consumed, however, the reaction was much faster and more stereoselective. These data were interpreted in terms of possible catalytic intermediates.
Cui
Xiuhua
X
Department of Chemistry, Texas A & M University, Box 30012, College Station, TX 77842-3012, USA.
Burgess
Kevin
K