title: Concentration-independent spontaneously forming biomimetric vesicles.
abstract: In this Letter we present small-angle neutron scattering data from a biomimetic system composed of the phospholipids dimyristoyl and dihexanoyl phosphorylcholine (DMPC and DHPC, respectively). Doping DMPC-DHPC multilamellar vesicles with either the negatively charged lipid dimyristoyl phosphorylglycerol (DMPG, net charge -1) or the divalent cation, calcium (Ca2+), leads to the spontaneous formation of energetically stabilized monodisperse unilamellar vesicles whose radii are concentration independent and in contrast with previous experimental observations.
authors: National Research Council, Steacie Institute for Molecular Sciences, Chalk River, Ontario, K0J 1J0, Canada.
authors: M-P
authors: MP
authors: Nieh
authors: T A
authors: TA
authors: Harroun
authors: V A
authors: VA
authors: Raghunathan
authors: C J
authors: CJ
authors: Glinka
authors: J
authors: J
authors: Katsaras
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D002118:Calcium / Q000737:chemistry; D002413:Cations, Divalent; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry*; D007700:Kinetics; D008081:Liposomes / Q000737:chemistry*; D010742:Phospholipid Ethers / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: C052298:1,2-dihexadecyl-sn-glycero-3-phosphocholine; D002413:Cations, Divalent; D008081:Liposomes; D010742:Phospholipid Ethers; D002118:Calcium; D004134:Dimyristoylphosphatidylcholine