title: [Relationship between macrophage migration inhibitory factor and cardiac function in patients with congestive heart failure].
abstract: OBJECTIVE
  To examine the level of plasma macrophage migration inhibitory factor (MIF) in patients with congestive heart failure (CHF) and its relationship with cardiac function.
  
  
  METHODS
  The levels of MIF were measured in 278 CHF patients and 85 normal subjects using enzyme-linked immuno-sorbent assay (ELISA).
  
  
  RESULTS
  Elevated MIF levels were detected in the patients with heart failure, and the elevation was more significant in cases of coronary artery disease in comparison with that identified in cases of dilated cardiomyopathy.
  
  
  CONCLUSIONS
  The overactivation of MIF may be involved in the pathogenesis of heart failure.
authors: Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangzhou 510080, China.
authors: Yuan
authors: Y
authors: Liu
authors: Xi-yong
authors: XY
authors: Yu
authors: Qiu-xiong
authors: QX
authors: Lin
authors: Min
authors: M
authors: Yang
authors: Zhi-xin
authors: ZX
authors: Shan
authors: Meng
authors: M
authors: Zheng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002311:Cardiomyopathy, Dilated / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D008263:Macrophage Migration-Inhibitory Factors / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D008263:Macrophage Migration-Inhibitory Factors