Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, Botswana.
To exclude tuberculosis, WHO/UNAIDS recommends considering medical history, symptom screen, and chest radiograph before starting tuberculosis prevention in people infected with HIV. The value of a chest radiograph for this purpose is unknown. We prospectively assessed 935 HIV-infected outpatients seeking isoniazid preventive therapy. Of 935 patients, 692 (74%) had no signs or symptoms of tuberculosis. Of these 692, 123 (18%) were lost during the chest radiograph process, and one (0.2%) of the remaining 563 was diagnosed with tuberculosis on the basis of the chest radiograph. A screening chest radiograph should not be required routinely for asymptomatic people taking isoniazid as preventive treatment in settings able to screen for signs and symptoms of tuberculosis.
Mosimaneotsile
B
B
BOTUSA Project, US Centers for Disease Control and Prevention, Gaborone, Botswana. baru1@cdc.gov
Talbot
E A
EA
Moeti
T L
TL
Hone
N M
NM
Moalosi
G
G
Moffat
H J
HJ
Lee
E J
EJ
Kenyon
T A
TA
D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001902:Botswana / Q000453:epidemiology; D015897:Comorbidity; D005069:Evaluation Studies as Topic; D005260:Female; D015658:HIV Infections / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008400:Mass Chest X-Ray / Q000706:statistics & numerical data; D008875:Middle Aged; D010865:Pilot Projects; D011314:Preventive Health Services; D011446:Prospective Studies; D013902:Radiography, Thoracic / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000517:prevention & control*
D000995:Antitubercular Agents; D007538:Isoniazid