title: Efficacy of embolization in traumatic uterine vascular malformations.
abstract: OBJECTIVE
  To evaluate the efficacy of embolotherapy in patients with bleeding traumatic uterine arteriovenous malformations (AVMs).
  
  
  METHODS
  A retrospective review of all patients who underwent pelvic arterial embolization at our institution between July 1992 and September 2002 was performed. Fifteen patients were diagnosed with a uterine vascular malformation on duplex ultrasonography and correlative MR imaging. Serial beta-human chorionic gonadotropin levels were measured to exclude gestational trophoblastic neoplasia. All patients underwent transcatheter embolization of the uterine arteries. Embolizations were performed with use of standard 4-5-F catheters and microcatheters when necessary. Embolic agents in the 25 procedures included glue only (n = 13), polyvinyl alcohol (PVA) particles and glue (n = 4), PVA particles (n = 2), Gelfoam (n = 2), coils (n = 1), PVA particles and coils (n = 1), glue and Gelfoam (n = 1), and glue and coils (n = 1). PVA particle size ranged from 350 to 1,000 micro m. Outcomes assessed were cessation of bleeding, persistence or resolution of the AVM, complications, and pregnancy after embolization. These were assessed by chart, laboratory, and imaging reviews.
  
  
  RESULTS
  A total of 25 embolization procedures were performed in 15 patients. Six patients required repeat embolization (one patient underwent embolization on six occasions; five patients had two embolization procedures each) for recurrence of bleeding. Sixteen procedures were performed on an elective basis and nine were performed on an emergent basis. The technical success rate of embolization was 100%. The clinical success rate was 93%: bleeding was controlled in 14 of 15 patients and one patient underwent a hysterectomy. Four of the 15 patients subsequently had a total of five uneventful intrauterine pregnancies carried to term. The 14 patients who underwent successful embolization had no recurrence of bleeding at a median follow-up of 53 months (range, 3-124 months) after treatment. Three patients were eventually lost to follow-up. One minor complication (0.4%) of non-flow-limiting dissection of the internal iliac artery occurred.
  
  
  CONCLUSIONS
  Percutaneous embolotherapy is a safe and effective treatment for traumatic AVMs. This procedure allows for preservation of uterine function with the possibility of future pregnancy and should be considered as a primary treatment option.
authors: Division of Vascular and Interventional Radiology, Toronto Western Hospital, University Health Network-University of Toronto, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada.
authors: Sangeet
authors: S
authors: Ghai
authors: Dheeraj K
authors: DK
authors: Rajan
authors: Murray R
authors: MR
authors: Asch
authors: Derek
authors: D
authors: Muradali
authors: Martin E
authors: ME
authors: Simons
authors: Karel G
authors: KG
authors: TerBrugge
mesh_terms: D000328:Adult; D001164:Arteriovenous Fistula / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006801:Humans; D011142:Polyvinyl Alcohol / Q000627:therapeutic use; D011247:Pregnancy; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D014599:Uterus / Q000098:blood supply*
chemical_list: D011142:Polyvinyl Alcohol