Hsp40 is involved in cilia regeneration in sea urchin embryos.
In a previous paper we demonstrated that, in Paracentrotus lividus embryos, deciliation represents a specific kind of stress that induces an increase in the levels of an acidic protein of about 40 kD (p40). Here we report that deciliation also induces an increase in Hsp40 chaperone levels and enhancement of its ectodermal localization. We suggest that Hsp40 might play a chaperoning role in cilia regeneration.
Casano
Caterina
C
Dipartimento di Biologia Cellulare e dello Sviluppo Alberto Monroy, Palermo, Italy. cascate@unipa.it
Gianguzza
Fabrizio
F
Roccheri
Maria C
MC
Di Giorgi
Rossana
R
Maenza
Luigia
L
Ragusa
Maria A
MA
D000818:Animals; D018385:Centrosome / Q000378:metabolism; D002923:Cilia / Q000378:metabolism* / Q000502:physiology / Q000648:ultrastructure; D046508:Culture Techniques; D004475:Ectoderm / Q000378:metabolism; D015180:Electrophoresis, Gel, Two-Dimensional; D004625:Embryo, Nonmammalian / Q000378:metabolism; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000096:biosynthesis*; D018832:Molecular Chaperones / Q000096:biosynthesis*; D012038:Regeneration; D012617:Sea Urchins; D013312:Stress, Physiological / Q000378:metabolism*
D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones