title: [Malignant renal tumors before one year of age. Experience of a North African pediatric surgery service].
abstract: The malignant tumours of the kidney are not very frequent during the first year of life and pose diagnostic and therapeutic problems. The aim of this work is to make an analysis of the epidemiologic, clinical and anatomo-pathological characteristics of these tumours during the first year of life and a development on the therapeutic methods and their results.
  
  
  METHODS
  [corrected] This is a retrospective study of 8 observations of malignant tumours of the kidney whose first symptomatology appeared during the first year of life.
  
  
  RESULTS
  The malignant tumours of the kidney observed before the one year age constituted 18% of the tumours of the kidney in the child. A female prevalence was noted with a sex-ratio of 0.6. The assessment of extension found cutaneous (one case), ganglionic (one case) and pulmonary (two cases) metastases. First chemotherapy was prescribed to five patients. The surgery consisted on a widened nephrectomy in seven cases and a tumorectomy for an infant presenting a nephroblastomatosis. The tumour corresponded to a nephroblastoma in seven cases and a rhabdoide tumour in the last case. Mortality was high (50%) caused by the toxicity of chemotherapy in three cases and an advanced stage of cancer in one case.
  
  
  CONCLUSIONS
  Renal tumoral pathology occurring in infants less than one year of age poses true etiologic and therapeutic problems. The high frequency of the nephroblastoma and the absence of benign tumour in our series encourage us to evocate more often the malignant renal tumours and to practice per cutaneous biopsies in case of diagnostic doubt.
authors: Service de chirurgie pédiatrique, centre hospitalier universitaire Fattouma-Bourguiba, 5000 Monastir, Tunisie. mongi.mekki@fmm.rnu.tn
authors: M
authors: M
authors: Mekki
authors: A
authors: A
authors: Landolsi
authors: M
authors: M
authors: Belghith
authors: I
authors: I
authors: Krichene
authors: S
authors: S
authors: Chelly
authors: A
authors: A
authors: Zakhama
authors: R
authors: R
authors: Jouini
authors: M
authors: M
authors: Golli
authors: M
authors: M
authors: Gahbiche
authors: A
authors: A
authors: Nouri
mesh_terms: D000352:Africa, Northern; D000367:Age Factors; D044383:Black People; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male; D012189:Retrospective Studies