title: [Sphingolipid and apoptosis].
abstract: Over the last decade, considerable progress has been made in the study of sphingolipids with the development of biological techniques. Sphingolipids play important roles in diverse physiological process, including cytoskeleton migration, angiogenesis, embryonic development and signal transduction. Except for this, the lastest evidence has suggested that sphingolipids and their metabolite (ceramide, sphingosine, sphingosine 1-phosphate) can induce apoptosis in a wide variety of tumor cell lines such as LoVo HT29, Bel7402, A549, CNE2 cells. This paper is attempted to review the recent advances of investigation into the relationship between sphingolipids and apoptosis.
authors: College of Food Science, China Agricultural University, Beijing 100094.
authors: Jing
authors: J
authors: Wang
authors: Xiao-Song
authors: XS
authors: Hu
authors: Jie-Ping
authors: JP
authors: Shi
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002465:Cell Movement; D002518:Ceramides / Q000502:physiology; D003599:Cytoskeleton / Q000502:physiology; D006801:Humans; D008246:Lysophospholipids / Q000502:physiology; D018919:Neovascularization, Physiologic; D013107:Sphingolipids / Q000378:metabolism / Q000502:physiology*; D013110:Sphingosine / Q000031:analogs & derivatives / Q000502:physiology
chemical_list: D002518:Ceramides; D008246:Lysophospholipids; D013107:Sphingolipids; C060506:sphingosine 1-phosphate; D013110:Sphingosine