title: Comparison of perioperative blood salvage and postoperative reinfusion of drained blood during surgical correction of craniosynostosis in infants.
abstract: BACKGROUND
  The surgical correction of craniosynostosis may be associated with extensive blood loss and transfusion. The aim of this study was to compare the efficacy of the perioperative use of the continuous autotransfusion system (CATS group) and of the postoperative use of the CBCII ConstaVac(R) system (CV group) to reduce homologous transfusion in infants during repair of craniosynostosis.
  
  
  METHODS
  Two groups of consecutive infants, weighing <10 kg, and scheduled for the surgical correction of craniosynostosis, were compared retrospectively according to the blood salvaging system used: CATS group and CV group. The primary endpoint was the comparison of the total volume of homologous blood transfused.
  
  
  RESULTS
  There was no significant difference between the CV (n = 69) and the CATS (n = 135) groups with regard to physical, preoperative and postoperative data, except for the type of craniosysnostosis with more scaphocephaly in the CV group (P = 0.03). No significant difference in blood loss and homologous transfusion was observed between the two groups during the perioperative period. Two subgroups of patients were also compared: a subgroup including patients operated on with a linear craniectomy for scaphocephaly, and a subgroup including all other patients. There was also no significant difference in blood loss and homologous transfusion between the CV and the CATS groups for these two subgroups of patients.
  
  
  CONCLUSIONS
  Our results suggest that the postoperative use of the CBCII ConstaVac(R) system is as efficient as the perioperative use of the CATS(R) system for reducing homologous blood transfusion during repair of craniosynostosis in infants weighing <10 kg.
authors: Département d'Anesthésie-Réanimation Service de Neurochirurgie Pédiatrique, CHU Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Cedex, France. gilles.orliaguet@nck.ap-hop-paris.fr
authors: Gilles A
authors: GA
authors: Orliaguet
authors: Marie
authors: M
authors: Bruyere
authors: Philippe G
authors: PG
authors: Meyer
authors: Stéphane
authors: S
authors: Blanot
authors: Dominique
authors: D
authors: Renier
authors: Pierre A
authors: PA
authors: Carli
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control* / Q000706:statistics & numerical data; D001804:Blood Transfusion, Autologous / Q000295:instrumentation / Q000379:methods*; D003398:Craniosynostoses / Q000601:surgery*; D005260:Female; D006400:Hematocrit; D006801:Humans; D007223:Infant; D008297:Male; D019990:Perioperative Care / Q000295:instrumentation / Q000379:methods*; D011182:Postoperative Care / Q000379:methods*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric