title: Orthotopic liver transplantation in treatment of 77 patients with end-stage hepatic disease.
abstract: OBJECTIVE
  To summarize the experience of human orthotopic liver transplantation (OLTx) in treatment of patients with end-stage hepatic disease and their perioperative management.
  
  
  METHODS
  A retrospective analysis was made on OLTx performed in 77 patients from April 1993 to September 2001 in our department included combined liver-kidney transplantation (6 patients) and living related liver transplantation (2). Among them, 76 were adults and 1 was infant (67 males and 10 females). The donors included 75 non-heart beating donors and 2 living related donors. Veno-venous bypass was used only in 45 cases during the operation. immunosuppressive agents consisted of cyclosporine, cellcept, ALG corticosteroids and FK506.
  
  
  RESULTS
  The one-year survival rates of grafts and recipients with benign hepatic disease were 75%. The recipients this year are surviving with good function of grafts.
  
  
  CONCLUSIONS
  Liver transplantation is the best therapeutic method for a large number of patients with end-stage hepatic disease in China.
authors: Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. linzhou8@mail.hz.zj.cn
authors: Shu-Shen
authors: SS
authors: Zheng
authors: Dong-Sheng
authors: DS
authors: Huang
authors: Wei-Lin
authors: WL
authors: Wang
authors: Ting-Bo
authors: TB
authors: Liang
authors: Min
authors: M
authors: Zhang
authors: Yan
authors: Y
authors: Shen
authors: Xiao
authors: X
authors: Xu
authors: Jian
authors: J
authors: Wu
authors: Sheng
authors: S
authors: Yan
authors: Hua
authors: H
authors: Guo
authors: An-Wei
authors: AW
authors: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018281:Cholangiocarcinoma / Q000401:mortality / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D017093:Liver Failure / Q000401:mortality* / Q000601:surgery*; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery; D016031:Liver Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies