Seasonal and phenological variations of the essential oil from the narrow endemic species Artemisia molinieri and its biological activities.
The volatile components of the aerial parts of Artemisia molinieri, an endemic wormwood of southern France, were analyzed by GC and GC-MS. Among the 69 compounds identified, major components were ascaridole (19-76%), alpha-terpinene (traces-36%), p-cymene (1-17%), 1,8-cineole (0.3-8%), and germacrene D (0.6-15%). Quantitative variations have been characterized following the season, the phenological cycle, and the aging of the plants. Bioassays have been performed on a sample of essential oil, which has shown a strong inhibition of the growth of both tested yeasts (Candida albicans and Saccharomyces cerevisiae var. chevalieri) and minor activity on both tested Gram-negative bacteria (Escherichia coli and Enterococcus hirae). The oils have shown interesting antioxidant activities on the basis of alpha-tocopherol as reference compound, up to 400-1200%.
Masotti
Véronique
V
Laboratoire Dynamique et Ressources du Végétal, E.A. 2202-Biodiversité, Université de Provence, UFR DENTES et SVTE, case 17, 3 place Victor Hugo, F-13331 Marseille Cedex 3, France. vmasotti@up.univ-mrs.fr
Juteau
Fabien
F
Bessière
Jean Marie
JM
Viano
Josette
J
D000975:Antioxidants / Q000032:analysis; D019306:Artemisia / Q000737:chemistry*; D002176:Candida albicans / Q000187:drug effects; D002849:Chromatography, Gas; D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols / Q000032:analysis; D000081007:Cymenes; D004926:Escherichia coli / Q000187:drug effects; D000077591:Eucalyptol; D008401:Gas Chromatography-Mass Spectrometry; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry*; D010545:Peroxides / Q000032:analysis; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology; D012621:Seasons; D013211:Staphylococcus aureus / Q000187:drug effects
D000975:Antioxidants; D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010545:Peroxides; D010938:Plant Oils; C043372:ascaridole; C007210:4-cymene; C018669:gamma-terpinene; D000077591:Eucalyptol