Cervical myelopathy due to chronic vitamin B12 deficiency or herniated cervical disc or both.
OBJECTIVE
A female patient with diagnosis of combined system degeneration due to vitamin B12 deficiency and multi-level cervical disc herniation underwent a comprehensive neurophysiologic tests.


METHODS
Central conduction time (CCT) was calculated after recording of the SSEPs from cervical, brainstem, and parietal sensory cortex to peripheral stimulation.


RESULTS
The CCT between the lower cervical spine and brainstem was 3.63 msec and 3.41 msec for left and right side. All values were within the normal range. The visual EPs and brain-stem auditory EPs were also normal. The MR imaging of the cervical region was remarkable for multi-level degenerative changes as well as osteophyte formation at C4-7 segments causing canal stenosis.


CONCLUSIONS
It is possible that her symptoms are related to two separate chronic problems. The first is history of B12 deficiency, causing a subacute systems degeneration syndrome. The second is evidence of a cervical spondylotic myelopathy.
Haghighi
S S
SS
Clinical Neurodiagnostic Department, Sharp Memorial Hospital, 7901 Frost Street, San Diego, California 92123, USA. Siavash.haghighi@sharp.com
Zhang
R
R
Stein
D
D
D002574:Cervical Vertebrae; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology