Cross-reactivity between erythropoietin and thrombopoietin at the level of Mpl does not account for the thrombocytosis seen in iron deficiency.
Geddis
Amy E
AE
Kaushansky
Kenneth
K
D018798:Anemia, Iron-Deficiency / Q000150:complications*; D003429:Cross Reactions; D004921:Erythropoietin / Q000737:chemistry / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D009363:Neoplasm Proteins / Q000276:immunology*; D011518:Proto-Oncogene Proteins / Q000276:immunology*; D018121:Receptors, Cytokine / Q000276:immunology*; D053628:Receptors, Thrombopoietin; D017386:Sequence Homology, Amino Acid; D013922:Thrombocytosis / Q000209:etiology*; D013926:Thrombopoietin / Q000737:chemistry / Q000276:immunology*
D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D018121:Receptors, Cytokine; D053628:Receptors, Thrombopoietin; D004921:Erythropoietin; C082218:MPL protein, human; D013926:Thrombopoietin