[Cure of adult acute myeloblastic leukemia].
Despite major recent advances in the understanding of the molecular biology of adult acute myeloblastic leukemia(AML), the treatment of the disease remains challenging. This review summarizes literature in the field of curative chemotherapy for adult acute myeloblastic leukemia(AML). In particular, detailed analysis of curing leukemia in patients treated with risk-oriented chemotherapy and in patients with APL was presented. In addition, results using our curative chemotherapy approach for adult AML were reported. Lastly, future directions for curing adult AML were discussed.
Uzuka
Yoshiro
Y
Sendai Blood Disease Center.
Saito
Yoshiko
Y
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D002869:Chromosome Aberrations; D002986:Clinical Trials as Topic; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000628:therapy*; D011379:Prognosis; D012306:Risk; D014212:Tretinoin / Q000008:administration & dosage
D014212:Tretinoin