Metastatic melanoma of the pituitary gland. Case report.
The authors report on the clinical features and imaging studies in a case of metastatic melanoma of the pituitary gland. Cerebral metastatic melanoma and pituitary metastasis from any source are commonly associated with systemic metastasis, whereas pituitary metastatic melanoma without widespread disease dissemination is distinctly rare. This 46-year-old man presented with diabetes insipidus and anterior pituitary dysfunction 5 years after he underwent resection of a cutaneous malignant melanoma of the neck. Magnetic resonance imaging demonstrated the presence of melanin within a sellar tumor mass. Transsphenoidal resection was performed and histopathological examination of tumor material confirmed metastatic melanoma. Postoperative [18F]fluorodeoxyglucose-positron emission tomography revealed no other focus of hypermetabolism in the patient's body.
Leung
Gilberto Ka Kit
GK
Division of Neurosurgery, Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, Peoples Republic of China. gilbertleung2002@yahoo.com
Chow
Wing Sun
WS
Tan
Kathryn Choon Beng
KC
Fan
Yiu Wah
YW
Lam
Karen Siu Ling
KS
D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery