Lacquer crack formation after photodynamic therapy.
OBJECTIVE
To report the occurrence of a lacquer crack after photodynamic therapy (PDT) of choroidal neovascularization (CNV) in a patient with pathologic myopia.


METHODS
PDT was performed with verteporfin, which was activated by a diode laser light at 690 nm.


RESULTS
The left eye of a 42-year-old woman was treated with PDT because of juxtafoveal CNV caused by pathologic myopia. No lacquer crack was present in the macula on either fluorescein or indocyanine green angiography before treatment. The CNV subsided after treatment. However, a large lacquer crack underlying a subretinal hemorrhage was formatted in the macula of the treated eye soon after PDT.


CONCLUSIONS
Although the chorioretinal damage produced by PDT is minimal, it is enough to create, directly or indirectly, the basis for the formation of a lacquer crack in an eye with pathologic myopia.
Ladas
I D
ID
Department of Ophthalmology, Medical School of Athens University, Athens, Greece. Ladas@ath.forthnet.gr
Moschos
M M
MM
Rouvas
A A
AA
Karagiannis
D A
DA
Kokolakis
S N
SN
D000328:Adult; D000792:Angiography; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects*; D011166:Porphyrins / Q000009:adverse effects*; D012167:Retinal Perforations / Q000139:chemically induced* / Q000175:diagnosis; D000077362:Verteporfin
D004396:Coloring Agents; D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin; D007208:Indocyanine Green