Halogenating enzymes in the biosynthesis of antibiotics.
Using blot hybridization, it has been shown that microorganisms producing halogen-containing antibiotics--Pseudomonas pyrrocinia, P. aureofaciens ACN, P. aureofaciens Pa1, P. fluorescens CHA0, Actinoplanes sp., Kitasatasporia sp., Sacharothrix aerocolonigenes, Actinomadura melliaura, and Streptomyces albogriseolus--contain the genes of the halogenating enzymes related to tryptophan-7-halogenase and monodechloroaminopyrrolnitrin halogenase from P. fluorescens BL 915.
Burd
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Grodno State University, Grodno, 230015, Belarus'. burd@mail.grsu.grodno.by
Van Pee
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KH
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000737:chemistry; D001419:Bacteria / Q000201:enzymology* / Q000235:genetics*; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D006219:Halogens / Q000378:metabolism*; D009693:Nucleic Acid Hybridization; D010088:Oxidoreductases / Q000235:genetics / Q000378:metabolism
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D006219:Halogens; D010088:Oxidoreductases; C407364:monodechloroaminopyrrolnitrin halogenase