title: A facile diastereoselective synthesis of functionalized 1,2,3-trisubstituted benzocyclopentenes through the cycloaddition of bis(phenylsulfonyl)iodonium ylides to cyclic alkenes.
abstract: The thermal cycloaddition of beta-disulfonyl iodonium ylides to cyclic alkenes affords exclusively 1,2,3-trisubstituted cis(1,2)/cis(2,3)-configured benzocyclopentenes by an electrophilic attack of the ylide on the olefinic double bond. This unsual transformation provides a convenient and direct method for the diastereoselective synthesis of functionalized bicyclo[3.3.0]octanes (characteristic structural units contained in polyquinane natural products), when cyclopentenes are used as cycloalkene partner.
authors: Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.
authors: Waldemar
authors: W
authors: Adam
authors: Efstathios P
authors: EP
authors: Gogonas
authors: Lazaros P
authors: LP
authors: Hadjiarapoglou