The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction.
The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/). Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.
Hediger
Matthias A
MA
Membrane Biology Program and Renal Division, Brigham and Women's Hospital, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. mhediger@rics.bwh.harvard.edu
Romero
Michael F
MF
Peng
Ji-Bin
JB
Rolfs
Andreas
A
Takanaga
Hitomi
H
Bruford
Elspeth A
EA
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D006801:Humans; D026901:Membrane Transport Proteins / Q000502:physiology*
D026901:Membrane Transport Proteins