Allergic and nonallergic drug reactions.
Allergic drug reactions may be difficult to distinguish from nonallergic reactions. In this article, we review a pragmatic approach to the management of adverse drug reactions on the basis of knowledge of the classification and patterns of these reactions. Algorithms for management of patients with a previous adverse drug reaction who require treatment for the same indication, and the approach to a patient who experiences a drug reaction while on multiple drugs, are presented.
Yates
Anne B
AB
Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA. ayates@ped.umsmed.edu
deShazo
Richard D
RD
D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D001241:Aspirin / Q000009:adverse effects; D002511:Cephalosporins / Q000009:adverse effects; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000517:prevention & control; D003287:Contrast Media / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D010406:Penicillins / Q000009:adverse effects; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000517:prevention & control; D012307:Risk Factors
D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002511:Cephalosporins; D003287:Contrast Media; D010406:Penicillins; D001241:Aspirin