Comparison of solid-phase extraction and micro-solid-phase extraction for liquid chromatography/mass spectrometry analysis of pesticides in water samples.
Our recent on-line solid-phase extraction (SPE) device for micro-liquid chromatography, known as micro-solid-phase extraction (microSPE), was compared with traditional SPE for the analysis, from aqueous samples, of 4 pesticides belonging to different classes. Two different kinds of adsorbents, C18 and graphitized carbon black, were tested. A 2-stage ion trap mass spectrometer, equipped with homemade microflow electrospray ion (ESI) source, was used. Detection limits with a signal-to-noise ratio of 3:1 for both extraction methods were in the range of 0.1 microg/L for all compounds. However, better recoveries were obtained when microSPE traps were used.
Famiglini
Giorgio
G
University of Urbino, Istituto di Scienze Chimiche F. Bruner, P. Rinascimento 6, 61029 Urbino, Italy. g.famiglini@uniurb.it
Trufelli
Helga
H
Pierini
Elisabetta
E
De Simoni
Elisa
E
Mangani
Filippo
F
Cappiello
Achille
A
D000327:Adsorption; D001542:Benomyl / Q000032:analysis; D002138:Calibration; D002853:Chromatography, Liquid / Q000379:methods*; D017022:Flow Injection Analysis; D008714:Methiocarb / Q000032:analysis; D008724:Methomyl / Q000032:analysis; D008904:Miniaturization; D009946:Organothiophosphorus Compounds / Q000032:analysis; D010575:Pesticides / Q000032:analysis*; D011786:Quality Control; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014867:Water / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D009946:Organothiophosphorus Compounds; D010575:Pesticides; D014874:Water Pollutants, Chemical; D014867:Water; D008724:Methomyl; D008714:Methiocarb; D001542:Benomyl; C005828:methidathion