[Innate immunity, Toll receptor and sepsis].
The innate immune response is the first line of defense against infection. Toll-like receptors (TLRs) recognize bacterial lipopolysaccharide and other pathogen-associated molecular patterns (PAMPs). Intracellular signals initiated by interaction between Toll receptors and specific PAMPs results in inflammatory response. Sepsis and septic shock are the result of an exaggerated inflammatory systemic response induced by innate immune dysregulation.
Carrillo-Esper
Raúl
R
Postgrado de Medicina del Enfermo en Estado Crítico, Servicio de Terapia Intensiva HCSAE PEMEX. seconsapcma@mail.medinet.net.mx
D000818:Animals; D004330:Drosophila; D029721:Drosophila Proteins; D006801:Humans; D007113:Immunity, Innate; D008562:Membrane Glycoproteins / Q000276:immunology*; D011956:Receptors, Cell Surface / Q000276:immunology*; D018805:Sepsis / Q000276:immunology*; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors
D029721:Drosophila Proteins; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors; C495341:tehao protein, Drosophila