title: Direct mass spectrometric monitoring of solid phase organic syntheses.
abstract: Direct on-bead monitoring of solid-phase reactions is possible with soft laser desorption time-of-flight mass spectrometry (SLD-TOF MS) without prior cleavage from the resin if photocleavable phenacyl ester or o-nitroveratryl linker groups are employed.
authors: Max-Planck-Institut für molekulare Physiologie, Abt. Chemische Biologie, Otto-Hahn-Strasse 11, D-44227 Dortmund, Germany.
authors: Jantje M
authors: JM
authors: Gerdes
authors: Herbert
authors: H
authors: Waldmann
mesh_terms: D013058:Mass Spectrometry / Q000379:methods; D009930:Organic Chemicals / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D009930:Organic Chemicals