Systems biology in neuroscience: bridging genes to cognition.
Systems biology is a new branch of biology aimed at understanding biological complexity. Genomic and proteomic methods integrated with cellular and organismal analyses allow modelling of physiological processes. Progress in understanding synapse composition and new experimental and bioinformatics methods indicate the synapse is an excellent starting point for global systems biology of the brain. A neuroscience systems biology programme, organized as a consortium, is proposed.
Grant
Seth G N
SG
Division of Neuroscience, 1 George Square, Edinburgh EH8 9JZ, UK. seth.grant@ed.ac.uk
D000818:Animals; D003071:Cognition / Q000502:physiology*; D006801:Humans; D008967:Molecular Biology / Q000379:methods; D016571:Neural Networks, Computer; D009488:Neurosciences / Q000379:methods*; D013598:Systems Theory