title: Psychiatric disorder and quality of life in patients awaiting lung transplantation.
abstract: OBJECTIVE
  To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation.
  
  
  METHODS
  Duke University Medical Center/Lung Transplantation Program.
  
  
  METHODS
  One hundred patients with end-stage pulmonary disease listed for lung transplantation.
  
  
  RESULTS
  Twenty-five percent (n = 25) of the sample met diagnostic criteria for at least one current mood or anxiety disorder. Controlling for age, gender, ethnicity, percentage of predicted FEV, and lung disease diagnosis, patients with a current psychiatric diagnosis reported poorer general quality of life (p < 0.0001), poorer disease-specific quality of life (p < 0.0001), greater shortness of breath (p = 0.01), more symptoms of psychological distress (p < 0.0001), lower levels of social support (p < 0.0001), and fewer positive health habits (p < 0.04) than their counterparts without a psychiatric diagnosis.
  
  
  CONCLUSIONS
  Psychiatric comorbidity affects a significant portion of patients awaiting lung transplantation and is associated with decreased health-related quality of life.
authors: Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
authors: Priti I
authors: PI
authors: Parekh
authors: James A
authors: JA
authors: Blumenthal
authors: Michael A
authors: MA
authors: Babyak
authors: Kari
authors: K
authors: Merrill
authors: Robert M
authors: RM
authors: Carney
authors: R Duane
authors: RD
authors: Davis
authors: Scott M
authors: SM
authors: Palmer
mesh_terms: D001008:Anxiety Disorders / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006304:Health Status; D006801:Humans; D008171:Lung Diseases / Q000523:psychology / Q000601:surgery; D016040:Lung Transplantation / Q000523:psychology*; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis*; D008875:Middle Aged; D019964:Mood Disorders / Q000175:diagnosis / Q000209:etiology; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D013315:Stress, Psychological / Q000209:etiology; D011795:Surveys and Questionnaires; D014850:Waiting Lists