Multiple trichoepitheliomas in a mother and daughter.
A 38-year-old mother and her 8-year-old daughter presented with multiple facial papules. In both cases, the papules had started to develop at about the age of 4-5 years. Biopsy of one of the mother's papules revealed a trichoepithelioma. With time the lesions had become less obvious in the mother, so she and her daughter elected to have no treatment. Both mother and daughter were otherwise well. However, there have been rare reports of multiple trichoepitheliomas being associated with systemic conditions. Multiple trichoepitheliomas are inherited in an autosomal dominant manner and have been mapped to chromosome 9p21.
Crotty
Kerry
K
The Childrens Hospital at Westmead, Westmead, New South Wales, Australia.
Dutta
Bishnu
B
Hogan
Peter
P
D000328:Adult; D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology*; D002648:Child; D005148:Facial Dermatoses / Q000235:genetics* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D010375:Pedigree; D018570:Risk Assessment; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology*