Treatment of severe neuroleptic-induced tardive torticollis.
BACKGROUND: The aim of this paper is to describe a case of severe neuroleptic-induced tardive torticollis successfully treated with a combination of clozapine, clonazepam and botulinum toxin-A. CASE REPORT: The patient, a 30-year old man with a seven-year history of delusional disorder experienced severe right torticollis with painful tightness of the neck and elevation of the shoulder. At this time he was receiving haloperidol 20 mg, trifluoperazine 5 mg, zuclopenthixol 20 mg and biperidine 4 mg daily. The combination therapy with clozapine and clonazepam and the long-term use of botulinum toxin-A resulted in a complete remission of dystonic movements. CONCLUSIONS: The present observations provide evidence indicating that this combination therapy may be of benefit in patients with severe neuroleptic-induced tardive torticollis.
Havaki-Kontaxaki
Beata J
BJ
Department of Psychiatry, University of Athens, Eginition Hospital, Athens, Greece. bkont@cc.uoa.gr
Kontaxakis
Vassilis P
VP
Margariti
Maria M
MM
Paplos
Konstantinos G
KG
Christodoulou
George N
GN