Dermatomyositis developing in the first trimester of pregnancy.
Dermatomyositis in pregnancy is rare. Pregnancy may be a precipitating factor at the onset or may develop during the course of dermatomyositis, which would exacerbate disease activity. In this study, we report a 22-year-old female patient who developed generalized skin rash and progressive muscle weakness in the twelfth week of pregnancy. She was diagnosed with dermatomyositis and underwent therapeutic abortion, due to the high fetal mortality rate of the disease when developed in the first trimester. Her symptoms improved with treatment of intravenous immunoglobulin and a high dose of corticosteroids.
Park
In Whee
IW
Department of Allergy and Rheumatology, Ajou University School of Medicine, San-5, Woncheon-dong, Paldal-gu, Suwon, 442-721, Korea.
Suh
Yu Jin
YJ
Han
Jae Ho
JH
Shin
Yoo Seob
YS
Choi
Jeong Hee
JH
Park
Hae Sim
HS
Suh
Chang Hee
CH
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003882:Dermatomyositis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D011239:Prednisolone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications; D011261:Pregnancy Trimester, First; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D011239:Prednisolone