title: Successful treatment of vancomycin resistant Enterococcus faecium mediastinitis associated with left ventricular assist devices.
abstract: We present 2 cases of vancomycin-resistant Enterococcus faecium mediastinitis associated with left ventricular assist devices in the setting of heart transplantation. Despite complicated operative courses and deep infection secondary to antimicrobial resistant organisms, both patients were successfully treated and have remained infection free in the long term.
authors: Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
authors: Preeti N
authors: PN
authors: Malani
authors: David B S
authors: DB
authors: Dyke
authors: Francis D
authors: FD
authors: Pagani
authors: Wendy S
authors: WS
authors: Armstrong
authors: Carol E
authors: CE
authors: Chenoweth
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000601:surgery; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D016984:Enterococcus faecium / Q000187:drug effects* / Q000302:isolation & purification; D005260:Female; D005500:Follow-Up Studies; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents