Allylation of donor--acceptor cyclopropanes.
[reaction: see text] Direct allylation of glycal-derived donor-acceptor cyclopropanes has been achieved with TiCl(4) activation followed by addition of allyltrimethylsilane. The alpha diastereomer is the major product, with selectivities ranging from 3:1 to 10:1 and yields around 80%.
Yu
Ming
M
Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
Pagenkopf
Brian L
BL
D003521:Cyclopropanes / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014297:Trimethylsilyl Compounds / Q000737:chemistry
D003521:Cyclopropanes; D014297:Trimethylsilyl Compounds; C440774:allyltrimethylsilane