Effect of testosterone therapy on QT dispersion in men with heart failure.
The effects of testosterone on cardiac electrophysiology are poorly described. In this study we report the effect of physiologic testosterone therapy in 2 cohorts of men, the first with stable coronary disease and the second with congestive heart failure. Testosterone reduced QT dispersion in the heart failure cohort; no other effects were observed.
Malkin
Chris J
CJ
Department of Cardiology, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Morris
Paul D
PD
Pugh
Peter J
PJ
English
Kate M
KM
Channer
Kevin S
KS
D000279:Administration, Cutaneous; D000368:Aged; D000728:Androgens / Q000494:pharmacology*; D015331:Cohort Studies; D003327:Coronary Disease / Q000503:physiopathology*; D004311:Double-Blind Method; D004562:Electrocardiography / Q000187:drug effects*; D006333:Heart Failure / Q000503:physiopathology*; D020249:Hormone Replacement Therapy; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D013739:Testosterone / Q000494:pharmacology*
D000728:Androgens; D013739:Testosterone