title: Differentially functionalized diamines as novel ligands for the NPY2 receptor.
abstract: The synthesis of novel ligands for the NPY(2) receptor using solid phase split pool methodology is described. One of the analogues, diamine 16, was found to be a potent NPY(2) binder.
authors: Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT 06492, USA.
authors: Charles J
authors: CJ
authors: Andres
authors: Ildiko
authors: I
authors: Antal Zimanyi
authors: Milind S
authors: MS
authors: Deshpande
authors: Lawrence G
authors: LG
authors: Iben
authors: Katharine
authors: K
authors: Grant-Young
authors: Gail K
authors: GK
authors: Mattson
authors: Weixu
authors: W
authors: Zhai
mesh_terms: D000215:Acylation; D045744:Cell Line, Tumor; D003959:Diamines / Q000138:chemical synthesis / Q000378:metabolism*; D006801:Humans; D020128:Inhibitory Concentration 50; D008024:Ligands; D009447:Neuroblastoma / Q000378:metabolism; D011869:Radioligand Assay; D017476:Receptors, Neuropeptide Y / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D003959:Diamines; D008024:Ligands; D017476:Receptors, Neuropeptide Y; C095889:neuropeptide Y2 receptor