title: Massive tongue swelling following the use of synthetic saliva.
abstract: A 5-year-old boy with cerebral palsy and severe learning difficulties developed massive tongue swelling of sudden onset following the use of synthetic saliva. Acute airway obstruction and severe stridor ensued which required tracheal intubation and transfer to paediatric intensive care. The child was treated with intravenous steroids, antihistamines and epinephrine. With cessation of synthetic saliva, the swelling gradually resolved and the child was extubated on day 5.
authors: Department of Paediatric Intensive Care, Royal Manchester Children's Hospital, Manchester, UK. v_kandala@hotmail.com
authors: Vijay
authors: V
authors: Kandala
authors: Stephen
authors: S
authors: Playfor
mesh_terms: D000402:Airway Obstruction / Q000139:chemically induced* / Q000628:therapy; D000799:Angioedema / Q000139:chemically induced* / Q000188:drug therapy; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002547:Cerebral Palsy / Q000150:complications; D002675:Child, Preschool; D002744:Chlorpheniramine / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007442:Intubation, Intratracheal; D008297:Male; D012135:Respiratory Sounds / Q000209:etiology; D012464:Saliva, Artificial / Q000009:adverse effects*; D014059:Tongue / Q000187:drug effects / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D006634:Histamine H1 Antagonists; D012464:Saliva, Artificial; D002744:Chlorpheniramine; D003907:Dexamethasone; D006854:Hydrocortisone; D004837:Epinephrine