Deciphering the gene expression profile of long-lived snell mice.
In a recent publication, gene expression profiling experiments for the long-lived Snell dwarf mouse were reported. In this Perspective, the author argues that although the authors have developed a solid analytical approach, further refinements are needed to produce robust conclusions.
Becker
Kevin G
KG
DNA Array Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. beckerk@grc.nia.nih.gov
D000818:Animals; D020869:Gene Expression Profiling; D008136:Longevity / Q000235:genetics*; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D015203:Reproducibility of Results