Salivary gland basal cell adenocarcinoma: a report of cases in a cat and two dogs.
Basal cell adenocarcinoma of the salivary gland is described in a cat and two dogs; tumour tissue was characterized by cords and islands of epithelial cells with a distinct basal layer. The tumours were stained by various immunohistochemical methods. In addition to positive staining with cytokeratin 14 and pancytokeratin (CKs 5, 6, 8, 17 and 19), there was also staining with Jack bean agglutinin A (ConA) and soya bean agglutinin (SBA); this occurs in many other types of salivary gland tumours and is a feature of normal salivary gland acinar cells. In one dog there was also staining with SBA. This is the first report of this tumour in domestic animals; the immunohistochemical characteristics did not distinguish it from other salivary gland tumours.
Sozmen
M
M
Comparative Pathology Laboratory, Department of Clinical Veterinary Science, Division of Veterinary Pathology, Infection and Immunity, University of Bristol Veterinary School, Langford, Bristol, BS40 5DU, UK.
Brown
P J
PJ
Eveson
J W
JW
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D012469:Salivary Glands / Q000473:pathology