title: [Therapy with cytokines and thymic factors in a complicated case of common variable immunodeficiency].
abstract: A case with common variable immunodeficiency associated to hyperprolactinaemia and severe damage of mucosal defenses is reported, in which humoral and cellular response was widely explored. The impact of the cytokines therapy was analyzed as complementary schedule to the conventional therapy with gammaglobuline. Immune response to the treatment was long-time evaluated in relation with therapeutic interventions. Combination of alpha 2 b-IFN, thymic factors, gammaglobuline and GM-CSF was a good alternative to treat complicated common variable immunodeficiency.
authors: Laboratorio de Inmunología, División de Posgrado, Escuela de Medicina Ignacio Chávez, Universidad Michoacana, San Nicolás de Hidalgo. arorozco@hotmail.com
authors: Alain R
authors: AR
authors: Rodríguez Orozco
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001562:Benzimidazoles / Q000627:therapeutic use; D001971:Bromocriptine / Q000627:therapeutic use; D017074:Common Variable Immunodeficiency / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000188:drug therapy; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D019804:Mesalamine / Q000627:therapeutic use; D009853:Omeprazole / Q000031:analogs & derivatives; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D064750:Rabeprazole; D011899:Ranitidine / Q000627:therapeutic use; D011994:Recombinant Proteins; D013844:Thiazoles / Q000627:therapeutic use*; D053778:Thiazolidines; D014165:Transfer Factor / Q000627:therapeutic use*; D014815:Vitamins / Q000627:therapeutic use; D005719:gamma-Globulins / Q000627:therapeutic use*
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D013844:Thiazoles; D053778:Thiazolidines; D014165:Transfer Factor; D014815:Vitamins; D005719:gamma-Globulins; D064750:Rabeprazole; D001971:Bromocriptine; D019804:Mesalamine; C064893:pidotimod; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D011899:Ranitidine; D009853:Omeprazole; D011761:Pyrrolidonecarboxylic Acid