title: Direct stent implantation using the EXPRESS Coronary Stent System: results of a multi-center feasibility study.
abstract: The aim of this prospective, multicenter, single arm study was to assess the safety and feasibility of EXPRESS Coronary Stent implantation in native coronary arteries without balloon predilatation. Forty-two patients with de novo or restenotic lesions were enrolled, of which 38 were eligible for analysis. The coronary lesions were predominantly complex, occurring in arteries with a mean reference diameter of 2.80 +/- 0.49 mm. Technical and procedural success were achieved in 89.5% and 84% of the cases respectively. The mean minimal lumen diameter increased from 1.08 +/- 0.26 mm to 2.55 +/- 0.44 mm and diameter stenosis decreased from 61 +/- 7% to 13 +/- 8%. The primary endpoint of major adverse cardiac events at 30 days was 2.6% and was limited to only one event (target vessel revascularization, nontarget lesion). No other MACE were observed during the three-month follow-up period. Based on the findings of this study, direct stenting with the EXPRESS Stent appears feasible and is well tolerated.
authors: Internistische Klinik Dr. Müller, Herzkatheterlabor Cardiology Associates, Munich, Germany. silber@med.de
authors: Sigmund
authors: S
authors: Silber
authors: Eberhard
authors: E
authors: Grube
authors: Jean
authors: J
authors: Marco
authors: Gilles
authors: G
authors: Grollier
authors: Marie-Claude
authors: MC
authors: Morice
authors: Patrick
authors: P
authors: Serruys
authors: Michael
authors: M
authors: Cobaugh
authors: William
authors: W
authors: Wijns
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D004867:Equipment Design; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D009204:Myocardial Revascularization; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome