Use of recombinant factor VIIa for bleeding in children with Glanzmann thrombasthenia.
Glanzmann thrombasthenia is a very rare inherited platelet function disorder in which bleeding may be extremely difficult to stop. Recombinant factor VIIa is one of the alternative treatments for bleeding. The authors report here their experience with the use of factor VIIa, which may be useful for arresting bleeding in Glanzmann thrombasthenia.
Cağlar
Kudret
K
Hacettepe University, Faculty of Medicine, Department of Pediatrics, Pediatric Oncology Unit, Ankara, Turkey.
Cetinkaya
Ahmet
A
Aytaç
Selin
S
Gümrük
Fatma
F
Gürgey
Aytemiz
A
D000208:Acute Disease; D002648:Child; D002944:Circumcision, Male / Q000009:adverse effects; D004844:Epistaxis / Q000188:drug therapy / Q000209:etiology; D005167:Factor VII / Q000627:therapeutic use*; D015942:Factor VIIa; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D019106:Postoperative Hemorrhage / Q000188:drug therapy / Q000209:etiology; D011994:Recombinant Proteins / Q000627:therapeutic use*; D013915:Thrombasthenia / Q000097:blood / Q000150:complications / Q000188:drug therapy*
D011994:Recombinant Proteins; D005167:Factor VII; C103587:recombinant FVIIa; D015942:Factor VIIa