title: Transmission of Helicobacter pylori infection in families of preschool-aged children from Minas Gerais, Brazil.
abstract: We evaluated the role of the family in the transmission of Helicobacter pylori infection in preschool-aged children from a rural district in the State of Minas Gerais, Brazil. Sixty-six families (66 index children, 63 mothers, 60 fathers and 134 siblings), defined as at least one parent living in the same household with at least one offspring up to 8 years old, were studied. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression controlling for age, gender, number of children in household and H. pylori status of the father, mother and siblings. The prevalence of the infection was 69.7% (469 of 673) and it increased with age (P < 0.001). Positive mothers were a strong and independent risk factor for infection (OR 22.70; 95% CI 2.31-223.21). Positive siblings were also positively associated with infection (OR 1.81; 95% CI 1.01-3.30).
authors: Laboratory of Research in Bacteriology, Faculdade de Medicina, UFMG, Belo Horizonte, Brazil. garocha@medicina.ufmg.br
authors: Gifone Aguiar
authors: GA
authors: Rocha
authors: Andreia Maria Camargos
authors: AM
authors: Rocha
authors: Luciana Diniz
authors: LD
authors: Silva
authors: Adriana
authors: A
authors: Santos
authors: Ana Carolina Dias
authors: AC
authors: Bocewicz
authors: Renata de Magalhães
authors: Rde M
authors: Queiroz Rd
authors: Jeffrey
authors: J
authors: Bethony
authors: Andréa
authors: A
authors: Gazzinelli
authors: Rodrigo
authors: R
authors: Corrêa-Oliveira
authors: Dulciene Maria Magalhães
authors: DM
authors: Queiroz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005190:Family; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology / Q000635:transmission*; D016480:Helicobacter pylori; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012423:Rural Health; D016036:Seroepidemiologic Studies