title: [Results of long-term administration of propranolol to patients with ischemic heart disease].
abstract: As many as 314 patients with functional class I-III ischemic heart disease (IHD) who had been placed on a long-term (3-year) monotherapy with propranolol were examined. Under a long-term administration of a beta-adrenoblocking agent no suppression has been seen of the contractile capability of the myocardium; there is noted an improvement in hemorheologic disturbances and a significantly greater improvement in the clinical course of the illness--it has been found out the therapy prevents transformation of angina of high effort to angina of low effort.
authors: M V
authors: MV
authors: Bychko
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy / Q000503:physiopathology; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D017202:Myocardial Ischemia / Q000188:drug therapy*; D011433:Propranolol / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol