Inhibitory interhemispheric visuovisual interaction in motion perception.
Findings of an earlier functional magnetic resonance imaging (fMRI) study that coherent motion stimulation of the right or left visual hemifield exhibited negative signal changes (deactivations) in the primary visual cortex and the lateral geniculate nucleus contralateral to the stimulated hemisphere were evaluated to determine the functional significance of this contralateral inhibition of the visual system. Fourteen subjects participated in a psychophysical study on the perception of single object motion (0.4 degrees /s) in one visual hemifield with or without concurrent coherent motion stimulation of the contralateral hemifield. Mean detection times for horizontal object motion (0.5 +/- 0.19 vs. 0.61 +/- 0.22 s) and vertical object motion (0.53 +/- 0.19 vs. 0.72 +/- 0.34 s) were significantly prolonged during concurrent motion pattern stimulation in the contralateral hemifield. These data support the interpretation that the deactivation of neuronal activity in the visual system found by fMRI is associated with a functional decrement in the sensitivity needed to perceive motion and may reflect transcallosal attentional shifts between the two hemispheres.
Brandt
Thomas
T
Department of Neurology, Ludwig-Maximilians University, Klinikum Grosshadern, 81377 Munich, Germany. thomas.brandt@nro.med.uni-muenchen.de
Marx
Esther
E
Stephan
Thomas
T
Bense
Sandra
S
Dieterich
Marianne
M
D000328:Adult; D005260:Female; D005829:Geniculate Bodies / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009039:Motion Perception / Q000502:physiology*; D011601:Psychophysics; D014793:Visual Cortex / Q000502:physiology*