title: Switching between novel samarium(II)-mediated cyclizations by a simple change in alcohol cosolvent.
abstract: Gamma,delta-unsaturated ketones undergo two very different stereoselective cyclization reactions mediated by samarium(II) iodide depending upon the alcohol cosolvent used in the reaction. Switching between an unprecedented aldol spirocyclization and a novel cyclobutanol-forming process can be achieved simply by changing the alcohol cosolvent from methanol to tert-butyl alcohol. [reaction: see text]
authors.affiliation: Department of Chemistry, The Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.
authors.forename: Thomas K
authors.initials: TK
authors.lastname: Hutton
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Muir
authors.forename: David J
authors.initials: DJ
authors.lastname: Procter