title: Molecular recognition of alkylammonium contact ion-pairs using a ditopic receptor.
abstract: A ditopic, macrobicyclic receptor with adjacent anion and cation binding sites is able to distinguish between various monoalkylammonium salts by binding them as contact ion-pairs. The affinity for linear n-propylammonium chloride is at least 2 orders of magnitude greater than that for n-propylammonium acetate, n-propylammonium p-toluenesulfonate, and branched isopropylammonium chloride. An X-ray structure of the receptor complexed with methylammonium chloride illuminates the basis of the molecular recognition.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556-5670, USA. smith.115@nd.edu
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Mahoney
authors.forename: John P
authors.initials: JP
authors.lastname: Davis
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Beatty
authors.forename: Bradley D
authors.initials: BD
authors.lastname: Smith