title: Evaluation of the Pall RC100 leucocyte removal filters and the effect of air introduction on its performance.
abstract: We evaluated the efficiency of Pall RC100 leucocyte removal filters in processing two units of concentrated red cells for transfusion. Our results show that the filter is very effective in processing the first unit. However, 32% (5/16) of the filters evaluated allowed a leak of substantial numbers of white cells towards the end of the transfusion of the second unit of blood. Air introduction experiments showed that as little as 2 ml of air in the filter may cause major deterioration of the filter function.
authors.affiliation: Department of Haematology, Leicester Royal Infirmary, Leicester, UK.
authors.forename: M
authors.initials: M
authors.lastname: Sivakumaran
authors.forename: K
authors.initials: K
authors.lastname: Ghosh
authors.forename: L
authors.initials: L
authors.lastname: Tan
authors.forename: J
authors.initials: J
authors.lastname: Revill
authors.forename: R M
authors.initials: RM
authors.lastname: Hutchinson
authors.forename: J K
authors.initials: JK
authors.lastname: Wood
mesh_terms: D000388:Air; D016913:Blood Component Transfusion; D004867:Equipment Design; D004868:Equipment Failure; D005374:Filtration / Q000295:instrumentation*; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation*; D007958:Leukocyte Count; D019095:Point-of-Care Systems