[Effect of alantone on mast cells and hemostasis].
In experiments on rats it has been shown that under the influence of alantone (50 mg/kg of the body weight daily during 30 days) a number and level of maturity of peritoneal and mesenteric mast cells increased, and blood clotting decreased. It might be important for the well-known ability of alantone to increase both the peripheral blood circulation and microcirculation.
Klymenko
M O
MO
Kharkiv Medical University.
Luchkova
M M
MM
Tatarko
S V
SV
Luchkov
A B
AB
D000284:Administration, Oral; D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D001241:Aspirin / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects*; D002452:Cell Count; D038143:Inula / Q000737:chemistry*; D007783:Lactones / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D008407:Mast Cells / Q000166:cytology / Q000187:drug effects*; D010529:Peritoneal Cavity / Q000166:cytology; D018517:Plant Roots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012717:Sesquiterpenes / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*
D007783:Lactones; D012717:Sesquiterpenes; D001241:Aspirin