title: Amphetamine poisoning in a dog: case report, literature review and veterinary medical perspectives.
abstract: Amphetamine abuse in human beings has increased, resulting in many reports of toxicity and death. In the US over 4 million people have abused amphetamines at least once, thus small animals are exposed to increased accidental poisoning risk. This report describes an acute amphetamine poisoning in a dog due to ingestion of 15 mg/kg fenproporex, leading to typical signs of catecholamines release and effects in different organ systems. Similar clinical and laboratory findings observed in human beings are reviewed and physiopathogenic mechanisms discussed, as well as the therapeutic approaches available in veterinary medicine.
authors.affiliation: Department of Veterinary Clinical Sciences, School of Veterinary Medicine and Animal Husbandry, São Paulo State University, CP 560, 1861 8-000, Botucatu, Brazil.
authors.forename: Pedro Paulo V P
authors.initials: PP
authors.lastname: Diniz
authors.forename: Marlos G
authors.initials: MG
authors.lastname: Sousa
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Gerardi
authors.forename: Mirela
authors.initials: M
authors.lastname: Tinucci-Costa
mesh_terms: D000662:Amphetamines / Q000506:poisoning*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000139:chemically induced / Q000175:diagnosis*; D004285:Dogs; D004638:Emergency Treatment / Q000662:veterinary; D017809:Fatal Outcome; D008297:Male; D011041:Poisoning / Q000175:diagnosis / Q000662:veterinary
chemical_list: D000662:Amphetamines; C026013:fenproporex