title: Neurogenetics: single gene disorders.
abstract: The advent of molecular biology has changed the way in which neurological illnesses are classified, and the single genes causing a number of disorders have been identified. In addition, techniques such as linkage analysis and DNA sequencing have resulted in greater understanding of multi-gene diseases. This review covers some of the molecular tools and animal models used for genetic analysis and for DNA based diagnosis, and a brief survey of information available on the internet.
authors.affiliation: Division of Neurology, Cedars-Sinai Medical Center, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. pulst@cshs.org
authors.forename: S-M
authors.initials: SM
authors.lastname: Pulst
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005821:Genetic Techniques; D006801:Humans; D033181:Information Dissemination; D020407:Internet; D009422:Nervous System Diseases / Q000235:genetics*