Death by quinine.
We report a case of a man with a 9.75 g ingestion of quinine. The patient presented with recurrent pulseless wide complex tachycardia for which he received sodium bicarbonate, defibrillation and overdrive mechanical pacing. Despite treatment, the patient died. Quinine is still available for the treatment of leg cramps and drug-resistant malaria. In overdose, quinine affects multiple organ systems, including vision, hearing, the cardiovascular, and renal systems. We review the current approach to quinine intoxication.
Morrison
Lisa D
LD
Section of Emergency Medicine, Louisiana State University, New Orleans, Louisiana, USA.
Velez
Larissa I
LI
Shepherd
Greene
G
Bey
Tareg
T
Benitez
Fernando L
FL
D000328:Adult; D003937:Diagnosis, Differential; D062787:Drug Overdose / Q000175:diagnosis; D004562:Electrocardiography; D004638:Emergency Treatment; D017809:Fatal Outcome; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011803:Quinine / Q000506:poisoning*; D013610:Tachycardia / Q000139:chemically induced / Q000503:physiopathology
D011803:Quinine