Most human isolates of Mycobacterium avium Mav-A and Mav-B are strong producers of hemolysin, a putative virulence factor.
Hemolysin was quantified in 58 isolates of Mycobacterium avium from human, animal, and environmental sources. Human Mav-A and Mav-B isolates were the strongest producers; in contrast, animal and environmental Mav-A isolates and human, animal, and environmental Mav-C organisms were low-level producers. Hemolysin production was not restricted to isolates causing invasive infections.
Rindi
Laura
L
Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia, ed Epidemiologia, Università di Pisa, I-56127 Pisa, Italy.
Bonanni
Daniela
D
Lari
Nicoletta
N
Garzelli
Carlo
C
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D000818:Animals; D006460:Hemolysin Proteins / Q000032:analysis*; D006801:Humans; D009162:Mycobacterium avium / Q000302:isolation & purification* / Q000472:pathogenicity*; D015269:Mycobacterium avium Complex / Q000302:isolation & purification* / Q000472:pathogenicity*; D014376:Tuberculosis / Q000382:microbiology; D014774:Virulence
D006460:Hemolysin Proteins