title: Antioxidative properties of the essential oil from Pinus mugo.
abstract: The essential oil from Pinus mugo (PMEO) was tested on its antioxidative capacity. For this purpose, several biochemical test systems were chosen (e.g., the Fenton System, the xanthine oxidase assay, or the copper-induced oxidation of low-density lipoprotein (LDL)). The results show that there is moderate or weak antioxidative activity when tested in aqueous environments, like in the Fenton system, xanthine oxidase induced superoxide radical formation, or in the HOCl driven fragmentation of 1-aminocyclopropane-1-carboxylic acid (ACC). In contrast, when tested in more lipophilic environments (e.g., the ACC-cleavage by activated neutrophils in whole blood) the PMEO exhibits good antioxidative activity. PMEO does also show good antioxidative capacity in another lipophilic test system (i.e., the copper induced oxidation of LDL). Some components of PMEO (i.e., Delta(3)-carene, camphene, alpha-pinene, (+)-limonene and terpinolene) were also tested. As the PMEO, they showed weak or no antioxidant activity in aqueous environments, but some of them were effective antioxidants regarding ACC-cleavage by activated neutrophils in whole blood or copper-induced LDL-oxidation. Terpinolene, a minor component of PMEO, exhibited remarkable protection against LDL-oxidation.
authors.affiliation: Institute of Vegetable Science, Life Science Center Weihenstephan, TUM, Dürnast 2, 85350 Freising, Germany. johanna.grassmann@wzw.tum.de
authors.forename: Johanna
authors.initials: J
authors.lastname: Grassmann
authors.forename: Susanne
authors.initials: S
authors.lastname: Hippeli
authors.forename: Renate
authors.initials: R
authors.lastname: Vollmann
authors.forename: Erich F
authors.initials: EF
authors.lastname: Elstner
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D003300:Copper / Q000737:chemistry; D005030:Ethylenes / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008077:Lipoproteins, LDL / Q000737:chemistry; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism; D009822:Oils, Volatile / Q000494:pharmacology*; D010084:Oxidation-Reduction; D028223:Pinus / Q000737:chemistry*; D010938:Plant Oils / Q000494:pharmacology*; D013729:Terpenes / Q000494:pharmacology; D014969:Xanthine Oxidase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005030:Ethylenes; D008077:Lipoproteins, LDL; D009822:Oils, Volatile; D010938:Plant Oils; D013729:Terpenes; D003300:Copper; C036216:ethylene; D014969:Xanthine Oxidase