Contact orofacial granulomatosis caused by delayed hypersensitivity to gold and mercury.
Orofacial granulomatosis, an entity with characteristic clinicopathologic features, is thought to be a reactive process. The authors describe orofacial granulomatosis associated with contact allergy to gold in dental crowns in one patient and a possible allergic contact reaction to mercury from dental fillings in another one. Thus allergic contact dermatitis to the metals gold and mercury should be considered as a possible etiologic agent of orofacial granulomatosis.
Lazarov
Aneta
A
Contact Dermatitis Clinic, Sapir Medical Center, Meir Hospital, Kfar Saba 44281, Israel. lazarov1@netvision.net.il
Kidron
Dvora
D
Tulchinsky
Zeev
Z
Minkow
Benny
B
D000328:Adult; D000368:Aged; D003442:Crowns; D003723:Dental Amalgam / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D003877:Dermatitis, Contact / Q000209:etiology*; D005148:Facial Dermatoses / Q000209:etiology*; D005260:Female; D006047:Gold Alloys / Q000009:adverse effects*; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008047:Lip Diseases / Q000209:etiology; D017669:Mercury Compounds / Q000009:adverse effects*; D009059:Mouth Diseases / Q000209:etiology*
D006047:Gold Alloys; D017669:Mercury Compounds; D003723:Dental Amalgam