title: [Myocardial infarction. Population case-fatality in seven Spanish autonomous communities: the IBERICA Study].
abstract: OBJECTIVE
  The magnitude of the problem of myocardial infarction (MI) is better understood by assessing the population case-fatality than by analyzing only the number of patients attending hospitals.
  
  
  METHODS
  Our data come from the IBERICA Study (Investigation, Specific Search and Registry of Acute Myocardial Ischemic Syndrome). Twenty eight-day MI population case-fatality is described in the population aged 25 to 74 years during 1997 and 1998 in the following Spanish autonomous communities: Castilla-La Mancha (Toledo and Albacete), Catalonia (Girona), Valencia Community (Valencia), Balearic Islands (Majorca), Murcia, Navarra and Basque Country. The relationship between case-fatality and other variables such as sex, age and geographic area is also analyzed.
  
  
  RESULTS
  A total of 10,660 MI cases were registered, 4,106 of whom died within the period of 28 days following the onset of symptoms (38.5%; CI 95%, 37.6-39.4%). The overall case-fatality was 37.0% (CI 95%, 35.9-38.0%) in men and 44.3% (CI 95%, 42.3-46.4%) in women. Death occurred out of hospitals in 2,869 (69.9%) cases. An increased case-fatality in women was associated with a higher in-hospital case-fatality (45% higher than men). The proportion of patients who died before reaching a hospital was similar in both genders. Classical symptoms of MI were more common among men than women (82.7% vs. 77.6%, p < 0,001). The interval between symptoms' onset and hospitalization was 30 minute longer among hospitalized women as compared with men (p < 0,001).
  
  
  CONCLUSIONS
  Population MI case-fatality is high in the seven Spanish autonomous communities studied. Approximately 2 out of 3 deaths occur without patients being able to reach a hospital. These results emphasize the importance of primary and secondary prevention measures and the necessity to design ready-access systems to defibrillation and resuscitation manoeuvres for patients with cardiopulmonary arrest.
authors.affiliation: Servicio de Epidemiología. Consejería de Sanidad y Consumo. Murcia. España. mjose.tormo@carm.es
authors.forename: José
authors.initials: J
authors.lastname: García
authors.forename: Roberto
authors.initials: R
authors.lastname: Elosua
authors.forename: María José
authors.initials: MJ
authors.lastname: Tormo Díaz
authors.forename: Covadonga
authors.initials: C
authors.lastname: Audicana Uriarte
authors.forename: Oscar
authors.initials: O
authors.lastname: Zurriaga
authors.forename: Antonio
authors.initials: A
authors.lastname: Segura
authors.forename: Miquel
authors.initials: M
authors.lastname: Fiol
authors.forename: Concepción
authors.initials: C
authors.lastname: Moreno-Iribas
authors.forename: Eva
authors.initials: E
authors.lastname: Alonso
authors.forename: Susana
authors.initials: S
authors.lastname: Bosch
authors.forename: Gemma
authors.initials: G
authors.lastname: Vega
authors.forename: Joan
authors.initials: J
authors.lastname: Sala
authors.forename: Jaume
authors.initials: J
authors.lastname: Marrugat
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality*; D012307:Risk Factors