title: [Clinical observation on xiehuo yangyin powder in treating 30 initial stage of toxic and diffuse goiter patients].
abstract: OBJECTIVE
  To observe the therapeutic effect of Xiehuo Yangyin powder (XHYY) in treating the initial stage of toxic and diffuse goiter (Graves' disease).
  
  
  METHODS
  Sixty patients were randomly divided into two groups, the treated group (n = 30) was treated with XHYY and methimazole, while the control group (n = 30) was treated with methimazole alone. The TCM syndrome score and thyroxin level in the two groups were compared and analyzed before, and 2 weeks, 12 weeks after treatment.
  
  
  RESULTS
  The syndrome score and thyroxin level in the treated group 2 weeks, 4 weeks, 12 weeks after treatment were reduced in comparing with before treatment, with the improvement better than those in the control group in the corresponding stages (P < 0.05).
  
  
  CONCLUSIONS
  The Chinese herbal medicine XHYY plus methimazole, in treating Graves' disease, could rapidly and effectively improve the patients' clinical symptoms and lower the thyroxin level, reduce the daily taken of methimazole.
authors.affiliation: Second Affiliated Hospital of Guiyang College of TCM, Guiyang 550002.
authors.forename: Xue-mei
authors.initials: XM
authors.lastname: Li
authors.forename: Yong-fen
authors.initials: YF
authors.lastname: Cao
authors.forename: Juan
authors.initials: J
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D013956:Antithyroid Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008713:Methimazole / Q000627:therapeutic use*; D008875:Middle Aged; D008517:Phytotherapy; D011208:Powders; D013974:Thyroxine / Q000097:blood
chemical_list: D013956:Antithyroid Agents; D004365:Drugs, Chinese Herbal; D011208:Powders; D008713:Methimazole; D013974:Thyroxine