title: Effect of beta-adrenoceptor blockade on cardiac activity in rats during postnatal ontogeny.
abstract: Electrical stimulation of the right stellate ganglion produces a positive chronotropic effect in 21-, 56-, and 100-day-old rats. The response of the heart rate to suprathreshold stimulation increased from the 21st to 100th day. By contrast, during beta-adrenoceptor blockade the heart rate response decreased. The data suggest that the role of beta-adrenoceptor in the regulation of cardiac chronotropic function increased with age.
authors.affiliation: Department of Anatomy, Physiology, and Human Health Protection, Kazan' State Pedagogical University.
authors.forename: T A
authors.initials: TA
authors.lastname: Anikina
authors.forename: G A
authors.initials: GA
authors.lastname: Bilalova
authors.forename: F G
authors.initials: FG
authors.lastname: Sitdikov
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000375:Aging; D000818:Animals; D001835:Body Weight; D004594:Electrophysiology; D005268:Femoral Vein / Q000378:metabolism; D006339:Heart Rate; D009206:Myocardium / Q000378:metabolism*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*; D013233:Stellate Ganglion / Q000473:pathology; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists; D011943:Receptors, Adrenergic, beta; D011433:Propranolol