Generic forms of low-molecular-weight heparins: some practical considerations.
This commentary briefly reviews the controversies of therapeutic and generic interchangeability, as they apply to the antithrombotic drug class called low-molecular-weight heparin (LMWH). Recommendations are prepared for the generic LMWH approval process by various regulatory bodies.
Leong
Wendy
W
Burnaby Research, University of British Columbia, Vancouver, B.C., Canada. wendy@leong.com
Hoppensteadt
Debra A
DA
D000925:Anticoagulants / Q000592:standards; D017277:Drug Approval; D016568:Drugs, Generic / Q000592:standards*; D006495:Heparin, Low-Molecular-Weight / Q000592:standards*; D006801:Humans
D000925:Anticoagulants; D016568:Drugs, Generic; D006495:Heparin, Low-Molecular-Weight