title: Prior heavy exercise enhances performance during subsequent perimaximal exercise.
abstract: OBJECTIVE
  To test the hypothesis that prior heavy exercise increases the time to exhaustion during subsequent perimaximal exercise.
  
  
  METHODS
  Seven healthy males (mean +/- SD 27 +/- 3 yr; 78.4 +/- 0.7 kg) completed square-wave transitions from unloaded cycling to work rates equivalent to 100, 110, and 120% of the work rate at VO2peak (W-[VO2peak) after no prior exercise (control, C) and 10 min after a 6-min bout of heavy exercise at 50% Delta (HE; half-way between the gas exchange threshold (GET) and VO2peak), in a counterbalanced design.
  
  
  RESULTS
  Blood [lactate] was significantly elevated before the onset of the perimaximal exercise bouts after prior HE (approximately 2.5 vs approximately 1.1 mM; P < 0.05). Prior HE increased time to exhaustion at 100% (mean +/- SEM. C: 386 +/- 92 vs HE: 613 +/- 161 s), 110% (C: 218 +/- 26 vs HE: 284 +/- 47 s), and 120% (C: 139 +/- 18 vs HE: 180 +/- 29 s) of W-VO2peak, (all P < 0.01). VO2 was significantly higher at 1 min into exercise after prior HE at 110% W-VO2peak (C: 3.11 +/- 0.14 vs HE: 3.42 +/- 0.16 L x min(-1); P < 0.05), and at 1 min into exercise (C: 3.25 +/- 0.12 vs HE: 3.67 +/- 0.15; P < 0.01) and at exhaustion (C: 3.60 +/- 0.08 vs HE: 3.95 +/- 0.12 L x min(-1); P < 0.01) at 120% of W-VO2peak.
  
  
  CONCLUSIONS
  This study demonstrate that prior HE, which caused a significant elevation of blood [lactate], resulted in an increased time to exhaustion during subsequent perimaximal exercise presumably by enabling a greater aerobic contribution to the energy requirement of exercise.
authors.affiliation: Department of Exercise and Sport Science, Manchester Metropolitan University, Alsager, United Kingdom. a.m.jones@mmu.ac.uk
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Jones
authors.forename: Daryl P
authors.initials: DP
authors.lastname: Wilkerson
authors.forename: Mark
authors.initials: M
authors.lastname: Burnley
authors.forename: Katrien
authors.initials: K
authors.lastname: Koppo
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology*; D005221:Fatigue; D006339:Heart Rate; D006801:Humans; D007700:Kinetics; D019344:Lactic Acid / Q000097:blood; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D011659:Pulmonary Gas Exchange / Q000502:physiology*
chemical_list: D019344:Lactic Acid