title: Optimizing flexion after total knee arthroplasty: advances in prosthetic design.
abstract: The clinical results with most modern total knee arthroplasty (TKA) designs are highly satisfactory regarding pain relief and improving walking ability. However, one problem that has not been addressed fully by most current designs is the ability to consistently achieve flexion greater than 120 degrees. Although the human knee is capable of flexion of more than 150 degrees, an analysis of the results of contemporary TKA reveals that on average, patients rarely flex beyond 120 degrees. Key factors influencing range of flexion after TKA include preoperative knee motion, surgical technique, prosthetic design, and rehabilitation. The success of any total knee system may in part be linked to its ability to optimally restore normal kinematic function. Some arthroplasty designs currently are available that incorporate modifications aimed at improving range of flexion, but limited data currently are available on their function and potential advantages. Currently, an in vitro experimental model incorporating robotics is being used to investigate the kinematics of the native knee and various TKA designs at flexion angles beyond 120 degrees. This robotic model in conjunction with clinical studies may provide an understanding of the limitations of contemporary knee designs regarding achieving higher degrees of knee flexion. This may lead to the refinement of existing designs and development of newer prostheses that may enhance the range of flexion that is achievable after TKA.
authors.affiliation: Harvard Medical School, MGH/BIDMC Boston, MA 02114, USA.
authors.forename: Peter G
authors.initials: PG
authors.lastname: Sultan
authors.forename: Ephrat
authors.initials: E
authors.lastname: Most
authors.forename: Steven
authors.initials: S
authors.lastname: Schule
authors.forename: Guoan
authors.initials: G
authors.lastname: Li
authors.forename: Harry E
authors.initials: HE
authors.lastname: Rubash
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D006801:Humans; D007719:Knee Joint / Q000502:physiology / Q000503:physiopathology; D007720:Knee Prosthesis / Q000639:trends*; D011474:Prosthesis Design; D016059:Range of Motion, Articular / Q000502:physiology*