Design of a new and highly effective chiral auxiliary for Diels-Alder reaction of 1-aminodiene.
A theoretical investigation of the facial selectivity of optically active oxazolidin-2-one-substituted dienes has been realized. This analysis enabled the development of (R)-4-phenyloxazolidin-2-thione as a very effective chiral auxiliary for cycloaddition of 1-aminodiene.
Robiette
Raphaël
R
Unité de Chimie organique et médicinale, Université catholique de Louvain, Place L. Pasteur 1, B-1348 Louvain-la-Neuve, Belgium.
Cheboub-Benchaba
Karima
K
Peeters
Daniel
D
Marchand-Brynaert
Jaqueline
J