Modeling ion channel regulation.
Remarkable recent successes in structure determinations of voltage-gated channels, ligand-gated channels, mechanosensitive channels and proton channels have advanced our understanding of the molecular basis of ion channel gating substantially. Models have helped to clarify aspects of this process and are now being designed as sophisticated biomimetics for various technological applications.
Woolley
G Andrew
GA
Department of Chemistry, University of Toronto, 80 St George Street, Toronto, ON, M5S 3H6, Canada. awoolley@chem.utoronto.ca
Lougheed
Tyler
T
D006863:Hydrogen-Ion Concentration; D015640:Ion Channel Gating / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008024:Ligands; D008958:Models, Molecular; D011522:Protons
D007473:Ion Channels; D008024:Ligands; D011522:Protons