title: [Acute diffuse thrombosis of left coronary artery complicating coronary angioplasty].
abstract: The paper presents a case report for successful treatment of acute diffuse thrombosis developed in left coronary artery after coronary angioplasty fulfilled for 39-year-old patient with acute coronary syndrome. Heparin resistance accompanied by intracoronary intervention triggered severe ascending thrombosis of the whole anterior descending artery with involvement of circumflex artery ostium. Therapeutic measures included: repeated Heparin bolus injection (total 27,000 U), bolus intracoronary Streptokinase injection (500,000 U) with subsequent Streptokinase infusion (1,000,000 U in 1 hour), stenting of circumflex artery ostium for thrombus mechanical destruction. This enabled us to restore adequate coronary flow and to resolve critical condition with minimal loss (periprocedural complication - repeated non-Q wave myocardial interfaction).
authors.affiliation: Methods for Cardiovascular Treatment, Novosibirsk Regional Cardiological Health Center, Novosibirsk, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Ganiukov
authors.forename: N I
authors.initials: NI
authors.lastname: Susoev
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Bravve
authors.forename: A A
authors.initials: AA
authors.lastname: Shilov
authors.forename: I N
authors.initials: IN
authors.lastname: Shigantsov
authors.forename: E A
authors.initials: EA
authors.lastname: Levchenko
authors.forename: M V
authors.initials: MV
authors.lastname: Demina
mesh_terms: D000208:Acute Disease; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D000925:Anticoagulants / Q000627:therapeutic use; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D004562:Electrocardiography; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*; D011183:Postoperative Complications
chemical_list: D000925:Anticoagulants; D006493:Heparin