title: Laser epithelial keratomileusis for myopia.
abstract: OBJECTIVE
  To describe a new technique for excimer laser corneal surgery: laser epithelial keratomileusis (LASEK).
  
  
  METHODS
  We report 76 eyes with spherical equivalent refractive myopia ranging from -8.00 to -22.00 D (mean -11.00 +/- 3.00 D). Using ethanol applied over an 8.5-mm-diameter area for 20 seconds, the epithelium was detached and photorefractive keratectomy (PRK) was performed. The epithelium was reapplied to the ocular surface and covered with a therapeutic soft contact lens. Treatments were carried out with the Nidek EC-5000 excimer laser.
  
  
  RESULTS
  At a mean of 803 days after LASEK, mean spherical equivalent refraction was -1.80 +/- 2.40 D (range -9.27 to +2.00 D). Stability was reached in approximately 60 days. Fifty-nine percent of the epithelial flaps were easy to detach intact during surgery and 62.7% of patients reported no postoperative pain. Eighty-four percent of eyes had the therapeutic bandage lens removed by the fourth postoperative day. Twelve percent of eyes had incomplete epithelial flap removal. Epithelium can fall off the cornea during the healing phase. No significant subepithelial haze was seen in 95% of eyes.
  
  
  CONCLUSIONS
  With LASEK, it may be possible to treat a larger diameter ablation zone in thinner corneas without the problems of a LASIK stromal flap and with less postoperative pain than PRK, with minimal subepithelial haze.
authors.affiliation: Sekal Microchirurgia Rovigo, Rovigo, Italy. cammas@tin.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Camellin
mesh_terms: D000328:Adult; D019573:Epithelium, Corneal / Q000502:physiology / Q000601:surgery*; D005260:Female; D006801:Humans; D054018:Lasers, Excimer; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D010149:Postoperative Pain; D018903:Photorefractive Keratectomy / Q000379:methods*; D012029:Refraction, Ocular / Q000502:physiology; D012449:Safety; D013524:Surgical Flaps; D014792:Visual Acuity / Q000502:physiology; D014945:Wound Healing