Toward an understanding of the structural basis of translation.
The recently solved X-ray crystal structures of the ribosome have provided opportunities for studying the molecular basis of translation with a variety of methods including cryo-electron microscopy - where maps give the first glimpses of ribosomal evolution - and fluorescence spectroscopy techniques.
Frank
Joachim
J
Howard Hughes Medical Institute, Health Research, Inc, at the Wadsworth Center and Department of Biomedical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA. Joachim@wadsworth.org
D000818:Animals; D020285:Cryoelectron Microscopy; D006801:Humans; D010445:Peptide Elongation Factors / Q000235:genetics / Q000378:metabolism; D014176:Protein Biosynthesis; D012335:RNA, Ribosomal / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure*
D010445:Peptide Elongation Factors; D012335:RNA, Ribosomal