title: Beneficial effect of goat milk on bioavailability of copper, zinc and selenium in rats.
abstract: We studied the effects of dietary inclusion of freeze-dried goat and cow milk on the utilization of copper, zinc and selenium, and on the metabolic fate of copper and zinc, in rats using a standard (non-milk) control diet recommended by the American Institute of Nutrition and diets based on goat or cow milk. For animals given the goat milk diet, the apparent digestibility coefficient (ADC) of copper is similar to that obtained with the standard diet and higher than that in animals given the cow milk diet. The copper balance was higher among the rats given the goat milk and the standard diets than among those given cow milk. The ADC and retention of zinc and selenium were higher for the goat milk diet than for the other two diets. The copper content in the kidneys and in the femur was greater when the animals consumed a goat milk diet than a cow milk diet. Zn deposits in femur, testes, liver, kidney, heart and longissimus dorsi muscle were greatest with the goat-milk diet, followed by the standard diet and were lowest for the rats given cow-milk diet. This study shows that the goat-milk has an important and beneficial effect on the bioavailability of copper, zinc and selenium.
authors.affiliation: Department of Physiology, Institute of Nutrition and Food Technology, University of Granada, 18071 Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Barrionuevo
authors.forename: I
authors.initials: I
authors.lastname: López Aliaga
authors.forename: M J M
authors.initials: MJ
authors.lastname: Alférez
authors.forename: E
authors.initials: E
authors.lastname: Mesa
authors.forename: T
authors.initials: T
authors.lastname: Nestáres
authors.forename: M S
authors.initials: MS
authors.lastname: Campos
mesh_terms: D000818:Animals; D002417:Cattle; D003300:Copper / Q000493:pharmacokinetics; D004063:Digestion; D006041:Goats; D008297:Male; D008892:Milk / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012643:Selenium / Q000493:pharmacokinetics; D014018:Tissue Distribution; D014131:Trace Elements / Q000493:pharmacokinetics*; D015032:Zinc / Q000493:pharmacokinetics
chemical_list: D014131:Trace Elements; D003300:Copper; D012643:Selenium; D015032:Zinc