title: Association between folic acid food fortification and congenital orofacial clefts.
abstract: By January 1998, most of Canada's cereal grain products were being fortified with folic acid. Among 336963 women who underwent antenatal maternal serum screening, the prevalence of orofacial clefts did not change from before (1.15 per 1000) to after (1.21 per 1000) food fortification (prevalence ratio, 1.06; 95% confidence interval, 0.86-1.30).
authors.affiliation: Department of Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada. jray515445@aol.com
authors.forename: Joel G
authors.initials: JG
authors.lastname: Ray
authors.forename: Chris
authors.initials: C
authors.lastname: Meier
authors.forename: Marian J
authors.initials: MJ
authors.lastname: Vermeulen
authors.forename: Philip R
authors.initials: PR
authors.lastname: Wyatt
authors.forename: David E c
authors.initials: DE
authors.lastname: Cole
mesh_terms: D002170:Canada / Q000453:epidemiology; D002971:Cleft Lip / Q000453:epidemiology / Q000517:prevention & control*; D002972:Cleft Palate / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D005527:Food, Fortified; D006397:Hematinics / Q000008:administration & dosage*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D015397:Program Evaluation; D012189:Retrospective Studies
chemical_list: D006397:Hematinics; D005492:Folic Acid