Biosensors for environmental monitoring of endocrine disruptors: a review article.
This article provides an overview of the applications of biosensors in analysis and monitoring of endocrine-disrupting compounds (EDCs) in the environment. Special attention is devoted to the various types of physical-chemical signal transduction elements, biological mechanisms employed as sensing elements and techniques used for immobilisation of the bioreceptor molecules on the transducer surface. Two different classes of biosensors for EDCs are considered: biosensors that measure endocrine-disrupting effects, and biosensors that respond to the presence of a specific substance (or group of substances) based on the specific recognition of a biomolecule. Several examples of them are presented to illustrate the power of the biosensor technology for environmental applications. Future trends in the development of new, more advanced devices are also outlined.
Rodriguez-Mozaz
Sara
S
Department of Environmental Chemistry, IIQAB-CSIC, C/ Jordi Girona 18-26, 08034 Barcelona, Spain.
Marco
Maria-Pilar
MP
Lopez de Alda
Maria J
MJ
Barceló
Damià
D
D015374:Biosensing Techniques; D004702:Endocrine Glands / Q000187:drug effects*; D004784:Environmental Monitoring; D004968:Estrogens, Non-Steroidal / Q000032:analysis / Q000633:toxicity; D006801:Humans
D004968:Estrogens, Non-Steroidal