Anti-streptolysin O titers in normal healthy children of 5-15 years.
Antistreptolysin O (ASO) levels vary with age group of the study population and geographical locations. The present study was undertaken to determine the upper limit of normal of ASO in 200 normal children of 5-15 years of age with no history of recent sore throat infection. The standard tube dilution method (WHO) was used for estimating ASO titers. It was found that 239 IU was the upper limit of normal in the study population, which can be considered as the baseline ASO titer. This can provide useful guidelines for physicians in the interpretation of elevated ASO titers in cases of suspected acute rheumatic fever.
Sethi
Sunit
S
Departments of Medical Microbiology and Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India. sunilsethi10@hotmail.com
Kaushik
Kirti
K
Mohandas
Kavya
K
Sengupta
Caesar
C
Singh
Surjit
S
Sharma
Meera
M
D000293:Adolescent; D000367:Age Factors; D000989:Antistreptolysin / Q000097:blood / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D012016:Reference Values; D012213:Rheumatic Fever / Q000175:diagnosis*; D018570:Risk Assessment; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D013297:Streptococcus pyogenes / Q000276:immunology*
D000989:Antistreptolysin