Ductal lavage in the screening of high-risk women.
Due to the high incidence of breast cancer and the excessively high false-positive rate of current screening technologies, adjunctive risk assessment measures are needed. Nipple aspiration cytologic analysis and random fine-needle aspirations have been proposed; however, ductal lavage and cytologic analysis of the effluent is a more sensitive and specific test. The dilemma lies in what should be done subsequent to a ductal lavage yielding malignant or atypical cells. The procedures and potential management strategies are discussed.
Kenney
Patrick J
PJ
Women's Cancer Center Los Angeles, Queen of Angels-Hollywood Presbyterian Medical Center, 1300 North Vermont Avenue, Los Angeles, CA 90027, USA.
Ellison
Margarett C
MC
D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D003581:Cytodiagnosis / Q000639:trends; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000639:trends; D012307:Risk Factors; D007507:Therapeutic Irrigation / Q000639:trends; D014481:United States / Q000453:epidemiology; D016387:Women's Health