title: The protective effects of a new preparation on wound edges.
abstract: OBJECTIVE
  This study investigated the effect of Cavilon No Sting Barrier Film (NSBF) (3M Healthcare) on erythema on the edges of highly exuding wounds in patients with venous stasis ulcers.
  
  
  METHODS
  An intra-individual double-blind randomised test was performed on 239 patients. The two sides of each wound on each patient were treated with two different dressings: Cavilon NSBF was applied to the wound edges of one side and a control (water) to the edges of the other. Erythema was assessed daily using a chromameter.
  
  
  RESULTS
  These are based on the 227 patients who completed the study. The researchers were surprised by their unambiguity: in 88.1% of patients, the erythema completely disappeared within three days of treatment with the test material; in the remaining 11.9% it had completely disappeared after four days. With the control, erythema intensity remained more or less unchanged throughout the four-day observation period.
  
  
  CONCLUSIONS
  This study demonstrates that Cavilon NSBF helped control erythema in all the patients: in 97.3% examined, the measurable and objectively recordable erythema receded within two days.
authors.affiliation: German Research and Consulting Centre for Nursing Products, Göttingen, Germany.
authors.forename: K-D
authors.initials: KD
authors.lastname: Neander
authors.forename: F
authors.initials: F
authors.lastname: Hesse
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D001458:Bandages; D004311:Double-Blind Method; D004890:Erythema / Q000209:etiology / Q000517:prevention & control*; D005122:Exudates and Transudates; D006801:Humans; D012867:Skin / Q000378:metabolism; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000150:complications / Q000451:nursing; D014867:Water / Q000378:metabolism; D014947:Wounds and Injuries / Q000150:complications* / Q000378:metabolism / Q000451:nursing*
chemical_list: D014867:Water