title: Dendritic cells in cancer immunotherapy - a short review.
abstract: Dendritic cells (DCs) are rare leukocytes that are uniquely potent in their recent application to therapeutic cancer vaccines. Isolated DCs loaded with tumour antigen ex vivo and administered as a cellular vaccine have been found to induce protective and therapeutic anti-tumour immunity. In the present report we describe the most common methods of culturing DCs and delivering tumour antigens and we summarise clinical trials of cancer immunotherapy using DCs-based vaccines.
authors.affiliation: Department of Clinical Immunology, Medical University, Lublin, Poland. kamilawojas@poczta@onet.pl
authors.forename: Kamila
authors.initials: K
authors.lastname: Wojas
authors.forename: Jacek
authors.initials: J
authors.lastname: Tabarkiewicz
authors.forename: Jacek
authors.initials: J
authors.lastname: Roliński
mesh_terms: D000951:Antigens, Neoplasm / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*
chemical_list: D000951:Antigens, Neoplasm