[Two cases of systemic amyloidosis presenting with abnormalities in liver function tests].
Systemic amyloidosis results from the deposition of insoluble, fibrous amyloid proteins. It occurs mainly in the extracellular spaces of multiple organs and tissues including the kidney, heart, and liver. Although amyloid deposition in the liver is common in patients with systemic amyloidosis, clinically apparent liver disease is relatively rare. Indeed, most patients with systemic amyloidosis manifest only minimal to moderate hepatomegaly and trivial abnormalities in liver function tests. Recently, we experienced two cases of patients who presented with abnormalities in liver function tests and hepatomegaly as manifestations of systemic amyloidosis. We report these cases with a review of the relevant literatures.
Park
Jin Hyung
JH
Department of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea.
Park
Chang Kun
CK
Yun
Young Mi
YM
Hyun
Dong Woo
DW
Kim
Eun Soo
ES
Park
Soo Young
SY
Jo
Chang Min
CM
Tak
Won Young
WY
Kweon
Young Oh
YO
Kim
Sung Kook
SK
Choi
Yong Whan
YW
D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000473:pathology*; D005260:Female; D006529:Hepatomegaly / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged