title: Diabetic mastopathy in an advanced elderly woman with insulin-dependent type 2 diabetes mellitus.
abstract: Diabetic mastopathy is an unusual stromal fibrotic lesion, but typically occurs in long-standing insulin dependent and younger diabetic patients. We report a case of diabetic mastopathy in an older diabetic patient. The patient was a 76-year-old woman with a history of type 2 diabetes mellitus for 13 years and 3 years of insulin treatment. She developed a 3 cm, hard, mobile nodule in the left breast. Mammography revealed a dense mass. Ultrasonography showed an irregular-shaped hypoechoic lesion with an unclear boundary and acoustic shadowing. Since fine needle aspiration biopsy delivered insufficient material and core needle biopsy did not yield any specific findings for diagnosis, clinically diabetic mastopathy was the prime suspect but breast cancer could be completely ruled out. Surgical excision was thus performed and diabetic mastopathy was confirmed pathologically. We report on this rare case of diabetic mastopathy in a 76 year-old type 2 diabetic patient.
authors.affiliation: Department of Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. kojimat-sur@h.u-tokyo.ac.jp
authors.forename: Tetsu
authors.initials: T
authors.lastname: Kojima
authors.forename: Makoto
authors.initials: M
authors.lastname: Kammori
authors.forename: Masanori
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Ogawa
authors.forename: Hidemitsu
authors.initials: H
authors.lastname: Yasuda
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takazawa
authors.forename: Kaiyo
authors.initials: K
authors.lastname: Takubo
authors.forename: Michio
authors.initials: M
authors.lastname: Kaminishi
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D006801:Humans; D008327:Mammography; D017698:Postmenopause; D014057:Tomography, X-Ray Computed; D016217:Ultrasonography, Mammary