Construction of VNP20009: a novel, genetically stable antibiotic-sensitive strain of tumor-targeting Salmonella for parenteral administration in humans.
Low
Kenneth Brooks
KB
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Ittensohn
Martina
M
Luo
Xiang
X
Zheng
Li-Mou
LM
King
Ivan
I
Pawelek
John M
JM
Bermudes
David
D
D000818:Animals; D001428:Bacterial Vaccines; D041722:Genes, Transgenic, Suicide / Q000235:genetics*; D005818:Genetic Engineering; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008546:Melanoma, Experimental / Q000276:immunology* / Q000628:therapy; D051379:Mice; D008810:Mice, Inbred C57BL; D008819:Mice, Nude; D012475:Salmonella / Q000235:genetics* / Q000276:immunology; D014018:Tissue Distribution; D014161:Transduction, Genetic / Q000379:methods*; D014613:Vaccines, Attenuated / Q000493:pharmacokinetics / Q000627:therapeutic use*
D001428:Bacterial Vaccines; C465023:VNP 20009; D014613:Vaccines, Attenuated