[Clinical study on effect of yuantong capsule in treating vascular dementia].
OBJECTIVE
To observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD).


METHODS
Eighty-three patients of VD were randomized on ratio of 2:1 into two groups, the 54 patients in the treated group were treated with YTC orally administered, 3 times a day, 1 capsule in each time. The remaining 29 patients in the control group were treated with Hydergine orally, 3 times a day, 2 mg in each time. The therapeutic course for both groups was 2 months.


RESULTS
The therapeutic effect in the treated group was significantly better than that in the control group, significant difference (P < 0.05 or P < 0.01) was shown in comparison of the two groups in terms of the mini-mental state examination (MMSE) and activity of daily living (ADL) test, symptoms scoring, total effective rate, and laboratory indexes findings.


CONCLUSIONS
The therapeutic effect of YTC in treating VD was obvious.
Huang
Jun-shan
JS
Affiliated Union Hospital of Fujian Medical University, Fuzhou 350001. hjsh0825@163.com
Lin
Qiu-cheng
QC
Huang
Rong-zhang
RZ
D000368:Aged; D000369:Aged, 80 and over; D002214:Capsules; D015140:Dementia, Vascular / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004877:Ergoloid Mesylates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018697:Nootropic Agents / Q000627:therapeutic use; D008517:Phytotherapy
D002214:Capsules; D004365:Drugs, Chinese Herbal; D018697:Nootropic Agents; D004877:Ergoloid Mesylates