[Molecular-genetic comparison of morbilliviruses which caused epizooty in Baikal (Phoca siberica) and Caspian (Phoca caspica) seals].
The nucleotide sequences were determined for a phosphoprotein gene fragment of canine distemper virus (CDV) by using the RT-PCR method with the subsequent sequencing of amplicons from total RNA isolated from 2 samples of Caspian seals, 15 samples of Baikal seals and from samples of dog's and sea-lion's brains. The above materials were phylogenetically analyzed. The heterogeneity of the virus circulating in the Baikal-seal population was demonstrated. Morbillivirus, that caused epizooty in Caspian seals, was shown to be a CDV variant, whose phosphoprotein gene structure was not different, within the analyzed stretch, from the corresponding gene of the most widespread variant of the Baikal seal virus. The data obtained suggest that morbillivirus could be transmitted by birds during their seasonal migrations.
Butina
T V
TV
Denikina
N N
NN
Kondratov
I G
IG
Belikov
S I
SI
Durymanova
A A
AA
Blinov
V M
VM
Shestopalov
A M
AM
D000820:Animal Diseases / Q000453:epidemiology / Q000821:virology; D000818:Animals; D001483:Base Sequence; D005814:Genes, Viral; D005821:Genetic Techniques; D014644:Genetic Variation; D008969:Molecular Sequence Data; D018103:Morbillivirus / Q000235:genetics*; D018185:Morbillivirus Infections / Q000453:epidemiology / Q000821:virology; D010750:Phosphoproteins / Q000235:genetics; D010802:Phylogeny; D046048:Seals, Earless / Q000821:virology*; D012800:Siberia
D010750:Phosphoproteins