title: [Acute colonic pseudo-obstruction (Ogilvie's syndrome) in pneumococcal meningo-encephalitis treated with neostigmine].
abstract: We report the case of a 71-year-old man with acute colonic pseudo-obstruction that complicates a pneumococcal meningo-encephalitis. After 48 h of conservative management with nothing by mouth, nasogastric suction, fluid and electrolyte correction, withdrawal of any anticholinergic agents, a pharmacological approach with 2 mg of neostigmine was successful in intensive care unit. This treatment was effective in over 80% of patients of recent reports. Neostigmine might be considered as first-line therapy in patients who do not have major contraindications to its use, because of less frequent iatrogenic risk than colonoscopic decompression or surgery.
authors.affiliation: Service de réanimation médicale, centre hospitalier universitaire Cavale-Blanche, 29609 Brest, France. mehdi.oa@wanadoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Ould-Ahmed
authors.forename: L
authors.initials: L
authors.lastname: de Saint-Martin
authors.forename: S
authors.initials: S
authors.lastname: Ansart
authors.forename: A
authors.initials: A
authors.lastname: Renault
authors.forename: J-M
authors.initials: JM
authors.lastname: Boles
mesh_terms: D000368:Aged; D003112:Colonic Pseudo-Obstruction / Q000000981:diagnostic imaging / Q000209:etiology*; D003422:Critical Care; D006801:Humans; D008297:Male; D008586:Meningitis, Pneumococcal / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D008590:Meningoencephalitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D009388:Neostigmine / Q000627:therapeutic use*; D011859:Radiography
chemical_list: D009388:Neostigmine