title: Outcome of zone 1 retinopathy of prematurity.
abstract: OBJECTIVE
  To describe the outcome in a series of patients with pre-threshold and threshold zone 1 retinopathy of prematurity.
  
  
  METHODS
  We performed a retrospective analysis of 12 babies, 24 eyes, with zone 1 retinopathy of prematurity, treated between 1992 and 2002 with diode laser treatment.
  
  
  RESULTS
  Ten out of the 12 babies had an unfavourable outcome. The only patients with successful anatomical outcomes were those treated before threshold disease occurred. All babies had developmental delay or neurological disability.
  
  
  CONCLUSIONS
  Zone 1 retinopathy of prematurity has a poor anatomical and visual prognosis and many of the babies in our study had developmental delay and neurological disability. Earlier treatment may improve the visual outcome.
authors.affiliation: National Children's Eye Centre, Children's University Hospital, Temple Street, Dublin 1, Ireland. tchopth@indigo.ie
authors.forename: Michael
authors.initials: M
authors.lastname: O'Keefe
authors.forename: Bernadette
authors.initials: B
authors.lastname: Lanigan
authors.forename: Vernon W
authors.initials: VW
authors.lastname: Long
mesh_terms: D017679:Cryotherapy; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017075:Laser Coagulation / Q000379:methods*; D008297:Male; D011379:Prognosis; D015861:Retinal Neovascularization / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012178:Retinopathy of Prematurity / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D012591:Scleral Buckling; D014792:Visual Acuity / Q000502:physiology