Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies.
Analysis of FcgammaRIIA alleles in Pakistanis and in Trinidadians of South Asian, African and mixed ancestry revealed no significant differences between Trinidadian South Asians and Pakistanis. H131 homozygotes were more common among Trinidadian South Asians than among Africans and those of mixed ancestry. Comparison with other populations revealed east-west geographic gradients of allele frequencies.
Carrington
C V F
CV
University of the West Indies, St. Augustine, Trinidad. ccarrington@fms.uwi.tt
Norman
P J
PJ
Vaughan
R W
RW
Kondeatis
E
E
Ramdath
D D
DD
Hameed
K
K
Stephens
H A F
HA
D000349:Africa; D015703:Antigens, CD / Q000235:genetics*; D001208:Asia; D005787:Gene Frequency; D006801:Humans; D011110:Polymorphism, Genetic; D017452:Receptors, IgG / Q000235:genetics*
D015703:Antigens, CD; C080568:Fc gamma receptor IIA; C080571:Fc gamma receptor IIB; C080572:Fc gamma receptor IIC; D017452:Receptors, IgG