title: [Characteristics of bacteriology and drug sensitivity in patients with COPD combined with pneumonia].
abstract: OBJECTIVE
  To investigate the characteristics of bacteriology and the drug resistance in the patients with chronic obstructive disease (COPD) combined with pneumonia at our respiratory intensive care unit(RICU) in 2001.
  
  
  METHODS
  The sputum of 543 patients with COPD combined with pneumonia was collected with a regular method, the bacteria were cultured, and then the drug sensitivity was analyzed with K-B method.
  
  
  RESULTS
  There were 181 positive samples in the 543 patients with the positive rate 33.9%. The main bacteria in the G- bacillus were Pseudomonas (21.55%), Haemophilus influenza (14.36%), Enteric bacilli (13.26%), and Klebsiella (11.60%) which were sensitive to impipenem, amikacin, and ceftazidime. The main bacteria in G+ bacteria were Staphylococcus aureus (7.18%) and Staphylococcus epidermindis (4.42%) which were sensitive to vancomycin, imipenem, ceftazidime, and amikacin.
  
  
  CONCLUSIONS
  The bacteria in the patients with COPD combined with pneumonia at RICU of the hospital in 2001 are mainly made up of G- bacillus and secondarily of G+ bacteria which are sensitive to imipenem, amikacin, and ceftazidime. The G+ bacteria are highly sensitive to vancomycin.
authors.affiliation: Department of Respiration, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Zhi-ming
authors.initials: ZM
authors.lastname: Yi
authors.forename: Hua
authors.initials: H
authors.lastname: Yang
authors.forename: Xu-dong
authors.initials: XD
authors.lastname: Xiang
mesh_terms: D000328:Adult; D000368:Aged; D000583:Amikacin / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005260:Female; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011014:Pneumonia / Q000382:microbiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000382:microbiology*; D014640:Vancomycin / Q000494:pharmacology
chemical_list: D014640:Vancomycin; D015378:Imipenem; D000583:Amikacin