[Clinical observation of recombinant growth hormone therapy for liver cirrhosis with hypoproteinemia].
OBJECTIVE
To assess the effect of recombinant growth hormone (rhGH) therapy for liver cirrhosis patients with hypoproteinemia.


METHODS
Fifteen patients with liver cirrhosis were treated with rhGH (4 U per day) for 7 days and 15 controls were given human albumin (10 g) for every other day (altogether 3 times). Albumin was measured one day before the treatment, and on day 1, 10, 14, and 28 after the treatment.


RESULTS
After 7 days of rhGH administration, the albumin level of the patients was significantly higher and the function lasted longer than those of patients treated with human albumin (P < 0.05).


CONCLUSIONS
Exogenous rhGH in treating hypoproteinemia in patients with liver cirrhosis is more effective than human albumin.
Liu
Shao-jun
SJ
Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Tang
Wu-liang
WL
Shen
Shou-rong
SR
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D034141:Hypoalbuminemia / Q000188:drug therapy* / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D013006:Growth Hormone