A probabilistic model for the extraction of expression levels from oligonucleotide arrays.
In this work we present a probabilistic model to estimate summaries of Affymetrix GeneChip probe level data. Comparisons with two different models were made both on a publicly available dataset and on a study performed in our laboratory, showing that our model performs better for consistency of fold change.
Milo
M
M
Department of Computer Science, University of Sheffield, 211 Portobello Street, Regent Court, Sheffield S4 1DP, U.K. m.milo@sheffield.ac.uk
Fazeli
A
A
Niranjan
M
M
Lawrence
N D
ND
D008962:Models, Theoretical; D020411:Oligonucleotide Array Sequence Analysis; D011336:Probability; D012680:Sensitivity and Specificity