title: Study of total lipid peroxidation and antioxidant activity in pulmonary and mediastinal malignant and benign tumor tissue.
abstract: Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of malignancy: the most pronounced changes were observed in thymoma and adenocarcinoma tissues and minimum changes were found in bronchoalveolar carcinoma tissue.
authors.affiliation: Clinical Biochemical Laboratory and Department of Thoracal Surgery, A. V. Vishnevskii Institute of Surgery, Russian Academy of Sciences, Moscow.
authors.forename: R N
authors.initials: RN
authors.lastname: Korotkina
authors.forename: O V
authors.initials: OV
authors.lastname: Spiridonova
authors.forename: G N
authors.initials: GN
authors.lastname: Matskevich
authors.forename: A Sh
authors.initials: ASh
authors.lastname: Kucheinik
authors.forename: A G
authors.initials: AG
authors.lastname: Kunitsyn
authors.forename: A A
authors.initials: AA
authors.lastname: Vishnevskii
authors.forename: A A
authors.initials: AA
authors.lastname: Karelin
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology*; D001984:Bronchial Neoplasms / Q000473:pathology; D045744:Cell Line, Tumor; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology; D013945:Thymoma / Q000473:pathology
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; D005979:Glutathione Peroxidase