title: Scanning laser Doppler flowmeter study of retinal blood flow in macular area of healthy volunteers.
abstract: OBJECTIVE
  To compare the interocular and intraocular differences of capillary perfusion, and the intraocular regional differences of retinal blood flow in the macular area of healthy volunteers.
  
  
  METHODS
  Tissue blood flow in the macula was examined in both eyes of 20 healthy volunteers with the Heidelberg retinal flowmeter. Blood flow measurements were made in a 10 degrees x 2.5 degrees area superior and inferior to the macula. The mean blood flow (MBF) was calculated by an automatic full field perfusion image analyser program. The MBF in the right and left eyes and in the superior and inferior macular areas of the same eye were compared.
  
  
  RESULTS
  The ratios of the MBF in the right eye to the left eye in the macular areas were 1.00, and 1.03, respectively. The ratio of the MBF in the superior macular area to the inferior area was 1.01 for the right eyes and 1.04 for the left eyes.
  
  
  CONCLUSIONS
  Because no significant differences were found in the MBF between the two eyes and between the superior and inferior macular areas in the same eye, interocular (for example, affected eye versus fellow eye) and intraocular (superior versus inferior macular areas) comparisons of MBF can be made to determine if changes in retinal perfusion have occurred.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. kimura@sc.itc.keio.ac.jp
authors.forename: I
authors.initials: I
authors.lastname: Kimura
authors.forename: K
authors.initials: K
authors.lastname: Shinoda
authors.forename: T
authors.initials: T
authors.lastname: Tanino
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtake
authors.forename: Y
authors.initials: Y
authors.lastname: Mashima
authors.forename: Y
authors.initials: Y
authors.lastname: Oguchi
mesh_terms: D000293:Adolescent; D000328:Adult; D002196:Capillaries; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D017078:Laser-Doppler Flowmetry; D008266:Macula Lutea / Q000098:blood supply*; D008297:Male; D010477:Perfusion; D012039:Regional Blood Flow; D015203:Reproducibility of Results; D012171:Retinal Vessels / Q000502:physiology