title: [Analyses of recurrences and nodal metastases of glottic carcinoma after operation].
abstract: OBJECTIVE
  To study the feature and prevention of local recurrences and nodal metastases of glottic carcinoma after operation.
  
  
  METHODS
  Seventy-six patients with glottic carcinoma were reviewed retrospectively. The relationship among the region involved by cancer, local recurrences, tumor stage and neck dissection was compared with multiple-factors stepwise regression. The relationship between the region involved by cancer and local recurrences was compared with chi-square test.
  
  
  RESULTS
  In this group of 76 patients with glottic carcinoma had been followed-up for 3 years, the 1-year and 3-year survival rate were 97.4% and 92.1%. Eleven had occurred local recurrences and/or cervical lymph node metastases after operation. Six of thirty-five patients (17.1%) whose anterior commissure was involved had recurrences during the follow-up period. There were no local recurrences in another 41 patients. Three of twelve patients whose glottic tumors with subglottic extension (extension more than 5 mm below the glottiis) were found paratracheal lymph node (PTLN) metastases, one of which was lower jugular lymph node metastases. The glottic tumors with supraglottic extension or glottic tumors with subglottic extension which invaded less than 5 mm weren't found PTLN metastases. By analysis of stepwise regression, it was found if there were the metastases of PTLN and lower jugular lymph node, the tumor often extend to the subglottic (P < 0.05). There is no difference between local recurrences and the tumor with or without involved anterior commissure (P > 0.05).
  
  
  CONCLUSIONS
  The glottic cancers with subglottic extension may occur PTLN and lower jugular lymph node metastases. The glottic cancers with involved anterior commissure are considered to be more at risk for local recurrences.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, First Hospital of Peking University, Beijing 100034.
authors.forename: Quangui
authors.initials: Q
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D011184:Postoperative Period; D012044:Regression Analysis; D012189:Retrospective Studies