title: Left-colon antegrade continence enema (LACE) procedure for fecal incontinence.
abstract: OBJECTIVE
  Antegrade continence enemas (ACE) are an efficacious therapeutic option for patients with fecal incontinence. The authors review their institution's experience with a variation of the Monti-Malone ACE procedure using the left colon as a source of an intestinal conduit and enema reservoir.
  
  
  METHODS
  From 2000 to 2002, 18 patients with fecal incontinence or intractable constipation underwent left-colon ACE (LACE) procedure. Concomitant Mitrofanoff appendicovesicostomy was performed in 15 patients and bladder augmentation in 9. The majority of patients had neural tube defects. A segment of left colon was tubularized, tunneled into the muscular wall of the distal colon, and exteriorized through the left upper quadrant or midabdomen. Stomal catherization and enema installation were started one month postoperatively.
  
  
  RESULTS
  Fifteen patients (83%) achieved fecal continence, 2 remain incontinent of stool, and 1 experienced stomal closure (mean follow-up was 24 +/- 9 months). Two patients had stomal stenosis that required revision. The mean enema volume in patient's achieving continence was 360 +/- 216 mL, and the mean transit time was 18 +/- 12 minutes.
  
  
  CONCLUSIONS
  LACE is an efficacious procedure for fecal incontinence that can be performed safely at the time of major urologic reconstruction. Administration of enemas into the left colon has several physiologic advantages that result in predictable bowel evacuation.
authors.affiliation: Department of Urology, Clark-Morrison Children's Urological Center, UCLA, Los Angeles, CA 90095-1738, USA.
authors.forename: Bernard M
authors.initials: BM
authors.lastname: Churchill
authors.forename: Daniel A
authors.initials: DA
authors.lastname: De Ugarte
authors.forename: James B
authors.initials: JB
authors.lastname: Atkinson
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003106:Colon / Q000601:surgery; D003248:Constipation / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods; D004733:Enema; D005242:Fecal Incontinence / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D054047:Surgical Stomas