Juvenile granulosa cell tumor of the testis: a case presenting as a small round cell tumor of childhood.
We describe the case of a testicular juvenile granulosa cell tumor (JGCT) in a 4-year-old boy. The highly undifferentiated appearance and robust mitotic activity of the neoplasm led to an initial impression of an aggressive, small round cell tumor of childhood. Immunocytochemical and ultrastructural studies excluded the usual members of that group, and led to the correct diagnosis. To our knowledge, this is the oldest reported patient to present with this tumor in the testis, and the first with clinical evidence of hormonal activity. The benign behavior of testicular JGCT mandates that it be distinguished from other, much more aggressive, neoplasms which it may resemble.
Fidda
Nisreen
N
Department of Pathology, Oregon Health and Science University, Portland, Oregon 97239, USA.
Weeks
Douglas A
DA
D018288:Carcinoma, Small Cell / Q000473:pathology* / Q000648:ultrastructure; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006106:Granulosa Cell Tumor / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D013736:Testicular Neoplasms / Q000473:pathology* / Q000648:ultrastructure