title: The initial stability of cemented acetabular cups can be augmented by mixing morsellized bone grafts with tricalciumphosphate/hydroxyapatite particles in bone impaction grafting.
abstract: Tricalciumphosphate (TCP) and hydroxyapatite (HA) have been suggested as bone graft substitutes in a wide range of applications. In this study, the initial stability of cemented acetabular cups was determined after reconstructing a combined cavitary and segmental defect in a realistic acetabular revision surgery model. The defects were reconstructed with mixes of TCP/HA particles and human bone grafts using the bone impaction grafting technique. In comparison with defect reconstruction with human bone grafts only, cup translation and tilt decreased by 27% when mixes of bone grafts and porous TCP/HA particles were used and by 55% when mixing the bone grafts with solid TCP/HA particles. Increasing the TCP/HA ratio within the mix significantly decreased cup translation. From a biomechanical perspective, mixes of TCP/HA particles and bone grafts are an attractive alternative for morsellized bone grafts when using the bone impaction grafting technique in the reconstruction of large defects of the acetabulum.
authors.affiliation: Orthopaedic Research Lab, University Medical Center Nijmegen, The Netherlands.
authors.forename: S B T
authors.initials: SB
authors.lastname: Bolder
authors.forename: N
authors.initials: N
authors.lastname: Verdonschot
authors.forename: B W
authors.initials: BW
authors.lastname: Schreurs
authors.forename: P
authors.initials: P
authors.lastname: Buma
mesh_terms: D000077:Acetabulum; D001696:Biomechanical Phenomena; D018786:Bone Substitutes; D002130:Calcium Phosphates; D002484:Cementation; D017886:Durapatite; D006622:Hip Prosthesis; D006801:Humans; D008422:Materials Testing; D012086:Reoperation
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate; D017886:Durapatite; C018392:tricalcium phosphate