title: [Dynamics of clinical symptoms, indices of quality of life, and the state of motor function of the esophagus and rectum in patients with functional dyspepsia and irritable bowel syndrome after Helicobacter pylori eradication].
abstract: 94 patients with irritable bowel syndrome and functional dyspepsia were included in the study. To confirm the diagnosis of H. pylori infection, all patients underwent fibroesophagogastroduodenoscopy with histological and urea tests before and 5 weeks after treatment. Standard eradication was performed. 25 patients underwent intraesophageal and anorectal manometry using the Polygraf device, Sweden. The dynamics of clinical symptoms, life quality (SF-36), manometry data and data of the histological examination of the stomach mucous coat was assessed. 63.5% of patients had clinical improvements following the eradication. The threshold of rectal sensitivity rose in 40% of patients. The esophageal motor function normalized in 48% of patients. An improvement of the morphological picture of chronic gastritis was recorded in 58.7% of patients.
authors.affiliation: State Medical University of the Far East, Road Clinical Hospital of the Khabarovsk-I Station, Khabarovsk.
authors.forename: S A
authors.initials: SA
authors.lastname: Alekseenko
authors.forename: O V
authors.initials: OV
authors.lastname: Krapivnaia
authors.forename: O K
authors.initials: OK
authors.lastname: Kamalova
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Vasiaev
authors.forename: A V
authors.initials: AV
authors.lastname: Pyrkh
mesh_terms: D000328:Adult; D004415:Dyspepsia / Q000382:microbiology / Q000503:physiopathology*; D004947:Esophagus / Q000502:physiology; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005769:Gastrointestinal Motility; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000382:microbiology / Q000503:physiopathology*; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011788:Quality of Life; D012007:Rectum / Q000502:physiology; D014510:Urease
chemical_list: D014510:Urease