[Assessment of changes in levels of interleukin 6 and C reactive protein in patients with breast tumors].
Serum concentrations of interleukin 6 (IL-6) and C-reactive protein (CRP) were determined in 74 patients with various histological types and clinical stages of breast carcinoma, recurrent breast carcinoma and of benign breast tumor. The concentrations of IL-6 and CRP were significantly increased in carcinoma patients relative to control group and to benign breast tumor group. The frequency of higher levels and absolute value of IL-6 and CRP showed tendency to significant increase with the stage of disease. A positive correlation was observed between the concentrations of IL-6 and CRP. Our results suggest that of IL-6 assay may be useful in estimation of progress disease in patients with breast carcinoma.
Zakrzewska
Irena
I
Zakład Laboratoryjnej Diagnostyki Klinicznej AM w Białymstoku.
Kozłowski
Leszek
L
Wojtukiewicz
Marek
M
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D001943:Breast Neoplasms / Q000276:immunology* / Q000378:metabolism*; D002097:C-Reactive Protein / Q000378:metabolism*; D002277:Carcinoma / Q000276:immunology* / Q000378:metabolism*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood* / Q000276:immunology*; D008875:Middle Aged
D015850:Interleukin-6; D002097:C-Reactive Protein