Recent applications of microemulsion electrokinetic chromatography.
Microemulsions are used in a similar way as micellar solutions are used for separations in capillary electrophoresis. Within the last approximately six years, a number of papers have appeared in the literature in which the separation characteristics of microemulsion electrokinetic chromatography (MEEKC) have been investigated. The total number of papers dealing with MEEKC is now close to 100. One of the major fields of application for MEEKC has been the characterization of the lipophilicity of chemical substances but the technique has also been applied for the analysis of substances within the fields of natural products, pharmaceuticals, vitamins, peptides, proteins, and nucleic acid bases as well as nucleosides. An overview of the applications is given together with the microemulsions used for each application.
Hansen
Steen Honoré
SH
The Danish University of Pharmaceutical Sciences, Department of Analytical Chemistry, Copenhagen, Denmark. shh@dfh.dk
D000470:Alkaloids / Q000032:analysis*; D001685:Biological Factors / Q000032:analysis*; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D004784:Environmental Monitoring; D004837:Epinephrine / Q000032:analysis*; D014815:Vitamins / Q000032:analysis*
D000470:Alkaloids; D001685:Biological Factors; D014815:Vitamins; D004837:Epinephrine