title: Determining a detectable threshold of signal intensity in cDNA microarray based on accumulated distribution.
abstract: In microarray data mining, one of the key problems is how to handle weak signals. Based on a bent piecewise linear accumulated distribution generally found in the microarray data, a new detectable threshold finding method is proposed to filter genes with unreliable information in this paper. More reliable and reproducible data is produced for the subsequent data mining.
authors.affiliation: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, PR China.
authors.forename: Xia
authors.initials: X
authors.lastname: Gao
authors.forename: Xuping
authors.initials: X
authors.lastname: Fu
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Zi
authors.forename: Yao
authors.initials: Y
authors.lastname: Luo
authors.forename: Qing
authors.initials: Q
authors.lastname: Wei
authors.forename: Erliang
authors.initials: E
authors.lastname: Zeng
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
authors.forename: Yao
authors.initials: Y
authors.lastname: Li
authors.forename: Yumin
authors.initials: Y
authors.lastname: Mao
mesh_terms: D018076:DNA, Complementary / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D015203:Reproducibility of Results
chemical_list: D018076:DNA, Complementary