Symptomatic hyponatremia in patients on oxcarbazepine therapy for the treatment of neuropathic pain: two case reports.
Oxcarbazepine is an FDA approved anticonvulsant medication that has also been used clinically as a treatment for chronic neuropathic pain. Hyponatremia is occasionally seen with the older anticonvulsant carbamazepine, and oxcarbazepine is a derivative of that older drug. Two cases of hyponatremia associated with oxcarbazepine are reported and suggestions for monitoring for and managing this effect are provided.
Adkoli
Sujnani
S
School of Medicine, Pain Management Center, Red Butte Health Center, University of Utah Hospitals and Clinics, Salt Lake City, UT 84108, USA. sadkoli@aol.com
D000328:Adult; D002220:Carbamazepine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology
C476610:oxcarbamazepine; D002220:Carbamazepine