title: Ocular myasthenia gravis associated with euthyroid ophthalmopathy.
abstract: We report a 71-year-old woman with concomitant ocular myasthenia gravis and euthyroid Graves' ophthalmopathy. Unilateral ophthalmoplegia, including ptosis, initially was responsive to edrophonium and corticosteroids, except for diplopia on upward gaze, but refractory swelling of the inferior rectus muscle and proptosis followed. Autoantibodies to acetylcholine and thyrotropin receptors were detected. Her ophthalmopathy abated after orbital irradiation in combination with systemic steroids. There may be an immunological basis for the association of ocular myasthenia gravis with euthyroid Graves' ophthalmopathy.
authors.affiliation: Department of Neurology, Fukuoka University School of Medicine, 7-45-1 Nanakuma Johnan-ku, Fukuoka 814-0180, Japan.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Kusuhara
authors.forename: Masashi
authors.initials: M
authors.lastname: Nakajima
authors.forename: Akiko
authors.initials: A
authors.lastname: Imamura
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005128:Eye Diseases / Q000150:complications* / Q000473:pathology; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D007116:Immunization, Passive; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D009157:Myasthenia Gravis / Q000150:complications* / Q000473:pathology; D014786:Vision Disorders / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone