title: A historical view of schistosomiasis japonica in the Chikugo river basin. What can we learn from autopsy?
abstract: Three hundred and forty-nine autopsy cases of schistosomiasis japonica were divided into two groups, based on the pathomorphology. Frequent regressive hepatic lesions such as active schistosomal lesion and destruction of limiting plates characterized the first group. The second group showed reparative hepatic lesions such as regeneration of the collapsed parenchyma, newly formed limiting plates and subsequent narrowing and disappearance of fibrous septa. Complications of liver cirrhosis and hepatocellular carcinoma related to viral hepatitis B and/or C also increased. Clonorchiasis was consistently found in both groups.
authors.affiliation: CRC, Inc, Kurume Laboratory, Kurume 839-0809, Japan.
authors.forename: Toshiro
authors.initials: T
authors.lastname: Nakashima
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kage
authors.forename: Mizuki
authors.initials: M
authors.lastname: Hirata
mesh_terms: D000818:Animals; D001344:Autopsy; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008099:Liver / Q000469:parasitology / Q000473:pathology; D012549:Schistosoma japonicum / Q000302:isolation & purification; D012554:Schistosomiasis japonica / Q000097:blood / Q000453:epidemiology / Q000473:pathology*