Sinonasal aspergillosis in immunocompetent Indian children: an eight-year experience.
A retrospective study of 40 otherwise healthy children suffering from paranasal aspergillosis is presented. Fifteen percentage of this group was under 10 years of age. The clinical characteristics were marked facial deformity, orbital involvement (52.5%) and skull base erosion (12.5%). Ethmoid sinus was the commonest sinus to be affected. Aspergillus serology was positive in 35% and fungal culture grew the organism in 40%. Histopathology revealed allergic or non-invasive fungal infections without any tissue invasions. Surgery was performed in all except one case. Recurrence was 15% treated by revision surgery and antifungal therapy.
Gupta
A K
AK
Department of Otolaryngology and Department of Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India. akgpgi@hotmail.com
Ghosh
S
S
Gupta
A K
AK
D000293:Adolescent; D000908:Antibodies, Fungal / Q000097:blood; D001228:Aspergillosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D001230:Aspergillus / Q000276:immunology / Q000302:isolation & purification; D002648:Child; D015521:Ethmoid Sinusitis / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D007121:Immunocompetence; D007194:India / Q000453:epidemiology; D008297:Male; D010254:Paranasal Sinus Diseases / Q000453:epidemiology / Q000382:microbiology*; D012008:Recurrence; D012189:Retrospective Studies
D000908:Antibodies, Fungal