[Inflammation in peritoneal dialysis].
In patients on peritoneal dialysis, peritoneal membrane alterations with inadequate peritoneal membrane function may be induced during long-term therapy. Chronic inflammation triggers malnutrition and atherosclerotic cardiovascular disease contributing to high mortality. The role of catheter, peritonitis and peritoneal dialysis fluids is argued. A neutral pH, a lesser presence of glucose degradation products generated during heat sterilization and accelerating the production of advanced glycosylation end-products (AGEs) could be reduced with better biocompatibility of peritoneal dialysis fluids.
Ryckelynck
J Ph
JP
Service de néphrologie, dialyse et transplantation rénale, Centre hospitalier universitaire de Caen. ryckelynck-jp@chu-caen.fr
Lobbedez
Th
T
Pujo
M
M
el Haggan
W
W
Hurault de Ligny
B
B
D015415:Biomarkers / Q000097:blood; D002408:Catheters, Indwelling / Q000009:adverse effects; D015314:Dialysis Solutions / Q000494:pharmacology; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000209:etiology*; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000150:complications / Q000209:etiology; D010968:Plasticizers / Q000009:adverse effects
D015415:Biomarkers; D015314:Dialysis Solutions; D010968:Plasticizers