In vitro susceptibility testing of Geotrichum capitatum: comparison of the E-test, disk diffusion, and Sensititre colorimetric methods with the NCCLS M27-A2 broth microdilution reference method.
The in vitro activities of amphotericin B, flucytosine, fluconazole, itraconazole, and voriconazole against 23 isolates of Geotrichum capitatum were determined by the National Committee for Clinical Laboratory Standards (NCCLS) M27-A2 microdilution method and the Sensititre and agar diffusion methods. Amphotericin B and voriconazole appeared to be the more active drugs. Sensititre showed the highest rates of agreement with the NCCLS M27-A2 method.
Girmenia
C
C
Dipartimento di Biotecnologie Cellulari ed Ematologia, Università, Pfizer Italia SpA, Rome, Italy. girmenia@bce.uniroma1.it
Pizzarelli
G
G
D'Antonio
D
D
Cristini
F
F
Martino
P
P
D000935:Antifungal Agents / Q000494:pharmacology*; D003124:Colorimetry; D004058:Diffusion; D005848:Geotrichum / Q000187:drug effects*; D007201:Indicator Dilution Techniques; D008826:Microbial Sensitivity Tests / Q000379:methods*
D000935:Antifungal Agents