title: The use of a distal occlusion balloon protection device in acute coronary syndrome.
abstract: We report our early experience in using the PercuSurge GuardWire Plus system as a distal protection device in patients with acute coronary syndrome and acute myocardial infarction. Forty-three patients received percutaneous coronary intervention with the GuardWire Plus system. Thirteen had unstable angina, five had non-Q myocardial infarction and 25 had ST segment elevation myocardial infarction. Forty-one target lesions were in native coronary vessels and two were in saphenous vein grafts. Total occlusion occurred in 18 patients. The mean occlusion time by the distal protective balloon was 262.8 +/- 114.1 s. Preoperatively, TIMI 0 flow was present in 18, TIMI II flow in two and TIMI III flow in 23 patients. Post-operatively, TIMI II and TIMI III flow were established in two and 41 patients, respectively. All procedures were successful and the GuardWire Plus system was successfully deployed in all but two patients. There was no procedure-related major adverse clinical event. There was no major adverse clinical event at 30 days. There was no device-related complication. We believe that the GuardWire Plus system is safe and feasible in patients with acute coronary syndrome and acute myocardial infarction.
authors.affiliation: Division of Cardiology, Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong. listevensl@yahoo.com
authors.forename: Steven S L
authors.initials: SS
authors.lastname: Li
authors.forename: C W
authors.initials: CW
authors.lastname: Lam
authors.forename: Y C
authors.initials: YC
authors.lastname: So
authors.forename: C H
authors.initials: CH
authors.lastname: Wong
authors.forename: S F
authors.initials: SF
authors.lastname: Yiu
authors.forename: D
authors.initials: D
authors.lastname: Ho
authors.forename: K W
authors.initials: KW
authors.lastname: Chan
authors.forename: K T
authors.initials: KT
authors.lastname: Chan
mesh_terms: D000789:Angina, Unstable / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D021721:Balloon Occlusion / Q000295:instrumentation; D003327:Coronary Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*