title: A young man with a renal colic.
abstract: We report the case of a 35-year-old man with no cardiovascular morbidity, presenting with acute flank pain, microscopic haematuria and normal blood pressure. Initially diagnosed as a ureteral colic, the patient was recovered 6 weeks later with severe hypertensive crisis. Further investigations revealed a massive renal infarction secondary to medial fibromuscular dysplasia (FMD). Several aspects of this presentation are intriguing. Renal infarcts are usually seen in older patients having cardiac problems and/or major atheromatous plaques. In addition, FMD is mainly observed in young females and rarely progresses to renal artery occlusion. Furthermore, in this case, FMD remained silent until the acute renal infarction occurred, despite a significant kidney size reduction at the time of diagnosis. Finally, the observation of a delayed hypertensive response to a major renovascular insult provides incentives to discuss possible pathophysiological mechanisms involved in renovascular hypertension.
authors.affiliation: Department of Nephrology, University Hospital, Lausanne, Switzerland. frederic.barbey@chuv.hospvd.ch
authors.forename: F
authors.initials: F
authors.lastname: Barbey
authors.forename: C
authors.initials: C
authors.lastname: Matthieu
authors.forename: G
authors.initials: G
authors.lastname: Nseir
authors.forename: M
authors.initials: M
authors.lastname: Burnier
authors.forename: D
authors.initials: D
authors.lastname: Teta
mesh_terms: D000328:Adult; D003085:Colic / Q000209:etiology*; D003937:Diagnosis, Differential; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000175:diagnosis; D021501:Flank Pain / Q000209:etiology; D006801:Humans; D007238:Infarction / Q000150:complications; D007668:Kidney / Q000098:blood supply; D007674:Kidney Diseases / Q000209:etiology*; D008297:Male; D014545:Urinary Calculi / Q000175:diagnosis