Cytoskeleton and motor proteins in filamentous fungi.
In filamentous fungi, the actin cytoskeleton is required for polarity establishment and maintenance at hyphal tips and for formation of a contractile ring at sites of septation. Recently, formins have been identified as Arp (actin-related protein) 2/3-independent nucleators of actin polymerization, and filamentous fungi contain a single formin that localizes to both sites. Work on cytoplasmic dynein and members of the kinesin and myosin families of motors has continued to reveal new information regarding the function and regulation of motors as well as demonstrate the importance of microtubules in the long-distance transport of vesicles/organelles in the filamentous fungi.
Xiang
Xin
X
Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. xxiang@usuhs.mil
Plamann
Michael
M
D001230:Aspergillus / Q000502:physiology*; D001692:Biological Transport; D003599:Cytoskeleton / Q000502:physiology*; D020409:Molecular Motor Proteins / Q000502:physiology*
D020409:Molecular Motor Proteins