title: Recent onset neurofibromatosis complicating eclampsia with maternal death: a case report.
abstract: Neurofibromatosis in pregnancy has been associated with poor perinatal outcome. A 30-year-old multigravida developed peripheral lesions of neurofibromatosis during the third month of pregnancy. She had eclampsia complicated with fatal left-sided massive intracerebral haemorrhage detected on computed tomography at 8.5 months gestation. Investigations were suggestive of HELLP syndrome. A still-born male baby was delivered. In spite of all supportive measures the patient died on the third postpartum day. We conclude that recent onset neurofibromatosis in current pregnancy should be considered as a predictor of potentially adverse maternal and fetal outcome and such pregnancies be managed in tertiary level referral centre.
authors.affiliation: District Hospital, Chipitola, Agra, India. agarwalumber@yahoo.co.in
authors.forename: Umber
authors.initials: U
authors.lastname: Agarwal
authors.forename: Pushpa
authors.initials: P
authors.lastname: Dahiya
authors.forename: Krishna
authors.initials: K
authors.lastname: Sangwan
mesh_terms: D000328:Adult; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D003937:Diagnosis, Differential; D004461:Eclampsia / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D017253:Neurofibromatoses / Q000150:complications*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D014057:Tomography, X-Ray Computed