Photophobia in a patient with high indinavir plasma concentrations.
An HIV-infected male patient experienced photophobia after a change in dosing regimen that resulted in substantially higher indinavir plasma levels as compared with a reference population. High indinavir levels were suspected to be the cause of photophobia in this patient.
Huitema
Alwin D R
AD
Department of Pharmacy and Pharmacology, Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands. APAHU@SLZ.NL
Kuiper
Rob A J
RA
Meenhorst
Pieter L
PL
Mulder
Jan W
JW
Beijnen
Jos H
JH
D000328:Adult; D017320:HIV Protease Inhibitors / Q000009:adverse effects*; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000097:blood; D008297:Male; D020795:Photophobia / Q000139:chemically induced*
D017320:HIV Protease Inhibitors; D019469:Indinavir