Screening chemical composition and in vitro antioxidant and antimicrobial activities of the essential oils from Origanum syriacum L. growing in Turkey.
In the present study, essential oil from the leaves of Syrian oreganum [Origanum syriacum L. (Lauraceae)] grown in Turkish state forests of the Dortyol district, Turkey, was obtained by steam distillation. The chemical composition of oil was analysed by GC and GC-MS, and was found to contain 49.02% monoterpenes, 36.60% oxygenated monoterpenes and 12.59% sesquiterpenes. The major components are as follows: gamma-terpinene, carvacrol, p-cymene and beta-caryophyllene. Subsequently, the reducing power, antioxidant and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activities of the essential oil were studied. The reducing power was compared with ascorbic acid, and the other activities were compared with 2,6-di-tert-butyl-4-methyl phenol (BHT, butylated hydroxytoluene). The results showed that the activities were concentration dependent. The antioxidant activities of the oil were slightly lower than those of ascorbic acid or BHT, so the oil can be considered an effective natural antioxidant. Antimicrobial activities of the essential oil from the leaves of Origanum syriacum was also determined on 16 microorganisms tested using the agar-disc diffusion method, and showed antimicrobial activity against 13 of these.
Alma
Mehmet Hakki
MH
Department of Industrial Engineering of Forestry, Faculty of Forestry, University of Kahramanmaras Sutcu Imam, Turkey.
Mavi
Ahmet
A
Yildirim
Ali
A
Digrak
Metin
M
Hirata
Toshifumi
T
D000667:Ampicillin / Q000494:pharmacology / Q000592:standards; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology / Q000592:standards; D001713:Biphenyl Compounds; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D016166:Free Radical Scavengers / Q000494:pharmacology; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000254:growth & development; D016982:Micrococcus luteus / Q000187:drug effects / Q000254:growth & development; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009761:Nystatin / Q000494:pharmacology / Q000592:standards; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031341:Origanum / Q000737:chemistry*; D010851:Picrates / Q000494:pharmacology / Q000592:standards; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013307:Streptomycin / Q000494:pharmacology / Q000592:standards; D014421:Turkey
D000890:Anti-Infective Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D016166:Free Radical Scavengers; D039821:Monoterpenes; D009822:Oils, Volatile; D010851:Picrates; D010938:Plant Oils; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D009761:Nystatin; C007210:4-cymene; C018669:gamma-terpinene; D000667:Ampicillin; C073316:carvacrol; C024714:caryophyllene; C004931:1,1-diphenyl-2-picrylhydrazyl; D001205:Ascorbic Acid; D013307:Streptomycin