title: New minor taxane derivatives from the needles of Taxus canadensis.
abstract: Seven minor taxane derivatives were isolated for the first time from the needles of Taxus canadensis. Four of these natural taxanes are O-glycosylated (1-4), with 4 being the only reported taxane with a glucose on ring C, and two have a dimethylamino-C-5 side chain (5 and 6). An unusual double bond at C-5(6) has been identified in taxane 7.
authors.affiliation: Human Health Research Center, INRS-Institut Armand-Frappier, Université du Québec, 531 Boulevard des Prairies, Laval, Québec, Canada H7V 1B7.
authors.forename: Qing-Wen
authors.initials: QW
authors.lastname: Shi
authors.forename: Françoise
authors.initials: F
authors.lastname: Sauriol
authors.forename: Orval
authors.initials: O
authors.lastname: Mamer
authors.forename: Lolita O
authors.initials: LO
authors.lastname: Zamir
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification*; D002170:Canada; D002851:Chromatography, High Pressure Liquid; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D043823:Taxoids; D020946:Taxus / Q000737:chemistry*
chemical_list: D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane