Phenolic compounds from Anaphalis aureo-punctata.
From the ethanolic extract of the whole plant of Anaphalis aureo-punctata, a new acylated flavonoid glycoside 3-O-kaempferol-3-O-acetyl-6-O-(p-coumaroyl)-beta-D-glucopyranoside (1), and five known phenolic compounds were isolated. Their structures were established by spectral methods (UV, IR, MS, 1D, 2D-NMR). The flavonoid glycosides, 1, 2 and 3 showed markedly inhibited oxidative DNA strand breaks induced by Fenton reaction and NADH/PMS in a concentration-dependent manner.
Wu
Yan-Qi
YQ
National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China. wu_yqi@sina.com
Li
Ya
Y
Lin
Xian-Feng
XF
Liu
Zhong-Li
ZL
Li
Yu
Y
D019659:Asteraceae / Q000737:chemistry*; D004249:DNA Damage / Q000187:drug effects; D004121:Dimethyl Sulfoxide; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009904:Optical Rotation; D018384:Oxidative Stress / Q000187:drug effects; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D007202:Indicators and Reagents; D010636:Phenols; D010936:Plant Extracts; D004121:Dimethyl Sulfoxide