QSAR study on 5-lipoxygenase inhibitors using distance-based topological indices.
QSAR study on a large set of 5-lipoxygenase inhibitors has been carried out using distance-based topological indices. Regression analysis of the data has indicated that an excellent model is obtained when these topological indices are combined with some classical molecular descriptors. The obtained models are critically discussed and examined.
Agrawal
Vijay K
VK
QSAR and Computer Chemical Laboratories, APS University, Rewa-486 003, India.
Bano
Shahnaz
S
Khadikar
Padmakar V
PV
D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D008956:Models, Chemical; D015394:Molecular Structure; D021281:Quantitative Structure-Activity Relationship; D012044:Regression Analysis
D016859:Lipoxygenase Inhibitors