Ultrafast chemistry: cobalt carbonyl-mediated synthesis of diaryl ketones under microwave irradiation.
By combining the advantages of metal activation, in situ carbon monoxide delivery, and microwave heating, benzophenones were efficiently synthesized in 6-10 s. These ultrafast carbonylation reactions occur under air by flash heating of aryl iodides in the presence of dicobalt octacarbonyl. [reaction: see text]
Enquist
Per-Anders
PA
Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala Biomedical Center, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Nilsson
Peter
P
Larhed
Mats
M