New approach for the synthesis of isoxazoline-N-oxides.
A strategy for the synthesis of isoxazoline-N-oxides (cyclic five-membered nitronates) from primary nitro compounds and olefins is described. The key step of the process involves 1,3-dipolar cycloaddition of corresponding 1-bromosilyl nitronates with alkenes. [reaction: see text]
Kunetsky
Roman A
RA
N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation.
Dilman
Alexander D
AD
Ioffe
Sema L
SL
Struchkova
Marina I
MI
Strelenko
Yury A
YA
Tartakovsky
Vladimir A
VA