title: Asymptomatic middle cerebral artery stenosis diagnosed by magnetic resonance angiography.
abstract: We reviewed 1440 MRA studies to identify patients with middle cerebral artery stenosis (MCAS). We identified 99 cases, and after reviewing the clinical records, classified 28 as asymptomatic MCAS (AMCAS), a prevalence of 2%. Suspected stroke was the most frequent indication for MRA. Follow-up was available for 21, mean 46.7 months (range 2.4-75.6 months). One stroke occurred in the AMCAS territory (5%), other strokes in five patients (24%). There were five deaths in patients with MCAS; age > 69 (P = 0.045) was the only associated risk factor. This study suggests that patients in whom MRA is performed and shows AMCAS may be at increased risk of strokes in any vascular distribution or of death.
authors.affiliation: Department of Neurology, University Hospitals of Cleveland/Case Western Reserve University School of Medicine, Ohio, USA. ozaidat@hotmail.com
authors.forename: O O
authors.initials: OO
authors.lastname: Zaidat
authors.forename: D B
authors.initials: DB
authors.lastname: Zahuranec
authors.forename: E E
authors.initials: EE
authors.lastname: Ubogu
authors.forename: J A
authors.initials: JA
authors.lastname: Fernandes-Filho
authors.forename: J I
authors.initials: JI
authors.lastname: Suárez
authors.forename: J L
authors.initials: JL
authors.lastname: Sunshine
authors.forename: R W
authors.initials: RW
authors.lastname: Tarr
authors.forename: S
authors.initials: S
authors.lastname: Mirarchi
authors.forename: S G
authors.initials: SG
authors.lastname: Nour
authors.forename: W R
authors.initials: WR
authors.lastname: Selman
authors.forename: D M D
authors.initials: DM
authors.lastname: Landis
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002539:Cerebral Arterial Diseases / Q000175:diagnosis*; D003251:Constriction, Pathologic / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D020521:Stroke / Q000209:etiology*