Affected-sib-pair data can be used to distinguish two-locus heterogeneity from two-locus epistasis.
Cordell
Heather J
HJ
D003627:Data Interpretation, Statistical; D004843:Epistasis, Genetic; D030342:Genetic Diseases, Inborn / Q000235:genetics; D008040:Genetic Linkage; D016013:Likelihood Functions; D008957:Models, Genetic; D019683:Penetrance; D035781:Siblings