title: Influence of fasting status on the effects of coconut oil on chick plasma and lipoprotein composition.
abstract: For a better understanding of the hyperlipidemic function of saturated fat, we have studied the effects of diet supplementation with 10-20% coconut oil on the chick plasma and lipoprotein composition under postprandial and starvation conditions. A significant hypercholesterolemia was found in chicks fed the standard diet after 12 h of food deprivation. In these conditions, LDL-cholesterol also increased, whereas triglyceride levels were reduced in HDL, VLDL and chylomicron fractions. Coconut oil induced a significant hypercholesterolemia under both conditions, also increasing the plasma triglyceride content under postprandial conditions, but not after starvation. Coconut oil feeding increased all the chemical components of HDL, especially under postprandial conditions, but did not affect the HDL-triglycerides under food-deprivation conditions. Total cholesterol and triglyceride levels in LDL increased after coconut oil supplementation to the diet. Differences were more pronounced under postprandial conditions. Changes in VLDL and chylomicron composition were less evident.
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of Granada, 18071 Granada, Spain.
authors.forename: E
authors.initials: E
authors.lastname: García-Fuentes
authors.forename: A
authors.initials: A
authors.lastname: Gil-Villarino
authors.forename: M F
authors.initials: MF
authors.lastname: Zafra
authors.forename: E
authors.initials: E
authors.lastname: García-Peregrín
mesh_terms: D000818:Animals; D002645:Chickens; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D000074263:Coconut Oil; D004041:Dietary Fats / Q000097:blood; D005215:Fasting / Q000502:physiology*; D006937:Hypercholesterolemia / Q000097:blood; D008297:Male; D010938:Plant Oils / Q000494:pharmacology*; D019518:Postprandial Period
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D004041:Dietary Fats; D010938:Plant Oils; D002784:Cholesterol; D000074263:Coconut Oil