title: Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine.
authors.forename: S A
authors.initials: SA
authors.lastname: Lipton
authors.forename: H-S V
authors.initials: HS
authors.lastname: Chen
mesh_terms: D003704:Dementia / Q000188:drug therapy*; D016503:Drug Delivery Systems / Q000379:methods; D015195:Drug Design; D006801:Humans; D008559:Memantine / Q000494:pharmacology* / Q000627:therapeutic use; D018696:Neuroprotective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors*
chemical_list: D018696:Neuroprotective Agents; D016194:Receptors, N-Methyl-D-Aspartate; D008559:Memantine