title: Antibacterial and antiproliferative activity of cationic fullerene derivatives.
abstract: We examined the antibacterial and antiproliferative activities of alkylated C(60)-bis(N,N-dimethylpyrrolidinium iodide) derivatives. The fullerene derivatives inhibited bacteria and cancer cell growth effectively. However, the fullerene derivatives with a long alkyl chain did not show antibacterial activity.
authors.affiliation: Kyoritsu College of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan. mashino-td@kyoritsu-ph.ac.jp
authors.forename: Tadahiko
authors.initials: T
authors.lastname: Mashino
authors.forename: Dai
authors.initials: D
authors.lastname: Nishikawa
authors.forename: Kyoko
authors.initials: K
authors.lastname: Takahashi
authors.forename: Noriko
authors.initials: N
authors.lastname: Usui
authors.forename: Takao
authors.initials: T
authors.lastname: Yamori
authors.forename: Masako
authors.initials: M
authors.lastname: Seki
authors.forename: Toyoshige
authors.initials: T
authors.lastname: Endo
authors.forename: Masataka
authors.initials: M
authors.lastname: Mochizuki
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D037741:Fullerenes / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D037741:Fullerenes