title: Bend ribbon-forming tetrahydrofuran amino acids.
abstract: Short oligomeric chains of C-glycosyl beta-D-arabinofuranose configured tetrahydrofuran amino acids (where the C-2 and C-5 substituents of the tetrahydrofuran ring are cis to each other) exhibit a well-defined repeating turn secondary structure stabilised by (i, i - 2) inter-residue hydrogen bonds. This is in contrast to the epimeric alpha-D-arabinofuranose oligomer (where the C-2 and C-5 substituents of the tetrahydrofuran ring are trans to each other) in which there is no indication of any secondary structure in solution.
authors.affiliation: Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford, UK OX1 3QY.
authors.forename: Martin D
authors.initials: MD
authors.lastname: Smith
authors.forename: Timothy D W
authors.initials: TD
authors.lastname: Claridge
authors.forename: Mark S P
authors.initials: MS
authors.lastname: Sansom
authors.forename: George W J
authors.initials: GW
authors.lastname: Fleet
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000596:Amino Acids; D005663:Furans; C018674:tetrahydrofuran