The use of estrogen therapy in men.
Men make estrogen throughout their lives through the bioconversion of androgens by the aromatase enzyme in gonadal, as well as peripheral, tissues. The role of estrogen in men is not well understood; however, recent research interest has focused on this intriguing question. In some areas, such as the bone and cardiovascular systems, insights are beginning to be gained. Nevertheless, the clinical use of estrogen in men is limited.
Sayed
Yasmine
Y
University of Connecticut Health Center, 263 Farmington Avenue, Farmington, Connecticut 06030-1317, USA.
Taxel
Pamela
P
D015519:Bone Density / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects; D002986:Clinical Trials as Topic; D004958:Estradiol / Q000378:metabolism / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use*; D019584:Hot Flashes / Q000188:drug therapy; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy; D012725:Sexual Behavior / Q000187:drug effects; D014189:Transsexualism / Q000188:drug therapy
D004967:Estrogens; D004958:Estradiol