title: Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.
abstract: We have cloned a novel member of the mouse protein phosphatase 2C family, PP2Ceta. Sequence analysis suggests that PP2Ceta, PP2Czeta and NERPP-2C constitute a unique subgroup of the PP2C family. PP2Ceta had extremely low activity against alpha-casein compared with PP2Calpha and was localized mainly in cell nuclei, suggesting that PP2Ceta dephosphorylates a unique nuclear protein(s) in the cells.
authors.affiliation: Department of Biochemistry, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Komaki
authors.forename: Koji
authors.initials: K
authors.lastname: Katsura
authors.forename: Motoko
authors.initials: M
authors.lastname: Ohnishi
authors.forename: Ming
authors.initials: M
authors.lastname: Guang Li
authors.forename: Masato
authors.initials: M
authors.lastname: Sasaki
authors.forename: Makoto
authors.initials: M
authors.lastname: Watanabe
authors.forename: Takayasu
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Shinri
authors.initials: S
authors.lastname: Tamura
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D020224:Expressed Sequence Tags; D008969:Molecular Sequence Data; D010749:Phosphoprotein Phosphatases / Q000235:genetics*; D000071636:Protein Phosphatase 2C
chemical_list: D010749:Phosphoprotein Phosphatases; D000071636:Protein Phosphatase 2C