In vitro and in vivo models for evaluation of GDEPT: quantifying bystander killing in cell cultures and tumors.
Wilson
William R
WR
Auckland Cancer Society Research Centre, The University of Auckland, Auckland, New Zealand.
Pullen
Susan M
SM
Hogg
Alison
A
Hobbs
Stephen M
SM
Pruijn
Frederik B
FB
Hicks
Kevin O
KO
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity; D001711:Biotransformation; D018929:Cell Culture Techniques / Q000379:methods; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D018920:Coculture Techniques; D005260:Female; D041722:Genes, Transgenic, Suicide; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008954:Models, Biological; D009369:Neoplasms / Q000188:drug therapy*; D011355:Prodrugs / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D011355:Prodrugs