[The risk factors of failed extubation after cardiac surgery in infants].
OBJECTIVE
To investigate the risk factors of failed extubation (FE) after cardiac surgery in infants.


METHODS
227 infants (< 1 year of age) who underwent congenital heart surgery in the period between January 2001 and December 2002 were included in this study. Logistic regression analysis was used to assess the risk factors of failed extubation. Odds Ratio was used to suppose the degree of relationship between FE and risk factors.


RESULTS
Out of the 227 infants undergoing congenital heart operations, 30 (13.22%) cases failed at the extubation. Risk factors for failed extubation included postoperative duration of ventilation (EOR = 12.0; 95% CI = 4.04 - 35.71; P = 0.000 9), postoperative pneumonia (EOR = 5.33; 95% CI = 1.81 - 15.68; P = 0.002) and preoperative pulmonary hypertension (EOR = 2.80; 95% CI = 1.21 - 10.45; P = 0.041). Postoperative pneumonia and preoperative pulmonary hypertension were the 2 independent risk factors for failed extubation (P < 0.05).


CONCLUSIONS
Postoperative pneumonia and preoperative pulmonary hypertension are major risk factors for failed extubation after congenital heart surgery in infants. To prevent and to treat postoperative pneumonia and pulmonary hypertensive crises will be beneficial to the successful extubation.
Shu
Qiang
Q
Children's Hospital, Zhejiang University, Hangzhou 310003, China.
Tan
Lin-hua
LH
Wu
Li-juan
LJ
Zhang
Ze-wei
ZW
Zhu
Xiong-kai
XK
Li
Jian-hua
JH
Lin
Ru
R
D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors