Evaluation of clinical types of cutaneous lichen planus in anti-hepatitis C virus seronegative and seropositive Nigerian patients.
BACKGROUND
The presentation of oral lichen planus in anti-hepatitis C virus (HCV) seropositive and seronegative patients was previously evaluated, and the keratotic form of oral lichen planus was found to be more prevalent in anti-HCV seropositive patients. This study evaluated the presentation of cutaneous lichen planus in anti-HCV seropositive and seronegative Nigerians.


METHODS
Fifty-seven Nigerians with cutaneous lichen planus were carefully examined to determine the form of lichen planus present. All were screened for the presence of anti-HCV by second-generation enzyme-linked immunosorbent assay (ELISA) and grouped as anti-HCV seropositive or anti-HCV seronegative patients.


RESULTS
Nine patients were anti-HCV positive. Seven of these seropositive patients had hypertrophic lichen planus.


CONCLUSIONS
Hypertrophic lichen planus in Nigerians is more prevalent with HCV infection.
Daramola
Olaniyi O M
OO
Dermatology Division, Department of Medicine, University College Hospital, Ibadan, Nigeria.
Ogunbiyi
Adebola O
AO
George
Adekunle O
AO
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D017676:Lichen Planus, Oral / Q000150:complications / Q000453:epidemiology*; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence
D000914:Antibodies, Viral