title: [Comparison of synthesizing Collagen I and III in periodontal ligament cells and gingival fibroblasts].
abstract: OBJECTIVE
  To investigate the different characteristics of periodontal ligament cells and gingival fibroblasts in synthesizing Collagen I and III.
  
  
  METHODS
  Periodontal ligament cells and gingival fibroblasts were cultured from the same patient and detected for expression of Collagen I and III by immunocytochemical methods.
  
  
  RESULTS
  The immunocytochemical staining showed Collagen I and III were positive in periodontal ligament cells, and mild positive in gingival fibroblasts. Statistical analysis suggested the difference between gingival fibroblasts and periodontal ligament cells.
  
  
  CONCLUSIONS
  There were differences between the periodontal ligament cells and gingival fibroblasts in synthesizing or secreting of Collagen matrix.
authors.affiliation: School of Stomatology, Shandong University, Jinan 250012, China. wangyan1965@yahoo.com.cn
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Shuo-zhi
authors.initials: SZ
authors.lastname: Wang
authors.forename: Ming-wen
authors.initials: MW
authors.lastname: Fan
authors.forename: Pi-shan
authors.initials: PS
authors.lastname: Yang
authors.forename: Shu
authors.initials: S
authors.lastname: Li
mesh_terms: D002478:Cells, Cultured; D024042:Collagen Type I / Q000032:analysis / Q000096:biosynthesis*; D024061:Collagen Type III / Q000032:analysis / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism; D005881:Gingiva / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D010513:Periodontal Ligament / Q000378:metabolism*
chemical_list: D024042:Collagen Type I; D024061:Collagen Type III