title: Extraintestinal pathogenic Escherichia coli as a cause of invasive nonurinary infections.
abstract: Multiple Escherichia coli isolates from four adults with extraintestinal infections underwent molecular phylotyping and virulence profiling. A patient with secondary peritonitis had two low-virulence E. coli strains from phylogenetic groups A and D. In contrast, three patients with invasive extraurinary infections (septic arthritis/pyomyositis, nontraumatic meningitis/hematogenous osteomyelitis, and pneumonia) each had a single high-virulence phylogenetic group B2 strain resembling typical isolates causing urinary infection and/or sepsis, i.e., extraintestinal pathogenic E. coli.
authors.affiliation: Mucosal and Vaccine Research Center, VA Medical Center, University of Minnesota, Minneapolis, Minnesota 55417, USA. johns007@umn.edu
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
authors.forename: Abby
authors.initials: A
authors.lastname: Gajewski
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Lesse
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Russo
mesh_terms: D000368:Aged; D001483:Base Sequence; D017931:DNA Primers; D004926:Escherichia coli / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000382:microbiology / Q000473:pathology; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000379:methods
chemical_list: D017931:DNA Primers