title: [A case of gastric carcinoma with multiple skin, bone, and bilateral ovary metastasis; effective treatment by chemotherapy].
abstract: A 40-year-old female visited our hospital with general malaise. She was diagnosed with gastric carcinoma with multiple skin, bone, and bilateral ovary metastases. Chemotherapy with 5-FU (1,000 mg/w) and cisplatin (10 mg/w) was performed in the outpatient clinic. Two years after the initial diagnosis, CEA was elevated. She then was given chemotherapy of CPT-11 (40 mg/w) in the outpatient clinic after 1 cycle of combined chemotherapy of CPT-11 and cisplatin. She died 38 months after the initial diagnosis. Weekly 5-FU/CDDP or low-dose CPT-11 appear to be effective for such a gastric carcinoma with systemic metastases without impairing quality of life.
authors.affiliation: Dept. of Gastroenterology Tokeidai Hospital.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Mezawa
authors.forename: Hisato
authors.initials: H
authors.lastname: Homma
authors.forename: Tadashi
authors.initials: T
authors.lastname: Doi
authors.forename: Takehide
authors.initials: T
authors.lastname: Akiyama
authors.forename: Ken
authors.initials: K
authors.lastname: Murakami
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Kogawa
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hirata
authors.forename: Masaya
authors.initials: M
authors.lastname: Kida
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Murase
authors.forename: Satoshi
authors.initials: S
authors.lastname: Iyama
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000556:secondary*; D011379:Prognosis; D011788:Quality of Life; D012878:Skin Neoplasms / Q000188:drug therapy / Q000556:secondary*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000077146:Irinotecan; D002945:Cisplatin; D005472:Fluorouracil; D002166:Camptothecin