Current management of atopic dermatitis and interruption of the atopic march.
Treatment of atopic dermatitis requires a comprehensive approach that includes evaluation of potential triggers and education of the patient and family regarding proper avoidance measures. Hydration of the skin and maintenance of an intact skin barrier remain integral to proper management. Although topical corticosteroids have been a mainstay of anti-inflammatory therapy, the newer topical calcineurin inhibitors offer advantages for treatment of this chronic, relapsing disease. Studies aimed at defining optimal combination therapy and early intervention might change the treatment paradigm for atopic dermatitis.
Boguniewicz
Mark
M
Division of Pediatric Allergy-Immunology, National Jewish Medical Research Center and University of Colorado School of Medicine, Denver, Colorado 80206, USA.
Eichenfield
Lawrence F
LF
Hultsch
Thomas
T
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000517:prevention & control; D019703:Calcineurin / Q000627:therapeutic use; D065095:Calcineurin Inhibitors; D003876:Dermatitis, Atopic / Q000628:therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use; D019468:Disease Management; D018450:Disease Progression; D006801:Humans; D015995:Prevalence; D017592:Skin Care / Q000639:trends
D000893:Anti-Inflammatory Agents; D065095:Calcineurin Inhibitors; D003879:Dermatologic Agents; D019703:Calcineurin