Isolation and structures of new halogenated prostanoids from the Okinawan soft coral Clavularia viridis.
Fifteen new halogenated prostanoids 9-23 were isolated as minor constituents from the Okinawan soft coral Clavularia viridis. Compounds 9-11 were new members of iodovulone, and compounds 12-18 were 12-O-acetyliodovulones, 12-O-acetylbromovulones, and 12-O-acetylchlorovulones. Compounds 19-23 were 10,11-epoxy congeners of iodovulone, bromovulone, and chlorovulone. The structures of these compounds were determined on the basis of spectroscopic analysis and chemical conversion.
Watanabe
Kinzo
K
School of Life Science, Tokyo University of Pharmacy and Life Science, Horinouchi, Hachioji, Tokyo 192-0392, Japan. onocerin@ls.toyaku.ac.jp
Sekine
Miyuki
M
Iguchi
Kazuo
K
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry* / Q000302:isolation & purification*; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011453:Prostaglandins / Q000737:chemistry* / Q000302:isolation & purification*
D006846:Hydrocarbons, Halogenated; D011453:Prostaglandins