Tumor sensitization to purine analogs by E. coli PNP.
Curlee
Kimberly V
KV
Department of Human Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.
Parker
William B
WB
Sorscher
Eric J
EJ
D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use; D001711:Biotransformation; D024201:Bystander Effect / Q000502:physiology; D002470:Cell Survival; D043525:Cytosine Deaminase / Q000235:genetics / Q000627:therapeutic use; D004926:Escherichia coli / Q000201:enzymology*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D011355:Prodrugs / Q000493:pharmacokinetics* / Q000627:therapeutic use; D011683:Purine-Nucleoside Phosphorylase / Q000378:metabolism*; D011687:Purines / Q000378:metabolism*; D018139:Simplexvirus / Q000201:enzymology; D013937:Thymidine Kinase / Q000235:genetics / Q000627:therapeutic use; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D011355:Prodrugs; D011687:Purines; D011683:Purine-Nucleoside Phosphorylase; D013937:Thymidine Kinase; D043525:Cytosine Deaminase