title: [The risk factors of failed extubation after cardiac surgery in infants].
abstract: OBJECTIVE
  To investigate the risk factors of failed extubation (FE) after cardiac surgery in infants.
  
  
  METHODS
  227 infants (< 1 year of age) who underwent congenital heart surgery in the period between January 2001 and December 2002 were included in this study. Logistic regression analysis was used to assess the risk factors of failed extubation. Odds Ratio was used to suppose the degree of relationship between FE and risk factors.
  
  
  RESULTS
  Out of the 227 infants undergoing congenital heart operations, 30 (13.22%) cases failed at the extubation. Risk factors for failed extubation included postoperative duration of ventilation (EOR = 12.0; 95% CI = 4.04 - 35.71; P = 0.000 9), postoperative pneumonia (EOR = 5.33; 95% CI = 1.81 - 15.68; P = 0.002) and preoperative pulmonary hypertension (EOR = 2.80; 95% CI = 1.21 - 10.45; P = 0.041). Postoperative pneumonia and preoperative pulmonary hypertension were the 2 independent risk factors for failed extubation (P < 0.05).
  
  
  CONCLUSIONS
  Postoperative pneumonia and preoperative pulmonary hypertension are major risk factors for failed extubation after congenital heart surgery in infants. To prevent and to treat postoperative pneumonia and pulmonary hypertensive crises will be beneficial to the successful extubation.
authors.affiliation: Children's Hospital, Zhejiang University, Hangzhou 310003, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Shu
authors.forename: Lin-hua
authors.initials: LH
authors.lastname: Tan
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: Wu
authors.forename: Ze-wei
authors.initials: ZW
authors.lastname: Zhang
authors.forename: Xiong-kai
authors.initials: XK
authors.lastname: Zhu
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Li
authors.forename: Ru
authors.initials: R
authors.lastname: Lin
mesh_terms: D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors