title: [Catastrophic antiphospholipid syndrome in the immediate puerperium].
abstract: We describe a female previously diagnosed of primary antiphospholipid antibody syndrome who presented a preclampsia in the second pregnancy. An urgent caesaria was made because of a worsening high blood pressure and oliguria. In the immediated puerperium she showed low platelets and persistent high blood pressure. Afterwards acute renal failure and neurological signs with a severe aortic valvulopathy were diagnosed. An haemolytic anemia was also detected. Definitive diagnosis was made by kidney biopsy with the result of a thrombotic microangiopathy. Treatment with low weight heparin and aspirin and systemic corticosteroids was started in the immediate puerperium and fresh frozen plasma was then added with a good response to treatment. Actually she is still with high blood pressure, aortic valvulopathy. Renal function is normal one year later.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Doctor Josep Trueta, Girona.
authors.forename: P
authors.initials: P
authors.lastname: Ortiz
authors.forename: A
authors.initials: A
authors.lastname: Castro
authors.forename: M
authors.initials: M
authors.lastname: Vallés
authors.forename: E
authors.initials: E
authors.lastname: Coll
authors.forename: M
authors.initials: M
authors.lastname: Casas
authors.forename: J M
authors.initials: JM
authors.lastname: Mauri
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000097:blood / Q000378:metabolism; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications; D011644:Puerperal Disorders / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D017152:Antibodies, Antiphospholipid