title: Successful management of a pregnant woman with heterozygous protein C deficiency using activated protein C concentrate.
abstract: Heterozygous protein C deficiency frequently causes deep vein thrombosis during pregnancy. We report the successful management of delivery using activated protein C concentrate in a patient with heterozygous protein C deficiency, who developed deep vein thrombosis in mid gestation.
authors.affiliation: Department of Gynecology and Obstetrics, Clinical Sciences for Pathological Organs, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Kentaroh
authors.initials: K
authors.lastname: Sekiyama
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Itoh
authors.forename: Norimasa
authors.initials: N
authors.lastname: Sagawa
authors.forename: Keiji
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takayama
authors.forename: Shingo
authors.initials: S
authors.lastname: Fujii
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D005268:Femoral Vein; D006579:Heterozygote; D006801:Humans; D011152:Popliteal Vein; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000209:etiology; D011486:Protein C / Q000627:therapeutic use*; D020151:Protein C Deficiency / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000925:Anticoagulants; D011486:Protein C