title: Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries.
abstract: The true 3-dimensional neointimal thickness distribution in sirolimus-eluting stents was investigated in relation to the shear stress distribution, which was obtained from computational fluid dynamics calculations. Small pits were observed between the stent struts in all patients, and a significant inverse relation between neointimal thickness and shear stress was found, indicating that deeper pits were present in the outside curve of the stented segments.
authors.affiliation: Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands. f.gijsen@erasmusmc.nl
authors.forename: Frank J H
authors.initials: FJ
authors.lastname: Gijsen
authors.forename: Remko M
authors.initials: RM
authors.lastname: Oortman
authors.forename: Jolanda J
authors.initials: JJ
authors.lastname: Wentzel
authors.forename: Johan C H
authors.initials: JC
authors.lastname: Schuurbiers
authors.forename: Kengo
authors.initials: K
authors.lastname: Tanabe
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Degertekin
authors.forename: Jurgen M
authors.initials: JM
authors.lastname: Ligthart
authors.forename: Attila
authors.initials: A
authors.lastname: Thury
authors.forename: Pim J
authors.initials: PJ
authors.lastname: de Feyter
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
authors.forename: Cornelis J
authors.initials: CJ
authors.lastname: Slager
mesh_terms: D001783:Blood Flow Velocity; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000628:therapy; D003331:Coronary Vessels / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D017539:Tunica Intima / Q000473:pathology*
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus