[Trabeculectomy with amniotic membrane transplantation and combining suture lysis of scleral flap in complicated glaucoma].
OBJECTIVE
To study and evaluate the outcome of trabeculectomy with amniotic membrane transplantation combining suture lysis of scleral flap in complicated glaucoma.


METHODS
This operation was performed in 48 patients (67 eyes) with complicated glaucoma. Amniotic membrane was implanted under the scleral flap and the conjunctival flap and combined with suture lysis for scleral flap to control the outflow of the aqueous humor.


RESULTS
Follow-up period ranged from 5 to 38 months (mean 19.5 months). The intraocular pressure (IOP) was lowered from (43.86 +/- 7.12) mm Hg (preoperative IOP) to postoperative (19.63 +/- 2.57) mm Hg (postoperative IOP) in neovascular glaucoma (t = 4.96, P < 0.001); from (40.31 +/- 4.79) mm Hg to (18.09 +/- 2.21) mm Hg in glaucoma after IOL implant (t = 3.54, P < 0.05); from (37.94 +/- 5.63) mm Hg to (20.14 +/- 3.15) mm Hg in aphakic glaucoma (t = 5.12, P < 0.05); from (32.48 +/- 3.98) mm Hg to (16.54 +/- 1.84) mm Hg in juvenile glaucoma (t = 4.23, P < 0.01); from (36.01 +/- 4.13) mm Hg to (18.11 +/- 3.40) mm Hg in uveitic glaucoma (t = 4.47, P < 0.01); from (34.43 +/- 5.28) mm Hg to (18.31 +/- 1.52) mm Hg in glaucoma after failure of conventional filtering operation (t = 2.05, P < 0.05). Statistical significant difference was found in the IOP before and after the operation. The rate of formation of functional bulb was 80.6%. There were no reject reaction and severe complications.


CONCLUSIONS
Trabeculectomy with amniotic membrane transplantation combining suture lysis of scleral flap is a useful method in complicated glaucoma.
Yue
Jun
J
Department of Ophthalmology, Ren He Hospital, China Three Gorges University, Yichang 443001, China. yuejun650304@163.com
Hu
Chang-qing
CQ
Lei
Xiao-min
XM
Qin
Guang-hai
GH
Zhang
Yan
Y
D000293:Adolescent; D000328:Adult; D000650:Amnion / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012590:Sclera / Q000601:surgery*; D013536:Suture Techniques; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome