[Study on supercritical CO2 extracting conditions on Phyllanthus urinaria].
The technology for extracting Phyllanthus urinaria L. with supercritical CO2 as a solvent was described. The effect of extraction pressure, extraction temperature, extraction time and 85% ethanol-H2O co-solvent capacity have been studied. The proper technology requirements were determined through orthogonal experiment and the result shows the rate of extraction can be up to 9.0 percent, after extracting for 2.5 hours under the condition of extraction pressure 18 MPa, extraction temperature 50 degrees C, separation temperature 42 degrees C, separation pressure 5.8 +/- 0.2 MPa and CO2 flux 3.0 +/- 0.2 L/h.
Chen
Jianhua
J
School of Chemical Engineering, South China University of Technology, Guangzhou 510640.
Huang
Shaolie
S
Zhu
Baozhang
B
D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D029803:Phyllanthus / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D013696:Temperature; D013997:Time Factors
D004365:Drugs, Chinese Herbal; D002245:Carbon Dioxide