title: [Pulmonary hyalinising granuloma with mediastinal fibrosis: a rare cause of dysphagia].
abstract: Pulmonary hyalinising granulomas (PHG) are rare. They are defined by the presence of collagen lamellar fibrosis. One third are associated with retroperitoneal or mediastinal fibrosis. Two cases of PHG are presented. They were revealed by dysphagia due to tight oesophageal stricture from associated mediastinal fibrosis. PHG are considered as a benign and slowly evolving disease, but associated mediastinal fibrosis may evolve on its own. Only steroid therapy may slow down progression. This makes an accurate diagnosis necessary. It relies on large surgical biopsies.
authors.affiliation: Département thoracique, institut Mutualiste-Montsouris, 42, boulevard Jourdan, 75014, Paris, France. dominique.gossot@imm.fr
authors.forename: D
authors.initials: D
authors.lastname: Gossot
authors.forename: G
authors.initials: G
authors.lastname: Fromont
authors.forename: D
authors.initials: D
authors.lastname: Galetta
authors.forename: D
authors.initials: D
authors.lastname: Debrosse
authors.forename: D
authors.initials: D
authors.lastname: Grunenwald
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D003680:Deglutition Disorders / Q000209:etiology*; D018450:Disease Progression; D004940:Esophageal Stenosis / Q000209:etiology*; D005260:Female; D005355:Fibrosis / Q000150:complications; D015769:Granuloma, Respiratory Tract / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008482:Mediastinum / Q000473:pathology*; D015641:Radiography, Interventional; D035583:Rare Diseases; D012720:Severity of Illness Index; D013906:Thoracoscopy; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents