title: Pax gene expression in the developing central nervous system of Ciona intestinalis.
abstract: We compare the expression patterns in Ciona intestinalis of three members of the Pax gene family, CiPax3/7, CiPax6 and Cipax2/5/8. All three genes are expressed in restricted patterns in the developing central nervous system. At the tailbud stage, CiPax3/7 is present in three patches in the brain and along the posterior neural tube, CiPax6 throughout the anterior brain and along the posterior neural tube and CiPax2/5/8 in a restricted region of the posterior brain. Double in situ hybridisations were used to identify areas of overlap between the expression of different genes. This showed that CiPax3/7 overlaps with the boundaries of CiPax6 expression in the anterior brain, and with CiPax2/5/8 in the posterior brain. The overlap between CiPax3/7 and CiPax2/5/8 is unlike that described in the ascidian Halocynthia rorezti.
authors.affiliation: School of Animal and Microbial Sciences, The University of Reading, P.O. Box 228, Whiteknights, RG6 6AJ, Reading, UK. f.mazet@reading.ac.uk
authors.forename: Françoise
authors.initials: F
authors.lastname: Mazet
authors.forename: James A
authors.initials: JA
authors.lastname: Hutt
authors.forename: John
authors.initials: J
authors.lastname: Millard
authors.forename: Sebastian M
authors.initials: SM
authors.lastname: Shimeld
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000196:embryology* / Q000254:growth & development* / Q000378:metabolism; D002938:Ciona intestinalis / Q000196:embryology* / Q000254:growth & development* / Q000378:metabolism; D005136:Eye Proteins; D015870:Gene Expression; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D012097:Repressor Proteins; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D005136:Eye Proteins; D018398:Homeodomain Proteins; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D012097:Repressor Proteins; D014157:Transcription Factors