title: Time interval of oral feeding recovery as a prognostic factor in severe traumatic brain injury.
abstract: OBJECTIVE
  To assess the outcome of severe traumatic brain injury at least 1 year after trauma, in relation to some early clinical prognostic factors occurring during coma recovery.
  
  
  METHODS
  Retrospective study conducted at the post-coma unit of a rehabilitation hospital.
  
  
  METHODS
  A total of 43 patients were included. All of the patients sustained severe traumatic brain injury and prolonged coma, i.e. coma lasting at least 15 days. Outcome was assessed by means of Glasgow Coma Scale, Barthel Index and Mini Mental State 1 year after trauma, in relation to some early clinical prognostic factors occurring during coma recovery.
  
  
  RESULTS
  At the 1 year follow-up, a statistically significant correlation was found with both the Glasgow Outcome Scale and the Barthel Index for the time interval from brain injury to recovery of the following clinical variables: optical fixation, ability to obey commands, spontaneous motor activity and first safe oral feeding. Psychomotor agitation and bulimia were also favourable prognostic factors for the final outcome.
  
  
  CONCLUSIONS
  In the present study, first safe oral feeding during coma recovery represents the clinical feature that better predicts the final outcome of patients with severe traumatic brain injury and prolonged coma.
authors.affiliation: IRCCS Fondazione Santa Lucia, Rome, Italy. r.formisano@hsantalucia.it
authors.forename: R
authors.initials: R
authors.lastname: Formisano
authors.forename: R D
authors.initials: RD
authors.lastname: Voogt
authors.forename: M G
authors.initials: MG
authors.lastname: Buzzi
authors.forename: V
authors.initials: V
authors.lastname: Vinicola
authors.forename: F
authors.initials: F
authors.lastname: Penta
authors.forename: A
authors.initials: A
authors.lastname: Peppe
authors.forename: P
authors.initials: P
authors.lastname: Stanzione
mesh_terms: D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000534:rehabilitation*; D002648:Child; D004435:Eating; D005260:Female; D005500:Follow-Up Studies; D023261:Glasgow Outcome Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D020127:Recovery of Function; D012189:Retrospective Studies; D013997:Time Factors