Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms.
A method for automatic volume segmentation of functional imaging based on a relationship between source-to-background ratio and the iso-activity level to be used is described. Such method, which has been established with radioactive spheres in a phantom, is independent of the a priori knowledge of the lesion of interest and is valid for small (>2 ml) and/or poorly contrasted (S/B>1.5) lesions. Accuracy varies slightly with the image reconstruction algorithm used.
Daisne
Jean-François
JF
Department of Radiation Oncology, Laboratory of Radiobiology, Université catholique de Louvain, St-Luc University Hospital, 10 Ave Hippocrate, B-1200 Brussels, Belgium.
Sibomana
Mérence
M
Bol
Anne
A
Doumont
Thomas
T
Lonneux
Max
M
Grégoire
Vincent
V
D000465:Algorithms; D019047:Phantoms, Imaging; D014055:Tomography, Emission-Computed / Q000379:methods*