title: Secular trends in a population with ischemic heart disease admitted to the Instituto do Coração in São Paulo.
abstract: OBJECTIVE
  To assess the clinical and demographic characteristics of a population with ischemic heart disease admitted in the final decades of the 20th century.
  
  
  METHODS
  This study retrospectively assessed patients hospitalized with ischemic heart disease divided into the following 2 groups: acute group - 11.181 patients with acute myocardial infarction admitted from 1/1/82 to 12/31/94; and chronic group - 4.166 patients undergoing coronary artery bypass graft surgery from 1/1/84 to 12/31/94.
  
  
  RESULTS
  In the acute group, an increase in the percentage of females (from 22.7% to 27.7%, P<0.001) and diabetic individuals (from 12.4% to 17.5%, P<0.001) was observed, as was an increase in age (from 57.4 +/- 11.5 to 59.9 +/- 12.1 years, P<0.05). In-hospital mortality was greater among females (27.8% and 15.7%, P=0.001), among diabetic individuals (24.2% and 17.8%, P=0.001), and among the elderly (60.9 +/- 15.2 and 57.7 +/- 11.8 years, P=0.0001). In the chronic group, an increase in the percentage of females (from 17.5% to 27.2%, P=0.001) was observed, as was an increase in age (from 56.3 +/- 8.6 to 60.5 +/- 9.6 years, P=0.0001). In-hospital mortality was greater among females (8.3% and 5.8%, P<0.05) and among the elderly (58.1 +/- 9.1 and 62.1 +/- 7.9 years, P=0.0001).
  
  
  CONCLUSIONS
  The characteristics of the population studied with ischemic heart disease point towards a worse prognosis, due to the greater percentages of females, older patients, and diabetic patients, groups known to have greater in-hospital mortality.
authors.affiliation: FMUSP, Instituto do Coração do Hospital das Clínicas, São Paulo, SP, Brazil. bcaramel@incor.usp.br
authors.forename: Bruno
authors.initials: B
authors.lastname: Caramelli
authors.forename: Luciana Savoy
authors.initials: LS
authors.lastname: Fornari
authors.forename: Maristela
authors.initials: M
authors.lastname: Monachini
authors.forename: Dália
authors.initials: D
authors.lastname: Ballas
authors.forename: Nilson Roberto
authors.initials: NR
authors.lastname: Fachini
authors.forename: Antônio de Pádua
authors.initials: Ade P
authors.lastname: Mansur
authors.forename: José Antônio Franchini
authors.initials: JA
authors.lastname: Ramires
mesh_terms: D000208:Acute Disease; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002908:Chronic Disease; D001026:Coronary Artery Bypass / Q000401:mortality; D005260:Female; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D017678:Sex Distribution