title: Usefulness of coronary flow reserve measured by transthoracic coronary Doppler ultrasound to detect severe left anterior descending coronary artery stenosis.
abstract: Transthoracic coronary Doppler ultrasound during venous adenosine infusion showed damped (<1) coronary flow velocity reserve in patients with severe left anterior descending coronary artery stenosis. Damped coronary flow reserve discriminated severe from nonsevere stenosis with high sensitivity, specificity, and positive predictive accuracy, and is a unique noninvasive tool to identify high-risk patients.
authors.affiliation: University of Rome La Sapienza, Rome, Italy. voci@uniroma1.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Voci
authors.forename: Francesco
authors.initials: F
authors.lastname: Pizzuto
authors.forename: Enrica
authors.initials: E
authors.lastname: Mariano
authors.forename: Paolo Emilio
authors.initials: PE
authors.lastname: Puddu
authors.forename: Gennaro
authors.initials: G
authors.lastname: Sardella
authors.forename: Francesco
authors.initials: F
authors.lastname: Romeo
mesh_terms: D000241:Adenosine / Q000008:administration & dosage; D000368:Aged; D000704:Analysis of Variance; D001783:Blood Flow Velocity; D016009:Chi-Square Distribution; D003326:Coronary Circulation / Q000502:physiology*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004452:Echocardiography / Q000379:methods; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D014665:Vasodilator Agents; D000241:Adenosine