title: A new family with the rare genodermatosis keratosis punctata palmoplantaris Buschke-Fischer-Brauer.
abstract: We describe a new family with the rare genodermatosis keratosis punctata palmo-plantaris Buschke-Fischer-Brauer (keratoma disseminatum). In all, 3 family members in 3 generations were affected, a pattern consistent with autosomal dominant inheritance. Clinical symptoms started in the third decade with disseminated, small, round, hyperkeratotic papules on the palms and soles. Punctate keratoses coalesced into hyperkeratotic plaques on pressure points. Identification of additional families is necessary to permit definitive genetic classification of this genodermatosis.
authors.affiliation: Department of Dermatology, University of Göttingen, von-Siebold-Strasse 3, 37075 Göttingen, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Emmert
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Küster
authors.forename: Markus
authors.initials: M
authors.lastname: Zutt
authors.forename: Holger
authors.initials: H
authors.lastname: Hänssle
authors.forename: Christian
authors.initials: C
authors.lastname: Hallermann
authors.forename: Lutz
authors.initials: L
authors.lastname: Kretschmer
authors.forename: Christine
authors.initials: C
authors.lastname: Neumann
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007223:Infant; D007645:Keratoderma, Palmoplantar / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010375:Pedigree