title: [Chronic gastritis in children with concomitant diseases of the thyroid gland].
abstract: We examined: 1 group--16 children with chronic gastritis (CG) and autoimmune thyroiditis (AT); 2 group--41 children with functional thyroidal pathologies; 3 group--23 children with CG only. The average age in all groups was 11.17 +/- 2.98. HP (68%) was revealed equally frequently in all the groups. Antibodies to H+/K(+)-ATPase of parietal cells were revealed in the first and second groups only (31-36%), p < 0.05 as compared to the third group. CG of the stomach body was more frequently revealed in the first group using endoscopic and histological tests. The second group had more frequent and more apparent lesions of the antral part. Thus, in case of concomitant diseases of the thyroid gland CG has an autoimmune nature of an inflammation of the mucous coat of the stomach.
authors.affiliation: I.I. Mechnikov Saint-Petersburg State Medical Academy, Children's Infectious Diseases Hospital No. 5, Institute of Toxicology, Ministry of Health of the Russian Federation, Saint-Petersburg Pediatric Medical Academy.
authors.forename: V P
authors.initials: VP
authors.lastname: Novikova
authors.forename: V V
authors.initials: VV
authors.lastname: Iur'ev
authors.forename: E I
authors.initials: EI
authors.lastname: Tkachenko
authors.forename: E L
authors.initials: EL
authors.lastname: Strukov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Liubimov
authors.forename: P V
authors.initials: PV
authors.lastname: Antonov
mesh_terms: D000293:Adolescent; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000276:immunology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005753:Gastric Mucosa / Q000276:immunology / Q000473:pathology*; D005756:Gastritis / Q000150:complications* / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D017506:H(+)-K(+)-Exchanging ATPase / Q000276:immunology; D016481:Helicobacter Infections / Q000276:immunology / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D013959:Thyroid Diseases / Q000150:complications* / Q000473:pathology*
chemical_list: D001323:Autoantibodies; D017506:H(+)-K(+)-Exchanging ATPase