title: [Spontaneous resolution of a giant pulmonary bulla].
abstract: There are different causes leading to formation of pulmonary bullae, in particular tuberculosis. There is some debate concerning the pathophysiology of bullae extension although two mechanisms are put forward: partial obstruction of the airways and elastic recoil of adjacent lung parenchyma with a negative pressure in the bullae. Pulmonary function tests are highly perturbed in patients with giant bullae. The natural history of bullae is enlargement although spontaneous regression is rarely described. Bullae should be resected in selected patients, others require careful follow-up. We present the case of a man with tuberculosis who developed a giant pulmonary bulla that regressed spontaneously in a few years.
authors.affiliation: Service de Pneumologie, Hôpital Pontchaillou, Centre Hospitalier et Universitaire de Rennes, rue Henri Le Guilloux, 35033 Rennes Cedex.
authors.forename: S
authors.initials: S
authors.lastname: Guillot
authors.forename: C
authors.initials: C
authors.lastname: Belleguic
authors.forename: J C
authors.initials: JC
authors.lastname: Renaud
authors.forename: M H
authors.initials: MH
authors.lastname: Marques
authors.forename: K
authors.initials: K
authors.lastname: Fekete
authors.forename: P
authors.initials: P
authors.lastname: Delaval
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001261:Pulmonary Atelectasis / Q000000981:diagnostic imaging; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011859:Radiography; D012075:Remission, Spontaneous; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents