title: Rheumatoid arthritis. Targeted interventions can minimize joint destruction.
abstract: Rheumatoid arthritis can cause joint erosion and deformity, pain, stiffness, and decreased function and range of motion. Early diagnosis is crucial to prevent permanent joint damage. In this article, Drs Williams and Fye discuss articular and extra-articular manifestations of rheumatoid arthritis as well as the evolving treatment approaches to this complex disease.
authors.affiliation: University of California, San Francisco, 400 Parnassus Ave, Box 0326, San Francisco, CA 94143, USA.
authors.forename: Eleanor Anderson
authors.initials: EA
authors.lastname: Williams
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Fye
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000145:classification / Q000473:pathology / Q000628:therapy*; D006801:Humans
chemical_list: D018501:Antirheumatic Agents