Tumor marker workshops.
Since 1996, the nine ISOBM Workshops have so far characterized more than 300 monoclonal antibodies to a variety of tumor markers that include CA125, AFP, PSA, MUC1, Cytokeratins, Sialyl Le(a), hCG, CEA, ALP, and more recently SCC, and S100. Besides the basic characterization of antibodies and their epitope configurations, several workshops have also addressed specific problems associated with multiple antigen variants. These workshops have been able to make significant advances well beyond those possible through any normal collaboration study. The data and impact of these workshops with their summary reports are reviewed.
Rye
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PD
Central Laboratory, Norwegian Radium Hospital, Montebello, Oslo, Norway.
Nustad
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Stigbrand
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D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D018394:CA-125 Antigen / Q000032:analysis; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000032:analysis; D005732:Gangliosides / Q000032:analysis; D006801:Humans; D007633:Keratins / Q000032:analysis; D018396:Mucin-1 / Q000032:analysis; D017430:Prostate-Specific Antigen / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D005732:Gangliosides; D018396:Mucin-1; D000509:alpha-Fetoproteins; D007633:Keratins; C064564:sialyl Le(a) ganglioside; D000469:Alkaline Phosphatase; D017430:Prostate-Specific Antigen