title: [The study on specific anti-Streptococcus mutans IgY against dental caries in rats].
abstract: OBJECTIVE
  To investigate the effect of specific anti-streptococcus mutans IgY against streptococcus mutans on dental caries development in rats.
  
  
  METHODS
  35 wistar rats were divided into 5 groups: group A received IgY gargle; group B received IgY lyophilized powder; group C received sterilized water as control; group D and E received egg yolk food with or without specific IgY individually. They were all fed with caries-inducing diet 2000#. The number of caries scores was counted by the procedure of Keyes'.
  
  
  RESULTS
  There was a significant lower mean of caries scores in groups treated with IgY lyophilized powder and gargle. By treating with egg-yolk food contained specific IgY, the mean of caries scores decreased comparing with no treatment group.
  
  
  CONCLUSIONS
  Local passive immunization with specific anti-streptococcus mutans IgY may be an effective way to prevent the development of dental caries.
authors.affiliation: Department of Endodontics, College of Stomatology, Wuhan University, Wuhan 430070, China.
authors.forename: Mingwen
authors.initials: M
authors.lastname: Fan
authors.forename: Qianzhou
authors.initials: Q
authors.lastname: Jiang
authors.forename: Zhuan
authors.initials: Z
authors.lastname: Bian
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000008:administration & dosage; D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000276:immunology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D022541:Streptococcal Vaccines / Q000276:immunology*; D013295:Streptococcus mutans / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; C016512:IgY; D007136:Immunoglobulins; D022541:Streptococcal Vaccines