title: Successful treatment of primary pulmonary angiosarcoma.
abstract: Angiosarcoma in the lung is an uncommon disorder and is usually attributable to metastasis from a primary site. Primary pulmonary angiosarcoma is extremely rare, and the prognosis of affected individuals is dismal, with most patients dying within months of presentation. Indeed, there have been no reported instances of successful treatment of this condition. We now report the case of a patient with primary pulmonary angiosarcoma who responded to a combination of radiotherapy and immunotherapy with recombinant interleukin-2. The patient remains well without signs of recurrence 1 year after initial presentation. This combination therapy may be a promising strategy to prolong the survival of patients with primary pulmonary angiosarcoma.
authors.affiliation: Department of Respiratory Medicine, Graduate School of Medical Science, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-0811, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kojima
authors.forename: Isamu
authors.initials: I
authors.lastname: Okamoto
authors.forename: Sunao
authors.initials: S
authors.lastname: Ushijima
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yoshinaga
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Kitaoka
authors.forename: Moritaka
authors.initials: M
authors.lastname: Suga
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sasaki
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D007376:Interleukin-2 / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D007376:Interleukin-2