REM sleep reduction, mood regulation and remission in untreated depression.
The contribution of increased rapid eye movement (REM) pressure through repeated, mild, reduction of (REM) sleep to remission from untreated depression was studied over a 5-month period in 20 depressed and 10 control volunteers. Sixty percent of the depressed subjects were in remission at the end of the study. Sixty-four percent of the variance in remission could be accounted for by four variables: the initial level of self-reported symptoms, the reported diurnal variability in mood, the degree of overnight reduction in depressed mood following interruptions of REM sleep and the quality of dream reports from these awakenings. Increased REM pressure is beneficial for those who are able to construct well-organized dreams.
Cartwright
Rosalind
R
Sleep Disorder Service and Research Center, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. rcartwri@rush.edu
Baehr
Erin
E
Kirkby
Jennifer
J
Pandi-Perumal
S R
SR
Kabat
Julie
J
D000328:Adult; D000339:Affect; D003863:Depression / Q000175:diagnosis / Q000523:psychology*; D004325:Dreams; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D017286:Polysomnography / Q000379:methods; D012074:Remission Induction; D012895:Sleep, REM / Q000502:physiology*; D011795:Surveys and Questionnaires; D013997:Time Factors