title: [A case of metastatic lung tumor from an occult thyroid oncocytic carcinoma growing into the bronchial lumen].
abstract: We report a case of a metastatic lung tumor from an occult thyroid oncocytic carcinoma, growing into the bronchial lumen. A 70-year-old woman was referred to our hospital because of abnormal shadows which had been increasing in size for 4 years, in the chest radiograph. Bronchoscopy revealed an endobronchial tumor at the orifice of the left B4b. Histological and immunohistological examination of the lesion showed tumor cells with immunoreactivity for thyroglobulin, and a metastatic oncocytic carcinoma from the thyroid was diagnosed. Closer examination of the neck revealed thyroid carcinoma, and total thyroidectomy was performed. Endobronchial metastasis of thyroid oncocytic carcinoma is very rare. In this case, immunohistological examination was useful for detecting the primary site.
authors.affiliation: Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, 3311-1 Yakushiji, Japan.
authors.forename: Akihisa
authors.initials: A
authors.lastname: Mitani
authors.forename: Naohiko
authors.initials: N
authors.lastname: Saku
authors.forename: Mitsugu
authors.initials: M
authors.lastname: Hironaka
authors.forename: Shoji
authors.initials: S
authors.lastname: Ohno
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Sohara
authors.forename: Ken
authors.initials: K
authors.lastname: Saito
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001984:Bronchial Neoplasms / Q000556:secondary*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000556:secondary*; D013954:Thyroglobulin / Q000276:immunology; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D001323:Autoantibodies; D014408:Biomarkers, Tumor; D013954:Thyroglobulin