title: [Two cases of systemic amyloidosis presenting with abnormalities in liver function tests].
abstract: Systemic amyloidosis results from the deposition of insoluble, fibrous amyloid proteins. It occurs mainly in the extracellular spaces of multiple organs and tissues including the kidney, heart, and liver. Although amyloid deposition in the liver is common in patients with systemic amyloidosis, clinically apparent liver disease is relatively rare. Indeed, most patients with systemic amyloidosis manifest only minimal to moderate hepatomegaly and trivial abnormalities in liver function tests. Recently, we experienced two cases of patients who presented with abnormalities in liver function tests and hepatomegaly as manifestations of systemic amyloidosis. We report these cases with a review of the relevant literatures.
authors.affiliation: Department of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea.
authors.forename: Jin Hyung
authors.initials: JH
authors.lastname: Park
authors.forename: Chang Kun
authors.initials: CK
authors.lastname: Park
authors.forename: Young Mi
authors.initials: YM
authors.lastname: Yun
authors.forename: Dong Woo
authors.initials: DW
authors.lastname: Hyun
authors.forename: Eun Soo
authors.initials: ES
authors.lastname: Kim
authors.forename: Soo Young
authors.initials: SY
authors.lastname: Park
authors.forename: Chang Min
authors.initials: CM
authors.lastname: Jo
authors.forename: Won Young
authors.initials: WY
authors.lastname: Tak
authors.forename: Young Oh
authors.initials: YO
authors.lastname: Kweon
authors.forename: Sung Kook
authors.initials: SK
authors.lastname: Kim
authors.forename: Yong Whan
authors.initials: YW
authors.lastname: Choi
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000473:pathology*; D005260:Female; D006529:Hepatomegaly / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged