[Experimental study on using mGTR and venous autografts to repair facial nerve defects in rabbits].
OBJECTIVE
To observe and compare the effects of using mGTR and venous autografts to repair the defect of facial nerve in rabbits.


METHODS
mGTR and venous autografts were performed on three groups of rabbits. Then physical and histological examinations were carried out to get the results of these two repair methods.


RESULTS
Both the two methods can induce regeneration of facial nerve. The mGTR is more effective and faster in repairing the nerve defect. Three months after operation, the distance of NCV between bilateral facial nerve in mGTR group was (2.10 +/- 1.2) m/s, (6.80 +/- 1.4) m/s in venous autografts, (2.16 +/- 1.6) m/s in nerve transplantation group. Histologically, the facial nerve fibers were arranged regularly and in continuity in mGTR, the facial nerve fibers were arranged irregularly with marked hyperplasia of connective tissues in venous autografts three months after repair.


CONCLUSIONS
The mGTR is more effective than venous autografts in repair of facial nerve.
Ma
Yue
Y
Dental College, Shandong University, Jinan 250012, Shandong, China.
Xu
Xin
X
Xin
Ning-ning
NN
Wang
Ji-tong
JT
Huang
Hai-yun
HY
D000818:Animals; D005154:Facial Nerve / Q000473:pathology / Q000601:surgery*; D005260:Female; D048091:Guided Tissue Regeneration / Q000379:methods*; D008297:Male; D009416:Nerve Regeneration; D011817:Rabbits; D014182:Transplantation, Autologous; D014680:Veins / Q000637:transplantation