Abortive potency of Chlamydophila abortus in pregnant mice is not directly correlated with placental and fetal colonization levels.
Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model. Expression of virulence of these strains varied and indicated that abortion was not directly related to the number of bacteria in the placenta, and thus, other factors may have an important role in activating the abortion process.
Bouakane
Amel
A
Unité de Recherche Pathologie Infectieuse et Immunologie, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France.
Benchaïeb
Ilhem
I
Rodolakis
Annie
A
D000034:Abortion, Veterinary; D000818:Animals; D023501:Chlamydophila / Q000472:pathogenicity*; D023521:Chlamydophila Infections / Q000382:microbiology*; D005260:Female; D005315:Fetal Diseases / Q000382:microbiology / Q000662:veterinary; D005333:Fetus / Q000382:microbiology*; D008098:Litter Size; D051379:Mice; D010920:Placenta / Q000382:microbiology*; D010922:Placenta Diseases / Q000382:microbiology / Q000662:veterinary; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology / Q000662:veterinary; D014774:Virulence