Perirhinal cortex relays auditory information to the frontal motor cortices in the rat.
Auditory evoked potentials (AEPs) were recorded in the motor cortices (MC) with chronically implanted electrodes in the rat. Some of the AEPs in the MC, namely negative potentials on the surface and positive ones at a depth of 2 mm at latencies of about 50-150 ms, were abolished by limited bilateral lesions of the anterior perirhinal cortex (PERa) which was responsive to auditory stimulus, indicating that the AEPs in the MC were at least partially relayed in the PERa. The auditory response in the MC was prominently enhanced when water was supplied or the medial forebrain bundle was stimulated after auditory stimulus. These results indicate that the MC receives the reward associated auditory information from the PERa.
Kyuhou
Shin-ichi
S
Department of Physiology, Kansai Medical University, Fumizono 10-15, Moriguchi, Osaka 570-8506, Japan. kyuho@takii.kmu.ac.jp
Matsuzaki
Ryuichi
R
Gemba
Hisae
H
D000161:Acoustic Stimulation; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001931:Brain Mapping; D003911:Dextrans / Q000378:metabolism; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology; D005260:Female; D009044:Motor Cortex / Q000033:anatomy & histology / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D051381:Rats; D011916:Rats, Inbred F344; D011930:Reaction Time; D012235:Rhodamines / Q000378:metabolism
D003911:Dextrans; C067661:Fluoro-Ruby; D012235:Rhodamines