Molecular epidemiology of orf513-bearing class 1 integrons in multiresistant clinical isolates from Argentinean hospitals.
The spread of orf513-bearing class 1 integrons is associated with bla(CTX-M-2) in gram-negative clinical isolates in Argentina, with In35 being the most frequently found integron (74%). Among 65 isolates without bla(CTX-M-2), only one harbored a novel orf513-bearing class 1 integron with the dfrA3b gene. The finding of orf513 not associated with class 1 integrons in two gram-positive strains indicates the widespread occurrence of this putative site-specific recombinase.
Arduino
Sonia M
SM
Facultad de Medicina de la Universidad de Buenos Aires, (1121) Capital Federal, Argentina. Sonia.Arduino@crchul.ulaval.ca
Catalano
Mariana
M
Orman
Betina E
BE
Roy
Paul H
PH
Centrón
Daniela
D
D001118:Argentina / Q000453:epidemiology; D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology; D001483:Base Sequence; D017931:DNA Primers; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D001618:beta-Lactamases / Q000235:genetics*
D017931:DNA Primers; C071167:beta-lactamase CTX-2; D001618:beta-Lactamases