title: Quinine intoxications reported to the Scottish Poisons Information Bureau 1997-2002: a continuing problem.
abstract: Quinine is widely prescribed in the UK for night cramps. Its potential toxicity in overdose is well known. We have reviewed the Scottish experience of enquiries regarding quinine overdose to the poisons information service responsible for Scotland over a 6-year period. Between 1997 and 2002 there were 96 reports of suspected quinine toxicity from Scotland (population 5.2 million), 19 of which were in children. The largest quantities of drug ingested were in patients between the ages of 11 and 30. In comparison with older studies the pattern of quinine poisoning does not appear to have changed in the UK over 20 years, despite recognition that it is a toxic agent in overdose, and particularly in children.
authors.affiliation: West Midlands Centre for Adverse Drug Reaction Reporting, City Hospital, Birmingham, UK. n.j.langford@bham.ac.uk
authors.forename: N J
authors.initials: NJ
authors.lastname: Langford
authors.forename: A M
authors.initials: AM
authors.lastname: Good
authors.forename: W J
authors.initials: WJ
authors.lastname: Laing
authors.forename: D N
authors.initials: DN
authors.lastname: Bateman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D062787:Drug Overdose / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000188:drug therapy / Q000453:epidemiology; D009125:Muscle Relaxants, Central / Q000506:poisoning*; D011803:Quinine / Q000506:poisoning*; D012606:Scotland / Q000453:epidemiology
chemical_list: D009125:Muscle Relaxants, Central; D011803:Quinine