title: Avian HSC emergence, migration, and commitment toward the T cell lineage.
abstract: To date three sites of emergence of hemopoietin cells have been identified during early avian development: the yolk sac, the intraaortic clusters and recently the allantois. However, the contributions of the hematopoietic stem cell (HSC) populations generated by these different sites to definitive hematopoiesis and their migration routes are not fully unraveled. Experimental embryology as well as the establishment of the genetic cascades involved in HSC emergence help now to draw a better scheme of these processes.
authors.affiliation: UMR CNRS 7622, Université Pierre et Marie Curie, 9, Quai St Bernard, 75005 Paris, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Jaffredo
authors.forename: Sandrine
authors.initials: S
authors.lastname: Alais
authors.forename: Karine
authors.initials: K
authors.lastname: Bollerot
authors.forename: Cecile
authors.initials: C
authors.lastname: Drevon
authors.forename: Rodolphe
authors.initials: R
authors.lastname: Gautier
authors.forename: Borhane
authors.initials: B
authors.lastname: Guezguez
authors.forename: Krisztina
authors.initials: K
authors.lastname: Minko
authors.forename: Pascale
authors.initials: P
authors.lastname: Vigneron
authors.forename: Dominique
authors.initials: D
authors.lastname: Dunon
mesh_terms: D000482:Allantois / Q000166:cytology; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology; D002642:Chick Embryo; D006410:Hematopoiesis / Q000502:physiology; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D011784:Quail / Q000196:embryology*; D013601:T-Lymphocytes / Q000166:cytology*; D015017:Yolk Sac / Q000166:cytology