A decade of caspases.
Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct functions of individual caspases and the mechanisms by which caspases mediate apoptosis and a variety of physiological and pathological processes.
Degterev
Alexei
A
Department of Cell Biology, Harvard Medical School, 240 Longwood Ave, Boston, MA 02115, USA.
Boyce
Michael
M
Yuan
Junying
J
D000494:Allosteric Regulation; D000818:Animals; D017209:Apoptosis; D020169:Caspases / Q000737:chemistry / Q000145:classification / Q000502:physiology*; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D015533:Transcriptional Activation
D004791:Enzyme Inhibitors; D020169:Caspases