Study of total lipid peroxidation and antioxidant activity in pulmonary and mediastinal malignant and benign tumor tissue.
Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of malignancy: the most pronounced changes were observed in thymoma and adenocarcinoma tissues and minimum changes were found in bronchoalveolar carcinoma tissue.
Korotkina
R N
RN
Clinical Biochemical Laboratory and Department of Thoracal Surgery, A. V. Vishnevskii Institute of Surgery, Russian Academy of Sciences, Moscow.
Spiridonova
O V
OV
Matskevich
G N
GN
Kucheinik
A Sh
ASh
Kunitsyn
A G
AG
Vishnevskii
A A
AA
Karelin
A A
AA
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology*; D001984:Bronchial Neoplasms / Q000473:pathology; D045744:Cell Line, Tumor; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology; D013945:Thymoma / Q000473:pathology
D000975:Antioxidants; D008054:Lipid Peroxides; D005979:Glutathione Peroxidase