title: Morphological study of reparative processes in the gingiva during therapy of chronic periodontitis with energostim and application of orthopedic splinting constructions.
abstract: We studied morphological characteristics of the regenerative process in gingival tissues during therapy of chronic periodontitis. Energostim stimulated macrophageal reaction and promoted neoangiogenesis in the inflammatory infiltrate. It was not observed after traditional drug therapy. Energostim promoted vascularization in regenerating tissues, normalized the structure at a greater area of the lamina propria of the gingiva, and prevented fibrous and sclerotic changes. The volume of histiolymphocytic infiltrates in regenerating gingival tissues decreased after application of intradental splints.
authors.affiliation: Krasnodar Research Center, Russian Academy of Medical Sciences, Krasnodar Krai Administration, Krasnodar.
authors.forename: L A
authors.initials: LA
authors.lastname: Faustov
authors.forename: V L
authors.initials: VL
authors.lastname: Popkov
authors.forename: P A
authors.initials: PA
authors.lastname: Galenko-Yaroshevskii
authors.forename: N L
authors.initials: NL
authors.lastname: Sycheva
authors.forename: V N
authors.initials: VN
authors.lastname: Meladze
mesh_terms: D002196:Capillaries / Q000378:metabolism; D002908:Chronic Disease; D045304:Cytochromes c / Q000494:pharmacology*; D004338:Drug Combinations; D004848:Epithelium / Q000378:metabolism; D005347:Fibroblasts / Q000378:metabolism; D005881:Gingiva / Q000098:blood supply / Q000473:pathology*; D005891:Gingivitis / Q000473:pathology*; D006801:Humans; D007249:Inflammation; D007288:Inosine / Q000494:pharmacology*; D008264:Macrophages / Q000378:metabolism / Q000473:pathology; D009092:Mucous Membrane / Q000473:pathology; D009243:NAD / Q000494:pharmacology*; D010518:Periodontitis / Q000188:drug therapy* / Q000378:metabolism; D013165:Splints; D013997:Time Factors; D014945:Wound Healing
chemical_list: D004338:Drug Combinations; C493512:energostim; D009243:NAD; D007288:Inosine; D045304:Cytochromes c