Solitary intracranial extra-osseous plasmacytoma presenting with ophthalmic signs.
Solitary plasmacytomas rarely develop in the skull, meninges, or brain. Ophthalmic signs as the initial manifestations of solitary intracranial plasmacytoma have rarely been described. We report the neuro-ophthalmologic, imaging, and pathologic findings for two patients. One patient presented with optic neuropathy, the second with bilateral sixth nerve palsies. Plasmacytoma is a treatable intracranial tumor that should be considered in the differential diagnosis of patients who present with optic neuropathy or sixth nerve palsy.
Brannan
Suzanne O
SO
Birmingham & Midland Eye Center, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QU, UK. suzanne@brannan43.fsnet.co.uk
Matthews
Bethan N
BN
Savant
Vijay
V
Brown
Ray D
RD
Matthews
Timothy D
TD
D020434:Abducens Nerve Diseases / Q000175:diagnosis* / Q000209:etiology; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000209:etiology; D010954:Plasmacytoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed