title: Noninvasive cardiac assessment in children of women with systemic lupus erythematosus.
abstract: OBJECTIVE
  Noninvasive cardiac assessment of newborns and infants of women with systemic lupus erythematosus. The children had no congenital total atrioventricular block and were compared with the children of healthy women.
  
  
  METHODS
  We prospectively assessed 13 newborns and infants aged 1 to 60 days, children of women with systemic lupus erythematosus and without congenital total atrioventricular block. These children were compared with 30 children of women who had no lupus or anti-Ro/SSA antibodies, and no risk factors for congenital heart disease either. Their age groups matched. The following examinations were performed: cardiological physical examination, electrocardiography, echocardiography, and signal-averaged electrocardiography.
  
  
  RESULTS
  The statistical analysis showed no significant difference in ventricular function or in the cardiac conduction system between the groups.
  
  
  CONCLUSIONS
  In regard to the conduction system and ventricular function in the absence of total atrioventricular block, no statistically significant difference was observed between the children of women with systemic lupus erythematosus and children of healthy women.
authors.affiliation: Hospital Universitário Pedro Ernesto, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Maria de Fátima
authors.initials: MF
authors.lastname: Monteitro Pereira Leite
authors.forename: Roger Aaron
authors.initials: RA
authors.lastname: Levy
authors.forename: Mônica Scott
authors.initials: MS
authors.lastname: Borges
authors.forename: Eduardo Correa
authors.initials: EC
authors.lastname: Barbosa
authors.forename: Paulo
authors.initials: P
authors.lastname: Ginefra
authors.forename: Paulo Roberto
authors.initials: PR
authors.lastname: Benchimol Barbosa
authors.forename: Paulo Roberto
authors.initials: PR
authors.lastname: Barbosa Benchimol
authors.forename: Nadia Barreto Tenório
authors.initials: NB
authors.lastname: Aoun
authors.forename: Luiz Alberto
authors.initials: LA
authors.lastname: Christiani
authors.forename: Francisco Manes
authors.initials: FM
authors.lastname: Albanesi Filho
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood; D016241:Child of Impaired Parents; D018618:Echocardiography, Doppler, Color; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000276:immunology; D006339:Heart Rate; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic; D008297:Male; D011446:Prospective Studies; D018709:Statistics, Nonparametric
chemical_list: D000974:Antibodies, Antinuclear; C035356:SS-A antibodies