X-linked Charcot-Marie-Tooth disease with myokymia: report of a family.
The clinical and electrophysiologic profiles of two brothers suffering from Charcot-Marie-Tooth disease are presented. Both had widespread muscle twitching in the legs which showed electrophysiologic features of myokymia. Pedigree analysis suggested an x-linked recessive form of inheritance. This appears to be the first report of an Indian family with x-linked Charcot-Marie-Tooth disease.
Chakravarty
A
A
Vivekananda Institute of Medical Sciences and B. R. Singh Hospital and Research Center, Calcutta, India. saschakra@yahoo.com
Ghosh
B
B
Sengupta
S
S
Mukhopadhyay
S
S
D000293:Adolescent; D002607:Charcot-Marie-Tooth Disease / Q000175:diagnosis / Q000235:genetics*; D041321:Chromosomes, Human, X; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D020385:Myokymia / Q000175:diagnosis / Q000235:genetics*; D010375:Pedigree