title: Successful treatment of childhood spasticity secondary to cerebral palsy using Botox.
abstract: Spasticity resulting from cerebral palsy can reduce the quality of life in affected children and can eventually cause more severe impairments, such as joint dislocation and scoliosis. Botulinum toxin type A (Botox) is widely used to temporarily alleviate the increased muscle tone associated with spasticity, and when combined with a comprehensive physical therapy regimen can result in permanent improvement. This report documents the successful use of Botox over a two-year period to treat spasticity secondary to cerebral palsy in a preschool-age child. Botox was used in conjunction with a specific physical therapy regimen in order to reach a functional goal of independent ambulation.
authors.affiliation: Department of Neurology, Vanderbilt University Medical Center, Suite 304, Medical Center South, Nashville, TN 37212, USA.
authors.forename: Chandler
authors.initials: C
authors.lastname: Gill
authors.forename: Cassondra
authors.initials: C
authors.lastname: Covington
authors.forename: Bimal
authors.initials: B
authors.lastname: Padaliya
authors.forename: William
authors.initials: W
authors.lastname: Newman
authors.forename: Terri
authors.initials: T
authors.lastname: Pomeroy
authors.forename: P David
authors.initials: PD
authors.lastname: Charles
mesh_terms: D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000150:complications*; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009128:Muscle Spasticity / Q000188:drug therapy / Q000209:etiology; D009465:Neuromuscular Agents / Q000627:therapeutic use*
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A