Kinetics of anaerobic metabolism in human skeletal muscle: influence of repetitive high-intensity exercise on sedentary dominant and non-dominant forearm. A 31P NMR study.
Potential differences were assessed between the dominant (D) and non-dominant (ND) forearms of sedentary subjects during anaerobic exercise. Subjects performed voluntary concentric contractions of D and ND forearm muscle during a series of three high-intensity (60% of the maximal voluntary contraction force (MVC)) exercise bouts. The time-dependent changes in intracellular pH (pH(i)), Pi, and PCr concentrations, and their relation to muscular work were examined using 31P magnetic resonance spectroscopy (MRS) techniques, and revealed that D forearm metabolic kinetics in sedentary individuals are improved during repetitive high-intensity exercise compared to their respective ND forearm muscle. We postulate that the more regular and preferential utilization of the D limb leads to a "trained-like" condition.
Brosseau
Olivier E F
OE
UMR 5012 CNRS, Domaine Scientifique de la Doua, CPE, 3, rue Victor-Grignard, 69616 Villeurbanne, France. olivier.brosseau@univ-lyon1.fr
Mahdjoub
Rachid
R
Seurin
Marie José
MJ
Thiriet
Patrice
P
Gozal
David
D
Briguet
André
A
D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology*; D004734:Energy Metabolism; D015444:Exercise; D005542:Forearm / Q000098:blood supply / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008279:Magnetic Resonance Imaging; D008297:Male; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000098:blood supply / Q000378:metabolism*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D010759:Phosphorus Isotopes
D010710:Phosphates; D010759:Phosphorus Isotopes; D010725:Phosphocreatine