title: Imaging in appendicitis: a review with special emphasis on the treatment of women.
abstract: OBJECTIVE
  Acute abdominal pain in women often presents the clinician with a diagnostic dilemma, especially if it is lower abdominal pain. Appendicitis is frequently entertained as a diagnosis, but until recently, the gold standard diagnostic procedure was operation, carrying a high false-negative rate. In recent years, computed tomographic (CT) scan has been advocated as a diagnostic aid. The purpose of this systematic review was to evaluate the accuracy of CT scan in diagnosing appendicitis.
  
  
  METHODS
  Investigators searched PubMed between January and July 2003 using the terms "CT scan" and "appendicitis" with the limits "All adults 19+ years" and "English [language]." In addition, reference lists of all obtained articles were reviewed for other potential citations.
  
  
  METHODS
  All prospective studies of adults published in English were considered.
  
  
  RESULTS
  Initial searches and reviews yielded 248 citations. Twenty-three of the citations reported prospective studies; only two of these were randomized studies. Prospective studies report sensitivities ranging from 77% to 100%, specificities ranging from 83% to 100%, and accuracies ranging from 88% to 98% for the diagnosis of acute appendicitis. Information gained from CT scans in patients with suspected appendicitis results in alternative diagnosis in 6% to 36%. These values are similar for both men and women.
  
  
  CONCLUSIONS
  The data support routine use of CT scan in both men and women for the diagnosis of appendicitis.
authors.affiliation: Department of Surgery, Salt Lake City VA Healthcare System, and the University of Utah, 84132, USA. leigh.neumayer@hsc.utah.edu
authors.forename: Leigh
authors.initials: L
authors.lastname: Neumayer
authors.forename: Anne
authors.initials: A
authors.lastname: Kennedy
mesh_terms: D001064:Appendicitis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011446:Prospective Studies; D012737:Sex Factors; D014057:Tomography, X-Ray Computed