title: Magnetic resonance imaging of the cervical spine: frequency of degenerative changes in the intervertebral disc with relation to age.
abstract: OBJECTIVE
  To ascertain the level at which intervertebral disc degeneration of the cervical spine most commonly occurs in each decade from 20-79 years.
  
  
  METHODS
  Using computer analysis, we retrospectively assessed the mean signal intensity from each cervical disc from T2-weighted spin-echo images in 60 symptomatic patients (10 per decade from the third to eighth inclusive).
  
  
  RESULTS
  Age, disc level and interaction between age and level were highly significant predictors for the magnetic resonance imaging (MRI) mean signal intensity from intervertebral discs (p<0.0001 for all three terms). The MRI signals were generally lower as age increased and also for the higher discs (C2-C3, etc).
  
  
  CONCLUSIONS
  In our study we have shown that in younger patients the higher discs are more frequently affected by degeneration than the lower ones. As age increases, the process of degeneration becomes more generalized with less variability between discs.
authors.affiliation: Radiology Department, Leicester Royal Infirmary, Leicester, UK.
authors.forename: J A
authors.initials: JA
authors.lastname: Abdulkarim
authors.forename: R
authors.initials: R
authors.lastname: Dhingsa
authors.forename: D B
authors.initials: DB
authors.lastname: L  Finlay
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002574:Cervical Vertebrae / Q000473:pathology*; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D019547:Neck Pain / Q000209:etiology; D010292:Paresthesia / Q000209:etiology; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000175:diagnosis*