Clostridium perfringens type A myonecrosis in a horse in Korea.
Acute hemorrhagic myonecrosis accompanied by severe inter- and intrafascicular edema and hemorrhage of the right gluteal area was diagnosed in a 13-year-old male thoroughbred horse. Once the muscular and fascicular changes were subsided, the horse then developed acute respiratory problem. Histologically, the lung had diffuse severe hemorrhage with mild neutrophilic infiltration. The cause of death was acute respiratory failure that is believed to occur secondary to toxaemic event. Alpha and beta2 toxin secreting Clostiridum perfringens type A was isolated from the muscle and lung. The diagnosis was based on the light microscopic examination, bacterial toxinotyping and toxin genotyping from the muscular and pulmonary lesion. Also, susceptibility of the isolates to antimicrobial agents was determined.
Choi
Yang-Kyu
YK
Korea Research Institute of Bioscience and Biotechnology, Taejon, Korea.
Kang
Min-Soo
MS
Yoo
Han-Sang
HS
Lee
Deog-Yong
DY
Lee
Hyun-Chul
HC
Kim
Dae-Yong
DY
D000818:Animals; D001427:Bacterial Toxins; D003015:Clostridium Infections / Q000473:pathology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000502:physiology*; D004586:Electrophoresis; D004768:Enterotoxins; D017809:Fatal Outcome; D006652:Histological Techniques; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology*; D006736:Horses; D007723:Korea; D008168:Lung / Q000473:pathology; D008297:Male; D009135:Muscular Diseases / Q000473:pathology / Q000662:veterinary*; D009336:Necrosis
D001427:Bacterial Toxins; D004768:Enterotoxins; C109896:cpb2 protein, Clostridium perfringens; C035598:enterotoxin, Clostridium