title: A retrospective comparison of inpatients with mixed and pure depression.
abstract: Some authors advocate a broadening of the narrow concept of mixed episodes in the direction of mania leading to the concept of mixed mania, and in the direction of depression leading to the concept of mixed depression. The latter has been little investigated so far. In the present article, we retrospectively compare 49 patients with pure depression with 51 patients with mixed depression in terms of socio-demographic and clinical variables in order to contribute to the validation of the distinction between mixed and pure depression. Supporting this distinction, we observed that mixed depressive patients more frequently had past histories of bipolar disorder and alcohol abuse and had longer durations of hospital stay. These last two points remain significant even when we control for the effect of the association with bipolarity.
authors.affiliation: Clinic of Adult Psychiatry, Department of Psychiatry, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Séverine
authors.initials: S
authors.lastname: Ducrey
authors.forename: Marianne
authors.initials: M
authors.lastname: Gex-Fabry
authors.forename: Alexandre
authors.initials: A
authors.lastname: Dayer
authors.forename: Emna Ragama
authors.initials: ER
authors.lastname: Pardos
authors.forename: Loraine
authors.initials: L
authors.lastname: Roth
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Aubry
authors.forename: Gilles
authors.initials: G
authors.lastname: Bertschy
mesh_terms: D000328:Adult; D000368:Aged; D003863:Depression / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation*; D005260:Female; D006760:Hospitalization; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index