Injectable polydimethylsiloxane-hydroxyapatite composite cement.
An injectable polydimethylsiloxane/hydroxyapatite (PDMS/HAp) composite cement was synthesised using linear PDMS and HAp (particles of about 100 nm in size) of different mass fractions. The effect of HAp mass fraction (5-60 mass%) on the hardness of PDMS/HAp composite cement was investigated. The hardness achieved is 25-49 degrees ShA. Differential scanning calorimetry (DSC) was used to study the cross-linking process and the influence of HAp on the temperature and duration of PDMS/HAp cross-linking. The microstructure of composite cement surfaces after 10 days in vivo tests was observed by scanning electron microscopy (SEM). The presence of well-adhered macrophages, fibroblasts and monocytes was found on the implant surface upon its extraction from the organism.
Ignjatović
Nenad
N
Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, Knez Mihailova 35/IV, 11000 Belgrade, Serbia and Montenegro.
Jovanović
Jelena
J
Suljovrujić
Edin
E
Uskoković
Dragan
D
D000818:Animals; D001843:Bone Cements / Q000138:chemical synthesis / Q000737:chemistry*; D002448:Cell Adhesion / Q000502:physiology; D003188:Composite Resins / Q000138:chemical synthesis / Q000737:chemistry*; D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D005347:Fibroblasts / Q000502:physiology* / Q000648:ultrastructure*; D006244:Hardness; D007267:Injections / Q000295:instrumentation / Q000379:methods; D008420:Manufactured Materials; D008422:Materials Testing; D051379:Mice; D008968:Molecular Conformation; D012828:Silicones / Q000737:chemistry*; D013696:Temperature
D001843:Bone Cements; D003188:Composite Resins; D004129:Dimethylpolysiloxanes; D012828:Silicones; C013830:baysilon; D017886:Durapatite