title: Macular hole closure after peribulbar steroid injection.
abstract: OBJECTIVE
  To report the closure of a macular hole after a peribulbar corticosteroid injection in a patient with anterior uveitis associated with human leukocyte antigen B*27.
  
  
  METHODS
  Interventional case report.The patient was evaluated by comprehensive ophthalmic check-up and optical coherence tomography.
  
  
  RESULTS
  A healthy 50-year-old woman presented to our service with active human leukocyte antigen B*27-associated anterior uveitis, macular hole in the right eye and macular edema in the left eye. Visual acuity was 20/200 in both eyes. Peribulbar injections of triamcinolone acetonide were administered in both eyes. Three months later, visual acuity improved to 20/50 in both eyes, and the uveitis was in complete remission. Optical coherence tomography verified that the macular hole in the right eye was closed.
  
  
  CONCLUSIONS
  Inflammation and macular edema might be contributing factors in macular hole formation in patients with uveitis. This case indicates that treatment of inflammation and macular edema might lead to macular hole closure in similar cases.
authors.affiliation: Department of Ophthalmology, General Hospital of Athens, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Halkiadakis
authors.forename: Eugenia
authors.initials: E
authors.lastname: Pantelia
authors.forename: Nikos
authors.initials: N
authors.lastname: Giannakopoulos
authors.forename: Chrisanthi
authors.initials: C
authors.lastname: Koutsandrea
authors.forename: Nikos N
authors.initials: NN
authors.lastname: Markomichelakis
mesh_terms: D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D015796:HLA-B27 Antigen / Q000276:immunology; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D009915:Orbit; D012167:Retinal Perforations / Q000188:drug therapy* / Q000209:etiology; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014606:Uveitis, Anterior / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D015796:HLA-B27 Antigen; D014222:Triamcinolone Acetonide