title: [Inflammation in peritoneal dialysis].
abstract: In patients on peritoneal dialysis, peritoneal membrane alterations with inadequate peritoneal membrane function may be induced during long-term therapy. Chronic inflammation triggers malnutrition and atherosclerotic cardiovascular disease contributing to high mortality. The role of catheter, peritonitis and peritoneal dialysis fluids is argued. A neutral pH, a lesser presence of glucose degradation products generated during heat sterilization and accelerating the production of advanced glycosylation end-products (AGEs) could be reduced with better biocompatibility of peritoneal dialysis fluids.
authors.affiliation: Service de néphrologie, dialyse et transplantation rénale, Centre hospitalier universitaire de Caen. ryckelynck-jp@chu-caen.fr
authors.forename: J Ph
authors.initials: JP
authors.lastname: Ryckelynck
authors.forename: Th
authors.initials: T
authors.lastname: Lobbedez
authors.forename: M
authors.initials: M
authors.lastname: Pujo
authors.forename: W
authors.initials: W
authors.lastname: el Haggan
authors.forename: B
authors.initials: B
authors.lastname: Hurault de Ligny
mesh_terms: D015415:Biomarkers / Q000097:blood; D002408:Catheters, Indwelling / Q000009:adverse effects; D015314:Dialysis Solutions / Q000494:pharmacology; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000209:etiology*; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000150:complications / Q000209:etiology; D010968:Plasticizers / Q000009:adverse effects
chemical_list: D015415:Biomarkers; D015314:Dialysis Solutions; D010968:Plasticizers