[Epidemiologic study of admitted children with Kawasaki disease in Beijing from 1995 to 1999].
OBJECTIVE
To evaluate the epidemiologic picture of Kawasaki disease (KD) in Beijing and its suburbs.


METHODS
A questionnaire form and diagnostic guideline for KD were sent to all hospitals with pediatric inpatient beds throughout Beijing and its suburbs. Pediatricians were asked to review the medical records and report all patients with KD diagnosed during the 5-year period from January, 1995, to December, 1999.


RESULTS
A total of 710 patients with KD were reported from 37 (95%) of 39 hospitals with pediatric inpatient beds. The incidence rates of KD were 18.2 (1995), 21.1 (1996), 18.6 (1997), 30.6 (1998) and 27.8 (1999) per 100,000 children < 5 years of age. The male:female ratio was 1.7:1. The age at onset ranged from 1 month to 13.4 years (with median of 2.3 years), with 85.2% < 5 years old. The disease occurred more frequently in spring and summer and less frequently in autumn and early winter. Lymph node enlargement was the least common clinical sign, and its incidence decreased from 1995 to 1999. Cardiac abnormalities were found in 21.5% of patients and were more prevalent in patients diagnosed 10 days or longer after the onset. No patients died in the acute stage.


CONCLUSIONS
The incidence of KD in Beijing is lower than that reported in Japan, similar to the incidence in the United States and higher than in those other Western countries. The age and gender distribution and increasing trend in incidence are similar to those in previous reports, but seasonal distribution is unique.
Du
Zhong-dong
ZD
Beijing Children's Hospital, Capital Institute of Pediatrics, Peking Universiy, Beijing 100045, China.
Liang
Lu
L
Meng
Xiao-ping
XP
Li
Tang
T
Zhang
Tuo-hong
TH
Kawasaki
T
T
Yanagawa
H
H
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology*; D012737:Sex Factors; D013997:Time Factors