Switching by pulse electric field of the elevated enzymatic reaction in the core of polyion complex micelles.
Polyion complex micelles entrapping enzyme molecules in the core provide a unique reaction field inducing a remarkable elevation of enzymatic reactivity through a drastic change in the binding specificity between the enzyme and substrate. On-off switching of this enhanced effect was achieved through the destabilization of the core domain by applying a pulse electric field.
Harada
Atsushi
A
Department of Applied Materials Science, Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, Sakai, Osaka 599-8531, Japan.
Kataoka
Kazunori
K
D003124:Colorimetry / Q000379:methods; D004527:Egg Proteins / Q000737:chemistry; D007700:Kinetics; D008823:Micelles; D009113:Muramidase / Q000737:chemistry* / Q000378:metabolism; D009844:Oligosaccharides / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry
D004527:Egg Proteins; D008823:Micelles; D009844:Oligosaccharides; D010455:Peptides; C017645:polyaspartate; D011092:Polyethylene Glycols; D009113:Muramidase