Successful pregnancy outcome following 19 consecutive miscarriages: case report.
No cause can be found in 50% of patients with recurrent miscarriage. Recent research has shown that high levels of natural killer (NK) cells within the endometrium may be associated with idiopathic recurrent miscarriage. This case report describes a patient in whom an excessive number of uterine NK cells were found. She received preconceptual prednisolone and delivered a live baby. This is a novel observation of untested significance.
Quenby
Siobhan
S
Departments of Obstetrics and Gynaecology and Immunology, University of Liverpool, Liverpool L69 3BX, UK. squenby@liv.ac.uk
Farquharson
Roy
R
Young
Michelle
M
Vince
Gill
G
D000026:Abortion, Habitual / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology; D002452:Cell Count; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000473:pathology
D011239:Prednisolone