title: Three-dimensional conformal radiation therapy (3D-CRT) for early-stage non-small-cell lung cancer.
abstract: The standard treatment for early-stage non-small-cell lung cancer is surgical resection. However, many patients are inoperable due to medical comorbidities. Thirty-two medically inoperable patients with early-stage non-small-cell lung cancer were treated with 3-dimensional conformal radiation therapy between January 1991 and December 2000. The median dose was 70.2 Gy, and the median follow-up time in survivors was 30 months. The 2-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 54%, and 57%, respectively. The 5-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 33%, and 39%, respectively. This report suggests that local control is improved with high-dose conformal radiation therapy when compared to other institutions' retrospective experiences.
authors.affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. rosenzwk@mskcc.org
authors.forename: K E
authors.initials: KE
authors.lastname: Rosenzweig
authors.forename: N
authors.initials: N
authors.lastname: Dladla
authors.forename: R
authors.initials: R
authors.lastname: Schindelheim
authors.forename: S E
authors.initials: SE
authors.lastname: Sim
authors.forename: L E
authors.initials: LE
authors.lastname: Braban
authors.forename: E S
authors.initials: ES
authors.lastname: Venkataraman
authors.forename: S A
authors.initials: SA
authors.lastname: Leibel