title: Nevoid basal cell carcinoma syndrome: report of an aggressive case with ethmoid sinus invasion.
abstract: Nevoid basal cell carcinoma syndrome, also referred to as Gorlin-Goltz syndrome, is a rare autosomal dominant disorder characterized by multiple basal cell carcinomas, jaw cysts, palmar or plantar pits, ectopic calcification of the falx cerebri, and various skeletal developmental abnormalities. A minority of basal cell carcinomas demonstrate aggressive behavior and involve the craniofacial bones in nevoid basal cell carcinoma syndrome. A non-familial case of nevoid basal cell carcinoma syndrome with a basal cell carcinoma of the eyelid invading to the ethmoid sinus is reported.
authors.affiliation: Department of Otolaryngology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, 305-8575, Tsukuba, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Tabuchi
authors.forename: Hideki
authors.initials: H
authors.lastname: Okubo
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Takahashi
authors.forename: Isao
authors.initials: I
authors.lastname: Uemaetomari
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shimoyamada
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Nakayama
authors.forename: Akira
authors.initials: A
authors.lastname: Hara
mesh_terms: D000368:Aged; D001478:Basal Cell Nevus Syndrome / Q000235:genetics / Q000473:pathology*; D005005:Ethmoid Sinus / Q000473:pathology*; D005142:Eyelid Neoplasms / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000235:genetics / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000235:genetics / Q000473:pathology*; D010375:Pedigree; D014057:Tomography, X-Ray Computed