Subeschar clysis in deep burns.
Six hundred thirteen patients with deep burn of up to 50% total body surface area (TBSA) were treated with 0.25% povidone iodine subeschar clysis (PVP-SEC) in addition to surface application of povidone iodine + Neosporin in the form of "crust". The results were compared with those of 595 age, sex and percentage of burn, matched patients treated only by "crust application". The quantitative bacterial count showed significantly less incidence of infection on the 7th and 8th days post treatment (P<0.001). The organisms identified were predominately Staphylcocous aureus and Pseudomonas aeroginosa. Significantly more number of patients, with burns up to 50% TBSA, could be grafted within 20 days in the SEC group. The graft acceptance rate in this group was 90%.
Sinha
Rajeev
R
Department of Surgery and Microbiology, M.L.B. Medical College, 284128, U.P., Jhansi, India. singharga@yahoo.com
Sharma
Neeta
N
Agarwal
R K
RK
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D001414:Bacitracin / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D002056:Burns / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D009355:Neomycin / Q000627:therapeutic use*; D011112:Polymyxin B / Q000627:therapeutic use*; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000627:therapeutic use; D016038:Skin Transplantation; D016896:Treatment Outcome
D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D001414:Bacitracin; C001816:bacitracin zinc, neomycin sulfate, polymyxin B, drug combination; D011206:Povidone-Iodine; D009355:Neomycin; D011112:Polymyxin B