[Intraosseous neurilemmoma of the jaw: report of 11 consecutive cases].
OBJECTIVE
This study retrospectively analyzed the clinical data of 11 patients with intraosseous neurilemmoma of the jaw, with the purpose of improve its diagnosis and treatment.


METHODS
11 patients with intraosseous neurilemmoma of the jaw treated from January 1993 to February 2002 were reviewed, including the clinical features, pathological findings, immunohistochemical findings, imaging examinations and treatment methods. 8 patients with benign lesions were treated with radical curettage and cautery. 2 patients with mandibular malignant lesions were treated with extended resection and neck dissection. 1 patient with maxillary malignant lesion concomitant with neurofibrostosis was treated with extensive resection and middle split skin graft and neck dissection, followed by chemotherapy and radiotherapy after surgery.


RESULTS
The lesions were located in the maxilla in 5 patients (1 was malignant). 6 patients had mandibular lesions (2 were malignant). The X ray findings had some specificity. 10 patients were followed up for 7 to 122 months without recurrence. 1 patient with maxillary malignant lesion died of multiple metastasis 11 months after treatment.


CONCLUSIONS
Intraosseous neurilemmoma of the jaw was rarely seen clinically. CT, MRI and fine needle aspiration biopsy were beneficial for early diagnosis. Surgery is still the dominant choice of treatment. The prognosis of the patients was generally good. Adjuvant radiotherapy or chemotherapy had limited value, especially for patients with neurofibrostosis. A novel regime called CYVADICDE was recently invoked much clinical interest.
Zhao
Ji-mou
JM
Department of Dentistry, People's Hospital of Penglai City, Shandong, Penglai 265600, China. zhaojimou@163.com
Xu
Bing
B
Zheng
Jia-wei
JW
Tang
You-sheng
YS
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007573:Jaw Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014057:Tomography, X-Ray Computed