[A new group of potential antitubercular agents: antimycobacterial N-benzylsalicylamides].
Linking up with a previous study of antimycobacterial compounds, several groups of N-benzylsalicylamides were prepared and their antimycobacterial activities against the strains Mycobacterium tuberculosis, Mycobacterium kansasii, and Mycobacterium avium were evaluated. The obtained data were analyzed by Free-Wilson method in comparison with their isosteric analogues of 3-hydroxypicolinic and 2-sulfanylbenzoic acids described in the previous communication.
Waisser
K
K
Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové. waisser@faf.cuni.cz
Perina
M
M
Boudová
I
I
Kunes
J
J
Kaustová
J
J
D000995:Antitubercular Agents / Q000737:chemistry; D006801:Humans; D012457:Salicylamides / Q000737:chemistry
D000995:Antitubercular Agents; D012457:Salicylamides