[Study of nausea and vomiting accompanying intravenous patient-controlled analgesia with fentanyl after cervical spine surgery].
BACKGROUND
Serious side effects of postoperative analgesia with opioid drugs include nausea and vomiting.


METHODS
We investigated the effects of various factors (patient background, anesthesia duration, and intraoperative drug use) on the frequency and degree of postoperative nausea and vomiting (PONV) during the first 24 hours of intravenous patient-controlled analgesia (PCA) with fentanyl.


RESULTS
PONV occurred in 34% of the male patients and 68% of the female, and in 31% and 58% of smokers and non-smokers, respectively.


CONCLUSIONS
Consideration should be given to gender and smoking status prior to starting preventive antiemetic therapy using PCA with fentanyl following cervical spine surgery.
Okamura
Kenta
K
Department of Anesthesia and Intensive Care, Hiroshima City Asa Hospital, Hiroshima 730-0293.
Sanuki
Michiyoshi
M
Kinoshita
Hiroyuki
H
Fujii
Kiyoshi
K
Matsunaga
Aki
A
D000368:Aged; D000375:Aging; D016058:Analgesia, Patient-Controlled / Q000009:adverse effects*; D000932:Antiemetics / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000601:surgery*; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking
D000932:Antiemetics; D005283:Fentanyl