[Clinical value comparison between chemiluminescent immunoassay and immunoradiometric assay in detecting TSH in serum].
OBJECTIVE
To compare the clinical value between chemiluminescent immunoassay (CLIA) and immunoradiometric assay (IRMA) in detecting TSH in patients with hyperthyroidism and hypothyroidism.


METHODS
The TSH levels in serums were detected by CLIA and IRMA in 112 normal persons, 120 hyperthyroidism patients and 58 hypothyroidism patients.


RESULTS
CLIA was significantly correlated with IRMA (r = 0.98, P < 0.01). CLIA had higher coincidence rate than IRMA in the diagnosis of hyperthyroidism and hypothyroidism, and CLIA was more accurate and repetitive than IRMA.


CONCLUSIONS
CLIA is more valuable than IRMA in diagnosing both hyperthyroidism and hypothyroidism.
Yu
Jian-ying
JY
Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Lin
Ying
Y
D000328:Adult; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood* / Q000175:diagnosis; D007037:Hypothyroidism / Q000097:blood* / Q000175:diagnosis; D007118:Immunoassay / Q000379:methods; D015592:Immunoradiometric Assay; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013972:Thyrotropin / Q000097:blood*
D013972:Thyrotropin