title: Cloning and sequencing of Duck circovirus (DuCV).
abstract: The genome of Duck circovirus (DuCV) is circular and 1996 nts in size. Two major open reading frames were identified, encoding the replicase (V1) and the capsid protein (C1). A stem-loop structure comprising the nonamer 5'-TATTATTAC, conserved in all circo-, nano- and geminiviruses, was found. Unique to DuCV, the region between the 3'-ends of the rep and cap gene contains four repeats of a 44-bp sequence. Phylogenetic analysis shows close relation of DuCV with Goose circovirus and suggests classification of DuCV as a new member of the genus Circovirus of the virus family Circoviridae.
authors.affiliation: P11 Neue Viren/Xenotranplantation, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Hattermann
authors.forename: C
authors.initials: C
authors.lastname: Schmitt
authors.forename: D
authors.initials: D
authors.lastname: Soike
authors.forename: A
authors.initials: A
authors.lastname: Mankertz
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D017925:Circovirus / Q000145:classification / Q000235:genetics*; D003001:Cloning, Molecular; D004372:Ducks / Q000821:virology*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny