title: Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms.
abstract: A method for automatic volume segmentation of functional imaging based on a relationship between source-to-background ratio and the iso-activity level to be used is described. Such method, which has been established with radioactive spheres in a phantom, is independent of the a priori knowledge of the lesion of interest and is valid for small (>2 ml) and/or poorly contrasted (S/B>1.5) lesions. Accuracy varies slightly with the image reconstruction algorithm used.
authors.affiliation: Department of Radiation Oncology, Laboratory of Radiobiology, Université catholique de Louvain, St-Luc University Hospital, 10 Ave Hippocrate, B-1200 Brussels, Belgium.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Daisne
authors.forename: Mérence
authors.initials: M
authors.lastname: Sibomana
authors.forename: Anne
authors.initials: A
authors.lastname: Bol
authors.forename: Thomas
authors.initials: T
authors.lastname: Doumont
authors.forename: Max
authors.initials: M
authors.lastname: Lonneux
authors.forename: Vincent
authors.initials: V
authors.lastname: Grégoire
mesh_terms: D000465:Algorithms; D019047:Phantoms, Imaging; D014055:Tomography, Emission-Computed / Q000379:methods*