Role of the natriuretic peptide system in cardiorenal protection.
Significant progress has been made in the understanding of the neurohormonal factors that contribute to the progression of chronic renal and cardiac failure and the development of target-organ damage in patients with hypertension and diabetes. We herein review some of these advances, including a new therapeutic strategy for potentially enhancing cardiorenal protection in patients with these disorders.
McFarlane
Samy I
SI
Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, State University of New York Health Science Center at Brooklyn, 11203, USA.
Winer
Nathaniel
N
Sowers
James R
JR
D000818:Animals; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy* / Q000503:physiopathology*; D045265:Natriuretic Peptides / Q000502:physiology*; D011480:Protease Inhibitors / Q000627:therapeutic use*
D045265:Natriuretic Peptides; D011480:Protease Inhibitors