title: Significance of complications of allergic diseases in young patients with interstitial cystitis.
abstract: BACKGROUND
  It was found that about one-half of interstitial cystitis (IC) patients have complications of allergic diseases. However, significance of the complications have not been studied.
  
  
  METHODS
  Thirty-four patients (age range 20 to 39 years old) meeting the diagnostic criteria of NIDDK established in 1987 were selected. Clinical allergic tests and significance of complications of allergic diseases were examined.
  
  
  RESULTS
  Eighty-six percent of young patients had complications of allergic diseases. In two patients, IC was a part of generalized allergic diseases. In 25 patients, IC was suggested to have some association with allergy. Of these 25 patients, there were alternating symptoms or proportionally changing symptoms of allergy and IC in 15 patients, and the number of eosinophils increased in six patients. Seven IC patients were considered to have developed allergic diseases only by chance without apparent association.
  
  
  CONCLUSIONS
  Complications of allergic diseases are frequent, particularly in young IC patients. The results suggest the involvement of allergy in about 80% of IC patients with complications of allergic diseases. In only 6% of patients, IC was a part of generalized allergic disease.
authors.affiliation: Department of Urology, National Sagamihara Hospital, Sagamihara city, Kanagawa, Japan. t-yamada@sagamihara-hosp.gr.jp
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Yamada
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D018856:Cystitis, Interstitial / Q000150:complications*; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D008875:Middle Aged