title: Role of radiology in the treatment of malignant hilar biliary strictures 2: 10 years of single-institution experience with percutaneous treatment.
abstract: We reviewed the results of percutaneous intervention of hilar biliary malignancy over a 10-year period at a single institution: the Royal Melbourne Hospital. Ninety-nine patients (100 treated in total) were included. Information was retrieved by retrospective examination of patient notes and radiology, combined with interviews with family and relevant physicians. Sixty-nine patients were treated with insertion of semipermanent stents, 19 had external drain tubes, and 25 received percutaneous access for Iridium brachytherapy. Adequate drainage was achieved in 87% of the patients stented, and percutaneous access was successful in 96% of patients planned for brachytherapy. Of those patients undergoing endoprosthesis insertion, early complications occurred in 39% and late complications in 23%. Average survival for the entire patient population was 227.3 days, with a median of 167 days. Longer survival times (213 vs 142 days) and lower complication rates (44 vs 64%) are observed with metal stents in comparison with plastic stents. Percutaneous intervention is an important treatment option in hilar biliary malignancy, particularly in patients unfit for surgery. Reasonable survival with good palliation is the most common outcome, and most patients do not require further intervention.
authors.affiliation: St Vincent's Hospital, Melbourne, Australia. mickhii@hotmail.com
authors.forename: Michael W J
authors.initials: MW
authors.lastname: Hii
authors.forename: Robert N
authors.initials: RN
authors.lastname: Gibson
authors.forename: Anthony G
authors.initials: AG
authors.lastname: Speer
authors.forename: Neil A
authors.initials: NA
authors.lastname: Collier
authors.forename: Noel
authors.initials: N
authors.lastname: Sherson
authors.forename: Cate
authors.initials: C
authors.lastname: Jardine
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications / Q000532:radiotherapy*; D001653:Bile Ducts, Intrahepatic; D016009:Chi-Square Distribution; D018281:Cholangiocarcinoma / Q000150:complications / Q000532:radiotherapy*; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications / Q000532:radiotherapy*; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome