Retention time reproducibility in comprehensive two-dimensional gas chromatography using cryogenic modulation. II. An interlaboratory study.
An interlaboratory survey was conducted to determine the reproducibility of retention times in both the first (1D) and second dimension (2D) axes of the two-dimensional separation space, using the longitudinal cryogenic modulation comprehensive two-dimensional gas chromatographic approach. Intralaboratory reproducibility has been demonstrated in part 1 of this investigation [J. Chromatogr. A 968 (2002) 161]. Confidence in absolute retention times (hence component positions) in the two-dimensional separation space is critical to component identification. Comparing data from four independent laboratories, five independent gas chromatographs, five independent LMCS units, and numerous operators has determined that the LMCS cryogenic modulation approach provides reliable comprehensive two-dimensional GC results.
Shellie
Robert
R
Australian Centre for Research on Separation Science, Department of Applied Chemistry, RMIT University, G.P.O. Box 2476V, Melbourne, Victoria 3001, Australia.
Marriott
Philip
P
Leus
Michelle
M
Dufour
Jean-Pierre
JP
Mondello
Luigi
L
Dugo
Giovanni
G
Sund
Kefu
K
Winniford
Bill
B
Griffith
James
J
Luong
Jim
J
D002849:Chromatography, Gas / Q000379:methods*; D015203:Reproducibility of Results