title: Synthesis and antioxidant activity of 4-[2-(3,5-dimethoxyphenyl)ethenyl]-1,2-benzenediol, a metabolite of Sphaerophysa salsula.
abstract: 4-[2-(3,5-Dimethoxyphenyl)ethenyl]-1,2-benzenediol (7), a stilbene isolated from Sphaerophysa salsula, was synthesized from 3,4-dihydroxybenzaldehyde (1) in five steps in an overall yield of 33%. The spectral data for synthetic 7 are in good agreement with those of the natural product. Hydroxystilbene 7 showed potent antioxidative activity.
authors.affiliation: Laila Impex R&D Center, Unit I, Phase III, Jawahar Autonagar, Vijaywada, India.
authors.forename: Somepalli
authors.initials: S
authors.lastname: Venkateswarlu
authors.forename: Boyina
authors.initials: B
authors.lastname: Satyanarayana
authors.forename: Chillara V
authors.initials: CV
authors.lastname: Sureshbabu
authors.forename: Gottumukkala V
authors.initials: GV
authors.lastname: Subbaraju
mesh_terms: D000975:Antioxidants / Q000032:analysis*; D001555:Benzene Derivatives / Q000032:analysis*; D002396:Catechols / Q000032:analysis* / Q000138:chemical synthesis; D007887:Fabaceae / Q000378:metabolism*; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D012997:Solvents; D013267:Stilbenes / Q000032:analysis* / Q000138:chemical synthesis
chemical_list: C488365:4-(2-(3,5-dimethoxyphenyl)ethenyl)-1,2-benzenediol; D000975:Antioxidants; D001555:Benzene Derivatives; D002396:Catechols; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D012997:Solvents; D013267:Stilbenes