Introduction of computational models to PhysioNet.
PhysioNet is a national research resource that provides experimental data sets and open-source software for their analysis. Computational modeling can complement studies of these experimental data sets so as to facilitate the advancement of physiologic research. Thus, in order to introduce computational models to PhysioNet, we have developed and posted a cardiovascular model designed for research that generates reasonable human pulsatile hemodynamic waveforms, cardiac output and venous return curves, and beat-to-beat variability. Some of the key features of the software include: 1) compatibility with PhysioNet's open-source data analysis software; 2) online viewing and parameter updating as the data are being calculated; 3) off-line viewing after completion of the simulation; 4) pre-compiled Linux binaries; 5) open-source code that may be compiled on other platforms; and 6) an extensive user's manual and software guide.
Mukkamala
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R
Harvard-MIT Division of Health Sciences and Technology, Cambridge, USA. rmukkama@mit.edu
Moody
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GB
Mark
R G
RG
D002302:Cardiac Output / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D003198:Computer Simulation; D016208:Databases, Factual; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D020407:Internet; D008955:Models, Cardiovascular; D012106:Research; D012984:Software