[The efficiency and direction of thymus changes after whole-body exposure of mice to the weak electromagnetic field are determined by the initial status of the thymus].
The work presents results of the experimental study on thymus changes developing after whole-body exposure of mice to ultralow power pulse-modulated electromagnetic field (carrying frequency 2.39 GHz, modulating pulses with frequency 4 Hz, duration of impulses 0.025 sec, average power density 60 mW/cm2, absorbed dose 0.086 J/g or 0.172 J/g). It was shown that a percent of the microwave induced increase or decrease of thymus mass and the number of cells in the organ (y) are determined by the initial mass or number of cells in thymus accordingly to equation of linear regression: (yx = 215-2.25x, where x is the thymus mass of control animals (in a range 31-63 mg) and (yx = 178.6-41x, where x is the initial number of cells in thymus (in a range 0.6 x 10(8)-2.6 x 10(8)) reduced by a factor of 10(8).
Semin
Iu A
IuA
Medical Radiological Research Center, Russian Academy of Medical Science, Obninsk, 249036 Russia. mrrc@obninsk.ru
Zhavoronkov
L P
LP
Voron'ko
Ia V
IaV
Shvartsburg
L K
LK
Rozhkova
O M
OM
D000818:Animals; D003627:Data Interpretation, Statistical; D004574:Electromagnetic Fields; D005260:Female; D016014:Linear Models; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000528:radiation effects; D051379:Mice; D008810:Mice, Inbred C57BL; D008872:Microwaves; D011829:Radiation Dosage; D013950:Thymus Gland / Q000166:cytology / Q000528:radiation effects*; D013997:Time Factors; D014916:Whole-Body Irradiation