[Vascular access, an underestimated source of inflammation in dialysis patients].
The surveillance of inflammation in dialysis patient, by means of sensitive markers such as CRP, is strongly recommended in a continuous quality improvement treatment approach. Chronic inflammation being deleterious via several pathways including malnutrition, accelerated arteriosclerosis and beta 2M-amyloidosis, microinflammation must diagnosed and corrected as soon as possible in dialysis patients. Vascular access represents an underestimated source of inflammation in hemodialysis patients. In the absence of organic cause of inflammation, the vascular access should be always incriminated and meticulously investigated. Withdrawing the suspected prosthetic or unused material (PTFE or catheter) should be considered as the best way of correcting the inflammation and restoring the recombinant erythropoietin (EPO) activity in the dialysis patient.
Canaud
B
B
Service de néphrologie, Institut de recherche et formation en dialyse, Hôpital Lapeyronie, Centre hospitalier universitaire de Montpellier. b-canaud@chu-montpellier.fr
Sénécal
L
L
Leray-Moragués
H
H
Picard-Gontiers
A
A
Terrier
N
N
Morena
M
M
Cristol
J P
JP
D000208:Acute Disease; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D002908:Chronic Disease; D006801:Humans; D007249:Inflammation / Q000209:etiology* / Q000517:prevention & control; D006435:Renal Dialysis / Q000379:methods*