title: Evaluation of the harmonized alert sensing technology device for hemodynamic monitoring in chronic hemodialysis patients.
abstract: The Harmonized Alert Sensing Technology (HASTE) device was developed to overcome the primary shortcomings of interval based noninvasive blood pressure (BP) monitoring. This study was conducted to assess the reliability of the HASTE system compared with standard cuff BP values in patients on hemodialysis. A total of 1,370 HASTE measurements were compared with oscillometric standard cuff systolic BP values in 42 sessions of 15 patients on hemodialysis. The average discrepancy between the HASTE and cuff systolic BP was 1.41 +/- 16.90 mm Hg. Compared with cuff measurements, 31% of systolic BP fell within a range of 5 mm Hg difference, 57% of systolic BP fell within 10 mm Hg, and 73% of systolic BP fell within a 15 mm Hg band. According to British Hypertension Society standards or Association for the Advancement of Medical Instrumentation criteria, the current HASTE method did not perform well. Technology to provide noninvasive hemodynamic monitoring is, however, in its developmental stage. The effort at continuous systolic pressure monitoring using existing, readily available, and frequently used techniques is exciting. Although the HASTE system as currently configured and calibrated did not adequately perform, variations in site analysis and conversion factors may increase pressure sensitivity and tracking over the course of a standard dialysis treatment.
authors.affiliation: Department of Nephrology/Hypertension, Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: Aykut
authors.initials: A
authors.lastname: Sifil
authors.forename: Dale
authors.initials: D
authors.lastname: Bednarz
authors.forename: Brett
authors.initials: B
authors.lastname: Larive
authors.forename: Michelle
authors.initials: M
authors.lastname: Garcia
authors.forename: Sey Mon
authors.initials: SM
authors.lastname: Lau
authors.forename: Emil P
authors.initials: EP
authors.lastname: Paganini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000295:instrumentation*; D001810:Blood Volume; D002138:Calibration; D004868:Equipment Failure; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D006435:Renal Dialysis / Q000379:methods* / Q000592:standards