[Expression of S100 in oral submucose fibrosis].
OBJECTIVE
To study the expression of S100 in oral submucose fibrosis(OSF).


METHODS
Immunohistochemistry assay was performed on 10 cases of OSF, 10 cases of oral epithelial dysplasia (OED) and 8 cases of normal oral epithelium using monoclonal antibody against S100 protein.


RESULTS
S100 did not express in the normal oral muscosal epithelium. The S100 positive nuclear staining was found in 50% of the OSF and OED cases, which was significantly higher than that in the normal oral epithelium (P < 0.05). But the positive staining in the OSF and OED cases had no difference (P > 0.05).


CONCLUSIONS
S100 expression is closely related to the development of OSF and OED. The positive staining expression in the OSF and OED cases is the same.
Xie
Xiao-li
XL
Department of Stomatology, Xiangya Hospital, Central South University, Changsha 410008, China.
Tang
Zhan-gui
ZG
Yao
Zhi-gang
ZG
D006801:Humans; D007150:Immunohistochemistry; D009061:Mouth Mucosa / Q000378:metabolism* / Q000473:pathology; D009914:Oral Submucous Fibrosis / Q000378:metabolism*; D011230:Precancerous Conditions / Q000378:metabolism; D009418:S100 Proteins / Q000032:analysis / Q000378:metabolism*
D009418:S100 Proteins