Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South Korea.
Macrolide resistance was detected in 64 of 77 (83.1%) Streptococcus pneumoniae isolates from South Korea. Seven (10.9%) isolates contained only mef(A), 32 (50%) contained only erm(B), and 25 (39.1%) contained mef(A) and erm(B). Nineteen isolates containing mef(A) and erm(B) belonged to serotype 19F, and seven isolates were identical to the Taiwan(19F)-14 clone.
Waites
Ken B
KB
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA. waites@path.uab.edu
Jones
Kellie E
KE
Kim
Kyung Hyo
KH
Moser
Stephen A
SA
Johnson
Crystal N
CN
Hollingshead
Susan K
SK
Kang
Eun-Suk
ES
Hong
Ki Sook
KS
Benjamin
William H
WH
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D006801:Humans; D007723:Korea; D018942:Macrolides / Q000494:pharmacology*; D008565:Membrane Proteins / Q000235:genetics*; D008780:Methyltransferases / Q000235:genetics*; D010802:Phylogeny; D011008:Pneumococcal Infections / Q000175:diagnosis*; D012703:Serotyping / Q000379:methods; D013296:Streptococcus pneumoniae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D018942:Macrolides; C117866:MefA protein, Streptococcus; D008565:Membrane Proteins; D008780:Methyltransferases; C035181:rRNA (adenosine-O-2'-)methyltransferase