Angioganglioglioma: a transitional form between angioglioma and gangioglioma?
The authors describe for the first time an unusual cerebral tumor with unique clinical history, composed of 3 components: pilocytic astrocytoma, vascular proliferations similar to those described as arteriovanous malformations, and a neoplastic ganglion component. These three components were intimately entangled and created the tumor mass. Thus the authors propose the term angioganglioglioma for this entity. The relation to the historically defined anglioglioma and tumors related to ganglioglioma and dysembryoplastic neuroepithelial tumor is discussed. The authors believe that this lesion, in regard to the clinical presentation (long course of the disease, clinical symptoms), is closely associated with ganglioglioma and, with other morphological features, also to angioglioma. Further, it may constitute a new distinct clinicopathological entity with neoplastic and hamartomatous features.
Kupnicka
Dorota Jesionek
DJ
Department of Tumour Pathology, Medical University of Lodz, Lodz, Poland.
Sikorska
Beata
B
Klimek
Andrzej
A
Kordek
Radzislaw
R
Liberski
Pawel P
PP
D001254:Astrocytoma / Q000473:pathology* / Q000503:physiopathology / Q000648:ultrastructure; D001932:Brain Neoplasms / Q000473:pathology* / Q000503:physiopathology* / Q000648:ultrastructure; D018303:Ganglioglioma / Q000473:pathology* / Q000503:physiopathology / Q000648:ultrastructure; D006222:Hamartoma / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure; D006391:Hemangioma / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D002538:Intracranial Arteriovenous Malformations / Q000473:pathology* / Q000503:physiopathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018302:Neoplasms, Neuroepithelial / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure