title: Color Doppler imaging in ocular hypertension and open-angle glaucoma.
abstract: OBJECTIVE
  To quantify the retrobulbar hemodynamics of patients with ocular hypertension and open-angle glaucoma and to compare it with that of normal subjects.
  
  
  METHODS
  Nineteen eyes of 19 ocular hypertensive patients, 19 eyes of 19 open-angle glaucoma patients and 19 eyes of 19 normal subjects were recruited from our clinic and underwent color Doppler imaging evaluation of the ophthalmic, posterior ciliary, and central retinal arteries. The peak systolic and end-diastolic blood flow velocities and resistivity indices of all retrobulbar vessels were measured.
  
  
  RESULTS
  The retrobulbar blood flow velocities were lower and resistivity indices were higher in all retrobulbar vessels in ocular hypertensive patients than in normal subjects. The differences, however, did not reach statistical significance ( P>0.05). Glaucoma patients had lower end-diastolic velocities and higher resistivity indices than did normal subjects in the ophthalmic ( P=0.003 and P=0.003, respectively), posterior ciliary ( P=0.001 and P<0.001, respectively), and central retinal arteries ( P=0.03 and P=0.04, respectively). Glaucoma patients had significantly lower end-diastolic velocity and higher resistivity index than did patients with ocular hypertension in the posterior ciliary artery ( P=0.04 and P=0.001, respectively).
  
  
  CONCLUSIONS
  This study suggests that ocular hypertensive patients have more normal blood flow than do glaucoma patients, because all retrobulbar homodynamic measurements in ocular hypertension range between glaucoma and normal subjects. On the other hand, glaucoma is associated with blood-flow velocity reduction and resistivity index elevation in all retrobulbar arteries.
authors.affiliation: Department of Ophthalmology, University of Kırıkkale, Kırıkkale, 71100, Turkey. cengizakarsu@hotmail.com.|Çağdaş Sokak 37/13, 06130, Aydınlıkevler, Ankara, Turkey. cengizakarsu@hotmail.com.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Akarsu
authors.affiliation: Department of Radiology, University of Kırıkkale, Kırıkkale, 71100, Turkey.
authors.forename: M Yasemin Karadeniz
authors.initials: MYK
authors.lastname: Bilgili
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000502:physiology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D012039:Regional Blood Flow; D012161:Retinal Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D018615:Ultrasonography, Doppler, Color