Fluorescein and indocyanine green angiography findings in Behçet's disease.
OBJECTIVE
To evaluate and compare the fluorescein (FA) and indocyanine green angiographic (ICGA) findings, and to investigate the choroidal involvement in Behçet's disease.


METHODS
FA and ICGA were performed on 112 eyes of 62 patients with Behçet's disease, between November 1993 and July 2002, using Topcon IMAGEnet Digital System. Patients were aged 16-50 years; 48 (77.4%) were male and 14 (22.6%) were female.


RESULTS
FA showed dye leakage from retinal vessels in 57 (50.9%) eyes, cystoid macular oedema in 18 eyes (16.1%), optic disc oedema in four eyes (3.6%), disc neovascularisation in three eyes (2.7%), and retinal neovascularisation in two eyes (1.8%). ICGA showed hyperfluorescent lesions in 40 eyes (35.7%), hypofluorescent lesions in 17 eyes (15.2%), hyperfluorescent and hypofluorescent lesions in 12 (10.7%) eyes, ICG leakage from choroidal vessels in 11 eyes (9.8%), irregular filling of choriocapillaris in five eyes (4.5%), and choroidal filling defect in four eyes (3.6%). Hyperfluorescent and hypofluorescent lesions which were seen in 53 out of 69 eyes (76.8%) on ICGA, were not visible on FA. 55 eyes (49.1%) showed hyperfluorescence on the disc on both FA and ICGA, whereas 36 (32.1%) showed hyperfluorescence only on FA.


CONCLUSIONS
The hyperfluorescence and/or hypofluorescence, irregular filling of the choriocapillaris, choroidal filling defect, and ICG leakage from choroidal vessels seen only on ICGA may suggest choroidal involvement in Behçet's disease.
Atmaca
L S
LS
Ankara University, School of Medicine, Department of Ophthalmology, Gazi Mustafa Kemal Bulvari 23/1, Kizilay 06440, Ankara, Turkey. leylaatmaca@ttnet.net.tr
Sonmez
P A
PA
D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis*; D002829:Choroid / Q000098:blood supply* / Q000000981:diagnostic imaging; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D011859:Radiography
D004396:Coloring Agents; D007208:Indocyanine Green