[Effect of vinpocetine on cerebral circulation in rats after exposure to radiation].
Vinpocetine (5 mg/kg) increases the cerebral blood flow rate, retains autoregulation, and positively influences carbohydrate and transcapillary metabolism in rats upon single irradiation to a dose of 2 Gy.
Vereshchagin
V K
VK
Department of Extremal Medicine, State Pharmaceutical Academy, pr. Kalinina 11, Pyatigorsk, 357533 Russia.
D000222:Adaptation, Physiological / Q000187:drug effects / Q000528:radiation effects; D000284:Administration, Oral; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects / Q000528:radiation effects; D001921:Brain / Q000098:blood supply / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D007274:Injections, Intraperitoneal; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000378:metabolism / Q000503:physiopathology* / Q000517:prevention & control; D051381:Rats; D014655:Vascular Resistance / Q000187:drug effects / Q000528:radiation effects; D014748:Vinca Alkaloids / Q000008:administration & dosage / Q000494:pharmacology*
D018696:Neuroprotective Agents; D014748:Vinca Alkaloids; C013983:vinpocetine