title: [Effects of ursolic acid on liver-protection and bile secretion].
abstract: OBJECTIVE
  To study the liver-protection and promoting bile secretion of ursolic acid.
  
  
  METHODS
  Ursolic acid was administrated to the mice with liver injury induced by CCl4 or APIT. ALT, AST levels in serum were examined. The bile flow rate and the concentration of the main components in the bile of rats administrated with ursolic acid were estimated.
  
  
  RESULTS
  Ursolic acid could decrease the serum ALT, AST, SB levels in the mice treated with CCl4 or APIT, promote the secretion of bile and increase the concentration of bilirubin in the bile.
  
  
  CONCLUSIONS
  Ursolic acid exhibited significant liver protection and promoting blie secretion.
authors.affiliation: Yichun College, Yichun, Jiangxi 336000.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Xiong
authors.forename: Weiyun
authors.initials: W
authors.lastname: Chen
authors.forename: Jianglong
authors.initials: J
authors.lastname: Cui
authors.forename: Shaobo
authors.initials: S
authors.lastname: Yi
authors.forename: Ziwen
authors.initials: Z
authors.lastname: Zhang
authors.forename: Kaiquan
authors.initials: K
authors.lastname: Li
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001646:Bile / Q000378:metabolism*; D002252:Carbon Tetrachloride Poisoning; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005260:Female; D017879:Isothiocyanates; D008099:Liver / Q000473:pathology; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D020011:Protective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D027923:Sambucus / Q000737:chemistry; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D000097245:Ursolic Acid
chemical_list: D000410:Alanine Transaminase; D001219:Aspartate Aminotransferases; D004365:Drugs, Chinese Herbal; D017879:Isothiocyanates; D020011:Protective Agents; D014315:Triterpenes; D000097245:Ursolic Acid; C058305:phenethyl isothiocyanate