The report of the cartilage regeneration using total joint regeneration system (internal-fixator type).
A new therapeutic system called the "total joint regeneration system" is proposed as a treatment for osteoarthritis and rheumatoid arthritis. We have developed devices which allow the regeneration of damaged cartilage under noninvasive mechanical stimulation. This paper introduces the basic concepts of total joint regeneration and reports the results of the first animal experiment using an internal-fixator device using rabbits and a dog.
Aoki
Hideyuki
H
Department of Orthopaedic Surgery, School of Medicine, Toho University, 6-11-1 Omorinishi, Ota-ku, Tokyo 143-8541, Japan.
Tomita
Nohide
N
Harada
Yasuji
Y
Hattori
Koji
K
Sonobe
Masato
M
Suguro
Toru
T
D000818:Animals; D001863:Bone Screws; D002357:Cartilage Diseases / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery*; D002358:Cartilage, Articular / Q000293:injuries / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D019544:Equipment Failure Analysis; D016268:Internal Fixators; D007718:Knee Injuries / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D008297:Male; D011474:Prosthesis Design; D011817:Rabbits; D012038:Regeneration; D016896:Treatment Outcome; D014945:Wound Healing