title: Morphofunctional visualization of MR-mammography in virtual reality.
abstract: In view of an increasing use of breast MRI supplementing X-ray mammography, the purpose of this study was the development of a method for fast and efficient analysis of dynamic MR image series of the female breast. The dynamic image data sets were analyzed by tracer kinetic modeling in order to describe the physiological processes underlying the contrast enhancement in mathematical terms and thus to enable the estimation of functional tissue specific parameters, reflecting the status of microcirculation. To display morphological and functional tissue information simultaneously, a multidimensional real-time visualization system (using 3D-texture mapping) was developed, which enables a practical and intuitive human-computer interface in virtual reality.
authors.affiliation: GSF-National Research Center for Environment and Health, Institute of Medical Informatics Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. englmeier@gsf.de
authors.forename: K H
authors.initials: KH
authors.lastname: Englmeier
authors.forename: G
authors.initials: G
authors.lastname: Hellwig
authors.forename: J
authors.initials: J
authors.lastname: Griebel
authors.forename: S
authors.initials: S
authors.lastname: Delorme
authors.forename: M
authors.initials: M
authors.lastname: Siebert
authors.forename: G
authors.initials: G
authors.lastname: Brix
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008327:Mammography / Q000295:instrumentation*; D015233:Models, Statistical; D010599:Pharmacokinetics; D011857:Radiographic Image Interpretation, Computer-Assisted; D014584:User-Computer Interface