title: [Population genetic analysis of the heritability of gutteral pouch tympany in Arabian purebred foals].
abstract: The objective of the present study was to analyse the importance of the influences of the sex, inbreeding coefficient and the additive genetic contribution to the occurrence of guttural pouch tympany in Arabian foals. Horses affected by guttural pouch tympany were ascertained in the Clinic for Horses, School of Veterinary Medicine Hannover. The data comprised 27 Arabian purebred foals with guttural pouch tympany. Of these 27 animals 22 were patients of the Clinic for Horses between 1994 and 2001 and 5 Arabian foals were sampled on the studs. Information on the pedigrees of these patients allowed us to sort in the affected foals into four families with a total of 276 animals. Female foals were more often affected by guttural pouch tympany. The difference was 11.9% in favour of female foals. The size of the inbreeding coefficient was not important for the occurrence of guttural pouch tympany. The heritability estimate for the frequency of guttural pouch tympany using a threshold model was 0.49 +/- 0.28. This is the first report that could show a genetic component responsible for guttural pouch tympany in foals.
authors.affiliation: Klinik für Pferde, Tierrztlichen Hochschule Hannover.
authors.forename: I
authors.initials: I
authors.lastname: Blazyczek
authors.forename: H
authors.initials: H
authors.lastname: Hamann
authors.forename: B
authors.initials: B
authors.lastname: Ohnesorge
authors.forename: E
authors.initials: E
authors.lastname: Deegen
authors.forename: O
authors.initials: O
authors.lastname: Distl
mesh_terms: D000818:Animals; D005064:Eustachian Tube / Q000473:pathology; D005260:Female; D006734:Horse Diseases / Q000453:epidemiology / Q000235:genetics*; D006736:Horses; D007178:Inbreeding; D008297:Male; D008957:Models, Genetic; D010608:Pharyngeal Diseases / Q000453:epidemiology / Q000235:genetics / Q000662:veterinary*; D010614:Pharynx / Q000473:pathology; D012737:Sex Factors