Kaposi's sarcoma in a patient with severe relapsing polychondritis.
This report describes the case of a young man who developed Kaposi's sarcoma (KS) after corticosteroid treatment for severe tracheal involvement of relapsing polychondritis (RP). The etiopathogenetic mechanisms that may have led to the evolution of this unusual neoplasm are discussed. To our knowledge, this is the first case reported of concomitant RP and KS.
Manghani
Mona K
MK
120 Austrasse, 4051, Basel, Switzerland. mmanghani@hotmail.com
Andrews
Jacqueline
J
Higgens
Clare S
CS
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000009:adverse effects; D019288:Herpesvirus 8, Human / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007830:Larynx / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D008297:Male; D011081:Polychondritis, Relapsing / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000139:chemically induced* / Q000473:pathology / Q000821:virology*; D014132:Trachea / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide