Sulfur-containing compounds from Clinacanthus siamensis.
Two new sulfur-containing compounds, trans-3-methylsulfonyl-2-propenol (1) and trans-3-methylsulfinyl-2-propenol (2) were isolated together with trans-3-methylthioacrylamide (3), entadamide A (4) and entadamide C (5) from the leaves of Clinacanthus siamensis. The structures were established on the basis of the spectroscopic data. The compounds were tested for antimalarial and antimycobacterial activity.
Tuntiwachwuttikul
Pittaya
P
Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom, Thailand. Pittayat@su.ac.th
Pootaeng-on
Yupa
Y
Pansa
Pootchana
P
Srisanpang
Thongchai
T
Taylor
Walter Charles
WC
D027901:Acanthaceae; D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000254:growth & development; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves; D010963:Plasmodium falciparum / Q000187:drug effects / Q000254:growth & development; D013457:Sulfur Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
D000995:Antitubercular Agents; D010936:Plant Extracts; D013457:Sulfur Compounds