title: [Age-specific reference ranges for serum prostate-specific antigen in Chinese men].
abstract: OBJECTIVE
  To evaluate the age-specific reference ranges for serum prostate-specific antigen in Chinese men.
  
  
  METHODS
  Serum tPSA and fPSA were measured by enzyme-linked immunosorbent assay (ELISA) and fPSA/tPSA ratio was calculated in 1,096 health Chinese men of 23 - 85 years old. The relationship between age and PSA indexes was analyzed with simple linear regression.
  
  
  RESULTS
  The recommended age-specific reference range (95th percentile) for serum PSA for Chinese were: 1.20 microg/L for 20-29 years; 1.21microg/L for 30-39 years; 1.23 microg/L for 40-49 years; 2.35 microg/L for 50-59 years; 3.20 microg/L for 60-69 years; 3.39 microg/L for >or= 70 years. The serum PSA concentration correlated directly with age. The age-specific reference range was lower for Chinese men than not only for white and black men, but also for Japanese and Koreans men.
  
  
  CONCLUSIONS
  The age-specific reference ranges for serum PSA are lower significantly for Chinese men than for black, white men, even for Japanese and Koreans men. Study the normal upper limit of PSA and the age-specific reference ranges for serum prostate-specific antigen in Chinese men is very important.
authors.affiliation: Institute of Urology of Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Ming-zhu
authors.initials: MZ
authors.lastname: Wang
authors.forename: Zhong-wei
authors.initials: ZW
authors.lastname: Gao
authors.forename: Da-lin
authors.initials: DL
authors.lastname: He
authors.forename: Xing-fa
authors.initials: XF
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: He
authors.forename: Wu-sheng
authors.initials: WS
authors.lastname: Wang
authors.forename: Xun-yi
authors.initials: XY
authors.lastname: Nan
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D044383:Black People; D002681:China / Q000208:ethnology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D012016:Reference Values; D044465:White People
chemical_list: D017430:Prostate-Specific Antigen