title: Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South Korea.
abstract: Macrolide resistance was detected in 64 of 77 (83.1%) Streptococcus pneumoniae isolates from South Korea. Seven (10.9%) isolates contained only mef(A), 32 (50%) contained only erm(B), and 25 (39.1%) contained mef(A) and erm(B). Nineteen isolates containing mef(A) and erm(B) belonged to serotype 19F, and seven isolates were identical to the Taiwan(19F)-14 clone.
authors.affiliation: Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA. waites@path.uab.edu
authors.forename: Ken B
authors.initials: KB
authors.lastname: Waites
authors.forename: Kellie E
authors.initials: KE
authors.lastname: Jones
authors.forename: Kyung Hyo
authors.initials: KH
authors.lastname: Kim
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Moser
authors.forename: Crystal N
authors.initials: CN
authors.lastname: Johnson
authors.forename: Susan K
authors.initials: SK
authors.lastname: Hollingshead
authors.forename: Eun-Suk
authors.initials: ES
authors.lastname: Kang
authors.forename: Ki Sook
authors.initials: KS
authors.lastname: Hong
authors.forename: William H
authors.initials: WH
authors.lastname: Benjamin
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D006801:Humans; D007723:Korea; D018942:Macrolides / Q000494:pharmacology*; D008565:Membrane Proteins / Q000235:genetics*; D008780:Methyltransferases / Q000235:genetics*; D010802:Phylogeny; D011008:Pneumococcal Infections / Q000175:diagnosis*; D012703:Serotyping / Q000379:methods; D013296:Streptococcus pneumoniae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D018942:Macrolides; C117866:MefA protein, Streptococcus; D008565:Membrane Proteins; D008780:Methyltransferases; C035181:rRNA (adenosine-O-2'-)methyltransferase