title: Fulminant meningococcemia and acute renal failure in a 3-year-old boy.
abstract: Acute renal failure is a common occurrence in sepsis, but is rarely reported in meningococcemia. We present a young child diagnosed with fulminant meningococcemia who had several poor prognostic factors, including hypotension, thrombocytopenia, purpura fulminans, seizures, the absence of meningitis with meningococcemia, and acute renal failure, which was successfully treated with peritoneal dialysis. Peritoneal dialysis was started on the 5th day because the patient had been anuric for 48 h. At that time, analysis showed that the child was both hypokalemic and hypophosphatemic. His serum blood urea nitrogen was 61 mg/dl, creatinine 2.75 mg/dl, potassium 2.8 mEq/l, and phosphorus 0.7 mg/dl. Urine output began on the 12th day post admission and normalization of serum creatinine was achieved on the 26th day. In conclusion, renal failure is an important complication of meningococcemia and, to be effective, sometimes long-term peritoneal dialysis is required. Profound metabolic abnormalities, such as hypokalemia and hypophosphatemia, may occur paradoxically in the presence of oliguria.
authors.affiliation: Department of Pediatrics, Celal Bayar University, Manisa, Turkey. ipek.akil@bayar.edu.tr
authors.forename: Ipek
authors.initials: I
authors.lastname: Akil
authors.forename: Hasan
authors.initials: H
authors.lastname: Yüksel
authors.forename: Senol
authors.initials: S
authors.lastname: Coskun
authors.forename: Dilek
authors.initials: D
authors.lastname: Yilmaz
authors.forename: Ali
authors.initials: A
authors.lastname: Onag
mesh_terms: D016470:Bacteremia; D002675:Child, Preschool; D006801:Humans; D007008:Hypokalemia / Q000150:complications; D017674:Hypophosphatemia / Q000150:complications; D008297:Male; D008589:Meningococcal Infections / Q000150:complications / Q000382:microbiology*; D010530:Peritoneal Dialysis; D051437:Renal Insufficiency / Q000382:microbiology* / Q000628:therapy