[A case of lymph node metastasis after total laryngectomy successfully treated with chemoradiotherapy with TS-1].
A patient with advanced recurrent laryngeal cancer complicated with cervical lymph node metastasis was successfully treated with chemoradiotherapy with an oral anticancer drug, TS-1. TS-1 was administered at a dose of 120 mg/day. One course consisted of consecutive administration of TS-1 for 28 days and withdrawal for 14 days. During chemotherapy, the patient received concomitant radiotherapy (60 Gy). At the end of 2 courses, a partial response of the neck metastasis was achieved.
Suzuki
Saori
S
Dept. of Otolaryngology, Tokyo Women's Medical University School of Medicine.
Yoshihara
Toshio
T
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D004338:Drug Combinations; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D007825:Laryngectomy; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage*; D011725:Pyridines / Q000008:administration & dosage*; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy* / Q000556:secondary; D005641:Tegafur / Q000008:administration & dosage*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid