Severe neutrophilia in an infant with persistent pulmonary hypertension of the newborn.
We report the case of a term male infant with severe persistent pulmonary hypertension of the newborn, who developed massive neutrophilia of unknown etiology. An extensive evaluation failed to disclose an obvious cause for his neutrophilia. A bone marrow aspirate was performed and was consistent with a leukemoid reaction. This paper reviews the neonatal leukemoid reaction and its significance.
Engmann
Cyril
C
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
Donn
Steven M
SM
D006801:Humans; D007231:Infant, Newborn; D007955:Leukemoid Reaction / Q000209:etiology*; D007958:Leukocyte Count; D008297:Male; D009504:Neutrophils; D010547:Persistent Fetal Circulation Syndrome / Q000150:complications*