title: [A case of multiple myeloma presenting as giant chest wall tumors with calcification].
abstract: A 60-year-old man was admitted for investigation of an abnormality detected in chest radiography: a giant tumor with calcification in the right middle lung field. A computed tomography (CT) scan revealed multiple tumors with calcification on the posterior chest wall. Histological analysis of the tumor specimen obtained by surgical biopsy demonstrated an increasing number of plasma cells accompanied with the deposition of amyloid. A bone marrow biopsy contained over 50% of plasma cells. We therefore diagnosed these tumors as multiple myeloma. It has been reported that multiple myeloma is usually characterized by osteolytic lesions; osteosclerotic changes are rare. Multiple myeloma should be taken into account as one of the causes of a chest wall tumor even if it is diffusely calcified.
authors.affiliation: Department of Respiratory Medicine, Seirei Hamamatsu General Hospital.
authors.forename: Kengo
authors.initials: K
authors.lastname: Murata
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Horie
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kominami
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tomita
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Oode
authors.forename: Futoshi
authors.initials: F
authors.lastname: Toyoda
authors.forename: Yoshirou
authors.initials: Y
authors.lastname: Ootsuki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Shimizu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D001854:Bone Marrow Cells / Q000473:pathology; D002114:Calcinosis; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis / Q000473:pathology*; D010026:Osteosclerosis; D010950:Plasma Cells / Q000473:pathology; D013899:Thoracic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D035441:Thoracic Wall