title: Mid-systolic septal deceleration. A new sign of left ventricular outflow tract obstruction obtained by color-coded tissue Doppler echocardiography.
abstract: Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by the presence of a dynamic left ventricular outflow tract gradient. We studied septal longitudinal motion by color coded tissue Doppler echocardiography in a 69-year old HOCM patient during and after catheter based treatment by trans coronary alcohol ablation of septal hypertrophy. The presence of dynamic left ventricular outflow tract obstruction was associated with a characteristic abrupt mid-systolic septal deceleration pattern in the tissue Doppler velocity trace. Five weeks after treatment, this pattern was no longer visible at rest.
authors.affiliation: Medizinische Klinik I, Universität-Klinikum Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany. olebreithardt@gmx.de
authors.forename: O A
authors.initials: OA
authors.lastname: Breithardt
authors.forename: B
authors.initials: B
authors.lastname: Stolle
authors.forename: A
authors.initials: A
authors.lastname: Franke
authors.forename: U
authors.initials: U
authors.lastname: Janssens
authors.forename: P
authors.initials: P
authors.lastname: Hanrath
authors.forename: H
authors.initials: H
authors.lastname: Kuhn
mesh_terms: D000368:Aged; D006328:Cardiac Catheterization; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D018618:Echocardiography, Doppler, Color; D004562:Electrocardiography; D000431:Ethanol / Q000008:administration & dosage; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology*; D006346:Heart Septum / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013599:Systole / Q000502:physiology*; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000431:Ethanol