title: Comparison of immediate results and follow-up of patients with single-vessel and multivessel coronary artery disease younger than 50 years of age undergoing coronary stent implantation.
abstract: OBJECTIVE
  To assess the in-hospital results and clinical follow-up of young patients (< 50 years) with multivessel coronary artery disease undergoing stent implantation in native coronary arteries and to compare their results with those of patients with single-vessel coronary artery disease.
  
  
  METHODS
  We retrospectively studied 462 patients undergoing coronary stent implantation. Patients were divided into 2 groups: group I (G-I) - 388 (84%) patients with single-vessel coronary artery disease; and group II (G-II) - 74 (16%) patients with multivessel coronary artery disease.
  
  
  RESULTS
  The mean age of the patients was 45 4.9 years, and the clinical findings at presentation and demographic data were similar in both groups. The rate of clinical success was 95% in G-I and 95.8% in G-II (P=0.96), with no difference in regard to in-hospital evolution between the groups. Death, acute myocardial infarction, and the need for myocardial revascularization during clinical follow-up occurred in 10.1% and 11.2% (P=0.92) in G-I and G-II, respectively. By the end of 24 months, the actuarial analysis showed an event-free survival of 84.6 % in G-I and 81.1% in G-II (P=0.57).
  
  
  CONCLUSIONS
  Percutaneous treatment with coronary stent implantation in young patients with multivessel disease may be safe with a high rate of clinical success, a low incidence of in-hospital complications, and a favorable evolution in clinical follow-up.
authors.affiliation: Hospital Beneficência Portuguesa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Alexandre L
authors.initials: AL
authors.lastname: Anello
authors.forename: Isaac
authors.initials: I
authors.lastname: Moscoso
authors.forename: Ricardo J
authors.initials: RJ
authors.lastname: Tófano
authors.forename: Adnan A
authors.initials: AA
authors.lastname: Salman
authors.forename: Salvador A B
authors.initials: SA
authors.lastname: Cristóvão
authors.forename: Maria Fernanda Z
authors.initials: MF
authors.lastname: Mauro
authors.forename: João
authors.initials: J
authors.lastname: Batista de O Neto
authors.forename: José A
authors.initials: JA
authors.lastname: Mangione
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications / Q000473:pathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome