title: A field study on the effect of the dietary use of a clinoptilolite-rich tuff, alone or in combination with certain antimicrobials, on the health status and performance of weaned, growing and finishing pigs.
abstract: This study was conducted to assess the effect of dietary use of a clinoptilolite-rich tuff (Cp) on health status and performance of weaned, growing and finishing pigs and its compatibility during simultaneous oral administration of antimicrobials (AM) such as enrofloxacin (E) or salinomycin (S). Weaners (720) were assigned in 2 experimental groups and 4 subgroups based on the inclusion or not of Cp and AM in their feed (subgroups: NC, ES, Cp, Cp+ES) in order to evaluate their health status, under PWDS prevailing herd conditions. A second part of the trial aimed to the evaluation of piglet performance under conditions with minimized PWDS herd risks. For this purpose, a second set of 264 weaners were assigned in 2 groups and 4 subgroups, in a respective manner. All piglets remained on-trial until slaughtering age; Cp was incorporated in their feed at a rate of 2% from the day of weaning until slaughtering. The health status evaluation consisted in monitoring piglets for adverse effects related to Cp consumption, average daily diarrhoea scoring during weaning and mortality rate calculations throughout. Performance evaluation included individual weighing at the end of weaning, growing and fattening periods and feed consumption assessments. Average daily gain (ADG), average daily feed intake (ADFI) and feed conversion ration (FCR) on a pen basis were further calculated. Cp ingestion was well tolerated by the piglets. Simultaneous administration of Cp and AM in feed, resulted in less severe forms of PWDS, which had a shorter clinical course (P<0.05). Mortality decreased (P<0.05) during the weaning period due to AM administration. Concerning mean pig body weight at the end of each production phase, both Cp and AM had favorable effects (P<0.05). ADG estimated for the whole observation period was improved (P<0.05) by Cp-use along with AM. FCR improvements (P<0.05) were noticed during the different stages of growth due to AM or Cp administration, while Cp/AM interaction was noticed only at weaning (P<0.05).
authors.affiliation: Clinic of Productive Animal Medicine, School of Veterinary Medicine, Aristotle University of Thessaloniki, 540 06 Thessaloniki, Macedonia, Greece.
authors.forename: D S
authors.initials: DS
authors.lastname: Papaioannou
authors.forename: C S
authors.initials: CS
authors.lastname: Kyriakis
authors.forename: C
authors.initials: C
authors.lastname: Alexopoulos
authors.forename: E D
authors.initials: ED
authors.lastname: Tzika
authors.forename: Z S
authors.initials: ZS
authors.lastname: Polizopoulou
authors.forename: S C
authors.initials: SC
authors.lastname: Kyriakis
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage; D003967:Diarrhea / Q000453:epidemiology / Q000662:veterinary; D004032:Diet / Q000662:veterinary*; D002149:Energy Intake; D000077422:Enrofloxacin; D024841:Fluoroquinolones / Q000008:administration & dosage; D011714:Pyrans / Q000008:administration & dosage; D015363:Quinolones / Q000008:administration & dosage; D013552:Swine / Q000254:growth & development*; D013553:Swine Diseases / Q000453:epidemiology; D014886:Weaning; D015430:Weight Gain / Q000187:drug effects; D017641:Zeolites; D000095662:Polyether Polyketides
chemical_list: D000890:Anti-Infective Agents; D000077422:Enrofloxacin; D024841:Fluoroquinolones; D011714:Pyrans; D015363:Quinolones; D017641:Zeolites; C083175:clinoptilolite; C010327:salinomycin; D000095662:Polyether Polyketides