title: Pax-7 immunoreactivity in the post-natal chicken central nervous system.
abstract: In this immunocytochemical study on the constitutive expression of Pax-7 protein in the postnatal chicken brain, Pax-7 showed region and cell type specific expression. In the optic tectum, only cells in grey matter showed positive immunoreactivities (IRs), whereas those in the white matters did not show any IRs. In thalamic nuclei and several pontine nuclei, we also localized Pax-7 positive IRs. On the contrary, in the cerebellum, Pax-7 was mainly localized within the Bergmann glia, whereas Purkinje cells did not show any IRs. In double immunolabelling studies, most of the Pax-7 IRs did not originate from neuroglial cells such as oligodendrocytes, microglia or astrocytes, but from neurons, with the exception of Bergmann glia in the cerebellum. The presence of Pax-7 IRs in the adult chicken brain could suggest that Pax-7 might play a role in maintaining normal physiological function in some postnatal chicken brain cells.
authors.affiliation: Department of Anatomy, Seoul National University College of Medicine, Seoul, Korea. drdoogi@chollian.net
authors.forename: D H
authors.initials: DH
authors.lastname: Shin
authors.forename: K-S
authors.initials: KS
authors.lastname: Lee
authors.forename: E
authors.initials: E
authors.lastname: Lee
authors.forename: Y P
authors.initials: YP
authors.lastname: Chang
authors.forename: J-W
authors.initials: JW
authors.lastname: Kim
authors.forename: Y S
authors.initials: YS
authors.lastname: Choi
authors.forename: B-S
authors.initials: BS
authors.lastname: Kwon
authors.forename: H W
authors.initials: HW
authors.lastname: Lee
authors.forename: S S
authors.initials: SS
authors.lastname: Cho
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology* / Q000378:metabolism; D002531:Cerebellum / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D002645:Chickens / Q000033:anatomy & histology / Q000235:genetics / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000032:analysis* / Q000096:biosynthesis / Q000235:genetics; D007150:Immunohistochemistry / Q000662:veterinary*; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics; D009457:Neuroglia / Q000378:metabolism; D009836:Oligodendroglia / Q000378:metabolism; D051763:PAX7 Transcription Factor; D011689:Purkinje Cells / Q000737:chemistry
chemical_list: D018398:Homeodomain Proteins; D009419:Nerve Tissue Proteins; D051763:PAX7 Transcription Factor