title: Immunotherapy and gene therapy of cancer using antibodies or their genes against tumor-associated antigens.
abstract: The purpose of this article is to review the current significance of anti-tumor-associated antigen (TAA) antibodies in the therapy of cancer. Current data suggest that antibodies or their genes against TAAs can be used in order to increase the tumor specificity of various therapeutic approaches against cancer, thereby enhancing the tumoricidal effect of each treatment while reducing the side-effects.
authors.affiliation: Department of Biochemistry, Fukuoka University School of Medicine, Fukuoka University Molecular Oncology Center, Fukuoka, Japan. kurokima@fukuoka-u.ac.jp
authors.forename: Masahide
authors.initials: M
authors.lastname: Kuroki
authors.forename: Hirotomo
authors.initials: H
authors.lastname: Shibaguchi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Imakiire
authors.forename: Koichi
authors.initials: K
authors.lastname: Uno
authors.forename: Kyoko
authors.initials: K
authors.lastname: Shirota
authors.forename: Takao
authors.initials: T
authors.lastname: Higuchi
authors.forename: Tomomi
authors.initials: T
authors.lastname: Shitama
authors.forename: Hiromi
authors.initials: H
authors.lastname: Yamada
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Hirose
authors.forename: Akihisa
authors.initials: A
authors.lastname: Nagata
authors.forename: Motomu
authors.initials: M
authors.lastname: Kuroki
mesh_terms: D000818:Animals; D000912:Antibodies, Neoplasm / Q000235:genetics* / Q000276:immunology / Q000627:therapeutic use*; D000951:Antigens, Neoplasm / Q000276:immunology*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D007116:Immunization, Passive / Q000379:methods*; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*
chemical_list: D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm