title: Cardiovascular changes during drainage of pericardial effusion by thoracoscopy.
abstract: BACKGROUND
  Cardiovascular changes during drainage of pericardial effusion are not well understood, and most studies are of systemic effects and not of right ventricular performance. Thoracoscopy is not widely used to drain pericardial effusions because of haemodynamic changes in relation to the use of single lung ventilation.
  
  
  METHODS
  We studied 16 patients undergoing partial pericardiectomy for pericardial effusion, using videothoracoscopy with a low-pressure pneumothorax (6 mm Hg). Cardiac output was measured by thermodilution with the patient anaesthetized in the supine position before the procedure; in the right lateral position after a low-pressure pneumothorax had been established; and after drainage of the pericardial effusion.
  
  
  RESULTS
  Before the procedure, cardiac output was low and central venous pressure and pulmonary artery occlusion pressure were increased. Systemic vascular resistance and arterial blood pressure were within normal limits. Cardiac filling pressure and pulmonary arterial pressure increased during the pneumothorax. After the drainage cardiac index increased and systemic and pulmonary vascular resistances were reduced.
  
  
  CONCLUSIONS
  Pericardial effusion reduces right ventricular distensibility, right and left systolic ventricular function, and cardiac output. Anaesthesia with mechanical ventilation and a low-pressure pneumothorax do not affect the circulation greatly. Drainage of the pericardial effusion allows cardiac distensibility to increase and cardiac performance changes to allow increased ejection.
authors.affiliation: Servicio de Cirugía I and Servicio de Anestesiología y Reanimación, Hospital Universitario Virgen de la Arrixaca, El Palmar S/N, Murcia E-30120, Spain. jumanjico@yahoo.com
authors.forename: J A
authors.initials: JA
authors.lastname: Fernández
authors.forename: R
authors.initials: R
authors.lastname: Robles
authors.forename: F
authors.initials: F
authors.lastname: Acosta
authors.forename: T
authors.initials: T
authors.lastname: Sansano
authors.forename: P
authors.initials: P
authors.lastname: Parrilla
mesh_terms: D000293:Adolescent; D000328:Adult; D002302:Cardiac Output; D004322:Drainage / Q000379:methods; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000503:physiopathology / Q000601:surgery*; D010492:Pericardiectomy / Q000379:methods*; D011031:Pneumothorax, Artificial / Q000379:methods; D020775:Thoracic Surgery, Video-Assisted; D014655:Vascular Resistance