Epoxidation of chiral camphor N-enoylpyrazolidinones with methyl(trifluoromethyl)dioxirane and urea hydrogen peroxide/acid anhydride: reversal of stereoselectivity.
Both diastereomeric isomers of epoxides with high optical purity are obtained when camphor N-methacryloylpyrazolidinone (1a) and N-tigloylpyrazolidinone (1b) are treated with a urea hydrogen peroxide/TFAA and methyl(trifluoromethyl)dioxirane, respectively.
Fan
Chai Ling
CL
Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan 116, ROC kchen@scc.ntnu.edu.tw
Lee
Wei-Der
WD
Teng
Nai-Wei
NW
Sun
Ying-Chieh
YC
Chen
Kwunmin
K