title: Multiple progressive intracerebral hemorrhages due to an angiosarcoma: a case report.
abstract: Identification of intracerebral hemorrhage (ICH) and the underlying cause is a common clinical problem. Rare causes of ICH can be particularly difficult to diagnose. We describe a man on oral anticoagulation with multiple progressive ICHs, who initially showed no signs of a malignant disease. After normalisation of all coagulation tests, the ICHs continued to spread. Autopsy examination revealed an angiosarcoma. Multiple progressive ICHs caused by an angiosarcoma that mainly affects the brain have not yet been described. In the presence of normal coagulation tests, further progression of ICH should raise questions about common causes of ICH such as oral anticoagulation in our case.
authors.affiliation: Department of Neurology, Technical University of Munich, Munich, Germany. mtwoke7@t-online.de
authors.forename: M
authors.initials: M
authors.lastname: Mühlau
authors.forename: J
authors.initials: J
authors.lastname: Schlegel
authors.forename: H G
authors.initials: HG
authors.lastname: Von Einsiedel
authors.forename: B
authors.initials: B
authors.lastname: Conrad
authors.forename: D
authors.initials: D
authors.lastname: Sander
mesh_terms: D000368:Aged; D001344:Autopsy; D001780:Blood Coagulation Tests; D001932:Brain Neoplasms / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000097:blood / Q000209:etiology*; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male