Dynamic interfaces between cells and surfaces: electroactive substrates that sequentially release and attach cells.
An electroactive substrate that combines dual dynamic properties is demonstrated. A monolayer is patterned to first release an immobilized ligand, and therefore adherent cells, on application of an electrical potential. Subsequently, electrical oxidation of the substrate results in immobilization of ligands, and migration of adherent cells.
Yeo
Woon-Seok
WS
The University of Chicago, Department of Chemistry, Institute for Biophysical Dynamics, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
Yousaf
Muhammad N
MN
Mrksich
Milan
M
D000818:Animals; D002448:Cell Adhesion; D004563:Electrochemistry; D005353:Fibronectins / Q000737:chemistry / Q000378:metabolism; D006873:Hydroquinones / Q000737:chemistry / Q000378:metabolism*; D051379:Mice; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism*; D011971:Receptors, Immunologic / Q000737:chemistry / Q000378:metabolism*; D018000:Receptors, Peptide / Q000737:chemistry / Q000378:metabolism*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D041701:Swiss 3T3 Cells
D005353:Fibronectins; D006873:Hydroquinones; D009842:Oligopeptides; D011971:Receptors, Immunologic; D018000:Receptors, Peptide; C051382:arginyl-glycyl-aspartic acid directed cell adhesion receptor; C047981:arginyl-glycyl-aspartic acid