title: QSAR study on 5-lipoxygenase inhibitors using distance-based topological indices.
abstract: QSAR study on a large set of 5-lipoxygenase inhibitors has been carried out using distance-based topological indices. Regression analysis of the data has indicated that an excellent model is obtained when these topological indices are combined with some classical molecular descriptors. The obtained models are critically discussed and examined.
authors.affiliation: QSAR and Computer Chemical Laboratories, APS University, Rewa-486 003, India.
authors.forename: Vijay K
authors.initials: VK
authors.lastname: Agrawal
authors.forename: Shahnaz
authors.initials: S
authors.lastname: Bano
authors.forename: Padmakar V
authors.initials: PV
authors.lastname: Khadikar
mesh_terms: D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D008956:Models, Chemical; D015394:Molecular Structure; D021281:Quantitative Structure-Activity Relationship; D012044:Regression Analysis
chemical_list: D016859:Lipoxygenase Inhibitors