title: [Heart failure, skin manifestations, enlarged hilar lymph nodes. Is it sarcoidosis?].
abstract: Sarcoidosis is defined as a multisystem disease of unknown genesis that affects in particular the middle-aged. In 80% of the cases, the acute form is associated with pulmonary manifestations, and in the majority of patients clears up--even in the absence of treatment--with no sequelae. The chronic version is characterized by the development of multiple pulmonary granulomas and progressive fibrosis. Subsequently, emphysema, cor pulmonale and right heart insufficiency develops. Almost 50% of chronic sarcoidosis patients have cardiac involvement with arrhythmias, heart block and the clinical picture of a cardiomyopathy, which in many cases leads to death--acutely (sudden cardiac death) or over the longer term. In manifest disease, treatment with steroids should be initiated and continued over a year. Conduction disorders require the implantation of a pacemaker.
authors.affiliation: malvine@t-online.de
authors.forename: E
authors.initials: E
authors.lastname: Bub
mesh_terms: D009202:Cardiomyopathies / Q000175:diagnosis* / Q000401:mortality; D002423:Cause of Death; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000209:etiology; D003937:Diagnosis, Differential; D005858:Germany; D006333:Heart Failure / Q000209:etiology* / Q000401:mortality; D006801:Humans; D006965:Hyperplasia; D008198:Lymph Nodes / Q000473:pathology*; D011379:Prognosis; D012507:Sarcoidosis / Q000175:diagnosis* / Q000401:mortality; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis* / Q000401:mortality; D012871:Skin Diseases / Q000175:diagnosis* / Q000401:mortality