Solvent effects on amphotericin B monolayers.
Monolayers of the antifungal antibiotic amphotericin B undergo the liquid expanded/liquid condensed state transition if spread from chloroform/methanol solvent. The transition disappeared after a long spreading time. The presence of the transition may be due to the retention of solvent and/or the presence of metastable aggregates of amphotericin B.
Sykora
Jennifer Cannon
JC
Department of Chemistry, Auburn University, Auburn, AL 36849, USA.
Neely
William C
WC
Vodyanoy
Vitaly
V
D000666:Amphotericin B / Q000737:chemistry*; D000935:Antifungal Agents / Q000737:chemistry; D002725:Chloroform / Q000737:chemistry*; D000432:Methanol / Q000737:chemistry*; D011312:Pressure; D012997:Solvents; D013499:Surface Properties
D000935:Antifungal Agents; D012997:Solvents; D002725:Chloroform; D000666:Amphotericin B; D000432:Methanol