title: Relationship between cycloplegic and wavefront-derived refraction.
abstract: OBJECTIVE
  To compare cycloplegic refractions to preoperative wavefront-derived refractions from three Hartmann-Shack-based wavefront devices.
  
  
  METHODS
  Ninety-nine eyes of 55 subjects were evaluated preoperatively using the LADARWave, WaveScan, and Zywave aberrometers. With cycloplegic refraction as the standard, the spherical equivalent refraction, sphere, and cylinder were compared to the wavefront-derived refractions using the three wavefront devices.
  
  
  RESULTS
  The LADARWave unit showed the highest correlation between wavefront-derived sphere and mean spherical equivalent refraction values relative to cycloplegic refraction, followed by Zywave and WaveScan. The WaveScan unit exhibited higher variability than the LADARWave or Zywave. Although Alcon Laboratories (LADARWave) and Bausch & Lomb Surgical (Zywave) recommend dilation, VISX specifically recommends against dilation in their WaveScan unit. All devices showed high cylinder error vectors when the cycloplegic cylinder was greater than 1.00 D.
  
  
  CONCLUSIONS
  Although wavefront-derived refractions appeared to correlate well to cycloplegic refractions, further research is required to reduce variability and improve the calculation of cylinder terms.
authors.affiliation: Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC 29425, USA.
authors.forename: Luis E
authors.initials: LE
authors.lastname: Fernández de Castro
authors.forename: Helga P
authors.initials: HP
authors.lastname: Sandoval
authors.forename: Oday
authors.initials: O
authors.lastname: Al Sarraf
authors.forename: David T
authors.initials: DT
authors.lastname: Vroman
authors.forename: Kerry D
authors.initials: KD
authors.lastname: Solomon
mesh_terms: D000328:Adult; D002924:Ciliary Body / Q000187:drug effects; D003519:Cyclopentolate / Q000008:administration & dosage*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008297:Male; D009184:Mydriatics / Q000008:administration & dosage*; D011680:Pupil / Q000502:physiology*; D012029:Refraction, Ocular / Q000187:drug effects / Q000502:physiology*
chemical_list: D009184:Mydriatics; D003519:Cyclopentolate