title: Carotid angioplasty and stenting with and without cerebral protection: clinical alert from the Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis (EVA-3S) trial.
abstract: OBJECTIVE
  Whether cerebral protection during carotid angioplasty and stenting (CAS) is associated with a lower risk of periprocedural stroke or death remains to be established. We report on 80 patients randomized in the CAS arm of the Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis trial comparing CAS (with or without cerebral protection) with carotid surgery in patients with recently symptomatic, severe carotid stenosis.
  
  
  METHODS
  The Safety Committee recommended stopping unprotected CAS, because the 30-day rate of stroke was 3.9 (0.9 to 16.7) times higher than that of CAS with cerebral protection (4/15 versus 5/58).
  
  
  CONCLUSIONS
  Although this result was not based on a randomized comparison of unprotected versus protected CAS, it suggests that the use of cerebral protection devices during CAS reduces periprocedural strokes.
authors.forename: J L
authors.initials: JL
authors.lastname: Mas
authors.forename: G
authors.initials: G
authors.lastname: Chatellier
authors.forename: B
authors.initials: B
authors.lastname: Beyssen
mesh_terms: D017130:Angioplasty / Q000009:adverse effects* / Q000295:instrumentation; D016893:Carotid Stenosis / Q000601:surgery*; D004691:Endarterectomy; D005374:Filtration / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology / Q000517:prevention & control; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D012449:Safety; D015607:Stents / Q000009:adverse effects*; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control*