X-linked lissencephaly in an Indian family.
Neuronal migration disorders are an important differential diagnosis to be considered in the evaluation of intractable epilepsy. Though the underlying causative factors which govern their development are many and varied, genetic factors have been found to be contributory in a few forms of these disorders. An X-linked association with lissencephaly has recently been discovered and there are a few families described till now with this entity.
Panda
S
S
Department of Neurology, All India Institute of Medical Sciences, New Delhi - 110029, India.
Tripathi
M
M
Jain
S
S
Sharma
P
P
D002540:Cerebral Cortex / Q000002:abnormalities*; D002675:Child, Preschool; D041321:Chromosomes, Human, X; D004827:Epilepsy / Q000235:genetics* / Q000473:pathology; D005192:Family Health; D008040:Genetic Linkage; D006801:Humans; D007194:India; D008607:Intellectual Disability / Q000235:genetics* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male