title: Inhibitory effects of 3-O-acyl-(+)-catechins on Epstein-Barr virus activation.
abstract: In the course of an exploratory investigation of antitumor-promoting catechins, 3-O-acyl-(+)-catechins of varying carbon lengths from C(4) to C(18) were assessed for inhibitory effects on the activation of the Epstein-Barr virus early antigen. Like 3-O-acyl-(-)-epigallocatechins, the (+)-catechin derivatives showed promising effects with the C-3 acyl chain of C(8)-C(11) carbon atoms.
authors.affiliation: Department of Biotechnology, Faculty of Engineering, Kansai University, Suita, Osaka, Japan. uesato@ipcku.kansai-u.ac.jp
authors.forename: Shinichi
authors.initials: S
authors.lastname: Uesato
authors.forename: Keisuke
authors.initials: K
authors.lastname: Taniuchi
authors.forename: Ayako
authors.initials: A
authors.lastname: Kumagai
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Nagaoka
authors.forename: Ryota
authors.initials: R
authors.lastname: Seto
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Hara
authors.forename: Harukuni
authors.initials: H
authors.lastname: Tokuda
authors.forename: Hoyoku
authors.initials: H
authors.lastname: Nishino
mesh_terms: D000956:Antigens, Viral / Q000378:metabolism*; D002392:Catechin / Q000737:chemistry* / Q000494:pharmacology*; D002460:Cell Line; D004854:Herpesvirus 4, Human / Q000187:drug effects* / Q000254:growth & development; D006801:Humans; D014775:Virus Activation / Q000187:drug effects*
chemical_list: D000956:Antigens, Viral; C033305:Epstein-Barr virus early antigen; D002392:Catechin