title: Concomitant use of sildenafil and a vacuum entrapment device for the treatment of erectile dysfunction.
abstract: OBJECTIVE
  Men not entirely satisfied with erectile function after separate use of sildenafil or a vacuum entrapment device (VED) are usually given more invasive alternatives. This prospective study was designed to evaluate the efficacy of concomitant use of sildenafil and a vacuum entrapment device in men not satisfied with erectile function while using each of these treatment modalities separately.
  
  
  METHODS
  A total of 161 patients suffering from erectile dysfunction for at least 6 months were evaluated and treated with 100 mg sildenafil and a VED each as monotherapy. The 41 patients not satisfied with erectile function while using either modality alone were treated with concomitant use of sildenafil and a VED. The International Index of Erectile Function and global assessment question about satisfaction from treatment were used to evaluate satisfaction before and after each treatment.
  
  
  RESULTS
  All 41 patients stated on the global assessment question that they had a greater level of satisfaction with the results of combined treatment than with each treatment alone (p <0.0001). Older (age greater than 60 years) participants reported better overall satisfaction. There was no correlation between treatment outcome and erectile dysfunction etiology or between satisfaction from treatments and the order in which they were given and the pretreatment scores for the International Index of Erectile Function domains.
  
  
  CONCLUSIONS
  Combined use of sildenafil and a VED may be offered to patients not satisfied when either treatment is used alone.
authors.affiliation: Department of Urology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
authors.forename: Juza
authors.initials: J
authors.lastname: Chen
authors.forename: Mario
authors.initials: M
authors.lastname: Sofer
authors.forename: Isaac
authors.initials: I
authors.lastname: Kaver
authors.forename: Haim
authors.initials: H
authors.lastname: Matzkin
authors.forename: Alexander
authors.initials: A
authors.lastname: Greenstein
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D007172:Erectile Dysfunction / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D011446:Prospective Studies; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014572:Urology / Q000295:instrumentation; D014618:Vacuum
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate