title: [Study of nausea and vomiting accompanying intravenous patient-controlled analgesia with fentanyl after cervical spine surgery].
abstract: BACKGROUND
  Serious side effects of postoperative analgesia with opioid drugs include nausea and vomiting.
  
  
  METHODS
  We investigated the effects of various factors (patient background, anesthesia duration, and intraoperative drug use) on the frequency and degree of postoperative nausea and vomiting (PONV) during the first 24 hours of intravenous patient-controlled analgesia (PCA) with fentanyl.
  
  
  RESULTS
  PONV occurred in 34% of the male patients and 68% of the female, and in 31% and 58% of smokers and non-smokers, respectively.
  
  
  CONCLUSIONS
  Consideration should be given to gender and smoking status prior to starting preventive antiemetic therapy using PCA with fentanyl following cervical spine surgery.
authors.affiliation: Department of Anesthesia and Intensive Care, Hiroshima City Asa Hospital, Hiroshima 730-0293.
authors.forename: Kenta
authors.initials: K
authors.lastname: Okamura
authors.forename: Michiyoshi
authors.initials: M
authors.lastname: Sanuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Fujii
authors.forename: Aki
authors.initials: A
authors.lastname: Matsunaga
mesh_terms: D000368:Aged; D000375:Aging; D016058:Analgesia, Patient-Controlled / Q000009:adverse effects*; D000932:Antiemetics / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000601:surgery*; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking
chemical_list: D000932:Antiemetics; D005283:Fentanyl