Three new hemoglobin variants with abnormal oxygen affinity: Hb Saratoga Springs [alpha40(C5)Lys --> Asn (alpha1)], Hb Santa Clara [beta97(FG4)His --> Asn], and Hb Sparta [beta103(G5)Phe --> Val].
Hoyer
James D
JD
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA. jhoyer@mayo.edu
Weinhold
John
J
Mailhot
Elisabeth
E
Alter
David
D
McCormick
Daniel J
DJ
Snow
Karen
K
Kubik
Kathleen S
KS
Holmes
Michael W
MW
Fairbanks
Virgil F
VF
D000328:Adult; D004252:DNA Mutational Analysis; D005260:Female; D014644:Genetic Variation; D006455:Hemoglobins, Abnormal / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D020125:Mutation, Missense; D010100:Oxygen / Q000378:metabolism*; D010108:Oxyhemoglobins / Q000737:chemistry / Q000235:genetics; D011086:Polycythemia / Q000209:etiology; D020836:Protein Structure, Quaternary; D017422:Sequence Analysis, DNA
D006455:Hemoglobins, Abnormal; D010108:Oxyhemoglobins; C487907:hemoglobin Santa Clara; C487906:hemoglobin Saratoga Springs; C487908:hemoglobin Sparta; D010100:Oxygen