title: Current concepts of the management of dental extractions for patients taking warfarin.
abstract: BACKGROUND
  Controversy has surrounded the correct management of patients therapeutically anticoagulated with warfarin who require dental extractions. The risk of bleeding must be weighed up against the risk of thromboembolism when deciding whether to interfere with a patient's warfarin regimen. An improved understanding of the importance of fibrinolytic mechanisms in the oral cavity has resulted in the development of various local measures to enable these patients to be treated on an outpatient basis.
  
  
  METHODS
  A review of the literature was undertaken. This was supplemented by the authors' clinical trials and extensive clinical experience with anticoagulated patients.
  
  
  RESULTS
  Various protocols for treating patients taking warfarin have been reviewed and summarized and an overview of the haemostatic and fibrinolytic systems is presented. A protocol for management of warfarinized patients requiring dental extractions in the outpatient setting is proposed.
  
  
  CONCLUSIONS
  Patients therapeutically anticoagulated with warfarin can be treated on an ambulatory basis, without interruption of their warfarin regimen provided appropriate local measures are used.
authors.affiliation: Oral and Maxillofacial Surgery Unit, Royal Adelaide Hospital, Adelaide Dental Hospital and The University of Adelaide, South Australia.
authors.forename: G
authors.initials: G
authors.lastname: Carter
authors.forename: A N
authors.initials: AN
authors.lastname: Goss
authors.forename: J
authors.initials: J
authors.lastname: Lloyd
authors.forename: R
authors.initials: R
authors.lastname: Tocchetti
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D017742:Dental Care for Chronically Ill; D006801:Humans; D006472:Oral Hemorrhage / Q000517:prevention & control; D012307:Risk Factors; D013923:Thromboembolism / Q000517:prevention & control; D014081:Tooth Extraction; D014859:Warfarin / Q000627:therapeutic use*
chemical_list: D000925:Anticoagulants; D014859:Warfarin