Three-dimensional conformal radiation therapy (3D-CRT) for early-stage non-small-cell lung cancer.
The standard treatment for early-stage non-small-cell lung cancer is surgical resection. However, many patients are inoperable due to medical comorbidities. Thirty-two medically inoperable patients with early-stage non-small-cell lung cancer were treated with 3-dimensional conformal radiation therapy between January 1991 and December 2000. The median dose was 70.2 Gy, and the median follow-up time in survivors was 30 months. The 2-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 54%, and 57%, respectively. The 5-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 33%, and 39%, respectively. This report suggests that local control is improved with high-dose conformal radiation therapy when compared to other institutions' retrospective experiences.
Rosenzweig
K E
KE
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. rosenzwk@mskcc.org
Dladla
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N
Schindelheim
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R
Sim
S E
SE
Braban
L E
LE
Venkataraman
E S
ES
Leibel
S A
SA