title: Esophageal carcinoma with tracheal stenosis due to tumor invasion and long survival after chemoradiotherapy.
abstract: For patients who have esophageal carcinoma with tracheal invasion surgery is usually not indicated because operative complications are considerable and the prognosis is poor. We experienced complete regression of a large esophageal carcinoma with tracheal stenosis due to tumor invasion without tracheo-esophageal fistula. Irradiation of 68 Gy was delivered to a long T field from the neck to the lower thoracic esophagus, and was combined with chemotherapy using cisplatin and 5-fluorouracil. The tumor decreased markedly in size and the tracheal stenosis resolved. The patient has survived for 4 years, although second primary early esophageal carcinoma and hypopharyngeal carcinoma were detected 2 years after his initial chemoradiotherapy. Although the prognosis of advanced esophageal carcinoma with invasion of other organs is usually poor, the effect of chemoradiotherapy can sometimes be dramatic and a good result can be achieved in such patients.
authors.affiliation: Department of Surgery, Toranomon Hospital, Tokyo, Japan. yoshihirokinoshita@nifty.com
authors.forename: Y
authors.initials: Y
authors.lastname: Kinoshita
authors.forename: H
authors.initials: H
authors.lastname: Udagawa
authors.forename: K
authors.initials: K
authors.lastname: Tsutsumi
authors.forename: M
authors.initials: M
authors.lastname: Ueno
authors.forename: S
authors.initials: S
authors.lastname: Mine
authors.forename: S
authors.initials: S
authors.lastname: Hukuda
authors.forename: K
authors.initials: K
authors.lastname: Sasaki
authors.forename: S
authors.initials: S
authors.lastname: Matoba
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: T
authors.initials: T
authors.lastname: Sawada
authors.forename: G
authors.initials: G
authors.lastname: Watanabe
mesh_terms: D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012074:Remission Induction; D017741:Survivors; D013997:Time Factors; D014135:Tracheal Stenosis / Q000209:etiology*