Topical calcipotriol ointment in the treatment of morphea.
A 5-year-old girl presented with a 2-month history of an indurated hypopigmented, atrophic plaque of biopsy-documented morphea over the right hip area. Previous treatment with 0,1% betamethasone valerate cream twice a day for 3 months failed to improve the lesion. She was treated with calcipotriol ointment twice daily, with nightly occlusion to the plaque for 9 months, and this resulted in resolution. No side effects were noted.
Tay
Y K
YK
National Skin Centre, and Changi General Hospital, 2 Simei Street 3, Singapore 529889. yong_kwang_tay@cgh.com.sg
D000287:Administration, Topical; D001707:Biopsy, Needle; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D012594:Scleroderma, Localized / Q000188:drug therapy* / Q000473:pathology*; D012720:Severity of Illness Index; D016896:Treatment Outcome
C055085:calcipotriene; D002117:Calcitriol