Five highly informative X-chromosomal STRs in Koreans.
The five X-chromosomal short tandem repeats (STRs) GATA172D05, HPRTB, DXS8377, DXS101 and HumARA were analyzed in 150 males and 150 females from Korea. Markers were amplified in a quadruplex and a monoplex PCR reaction with fluorescently labeled primers. For accurate and reproducible STR typing, sequenced allelic ladders were constructed and a Genotyper macro was programmed. Some differences were found on comparing the allele frequencies of Koreans with those of other populations in DXS8377, DXS101 and HumARA. The forensic efficiency parameters showed that the five X-linked STRs are highly informative for forensic application in Koreans.
Shin
Kyoung-Jin
KJ
Department of Forensic Medicine, College of Medicine, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752 Seoul, Korea. kjshin@yumc.yonsei.ac.kr
Kwon
Byung-Ki
BK
Lee
Sang-Seob
SS
Yoo
Ji-Eun
JE
Park
Myung Jin
MJ
Chung
Ukhee
U
Lee
Hwan Young
HY
Han
Gil-Ro
GR
Choi
Jong-Hoon
JH
Kim
Chong-Youl
CY
D041321:Chromosomes, Human, X / Q000235:genetics*; D005260:Female; D005554:Forensic Medicine; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007723:Korea; D008297:Male; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences