title: [Preparation of fiber complexes and its role in lipid peroxidation].
abstract: This study was designed to prepare the artificial fiber complexes and examine its role in lipid peroxidation in comparison with other fibers. Sixty-four healthy, female Wistar rats (50-80 g) were randomly divided into eight groups based on body weight. All seven kinds of DF (cellulose--group B, pectin--group C, sodium alginate--group D, cellulose-pectin complex--group E, cellulose-sodium alginate complex--group F, cellulose-pectin mixture--group G, cellulose-sodium alginate mixture--group H) were given at a level of 10% in the diet fed on a lipid-rich diet. The control group (group A) was fed on a lipid-rich diet alone without DF. After eight weeks, the effect on growth and development, lipid metabolism and lipid peroxidation in rats were studied. The results showed that: 1. Seven kinds of DF did not affect the growth and development of the experimental rats. 2. Seven kinds of DF all can increase serum superoxide dismutase (SOD) and glutathione peroxidase (GsH-Px) activities and reduce malondiadehyde (MDA) content (except group B and D). Erythrocyte membrane fluidity was significantly increased in DF groups, and fiber complex groups were most effective. 3. The fecal weight and fat contents in all DF groups were significantly higher than that in control group, especially for fiber mixture and complex groups. It is concluded that all these kinds of DF have the effect of reducing lipid peroxidation to some extent in rats, and fiber complexes might be the most effective.
authors.affiliation: Department of Nutrition, Medical College of Qingdao University, Qingdao 266021, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Song
authors.forename: Zongjun
authors.initials: Z
authors.lastname: Yang
mesh_terms: D000464:Alginates / Q000008:administration & dosage; D000818:Animals; D002482:Cellulose / Q000008:administration & dosage; D004043:Dietary Fiber / Q000494:pharmacology*; D005260:Female; D020723:Glucuronic Acid / Q000008:administration & dosage; D005979:Glutathione Peroxidase / Q000378:metabolism; D006603:Hexuronic Acids / Q000008:administration & dosage; D015227:Lipid Peroxidation / Q000187:drug effects*; D008315:Malondialdehyde / Q000378:metabolism; D010368:Pectins / Q000008:administration & dosage; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D000464:Alginates; D004043:Dietary Fiber; D006603:Hexuronic Acids; D008315:Malondialdehyde; D010368:Pectins; D020723:Glucuronic Acid; D002482:Cellulose; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase