Mycotic aneurysm of the popliteal artery as a complication of intravesical BCG therapy for superficial bladder cancer. Case report and literature review.
A 67-year-old man was treated with maintenance intravesical BCG for superficial bladder cancer. As a culture-proven complication of this therapy, he developed general malaise, high fever, granulomatous hepatitis and a mycotic aneurysm in his left knee. All complications were treated successfully with antituberculous therapy. No vascular surgery was necessary. This case report again stresses the necessity to recognise complications of BCG treatment and to start adequate therapy as soon as possible.
Witjes
J A
JA
Department of Urology, University Medical Centre St. Radboud, Nijmegen, The Netherlands. F.Witjes@uro.azn.nl
Vriesema
J L J
JL
Brinkman
K
K
Bootsma
G
G
Barentsz
J O
JO
D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D000283:Administration, Intravesical; D000368:Aged; D000785:Aneurysm, Infected / Q000209:etiology*; D001500:BCG Vaccine / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011150:Popliteal Artery; D014381:Tuberculosis, Cardiovascular / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine