Successful management of a pregnant woman with heterozygous protein C deficiency using activated protein C concentrate.
Heterozygous protein C deficiency frequently causes deep vein thrombosis during pregnancy. We report the successful management of delivery using activated protein C concentrate in a patient with heterozygous protein C deficiency, who developed deep vein thrombosis in mid gestation.
Sekiyama
Kentaroh
K
Department of Gynecology and Obstetrics, Clinical Sciences for Pathological Organs, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Itoh
Hiroaki
H
Sagawa
Norimasa
N
Tatsumi
Keiji
K
Yura
Shigeo
S
Takayama
Hiroshi
H
Fujii
Shingo
S
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D005268:Femoral Vein; D006579:Heterozygote; D006801:Humans; D011152:Popliteal Vein; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000209:etiology; D011486:Protein C / Q000627:therapeutic use*; D020151:Protein C Deficiency / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000209:etiology
D000925:Anticoagulants; D011486:Protein C