[Psychophysiologic disorders in patients with functional disorders of upper sections of the gastrointestinal tract and with gastroesophageal reflux disease].
The features of the psychovegetative status in patients with functional disorders of the esophagus and stomach (FD) and gastroesophageal reflux disease (GERD) are investigated. The methods included clinical, instrumental and psychometric examination. The patients of both groups had similar vegetative abnormalities and a tendency towards the growth of depression and anxiety parameters, did not differ in psychosocial factors, and had a wide range of psychovegetative abnormalities (PA). Lump in the throat, heartburn, epigastralgia (p < 0.01), depression, actual anxiety, alexitymia and vegetative disorders decreased in both groups (p < 0.05) after treatment with citalopram (20 mg per day) during 2 months. So PA are revealed in patients with FD and GERD, and citalopram reduces psychovegetative and GIT disorders.
Rykova
S M
SM
I.M. Sechenov Moscow Medical Academy.
Pogromov
A P
AP
Diukova
G M
GM
Veĭn
A M
AM
D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D015283:Citalopram / Q000627:therapeutic use; D004935:Esophageal Diseases / Q000150:complications* / Q000503:physiopathology* / Q000523:psychology; D005764:Gastroesophageal Reflux / Q000150:complications*; D005767:Gastrointestinal Diseases / Q000150:complications* / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008297:Male; D011602:Psychophysiologic Disorders / Q000188:drug therapy / Q000503:physiopathology*; D013997:Time Factors; D016896:Treatment Outcome
D018687:Antidepressive Agents, Second-Generation; D015283:Citalopram