title: Morphological and biochemical modifications induced by a static magnetic field on Fusarium culmorum.
abstract: The effects of the exposure to a static magnetic field (sMF) of 0.3 +/- 0.03 T on the Fusarium culmorum were investigated in vitro. sMF inhibition of mycelia growth was accompanied by morphological and biochemical changes. Fungal conidia germination and cell viability were also reduced. We provide evidence of the influence of sMF on Ca(2+)-dependent signal transduction pathways involved in conidia germination. Perturbation of these pathways by adding different compounds (i.e. CaCl(2), phorbol 12-myristate 13-acetate, neomycin, EGTA, LiCl) to the medium, suggested that exposed conidia are unable to mobilise calcium from intracellular stores and that the hindered mechanism may be IP(3)-dependent.
authors.affiliation: Istituto di Chimica Biologica Giorgio Fornaini, Università degli Studi di Urbino, via Saffi 2, 6102, Urbino, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Albertini
authors.forename: Augusto
authors.initials: A
authors.lastname: Accorsi
authors.forename: Barbara
authors.initials: B
authors.lastname: Citterio
authors.forename: Sabrina
authors.initials: S
authors.lastname: Burattini
authors.forename: Maria Piera
authors.initials: MP
authors.lastname: Piacentini
authors.forename: Francesco
authors.initials: F
authors.lastname: Uguccioni
authors.forename: Elena
authors.initials: E
authors.lastname: Piatti
mesh_terms: D002122:Calcium Chloride / Q000494:pharmacology; D004533:Egtazic Acid / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects / Q000254:growth & development*; D018021:Lithium Chloride / Q000494:pharmacology; D008280:Magnetics; D025282:Mycelium / Q000187:drug effects / Q000254:growth & development; D009355:Neomycin / Q000494:pharmacology; D013755:Tetradecanoylphorbol Acetate / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D004533:Egtazic Acid; C016658:phorbolol myristate acetate; D018021:Lithium Chloride; D009355:Neomycin; D002122:Calcium Chloride; D013755:Tetradecanoylphorbol Acetate