title: Invasive micropapillary carcinoma of the breast with minimal regional lymph node metastasis regardless of the huge size: report of a case.
abstract: We present a 38-year-old premenopausal Japanese woman with invasive micropapillary carcinoma (IMC) of the left breast with minimal lymph node metastasis despite a huge size. The patient noticed a left breast mass and a bloody nipple discharge 2 years before admission. On admission, physical examination revealed a huge, elastic hard mass with skin ulcer 12x12 cm in diameter occupying the entire left breast. The patient underwent modified radical mastectomy with level III lymph node dissection, and the defect was reconstructed with a vertical rectus abdominis myocutaneous flap. Histopathologically, IMC comprised about 60% of the tumor, admixed with papillotubular and mucinous carcinoma. Only one of twenty-five lymph nodes had tumor metastasis. The patient remains well 8 months postoperatively without any signs of recurrence.
authors.affiliation: Department of Surgery, Aso Iizuka Hospital, 3-83 Yoshiomachi, Iizuka, Fukuoka 820-8505, Japan. takiyoshih1@aih-net.com
authors.forename: Takashi
authors.initials: T
authors.lastname: Akiyoshi
authors.forename: Takashi
authors.initials: T
authors.lastname: Nagaie
authors.forename: Masanori
authors.initials: M
authors.lastname: Tokunaga
authors.forename: Mmasaki
authors.initials: M
authors.lastname: Tajima
authors.forename: Makoto
authors.initials: M
authors.lastname: Morita
authors.forename: Akio
authors.initials: A
authors.lastname: Nakatsuka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Taga
authors.forename: Shigeki
authors.initials: S
authors.lastname: Wakiyama
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ikebe
authors.forename: Kozo
authors.initials: K
authors.lastname: Nakanishi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Taisuke
authors.initials: T
authors.lastname: Toyomasu
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nakanishi
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015411:Mastectomy, Modified Radical; D009361:Neoplasm Invasiveness; D013524:Surgical Flaps