Postoperative communicating hydrocephalus in patients with supratentorial malignant glioma.
Postoperative communicating hydrocephalus in adult patients with supratentorial malignant glioma is a relatively uncommon condition that occurs months after the initial operation of tumor excision. It occurred in only five of 50 consecutive cases treated in our department during the past 10 years. The hydrocephalus appeared to be attributable to leptomeningeal dissemination of tumor cells and subsequent impairment in cerebrospinal fluid (CSF) absorption. The tumors were located adjacent to the lateral ventricles in all five patients, and the proximity of the tumor to the cerebral ventricles may have facilitated dissemination of the tumor cells into the CSF space, resulting in hydrocephalus. The hydrocephalus was treated by a shunt surgery in all five cases, and the symptoms temporarily improved. None of the five patients experienced shunt malfunction or abdominal symptoms attributable to metastasis to the peritoneal cavity, and all five patients died of regrowth of the intracranial tumor or of pneumonia.
Inamasu
Joji
J
Department of Neurosurgery, National Tokyo Medical Center, Higashigaoka 2-5-1, Meguro-ku, Tokyo 152-8902, Japan. ginamasu@aol.com
Nakamura
Yoshiki
Y
Saito
Ryoichi
R
Kuroshima
Yoshiaki
Y
Mayanagi
Keita
K
Orii
Maaya
M
Ichikizaki
Kiyoshi
K
D000368:Aged; D001254:Astrocytoma / Q000175:diagnosis / Q000601:surgery*; D002555:Cerebrospinal Fluid / Q000166:cytology; D005909:Glioblastoma / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D008578:Meninges / Q000473:pathology; D008875:Middle Aged; D018365:Neoplasm, Residual / Q000175:diagnosis / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D011379:Prognosis; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D015173:Supratentorial Neoplasms / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt