title: C-reactive protein as a novel biomarker. Reactant can flag atherosclerosis and help predict cardiac events.
abstract: C-reactive protein (CRP) is a relatively nonspecific marker of inflammation. However, it can be used to monitor the severity and progression of some well-defined cardiovascular diseases. For example, it can predict serious events in patients with coronary artery disease (CAD) who are hospitalized with acute coronary syndrome, myocardial infarction (MI), or advanced peripheral vascular disease. In this article, the authors review the role of CRP in the diagnosis, monitoring, and treatment of various forms of ischemic and inflammatory cardiovascular disease.
authors.affiliation: Division of Allergy and Immunology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, PO Box 70622, Johnson City, TN 37614-1709, USA.
authors.forename: Nader
authors.initials: N
authors.lastname: Elgharib
authors.forename: David S
authors.initials: DS
authors.lastname: Chi
authors.forename: Walid
authors.initials: W
authors.lastname: Younis
authors.forename: Salim
authors.initials: S
authors.lastname: Wehbe
authors.forename: Guha
authors.initials: G
authors.lastname: Krishnaswamy
mesh_terms: D001161:Arteriosclerosis / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000097:blood* / Q000175:diagnosis; D005080:Exercise Test; D006801:Humans; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein