title: Coronally positioned flap with or without enamel matrix protein derivative for the treatment of gingival recessions.
abstract: OBJECTIVE
  To evaluate, histometrically, the healing of gingival recessions treated by coronally positioned flaps associated with enamel matrix protein derivative (EMD-Group) and to compare it to that obtained with coronally positioned flaps alone (CPF-Group).
  
  
  METHODS
  Five mongrel dogs were used. Gingival recessions were surgically created on the buccal aspect of the upper cuspids. The defects (5 x 7 mm) were exposed to plaque accumulation for 3 months. After a preparation period, the contralateral defects were randomly assigned to each group. After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, length of epithelium, new connective tissue attachment and new bone.
  
  
  RESULTS
  The gingival recession was -0.1 +/- 0.2 mm for the EMD-Group and -0.8 +/- 1.3 mm for the CPF-Group (P = 0.17). The extension of the epithelium was 1.2 +/- 1.0 mm for the EMD-Group and 1.3 +/- 0.7 mm for the CPF-Group (P = 0.89). The new connective tissue attachment was 4.8 +/- 0.7 in the EMD-Group and 4.0 +/- 1.4 in the CPF-Group (P = 0.22). The new bone was 0.1 +/- 1.8 mm and -0.5 +/- 1.4 mm in the EMD-Group and CPF-Group, respectively (P = 0.50). Histologically, the defect coverage observed was 98.2% for the EMD-Group and 85.8% for the CPF-Group.
authors.affiliation: Division of Periodontics, School of Dentistry at Piracicaba, University of Campinas, Piracicaba, SP, Brazil. easallum@fop.unicamp.br
authors.forename: Enilson A
authors.initials: EA
authors.lastname: Sallum
authors.forename: Marcio Z
authors.initials: MZ
authors.lastname: Casati
authors.forename: Raul G
authors.initials: RG
authors.lastname: Caffesse
authors.forename: Leticia Perecin
authors.initials: LP
authors.lastname: Funis
authors.forename: Francisco H
authors.initials: FH
authors.lastname: Nociti Júnior
authors.forename: Antônio W
authors.initials: AW
authors.lastname: Sallum
mesh_terms: D000134:Acid Etching, Dental; D000539:Alveolar Process / Q000473:pathology; D000818:Animals; D003238:Connective Tissue / Q000473:pathology; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004285:Dogs; D004846:Epithelial Attachment / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005260:Female; D005889:Gingival Recession / Q000601:surgery*; D011897:Random Allocation; D018709:Statistics, Nonparametric; D013357:Subgingival Curettage; D013524:Surgical Flaps; D013997:Time Factors; D014945:Wound Healing
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins