title: Patients undergoing surgical resection of primary brain tumors should receive pharmacologic venous thromboprophylaxis.
abstract: A 58-year-old woman presents with headache, mental status changes, and new-onset generalized seizures. MRI of the brain reveals a frontoparietal enhancing mass lesion suggestive of glioblastoma multiforme. Craniotomy for diagnosis, debulking, and likely placement of chemotherapy-impregnated wafers is planned. Venous thromboprophylaxis is prescribed.
authors.affiliation: Section of Vascular Medicine, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH, USA. begelms@ccf.org
authors.forename: Susan M
authors.initials: SM
authors.lastname: Begelman
authors.forename: David
authors.initials: D
authors.lastname: Green
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D003399:Craniotomy; D016503:Drug Delivery Systems; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D005909:Glioblastoma / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D006801:Humans; D007430:Intraoperative Care; D020246:Venous Thrombosis / Q000517:prevention & control*
chemical_list: D005343:Fibrinolytic Agents