What keeps serum calcium levels stable?
Many body functions require that serum calcium levels remain stable over time. This stability is provided by cooperation among three organs: two effectors, the bone and the kidney, which control calcium movements into and out of the extracellular compartment, and the parathyroid glands, which produce and release parathyroid hormone (PTH). PTH acts on the bone and renal tubule. Provided the amount released is appropriate, this keeps extracellular calcium levels stable.
Houillier
Pascal
P
Department of Physiology and Radioisotopes, European Georges Pompidou Teaching Hospital, Paris VI University, Inserm unit 356, 20, rue Leblanc, 75015 Paris, France. pascal.houillier@egp.ap-hop-paris.fr
Nicolet-Barousse
Laurence
L
Maruani
Gérard
G
Paillard
Michel
M
D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000032:analysis / Q000378:metabolism*; D020013:Calcium Signaling / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000378:metabolism; D010280:Parathyroid Glands / Q000378:metabolism; D010281:Parathyroid Hormone / Q000378:metabolism*; D044169:Receptors, Calcium-Sensing / Q000378:metabolism; D014882:Water-Electrolyte Balance / Q000502:physiology*
C095550:CASR protein, human; D010281:Parathyroid Hormone; D044169:Receptors, Calcium-Sensing; D002118:Calcium