title: A controlled study of sleep related disordered breathing in obese children.
abstract: BACKGROUND
  Unlike the adult sleep related disordered breathing (SDB) patients who are typically obese, the relation between obesity and childhood SDB is not clear.
  
  
  OBJECTIVE
  To investigate whether obese children are more at risk of obstructive SDB when compared to normal population, and whether this risk is potentiated by the presence of pharyngeal lymphoid tissue.
  
  
  METHODS
  Forty six obese children (age 10.8 (SD 2.3) years; BMI 27.4 (SD 5.1)), and 44 sex and age matched normal weight children (age 11.7 (SD 2.1) years; BMI 18 (SD 1.8)) were studied. All children underwent a set of physical examinations (including the upper airways) and sleep studies.
  
  
  RESULTS
  The obese children were different from the normal weight children in terms of type (predominantly obstructive), frequency, and severity of respiratory disturbances. Depending on the criteria used, 26% or 32.6% of obese children had SDB; 2.3% of normal controls had OAI > or =1 and 4.5% had RDI > or =5. Presence of SDB was related to presence of tonsils (size >2; range 0-4) (OR 12.67, 95% CI 2.14 to 75.17) and BMI (OR 1.20, 95% CI 1.08 to 1.33).
  
  
  CONCLUSIONS
  Results suggest that obese children are at increased risk of obstructive SDB; the presence of any pharyngeal lymphoid tissue enlargement in obese children should therefore be aggressively managed.
authors.affiliation: Department of Psychiatry, Prince of Wales and Shatin Hospital, Shatin, The Chinese University of Hong Kong, Hong Kong SAR, China. ykwing@cuhk.edu.hk
authors.forename: Y K
authors.initials: YK
authors.lastname: Wing
authors.forename: S H
authors.initials: SH
authors.lastname: Hui
authors.forename: W M
authors.initials: WM
authors.lastname: Pak
authors.forename: C K
authors.initials: CK
authors.lastname: Ho
authors.forename: A
authors.initials: A
authors.lastname: Cheung
authors.forename: A M
authors.initials: AM
authors.lastname: Li
authors.forename: T F
authors.initials: TF
authors.lastname: Fok
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications* / Q000473:pathology; D014066:Palatine Tonsil; D010608:Pharyngeal Diseases / Q000473:pathology; D012044:Regression Analysis; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000473:pathology; D009626:Terminology as Topic