[Diabetes and drug treatment of hypertension].
In hypertensive diabetic patients, reducing blood pressure is among the best evaluated and most effective interventions for lowering mortality and morbidity. First line antihypertensive agents are: chlorthalidone or other thiazide-type diuretics, beta-blockers and ACE-inhibitors. In type 2 diabetic patients with left ventricular hypertrophy, the ARB Cosaar has been proven to be effective. To achieve an effective blood pressure reduction, a combination of different antihypertensive agents is necessary for most patients. Specially structured patient education programmes are another effective means of achieving this goal.
Siebenhofer
Andrea
A
Diabetes- und Stoffwechselambulanz, Medizinische Universitätsklinik Graz, Auenbruggerplatz 15, 8036 Graz, Osterreich. andrea.siebenhofer@kfuni-graz.at
Horvath
Karl
K
Kraly
Barbara
B
Plank
Johannes
J
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001581:Benzothiadiazines; D002423:Cause of Death; D002752:Chlorthalidone / Q000009:adverse effects / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000401:mortality; D004232:Diuretics; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000401:mortality; D016032:Randomized Controlled Trials as Topic; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D015996:Survival Rate
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D002752:Chlorthalidone