Crystallization and preliminary X-ray diffraction studies of DNA decamer d(CCAGGCCTGG) complexed with cobalt(III)-pepleomycin.
Crystals of the self-complementary oligonucleotide d(CCAGGCCTGG) [Heinemann & Alings (1989), J. Mol. Biol. 210, 369-381] complexed with the hydroperoxide of cobalt-pepleomycin (CoPEP) were obtained by the hanging-drop vapour-diffusion method at 298 K. An X-ray diffraction data set was collected to 2.8 A at 100 K. The crystal belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.52, b = 59.88, c = 72.93 A.
Yaguma
Kouji
K
Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Matsumoto
Osamu
O
Guan
Le Luo
LL
Kawano
Yoshiaki
Y
Kamiya
Nobuo
N
Tsujimoto
Gozoh
G
Sugiura
Yukio
Y
D000903:Antibiotics, Antineoplastic / Q000737:chemistry*; D003035:Cobalt / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D017663:Peplomycin / Q000737:chemistry*
D000903:Antibiotics, Antineoplastic; D009841:Oligonucleotides; D003035:Cobalt; D017663:Peplomycin; D004247:DNA