A case of multiorgan failure following interruption of antiretroviral treatment.
Reported here is an exceptional case of acute retroviral syndrome resembling septic shock that occurred in a chronic HIV-infected patient shortly following planned interruption of antiretroviral treatment. The therapeutic strategy, which is aimed at improving the immunological control of HIV infection, can therefore be deleterious in chronically infected patients and should be avoided outside of closely monitored clinical trials.
Crespo
M
M
Infectious Diseases Service, Hospital Vall d'Hebrón, Universitat Autónoma de Barcelona, Paseo Vall d'Hebrón 119-129, 08035 Barcelona, Spain. mcrespo@hg.vhebron.es
Paradiñeiro
J C
JC
Ribera
E
E
Ruiz
I
I
Falcó
V
V
Lopez-Quiñones
J
J
Ocaña
I
I
Pahissa
A
A
D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D018450:Disease Progression; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008134:Long-Term Care; D009102:Multiple Organ Failure / Q000209:etiology* / Q000503:physiopathology; D018570:Risk Assessment; D019562:Viral Load
D019380:Anti-HIV Agents