Behavioural and emotional disturbances in people with Prader-Willi Syndrome.
BACKGROUND
The study of the behaviour profile in subjects with Prader-Willi Syndrome (PWS).


METHODS
A total of fifty-eight 3- to 29-year-old subjects with PWS were studied using a standardized parent report of behavioural and emotional disturbances.


RESULTS
There was an increase of behavioural and emotional disturbances for the adolescent and young adult age range, whereas gender and intelligence were not significant. Increasing body mass index (BMI) was also associated with more behavioural and emotional disturbances. There was no significant relation between genetic status and behavioural abnormalities.


CONCLUSIONS
This systematic study supports single case observations of a heightened psychiatric vulnerability of adolescent and young adult PWS subjects.
Steinhausen
H-C
HC
Department of Child and Adolescent Psychiatry, University of Zurich, Switzerland. steinh@kjpd.unizh.ch
Eiholzer
U
U
Hauffa
B P
BP
Malin
Z
Z
D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology / Q000209:etiology*; D019964:Mood Disorders / Q000453:epidemiology / Q000209:etiology*; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology; D011218:Prader-Willi Syndrome / Q000523:psychology*; D015995:Prevalence