Leishmania and HIV co-infection: dermatological manifestations.
Leishmania species can cause a wide spectrum of cutaneous disease in HIV-positive patients: asymptomatic, localized cutaneous, mucosal, muco-cutaneous, diffuse cutaneous or post-kala-azar leishmaniasis. In such cases, which are usually severely immunocompromised, the leishmanial parasites reach the skin of the human host by dissemination after either a new infection (resulting from the bite of infected sandfly or, probably, the sharing of contaminated syringes by intravenous-drug users) or the re-activation of a latent infection. Recent experience and past observations on the dermatology of leishmaniasis in those with Leishmania/HIV co-infection are reviewed here.
Puig
L
L
Departamento de Dermatología, Hospital de la Santa Creu I Sant Pau, Avenida de Sant Antoni Maria Claret, 167, 08025 Barcelona, Spain. lpuigs@meditex.es
Pradinaud
R
R
D017088:AIDS-Related Opportunistic Infections / Q000469:parasitology*; D000818:Animals; D015897:Comorbidity; D006801:Humans; D007121:Immunocompetence / Q000502:physiology; D007303:Insect Vectors / Q000469:parasitology; D016773:Leishmaniasis, Cutaneous / Q000469:parasitology*; D007897:Leishmaniasis, Mucocutaneous / Q000469:parasitology; D016485:Needle Sharing / Q000009:adverse effects; D011576:Psychodidae / Q000469:parasitology; D012867:Skin / Q000469:parasitology