title: Breast cancer with endocrine differentiation: report of two cases showing different histologic patterns.
abstract: We report two cases of breast cancer with endocrine differentiation. Case 1 was a 56-year-old woman with a 2-cm tumor in the upper outer quadrant of the right breast and right axillary lymphadenopathy. Excisional biopsy suggested carcinoma and we performed breast-conserving surgery with lymph node dissection. Histologic examination revealed breast cancer with endocrine differentiation resembling small cell carcinoma of the lung, with one nodal metastasis. Case 2 was a 71-year-old woman with a 2.5-cm tumor in the upper outer quadrant of the right breast. Aspiration cytology suggested carcinoma and we performed mastectomy with lymph node dissection. Histologic examination revealed a carcinoid tumor, as one of the breast cancers with endocrine differentiation, but no nodal metastasis. The two patients are now disease-free 26 and 12 months after surgery, respectively.
authors.affiliation: Department of Surgery, Toyama Prefectural Central Hospital, Toyama, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ajisaka
authors.forename: Kiichi
authors.initials: K
authors.lastname: Maeda
authors.forename: Atsuo
authors.initials: A
authors.lastname: Miwa
authors.forename: Katsuya
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D002277:Carcinoma / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D004703:Endocrine System / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged