Skene's gland adenocarcinoma resembling prostatic adenocarcinoma.
An 88-year-old woman presented with gross hematuria and a 3-cm periurethral mass. Biopsy revealed an adenocarcinoma resembling prostatic adenocarcinoma; the tumor cells were positive for keratin and prostate-specific antigen. The serum level of prostate-specific antigen was elevated; the carcinoembryonic antigen and CA-125 serum levels were normal. One year after external beam radiotherapy, the patient is without evidence of disease. This is the sixth case of a urethral prostatic-type adenocarcinoma, tumors that are most likely of Skene's gland origin.
Pongtippan
Atcharaporn
A
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.
Malpica
Anais
A
Levenback
Charles
C
Deavers
Michael T
MT
Silva
Elvio G
EG
D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000378:metabolism / Q000473:pathology*; D014523:Urethral Neoplasms / Q000378:metabolism / Q000473:pathology*
D017430:Prostate-Specific Antigen