title: Preparation and evaluation of sulfur-containing metal chelators.
abstract: With a view to probe the structure and function of G-protein coupled receptors the synthesis of functionalized 8-mercaptoquinoline derivatives and 2-(2-pyridyl)thiophenol was achieved. A fluorescence-based method for determining the affinity of these metal chelators toward zinc ions was developed.
authors.affiliation: Karolinska Institute, Center for Nutrition and Toxicology, Novum Research Park, SE-141 57 Huddinge, Sweden.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Clavier
authors.forename: Oystein
authors.initials: O
authors.lastname: Rist
authors.forename: Stina
authors.initials: S
authors.lastname: Hansen
authors.forename: Lars-Ole
authors.initials: LO
authors.lastname: Gerlach
authors.forename: Thomas
authors.initials: T
authors.lastname: Högberg
authors.forename: Jan
authors.initials: J
authors.lastname: Bergman