Benign focal epilepsy with onset in infancy in a patient with 18q-syndrome.
METHODS
The 18q-syndrome is sometimes associated with epilepsy. We report a child with a 18q deletion who showed the typical manifestations of the syndrome. In addition, she had benign focal epilepsy with onset in infancy characterized by complex partial seizures with a frequency from 1 to 20 per day. This type of epilepsy is a rare condition and this is the first report of benign focal epilepsy with onset in infancy in a child with 18q-syndrome. The EEGs performed during sleep showed low-voltage spikes over the fronto-central region of the left hemisphere. The magnetic resonance imaging of the brain was normal.


CONCLUSIONS
In conclusion, benign focal epilepsy with onset in infancy could be a condition associated with 18q-syndrome.
Verrotti
Alberto
A
Section of Pediatrics, Department of Medicine, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy. averrott@obelix.unich.it
Trotta
Daniela
D
Salladini
Carmela
C
di Corcia
Giovanna
G
Chiarelli
Francesco
F
D002887:Chromosomes, Human, Pair 18 / Q000235:genetics*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications* / Q000235:genetics*; D005260:Female; D017353:Gene Deletion; D006801:Humans; D008279:Magnetic Resonance Imaging; D013577:Syndrome