title: Determinants of quality of life in first-episode psychosis.
abstract: OBJECTIVE
  To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP).
  
  
  METHODS
  Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis.
  
  
  RESULTS
  Patients presented with varying levels of QOL on different domains. The level of 'general satisfaction' was related to age of onset and social premorbid adjustment; 'weighted index of QOL' to social premorbid adjustment and inversely to educational premorbid adjustment; 'social relations' inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; 'psychological well-being' inversely to depression and educational premorbid adjustment; 'activities of daily living' to social premorbid adjustment and inversely to negative symptoms; and 'outlook on symptoms' to level of depression.
  
  
  CONCLUSIONS
  Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.
authors.affiliation: McGill University, Montreal, Quebec, Canada. ashok.malla@douglas.mcgill.ca
authors.forename: A K
authors.initials: AK
authors.lastname: Malla
authors.forename: R M G
authors.initials: RM
authors.lastname: Norman
authors.forename: T S
authors.initials: TS
authors.lastname: McLean
authors.forename: C
authors.initials: C
authors.lastname: MacDonald
authors.forename: E
authors.initials: E
authors.lastname: McIntosh
authors.forename: F
authors.initials: F
authors.lastname: Dean-Lashley
authors.forename: J
authors.initials: J
authors.lastname: Lynch
authors.forename: D
authors.initials: D
authors.lastname: Scholten
authors.forename: R
authors.initials: R
authors.lastname: Ahmed
mesh_terms: D000328:Adult; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation; D011788:Quality of Life; D012044:Regression Analysis; D012917:Social Adjustment; D011795:Surveys and Questionnaires