Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks' gestation.
The findings are reported of a retrospective study of 207 women undergoing medical evacuation of the uterus for first trimester miscarriage, using mifepristone followed by a single dose of oral misoprostol. All women had the diagnosis confirmed by ultrasonography. Complete medical evacuation was achieved in 88% of cases. The success rate and incidence of complications was observed to be the same regardless of whether gestation was below or above 9 weeks. The number of cases in which antibiotic treatment for presumed pelvic infection was prescribed was 3%. The incidence of anaemia requiring blood transfusion was 3%.
Greenland
Hugh
H
Royal Bolton Hospital, Farnworth, Bolton, UK. hughgreenland@doctors.org.uk
Ogunbiyi
I
I
Bugg
George
G
Tasker
Margaret
M
D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000021:Abortifacient Agents, Steroidal / Q000627:therapeutic use*; D000022:Abortion, Spontaneous / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D000328:Adult; D005260:Female; D006767:Hospitals, District; D006769:Hospitals, General; D006801:Humans; D015735:Mifepristone / Q000627:therapeutic use*; D016595:Misoprostol / Q000627:therapeutic use*; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000187:drug effects; D012189:Retrospective Studies; D014463:Ultrasonography; D006113:United Kingdom
D000020:Abortifacient Agents, Nonsteroidal; D000021:Abortifacient Agents, Steroidal; D016595:Misoprostol; D015735:Mifepristone