Breast cancer with endocrine differentiation: report of two cases showing different histologic patterns.
We report two cases of breast cancer with endocrine differentiation. Case 1 was a 56-year-old woman with a 2-cm tumor in the upper outer quadrant of the right breast and right axillary lymphadenopathy. Excisional biopsy suggested carcinoma and we performed breast-conserving surgery with lymph node dissection. Histologic examination revealed breast cancer with endocrine differentiation resembling small cell carcinoma of the lung, with one nodal metastasis. Case 2 was a 71-year-old woman with a 2.5-cm tumor in the upper outer quadrant of the right breast. Aspiration cytology suggested carcinoma and we performed mastectomy with lymph node dissection. Histologic examination revealed a carcinoid tumor, as one of the breast cancers with endocrine differentiation, but no nodal metastasis. The two patients are now disease-free 26 and 12 months after surgery, respectively.
Ajisaka
Hideyuki
H
Department of Surgery, Toyama Prefectural Central Hospital, Toyama, Japan.
Maeda
Kiichi
K
Miwa
Atsuo
A
Yamamoto
Katsuya
K
D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D002277:Carcinoma / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D004703:Endocrine System / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged