title: Quality of life of living donors before and after living donor liver transplantation.
abstract: Living donor liver transplantation (LDLT) is becoming an established method for treatment of terminal liver disease in adults. After resection of the right hepatic lobe, postoperative complications can arise in healthy donors, and even individual cases of death have been recorded. There remains, however, little research on the psychosocial aspects in living donors before and after LDLT. Using the WHOQOL questionnaire, this prospective study investigates the quality of life (QoL) in a sample of 28 living donors, including the relationship between postoperative complications and QoL before and 6 months after donation. Before LDLT, the donor QoL is high, above that of the general healthy population. After LDLT, a significant reduction in the QoL appears in the areas of "physical health" and "living conditions." Nevertheless, the QoL remains above the level of the general population. Only two donors showed general QoL values below those of the general population. The postoperative complications had no significant influence on the QoL after transplantation. The high QoL of donors following LDLT indicates a positive psychosocial outcome for the majority of donors, irrespective of donation-related complications. Additional psychosocial studies will be necessary to disclose predictors for an unfavorable psychosocial outcome following LDLT.
authors.affiliation: Psychiatric University Clinic, Willhelm Klein-Strasse 27, CH-4025 Basel, Switzerland. marc.walter@pukbasel.ch
authors.forename: M
authors.initials: M
authors.lastname: Walter
authors.forename: G
authors.initials: G
authors.lastname: Dammann
authors.forename: C
authors.initials: C
authors.lastname: Papachristou
authors.forename: A
authors.initials: A
authors.lastname: Pascher
authors.forename: P
authors.initials: P
authors.lastname: Neuhaus
authors.forename: G
authors.initials: G
authors.lastname: Danzer
authors.forename: B F
authors.initials: BF
authors.lastname: Klapp
mesh_terms: D000328:Adult; D005190:Family; D005260:Female; D005858:Germany; D006498:Hepatectomy / Q000523:psychology*; D006801:Humans; D019520:Living Donors / Q000523:psychology*; D008297:Male; D017533:Marital Status; D009679:Nuclear Family; D011788:Quality of Life; D020858:Tissue and Organ Harvesting / Q000523:psychology*