Catalytic asymmetric Nazarov reactions promoted by chiral Lewis acid complexes.
Divinyl ketones bearing alpha-ester or alpha-amide groups undergo Nazarov cyclizations to give cylopentenones using copper-bisoxazoline Lewis acid complexes with moderate to good ees. [reaction: see text]
Aggarwal
Varinder K
VK
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK. v.aggarwal@bristol.ac.uk
Belfield
Andrew J
AJ