Multiple neuronal connexins in the mammalian retina.
Gap junctions are abundant in the mammalian retina and many neuronal types form neural networks. Several different neuronal connexins have now been identified in the mammalian retina. Cx36 supports coupling in the AII amacrine cell network and is essential for processing rod signals. Cx36 is probably also responsible for photoreceptor coupling. Horizontal cells appear to be extensively coupled by either Cx50 or Cx57. These results indicate that multiple neuronal connexins are expressed in the mammalian retina and that different cell types express different connexins.
Massey
Stephen C
SC
Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Houston, TX 77030, USA. Steve.Massey@uth.tmc.edu
O'Brien
Jennifer J
JJ
Trexler
E Brady
EB
Li
Wei
W
Keung
Joyce W
JW
Mills
Stephen L
SL
O'Brien
John
J
D025042:Amacrine Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D001710:Biotin / Q000031:analogs & derivatives* / Q000378:metabolism; D017630:Connexins / Q000378:metabolism*; D005136:Eye Proteins / Q000378:metabolism*; D017629:Gap Junctions / Q000378:metabolism / Q000502:physiology; D012160:Retina / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D017948:Retinal Rod Photoreceptor Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D000097004:Gap Junction delta-2 Protein; D000099264:Connexin 50
D001710:Biotin; D017630:Connexins; D005136:Eye Proteins; D000097004:Gap Junction delta-2 Protein; D000099264:Connexin 50; C070614:neurobiotin