A comparison of the susceptibility of growing mukota and large white pigs to infection with Ascaris suum.
The influence of A. suum infection on the haematology, liver-related serum enzymes, blood urea and live weight gain in Mukota and Large White (LW) weaner pigs was compared. Six pigs of each genotype were infected with a single dose of 4000 A. suum eggs per pig and another six were not. The pigs were kept for 100 days. Blood was collected daily for the first 7 days and also after 100 days. In the infected pigs, there was an increase (p<0.05) in alanine aminotransferase (ALT) activity in the LW but not in the Mukota pigs. Although the alkaline phosphatase (ALP) activity rose (p<0.05) in both infected and non-infected LW pigs from day 1 to day 3, the activity in the non-infected LW pigs then decreased, while that of the infected LW pigs remained elevated. The infected LW pigs had higher (p<0.05) levels of ALT, ALP and aspartate aminotransferase than their non-infected counterparts. Non-infected LW pigs tended to have higher (p<0.05) haematological parameters, daily weight gain and urea concentrations than infected LW pigs, but these differences were not significant. These preliminary findings suggest that more A. suum larvae reached the livers in the LW than in the Mukota pigs and that the latter may be more resistant to A. suum infection.
Zanga
J
J
Department of Paraclinical Veterinary Studies, University of Zimbabwe, PO Box MP 167, Mount Pleasant, Harare, Zimbabwe.
Chimonyo
M
M
Kanengoni
A
A
Dzama
K
K
Mukaratirwa
S
S
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001196:Ascariasis / Q000201:enzymology / Q000469:parasitology / Q000662:veterinary*; D017165:Ascaris suum / Q000254:growth & development*; D001219:Aspartate Aminotransferases / Q000097:blood; D004198:Disease Susceptibility; D004906:Erythrocyte Count / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000201:enzymology / Q000469:parasitology*; D015430:Weight Gain; D015030:Zimbabwe
D006454:Hemoglobins; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase