title: Influence of repeated consumption of beverages containing sucrose or intense sweeteners on food intake.
abstract: OBJECTIVE
  To investigate the influence of ingestion of beverages with sucrose or with intense sweeteners on food intake (FI) and on hunger ratings in before and after a month of daily consumption of beverages.
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  Department of Physiology, University Hospital, Dijon, France.
  
  
  METHODS
  In all, 12 men and 12 women, aged 20-25 y.
  
  
  METHODS
  Four beverages contained either sucrose (E+:100 g/l, 1672 kJ) or intense sweeteners (E-: null energy content) and were flavoured with either orange (O) or raspberry (R). FI was measured in the lab during two 2-consecutive-day periods, carried out on 2 successive weeks (session 1). The subjects drank 2 l of either E+ or E- beverages on the first day of both weekly periods, according to a balanced randomised design. E+ was paired with O for 50% of subjects and with R for the other 50%. Subjects were then habituated over a 4-week period to both beverages, consuming 1 l of E+ beverage on odd days and 1 l of E- drink on even days. After this period, the measurements of session 1 were repeated (session 2, weeks 7-8). Finally, FI was measured for two more 2-day periods (weeks 9-10) after the association between flavour and energy content was reversed (session 3).
  
  
  RESULTS
  The E- drinks were less palatable than the E+ drinks. Besides, we observed that FI was not reduced in response to a liquid extra caloric load and there was no change in hunger ratings after the beverages in any of the sessions.
  
  
  CONCLUSIONS
  Ingestion of caloric beverages induced a positive energy balance and the continuous exposure phase to these beverages over 1 month did not improve FI adaptation in response to the extra energy provided by the beverages.
authors.affiliation: Equipe Nutrition et Métabolisme Humain et CREABIO, Université de Bourgogne, Dijon, France.
authors.forename: V
authors.initials: V
authors.lastname: Van Wymelbeke
authors.forename: M-E
authors.initials: ME
authors.lastname: Béridot-Thérond
authors.forename: V
authors.initials: V
authors.lastname: de La Guéronnière
authors.forename: M
authors.initials: M
authors.lastname: Fantino
mesh_terms: D000328:Adult; D001218:Aspartame / Q000008:administration & dosage / Q000494:pharmacology; D001628:Beverages; D018592:Cross-Over Studies; D019422:Dietary Sucrose / Q000008:administration & dosage* / Q000494:pharmacology; D004435:Eating; D002149:Energy Intake / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006801:Humans; D006815:Hunger / Q000187:drug effects* / Q000502:physiology; D008297:Male; D013549:Sweetening Agents / Q000008:administration & dosage* / Q000494:pharmacology; D013649:Taste
chemical_list: D019422:Dietary Sucrose; D013549:Sweetening Agents; D001218:Aspartame