title: Demethylation of 2,4-dimethoxyquinolines: the synthesis of atanine.
abstract: The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.
authors.affiliation: Department of Chemistry, King's College London, Strand, London, UK WC2R 2LS. keith.jones@kingston.ac.uk
authors.forename: Keith
authors.initials: K
authors.lastname: Jones
authors.forename: Xavier
authors.initials: X
authors.lastname: Roset
authors.forename: Sharon
authors.initials: S
authors.lastname: Rossiter
authors.forename: Philip
authors.initials: P
authors.lastname: Whitfield
mesh_terms: D008745:Methylation; D008956:Models, Chemical; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011804:Quinolines; D015363:Quinolones; C094654:atanine