title: Disseminated lupus vulgaris.
abstract: Lupus vulgaris is the most common form of cutaneous tuberculosis, and usually presents as a solitary lesion on the face. We report two patients with multiple lesions on different skin areas. The first patient presented a diffuse involvement of the right foot, and reddish-brown plaques on the right leg, the back and the face. Spreading of the lesions followed a prolonged application of topical corticosteroids. The second patient showed a large plaque on the nape and occipital area resulting in scarring alopecia, and plaques on the right inguinal and thigh regions. Ziehl-Neelsen staining was negative in both cases, but diagnosis was supported by histology and polymerase chain reaction analysis. No visceral involvement was present. Antituberculosis polychemotherapy was rapidly effective.
authors.affiliation: Istituto Dermopatico dell'Immacolata, IRCCS, Via Monti Di Creta 104, 00167 Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Gisondi
authors.forename: Marie
authors.initials: M
authors.lastname: Perez
authors.forename: Emanuela
authors.initials: E
authors.lastname: Gubinelli
authors.forename: Barbara
authors.initials: B
authors.lastname: Cocuroccia
authors.forename: Marcello
authors.initials: M
authors.lastname: Fazio
authors.forename: Giampiero
authors.initials: G
authors.lastname: Girolomoni
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008177:Lupus Vulgaris / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents