title: Synthesis of 2-(3'-azido- and 3'-amino-3'-deoxy-beta-D-ribofuranosyl)thiazole-4-carboxamide.
abstract: In view of biological activities of tiazofurin and azido or aminosugar nucleosides, novel azido- and amino-substituted tiazofurin derivatives (1 and 2) were efficiently synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose.
authors.affiliation: College of Pharmacy, Seoul National University, Seoul, Korea.
authors.forename: Cheng Wu
authors.initials: CW
authors.lastname: Liang
authors.forename: Myong Jung
authors.initials: MJ
authors.lastname: Kim
authors.forename: Lak Shin
authors.initials: LS
authors.lastname: Jeong
authors.forename: Moon Woo
authors.initials: MW
authors.lastname: Chun
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D009705:Nucleosides / Q000138:chemical synthesis / Q000494:pharmacology; D012254:Ribavirin / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D009705:Nucleosides; D012254:Ribavirin; C033706:tiazofurin