[The investigation on the changes of haematological parameters in the occupationally lead exposed workers].
OBJECTIVE
To estimate the level of blood lead and some haematological parameters in the workers occupationally exposed to lead so as to know the effect of lead exposure on hematopoietic system in exposed workers.


METHODS
The graphite furnace atomic absorption spectrocopy was used to determine blood lead (BPb). The haematological parameters were determined by Sysmex KX-21 automated haematology analyzer.


RESULTS
Hemoglobin (Hb) in the lead-absorption group[male: (129.3 +/- 12.3) g/L, female: (112.2 +/- 9.4) g/L], and hematocrit (HCT) in the lead-absorption group[male: (0.338 +/- 0.030) L/L, female: (0.302 +/- 0.028) L/L] were significantly lower than those in normal people group and lead-exposed group (P < 0.05, P < 0.01). The relationships between BPb and Hb, HCT were weakly negative correlation. Red cell distribution width (RDW) in the lead-absorption group(male: 16.68% +/- 0.80%, female: 16.98% +/- 0.98%) were significantly higher than those in normal people group and lead exposed group, and RDW in lead exposed group (male: 14.77% +/- 0.83%, female: 14.92% +/- 1.13%) were higher than that in normal people group. BPb was weakly positively correlated with RDW.


CONCLUSIONS
Hb, HCT and RDW were three indices which may reflect the occurrences and degrees of anaemia in lead exposed workers.
Peng
Shanzhuo
S
Shenyang No. 9th People's Hospital, Shenyang 110024, China.
Zhang
Chunsheng
C
Wang
Chaohe
C
Wei
Mingzhi
M
Zhang
Jie
J
Xi
Zhuoli
Z
Yang
Xiaoxia
X
D000740:Anemia / Q000139:chemically induced*; D004912:Erythrocytes / Q000187:drug effects; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007854:Lead / Q000097:blood / Q000633:toxicity*; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects*
D006454:Hemoglobins; D007854:Lead