title: In vitro snake venom detoxifying action of some marine algae of Gulf of Mannar, south-east coast of India.
abstract: The extract of the brown seaweed Padina boergesenii and the red seaweed Hypnea valentiae was found to detoxify (in vitro) the venom of Naja nigricollis. There was a remarkable reduction in the mortality of albino mice after intraperitoneal (i.p.) administration of reconstituted venom with the extract compared to those challenged with the venom only. The survival of the animals exposed to the venom incubated with the different concentrations of the extract was used as the in vitro detoxification parameter.
authors.affiliation: Department of Biotechnology, SASTRA, Deemed University, Thanjavur, India.
authors.forename: Hannah R
authors.initials: HR
authors.lastname: Vasanthi
authors.forename: A
authors.initials: A
authors.lastname: Jaswanth
authors.forename: V
authors.initials: V
authors.lastname: Krishnaraj
authors.forename: G V
authors.initials: GV
authors.lastname: Rajamanickam
authors.forename: A
authors.initials: A
authors.lastname: Saraswathy
mesh_terms: D000818:Animals; D000997:Antivenins / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004546:Elapid Venoms / Q000037:antagonists & inhibitors*; D056890:Eukaryota; D007194:India; D007274:Injections, Intraperitoneal; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012624:Seaweed
chemical_list: D000997:Antivenins; D004546:Elapid Venoms; D010936:Plant Extracts