title: Ischemic fasciitis: an unusual vulvovaginal spindle cell lesion.
abstract: Ischemic fasciitis is a benign reactive lesion that most commonly occurs in elderly, immobile patients in weight-bearing areas that are subject to intermittent ischemia with subsequent tissue breakdown and regenerative changes. The lesion can be clinically and pathologically mistaken for malignancy. Here we describe the first reported case of ischemic fasciitis of the vulvovaginal region in a 20-year-old paraplegic woman who presented with a clinically suspicious vulvar swelling. Histologic examination showed surface ulceration and underlying fibrinoid necrosis with surrounding reactive atypical fibroblast-like cells and small blood vessels, the characteristic histologic features of ischemic fasciitis.
authors.affiliation: Department of Pathology, National Maternity Hospital, Dublin, Ireland.
authors.forename: R
authors.initials: R
authors.lastname: Scanlon
authors.forename: P
authors.initials: P
authors.lastname: Kelehan
authors.forename: G
authors.initials: G
authors.lastname: Flannelly
authors.forename: D
authors.initials: D
authors.lastname: McDonald
authors.forename: W G
authors.initials: WG
authors.lastname: McCluggage
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005208:Fasciitis / Q000209:etiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology* / Q000473:pathology*; D010264:Paraplegia / Q000150:complications; D014845:Vulvar Diseases / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology