Assisted reproduction in patients with early-stage ovarian malignancies.
OBJECTIVE
To determine the outcome of women with early-stage ovarian malignancies who subsequently underwent assisted reproductive technologies (ART).


METHODS
Retrospective study.


METHODS
Academic assisted reproductive technology program.


METHODS
Four infertile women who were previously diagnosed with early-stage ovarian malignancies.


METHODS
Controlled ovulation hyperstimulation, IVF, and/or gamete intrafallopian transfer treatments using clomiphene citrate and/or gonadotropins.


METHODS
Development of tumor recurrence and disease-free interval.


RESULTS
All four women remain free of disease for up to 15 years after treatment. Three of the four women achieved pregnancy.


CONCLUSIONS
In patients with early-stage ovarian malignancies, conservative therapy followed by ovarian stimulation for assisted reproduction is an acceptable strategy.
Steinkampf
Michael P
MP
Division of Reproductive Endocrinology and Infertility, University of Alabama at Birmingham, Birmingham, Alabama 35249-7333, USA. msteinkampf@uabmc.edu
Dharia
Sejal P
SP
Hammond
Karen
K
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D010298:Parity; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery*; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted; D016896:Treatment Outcome