title: Radiofrequency ablation in the treatment of pelvic recurrence of rectal cancer.
abstract: The aim was to assess the response to the treatment using thermal radiofrequency ablation in patients with pelvic recurrent rectal cancer. The location of the lesions as well as the placement of the percutaneous probe were guided by computed tomography. All ablations were performed with a RITA Medical Systems Starburst XL (nine-array, 5-cm) thermal ablation catheter and the Model 1500 generator (RITA Medical Systems, Inc.). The radiofrequency ablation treatment was performed in two patients with pelvic recurrent rectal cancer with poor response to chemoradiotherapy with no indication of new surgical treatment and suffering strong pain in the sacrum area. The serum carcinoembryonic antigen had a sharp reduction in a sixty-day period. The post-procedure tomography analysis showed the center of the tumor with necrosis and a ring of edema around it. Both patients had no complaints about the procedure, and they needed to take mild analgesics only on the first day right after the procedure for pain. In the follow-up one patient developed an abscess and needed to be readmitted but without recurrent pelvic pain. An effective response was shown by tumor necrosis and total relief of pain of the sacrum area.
authors.affiliation: Department of Surgical Oncology, Hospital Santa Rita, Santa Casa de Porto Alegre, Fundação Faculdade Federal de Ciências Médicas de Porto Alegre, Brazil. ankalil@maededenscenter.com.br
authors.forename: Antonio Nocchi
authors.initials: AN
authors.lastname: Kalil
authors.forename: Fábio
authors.initials: F
authors.lastname: Santarosa
authors.forename: Lenine
authors.initials: L
authors.lastname: Cunha
authors.forename: Plauto
authors.initials: P
authors.lastname: Beck
authors.forename: Felice
authors.initials: F
authors.lastname: Riccardi
authors.forename: José Vinícius
authors.initials: JV
authors.lastname: Cruz
authors.forename: Jeferson
authors.initials: J
authors.lastname: Vinholes
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D014408:Biomarkers, Tumor / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000097:blood; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D012007:Rectum / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen