Synthesis of nearly monodisperse polystyrene-polypeptide block copolymers via polymerisation of N-carboxyanhydrides.
Primary amine hydrochlorides promote a well-controlled ring-opening polymerisation of Z-L-lysine-N-carboxyanhydride in DMF at 40-80 degrees C; the polystyrene-poly(Z-L-lysine) block copolymers synthesised exhibit a very narrow molecular weight distribution, close to a Poisson distribution.
Dimitrov
Ivaylo
I
Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, Am Mühlenberg 1, 14476 Golm, Germany.
Schlaad
Helmut
H
D000812:Anhydrides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011107:Polylysine / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry*; D013696:Temperature
D000812:Anhydrides; D011108:Polymers; D011137:Polystyrenes; D011107:Polylysine