Pheochromocytoma and functional paraganglioma.
OBJECTIVE
Pheochromocytomas and paragangliomas are rare tumors of chromaffin cell origin. Their identification is likely increasing owing to the increased use of radiographic images detecting incidental adrenal masses.


RESULTS
The pathophysiology of hypertension induced by the release of catecholamines and newly discovered peptides has been shown to be more complex than the concept of episodic catecholamine release.


CONCLUSIONS
This review looks at the most recent advances in the physiology and molecular basis of these tumors.
Roman
Sanziana
S
Yale University School of Medicine, New Haven, CT 06520, USA. Sanziana.roman@yale.edu
D000310:Adrenal Gland Neoplasms / Q000453:epidemiology / Q000503:physiopathology* / Q000532:radiotherapy; D003937:Diagnosis, Differential; D006801:Humans; D006973:Hypertension / Q000209:etiology; D010235:Paraganglioma / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D010673:Pheochromocytoma / Q000453:epidemiology / Q000503:physiopathology* / Q000532:radiotherapy; D019275:Radiopharmaceuticals / Q000627:therapeutic use
D019275:Radiopharmaceuticals