title: Continent urinary diversion and low colorectal anastomosis after pelvic exenteration. Quality of life and complication risk.
abstract: BACKGROUND
  Pelvic exenteration is one of the most destructive gynecologic operations performed on an elective basis, with consequent detrimental effects on the quality of life. The use of reconstructive surgery has significantly improved the quality of life of women undergoing this type of procedure. In this paper we review our experience with continent urinary diversion (Miami Pouch) and low colorectal anastomosis at the Division of Gynecologic Oncology of the University of Miami.
  
  
  METHODS
  Patients who underwent creation of the continent urinary diversion Miami Pouch from 1988 to 1997 and supralevator pelvic exenteration with low colorectal resection and primary anastomosis from 1990 to 1997 have been included in this study. Management of complications, with particular emphasis on the conservative treatment, has been reviewed in detail for each patient. Open surgery and conservative treatment have been compared. Analysis of complications in irradiated and nonirradiated patients was performed.
  
  
  RESULTS
  77 patients who underwent creation of the Miami Pouch entered this study. Forty patients underwent total pelvic exenteration, and 37 patients underwent posterior exenteration. The most common urinary complications were ureteral stricture/obstruction (22.1%), difficult catheterisation (19.5%) and pyelonephritis (16.9%). Conservative management strategies were successfully used in 80% of the complications. Analysis of breakdown and fistula formation after low colorectal anastomosis was performed on 77 patients. Thirty-five percent of the irradiated patients developed anastomotic breakdown or fistulas, while the occurrence of this type of complications was only 7.5% in the nonirradiated group.
  
  
  CONCLUSIONS
  Reconstructive procedures after pelvic exenteration present a significant risk of complications, especially in irradiated patients. Most of the complications related to the creation of continent urinary diversion can safely be treated conservatively. Low colorectal anastomosis carries an acceptable risk of complications in nonirradiated patients, but the risk in irradiated patients is very high, therefore, detailed patient selection and extensive counselling in these groups of patients is mandatory.
authors.affiliation: Department of Obstetrics and Gynecology, Università di Roma Campus Bio-Medico, Via Longoni 69, 00155 Rome, Italy. r.angiolo@unicampus.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Angioli
authors.forename: Pierluigi Benedetti
authors.initials: PB
authors.lastname: Panici
authors.forename: Ramin
authors.initials: R
authors.lastname: Mirhashemi
authors.forename: Luis
authors.initials: L
authors.lastname: Mendez
authors.forename: Guillherme
authors.initials: G
authors.lastname: Cantuaria
authors.forename: Stefano
authors.initials: S
authors.lastname: Basile
authors.forename: Manuel
authors.initials: M
authors.lastname: Penalver
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects* / Q000379:methods; D003107:Colorectal Surgery / Q000009:adverse effects / Q000379:methods; D005260:Female; D006801:Humans; D010385:Pelvic Exenteration; D011183:Postoperative Complications; D011788:Quality of Life; D014547:Urinary Diversion / Q000009:adverse effects* / Q000379:methods