title: Genome of Geobacter sulfurreducens: metal reduction in subsurface environments.
abstract: The complete genome sequence of Geobacter sulfurreducens, a delta-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior. These characteristics, coupled with the possession of many two-component sensors and many c-type cytochromes, reveal an ability to create alternative, redundant, electron transport networks and offer insights into the process of metal ion reduction in subsurface environments. As well as playing roles in the global cycling of metals and carbon, this organism clearly has the potential for use in bioremediation of radioactive metals and in the generation of electricity.
authors.affiliation: Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. bmethe@tigr.org
authors.forename: B A
authors.initials: BA
authors.lastname: Methé
authors.forename: K E
authors.initials: KE
authors.lastname: Nelson
authors.forename: J A
authors.initials: JA
authors.lastname: Eisen
authors.forename: I T
authors.initials: IT
authors.lastname: Paulsen
authors.forename: W
authors.initials: W
authors.lastname: Nelson
authors.forename: J F
authors.initials: JF
authors.lastname: Heidelberg
authors.forename: D
authors.initials: D
authors.lastname: Wu
authors.forename: M
authors.initials: M
authors.lastname: Wu
authors.forename: N
authors.initials: N
authors.lastname: Ward
authors.forename: M J
authors.initials: MJ
authors.lastname: Beanan
authors.forename: R J
authors.initials: RJ
authors.lastname: Dodson
authors.forename: R
authors.initials: R
authors.lastname: Madupu
authors.forename: L M
authors.initials: LM
authors.lastname: Brinkac
authors.forename: S C
authors.initials: SC
authors.lastname: Daugherty
authors.forename: R T
authors.initials: RT
authors.lastname: DeBoy
authors.forename: A S
authors.initials: AS
authors.lastname: Durkin
authors.forename: M
authors.initials: M
authors.lastname: Gwinn
authors.forename: J F
authors.initials: JF
authors.lastname: Kolonay
authors.forename: S A
authors.initials: SA
authors.lastname: Sullivan
authors.forename: D H
authors.initials: DH
authors.lastname: Haft
authors.forename: J
authors.initials: J
authors.lastname: Selengut
authors.forename: T M
authors.initials: TM
authors.lastname: Davidsen
authors.forename: N
authors.initials: N
authors.lastname: Zafar
authors.forename: O
authors.initials: O
authors.lastname: White
authors.forename: B
authors.initials: B
authors.lastname: Tran
authors.forename: C
authors.initials: C
authors.lastname: Romero
authors.forename: H A
authors.initials: HA
authors.lastname: Forberger
authors.forename: J
authors.initials: J
authors.lastname: Weidman
authors.forename: H
authors.initials: H
authors.lastname: Khouri
authors.forename: T V
authors.initials: TV
authors.lastname: Feldblyum
authors.forename: T R
authors.initials: TR
authors.lastname: Utterback
authors.forename: S E
authors.initials: SE
authors.lastname: Van Aken
authors.forename: D R
authors.initials: DR
authors.lastname: Lovley
authors.forename: C M
authors.initials: CM
authors.lastname: Fraser
mesh_terms: D000085:Acetates / Q000378:metabolism; D000105:Acetyl Coenzyme A / Q000378:metabolism; D000332:Aerobiosis; D000693:Anaerobiosis; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D002244:Carbon / Q000378:metabolism; D002633:Chemotaxis; D002876:Chromosomes, Bacterial / Q000235:genetics; D045304:Cytochromes c / Q000235:genetics / Q000378:metabolism; D004579:Electron Transport; D004734:Energy Metabolism; D005798:Genes, Bacterial; D005809:Genes, Regulator; D016680:Genome, Bacterial; D045302:Geobacter / Q000235:genetics* / Q000378:metabolism* / Q000502:physiology; D006859:Hydrogen / Q000378:metabolism; D008670:Metals / Q000378:metabolism*; D009068:Movement; D016366:Open Reading Frames; D010084:Oxidation-Reduction; D010802:Phylogeny
chemical_list: D000085:Acetates; D001426:Bacterial Proteins; D008670:Metals; D000105:Acetyl Coenzyme A; D002244:Carbon; D006859:Hydrogen; D045304:Cytochromes c