Patients with inferior vena caval filters should receive chronic thromboprophylaxis.
A 32-year-old man with testicular carcinoma is diagnosed with an acute left leg deep venous thrombosis (DVT) during his fourth cycle of combination chemotherapy. Because of anticipated moderate to severe thrombocytopenia, anticoagulation is initially avoided and an inferior vena cava (IVC) filter is placed to prevent pulmonary embolism (PE). After completion of all chemotherapy he is deemed to be in remission and anticoagulation is begun. The optimal duration of anticoagulation in this patient is pondered.
Gomes
Marcelo P V
MP
Section of Hematology and Coagulation Medicine, Department of Hematology and Medical Oncology, The Cleveland Clinic Foundation, 9500 Euclid Avenue S60, Cleveland, OH 44195, USA. villaforte@ameritech.net
Kaplan
Karen L
KL
Deitcher
Steven R
SR
D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000150:complications / Q000188:drug therapy; D000075202:Contraindications; D004334:Drug Administration Schedule; D005374:Filtration; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000517:prevention & control*; D013736:Testicular Neoplasms / Q000150:complications / Q000188:drug therapy; D016306:Vena Cava Filters; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000150:complications
D000925:Anticoagulants