title: Immunopotentiating properties of Cryptolepis buchanani root extract.
abstract: The ethanol extract (95%) of the root of the plant Cryptolepis buchanani (EECB) was investigated for immunomodulatory activity in mice and rats. The oral administration of EECB caused significant stimulation of the delayed type hypersensitivity (DTH) reaction and humoral antibody production. The oral LD50 was found to be more than 3 g/kg in both rats and mice.
authors.affiliation: Department of Pharmacology, Regional Research Laboratory, Jammu Tawi, 180 001, India.
authors.forename: Anpurna
authors.initials: A
authors.lastname: Kaul
authors.forename: Sarang
authors.initials: S
authors.lastname: Bani
authors.forename: Usha
authors.initials: U
authors.lastname: Zutshi
authors.forename: K A
authors.initials: KA
authors.lastname: Suri
authors.forename: N K
authors.initials: NK
authors.lastname: Satti
authors.forename: O P
authors.initials: OP
authors.lastname: Suri
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001170:Arthritis, Infectious / Q000517:prevention & control; D031106:Cryptolepis; D004305:Dose-Response Relationship, Drug; D006968:Hypersensitivity, Delayed / Q000517:prevention & control; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D051381:Rats
chemical_list: D000276:Adjuvants, Immunologic; D010936:Plant Extracts