Methemoglobinemia and hemolysis after enteral administration of methylene blue in a preterm infant: relevance for pediatric surgeons.
A preterm infant had methaemoglobulinemia and hemolytic anemia after enteral administration of methylene blue. The dye was administered to exclude a tracheoesophageal fistula. Methylene blue is a noxious product, especially in neonates. It should be considered a potential cause of acquired methemoglobulinemia, even after enteral administration.
Allegaert
K
K
Neonatal Intensive Care Unit, Department of Paediatrics, University Hospitals, Gasthuisberg, Leuven, Belgium.
Miserez
M
M
Lerut
T
T
Naulaers
G
G
Vanhole
C
C
Devlieger
H
H
D004947:Esophagus; D005260:Female; D006461:Hemolysis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000139:chemically induced* / Q000175:diagnosis; D007440:Intubation; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis; D008751:Methylene Blue / Q000008:administration & dosage / Q000009:adverse effects*; D014138:Tracheoesophageal Fistula / Q000175:diagnosis
D008751:Methylene Blue