Lipid peroxidation, vitamins C, E and reduced glutathione levels in patients with pulmonary tuberculosis.
The present study examined the relationship between lipid peroxidation and vitamin C, vitamin E and reduced glutathione levels in plasma, erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients and an equal number of age-and sex-matched healthy subjects. Enhanced plasma, erythrocytes and erythrocyte membrane lipid peroxidation with concomitant decline in vitamin C, vitamin E and reduced glutathione levels were found in pulmonary tuberculosis patients. The elevated lipid peroxidation and decreased vitamin C, vitamin E and reduced glutathione levels indicate the potential of oxidative damage to erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients.
Vijayamalini
M
M
Department of Biochemistry, Faculty of Science, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Manoharan
S
S
D000328:Adult; D001205:Ascorbic Acid / Q000097:blood*; D005978:Glutathione / Q000097:blood*; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis; D014397:Tuberculosis, Pulmonary / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D017392:Thiobarbituric Acid Reactive Substances; D014810:Vitamin E; D005978:Glutathione; D001205:Ascorbic Acid