title: [44-year-old female patient with cutaneous rash, sore throat, fever and arthritis].
abstract: We report on a 44 year old woman with fever, cutaneous rash, severe sore throat, arthritis, leukocytosis, splenomegaly and liver dysfunction. After exclusion of an infectious or malignant disease, adult onset Still's disease was diagnosed according to the Yamaguchi criteria. Reduction of the initial treatment with corticosteroids after 4 month caused a relapse of disease. Thus methotrexate treatment was started, which resulted in improvement of symptoms and inflammatory activity.
authors.affiliation: Abteilung Rheumatologie der Universität Giessen, Herz- und Rheumazentrum Kerckhoff-Klinik Bad Nauheim. johannes.strunk@kerckhoff.med.uni-giessen.de
authors.forename: J
authors.initials: J
authors.lastname: Strunk
authors.forename: K
authors.initials: K
authors.lastname: Strube
authors.forename: U
authors.initials: U
authors.lastname: Lange
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D001168:Arthritis / Q000209:etiology; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007239:Infections / Q000175:diagnosis; D008727:Methotrexate / Q000627:therapeutic use*; D009369:Neoplasms / Q000175:diagnosis; D010612:Pharyngitis / Q000209:etiology; D055502:Secondary Prevention; D016706:Still's Disease, Adult-Onset / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000517:prevention & control; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D008727:Methotrexate