Evaluation of antifungal activity of mineral trioxide aggregate.
The purpose of this investigation was to study, in vitro, the antifungal effect of mineral trioxide aggregate (MTA) using a tube-dilution test. MTA was tested freshly mixed and after 24 h set on Candida albicans. The tested MTA was incubated with C. albicans for 1 h, 24 h, and 3 days. Results showed that the freshly mixed MTA was effective in killing the tested fungi after 1 day of contact, whereas the 24-h set MTA was effective after 3 days of incubation. It was concluded that MTA (freshly mixed and 24-h set) was effective against C. albicans.
Al-Nazhan
Saad
S
Department of Restorative Dental Science, King Saud University, College of Dentistry, Riyadh, Saudi Arabia. snazhan@ksv.edv.sa
Al-Judai
Aziza
A
D017607:Aluminum Compounds / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D017610:Calcium Compounds / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D004338:Drug Combinations; D008826:Microbial Sensitivity Tests; D010087:Oxides / Q000494:pharmacology*; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D017640:Silicates / Q000494:pharmacology*; D018709:Statistics, Nonparametric; D013997:Time Factors
D017607:Aluminum Compounds; D000935:Antifungal Agents; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate