Salivary gland neoplasms.
Treatment and cure of salivary gland neoplasms requires surgical intervention in most cases. For parotid neoplasms, the most common surgical procedure performed is the superficial parotidectomy with facial nerve preservation. Postoperative radiation therapy is indicated in high-grade salivary gland malignancies and malignancies with increased risk of locoregional recurrence. Primary radiation, including neutron beam techniques, may play a role in certain histologic types or nonoperative candidates. Chemotherapy has yet to result in improvements in survival or quality of life in the treatment of salivary gland malignancy. Advances in radiation therapy techniques, including intensity-modulated radiation therapy, provide opportunities for reduced morbidity.
Day
Terry A
TA
Head and Neck Tumor Program, Hollings Cancer Center, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA. dayt@musc.edu
Deveikis
John
J
Gillespie
M Boyd
MB
Joe
John K
JK
Ogretmen
Besim
B
Osguthorpe
J David
JD
Reed
Susan G
SG
Richardson
Mary S
MS
Rossi
Michael
M
Saini
Ranjiv
R
Sharma
Anand K
AK
Stuart
Robert K
RK
D017024:Chemotherapy, Adjuvant / Q000379:methods*; D006801:Humans; D018714:Radiotherapy, Adjuvant / Q000379:methods*; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D013514:Surgical Procedures, Operative / Q000379:methods*