[Diagnosis and follow-up of non-diabetic macular edema with optical coherence tomography (OCT)].
BACKGROUND
Objective and quantitative follow-up of macular edema with present clinical methods is limited. We studied to what extent optical coherence tomography (OCT) may be clinically useful in diagnosis and follow-up of non-diabetic macular edema.


METHODS
We evaluated 106 eyes with non-diabetic macular edema retrospectively considering diagnosis, foveal retinal thickness in OCT, fluorescein angiographic findings and visual acuity.


RESULTS
In 60 of 61 eyes (98%) the diagnosis of macular edema was confirmed by fluorescein angiography. There was only a minor correlation between visual acuity and foveal retinal thickness (r=0.32, p=0.001). Follow-up of 24 eyes showed a statistically significant decrease of foveal retinal thickness under therapy from 420+/-165 microm to 354+/-165 microm (p=0,035) as well as a small improvement in visual acuity from 0.30 to 0.38 (p=0.025).


CONCLUSIONS
OCT can diagnose macular edema non-invasively and thus may replace fluorescein angiography as an invasive method. The reduction of macular edema in the course of therapeutic measures can be documented objectively with OCT.
Schneeberg
A E
AE
Augenklinik, Universität Würzburg.
Göbel
W
W
D003930:Diabetic Retinopathy / Q000175:diagnosis; D003941:Diagnostic Techniques, Ophthalmological; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008269:Macular Edema / Q000175:diagnosis* / Q000601:surgery; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*