The current status of immune modulating therapy for myocarditis: a case of acute parvovirus myocarditis treated with intravenous immunoglobulin.
We present a case of a patient who presented with a febrile illness without obvious source initially, who developed profound cardiac decompensation and left ventricular dysfunction. Viral titers obtained during the course of illness confirmed parvovirus infection. Intravenous aggressive immunoglobulins and medical therapy for heart failure resulted in stabilization and, ultimately, a complete recovery. Recent data from clinical trials are discussed regarding the utility of immunoglobulins in the treatment of myocarditis and heart failure.
Stouffer
George A
GA
Division of Cardiology, The University of Texas Medical Branch at Galveston, Texas, USA.
Sheahan
Richard G
RG
Lenihan
Daniel J
DJ
Patel
Paresh
P
Lenihan
Daniel J
DJ
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007167:Immunotherapy / Q000639:trends; D008875:Middle Aged; D009205:Myocarditis / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D016732:Parvovirus B19, Human / Q000276:immunology
D000276:Adjuvants, Immunologic; D016756:Immunoglobulins, Intravenous