[Ontogenic characteristics of lipid peroxidation and antioxidant system enzymes in the brain of geese].
Peculiarities of antioxidant homeostasis of geese brain tissue during embryogenesis and early postnatal period have been studied. It has been shown that the cerebrum and hindbrain tissues are characterized by a higher level of lipid peroxidation compared to liver. Main antioxidative enzymes' activity (superoxide dismutase, catalase, glutathione peroxidase) in the brain already reaches its maximum in the middle period of embryogenesis. We have found that brain tissues are characterized by a lower activity of intracellular enzymes (superoxide dismutase, catalase) but increased glutathione peroxidase activity as compared to liver. The rate of Fe2+ initialized lipid peroxidation and coefficient of antioxidative activity were used as a criterion for evaluation of antioxidative system's status. According to the dynamics of these factors the highest tension of antioxidative system in the brain appears in the period of the contour (28 days) and juvenile (49 days) feather formation.
Danchenko
O O
OO
Melitopol State Pedagogical University, Ukraine.
Zdorovtseva
L M
LM
Kalytka
V V
VV
D000818:Animals; D001921:Brain / Q000196:embryology / Q000201:enzymology / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D004625:Embryo, Nonmammalian / Q000201:enzymology / Q000378:metabolism; D005777:Geese / Q000196:embryology*; D005979:Glutathione Peroxidase / Q000378:metabolism; D015227:Lipid Peroxidation; D013482:Superoxide Dismutase / Q000378:metabolism; D014815:Vitamins / Q000378:metabolism
D014815:Vitamins; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase