title: Prognosis of migraine with aura.
abstract: The present study is a 16-year follow-up study assessing the long-term outcome of migraine with aura (MA). Additionally possible predictive factors in the prognosis of MA were evaluated. Patients were recruited from the files of Danish headache clinics. A total of 53 patients (11M:42F) with MA (IHS criteria) participated in a follow-up interview. At follow-up attacks had ceased (no MA for 2 years) in 36% of patients. Attacks had ceased in 55% of males and 31% of females (P = 0.17). Attacks had ceased in 41% of patients with visual aura without other aura symptoms and in 25% of those with sensory or aphasic aura besides their visual aura (P = 0.36). Among those with attacks of MA at follow-up frequency of attacks and headache intensity was improved in 44% and 41% of the patients, respectively. The results point to a favourable evolution of MA and suggest possible predictive factors.
authors.affiliation: Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Nordre Ringvej 57, DK-2600 Glostrup, Denmark. kirchmann@dadlnet.dk
authors.forename: M K
authors.initials: MK
authors.lastname: Eriksen
authors.forename: L L
authors.initials: LL
authors.lastname: Thomsen
authors.forename: M B
authors.initials: MB
authors.lastname: Russell
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003718:Denmark / Q000453:epidemiology; D018450:Disease Progression; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D020325:Migraine with Aura / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology*; D011379:Prognosis; D012075:Remission, Spontaneous