Disseminated lupus vulgaris.
Lupus vulgaris is the most common form of cutaneous tuberculosis, and usually presents as a solitary lesion on the face. We report two patients with multiple lesions on different skin areas. The first patient presented a diffuse involvement of the right foot, and reddish-brown plaques on the right leg, the back and the face. Spreading of the lesions followed a prolonged application of topical corticosteroids. The second patient showed a large plaque on the nape and occipital area resulting in scarring alopecia, and plaques on the right inguinal and thigh regions. Ziehl-Neelsen staining was negative in both cases, but diagnosis was supported by histology and polymerase chain reaction analysis. No visceral involvement was present. Antituberculosis polychemotherapy was rapidly effective.
Gisondi
Paolo
P
Istituto Dermopatico dell'Immacolata, IRCCS, Via Monti Di Creta 104, 00167 Rome, Italy.
Perez
Marie
M
Gubinelli
Emanuela
E
Cocuroccia
Barbara
B
Fazio
Marcello
M
Girolomoni
Giampiero
G
D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008177:Lupus Vulgaris / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents