title: Colistin for Klebsiella pneumoniae-associated sepsis.
abstract: Klebsiella pneumoniae that was resistant to all available antibiotics (minimum inhibitory concentration of imipenem, 32 microg/mL), including carbapenems, was isolated from blood samples obtained from a 48-year-old patient in the intensive care unit. The patient developed septic shock, which was successfully treated with colistin, the only antibiotic with activity against this multidrug-resistant strain.
authors.affiliation: Intensive Care Unit, General Hospital of Athens, George Gennimatas, Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Karabinis
authors.forename: E
authors.initials: E
authors.lastname: Paramythiotou
authors.forename: D
authors.initials: D
authors.lastname: Mylona-Petropoulou
authors.forename: A
authors.initials: A
authors.lastname: Kalogeromitros
authors.forename: N
authors.initials: N
authors.lastname: Katsarelis
authors.forename: F
authors.initials: F
authors.lastname: Kontopidou
authors.forename: I
authors.initials: I
authors.lastname: Poularas
authors.forename: H
authors.initials: H
authors.lastname: Malamou-Lada
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003091:Colistin / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple / Q000502:physiology*; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy*; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D018805:Sepsis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D003091:Colistin