[Chlamydia pneumoniae in patients with atherosclerotic ischemia of the lower limbs].
In the group of patients (n = 19), with advanced atheromatous ischemia of the legs the presence and titres of rum IgG, IgA, and IgM antibodies for Chlamydia pneumoniae (Cp) were measured. Those were compared with controls (n = 12). Additionally in the patients undergoing surgery (revascularisation or amputation), specimens of atheromatous arteries were examined for the presence of Cp. In the general population among the people at the age over 60 years the presence of antibodies was common (IgG 100%, IgA 92%). In the patients with the atheromatous ischemia of the legs the antibodies to Cp were found only in: IgG 79%, IgA 79% of them. In 21% of patients (n = 4) we were able to confirm the presence of Cp in an artery wall. However we found that three of them had undetectable titres of serum IgG, IgA, IgM. In case of an individual patient seropositivity to Cp seems not to be a good marker of active chlamydial infection.
Drozdz
Włodzimierz
W
II Katedra Chirurgii Ogólnej Collegium Medicum Uniwersytetu Jagiellońskiego, 31-501 Kraków, ul. Kopernika 21.
Zawilińska
Barbara
B
Wysocki
Andrzej
A
Kleszcz
Ewa
E
Wilczek
Mariusz
M
D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D001161:Arteriosclerosis / Q000150:complications / Q000276:immunology*; D016022:Case-Control Studies; D002690:Chlamydia Infections / Q000150:complications* / Q000276:immunology; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007511:Ischemia / Q000150:complications / Q000209:etiology / Q000276:immunology*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000276:immunology
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M