title: Myeloma management guidelines: a consensus report from the Scientific Advisors of the International Myeloma Foundation.
abstract: These consensus guidelines have been compiled with input from the Scientific Advisors of the International Myeloma Foundation. Their production involved several steps including: A 3-day Scientific Advisors meeting, during which each specific area was presented and discussed (May 2002). Review of key literature, especially randomized study results, but also Medline, Internet, Cochrane database searches, and prior guidelines (Br J Haematol 115: 522-540, 2001). Feedback from patients participating in the International Myeloma Foundation, patient programs. These guidelines encompass both the published literature and expert opinions. Recommendations based upon expert opinions are identified as such. The intent is for the guidelines to be international in scope, plus provide recommendations for both clinical practice and research approaches. 'Consensus' reflects general, although not necessarily unanimous, agreement. Details are discussed as appropriate. For convenience, the recommendations are divided into: 1. Diagnostic criteria. 2. Staging and prognostic factors. 3. Frontline therapy. 4. High-dose therapy and transplant. 5. Maintenance therapy. 6. Supportive care and management of specific complications. 7. Novel therapies and new technologies.
authors.affiliation: Cedars-Sinai Comprehensive Cancer Center, Los Angeles, CA, USA. bdurie@salick.com
authors.forename: Brian G M
authors.initials: BG
authors.lastname: Durie
authors.forename: Robert A
authors.initials: RA
authors.lastname: Kyle
authors.forename: Andrew
authors.initials: A
authors.lastname: Belch
authors.forename: William
authors.initials: W
authors.lastname: Bensinger
authors.forename: Joan
authors.initials: J
authors.lastname: Blade
authors.forename: Mario
authors.initials: M
authors.lastname: Boccadoro
authors.forename: J Anthony
authors.initials: JA
authors.lastname: Child
authors.forename: Raymond
authors.initials: R
authors.lastname: Comenzo
authors.forename: Ben
authors.initials: B
authors.lastname: Djulbegovic
authors.forename: Dorotea
authors.initials: D
authors.lastname: Fantl
authors.forename: Gosta
authors.initials: G
authors.lastname: Gahrton
authors.forename: Jean Luc
authors.initials: JL
authors.lastname: Harousseau
authors.forename: Vania
authors.initials: V
authors.lastname: Hungria
authors.forename: Douglas
authors.initials: D
authors.lastname: Joshua
authors.forename: Heinz
authors.initials: H
authors.lastname: Ludwig
authors.forename: Jayesh
authors.initials: J
authors.lastname: Mehta
authors.forename: Angelina Rodrique
authors.initials: AR
authors.lastname: Morales
authors.forename: Gareth
authors.initials: G
authors.lastname: Morgan
authors.forename: Amara
authors.initials: A
authors.lastname: Nouel
authors.forename: Martin
authors.initials: M
authors.lastname: Oken
authors.forename: Raymond
authors.initials: R
authors.lastname: Powles
authors.forename: David
authors.initials: D
authors.lastname: Roodman
authors.forename: Jesus
authors.initials: J
authors.lastname: San Miguel
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Shimizu
authors.forename: Seema
authors.initials: S
authors.lastname: Singhal
authors.forename: Bhawna
authors.initials: B
authors.lastname: Sirohi
authors.forename: Pieter
authors.initials: P
authors.lastname: Sonneveld
authors.forename: Guido
authors.initials: G
authors.lastname: Tricot
authors.forename: Brian
authors.initials: B
authors.lastname: Van Ness
mesh_terms: D000740:Anemia / Q000209:etiology / Q000628:therapy; D000970:Antineoplastic Agents / Q000592:standards / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000592:standards / Q000627:therapeutic use; D001847:Bone Diseases / Q000209:etiology / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000628:therapy; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D011785:Quality Assurance, Health Care; D033581:Stem Cell Transplantation / Q000592:standards; D016019:Survival Analysis
chemical_list: D000970:Antineoplastic Agents