title: Palliative open heart surgery in an infant with factor VII deficiency.
abstract: An infant with factor VII deficiency underwent palliative open heart surgery for pulmonary atresia with an intact ventricular septum. No references had been found on the management of this rare coagulation disorder in infantile cardiac surgery. We describe the peri- and postoperative management with a replacement therapy including a recombinant factor VIIa concentrate. We conclude that an appropriate replacement therapy is needed to control bleeding during open heart surgery with factor VII deficiency.
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba 305-8575, Japan.
authors.forename: Chiho
authors.initials: C
authors.lastname: Tokunaga
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hiramatsu
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Horigome
authors.forename: Miho
authors.initials: M
authors.lastname: Takahashi-Igari
authors.forename: Mio
authors.initials: M
authors.lastname: Noma
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Sakakibara
mesh_terms: D006348:Cardiac Surgical Procedures; D005167:Factor VII / Q000008:administration & dosage; D005168:Factor VII Deficiency / Q000150:complications / Q000628:therapy; D015942:Factor VIIa; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010166:Palliative Care; D018633:Pulmonary Atresia / Q000150:complications / Q000601:surgery; D011994:Recombinant Proteins / Q000008:administration & dosage
chemical_list: D011994:Recombinant Proteins; D005167:Factor VII; C103587:recombinant FVIIa; D015942:Factor VIIa