[Stress echocardiography with the use of impulse wave tissue Doppler technology in diagnosis and quantitative evaluation of concealed myocardial ischemia].
OBJECTIVE
To elucidate the role of the use of impulse-wave tissue doppler technology during stress echocardiography with transesophageal atrial pacing for diagnosis and evaluation of concealed myocardial ischemia.


METHODS
Patients (n=82, 72 men, 10 women, mean age 43+/-10 years) with syndrome of cardiac pain of obscure etiology.


METHODS
Regional contractility of left ventricular wall was studied through apical approach with the use of 12-segment model. Peak systolic velocity of myocardial segments (S, cm/s), its acceleration (Asl, cm/s(2)), duration of period of preejection (PEP, ms) and isovolumic relaxation time (IVRT, ms) of each segment were calculated at rest, and during subthreshold and threshold pacing.


RESULTS
Concealed myocardial ischemia was revealed by stress echo in 44 patients. Total number of analyzed segments was 984 and parameters of impulse-wave tissue doppler could be measured in 959 (97%) segments. At peak pacing rate during stress test 789 (82%) segments were normokinetic, 142 (15%) - hypokinetic, 20 (2%) - akinetic, and 8 (1%) - dyskinetic. Absence of increase or decrease of S and prolongation of PEP by 10% or more from baseline during stress test were found to be predictors of myocardial ischemia (sensitivity 35 and 75%, respectively, specificity 37 and 81%, respectively), and criteria of objectification of zones of left ventricular wall with impaired contractility (sensitivity 51 and 75%, respectively, specificity 52 and 76%, respectively). During stress echocardiography only dynamics of myocardial IVRT reflected the state of regional left ventricular diastolic function.


CONCLUSIONS
Stress echocardiography with transesophageal atrial pacing combined with impulse-wave tissue doppler imaging is a highly informative method of diagnosis and quantitative assessment of concealed myocardial ischemia.
Vrublevskiĭ
A V
AV
Research Institute for Cardiology of the Research Centre of RAMS Siberian Branch; ul. Kievskaya 111, 634012 Tomsk, Russia.
Boshchenko
A A
AA
Karpov
R S
RS
D000328:Adult; D018619:Echocardiography, Doppler, Pulsed / Q000379:methods*; D025401:Echocardiography, Stress / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology