title: Is fluoride concentration in dentin and enamel a good indicator of dental fluorosis?
abstract: Despite some studies correlating dental fluorosis (DF) and fluoride (F) concentration in dental enamel, no information is available about DF and dentin F concentration. Our objective was to determine the correlation between teeth F concentration and DF severity in unerupted human 3rd molars, and the correlation between dentin and enamel F concentrations in the same tooth. Ninety-nine 3rd molars were studied-53 from Fortaleza, Brazil (F water, 0.7 ppm), 22 from Toronto (1.0 ppm), and 24 from Montreal (0.2 ppm). DF severity was evaluated according to the Thylstrup-Fejerskov Index, while F concentration was analyzed by Instrumental Neutron Activation Analysis. DF severity varied between TF0 and TF4, while F concentration ranged between 39 and 550 ppm in enamel and 101 and 860 ppm in dentin. Our results showed correlation between dentin F concentration and DF (r(S) = 0.316, p = 0.001), but no correlation between enamel F concentration and DF (r(S) = 0.154, p = 0.133). No correlation was observed between dentin and enamel F concentrations in the same tooth (r(S) = 0.064, p = 0.536).
authors.affiliation: Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1X5, Canada.
authors.forename: A P G F
authors.initials: AP
authors.lastname: Vieira
authors.forename: R
authors.initials: R
authors.lastname: Hancock
authors.forename: H
authors.initials: H
authors.lastname: Limeback
authors.forename: R
authors.initials: R
authors.lastname: Maia
authors.forename: M D
authors.initials: MD
authors.lastname: Grynpas
mesh_terms: D000328:Adult; D002327:Cariostatic Agents / Q000032:analysis*; D003743:Dental Enamel / Q000737:chemistry*; D003804:Dentin / Q000737:chemistry*; D005459:Fluorides / Q000032:analysis*; D009050:Fluorosis, Dental / Q000145:classification / Q000175:diagnosis*; D006801:Humans; D008964:Molar, Third / Q000737:chemistry; D009501:Neutron Activation Analysis; D018709:Statistics, Nonparametric; D014097:Tooth, Unerupted / Q000378:metabolism; D014881:Water Supply / Q000032:analysis
chemical_list: D002327:Cariostatic Agents; D005459:Fluorides