title: [Treatment of laryngeal granuloma with anti-extraesophageal reflux medication].
abstract: OBJECTIVE
  To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas.
  
  
  METHODS
  Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily).
  
  
  RESULTS
  All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment.
  
  
  CONCLUSIONS
  Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis.
authors.affiliation: Servicio de Otorrinolaringología, Hospitales Universitarios Virgen del Rocío, Sevilla. benaixa@eresmas.com
authors.forename: J P
authors.initials: JP
authors.lastname: Benaixa
authors.forename: F
authors.initials: F
authors.lastname: Esteban
authors.forename: J M
authors.initials: JM
authors.lastname: González-Pérez
authors.forename: R
authors.initials: R
authors.lastname: Martínez-Garrido
mesh_terms: D000368:Aged; D000536:Aluminum Hydroxide; D000863:Antacids; D000897:Anti-Ulcer Agents; D002254:Carbonates; D020117:Cisapride; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy; D015769:Granuloma, Respiratory Tract / Q000188:drug therapy*; D006801:Humans; D007818:Laryngeal Diseases / Q000188:drug therapy*; D008276:Magnesium Hydroxide; D008297:Male; D008875:Middle Aged; D009853:Omeprazole; D011446:Prospective Studies
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents; D002254:Carbonates; C043698:almagate; D000536:Aluminum Hydroxide; D009853:Omeprazole; D008276:Magnesium Hydroxide; D020117:Cisapride