Génolevures: comparative genomics and molecular evolution of hemiascomycetous yeasts.
The Génolevures online database (http://cbi.labri.fr/Genolevures/) provides data and tools to facilitate comparative genomic studies on hemiascomycetous yeasts. Now, four complete genome sequences recently determined (Candida glabrata, Kluyveromyces lactis, Debaryomyces hansenii, Yarrowia lipolytica) have been added to the partial sequences of 13 species previously analysed by a random approach. The database also includes the reference genome Saccharomyces cerevisiae. Data are presented with a focus on relations between genes and genomes: conservation of genes and gene families, speciation, chromosomal reorganization and synteny. The Génolevures site includes a community area for specific studies by members of the international community.
Sherman
David
D
LaBRI, Laboratoire Bordelais de Recherche en Informatique, UMR CNRS 5800, 351 cours de la Libération, 33405 Talence cedex, France. sherman@labri.fr
Durrens
Pascal
P
Beyne
Emmanuelle
E
Nikolski
Macha
M
Souciet
Jean-Luc
JL
D019295:Computational Biology; D030541:Databases, Genetic; D019143:Evolution, Molecular; D016681:Genome, Fungal; D023281:Genomics; D016247:Information Storage and Retrieval; D020407:Internet; D012984:Software; D015003:Yeasts / Q000235:genetics*