title: Polycyclic aromatic hydrocarbons in foods: human exposure through the diet in Catalonia, Spain.
abstract: The dietary intake of 16 polycyclic aromatic hydrocarbons (PAHs) (naphthalene, acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]anthracene, benzo[g,h,i]perylene, and indeno[1,2,3-c,d]pyrene) by the general population of Catalonia, Spain, was calculated. Concentrations of PAHs in food samples randomly acquired in seven cities of Catalonia from June to August 2000 were measured. Eleven food groups were included in the study. High-performance liquid chromatography was used to analyze PAHs. The dietary intakes of total and carcinogenic PAHs was calculated for five population groups: children, adolescents, male adults, female adults, and seniors. Among the analyzed PAHs, there was a predominance of phenanthrene (16.7 microg/kg) and pyrene (10.7 microg/kg). By food group, the highest levels of total PAHs were detected in cereals (14.5 microg/kg) and in meat and meat products (13.4 microg/kg). The mean estimated dietary intake of the sum of the 16 PAHs was as follows: male adults, 8.4 microg/day; adolescents, 8.2 microg/day; children, 7.4 microg/day; seniors, 6.3 microg/day; female adults, 6.3 microg/day. The calculated daily intake of PAHs would be associated with a 5/106 increase in the risk for the development of cancer in a male adult with a body weight of 70 kg.
authors.affiliation: Toxicology Unit, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.
authors.forename: Gemma
authors.initials: G
authors.lastname: Falcó
authors.forename: Jose L
authors.initials: JL
authors.lastname: Domingo
authors.forename: Juan M
authors.initials: JM
authors.lastname: Llobet
authors.forename: Angel
authors.initials: A
authors.lastname: Teixidó
authors.forename: Conrad
authors.initials: C
authors.lastname: Casas
authors.forename: Lutz
authors.initials: L
authors.lastname: Müller
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002273:Carcinogens / Q000008:administration & dosage / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004032:Diet; D002523:Edible Grain / Q000737:chemistry; D005260:Female; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D008297:Male; D008460:Meat / Q000032:analysis; D008875:Middle Aged; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D012307:Risk Factors; D013030:Spain
chemical_list: D002273:Carcinogens; D011084:Polycyclic Aromatic Hydrocarbons