title: Colo-rectal anastomotic leakage often masquerades as a cardiac complication.
abstract: OBJECTIVE
  The aim of this study was to identify the mode of presentation of patients with clinical anastomotic leaks following restorative colorectal resection for carcinoma.
  
  
  METHODS
  Prospective information was collected on all patients having restorative resection of colorectal cancer. These data were reviewed for a five-year period (1994-1998) to identify all patients who had suffered a clinical anastomotic leak and their notes were retrieved and reviewed.
  
  
  RESULTS
  Three hundred and seventy-nine patients underwent restorative resection for colorectal cancer during the study period (178 female, 201 male), mean age 70 years (range 36-94). There were 22 (6%) clinical anastomotic leaks. Seven (32%) patients presented with obvious abdominal peritonitis. The remaining 15 (68%) were initially misdiagnosed. Thirteen (59%) patients were treated for cardiac symptoms, 1 (5%) patient for obstruction and 1 (5%) for ascites. The delay in diagnosis ranged from 0 to 11 days (mean 4 days). For the whole series of 379 there were 30 patients who suffered cardiac symptoms (8%) 13(43%) of whom had an anastomotic leak.
  
  
  CONCLUSIONS
  Patients who develop cardiac symptoms following restorative colorectal resection for carcinoma should have a water soluble enema as there is a 40% chance that they will have an anastomotic leak.
authors.affiliation: Department of Surgery, Leicester General Hospital, Leicester, UK. crisdsutton@msn.com
authors.forename: C D
authors.initials: CD
authors.lastname: Sutton
authors.forename: L J
authors.initials: LJ
authors.lastname: Marshall
authors.forename: N
authors.initials: N
authors.lastname: Williams
authors.forename: D P
authors.initials: DP
authors.lastname: Berry
authors.forename: W M
authors.initials: WM
authors.lastname: Thomas
authors.forename: M J
authors.initials: MJ
authors.lastname: Kelly
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000009:adverse effects; D003106:Colon / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000601:surgery*; D003951:Diagnostic Errors; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis*; D011446:Prospective Studies; D012007:Rectum / Q000601:surgery*