title: Spleen metastasis from thyroid carcinoma. Report of a case with diagnosis by fine needle aspiration cytology.
abstract: BACKGROUND
  Lymphoreticular malignancies are the most common neoplasms involving the spleen. Metastasis can be caused by direct invasion from surrounding tumors or from hematogenous spread. Spleen metastases from thyroid carcinoma are unusual, and only 1 case has been reported; none have been diagnosed by fine needle aspiration cytology (FNAC).
  
  
  METHODS
  A 75-year-old female was diagnosed 6 months earlier with a poorly differentiated thyroid carcinoma with wide lymphatic and vascular invasion. Abdominal computed tomography (CT) and magnetic resonance imaging showed several spleen nodules. FNAC was performed under CT guidance. Cytologic examination showed atypical epithelial cells with thyroidal characteristics.
  
  
  CONCLUSIONS
  This case had the cytologic findings of a poorly differentiated carcinoma of the thyroid metastatic to spleen. We confirmed the rarity of this pathology and the efficacy of splenic FNAC in the diagnosis.
authors.affiliation: Service of Pathology, Hospital Universitario de Tarragona Juan XXIII, C/Dr. Mallafré Guasch, 4, 43007 Tarragona, Spain. ema@fmcs.urv.es
authors.forename: Emilio
authors.initials: E
authors.lastname: Mayayo
authors.forename: Susana
authors.initials: S
authors.lastname: Blázquez
authors.forename: Virginia
authors.initials: V
authors.lastname: Gómez-Aracil
authors.forename: Amadeo
authors.initials: A
authors.lastname: Saurí
authors.forename: Salomé
authors.initials: S
authors.lastname: Martinez
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D013964:Thyroid Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed