title: Cases from the aerospace medicine residents' teaching file. Transient ischemic attack in an aviator with patent foramen ovale and Factor V Leiden.
abstract: A case report is presented of a naval aviator who suffered a transient ischemic attack (TIA) 1 mo after experiencing right leg pain and swelling following a 4-d drive. Although a venous thrombotic source was never discovered, the presence of both a patent foramen ovale and a thrombophilic condition supports paradoxical embolism (PDE) as the cause of this pilot's TIA. The presentation, diagnosis, treatment, and aeromedical disposition of TIA secondary to a PDE is discussed.
authors.affiliation: Naval Aerospace Medical Institute, Pensacola, FL, USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Radimer
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000401:Aircraft; D003937:Diagnosis, Differential; D005165:Factor V; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006801:Humans; D002546:Ischemic Attack, Transient / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D008297:Male; D008487:Medical History Taking; D012307:Risk Factors; D020246:Venous Thrombosis / Q000150:complications*
chemical_list: C095381:factor V Leiden; D005165:Factor V