title: Ovarian choriocarcinoma arising from partial mole as evidenced by deoxyribonucleic acid microsatellite analysis.
abstract: BACKGROUND
  Recent developments in genetic analysis allow determination of the origin of choriocarcinoma (ie, gestational or nongestational), which helps determine the strategy for clinical treatment of the disease.
  
  
  METHODS
  We present a case of ovarian choriocarcinoma forming a huge ovarian mass 40 days after the patient's last menstrual period. Deoxyribonucleic acid microsatellite analysis of the tumor revealed that it contained a single maternal and two paternal alleles at several independent loci, consistent with the tumor resulting from ovarian pregnancy of a partial hydatidiform mole.
  
  
  CONCLUSIONS
  This is the first description of an ovarian pregnancy of a partial hydatidiform mole-derived ovarian choriocarcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Namba
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Nakagawa
authors.forename: Naohito
authors.initials: N
authors.lastname: Nakamura
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takazawa
authors.forename: Koji
authors.initials: K
authors.lastname: Kugu
authors.forename: Osamu
authors.initials: O
authors.lastname: Tsutsumi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Taketani
mesh_terms: D000328:Adult; D000483:Alleles; D002822:Choriocarcinoma / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D018895:Microsatellite Repeats; D010051:Ovarian Neoplasms / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D010298:Parity; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery