title: Manipulating parallel circuits: the perioperative management of patients with complex congenital cardiac disease.
abstract: In all patients undergoing cardiac surgery, the effective delivery of oxygen to the tissues is of paramount importance. In the patient with relatively normal cardiac structures, the pulmonary and systemic circulations are relatively independent of each other. In the patient with a functional single ventricle, the pulmonary and systemic circulations are dependent on the same pump. As a consequence of this interdependency, the haemodynamic changes following complex palliative procedures, such as the Norwood operation, can be difficult to understand. Comparison of the newly created surgical connections to a simple set of direct current electrical circuits may help the practitioner to successfully care for the patient. In patients undergoing complex palliations, the pulmonary and systemic circulations can be compared to two circuits in parallel. Manipulations of variables, such as resistance or flow, in one circuit, can profoundly affect the performance of the other circuit. A large pulmonary flow might result in a large increase in the saturation of haemoglobin with oxygen returning to the heart via the pulmonary veins at the expense of a decreased systemic flow. Accurate balancing of these parallel circulations requires an appreciation of all interventions that can affect individual components of both circulations.
authors.affiliation: Department of Paediatric Cardiology, Gasthuisberg University Hospital, Catholic University of Leuven, Belgium. lawrenso@ich.uct.ac.za
authors.forename: John
authors.initials: J
authors.lastname: Lawrenson
authors.forename: Benedicte
authors.initials: B
authors.lastname: Eyskens
authors.forename: Dirk
authors.initials: D
authors.lastname: Vlasselaers
authors.forename: Marc
authors.initials: M
authors.lastname: Gewillig
mesh_terms: D006348:Cardiac Surgical Procedures; D006330:Heart Defects, Congenital / Q000503:physiopathology* / Q000601:surgery; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000503:physiopathology / Q000601:surgery; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood; D010166:Palliative Care; D019990:Perioperative Care; D011652:Pulmonary Circulation; D014655:Vascular Resistance
chemical_list: D010100:Oxygen