title: Review of the quality monitoring methods used by countries using or implementing universal leukoreduction.
abstract: Several countries are implementing or have implemented universal leukoreduction (ULR). Specifications, leukocyte counting, and monitoring methods were essential elements in achieving process confidence and conformance. A review of these protocols is presented. A questionnaire was prepared, agreed, and circulated, and responses were collated. Different specifications have been adopted as well as disparate approaches to leukocyte counting and residual leukocyte monitoring. Parametric, nonparametric, and pass-rate methods of analysis were used. Despite these differences, users were satisfied that the methodologies were providing assurance of component quality.
authors.affiliation: Birmingham Blood Center, National Blood Service, Birmingham, United Kingdom. neil.beckman@nbs.nhs.uk
authors.forename: Neil
authors.initials: N
authors.lastname: Beckman
authors.forename: Graham
authors.initials: G
authors.lastname: Sher
authors.forename: Maurice
authors.initials: M
authors.lastname: Masse
authors.forename: Ekkehard
authors.initials: E
authors.lastname: Richter
authors.forename: Juergen
authors.initials: J
authors.lastname: Ringwald
authors.forename: Paolo
authors.initials: P
authors.lastname: Rebulla
authors.forename: Pieter
authors.initials: P
authors.lastname: van der Meer
authors.forename: Benvindo
authors.initials: B
authors.lastname: Justica
authors.forename: Brian
authors.initials: B
authors.lastname: Walker
authors.forename: Graham
authors.initials: G
authors.lastname: Rowe
mesh_terms: D002469:Cell Separation / Q000379:methods*; D005374:Filtration; D005434:Flow Cytometry; D006801:Humans; D007391:International Cooperation; D007958:Leukocyte Count; D011786:Quality Control; D013223:Statistics as Topic; D011795:Surveys and Questionnaires