[Lymph node mapping and sentinel node detection in carcinoma of the cervix, endometrium and vulva].
OBJECTIVE
Validity of the sentinel node concept in patients with cervical, endometrial and vulvar cancer.


METHODS
47 cases of FIGO stage I and II cervical cancer, 33 cases of first clinical stage of endometrial cancer and 37 patients with FIGO stage I and II of vulvar cancer. In cervical and vulvar cancer preoperative lymphoscyntygraphy and intraoperative lymphatic mapping with blue dye and handheld gamma probe were performed. In patients with endometrial cancer intraoperative lymphatic mapping with blue dye injected into the cervix and into the uterine corpus subserously were done. In the last 10 cases radiolabeled nannocolloid were administered and the patients underwent preoperative lymphoscyntygraphy and intraoperative radio detection of sentinel node. Sentinel nodes were labeled as blue, radioactive, or blue/radioactive.


RESULTS
In cervical cancer sensitivity of the dye and radiocolloid methods was 94%, specificity 100% and negative predictive value 97%. Out of 33 cases of endometrial cancer sentinel node was identified in 29 (87.87%) patients. None of women with histological negative sentinel node had metastases in the rest of lymph nodes resected. Sentinel node was detected in all cases of vulvar cancer. The status of sentinel nodes were representative for all lymph node resected.


CONCLUSIONS
Concept of sentinel node may be applied first of all for vulvar cancer and also for cervical and endometrial cancer.
Pityński
Kazimierz
K
Katedry Ginekologii i Połoznictwa Collegium Medicum UJw Krakowie.
Basta
Antoni
A
Opławski
Marcin
M
Przeszlakowski
Dominik
D
Hubalewska-Hoła
Alicja
A
Krysztopowicz
Wiesław
W
D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D017556:Technetium Compounds; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*
D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D017556:Technetium Compounds