title: Juxta-articular myxoma: a rare cause of painful restricted motion of the knee.
abstract: A 68-year-old athletic woman presented to our institution in January 2002 with a several-month history of progressing complaints of pain, swelling, and loss of motion in the right knee. These manifestations had begun the previous July during a game of tennis. She experienced persisting pain and recurring effusions. Because the patient had been residing in another state between July and January, rheumatologic and orthopaedic evaluations of the knee, including a magnetic resonance imaging (MRI), had been performed at a geographically distant (but affiliated) institution. The resulting presumptive diagnosis was a "wear and tear" degenerative articular disorder of the knee. A program of anti-inflammatory medication and physical therapy was begun for several months but produced no therapeutic benefit by the time the patient presented at our institution. After examination confirmed marked losses of both flexion and extension of the knee, effusion, and exquisite medial joint tenderness, an MRI was repeated, using intra-articular gadolinium as a contrast agent. It revealed an intra-articular mass encircling the medial and posterior extents of the medial femoral condyle. An arthroscopic multiportal excisional biopsy was performed. It revealed the existence of a juxta-articular myxoma. The patient recovered most of the range of motion during the next several months, and the effusion and severe pain gradually dissipated. The patient was subsequently followed by sequential physical examinations and MRIs, performed at increasing intervals of time, without recurrence of a mass or of her flagrant symptoms in the first year post surgery. Though the patient's diagnosis was established and treatment outcome was satisfactory, many issues were brought up in this case regarding most appropriate selection of diagnostic tests and treatment approaches.
authors.affiliation: jminkmd@yahoo.com
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Minkoff
authors.forename: Steven
authors.initials: S
authors.lastname: Stecker
authors.forename: Jose
authors.initials: J
authors.lastname: Irizarry
authors.forename: Mitchell
authors.initials: M
authors.lastname: Whiteman
authors.forename: Sherry
authors.initials: S
authors.lastname: Woodhouse
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000473:pathology; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000175:diagnosis*; D009232:Myxoma / Q000175:diagnosis*; D016059:Range of Motion, Articular