title: Antifungal activity of wogonin.
abstract: The antifungal activity of the wogonin isolated from Holmskioldia sanguinea Retz was determined on four different fungal organisms. The pure compound wogonin significantly inhibited the growth of Aspergillus niger, Penicillium frequentance, P. notatum and Botrytis cinerea, in a concentration dependent fashion, when tested by turbidity and spore germination methods. The effects produced by the compound were compared with the standard antifungal agent griseofulvin.
authors.affiliation: Department of Phytochemistry, National Botanical Research Institute, Lucknow 226001, India. drmpal@rediffmail.com
authors.forename: Mahesh
authors.initials: M
authors.lastname: Pal
authors.forename: Harsha
authors.initials: H
authors.lastname: Joshi
authors.forename: V P
authors.initials: VP
authors.lastname: Kapoor
authors.forename: P
authors.initials: P
authors.lastname: Pushpangadan
authors.forename: Leena
authors.initials: L
authors.lastname: Chaurasia
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D044950:Flavanones / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D018515:Plant Leaves; D029648:Verbenaceae
chemical_list: D000935:Antifungal Agents; D044950:Flavanones; D010936:Plant Extracts; D006118:Griseofulvin; C085514:wogonin