Clinical phenotype of haemoglobin Q-H disease.
Seven patients of Chinese origin who had haemoglobin (Hb) Q-H disease were studied. They were found to have a similar clinical phenotype to that of patients with deletional Hb H disease, who have a near identical genotypic configuration. The complete absence of Hb A in Hb Q-H disease and the similar clinical phenotype to deletional Hb H disease lends support to the observation that Hb Q-Thailand shares similar functional properties with Hb A.
Leung
K F S
KF
Ma
E S K
ES
Chan
A Y Y
AY
Chan
L C
LC
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006441:Hemoglobin A / Q000032:analysis; D006447:Hemoglobin H / Q000032:analysis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D013789:Thalassemia / Q000097:blood*
D006455:Hemoglobins, Abnormal; C049214:hemoglobin Q Thailand; D006441:Hemoglobin A; D006447:Hemoglobin H