Weighing the role of hypothalamic feeding neurotransmitters.
Growing health problems related to obesity have focused considerable attention on a number of neurotransmitters, particularly hypothalamic neuropeptides, involved in regulating energy homeostasis and food intake. As the fast-acting transmitters GABA and glutamate underlie the majority of fast synaptic activity in the hypothalamus, understanding neuropeptide modulation of amino acid transmitter actions may be key to a full appreciation of how the brain controls caloric balances.
van den Pol
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Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. anthony.vandenpol@yale.edu
D000818:Animals; D005247:Feeding Behavior / Q000502:physiology*; D018698:Glutamic Acid / Q000502:physiology*; D006801:Humans; D007031:Hypothalamus / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology; D009765:Obesity / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D018377:Neurotransmitter Agents; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid