An efficient recognition motif for an alkyl moiety in water.
The artificial receptor bearing decamethylene groups bridging the porphyrin framework and the hydrophilic poly(ethylene oxide) auxiliary groups showed incremental binding free energy of 3.5 kJ mol(-1) per CH2 for 4-alkylpyridines, demonstrating that an ideal hydrophobic environment for the recognition of an alkyl group is constructed in water.
Mizutani
Tadashi
T
Department of Molecular Science and Technology, Faculty of Engineering, Doshisha University, Kyotanabe, Kyoto 610-0321, Japan. tmizutan@mail.doshisha.ac.jp
Kozake
Katsuyuki
K
Wada
Kenji
K
Kitagawa
Susumu
S