title: Involvement of the medial amygdaloid nucleus in restraint stress-induced pressor responses in rats.
abstract: Restraint stress increased the number of neurons with Fos immunoreactivity in the medial amygdaloid nucleus in rats and caused an increase in blood pressure. The stress-induced pressor response was inhibited by muscimol (80 pmol), a neuroinhibitory compound, injected bilaterally into the medial amygdaloid area, whereas muscimol (8 pmol) similarly injected had only a tendency of inhibition of the pressor response. These data suggest that the medial amygdaloid nucleus is involved in mediation of the restraint stress-induced pressor response.
authors.affiliation: Department of Pharmacology, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan. kubo@ac.shoyaku.ac.jp
authors.forename: Takao
authors.initials: T
authors.lastname: Kubo
authors.forename: Hideaki
authors.initials: H
authors.lastname: Okatani
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nishigori
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Hagiwara
authors.forename: Ryuji
authors.initials: R
authors.lastname: Fukumori
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Goshima
mesh_terms: D000679:Amygdala / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D018755:GABA Agonists / Q000494:pharmacology; D008297:Male; D009118:Muscimol / Q000494:pharmacology; D009474:Neurons / Q000378:metabolism; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D051381:Rats; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000503:physiopathology*
chemical_list: D018755:GABA Agonists; D016760:Proto-Oncogene Proteins c-fos; D009118:Muscimol