title: Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma.
abstract: Although most cases of stiff-limb syndrome are unassociated with malignancy, occasional cases have been associated with breast and lung cancer. Only four reported patients have had cancer and stiff-limb syndrome associated with anti-GAD antibodies. We report the first case of stiff-limb syndrome in a patient with multiple myeloma undergoing treatment with thalidomide, and explore the potential link to the cancer and its treatment.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh Medical Center, USA. ds4jd@virginia.edu
authors.forename: David
authors.initials: D
authors.lastname: Schiff
authors.forename: Josep
authors.initials: J
authors.lastname: Dalmau
authors.forename: Delynne J
authors.initials: DJ
authors.lastname: Myers
mesh_terms: D005260:Female; D005968:Glutamate Decarboxylase / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy; D016750:Stiff-Person Syndrome / Q000209:etiology* / Q000276:immunology; D013792:Thalidomide / Q000627:therapeutic use
chemical_list: D007074:Immunoglobulin G; D013792:Thalidomide; D005968:Glutamate Decarboxylase