title: Efficacy of real-time monitoring to determine motility in porcine small intestinal transplantation.
abstract: Orthotropic small intestinal transplantation (SIT) was performed in outbred 20 pigs. The interdigestive motor patterns were evaluated using strain gage (SG) force transducers. Seven pigs without SIT were treated as control (C) group. Based on the obtained data, the group, which could be detected the migrating motor complex (MMC) in the graft and alive with adequate oral feeding, was regarded as functional graft (FG) group, whereas the group which had available data recorded within 10 days before the death due to rejection was regarded as rejection (R) group. The MMC was analyzed using following parameters: duration; amplitude; and interval. In group FG, all parameters were almost same as group C, thus suggesting that the allograft in group FG had a normal motor function. In contrast, all parameters in group R were significantly lower than those in group FG, suggesting that the motility in group R was impaired. The SG method could monitor the real-time motility and was efficient for detecting the rejection of SIT.
authors.affiliation: Department of Pediatric Surgery, Reproductive and Developmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, 812-8582, Higashi-ku, Fukuoka, Japan. nisimoto@pedsurg.med.kyushu-u.ac.jp
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nishimoto
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Taguchi
authors.forename: Kouji
authors.initials: K
authors.lastname: Masumoto
authors.forename: Keiko
authors.initials: K
authors.lastname: Ogita
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Nakamura
authors.forename: Shohei
authors.initials: S
authors.lastname: Taguchi
authors.forename: Narito
authors.initials: N
authors.lastname: Takada
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Suita
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D004435:Eating / Q000502:physiology; D005769:Gastrointestinal Motility / Q000502:physiology*; D006084:Graft Rejection / Q000503:physiopathology; D006085:Graft Survival / Q000502:physiology; D007082:Ileum / Q000503:physiopathology / Q000637:transplantation*; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D016065:Myoelectric Complex, Migrating / Q000502:physiology; D013552:Swine; D013997:Time Factors; D014159:Transducers