Antiparasitic activities of medicinal plants used in Ivory Coast.
During an ethnopharmacological survey of antiparasitic medicinal plants used in Ivory Coast, 17 plants were identified and collected. Polar, non-polar and alkaloidic extracts of various parts of these species were evaluated in vitro in an antiparasitic drug screening. Antimalarial, leishmanicidal, trypanocidal, antihelminthiasis and antiscabies activities were determined. Among the selected plants, Anogeissus leiocarpus and Terminalia glaucescens were strongly active against Plasmodium falciparum. Lawsonia inermis, selectively prescribed against trypanosomiasis shows interesting trypanocidal activities as did other 15 plants. Anthelmintic activities were found for 10 active species and 2 species (Uvaria afzelli and Monodora myristica) were actives against mites.
Okpekon
T
T
Laboratoire de Chimie, UFR des Sciences Pharmaceutiques et Biologiques, 22 BP 714, République de Côte d'Ivoire, Abidjan, France.
Yolou
S
S
Gleye
C
C
Roblot
F
F
Loiseau
P
P
Bories
C
C
Grellier
P
P
Frappier
F
F
Laurens
A
A
Hocquemiller
R
R
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology; D000962:Antimalarials / Q000494:pharmacology; D000977:Antiparasitic Agents / Q000494:pharmacology*; D007560:Cote d'Ivoire; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D014344:Trypanocidal Agents / Q000494:pharmacology
D000871:Anthelmintics; D000962:Antimalarials; D000977:Antiparasitic Agents; D010936:Plant Extracts; D014344:Trypanocidal Agents