title: Characterization of the tissue-specific expression of the s100P gene which encodes an EF-hand Ca2+-binding protein.
abstract: S100 proteins are a calcium-binding protein family containing two EF-hand domains exclusively expressed in vertebrates and play roles in many cellular activities. Human S100P gene was first cloned as a 439 bp cDNA in placenta and it was found to be associated with human prostate cancer. Here we describe the cloning of the 1297 bp full-length cDNA, and the characterization of the tissue-specific expression of the human S100P gene. It is abundantly expressed in many tissues including placenta by Northern blot and RT-PCR analysis, unlike the expression pattern of other S100 family genes.
authors.affiliation: Department of General Surgery, Changhai Hospital, Shanghai 200433, People's Republic of China.
authors.forename: Gang
authors.initials: G
authors.lastname: Jin
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.forename: Xiangui
authors.initials: X
authors.lastname: Hu
authors.forename: Zaiping
authors.initials: Z
authors.lastname: Jing
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Chen
authors.forename: Kang
authors.initials: K
authors.lastname: Ying
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
authors.forename: Yumin
authors.initials: Y
authors.lastname: Mao
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003001:Cloning, Molecular; D020832:EF Hand Motifs; D015723:Gene Library; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D014018:Tissue Distribution
chemical_list: D002118:Calcium