title: [Recent changes of organism and treatment in pyogenic liver abscess].
abstract: OBJECTIVE
  With the advance of antibiotics and the development of newer imaging techniques, marked changes in etiology, diagnosis, treatment and prognosis of liver abscess have been reported.
  
  
  METHODS
  We reviewed the clinical data related to 94 patients with pyogenic liver abscess.
  
  
  RESULTS
  Of the 94 patients in the study group, the male to female ratio was 1.4:1 and the peak incidence of liver abscess was in the 7th decade. About three quarters (74.5%) of the abscesses were of unknown origin. The predominant location was in the right lobe (70.3%). Single lesion was found in 80 patients and multiple lesions in 14 patients. Pathogens were identified in 67 patients, of which Klebsiella pneumoniae (65.7%) and E. coli (16.4%) were the most common. The modalities of treatment were percutaneous drainage with antibiotics (73.4%), percutaneous aspiration with antibiotics (16.0%), or antibiotics alone (8.5%). The case fatality rate, mainly from associated underlying diseases, was 9 cases (9.6%). Associated diseases were diabetes mellitus (14.9%) and malignancy (10.6%).
  
  
  CONCLUSIONS
  Our study revealed that the most common organism was Klebsiella pneumoniae and percutaneous needle aspiration and/or catheter drainage were safe and effective treatment modalities for pyogenic liver abscess. Prognosis was determined by the underlying condition.
authors.affiliation: Department of Internal medicine, Chungnam National University College of Medicine, Daejeon, Korea.
authors.forename: Byung Kyu
authors.initials: BK
authors.lastname: Nah
authors.forename: Yeon Soo
authors.initials: YS
authors.lastname: Kim
authors.forename: Hee Seok
authors.initials: HS
authors.lastname: Moon
authors.forename: Ki Oh
authors.initials: KO
authors.lastname: Park
authors.forename: Sun Moon
authors.initials: SM
authors.lastname: Kim
authors.forename: Yeum Seok
authors.initials: YS
authors.lastname: Lee
authors.forename: Hyeon Woong
authors.initials: HW
authors.lastname: Yang
authors.forename: Seung Weon
authors.initials: SW
authors.lastname: Seo
authors.forename: Seok Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Byung Seok
authors.initials: BS
authors.lastname: Lee
authors.forename: Nam Jae
authors.initials: NJ
authors.lastname: Kim
authors.forename: Heon Young
authors.initials: HY
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D046290:Liver Abscess, Pyogenic / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged