title: [Elucidation of one-lobe intrapulmonary metastasis route of primary lung cancer by means of long-term results].
abstract: OBJECTIVE
  We hypothesized that the cause of one-lobe intrapulmonary metastasis of primary lung cancer is mainly lymphatic, and investigated by means of the long-term outcome.
  
  
  METHODS
  From 1988 to 2000, 860 patients underwent complete resection of primary lung cancer patients in our hospital without neoadjuvant therapy. Patients were classified into 4 groups: group A (n 0 pm 0, n = 573), group B (n 0 pm 1, n = 37), group C (n 1 pm 0-1, n = 122), and group D (n 2 pm 0-1, n = 128).
  
  
  RESULTS
  No significant difference was seen between groups in median age, sex ratio, histological cell type, or pathological tumor-size and p-factor. The rates of bi-lobectomy and pneumonectomy were higher in groups C and D than in groups A and B. The 5-year survival rate was 73% for group A, 57% for group B, 43% for group C, and 28% for group D. The 10-year survival rate was 57% for group A, 45% for group B, 20% for group C, and 16% for group D. There was a significant difference (p < 0.0001) between 4 groups in the 5- and 10-year survival rate.
  
  
  CONCLUSIONS
  The hypothesis that the cause of one-lobe intrapulmonary metastasis may be lymphatic was not incompatible with the long-term results.
authors.affiliation: Division of Thoracic Surgery, Nagaoka Red Cross Hospital, Nagaoka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Togashi
authors.forename: H
authors.initials: H
authors.lastname: Hirahara
authors.forename: M
authors.initials: M
authors.lastname: Sugawara
authors.forename: F
authors.initials: F
authors.lastname: Oguma
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015996:Survival Rate