title: Fibrosing mediastinitis and thrombosis of superior vena cava associated with Behçet's disease.
abstract: We present CT, MRI and venography findings in 13-year boy with mediastinal fibrosis and superior vena cava (SVC) thrombosis associated with Behçet's disease. Fibrosing mediastinitis is an excessive fibrotic reaction that occurs in the mediastinum and may lead to compression of mediastinal structures (especially vascular). This condition is usually idiopathic, though many (and perhaps most) cases in the USA are thought to be caused by an abnormal immunologic response to Histoplasma capsulatum infection. SVC syndrome secondary to extrinsic compression by mediastinal fibrosis combined with Behçet's disease has rarely been described. Radiological investigations of this syndrome are necessary to avoid a useless anticoagulant therapy.
authors.affiliation: Department of Radiology, University of Yuzuncu Yil, Faculty of Medicine, Van, Turkey. drmharman@hotmail.com
authors.forename: Mustafa
authors.initials: M
authors.lastname: Harman
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sayarlioglu
authors.forename: Halil
authors.initials: H
authors.lastname: Arslan
authors.forename: Hayati
authors.initials: H
authors.lastname: Ayakta
authors.forename: Ece
authors.initials: E
authors.lastname: Harman
mesh_terms: D000293:Adolescent; D001528:Behcet Syndrome / Q000150:complications*; D005355:Fibrosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008480:Mediastinitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014683:Vena Cava, Superior; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology*