title: Capillary chip based characterisation of small tissue samples.
abstract: There is a clear need for cell- and tissue-based test systems for in vitro diagnostics and therapy evaluation. The advantages of tissue-based test systems are that the complex cell response is taken into account and that proteins are in their natural environment. The capillary measurement cell enables impedance measurement of small tissue samples with negligible electrode impedances and a high constant shunt resistance so that biologically relevant tissue parameters are determinable.
authors.affiliation: Fraunhofer Institute for Biomedical Engineering, St Ingbert, Germany. hagen.thielecke@ibmt.fhg.de
authors.forename: Hagen
authors.initials: H
authors.lastname: Thielecke
mesh_terms: D002197:Capillary Action; D002468:Cell Physiological Phenomena; D003238:Connective Tissue / Q000502:physiology*; D046508:Culture Techniques / Q000295:instrumentation* / Q000379:methods; D017097:Electric Impedance; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design