title: Metastatic malignant solitary fibrous tumour to the infra-temporal fossa.
abstract: Malignant solitary fibrous tumours (MSFTs) are rare tumours of fibrous origin, which can occur at all anatomical sites and represent 20% of solitary fibrous tumours. Fine-needle aspiration cytology is not able to distinguish benign from malignant disease, and sufficient tissue has to be obtained for accurate histological diagnosis to be made. Lesions > 10 cm in diameter and incomplete resection or non-resectability are predictive factors for poor long-term survival. We present a 57-year-old patient with a presumably metastatic MSFT from the peritoneal cavity to the skull-base who is in a stable state 17 months after surgical debulking of the skull-base and removal of the peritoneal lesion, followed by post-operative chemotherapy. We suggest the terminology metastatic malignant solitary fibrous tumour for a description of this disease.
authors.affiliation: Department of Oral, Maxillofacial and Plastic Surgery, Klinikum Nord Tangstedter Landstrasse 400, 22417 Hamburg, Germany. suhr.mkg-heidberg@web.de
authors.forename: M
authors.initials: M
authors.lastname: Suhr
authors.forename: J
authors.initials: J
authors.lastname: Gottschalk
authors.forename: Th
authors.initials: T
authors.lastname: Kreusch
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007150:Immunohistochemistry; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000145:classification / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000473:pathology*; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D009626:Terminology as Topic
chemical_list: D018952:Antigens, CD34; D004317:Doxorubicin; D007069:Ifosfamide