Role of the extracellular matrix in prostate carcinogenesis.
This review summarizes the current state of knowledge regarding the proteins composing the extracellular matrix in the human prostate. The normal expression as well as the changes which occur in PIN and carcinoma are described for the lamins, collagens, and glycosaminoglycans.
Nagle
Ray B
RB
Arizona Cancer Center, University of Arizona, 1515 N. Campbell Avenue, Tucson, Arizona 85719, USA. rnagle@email.arizona.edu
D001485:Basement Membrane / Q000378:metabolism*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D005109:Extracellular Matrix / Q000378:metabolism*; D016326:Extracellular Matrix Proteins / Q000378:metabolism; D006801:Humans; D008297:Male; D011467:Prostate / Q000378:metabolism*; D019048:Prostatic Intraepithelial Neoplasia / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000378:metabolism*
D016326:Extracellular Matrix Proteins