Risk factors for premature coronary artery disease and determinants of adverse outcomes after revascularization in patients < or =40 years old.
Smoking is an important and modifiable risk factor associated with premature atherosclerosis and the need for coronary revascularization in young adult patients < or =40 years old. Although intermediate and long-term survival is better in young adult patients after percutaneous coronary intervention, co-morbidities such as low ejection fraction, previous myocardial infarction, and previous bypass surgery are important adverse prognostic determinants.
Mukherjee
Debabrata
D
Division of Cardiology, University of Michigan, Ann Arbor, Michigan, USA. dmukherj@umich.edu
Hsu
Amy
A
Moliterno
David J
DJ
Lincoff
A Michael
AM
Goormastic
Marlene
M
Topol
Eric J
EJ
D000328:Adult; D000367:Age Factors; D000800:Angioplasty, Balloon; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D009204:Myocardial Revascularization; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D015607:Stents