Characterization of early developments in the splenic leukocyte transcriptome of NOD mice.
Transcriptome analysis is a powerful tool to characterize changes in leukocyte gene expression patterns and reveal very early molecular abnormalities in tissue. Herein, we report on characterization of the very earliest abnormalities in the transcriptome of leukocytes from young "prepathologic" NOD and NON female mice.
Gerling
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Department of Medicine, University of Tennessee Health Science Center, and Research Service, Veterans Affairs Medical Center, Memphis, Tennessee 38104, USA. igerling@utmem.edu
Ali
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Lenchik
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D000818:Animals; D005260:Female; D020869:Gene Expression Profiling; D007962:Leukocytes / Q000378:metabolism*; D051379:Mice; D016688:Mice, Inbred NOD; D012333:RNA, Messenger / Q000235:genetics*; D013154:Spleen / Q000166:cytology*
D012333:RNA, Messenger