Morning glory syndrome and basal encephalocele.
BACKGROUND
Morning glory syndrome (MGS) is a congenital optic disc dysplasia often associated with craniofacial anomalies, especially basal encephalocele. Clinical presentations are varied and often occult.


METHODS
We describe a case of bilateral MGS associated with basal encephalocele that was detected by chance when treatment was sought for respiratory distress.


CONCLUSIONS
MGS and basal encephalocele should always be suspected in cases of midline deficiencies, particularly when ophthalmic signs of strabismus or poor vision are present. CT and MRI should be performed to delineate the extent of the lesion and a complete hormone screening should be carried out to exclude pituitary deficiency. The pathogenesis of MGS and basal encephalocele are unknown; however, it is thought to occur during the 5th week of embryonic development.
Chen
Celia S
CS
Department of Ophthalmology, Women's and Children's Hospital, 72 King William Road, SA 5006 North Adelaide, Australia. celiachen@bigpond.com
David
David
D
Hanieh
Ahmed
A
D004677:Encephalocele / Q000150:complications* / Q000473:pathology; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009305:Nasopharynx / Q000473:pathology; D009901:Optic Nerve Diseases / Q000150:complications* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods