Histopathologic comparison of normal and hyperplastic condyles.
OBJECTIVE
The aim of this study was to compare normal and hyperplastic mandibular condyles using two different histopathologic staining techniques.


METHODS
Nine cases of condylar hyperplasia and 13 normal cases were studied after hematoxylin and eosin and silver staining.


RESULTS
There was a significant difference between the two groups in the thickness of the hyperplastic cartilage layer of condylar soft tissue (P = 0.017). Also, the number of argyrophilic nucleolar organizer regions was significantly higher in the condylar hyperplasia case group (P = 0.0001). No significant differences could be demonstrated in cartilage island frequency, penetration depth, and distribution in the cancellous bone of condyles.


CONCLUSIONS
The thickness of the hyperplastic cartilage layer appears significantly increased in condylar hyperplasia. In addition, argyrophilic nucleolar organizer region count may be useful in histopathological identification of condylar hyperplasia.
Eslami
Behnam
B
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Evin, Tehran, Iran. behnameslami@yahoo.com
Behnia
Hossein
H
Javadi
Haleh
H
Khiabani
Kazem Savojbolaghchi
KS
Saffar
Arash Shoja
AS
D000293:Adolescent; D000328:Adult; D002356:Cartilage / Q000473:pathology; D016022:Case-Control Studies; D002467:Cell Nucleus / Q000648:ultrastructure; D004396:Coloring Agents; D004801:Eosine Yellowish-(YS); D005260:Female; D005355:Fibrosis; D005456:Fluorescent Dyes; D006416:Hematoxylin; D006801:Humans; D006818:Hyalin / Q000648:ultrastructure; D006965:Hyperplasia; D008297:Male; D008335:Mandibular Condyle / Q000473:pathology*; D008648:Mesoderm / Q000473:pathology; D009697:Nucleolus Organizer Region / Q000648:ultrastructure; D016622:Silver Staining; D018709:Statistics, Nonparametric
D004396:Coloring Agents; D005456:Fluorescent Dyes; D004801:Eosine Yellowish-(YS); D006416:Hematoxylin