Enzyme-facilitated enantioselective transport of (S)-ibuprofen through a supported liquid membrane based on ionic liquids.
Coupling lipase reactions with a supported liquid membrane (SLM) based on ionic liquids showed facilitative and selective permeation of (S)-ibuprofen through the SLM, indicating successful optical resolution of a racemic mixture using the enzyme-facilitative SLM.
Miyako
Eijiro
E
Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 6-10-1 Hakozaki, Higashiku, Fukuoka 812-8581, Japan.
Maruyama
Tatsuo
T
Kamiya
Noriho
N
Goto
Masahiro
M
D000818:Animals; D001692:Biological Transport; D002175:Candida / Q000201:enzymology; D007052:Ibuprofen / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism*; D007477:Ions / Q000737:chemistry; D008049:Lipase / Q000378:metabolism*; D012997:Solvents; D013237:Stereoisomerism; D013552:Swine
D007477:Ions; D012997:Solvents; D008049:Lipase; D007052:Ibuprofen