title: Feline plasma cell pododermatitis: a study of 8 cases.
abstract: Eight cases of feline plasma cell pododermatitis, collected over a 3-year period, were studied using histological (haematoxylin and eosin), histochemical (methyl green-pyronin) and immunohistochemical (antibody against lambda light chains of immunoglobulins) techniques. No sex, breed or age predisposition, or paw predilection was observed. The disease began as a swelling of the footpads, followed by ulceration. Histologically, lesions were characterized by the presence of a large number of plasma cells in a predominantly perivascular pattern. Binucleated plasma cells and mitotic figures were observed. Clinical follow-up for over 1 year revealed total remission of the lesions both after glucocorticoid therapy in four cases, and total surgical excision in two animals. Follow-up studies were not possible in one case.
authors.affiliation: ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Largo Prof Abel Salazar, Porto 4099-003, Portugal.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Dias Pereira
authors.forename: Augusto M R
authors.initials: AM
authors.lastname: Faustino
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D002415:Cats; D005260:Female; D005533:Foot Dermatoses / Q000453:epidemiology / Q000662:veterinary*; D006104:Granuloma, Plasma Cell / Q000453:epidemiology / Q000662:veterinary*; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D010950:Plasma Cells / Q000276:immunology; D011174:Portugal / Q000453:epidemiology; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies
chemical_list: D007147:Immunoglobulin Light Chains