Immunohistochemical localization of monoamine oxidase type B in the taste bud of the rat.
We have used immunohistochemistry to examine the subcellular localization of monoamine oxidase type B (MAO-B) in the taste bud of the rat circumvallate papilla. Electron microscopy showed that MAO-B was localized to the outer membranes of mitochondria in nerve terminals of afferent and efferent fibers, as well as in taste bud cells. MAO-B also existed on the mitochondrial outer membranes within myelinated and unmyelinated axons in the lamina propria beneath the taste bud. It is suggested that MAO-B-containing mitochondria are localized in peripheral branches and their terminals of sensory neurons for taste. The present study is the first to reveal the localization of MAO-B in sensory organs.
Xu
Yang
Y
Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
Ito
Akio
A
Arai
Ryohachi
R
D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000201:enzymology / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D013650:Taste Buds / Q000201:enzymology* / Q000648:ultrastructure
D008995:Monoamine Oxidase