title: Aptamer database.
abstract: The aptamer database is designed to contain comprehensive sequence information on aptamers and unnatural ribozymes that have been generated by in vitro selection methods. Such data are not normally collected in 'natural' sequence databases, such as GenBank. Besides serving as a storehouse of sequences that may have diagnostic or therapeutic utility, the database serves as a valuable resource for theoretical biologists who describe and explore fitness landscapes. The database is updated monthly and is publicly available at http://aptamer. icmb.utexas.edu/.
authors.affiliation: Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, University of Texas at Austin, 1 University Station A4800, Austin, TX 78712, USA.
authors.forename: Jennifer F
authors.initials: JF
authors.lastname: Lee
authors.forename: Jay R
authors.initials: JR
authors.lastname: Hesselberth
authors.forename: Lauren Ancel
authors.initials: LA
authors.lastname: Meyers
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Ellington
mesh_terms: D020029:Base Pairing; D001483:Base Sequence; D019295:Computational Biology; D030561:Databases, Nucleic Acid; D005818:Genetic Engineering; D020407:Internet; D009841:Oligonucleotides / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D016337:RNA, Catalytic / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D009841:Oligonucleotides; D016337:RNA, Catalytic