title: Mycotic ascending aortic pseudoaneurysm secondary to pseudomonas mediastinitis at the aortic cannulation site.
abstract: During the last 5 years, postoperative Pseudomonas mediastinitis has occurred in 2 of the 3,072 patients in our institution who have undergone cardiopulmonary bypass cardiac operations via a sternotomy. To our knowledge, there is no prior report in the English-language literature of postoperative Pseudomonas mediastinitis that originated at the aortic cannulation site, yet that was the site of origin in both of these patients. The 1st patient developed a mycotic pseudoaneurysm of the ascending aorta at the cannulation site, secondary to the development of Pseudomonas mediastinitis following aortic valve replacement. This sequela was successfully treated by means of aneurysmectomy and closure of the aorta with a bovine pericardial patch, under cardiopulmonary bypass with circulatory arrest. The 2nd patient developed pseudoaneurysm and perforation of the aorta at the cardioplegia needle site, secondary to Pseudomonas mediastinitis following aortic and mitral valve replacement. This patient died. In both patients, the cannulation site and the cardioplegia needle site had been closed with pledgeted sutures. Pseudomonas aeruginosa was cultured from both sites. Once the diagnosis of Pseudomonas mediastinitis is made following heart surgery, the patient should undergo reoperation, if possible, for removal of the foreign bodies (pledgeted sutures). In addition, these patients should be monitored with chest magnetic resonance angiography every 3 months for 1 year, in order to diagnose early development of a mycotic pseudoaneurysm and subsequent complications.
authors.affiliation: Rhode Island Hospital, Division of Cardiothoracic Surgery, Brown University School of Medicine, Providence, Rhode Island 02903, USA.
authors.forename: Dionisios
authors.initials: D
authors.lastname: Vrochides
authors.forename: William C
authors.initials: WC
authors.lastname: Feng
authors.forename: Arun K
authors.initials: AK
authors.lastname: Singh
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000209:etiology*; D000785:Aneurysm, Infected / Q000209:etiology*; D001018:Aortic Diseases / Q000209:etiology*; D002404:Catheterization / Q000009:adverse effects*; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000150:complications*; D011552:Pseudomonas Infections / Q000150:complications*