Posttranscriptional generation of macromolecular complexes.
Discrete classes of mRNAs that encode functionally related proteins are associated with sequence-specific RNA-binding proteins in yeast and mammalian cells. recently reported that pre-mRNAs encoding components of inhibitory synapses are bound to neuron-specific Nova RNA-binding proteins.
Keene
Jack D
JD
Center for RNA Biology, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
D000818:Animals; D000951:Antigens, Neoplasm; D005786:Gene Expression Regulation; D046911:Macromolecular Substances; D009419:Nerve Tissue Proteins / Q000378:metabolism; D000090682:Neuro-Oncological Ventral Antigen; D009474:Neurons / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D013569:Synapses / Q000502:physiology
D000951:Antigens, Neoplasm; D046911:Macromolecular Substances; D009419:Nerve Tissue Proteins; D000090682:Neuro-Oncological Ventral Antigen; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; D011956:Receptors, Cell Surface