DeltaNp73 stabilises TAp73 proteins but compromises their function due to inhibitory hetero-oligomer formation.
Slade
N
N
Zaika
A I
AI
Erster
S
S
Moll
U M
UM
D017398:Alternative Splicing; D000595:Amino Acid Sequence; D001859:Bone Neoplasms / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D045744:Cell Line, Tumor; D003513:Cycloheximide / Q000494:pharmacology; D004268:DNA-Binding Proteins; D019281:Dimerization; D017353:Gene Deletion; D017930:Genes, Reporter; D016147:Genes, Tumor Suppressor; D014644:Genetic Variation; D049452:Green Fluorescent Proteins; D006207:Half-Life; D006367:HeLa Cells; D006801:Humans; D008156:Luciferases / Q000378:metabolism; D008164:Luminescent Proteins; D009687:Nuclear Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000235:genetics*; D011401:Promoter Regions, Genetic; D020033:Protein Isoforms / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000235:genetics; D017434:Protein Structure, Tertiary / Q000235:genetics; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology; D012509:Sarcoma / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology; D015533:Transcriptional Activation; D000072160:Tumor Protein p73; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors* / Q000737:chemistry; D025521:Tumor Suppressor Proteins
D004268:DNA-Binding Proteins; D008164:Luminescent Proteins; D009687:Nuclear Proteins; D020033:Protein Isoforms; D011500:Protein Synthesis Inhibitors; D000072160:Tumor Protein p73; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; C000606369:delta Np73 protein, human; D049452:Green Fluorescent Proteins; D003513:Cycloheximide; D008156:Luciferases