title: Survey of gastric lesions and blood pepsinogen levels in pigs in Burkina Faso.
abstract: The purpose of the study was to investigate the prevalence of gastric lesions and to provide diagnostic values for serum pepsinogen in non-infected pigs and in pigs with gastric disease. In an abattoir survey, the pepsinogen concentrations were measured in the serum from 62 non-infected pigs, 33 pigs with gastric lesions and 17 pigs infected with Hyostrongylus rubidus, using a specific radioimmunoassay (RIA). The mean (+/- SE) pepsinogen concentrations in the serum of non-infected pigs, in pigs with gastric ulcers, and in pigs with a heavy H. rubidus infection were 630.8 +/- 39.2 ng/ml, 1084.5 +/- 166.2 ng/ml and 1095.2 +/- 102.3 ng/ml, respectively (p<0.05). Because of the higher concentrations of pepsinogen in the blood of pigs with gastric ulcers or parasitic infections, it is suggested that the measurement of serum pepsinogen by RIA may be an effective biochemical approach to the diagnosis of chronic gastric disorders in pigs.
authors.affiliation: Department of Physiology of Reproduction, Faculty of Veterinary Medicine, University of Liège, Bd de Colonster. no. 20 B41, 4000 Sart Tilman, Belgium.
authors.forename: H
authors.initials: H
authors.lastname: Banga-Mboko
authors.forename: H
authors.initials: H
authors.lastname: Tamboura
authors.forename: D
authors.initials: D
authors.lastname: Maes
authors.forename: H
authors.initials: H
authors.lastname: Traoré
authors.forename: I
authors.initials: I
authors.lastname: Youssao
authors.forename: P T
authors.initials: PT
authors.lastname: Sangild
authors.forename: B
authors.initials: B
authors.lastname: El Amiri
authors.forename: B
authors.initials: B
authors.lastname: Bayala
authors.forename: B
authors.initials: B
authors.lastname: Remy
authors.forename: J F
authors.initials: JF
authors.lastname: Beckers
mesh_terms: D000818:Animals; D002050:Burkina Faso / Q000453:epidemiology; D005753:Gastric Mucosa / Q000469:parasitology / Q000473:pathology; D020116:Pepsinogen A / Q000097:blood; D015995:Prevalence; D011863:Radioimmunoassay / Q000662:veterinary; D013276:Stomach Ulcer / Q000097:blood / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000097:blood* / Q000469:parasitology; D014251:Trichostrongyloidea / Q000302:isolation & purification*; D014252:Trichostrongyloidiasis / Q000097:blood / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*
chemical_list: D020116:Pepsinogen A