title: Crystal structure of the RC-LH1 core complex from Rhodopseudomonas palustris.
abstract: The crystal structure at 4.8 angstrom resolution of the reaction center-light harvesting 1 (RC-LH1) core complex from Rhodopseudomonas palustris shows the reaction center surrounded by an oval LH1 complex that consists of 15 pairs of transmembrane helical alpha- and beta-apoproteins and their coordinated bacteriochlorophylls. Complete closure of the RC by the LH1 is prevented by a single transmembrane helix, out of register with the array of inner LH1 alpha-apoproteins. This break, located next to the binding site in the reaction center for the secondary electron acceptor ubiquinone (UQB), may provide a portal through which UQB can transfer electrons to cytochrome b/c1.
authors.affiliation: Department of Chemistry, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: Aleksander W
authors.initials: AW
authors.lastname: Roszak
authors.forename: Tina D
authors.initials: TD
authors.lastname: Howard
authors.forename: June
authors.initials: J
authors.lastname: Southall
authors.forename: Alastair T
authors.initials: AT
authors.lastname: Gardiner
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Law
authors.forename: Neil W
authors.initials: NW
authors.lastname: Isaacs
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Cogdell
mesh_terms: D001059:Apoproteins / Q000737:chemistry; D001426:Bacterial Proteins / Q000737:chemistry*; D025541:Bacteriochlorophyll A / Q000737:chemistry; D001665:Binding Sites; D003460:Crystallization; D018360:Crystallography, X-Ray; D045342:Light-Harvesting Protein Complexes / Q000737:chemistry*; D046911:Macromolecular Substances; D008958:Models, Molecular; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry*; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D012241:Rhodopseudomonas / Q000737:chemistry*; D014451:Ubiquinone / Q000737:chemistry
chemical_list: D001059:Apoproteins; D001426:Bacterial Proteins; D025541:Bacteriochlorophyll A; D045342:Light-Harvesting Protein Complexes; D046911:Macromolecular Substances; D045322:Photosynthetic Reaction Center Complex Proteins; D014451:Ubiquinone