title: Neonatal intractable atrial flutter successfully treated with intravenous flecainide.
abstract: We present a neonatal case with intractable atrial flutter that did not respond to digitalization and electrical cardioversion. Intravenous flecainide administration completely resolved the atrial flutter. Proarrhythmic effects were not induced by flecainide administration. Although the efficacy of flecainide for atrial flutter during the infantile or childhood period is low, intravenous flecainide is worth consideration as a treatment for atrial flutter, even in intractable cases as described here, during the neonatal period.
authors.affiliation: Department of Pediatrics, Dokkyo University School of Medicine, 880, Kitakobayashi, Mibu, Shimotsuga-gun, Tochigi 321-0293, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Suzumura
authors.forename: A
authors.initials: A
authors.lastname: Nitta
authors.forename: M
authors.initials: M
authors.lastname: Ono
authors.forename: O
authors.initials: O
authors.lastname: Arisaka
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001282:Atrial Flutter / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D002304:Cardiac Pacing, Artificial; D004077:Digoxin / Q000627:therapeutic use; D018618:Echocardiography, Doppler, Color; D004554:Electric Countershock; D004562:Electrocardiography; D005260:Female; D005424:Flecainide / Q000008:administration & dosage / Q000627:therapeutic use*; D006329:Heart Conduction System / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D013318:Stroke Volume / Q000187:drug effects; D016216:Ultrasonography, Prenatal
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D005424:Flecainide