DnaSP, DNA polymorphism analyses by the coalescent and other methods.
CONCLUSIONS
DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (approximately 5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results.


BACKGROUND
The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp
Rozas
Julio
J
Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08071 Barcelona, Spain. jrozas@ub.edu.es
Sánchez-DelBarrio
Juan C
JC
Messeguer
Xavier
X
Rozas
Ricardo
R
D000465:Algorithms; D020869:Gene Expression Profiling / Q000379:methods*; D011110:Polymorphism, Genetic / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface