title: [A successful treatment with micafungin of candidemia due to Candida krusei].
abstract: We report a case of candidemia due to Candida krusei after subarachinoid hemorrhage. A 51 year-old male patient consulted us for high fever and increase of CRP 10 days post operation against subarachinoid hemorrhage. There was a temporary decrease in the CRP after administration of ceftazidime (CAZ) but it again when treatment with CAZ was stopped. Because of detected Candida sp. by blood culture, fluconazole was administered i.v. for 5 days, but C. krusei was positive during the treatment. Therefore, fluconazole was replaced with micafungin. The patient became better after the administration with micafungin for 14 days without side effect. Micafungin is effective against candidemia due to C. krusei.
authors.affiliation: Department of Infectious Diseases, Kitasato University School of Medicine.
authors.forename: Masato
authors.initials: M
authors.lastname: Nonoyama
authors.forename: Hikaru
authors.initials: H
authors.lastname: Kume
authors.forename: Ken
authors.initials: K
authors.lastname: Kumagai
authors.forename: Kazui
authors.initials: K
authors.lastname: Souma
authors.forename: Keisuke
authors.initials: K
authors.lastname: Sunakawa
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy*; D054714:Echinocandins; D016469:Fungemia / Q000188:drug therapy*; D006801:Humans; D055666:Lipopeptides; D008074:Lipoproteins / Q000627:therapeutic use*; D008297:Male; D000077551:Micafungin; D008875:Middle Aged; D010456:Peptides, Cyclic / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D008074:Lipoproteins; D010456:Peptides, Cyclic; D000077551:Micafungin