Farnesyltransferase inhibitors inhibit the growth of malaria parasites in vitro and in vivo.
Wiesner
Jochen
J
Biochemisches Institut der Justus-Liebig-Universität Giessen, Friedrichstrasse 24, 35392 Giessen, Germany.
Kettler
Katja
K
Sakowski
Jacek
J
Ortmann
Regina
R
Katzin
Alejandro M
AM
Kimura
Emília A
EA
Silber
Katrin
K
Klebe
Gerhard
G
Jomaa
Hassan
H
Schlitzer
Martin
M
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D000818:Animals; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D066298:In Vitro Techniques; D008958:Models, Molecular; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000254:growth & development
D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase