title: Electroanatomic mapping of the endocardium. Implication for catheter ablation of ventricular tachycardia.
abstract: The electroanatomic mapping system Carto((R)) with its combination of anatomic and electrophysiologic information has substantially improved our understanding of arrhythmia mechanisms and substrates in patients with ventricular tachycardia (VT) and structural heart disease. Identification of the individual arrhythmogenic substrate and successful ablation guided by the combination of sinus rhythm voltage mapping and conventional electrophysiologic techniques like pace and activation/entrainment mapping are best described for patients with recurrent VT in remote myocardial infarction. In about 75-90% of the patients, the target VT can be ablated with acute success and the patients remain free of any VT recurrence in up to 75%. First results of electroanatomically guided ablation in patients with arrhythmogenic right ventricular dysplasia are promising. Data on ablation of VT in other structural heart diseases are very limited, since the arrhythmogenic substrate is very diffuse, e. g., in dilated cardiomyopathy, or there are only small patient numbers, e. g., for cardiac sarcoidosis or monomorphic VT after repair of congenital heart disease. In this article, the current status of electroanatomically guided endocardial mapping and ablation of VT in patients with structural heart disease is described.
authors.affiliation: Cardiology, Department of Electrophysiology, Heart Center, University of Leipzig, Germany.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Wetzel
authors.forename: Gerhard
authors.initials: G
authors.lastname: Hindricks
authors.forename: Anja
authors.initials: A
authors.lastname: Dorszewski
authors.forename: Petra
authors.initials: P
authors.lastname: Schirdewahn
authors.forename: Jin-Hong
authors.initials: JH
authors.lastname: Gerds-Li
authors.forename: Christopher
authors.initials: C
authors.lastname: Piorkowski
authors.forename: Richard
authors.initials: R
authors.lastname: Kobza
authors.forename: Hildegard
authors.initials: H
authors.lastname: Tanner
authors.forename: Hans
authors.initials: H
authors.lastname: Kottkamp
mesh_terms: D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000503:physiopathology / Q000601:surgery; D018780:Body Surface Potential Mapping; D002311:Cardiomyopathy, Dilated / Q000150:complications; D017115:Catheter Ablation; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D004699:Endocardium / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications; D012008:Recurrence; D013318:Stroke Volume; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery*; D013997:Time Factors