title: Does wrist nerve block influence the result of botulinum toxin A treatment in palmar hyperhidrosis?
abstract: Treatment of palmar hyperhidrosis with intracutaneous injections of botulinum toxin type A is painful, making anesthesia desirable. However, nerve blocks may be associated with reduced efficacy. In 20 patients with idiopathic palmar hyperhidrosis both palms were treated with intracutaneous injections of botulinum toxin type A after having randomly chosen one hand for anesthesia by median und ulnar nerve block and the other hand for cooling. There was no difference in efficacy of botulinum toxin A treatment between both palms but significantly greater injection pain after cooling compared with nerve block.
authors.affiliation: Department of Dermatology, University of Würzburg, Germany.
authors.forename: Martina
authors.initials: M
authors.lastname: Hund
authors.forename: Stefan
authors.initials: S
authors.lastname: Rickert
authors.forename: Ilka
authors.initials: I
authors.lastname: Kinkelin
authors.forename: Markus
authors.initials: M
authors.lastname: Naumann
authors.forename: Henning
authors.initials: H
authors.lastname: Hamm
mesh_terms: D000293:Adolescent; D000328:Adult; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D014953:Wrist
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A