title: Modeling coincidence detection in nucleus laminaris.
abstract: A biologically detailed model of the binaural avian nucleus laminaris is constructed, as a two-dimensional array of multicompartment, conductance-based neurons, along tonotopic and interaural time delay (ITD) axes. The model is based primarily on data from chick nucleus laminaris. Typical chick-like parameters perform ITD discrimination up to 2 kHz, and enhancements for barn owl perform ITD discrimination up to 6 kHz. The dendritic length gradient of NL is explained concisely. The response to binaural out-of-phase input is suppressed well below the response to monaural input (without any spontaneous activity on the opposite side), implicating active potassium channels as crucial to good ITD discrimination.
authors.affiliation: Department of Electrical and Computer Engineering, University of Maryland, College Park, MD 20742, USA.
authors.forename: Victor
authors.initials: V
authors.lastname: Grau-Serrat
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Carr
authors.forename: Jonathan Z
authors.initials: JZ
authors.lastname: Simon
mesh_terms: D000818:Animals; D001306:Auditory Pathways / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology*; D002645:Chickens; D003198:Computer Simulation; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D013017:Sound Localization / Q000502:physiology*; D020305:Strigiformes