Prefrontal group II metabotropic glutamate receptor activation decreases performance on a working memory task.
Gregory
Mary L
ML
Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina, 29425, USA. gregorml@musc.edu
Stech
Nicholas E
NE
Owens
Russell W
RW
Kalivas
Peter W
PW
D000596:Amino Acids / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D018691:Excitatory Amino Acid Antagonists / Q000008:administration & dosage / Q000494:pharmacology; D005110:Extracellular Space / Q000187:drug effects / Q000378:metabolism; D005246:Feedback / Q000187:drug effects; D005971:Glutamates / Q000378:metabolism; D008570:Memory, Short-Term / Q000187:drug effects*; D008845:Microinjections; D017397:Prefrontal Cortex / Q000187:drug effects*; D011392:Proline / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D011597:Psychomotor Performance / Q000187:drug effects*; D051381:Rats; D018091:Receptors, AMPA / Q000819:agonists*; D014966:Xanthenes / Q000008:administration & dosage / Q000494:pharmacology
C097299:4-aminopyrrolidine-2,4-dicarboxylic acid; D000596:Amino Acids; D018691:Excitatory Amino Acid Antagonists; D005971:Glutamates; C114624:LY 341495; D018091:Receptors, AMPA; D014966:Xanthenes; D011392:Proline; C104722:glutamate receptor ionotropic, AMPA 2