title: Identification of the several new radicals formed in the reaction mixture of oxidized linoleic acid with ferrous ions using HPLC-ESR and HPLC-ESR-MS.
abstract: ESR, HPLC-ESR and HPLC-ESR-MS analyses were performed for the reaction mixtures of oxidized linoleic acid with ferrous ions combined use of spin trapping technique. More than 14 peaks were detected on the HPLC-ESR elution profile. In addition to 7-carboxyheptyl and pentyl radicals, several new radicals such as 7-carboxyldihydroxyheptyl, 1,5-dihydroxypentyl, 8-carboxy-1-hydroxyoctyl, 7-carboxy-1-hydroxyheptyl, 1-hydroxypentyl and 1-hydroxyhexyl were identified using HPLC-ESR and HPLC-ESR-MS.
authors.affiliation: Department of Chemistry, Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-8509, Japan. chem1@wakayama-med.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Iwahashi
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals / Q000032:analysis*; D007477:Ions / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D019787:Linoleic Acid / Q000737:chemistry*; D019097:Spin Trapping
chemical_list: D005609:Free Radicals; D007477:Ions; D019787:Linoleic Acid; D007501:Iron