title: LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system.
abstract: We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on the encoded proteins produced in functional genomics and proteomics approaches. The database also serves as a sample-tracking system to manage the process from cDNA to experimental read-out and data interpretation. A web interface enables the scientific community to explore and visualize features of the annotated cDNAs and ORFs combined with experimental results, and thus helps to unravel new features of proteins with as yet unknown functions.
authors.affiliation: German Cancer Research Center (DKFZ), Division of Molecular Genome Analysis, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany. d.bannasch@dkfz.de
authors.forename: Detlev
authors.initials: D
authors.lastname: Bannasch
authors.forename: Alexander
authors.initials: A
authors.lastname: Mehrle
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Glatting
authors.forename: Rainer
authors.initials: R
authors.lastname: Pepperkok
authors.forename: Annemarie
authors.initials: A
authors.lastname: Poustka
authors.forename: Stefan
authors.initials: S
authors.lastname: Wiemann
mesh_terms: D001331:Automation; D019295:Computational Biology; D018076:DNA, Complementary / Q000235:genetics*; D030541:Databases, Genetic; D023281:Genomics; D005858:Germany; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D016366:Open Reading Frames / Q000235:genetics; D011506:Proteins / Q000235:genetics* / Q000378:metabolism*; D040901:Proteomics
chemical_list: D018076:DNA, Complementary; D011506:Proteins