title: Effect of resistance training on changes in lymphocyte subpopulation during head-down-tilt bed rest.
abstract: Head-down-tilt (HDT) bed rest imitates microgravity-like conditions for a supine human body on the ground. On the other hand, resistance training is used to eliminate unfavorable physical changes in astronauts under a microgravity environment during spaceflight. Twelve healthy males voluntarily participated in a 20-day -6 degrees HDT bed rest study. The ratio of CD3-positive peripheral blood lymphocytes were analyzed by immunofluorescence staining. Volunteers who undertook resistance-training during HDT bed rest were designated as the resistance training group (RTG), and those who did not as non-resistance-training group (N-RTG). We could not observe significant differences in the ratio of CD3-positive peripheral blood lymphocytes between RTG and N-RTG. Thus, resistance training during HDT bed rest might not have a significant effect on changes in the ratios of CD3-positive PBL.
authors.affiliation: Graduate School of Medicine, The University of Tokyo.
authors.forename: Rie
authors.initials: R
authors.lastname: Wakimizu
authors.forename: Zheng
authors.initials: Z
authors.lastname: Chen
authors.forename: Hideoki
authors.initials: H
authors.lastname: Fukuoka
authors.forename: Nobuo
authors.initials: N
authors.lastname: Suzuki
authors.forename: Jun
authors.initials: J
authors.lastname: Nomura
mesh_terms: D000328:Adult; D001510:Bed Rest; D015444:Exercise / Q000502:physiology*; D018475:Head-Down Tilt; D006801:Humans; D016131:Lymphocyte Subsets / Q000502:physiology*; D008297:Male; D018474:Weightlessness Simulation