title: [Asynchronous occurrence of three neoplastic diseases: chronic B-cell lymphatic leukemia, renal carcinoma and prostatic adenocarcinoma].
abstract: Authors present a case of three asynchronous malignancies in man working life-long in chemical industry. Course of diseases and their treatment are described: B chronic lymphatic leukaemia (B-CLL) (age of 55), conventional clear cell renal carcinoma (CRCC) (age of 61) and adenocarcinoma of prostate (CaP) (age of 72). B-CLL treatment was chlorambucil for 2 years and follow-up subsequently. CRCC treatment was radical transperitoneal nephrectomy. Due to locally advanced CaP bilateral orchiectomy and radical external beam radiotherapy were performed. Patients is alive 30 months without any signs of any malignity. Incidence of multiple malignancies and particularly triplicities are discussed in this article. Authors point out pertinence of radical therapeutic approach also in multiple malignancies and oncological screening not only in patients with heamatological malignancy, but considering it in all tumours.
authors.affiliation: Urologická klinika, Fakultní nemocnice a Lékarské fakulty Univerzity Karlovy v Hradci Králové.
authors.forename: P
authors.initials: P
authors.lastname: Prosvic
authors.forename: P
authors.initials: P
authors.lastname: Dulícek
authors.forename: K
authors.initials: K
authors.lastname: Odrázka
authors.forename: J
authors.initials: J
authors.lastname: Navrátilová
authors.forename: P
authors.initials: P
authors.lastname: Morávek
authors.forename: P
authors.initials: P
authors.lastname: Macek
authors.forename: Z
authors.initials: Z
authors.lastname: Veselský
mesh_terms: D000230:Adenocarcinoma; D000368:Aged; D002292:Carcinoma, Renal Cell; D006801:Humans; D007680:Kidney Neoplasms; D015451:Leukemia, Lymphocytic, Chronic, B-Cell; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary; D011471:Prostatic Neoplasms