Fibrovascular changes misdiagnosed as cytomegalovirus retinitis reactivation in a patient with immune recovery.
A patient with human immunodeficiency virus infection and cytomegalovirus (CMV) retinitis developed immune recovery uveitis as a result of receipt of highly active antiretroviral therapy. Fibrovascular changes occurred in the CMV retinitis scar, were misdiagnosed as CMV retinitis reactivation, and were treated with anti-CMV medication. Fibrovascular membranes can be misdiagnosed as reactivated CMV retinitis, and a proper diagnosis is essential to avoid unnecessary therapy with potentially toxic antiviral medications.
Robinson
Michael R
MR
National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1863, USA. robinsonm@nei.nih.gov
Csaky
Karl G
KG
Lee
Susan S
SS
Masur
Henry
H
Polis
Michael A
MA
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology / Q000821:virology*; D000328:Adult; D017726:Cytomegalovirus Retinitis / Q000175:diagnosis* / Q000209:etiology; D003951:Diagnostic Errors; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male