title: Neurons and brain macrophages regulate connexin expression in cultured astrocytes.
abstract: Neurons and brain macrophages (BM), respectively, increase and inhibit gap junctional communication (GJC) and connexin expression in cultured astrocytes. Thus, in brain diseases and injuries, neuronal death associated with the BM activation may decrease GJC in astrocytes and therefore have a physiopathological relevance.
authors.affiliation: INSERM U114, Collège de France, Paris, France.
authors.forename: Annette
authors.initials: A
authors.lastname: Koulakoff
authors.forename: William
authors.initials: W
authors.lastname: Même
authors.forename: Charles-Felix
authors.initials: CF
authors.lastname: Calvo
authors.forename: Pascal
authors.initials: P
authors.lastname: Ezan
authors.forename: Nathalie
authors.initials: N
authors.lastname: Rouach
authors.forename: Christian
authors.initials: C
authors.lastname: Giaume
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000166:cytology / Q000378:metabolism*; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D002450:Cell Communication / Q000502:physiology; D017630:Connexins / Q000378:metabolism*; D017629:Gap Junctions / Q000378:metabolism; D008264:Macrophages / Q000166:cytology / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*
chemical_list: D017630:Connexins