title: Evaluation of the antibacterial potential of tetracycline or erythromycin mixed with calcium hydroxide as intracanal dressing against Enterococcus faecalis in vivo.
abstract: OBJECTIVE
  We evaluated the intracanal antibacterial potential of tetracycline or erythromycin mixed with calcium hydroxide (CH) against enterococci in vivo.
  
  
  METHODS
  Fifty-five teeth in which enterococci were present were dressed for 1 month with either tetracycline (28 teeth) or erythromycin (27 teeth) mixed with CH.
  
  
  RESULTS
  The tetracycline mixture was effective against enterococci in 22 teeth (79%). In 7 teeth, other microorganisms were recovered, resulting in a total antimicrobial effect of 54%. The corresponding results for erythromycin were 96% and 56%.
  
  
  CONCLUSIONS
  The antimicrobial treatment of CH in combination with either erythromycin or tetracycline had a significant effect on enterococci, but the overall antimicrobial effect was relatively weak. Erythromycin mixed with CH seems to be a valuable option in the battle against monoinfections of enterococci.
authors.affiliation: Department of Endodontology/Oral Diagnosis, Göteborg University, Sweden. a.molander@odontologi.gu.se
authors.forename: Anders
authors.initials: A
authors.lastname: Molander
authors.forename: Gunnar
authors.initials: G
authors.lastname: Dahlén
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000008:administration & dosage / Q000627:therapeutic use*; D015169:Colony Count, Microbial; D003786:Dental Pulp Cavity / Q000382:microbiology; D004202:Disinfectants / Q000008:administration & dosage / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000254:growth & development; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D018915:Root Canal Preparation; D013752:Tetracycline / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D004202:Disinfectants; D012387:Root Canal Filling Materials; D004917:Erythromycin; D013752:Tetracycline; D002126:Calcium Hydroxide