WormBase: a multi-species resource for nematode biology and genomics.
WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with extensively annotated views of the genome. The WormBase Consortium continues to expand the biological scope and utility of WormBase with the inclusion of large-scale genomic analyses, through active data and literature curation, through new analysis and visualization tools, and through refinement of the user interface. Over the past year, the nearly complete genomic sequence and comparative analyses of the closely related species Caenorhabditis briggsae have been integrated into WormBase, including gene predictions, ortholog assignments and a new synteny viewer to display the relationships between the two species. Extensive site-wide refinement of the user interface now provides quick access to the most frequently accessed resources and a consistent browsing experience across the site. Unified single-page views now provide complete summaries of commonly accessed entries like genes. These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system.
Harris
Todd W
TW
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. harris@cshl.org
Chen
Nansheng
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Cunningham
Fiona
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Tello-Ruiz
Marcela
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Antoshechkin
Igor
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Bastiani
Carol
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Bieri
Tamberlyn
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Blasiar
Darin
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Bradnam
Keith
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Chan
Juancarlos
J
Chen
Chao-Kung
CK
Chen
Wen J
WJ
Davis
Paul
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Kenny
Eimear
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Kishore
Ranjana
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Lawson
Daniel
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Lee
Raymond
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Muller
Hans-Michael
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Nakamura
Cecilia
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Ozersky
Philip
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Petcherski
Andrei
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Rogers
Anthony
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Sabo
Aniko
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Schwarz
Erich M
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Van Auken
Kimberly
K
Wang
Qinghua
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Durbin
Richard
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Spieth
John
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Sternberg
Paul W
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Stein
Lincoln D
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D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000235:genetics*; D019295:Computational Biology; D030541:Databases, Genetic; D023281:Genomics; D016247:Information Storage and Retrieval; D020407:Internet; D014584:User-Computer Interface