Recent improvements to the PROSITE database.
The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE web page has been redesigned and several tools have been implemented to help the user discover new conserved regions in their own proteins and to visualize domain arrangements. We also introduced the facility to search PDB with a PROSITE entry or a user's pattern and visualize matched positions on 3D structures. The latest version of PROSITE (release 18.17 of November 30, 2003) contains 1676 entries. The database is accessible at http://www.expasy.org/prosite/.
Hulo
Nicolas
N
Swiss Institute of Bioinformatics (SIB), CMU, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland. Nicolas.Hulo@isb-sib.ch
Sigrist
Christian J A
CJ
Le Saux
Virginie
V
Langendijk-Genevaux
Petra S
PS
Bordoli
Lorenza
L
Gattiker
Alexandre
A
De Castro
Edouard
E
Bucher
Philipp
P
Bairoch
Amos
A
D020816:Amino Acid Motifs; D000818:Animals; D019295:Computational Biology; D017124:Conserved Sequence; D030562:Databases, Protein; D006801:Humans; D020407:Internet; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D011786:Quality Control; D016415:Sequence Alignment; D013329:Structure-Activity Relationship
D011506:Proteins