Excellent enantio-selective enclathration of (2R,3S)-3-methyl-2-pentanol in channel-like cavity of 3-epideoxycholic acid, interpreted by the four-location model for chiral recognition.
Pure (2R,3S)-3-methyl-2-pentanol is resolved from the racemates by a steroidal host; the interpretation of the recognition mechanism based on the crystal structure reveals that CH/O interaction between the host and guest plays a decisive role in enantio-selective enclathration of the small aliphatic secondary alcohol.
Kato
Kazuaki
K
Department of Material anld Life Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. katochan@molrec.mls.eng.osaka-u.ac.jp
Aburaya
Kazuaki
K
Miyake
Yasuhito
Y
Sada
Kazuki
K
Tohnai
Norimitsu
N
Miyata
Mikiji
M