Ligand-selective signaling and high-content screening for GPCR drugs.
Gurwitz
David
D
Department of Human Genetics and Molecular Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Haring
Rachel
R
D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008024:Ligands; D008968:Molecular Conformation; D011812:Quinuclidines / Q000494:pharmacology; D043643:Receptor, Muscarinic M1 / Q000819:agonists; D043562:Receptors, G-Protein-Coupled / Q000819:agonists / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction; D013876:Thiophenes
D008024:Ligands; D011812:Quinuclidines; D043643:Receptor, Muscarinic M1; D043562:Receptors, G-Protein-Coupled; D013876:Thiophenes; C059240:cevimeline