title: [Complicated colon cancer: the experience at an Operative Surgery Unit].
abstract: BACKGROUND
  Prognosis of colon cancer is worse if complications are present at the moment of diagnosis. The high mortality rate with surgery in emergency in such cases needs a careful reflection about the best suitable operation to perform.
  
  
  METHODS
  107 consecutive patients observed along a 9 year-period for colon-rectal cancer are retrospectively analysed. 27 of them were complicated at the presentation for obstruction (19 patients), colon perforation (6 patients) or rectal hemorrhage (2 patients). In the whole experience 5 patients underwent primary resection of the tumour and direct anastomosis; 5 only a decompressive colostomy; 6 were primarily resected and anastomized under the protection of a cecostomy; 6 other patients underwent a Hartmann procedure; 2 were treated with only an intestinal by-pass; 1 was treated with Miles procedure; 1 with an anterior rectal section and the last one was resected-anastomosed in two steps, after a temporary decompressive colostomy.
  
  
  RESULTS
  Intraoperative mortality was of 11.1% (3 patients) and morbidity 18.5% (5 patients). General 5 years survival was 62.1% among the cases complicated at presentation. The recurrence rate was 8.45%. Both these figures are below a statistical significance (p = 0.57).
  
  
  CONCLUSIONS
  The necessity to treat in emergency the colon cancers reduces the possibility to adopt the best rules of modern programmed oncologic surgery giving up the chemotherapy w/o neoadjuvant radiotherapy with which a preoperative down-staging of the tumour were possible. For these reasons in emergency not only mortality and morbidity are higher than in case of elective surgery, but also metastasization and recurrence are worse because of a more difficult radicality in surgery.
authors.affiliation: Divisione Clinicizzata di Chirurgia Generale, Dipartimento di Scienze Chirurgiche Sperimentali e Cliniche, Università degli Studi G. d'Annunzio di Chieti.
authors.forename: E
authors.initials: E
authors.lastname: Mascitelli
authors.forename: M L
authors.initials: ML
authors.lastname: Vene
authors.forename: A
authors.initials: A
authors.lastname: Tauro
authors.forename: G
authors.initials: G
authors.lastname: Sigismondi
authors.forename: N
authors.initials: N
authors.lastname: Picardi
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000706:statistics & numerical data; D003108:Colonic Diseases / Q000453:epidemiology / Q000209:etiology; D003110:Colonic Neoplasms / Q000150:complications / Q000401:mortality / Q000601:surgery*; D003125:Colostomy / Q000706:statistics & numerical data; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology / Q000209:etiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007415:Intestinal Obstruction / Q000453:epidemiology / Q000209:etiology; D007416:Intestinal Perforation / Q000453:epidemiology / Q000209:etiology; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012189:Retrospective Studies; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data; D016019:Survival Analysis; D015996:Survival Rate