title: [Evaluation of serum sICAM-1 and sVCAM-1 concentration in patient at risk of preterm delivery].
abstract: Aim of the study was to assess the serum adhesion molecules concentration in patients at risk of preterm labour. Sixty-three patients were divided into two groups basing on cervical evaluation (Bishop's score > or = 6 and < 6). The assessment of sICAM-1 and sVCAM-1 levels in serum were carried out by immunoenzymatic ELISA test utilizing monoclonal antibodies (moAb) against human sICAM-1 and sVCAM-1 (ELISA system, R&Q, USA). Among the patients at risk of preterm labour and Bishop's score > or = 6 statistically higher serum levels of sICAM-1 were found. There were no statistically significant differences in sVCAM-1 levels between examined groups. We conclude that serum sICAM-1 determination might improve the prediction of preterm birth.
authors.affiliation: Kliniki Perinatologii i Połoznictwa AM w Białymstoku.
authors.forename: Remigiusz
authors.initials: R
authors.lastname: Urban
authors.forename: Adam
authors.initials: A
authors.lastname: Lemancewicz
authors.forename: Jan
authors.initials: J
authors.lastname: Urban
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kretowska
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D007752:Obstetric Labor, Premature / Q000276:immunology* / Q000517:prevention & control; D011044:Poland; D011237:Predictive Value of Tests; D011247:Pregnancy; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013997:Time Factors; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood*
chemical_list: D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1