title: SCF-mediated proteolysis and negative regulation in ethylene signaling.
abstract: Ethylene is an important hormonal regulator of plant growth that acts by regulating gene expression. In this issue of Cell, Guo and Ecker, and Potuschak et al., show that ethylene increases the abundance of the transcription factor EIN3, an activator of ethylene-inducible genes, by relieving its SCF-mediated destruction.
authors.affiliation: Department of Biology, University of York, YO10 5YW York, United Kingdom.
authors.forename: Stefan
authors.initials: S
authors.lastname: Kepinski
authors.forename: Ottoline
authors.initials: O
authors.lastname: Leyser
mesh_terms: D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; D005030:Ethylenes / Q000378:metabolism*; D025461:Feedback, Physiological / Q000235:genetics; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D010447:Peptide Hydrolases / Q000235:genetics / Q000378:metabolism; D063245:Plant Development; D010944:Plants / Q000235:genetics; D044843:SKP Cullin F-Box Protein Ligases / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D014157:Transcription Factors
chemical_list: D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; C106987:EIN3 protein, Arabidopsis; D005030:Ethylenes; D009687:Nuclear Proteins; D014157:Transcription Factors; C036216:ethylene; D044843:SKP Cullin F-Box Protein Ligases; D010447:Peptide Hydrolases