Examination of treatment pattern differences by race.
Examine differences in treatment patterns among Blacks and non-Blacks in the U.S. Schizophrenia Care and Assessment Program. Baseline data from medical record abstraction, participant self-report and clinical assessment used to examine differences by race (race-gender pairings) (n = 2,239). Descriptive and multivariate (logistic) analysis employed. More Blacks were diagnosed with paranoid subtype. Blacks exhibited a more negative PANSS composite score, lower quality of life scores, and higher AIMS scores than non-Blacks. There was no statistically significant difference in the number of outpatient visits or inpatient admissions between Blacks and non-Blacks. Blacks had lower medication adherence and received less second-generation agents and more antiparkinson/anticholinergic agents. Proportion of Black males receiving depot was greater than other race-gender pairings. Regression results indicate Blacks more likely to be prescribed only first-generations after controlling for depot (OR = 1.64; CI = 1.27-2.12; p = 0.0002). Schizophrenia is, on average, accompanied by different diagnoses and symptoms in Blacks. Symptom profiles indicate that second-generation antipsychotics may be underprescribed to Black patients.
Mark
Tami L
TL
Medstat, 4301 Connecticut Avenue, NW Suite 330, Washington, District of Columbia 20008, USA. tami.mark@medstat.com
Palmer
Liisa A
LA
Russo
Patricia A
PA
Vasey
Joseph
J
D001741:Black or African American / Q000523:psychology*; D000704:Analysis of Variance; D014150:Antipsychotic Agents / Q000145:classification / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008605:Mental Health Services / Q000706:statistics & numerical data; D010349:Patient Compliance / Q000208:ethnology*; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy* / Q000208:ethnology*; D012565:Schizophrenic Psychology; D012646:Self Administration; D012737:Sex Factors; D014481:United States; D044465:White People / Q000523:psychology
D014150:Antipsychotic Agents