title: A novel, repeated fed-batch, ethanol production system with extremely long term stability achieved by fully recycling fermented supernatants.
abstract: Using Saccharomyces cerevisiae, a novel, repeated fed-batch ethanol production system from corn flour by fully recycling fermented supernatants is demonstrated. With recovery of ethanol by evaporation coupled with consecutive removal of the insoluble and soluble inhibitory substances accumulated, either completely or partially by filtration, the concentrations of the soluble inhibitors in the system could be maintained at their equilibria. As a result, a sustained high concentration of ethanol (up to 15% v/v) and significant pollution control performance were obtained.
authors.affiliation: The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, PR China.
authors.forename: Xin
authors.initials: X
authors.lastname: Lu
authors.forename: Yongfei
authors.initials: Y
authors.lastname: Li
authors.forename: Zuoying
authors.initials: Z
authors.lastname: Duan
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Shi
authors.forename: Zhonggui
authors.initials: Z
authors.lastname: Mao
mesh_terms: D019149:Bioreactors / Q000382:microbiology*; D018929:Cell Culture Techniques / Q000379:methods*; D003198:Computer Simulation; D000431:Ethanol / Q000378:metabolism*; D005246:Feedback / Q000502:physiology; D005433:Flour / Q000382:microbiology*; D005947:Glucose / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000254:growth & development / Q000378:metabolism*; D014462:Ultrafiltration / Q000379:methods*
chemical_list: D000431:Ethanol; D005947:Glucose