[Radioimmunotherapy in patients with ovarian cancer in complete remission after the first line surgery and chemotherapy after second look laparoscopy procedure].
OBJECTIVE
The aim of the study was analysed a chance to successful radioimmunotherapy in patients with ovarian cancer as a consolidation procedure.


METHODS
Between 2000 and 2002 we introduced 56 patients into consolidation study with radioimmunotherapy after second look laparoscopy.


METHODS
17 patients during screening procedure have failed--mostly with positive CT scans (9/17). We have done 39 laparoscopies. Among 11 patients during laparoscopy we have found in 6 cases a residual disease and in 5 cases adhesions in abdomen or pelvis and this group was excluded from study. The remaining 28 patients were divided into two groups--14 in active and 14 in control arm.


RESULTS
Only 50% of patients with ovarian cancer in complete clinical remission after first line surgery and chemotherapy can be candidates to consolidation therapy. Among patients subjected to laparoscopy in 70% there was no evidence of macroscopic disease and adhesions.


CONCLUSIONS
Only 50% patients in complete clinical remission after first line surgery and chemotherapy have chance to successful radioimmunotherapy.
Markowska
Janina
J
Katedry Onkologii AM w Poznaniu.
Madry
Radosław
R
Kierzkowski
Jerzy
J
Malicki
Julian
J
Roszak
Andrzej
A
Lubin
Jolanta
J
Bratos
Krystyna
K
D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D020706:Laparoscopes; D010051:Ovarian Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D016499:Radioimmunotherapy / Q000379:methods; D012074:Remission Induction; D012189:Retrospective Studies; D024162:Second-Look Surgery / Q000295:instrumentation; D013997:Time Factors; D016896:Treatment Outcome
D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes