The EGL-13 SOX domain transcription factor affects the uterine pi cell lineages in Caenorhabditis elegans.
We isolated egl-13 mutants in which the pi cells of the Caenorhabditis elegans uterus initially appeared to develop normally but then underwent an extra round of cell division. The data suggest that egl-13 is required for maintenance of the pi cell fate.
Cinar
Hediye Nese
HN
Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.
Richards
Keri L
KL
Oommen
Kavita S
KS
Newman
Anna P
AP
D000595:Amino Acid Sequence; D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology / Q000235:genetics*; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D019070:Cell Lineage / Q000502:physiology*; D005260:Female; D008969:Molecular Sequence Data; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D014599:Uterus / Q000166:cytology*
D029742:Caenorhabditis elegans Proteins; C491546:EGL-13 protein, C elegans; D014157:Transcription Factors