Primary choriocarcinoma of the jejunum: report of a case.
We report a case of primary choriocarcinoma of the jejunum in a 45-year-old man, which was finally diagnosed by immunohistochemical analysis of a surgically resected specimen. Despite combined systemic chemotherapy, the patient died of progressive liver metastases 5 months after surgery. The serum human chorionic gonadotropin (HCG) level increased dramatically as the liver tumor progressed. According to our review of the 13 cases of primary or secondary choriocarcinoma of the small intestine reported in the English-language literature up until 2001, the characteristic symptoms are massive gastrointestinal bleeding and elevation of the serum HCG. Early diagnosis and prompt initiation of chemotherapy provide the only chance of improving the extremely poor prognosis associated with this rare neoplasm.
Iyomasa
Shinsuke
S
Department of Surgery, Social Insurance Chukyo Hospital, 1-1-10 Sanjo, Minami-ku, Nagoya 457-8510, Japan.
Senda
Yoshiki
Y
Mizuno
Keisuke
K
Miyake
Hideo
H
Amemiya
Takeshi
T
Yamaguchi
Junpei
J
Suzuki
Kazushi
K
Matsuda
Masao
M
D002822:Choriocarcinoma / Q000188:drug therapy / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D006063:Chorionic Gonadotropin / Q000097:blood; D017809:Fatal Outcome; D006801:Humans; D007580:Jejunal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D007583:Jejunum / Q000473:pathology; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged
D006063:Chorionic Gonadotropin