[Recent changes of organism and treatment in pyogenic liver abscess].
OBJECTIVE
With the advance of antibiotics and the development of newer imaging techniques, marked changes in etiology, diagnosis, treatment and prognosis of liver abscess have been reported.


METHODS
We reviewed the clinical data related to 94 patients with pyogenic liver abscess.


RESULTS
Of the 94 patients in the study group, the male to female ratio was 1.4:1 and the peak incidence of liver abscess was in the 7th decade. About three quarters (74.5%) of the abscesses were of unknown origin. The predominant location was in the right lobe (70.3%). Single lesion was found in 80 patients and multiple lesions in 14 patients. Pathogens were identified in 67 patients, of which Klebsiella pneumoniae (65.7%) and E. coli (16.4%) were the most common. The modalities of treatment were percutaneous drainage with antibiotics (73.4%), percutaneous aspiration with antibiotics (16.0%), or antibiotics alone (8.5%). The case fatality rate, mainly from associated underlying diseases, was 9 cases (9.6%). Associated diseases were diabetes mellitus (14.9%) and malignancy (10.6%).


CONCLUSIONS
Our study revealed that the most common organism was Klebsiella pneumoniae and percutaneous needle aspiration and/or catheter drainage were safe and effective treatment modalities for pyogenic liver abscess. Prognosis was determined by the underlying condition.
Nah
Byung Kyu
BK
Department of Internal medicine, Chungnam National University College of Medicine, Daejeon, Korea.
Kim
Yeon Soo
YS
Moon
Hee Seok
HS
Park
Ki Oh
KO
Kim
Sun Moon
SM
Lee
Yeum Seok
YS
Yang
Hyeon Woong
HW
Seo
Seung Weon
SW
Kim
Seok Hyun
SH
Lee
Byung Seok
BS
Kim
Nam Jae
NJ
Lee
Heon Young
HY
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D046290:Liver Abscess, Pyogenic / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged