[Concentration of thrombin activatable fibrinolysis inhibitor (TAFI) in cord blood and maternal blood during labor].
The concentration of TAFI in cord blood plasma has not been studied yet. We have measured its activity in plasma both in cord blood and mother's blood during labour. The study group consisted of 26 parturient women, 18 primiparas and 9 multiparas with normal course of pregnancy and delivery. Activity of TAFI was evaluated by chromogenic method (Actichrome Plasma TAFI Activity Kit). The level of TAFI in cord blood plasma was 4.20, range 3.80-6.40 micrograms/ml and in mother's blood 10.50, range 7.60-13.50 micrograms/ml, thus it was significantly lower (p < 0.0001).


CONCLUSIONS
TAFI is present in the cord blood plasma but its concentration is about 50% of that in the mother's blood.
Uszyński
Waldemar
W
Oddziału Połozniczo-Ginekologicznego, Wojewódzkiego Szpitala we Włocławku.
Zekanowska
Ewa
E
Szymański
Wiesław
W
Uszyński
Mieczysław
M
D000328:Adult; D025901:Carboxypeptidase B2 / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric / Q000097:blood*; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy; D012016:Reference Values
D025901:Carboxypeptidase B2