Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes.
Tang
Xing-Chun
XC
Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA. tangxc@musc.edu
Kalivas
Peter W
PW
D000596:Amino Acids / Q000494:pharmacology; D000818:Animals; D001253:Astrocytes / Q000187:drug effects / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism*; D003553:Cystine / Q000378:metabolism; D020536:Enzyme Activators / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D010770:Phosphotransferases / Q000037:antagonists & inhibitors / Q000378:metabolism; D011392:Proline / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D018094:Receptors, Metabotropic Glutamate / Q000819:agonists / Q000037:antagonists & inhibitors; D014966:Xanthenes / Q000494:pharmacology
C097299:4-aminopyrrolidine-2,4-dicarboxylic acid; D000596:Amino Acids; D002352:Carrier Proteins; D020536:Enzyme Activators; D004791:Enzyme Inhibitors; D018690:Excitatory Amino Acid Agonists; D018691:Excitatory Amino Acid Antagonists; C114624:LY 341495; D018094:Receptors, Metabotropic Glutamate; D014966:Xanthenes; C108822:metabotropic glutamate receptor 2; C102718:metabotropic glutamate receptor 3; D003553:Cystine; D011392:Proline; D010770:Phosphotransferases