title: [Management of bile duct injuries following laparoscopic cholecystectomy].
abstract: BACKGROUND
  The aim of the present study is to analyse our experience in the treatment of bile duct injury following laparoscopic cholecystectomy and to propose an algorithm for the management.
  
  
  METHODS
  From January 1990 to March 2002 175 patients with biliary tract injury sustained during laparoscopic cholecystectomy were treated at our institution. We divided the injuries into five basic types according to the mechanism, localisation and time of manifestation of the lesion. Risk factors affecting the outcome after operative repair were analysed by uni- and multivariate analysis.
  
  
  RESULTS
  There were 46 patients with peripheral bile leak (Type A). Endoscopic treatment was successful in 92 %. 8 patients presented with an occlusion of the common bile duct (CBD) (Type B). Five of 6 patients with an incomplete occlusion of the CBD could be treated by endoscopic options. Of 52 patients that presented a lateral lesion of the CBD (Type C), endoscopic treatment was successful in 35 patients (67 %), but surgical treatment was necessary in 17 (33 %). 27 patients with a complete transsection of the CBD required surgical reconstruction. Endoscopic treatment was successful in 34 of 42 patients with a late stenosis of the CBD. 11 of 55 patients (20 %) developed postoperative biliary complications. Univariate analysis identified three factors to be significant predictors of outcome: 1. attempts of repair before referral, 2. combined bile duct and hepatic artery injury, 3. Reconstruction in a situation of peritonitis. After a median follow-up of 44.6 months (2-109) a successful outcome was obtained in 51 of 55 (93 %) patients, including those requiring a secondary procedure for recurrent stricture.
  
  
  CONCLUSIONS
  Peripheral leakages, small lateral lesions and short stenosis usually can be treated endoscopically. Extended lateral injuries, complete CBD transsections and long stenoses require surgical therapy. For a successful therapy a specialized multidisciplinary team is crucial.
authors.affiliation: Charité Campus Virchow Klinikum, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie.
authors.forename: M
authors.initials: M
authors.lastname: Heise
authors.forename: S C
authors.initials: SC
authors.lastname: Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Adler
authors.forename: R E
authors.initials: RE
authors.lastname: Hintze
authors.forename: J M
authors.initials: JM
authors.lastname: Langrehr
authors.forename: P
authors.initials: P
authors.lastname: Neuhaus
mesh_terms: D000465:Algorithms; D000714:Anastomosis, Surgical; D001652:Bile Ducts / Q000293:injuries* / Q000601:surgery*; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D003135:Common Bile Duct / Q000293:injuries; D003627:Data Interpretation, Statistical; D004322:Drainage; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006499:Hepatic Artery / Q000293:injuries; D006500:Hepatic Duct, Common / Q000601:surgery; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008026:Ligation; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000150:complications; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome