title: Cardiovascular collapse after amiodarone administration in neonatal supraventicular tachycardia.
abstract: Amiodarone is recommended by the International Liaison Committee on Resuscitation and has been adapted by the Resuscitation Council (UK) and the Advanced Life Support Group for use in paediatric advanced life support and advanced paediatric life support for the treatment of refractory supraventricular tachycardia. The International Liaison Committee on Resuscitation has stated that resuscitation guidelines should be evidence based. We present a case report of a cardiovascularly stable infant with supraventricular tachycardia who had a variety of arrthymias requiring cardiopulmonary resucitation for a prolonged period of time after loading with intravenous amiodarone. We believe that this report, together with other evidence, may suggest caution with the use of amiodarone.
authors.affiliation: Department of Neonatology, St George's Hospital, Tooting, London, UK. drgytng@aol.com
authors.forename: Geraldine Y T
authors.initials: GY
authors.lastname: Ng
authors.forename: Darryl C
authors.initials: DC
authors.lastname: Hampson Evans
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Murdoch
mesh_terms: D000241:Adenosine / Q000008:administration & dosage; D000284:Administration, Oral; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004635:Emergency Medicine / Q000379:methods*; D015199:Extracorporeal Membrane Oxygenation; D006323:Heart Arrest / Q000150:complications / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D012769:Shock / Q000139:chemically induced* / Q000150:complications; D013617:Tachycardia, Supraventricular / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D000241:Adenosine; D000638:Amiodarone