Coronally positioned flap with or without enamel matrix protein derivative for the treatment of gingival recessions.
OBJECTIVE
To evaluate, histometrically, the healing of gingival recessions treated by coronally positioned flaps associated with enamel matrix protein derivative (EMD-Group) and to compare it to that obtained with coronally positioned flaps alone (CPF-Group).


METHODS
Five mongrel dogs were used. Gingival recessions were surgically created on the buccal aspect of the upper cuspids. The defects (5 x 7 mm) were exposed to plaque accumulation for 3 months. After a preparation period, the contralateral defects were randomly assigned to each group. After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, length of epithelium, new connective tissue attachment and new bone.


RESULTS
The gingival recession was -0.1 +/- 0.2 mm for the EMD-Group and -0.8 +/- 1.3 mm for the CPF-Group (P = 0.17). The extension of the epithelium was 1.2 +/- 1.0 mm for the EMD-Group and 1.3 +/- 0.7 mm for the CPF-Group (P = 0.89). The new connective tissue attachment was 4.8 +/- 0.7 in the EMD-Group and 4.0 +/- 1.4 in the CPF-Group (P = 0.22). The new bone was 0.1 +/- 1.8 mm and -0.5 +/- 1.4 mm in the EMD-Group and CPF-Group, respectively (P = 0.50). Histologically, the defect coverage observed was 98.2% for the EMD-Group and 85.8% for the CPF-Group.
Sallum
Enilson A
EA
Division of Periodontics, School of Dentistry at Piracicaba, University of Campinas, Piracicaba, SP, Brazil. easallum@fop.unicamp.br
Casati
Marcio Z
MZ
Caffesse
Raul G
RG
Funis
Leticia Perecin
LP
Nociti Júnior
Francisco H
FH
Sallum
Antônio W
AW
D000134:Acid Etching, Dental; D000539:Alveolar Process / Q000473:pathology; D000818:Animals; D003238:Connective Tissue / Q000473:pathology; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004285:Dogs; D004846:Epithelial Attachment / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005260:Female; D005889:Gingival Recession / Q000601:surgery*; D011897:Random Allocation; D018709:Statistics, Nonparametric; D013357:Subgingival Curettage; D013524:Surgical Flaps; D013997:Time Factors; D014945:Wound Healing
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins