title: Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs.
abstract: OBJECTIVE
  To determine the radiographic methods that best predict the development of osteoarthritis in the hip joints of a cohort of dogs with hip dysplasia and unaffected dogs.
  
  
  METHODS
  205 Labrador Retrievers, Greyhounds, and Labrador Retriever-Greyhound crossbred dogs.
  
  
  METHODS
  Pelvic radiography was performed when the dogs were 8 months old. Ventrodorsal extended-hip, distraction, and dorsolateral subluxation (DLS) radiographs were obtained. An Orthopedic Foundation for Animals-like hip score, distraction index, dorsolateral subluxation score, and Norberg angle were derived from examination of radiographs. Osteoarthritis was diagnosed at the time of necropsy in dogs > or = 8 months of age on the basis of detection of articular cartilage lesions. Multiple logistic regression was used to determine the radiographic technique or techniques that best predicted development of osteoarthritis.
  
  
  RESULTS
  A combination of 2 radiographic methods was better than any single method in predicting a cartilage lesion or a normal joint, but adding a third radiographic method did not improve that prediction. A combination of the DLS score and Norberg angle best predicted osteoarthritis of the hip joint or an unaffected hip joint. All models that excluded the DLS score were inferior to those that included it.
  
  
  CONCLUSIONS
  A combination of the DLS score and Norberg angle was the best predictor of radiographic measures in 8-month-old dogs to determine whether a dog would have normal or osteoarthritic hip joints.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Rory J
authors.initials: RJ
authors.lastname: Todhunter
authors.forename: Yjo T
authors.initials: YT
authors.lastname: Grohn
authors.forename: Stuart P
authors.initials: SP
authors.lastname: Bliss
authors.forename: Ashley
authors.initials: A
authors.lastname: Wilfand
authors.forename: Alma J
authors.initials: AJ
authors.lastname: Williams
authors.forename: Margaret
authors.initials: M
authors.lastname: Vernier-Singer
authors.forename: Nancy I
authors.initials: NI
authors.lastname: Burton-Wurster
authors.forename: Nathan L
authors.initials: NL
authors.lastname: Dykes
authors.forename: Rongling
authors.initials: R
authors.lastname: Wu
authors.forename: George
authors.initials: G
authors.lastname: Casella
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Acland
authors.forename: George
authors.initials: G
authors.lastname: Lust
mesh_terms: D000818:Animals; D002357:Cartilage Diseases / Q000000981:diagnostic imaging / Q000662:veterinary*; D004285:Dogs; D006619:Hip Dysplasia, Canine / Q000000981:diagnostic imaging*; D008962:Models, Theoretical; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000662:veterinary*; D011237:Predictive Value of Tests; D011859:Radiography