Phaeohyphomycosis caused by Chaetomium globosum in an allogeneic bone marrow transplant recipient.
Bone marrow transplant recipients are highly susceptible to opportunistic fungal infections. This is the report, of the first case of a Chaetomium systemic infection described in Brazil. A 34 year-old patient with chronic myeloid leukemia underwent an allogeneic sibling matched bone marrow transplant. Seven months later, he developed systemic infection with enlargement of the axillary and cervical lymph nodes. Culture of the aspirates from both lymph nodes yielded Chaetomium globosum. The infection was successfully treated with amphotericin B. The increasing population of immunosupressed patients requires a careful microbiologic investigation for uncommon fungal infections.
Teixeira
A B A
AB
Clinical Pathology Department, Universidade Estadual de Campinas-UNICAMP, Brazil.
Trabasso
P
P
Moretti-Branchini
M L
ML
Aoki
F H
FH
Vigorito
A C
AC
Miyaji
M
M
Mikami
Y
Y
Takada
M
M
Schreiber
A Z
AZ
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002597:Chaetomium / Q000302:isolation & purification*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery; D008198:Lymph Nodes / Q000382:microbiology; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology
D000935:Antifungal Agents; D000666:Amphotericin B