title: THGS: a web-based database of Transmembrane Helices in Genome Sequences.
abstract: Transmembrane Helices in Genome Sequences (THGS) is an interactive web-based database, developed to search the transmembrane helices in the user-interested gene sequences available in the Genome Database (GDB). The proposed database has provision to search sequence motifs in transmembrane and globular proteins. In addition, the motif can be searched in the other sequence databases (Swiss-Prot and PIR) or in the macromolecular structure database, Protein Data Bank (PDB). Further, the 3D structure of the corresponding queried motif, if it is available in the solved protein structures deposited in the Protein Data Bank, can also be visualized using the widely used graphics package RASMOL. All the sequence databases used in the present work are updated frequently and hence the results produced are up to date. The database THGS is freely available via the world wide web and can be accessed at http:// pranag.physics.iisc.ernet.in/thgs/ or http://144.16. 71.10/thgs/.
authors.affiliation: Bioinformatics Centre, Indian Institute of Science, Bangalore 560 012, India.
authors.forename: S A
authors.initials: SA
authors.lastname: Fernando
authors.forename: P
authors.initials: P
authors.lastname: Selvarani
authors.forename: Soma
authors.initials: S
authors.lastname: Das
authors.forename: Ch Kiran
authors.initials: ChK
authors.lastname: Kumar
authors.forename: Sukanta
authors.initials: S
authors.lastname: Mondal
authors.forename: S
authors.initials: S
authors.lastname: Ramakumar
authors.forename: K
authors.initials: K
authors.lastname: Sekar
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D019295:Computational Biology; D030562:Databases, Protein; D016678:Genome; D023281:Genomics; D006801:Humans; D020407:Internet; D008565:Membrane Proteins / Q000737:chemistry*; D017433:Protein Structure, Secondary; D040901:Proteomics; D012984:Software
chemical_list: D008565:Membrane Proteins