IntAct: an open source molecular interaction database.
IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains approximately 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.
Hermjakob
Henning
H
European Bioinformatics Institute, Hinxton, Cambridge CB10 1SD, UK. hhe@ebi.ac.uk
Montecchi-Palazzi
Luisa
L
Lewington
Chris
C
Mudali
Sugath
S
Kerrien
Samuel
S
Orchard
Sandra
S
Vingron
Martin
M
Roechert
Bernd
B
Roepstorff
Peter
P
Valencia
Alfonso
A
Margalit
Hanah
H
Armstrong
John
J
Bairoch
Amos
A
Cesareni
Gianni
G
Sherman
David
D
Apweiler
Rolf
R
D000818:Animals; D019295:Computational Biology; D030562:Databases, Protein; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D012984:Software; D014584:User-Computer Interface; D018875:Vocabulary, Controlled
D011506:Proteins