Electroanatomic mapping of transseptal conduction during coronary sinus pacing in patients with paroxysmal atrial fibrillation.
OBJECTIVE
To delineate the electrophysiological properties of transseptal conduction from the left to the right atrium in patients with paroxysmal atrial fibrillation (AF).


RESULTS
Right atrial mapping using the electroanatomic mapping technique was performed at 111 +/- 16 sites in 16 patients with paroxysmal AF during pacing from distal coronary sinus (CS). A single transseptal breakthrough near the CS ostium was observed in all patients. The activation time from the pacing site to the earliest septal activation site was 47 +/- 13 ms. The total septal activation time (68 +/- 16 ms) was markedly longer but the total right atrial activation time (118 +/- 17 ms) was similar to that in patients without AF in a previous observation.


CONCLUSIONS
During distal CS pacing, a preferential site of transseptal conduction near the CS ostium was demonstrated in patients with paroxysmal AF. This has clinical implications when surgical dissection or catheter ablation is considered to eliminate interatrial connection in patients with AF.
Hertervig
Eva
E
Department of Cardiology University Hospital, Lund University, Lund, Sweden.
Yuan
Shiwen
S
Liu
Shaowen
S
Kongstad
Ole
O
Luo
Jijian
J
Olsson
S Bertil
SB
D001281:Atrial Fibrillation / Q000503:physiopathology*; D018780:Body Surface Potential Mapping; D002304:Cardiac Pacing, Artificial; D003331:Coronary Vessels / Q000503:physiopathology; D022062:Electrophysiologic Techniques, Cardiac / Q000379:methods*; D005260:Female; D006325:Heart Atria / Q000033:anatomy & histology / Q000503:physiopathology; D006329:Heart Conduction System / Q000033:anatomy & histology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies