Palliative open heart surgery in an infant with factor VII deficiency.
An infant with factor VII deficiency underwent palliative open heart surgery for pulmonary atresia with an intact ventricular septum. No references had been found on the management of this rare coagulation disorder in infantile cardiac surgery. We describe the peri- and postoperative management with a replacement therapy including a recombinant factor VIIa concentrate. We conclude that an appropriate replacement therapy is needed to control bleeding during open heart surgery with factor VII deficiency.
Tokunaga
Chiho
C
Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba 305-8575, Japan.
Hiramatsu
Yuji
Y
Horigome
Hitoshi
H
Takahashi-Igari
Miho
M
Noma
Mio
M
Sakakibara
Yuzuru
Y
D006348:Cardiac Surgical Procedures; D005167:Factor VII / Q000008:administration & dosage; D005168:Factor VII Deficiency / Q000150:complications / Q000628:therapy; D015942:Factor VIIa; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010166:Palliative Care; D018633:Pulmonary Atresia / Q000150:complications / Q000601:surgery; D011994:Recombinant Proteins / Q000008:administration & dosage
D011994:Recombinant Proteins; D005167:Factor VII; C103587:recombinant FVIIa; D015942:Factor VIIa