title: Palladium-catalyzed highly regio- and stereoselective addition of organoboronic acids to allenes in the presence of AcOH.
abstract: The Pd(0)-catalyzed regio- and stereoselective addition of organoboronic acids to allenes leads to stereodefined tri- or tetrasubstituted alkenes. Furthermore, this method shows high substitutent-loading capability and tolerance of various substitutents. A hydropalladation-Suzuki coupling mechanism, which may account for the regio- and stereoselectivity, is proposed.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China. masm@mail.sioc.ac.cn
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma
authors.forename: Ning
authors.initials: N
authors.lastname: Jiao
authors.forename: Longwu
authors.initials: L
authors.lastname: Ye