title: Innovation and placebos in research: a new design of clinical trial.
authors.affiliation: Centre for Evaluation of Medicines, St Joseph's Healthcare, Hamilton, L8N 1G6, Ontario, Canada. holbrook@mcmaster.ca
authors.forename: Anne
authors.initials: A
authors.lastname: Holbrook
authors.forename: Charles
authors.initials: C
authors.lastname: Goldsmith
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D018849:Controlled Clinical Trials as Topic / Q000941:ethics / Q000379:methods* / Q000592:standards; D018592:Cross-Over Studies; D003866:Depressive Disorder / Q000188:drug therapy; D004311:Double-Blind Method; D006801:Humans; D015990:Placebo Effect; D010919:Placebos / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D012107:Research Design / Q000592:standards*; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D010919:Placebos