Thiazole orange as fluorescent universal base in peptide nucleic acids.
Thiazole orange is shown to possess characteristics of a universal base while maintaining duplex stability. Its fluorescence properties allowed distinction between matched and single mismatched hybridisation.
Köhler
Olaf
O
Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Str. 2, D-12489 Berlin, Germany.
Seitz
Oliver
O
D001483:Base Sequence; D052160:Benzothiazoles; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D020135:Peptide Nucleic Acids / Q000737:chemistry* / Q000235:genetics; D011804:Quinolines; D013050:Spectrometry, Fluorescence; D013844:Thiazoles / Q000737:chemistry*
D052160:Benzothiazoles; D005456:Fluorescent Dyes; D020135:Peptide Nucleic Acids; D011804:Quinolines; D013844:Thiazoles; C051000:thiazole orange