title: Osteosarcoma in Ga-Rankuwa Hospital: a 10 year experience in an African population.
abstract: OBJECTIVE
  This is a clinicopathological correlation of cases of osteosarcoma diagnosed and treated at Ga-Rankuwa Teaching Hospital.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  Department of Orthopaedics and Anatomical Pathology at Ga-Rankuwa/MEDUNSA Academic complex, a tertiary referral centre.
  
  
  METHODS
  66 patients with a diagnosis of osteosarcoma.
  
  
  METHODS
  Records of the bone tumour registry were reviewed and cases of osteosarcoma were identified. Slides were retrieved and the diagnoses confirmed in all the cases. Information pertaining to clinical presentation and patients' survival was obtained from the clinical records.
  
  
  RESULTS
  The patients' ages ranged from nine years to 75 years with a mean of 19.7 years (median 17 years). Most cases occurred around the knee and the male to female ratio was 2.7:1. The five year survival rate was 7.5% and only 25.8% survived for one year.
  
  
  CONCLUSIONS
  Our patients present with advanced disease leading to poor survival.
authors.affiliation: Department of Anatomical Pathology, Medical University of Southern Africa, P O Box 213, Medunsa.
authors.forename: M N
authors.initials: MN
authors.lastname: Muthuphei
authors.forename: M T
authors.initials: MT
authors.lastname: Mariba
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000671:Amputation, Surgical; D044383:Black People; D001859:Bone Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012516:Osteosarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011159:Population Surveillance; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D013019:South Africa / Q000453:epidemiology; D016019:Survival Analysis; D016896:Treatment Outcome