title: Tea intake and risk of colon cancer in African-Americans and whites: North Carolina colon cancer study.
abstract: OBJECTIVE
  Tea polyphenols have been shown to exhibit anti-cancer activity, but the epidemiological findings are inconsistent. We examined the association between tea consumption and colon cancer in a population-based study in North Carolina.
  
  
  METHODS
  The analysis included 630 cases and 1040 controls frequency matched to cases by age, gender, and race. The odds ratios (OR) for tea consumption, adjusted for age and gender, were calculated for African-Americans and Whites and effect modification by race was explored.
  
  
  RESULTS
  No association was found between tea consumption and colon cancer overall. Compared to non-consumers, those who consumed <2 servings/day or > or = 2 servings/day had OR = 0.9 (95% CI: 0.7-1.2) and OR = 1.3 (95% CI: 0.9-1.8) respectively. Other risk factors for colorectal cancer (family history of colorectal cancer, exposure to non-steroid anti-inflammatory drugs, meat cooking practices, smoking, physical activity, body mass index, intake of red meat, fruits, vegetables, and alcoholic beverages) did not influence these associations. We did not find any evidence of effect modification by race on either on the multiplicative or additive scale.
  
  
  CONCLUSIONS
  We conclude that, contrary to expectation, tea drinking did not decrease the risk of colon cancer in this study population.
authors.affiliation: Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA. dilyasov@wfubmc.edu
authors.forename: Dora
authors.initials: D
authors.lastname: Il'yasova
authors.forename: Christopher
authors.initials: C
authors.lastname: Martin
authors.forename: Robert S
authors.initials: RS
authors.lastname: Sandler
mesh_terms: D000328:Adult; D001741:Black or African American; D000368:Aged; D016022:Case-Control Studies; D003110:Colonic Neoplasms / Q000209:etiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009657:North Carolina; D016017:Odds Ratio; D012307:Risk Factors; D013662:Tea; D044465:White People
chemical_list: D013662:Tea