title: [Pilocytic astrocytoma in childhood: presentation of six cases].
abstract: OBJECTIVE
  To present 6 cases of pilocytic astrocytomas whose clinic, epidemiological and histopathological aspects were studied.
  
  
  METHODS
  Between 1990 and 1994 the records of the laboratories of pathology of the main hospitals in Curitiba were analysed and all cases of pilocytic astrocytomas were studied with special attention to age of onset, sex and site of the lesions. The biopsies, which were reviewed, have been processed according to conventional techniques and in a few cases electron microscopy and immunohistochemistry was further done.
  
  
  RESULTS
  Five patients were females and 1 was male. Medium age was 4,5 years (range 1-8). The pilocytic astrocytomas affected optic chiasm (n=3), midline of cerebral hemisfere (n=2) and third ventricle (n=1). The symptoms reflected the location and extension of the tumour. The commonest signs and symptoms were those of intracranial hypertension, visual disturbances, hydrocephalus, among others. The patients were treated with surgical ressection and chemotherapy. Three patients died after a medium survival of 45 days, and three remain alive.
  
  
  CONCLUSIONS
  The authors emphasize that pilocytic astrocytoma, mainly the juvenile variant, affect mostly the midline brain structures of infants through signs of visual disturbance. These lesions are low grade astrocytomas and should be treated predominantly by total surgical ressection.
authors.affiliation: Serviço de Anatomia Patológica do Hospital de Clínicas, UFPR.
authors.forename: L F
authors.initials: LF
authors.lastname: Torres
authors.forename: G V
authors.initials: GV
authors.lastname: Jacob
authors.forename: L
authors.initials: L
authors.lastname: de Noronha
authors.forename: B
authors.initials: B
authors.lastname: Werner
authors.forename: B C
authors.initials: BC
authors.lastname: Medeiros
authors.forename: E N
authors.initials: EN
authors.lastname: Vialle
authors.forename: L
authors.initials: L
authors.lastname: Ditzel