title: Novel alignment technique for LCD-biosensors.
abstract: The directional drying of a low-salt Tris-EDTA (TE)-buffer to give an alignment layer offers a simple, one-step, non-contact procedure for the construction of parallel liquid crystal displays (LCDs), which can be used to amplify the presence of DNA to scales visible to the naked eye, opening up possibilities for easy detection of bio recognition events.
authors.affiliation: NSRIM Institute, Toernooiveld 1, 6525ED, Nijmegen, The Netherlands.
authors.forename: Johan
authors.initials: J
authors.lastname: Hoogboom
authors.forename: Joost
authors.initials: J
authors.lastname: Clerx
authors.forename: Matthijs B J
authors.initials: MB
authors.lastname: Otten
authors.forename: Alan E
authors.initials: AE
authors.lastname: Rowan
authors.forename: Theo
authors.initials: T
authors.lastname: Rasing
authors.forename: Roeland J M
authors.initials: RJ
authors.lastname: Nolte
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D002021:Buffers; D004247:DNA / Q000032:analysis; D012680:Sensitivity and Specificity
chemical_list: D002021:Buffers; D004247:DNA