Venous thromboembolism. A review.
Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). A number of factors can increase VTE risk, including aging, smoking, immobility, pregnancy and a hereditary thrombophilia. Presenting symptoms are not definitive for DVT or PE, and objective testing is necessary for an accurate diagnosis. A number of antithrombolic agents are used in the prophylaxis and treatment of VTE. The current trend is toward using low-molecular-weight heparins instead of unfractionated heparin. There is increasing interest in new agents that can target a single factor in the coagulation cascade.
Thorneycroft
Ian H
IH
Departments of Obstetrics and Gynecology, University of South Alabama, Mobile, USA.
Goldzieher
Joseph W
JW
D000367:Age Factors; D000375:Aging; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D008019:Life Style; D008297:Male; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012307:Risk Factors; D012907:Smoking; D013923:Thromboembolism / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D019851:Thrombophilia; D014481:United States; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight