title: The Database of Interacting Proteins: 2004 update.
abstract: The Database of Interacting Proteins (http://dip.doe-mbi.ucla.edu) aims to integrate the diverse body of experimental evidence on protein-protein interactions into a single, easily accessible online database. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks.
authors.affiliation: Howard Hughes Medical Institute, UCLA-DOE Institute for Genomics and Proteomics, 90095-1570, USA.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Salwinski
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Miller
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Smith
authors.forename: Frank K
authors.initials: FK
authors.lastname: Pettit
authors.forename: James U
authors.initials: JU
authors.lastname: Bowie
authors.forename: David
authors.initials: D
authors.lastname: Eisenberg
mesh_terms: D000818:Animals; D019295:Computational Biology; D030562:Databases, Protein; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D046911:Macromolecular Substances; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D015203:Reproducibility of Results
chemical_list: D046911:Macromolecular Substances; D011506:Proteins