title: Hiccups attributable to syringobulbia and/or syringomyelia associated with a Chiari I malformation: case report.
abstract: OBJECTIVE
  Approximately 20 to 50% of patients with syringomyelia associated with Chiari malformations exhibit cranial nerve or cerebellar symptoms. However, hiccups represent a rare clinical manifestation of this disorder. We report a case of intractable hiccups resulting from syringobulbia associated with a Chiari I malformation, which was successfully treated with foramen magnum decompression.
  
  
  METHODS
  We report the case of a patient who presented with syringomyelia and syringobulbia associated with a Chiari I malformation, manifested as intractable hiccups and neurological deficits. Magnetic resonance imaging scans demonstrated syringobulbia in the dorsal medullary region and a large cervical syrinx from C2 to C6-C7, associated with a Chiari I malformation.
  
  
  METHODS
  Foramen magnum decompression and a C1 laminectomy were performed. One month later, the intractable hiccups disappeared and the neurological symptoms demonstrated improvement.
  
  
  CONCLUSIONS
  Postoperative magnetic resonance imaging scans demonstrated enlargement of the subarachnoid space in the posterior fossa and disappearance of the syringobulbia. There has been no recurrence of intractable hiccups and syringobulbia in 6 months after surgery. Magnetic resonance imaging of the brainstem is an important diagnostic procedure for intractable hiccups, because syringobulbia associated with a Chiari malformation represents a surgically treatable disorder, although the incidence is low.
authors.affiliation: Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan. toseki@med.hokudai.ac.jp
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Seki
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Hida
authors.forename: JangBo
authors.initials: J
authors.lastname: Lee
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Iwasaki
mesh_terms: D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications*; D006606:Hiccup / Q000209:etiology*; D006801:Humans; D008297:Male; D013595:Syringomyelia / Q000150:complications*