A rationally designed novel receptor for probing cooperative interaction between metal ions and bivalent tryptophan side chain in solution.
Cooperative interactions between metal ions and bivalent tryptophan side chain are identified in water by fluorescence quenching of a designed novel receptor, EDTA-bis(L-tryptophan methyl ester), supplemented by a circular dichroism study; results revealed that the receptor is capable of distinguishing a variety of metal ions on the basis of their abilities in quenching tryptophan fluorescence and the relative magnitude of these interactions is Cu2+ approximately Fe2+ >> Co2+ > Ni2+ >> Mn2+ > Zn2+ > La3+ > Al3+.
Li
Yitong
Y
Neurochemistry and Physical Organic Chemistry, Nankai University, Tianjin 300071, China.
Yang
Chi Ming
CM
D002412:Cations / Q000737:chemistry*; D002942:Circular Dichroism; D004492:Edetic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D005453:Fluorescence; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D012996:Solutions / Q000737:chemistry; D014364:Tryptophan / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D002412:Cations; C488477:EDTA-bis(L-tryptophan methyl ester); D008670:Metals; D012996:Solutions; D014867:Water; D014364:Tryptophan; D004492:Edetic Acid