Synthesis of enantiomerically enriched oxazolinyl[1,2]oxazetidines.
The first stereoselective synthesis of oxazolinyl[1,2]oxazetidines based on the reaction of lithiated 2-(1-chloroethyl)-2-oxazolines with nitrones is described. Highly enantioenriched oxazolinyl[1,2]oxazetidines have also been prepared starting from a 1:1 diastereomeric mixture of optically active 2-(1-chloroethyl)-2-oxazolines.
Luisi
Renzo
R
Dipartimento Farmaco-Chimico, Università di Bari, Via E. Orabona 4, I-70126 Bari, C.N.R., Istituto di Chimica dei Composti OrganoMetallici ICCOM, Sezione di Bari, Italy.
Capriati
Vito
V
Florio
Saverio
S
Piccolo
Eliana
E