title: MRI texture analysis on texture test objects, normal brain and intracranial tumors.
abstract: Texture analysis was performed in three different MRI units on T1 and T2-weighted MR images from 10 healthy volunteers and 63 patients with histologically confirmed intracranial tumors. The goal of this study was a multicenter evaluation of the usefulness of this quantitative approach for the characterization of healthy and pathologic human brain tissues (white matter, gray matter, cerebrospinal fluid, tumors and edema). Each selected brain region of interest was characterized with both its mean gray level values and several texture parameters. Multivariate statistical analyses were then applied in order to discriminate each brain tissue type represented by its own set of texture parameters. Texture analysis was previously performed on test objects to evaluate the method dependence on acquisition parameters and consequently the interest of a multicenter evaluation. Even obtained on different sites with their own acquisition routine protocol, MR brain images contain textural features that can reveal discriminant factors for tissue classification and image segmentation. It can also offer additional information in case of undetermined diagnosis or to develop a more accurate tumor grading.
authors.affiliation: LRMBM-IFR 91, Faculté de Médecine, Rennes, France. sandra.herlidou@u-picardie.fr
authors.forename: S
authors.initials: S
authors.lastname: Herlidou-Même
authors.forename: J M
authors.initials: JM
authors.lastname: Constans
authors.forename: B
authors.initials: B
authors.lastname: Carsin
authors.forename: D
authors.initials: D
authors.lastname: Olivie
authors.forename: P A
authors.initials: PA
authors.lastname: Eliat
authors.forename: L
authors.initials: L
authors.lastname: Nadal-Desbarats
authors.forename: C
authors.initials: C
authors.lastname: Gondry
authors.forename: E
authors.initials: E
authors.lastname: Le Rumeur
authors.forename: I
authors.initials: I
authors.lastname: Idy-Peretti
authors.forename: J D
authors.initials: JD
authors.lastname: de Certaines
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000033:anatomy & histology* / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012680:Sensitivity and Specificity