The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin.
Advances over the past decade suggest a need to reassess the distribution of ovarian surface epithelial tumors. A series of 220 consecutive invasive ovarian carcinomas, including carcinosarcomas and peritoneal carcinomas, was reviewed. Notable findings include: 7% of tumors were carcinosarcomas; 22% of cases of peritoneal serous carcinomatosis were of peritoneal origin; <3% of cases were mucinous carcinomas; and only one malignant Brenner tumor (0.5%) and no pure transitional cell carcinomas were identified. If peritoneal carcinomas, carcinosarcomas, and mixed carcinomas with a serous component are combined with serous carcinomas, this group accounts for 78% of all cases and 87% of advanced stage cases, suggesting a greater uniformity to epithelial ovarian cancer than previously appreciated.
Seidman
Jeffrey D
JD
Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA. Jeffrey.D.Seidman@medstar.net
Horkayne-Szakaly
Iren
I
Haiba
Moutaz
M
Boice
Charles R
CR
Kurman
Robert J
RJ
Ronnett
Brigitte M
BM
D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology*; D012189:Retrospective Studies