title: An uncommon cause of fever in the elderly: late-onset systemic lupus erythematosus.
abstract: Infections, tumors and multisystem disease are common causes of fever of unknown origin (FUO) in the elderly. Late-onset systemic lupus erythematosus (LO-SLE) is a very rare cause of FUO in elderly patients. Serositis and musculoskeletal manifestations are common, but fever as an initial manifestation in LO-SLE is rare. We present two patients with LO-SLE who manifested fever as an initial symptom. Fever was the only symptom for 2 months in the first case and for 3 months in the second. In conclusion, in geriatric patients who have fever, LO-SLE should be considered in the differential diagnosis.
authors.affiliation: Department of Internal Medicine, Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Esin
authors.initials: E
authors.lastname: Beyan
authors.forename: Aysel
authors.initials: A
authors.lastname: Uzuner
authors.forename: Cengiz
authors.initials: C
authors.lastname: Beyan
mesh_terms: D000368:Aged; D002738:Chloroquine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005335:Fever of Unknown Origin / Q000188:drug therapy / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D002738:Chloroquine; D011241:Prednisone