title: Carotid artery revascularization.
abstract: Stroke is the third leading cause of death in the United States, and up to one third of patients have a stroke secondary to carotid occlusive disease. Surgical management has firmly established itself as an important modality in treating this disease. Several prospective randomized trials have defined the patients that would have the most benefit from carotid endarterectomy (CEA). These patient populations include asymptomatic patients with a >or= 60% stenosis and symptomatic patients with a >or= 50% stenosis. The timing of CEA after stroke remains controversial, but recent studies advocate early CEA in a select group of patients. During the CEA, the method of closing of the arteriotomy has an overall effect on the safety of the procedure as well as long-term outcome. As compared with primary repair of the arteriotomy, patch closure has been shown to decrease the frequency of restenosis. In addition, carotid eversion endarterectomy (CEE) is an alternative method to remove the plaque that has a similar efficacy to standard CEA. The role of carotid angioplasty and stenting (CAS) continues to evolve and offers the patient a less invasive method of treating the carotid plaque.
authors.affiliation: Department of Vascular Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Vijungco
authors.forename: William H
authors.initials: WH
authors.lastname: Pearce
mesh_terms: D016893:Carotid Stenosis / Q000150:complications* / Q000601:surgery*; D002548:Cerebral Revascularization / Q000379:methods*; D016894:Endarterectomy, Carotid / Q000379:methods*; D006801:Humans; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D015607:Stents; D020521:Stroke / Q000209:etiology / Q000517:prevention & control*