title: A rationally designed novel receptor for probing cooperative interaction between metal ions and bivalent tryptophan side chain in solution.
abstract: Cooperative interactions between metal ions and bivalent tryptophan side chain are identified in water by fluorescence quenching of a designed novel receptor, EDTA-bis(L-tryptophan methyl ester), supplemented by a circular dichroism study; results revealed that the receptor is capable of distinguishing a variety of metal ions on the basis of their abilities in quenching tryptophan fluorescence and the relative magnitude of these interactions is Cu2+ approximately Fe2+ >> Co2+ > Ni2+ >> Mn2+ > Zn2+ > La3+ > Al3+.
authors.affiliation: Neurochemistry and Physical Organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Yitong
authors.initials: Y
authors.lastname: Li
authors.forename: Chi Ming
authors.initials: CM
authors.lastname: Yang
mesh_terms: D002412:Cations / Q000737:chemistry*; D002942:Circular Dichroism; D004492:Edetic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D005453:Fluorescence; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D012996:Solutions / Q000737:chemistry; D014364:Tryptophan / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D002412:Cations; C488477:EDTA-bis(L-tryptophan methyl ester); D008670:Metals; D012996:Solutions; D014867:Water; D014364:Tryptophan; D004492:Edetic Acid