title: An assessment of the severity of recurrent appendicitis.
abstract: BACKGROUND
  This study examines the clinical characteristics of patients who developed recurrent appendicitis after previous nonoperative management of perforated appendicitis.
  
  
  METHODS
  Retrospective chart review was performed, and data from the recurrent and initial episode of appendicitis were collected.
  
  
  RESULTS
  In all, 237 patients from 1989 to 2001 were managed nonoperatively for perforated appendicitis and 32 (14%) were readmitted for recurrent appendicitis. Median white blood cell count at recurrence was 9.5 (interquartile range [IQR]: 6.6 to 13.2] versus 13.1 [IQR: 10.8 to 16.1] at initial presentation (P = 0.002). Maximum temperature was 98.6 degrees F [IQR: 98.2 to 100.5] at recurrence versus 100.3 degrees F [IQR: 99.5 to 101.5] (P = 0.008). Median time for intravenous antibiotics use was 3 [IQR: 3 to 7] days at recurrence versus 6 [IQR: 4 to 8] days initially (P = 0.01). Inpatient stay was also shorter; median length was 6 [IQR: 3 to 8] days compared with 7 [IQR: 5 to 9] days at initial presentation (P = 0.02).
  
  
  CONCLUSIONS
  Patients managed nonoperatively for perforated appendicitis who later developed recurrent appendicitis exhibited a milder clinical course at recurrence. Elective interval appendectomy may be reserved until a recurrent episode.
authors.affiliation: Division of Colon and Rectal Surgery, Harbor-UCLA Medical Center, Torrance, CA, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Dixon
authors.forename: Jason S
authors.initials: JS
authors.lastname: Haukoos
authors.forename: Ina U
authors.initials: IU
authors.lastname: Park
authors.forename: David
authors.initials: D
authors.lastname: Oliak
authors.forename: Ravin R
authors.initials: RR
authors.lastname: Kumar
authors.forename: Tracey D
authors.initials: TD
authors.lastname: Arnell
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Stamos
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001062:Appendectomy; D001064:Appendicitis / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D000900:Anti-Bacterial Agents