Immunopotentiating properties of Cryptolepis buchanani root extract.
The ethanol extract (95%) of the root of the plant Cryptolepis buchanani (EECB) was investigated for immunomodulatory activity in mice and rats. The oral administration of EECB caused significant stimulation of the delayed type hypersensitivity (DTH) reaction and humoral antibody production. The oral LD50 was found to be more than 3 g/kg in both rats and mice.
Kaul
Anpurna
A
Department of Pharmacology, Regional Research Laboratory, Jammu Tawi, 180 001, India.
Bani
Sarang
S
Zutshi
Usha
U
Suri
K A
KA
Satti
N K
NK
Suri
O P
OP
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001170:Arthritis, Infectious / Q000517:prevention & control; D031106:Cryptolepis; D004305:Dose-Response Relationship, Drug; D006968:Hypersensitivity, Delayed / Q000517:prevention & control; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D051381:Rats
D000276:Adjuvants, Immunologic; D010936:Plant Extracts