title: Acute hemorrhagic edema of infancy: a case report.
abstract: BACKGROUND
  Acute hemorrhagic edema of infancy (AHEI), or Seidlmayer's disease, is a type of leukocytoclastic vasculitis proper of infants and children. It is characterized by a local increase in temperature, erythematous edema and purpuric lesions involving mainly the face and extremities. There usually is no visceral involvement. The disease is self-limited, bearing a benign clinical course. Infection, drugs and immunization have been considered as precipitating factors. The main differential diagnosis is Henoch-Schönlein purpura (HSP).
  
  
  METHODS
  We describe a classic example of acute hemorrhagic edema of infancy, and comment on the clinical features, pathology, immunopathology and proposed therapy. We characterize the differences between AHEI and HSP.
  
  
  RESULTS
  A course of corticosteroids was given to avoid quick progression of disease.
  
  
  CONCLUSIONS
  Acute hemorrhagic edema of infancy is a rare disease, and the most striking classic feature of the disease is the contrast between the acuteness of the cutaneous lesions and the good general condition of the patient. Considering its clinical features, pathology and immunopathology, AHEI can be justifiably characterized as a unique disorder, distinct from HSP.
authors.affiliation: Department of Dermatology, Hospital de Clinicas de Porto Alegre, Brazil. apds@cpovo.net
authors.forename: Ana Paula Dornelles
authors.initials: AP
authors.lastname: da Silva Manzoni
authors.forename: Josiane Burmann
authors.initials: JB
authors.lastname: Viecili
authors.forename: Cristiane Benvenuto
authors.initials: CB
authors.lastname: de Andrade
authors.forename: Ricardo Lapa
authors.initials: RL
authors.lastname: Kruse
authors.forename: Lucio
authors.initials: L
authors.lastname: Bakos
authors.forename: Tania Ferreira
authors.initials: TF
authors.lastname: Cestari
mesh_terms: D000208:Acute Disease; D004487:Edema / Q000175:diagnosis*; D006470:Hemorrhage / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008297:Male; D012871:Skin Diseases / Q000175:diagnosis*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis*