title: A late complication of pelvic radiotherapy: leiomyosarcoma of the rectum. Report of a case and review of the literature.
abstract: Leiomyosarcoma of the rectum is an uncommon malignancy; it accounts for less than 0.1% of all malignancies of the colon and rectum and only one case has been reported long-term following pelvic radiotherapy. We report a second case of leiomyosarcoma of the rectum after radiotherapy in an elderly women who received external radiation therapy eighteen years before, for endometrial carcinoma. We confirm that leiomyosarcoma may be a late uncommon effect of pelvic irradiation and suggest that close and long-term surveillance of irradiated patients is highly recommended.
authors.affiliation: Department of Surgery Pietro Valdoni, University La Sapienza, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Caporale
authors.forename: Francesco
authors.initials: F
authors.lastname: Angelico
authors.forename: Michele Umile
authors.initials: MU
authors.lastname: Cosenza
authors.forename: Andrea
authors.initials: A
authors.lastname: Giuliani
authors.forename: Maria
authors.initials: M
authors.lastname: Del Ben
authors.forename: Eugenio
authors.initials: E
authors.lastname: Benvenuto
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Franchi
mesh_terms: D000368:Aged; D001706:Biopsy; D003082:Colectomy; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D012007:Rectum / Q000473:pathology; D014057:Tomography, X-Ray Computed