Determinants of quality of life in first-episode psychosis.
OBJECTIVE
To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP).


METHODS
Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis.


RESULTS
Patients presented with varying levels of QOL on different domains. The level of 'general satisfaction' was related to age of onset and social premorbid adjustment; 'weighted index of QOL' to social premorbid adjustment and inversely to educational premorbid adjustment; 'social relations' inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; 'psychological well-being' inversely to depression and educational premorbid adjustment; 'activities of daily living' to social premorbid adjustment and inversely to negative symptoms; and 'outlook on symptoms' to level of depression.


CONCLUSIONS
Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.
Malla
A K
AK
McGill University, Montreal, Quebec, Canada. ashok.malla@douglas.mcgill.ca
Norman
R M G
RM
McLean
T S
TS
MacDonald
C
C
McIntosh
E
E
Dean-Lashley
F
F
Lynch
J
J
Scholten
D
D
Ahmed
R
R
D000328:Adult; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation; D011788:Quality of Life; D012044:Regression Analysis; D012917:Social Adjustment; D011795:Surveys and Questionnaires