Cutaneous lobular capillary hemangioma induced by pregnancy.
Lobular capillary hemangioma, which is also named as pyogenic granuloma, is a common vascular proliferation of skin and mucous membranes. Hormonal influence in the development of lobular capillary hemangioma on the mucosal surfaces has been demonstrated but for cutaneous lesions located on the skin, this association has not been shown yet. In this report, a 25-year-old female patient with cutaneous lobular capillary hemangioma of the cheek induced by pregnancy is presented. The lesion was excised and lobular capillary hemangioma was given as diagnosis by histopathological evaluation. Estrogen receptor was weakly positive by immunohistochemical analysis. We suggest that elevated levels of estrogens during pregnancy may have an important role also on the development of cutaneous lobular capillary hemangiomas by direct hormonal action.
Demir
Yavuz
Y
Department of Plastic Surgery, The Cleveland Clinic Foundation, Cleveland, OH, USA. demiry@ccf.org
Demir
Serap
S
Aktepe
Fatma
F
D000328:Adult; D002610:Cheek; D005260:Female; D017789:Granuloma, Pyogenic / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*; D011960:Receptors, Estrogen / Q000378:metabolism; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
D011960:Receptors, Estrogen