title: Measurement of central venous pressure from a peripheral vein in infants and children.
abstract: BACKGROUND
  Previous studies in adults have demonstrated a clinically useful correlation between central venous pressure (CVP) measured from a peripheral intravenous catheter and that measured from a central venous catheter. The current study prospectively compares CVP measurements from a central catheter and a peripheral catheter in infants and children.
  
  
  METHODS
  The study cohort included patients younger than 12 years presenting for a surgical procedure for which central venous access was necessary. CVP was measured simultaneously every 15 minutes for a total of 10 measurements from the central venous catheter and the peripheral IV catheter using standard pressure transducers, which were zeroed at the phlebostatic axis.
  
  
  RESULTS
  The cohort for the study included 30 infants and children ranging in age from 1 to 12 years. The peripheral IV catheter from which the CVP was measured ranged from a 24 to an 18 gauge. In 5 of the patients, there was no increase in the CVP value from the peripheral IV catheter in response to a sustained inspiratory breath or occlusion of the extremity above the catheter. In these 5 cases, the difference between the CVP measured from the central and peripheral catheter was 16 +/- 5 mm Hg versus 5 +/- 3 mm Hg in the other 25 patients (P < 0.0001). In the remaining 25 patients, the difference between the CVP measured from the peripheral and the central site was 5 +/- 3 mm Hg. There was no difference in the central versus peripheral CVP measurement depending on the size of the IV cannula, its location (upper versus lower extremity), or the patient's position.
  
  
  CONCLUSIONS
  CVP can be measured from a peripheral IV catheter in infants and children provided that there is continuity with the central venous compartment demonstrated by showing an increase in the CVP from the peripheral IV catheter in response to a sustained inspiratory effort and by occlusion of the extremity above the site of the catheter.
authors.affiliation: Department of Child Health, The University of Missouri, Columbia 65212, USA. Tobiasj@health.missouri.edu
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Tobias
authors.forename: Joel O
authors.initials: JO
authors.lastname: Johnson
mesh_terms: D001132:Arm; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods*; D002405:Catheterization, Central Venous; D002406:Catheterization, Peripheral; D002496:Central Venous Pressure; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003250:Constriction; D005260:Female; D006801:Humans; D007223:Infant; D001239:Inhalation; D007866:Leg; D008297:Male; D011446:Prospective Studies