[Changes of nitric oxide level at different stages of primary open-angle glaucoma].
The contents of NO stable metabolites in tears, and blood serum of the patients with different stages of open-angle glaucoma have been studied. The increasing of NO stable metabolite contents was found in tears, aqueous humor and blood serum during glaucoma progression. The depletion of glaucoma pathogenesis oxidative link was found at the terminal stage of the disease. The results of our investigation are proposed to be used for glaucoma diagnostic.
Gulaia
N M
NM
Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.
Zhaboedov
G D
GD
Petrenko
O V
OV
Kurilina
E I
EI
Kosiakova
G V
GV
Berdyshev
A G
AG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005902:Glaucoma, Open-Angle / Q000097:blood / Q000378:metabolism* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000032:analysis / Q000097:blood; D009569:Nitric Oxide / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D013666:Tears / Q000737:chemistry; D014787:Vision Tests
D009566:Nitrates; D009569:Nitric Oxide