title: Role functioning and symptom remission in women with postpartum depression after antidepressant treatment.
abstract: The primary purpose of this pilot study was to compare improvement of symptoms and role functioning in women with postpartum depression after 8 weeks of treatment with antidepressants. The study was a secondary data analysis from the preliminary data of a double blind, randomized clinical trial. The participants (n=61) were primarily Caucasian and slightly over half were married, first time mothers, and middle- to upper-middle-class. At intake, most participants were moderately to severely ill. At week one and week eight of the study, measures of symptoms and functioning were only moderately correlated. After 8 weeks of antidepressant treatment, symptoms and most measures of functional status improved; however, improvement in one dimension did not imply improvement in the other. Recommendations are given for clinical practice and further research in this area.
authors.affiliation: School of Nursing, University of Louisville, Louisville, KY, USA. mclogs@aol.com
authors.forename: M Cynthia
authors.initials: MC
authors.lastname: Logsdon
authors.forename: Katherine
authors.initials: K
authors.lastname: Wisner
authors.forename: Barbara H
authors.initials: BH
authors.lastname: Hanusa
authors.forename: Amanda
authors.initials: A
authors.lastname: Phillips
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D019052:Depression, Postpartum / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology*; D004311:Double-Blind Method; D005260:Female; D005783:Gender Identity; D006801:Humans; D008425:Maternal Behavior / Q000187:drug effects* / Q000523:psychology*; D009661:Nortriptyline / Q000627:therapeutic use; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D016032:Randomized Controlled Trials as Topic; D012074:Remission Induction; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D020280:Sertraline / Q000627:therapeutic use; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D009661:Nortriptyline; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline