title: [Electromagnetic noise blocks the gap-junctional intercellular communication suppression induced by 50 Hz magnetic field].
abstract: OBJECTIVE
  To explore whether the superposition of an electromagnetic noise can block gap-junctional intercellular communication(GJIC) suppression induced by 50 Hz 0.4 mT extremely low frequency magnetic field(ELF MF).
  
  
  METHODS
  Fibroblast cells of mice(NIH 3T3) were exposed to 0.4 mT ELF MF or(and) electromagnetic noise with the same intensity of MF for 24 h, and the GJIC was determined by using fluorescence recovery after photobleaching(FRAP) analysis, which was performed with a laser-scanning confocal microscope(Leica, Germany).
  
  
  RESULTS
  ELF MF exposure significantly inhibited GJIC with fluorescence recovery rate of 27.67% +/- 5.12% as compared with the control group(45.57% +/- 9.72%) (P < 0.01), while that of ELF MF plus noise group was (52.61% +/- 8.30%), which was significantly different from ELF MF group(P < 0.01), but not from control(P > 0.05).
  
  
  CONCLUSIONS
  Electromagnetic noise could block the GJIC suppression induced by 50 Hz 0.4 mT MF.
authors.affiliation: Bioelectromagnetic Lab., Zhejiang University School of Medicine, Hangzhou 310031, China.
authors.forename: Qunli
authors.initials: Q
authors.lastname: Zeng
authors.forename: Huai
authors.initials: H
authors.lastname: Chiang
authors.forename: Yiti
authors.initials: Y
authors.lastname: Fu
authors.forename: Deqiang
authors.initials: D
authors.lastname: Lu
authors.forename: Zhengping
authors.initials: Z
authors.lastname: Xu
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000528:radiation effects*; D004574:Electromagnetic Fields / Q000009:adverse effects*; D017629:Gap Junctions / Q000528:radiation effects*; D051379:Mice; D041681:NIH 3T3 Cells; D009622:Noise / Q000009:adverse effects*