[Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT)].
OBJECTIVE
To find out the relationship between the opacity in lens and the contents of 2,6-dinitro-4-amino-toluene(DNAT) in the urine of exposed workers.


METHODS
Testing the exposed worker's lens and measuring the contents of DNAT in the urine after work.


RESULTS
When the opacity of the lens occurred, the contents of DNAT in the urine(2.38 mg/L) of workers exposed to TNT were significantly higher than those without opacity in lens(1.44 mg/L) (P < 0.05).


CONCLUSIONS
The severity of opacity of lens increased with the contents of DNAT raised in the urine. The threshold value suggested by ILO is not applicable to Chinese occupational population, which recommends the contents of DNAT(30 mg/L) in the urine for the workers exposed to TNT as biological occupational exposed limits.
Zhu
Zhongde
Z
First Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000, China.
Li
Zhilan
Z
Mi
Fatai
F
Lian
Suqin
S
Dong
Pengcheng
P
Wu
Yuhua
Y
Sun
Xiaohua
X
D000814:Aniline Compounds / Q000652:urine*; D002386:Cataract / Q000139:chemically induced*; D004784:Environmental Monitoring; D006801:Humans; D016273:Occupational Exposure / Q000009:adverse effects*; D014303:Trinitrotoluene / Q000378:metabolism*
D000814:Aniline Compounds; D014303:Trinitrotoluene; C035207:4-amino-2,6-dinitrotoluene