HIV-1 seroprevalence rates in women and relinquishment of infants to the state in St Petersburg, Russia, 2002.
The effectiveness of rapid HIV-1 testing and nevirapine prophylaxis for HIV-infected mothers without prenatal care has been shown. We found that from 1998 to 2002, HIV-1 seroprevalence in women giving birth in St Petersburg, Russia increased 100-fold: from 0.013% to 1.3% (p<0.0001). HIV-1 seroprevalence was 8% (114 of 1466) in women without prenatal care and 1% (376 of 37645) in those with prenatal care (p<0.0001). All 376 HIV-1-infected women with, and 41% (47 of 114) of HIV-1-infected women without prenatal care received intrapartum antiretroviral therapy (p<0.0001). In women who were HIV-1 positive, 26% (30 of 114) of those without prenatal care and 4% (13 of 371) of those with prenatal care relinquished their infants to the custody of the state, compared with 1% (354 of 37 621) of HIV-1-negative women (p<0.0001).
Khaldeeva
N
N
St Petersburg Glaser Pediatric AIDS Foundation Planning Grant, St Petersburg, Russia. SEH0@cdc.gov
Hillis
S D
SD
Vinogradova
E
E
Voronin
E
E
Rakhmanova
A
A
Yakovlev
A
A
Jamieson
D J
DJ
Ryder
R W
RW
D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D002655:Child Custody / Q000706:statistics & numerical data*; D016241:Child of Impaired Parents / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission*; D006679:HIV Seropositivity / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission; D015528:HIV Seroprevalence / Q000639:trends; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D011159:Population Surveillance; D011247:Pregnancy; D011295:Prenatal Care; D012426:Russia / Q000453:epidemiology
D044966:Anti-Retroviral Agents