title: [The assessment of the influence of IgE-mediated food allergy on colonic transit time in children with chronic constipation].
abstract: The aim of the study was a comparative analysis of patients with chronic constipation and coexisting food allergy in relation to patients with functional chronic constipation without food allergy. 325 children with chronic constipation aged 0.6-17.1 years (mean 8.0 +/- 4.3) were included into the study. The IgE-mediated food allergy was diagnosed in 179 children. Results of anthropometric measurements, rectoscopies, abdominal ultrasonographies, evaluations of colonic transit time and anorectal manometric examinations, together with clinical symptoms, were analysed and compared. The results were subjected to statistical analysis. There were no significant differences in clinical presentation, anthropometric measurements, rectoscopic, ultrasonographic, manometric and histopathological findings between both groups. In the food allergy group the total and segmental colonic transit time more frequently was prolonged, manifested usually as colonic inertia (p < 0.001). Food allergy can be clinically manifested as a chronic constipation. IgE-mediated food allergy may significantly prolong colonic transit in affected patients.
authors.affiliation: Oddział Dzieciecy Szpitala Wojewódzkiego Nr 2 w Rzeszowie.
authors.forename: Wrzesław
authors.initials: W
authors.lastname: Romańczuk
authors.forename: Antoni
authors.initials: A
authors.lastname: Samojedny
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003106:Colon / Q000503:physiopathology*; D003248:Constipation / Q000503:physiopathology*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007223:Infant; D008297:Male
chemical_list: D007073:Immunoglobulin E