A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway.
A wing specific F1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.
Lin
Xin-da
XD
Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China. linxinda@yahoo.com
Lin
Xin-hua
XH
Chen
Jia-an
JA
D000818:Animals; D002874:Chromosome Mapping / Q000379:methods*; D004252:DNA Mutational Analysis / Q000379:methods*; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D004331:Drosophila melanogaster / Q000166:cytology / Q000235:genetics* / Q000254:growth & development* / Q000378:metabolism; D005820:Genetic Testing / Q000379:methods*; D016297:Mutagenesis, Site-Directed; D010641:Phenotype; D015398:Signal Transduction / Q000235:genetics*; D014921:Wings, Animal / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism
D029721:Drosophila Proteins; C456459:Notum protein, Drosophila