[Bile duct obstruction due to non-Hodkin's lymphoma in patients with HIV infection].
Acquired immune deficiency syndrome increases the risk of developing non-Hodgkin's B-cell lymphoma (NHL) (relative risk over 100). NHL tend to be high-grade and to affect the central nervous system and digestive tract. Biliary tract compression is usually due to external compression from enlarged lymph nodes, but is not usually the first manifestation.We describe 2 cases of bile duct obstruction secondary to NHL in patients diagnosed with HIV infection. Histological diagnosis of the lymphoma can be difficult but is necessary so that these patients do not undergo highly aggressive surgical treatment instead of chemotherapy, which currently produces the best results. Therefore, we emphasize the importance of including lymphomas in the differential diagnosis of bile duct obstruction in patients with HIV infection.
Gómez-Domínguez
E
E
Servicio de Aparato Digestivo. Hospital Universitario de La Princesa. Madrid. Spain. elenagodo@yahoo.es
Rodríguez Serrano
D A
DA
Mendoza
J
J
Iscar
T
T
Sarriá
C
C
García-Buey
L
L
D001853:Bone Marrow / Q000473:pathology; D002779:Cholestasis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D004322:Drainage / Q000379:methods; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed