[Brugada syndrome].
The Brugada syndrome is a clinical-electrocardiographic diagnosis characterized by syncopal episodes or sudden death (caused by ventricular tachycardia and ventricular fibrillation) in patients with a structurally normal heart with a characteristic electrocardiographic pattern consisting of ST segment elevation in precordial leads (Vl-V3) and a morphology of the QRS complex resembling right bundle branch block (the latter can transiently disappear). Timely diagnosis and adequate treatment may essentially decrease mortality of this disease. In our review we have summarized results of recent studies of etiology, pathogenesis, clinical picture, diagnosis and treatment of the Brugada syndrome.
Vatutin
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NT
Donetsk State Medical University, Institute for Citical Surgery, Ukraine.
Skliannaia
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D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D006801:Humans; D011379:Prognosis; D013575:Syncope / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D013577:Syndrome