Body cell mass measured by total body potassium in normal-weight and obese men and women.
OBJECTIVE
Total body potassium (TBK) concentration is linearly correlated with the size of the body cell mass (BCM). The aim of this study was to compare BCM in normal-weight and obese individuals.


METHODS
271 individuals (207 males, 64 females), 20 to 67 years of age, participated in this study. Subjects were separated by body mass index (BMI): BMI < 25 kg/m(2) (BMI-L) and BMI > 25 kg/m(2) (BMI-H). (40)K was assessed using a whole-body counter and BCM was calculated.


RESULTS
BCM and TBK were significantly greater in men, with a trend to be greater in women in BMI-H compared to men in BMI-L. TBK/body weight was significantly lower, while TBK/height was significantly greater for men and women in BMI-H compared to men and women in BMI-L. Fat-free mass (FFM) was significantly greater for men in BMI-H, with no significant differences in FFM between the two groups of women.


CONCLUSIONS
The healthy obese subjects in the present study had a greater BCM than the non-obese subjects. These results indicate that it is important to assess BCM in obese individuals because it could influence the type of weight loss regimen that will be used in order to preserve BCM.
De Lorenzo
Antonino
A
Human Nutrition Unit, Via Montpellier 1, University of Rome Tor Vergata, 00173 Rome, Italy.
Andreoli
Angela
A
Serrano
Paola
P
D'Orazio
Nicolantonio
N
Cervelli
Valerio
V
Volpe
Stella L
SL
D000273:Adipose Tissue / Q000378:metabolism; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000032:analysis; D001823:Body Composition; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000166:cytology* / Q000378:metabolism; D009765:Obesity / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D011197:Potassium Radioisotopes; D012737:Sex Factors; D014915:Whole-Body Counting
D015415:Biomarkers; D011197:Potassium Radioisotopes; D011188:Potassium