[Evaluation of serum sICAM-1 and sVCAM-1 concentration in patient at risk of preterm delivery].
Aim of the study was to assess the serum adhesion molecules concentration in patients at risk of preterm labour. Sixty-three patients were divided into two groups basing on cervical evaluation (Bishop's score > or = 6 and < 6). The assessment of sICAM-1 and sVCAM-1 levels in serum were carried out by immunoenzymatic ELISA test utilizing monoclonal antibodies (moAb) against human sICAM-1 and sVCAM-1 (ELISA system, R&Q, USA). Among the patients at risk of preterm labour and Bishop's score > or = 6 statistically higher serum levels of sICAM-1 were found. There were no statistically significant differences in sVCAM-1 levels between examined groups. We conclude that serum sICAM-1 determination might improve the prediction of preterm birth.
Urban
Remigiusz
R
Kliniki Perinatologii i Połoznictwa AM w Białymstoku.
Lemancewicz
Adam
A
Urban
Jan
J
Kretowska
Małgorzata
M
D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D007752:Obstetric Labor, Premature / Q000276:immunology* / Q000517:prevention & control; D011044:Poland; D011237:Predictive Value of Tests; D011247:Pregnancy; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013997:Time Factors; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood*
D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1