title: Experience with the use of tissue adhesives in pediatric endoscopic surgery.
abstract: BACKGROUND
  Due to technological improvements, the use of tissue adhesives and glues for tissue approximation and hemostasis in surgery has increased. We report our preliminary experience with this technology in pediatric endosurgery.
  
  
  METHODS
  Between 1997 and 2000, we employed tissue adhesives in 48 pediatric patients during laparoscopic procedures. In 25 patients, the glue was adopted for the hemostasis of parenchimal organs (liver in 24 cases and spleen in one). In three cases, the glue was used to repair organ perforation, in 19 it was used to close the distal part of a patent processus vaginalis in case of congenital inguinal hernia. In the final case, the glue was adopted to achieve optimal airtightness in case of pulmonary biopsy. The glue was injected with the aid of a needle positioned transparietally.
  
  
  RESULTS
  The procedure was easy and rapid in all cases, and there were no problems or complications related to glue positioning at a mean follow up of 51 months.
  
  
  CONCLUSIONS
  Tissue adhesives are a very versatile product for use in pediatric laparoscopic surgery. It is likely that their usage will increase as the technology improves and more effective products are developed.
authors.affiliation: Department of Experimental and Clinical Medicine, Chair of Pediatric Surgery, "Magna Graecia" University, Via Tommaso Campanella 115, 88100, Catanzaro, Italy. ciroesp2@unicz.it
authors.forename: C
authors.initials: C
authors.lastname: Esposito
authors.forename: R
authors.initials: R
authors.lastname: Damiano
authors.forename: A
authors.initials: A
authors.lastname: Settimi
authors.forename: M
authors.initials: M
authors.lastname: De Marco
authors.forename: P
authors.initials: P
authors.lastname: Maglio
authors.forename: A
authors.initials: A
authors.lastname: Centonze
mesh_terms: D001706:Biopsy; D002648:Child; D003487:Cyanoacrylates / Q000627:therapeutic use*; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology / Q000628:therapy; D007431:Intraoperative Complications / Q000628:therapy; D010535:Laparoscopy / Q000706:statistics & numerical data; D008297:Male; D011183:Postoperative Complications / Q000628:therapy; D012189:Retrospective Studies; D013906:Thoracoscopy / Q000706:statistics & numerical data; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C421460:glubran