title: WormBase: a multi-species resource for nematode biology and genomics.
abstract: WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with extensively annotated views of the genome. The WormBase Consortium continues to expand the biological scope and utility of WormBase with the inclusion of large-scale genomic analyses, through active data and literature curation, through new analysis and visualization tools, and through refinement of the user interface. Over the past year, the nearly complete genomic sequence and comparative analyses of the closely related species Caenorhabditis briggsae have been integrated into WormBase, including gene predictions, ortholog assignments and a new synteny viewer to display the relationships between the two species. Extensive site-wide refinement of the user interface now provides quick access to the most frequently accessed resources and a consistent browsing experience across the site. Unified single-page views now provide complete summaries of commonly accessed entries like genes. These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system.
authors.affiliation: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. harris@cshl.org
authors.forename: Todd W
authors.initials: TW
authors.lastname: Harris
authors.forename: Nansheng
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authors.lastname: Chen
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authors.lastname: Tello-Ruiz
authors.forename: Igor
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authors.lastname: Antoshechkin
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authors.forename: Tamberlyn
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authors.lastname: Bieri
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authors.forename: Juancarlos
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authors.lastname: Chan
authors.forename: Chao-Kung
authors.initials: CK
authors.lastname: Chen
authors.forename: Wen J
authors.initials: WJ
authors.lastname: Chen
authors.forename: Paul
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authors.lastname: Davis
authors.forename: Eimear
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authors.lastname: Kenny
authors.forename: Ranjana
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authors.lastname: Kishore
authors.forename: Daniel
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authors.lastname: Lawson
authors.forename: Raymond
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authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Muller
authors.forename: Cecilia
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authors.lastname: Nakamura
authors.forename: Philip
authors.initials: P
authors.lastname: Ozersky
authors.forename: Andrei
authors.initials: A
authors.lastname: Petcherski
authors.forename: Anthony
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authors.lastname: Rogers
authors.forename: Aniko
authors.initials: A
authors.lastname: Sabo
authors.forename: Erich M
authors.initials: EM
authors.lastname: Schwarz
authors.forename: Kimberly
authors.initials: K
authors.lastname: Van Auken
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Wang
authors.forename: Richard
authors.initials: R
authors.lastname: Durbin
authors.forename: John
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authors.lastname: Spieth
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authors.forename: Lincoln D
authors.initials: LD
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mesh_terms: D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000235:genetics*; D019295:Computational Biology; D030541:Databases, Genetic; D023281:Genomics; D016247:Information Storage and Retrieval; D020407:Internet; D014584:User-Computer Interface