title: Primary orbital plasmacytoma: A case report.
abstract: A 50-year-old man presented with a fungating growth in the left eye of 3 months duration. Biopsy of the mass followed by light microscopy was suggestive of plasmacytoma and the diagnosis was confirmed by immunohistochemical stains, which demonstrated monoclonality to kappa light chains. Systemic investigations ruled out a multiple myeloma. The patient received radiotherapy; however, due to a residual mass, the left orbit had to be exenterated. Solitary plasmacytomas may not always be completely radiosensitive and radical surgery may be required in such cases. Immunohistochemical stains for kappa and lambda light chains can prove useful in confirming the diagnosis of suspected plasmacytomas.
authors.affiliation: Department of Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. ssenop@rediffmail.com
authors.forename: Seema
authors.initials: S
authors.lastname: Sen
authors.forename: Seema
authors.initials: S
authors.lastname: Kashyap
authors.forename: Subhash
authors.initials: S
authors.lastname: Betharia
mesh_terms: D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D010954:Plasmacytoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery