title: Transcatheter occlusion of moderate to large patent arterial ducts, having a diameter above 2.5 mm, with the Amplatzer Duct Occluder. Comparisons with the Rashkind, buttoned devices, and coils in 116 consecutive patients.
abstract: OBJECTIVE
  To report results of transcatheter occlusion of moderate to large patent arterial ducts, having a minimum diameter above 2.5 mm, with the Amplatzer duct occluder, and to compare these with results achieved using Rashkind or Sideris devices and Cook detachable coils.
  
  
  METHODS
  Retrospective study conducted on intention-to-treat data from a tertiary referral centre.
  
  
  METHODS
  Since 1989, 116 consecutive patients, 77 females and 39 males, underwent percutaneous closure with several devices. We used the Rashkind double umbrella in 23 patients, the Sideris buttoned device in 39 patients, coils in 17 patients, and the Amplatzer duct occluder in 37 patients. The median age of the patients was 37 months, and the median weight 13 kg. The mean minimum diameter of the duct was 3.8 +/- 1.22 mm, with a median of 3.5 mm, and range from 2.5 to 10 mm.
  
  
  RESULTS
  Implantation succeeded in all but 9 of the children (92%). The time of fluoroscopy was shorter, and full occlusion was better as judged on angiography, in patients closed using the Amplatzer device, despite closure of larger ducts, than in patients closed using other devices (p < 0.0001, p = 0.0003, and p = 0.0015 for the Rashkind, Sideris, and coils, respectively). Complications included embolisation in 2 patients, and haemolysis in 3 patients. In 12 patients, a second device was inserted because of residual shunting noted during follow-up. Complete occlusion was achieved earlier after implantation (p = 0.0002), and the rate of complete occlusion was better in patients receiving an Amplatzer device (97%, p = 0.024) than in patients undergoing closure with other devices.
  
  
  CONCLUSIONS
  Transcatheter closure of moderate to large patent arterial ducts using the Amplatzer duct occluder is an effective and safe procedure, providing better results than those achieved using other occluders.
authors.affiliation: Department of Paediatric Cardiology, Cardiac Hospital, Lille, France. f-godart@chru-lille.fr
authors.forename: François
authors.initials: F
authors.lastname: Godart
authors.forename: Christian
authors.initials: C
authors.lastname: Rey
authors.forename: Patrick
authors.initials: P
authors.lastname: Devos
authors.forename: Georges-Marie
authors.initials: GM
authors.lastname: Brevière
authors.forename: Charles
authors.initials: C
authors.lastname: Francart
mesh_terms: D002404:Catheterization; D002675:Child, Preschool; D004617:Embolism / Q000209:etiology; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014656:Vascular Surgical Procedures / Q000295:instrumentation / Q000379:methods*