title: Functional MRI and Wada determination of language lateralization: a case of crossed dominance.
abstract: The Wada test has historically been the conventional procedure for determining language lateralization before neurosurgery. However, functional magnetic resonance imaging (fMRI) offers a less invasive alternative to the Wada procedure. Research indicates that the two techniques used together may provide comparable, and sometimes complementary, information that results in improved prediction of postsurgical language ability. We present a case in which use of fMRI in conjunction with Wada testing provided complementary information about language lateralization before neurosurgical resection of a mesial temporal subependymoma for seizure control in a patient with schizencephaly.
authors.affiliation: St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
authors.forename: Michele L
authors.initials: ML
authors.lastname: Ries
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Boop
authors.forename: May L
authors.initials: ML
authors.lastname: Griebel
authors.forename: Ping
authors.initials: P
authors.lastname: Zou
authors.forename: Nicholas S
authors.initials: NS
authors.lastname: Phillips
authors.forename: Sterling C
authors.initials: SC
authors.lastname: Johnson
authors.forename: Jane P
authors.initials: JP
authors.lastname: Williams
authors.forename: Kathleen J
authors.initials: KJ
authors.lastname: Helton
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Ogg
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology; D002648:Child; D004833:Epilepsy, Temporal Lobe / Q000473:pathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011300:Preoperative Care / Q000379:methods; D013060:Speech / Q000502:physiology*