title: The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin.
abstract: Advances over the past decade suggest a need to reassess the distribution of ovarian surface epithelial tumors. A series of 220 consecutive invasive ovarian carcinomas, including carcinosarcomas and peritoneal carcinomas, was reviewed. Notable findings include: 7% of tumors were carcinosarcomas; 22% of cases of peritoneal serous carcinomatosis were of peritoneal origin; <3% of cases were mucinous carcinomas; and only one malignant Brenner tumor (0.5%) and no pure transitional cell carcinomas were identified. If peritoneal carcinomas, carcinosarcomas, and mixed carcinomas with a serous component are combined with serous carcinomas, this group accounts for 78% of all cases and 87% of advanced stage cases, suggesting a greater uniformity to epithelial ovarian cancer than previously appreciated.
authors.affiliation: Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA. Jeffrey.D.Seidman@medstar.net
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Seidman
authors.forename: Iren
authors.initials: I
authors.lastname: Horkayne-Szakaly
authors.forename: Moutaz
authors.initials: M
authors.lastname: Haiba
authors.forename: Charles R
authors.initials: CR
authors.lastname: Boice
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Kurman
authors.forename: Brigitte M
authors.initials: BM
authors.lastname: Ronnett
mesh_terms: D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology*; D012189:Retrospective Studies