[Intravascular lymphoma of the central nervous system].
Intravascular lymphomatosis is an uncommon lymphoproliferative disorder characterised by intravascular distribution of neoplastic lymphoid cells (B- or T-lymphocites), what leads to occlusion of small vessels and causes signs and symptoms of disorder. Its initial predilection sites are the brain or the skin, and hematopoetic organs are usually spared. The signs and symptoms of the disorder are attributed to vascular occlusion. Clinical course is fatal, besides therapy. In our case disorder has started with partial epileptic seizures with secundar generalisation, and after that with motor aphasia, right hemiparesis, urinary incontinence and cognitive changes. She was hospitalized for several times, completely investigated, but with no conclusion. Seven months after apperance of symptoms, she died. And diagnosis was determined at autopsy. A myriad of neurological and systemic manifestations are putting us in an unequal position with this fatal disease. Early diagnosis can increase survival and decrease intensity of symptoms. So every new case is important as warning that we must not forget about this disease.
Jović
Jasmina
J
Health Centre Dr Radivoj Simonovic Sombor.
Ercegovac
Marko
M
Dozić
Branko
B
Cvetković
Dubravka
D
Zivković
Miroslava
M
Beslać-Bumbaserević
Ljiljana
L
D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged