Memory, synaptic translation, and...prions?
Two papers from Kausik Si, Eric Kandel, Susan Lindquist, and colleagues set forth a bold new idea for thinking about the mechanisms underlying the generation and maintenance of long-term memories (Si et al., 2003a, 2003b [this issue of Cell]).
Darnell
Robert B
RB
Howard Hughes Medical Institute, Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, NY 10021, USA.
D000818:Animals; D006801:Humans; D008568:Memory / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D011328:Prions / Q000502:physiology*; D014176:Protein Biosynthesis / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D029867:Xenopus Proteins / Q000235:genetics / Q000378:metabolism; D039221:mRNA Cleavage and Polyadenylation Factors
C490388:Cpeb1 protein, Xenopus; D011328:Prions; D014157:Transcription Factors; D029867:Xenopus Proteins; D039221:mRNA Cleavage and Polyadenylation Factors