title: Synovial sarcoma: a rare tumor of larynx.
abstract: Synovial sarcoma is a soft tissue sarcoma of unknown histogenesis and occurs predominantly in the lower extremities of young adults. The head and neck is a relative rare location. There are about 10 cases with laryngeal localization in the literature. We present a 24 year-old male with an endolaryngeal mass. Incisional biopsy and the hemilaryngectomy material revealed a biphasic synovial sarcoma. One year later a local recurrence occurred. Tumor excision and neck dissection were performed. Radiotherapy was added. Six months later lung metastases was discovered on thoracic CT. The patient received chemotherapy for 6 courses. The metastases responded well to chemotherapy and the patient is now alive without tumor on radiological and clinical examination after 3.5 years of follow-up.
authors.affiliation: Department of Pathology, Istanbul Medical Faculty, 34390 Istanbul, Turkey. eminbilgic@superonline.com
authors.forename: Bilge
authors.initials: B
authors.lastname: Bilgic
authors.forename: Ozgür
authors.initials: O
authors.lastname: Mete
authors.forename: Settar A
authors.initials: SA
authors.lastname: Oztürk
authors.forename: Misten
authors.initials: M
authors.lastname: Demiryont
authors.forename: Nesil
authors.initials: N
authors.lastname: Keles
authors.forename: Mert
authors.initials: M
authors.lastname: Basaran
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D007825:Laryngectomy; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy; D011878:Radiotherapy; D013584:Sarcoma, Synovial / Q000556:secondary* / Q000628:therapy