title: Changes of fascia and muscles before and 12 months after successful treatment of recalcitrant venous leg ulcers by shave therapy.
abstract: BACKGROUND
  In chronic venous insufficiency (CVI) III typical changes of skin, subcutaneous tissue, fascia and muscle can be found. It was believed, that the thickening of the fascia is irreversible and it has been postulated that the degeneration of muscles is causative for the persistence of recalcitrant leg ulcers.
  
  
  METHODS
  By computed tomography (CT) and magnetic resonance imaging (MRI) 8 patients with therapy resistant venous ulcers were examined. Changes of fascia and muscles were determined preoperatively and 12 months after successful shave therapy.
  
  
  RESULTS
  By CT a thinning of the preoperatively thickened fascia could be demonstrated in all patients one year after surgery. Before shave therapy MRI showed that the fascia was not only thickened and blurred, but also had fluid accumulations perifascial. 12 months after therapy the fascia was thinner and sharply demarcated. The fluid was either absent or distinctively reduced. Referring to the thickness of fascia an average decrease of 0.084 cm (0.03-0.17 cm) was observed. Before surgery the muscles showed a fatty degeneration as a sign of atrophy; with CT and MRI no changes could be demonstrated after one year in all patients.
  
  
  CONCLUSIONS
  The results after one year demonstrate for the first time, that the changes of the fascia in CVI III are reversible and that there is no direct correlation between the degeneration of muscles and the persistence of venous leg ulcers.
authors.affiliation: Department of Dermatology and Venerology, Medical University of Lübeck, Germany. Yvonne.Gaber@medinf.mu-luebeck.de
authors.forename: Y
authors.initials: Y
authors.lastname: Gaber
authors.forename: H B
authors.initials: HB
authors.lastname: Gehl
authors.forename: W
authors.initials: W
authors.lastname: Schmeller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003646:Debridement; D005205:Fascia / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008068:Lipomatosis / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D011183:Postoperative Complications / Q000473:pathology*; D012008:Recurrence; D012594:Scleroderma, Localized / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation; D014057:Tomography, X-Ray Computed; D014647:Varicose Ulcer / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology