title: A semi-automatic method for left ventricle volume estimate: an in vivo validation study.
abstract: This study aims to the validation of the left ventricular (LV) volume estimates obtained by processing volumetric data utilizing a segmentation model based on level set technique. The validation has been performed by comparing real-time volumetric echo data (RT3DE) and magnetic resonance (MRI) data. A validation protocol has been defined. The validation protocol was applied to twenty-four estimates (range 61-467 ml) obtained from normal and pathologic subjects, which underwent both RT3DE and MRI. A statistical analysis was performed on each estimate and on clinical parameters as stroke volume (SV) and ejection fraction (EF). Assuming MRI estimates (x) as a reference, an excellent correlation was found with volume measured by utilizing the segmentation procedure (y) (y=0.89x + 13.78, r=0.98). The mean error on SV was 8 ml and the mean error on EF was 2%. This study demonstrated that the segmentation technique is reliably applicable on human hearts in clinical practice.
authors.affiliation: DEIS, University of Bologna, Bologna, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Corsi
authors.forename: C
authors.initials: C
authors.lastname: Lamberti
authors.forename: A
authors.initials: A
authors.lastname: Sarti
authors.forename: G
authors.initials: G
authors.lastname: Saracino
authors.forename: T
authors.initials: T
authors.lastname: Shiota
authors.forename: J D
authors.initials: JD
authors.lastname: Thomas
mesh_terms: D019560:Echocardiography, Three-Dimensional / Q000379:methods* / Q000706:statistics & numerical data; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D012044:Regression Analysis; D015203:Reproducibility of Results; D013318:Stroke Volume / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*