title: [Congenital rubella syndrome and the occurrence of congenital heart disease].
abstract: Aiming to document the incidence and type of associated congenital heart disease, 20 children affected with the congenital rubella syndrome have been evaluated during a 5 year period, starting 1988. Congenital heart disease was detected in 45% of the cases. Persistent ductus arteriosus was the most frequent finding, followed by ventricular and atrial septal defects. Hearing disturbances occurred in 83% of the 12 cases studied. Ophthalmic lesions appeared in 69% of the 13 cases analysed, congenital cataracts being the most frequent one. An association of 66% was found between ophthalmic and heart lesions. Regarding the nutritional index, 70% of the cases were situated between the 25th and 50th percentile. The relevant incidence of congenital defects and the documentation of an important number of cases in a short period of time point out to a significant prevalence of the syndrome with imperative need improve the vaccination programs.
authors.affiliation: Depto de Puericultura e Pediatria, Faculdade de Medicina de Ribeirão Preto-USP, Ribeirão Preto, SP.
authors.forename: J A
authors.initials: JA
authors.lastname: Granzotti
authors.forename: F T
authors.initials: FT
authors.lastname: Amaral
authors.forename: C A
authors.initials: CA
authors.lastname: Sassamoto
authors.forename: M A
authors.initials: MA
authors.lastname: Nunes
authors.forename: M A
authors.initials: MA
authors.lastname: Grellet