Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome.
In patients with troponin-negative acute coronary syndromes, creatine kinase (CK)-MB elevation predicts a significantly higher risk of death and major acute cardiac events compared with CK-MB negative patients. This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonstrate ST elevation by electrocardiogram.
Yee
Kimberly C
KC
Division of Cardiology, Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor, Michigan, USA.
Mukherjee
Debabrata
D
Smith
Dean E
DE
Kline-Rogers
Eva M
EM
Fang
Jianming
J
Mehta
Rajendra H
RH
Almanaseer
Yassar
Y
Akhras
Eyad
E
Cooper
Jeanna V
JV
Eagle
Kim A
KA
D000208:Acute Disease; D000368:Aged; D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000150:complications / Q000401:mortality; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010359:Patient Readmission / Q000706:statistics & numerical data; D011237:Predictive Value of Tests; D011379:Prognosis; D013577:Syndrome; D019210:Troponin I / Q000097:blood*
D015415:Biomarkers; D007527:Isoenzymes; D019210:Troponin I; D003402:Creatine Kinase