title: Radius of curvature and asphericity of the anterior and posterior surface of human cadaver crystalline lenses.
abstract: The purpose of this study was to measure the shape of the anterior and posterior surface of human cadaver lenses in situ using a corneal topography system. Measurements were performed on 13 pairs of eyes using the PAR Corneal Topography System (PAR-CTS). The age of the donors ranged from 46 to 93 years, with an average age of 76.4 years. Anterior lens topography was measured after excision of the cornea and iris. Posterior lens topography was measured after sectioning the posterior segment and adherent vitreous. The PAR-CTS files providing raw surface height were exported for analysis. In each surface, 18 meridians separated by 10 degrees were fitted using conic sections to obtain values of the apical radius of curvature (R) and shape factor (p). The average apical radius of curvature and asphericity were R=10.15+/-1.39mm and p=4.27+/-1.39 for the anterior surface and R=-6.25+/-0.79mm and p=-0.64+/-1.85 for the posterior surface. A significant variation of the radius of curvature and shape factor as a function of the meridian angle (lens astigmatism) was found in some lenses. Contrary to previous findings, the anterior lens surface was found to steepen toward the periphery.
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami School of Medicine, 1638 NW 10th Avenue, Miami, FL 33136, USA. fmans@miami.edu
authors.forename: Fabrice
authors.initials: F
authors.lastname: Manns
authors.forename: Viviana
authors.initials: V
authors.lastname: Fernandez
authors.forename: Stanley
authors.initials: S
authors.lastname: Zipper
authors.forename: Samith
authors.initials: S
authors.lastname: Sandadi
authors.forename: Marie
authors.initials: M
authors.lastname: Hamaoui
authors.forename: Arthur
authors.initials: A
authors.lastname: Ho
authors.forename: Jean Marie
authors.initials: JM
authors.lastname: Parel
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001251:Astigmatism / Q000473:pathology; D019781:Corneal Topography / Q000379:methods; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology* / Q000473:pathology; D008875:Middle Aged; D012016:Reference Values; D013048:Specimen Handling / Q000379:methods