title: Meta-analysis of randomized clinical trials on the usefulness of acetylcysteine for prevention of contrast nephropathy.
abstract: Multiple small studies of oral N-acetylcysteine for prevention of contrast nephropathy have been performed, demonstrating variable efficacy. We performed a meta-analysis of the randomized clinical trials to clarify the degree of benefit.
authors.affiliation: Cardiovascular Service, Walter Reed Army Medical Center, Washington, DC, USA. daniel.isenbarger@na.amedd.army.mil
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Isenbarger
authors.forename: Steven M
authors.initials: SM
authors.lastname: Kent
authors.forename: Patrick G
authors.initials: PG
authors.lastname: O'Malley
mesh_terms: D000111:Acetylcysteine / Q000627:therapeutic use*; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000517:prevention & control*; D000975:Antioxidants / Q000627:therapeutic use*; D003287:Contrast Media / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood; D006801:Humans; D016032:Randomized Controlled Trials as Topic
chemical_list: D000975:Antioxidants; D003287:Contrast Media; D003404:Creatinine; D000111:Acetylcysteine