title: By the way, doctor. I've been on warfarin (Coumadin) since 1979 after having a Starr-Edwards valve put in. The cardiologist insists on aggressive therapy and wants my INR at 3.5. But I've had several serious bleeds in the past year and was hospitalized three times. What's the current thinking about adequate INR levels for patients with metal heart valves?
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Lee
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects; D006350:Heart Valve Prosthesis; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D019934:International Normalized Ratio / Q000592:standards*; D012016:Reference Values; D013997:Time Factors; D014859:Warfarin / Q000009:adverse effects
chemical_list: D000925:Anticoagulants; D014859:Warfarin