[Some clinical aspects of hepatitis A during the epidemiologic increase of morbidity in Gdansk Providence in the years 1991-1993].
OBJECTIVE
Clinical analysis of hepatitis A cases among patients hospitalized during the last increase of morbidity, in years 1991-1993, in Gdańsk province.


METHODS
Retrospective examination of 3040 cases of hepatitis A from the departments of infectious diseases in Gdańsk that was executed basing on medical documents.


RESULTS
There were no significant differences in number of patients according to sex (51.8%--men), persons in age 11-20 yrs were in the majority (39.8%), 91% of patients were younger than 30 yrs. The time of treatment was not equal, it usually fluctuated from 2 to 4 weeks (92% of cases). Groups of men became more numerous in comparison to women parallel with prolongation of hospitalization time. Patients older than 20 yrs were more often observed and cured at the hospital than younger ones. Mild clinical course was observed in 1464, moderate in 1548, severe in 26 and fulminant in 2 cases. In some cases there were noted symptoms of malfunction of other organs as skin, joints, respiratory, cardiovascular, digestive systems. 417 patients demonstrated serological markers of persistent or past HBV infection.


CONCLUSIONS
1. The course of initial disease was similar as in other papers. 2. More than 90% of patients were treated no longer than 6 weeks. Together with prolongation of hospitalization time groups of men and older patients became more numerous. 3. Mild and moderate cases dominated in clinical analysis, two deaths were noted. 4. Malfunction of other organs was observed in nearly of 30% of patients.
Sikorska
Katarzyna
K
Klinika Chorób Zakaźnych Akademii Medycznej w Gdańsku.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006506:Hepatitis A / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D035922:Hepatitis A Antibodies / Q000097:blood; D017957:Hepatitis A Virus, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors
D035922:Hepatitis A Antibodies