[The impact of night work near the day of ovulation on outcome of pregnancy].
OBJECTIVE
To investigate the effect of night work near the day of ovulation on outcome of pregnancy.


METHODS
Daily early morning urine samples were collected from eligible shift women workers, and human chorionic gonadotropin(hCG), follicle-stimulating hormone(FSH), the urinary steroid metabolites of estrogen and progesterone(PDG, E1C) were measured to confirm the day of ovulation and early fetal loss(EFL). Questionnaires were used to know workshift, other occupation exposures, and related information.


RESULTS
12 clinical spontaneous abortion(SAB), 18(EFL) and 44 clinical living birth were analyzed in relation to SAB, EFL and night shift near the day of ovulation by using single factor and multi-factor logistic regression. The result showed that night shift on the day of ovulation and the day before or after ovulation was related with SAB both in single- and muti-factorial analysis(single factor: OR = 2.48, 95% CI 1.10-5.60; multi-factor; OR = 3.90, 95% CI 1.28-11.90).


CONCLUSIONS
Night shift near the day of ovulation may be related to SAB.
Li
Peizhi
P
Department of Occupational and Environmental Health, Public Health College, Peking University, Beijing 100083, China.
Fang
Ziguo
Z
Pan
Xiaochuan
X
Wang
Lihua
L
Xu
Xiping
X
D000022:Abortion, Spontaneous / Q000209:etiology*; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D016015:Logistic Models; D010060:Ovulation; D011247:Pregnancy; D014940:Work Schedule Tolerance
D006063:Chorionic Gonadotropin; D005640:Follicle Stimulating Hormone