title: The solid-phase conjugation of purpurin-18 with a synthetic targeting peptide.
abstract: It has been demonstrated that efficient site-specific coupling of the highly active photodynamic therapy sensitiser purpurin-18 to the synthetic targeting peptide G-G-V-K-R-K-K-K-P-G-Y-G can be achieved with greater than 85% purity.
authors.affiliation: Centre for Photobiology and Photodynamic Therapy, Department of Biochemistry and Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Walker
authors.forename: David I
authors.initials: DI
authors.lastname: Vernon
authors.forename: Stanley B
authors.initials: SB
authors.lastname: Brown
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D009842:Oligopeptides / Q000032:analysis / Q000737:chemistry*; D017319:Photosensitizing Agents / Q000032:analysis / Q000737:chemistry*; D011166:Porphyrins / Q000032:analysis / Q000737:chemistry*
chemical_list: D009842:Oligopeptides; D017319:Photosensitizing Agents; D011166:Porphyrins; C059051:purpurin 18