title: Paratesticular congenital malignant rhabdoid tumor diagnosed by fine-needle aspiration cytology. a case report.
abstract: We report the FNA features of a congenital malignant extrarenal rhabdoid tumor (MERT) located in the right paratesticular area of a newborn full-term boy (39 wk gestation), with disseminated metastases in the liver and right parietal region. The diagnosis was suggested two days after birth by fine-needle aspiration biopsy (FNAB) of the parietal mass, which demonstrated an atypical large cell proliferation with vesicular nuclei, prominent nucleoli, and abundant cytoplasm exhibiting paranuclear dense inclusions. The diagnosis was confirmed by histopathologic and immunohistochemical examination of the primary paratesticular tumor. To the best of our knowledge, this is the third MERT reported in the paratesticular region, one of the few congenital extrarenal non-central nervous system cases, and the third congenital case (renal or extrarenal) primarily diagnosed by FNAB. We emphasize the characteristic cytologic features of a congenital rhabdoid tumor, which must be known by pathologists because of the clinical and prognostic implications. Diagn. Cytopathol. 2004;30:46-50.
authors.affiliation: Department of Pathology, "12 de Octubre" University Hospital, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Salamanca
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rodríguez-Peralto
authors.forename: Daniel
authors.initials: D
authors.lastname: Azorín
authors.forename: Claudio
authors.initials: C
authors.lastname: Ballestín
authors.forename: Pedro
authors.initials: P
authors.lastname: De Agustín
mesh_terms: D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D018335:Rhabdoid Tumor / Q000151:congenital* / Q000473:pathology*; D012208:Rhabdomyosarcoma / Q000235:genetics / Q000473:pathology; D013736:Testicular Neoplasms / Q000151:congenital* / Q000473:pathology*