title: Subclinical vestibulocerebellar dysfunction in migraine with and without aura.
abstract: OBJECTIVE
  In patients with migraine, neurotologic symptoms and signs occur commonly. The authors' aim was to determine whether neurotologic findings are in accordance with the type of migraine and whether test findings differ from those of healthy controls.
  
  
  METHODS
  The authors examined 36 patients with various types of migraine classified by International Headache Society criteria. Comprehensive neurotologic tests were performed between attacks: video-oculography (VOG), electronystagmography, static posturography, and audiometry on 12 patients with migraine with aura (MA) and 24 patients with migraine without aura (MO). Results were compared to those of test-specific nonmigrainous control groups. Only eight migraineurs (six with MA and two with MO) had vertigo or dizziness.
  
  
  RESULTS
  Despite the absence of clinical neurotologic symptoms, most of the patients with migraine (83%) showed abnormalities in at least one of these tests. Both migraine types differed significantly from the control group (in VOG, in saccadic accuracy, and in static posturography). Vestibular findings tended to be more severe in MA than in MO.
  
  
  CONCLUSIONS
  These data suggest that interictal neurotologic dysfunction in MA and MO share similar features and that the defective oculomotor function is mostly of vestibulocerebellar origin.
authors.affiliation: Department of Neurology, Helsinki University Central Hospital, Finland. hanna.harno@hus.fi
authors.forename: H
authors.initials: H
authors.lastname: Harno
authors.forename: T
authors.initials: T
authors.lastname: Hirvonen
authors.forename: M A
authors.initials: MA
authors.lastname: Kaunisto
authors.forename: H
authors.initials: H
authors.lastname: Aalto
authors.forename: H
authors.initials: H
authors.lastname: Levo
authors.forename: E
authors.initials: E
authors.lastname: Isotalo
authors.forename: M
authors.initials: M
authors.lastname: Kallela
authors.forename: J
authors.initials: J
authors.lastname: Kaprio
authors.forename: A
authors.initials: A
authors.lastname: Palotie
authors.forename: M
authors.initials: M
authors.lastname: Wessman
authors.forename: M
authors.initials: M
authors.lastname: Färkkilä
mesh_terms: D000328:Adult; D001299:Audiometry; D002526:Cerebellar Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D004584:Electronystagmography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D009460:Neurologic Examination; D004856:Postural Balance; D012016:Reference Values; D014717:Vertigo / Q000175:diagnosis; D014725:Vestibular Nerve / Q000503:physiopathology*; D000160:Vestibulocochlear Nerve Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology