title: Multiple neuronal connexins in the mammalian retina.
abstract: Gap junctions are abundant in the mammalian retina and many neuronal types form neural networks. Several different neuronal connexins have now been identified in the mammalian retina. Cx36 supports coupling in the AII amacrine cell network and is essential for processing rod signals. Cx36 is probably also responsible for photoreceptor coupling. Horizontal cells appear to be extensively coupled by either Cx50 or Cx57. These results indicate that multiple neuronal connexins are expressed in the mammalian retina and that different cell types express different connexins.
authors.affiliation: Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Houston, TX 77030, USA. Steve.Massey@uth.tmc.edu
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Massey
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: O'Brien
authors.forename: E Brady
authors.initials: EB
authors.lastname: Trexler
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Joyce W
authors.initials: JW
authors.lastname: Keung
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Mills
authors.forename: John
authors.initials: J
authors.lastname: O'Brien
mesh_terms: D025042:Amacrine Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D001710:Biotin / Q000031:analogs & derivatives* / Q000378:metabolism; D017630:Connexins / Q000378:metabolism*; D005136:Eye Proteins / Q000378:metabolism*; D017629:Gap Junctions / Q000378:metabolism / Q000502:physiology; D012160:Retina / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D017948:Retinal Rod Photoreceptor Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D000097004:Gap Junction delta-2 Protein; D000099264:Connexin 50
chemical_list: D001710:Biotin; D017630:Connexins; D005136:Eye Proteins; D000097004:Gap Junction delta-2 Protein; D000099264:Connexin 50; C070614:neurobiotin