Reaction of alkynes with iodine monochloride revisited.
6-Exo-dig and/or 7-endo-dig iodocyclization reactions of functionalized acetylenic derivatives with ICl are disfavored in comparison with the corresponding electrophilic addition reactions providing regioselectively (E)-1-chloro-2-iodoethene derivatives. On the contrary, 6-endo-digand 5-exo-dig iodocyclizations of methyl ynoates with ICl seem to be favored in comparison with the corresponding electrophilic addition reactions.
Bellina
Fabio
F
Dipartimento di Chimica e Chimica Industriale, University of Pisa, via Risorgimento 35, I-56126 Pisa, Italy. bellina@dcci.unipi.it
Colzi
Francesca
F
Mannina
Luisa
L
Rossi
Renzo
R
Viel
Stephane
S