Nephroblastoma (Wilms' tumour) diagnosed in the Department of Anatomical Pathology Medunsa/Ga-Rankuwa Hospital for the period 1980 to 1997.
OBJECTIVE
The aim of the analysis was to describe the clinicopathological features of Wilms' Tumour (WT) diagnosed in our Department and compare results to other WT Registers.


METHODS
All cases of WT for the period 1980 to 1997 were retrieved from the Register of Renal Tumours of Childhood.


METHODS
The Medical University of Southern Africa, Department of Anatomical Pathology and Department of Paediatrics, Ga-Rankuwa Hospital.


METHODS
A total of 171 cases of WT (97% of all renal tumours) were the subject of the analysis.


RESULTS
The age of the patients ranged from four to 216 months. The two sexes were represented equally. Tumours were solid in 73.9%, cystic in 20% and mixed in 6.1%. There were as many tumours involving the right kidney as those involving the left kidney. In nine cases WT was bilateral. Only 2.4% of tumours were in stage I and II. The mass of the kidney with tumour ranged from 50 g to 5,400 g and in diameter from three to 28 cm. Histopathologically classic, blastemal and stromal type were nearly equally represented. Follow up was very inadequate and in 66% of cases the fate of the patient remains unknown.


CONCLUSIONS
Occurrence of WT is similar to that reported from other regions of the world. Cases are in a more advanced stage than reported by SIOP and NWTS. Follow up is highly inadequate.
Lancaster
E J
EJ
Department of Anatomical Pathology, Medical University of Southern Africa (MEDUNSA).
Banach
L
L
Devilliers
F P
FP
D000293:Adolescent; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D009367:Neoplasm Staging; D009392:Nephrectomy; D012042:Registries / Q000706:statistics & numerical data; D009396:Wilms Tumor / Q000473:pathology* / Q000601:surgery