Improved synthesis of aza-bis(oxazoline) ligands.
A straightforward synthesis of chiral aza-bis(oxazoline) (Azabox) ligands from commercially available amino alcohols is described. The new protocol allows access to previously reported Azabox ligands in considerably improved yields but also to new derivatives, including non-C2-symmetrical ones.
Werner
Heiko
H
Institut für Organische Chemie der Universität Regensburg, Universitätsstrasse 31, D-93040 Regensburg, Germany.
Vicha
Robert
R
Gissibl
Anja
A
Reiser
Oliver
O