title: Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults.
abstract: Nontyphoid Salmonella (NTS) bacteremia has a very high mortality and recurrence rate among human immunodeficiency virus (HIV)-infected Malawian adults. Concurrent schistosomal infection might cause persistence of NTS infection and poor response to antibiotic therapy. Therefore, we tested serum samples for Schistosoma-specific circulating anodic antigen to diagnose coinfection with schistosomiasis among consecutive HIV-positive adults with NTS bacteremia. The results suggest that active schistosomiasis is not associated with adverse outcome of NTS bacteremia in this population, in contrast to other groups.
authors.affiliation: Wellcome Trust Laboratories, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Chichiri, Malawi. mgordon@mlw.medcol.mw
authors.forename: Melita A
authors.initials: MA
authors.lastname: Gordon
authors.forename: Eduard E
authors.initials: EE
authors.lastname: Zijlstra
authors.forename: Cynthia W A
authors.initials: CW
authors.lastname: Naus
authors.forename: Leo G
authors.initials: LG
authors.lastname: Visser
authors.forename: Malcolm E
authors.initials: ME
authors.lastname: Molyneux
authors.forename: Lisette
authors.initials: L
authors.lastname: van Lieshout
mesh_terms: D000328:Adult; D000818:Animals; D000947:Antigens, Helminth / Q000097:blood; D016470:Bacteremia / Q000150:complications* / Q000401:mortality; D005260:Female; D006023:Glycoproteins / Q000097:blood; D006678:HIV; D015658:HIV Infections / Q000150:complications* / Q000401:mortality; D015801:Helminth Proteins / Q000097:blood; D006801:Humans; D008297:Male; D012480:Salmonella Infections / Q000150:complications* / Q000401:mortality; D012552:Schistosomiasis / Q000150:complications* / Q000401:mortality; D016896:Treatment Outcome
chemical_list: D000947:Antigens, Helminth; D006023:Glycoproteins; D015801:Helminth Proteins; C090907:circulating anodic antigen, Schistosoma mansoni