title: Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome.
abstract: In patients with troponin-negative acute coronary syndromes, creatine kinase (CK)-MB elevation predicts a significantly higher risk of death and major acute cardiac events compared with CK-MB negative patients. This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonstrate ST elevation by electrocardiogram.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor, Michigan, USA.
authors.forename: Kimberly C
authors.initials: KC
authors.lastname: Yee
authors.forename: Debabrata
authors.initials: D
authors.lastname: Mukherjee
authors.forename: Dean E
authors.initials: DE
authors.lastname: Smith
authors.forename: Eva M
authors.initials: EM
authors.lastname: Kline-Rogers
authors.forename: Jianming
authors.initials: J
authors.lastname: Fang
authors.forename: Rajendra H
authors.initials: RH
authors.lastname: Mehta
authors.forename: Yassar
authors.initials: Y
authors.lastname: Almanaseer
authors.forename: Eyad
authors.initials: E
authors.lastname: Akhras
authors.forename: Jeanna V
authors.initials: JV
authors.lastname: Cooper
authors.forename: Kim A
authors.initials: KA
authors.lastname: Eagle
mesh_terms: D000208:Acute Disease; D000368:Aged; D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000150:complications / Q000401:mortality; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010359:Patient Readmission / Q000706:statistics & numerical data; D011237:Predictive Value of Tests; D011379:Prognosis; D013577:Syndrome; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D007527:Isoenzymes; D019210:Troponin I; D003402:Creatine Kinase