title: Cup-ling oskar RNA localization and translational control.
abstract: RNA localization and spatially restricted translational control can serve to deploy specific proteins to particular places within a cell. oskar (osk) RNA is a key initiatior of posterior patterning and germ cell specification in Drosophila, and its localization and translation are under elaborate control. In this issue, Wilhelm et al. (2003) show that the protein Cup both promotes osk localization and participates in repressing translation of unlocalized osk.
authors.affiliation: Department of Biology, McGill University, 115 West University Parkway, Montréal, Québec, Canada. Paul.Lasko@mcgill.ca
authors.forename: Paul
authors.initials: P
authors.lastname: Lasko
mesh_terms: D000818:Animals; D019070:Cell Lineage / Q000235:genetics; D029721:Drosophila Proteins / Q000235:genetics*; D005854:Germ Cells / Q000166:cytology / Q000378:metabolism*; D019476:Insect Proteins / Q000235:genetics*; D009865:Oocytes / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D009866:Oogenesis / Q000235:genetics*; D014176:Protein Biosynthesis / Q000235:genetics; D012313:RNA / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics
chemical_list: D029721:Drosophila Proteins; D019476:Insect Proteins; D012097:Repressor Proteins; C105238:cup protein, Drosophila; C091675:osk protein, Drosophila; D012313:RNA