[Examination and significance of semenial prostate specific antigen in infertile patients].
OBJECTIVE
To investigate the significance of prostate specific antigen (PSA) examination in seminal plasma of infertile patients.


METHODS
Eighty-five infertile patients were collected randomly. The level of PSA in seminal plasma was detected by ELISA method. The correlations between PSA and several seminal parameters including sperm density, motility and acid phosphatase (ACP) were analyzed.


RESULTS
The PSA, ACP concentrations and sperm motility in 65 cases of abnormal liquefaction patients were obviously lower than those in normal liquefaction patients(P < 0.01). But there were no significant differences in sperm density among the three groups(P > 0.05). PSA levels were significantly correlated with ACP and sperm motility(P < 0.01).


CONCLUSIONS
The seminal PSA in infertile patients is markedly correlated with semen liquefaction. The abnormal quality and quantity of PSA can result in a depression of sperm motility and subinfertility.
Yang
Guo-Zong
GZ
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Zhu
Pei-Yuan
PY
Hu
Yu-An
YA
Ge
Yi-Feng
YF
D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism*; D008297:Male; D017430:Prostate-Specific Antigen / Q000032:analysis*; D012661:Semen / Q000737:chemistry*; D013076:Sperm Count; D013081:Sperm Motility
D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen