Lacrimo-auriculo-dento-digital syndrome with QT prolongation.
We present a case of a young boy in whom lacrimo-auriculo-dental-digital (LADD) syndrome with QT prolongation was detected. According to Bazett's formula, corrected QT was 504 ms. There were no published data about LADD syndrome with QT prolongation. This is the first case concerning LADD syndrome associated with QT prolongation. It is known that deafness and QT prolongation occur in potassium channel dysfunction. QT prolongation and deafness may be associated with potassium channel dysfunction in patients with LADD syndrome. As a result QT prolongation may be a new component of the LADD syndrome.
Onrat
Ersel
E
Department of Cardiology, School of Medicine, Faculty of Science, Afyon Kocatepe University, Turkey. eronrat@aku.edu.tr
Kaya
Dayimi
D
Onrat
Serap Tutgun
ST
D000015:Abnormalities, Multiple / Q000175:diagnosis; D000293:Adolescent; D001842:Bone and Bones / Q000002:abnormalities / Q000000981:diagnostic imaging; D004431:Ear, External / Q000002:abnormalities* / Q000000981:diagnostic imaging; D004452:Echocardiography; D004562:Electrocardiography; D006311:Hearing Disorders / Q000151:congenital / Q000175:diagnosis; D006329:Heart Conduction System / Q000002:abnormalities*; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000151:congenital* / Q000175:diagnosis*; D008297:Male; D009262:Nails / Q000000981:diagnostic imaging; D009264:Nails, Malformed; D011859:Radiography; D013577:Syndrome; D014071:Tooth Abnormalities / Q000175:diagnosis*