title: Evidence of enhanced reactivity of DAAP nucleophiles toward dephosphorylation and deacylation reactions in cationic gemini micellar media.
abstract: 4,4'-(Dialkylamino)pyridine (DAAP)-based compounds 1-4 catalytically cleave hydrophobic organophosphate and carboxylate esters in various host micellar aggregates at mildly alkaline pH. The role of the micellar reaction medium in such esterolytic reactions has been carefully examined in this work. The cationic gemini surfactant based micellar aggregates provide more than 1 order of magnitude better reaction medium for the above reactions than their conventional single-chain, single-charge, cationic cetyl trimethylammonium bromide (CTABr) micelles. The catalytic turnover behavior of DAAP nucleophiles in the presence of excess substrates is also retained in gemini micellar media.
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science, Bangalore, India 560 012. sb@orgchem.iisc.ernet.in
authors.forename: Santanu
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: V Praveen
authors.initials: VP
authors.lastname: Kumar