Immunopathogenesis of cutaneous T-cell lymphomas.
The physiopathology of cutaneous T-cell lymphomas is poorly understood. Little is known about the factors that drive a mature T-cell clone to accumulate in the skin, despite the feedback mechanisms that normally control immune response. This article discusses the identification of tumor-specific antigens.
Bagot
Martine
M
Department of Dermatology, Paris XII University, Inserm U448, 8 Rue du General Sarrail, 94010 Creteil, France. martine.bagot@hmn.ap-hop-paris.fr
Boumsell
Laurence
L
Bensussan
Armand
A
D015703:Antigens, CD / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis*; D045744:Cell Line, Tumor / Q000737:chemistry / Q000473:pathology; D006801:Humans; D016130:Immunophenotyping; D000075362:Leukocyte Immunoglobulin-like Receptor B1; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D014411:Neoplastic Stem Cells / Q000737:chemistry / Q000473:pathology*; D011956:Receptors, Cell Surface / Q000032:analysis; D011971:Receptors, Immunologic / Q000032:analysis; D054340:Receptors, KIR; D012751:Sezary Syndrome / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D016176:T-Lymphocyte Subsets / Q000737:chemistry / Q000473:pathology*
D015703:Antigens, CD; D000951:Antigens, Neoplasm; C105299:LILRB1 protein, human; D000075362:Leukocyte Immunoglobulin-like Receptor B1; D009363:Neoplasm Proteins; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic; D054340:Receptors, KIR; C429763:SC5 receptor, human