title: The microtubule lattice--dynamic instability of concepts.
abstract: In the February 1995 issue of trends in CELL BIOLOGY, Linda Amos presented her view of our current understanding of the lattice structure of microtubules, 20 years after publication of the original paper describing the A- and B-lattices for flagellar microtubules. However, the question of the lattices of flagellar and cytoplasmic microtubules remains a matter for debate. In this article, Eckhard Mandelkow, Young-Hwa Song and Eva-Maria Mandelkow argue that the B-lattice is predominant, implying structural asymmetry for most microtubules.
authors.affiliation: Max-Planck Unit for Structural Molecular Biology, DESY, Notkestrasse 85, D-22603 Hamburg, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Mandelkow
authors.forename: Y H
authors.initials: YH
authors.lastname: Song
authors.forename: E M
authors.initials: EM
authors.lastname: Mandelkow