The ice worm, Mesenchytraeus solifugus, elevates adenylate levels at low physiological temperature.
The ice worm, Mesenchytraeus solifugus, is among a few metazoan species that survive exclusively in glacier ice/snow. In this study, we demonstrate that ice worm adenylate levels [i.e. adenosine 5'-triphosphate (ATP), ADP and AMP] are maintained at levels well above their mesophilic counterparts, and that their response to temperature change is distinctly opposite, namely, ice worms increase energy levels as temperatures fall. Initially, this response is characterized by a sharp spike in [ATP] and the adenylate energy charge (even at sub-zero temperatures), which is followed by corresponding increases in [ADP] and [AMP] within a few days. These results suggest that ice worms have evolved a compensatory mechanism by which gains in adenylate nucleotides off-set, at least in part, the inherent lethargy and death usually associated with cold temperature.
Napolitano
Michael J
MJ
Biology Department, The State University of New Jersey, Rutgers, Camden, NJ 08102, USA.
Nagele
Robert G
RG
Shain
Daniel H
DH
D000064:Acclimatization / Q000502:physiology*; D000227:Adenine Nucleotides / Q000378:metabolism*; D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000413:Alaska; D000818:Animals; D003081:Cold Climate; D003080:Cold Temperature; D006376:Helminths / Q000502:physiology*; D007053:Ice
D000227:Adenine Nucleotides; D007053:Ice; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate