title: Inhibiting cell division in Escherichia coli has little if any effect on gene expression.
abstract: DNA microarrays were used to compare gene expression in dividing and nondividing (filamentous) cultures of Escherichia coli. Although cells from these cultures differed profoundly in morphology, their gene expression profiles were nearly identical. These results extend previous evidence that there is no division checkpoint in E. coli, and progression through the cell cycle is not regulated by the transcription of different genes during different parts of the cell cycle.
authors.affiliation: Department of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.
authors.forename: S J Ryan
authors.initials: SJ
authors.lastname: Arends
authors.forename: David S
authors.initials: DS
authors.lastname: Weiss
mesh_terms: D002453:Cell Cycle; D002455:Cell Division; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D020411:Oligonucleotide Array Sequence Analysis; D014158:Transcription, Genetic