Synthetic approaches to guanacastepenes. Enantiospecific syntheses of BC and AB ring systems of guanacastepenes and rameswaralide.
[reaction: see text] A simple and efficient approach for the BC and AB ring systems of the novel diterpenes guanacastepenes and rameswaralide starting from the readily and abundantly available monoterpene (R)-carvone employing RCM reaction as the key step is described.
Srikrishna
A
A
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560012, India. ack@orgchem.iisc.ernet.in
Dethe
Dattatraya H
DH
D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000138:chemical synthesis*; D008968:Molecular Conformation; D013237:Stereoisomerism
D004224:Diterpenes; C409194:guanacastepene; C496873:rameswaralide