Facile O-arylation of phenols and carboxylic acids.
[reaction: see text] A facile, transition-metal-free O-arylation procedure for phenols and aromatic carboxylic acids has been developed that affords good to excellent yields of arylated products under very mild reaction conditions. A methoxy-substituted aryl triflate affords O-arylated products in high yields with excellent regioselectivity. This chemistry tolerates a variety of functional groups.
Liu
Zhijian
Z
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Larock
Richard C
RC