[Effect of Milkvetch Injection on cardiac function and hemodynamics in children with tetralogy of Fallot after radical operation].
OBJECTIVE
To evaluate the effect of Milkvetch Injection (MI) on cardiac function and hemodynamics in children with tetralogy of Fallot after radical operation.


METHODS
Thirty-two children with tetralogy of Fallot were divided into two groups, the 20 patients in the control group treated with conventional treatment and the 12 patients in the treated group treated with 15 ml of MI every 12 hrs for 7 days. The cardiac function and hemodynamic parameters were determined by echocardiography and thermodilution catheter inserted in pulmonary artery.


RESULTS
Patients' cardiac function and hemodynamic parameters were improved significantly 1 hr after administering 15 ml of MI Injection, but restored to the level before medication in 2-4 hrs. Administering MI injection for successive 7 days could gradually improve patients' cardiac function and hemodynamic parameters after operation, and the improvement became more evident with the prolonging time of medication. The intubation time, intensive care unit duration and the time of intravenously administration of inotropic drugs in the treated group were significantly shorter than those in the control group (P < 0.01).


CONCLUSIONS
MI could significantly improve the hemodynamics and cardiac function, and shorten the recovery time in children with tetralogy of Fallot after radical operation.
Li
Zi-pu
ZP
Affiliated Hospital of Qingdao University, Medical College, Shandong 266003.
Cao
Qian
Q
Xing
Quan-sheng
QS
D027883:Astragalus Plant; D027885:Astragalus propinquus; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008517:Phytotherapy; D011184:Postoperative Period; D013771:Tetralogy of Fallot / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D016276:Ventricular Function
D004365:Drugs, Chinese Herbal; C027492:Huang Qi