Short-term treatment of actinomycosis: two cases and a review.
Recommendations for prolonged penicillin treatment of actinomycosis date from the early antibiotic era, when patients often presented with neglected, advanced disease and received interrupted therapy at suboptimal dosages. This report describes cases of esophageal and of cervicofacial actinomycosis treated successfully with short-term antibiotic therapy and reviews the literature. Many patients are cured with <6 months of antibiotic therapy. If short-term antibiotic treatment is attempted, the clinical and radiological response should be closely monitored. Cervicofacial actinomycosis is especially responsive to brief courses of antibiotic treatment.
Sudhakar
Selvin S
SS
Division of Infectious Diseases, Caritas Saint Elizabeth's Medical Center, Boston, MA 02135, USA.
Ross
John J
JJ
D000197:Actinomycosis, Cervicofacial / Q000188:drug therapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D010406:Penicillins / Q000627:therapeutic use*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D010406:Penicillins