title: Scalable multichannel MRI data acquisition system.
abstract: A scalable multichannel digital MRI receiver system was designed to achieve high bandwidth echo-planar imaging (EPI) acquisitions for applications such as BOLD-fMRI. The modular system design allows for easy extension to an arbitrary number of channels. A 16-channel receiver was developed and integrated with a General Electric (GE) Signa 3T VH/3 clinical scanner. Receiver performance was evaluated on phantoms and human volunteers using a custom-built 16-element receive-only brain surface coil array. At an output bandwidth of 1 MHz, a 100% acquisition duty cycle was achieved. Overall system noise figure and dynamic range were better than 0.85 dB and 84 dB, respectively. During repetitive EPI scanning on phantoms, the relative temporal standard deviation of the image intensity time-course was below 0.2%. As compared to the product birdcage head coil, 16-channel reception with the custom array yielded a nearly 6-fold SNR gain in the cerebral cortex and a 1.8-fold SNR gain in the center of the brain. The excellent system stability combined with the increased sensitivity and SENSE capabilities of 16-channel coils are expected to significantly benefit and enhance fMRI applications.
authors.affiliation: Functional MRI Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892-1065, USA.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Bodurka
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Ledden
authors.forename: Peter
authors.initials: P
authors.lastname: van Gelderen
authors.forename: Renxin
authors.initials: R
authors.lastname: Chu
authors.forename: Jacco A
authors.initials: JA
authors.lastname: de Zwart
authors.forename: Doug
authors.initials: D
authors.lastname: Morris
authors.forename: Jeff H
authors.initials: JH
authors.lastname: Duyn
mesh_terms: D001921:Brain / Q000033:anatomy & histology*; D004581:Electronics; D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D019047:Phantoms, Imaging; D012984:Software