title: [Non-invasive, multi detector row (MDR) CT based computational fluid dynamics (CFD) analysis of hemodynamics in infrarenal abdominal aortic aneurysm (AAA) before and after endovascular repair].
abstract: OBJECTIVE
  Simulation, description and analysis of dynamic pressure in infrarenal abdominal aortic aneurysms (AAA) before and after endovascular repair.
  
  
  METHODS
  During March 1996 and May 2001, 13 patients with AAA underwent endovascular treatment. The MDR-CT scans of these patients were used for the non-invasive analysis of the hemodynamics in the aorta with CFD software before and after endovascular repair. One pre-interventional and three post-interventional CT scans were analyzed for each patient.
  
  
  RESULTS
  Compared to the pre-interventional simulation, endovascular treatment led to an average dynamic pressure decrease of 1057 Pa in 10 of 13 patients. During the subsequent course, the median of the dynamic pressure decreased in 8 of 13 patients. Vulnerable regions initially identified as high-pressure regions, like the docking area or the second stent limb, adapted to the pressure in the surrounding tissue in the course of time.
  
  
  CONCLUSIONS
  CFD-based blood flow simulation offers the opportunity to analyze dynamic pressure in AAA before and after endovascular repair and allows a prognostic statement as to the possible homogenization of the pressure in abdominal stent-grafts.
authors.affiliation: Abteilung für Diagnostische Radiologie, Universitätsklinikum Ulm. markus.juchems@medizin.uni-ulm.de
authors.forename: M S
authors.initials: MS
authors.lastname: Juchems
authors.forename: D
authors.initials: D
authors.lastname: Pless
authors.forename: T R
authors.initials: TR
authors.lastname: Fleiter
authors.forename: A
authors.initials: A
authors.lastname: Gabelmann
authors.forename: F
authors.initials: F
authors.lastname: Liewald
authors.forename: H J
authors.initials: HJ
authors.lastname: Brambs
authors.forename: A J
authors.initials: AJ
authors.lastname: Aschoff
authors.forename: A J
authors.initials: AJ
authors.lastname: Aschpoff
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D005500:Follow-Up Studies; D006439:Hemodynamics; D018056:Hemorheology; D006801:Humans; D008962:Models, Theoretical; D011379:Prognosis; D012984:Software; D015607:Stents; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*