[Genetic and molecular characteristics of a new natural haplotype twMP1 of the house mouse (Mus domesticus R.) from Peru].
A new natural haplotype, twWP1, found in a population of house mouse Mus domesticus from Peru, was subjected to genetic and molecular analyses. Experiments were performed to study the complementation of the new haplotype, fertility of twMP1/tx heterozygotes, and transmission ratio distortion (TRD) of the t-carrying chromosome in the progeny of heterozygous males. Molecular analysis included blot hybridization with t-specific probes Tu48, Tu66, and Tu119. The results were collated with the structure and properties of the t complex, and the new haplotype was identified as a complete lethal one.
Safronova
L D
LD
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, 119071 Russia.
Shustrova
I V
IV
D000818:Animals; D006239:Haplotypes; D008297:Male; D051379:Mice / Q000235:genetics*; D008808:Mice, Inbred CBA / Q000235:genetics; D015335:Molecular Probes; D009693:Nucleic Acid Hybridization
D015335:Molecular Probes