title: Dorsoventral patterning: a serpin pinned down at last.
abstract: Dorsoventral patterning in Drosophila has long been known to involve a cascade of proteases, held in the inactive zymogen state prior to signaling. At long last, the prediction that a protease inhibitor is involved in this pathway has been shown to be true, with the identification of a serpin that plays a key part in Drosophila embryonic patterning.
authors.affiliation: Department of Biology, New York University, 100 Washington Square East, New York, New York 10003, USA. chris.rushlow@nyu.edu
authors.forename: Chris
authors.initials: C
authors.lastname: Rushlow
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D004330:Drosophila / Q000196:embryology* / Q000378:metabolism; D029721:Drosophila Proteins / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism; D012697:Serine Endopeptidases / Q000378:metabolism; D015843:Serpins / Q000378:metabolism*; D015398:Signal Transduction; D051193:Toll-Like Receptors
chemical_list: D029721:Drosophila Proteins; D011956:Receptors, Cell Surface; D015843:Serpins; C468118:Spn27A protein, Drosophila; C068721:Tl protein, Drosophila; D051193:Toll-Like Receptors; D012697:Serine Endopeptidases; C078099:ea protein, Drosophila