title: Illuminating the molecular basis of gene-for-gene resistance; Arabidopsis thaliana RRS1-R and its interaction with Ralstonia solanacearum popP2.
abstract: Elucidation of the molecular basis of gene-for-gene interactions between disease-resistance (R) genes and pathogen avirulence (avr) genes has been a Holy Grail of plant pathology for the past decade. Recent studies of the R-avr interaction between RRS1-R and popP2 by Laurent Deslandes et al. provide new insights and suggest a direct physical association of the encoded proteins in support of a simplistic receptor-ligand model. However, careful consideration of the experimental findings reveals that they could also be explained by molecular linker proteins that mediate formation of a PopP2 and RRS1-R uniting complex.
authors.affiliation: Institute of Genetics, Martin-Luther-Universität Halle-Wittenberg, 06099 (Saale), Halle, Germany. lahaye@genetik.uni-halle.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Lahaye
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000382:microbiology*; D007113:Immunity, Innate / Q000235:genetics*; D008954:Models, Biological; D010935:Plant Diseases / Q000382:microbiology; D043368:Ralstonia solanacearum / Q000472:pathogenicity*; D014774:Virulence