Erdheim-chester disease mimicking multiple meningiomas syndrome.
We describe a rare case of non-Langerhans histiocytosis, consistent with Erdheim-Chester disease (ECD), which presented with lesions resembling multiple meningiomas. The patient was initially evaluated for migraine headaches. Initial MR imaging demonstrated a parasellar mass and a second mass near the torcula considered to represent meningiomas. Within 1 year, he developed bilateral orbital lesions surrounding both optic nerves, which were also considered meningiomas. Biopsy of one orbital mass revealed a non-Langerhans histiocytosis. Subsequently, soft tissue masses, a pericardial effusion, and bone lesions consistent with ECD were identified.
Johnson
Mahlon D
MD
Department of Pathology, Vanderbilt Medical School, Nashville, TN 37232, USA.
Aulino
Joseph P
JP
Jagasia
Madan
M
Mawn
Louise A
LA
D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D031249:Erdheim-Chester Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology; D008881:Migraine Disorders / Q000175:diagnosis / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis / Q000473:pathology; D013577:Syndrome