title: Fatigue, psychological distress, coping and quality of life in patients with uterine cancer.
abstract: BACKGROUND
  Cancer-related fatigue (CRF) is a subjectively experienced symptom that is multidimensional and multifactorial. Patients with cancer have identified fatigue as one of the major troubling symptoms and the primary cause of distress in their lives.
  
  
  OBJECTIVE
  The major aim of the study was to examine how patients diagnosed with uterine cancer describe their experience of fatigue, psychological distress, coping resources and quality of life. A secondary aim was to describe the relationship between selected variables.
  
  
  METHODS
  A descriptive and correlational design was used and the study was conducted at a university hospital in Sweden. The study population consisted of women, diagnosed with uterine cancer, who where scheduled to receive curative external radiation therapy. Sixty women participated in the study and data were collected through self-report instruments. Demographic and clinical data were extracted from patient records. The data were collected during year 2000-2002. The Conceptual Model of Symptom Management was used as a framework to guide the study.
  
  
  RESULTS
  Patients experienced a low grade of fatigue and psychological distress, but their functional status and global quality of life was high. Significant correlations were found between general fatigue and anxiety and also between general fatigue and depression. There was a significant negative correlation between general fatigue and coping resources. Depression explained 44% of the variance in general fatigue.
  
  
  CONCLUSIONS
  The findings provide knowledge about predictors of CRF in women with uterine cancer, and can serve as a basis for future longitudinal studies in which different prophylactic strategies against therapy-related fatigue are prospectively studied.
authors.affiliation: Department of Oncology, Sahlgrenska University Hospital, The Sahlgrenska Academy at Göteborg University, Institute of Nursing, Gothenburg, Sweden. karin.ahlberg@vgregion.se
authors.forename: Karin
authors.initials: K
authors.lastname: Ahlberg
authors.forename: Tor
authors.initials: T
authors.lastname: Ekman
authors.forename: Arne
authors.initials: A
authors.lastname: Wallgren
authors.forename: Fannie
authors.initials: F
authors.lastname: Gaston-Johansson
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D005221:Fatigue / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D013315:Stress, Psychological / Q000209:etiology; D013548:Sweden; D014594:Uterine Neoplasms / Q000150:complications / Q000523:psychology*