[Experimental study on olfactory evoked potential in rabbits].
OBJECTIVE
To observe olfactory evoked potential(OEPs) produced by electrical stimulation of the olfactory mucosa and to find out an objective way to appraise olfactory function.


METHODS
A bipolar stimulus electrode was placed on the olfactory mucosa of adult health rabbits via anterior naris. Olfactory evoked potential was recorded at headtop after being given a 0.5-4.0 mA current to the mucosa. And we also investigated the effect of stimulus parameters and stimulus location to the wave form of OEPs.


RESULTS
Triphasic negative-positive-negative evoked potentials were recorded from the surface of the frontal head close to olfactory bulb. Latent period of three waves respectively was N(1)20.6 ms, P(1)33.5 ms, N(2)58.3 ms.


CONCLUSIONS
In general, the OEPs were composed of triphasic negative-positive-negative complexes. The waveforms were stable and could be repeated well. Each parameter was useful for estimating the olfactory function.
Wei
Yongxiang
Y
Department of Otolaryngology-Head and Neck Surgery, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730.
Han
Demin
D
Cai
Zhen
Z
Yang
Ling
L
Liu
Xiaochao
X
Xian
Mu
M
Zhang
Xiaobin
X
D000818:Animals; D004558:Electric Stimulation; D004566:Electrodes; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D008297:Male; D009297:Nasal Mucosa / Q000502:physiology; D009833:Olfactory Pathways / Q000502:physiology*; D011817:Rabbits