title: Diffuse leptomeningeal hyperintensity on fluid-attenuated inversion recovery MR images in neurocutaneous melanosis.
abstract: Neurocutaneous melanosis (NCM) is a rare neuroectodermal dysplasia characterized by large or multiple cutaneous congenital pigmented nevi and benign or malignant melanocytic tumors of the leptomeninges. Although the MR manifestations of this disease have been reported in a small series of cases, the usefulness of fluid-attenuated inversion recovery (FLAIR) MR findings has not been documented. We present a case of NCM that showed diffuse leptomeningeal hyperintensity on FLAIR images. This FLAIR finding may be a clue to the detection of leptomeningeal abnormalities in NCM.
authors.affiliation: Department of Radiology, Mie University School of Medicine, Tsu, Mie, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Hayashi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Maeda
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Maji
authors.forename: Toshio
authors.initials: T
authors.lastname: Matsubara
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tsukahara
authors.forename: Kan
authors.initials: K
authors.lastname: Takeda
mesh_terms: D000015:Abnormalities, Multiple / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging; D002648:Child; D004058:Diffusion; D005625:Frontal Lobe / Q000002:abnormalities / Q000000981:diagnostic imaging; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging; D020300:Intracranial Hemorrhages / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008548:Melanosis / Q000134:cerebrospinal fluid / Q000151:congenital / Q000000981:diagnostic imaging*; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging / Q000556:secondary; D008578:Meninges / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D020752:Neurocutaneous Syndromes / Q000134:cerebrospinal fluid / Q000151:congenital / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed