[Guillain-Barré syndrome revealing visceral leishmaniasis in an immunocompetent woman].
Visceral leishmaniasis is an endemic parasitic infection rarely observed in association with Guillain-Barré syndrome in immunocompetent patients. A 40-year-old immunocompetent woman was admitted to our unit with recent onset difficulty in walking. The neurological examination and electrophysiological study led to the diagnosis of Guillain-Barré syndrome. During hospitalization, she developed cytopenia involving all three lines revealing visceral leishmaniasis. A few cases of visceral leishmaniasis with neuropathy have been reported, mainly in tropical regions. Neuropathological manifestations of visceral leishmaniasis are probably underestimated. The question is whether Guillain-Barré syndrome and visceral leishmaniasis are causally related.
Attarian
S
S
Service de Neurologie et des Maladies Neuromusculaires, CHU La Timone, Marseille. sattarian@ap-hm.fr
Serratrice
J
J
Mazodier
C
C
Disdier
P
P
Azulay
J-P
JP
Pouget
J
J
D000328:Adult; D000906:Antibodies / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D005732:Gangliosides / Q000276:immunology; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000276:immunology* / Q000821:virology; D006801:Humans; D007121:Immunocompetence; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000276:immunology* / Q000469:parasitology; D008214:Lymphocytes / Q000276:immunology; D008279:Magnetic Resonance Imaging; D009431:Neural Conduction / Q000502:physiology; D010525:Peripheral Nerves / Q000276:immunology / Q000469:parasitology / Q000821:virology
D000906:Antibodies; D005732:Gangliosides; C039129:GQ1b ganglioside