title: Larvicidal activity of latex and stem bark of Euphorbia tirucalli plant on the mosquito Culex quinquefasciatus.
abstract: The methanolic, chloroform and ether extracts of Euphorbia tirucalli latex and stem bark were evaluated for larvicidal activity against laboratory-reared larvae of Culex quinquefasciatus (Diptera: Culicidae), vector of the brancroftian filariasis and worst urban nuisance mosquito. The latex extracts contain more potent larvicidal components (177.14 mg/L-326.37 mg/L) than the stem bark extracts (237.663 mg/L-513.39 mg/L). The order of toxicity (LC50) for the latex extracts was Methanol extract (177.14 mg/L) > Chloroform (200.76 mg/L) > Ether (326.37 mg/L) while the rank of order of toxicity (LC50) of stem bark extracts was Ether (237.66 mg/L) > Chloroform (343.515 mg/L) > Methanol (513.387 mg/L), Higher doses (LC90 24 h of mosquito larvae) of each extract did not cause any mortality among fishes after 24 h. The study gave a weight into the possibility of formulating suitable preparation from the latex and stem bark extracts of the plant for use in mosquito control programme.
authors.affiliation: Natural Product Laboratory, Department of Zoology D.D.U. Gorakhpur University, Gorakhpur.
authors.forename: Rajeshwari
authors.initials: R
authors.lastname: Yadav
authors.forename: V K
authors.initials: VK
authors.lastname: Srivastava
authors.forename: Ramesh
authors.initials: R
authors.lastname: Chandra
authors.forename: Ajay
authors.initials: A
authors.lastname: Singh
mesh_terms: D000818:Animals; D003465:Culex / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D028481:Euphorbia; D007840:Latex / Q000302:isolation & purification* / Q000494:pharmacology; D024301:Plant Bark; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D007840:Latex; D010936:Plant Extracts