title: Role of proton magnetic resonance spectroscopy in the diagnosis of gliomatosis cerebri: a unique pattern of normal choline but elevated Myo-inositol metabolite levels.
abstract: A patient with histologically proven gliomatosis cerebri presented with a normal choline level but a markedly abnormal elevated myo-inositol level on magnetic resonance (MR) spectroscopy. We describe the case presentation, imaging findings (in particular, the unique MR spectroscopic pattern), and their significance regarding the diagnosis of this relatively rare neoplasm.
authors.affiliation: Department of Radiology, Medical Center, University of California-San Diego, 200 W. Arbor Drive, San Diego, CA 92103, USA.
authors.forename: Aurea V R
authors.initials: AV
authors.lastname: Mohana-Borges
authors.forename: Steven G
authors.initials: SG
authors.lastname: Imbesi
authors.forename: Rosalind
authors.initials: R
authors.lastname: Dietrich
authors.forename: John
authors.initials: J
authors.lastname: Alksne
authors.forename: Darius K
authors.initials: DK
authors.lastname: Amjadi
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D002794:Choline / Q000032:analysis*; D006801:Humans; D007294:Inositol / Q000032:analysis*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology
chemical_list: D007294:Inositol; D002794:Choline