Successful living-related renal transplantation in a 2-year-old girl weighing less than 10 kilograms.
The success of renal transplantation for infants weighing less than 10 kg is very limited because of graft thrombosis. We report a successful living-related renal transplant in a 2-year-old girl weighing 9.5 kg. Chronic renal failure was diagnosed 1 month before the transplantation. Laparoscopic donor nephrectomy was performed to retrieve the left kidney of her father, a 36-year-old man weighing 70 kg, and the recipient operation was conducted via a right retroperitoneal approach. The right native kidney of the recipient was removed to accommodate the graft kidney during the transplant surgery. The graft renal artery, renal vein, and ureter were anastomosed to the recipient abdominal aorta, inferior vena cava, and bladder, respectively. The abdominal fascial defect was closed with absorbable mesh grafting, and the skin was closed primarily. With intensive fluid therapy and monitoring after reperfusion of the graft kidney, the patient recovered uneventfully and was discharged with an FK506-based immunosuppressive regimen 2 weeks after the operation. Renal function was good, and serum creatinine was 0.5 mg/dL 6 months after the operation.
Tsai
Meng-Kun
MK
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Huang
Hui-Hsun
HH
Lai
I-Rue
IR
Tsau
Yong-Kwei
YK
Lee
Po-Huang
PH
D001835:Body Weight; D005260:Female; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D011182:Postoperative Care