Intervention of phenonium ion in Ritter reactions.
The transformation of phenylethyl chloride to 3,4-dihydroisoquinolines is shown to proceed via phenonium ion. The evidence comes from a study of dideuterated analogue 4, and the monomethylated and dimethylated compounds 2 and 3.
Ho
Tse-Lok
TL
Department of Applied Chemistry, National Chiao Tung University, Hsinchu, Taiwan, Republic of China. tlho@cc.nctu.edu.tw
Chein
Rong-Jie
RJ