title: Group B streptococcal necrotizing fasciitis and toxic shock-like syndrome: a case report and review of the literature.
abstract: We report the fourth case of group B streptococcal (GBS) necrotizing fasciitis and toxic shock-like syndrome. Since the mechanism of GBS toxic shock may be similar to Group A Streptococcus, intravenous immunoglobulin should be considered as an adjunct to clindamycin-based antibiotic therapy.
authors.affiliation: Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA 92134-1005, USA. nfcrum@nmcsd.med.navy.mil
authors.forename: Nancy F
authors.initials: NF
authors.lastname: Crum
authors.forename: Mark R
authors.initials: MR
authors.lastname: Wallace
mesh_terms: D000328:Adult; D002981:Clindamycin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D019115:Fasciitis, Necrotizing / Q000150:complications / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008297:Male; D018570:Risk Assessment; D012772:Shock, Septic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D016038:Skin Transplantation; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D002981:Clindamycin