title: [Behavior of bone formation around the porous-hollow cylindrical titanium implant composed of bone morphogenetic protein].
abstract: OBJECTIVE
  The purpose of this study was to observe the behavior of bone formation around the titanium-hollow porous cylinder implant composed of bovine bone morphogentic protein(bBMP).
  
  
  METHODS
  Porous-hollow cylinder titanium implant composed of bBMP was implanted into mandibule of dogs. Multiple fluorescent was labeled at different times and then LSCM was used to observe the newly formed bone around the complex implant.
  
  
  RESULTS
  The newly formed bone around the complex implant in experimental group was more obvious than that in other groups.
  
  
  CONCLUSIONS
  Earlier, longer and more new-bone formation can be induced by porous-hollow cylinder titanium implant composed of bBMP, and LSCM is an effective method to observe new bone formation around implant.
authors.affiliation: Department of Stomatology, Luhe Hospital, Beijin 101100, China.
authors.forename: Xiangling
authors.initials: X
authors.lastname: Liao
authors.forename: Shaowei
authors.initials: S
authors.lastname: Chen
authors.forename: Shengwei
authors.initials: S
authors.lastname: Li
mesh_terms: D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000494:pharmacology*; D002417:Cattle; D004285:Dogs; D005260:Female; D020007:Implants, Experimental; D008297:Male; D008334:Mandible / Q000503:physiopathology / Q000601:surgery*; D016348:Osseointegration; D010012:Osteogenesis / Q000187:drug effects*; D016062:Porosity; D011897:Random Allocation; D014025:Titanium
chemical_list: D019485:Bone Morphogenetic Proteins; D014025:Titanium