title: [Susac syndrome: a report of two cases].
abstract: OBJECTIVE
  To investigate the clinic characters and diagnosis of Susac syndrome.
  
  
  METHODS
  Two cases were systematically studied by the authors.
  
  
  RESULTS
  All the two cases were young women. The clinical manifestations include acute and subacute multifocal and diffuse encephalopathic symptoms, hearing loss, and visual loss. Diagnosis is facilitated by demonstration of retinal arteriolar occlusions without uveitis or keratoconjunctivitis, mid-to-low frequency unilateral or bilateral sensorineural hearing loss, and numerous small foci of increased signal in the white and gray matter on T2-weighted brain magnetic resonance imaging.
  
  
  CONCLUSIONS
  This rare syndrome often can be identified at an early stage with a careful history and physical examination. MRI, SPECT, retinal fluorescein angiography and audiometry will contribute to diagnosis.
authors.affiliation: Department of Neurology, the First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400016, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Yu
authors.forename: Guo-guang
authors.initials: GG
authors.lastname: Peng
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Wei-wei
authors.initials: WW
authors.lastname: Dong
authors.forename: Qiu-ming
authors.initials: QM
authors.lastname: Deng
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D015834:Cochlear Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011379:Prognosis; D012164:Retinal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D013577:Syndrome; D016896:Treatment Outcome