title: Clinical course and treatment results of breast cancer patients with ten or more positive axillary nodes.
abstract: Two-hundred and fifty-nine women with operable breast cancer, having more than 10 involved nodes without a distant metastasis, were treated with radical, modified radical or partial mastectomy with complete axillary dissection. Survival at 5 years was 63% and at 7 years 54%. Fifty-six per cent and 52% were disease free 5 and 7 years after initial therapy. Postmenopausal women had an overall survival rate of 64% and disease free survival rate of 61% while premenopausal women had an overall survival of 58% and disease free survival of 52%. Survival and disease free survival rate for those with 10-20 positive nodes were 65% and 69% respectively, while for those with more than 20 positive nodes the rates were 49% and 52% respectively; a statistically better survival in the 2nd group. Although the observational time of patients having adjuvant CEF is short, a better survival rate and disease free survival rate is possible in women treated with CEF.
authors.affiliation: 1st Department of Obstetrics and Gynaecology, Breast Oncology Unit, Athens University, Alexandra Hospital, Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Keramopoullos
authors.forename: N
authors.initials: N
authors.lastname: Louvrou
authors.forename: G
authors.initials: G
authors.lastname: Iatrakis
authors.forename: K
authors.initials: K
authors.lastname: Ampela
authors.forename: S
authors.initials: S
authors.lastname: Michalas