title: Progressive form of pulmonary Langenharns' cell histiocytosis in a female adult non-smoker.
abstract: Little is known about the cause, nature, treatment and prognosis of pulmonary Langerhans' cell histiocytosis (LCH) in adults. We report the case of a 44-year-old female non-smoker suffering from pulmonary histiocytosis who after a 7-year remission period relapsed with both lung and bone disease. Using a combination of corticosteroids, methotrexate and bone irradiation treatment, the patient achieved total disease remission. The patient was a non-smoking female who has had long-term and swift remission of the disease on two occasions.
authors.affiliation: Pulmonary Disease Clinic, Jordanovac, Croatia.
authors.forename: Dubravka
authors.initials: D
authors.lastname: Bencić
authors.forename: Silvana
authors.initials: S
authors.lastname: Smojver
authors.forename: Zagorka
authors.initials: Z
authors.lastname: Boras
authors.forename: Kristina
authors.initials: K
authors.lastname: Potocki
authors.forename: Drago
authors.initials: D
authors.lastname: Batinić
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D003131:Combined Modality Therapy; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D016130:Immunophenotyping; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D011878:Radiotherapy / Q000379:methods; D012008:Recurrence
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D008727:Methotrexate