title: [Associated brain anomalies and clinical findings in corpus callosum dysgenesis].
abstract: OBJECTIVE
  The aim of this study was to evaluate the relationship between the types of the corpus callosum dysgenesis, the associated brain anomalies and clinical findings.
  
  
  METHODS
  We analyzed the MR imaging findings in 169 patients with callosal dysgenesis. Corpus callosum dysgenesis was categorized into agenesis, hypogenesis and hypoplasia. The associated brain anomalies and clinical findings were evaluated.
  
  
  RESULTS
  Associated brain anomalies were observed in 148 patients (87.5%). Twenty-one patients (12.4%) had isolated corpus callosum dysgenesis. Dysgenesis included agenesis in 22 (%13), hypogenesis in 46 (27.2%), and hypoplasia in 101 (59.7%) patients. The clinical findings were most commonly observed in patients with hypoplasia.
  
  
  CONCLUSIONS
  The presence of corpus callosum dysgenesis is a strong indication of possible associated brain anomalies. Corpus callosum dysgenesis and associated brain anomalies should be investigated in children with developmental delay, seizures and microcephaly.
authors.affiliation: Inönü Universitesi Tip Fakültesi, Turgut Ozal Tip Merkezi, Radyodiagnostik Anabilim Dali, Malatya.
authors.forename: Alpay
authors.initials: A
authors.lastname: Alkan
authors.forename: Ramazan
authors.initials: R
authors.lastname: Kutlu
authors.forename: Tamer
authors.initials: T
authors.lastname: Baysal
authors.forename: Ahmet
authors.initials: A
authors.lastname: Siğirci
authors.forename: Tayfun
authors.initials: T
authors.lastname: Altinok
authors.forename: Ismet
authors.initials: I
authors.lastname: Orkan
authors.forename: Tarik
authors.initials: T
authors.lastname: Hallaç
authors.forename: Kaya
authors.initials: K
authors.lastname: Saraç
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D061085:Agenesis of Corpus Callosum; D002648:Child; D003337:Corpus Callosum / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008499:Medical Records; D009421:Nervous System Malformations / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology*; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology