title: VE-DIC light microscopy and the discovery of kinesin.
abstract: Major advances in science are often tightly coupled with the development of new technology. The discovery of kinesin is an excellent example of this principle. The new technology was video-enhanced differential interference contrast light microscopy, which provided the enormous gain in image contrast needed to detect and measure kinesin-based motility in living cells, cell extracts and in vitro motility assays.
authors.affiliation: Dept of Biology, University of North Carolina, Chapel Hill, NC 27599-3280, USA.
authors.forename: E D
authors.initials: ED
authors.lastname: Salmon