Patches, posts and fences: proteins and plasma membrane domains.
Recent findings have indicated the presence of micrometre-scale protein-based domains in the membranes of several cell types. What are the implications of this organization for membrane function? Here, Michael Edidin describes the formation of protein-based domains, and discusses their possible effects on protein interactions within the bilayer.
Edidin
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Biology Department, The John Hopkins University, Baltimore, MD 21218, USA.