title: Pregnancy in a breast cancer patient treated with a LHRH analogue at ablative doses.
abstract: A 36-year-old female diagnosed of breast cancer was treated with surgery, chemotherapy, radiotherapy and goserelin. After 17 months of uninterrupted therapy with this LHRH analogue at hormone suppressive doses, a 16-week gestation foetus was detected and the treatment was withdrawn. Although the drug was administered throughout the first 4 months of pregnancy it resulted in the term delivery of a healthy infant, and no foetal adverse effects were detected. A review of the influence of hormonal treatment for breast cancer on fertility and birth defects has been performed.
authors.affiliation: Medical Oncology Department, Hospital Universitario La Paz, Paseo de la Castellana, number 261, 28046 Madrid, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Jiménez-Gordo
authors.forename: E
authors.initials: E
authors.lastname: Espinosa
authors.forename: P
authors.initials: P
authors.lastname: Zamora
authors.forename: J
authors.initials: J
authors.lastname: Feliu
authors.forename: N
authors.initials: N
authors.lastname: Rodríguez-Salas
authors.forename: M
authors.initials: M
authors.lastname: González-Barón