title: Improving the O/W emusifying properties of rapeseed lecithin ethanol insoluble fraction by acetylation.
abstract: The effect of acetylation of rapeseed lecithin ethanol insoluble fraction (LEIF) containing 25% phosphatidylethanolamine (PE) on the O/W emulsifying properties was reported. In the study, acetic anhydride (50-150 mmol/100 g) and pyridine (0-30 mmole/100 g) were used. The PE conversion to N-acetyl-PE in LEIF determined by the HPLC method was varied from 18.2 to 84.7% and depended essentially on the acetylating agent amount and pyridine quantity used in acetylation. Emulsions of the O/W systems containing lecithin emulsifiers with different PE conversion degree were prepared and evaluated for its stability. It was found that the acetylation of LEIF improves its emulsifying properties and in the formation of emulsions containing soya oil, provided a decrease in oil droplet size and polydispersity index.
authors.affiliation: Department of Pharmaceutical Technology, Silesian Medical University, 4 Jagiellońska Str, 41-200 Sosnowiec, Poland.
authors.forename: Marian
authors.initials: M
authors.lastname: Sosada
authors.forename: Beata
authors.initials: B
authors.lastname: Pasker
authors.forename: Marzena
authors.initials: M
authors.lastname: Bogocz
mesh_terms: D000107:Acetylation; D029741:Brassica rapa / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D004655:Emulsions; D000431:Ethanol / Q000737:chemistry; D010713:Phosphatidylcholines / Q000737:chemistry*; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004655:Emulsions; D010713:Phosphatidylcholines; D012997:Solvents; D000431:Ethanol