Lambertellols A and B, novel 3,4-dihydronaphthalen-1(2H)-ones with spiro-butenolide produced by Lambertella sp.1346.
[structure: see text] Lambertella sp. 1346 was found to produce lambertellols A (1) and B (2) carrying a novel dihydronaphthalen-1(2H)-ones with spiro-1-furan-2(5'H)-one. The spiro-lactone ring moiety of both 1 and 2 were easily migrated to afford lambertellin, a known metabolite of Lambertella corni-maris. The absolute stereochemistry of these compounds was established on the basis of CD spectrum after chemical derivatization.
Murakami
Takanori
T
Faculty of Agriculture and Bioscience, Hirosaki University, 3-Bunkyo-cho, Hirosaki, 036-8561, Japan.
Morikawa
Yoshifumi
Y
Hashimoto
Masaru
M
Okuno
Toshikatsu
T
Harada
Yukio
Y
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000737:chemistry*; D001203:Ascomycota / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry*
D009281:Naphthalenes; D013141:Spiro Compounds; C492699:lambertellol A; C492700:lambertellol B; C004511:butenolide; D015107:4-Butyrolactone