title: Building an application framework for integrative genomics.
abstract: The accelerated pace of biological research and the current availability of whole-genome data sets provides significant new sources of functional insight. We designed an architecture and framework for software to query and explore such data in an orderly and iterative fashion. The architecture is intended to provide an extensible platform for developing web based bioinformatics applications and to offer a flexible and end-user-extensible software environment to explore and integrate disparate biological data sources. This will enable the user to explore existing relationships and discover new functional relationships among these data.
authors.affiliation: Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Heta N
authors.initials: HN
authors.lastname: Ray
authors.forename: Vamsi K
authors.initials: VK
authors.lastname: Mootha
authors.forename: Aziz A
authors.initials: AA
authors.lastname: Boxwala
mesh_terms: D019295:Computational Biology; D023281:Genomics; D016247:Information Storage and Retrieval; D020407:Internet; D012984:Software; D014584:User-Computer Interface