title: Telomeric position effect in yeast.
abstract: Telomeres are the physical ends of chromosomes. In yeast, when a gene is placed near a telomere, its transcription is repressed. Genes under the influence of this telomeric position effects switch between a repressed state and a transcriptionally active state, each of which is stable for many cell generations. Telomeric position effect may provide a model system for the study of heritable gene regulation in other, more complex organisms.
authors.affiliation: Fred Hutchinson Cancer Research Center, 1124 Columbia St, Seattle, WA 9810, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Sandell
authors.forename: V A
authors.initials: VA
authors.lastname: Zakian