Outcomes and indications of segmental pancreatectomy. Comparison with distal pancreatectomy.
OBJECTIVE
To preserve pancreatic function, segmental pancreatectomy has been proposed for benign or low-malignancy tumors in the pancreatic body. Indications for the procedure, however, are still controversial.


METHODS
In this study, we investigated the advantages and disadvantages of segmental pancreatectomy compared with distal pancreatectomy and subsequently determined indications for segmental pancreatectomy.


RESULTS
The distal pancreatectomy patients had shorter operation times, lower incidence of operative complications, and shorter hospital stays compared to segmental pancreatectomy patients. Endocrine function in distal pancreatectomy patients deteriorated compared to that of segmental pancreatectomy patients. The postoperative 75-gram oral glucose tolerance test showed a diabetic pattern in 3 of 7 distal pancreatectomy patients, whereas none of the segmental pancreatectomy patients became diabetic after surgery. The relation between the length of the removed pancreas and plasma glucose at 2 h after the 75-gram glucose intake showed a significant correlation.


CONCLUSIONS
According to our results, if the length of removed pancreas is longer than 12 cm, the patients will have a risk of acquiring diabetes. In those cases, the segmental pancreatectomy should be considered.
Shibata
Satoshi
S
Department of Surgery, Akita University, Akita, Japan. shibata@surg1.med.akita-u.ac.jp
Sato
Tsutomu
T
Andoh
Hideaki
H
Yasui
Ouki
O
Yoshioka
Masato
M
Kurokawa
Toshiaki
T
Watanabe
Go
G
Ise
Norihito
N
Kotanagi
Hitoshi
H
Asanuma
Yoshihiro
Y
Koyama
Kenji
K
D010129:4-Aminobenzoic Acid / Q000652:urine; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D003920:Diabetes Mellitus / Q000209:etiology; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000009:adverse effects / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000601:surgery*; D012189:Retrospective Studies
D001786:Blood Glucose; D010129:4-Aminobenzoic Acid