Factor Xa is a superior target to factor IIa for antithrombotic therapies.
Büller
Harry R
HR
Department of Vascular Medicine, Academic Medical Center University of Amsterdam, The Netherlands. M.M.Veendorp@amc.uva.nl
D000925:Anticoagulants / Q000494:pharmacology* / Q000627:therapeutic use; D065427:Factor Xa Inhibitors; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D011516:Prothrombin / Q000037:antagonists & inhibitors*; D013927:Thrombosis / Q000188:drug therapy / Q000517:prevention & control*
D000925:Anticoagulants; D065427:Factor Xa Inhibitors; D005343:Fibrinolytic Agents; D011516:Prothrombin; C025337:Factor IIa