title: Progressive multifocal leukoencephalopathy in a patient with X-linked agammaglobulinemia.
abstract: To our knowledge, this is the first case report describing progressive multifocal leukoencephalopathy (PML) associated with X-linked agammaglobulinemia. The JC virus was confirmed at autopsy and PML was diagnosed. Humoral immunodeficiency with normal cellular immunity could be infected with JCV.
authors.affiliation: Department of Pediatrics, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan. t-tera@cc.gifu-u.ac.jp
authors.forename: Takahide
authors.initials: T
authors.lastname: Teramoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Kaneko
authors.forename: Michinori
authors.initials: M
authors.lastname: Funato
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Sawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nagashima
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Hirose
authors.forename: Naomi
authors.initials: N
authors.lastname: Kondo
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D001707:Biopsy, Needle; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007577:JC Virus / Q000302:isolation & purification*; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D012131:Respiratory Insufficiency; D018570:Risk Assessment; D012720:Severity of Illness Index