title: Chance diagnosis of low stage non-metastasized adrenal cortical carcinoma in a young woman with retroperitoneal hemorrhage.
abstract: Adrenal cortical carcinoma (ACC), a rare and highly malignant neoplasm of the cortical tract of the adrenal gland, is usually diagnosed at an advanced stage of development and often when metastatic spread already has begun. We report a very rare case of low-stage, non-metastasized ACC, the first clinical appearance of which was a large retroperitoneal hemorrhage caused by the rupture of the neoplastic mass. To the best of our knowledge, this is the third reported case of ACC rupture.
authors.affiliation: Department of Pathological Anatomy, University of Trieste, Trieste, Italy. bussani@univ.trieste.it
authors.forename: Rossana
authors.initials: R
authors.lastname: Bussani
authors.forename: Debora
authors.initials: D
authors.lastname: Camilot
authors.forename: Carlo
authors.initials: C
authors.lastname: Trombetta
authors.forename: Furio
authors.initials: F
authors.lastname: Silvestri
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D018268:Adrenocortical Carcinoma / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D012187:Retroperitoneal Space