Distinguishing the hitchhiking and background selection models.
A simple method to distinguish hitchhiking and background selection is proposed. It is based on the observation that these models make different predictions about the average level of nucleotide diversity in regions of low recombination. The method is applied to data from Drosophila melanogaster and two highly selfing tomato species.
Innan
Hideki
H
Human Genetics Center, University of Texas Health Science Center, Houston, Texas 77030, USA. hideki.innan@uth.tmc.edu
Stephan
Wolfgang
W
D000818:Animals; D003198:Computer Simulation; D004331:Drosophila melanogaster / Q000235:genetics; D005787:Gene Frequency; D017344:Genes, Insect / Q000235:genetics; D017343:Genes, Plant / Q000235:genetics; D014644:Genetic Variation; D018551:Solanum lycopersicum / Q000235:genetics; D008957:Models, Genetic; D015233:Models, Statistical; D011995:Recombination, Genetic; D012641:Selection, Genetic