Improving the bacteriological diagnosis of tuberculous meningitis.
We made a bacteriological diagnosis of tuberculous meningitis in 107 of 132 (81%) adults with clinical tuberculous meningitis: acid-fast bacilli were seen in 77 of 132 (58%) and cultured from 94 of 132 (71%). Volume of cerebrospinal fluid, duration of symptoms, cerebrospinal fluid neutrophils, lactate, and glucose were all independently associated with bacteriological confirmation.
Thwaites
Guy E
GE
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam. gthwaites@hcm.vnn.vn
Chau
Tran Thi Hong
TT
Farrar
Jeremy J
JJ
D000328:Adult; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D011446:Prospective Studies; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid / Q000382:microbiology*