title: Common data element (CDE) management and deployment in clinical trials.
abstract: The NCI provides the cancer Data Standards Repository (caDSR) to support development and deployment of CDEs in cancer research. The caDSR, part of the NCI caCORE infrastructure, supports data management workflow requirements and adherence to ISO/IEC 11179 metadata standards. CDEs are developed using standard terminology from caCORE vocabulary services, and are then deployed to multi-site clinical trials data management systems. Here we describe the caDSR and how CDEs are managed and deployed in clinical research.
authors.affiliation: NCI Center for Bioinformatics, USA.
authors.forename: Denise B
authors.initials: DB
authors.lastname: Warzel
authors.forename: Christo
authors.initials: C
authors.lastname: Andonydis
authors.forename: Bill
authors.initials: B
authors.lastname: McCurry
authors.forename: Ram
authors.initials: R
authors.lastname: Chilukuri
authors.forename: Sadritdin
authors.initials: S
authors.lastname: Ishmukhamedov
authors.forename: Peter
authors.initials: P
authors.lastname: Covitz
mesh_terms: D035843:Biomedical Research / Q000592:standards; D002986:Clinical Trials as Topic / Q000592:standards* / Q000706:statistics & numerical data; D006801:Humans; D009626:Terminology as Topic; D018875:Vocabulary, Controlled