title: Activity of neutrophil NADPH oxidase in iron-deficient anemia.
abstract: This study was designed to measure the effects of iron supplementation on respiratory burst in iron-deficient anemia. The performance of neutrophils was evaluated by measuring the activity of NADPH oxidase in 18 patients with iron-deficient anemia before and after body iron stores are saturated. The activity of NADPH oxidase was significantly lower in pretreatment patients relative to controls (p<0.05). The activity increased after iron supplementation to levels that had no significant differences relative to controls.
authors.affiliation: Department of Hematology, Medical School, Selcuk University, Konya, Turkey.
authors.forename: Erdal
authors.initials: E
authors.lastname: Kurtoglu
authors.forename: Aysegul
authors.initials: A
authors.lastname: Ugur
authors.forename: Abdulkerim Kasim
authors.initials: AK
authors.lastname: Baltaci
authors.forename: Rasim
authors.initials: R
authors.lastname: Mogolkoc
authors.forename: Levent
authors.initials: L
authors.lastname: Undar
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000201:enzymology* / Q000276:immunology; D001770:Blood Bactericidal Activity / Q000276:immunology; D019587:Dietary Supplements; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000494:pharmacology; D019255:NADPH Oxidases / Q000378:metabolism*; D009504:Neutrophils / Q000201:enzymology*; D010587:Phagocytosis / Q000276:immunology; D013050:Spectrometry, Fluorescence; D018709:Statistics, Nonparametric
chemical_list: D007501:Iron; D019255:NADPH Oxidases