title: [Antimicrobial activity of saponins from Hedera taurica C a r r].
abstract: The antibacterial and antifungal action of saponins Sx1, taurozide H2, taurozide I and their effect on bioluminescent system of photobacteria Photobacterium phosphoreum (Cohn) Ford were investigated. Saponins H2 and I had no antimicrobial effect. Saponin Sx1 possessed antifungal activity in vitro with respect to Candida albicans, C. krusei, C. tropicalis. Saponin Sx1 is less toxic to P. phosphoreum than well-known antiseptics--chlorhexedin and miramistin.
authors.affiliation: Crimea State Medical University, Simferopol.
authors.forename: E G
authors.initials: EG
authors.lastname: Mel'nichenko
authors.forename: M A
authors.initials: MA
authors.lastname: Kirsanova
authors.forename: V I
authors.initials: VI
authors.lastname: Grishkovets
authors.forename: L V
authors.initials: LV
authors.lastname: Tyshkevich
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Krivorutchenko
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D035981:Hedera / Q000737:chemistry*; D008163:Luminescent Measurements; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010776:Photobacterium / Q000187:drug effects / Q000502:physiology; D012503:Saponins / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D012503:Saponins