title: Maxillary bone invasion by gingival carcinoma as an indicator of cervical metastasis.
abstract: OBJECTIVE
  To evaluate the significance of maxillary bone invasion by gingival carcinoma as an indicator of cervical metastasis.
  
  
  METHODS
  Twenty-one patients with squamous cell carcinoma of the upper gingiva were included in the study. The extent of bone invasion was assessed by dental CT. Six patients had cervical metastases at the initial examination and eight more developed them during the 2-year follow-up period. The relationship of cervical metastases with age and gender of these patients, as well as with the size of the lesion and extent of bone invasion, was examined by logistic multivariate regression analysis.
  
  
  RESULTS
  There was a significant relationship between the presence of bone invasion and the presence of cervical metastasis (P<0.05).
  
  
  CONCLUSIONS
  Maxillary bone invasion is an indicator of cervical metastasis in gingival carcinoma.
authors.affiliation: Oral and Maxillofacial Radiology, Graduate School, Tokyo Medical and Dental University, Japan. iogura@mascat.nihon-u.ac.jp
authors.forename: I
authors.initials: I
authors.lastname: Ogura
authors.forename: T
authors.initials: T
authors.lastname: Kurabayashi
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Amagasa
authors.forename: N
authors.initials: N
authors.lastname: Okada
authors.forename: T
authors.initials: T
authors.lastname: Kaneda
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary*; D005260:Female; D005500:Follow-Up Studies; D005887:Gingival Neoplasms / Q000473:pathology*; D006801:Humans; D016015:Logistic Models; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D015999:Multivariate Analysis; D009333:Neck; D009361:Neoplasm Invasiveness; D012737:Sex Factors; D014057:Tomography, X-Ray Computed