title: Clinical and parasitological studies on the efficacy of Mirazid in treatment of schistosomiasis haematobium in Tatoon, Etsa Center, El Fayoum Governorate.
abstract: No doubt, schistosomiasis tops all the endemic parasitic diseases world-wide particularly in Egypt. This study evaluated the efficacy of Mirazid (Commiphora molmol) in the treatment of parasitologically and clinically and ultrasonography confirmed cases of schistosomiasis haematobium in Tatoon village. A sum of 70 out of 885 individuals of both sexes (>15 to 60 years old) screened for S. haematobium infection were selected. They had light infection (1-10 eggs/10 ml.), moderate infection (10-100 eggs/10 ml.) and heavy infection (>100/10 ml.). They were subjected to urine and stool analysis, renal function tests, clinical examination and abdomino-pelvic ultrasound. They were treated with Mirazid as 10 mgm/Kg. However, eight of them were unable to swallow the drug. Out of the 62 schistosomiasis haematobium patients, 57 (91.9%) were cured after two months follow up and the cure rate reached 59 (95.2%) on the 3rd month post-Mirazid treatment. The cure result was evaluated clinically, parasitologically and ultrasonographically. So, Mirazid in a dose of two capsules (600 mgm) on an empty stomach before breakfast for six successive days proved to be very effective and safe in the treatment of schistosomiasis haematobium.
authors.affiliation: Department of Urology, Faculty of Medicine, Ain Shams University, Egypt.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: El Baz
authors.forename: Tosson A
authors.initials: TA
authors.lastname: Morsy
authors.forename: Mahmoud M
authors.initials: MM
authors.lastname: El Bandary
authors.forename: Saad M
authors.initials: SM
authors.lastname: Motawea
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D029744:Commiphora / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D004534:Egypt; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D012548:Schistosoma haematobium / Q000187:drug effects; D012553:Schistosomiasis haematobia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000517:prevention & control; D012556:Schistosomicides / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography; D014556:Urine / Q000469:parasitology
chemical_list: D010936:Plant Extracts; D012556:Schistosomicides