Lack of plasma leptin response to feeding in newborn infants.
OBJECTIVE
Previous reports of the postprandial regulation of leptin are controversial, and there have been few studies on the effects of breast-feeding on postprandial regulation in newborn infants. We examined the response of plasma leptin to breast- and formula-feeding in newborn infants.


METHODS
We measured the plasma leptin levels using an enzyme-linked immunosorbent assay kit before and after feeding in 12 breast-fed and 11 formula-fed mature infants.


RESULTS
There was no significant difference in plasma leptin levels in breast-fed infants before and after feeding or in artificially fed infants before and after feeding.


CONCLUSIONS
Our results suggest that feeding does not play a role in the acute response of circulating leptin levels in either breast- or formula-fed infants.
Shimizu
T
T
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan. tsimizut@aol.com
Satoh
Y
Y
Shoji
H
H
Hisata
K
K
Tadokoro
R
R
Shinohara
K
K
Shiga
S
S
Yamashiro
Y
Y
D001942:Breast Feeding; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005526:Food, Formulated; D006801:Humans; D007231:Infant, Newborn; D020738:Leptin / Q000097:blood*; D008297:Male; D013997:Time Factors
D020738:Leptin