Hyperglycaemia and cardiovascular risk.
Cardiovascular diseases represent, today, the principal cause of mortality in the general population, especially in subjects with type 2 diabetes mellitus. In these patients the risk of death from cardiovascular diseases is equal to that of non-diabetic subjects with a previous episode of myocardial infarction. Many factors concur to determine such high risk. Hyperglycaemia contributes to the increase in morbidity and cardiovascular mortality associated with diabetes mellitus. Hyperglycaemia acts as a multiplier of cardiovascular risk due to frequent association of multiple risk factors in diabetic patients. Therefore, effective treatment requires a more complete assessment of quantitative and qualitative aspects of glycemic control as well as all components of the diabetic syndrome or, more commonly, metabolic syndrome.
Palumbo
F
F
Department of Endocrinology and Metabolism, Cisanello Hospital, Via Paradisa 2, I-56124, Pisa, Italy.
Bianchi
C
C
Miccoli
R
R
Del Prato
S
S
D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000401:mortality; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006943:Hyperglycemia / Q000150:complications*; D009017:Morbidity; D012306:Risk; D012307:Risk Factors; D016019:Survival Analysis
D015415:Biomarkers; D001786:Blood Glucose; D006442:Glycated Hemoglobin