Colloidal stable silica encapsulated nano-magnetic composite as a novel bio-catalyst carrier.
A colloidal stable silica-encapsulated magnetic nano-composite of a controlled dimension is, for the first time, employed to carry beta-lactamase via chemical linkage on the silica overlayer: activity study reflects that this new type of immobilisation allows site (enzyme) isolation, accessibility as good as free enzyme and recovery & reusability upon application of magnetic separation.
Gao
Xin
X
Surface and Catalysis Research Centre, School of Chemistry, University of Reading, Reading, UK RG6 6AD.
Yu
K M Kerry
KM
Tam
Kin Y
KY
Tsang
Shik Chi
SC
D001709:Biotechnology; D003102:Colloids / Q000737:chemistry*; D004795:Enzyme Stability; D004800:Enzymes, Immobilized / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D007700:Kinetics; D008280:Magnetics; D008832:Microchemistry; D008855:Microscopy, Electron, Scanning; D012822:Silicon Dioxide / Q000737:chemistry*; D001618:beta-Lactamases / Q000737:chemistry*
D003102:Colloids; D004800:Enzymes, Immobilized; D005290:Ferric Compounds; C000499:ferric oxide; D012822:Silicon Dioxide; D001618:beta-Lactamases