title: Computational prediction of transcription-factor binding site locations.
abstract: Identifying genomic locations of transcription-factor binding sites, particularly in higher eukaryotic genomes, has been an enormous challenge. Various experimental and computational approaches have been used to detect these sites; methods involving computational comparisons of related genomes have been particularly successful.
authors.affiliation: Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. mlbulyk@rascal.med.harvard.edu
authors.forename: Martha L
authors.initials: ML
authors.lastname: Bulyk
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D002874:Chromosome Mapping / Q000379:methods*; D019295:Computational Biology / Q000379:methods* / Q000706:statistics & numerical data; D004271:DNA, Fungal / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D011237:Predictive Value of Tests; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D014157:Transcription Factors