title: TT virus-positive hepatocellular carcinoma arising from non-cirrhotic liver in an elderly man.
abstract: A 43-mm hepatic tumor was incidentally detected by computed tomography in a 72-year-old man. Liver function test results were normal. Serum hepatitis B, C and G viruses were negative, while serum TT virus was positive. Autoantibodies were negative. The patient had no history of alcohol consumption. The tumor was found to be a moderately differentiated hepatocellular carcinoma (HCC) from a resected specimen. Neither lobular inflammation nor fibrosis was observed in the surrounding liver. Intrahepatic hepatitis B virus was not detected. This is a case of non-B, non-C HCC positive for only TT virus arising from a non-cirrhotic liver.
authors.affiliation: Department of Internal Medicine, Ako Central Hospital, Ako.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Toshikuni
authors.forename: Kouichi
authors.initials: K
authors.lastname: Kayano
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nishioka
authors.forename: Mikio
authors.initials: M
authors.lastname: Mitsunaga
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Omoto
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Nagao
authors.forename: Motohisa
authors.initials: M
authors.lastname: Kojo
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology*; D004266:DNA Virus Infections / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology*; D008297:Male; D036542:Tomography, Spiral Computed; D022783:Torque teno virus