title: [Two resected cases of advanced gastric cancer with peritoneal dissemination after successful treatment with TS-1 plus low-dose CDDP].
abstract: We report two resected cases of advanced gastric cancer with peritoneal dissemination after successful treatment with TS-1 plus low-dose CDDP. Patient 1 presented with right hypochondralgia and underwent laparotomy with diagnosis of type 4 gastric cancer by gastrointestinal fiberscopy. However, the tumor was judged to be unresectable due to peritoneal dissemination, and chemotherapy was performed. At the completion of course 1, he underwent laparotomy again. Although the tumor involved the body of the pancreas and transverse colon, there was no peritoneal dissemination. Therefore, a total gastrectomy was performed with distal pancreatectomy, partial colectomy, cholecystectomy, and D2 lymph node dissection. Patient 2 presented with anorexia and was diagnosed with type 3 gastric cancer by gastrointestinal fiberscopy. CT revealed the tumor was unresectable due to peritoneal dissemination, and so chemotherapy was performed. He underwent laparotomy at the completion of course 3. There was no peritoneal dissemination, so a total gastrectomy was performed with cholecystectomy and D2 lymph node dissection. Both patients remain alive and in good condition without any signs of recurrence after surgery.
authors.affiliation: Dept. of Surgery, Kochi Municipal Central Hospital.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Shima
authors.forename: Tadashi
authors.initials: T
authors.lastname: Horimi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Nishioka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Okabayashi
authors.forename: Madoka
authors.initials: M
authors.lastname: Hamada
authors.forename: Tadanori
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shibuya
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Sakurama
authors.forename: Manabu
authors.initials: M
authors.lastname: Nishie
authors.forename: Jun
authors.initials: J
authors.lastname: Iwata
authors.forename: Akihito
authors.initials: A
authors.lastname: Tsuji
authors.forename: Sojiro
authors.initials: S
authors.lastname: Morita
mesh_terms: D000368:Aged; D000855:Anorexia / Q000139:chemically induced; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin