title: Neonate with a fibrosarcoma and consumptive coagulopathy.
abstract: We report a case of a neonate with a congenital tumor on the left palm. The patient had a grapefruit-sized tumor and coagulopathy at birth and was presumed to have a hemangioendothelioma with associated Kasabach-Merritt phenomenon. When the tumor failed to respond to systemic steroids, a biopsy specimen was taken, revealing a fibrosarcoma. We describe this case to highlight the importance of including rare tumors, such as fibrosarcomas, in the clinical differential when evaluating a congenital tumor with associated coagulopathy. We discuss subtle differences in clinical presentations that might aid in differentiating vascular tumors from fibrosarcomas.
authors.affiliation: Division of Dermatology, Department of Pediatrics, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, USA.
authors.forename: Maryam
authors.initials: M
authors.lastname: Asgari
authors.forename: Brian P
authors.initials: BP
authors.lastname: Rubin
authors.forename: Robin L
authors.initials: RL
authors.lastname: Hornung
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000150:complications / Q000151:congenital / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D005354:Fibrosarcoma / Q000150:complications / Q000151:congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006225:Hand; D006801:Humans; D007231:Infant, Newborn; D012878:Skin Neoplasms / Q000150:complications / Q000151:congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D016038:Skin Transplantation
chemical_list: D000305:Adrenal Cortex Hormones