title: Aminopeptidase A, generating one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, plays a key role in central control of blood pressure.
authors.affiliation: INSERM U 36, College de France, 11 place Marcelin Berthelot, 75005 Paris, France.
authors.forename: Raphael
authors.initials: R
authors.lastname: Rozenfeld
authors.forename: Annabelle
authors.initials: A
authors.lastname: Reaux
authors.forename: Xavier
authors.initials: X
authors.lastname: Iturrioz
authors.forename: Celine
authors.initials: C
authors.lastname: Fassot
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Fournie-Zaluski
authors.forename: Christelle
authors.initials: C
authors.lastname: David
authors.forename: Bernard
authors.initials: B
authors.lastname: Maigret
authors.forename: Bernard Pierre
authors.initials: BP
authors.lastname: Roques
authors.forename: Pierre
authors.initials: P
authors.lastname: Corvol
authors.forename: Catherine
authors.initials: C
authors.lastname: Llorens-Cortes
mesh_terms: D000804:Angiotensin II / Q000502:physiology; D000805:Angiotensin III / Q000096:biosynthesis / Q000502:physiology*; D000818:Animals; D001665:Binding Sites; D001794:Blood Pressure / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D018826:CD13 Antigens / Q000037:antagonists & inhibitors; D018360:Crystallography, X-Ray; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000494:pharmacology; D043384:Glutamyl Aminopeptidase / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008297:Male; D008715:Methionine / Q000031:analogs & derivatives* / Q000494:pharmacology; D051379:Mice; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D012084:Renin-Angiotensin System / Q000502:physiology*; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013451:Sulfonic Acids / Q000494:pharmacology
chemical_list: C472311:2-amino-4-methylsulfonyl butane thiol; C101968:EC 33; D004791:Enzyme Inhibitors; D013438:Sulfhydryl Compounds; D013451:Sulfonic Acids; D000804:Angiotensin II; D000805:Angiotensin III; C101969:EC 27; D008715:Methionine; D018826:CD13 Antigens; D043384:Glutamyl Aminopeptidase