Are caveolae involved in clathrin-independent endocytosis?
In addition to endocytosing molecules via clathrin-coated pits, cells also internalize membrane and fluid by a clathrin-independent endocytic mechanism. In this article we search for the equivalent of clathrin-coated pits in clathrin-independent endocytosis, and discuss some pitfalls in the interpretation of electron micrographs. We also discuss how the early steps in clathrin-independent endocytosis might be analysed morphologically, and we argue that caveolae are not involved in clathrin-independent endocytosis.
van Deurs
B
B
Structure Cell Biology Unit, Department of Anatomy, the Panum Institute, University of Copenhagen, Denmark.
Holm
P K
PK
Sandvig
K
K
Hansen
S H
SH