title: Primary cutaneous B-cell lymphomas: a practical approach.
abstract: PCBCL are a heterogeneous group of B-cell lymphomas that originate in the skin, with the absence of extracutaneous disease at diagnosis. Overall, these cutaneous lymphomas have an excellent prognosis. Recurrences are common but dissemination is rare. The EORTC classification allows a more uniform diagnosis and treatment of patients with PCBCL. Careful clinical and pathologic correlation is critical in confirming a diagnosis of PCBCL, before deciding on therapy. Several therapeutic options that are aimed at cure, are available. In most instances, chemotherapy should not be the first line of treatment.
authors.affiliation: Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA. mariefrance.demierre@bmc.org
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Demierre
authors.forename: Helmut
authors.initials: H
authors.lastname: Kerl
authors.forename: Rein
authors.initials: R
authors.lastname: Willemze
mesh_terms: D000465:Algorithms; D003131:Combined Modality Therapy; D006801:Humans; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D011379:Prognosis; D012878:Skin Neoplasms / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D015996:Survival Rate