title: [Inhibitory effect of antimicrobial preparation from lipids of marine fishes on tissue and microbial enzymes].
abstract: We obtained a new food preservative from marine fish lipids possessing pronounced activity in relation to bacteria and microscopic fungi. The effects of this preparation on enzymes of microorganisms and muscle tissue of marine hydrobionts were studied. In vitro the preparation irreversibly inhibited acid and alkaline proteases and proteolytic and lipolytic enzymes of microorganisms and reduced enzyme activity in fish muscle tissue. The inhibitory effect of this preparation on enzymes contributes to stabilization of hydrolytic processes in meat of hydrobionts and suppresses microorganism growth in storage.
authors.affiliation: Pacific Research Fisheries Center (TINRO-Center), Vladivostok, 690950 Russia.
authors.forename: T A
authors.initials: TA
authors.lastname: Davletshina
authors.forename: L V
authors.initials: LV
authors.lastname: Shul'gina
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Lazhentseva
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Blinov
authors.forename: T N
authors.initials: TN
authors.lastname: Pivnenko
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000032:analysis; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D005399:Fishes / Q000378:metabolism; D005520:Food Preservatives / Q000737:chemistry / Q000494:pharmacology; D018093:Gelatinases / Q000032:analysis; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry*; D008666:Metalloendopeptidases / Q000032:analysis; D003904:Mitosporic Fungi / Q000187:drug effects*; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000201:enzymology; D009792:Oceans and Seas; D010447:Peptide Hydrolases / Q000032:analysis; D010740:Phospholipases / Q000032:analysis
chemical_list: D000890:Anti-Infective Agents; D004791:Enzyme Inhibitors; D005520:Food Preservatives; D008055:Lipids; D010740:Phospholipases; D010450:Endopeptidases; D010447:Peptide Hydrolases; D018093:Gelatinases; D008666:Metalloendopeptidases; C030895:caseinase