Congo red, doxycycline, and HSP70 overexpression reduce aggregate formation and cell death in cell models of oculopharyngeal muscular dystrophy.
Bao
Y P
YP
Sarkar
S
S
Uyama
E
E
Rubinsztein
D C
DC
D000328:Adult; D000818:Animals; D019556:COS Cells / Q000737:chemistry / Q000378:metabolism; D016923:Cell Death / Q000187:drug effects / Q000235:genetics; D002460:Cell Line; D002522:Chlorocebus aethiops; D003224:Congo Red / Q000737:chemistry*; D004318:Doxycycline / Q000494:pharmacology*; D005260:Female; D018840:HSP70 Heat-Shock Proteins / Q000096:biosynthesis* / Q000276:immunology; D006801:Humans; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D039141:Muscular Dystrophy, Oculopharyngeal / Q000235:genetics* / Q000378:metabolism; D010609:Pharyngeal Muscles / Q000737:chemistry / Q000378:metabolism; D039103:Poly(A)-Binding Protein II / Q000032:analysis / Q000235:genetics / Q000276:immunology
D018840:HSP70 Heat-Shock Proteins; D039103:Poly(A)-Binding Protein II; D003224:Congo Red; D004318:Doxycycline