title: Fatal leptospirosis presenting as musculoskeletal chest pain.
abstract: After holidaying in Vanuatu, a 24-year-old man presented with pleuritic chest pain and chest wall tenderness thought to be musculoskeletal in origin. He developed fatal acute renal failure, jaundice, respiratory failure, myocarditis and rhabdomyolysis. Subsequent serological results showed a rise in serum titre of antibodies to Leptospira grippotyphosa, from 1 : 50 to 1 : 800, consistent with acute infection.
authors.affiliation: Intensive Care Unit, PO Box 626, Castle Hill, NSW 1765, Australia. fmoleary@bigpond.com
authors.forename: Fenton M
authors.initials: FM
authors.lastname: O'Leary
authors.forename: Jaspal S
authors.initials: JS
authors.lastname: Hunjan
authors.forename: Ross
authors.initials: R
authors.lastname: Bradbury
authors.forename: Govindasamy
authors.initials: G
authors.lastname: Thanakrishnan
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007919:Leptospira / Q000276:immunology; D007922:Leptospirosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology; D009140:Musculoskeletal Diseases / Q000150:complications / Q000175:diagnosis*; D010998:Pleurisy / Q000150:complications; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000175:diagnosis
chemical_list: D000907:Antibodies, Bacterial