[The effect of surface phenomena on the processing of solid materials. II. Experimental evaluation of surface phenomena of solid materials].
The functions of friction and adhesion in the processing of solid materials were evaluated in our work. The second part of our study dealt with some practical examples from our practice. Indomethacin was used for the examination of adhesion, dimenhydrinate for the study of friction, and metronidazole for the determination of the spreading coefficient. Several technological methods (coating, granulation, pelletization and tableting) were used. The positive effects of the processes on the various phenomena (surface free energy, adhesion force and spreading coefficient) were emphasized. The influences of alteration in the parameters on the flowability, compressibility, compact texture, etc. were assessed.
Tüske
Zsófia
Z
Szegedi Tudományegyetem, Gyógyszertechnológiai Intézet, Szeged, Eötvös u. 6.-6723.
Bajdik
János
J
Hódi
Klára
K
Erös
István
I
D003460:Crystallization; D008795:Metronidazole / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D013499:Surface Properties; D013816:Thermodynamics
D004364:Pharmaceutical Preparations; D008795:Metronidazole