[Coeliac disease--new clinical findings and diagnostic tools].
Coeliac disease is a disorder characterised by intolerance to wheat gluten and related proteins from rye and barley, ingestion of which leads to a harmful immune activation in the small intestinal mucosa. The symptoms are often vague and do not suggest an intestinal disorder. The diagnosis is often easy once the question is raised; it requires a combination of serological tests and small intestinal biopsies. Coeliac disease can also exist with a normal serology. The trend in many countries is to require less pronounced mucosal abnormalities than previously for the diagnosis.
Lundin
Knut E A
KE
Medisinsk avdeling, Rikshospitlet, Oslo. knut.lundin@rikshospitalet.no
Farstad
Inger Nina
IN
Sollid
Ludvig M
LM
D000906:Antibodies / Q000032:analysis; D002446:Celiac Disease / Q000175:diagnosis* / Q000178:diet therapy / Q000276:immunology / Q000473:pathology; D004386:Duodenum / Q000473:pathology; D005903:Gliadin / Q000276:immunology; D005983:Glutens / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D012698:Serologic Tests
D000906:Antibodies; D006680:HLA Antigens; D005983:Glutens; D005903:Gliadin