title: Total knee arthroplasty in hemophilic arthropathy.
abstract: Total knee arthroplasty (TKA) is very effective in relieving pain and improving function in patients with advanced hemophilic arthropathy. Because of intra-articular fibrosis and extra-articular muscle contracture, the gain in motion after TKA has been unsatisfactory. The purpose of this study is to report the results of TKA in patients with hemophilia using posterior cruciate ligament (PCL)-sacrificing prostheses. From April 1987 to May 1998, 9 patients underwent 14 PCL-sacrificing TKAs for advanced hemophilic arthropathy. The average length of follow-up evaluation in surviving patients (13 knees) was 77 months (range, 25-159). A statistically significant difference was found between the preoperative and postoperative values with respect to pain score (5 vs 48), functional score (42 vs 78), flexion deformity (17 degrees vs 5 degrees ), and flexion range (56 degrees vs 81 degrees ). Nine complications occurred in 6 knees. One patient died from HIV-related complications, and none of the patients seroconverted to HIV during the follow-up period.
authors.affiliation: Department of Orthopaedic Surgery, University of Texas-Houston Health Science Center, 77030, USA.
authors.forename: Dhiren S
authors.initials: DS
authors.lastname: Sheth
authors.forename: Donna
authors.initials: D
authors.lastname: Oldfield
authors.forename: Catherine
authors.initials: C
authors.lastname: Ambrose
authors.forename: Terry
authors.initials: T
authors.lastname: Clyburn
mesh_terms: D000328:Adult; D019645:Arthroplasty, Replacement, Knee; D001843:Bone Cements; D005500:Follow-Up Studies; D006395:Hemarthrosis / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications; D002836:Hemophilia B / Q000150:complications; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D007720:Knee Prosthesis; D008297:Male; D010147:Pain Measurement; D016119:Posterior Cruciate Ligament / Q000601:surgery; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D013997:Time Factors
chemical_list: D001843:Bone Cements