[Paraneoplastic opsoclonus-myoclonus syndrome associated with small-cell lung cancer].
Opsoclonus-myoclonus syndrome was observed in a patient treated for small-cell lung cancer. Opsoclonus presented as anarchic involuntary eye movements associated with myoclonies of the limbs and trunk. Opsoclonus-myoclonus is exceptional and a specific expression among several paraneoplastic manifestations described in small-cell lung cancer. These manifestations develop late after diagnosis of cancer. Presence of anti-neuronal antibodies in the serum (inconstant) is a factor of very poor prognosis.
Margery
J
J
Unité Fonctionnelle d'Oncologie Pulmonaire, Service de Pneumologie (Pr C. Mayaud), Hôpital Tenon, 4, rue de la Chine, 75020 Paris. j.margery@wanadoo.fr
Ferroir
J-P
JP
Epaud
C
C
Martin
C
C
Milleron
B
B
D000368:Aged; D018288:Carcinoma, Small Cell / Q000150:complications*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D020361:Paraneoplastic Syndromes, Nervous System / Q000209:etiology*