title: Increase in serum S100B protein level after a swimming race.
abstract: Physical activity has been shown to be a beneficial stimulus to the central and peripheral nervous systems. The S100B is a cytokine physiologically produced and released predominantly by astrocytes on the central nervous system (CNS). In order to study the possible influence of a nonimpact exercise on S100B serum levels, we measured this protein serum level after a 7,600-meter swimming race. We observed an increase in S100B levels in athletes post-race compared with their baseline values, pointing to a potential acute influence of physical exercise on serum S100B levels not related with CNS injury. We discuss this result and emphasize the possible central and peripheral origins of S100B serum levels.
authors.affiliation: Dept. de Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Marcelo O
authors.initials: MO
authors.lastname: Dietrich
authors.forename: Adriano B
authors.initials: AB
authors.lastname: Tort
authors.forename: Débora V
authors.initials: DV
authors.lastname: Schaf
authors.forename: Marcelo
authors.initials: M
authors.lastname: Farina
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Gonçalves
authors.forename: Diogo O
authors.initials: DO
authors.lastname: Souza
authors.forename: Luis V
authors.initials: LV
authors.lastname: Portela
mesh_terms: D000293:Adolescent; D000328:Adult; D001324:Autoantigens / Q000097:blood*; D006801:Humans; D008297:Male; D009414:Nerve Growth Factors / Q000097:blood*; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood*; D013550:Swimming / Q000502:physiology*
chemical_list: D001324:Autoantigens; D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; C579160:S100B protein, human