Clinical trials for pulmonary metastasectomy.
There remains great controversy as to the indications and true benefits for pulmonary metastasectomy. The number of metastatic lesions, length of disease-free interval, and unilaterality has shown to be important prognostic factors on overall survival. In this review, we evaluate a number of clinical trials and critically assess the rational to perform pulmonary metastasectomy, which is a local treatment for a systemic disease process.
Patel
Amit N
AN
Section of Thoracic Surgery, University of Pittsburgh Medical Center, PA 15213, USA.
Lamb
Jason
J
Patel
Nilesh
N
Santos
Ricardo S
RS
Stavropoulos
Christos
C
Landreneau
Rodney J
RJ
D014408:Biomarkers, Tumor / Q000032:analysis; D002986:Clinical Trials as Topic; D018572:Disease-Free Survival; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D011013:Pneumonectomy
D014408:Biomarkers, Tumor