Molecular biology of the human immunodeficiency virus: current and future targets for intervention.
Inhibitors of the reverse transcriptase and protease enzymes of the human immunodeficiency virus form the backbone of current antiretroviral therapy. However, other therapeutic targets have been identified in studies of interactions between HIV and its target cells. This review presents an overview of HIV replication, emphasizing recently recognized cellular and viral molecules that may be exploited in future pharmacological approaches to prevent and treat infection with HIV.
Krogstad
Paul
P
Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. pkrogstad@mednet.ucla.edu
D019380:Anti-HIV Agents / Q000494:pharmacology*; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology*; D015497:HIV-1 / Q000502:physiology*; D006801:Humans
D019380:Anti-HIV Agents