Ablation of symptomatic cysts using absolute ethanol in 11 patients with autosomal-dominant polycystic kidney disease.
OBJECTIVE
To evaluate the effects of cyst ablation with absolute ethanol in autosomal-dominant polycystic kidney disease (ADPKD) patients with symptomatic cysts.


METHODS
Using absolute ethanol, cyst ablation was performed in 11 patients with documented ADPKD who suffered cyst pain refractory to medical treatment. An ethanol solution was instilled into the largest symptomatic cysts through a catheter. We assessed the therapeutic efficacy of the procedure by tracking subjective pain relief during a 3 to 24-month follow-up period after ablation.


RESULTS
At follow-up, we found that the duration of subjective pain relief was 12 to 24 months in seven patients, 4 to 11 months in one, and less than 3 months in three.


CONCLUSIONS
Selective ablation of a symptomatic cyst may be a valid option in managing chronic pain caused by one or a few large cysts in ADPKD patients.
Lee
Young Rae
YR
Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. lesiles@chollian.net
Lee
Kyu-Beck
KB
D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010148:Intractable Pain / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D010166:Palliative Care / Q000379:methods; D016891:Polycystic Kidney, Autosomal Dominant / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D015911:Sclerotherapy / Q000379:methods*; D012997:Solvents / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D003287:Contrast Media; D012997:Solvents; D000431:Ethanol