[Mandibular fracture fixed with PDLLA/nano-HA compound plates: an animal study].
OBJECTIVE
To investigate the applicability of PDLLA/nano-HA compound plates used in internal fixation of mandibular fractures.


METHODS
Rabbit mandibular fracture model was used in this study. Clinical observation, the amount of callus, histological observation were studied and compared with PDLLA plates.


RESULTS
All fractures were fixed rigidly. There was 1 animal experienced local inflammation and then forming fistula in the side of PDLLA plate at postoperative 2 and 3 weeks. No side-effects were found in the side of compound plates. During the early stage of bone healing, the quality of callus in the side of compound plates was apparently more than that in the other side, and histological study showed that the osteoblasts and fibroblasts were more active in the side of compound plate in the early healing stage.


CONCLUSIONS
PDLLA/nano-HA compound plate has a proper degradation time. Compared with PDLLA plates, it is more effective and safer when used in mandibular fracture.
Hu
Tu-qiang
TQ
Department of Stomatology, Shiyan People's Hospital, Shiyan, Hubei 442000, China.
Li
Zu-bing
ZB
Wan
Tao
T
Li
Shi-pu
SP
Yan
Yu-hua
YH
D000818:Animals; D001860:Bone Plates; D017886:Durapatite; D005593:Fracture Fixation, Internal / Q000379:methods*; D008297:Male; D008337:Mandibular Fractures / Q000601:surgery*; D011091:Polyesters; D011817:Rabbits
D011091:Polyesters; C033616:poly(lactide); D017886:Durapatite