Tandem RCM of dienynes for the construction of taxol-type carbocyclic systems.
[reaction: see text] Tandem ring-closing metathesis of hydrindanone dienynes allows access to taxosteroids, a new class of compounds that combine the [5.3.1] carbocyclic system of taxanes with rings C and D of the steroid skeleton.
Garcia-Fandiño
Rebeca
R
Departamento de Química Orgánica e Unidade Asociada ó CSIC, Facultade de Química, Universidade de Santiago, 15706 Santiago de Compostela, Spain.
Codesido
Eva M
EM
Sobarzo-Sánchez
Eduardo
E
Castedo
Luis
L
Granja
Juan R
JR