A successful pregnancy after intracytoplasmic sperm injection and embryo transfer in a patient with endometrial cancer who was treated conservatively.
OBJECTIVE
To describe a patient with polycystic ovary syndrome (PCOS) conceiving with intracytoplasmic sperm injection (ICSI) and embryo transfer after conservative treatment of early stage endometrial cancer.


METHODS
Case report.


METHODS
Tertiary center for assisted reproductive technologies.A 32-year-old woman with PCOS, primary infertility of 4 years duration, and grade 1 endometrioid endometrial cancer.


METHODS
Assessment of myometrial invasion and extrauterine spread with magnetic resonance imaging (MRI) and explorative laparotomy. High-dose progestin treatment and ICSI and embryo transfer.


METHODS
Successful take-home baby and no residual endometrial cancer.


RESULTS
A healthy normal female infant with a birth weight of 1740 g was born by cesarean section at 30 weeks' gestation. No residual cancer was detected at the follow-up curettage performed 2 months after the delivery.


CONCLUSIONS
Conservative uterus-preserving treatment may be considered in patients with early stage endometrial cancer. Assisted reproductive technologies may be used in such patients for immediate achievement of pregnancy.
Yarali
Hakan
H
Department of Obstetrics and Gynecology, Hacettepe University, School of Medicine, Ankara, Turkey. hyarali@hacettepe.edu.tr
Bozdag
Gurkan
G
Aksu
Tarik
T
Ayhan
Ali
A
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D002585:Cesarean Section; D004624:Embryo Transfer; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D017258:Medroxyprogesterone Acetate / Q000627:therapeutic use; D019290:Megestrol Acetate / Q000627:therapeutic use; D011247:Pregnancy; D011256:Pregnancy Outcome; D011374:Progesterone / Q000627:therapeutic use; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D014463:Ultrasonography
D018931:Antineoplastic Agents, Hormonal; D011374:Progesterone; D017258:Medroxyprogesterone Acetate; D019290:Megestrol Acetate