Acception of cholesterol from cells in men of the Russian population correlates with concentration of pre-beta1 high-density lipoproteins.
We analyzed subfraction composition of HDL and cholesterol-acceptor properties of the plasma in Russian men with high and low HDL cholesterol. HDL were subfractionated by two-dimensional electrophoresis in agarose-polyacrylamide gel. The content of pre-beta1 HDL increased in individuals with high concentration of HDL cholesterol and strictly correlated with acception of cellular cholesterol in both groups.
Serdyuk
A P
AP
Department of Metabolic Disorders, State Research Center for Preventive Medicine, Russian Ministry of Health, Moscow. vicamet@orc.ru
Lasselin
K
K
Castro
G
G
Litinskaya
O A
OA
Frushar
G
G
Metel'skaya
V A
VA
D000818:Animals; D016632:Apolipoprotein A-I / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000737:chemistry; D045744:Cell Line, Tumor; D005591:Chemical Fractionation; D002784:Cholesterol / Q000097:blood / Q000737:chemistry / Q000378:metabolism*; D008076:Cholesterol, HDL / Q000097:blood* / Q000737:chemistry* / Q000302:isolation & purification; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood; D051381:Rats; D012426:Russia / Q000453:epidemiology; D014280:Triglycerides / Q000097:blood
D016632:Apolipoprotein A-I; D008076:Cholesterol, HDL; D014280:Triglycerides; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase