title: Doege-Potter syndrome: hypoglycemia associated with malignant solitary fibrous tumor.
abstract: We report a case of recurrent solitary fibrous tumor with associated hypoglycemia, the "Doege-Potter syndrome." These are rare tumors with a 12-13% rate of malignancy. The syndrome of hypoglycemia is seen in less than 5% of the cases, and the associated tumors are large with a high mitotic rate. The cause of hypoglycemia is related to insulin-like growth factors produced by these tumors. Resection in many cases is curable with resolution of the hypoglycemia. We discuss the different signs and symptoms and literature evidence of treatment options and follow-up.
authors.affiliation: Division of Medical Oncology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. thezafs@aol.com
authors.forename: Haider
authors.initials: H
authors.lastname: Zafar
authors.forename: Chris H
authors.initials: CH
authors.lastname: Takimoto
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Weiss
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications* / Q000209:etiology; D018218:Neoplasms, Fibrous Tissue / Q000150:complications* / Q000503:physiopathology; D013002:Somatomedins / Q000096:biosynthesis*; D013577:Syndrome
chemical_list: D013002:Somatomedins