title: Timing of alcohol and smoking cessation (TASC): smoking among substance use patients screened and enrolled in a clinical trial.
abstract: Tobacco dependence is prevalent among alcohol dependent patients, and causes increased morbidity and mortality. Concurrent treatment for these disorders may be advantageous, but there are concerns about adverse effects on alcohol treatment outcomes. The Timing of Alcohol and Smoking Cessation (TASC) Study is a randomized controlled clinical trial to compare the effectiveness of smoking cessation treatment offered concurrently or six months following intensive rehabilitation for alcohol dependence. This paper describes the study design and baseline characteristics of the study population. Participants were current smokers in intensive alcohol dependence treatment, with willingness to consider quitting smoking. Smoking intervention offered behavioral and pharmacological treatment. One thousand nine hundred forty-three patients were screened for enrollment; 499 were eligible and participated (26%). We describe demographic characteristics, smoking behavior and attitudes among participants and nonparticipants toward smoking cessation and drinking. We conclude that there is considerable interest in smoking cessation in alcohol dependent treatment populations, and recruitment to research studies is feasible.
authors.affiliation: Center for Chronic Disease Outcomes Research, Minneapolis VA Medical Center, and the University of Minnesota, Minneapolis, MN, USA. Anne.M.Joseph@med.va.gov
authors.forename: Anne M
authors.initials: AM
authors.lastname: Joseph
authors.forename: David B
authors.initials: DB
authors.lastname: Nelson
authors.forename: Sean M
authors.initials: SM
authors.lastname: Nugent
authors.forename: Mark L
authors.initials: ML
authors.lastname: Willenbring
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D019973:Alcohol-Related Disorders / Q000150:complications / Q000628:therapy*; D001521:Behavior Therapy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008910:Minnesota; D009538:Nicotine / Q000627:therapeutic use; D016540:Smoking Cessation / Q000379:methods*; D016320:Substance Abuse Treatment Centers; D013997:Time Factors; D014029:Tobacco Use Disorder / Q000150:complications / Q000628:therapy*
chemical_list: D009538:Nicotine