Interactions between GPI-anchored proteins and membrane lipids.
Proteins anchored in membranes by glycosylphosphatidylinositol (GPI) are widely distributed, but the function of this unusual anchor is a puzzle. Recent evidence shows that these proteins can associate with membrane lipids in special ways. One function of GPI anchorage may be to allow proteins to interact with specialized membrane domains.
Brown
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Department of Biochemistry and Cell Biology, SUNY at Stony Brook, Stony Brook, NY 11794, USA.