An unusual cause of acute respiratory distress in a patient with AIDS: primary infection with Toxoplasma gondii.
Hypoxemic pneumonia in AIDS patients is mainly caused by Pneumocystis carinii, Toxoplasma gondii and CMV, although the significance of CMV recovery in BALF is often unclear. Since lung involvement generally occurs during reactivation, T. gondii is not expected to be demonstrated in patients without evidence of past infection with this agent. We report a fatal case of pneumonia revealing a T. gondii primary infection diagnosed thanks to the PCR analysis of the BALF.
Charles
Pierre Emmanuel
PE
Service de Reanimation Médicale, Dijon University Hospital, Dijon, France. pierre-emmanuel.charles@chu-dijon.fr
Doise
Jean Marc
JM
Quenot
Jean Pierre
JP
Aube
Herve
H
Dalle
Frederic
F
Bour
Jean Baptiste
JB
Chavanet
Pascal
P
Blettery
Bernard
B
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000818:Animals; D018450:Disease Progression; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D012128:Respiratory Distress Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D012720:Severity of Illness Index; D014122:Toxoplasma / Q000302:isolation & purification*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy