title: Iris-sutured posterior chamber intraocular lens implantation during penetrating keratoplasty.
abstract: OBJECTIVE
  To evaluate the clinical indications and postoperative results of iris-sutured posterior chamber intraocular lens implants performed during penetrating keratoplasty.
  
  
  METHODS
  Medical records were retrospectively reviewed for preoperative indications and postoperative results of 342 consecutive patients (366 eyes) who underwent iris suturing of a posterior chamber intraocular lens implant during penetrating keratoplasty over a 9-year period.
  
  
  RESULTS
  Mean follow-up was 36 months. The principal indications for corneal transplantation were pseudophakic and aphakic bullous keratopathy. Mean postoperative best spectacle-corrected visual acuity was better than preoperatively at all measured time points (P < 0.0001) and improved from 20/474 preoperatively to 20/85 at 1 year. Nine eyes (7.7%) with known preoperative glaucoma required escalation of therapy by medication or surgery to control the intraocular pressure. Seventy-two eyes (29%) without known preoperative glaucoma required treatment of elevated intraocular pressure. Seventy-nine eyes (28%) without known preoperative cystoid macular edema were additionally diagnosed. Mean endothelial cell counts declined throughout the study time frame. Corneal donor rejection episodes occurred in 36 (9.8%) eyes, with the majority having a single episode. Overall, 27 (7.4%) eyes had known graft failure at last follow-up. Two eyes (0.5%) were enucleated following wound disruption.
  
  
  CONCLUSIONS
  These long-term results of iris-sutured posterior chamber intraocular lens implants performed during penetrating keratoplasty suggest acceptable visual acuity, graft survival, and complication rates. They are similar to published retrospective and prospective results of flexible open-loop anterior chamber and transsclerally-sutured posterior chamber intraocular lens implants placed during penetrating keratoplasty.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, IA, USA. afarjo@umich.edu
authors.forename: Ayad A
authors.initials: AA
authors.lastname: Farjo
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Rhee
authors.forename: H Kaz
authors.initials: HK
authors.lastname: Soong
authors.forename: Roger F
authors.initials: RF
authors.lastname: Meyer
authors.forename: Alan
authors.initials: A
authors.lastname: Sugar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D005901:Glaucoma / Q000209:etiology / Q000503:physiopathology; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007498:Iris / Q000601:surgery*; D015948:Keratoplasty, Penetrating; D019654:Lens Implantation, Intraocular / Q000009:adverse effects / Q000379:methods*; D008268:Macular Degeneration / Q000209:etiology; D008269:Macular Edema / Q000209:etiology; D008875:Middle Aged; D012189:Retrospective Studies; D013537:Sutures; D014792:Visual Acuity