Flagellar regeneration in Chlamydomonas: a model system for studying organelle assembly.
How do the many different components of an organelle assemble into a functional structure at an appropriate place and time? Flagellar regeneration by the biflagellate green alga Chlamydomonas is one experimental system in which genetics, biochemistry and ultrastructural analysis are being combined to investigate the assembly of a microtubule-containing organelle. Recent advances in the molecular biology of this 'green yeast' have made possible several new approaches to the problem of flagellar assembly; insights from these new approaches are the focus of this review.
Johnson
K A
KA
Department of Biology, Yale University, New Haven, CT 06511-8112, USA.
Rosenbaum
J L
JL