Dynamics of structural changes in the retina during long-term exposure to bright light.
Exposure to high-intensity light led to pronounced destructive changes in the retina and focal loss of layers formed by neurosensory cells in rats. Photoinjury led to progressive decrease in the numerical density of nuclei in the outer nuclear layer (by 30% after 2 days, by 75% after 1 week, and more than by 90% after 2 weeks of exposure). After 30 days the photosensory layer completely disappeared, while the outer nuclear layer was presented by solitary nuclei of neurosensory cells.
Logvinov
S V
SV
Department of Histology, Cytology, and Embryology, Siberian State Medical University, Tomsk. slogvinov@mail.ru
Potapov
A V
AV
Varakuta
E Yu
EY
Drobatulina
D A
DA
D000818:Animals; D002829:Choroid / Q000098:blood supply / Q000528:radiation effects* / Q000648:ultrastructure; D005260:Female; D008027:Light / Q000009:adverse effects*; D008297:Male; D009474:Neurons / Q000473:pathology / Q000528:radiation effects / Q000648:ultrastructure; D010857:Pigment Epithelium of Eye / Q000473:pathology / Q000528:radiation effects* / Q000648:ultrastructure; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D051381:Rats; D012160:Retina / Q000473:pathology / Q000528:radiation effects* / Q000648:ultrastructure; D012162:Retinal Degeneration / Q000209:etiology / Q000473:pathology*; D013997:Time Factors