Inflammatory arthritis secondary to metastatic gastric cancer.
Metastatic spread of malignancy to the joints is rare and only a few cases of solid tumors have been reported. We describe a patient with inflammatory arthritis of the knee and ankle secondary to metastatic gastric adenocarcinoma to the joints and bone diagnosed by synovianalysis. Arthritis secondary to metastatic cancer is a poor prognostic sign. The diagnosis is based on a strong clinical suspicion, magnetic resonance imaging, and joint fluid cytology or synovial biopsy.
Metyas
Samy K
SK
Division of Rheumatology and Immunology, Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles County/USC Medical Center, 2015 Zonal Avenue, Los Angeles, CA 90033, USA.
Lum
Christopher A
CA
Raza
Anwar S
AS
Vaysburd
Marina
M
Forrester
Deborah M
DM
Quismorio
Francisco P
FP
D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary*; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000473:pathology*; D001859:Bone Neoplasms / Q000556:secondary*; D005122:Exudates and Transudates; D017809:Fatal Outcome; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011859:Radiography; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*; D013582:Synovial Fluid / Q000166:cytology