Simultaneous acquisition of multiple orders of intermolecular multiple-quantum coherence images.
Recent studies have demonstrated the ability to detect images based on intermolecular multiple-quantum coherences (iMQCs) that correspond to flipping of two or more separated spins simultaneously, as opposed to conventional magnetic resonance where only one spin is flipped at a time. Until now, iMQC imaging has only acquired one coherence signal per pulse sequence. Here we report a new sequence that successfully detects five orders of coherence (2, 1, 0, -1, and -2-quantum coherence images) in one pulse sequence, with each signal having its full intensity. The simultaneous acquisition highlights substantial contrast differences between conventional and iMQC images, and between the different types of iMQC images.
Tang
Xiaoping
X
Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Ong
Henry
H
Shannon
Kerry
K
Warren
Warren S
WS
D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D012815:Signal Processing, Computer-Assisted