Vesicle budding: insights from cell-free assays.
Transfer of proteins and lipids between the various membrane-bound subcellular compartments of the eukaryotic cell is mediated by transport vesicles. The development of cell-free assays has allowed rapid progress towards a molecular description of the formation, or budding, of these vesicles. This article reviews and integrates data obtained from various yeast and mammalian systems on molecules involved in the budding reaction.
Melançon
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Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA.
Franzusoff
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A
Howell
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KE