title: [Pulmonary Infiltrate, Pleural Effusion and IgM Macroglobulinaemia].
abstract: We report a 71-year-old mam with known IgM- Macroglobulinemia, who developed infiltrative pulmonary changes and a pleural effusion. Both, the pleural effusion and bronchoalveolar lavage revealed monoclonal IgM positive B-lymphocytoes. Transbronchial biopsies showed tissue infiltrates of lymphoplasmocytic cells, consistent with a pleuropulmonary manifestation of Morbus Waldenstroem. Bone marrow and gastrointestinal involvement could be excluded, and the diagnosis of a primary pulmonary immunocytoma was made. The patient underwent partial lung resection with removal of the affected lung tissue. Pleuropulmonary changes in patients with IgM-Macroglobulinaemia or Morbus Waldenstroem may be due to pulmonary involvement by the hematological disease.
authors.affiliation: Abteilung für Pneumologie, Zentrum für Innere Medizin. reichenf@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Reichenberger
authors.forename: J U
authors.initials: JU
authors.lastname: Heberlein
authors.forename: A
authors.initials: A
authors.lastname: Müller
authors.forename: H
authors.initials: H
authors.lastname: Wirtz
authors.forename: J
authors.initials: J
authors.lastname: Schauer
mesh_terms: D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D008297:Male; D010996:Pleural Effusion / Q000209:etiology* / Q000276:immunology; D016896:Treatment Outcome; D008258:Waldenstrom Macroglobulinemia / Q000209:etiology / Q000276:immunology* / Q000503:physiopathology*
chemical_list: D007075:Immunoglobulin M