title: Angioplasty and stenting for high-grade internal carotid artery stenosis: safety study in 39 selected patients.
abstract: BACKGROUND
  Carotid angioplasty and stenting (CAS) is sometimes used as an alternative to surgery, despite the lack of evidence for its safety and efficacy.
  
  
  METHODS
  Over a 33-month period, 39 consecutive patients with a stenosis >/=70% underwent CAS (4 in a randomized trial and 35 because of contra-indications for surgery).
  
  
  RESULTS
  In 5 patients (13%; 95% CI: 3-23), a major complication occurred (3 disabling ischaemic strokes, 1 myocardial infarction, 1 acute interstitial nephropathy). In 7 patients (18%; 95% CI: 6-30), a minor complication occurred (5 transient ischaemic attacks, 1 transient confusional state, 1 non-disabling ischaemic stroke).
  
  
  CONCLUSIONS
  CAS cannot be considered as a routine procedure and should be restricted to high-risk patients unfit for surgery.
authors.affiliation: Department of Neurology (EA 2691), Lille University Hospital, France.
authors.forename: S
authors.initials: S
authors.lastname: Debette
authors.forename: H
authors.initials: H
authors.lastname: Hénon
authors.forename: J Y
authors.initials: JY
authors.lastname: Gauvrit
authors.forename: S
authors.initials: S
authors.lastname: Haulon
authors.forename: M A
authors.initials: MA
authors.lastname: Mackowiak-Cordoliani
authors.forename: C
authors.initials: C
authors.lastname: Gautier
authors.forename: D
authors.initials: D
authors.lastname: Deplanque
authors.forename: C
authors.initials: C
authors.lastname: Lucas
authors.forename: X
authors.initials: X
authors.lastname: Leclerc
authors.forename: M
authors.initials: M
authors.lastname: Koussa
authors.forename: J P
authors.initials: JP
authors.lastname: Pruvo
authors.forename: D
authors.initials: D
authors.lastname: Leys
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D002343:Carotid Artery, Internal / Q000601:surgery*; D016893:Carotid Stenosis / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D015607:Stents; D020521:Stroke / Q000401:mortality; D016896:Treatment Outcome