title: Oxidative cyclization of beta-hydroxyenones with palladium(II): a novel entry to 2,3-dihydro-4H-pyran-4-ones.
abstract: [reaction: see text] A palladium(II)-mediated oxidative cyclization was found to be effective for the preparation of structurally diverse 2,3-dihydro-4H-pyran-4-ones from the corresponding beta-hydroxyenones. Attractive features of this transformation include the ready availability of the starting enones, the regiocontrol, and the easy access of enantiopure 2,3-dihydro-4H-pyran-4-one from the corresponding enantiopure enone.
authors.affiliation: University of Oxford, The Dyson Perrins Laboratory, South Parks Road, OX1 3QY Oxford, UK.
authors.forename: Maud
authors.initials: M
authors.lastname: Reiter
authors.forename: Sandrine
authors.initials: S
authors.lastname: Ropp
authors.forename: Véronique
authors.initials: V
authors.lastname: Gouverneur