[Antimicrobial activity of saponins from Hedera taurica C a r r].
The antibacterial and antifungal action of saponins Sx1, taurozide H2, taurozide I and their effect on bioluminescent system of photobacteria Photobacterium phosphoreum (Cohn) Ford were investigated. Saponins H2 and I had no antimicrobial effect. Saponin Sx1 possessed antifungal activity in vitro with respect to Candida albicans, C. krusei, C. tropicalis. Saponin Sx1 is less toxic to P. phosphoreum than well-known antiseptics--chlorhexedin and miramistin.
Mel'nichenko
E G
EG
Crimea State Medical University, Simferopol.
Kirsanova
M A
MA
Grishkovets
V I
VI
Tyshkevich
L V
LV
Krivorutchenko
Iu L
IuL
D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D035981:Hedera / Q000737:chemistry*; D008163:Luminescent Measurements; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010776:Photobacterium / Q000187:drug effects / Q000502:physiology; D012503:Saponins / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D012503:Saponins