title: The ethical relevance of the standard of care in the design of clinical trials.
authors.affiliation: Department of Clinical Bioethics, National Institutes of Health, Bethesda, MD 20892-1156, USA. fmiller@nih.gov
authors.forename: Franklin G
authors.initials: FG
authors.lastname: Miller
authors.forename: Henry J
authors.initials: HJ
authors.lastname: Silverman
mesh_terms: D003422:Critical Care / Q000941:ethics* / Q000592:standards; D019317:Evidence-Based Medicine / Q000941:ethics; D006801:Humans; D019359:Knowledge; D010344:Patient Advocacy / Q000941:ethics; D018579:Patient Selection / Q000941:ethics; D010919:Placebos / Q000592:standards; D017410:Practice Guidelines as Topic / Q000592:standards*; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000941:ethics* / Q000592:standards; D012107:Research Design / Q000592:standards*; D012121:Respiration, Artificial / Q000379:methods / Q000592:standards; D012128:Respiratory Distress Syndrome / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D010919:Placebos