Role of thrombomodulin in cancer biology.
Effects of malignancy on haemostasis have long been recognized. The role of coagulation factors, anticoagulants and fibrinolytic agents in cancer biology have emerged more recently. Thrombomodulin is a naturally occurring anticoagulant, expressed by numerous epithelial and lymphovascular tumour cells. It may have a role in tumour metastasis.
Iqbal
S
S
Edinburgh Breast Unit, Western General Hospital, Edinburgh, UK.