title: Characterization of pathogenic Escherichia coli in human immunodeficiency virus-related diarrhea in Senegal.
abstract: Stool samples obtained from 594 Senegalese patients were examined for characterization of pathogenic Escherichia coli in human immunodeficiency virus (HIV)-related diarrhea. Multiple virulence genes were observed in stool samples obtained from HIV-infected patients with diarrhea. Enteroaggregative E. coli and enteroinvasive E. coli were present in stool samples obtained from patients with diarrhea significantly more often than in stool samples obtained from patients without diarrhea (P=.000001). Quinolones may be an effective alternative treatment for E. coli-related diarrhea in HIV-infected adults in Senegal.
authors.affiliation: Laboratoire de Bactériologie Expérimentale, Institut Pasteur, Dakar, Sénégal. gassama@pasteur.sn
authors.forename: Amy
authors.initials: A
authors.lastname: Gassama-Sow
authors.forename: Papa S
authors.initials: PS
authors.lastname: Sow
authors.forename: Madoumbé
authors.initials: M
authors.lastname: Guèye
authors.forename: Aïssatou
authors.initials: A
authors.lastname: Guèye-N'diaye
authors.forename: Jean L
authors.initials: JL
authors.lastname: Perret
authors.forename: Souleymane
authors.initials: S
authors.lastname: M'boup
authors.forename: Awa
authors.initials: A
authors.lastname: Aïdara-Kane
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001422:Bacterial Adhesion / Q000187:drug effects; D016022:Case-Control Studies; D002648:Child; D003967:Diarrhea / Q000150:complications* / Q000453:epidemiology / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000150:complications* / Q000453:epidemiology; D005243:Feces / Q000382:microbiology; D005798:Genes, Bacterial / Q000187:drug effects; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D015363:Quinolones / Q000494:pharmacology; D012307:Risk Factors; D012675:Senegal / Q000453:epidemiology; D014774:Virulence / Q000235:genetics*; D037521:Virulence Factors / Q000032:analysis / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D015363:Quinolones; D037521:Virulence Factors