Social network analysis of gene expression data.
To investigate the structure of genomic interaction network, social affiliation network analysis was performed for the yeast gene expression compendium dataset of hundreds of systematic perturbations. Network density and centrality indices of genes and groups of genes revealed the core-peripheral and the significant intermediary players that may be critical for the control of the biological system.
Ohn
Jung Hun
JH
SNUBI: Seoul National University Biomedical Informatics, SNU School of Medicine, 110-799, Korea.
Kim
Jihoon
J
Kim
Ju Han
JH
D019295:Computational Biology; D015870:Gene Expression; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal; D008957:Models, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics*