title: Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp: report from the SENTRY Antimicrobial Surveillance Program (1997-2001).
abstract: Limited data are available on Chryseobacterium spp. leading to an evaluation of the patient demographics and susceptibility patterns for Chryseobacterium spp. collected in the first 5 years of the SENTRY Antimicrobial Surveillance Program (1997 to 2001). Fifty isolates (24 Chryseobacterium meningosepticum, 20 Chryseobacterium indologenes, two Chryseobacterium gleum, and 4 Chryseobacterium spp. isolates) were collected. The highest Chryseobacterium prevalence was detected among the elderly. The most active antimicrobials were the newer quinolones (garenoxacin, gatifloxacin, and levofloxacin, each with a MIC at which 90 percent of the isolates are inhibited [MIC(90)] of 1 micro g/ml and 98.0% susceptibility) followed by rifampin (MIC(90), 2 microg/ml and 85.7% susceptibility). Trimethoprim-sulfamethoxazole, ciprofloxacin, and piperacillin-tazobactam also showed reasonable activity; vancomycin showed poor potency.
authors.affiliation: The Jones Group/JMI Laboratories, North Liberty, Iowa, USA.
authors.forename: Jeffrey T
authors.initials: JT
authors.lastname: Kirby
authors.forename: Helio S
authors.initials: HS
authors.lastname: Sader
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Walsh
authors.forename: Ronald N
authors.initials: RN
authors.lastname: Jones
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D045247:Chryseobacterium / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D015363:Quinolones / Q000494:pharmacology; D014640:Vancomycin / Q000494:pharmacology; D018440:beta-Lactam Resistance
chemical_list: D000890:Anti-Infective Agents; D015363:Quinolones; D014640:Vancomycin