Facile preparation of beta-fluoro amines by the reaction of aziridines with potassium fluoride dihydrate in the presence of Bu4NHSO4.
Potassium fluoride combined with tetrabutylammonium bisulfate is an efficient reagent to convert a variety of aziridines derived from cyclic and acyclic alkenes to beta-fluoro amine derivatives in high yield.
Fan
Ren-Hua
RH
Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, China.
Zhou
Yong-Gui
YG
Zhang
Wan-Xuan
WX
Hou
Xue-Long
XL
Dai
Li-Xin
LX