title: Portal hypertension: return to fetal life to re-attempt differentiation?
abstract: We speculate on the final meaning of the alterations that characterize portal hypertensive enteropathy. The similarity of these alterations with certain morphofunctional characteristics of prenatal splanchnic development makes it possible to hypothesize that the dedifferentiation with return to early stages of development could constitute a portal hypertension induced pathogenic mechanism.
authors.affiliation: Surgery Department I, School of Medicine, Complutense University of Madrid, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Aller
authors.forename: L
authors.initials: L
authors.lastname: López
authors.forename: M P
authors.initials: MP
authors.lastname: Nava
authors.forename: J L
authors.initials: JL
authors.lastname: Arias
authors.forename: H J
authors.initials: HJ
authors.lastname: Durán
authors.forename: J
authors.initials: J
authors.lastname: Arias
mesh_terms: D002454:Cell Differentiation; D005314:Embryonic and Fetal Development; D006801:Humans; D006975:Hypertension, Portal / Q000196:embryology* / Q000473:pathology / Q000503:physiopathology*; D007422:Intestines / Q000098:blood supply / Q000196:embryology* / Q000473:pathology / Q000503:physiopathology*; D008099:Liver / Q000098:blood supply / Q000196:embryology* / Q000473:pathology / Q000503:physiopathology*; D013152:Splanchnic Circulation