Early pattern formation in the developing Drosophila eye.
The formation of complex cellular arrays from unpatterned epithelia is a widespread developmental phenomenon. Insights into the mechanisms regulating this transformation have come from studying the development of the Drosophila compound eye. Pattern formation in the eye primordium is a highly ordered process in which the onset of differentiation is coordinated with synchronization of cell cycle progression. Recent studies have identified a number of genes that are required for early patterning events, and provide a link between the regulation of proliferation and pattern formation.
Thomas
B J
BJ
Department of Biological Chemistry, University of California, Los Angeles, CA 90024, USA.
Zipursky
S L
SL