title: The coiled body.
abstract: The coiled body is a nuclear organelle that contains snRNPs involved in splicing, the non-snRNP splicing factor U2AF and the nucleolar protein fibrillarin. It is highly conserved in evolution and is present in both animal and plant cells. The coiled body is a dynamic structure that can undergo regulated cycles of assembly and disassembly during interphase and mitosis and it may represent a distinct metabolic compartment within the nucleus.
authors.affiliation: European Molecular Biology Laboratory, Meyerhofstrasse 1, Postfach 102209, D6900 Heidelberg, Germany.
authors.forename: A I
authors.initials: AI
authors.lastname: Lamond
authors.forename: M
authors.initials: M
authors.lastname: Carmo-Fonseca