Guillain-Barré syndrome associated with acute neurobrucellosis.
We report the case of a 14-year-old girl with Guillain-Barré syndrome associated with brucellosis due to Brucella melitensis. The diagnosis was established by the isolation of B. melitensis from her blood and by the determination of high levels of Brucella aglutinins in her sera and cerebrospinal fluid. A combination of rifampin, co-trimoxazole and physical therapy resulted in complete healing within 30 days. Antibrucellar treatment continued for 12 weeks. This case report suggests that brucellosis should be kept in mind in the aetiology of Guillain-Barré syndrome in the endemic areas for brucellosis, and bacteriological and serological tests for brucellosis should be performed.
Namiduru
M
M
Department of Infectious Diseases and Clinical Microbiology, Gaziantep University, School of Medicine, Gaziantep, Turkey.
Karaoglan
I
I
Yilmaz
M
M
D000293:Adolescent; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D017347:Brucella melitensis; D002006:Brucellosis / Q000150:complications* / Q000628:therapy; D004338:Drug Combinations; D005260:Female; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000628:therapy; D006801:Humans; D026741:Physical Therapy Modalities; D012293:Rifampin / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D000904:Antibiotics, Antitubercular; D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D012293:Rifampin