title: [Non-Hodgkin's lymphoma with protein S deficiency].
abstract: Venous thrombosis is rare in children. It can be either acquired or of constitutional origin. Thrombosis during non-Hodgkin lymphoma remains exceptional and is usually locally associated to the tumoral process, raising the issue of its tumoral or cruoric nature. The treatment is based on anticoagulation concomitantly to chemotherapy. We report on a 4-year-old boy admitted for mediastinal non-Hodgkin lymphoma, who developed a thrombosis of the superior vena cava associated to protein S-deficiency. The mechanism of thrombosis may have been multifactorial: associated protein S-deficiency, vascular compression, tumoral process and chemotherapy.
authors.affiliation: Unité d'hémato-oncologie pédiatrique, hôpital d'enfants de Rabat, Maroc. kababri@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: El Kababri
authors.forename: M
authors.initials: M
authors.lastname: El Khorassani
authors.forename: L
authors.initials: L
authors.lastname: Hessissen
authors.forename: A
authors.initials: A
authors.lastname: Kili
authors.forename: M N
authors.initials: MN
authors.lastname: Nachef
authors.forename: M
authors.initials: M
authors.lastname: Khattab
authors.forename: F Msefer
authors.initials: FM
authors.lastname: Alaoui
mesh_terms: D002675:Child, Preschool; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008297:Male; D018455:Protein S Deficiency / Q000150:complications / Q000209:etiology*; D013479:Superior Vena Cava Syndrome / Q000209:etiology*; D020246:Venous Thrombosis / Q000209:etiology*