Gatifloxacin and prolonged QT interval.
We report the case of a 54-year-old woman who, while being treated for acute sinusitis with gatifloxacin, presented with syncope and was found to have a markedly prolonged QT interval. After stopping gatifloxacin, the QT interval normalized. We speculate that her episode of syncope was caused by a ventricular arrhythmia that resulted from an increased QT interval.
Ansari
Shoaib R
SR
Department of Internal Medicine, Morristown Memorial Hospital, NJ, USA. shoaib.r.ansari@uth.tmc.edu
Chopra
Nagesh
N
D000208:Acute Disease; D004562:Electrocardiography; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000627:therapeutic use; D000077734:Gatifloxacin; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced*; D008875:Middle Aged; D012852:Sinusitis / Q000188:drug therapy; D013997:Time Factors
D024841:Fluoroquinolones; D000077734:Gatifloxacin