title: Management of patients with squamous cell carcinoma of the lower lip and N0-neck.
abstract: OBJECTIVE
  For lower lip carcinoma, an incidence of 15% of cervical lymph node metastasis at presentation is generally accepted. This is an argument in favour of an expectant approach. The purpose of this study was to compare the results of the different approaches to the clinically negative neck: prophylactic neck dissection, prophylactic neck irradiation and follow-up.
  
  
  METHODS
  The retrospective study included 200 patients with lower lip carcinoma. The following data were evaluated: (1) the incidence of cervical lymph node metastasis in patients with a clinically negative neck; and (2) pathological confirmation of cervical lymph node metastasis.
  
  
  RESULTS
  In the group undergoing prophylactic neck dissection, lymph node metastasis was found microscopically in 20% of the cases. More than half of the patients receiving prophylactic radiotherapy developed bulky neck lymph node metastases. Out of the patients attending the 2-year follow-up 64% developed a clinically positive neck. Cervical lymph node metastases in these patients was proven microscopically in 88% of cases.
  
  
  CONCLUSIONS
  The high incidence of a clinically positive neck, along with the high incidence of neck node metastasis found in neck dissection specimens suggest that elective neck dissection is the treatment of choice for the neck in patients with lower lip carcinoma.
authors.affiliation: Department of Maxillofacial Surgery, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania. alex_bucur2002@yahoo.com
authors.forename: Alexandru
authors.initials: A
authors.lastname: Bucur
authors.forename: Lidia
authors.initials: L
authors.lastname: Stefanescu
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D009333:Neck / Q000473:pathology / Q000601:surgery; D037981:Neck Dissection; D012189:Retrospective Studies