Emerging genotype (GGIIb) of norovirus in drinking water, Sweden.
From May through June 2001, an outbreak of acute gastroenteritis that affected at least 200 persons occurred in a combined activity camp and conference center in Stockholm County. The source of illness was contaminated drinking water obtained from private wells. The outbreak appears to have started with sewage pipeline problems near the kitchen, which caused overflow of the sewage system and contaminated the environment. While no pathogenic bacteria were found in water or stools specimens, norovirus was detected in 8 of 11 stool specimens and 2 of 3 water samples by polymerase chain reaction. Nucleotide sequencing of amplicons from two patients and two water samples identified an emerging genotype designated GGIIb, which was circulating throughout several European countries during 2000 and 2001. This investigation documents the first waterborne outbreak of viral gastroenteritis in Sweden, where nucleotide sequencing showed a direct link between contaminated water and illness.
Nygård
Karin
K
Swedish Institute for Infectious Disease Control, Solna, Sweden.
Torvén
Maria
M
Ancker
Camilla
C
Knauth
Siv Britt
SB
Hedlund
Kjell-Olof
KO
Giesecke
Johan
J
Andersson
Yvonne
Y
Svensson
Lennart
L
D000293:Adolescent; D000328:Adult; D001483:Base Sequence; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D002648:Child; D004196:Disease Outbreaks; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D029322:Norovirus / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D017422:Sequence Analysis, DNA; D013548:Sweden / Q000453:epidemiology; D014871:Water Microbiology; D014881:Water Supply
D012367:RNA, Viral