title: Closure of bronchopleural fistulas using albumin-glutaraldehyde tissue adhesive.
abstract: Bronchopleural fistulas are a life-threatening complication of pulmonary resection. A 21-year-old woman developed a large bronchopleural fistula after undergoing a pneumonectomy for carcinoid tumor. Despite bronchial stump revision and omental coverage, the fistula recurred. The second patient is a 42-year-old woman with a history of multiple thoracotomies who developed a bronchopleural fistula following aortic root replacement. Using either rigid bronchoscopy or thoracoscopy, these fistulas were evaluated and sealed with an albumin-glutaraldehyde tissue adhesive that may have improved strength and biocompatibility compared with other tissue sealants. This approach may be an effective alternative in the treatment of bronchopleural fistulas.
authors.affiliation: Section of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.
authors.forename: Jules
authors.initials: J
authors.lastname: Lin
authors.forename: Mark D
authors.initials: MD
authors.lastname: Iannettoni
mesh_terms: D000328:Adult; D000418:Albumins; D001983:Bronchial Fistula / Q000628:therapy*; D005260:Female; D005976:Glutaral; D006801:Humans; D010995:Pleural Diseases / Q000628:therapy*; D016156:Respiratory Tract Fistula / Q000628:therapy*; D014014:Tissue Adhesives
chemical_list: D000418:Albumins; D014014:Tissue Adhesives; D005976:Glutaral