Salicylic acid peels for the treatment of acne vulgaris in Asian patients.
BACKGROUND
Salicylic acid peels have been introduced as a useful modality in acne treatment. Few studies have examined its efficacy and safety, especially in darker skin.


OBJECTIVE
To assess the efficacy and safety of salicylic acid peels as a treatment for acne vulgaris in Asian patients.


METHODS
Thirty-five Korean patients with facial acne were treated with 30% salicylic acid peels biweekly for 12 weeks. Lesion counts and Dr. Cunliffe's score were assessed by a blinded evaluator. Safety assessments and patient's evaluations were also recorded.


RESULTS
Both inflammatory and noninflammatory acne lesion counts were decreased in proportion to the duration of treatment. Dr. Cunliffe's acne grade was statistically significantly decreased after treatment. The side effects were tolerable in most cases, and all patients were pleased with their peel results. Stratum corneum hydration, skin surface lipid, skin pH, and transepidermal water loss were unchanged from baseline levels.


CONCLUSIONS
Salicylic acid peels are an effective and safe therapy for acne vulgaris in Asian patients.
Lee
Ho-Sup
HS
Department of Dermatology, Korea University College of Medicine, 126-1, 5-Ka Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea.
Kim
Il-Hwan
IH
D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D002615:Chemexfoliation; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D007723:Korea; D020156:Salicylic Acid / Q000627:therapeutic use*; D013997:Time Factors
D007641:Keratolytic Agents; D020156:Salicylic Acid