title: Losartan induced fetal toxicity.
abstract: Losartan is a specific angiotensin II receptor antagonist. Although the teratogenic effects of angiotensin converting enzyme (ACE) inhibitors are well documented there are limited reports of losartan induced fetal toxicity. The authors report a case of incomplete ossification of skull bones, transient oliguria and feed intolerance in a newborn following in-utero exposure to losartan.
authors.affiliation: Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Bonilla
authors.initials: B
authors.lastname: Nayar
authors.forename: Ashwani
authors.initials: A
authors.lastname: Singhal
authors.forename: Rajiv
authors.initials: R
authors.lastname: Aggarwal
authors.forename: Neena
authors.initials: N
authors.lastname: Malhotra
mesh_terms: D000014:Abnormalities, Drug-Induced; D000959:Antihypertensive Agents / Q000506:poisoning*; D005260:Female; D005313:Fetal Death / Q000139:chemically induced*; D006330:Heart Defects, Congenital / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D019808:Losartan / Q000506:poisoning*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy
chemical_list: D000959:Antihypertensive Agents; D019808:Losartan