title: Multilocular renal cysts with renal cell carcinoma: report of four cases.
abstract: According to Bosniak's classification, renal cysts with moderate calcification, irregular margins, and thickened enhanced septa should raise a suspicion of malignancy. Diagnosis of multilocular renal cysts depends on their histological features. Since 1951, it has generally been considered that a multilocular renal cyst can change from a benign lesion to one which may be combined with malignant change. According to a report from Japan, multilocular renal cysts with renal cell carcinoma are uncommon, and the reported incidence was about 9%. A radical nephrectomy was performed for malignant change. Herein, we present 4 cases of multilocular cyst (Bosniak's class IV) with renal cell carcinoma and review the related literature for their pathogenesis and management.
authors.affiliation: Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Taipei.
authors.forename: Chia-Hsi
authors.initials: CH
authors.lastname: Chen
authors.forename: Cheng-Keng
authors.initials: CK
authors.lastname: Chuang
authors.forename: Chun-Te
authors.initials: CT
authors.lastname: Wu
authors.forename: Kwai-Fong
authors.initials: KF
authors.lastname: Ng
authors.forename: Shuen-Kuei
authors.initials: SK
authors.lastname: Liao
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D007690:Polycystic Kidney Diseases / Q000150:complications* / Q000473:pathology