title: Osteosarcoma of the jaws in children.
abstract: Two cases of osteosarcoma of the jaws in children are reported. One patient was a 13-year-old girl whose first symptoms included nasal and maxillary sinus congestion, followed by epistaxis. She was found to have chondroblastic osteosarcoma extending through the left maxillary alveolar process and sinus. Following surgery and chemotherapy, the patient has been free of disease for 7 years. The second patient, an 8-year-old boy, was diagnosed with juxtacortical (parosteal) osteosarcoma of the mandible, which is a less aggressive variant of the neoplasm. It is believed that this is the youngest patient reported to date with juxtacortical osteosarcoma of the jaws. He was treated by block resection of the right side of the mandible and is free of disease 3(1/2) years later.
authors.affiliation: Department of Pediatric Dentistry, Nova Southeastern University College of Dental Medicine, Fort Lauderdale, Florida, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Donaldson
authors.forename: J R
authors.initials: JR
authors.lastname: Geist
authors.forename: T D
authors.initials: TD
authors.lastname: Daley
mesh_terms: D000293:Adolescent; D002648:Child; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008441:Maxillary Neoplasms / Q000473:pathology*; D008444:Maxillary Sinus Neoplasms / Q000473:pathology; D009361:Neoplasm Invasiveness; D012516:Osteosarcoma / Q000473:pathology*; D018217:Osteosarcoma, Juxtacortical / Q000473:pathology*