title: Expanded chemistry of formamidine ureas.
abstract: [reaction: see text] Formamidine ureas display a rich manifold of reactivity. Thiols induce substitution at the carbonyl carbon to give thiolcarbamates; base-mediated alkylation and acylation occurs at the terminal urea nitrogen, and a new fragmentation/acylation pathway has been uncovered with isocyanates.
authors.affiliation: Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, California 92037, USA.
authors.forename: David D
authors.initials: DD
authors.lastname: Díaz
authors.forename: M G
authors.initials: MG
authors.lastname: Finn