HIV infection presenting as severe autoimmune hemolytic anemia with disseminated intravascular coagulation in an infant.
Autoimmune hemolytic anemia is rare in children. It is generally diagnosed in relation to a viral or bacterial infection but has also been described in association with drugs, autoimmune disease, malignancy, and immunodeficiency. The authors describe a 5-month-old infant who presented with severe autoimmune hemolytic anemia and disseminated intravascular coagulation as his initial manifestation of HIV infection.
Rheingold
Susan R
SR
Divisions of Oncology, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. rheingold@emial.chop.edu
Burnham
Jon M
JM
Rutstein
Richard
R
Manno
Catherine S
CS
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D015658:HIV Infections / Q000175:diagnosis* / Q000628:therapy; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D017701:Reticulocyte Count; D013921:Thrombocytopenia / Q000209:etiology
D006454:Hemoglobins