[Significance of changes in plasma lipid peroxide levels in critically ill patients after liver transplantation].
OBJECTIVE
To investigate the relationship between plasma lipid peroxide (LPO) levels and prognosis in critically ill patients after liver transplantation.


METHODS
Plasma LPO levels were measured in 18 patients within 21 days after liver transplantation, and their relations to the prognosis were analyzed.


RESULTS
Plasma LPO levels were markedly elevated in patients before state of illness got severe, especially in those with fatal outcome. The peak LPO levels were much higher in non-survivors than in survivors, and mortality rate in patients whose plasma LPO exceeding 10 micromol/L (5/6 cases) was significantly higher than those under 10 micromol/L (1/12 cases, P<0.01). The mortality rate in patients with daily fluctuation range of plasma LPO levels over 1.2 micromol.L(-1).d(-1) was higher than those under 1.2 micromol.L(-1).d(-1), and the difference was significant between two groups (P<0.01).


CONCLUSIONS
Measurement of plasma LPO level might be of clinical significance to properly judge the critically ill conditions, and it can be used as routine examination for patients after liver transplantation.
Liu
Chun
C
The Third Hospital of Peking University,Beijing 100083, China.
Zhou
Xiao-si
XS
Geng
Qiu-ming
QM
D000328:Adult; D016638:Critical Illness / Q000628:therapy*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications; D011379:Prognosis
D008054:Lipid Peroxides