title: Adjacent two-level lumbar discectomy: outcome and SF-36 functional assessment.
abstract: METHODS
  A retrospective outcomes study.
  
  
  OBJECTIVE
  To examine the outcome following adjacent two-level lumbar discectomy using both surgeon-based evaluation criteria and validated patient-based quality of life instrument (SF-36).
  
  
  BACKGROUND
  Lumbar discectomies have documented success rates between 49% and 98% for single-level procedures. However, no prior study has specifically examined the outcome following adjacent two-level lumbar discectomy in a large series of patients.
  
  
  METHODS
  This study analyzed 55 patients with a minimum 2-year follow-up. All patients underwent adjacent two-level lumbar discectomy for radicular pain attributable to nerve root impingement at the corresponding levels. The patients were divided into two diagnostic groups based on their preoperative radiographic studies. Patients with two-level adjacent posterolateral lumbar disc herniations without concomitant osseous degenerative changes at the same levels constituted Group 1 (22 patients). Patients with associated osseous degenerative changes at the same levels made up Group 2 (33 patients). The patients' clinical outcome was assessed using the MacNab classification and SF-36 questionnaire.
  
  
  RESULTS
  The average duration of follow-up was 41 months (range 24-96 months). The group consisted of 35 males and 20 females with average age of 49 years (range 19-82 years). Excellent results were observed in 49%, good in 20%, fair in 15%, and poor in 16%. However, patients in Group 1 have 86% excellent/good results, whereas patients in Group 2 have 57% excellent/good results. Overall, 15% of the patients required reoperation and subsequent spinal fusion. Analysis of the SF-36 scores revealed significant differences based on patient's diagnostic grouping as well. Patients in Group 1 have physical and mental summary scores comparable with age- and sex-adjusted population norms and significantly higher than those in Group 2 (P < 0.01).
  
  
  CONCLUSIONS
  Two-level discectomy is an effective treatment with clinical outcome comparable with single-level discectomy. Patients with posterolateral disc herniations and definitive radiculopathy without osseous degenerative changes at the same levels have better clinical outcome and quality of life scores compared with those patients having concomitant degenerative arthritis at the same levels. Patients having two-level discectomy may be at increased risk of requiring subsequent lumbar fusion compared with those with single-level discectomy.
authors.affiliation: Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, USA. Edward.sun@tch.harvard.edu
authors.forename: Edward C
authors.initials: EC
authors.lastname: Sun
authors.forename: Jeffrey C
authors.initials: JC
authors.lastname: Wang
authors.forename: Kevin
authors.initials: K
authors.lastname: Endow
authors.forename: Rick B
authors.initials: RB
authors.lastname: Delamarter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003953:Diagnosis-Related Groups / Q000706:statistics & numerical data; D017586:Diskectomy / Q000379:methods / Q000592:standards*; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000145:classification / Q000601:surgery*; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011788:Quality of Life; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013130:Spinal Stenosis / Q000145:classification / Q000601:surgery*; D011795:Surveys and Questionnaires