A prototype system for retrieval of gene functional information.
Microarrays allow researchers to gather data about the expression patterns of thousands of genes simultaneously. Statistical analysis can reveal which genes show statistically significant results. Making biological sense of those results requires the retrieval of functional information about the genes thus identified, typically a manual gene-by-gene retrieval of information from various on-line databases. For experiments generating thousands of genes of interest, retrieval of functional information can become a significant bottleneck. To address this issue, we are currently developing a prototype system to automate the process of retrieval of functional information from multiple on-line sources.
Folk
Lillian C
LC
Bioinformatics Consortium, School of Medicine, University of Missouri-Columbia, USA.
Patrick
Timothy B
TB
Pattison
Joyce S
JS
Wolfinger
Russell D
RD
Mitchell
Joyce A
JA
D000818:Animals; D019992:Databases as Topic; D001330:Electronic Data Processing; D020869:Gene Expression Profiling; D005796:Genes / Q000502:physiology*; D055614:Genetic Phenomena; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*