title: Summary and recommendations of a National Cancer Institute workshop on issues limiting the clinical use of Monte Carlo dose calculation algorithms for megavoltage external beam radiation therapy.
abstract: Due to the significant interest in Monte Carlo dose calculations for external beam megavoltage radiation therapy from both the research and commercial communities, a workshop was held in October 2001 to assess the status of this computational method with regard to use for clinical treatment planning. The Radiation Research Program of the National Cancer Institute, in conjunction with the Nuclear Data and Analysis Group at the Oak Ridge National Laboratory, gathered a group of experts in clinical radiation therapy treatment planning and Monte Carlo dose calculations, and examined issues involved in clinical implementation of Monte Carlo dose calculation methods in clinical radiotherapy. The workshop examined the current status of Monte Carlo algorithms, the rationale for using Monte Carlo, algorithmic concerns, clinical issues, and verification methodologies. Based on these discussions, the workshop developed recommendations for future NCI-funded research and development efforts. This paper briefly summarizes the issues presented at the workshop and the recommendations developed by the group.
authors.affiliation: Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: Benedick A
authors.initials: BA
authors.lastname: Fraass
authors.forename: James
authors.initials: J
authors.lastname: Smathers
authors.forename: James
authors.initials: J
authors.lastname: Deye
mesh_terms: D000465:Algorithms; D006801:Humans; D009010:Monte Carlo Method; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards; D011874:Radiometry / Q000379:methods* / Q000592:standards*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000592:standards*; D020266:Radiotherapy, Conformal / Q000379:methods / Q000592:standards; D011882:Radiotherapy, High-Energy / Q000379:methods* / Q000592:standards*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014481:United States