[Expression of inducible nitric oxide synthase in allergic fungal rhinosinusitis].
OBJECTIVE
To investigate the expression of inducible nitric oxide synthase(iNOS) in the mucus involved in allergic fungal rhinosinusitis(AFRS) and chronic sinusitis(CRS).


METHODS
The iNOS expression was examined using immunohistochemistry in cases of AFRS as well as CRS.


RESULTS
The expression rate of iNOS in AFRS was significantly higher than in CRS.


CONCLUSIONS
The increased expression of iNOS may involve in AFRS pathogenesis. Statistical difference between AFRS and CRS groups may indicate two groups may be distinct diseases entity.
Hu
Jin
J
Department of Otolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Cui
Yonghua
Y
Wei
Minghui
M
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000201:enzymology*; D009297:Nasal Mucosa / Q000201:enzymology; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D052247:Nitric Oxide Synthase Type II; D012220:Rhinitis / Q000201:enzymology* / Q000382:microbiology; D012221:Rhinitis, Allergic, Perennial / Q000201:enzymology / Q000382:microbiology; D012852:Sinusitis / Q000201:enzymology* / Q000382:microbiology
C496319:NOS2 protein, human; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II