[Ataxic Guillain-Barré syndrome with delayed facial diplegia].
We described a patient with ataxic Guillain-Barré syndrome who subsequently developed facial diplegia. A 38-year-old man developed ataxia, distal limb paresthesias, mild dysphagia, urinary retention and orthostatic hypotension a week after an episode of laryngitis. He had high titers of serum anti-GQ1b, anti-GD1b, anti-GM1b, anti-GT1a, and anti-GD1a IgG antibodies during the acute phase. Although the initial symptoms markedly improved by intravenous immunoglobulin therapy, asymmetric facial diplegia subsequently occurred and remained longer than ataxia. Similar course of facial nerve palsy has been reported in patients with Fisher syndrome. Common pathophysiological mechanism may function in the development of delayed facial diplegia in Fisher syndrome and ataxic Guillain-Barre syndrome.
Atsumi
Masahiko
M
Department of Neurology, Baba Memorial Hospital.
Kitaguchi
Masataka
M
Chimoto
Yuko
Y
Nishikawa
Shogo
S
Mineta
Haruyuki
H
Nakasaka
Yoshikuni
Y
Tanaka
Hisashi
H
Susuki
Keiichiro
K
D000328:Adult; D001259:Ataxia / Q000150:complications*; D005158:Facial Paralysis / Q000209:etiology*; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000628:therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D019846:Miller Fisher Syndrome; D010292:Paresthesia / Q000209:etiology
D016756:Immunoglobulins, Intravenous