Optimal specimen site for diagnosis of nasal T/NK cell lymphoma and treatment including bone marrow transplantation.
Nasal T/NK cell lymphoma is characterized by unrelenting progressive ulceration and necrosis of the nasal cavity and midline facial tissues. Computer tomography scans and biopsy specimens from 4 cases were studied in order to determine the optimal sampling site. Specimens should be from the lateral plate of the nasal cavity and the inferior turbinate. Bone marrow transplantation was performed in 2 cases following chemotherapy and radiotherapy. The combination of chemotherapy, radiotherapy, and bone marrow transplantation has some ability to control the disease.
Sakamoto
Masayuki
M
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. sakamoto@rigid.com
Miyairi
Yasuo
Y
Ishizawa
Mitsugu
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D044963:Biopsy, Fine-Needle; D016026:Bone Marrow Transplantation / Q000379:methods; D017024:Chemotherapy, Adjuvant / Q000379:methods; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D011241:Prednisone / Q000008:administration & dosage; D018714:Radiotherapy, Adjuvant / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone