Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities.
Aristolactams, having a phenanthrene chromophore are a small group of compounds mainly found in the Aristolochiaceae together with the aristolochic acids and 4,5-dioxoaporphines. In this report, these three important classes of natural products are reviewed and classified on the basis of their oxygenation pattern. In addition the biological activities of these compounds and their general chemistry are discussed.
Kumar
Vineet
V
Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110 007, India.
Poonam
Prasad
Ashok K
AK
Parmar
Virinder S
VS
D029065:Aristolochiaceae / Q000737:chemistry*; D034341:Aristolochic Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification / Q000494:pharmacology; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013329:Structure-Activity Relationship
D034341:Aristolochic Acids; D001685:Biological Factors; D007769:Lactams; D010616:Phenanthrenes; D011166:Porphyrins