Role of proton magnetic resonance spectroscopy in the diagnosis of gliomatosis cerebri: a unique pattern of normal choline but elevated Myo-inositol metabolite levels.
A patient with histologically proven gliomatosis cerebri presented with a normal choline level but a markedly abnormal elevated myo-inositol level on magnetic resonance (MR) spectroscopy. We describe the case presentation, imaging findings (in particular, the unique MR spectroscopic pattern), and their significance regarding the diagnosis of this relatively rare neoplasm.
Mohana-Borges
Aurea V R
AV
Department of Radiology, Medical Center, University of California-San Diego, 200 W. Arbor Drive, San Diego, CA 92103, USA.
Imbesi
Steven G
SG
Dietrich
Rosalind
R
Alksne
John
J
Amjadi
Darius K
DK
D000368:Aged; D001932:Brain Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D002794:Choline / Q000032:analysis*; D006801:Humans; D007294:Inositol / Q000032:analysis*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology
D007294:Inositol; D002794:Choline