title: Electrocardiographic J wave as a result of hypercalcemia aggravated by thiazide diuretics in a case of primary hyperparathyroidism.
abstract: Electrocardiographically, the QT interval is shortened, ST segment is depressed, and T wave becomes negative in hypercalcemia. The use of diuretics in cases with hyperparathyroidism decreases the excretion of calcium, causes changes in bone-calcium turnover and parathyroid hormone activity, and forms hypercalcemia. A 67 year-old Turkish female patient in whom we electrocardiographically observed a J wave is presented as a hypercalcemic case with primary, hyperparathyroidism aggravated by the use of a thiazide diuretic.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Topsakal
authors.forename: Hayrettin
authors.initials: H
authors.lastname: Sağlam
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Arinç
authors.forename: Namik Kemal
authors.initials: NK
authors.lastname: Eryol
authors.forename: Servet
authors.initials: S
authors.lastname: Cetin
mesh_terms: D000368:Aged; D001581:Benzothiadiazines; D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D004232:Diuretics; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced / Q000503:physiopathology*; D006961:Hyperparathyroidism / Q000188:drug therapy* / Q000378:metabolism; D010281:Parathyroid Hormone / Q000378:metabolism; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects*
chemical_list: D001581:Benzothiadiazines; D004232:Diuretics; D010281:Parathyroid Hormone; D049993:Sodium Chloride Symporter Inhibitors; D002118:Calcium