title: Arylation of heterocycles via rhodium-catalyzed C-H bond functionalization.
abstract: [reaction: see text] A new method for the rhodium-catalyzed arylation of a variety of heterocycles has been developed. The reaction provided moderate to good yields of the arylated products. A preliminary mechanistic investigation of this reaction revealed the intermediacy of an isolable N-heterocyclic carbene complex.
authors.affiliation: Center for New Directions in Organic Synthesis, Department of Chemistry, Lawrence Berkeley National Laboratory, University of California, Berkeley, California 94720, USA.
authors.forename: Jared C
authors.initials: JC
authors.lastname: Lewis
authors.forename: Sean H
authors.initials: SH
authors.lastname: Wiedemann
authors.forename: Robert G
authors.initials: RG
authors.lastname: Bergman
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Ellman
mesh_terms: D002384:Catalysis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D007093:Imidazoles / Q000138:chemical synthesis*; D008956:Models, Chemical; D012238:Rhodium / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D007093:Imidazoles; D012238:Rhodium