Chemotherapy-related cognitive dysfunction in breast cancer.
OBJECTIVE
To provide an overview of chemotherapy-related cognitive dysfunction in breast cancer survivors, focusing on its pathophysiology, risk factors, assessment, and management.


METHODS
Published biomedical literature.


CONCLUSIONS
Chemotherapy-related cognitive dysfunction in patients with breast cancer is multifactorial and possibly related to anemia or a direct effect of chemotherapy on brain function. Clinical observation and subjective reports are useful assessments. Therapies directed at alleviating or preventing cognitive deficits are being investigated.


CONCLUSIONS
Oncology nurses are important in monitoring cognitive function in patients with breast cancer receiving chemotherapy. Nurses who are aware of the risks, assessment, and management of cognitive impairment are better able to discuss these issues with patients and caregivers.
O'Shaughnessy
Joyce
J
Baylor Sammons Cancer Center, US Oncology, Dallas, TX, USA.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000451:nursing*; D003072:Cognition Disorders / Q000139:chemically induced* / Q000451:nursing*; D005260:Female; D006801:Humans; D024802:Nurse's Role; D009730:Nursing Assessment; D015404:Nursing Methodology Research; D009859:Oncology Nursing / Q000592:standards; D010353:Patient Education as Topic / Q000379:methods; D011788:Quality of Life