[Improvement of methods for indication of the causative agents of natural focal infections under conditions of emergency situations with epidemiologic consequences].
The improvement of the laboratory diagnostics of quarantine infections (QI) is aimed at obtaining the result at a shorter time, the simplification of making serological reactions, enhancing the specificity and sensitivity of the results due to the introduction of new = generation diagnostic preparations into practical use. The wide practical use of erythrocytic and immunofluorescent diagnostic preparations has shown that they cannot completely meet all requirements simultaneously. The optimized scheme of the indication of the causative agents of QI must ensure the combined use, at different stages of the analysis, of magneto-immunosorbents, enzyme immunoassay, as well as immuno-suspension preparations for the simplification and acceleration of obtaining results with sufficient sensitivity and specificity provided.
Efremenko
V I
VI
Research Institute for Plague Control, Stavropol.
Zaĭtsev
A A
AA
Zharnikova
I V
IV
Bogdanov
I K
IK
D001419:Bacteria / Q000276:immunology / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000175:diagnosis* / Q000209:etiology; D003141:Communicable Diseases / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D011790:Quarantine; D012426:Russia / Q000453:epidemiology; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods; D013997:Time Factors