Soy leaf lowers the ratio of non-HDL to HDL cholesterol in hamsters.
The present study was to examine effect of soy leaf powder (SLP) and soy leaf ethanol extract (SLEE) on serum lipoproteins in hamsters. The control group was fed a semisynthetic diet containing 0.1% cholesterol, while the tested groups were maintained on the same diet but supplemented with 3% SLP or the equivalent amount of SLEE derived from 3% SLP for 4 weeks. SLP supplementation led to a trend of lowering serum total cholesterol (TC) and nonhigh density lipoprotein cholesterol (non-HDL-C), with HDL-C being unaffected, whereas incorporation of SLEE into the diet led to an elevated level of HDL-C and a lower level of non-HDL-C with TC being unchanged. Both SLP and SLEE supplementation caused favorably a decrease in the ratio of non-HDL-C to HDL-C. The present results demonstrate that not only soybean seeds but also soy leaves are cardioprotective, by favorably modulating serum lipid profile.
Ho
Hing Man
HM
Food & Nutritional Sciences Programme, Department of Biochemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, The People's Republic of China.
Leung
Lai Kwok
LK
Chan
Franky L
FL
Huang
Yu
Y
Chen
Zhen-Yu
ZY
D000818:Animals; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D006224:Cricetinae; D004032:Diet; D004043:Dietary Fiber / Q000032:analysis; D004435:Eating; D005243:Feces / Q000737:chemistry; D008055:Lipids / Q000032:analysis / Q000097:blood; D008099:Liver / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage*; D018515:Plant Leaves; D013025:Glycine max; D013261:Sterols / Q000032:analysis
D008076:Cholesterol, HDL; D004043:Dietary Fiber; D008055:Lipids; D010936:Plant Extracts; D013261:Sterols; D002784:Cholesterol