title: Soy leaf lowers the ratio of non-HDL to HDL cholesterol in hamsters.
abstract: The present study was to examine effect of soy leaf powder (SLP) and soy leaf ethanol extract (SLEE) on serum lipoproteins in hamsters. The control group was fed a semisynthetic diet containing 0.1% cholesterol, while the tested groups were maintained on the same diet but supplemented with 3% SLP or the equivalent amount of SLEE derived from 3% SLP for 4 weeks. SLP supplementation led to a trend of lowering serum total cholesterol (TC) and nonhigh density lipoprotein cholesterol (non-HDL-C), with HDL-C being unaffected, whereas incorporation of SLEE into the diet led to an elevated level of HDL-C and a lower level of non-HDL-C with TC being unchanged. Both SLP and SLEE supplementation caused favorably a decrease in the ratio of non-HDL-C to HDL-C. The present results demonstrate that not only soybean seeds but also soy leaves are cardioprotective, by favorably modulating serum lipid profile.
authors.affiliation: Food & Nutritional Sciences Programme, Department of Biochemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, The People's Republic of China.
authors.forename: Hing Man
authors.initials: HM
authors.lastname: Ho
authors.forename: Lai Kwok
authors.initials: LK
authors.lastname: Leung
authors.forename: Franky L
authors.initials: FL
authors.lastname: Chan
authors.forename: Yu
authors.initials: Y
authors.lastname: Huang
authors.forename: Zhen-Yu
authors.initials: ZY
authors.lastname: Chen
mesh_terms: D000818:Animals; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D006224:Cricetinae; D004032:Diet; D004043:Dietary Fiber / Q000032:analysis; D004435:Eating; D005243:Feces / Q000737:chemistry; D008055:Lipids / Q000032:analysis / Q000097:blood; D008099:Liver / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage*; D018515:Plant Leaves; D013025:Glycine max; D013261:Sterols / Q000032:analysis
chemical_list: D008076:Cholesterol, HDL; D004043:Dietary Fiber; D008055:Lipids; D010936:Plant Extracts; D013261:Sterols; D002784:Cholesterol