Two cases of orbital lymphangioma associated with vascular abnormalities of the retina and iris.
OBJECTIVE
To report 2 patients with combined intraocular and orbital vascular abnormalities.


METHODS
Two interventional case reports.


METHODS
Clinical and pathologic findings. INTERVENTION/TESTING: Orbitotomy, fluorescein angiography, magnetic resonance imaging, and radiation therapy.


RESULTS
Two patients presented with vision loss, intermittent proptosis, and cosmetic deformity. These patients had orbital lymphangioma, ipsilateral retinal and iris vascular malformations, and smaller corneal diameter on the affected side.


CONCLUSIONS
The coexistence of these diverse vascular anomalies supports the established hypothesis of pluripotential orbital vascular anlagen. Disruptive influences of various types during embryogenesis or development may produce a variety of congenital orbital and intraocular vascular malformations.
Vavvas
Demetrios
D
Ophthalmic Plastic, Orbital, Reconstructive, and Cosmetic Surgery Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA. vavvasd@is.meei.harvard.edu
Fay
Aaron
A
Watkins
Lynnette
L
D000328:Adult; D001165:Arteriovenous Malformations / Q000150:complications*; D003315:Cornea / Q000002:abnormalities; D005260:Female; D006801:Humans; D007498:Iris / Q000098:blood supply*; D008202:Lymphangioma / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy; D012171:Retinal Vessels / Q000002:abnormalities*; D014463:Ultrasonography