title: Co-administration of caspofungin and cyclosporine to a kidney transplant patient with pulmonary Aspergillus infection.
abstract: A kidney transplant patient on cyclosporine treatment developed focal pneumonia due to Aspergillus fumigatus. The patient was not able to tolerate amphotericin B deoxycholate and was switched to caspofungin. The patient responded favourably without any evidence of toxicity from concomitant use of caspofungin and cylosporine.
authors.affiliation: Department of Internal Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland. veli-jukka.anttila@hus.fi
authors.forename: Veli-Jukka
authors.initials: VJ
authors.lastname: Anttila
authors.forename: Anneli
authors.initials: A
authors.lastname: Piilonen
authors.forename: Matti
authors.initials: M
authors.lastname: Valtonen
mesh_terms: D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy; D000077336:Caspofungin; D016572:Cyclosporine / Q000008:administration & dosage*; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000601:surgery; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D054714:Echinocandins; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000379:methods; D055666:Lipopeptides; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000008:administration & dosage*; D010456:Peptides, Cyclic; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D054714:Echinocandins; D055666:Lipopeptides; D010455:Peptides; D010456:Peptides, Cyclic; D016572:Cyclosporine; D000077336:Caspofungin