Fatal leptospirosis presenting as musculoskeletal chest pain.
After holidaying in Vanuatu, a 24-year-old man presented with pleuritic chest pain and chest wall tenderness thought to be musculoskeletal in origin. He developed fatal acute renal failure, jaundice, respiratory failure, myocarditis and rhabdomyolysis. Subsequent serological results showed a rise in serum titre of antibodies to Leptospira grippotyphosa, from 1 : 50 to 1 : 800, consistent with acute infection.
O'Leary
Fenton M
FM
Intensive Care Unit, PO Box 626, Castle Hill, NSW 1765, Australia. fmoleary@bigpond.com
Hunjan
Jaspal S
JS
Bradbury
Ross
R
Thanakrishnan
Govindasamy
G
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007919:Leptospira / Q000276:immunology; D007922:Leptospirosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology; D009140:Musculoskeletal Diseases / Q000150:complications / Q000175:diagnosis*; D010998:Pleurisy / Q000150:complications; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000175:diagnosis
D000907:Antibodies, Bacterial