title: Tumour invasion: effects of cell adhesion and motility.
abstract: Metastasis is the major cause of failure in cancer therapy. Recent studies of the molecular cell biology of the metastatic process have provided new insights into the mechanisms of cell-cell adhesion, cell-substrate adhesion and cell motility that underly invasion by tumour cells. In this review, Van Roy and Mareel discuss the role of proteins with invasion-promoting and invasion-suppressing functions in metastasis.
authors.affiliation: Laboratory of Molecular Biology, University of Ghent, Ledeganckstraat 35, B-9000 Ghent, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Van Roy
authors.forename: M
authors.initials: M
authors.lastname: Mareel