Serologic evidence of dengue infection before onset of epidemic, Bangladesh.
Dengue fever emerged in Bangladesh in 2000. We tested 225 serum samples from febrile patients and 184 blood donors in 1996 and 1997 for dengue antibodies; 55 (24.4% ) febrile patients had dengue antibodies ( 65.5% with secondary infection pattern), compared with one (0.54%) donor (p <0.001), suggesting that dengue transmission was ongoing well before 1996.
Hossain
M Anowar
MA
ICDDR,B: Centre for Health and Population Research, Mohakhali, Dhaka, Bangladesh. anowar@icdrb.org
Khatun
Mahmuda
M
Arjumand
Farzana
F
Nisaluk
Ananda
A
Breiman
Robert F
RF
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000914:Antibodies, Viral / Q000097:blood*; D001459:Bangladesh / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D021821:Communicable Diseases, Emerging / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D003715:Dengue / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D003716:Dengue Virus / Q000276:immunology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D017678:Sex Distribution
D000914:Antibodies, Viral