A patient with LQTS in whom verapamil administration and permanent pacemaker implantation were useful for preventing torsade de pointes.
A 21-year-old woman with long QT syndrome and missense mutation in HERG (T613M), suffered from repeated attacks of pause dependent torsade de pointes, even though she was given beta-blockers and underwent stellate ganglion block twice at the age of eight. After she received permanent pacemaker implantation and administration of verapamil, no premature beats or pause dependent torsade de pointes was observed.
Komiya
Norihiro
N
Third Department of Internal Medicine, Nagasaki University School of Medicine, Sakamoto, Nagasaki, Japan. nkomi@net.nagasaki-u.ac.jp
Tanaka
Kyoei
K
Doi
Yoshiyuki
Y
Fukae
Satoki
S
Nakao
Kojiro
K
Isomoto
Shojiro
S
Seto
Shinji
S
Yano
Katsusuke
K
D000328:Adult; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000628:therapy*; D010138:Pacemaker, Artificial; D019919:Prosthesis Implantation; D016171:Torsades de Pointes / Q000517:prevention & control*; D014700:Verapamil / Q000627:therapeutic use*
D014700:Verapamil