title: Extraesophageal symptoms of GERD.
abstract: Gastroesophageal reflux disease (GERD) can be the primary cause of, or an aggravating contributor to, a wide variety of conditions affecting extraesophageal structures. As a result, GERD can lead to a number of pulmonary symptoms and diseases, otolaryngologic findings and symptoms, and other extraesophageal manifestations, including dental erosions. Clinicians must be aware of the possibility of these extraesophageal reflux-related conditions, even in the absence of classic esophageal symptoms of GERD. While antireflux therapy is often helpful, response to treatment is less predictable than it is for typical GERD.
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: DeVault
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004943:Esophagogastric Junction / Q000473:pathology*; D005260:Female; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D011379:Prognosis; D012140:Respiratory Tract Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution