Distribution of plasma total homocysteine concentrations in the healthy Iranians.
OBJECTIVE
The distribution of plasma total homocysteine concentrations in a population of South West of Iran Shiraz is described to test for differences in homocysteine concentrations among gender and age groups and those levels reported in other populations.


METHODS
Two hundred one healthy males and 201 healthy females aged >15 years from Shiraz, Iran, were randomly selected. Plasma total homocysteine concentrations were measured using high-performance liquid chromatography.


RESULTS
The mean plasma homocysteine level was significantly higher in men (geometric mean, 7.3 micromol/l) than in women (geometric mean, 6.3 micromol/l, P < 0.001). The geometric mean levels for ages 15-25, 26-36, 37-47, and 48-58, 59-69, and 70-80 years, were 5.9, 5.4, 5.2, 6.7, 7.3, and 7.6 micromol/l in women and 7.5, 8.7, 5.9, 5.9,7.2, and 9.1 micromol/l in men, respectively.


CONCLUSIONS
The homocysteine distribution in a representative sample of people of southwest of Iran indicates age and gender differences, as is found in other populations.
Golbahar
Jamal
J
Department of Biochemistry, Shiraz University of Medical Sciences, Shiraz, Iran. golbaharj@sums.ac.ir
Rezaian
Golamreza
G
Bararpour
Hadi
H
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors
D006710:Homocysteine