title: Pulmonary hamartoma: unusual radiologic appearance.
abstract: A pulmonary nodule was incidentally detected in a 50-year-old man during a routine health evaluation. High-resolution computed tomography (HRCT) showed that the lesion had the appearance of a collection of multiple tiny nodules. Histologic examination of the resected specimen revealed a single hamartoma resembling a bunch of grapes. Pulmonary alveoli and bronchioles were entrapped within the hamartoma with tumor buds appearing in a multicentric manner, thereby producing the unusual HRCT findings. Review of chest radiographs taken over the previous 20 years indicated that the tumor doubling time was 4968 days.
authors.affiliation: Third Department of Internal Medicine, National Defense Medical College, Tokorozawa-city, Saitama, Japan.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Shinkai
authors.forename: Hideo
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Soichiro
authors.initials: S
authors.lastname: Kanoh
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ozeki
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Aida
authors.forename: Kazuo
authors.initials: K
authors.lastname: Motoyoshi
mesh_terms: D006222:Hamartoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed