Salmonella entry into mammalian cells: different yet converging signal transduction pathways?
Salmonella bacteria have evolved means to subvert host cell signal transduction pathways to induce their uptake. Recently, progress has been made towards defining those pathways. Although it is clear that Salmonella evoke different signalling pathways in different cell lines, it is possible that these responses may be triggered by a common mechanism and that the diverse pathways may converge downstream in common effector molecules.
Galán
J E
JE
Department of Microbiology and Molecular Genetics, School of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794-5222, USA.