Tobacco use and dependence.
OBJECTIVE
To review tobacco use and dependence including nicotine pharmacology and addiction, and pharmacologic treatment.


METHODS
Professional journals, books, government publications.


CONCLUSIONS
Smoking is addictive and a major health problem. Habitual nicotine use is central to sustaining smoking dependence. This article provides the necessary basis for understanding nicotine addiction and pharmacologic therapies.


CONCLUSIONS
Nurses' knowledge about nicotine addiction is important in helping patients to quit smoking.
Sohn
Min
M
Department of Physiological Nursing, School of Nursing, N631, 2 Koret Way, Box 0610, University of California San Francisco, San Francisco, CA 94143-0610, USA.
Hartley
Christine
C
Froelicher
Erika Sivarajan
ES
Benowitz
Neal L
NL
D006266:Health Education / Q000379:methods; D006801:Humans; D009538:Nicotine / Q000009:adverse effects* / Q000493:pharmacokinetics; D015404:Nursing Methodology Research; D009859:Oncology Nursing / Q000592:standards*; D012307:Risk Factors; D012907:Smoking / Q000503:physiopathology* / Q000523:psychology; D016540:Smoking Cessation / Q000379:methods; D000074606:Smoking Prevention; D014029:Tobacco Use Disorder / Q000451:nursing* / Q000503:physiopathology* / Q000517:prevention & control / Q000523:psychology; D014481:United States
D009538:Nicotine