title: Possible benefits of triamcinolone-assisted pars plana vitrectomy for retinal diseases.
abstract: OBJECTIVE
  To study the advantages and complications of triamcinolone acetonide (TA)-assisted pars plana vitrectomy (PPV) for various retinal diseases.
  
  
  METHODS
  This report is an interventional case series and nonrandomized study. One hundred seventy-seven eyes from 158 patients underwent PPV with or without TA. Group TA(+) consisted of 94 eyes and group TA(-) consisted of 83 eyes. The improvement in vision and postoperative complications were prospectively studied.
  
  
  RESULTS
  Sixty-two percent of the eyes in group TA(+) and 49% of the eyes in group TA(-) had improved vision after surgery (P = 0.34). Twelve eyes in group TA(+) and 12 eyes in group TA(-) had an intraocular pressure higher than 21 mmHg after the operation, with no statistically significant difference (P = 0.63). Four eyes with proliferative diabetic retinopathy in group TA(+) and five eyes with proliferative diabetic retinopathy in group TA(-) needed an additional filtering surgery. Group TA(+) (five eyes) had a lower incidence (P = 0.041) of reoperation caused by preretinal fibrous membrane formation than group TA(-) (13 eyes). No apparent corneal disorder or infectious signs were found in any eyes.
  
  
  CONCLUSIONS
  Triamcinolone acetonide-assisted PPV appears to be potentially useful to reduce the incidence of reoperation owing to preretinal fibrosis with no serious complications.
authors.affiliation: Department of Ophthlamology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Enaida
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Hata
authors.forename: Akifumi
authors.initials: A
authors.lastname: Ueno
authors.forename: Takao
authors.initials: T
authors.lastname: Nakamura
authors.forename: Toshio
authors.initials: T
authors.lastname: Hisatomi
authors.forename: Miho
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Fujisawa
authors.forename: Taiji
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Ishibashi
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D012086:Reoperation; D012164:Retinal Diseases / Q000188:drug therapy* / Q000601:surgery*; D014222:Triamcinolone Acetonide / Q000627:therapeutic use*; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide