Efficacy of galactomannan antigen in the Platelia Aspergillus enzyme immunoassay for diagnosis of invasive aspergillosis in liver transplant recipients.
The utility of galactomannan antigen for diagnosing invasive aspergillosis was evaluated in 154 liver transplant recipients. Sample agreement was 98.5%, and patient specificity was 87%. Galactomannan positivity correlated with mortality, even when controlled for the number of tests performed. Whether galactomannan positivity identifies a subgroup at risk for poor outcome warrants further evaluation.
Kwak
Eun Jeong
EJ
Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15240, USA.
Husain
Shahid
S
Obman
Asia
A
Meinke
Lisa
L
Stout
Janet
J
Kusne
Shimon
S
Wagener
Marilyn M
MM
Singh
Nina
N
D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis*; D005260:Female; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D007124:Immunoenzyme Techniques; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008351:Mannans / Q000032:analysis*; D008875:Middle Aged
D008351:Mannans; C012990:galactomannan; D005690:Galactose