title: Prevalence of HLA-B27 among donors and recipients for renal and bone marrow transplantation in Mauritius.
abstract: In this study, the frequency of the tissue antigen HLA-B27 is studied in 494 donors and recipients for renal and bone marrow transplantation on the multi-ethnic island of Mauritius, the majority of the population of which is of Indian descent. Although results showed a prevalence rate of 4.3%, inter-racial variation was not observed between the major ethnic groups (P>0.05). These findings are comparable with the results of studies on HLA-B27 prevalence rate in India, and lend support to the argument that the HLA-B27 test should not be used on a routine basis to diagnose HLA-B27-related rheumatic disorders in Mauritius.
authors.affiliation: Department of Health and Medical Sciences, Faculty of Science, University of Mauritius, Reduit, Mauritius. lan.sun@uom.ac.mu
authors.forename: M Chan
authors.initials: MC
authors.lastname: Sun
authors.forename: M
authors.initials: M
authors.lastname: Kissoon
authors.forename: J
authors.initials: J
authors.lastname: Sonoo
authors.forename: A H
authors.initials: AH
authors.lastname: Subratty
mesh_terms: D016026:Bone Marrow Transplantation; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D015796:HLA-B27 Antigen / Q000032:analysis*; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008436:Mauritius; D014019:Tissue Donors
chemical_list: D015796:HLA-B27 Antigen