[Investigation of quantitative and species composition and antifungal drug susceptibility of yeasts isolated from patients with generalized periodontitis complicated by candidosis].
Biological properties of 68 Candida strains isolated from parodontal pockets of patients with generalized parodontitis complicated with candidosis have been investigated. It was established that 72.1 +/- 5.43% of strains belong to Candida albicans. The clinical Candida albicans isolates display high resistance to nystatin and levorin, but they are sensitive to synthetic antifungal drugs 5-fluorocytosine, fluconazol, especially to ketoconazol, itraconazole and to antifungal antibiotic amphotericin B as well.
Kutsyk
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RV
Ivano-Frankivsk State Medical Academy, 2 Galytska St., Ivano-Frankivsk, 76000, Ukraine.
Pavliuk
T D
TD
D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D002177:Candidiasis / Q000382:microbiology*; D026141:Drug Resistance, Multiple, Fungal; D015725:Fluconazole / Q000494:pharmacology; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D007654:Ketoconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009761:Nystatin / Q000494:pharmacology; D010518:Periodontitis / Q000382:microbiology*; D013045:Species Specificity
D000935:Antifungal Agents; D009761:Nystatin; D002174:Candicidin; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole; D005437:Flucytosine; D007654:Ketoconazole