title: The antimicrobial activity of extracts of the lichen Cetraria aculeata and its protolichesterinic acid constituent.
abstract: In this study, the antimicrobial activity of the acetone, diethyl ether and ethanol extracts of the lichen Cetraria aculeata has been investigated. The extracts were tested against twelve bacteria and eight fungi and found active against Escherichia coli, Staphylococcus aureus, Aeromonas hydrophila, Proteus vulgaris, Streptococcus faecalis, Bacillus cereus, Bacillus subtilis, Pseudomonas aeruginosa, Listeria monocytogenes. No antimicrobial activity against the fungi was detected. It was determined that only one substance in the extracts has antimicrobial activity and it was characterized as protolichesterinic acid. The MICs of the extracts and protolichesterinic acid were also determined.
authors.affiliation: Department of Biology, University of Anadolu, 26470 Eskişehir, Turkey.
authors.forename: Ayşen Ozdemir
authors.initials: AO
authors.lastname: Türk
authors.forename: Meral
authors.initials: M
authors.lastname: Yilmaz
authors.forename: Merih
authors.initials: M
authors.lastname: Kivanç
authors.forename: Hayrettin
authors.initials: H
authors.lastname: Türk
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001203:Ascomycota / Q000737:chemistry; D008011:Lichens / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts; C095781:protolichesterinic acid; D015107:4-Butyrolactone