title: [Clinical manifestations in acute Lyme diseases].
abstract: Analyzing the clinical observations of 1343 patients, made in the Kama river region in 1991 to 2002, could establish a number of characteristic syndromes of the acute period of Ixodes tick-borne borreliotosis (ITBB). The early period of the diseases manifested itself as two forms: erythematous in 1041 (77.5%) patients and erythema-free in 302 (22.5%). The erythematous form was characterized by the occurrence of the major clinical marker--erythema migrans at the site of tick suction. In Russia, the clinical features of the acute phase of borreliotosis were marked by the early (at weeks 2-3 of the disease) affliction of different organs (the liver) and systems (the nervous, cardiovascular, and locomotor ones). The leading clinical types of the erythema-free ITBB were neurological, arthromyalgic, influenza-like, cardiovascular, hepatitis, regional lymphadenitis, and mixed. The diagnosis of ITBB is established on the basis of a characteristic epidemiological history, clinical manifestations by taking into account the most common types of its early period and the data of a serological survey by the proposed algorithm.
authors.forename: N N
authors.initials: NN
authors.lastname: Vorob'eva
authors.forename: O N
authors.initials: ON
authors.lastname: Sumlivaia
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D018771:Arthralgia / Q000473:pathology; D025065:Borrelia burgdorferi / Q000276:immunology; D002319:Cardiovascular System / Q000473:pathology; D015787:Erythema Chronicum Migrans / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007299:Insect Bites and Stings / Q000175:diagnosis; D018884:Ixodes; D008099:Liver / Q000473:pathology; D008193:Lyme Disease / Q000097:blood / Q000175:diagnosis*; D008199:Lymphadenitis / Q000473:pathology; D018482:Muscle, Skeletal / Q000473:pathology; D009420:Nervous System / Q000473:pathology; D010146:Pain / Q000473:pathology; D012426:Russia; D012698:Serologic Tests; D013577:Syndrome
chemical_list: D000907:Antibodies, Bacterial