Autofluorescence methods in ophthalmology.
An overview of the fluorophores of the eye, the methods used to measure ocular fluorescence, and the existing or ready-to-market instrumentation for the early diagnosis and monitoring of ophthalmic pathologies is presented. Emphasis is given to the impact that a more detailed knowledge of the fluorophores of the eye, their age and pathology relationship, and the considerable technology-driven progress in optical devices and components has had on the development of new compact yet powerful instruments for population screening and for patient follow-ups, using fluorometry alone or in combination with other optical techniques such as light scattering.
Rovati
Luigi
L
University of Modena and Reggio Emilia and INFM, Department of Information Engineering, Laboratory of Optoelectronics, Via Vignolese 905, I-41100 Modena, Italy. rovati.luigi@unimo.it
Docchio
Franco
F
D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D004867:Equipment Design; D005123:Eye / Q000737:chemistry / Q000378:metabolism*; D005128:Eye Diseases / Q000175:diagnosis* / Q000378:metabolism*; D005453:Fluorescence; D005456:Fluorescent Dyes; D005470:Fluorometry / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D018613:Microscopy, Confocal / Q000295:instrumentation / Q000379:methods; D008856:Microscopy, Fluorescence / Q000295:instrumentation* / Q000379:methods*; D055096:Optical Devices
D005456:Fluorescent Dyes