title: Isolated abdominal wound metastasis from a gastrointestinal stromal tumor.
abstract: BACKGROUND
  Gastrointestinal stromal tumors (GIST) frequently recur even after complete resection. The typical pattern of failure from GISTs is both local and distant with hepatic and peritoneal metastases being most common. Isolated abdominal-wall recurrence from GISTs has not been previously described.
  
  
  OBJECTIVE
  To report an isolated abdominal-wound recurrence in the absence of widespread disease in a patient with GIST.
  
  
  METHODS
  Case report of a GIST and isolated abdominal-wound recurrence after laparoscopic-assisted en bloc resection.
  
  
  RESULTS
  Elderly male patient presented with an isolated abdominal wall incisional recurrence 18 mo after gastric resection and adjuvant imatinib mesylate therapy for a high-grade GIST.
  
  
  CONCLUSIONS
  Complete resection of gastrointestinal stromal tumors followed by imatinib therapy may alter the extent of recurrence.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201, USA.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Cunningham
authors.forename: David
authors.initials: D
authors.lastname: Shibata
authors.forename: Carmine
authors.initials: C
authors.lastname: Volpe
mesh_terms: D034861:Abdominal Wall / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006801:Humans; D000068877:Imatinib Mesylate; D010535:Laparoscopy / Q000009:adverse effects*; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010879:Piperazines / Q000627:therapeutic use; D011183:Postoperative Complications; D011743:Pyrimidines / Q000627:therapeutic use; D017154:Stromal Cells; D013529:Surgical Wound Dehiscence
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate