title: Sarcoidal-type allergic contact granuloma: a rare complication of ear piercing.
abstract: As body piercing is increasingly en vogue, complications are on the rise as well. Biopsies of such lesions can impose special problems to the reviewing dermatopathologist. We present two patients who developed papulonodular lesions at the sites of ear piercings. Unexpectedly, the findings included prominent sarcoidal granuloma formation with confluent areas of fibrinoid necrosis. An infectious etiology was excluded. However, patch testing revealed contact allergy to palladium, platinum, and nickel. Interestingly, histopathologic examination of the patch test sites also demonstrated granuloma formation. These findings suggest that the lesions represent allergic contact granulomas. When confronted with this special type of tissue reaction in skin biopsies of piercing sites, the reviewing dermatopathologist should consider the possibility of an allergic reaction. Careful history and thorough diagnostic procedures, including biopsy of the patch test site can establish the diagnosis of contact allergic granuloma.
authors.affiliation: Department of Dermatology, University of Cologne, Germany.
authors.forename: Claus
authors.initials: C
authors.lastname: Casper
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Groth
authors.forename: Nicolas
authors.initials: N
authors.lastname: Hunzelmann
mesh_terms: D000328:Adult; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000473:pathology; D004431:Ear, External / Q000473:pathology / Q000601:surgery; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008670:Metals / Q000276:immunology; D010328:Patch Tests; D011183:Postoperative Complications; D011677:Punctures / Q000009:adverse effects*; D012507:Sarcoidosis / Q000209:etiology* / Q000473:pathology
chemical_list: D008670:Metals