Obesity and hypertension.
This article has discussed some of the mechanisms involved in the causal relation between obesity and hypertension. Obesity causes a constellation of maladaptive disorders that individually and synergistically contribute to hypertension, among other cardiovascular morbidities. Well-designed population-based studies are needed to assess the individual contribution of each of these disorders to the development of hypertension. In addition, because the control of obesity may eliminate 48% of the hypertension in whites and 28% in blacks, this article has offered an up-to-date on the management of this problem. It is hoped that this article will help scientists formulate a thorough understanding of obesity hypertension and form the basis for more research in this field, which has a huge impact on human life.
El-Atat
Fadi
F
Division of Cardiovascular Diseases, Department of Medicine, State University of New York Health Science Center and Veteran Affairs Hospital, 450 Clarkson Avenue, Brooklyn, NY 11201, USA.
Aneja
Ashish
A
Mcfarlane
Samy
S
Sowers
James
J
D000273:Adipose Tissue / Q000503:physiopathology; D000450:Aldosterone / Q000502:physiology; D015992:Body Mass Index; D002319:Cardiovascular System; D020022:Genetic Predisposition to Disease; D006728:Hormones / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D007249:Inflammation; D007668:Kidney / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D020738:Leptin / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology; D009765:Obesity / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D012084:Renin-Angiotensin System / Q000502:physiology; D013564:Sympathetic Nervous System / Q000503:physiopathology; D013927:Thrombosis
D006728:Hormones; D020738:Leptin; D009479:Neuropeptides; D000450:Aldosterone