title: Microscopic polyangiitis associated with primary biliary cirrhosis.
abstract: We describe a patient with microscopic polyangiitis and primary biliary cirrhosis (PBC) who presented with a non-erosive polyarthritis followed by pulmonary and renal involvement and signs of liver disorder. Detection of pANCA and antimitochondrial antibodies with results of renal and liver biopsies allowed a diagnosis of microscopic polyangiitis and PBC. To our knowledge, this is the first report of an association between the 2 diseases.
authors.affiliation: Department of Rheumatology, University of Bari, Piazza Giulio Cesare 11, 70124 Policlinico, Bari, Italy.
authors.forename: Florenzo
authors.initials: F
authors.lastname: Iannone
authors.forename: Paola
authors.initials: P
authors.lastname: Falappone
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pannarale
authors.forename: Antonietta
authors.initials: A
authors.lastname: Gentile
authors.forename: Vito
authors.initials: V
authors.lastname: Grattagliano
authors.forename: Michele
authors.initials: M
authors.lastname: Covelli
authors.forename: Giovanni
authors.initials: G
authors.lastname: Lapadula
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008099:Liver / Q000098:blood supply / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000276:immunology; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome; D014657:Vasculitis / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D003520:Cyclophosphamide; D011241:Prednisone