title: Slow cooling improved blood lipoprotein composition in hypertensive rats.
abstract: Under normal thermal conditions, hypertensive NISAG rats are characterized by lower plasma levels of high-density lipoproteins and increased coefficient of atherogenicity compared to normotensive Wistar rats. Slow cooling significantly modified fractional composition of plasma lipoproteins in hypertensive rats: decreased the content of low-density lipoproteins, markedly increased the content of high-density lipoproteins, and normalized coefficient of atherogenicity. Our results demonstrated the possibility of correcting disturbances in lipoprotein spectrum in essential hypertension by using thermal exposures.
authors.affiliation: Laboratory of Thermophysiology, Institute of Physiology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. kozyreva@iph.ma.nsc.ru
authors.forename: T V
authors.initials: TV
authors.lastname: Kozyreva
authors.forename: S V
authors.initials: SV
authors.lastname: Lomakina
authors.forename: F V
authors.initials: FV
authors.lastname: Tuzikov
authors.forename: N A
authors.initials: NA
authors.lastname: Tuzikova
mesh_terms: D000818:Animals; D006973:Hypertension / Q000097:blood*; D007036:Hypothermia, Induced; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000032:analysis; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar
chemical_list: D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL