title: Mixed cryoglobulinemia due to chronic hepatitis C with severe pulmonary involvement.
abstract: Pulmonary involvement in cryoglobulinemia usually is mild. We present a rare case of severe lung involvement in mixed cryoglobulinemia. A 73-year-old woman with cryoglobulinemic glomerulonephritis was admitted. Dyspnea appeared suddenly two days later. She received the diagnosis of acute lung injury according to the concept proposed by the American-European Consensus Conference. Management required corticosteroid pulse therapy and plasma exchange. This case is the first description of successful early and long-term management of severe lung involvement observed in cryoglobulinemia. Although she has been free of chest symptoms for seven months, further follow-up may be necessary to assess the potential danger of relapse.
authors.affiliation: Division of Nephrology, the Department of Medicine, Showa University Fujigaoka Hospital, Yokohama.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Suzuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morita
authors.forename: Daisuke
authors.initials: D
authors.lastname: Komukai
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Nakao
authors.forename: Terukuni
authors.initials: T
authors.lastname: Ideura
authors.forename: Ashio
authors.initials: A
authors.lastname: Yoshimura
mesh_terms: D000368:Aged; D003449:Cryoglobulinemia / Q000209:etiology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D007668:Kidney / Q000473:pathology; D012128:Respiratory Distress Syndrome / Q000150:complications*