title: [Use of Gated-SPECT with with 99mTC-MIBI in the evaluation of the prognostic significance of ventricular arrhythmias during a stress test].
abstract: The presence of ventricular complex cardiac arrhythmias in coronary patients, both at rest or during physical exercise, is considered a risk factor for future coronary events or sudden death during long time follow up. The meaning of ventricular complex arrhythmias (VCA) in patients with normal ventricular function and without myocardium ischemia has still not been explained. This study aimed to evaluate if patients with normal ventricular function and no evidence of cardiac ischemia (determined by means of Gated SPECT) who developed VCA during stress test show an increase in cardiac events on later monitoring.
  
  
  METHODS
  All patients were studied by means of an ergometric exercise test using a standard Bruce protocol and Gated SPECT with Methoxyisobutyl Isonitrile-99mTechnetium (99mTC-MIBI). Sixty-seven (67) patients with normal ventricular function and no evidence of cardiac ischemia were included.
  
  
  RESULTS
  13 patients had VCA and 54 had no ventricular arrhythmias during stress test. During the follow up of 681.3 +/- 469 days, none of the 13 patients had sudden death, angina pectoris or myocardium infarction.
  
  
  CONCLUSIONS
  In our sample, the appearance of VCA during stress test in patients without myocardium ischemia and normal ventricular function was not associated with an increase of cardiac events during the monitoring which was carried out.
authors.affiliation: Instituto de Cardiología La Plata, La Plata, República Argentina.
authors.forename: J
authors.initials: J
authors.lastname: Camilletti
authors.forename: J
authors.initials: J
authors.lastname: Erriest
authors.forename: R
authors.initials: R
authors.lastname: Campisi
authors.forename: P
authors.initials: P
authors.lastname: Pedroni
authors.forename: F
authors.initials: F
authors.lastname: Giachello
authors.forename: V
authors.initials: V
authors.lastname: Arregui
authors.forename: L
authors.initials: L
authors.lastname: Illanes
authors.forename: A
authors.initials: A
authors.lastname: Mele
mesh_terms: D001145:Arrhythmias, Cardiac / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005080:Exercise Test; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D018754:Ventricular Dysfunction
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi