[Analysis of the association between the quantity of insoluble particles in intravenously administered solution with adverse drug reactions].
OBJECTIVE
To investigate the possible association between adverse drug reactions and the quantity of insoluble particles in the intravenously administered drugs.


METHODS
The solutions were prepared following the procedures in routine clinical practice, and the quantity of insoluble particles in these solutions were measured before and after the solutions went through the transfusion apparatus.


RESULTS
The quantity of insoluble particles measured after the solutions passed through the transfusion apparatus was consistent with the standard documented in Chinese Pharmacopoeia.


CONCLUSIONS
Adverse intravenous reactions occurring in our hospital has no association with excessive quantity of insoluble particles in the administered drugs.
Wang
Yan
Y
Department of Pharmacy, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. yilan999@hotmail.com
Wang
Gui-fang
GF
Ye
Hai-ying
HY
D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects*; D012995:Solubility; D012996:Solutions
D012996:Solutions