title: Persistent subcutaneous Scedosporium apiospermum infection.
abstract: We report the case of a 52-year-old male heart transplant recipient with a persistent localized subcutaneous infection by Scedosporium apiospermum. This form differs from the most common mycetoma by the absence of granules. The patient showed multiple nodules on the right hand that were surgically removed. Concomitantly, he received oral itraconazole, but the infection persisted for two years, and several surgical interventions were necessary to eradicate the infection. Our case demonstrates that a medical approach alone may be not sufficient to cure this fungal infection.
authors.affiliation: Department of Clinical and Molecular Pathology Instituto Dermopatico d'ell'Immacolata, IDI-IRCCS, Via dei Monti di Creta, 104, 00167 Rome, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Posteraro
authors.forename: Camille
authors.initials: C
authors.lastname: Frances
authors.forename: Biagio
authors.initials: B
authors.lastname: Didona
authors.forename: Richard
authors.initials: R
authors.lastname: Dorent
authors.forename: Brunella
authors.initials: B
authors.lastname: Posteraro
authors.forename: Giovanni
authors.initials: G
authors.lastname: Fadda
mesh_terms: D003881:Dermatomycoses / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000628:therapy; D021681:Scedosporium; D018461:Soft Tissue Infections / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy