title: Metformin and serious adverse effects.
abstract: Attention to known contraindications and intercurrent illness can avoid life-threatening acidosis.
authors.forename: Janelle C
authors.initials: JC
authors.lastname: Nisbet
authors.forename: Joanna M
authors.initials: JM
authors.lastname: Sturtevant
authors.forename: Johannes B
authors.initials: JB
authors.lastname: Prins
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D001315:Australia; D003404:Creatinine / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D016903:Drug Monitoring / Q000379:methods; D019983:Guideline Adherence; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000493:pharmacokinetics; D008657:Metabolic Clearance Rate; D008687:Metformin / Q000009:adverse effects* / Q000493:pharmacokinetics; D008875:Middle Aged; D051437:Renal Insufficiency / Q000139:chemically induced
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin; D003404:Creatinine