title: Primary spinal oligoastrocytoma: a case report.
abstract: BACKGROUND
  Primary oligoastrocytomas of the spinal cord are rare, and the treatment options for low-grade intramedullary tumors are controversial.
  
  
  METHODS
  A 10-year-old girl presented with thoracic scoliosis. Magnetic resonance imaging (MRI) revealed an enhancing intramedullary mass lesion extending from C-5 to T-5, associated with whole spine syringomyelia and syringobulbia. (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET) showed high uptake in the lesion. The patient underwent C-5 to T-5 laminoplastic laminotomy and subtotal removal of the tumor. Histologic examination revealed that the tumor was an oligoastrocytoma without anaplastic findings. Genetic analysis revealed loss of heterozygosity of 1p and 19q but not 10q, which is characteristic of oligodendroglial tumors.
  
  
  CONCLUSIONS
  To our knowledge, this is only the second report describing primary oligoastrocytoma of the spinal cord. Genetic analysis may provide a clue in selecting optimal adjuvant therapies.
authors.affiliation: Department of Neurosurgery, Gunma University School of Medicine, Gunma, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Shimizu
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Saito
authors.forename: Masanori
authors.initials: M
authors.lastname: Aihara
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kurihara
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Keisuke
authors.initials: K
authors.lastname: Ueki
authors.forename: Tomio
authors.initials: T
authors.lastname: Sasaki
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D007796:Laminectomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012600:Scoliosis / Q000175:diagnosis; D013120:Spinal Cord Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D013595:Syringomyelia / Q000175:diagnosis; D013904:Thoracic Vertebrae; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18