title: Cutaneous histoplasmosis in patients with acquired immunodeficiency syndrome.
abstract: Since 1987, the US Centers for Disease Control and Prevention has considered disseminated histoplasmosis an acquired immunodeficiency syndrome (AIDS)-defining illness. Cutaneous manifestations of disseminated disease are diverse and often present as a nondescript rash with systemic complaints. Diagnosis is best established by histopathologic examination with appropriate stains for fungal organisms. Skin lesions often resolve within weeks of initiating treatment. We detail a case of cutaneous histoplasmosis and review its epidemiology, common presentations, diagnosis, and treatment options.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: Joshua David
authors.initials: JD
authors.lastname: Rosenberg
authors.forename: Noah S
authors.initials: NS
authors.lastname: Scheinfeld
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D012871:Skin Diseases / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B