title: Low grade gastric mucosa associated lymphoid tissue lymphoma: treatment strategies based on 10 year follow-up.
abstract: OBJECTIVE
  To deduce strategic guidelines of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities.
  
  
  METHODS
  A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed.
  
  
  RESULTS
  Complete remission was obtained in 24 (82.8%) of 29 patients treated with anti Helicobacter pylori (H pylori) regimen only. The duration to reach complete remission was 12 months (85 percentile, 2-33 months). Five patients showed complete remission with radiation therapy (26-86 months). Two of them were H pylori treatment failure cases.
  
  
  CONCLUSIONS
  H pylori eradication is an effective primary treatment option for low grade MALTOMA and radiation therapy could be considered in patients with no evidence of H pylori infection or who do not respond to H pylori eradication therapy 12 months after successful eradication.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Sang Kil
authors.initials: SK
authors.lastname: Lee
authors.forename: Yong Chan
authors.initials: YC
authors.lastname: Lee
authors.forename: Jae Bock
authors.initials: JB
authors.lastname: Chung
authors.forename: Chae Yoon
authors.initials: CY
authors.lastname: Chon
authors.forename: Young Myoung
authors.initials: YM
authors.lastname: Moon
authors.forename: Jin Kyung
authors.initials: JK
authors.lastname: Kang
authors.forename: In-Suh
authors.initials: IS
authors.lastname: Park
authors.forename: Chang Ok
authors.initials: CO
authors.lastname: Suh
authors.forename: Woo Ik
authors.initials: WI
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D016145:Endoscopy, Digestive System; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology*; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology* / Q000532:radiotherapy*; D008875:Middle Aged; D011706:Pyloric Antrum / Q000382:microbiology / Q000473:pathology; D012074:Remission Induction; D012189:Retrospective Studies; D013276:Stomach Ulcer / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology