title: Self-gated cardiac cine MRI.
abstract: The need for ECG gating presents many difficulties in cardiac magnetic resonance imaging (CMRI). Real-time imaging techniques eliminate the need for ECG gating in cine CMRI, but they cannot offer the spatial and temporal resolution provided by segmented acquisition techniques. Previous MR signal-based techniques have demonstrated an ability to provide cardiac gating information; however, these techniques result in decreased imaging efficiency. The purpose of this work was to develop a new "self-gated" (SG) acquisition technique that eliminates these efficiency deficits by extracting the motion synchronization signal directly from the same MR signals used for image reconstruction. Three separate strategies are proposed for deriving the SG signal from data acquired using radial k-space sampling: echo peak magnitude, kymogram, and 2D correlation. The SG techniques were performed on seven normal volunteers. A comparison of the results showed that they provided cine image series with no significant differences in image quality compared to that obtained with conventional ECG gating techniques. SG techniques represent an important practical advance in clinical MRI because they enable the acquisition of high temporal and spatial resolution cardiac cine images without the need for ECG gating and with no loss in imaging efficiency.
authors.affiliation: Laboratory of Cardiac Energetics, NHLBI, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-1061, USA. larsona@nhlbi.nih.gov
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Larson
authors.forename: Richard D
authors.initials: RD
authors.lastname: White
authors.forename: Gerhard
authors.initials: G
authors.lastname: Laub
authors.forename: Elliot R
authors.initials: ER
authors.lastname: McVeigh
authors.forename: Debiao
authors.initials: D
authors.lastname: Li
authors.forename: Orlando P
authors.initials: OP
authors.lastname: Simonetti
mesh_terms: D000465:Algorithms; D004562:Electrocardiography; D006321:Heart / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*