Cytoplasmic dynein: advances in microtubule-based motility.
It is four years since the discovery that a cytoplasmic form of dynein was able to produce force along microtubules in the opposite direction to kinesin. Recent evidence has supported a role for this cytoplasmic dynein in retrograde organelle transport, as well as other forms of intracellular motility.
Vallee
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Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545, USA.