title: Reflectins: the unusual proteins of squid reflective tissues.
abstract: A family of unusual proteins is deposited in flat, structural platelets in reflective tissues of the squid Euprymna scolopes. These proteins, which we have named reflectins, are encoded by at least six genes in three subfamilies and have no reported homologs outside of squids. Reflectins possess five repeating domains, which are highly conserved among members of the family. The proteins have a very unusual composition, with four relatively rare residues (tyrosine, methionine, arginine, and tryptophan) comprising approximately 57% of a reflectin, and several common residues (alanine, isoleucine, leucine, and lysine) occurring in none of the family members. These protein-based reflectors in squids provide a marked example of nanofabrication in animal systems.
authors.affiliation: Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii-Manoa, 41 Ahui Street, Honolulu, HI 96813, USA.
authors.forename: Wendy J
authors.initials: WJ
authors.lastname: Crookes
authors.forename: Lin-Lin
authors.initials: LL
authors.lastname: Ding
authors.forename: Qing Ling
authors.initials: QL
authors.lastname: Huang
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Kimbell
authors.forename: Joseph
authors.initials: J
authors.lastname: Horwitz
authors.forename: Margaret J
authors.initials: MJ
authors.lastname: McFall-Ngai
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D018076:DNA, Complementary; D049832:Decapodiformes / Q000033:anatomy & histology / Q000737:chemistry* / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D015151:Immunoblotting; D007150:Immunohistochemistry; D008027:Light; D016253:Microscopy, Immunoelectron; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000032:analysis* / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D016415:Sequence Alignment; D012995:Solubility
chemical_list: D000596:Amino Acids; D018076:DNA, Complementary; D011506:Proteins