[FACT: French national registry of acute coronary syndromes. Specific study of French general hospital centers].
The FACT registry is currently the French registry including the greatest number of patients with acute coronary syndromes.


OBJECTIVE
The study presents epidemiologic data, modalities and delays for medical admission.


METHODS
Three thousand nine hundred and two patients were included in FACT by 362 French centers of cardiology between 06/01/2003 and 03/02/2003. One thousand eight hundred and ten patients, who had been placed in the cardiology departments of French general hospitals, were isolated from this registry. The French general hospitals represented 50.8% of the 362 centers. In order to clarify the study, these patients were divided into three groups: group A: patients without ST segment elevation but with suggestive ECG modifications; group B: patients with ST segment elevation; group C: all other patients. The results were mainly studied for groups A and B and compared. These results were also compared to those of the FACT registry and of other registries.


RESULTS
The results show that the average delay for admission is 2.9 h after a first delay between the pain and the help of 6.7 h. The first intervening party is a general practitioner (36.4%) then the SAMU (31.6%) and finally the emergency departments (18.7%). 16.6% of the patients from group B undergo pre-hospital thrombolysis. The recommendations of the European Society of Cardiology are widely applied except for the most recent of them since only 27.6% of the patients from group A having a TIMI score > or = 5 receive an anti-GIIB IIIA treatment. The reasons of the non-prescription of the recommended classes are mostly linked to contra-indication and intolerance. The strategy of coronary reopening mainly depends on the presence or the absence in the department of an available medical equipment for angioplasty. If there is one, the percentage of primary angioplasty reaches 54.2% and the percentage of thrombolysis 7.9%. On the opposite, there is 8.3% of angioplasty and 54.2% of thrombolysis for the unequipped centers. The global mortality reaches 5.8% but is inversely proportional to the level of equipment of the departments: 5.9% for the departments with angioplasty, 11% for the departments with coronarography but without angioplasty and 13.8% for the departments without any interventional equipment. Nevertheless, the age of the patients is different and this influences the results: we notice that the less equipped the department is, the older the patients are.


CONCLUSIONS
The FACT registry and the data from the general hospitals give the opportunity to think about the possibilities to improve the delays of call to the first intervening party (more particularly to the SAMU) but it also allows us to think about how to better organize the geographical distribution giving access to a medical equipment for angioplasty. All these information will also help the cardiologists to gather around the recommendations by convincing them that the benefit/risk ratio is positive.
Dujardin
J J
JJ
Service de cardiologie, centre hospitalier de Douai, BP 740, Douai cedex 59507, France. jjacques.dujardin@ch-douai.fr
Steg
P G
PG
Puel
J
J
Montalescot
G
G
Ravaud
P
P
Goldstein
P
P
Jullien
G
G
Chevalier
B
B
Monassier
J P
JP
Huynh-Ba
O
O
Kempf
C
C
D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D002309:Cardiology; D017023:Coronary Angiography; D004562:Electrocardiography; D004630:Emergencies; D004632:Emergency Medical Services; D005194:Family Practice; D005260:Female; D005602:France; D006760:Hospitalization; D006769:Hospitals, General; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000628:therapy; D017410:Practice Guidelines as Topic; D012042:Registries; D012307:Risk Factors; D013577:Syndrome; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome