title: Aza-Michael addition of nosyloxycarbamates to 2-(trifluoromethyl)acrylates.
abstract: [reaction: see text] The amination of 2-(trifluoromethyl)acrylates, performed by nosyloxycarbamates, gives two different aminated products, the derivatives of alpha-trifluoromethyl beta-amino esters or the aziridines, in high yields by changing the reaction conditions. The aza-Michael addition product was isolated for the first time in this kind of reaction. This finding confirms the aza-MIRC mechanism we previously proposed. Asymmetric induction was also pursued.
authors.affiliation: Dipartimento di Chimica dell'Università degli Studi di Roma La Sapienza, Piazzale Aldo Moro 2, I-00185 Roma, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Colantoni
authors.forename: Stefania
authors.initials: S
authors.lastname: Fioravanti
authors.forename: Lucio
authors.initials: L
authors.lastname: Pellacani
authors.forename: Paolo A
authors.initials: PA
authors.lastname: Tardella