[Rosai-Dorfman disease with orbital and rhinopharyngeal localizations. A case report].
OBJECTIVE
We present a case report of Rosai-Dorfman disease with multiple extranodal involvement and favorable outcome after steroid therapy.


METHODS
Rosai-Dorfman disease was diagnosed in a 17-year-old man with orbital, lacrymal, and rhinopharyngeal localizations. Histopathologic examination of lymphadenopathy biopsy revealed the diagnostic of Rosai-Dorfman disease. We present the histological findings leading to diagnosis and radiological data.


RESULTS
Conservative treatment with oral steroids resulted in the resolution of cervical lymphadenopathy and extranodal lesions. The patient was free of problems nine mouths after discontinuation of his treatment, demonstrating its efficacy and safety.


CONCLUSIONS
Rosai-Dorfman disease is a benign disorder and steroid treatment must be initiated in cases with significant cosmetic deformity.
Ben Ghorbel
I
I
Service de Médecine Interne, Hôpital La Rabta, 1007, Tunis, Tunisie. benghorbelimed@yahoo.com
Bouzaidi
K
K
Chelaifa
K
K
Kchir
M N
MN
Khanfir
M
M
Trabelsi
S
S
Lamloum
M
M
Houman
M H
MH
Miled
M
M
D000293:Adolescent; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009302:Nasopharyngeal Diseases / Q000175:diagnosis / Q000209:etiology*; D009916:Orbital Diseases / Q000175:diagnosis / Q000209:etiology*