title: Efficient synthesis of polysubstituted acylguanidines and guanylureas.
abstract: (Benzotriazol-1-yl)carboximidamides were applied for the preparation of polysubstituted acylguanidines and guanylureas. The reaction sequence utilized mild conditions and gave high yields for final compounds and intermediates. The protocol developed allows for variation of the substituents at all positions of the products.
authors.affiliation: Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Boris V
authors.initials: BV
authors.lastname: Rogovoy
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Cai
authors.forename: Nataliya
authors.initials: N
authors.lastname: Kirichenko
authors.forename: Katherine V
authors.initials: KV
authors.lastname: Kovalenko