Demyelination of nerve fibers in the central nervous system caused by chronic exposure to natural hydrogen sulfide-containing gas.
We studied the effect of natural gas from Astrakhan' gas field on rat brain. The study revealed a specific effect of natural H(2)S-containing gas on myelin sheaths in the brain, which determines its neurotoxicity even at low concentrations in the inspired air.
Solnyshkova
T G
TG
Laboratory of Experimental Cell Pathology, State Research Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow.
D000818:Animals; D001921:Brain / Q000166:cytology*; D001931:Brain Mapping; D003337:Corpus Callosum / Q000166:cytology; D005579:Fossil Fuels / Q000633:toxicity; D006862:Hydrogen Sulfide / Q000633:toxicity*; D008297:Male; D009186:Myelin Sheath / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure; D009412:Nerve Fibers / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D036401:Toxicity Tests, Chronic
D005579:Fossil Fuels; D006862:Hydrogen Sulfide