title: The role  of glutathione in intestinal dysfunction.
abstract: Glutathione plays an important cytoprotective role in the gut. Animal studies have demonstrated that the provisions of glutathione precursors are protective for different types of free-radical-mediated cellular injury. There is a need to clarify the potential role of glutathione supplementation in ischemia-reperfusion injury and inflammatory bowel disease. More speculative is whether treatment with glutathione precursors can modify the progress of colorectal cancer.
authors.affiliation: Department of Surgery, University of Western Australia, Perth, Western Australia, Australia.
authors.forename: Heather
authors.initials: H
authors.lastname: Jefferies
authors.forename: Joan
authors.initials: J
authors.lastname: Bot
authors.forename: Jane
authors.initials: J
authors.lastname: Coster
authors.forename: Alizan
authors.initials: A
authors.lastname: Khalil
authors.forename: John C
authors.initials: JC
authors.lastname: Hall
authors.forename: Rosalie D
authors.initials: RD
authors.lastname: McCauley
mesh_terms: D005978:Glutathione / Q000096:biosynthesis / Q000378:metabolism* / Q000627:therapeutic use*; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy* / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism
chemical_list: D005978:Glutathione