TT virus-positive hepatocellular carcinoma arising from non-cirrhotic liver in an elderly man.
A 43-mm hepatic tumor was incidentally detected by computed tomography in a 72-year-old man. Liver function test results were normal. Serum hepatitis B, C and G viruses were negative, while serum TT virus was positive. Autoantibodies were negative. The patient had no history of alcohol consumption. The tumor was found to be a moderately differentiated hepatocellular carcinoma (HCC) from a resected specimen. Neither lobular inflammation nor fibrosis was observed in the surrounding liver. Intrahepatic hepatitis B virus was not detected. This is a case of non-B, non-C HCC positive for only TT virus arising from a non-cirrhotic liver.
Toshikuni
Nobuyuki
N
Department of Internal Medicine, Ako Central Hospital, Ako.
Kayano
Kouichi
K
Nishioka
Satoshi
S
Mitsunaga
Mikio
M
Omoto
Akiyoshi
A
Nagao
Toshihiko
T
Kojo
Motohisa
M
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology*; D004266:DNA Virus Infections / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology*; D008297:Male; D036542:Tomography, Spiral Computed; D022783:Torque teno virus