Application of radionuclide imaging to hepatic impact injury in rabbits.
OBJECTIVE
To investigate the role and clinical value of radionuclide imaging in hepatic impact injuries in rabbits.


METHODS
Rabbits were experimentally impacted on the liver with BIM-IV bio-impact machine. Liver imaging was performed with 99mTc labeled sodium phytate. Liver blood pool imaging was performed with 99mTc-stannous pyrophosphate labeled red blood cells. The results of radionuclide imaging were compared with the anatomic results.


RESULTS
There was significant difference between the images of the injured liver and the control. Radio diminution and defect were shown in the injured liver areas. Various sorts of abnormal radioactivity distribution were observed with hepatic blood pool imaging. The results of the liver imaging and liver blood pool imaging were accorded with the results of the anatomic findings.


CONCLUSIONS
Radionuclide imaging may well display the changes of hepatocellular structures and functions after injury, which is valuable in locating the concrete injured position and differentiating the injured degrees of liver.
Jin
Rong-bing
RB
Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China. jinrbz@cta.cq.cn
Ma
Xiao-lin
XL
Wen
Jian-liang
JL
Tang
Wei-jia
WJ
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D015601:Injury Severity Score; D008099:Liver / Q000000981:diagnostic imaging* / Q000293:injuries*; D008297:Male; D011817:Rabbits; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D016284:Technetium Tc 99m Pentetate; D014947:Wounds and Injuries / Q000000981:diagnostic imaging*
D016284:Technetium Tc 99m Pentetate