title: [Paraneoplastic opsoclonus-myoclonus syndrome associated with small-cell lung cancer].
abstract: Opsoclonus-myoclonus syndrome was observed in a patient treated for small-cell lung cancer. Opsoclonus presented as anarchic involuntary eye movements associated with myoclonies of the limbs and trunk. Opsoclonus-myoclonus is exceptional and a specific expression among several paraneoplastic manifestations described in small-cell lung cancer. These manifestations develop late after diagnosis of cancer. Presence of anti-neuronal antibodies in the serum (inconstant) is a factor of very poor prognosis.
authors.affiliation: Unité Fonctionnelle d'Oncologie Pulmonaire, Service de Pneumologie (Pr C. Mayaud), Hôpital Tenon, 4, rue de la Chine, 75020 Paris. j.margery@wanadoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Margery
authors.forename: J-P
authors.initials: JP
authors.lastname: Ferroir
authors.forename: C
authors.initials: C
authors.lastname: Epaud
authors.forename: C
authors.initials: C
authors.lastname: Martin
authors.forename: B
authors.initials: B
authors.lastname: Milleron
mesh_terms: D000368:Aged; D018288:Carcinoma, Small Cell / Q000150:complications*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D020361:Paraneoplastic Syndromes, Nervous System / Q000209:etiology*