title: [Effects of ozone therapy on the functional activity of the retina in patients with involutional central chorioretinal dystrophy].
abstract: The retinal electrogenesis was studied in central chorioretinal dystrophy (CCRD) of different stages. The general peculiarities of the ozone-therapy influence on the functional retinal activity typical of any CCRD stage were detected; they comprise: an increasing activity of neurons in the muscular region and a specificity related with the dynamic functional activity of the retinal peripheral segments peculiar of each disease stage. A sharp growth of glial index Cg (b/R12) detected in all patients is indicative of an activated metabolism of Mueller glial cells and of impaired glial-neuron relations in the retina as observed in CCRD. A decreasing Cg, observed after ozone-therapy, is an indirect confirmation of anti-hypoxic effect produced by ozone, which can be regarded as a patho-physiological mechanism of its positive influence on the dynamics of the functional retinal activity. Ozone-therapy is recommended to be implemented with the electroretinography monitoring.
authors.forename: V V
authors.initials: VV
authors.lastname: Neroev
authors.forename: M V
authors.initials: MV
authors.lastname: Zueva
authors.forename: I V
authors.initials: IV
authors.lastname: Tsapenko
authors.forename: A T
authors.initials: AT
authors.lastname: Khandzhian
mesh_terms: D015862:Choroid Diseases / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy*; D004596:Electroretinography; D006801:Humans; D010083:Oxidants, Photochemical / Q000627:therapeutic use*; D010126:Ozone / Q000627:therapeutic use*; D012160:Retina / Q000502:physiology*; D012162:Retinal Degeneration / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy*; D012165:Retinal Ganglion Cells
chemical_list: D010083:Oxidants, Photochemical; D010126:Ozone