Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Saphire
Erica Ollmann
EO
Dept. of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines, La Jolla, California 92037 USA.
Stanfield
Robyn L
RL
Crispin
M D Max
MD
Morris
Garrett
G
Zwick
Michael B
MB
Pantophlet
Ralph A
RA
Parren
Paul W H I
PW
Rudd
Pauline M
PM
Dwek
Raymond A
RA
Burton
Dennis R
DR
Wilson
Ian A
IA
D016915:AIDS Vaccines / Q000276:immunology*; D001665:Binding Sites; D018360:Crystallography, X-Ray; D015195:Drug Design; D006031:Glycosylation; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control*; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000737:chemistry* / Q000276:immunology; D017434:Protein Structure, Tertiary
D016915:AIDS Vaccines; D007074:Immunoglobulin G