Cerebrosides and a monoacylmonogalactosylglycerol from Clinacanthus nutans.
A mixture of nine cerebrosides and a monoacylmonogalactosylglycerol were separated from the leaves of Clinacanthus nutans. The structures of the cerebrosides were characterized as 1-O-beta-D-glucosides of phytosphingosines, which comprised a common long-chain base, (2S,3S,4R,8Z)-2-amino-8(Z)-octadecene-1,3,4-triol with nine 2-hydroxy fatty acids of varying chain lengths (C(16), C(18), C(20-26)) linked to the amino group. The glycosylglyceride was characterized as (2S)-1-O-linolenoyl-3-O-beta-D-galactopyranosylglycerol. The structures were established on the basis of the spectroscopic data and chemical reactions.
Tuntiwachwuttikul
Pittaya
P
Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom 73000, Thailand. pittayat@su.ac.th
Pootaeng-On
Yupa
Y
Phansa
Photchana
P
Taylor
Walter Charles
WC
D027901:Acanthaceae / Q000737:chemistry*; D000107:Acetylation; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D002554:Cerebrosides / Q000737:chemistry*; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D004220:Disulfides; D005347:Fibroblasts / Q000187:drug effects; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
D000893:Anti-Inflammatory Agents; D002554:Cerebrosides; D016861:Cyclooxygenase Inhibitors; D004220:Disulfides; D010936:Plant Extracts; C021181:dimethyl disulfide