title: Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis.
abstract: We report three cases of callosal dysgenesis that were evaluated by diffusion tensor imaging and fiber tractography. In partial agenesis of corpus callosum, fiber tracts from all regions of brain converged to a partially developed small genu portion and connected to the contralateral side. In complete callosal agenesis, fibers from the hemispheres failed to cross the midline and formed thick bundles running anteroposteriorly (eg, Probst bundle). The thickness of the anterior commissure was enlarged or smaller than normal brain, and other white matter tracts were not markedly different from normal brain tissue.
authors.affiliation: Department of Diagnostic Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Seung-Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Susumu
authors.initials: S
authors.lastname: Mori
authors.forename: Dong Joon
authors.initials: DJ
authors.lastname: Kim
authors.forename: Sei Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Si Yeon
authors.initials: SY
authors.lastname: Kim
authors.forename: Dong Ik
authors.initials: DI
authors.lastname: Kim
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000473:pathology; D061085:Agenesis of Corpus Callosum; D016880:Anisotropy; D002552:Cerebral Ventricles / Q000473:pathology; D003337:Corpus Callosum / Q000000981:diagnostic imaging*; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D007231:Infant, Newborn; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000000981:diagnostic imaging* / Q000473:pathology*; D011856:Radiographic Image Enhancement