title: Full-face carbon dioxide laser resurfacing in the management of a patient with the nevoid basal cell carcinoma syndrome.
abstract: BACKGROUND
  Multiple surgical procedures are often a source of discomfort, pain, and disfigurement for patients with the nevoid basal cell carcinoma syndrome (NBCCS).
  
  
  OBJECTIVE
  The patient with NBCCS had approximately 45 identifiable basal cell carcinomas on her face. Multiple Mohs surgeries were performed to remove the largest tumors. A tumor-free plane was not achieved in several lesions despite removal of multiple tissue layers. The treatment of the remaining tumors presented a significant challenge.
  
  
  METHODS
  Full-face CO2 laser resurfacing was performed after curettage and local laser ablation of all visible tumors.
  
  
  RESULTS
  The patient healed well postoperatively. She developed six basal cell carcinomas on her face during the 10-month follow-up period. These were easily treated with Mohs surgery and imiquimod cream.
  
  
  CONCLUSIONS
  CO2 laser resurfacing is a useful surgical modality for treatment of multiple facial basal cell carcinomas in the patients with NBCCS. It allows treatment of all the facial lesions in a single session and minimizes suffering resulting from repeated surgical procedures. Additionally, the layer of skin damaged by ultraviolet radiation is removed, allowing for easier management after resurfacing.
authors.affiliation: Department of Dermatology, Philadelphia College of Osteopathic Medicine, 1259 South Cedar Crest Boulevard, Suite 100, Allentown, PA 18103-6206, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Doctoroff
authors.forename: Steven A
authors.initials: SA
authors.lastname: Oberlender
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Purcell
mesh_terms: D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000601:surgery*; D002245:Carbon Dioxide; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D012878:Skin Neoplasms / Q000601:surgery*
chemical_list: D002245:Carbon Dioxide