title: Clostridium perfringens pleuropulmonary infection and septic shock: case report and population-based laboratory surveillance study.
abstract: We report a rare case of necrotizing pneumonia, empyema, and septic shock caused by Clostridium perfringens. Population-based laboratory surveillance was subsequently conducted that identified an annual incidence of invasive C. perfringens disease of 0.83 per 100,000 population with a striking age-related increased risk for acquisition.
authors.affiliation: Department of Medicine, Calgary Laboratory Services, University of Calgary, and the Calgary Health Region, Calgary, Alberta, Canada.
authors.forename: Shannon
authors.initials: S
authors.lastname: Jackson
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Gregson
authors.forename: Sean
authors.initials: S
authors.lastname: McFadden
authors.forename: Kevin B
authors.initials: KB
authors.lastname: Laupland
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D003015:Clostridium Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003131:Combined Modality Therapy; D018450:Disease Progression; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D004653:Empyema / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013906:Thoracoscopy / Q000379:methods; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents