title: Emerging genotype (GGIIb) of norovirus in drinking water, Sweden.
abstract: From May through June 2001, an outbreak of acute gastroenteritis that affected at least 200 persons occurred in a combined activity camp and conference center in Stockholm County. The source of illness was contaminated drinking water obtained from private wells. The outbreak appears to have started with sewage pipeline problems near the kitchen, which caused overflow of the sewage system and contaminated the environment. While no pathogenic bacteria were found in water or stools specimens, norovirus was detected in 8 of 11 stool specimens and 2 of 3 water samples by polymerase chain reaction. Nucleotide sequencing of amplicons from two patients and two water samples identified an emerging genotype designated GGIIb, which was circulating throughout several European countries during 2000 and 2001. This investigation documents the first waterborne outbreak of viral gastroenteritis in Sweden, where nucleotide sequencing showed a direct link between contaminated water and illness.
authors.affiliation: Swedish Institute for Infectious Disease Control, Solna, Sweden.
authors.forename: Karin
authors.initials: K
authors.lastname: Nygård
authors.forename: Maria
authors.initials: M
authors.lastname: Torvén
authors.forename: Camilla
authors.initials: C
authors.lastname: Ancker
authors.forename: Siv Britt
authors.initials: SB
authors.lastname: Knauth
authors.forename: Kjell-Olof
authors.initials: KO
authors.lastname: Hedlund
authors.forename: Johan
authors.initials: J
authors.lastname: Giesecke
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Andersson
authors.forename: Lennart
authors.initials: L
authors.lastname: Svensson
mesh_terms: D000293:Adolescent; D000328:Adult; D001483:Base Sequence; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D002648:Child; D004196:Disease Outbreaks; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D029322:Norovirus / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D017422:Sequence Analysis, DNA; D013548:Sweden / Q000453:epidemiology; D014871:Water Microbiology; D014881:Water Supply
chemical_list: D012367:RNA, Viral