title: Intrathecal fluorescein to localize cerebrospinal fluid leakage in bilateral mondini dysplasia.
abstract: Recurrent meningitis caused by bilateral Mondini dysplasia presents a difficult diagnostic and therapeutic dilemma. A high-resolution computed tomographic scan with intrathecal contrast provided a false-positive identification for the side of cerebrospinal fluid leak in this patient. We report the intraoperative use of intrathecal fluorescein with mastoid tap to identify the side of cerebrospinal fluid leak in a 16-month-old boy with bilateral Mondini malformations. Both ears had been obliterated for recurrent cerebrospinal fluid leaks, while meningitis occurred after unilateral cochlear implantation.
authors.affiliation: Bobby R. Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: Allen Jung Chen
authors.initials: AJ
authors.lastname: Lue
authors.forename: Spiros
authors.initials: S
authors.lastname: Manolidis
mesh_terms: D002559:Cerebrospinal Fluid Rhinorrhea / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D003051:Cochlea / Q000002:abnormalities* / Q000000981:diagnostic imaging; D019929:Cochlear Implantation / Q000009:adverse effects; D003287:Contrast Media / Q000008:administration & dosage*; D003937:Diagnosis, Differential; D004322:Drainage; D019793:Fluorescein / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007278:Injections, Spinal; D008297:Male; D008581:Meningitis / Q000209:etiology*; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media; D019793:Fluorescein