title: Evidence-based consumer choice: a case study in colorectal cancer screening.
abstract: OBJECTIVE
  To elicit community preferences for colorectal cancer (CRC) screening by faecal occult blood test (FOBT) using discrete choice modeling (DCM). To provide policymakers with information that would assist them in designing the future national screening program.
  
  
  METHODS
  301 participants in central Sydney, aged 50 to 70 years, at 'average' risk of CRC, participated in a face-to-face discrete choice study interview in which screening profiles were posed to derive estimates for preferences for CRC FOBT screening.
  
  
  RESULTS
  Three characteristics were varied in our screening profiles, namely: benefit (CRC deaths prevented); potential harm (false positive induced colonoscopy); and notification policy (of test result). Ninety-four respondents (32%) did not trade off CRC deaths prevented for any reduction in harms. Twelve per cent always chose no screening. The remaining 56% traded benefits and harms. These latter respondents (n = 164) were willing to accept 853 (false positive induced) colonoscopies for one CRC death prevented.
  
  
  CONCLUSIONS
  While survival was all that mattered for just over one-third of the sample and 12% would choose no screening, the remaining individuals were prepared to trade CRC deaths prevented against other characteristics. CRC screening will not receive unqualified community support, irrespective of harms.
  
  
  CONCLUSIONS
  In any future national CRC screening program, consideration of these insights about community assessment of benefits, harms, costs and other characteristics of CRC screening is warranted.
authors.affiliation: Screening Test Evaluation Program, School of Public Health, Surgical Outcomes Research Centre, University of Sydney, A27, NSW 2006. glenns@health.usyd.edu.au
authors.forename: Glenn
authors.initials: G
authors.lastname: Salkeld
authors.forename: Michael
authors.initials: M
authors.lastname: Solomon
authors.forename: Leonie
authors.initials: L
authors.lastname: Short
authors.forename: Mandy
authors.initials: M
authors.lastname: Ryan
authors.forename: Jeanette E
authors.initials: JE
authors.lastname: Ward
mesh_terms: D000368:Aged; D002755:Choice Behavior; D003113:Colonoscopy / Q000706:statistics & numerical data; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000401:mortality; D003955:Diagnostic Tests, Routine / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine; D005260:Female; D017144:Focus Groups; D006801:Humans; D008297:Male; D008875:Middle Aged; D009517:New South Wales; D009780:Occult Blood; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D012044:Regression Analysis; D012959:Socioeconomic Factors