Activity of cell immune response and open field behavior in Wistar and OXYS rats.
The state of the thymus, activity of cell-mediated immunity, and open field behavior were compared in Wistar and OXYS rats (premature aging). Early involution of the thymus was revealed in OXYS rats, which by the type of morphological changes corresponded to accidental involution and was associated with low level of delayed hypersensitivity reaction and decreased motor and exploratory behavior.
Markova
E V
EV
Institute of Clinical Immunology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. evgeniya_markova@mail.ru
Obukhova
L A
LA
Kolosova
N G
NG
D019588:Aging, Premature / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D000818:Animals; D005106:Exploratory Behavior / Q000502:physiology*; D006968:Hypersensitivity, Delayed; D007107:Immune System / Q000166:cytology / Q000502:physiology*; D007111:Immunity, Cellular; D008297:Male; D009043:Motor Activity / Q000235:genetics / Q000502:physiology; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D013950:Thymus Gland / Q000276:immunology / Q000503:physiopathology