Efficient synthesis of chiral alpha- and beta-hydroxy amides: application to the synthesis of (R)-fluoxetine.
Kakei
Hiroyuki
H
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Nemoto
Tetsuhiro
T
Ohshima
Takashi
T
Shibasaki
Masakatsu
M
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry; D005473:Fluoxetine / Q000138:chemical synthesis*; D006865:Hydrogenation; D006900:Hydroxylation; D013237:Stereoisomerism
D000577:Amides; D004852:Epoxy Compounds; D005473:Fluoxetine