title: Functions of pRb and p53: what's the connection?
abstract: The pRb and p53 proteins have tumour suppressor functions and both are regulators of transcription. Their mechanisms of transcriptional regulation are unrelated in many ways--in contrast, it would appear, to their biological functions. This review highlights their biological connections in the light of recent advances in understanding the mechanisms of pRb and p53 function.
authors.affiliation: Wellcome/CRC Institute and the Dept of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK.
authors.forename: T
authors.initials: T
authors.lastname: Kouzarides