Darier's disease restricted to sun-exposed areas.
We report a sporadic case of Darier's disease restricted to sun-exposed areas in a 17-year-old Japanese girl. There are several clinical variants of Darier's disease including unilateral Darier's disease, localized Darier's disease, segmental Darier's disease, and acral Darier's disease, but few cases of Darier's disease restricted to sun-exposed areas have been described in the literature. Although it remains controversial whether UV irradiation can evoke the eruption of Darier's disease or not, cases of Darier's disease restricted to sun-exposed areas like our case may help to further clarify the relationship between Darier's disease, UV irradiation and photo-exacerbation of this autosomal dominant genodermatosis.
Kimoto
M
M
Department of Dermatology, Teikyo University School of Medicine, Ichihara Hospital, 3426-3 Anesaki, Ichihara, Chiba 299-0111, Japan. kimoty@io.ocn.ne.jp
Akiyama
M
M
Matsuo
I
I
D000293:Adolescent; D007644:Darier Disease / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D013472:Sunlight / Q000009:adverse effects*