title: Modification of delayed radiation-induced reactions of duodenal vessels and mast cells in old rats.
abstract: Pronounced ultrastructural changes in vessels and mast cells were observed in duodenal lamina propria of Wistar rats 1 year after single whole-body gamma-irradiation in a dose of 7.5 Gy. Inhibition of adrenocortical function with methopyrone reduced structural damage and improved animal survival.
authors.affiliation: Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk; Institute of Industrial Organic Chemistry, Pschina, Poland. popoutch@mrrc.obninsk.ru
authors.forename: V V
authors.initials: VV
authors.lastname: Popuchiev
authors.forename: L N
authors.initials: LN
authors.lastname: Mikhina
authors.forename: N D
authors.initials: ND
authors.lastname: Yakovleva
authors.forename: A G
authors.initials: AG
authors.lastname: Konoplyannikov
authors.forename: V V
authors.initials: VV
authors.lastname: Yuzhakov
authors.forename: E A
authors.initials: EA
authors.lastname: Odintsova
authors.forename: R A
authors.initials: RA
authors.lastname: Brodskii
authors.forename: L E
authors.initials: LE
authors.lastname: Sevan'kaeva
authors.forename: K
authors.initials: K
authors.lastname: Kita
authors.forename: I
authors.initials: I
authors.lastname: Kita
mesh_terms: D000367:Age Factors; D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D004386:Duodenum / Q000098:blood supply* / Q000187:drug effects / Q000528:radiation effects* / Q000648:ultrastructure; D005500:Follow-Up Studies; D005720:Gamma Rays; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000528:radiation effects* / Q000648:ultrastructure; D008797:Metyrapone / Q000494:pharmacology; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014916:Whole-Body Irradiation
chemical_list: D002395:Catecholamines; D011837:Radiation-Protective Agents; D008797:Metyrapone