Method for testing for human papillomavirus infection in patients with cervical intraepithelial disease.
To determine whether DNA detection of high-risk human papillomavirus could represent a reliable screening technique and a useful follow-up method, we investigated the performance of the Hybrid Capture II assay in detecting high-grade cervical lesions. The test positivity at 1.86 pg/ml had a high sensitivity (94.7%) and improved specificity. It was also a suitable follow-up method for detecting the recurrence of cervical intraepithelial disease in patients.
Lin
Hsing-Pei
HP
Department of Laboratory Medicine, Cathay General Hospital, Taipei, Taiwan, Republic of China.
Huang
Yang-Yang
YY
Wu
Hsueh-Yin
HY
Kao
Jau-Tsuen
JT
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000175:diagnosis*; D002577:Uterine Cervical Diseases / Q000821:virology*
D004279:DNA, Viral