title: Inflammation: a unifying theory for the origin of dry eye syndrome.
abstract: Dry eye syndrome has been difficult to diagnose and treat, due to its heterogeneity. These difficulties are being overcome, however, as evidence becomes available about a common etiology. An inflammatory mechanism apparently underlies the condition. This theory has been proven by use of immunomodulators that show efficacy in treating patients with dry eye syndrome.
authors.affiliation: Cole Eye Institute, Cleveland Clinic Foundation, USA.
authors.forename: Steven E
authors.initials: SE
authors.lastname: Wilson
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D017322:Clinical Trials, Phase II as Topic; D017326:Clinical Trials, Phase III as Topic; D016572:Cyclosporine / Q000008:administration & dosage; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007638:Keratoconjunctivitis Sicca / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D007765:Lacrimal Apparatus / Q000503:physiopathology; D008875:Middle Aged; D013666:Tears / Q000378:metabolism; D014481:United States
chemical_list: D000893:Anti-Inflammatory Agents; D016572:Cyclosporine