Hairy cell leukemia in father and son.
Hairy cell leukemia (HCL) is an uncommon B cell disorder, and familial HCL is rarely encountered among the first degree relatives of HCL patients. A father and son, both of whom developed hairy cell leukemia, is presented in this report. The HLA haplotype shared by the father and son was A2, B18, BW6, CW7, DR3, DR10, and DQ8. Among these haplotypes, HLA A2 and Bw6 have previously been reported.
Cetiner
Mustafa
M
School of Medicine, Department of Hematology, Marmara University, Istanbul, Turkey. mcetiner@ixir.com
Adigüzel
Cafer
C
Argon
Dilek
D
Ratip
Siret
S
Eksioglu-Demiralp
Emel
E
Tecimer
Tulay
T
Bayik
Mahmut
M
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017338:Cladribine / Q000627:therapeutic use; D006239:Haplotypes; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents; D016898:Interferon-alpha; D017338:Cladribine