title: Lack of plasma leptin response to feeding in newborn infants.
abstract: OBJECTIVE
  Previous reports of the postprandial regulation of leptin are controversial, and there have been few studies on the effects of breast-feeding on postprandial regulation in newborn infants. We examined the response of plasma leptin to breast- and formula-feeding in newborn infants.
  
  
  METHODS
  We measured the plasma leptin levels using an enzyme-linked immunosorbent assay kit before and after feeding in 12 breast-fed and 11 formula-fed mature infants.
  
  
  RESULTS
  There was no significant difference in plasma leptin levels in breast-fed infants before and after feeding or in artificially fed infants before and after feeding.
  
  
  CONCLUSIONS
  Our results suggest that feeding does not play a role in the acute response of circulating leptin levels in either breast- or formula-fed infants.
authors.affiliation: Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan. tsimizut@aol.com
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
authors.forename: H
authors.initials: H
authors.lastname: Shoji
authors.forename: K
authors.initials: K
authors.lastname: Hisata
authors.forename: R
authors.initials: R
authors.lastname: Tadokoro
authors.forename: K
authors.initials: K
authors.lastname: Shinohara
authors.forename: S
authors.initials: S
authors.lastname: Shiga
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashiro
mesh_terms: D001942:Breast Feeding; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005526:Food, Formulated; D006801:Humans; D007231:Infant, Newborn; D020738:Leptin / Q000097:blood*; D008297:Male; D013997:Time Factors
chemical_list: D020738:Leptin