Isolated abdominal wound metastasis from a gastrointestinal stromal tumor.
BACKGROUND
Gastrointestinal stromal tumors (GIST) frequently recur even after complete resection. The typical pattern of failure from GISTs is both local and distant with hepatic and peritoneal metastases being most common. Isolated abdominal-wall recurrence from GISTs has not been previously described.


OBJECTIVE
To report an isolated abdominal-wound recurrence in the absence of widespread disease in a patient with GIST.


METHODS
Case report of a GIST and isolated abdominal-wound recurrence after laparoscopic-assisted en bloc resection.


RESULTS
Elderly male patient presented with an isolated abdominal wall incisional recurrence 18 mo after gastric resection and adjuvant imatinib mesylate therapy for a high-grade GIST.


CONCLUSIONS
Complete resection of gastrointestinal stromal tumors followed by imatinib therapy may alter the extent of recurrence.
Cunningham
Steven C
SC
Division of Surgical Oncology, Department of Surgery, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201, USA.
Shibata
David
D
Volpe
Carmine
C
D034861:Abdominal Wall / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006801:Humans; D000068877:Imatinib Mesylate; D010535:Laparoscopy / Q000009:adverse effects*; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010879:Piperazines / Q000627:therapeutic use; D011183:Postoperative Complications; D011743:Pyrimidines / Q000627:therapeutic use; D017154:Stromal Cells; D013529:Surgical Wound Dehiscence
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate