Two-component signal-transduction systems in budding yeast MAP a different pathway?
Until recently, two-component signal-transduction pathways were thought to be exclusively found in bacteria. Some eukaryotic examples have now been characterized but, at least in the budding yeast Saccharomyces cerevisiae, it appears that this type of signal-transduction pathway is not utilized as extensively as in bacteria. Further, the few eukaryotic examples described suggest that two-component signal-transduction pathways might not be freestanding, as in prokaryotes, but might effect gene expression by regulating eukaryotic mitogen-activated protein (MAP) kinase pathways.
Morgan
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BA
Division of Yeast Genetics at the National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
Bouquin
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N
Johnston
L H
LH