title: [Effect of space flight on yield of Monascus purpureus].
abstract: OBJECTIVE
  To select high Lovastatin-producing microbial breed by space flight.
  
  
  METHODS
  Monascus purpureus species was carried into space by the recoverable spaceship, "Shenzhou 3". After flight, the strain was rejuvenized, segregated and selected. The content of Lovastatin produced in the solid fermentation was examined.
  
  
  RESULTS
  Mutants with high productivity of Lovastatin were obtained. A series of tests showed that the acquired character of the mutants was stable.
  
  
  CONCLUSIONS
  Space flight is an effective method for the selection of fine strains.
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Shen-yi
authors.initials: SY
authors.lastname: Xie
authors.forename: Guang-ming
authors.initials: GM
authors.lastname: Zhang
authors.forename: Shen-meng
authors.initials: SM
authors.lastname: Xie
mesh_terms: D004783:Environmental Microbiology; D008148:Lovastatin / Q000235:genetics / Q000378:metabolism*; D032741:Monascus / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D009154:Mutation; D013026:Space Flight; D014893:Weightlessness
chemical_list: D008148:Lovastatin