Transient receptor potential ion channels and animal sensation: lessons from Drosophila functional research.
Ion channels of the transient receptor potential (TRP) superfamily are non-selective cationic channels with six transmembrane domains. The TRP channel made its first debut as a light-gated Ca2+ channel in Drosophila. Recently, research on animal sensation in Drosophila disclosed other members of the TRP family that are required for touch sensation and hearing as well as the sensation of painful stimuli.
Kim
Changsoo
C
Department of Genetics, Hanwha Chemical Co. RD Center, Sinsung-Dong, Yusung-Gu, Daejeon 305-345, Korea. changgk2001@hanmail.net
D000818:Animals; D015220:Calcium Channels / Q000737:chemistry / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D004330:Drosophila / Q000502:physiology*; D029721:Drosophila Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology*; D015640:Ion Channel Gating; D007473:Ion Channels / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D012106:Research; D012677:Sensation; D015398:Signal Transduction; D050051:Transient Receptor Potential Channels
D015220:Calcium Channels; D029721:Drosophila Proteins; D007473:Ion Channels; D050051:Transient Receptor Potential Channels; C063169:trp protein, Drosophila