ADL2a, like ADL2b, is involved in the control of higher plant mitochondrial morphology.
A mitochondrial-GFP construct was used to tag mitochondria fluorescently in a T-DNA knockout line for the Arabidopsis dynamin ADL2a. Visualization of mitochondria in vivo demonstrated that disruption of ADL2a affected mitochondrial morphology. Mitochondria in the mutant had a complex morphology; occasionally large spherical organelles could be seen, but, more frequently, the mitochondria adopted a tubular morphology with many constrictions along their length. Mitochondria in the mutant also frequently possessed long protuberances that were named matrixules, extending to many micrometres in length.
Logan
David C
DC
Sir Harold Mitchell Building, School of Biology, University of St Andrews, St Andrews, Fife KY16 9TH, UK. david.logan@st-and.ac.uk
Scott
Iain
I
Tobin
Alyson K
AK
D017360:Arabidopsis / Q000201:enzymology* / Q000648:ultrastructure; D029681:Arabidopsis Proteins / Q000235:genetics*; D001483:Base Sequence; D017931:DNA Primers; D020558:GTP Phosphohydrolases / Q000235:genetics*; D017353:Gene Deletion; D008928:Mitochondria / Q000648:ultrastructure*; D030821:Plants, Genetically Modified; D016133:Polymerase Chain Reaction
C114648:ADL2 protein, Arabidopsis; D029681:Arabidopsis Proteins; D017931:DNA Primers; C456288:ADL2b protein, Arabidopsis; D020558:GTP Phosphohydrolases