title: Primitive leiomyosarcoma of the breast: case report and review of the literature.
abstract: Sarcomas of the breast account for under 1% of breast tumours. Leiomyosarcomas are less common, being a subgroup of sarcomas of the breast. Only 23 cases with immunohistochemical or electron microscopy confirmation are reported in the literature. The case of a 58-year-old woman with a leiomyosarcoma 4 cm in diameter in the upper external quadrant of the right breast is presented. Mammography and sonography were compatible with a fibroadenoma or phylloides tumour, and fine-needle aspiration (FNA) suggested medullary carcinoma. The patient underwent a Madden-type modified radical mastectomy and axillary lymphadenectomy. Adjuvant chemotherapy was implemented with Adriamycin (four cycles of 21 days). One year after surgery the patient is tumour free.
authors.affiliation: Department of Surgery, Virgen de la Arrixaca University Hospital, Servicio de Cirugia General, 3a planta Ctra. Cartagena s/n, 30120 El Palmar (Murcia), Spain. vins@mundofree.com
authors.forename: V
authors.initials: V
authors.lastname: Munitiz
authors.forename: A
authors.initials: A
authors.lastname: Rios
authors.forename: J
authors.initials: J
authors.lastname: Canovas
authors.forename: B
authors.initials: B
authors.lastname: Ferri
authors.forename: J
authors.initials: J
authors.lastname: Sola
authors.forename: P
authors.initials: P
authors.lastname: Canovas
authors.forename: J
authors.initials: J
authors.lastname: Illana
authors.forename: P
authors.initials: P
authors.lastname: Parrilla
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008408:Mastectomy; D008875:Middle Aged