title: Necrolytic migratory erythema: case report and clinical review.
abstract: BACKGROUND
  Necrolytic Migratory Erythema (NME) is a rarely encountered dermatologic condition. It is the characteristic feature of a paraneoplastic syndrome associated with neuroendocrine pancreatic tumors. A case of NME initially diagnosed and treated as psoriasis is reviewed. A review of the current literature regarding NME is also included.
  
  
  OBJECTIVE
  The purpose of this report is to familiarize dermatologists with a rare and potentially fatal disorder. Early recognition of NME can lead to possible cure, while delayed identification of the disease is associated with metastatic disease and a poor prognosis for the patient.
  
  
  CONCLUSIONS
  When evaluating the patient who presents with a dermatitis and weight loss, it is important to exercise great caution. The differential diagnosis should be re-evaluated in a disease that is not responsive to first-line therapy before further treatment is considered.
authors.affiliation: Department of Medicine, University of Toronto, Ontario, Canada. dnadam@interchange.ubc.ca
authors.forename: David N
authors.initials: DN
authors.lastname: Adam
authors.forename: Paul D
authors.initials: PD
authors.lastname: Cohen
authors.forename: Danny
authors.initials: D
authors.lastname: Ghazarian
mesh_terms: D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D004890:Erythema / Q000188:drug therapy* / Q000209:etiology; D005935:Glucagonoma / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D015282:Octreotide / Q000627:therapeutic use; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D010257:Paraneoplastic Syndromes / Q000188:drug therapy* / Q000209:etiology; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide