CMV enteritis causing ileal perforation in underlying lupus enteritis.
We report a case of cytomegalovirus (CMV) enteritis in a 31 year-old -woman with lupus enteritis. In August 2002 the patient complained of severe abdominal pain. An abdominopelvic CT scan at the time showed free air in the peritoneal cavity and wall thickening of the ileal loop. She was diagnosed as having panperitonitis due to an ileal perforation, and underwent an emergency laparotomy. The surgical specimen revealed CMV inclusion bodies in the infarcted lesion. Her symptoms improved following the initiation of ganciclovir therapy. To the best of our knowledge, this is the first report in the English literature of an ileal perforation due to CMV infection in a patient with lupus enteritis.
Bang
Seungmin
S
Department of Internal Medicine, Institute for Immunology and Immunological Disease, BK 21 Project for Medical Science, Yonsei University College of Medicine, Shinchon-dong 134, Seodaemoon-gu, 120-752, Seoul, Korea.
Park
Yong-Beom
YB
Kang
Byung Seung
BS
Park
Min Chan
MC
Hwang
Min Ho
MH
Kim
Ho Keun
HK
Lee
Soo-Kon
SK
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000302:isolation & purification* / Q000472:pathogenicity; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004359:Drug Therapy, Combination; D004751:Enteritis / Q000209:etiology* / Q000473:pathology; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007082:Ileum / Q000473:pathology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine; D015774:Ganciclovir