Quantitative analysis of human salivary glucose by gas chromatography-mass spectrometry.
A reference analytic methodology was developed for the determination of human salivary glucose concentration. The technique involves the glucose derivatization with acetic anhydride and subsequent analysis of glucose penta-acetylated by gas chromatography combined with mass spectrometry. Glucose concentration in the biological fluid depends on the physiological status of the donor.
Di Gioia
Maria Luisa
ML
Dipartimento di Scienze Farmaceutiche, Università degli Studi della Calabria, Arcavacata di Rende, Italy.
Leggio
Antonella
A
Le Pera
Adolfo
A
Liguori
Angelo
A
Napoli
Anna
A
Siciliano
Carlo
C
Sindona
Giovanni
G
D002940:Circadian Rhythm; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D005947:Glucose / Q000032:analysis*; D006801:Humans; D012463:Saliva / Q000737:chemistry*; D012680:Sensitivity and Specificity; D014851:Wakefulness
D005947:Glucose