Predictors of tonsillar tissue HIV-1 viral burden at baseline and after 1 year of antiretroviral therapy.
In 81 antiretroviral-navie HIV-1 chronic-infected patients, we found a correlation among tonsillar tissue viral load, and virological and immunological measures in blood at baseline. No correlation was observed after 1 year of antiretroviral therapy. A protease inhibitor-containing regimen was the best predictor of good tonsillar tissue virological response.
Navarrete
Pilar
P
Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Faculty of Medicine, University of Barcelona, Barcelona, Spain.
Morente
Vanessa
V
García
Felipe
F
Alós
Lluçia
L
Arnedo
Mireia
M
Plana
Montserrat
M
Gil
Cristina
C
Caballero
Miguel
M
Miró
José M
JM
Martínez
Esteban
E
Fumero
Emilio
E
Castro
Pedro
P
Blanco
José L
JL
Mallolas
Josep
J
Blanch
José L
JL
Cruceta
Anna
A
Mestre
Gabriel
G
Pumarola
Tomás
T
Gallart
Teresa
T
Gatell
José M
JM
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000821:virology; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D014066:Palatine Tonsil / Q000821:virology*; D019562:Viral Load; D014766:Viremia / Q000821:virology
D019380:Anti-HIV Agents