Is there evidence of a sphincter system in Wharton's duct? Etiological factors related to sialolith formation.
The exact cause of the formation of sialoliths is unknown. Detailed knowledge of the pathogenesis of sialolithiasis is necessary to define new therapeutic procedures. The possible presence of a sphincter system in Wharton's duct has been described frequently in the context of diagnostic sialendoscopy. Serial histological examination of the entire Wharton's duct in four samples revealed no anatomical correlation for the presence of a sphincter. Secretory disturbances and viscous secretions as well as microlith formation and ductal obstruction cannot fully explain the genesis of sialoliths. The coaction of those factors with participation of bacteria leads to the development of sialoliths.
Teymoortash
Afshin
A
Department of Otolaryngology, Head and Neck Surgery, Philipps University, Marburg 35037, Germany. teymoort@med.uni-marburg.de
Ramaswamy
Annette
A
Werner
Jochen Alfred
JA
D000368:Aged; D001424:Bacterial Infections / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism; D018987:Salivary Ducts / Q000033:anatomy & histology*; D015494:Salivary Gland Calculi / Q000209:etiology* / Q000473:pathology; D013363:Submandibular Gland / Q000033:anatomy & histology*; D013364:Submandibular Gland Diseases / Q000209:etiology* / Q000473:pathology