Facile palladium-catalysed synthesis of 1-aryl-1H-indazoles from 2-bromobenzaldehydes and arylhydrazines.
2-Bromobenzaldehydes react with arylhydrazines in toluene at 100 [degree]C in the presence of a catalytic amount of a palladium catalyst and phosphorus chelating ligands such as 1,1[prime or minute]-bis(diphenylphosphino)ferrocene and 1,3-bis(diphenylphosphino)propane along with NaO-t-Bu to afford 1-aryl-1H-indazoles in good yields.
Cho
Chan Sik
CS
Research Institute of Industrial Technology, Kyungpook National University, Daegu 702-701, Korea.
Lim
Dong Kwon
DK
Heo
Nam Ho
NH
Kim
Tae-Jeong
TJ
Shim
Sang Chul
SC