title: Inflammatory myopathy in a patient with cutaneous findings of pityriasis rubra pilaris: a case of Wong's dermatomyositis.
abstract: We report the case of a 46-year-old woman presenting cutaneous lesions similar to those of pityriasis rubra pilaris, characterized by diffuse scaling erythroderma and palmoplantar keratoderma; skin biopsy showed follicular hyperkeratosis with a perivascular lymphocytic infiltrate. One year later she developed an inflammatory myopathy; on the basis of clinical features, a diagnosis of dermatomyositis was made. Treatment with prednisone and hydroxychloroquine led to complete control of the cutaneous and muscular involvement, which was maintained during prednisone tapering.
authors.affiliation: Department of Rheumatology, IRCCS Policlinico, San Matteo Hospital, University of Pavia, Piazzale Golgi 2, 27100, Pavia, Italy. caporali@smatteo.pv.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Caporali
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Cavagna
authors.forename: Mario
authors.initials: M
authors.lastname: Bellosta
authors.forename: Laura
authors.initials: L
authors.lastname: Bogliolo
authors.forename: Carlomaurizio
authors.initials: C
authors.lastname: Montecucco
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D007645:Keratoderma, Palmoplantar / Q000209:etiology / Q000473:pathology; D008875:Middle Aged; D010916:Pityriasis Rubra Pilaris / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D006886:Hydroxychloroquine; D011241:Prednisone