title: Simultaneous supraventricular tachycardias in both fetuses of a twin gestation.
abstract: BACKGROUND
  Fetal supraventricular tachycardia confers an increased risk of cardiac failure, hydrops, and eventual intrauterine death. Although protocols for prenatal anti-arrhythmic treatment are now well established, few published reports discuss this condition in the setting of multiple pregnancies.
  
  
  METHODS
  A 20-year-old primigravida woman with a twin pregnancy presented at 31 weeks of gestation for routine obstetrical check-up which revealed simultaneous supraventricular tachycardia in both fetuses. She was treated with oral digoxin, resulting in successful cardioversion in both of the fetuses, which was maintained until they were delivered by caesarian section at 38 weeks gestation. However, several hours after birth, tachyarrhythmias recurred in each of the infants. Combined disopyramide therapy with digoxin was necessary to control their heart rates.
  
  
  CONCLUSIONS
  The treatment of arrhythmia in fetuses of a multiple gestation presents unique issues, particularly when diagnosed prior to fetal lung maturity.
authors.affiliation: Department of Pediatrics, Nippon Medical School, Tokyo, Japan. shima-p@nms.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Shima
authors.forename: Chiaki
authors.initials: C
authors.lastname: Baba
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fujita
authors.forename: Miho
authors.initials: M
authors.lastname: Kanoh
authors.forename: Miki
authors.initials: M
authors.lastname: Watanabe
authors.forename: Shunichi
authors.initials: S
authors.lastname: Ogawa
authors.forename: Rieko
authors.initials: R
authors.lastname: Kawase
authors.forename: Sumio
authors.initials: S
authors.lastname: Shin
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004077:Digoxin / Q000008:administration & dosage / Q000627:therapeutic use; D004206:Disopyramide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005315:Fetal Diseases / Q000188:drug therapy; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012008:Recurrence; D013617:Tachycardia, Supraventricular / Q000188:drug therapy / Q000503:physiopathology; D014427:Twins
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D004206:Disopyramide