title: Permanent-wave dermatitis: contact allergy to cysteamine hydrochloride.
abstract: Cysteamine hydrochloride (CHC) is a newly recognized sensitizer found in permanent-wave solutions. We report the case of a hairdresser who was found to be allergic to CHC. Our allergic patient was patch-tested to various chemicals found in permanent-wave solutions, including CHC (1.0% in petrolatum). Patch-test reactions were positive to CHC, glyceryl thioglycolate, diglyceryl thioglycolate, p-phenylenediamine (PPD), and PPD through a piece of latex glove. Sixty-four controls to CHC (1.0% in petrolatum) had negative results. Household-weight latex gloves were protective against CHC allergy. Persons with CHC-waved hair were not allergic. CHC contained in "neutral" permanent-wave preparations has been used in American beauty salons since 1993. We briefly discuss the introduction and significance of CHC in permanent waves.
authors.affiliation: Department of Dermatology, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Maeran C
authors.initials: MC
authors.lastname: Landers
authors.forename: Sandra
authors.initials: S
authors.lastname: Law
authors.forename: Frances J
authors.initials: FJ
authors.lastname: Storrs
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects*; D003543:Cysteamine / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006203:Hair Preparations / Q000009:adverse effects*; D006229:Hand Dermatoses / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D010328:Patch Tests
chemical_list: D000485:Allergens; D006203:Hair Preparations; D003543:Cysteamine