title: Recommended and actual lepirudin doses in patients with renal insufficiency.
authors.affiliation: Department of Pharmacy, UMass Memorial Medical Center, 55 Lake Avenue North, Worcester, MA 01655, USA. saxers@ummhc.org
authors.forename: Sarah B
authors.initials: SB
authors.lastname: Saxer
authors.forename: Brian S
authors.initials: BS
authors.lastname: Smith
authors.forename: Pritesh J
authors.initials: PJ
authors.lastname: Gandhi
authors.forename: Gary R
authors.initials: GR
authors.lastname: Tataronis
authors.forename: Susan A
authors.initials: SA
authors.lastname: Krikorian
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000009:adverse effects; D006629:Hirudins / Q000008:administration & dosage* / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D011994:Recombinant Proteins / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D051437:Renal Insufficiency / Q000150:complications*; D013921:Thrombocytopenia / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy; D014481:United States
chemical_list: D000925:Anticoagulants; D006629:Hirudins; D011994:Recombinant Proteins; D006493:Heparin; C083544:lepirudin