title: Hypothalamic ganglioglioma treated by temporal lobectomy. Case report and review of the literature.
abstract: The authors report the case of a hypothalamic ganglioglioma with left-sided temporal lobe extension in an 8-year-old girl who presented with seizures. Other cases of ganglioglioma involving the hypothalamus have been reported in the literature; however, this site of origin is exceedingly rare and worthy of report. Treatment involved medial temporal lobectomy with the hypothalamic component of the tumor remaining untouched. The patient recovered postoperatively with no neurological deficits and was seizure free at 12 months. Neither radio- nor chemotherapy was recommended because of the tumor histology, location, and the patient's age. The authors recommend follow up and surgical treatment for possible tumor recurrence. The prognosis for hypothalamic ganglioglioma is unknown.
authors.affiliation: Division of Neurosurgery, University of California, San Diego, San Diego Medical Center, 92103-8893, USA. hearyan@ucsd.edu
authors.forename: Henry E
authors.initials: HE
authors.lastname: Aryan
authors.forename: Hal S
authors.initials: HS
authors.lastname: Meltzer
authors.forename: Michael L
authors.initials: ML
authors.lastname: Levy
authors.forename: Bartek J
authors.initials: BJ
authors.lastname: Szkandera
authors.forename: Derek A
authors.initials: DA
authors.lastname: Bruce
mesh_terms: D038481:Anterior Temporal Lobectomy; D002648:Child; D004292:Dominance, Cerebral / Q000502:physiology; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D018303:Ganglioglioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D007031:Hypothalamus / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery