title: Galanthamine pattern in Narcissus confusus plants.
abstract: Galanthamine is an Amaryllidaceae-type alkaloid with acetylcholinesterase inhibitory activity which is used in the treatment of Alzheimer's disease. The distribution of galanthamine and four other alkaloids in different organs of Narcissus confusus plants, as well as the variations occurring during the ontogenic cycle of this plant species, was studied. The five alkaloids were found to be present in all the organs at every stage, with the exception of haemanthamine in senescent flowers. The highest amount of alkaloids occurred in the bulb at the emerging stage, galanthamine being the most abundant, reaching a concentration of up to 2.5 % referred to dry weight.
authors.affiliation: Departament de Productes Naturals, Biologia Vegetal i Edafologia, Facultat de Farmàcia, Universitat de Barcelona, Barcelona, Catalunya, Spain.
authors.forename: Susana
authors.initials: S
authors.lastname: López
authors.forename: Jaume
authors.initials: J
authors.lastname: Bastida
authors.forename: Francesc
authors.initials: F
authors.lastname: Viladomat
authors.forename: Carles
authors.initials: C
authors.lastname: Codina
mesh_terms: D000470:Alkaloids / Q000096:biosynthesis* / Q000737:chemistry; D005702:Galantamine / Q000096:biosynthesis* / Q000737:chemistry; D006801:Humans; D031427:Narcissus / Q000254:growth & development / Q000378:metabolism*; D008517:Phytotherapy
chemical_list: D000470:Alkaloids; D005702:Galantamine