The potential of bone marrow cells to orchestrate homeostasis and healing in skin.
Bone marrow derived cells play a major role in the maintenance and repair of many tissues, mostly by the delivering of a variety of inflammatory cells. Recent evidence however suggests that bone marrow may also supply cellular substrate for rebuilding non-hematopoietic tissues following injury. This discussion addresses the potential role of bone marrow to provide cells to the skin for rebuilding of skin structures following injury and for skin maintenance.
Badiavas
Evangelos V
EV
Department of Dermatology and Skin Surgery, Roger Williams Medical Center, Boston University School of Medicine, Providence, RI 02908, USA. evb@bu.edu
D001854:Bone Marrow Cells / Q000502:physiology*; D016026:Bone Marrow Transplantation; D006706:Homeostasis; D006801:Humans; D012867:Skin / Q000473:pathology*; D014945:Wound Healing