title: Weight gain and improvement with quetiapine in bipolar I disorder: a case report.
abstract: Observations made with quetiapine (QUET) in this case give clues for some aspects of its use for patients with bipolar disorder. Weight gain (11 kg; 16.6% increase in 21 weeks) and improvement in manic symptoms occurred after QUET add-on to lithium (Li). Patient's mood improved after QUET add-on without causing extrapyramidal symptoms (EPS), while QUET was discontinued due to weight gain. Short-term QUET add-on to Li may help mood stabilization in bipolar I disorder. Weight changes must be observed carefully.
authors.affiliation: Department of Psychiatry, Inonu University Medical School, Malatya, Turkey. eozcan@inonu.edu.tr
authors.forename: M Erkan
authors.initials: ME
authors.lastname: Ozcan
authors.forename: Burhanettin
authors.initials: B
authors.lastname: Kaya
authors.forename: Ruhcan
authors.initials: R
authors.lastname: Polat
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000503:physiopathology*; D003987:Dibenzothiazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D000069348:Quetiapine Fumarate; D015430:Weight Gain / Q000187:drug effects
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate