Pruritus in a patient with advanced cancer successfully treated with continuous infusion of granisetron.
We present a case of a patient with advanced cancer affected by severe pruritus not related with cholestasis and/or opioid treatment successfully treated with subcutaneous continuous infusion of granisetron (3 mg/24 h diluted in normal saline via a disposable elastomeric infusion device). Confirmatory studies with a control group are warranted to confirm these preliminary results.
Porzio
Giampiero
G
Supportive Care and Rehabilitation Unit, Medical Oncology Department, University of L'Aquila, L'Aquila, Italy. porzio1@interfree.it
Aielli
Federica
F
Narducci
Filomena
F
Cannita
Katia
K
Piccolo
Domenico
D
Marchetti
Paolo
P
D000368:Aged; D005260:Female; D017829:Granisetron / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D009369:Neoplasms / Q000150:complications* / Q000503:physiopathology; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D012702:Serotonin Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*
D017829:Granisetron; D012702:Serotonin Antagonists