title: Efficient synthesis of exo-olefinated deoxoartemisinin derivatives by Ramberg-Bäcklund rearrangement.
abstract: 10-exo-Bromoalkylidene- and benzylidenedeoxoartemisinins were synthesized from corresponding 10-alkanesulfonyldihydroartemisinin and 10-phenylmethanesulfonyldihydroartemisinin using a highly efficient, mild, and simple Ramberg-Bäcklund rearrangement.
authors.affiliation: Department of Chemistry, Yonsei University, Wonju 220-710, South Korea.
authors.forename: Sangtae
authors.initials: S
authors.lastname: Oh
authors.forename: In Howa
authors.initials: IH
authors.lastname: Jeong
authors.forename: Seokjoon
authors.initials: S
authors.lastname: Lee
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000962:Antimalarials / Q000138:chemical synthesis; D037621:Artemisinins / Q000138:chemical synthesis* / Q000737:chemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000962:Antimalarials; D037621:Artemisinins; D012717:Sesquiterpenes; C063801:deoxoartemisinin