A simple copper salt catalysed the coupling of imidazole with arylboronic acids in protic solvent.
In the presence of a catalytic amount of a simple copper salt, the coupling of imidazole with arylboronic acids was performed in methanol to give corresponding N-arylimidazoles in almost quantitative yields; this coupling reaction could also be performed in aqueous solutions to give N-arylimidazoles in excellent yields.
Lan
Jing-Bo
JB
Department of Chemistry, Sichuan University, Chengdu 610064, P. R. China.
Chen
Li
L
Yu
Xiao-Qi
XQ
You
Jing-Song
JS
Xie
Ru-Gang
RG