title: Human herpes virus-8-negative primary effusion lymphoma in a patient with common variable immunodeficiency.
abstract: Primary effusion lymphoma (PEL) is a newly described high-grade B cell lymphoma developing in association with human herpes virus type 8 (HHV-8) in human immunodeficiency virus (HIV)-infecting individuals. Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by reduced serum immunoglobulin and heterogeneous clinical features. The risk of cancer in CVID patients is increased. Here, we describe a PEL that developed in the pleural and pericardial cavities of an HIV-negative and HHV-8-negative patient with CVID.
authors.affiliation: Departament of Medicine, Sumitomo-Besshi Hospital, 3-1 Ojicho, Niihama, Ehime 792-0008, Japan. fwpg0506@mb.infoweb.ne.jp
authors.forename: Akiko
authors.initials: A
authors.lastname: Hisamoto
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Yamane
authors.forename: Akio
authors.initials: A
authors.lastname: Hiraki
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Maeda
authors.forename: Nobuharu
authors.initials: N
authors.lastname: Fujii
authors.forename: Kenji
authors.initials: K
authors.lastname: Sasaki
authors.forename: Toshitugu
authors.initials: T
authors.lastname: Miyake
authors.forename: Takashi
authors.initials: T
authors.lastname: Sasaki
authors.forename: Tohru
authors.initials: T
authors.lastname: Nakamura
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kiura
authors.forename: Mitsune
authors.initials: M
authors.lastname: Tanimoto
authors.forename: Haruhito
authors.initials: H
authors.lastname: Kamei
mesh_terms: D017074:Common Variable Immunodeficiency / Q000175:diagnosis*; D005260:Female; D018023:HIV Seronegativity; D006566:Herpesviridae Infections / Q000821:virology*; D019288:Herpesvirus 8, Human; D006801:Humans; D007564:Japan; D008223:Lymphoma / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D016066:Pleural Effusion, Malignant / Q000209:etiology* / Q000473:pathology; D010997:Pleural Neoplasms / Q000209:etiology* / Q000473:pathology