title: Lovastatin inhibits its own synthesis in Aspergillus terreus.
abstract: Lovastatin suppresses its own synthesis in the microfungus Aspergillus terreus. The inhibitory effect was documented by spiking identical batch cultures with pure lovastatin (0, 50, 100 and 250 mg/l) 24 h after initiation from spores.
authors.affiliation: Department of Chemical Engineering, University of Almería, 04120, Almería, Spain. jlcasas@ual.es
authors.forename: J L
authors.initials: JL
authors.lastname: Casas López
authors.forename: E M
authors.initials: EM
authors.lastname: Rodríguez Porcel
authors.forename: M A
authors.initials: MA
authors.lastname: Vilches Ferrón
authors.forename: J A
authors.initials: JA
authors.lastname: Sánchez Pérez
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández Sevilla
authors.forename: Y
authors.initials: Y
authors.lastname: Chisti
mesh_terms: D000970:Antineoplastic Agents / Q000378:metabolism* / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects / Q000378:metabolism*; D001709:Biotechnology; D025461:Feedback, Physiological; D005285:Fermentation; D008148:Lovastatin / Q000096:biosynthesis* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D008148:Lovastatin