title: Intact mutS in laboratory-derived and clinical glycopeptide-intermediate Staphylococcus aureus strains.
abstract: The mutS gene of the methyl-directed mismatch repair system was sequenced in 10 parent and glycopeptide-intermediate Staphylococcus aureus strains. The mutS gene was intact in all strains studied. Hence, mutations in this gene had played no role in the development of vancomycin resistance in these strains.
authors.affiliation: Microbiology Group, Department of Biological Sciences, Illinois State University, Normal, Illinois 61790-4120, USA.
authors.forename: Arunachalam
authors.initials: A
authors.lastname: Muthaiyan
authors.forename: Radheshyam K
authors.initials: RK
authors.lastname: Jayaswal
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Wilkinson
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D020137:Base Pair Mismatch / Q000235:genetics; D001483:Base Sequence; D004260:DNA Repair / Q000235:genetics; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D006020:Glycopeptides / Q000235:genetics*; D016106:Methicillin Resistance / Q000235:genetics; D008969:Molecular Sequence Data; D051719:MutS DNA Mismatch-Binding Protein; D009154:Mutation / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development; D020713:Vancomycin Resistance / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; D006020:Glycopeptides; D000251:Adenosine Triphosphatases; D051719:MutS DNA Mismatch-Binding Protein