Cyclobutanes from Combretum albopunctatum.
A dichloromethane extract of the aerial parts of Combretum albopunctatum Suesseng afforded five phenolic compounds-three known flavonoids and two novel cyclobutane chalcone dimers. The chemical structures were determined by standard spectroscopic techniques and the structure and relative stereochemistry of one chalcone dimer, rel-(1 alpha,2 beta)-di-(2,6-dimethoxy-4-hydroxy)-benzoyl-rel-(3 alpha,4 beta)-diphenylcyclobutane, were confirmed by single crystal X-ray diffraction.
Katerere
David R
DR
Department of Pharmaceutical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, UK.
Gray
Alexander I
AI
Kennedy
Alan R
AR
Nash
Robert J
RJ
Waigh
Roger D
RD
D002599:Chalcone / Q000031:analogs & derivatives / Q000302:isolation & purification; D029765:Combretum / Q000737:chemistry*; D003503:Cyclobutanes / Q000737:chemistry* / Q000302:isolation & purification*; D019281:Dimerization; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D013237:Stereoisomerism; D014961:X-Ray Diffraction
D003503:Cyclobutanes; D010936:Plant Extracts; D002599:Chalcone