title: Prospective, randomized trial of diclofenac and ketorolac after refractive surgery.
abstract: OBJECTIVE
  To compare the effectiveness of diclofenac and ketorolac in relieving corneal pain after refractive surgery, and determine if there is a difference in stinging on instillation.
  
  
  METHODS
  Thirty patients were randomized prospectively to postoperative diclofenac in one eye and ketorolac in the other. Patients and surgeon did not know which medications were used. Ocular postoperative pain and discomfort on instillation of medication were measured after radial keratotomy with a visual analog scale and a questionnaire.
  
  
  RESULTS
  Both medications were highly effective in relieving pain. There was no significant difference in pain relief, or stinging on instillation (P = .29).
  
  
  CONCLUSIONS
  There was no statistical difference in the effectiveness of the medications on pain relief, or in stinging on instillation.
authors.affiliation: Loma Linda University, Department of Ophthalmology, Loma Linda, CA 92354, USA.
authors.forename: Julio
authors.initials: J
authors.lastname: Narváez
authors.forename: Peter
authors.initials: P
authors.lastname: Krall
authors.forename: Tom S
authors.initials: TS
authors.lastname: Tooma
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D003315:Cornea / Q000187:drug effects / Q000601:surgery; D004008:Diclofenac / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007646:Keratotomy, Radial; D020910:Ketorolac / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D010149:Postoperative Pain / Q000188:drug therapy*; D011446:Prospective Studies
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009883:Ophthalmic Solutions; D004008:Diclofenac; D020910:Ketorolac