title: Acute renal failure on immune reconstitution in an HIV-positive patient with miliary tuberculosis.
abstract: Immune reconstitution syndrome following HAART in human immunodeficiency virus (HIV)-infected patients is characterized by inflammatory worsening of organ functions despite improvement in HIV surrogate markers of HIV infection. We describe a patient with miliary tuberculosis and urinary shedding of acid fast bacilli who developed acute renal failure 8 weeks after initiation of antituberculosis therapy and 6 weeks after initiation of HAART. The diagnostic workup and further course of disease implicated immune reconstitution syndrome as the cause of acute renal failure.
authors.affiliation: Division of Transplantation Immunology and Nephrology, University Hospitals Basel, Basel, Switzerland.
authors.forename: Andreas W
authors.initials: AW
authors.lastname: Jehle
authors.forename: Nina
authors.initials: N
authors.lastname: Khanna
authors.forename: Jörg-Peter
authors.initials: JP
authors.lastname: Sigle
authors.forename: Katharina
authors.initials: K
authors.lastname: Glatz-Krieger
authors.forename: Manuel
authors.initials: M
authors.lastname: Battegay
authors.forename: Jürg
authors.initials: J
authors.lastname: Steiger
authors.forename: Michael
authors.initials: M
authors.lastname: Dickenmann
authors.forename: Hans H
authors.initials: HH
authors.lastname: Hirsch
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000276:immunology*; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014391:Tuberculosis, Miliary / Q000276:immunology*