[Effects of anxiolytic agents on some immunologic parameters of the stressed rats].
Repeated stress under forced swim test conditions suppresses most of the immunological characteristics in rats. Diazepam and melatonin (both in a dose of 0.1 mg/kg), while not changing significantly the immunological state of intact animals, decrease the stress-induced shifts. The immunotropic effect of melatonin is much more pronounced than that of diazepam.
Arushanian
E B
EB
Pharmacology Department, State Medical Academy, Ministry of Public Health of the Russian Federation, ul. Mira 310, Stavropol, 355024 Russia.
Baturina
M V
MV
Beĭer
E V
EV
Kuz'mina
E M
EM
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D003975:Diazepam / Q000494:pharmacology*; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D051381:Rats; D013315:Stress, Psychological / Q000276:immunology*
D014151:Anti-Anxiety Agents; D008550:Melatonin; D003975:Diazepam