title: [Antimicrobial resistance of Helicobacter pylori: clinical and molecular aspects].
abstract: Helicobacter pylori is a relevant pathogen for gastroduodenal diseases in human beings. Although its eradication often improves gastroduodenal diseases, H pylori is acquiring an elevated rate of resistance to various antimicrobials, such as metronidazole, clarithromycin, tetracycline and amoxicillin. Multi-drug resistance is a major problem to select the appropriate treatment of infectious diseases. To improve our understanding on the complexity of the problem, in this article we review the resistance mechanisms and give an update on H pylori antimicrobial resistance.
authors.affiliation: Facultad de Ciencias, Universidad de Chile.
authors.forename: Cristián
authors.initials: C
authors.lastname: Vallejos
authors.forename: Oscar
authors.initials: O
authors.lastname: Cerda
authors.forename: Manuel
authors.initials: M
authors.lastname: Valenzuela
authors.forename: Héctor
authors.initials: H
authors.lastname: Toledo
mesh_terms: D000658:Amoxicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D013754:Tetracyclines / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013754:Tetracyclines; D008795:Metronidazole; D000658:Amoxicillin