title: Loss of left bundle branch block following biventricular pacing therapy for heart failure: evidence for electrical remodeling?
abstract: Cardiac resynchronization therapy has been proven to improve symptoms and indices of left ventricular function in patients with heart failure and intraventricular conduction delays. We present a case of a patient with New York Association Class III heart failure and left bundle branch block, who received a biventricular pacemaker in order to achieve cardiac resynchronization. Her symptoms improved markedly, as did left ventricular ejection fraction and dimensions. In addition, her intrinsic QRS duration normalized. This may represent a salutory effect of biventricular pacing on electrical remodeling.
authors.affiliation: Department of Medicine, Division of Cardiology, Columbia-Presbyterian Medical Center, Columbia University, New York, USA. JMD11@Columbia.edu
authors.forename: José
authors.initials: J
authors.lastname: Dizon
authors.forename: Evelyn
authors.initials: E
authors.lastname: Horn
authors.forename: John
authors.initials: J
authors.lastname: Neglia
authors.forename: Norma
authors.initials: N
authors.lastname: Medina
authors.forename: Hasan
authors.initials: H
authors.lastname: Garan
mesh_terms: D002037:Bundle-Branch Block / Q000150:complications / Q000503:physiopathology*; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D010138:Pacemaker, Artificial; D013318:Stroke Volume; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling