title: A solitary lesion of talus with mixed sclerotic and lytic changes: Rosai-Dorfman disease of 25 years' duration.
abstract: Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is an unusual form of histiocytic disorder predominantly affecting children and young adults. Bone lesions are infrequent. We describe a 63-year-old woman with a solitary lesion of the talus which was misdiagnosed for 25 years. The patient never had adenopathy or other organ involvement. The radiographic findings were a mixture of sclerotic and lytic changes, an extremely rare and unusual presentation of the disease.
authors.affiliation: Department of Radiology, New York Methodist Hospital Affiliated with Weill Medical College of Cornell University, 506 Sixth Street, Brooklyn, NY 11215, USA. fikrya@hotmail.com
authors.forename: Ibrahim Fikry
authors.initials: IF
authors.lastname: Abdelwahab
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Klein
authors.forename: Dempsey S
authors.initials: DS
authors.lastname: Springfield
authors.forename: George
authors.initials: G
authors.lastname: Hermann
mesh_terms: D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013628:Talus / Q000473:pathology; D013997:Time Factors