ROSO: optimizing oligonucleotide probes for microarrays.
ROSO is software to design optimal oligonucleotide probe sets for microarrays. Selected probes show no significant cross-hybridization, no stable secondary structures and their Tm are chosen to minimize the Tm variability of the probe set.


BACKGROUND
The program is available on the internet. Sources are freely available, for non-profit use, on request to the authors.


BACKGROUND
http://pbil.univ-lyon1.fr/roso
Reymond
Nancie
N
Biologie Fonctionnelle, Insectes et Interactions (BF2I), UMR INRA/INSA de Lyon, 69621 Villeurbanne, France. nancie.reymond@jouy.inra.fr
Charles
Hubert
H
Duret
Laurent
L
Calevro
Federica
F
Beslon
Guillaume
G
Fayard
Jean-Michel
JM
D000465:Algorithms; D017076:Computer-Aided Design; D004867:Equipment Design / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods*; D015345:Oligonucleotide Probes / Q000138:chemical synthesis / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D011786:Quality Control; D012984:Software
D015345:Oligonucleotide Probes; D009841:Oligonucleotides