Ionic liquid-based liquid-phase microextraction, a new sample enrichment procedure for liquid chromatography.
Room temperature ionic liquids (RTILs) were used as extraction solvent in liquid-phase microextraction (LPME) coupled with liquid chromatography. Using 1-hexyl-3-methylimidazolium hexafluorophosphate ([C6MIM][PF6]) as extraction solvent, some parameters related to LPME of 4-nonylphenol (4-NP) and 4-tert-octylphenol (4-t-OP) were optimized. Although [C6MIM][PF6] can suspend a much larger volume of drop on the needle of the microsyringe than the conventional solvents such as 1-octanol and carbon tetrachloride, the method sensitivity was analyte dependent because of the different partition coefficients and the relatively large viscosity of [C6MIM][PF6]. The proposed procedure has a detection limit and enrichment factor of 0.3 microg l(-1) and 163 for 4-NP, and 0.7 microg l(-1) and 130 for 4-t-OP, respectively. Aqueous samples including tap water, river water, and effluent from sewage treatment plant were analyzed by the proposed method and the recoveries at 10 microg l(-1) spiked level were in the range of 90-113%.
Liu
Jing-fu
JF
Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, PO Box 2871, Beijing 100085, China.
Chi
Yu-guang
YG
Jiang
Gui-bin
GB
Tai
Chao
C
Peng
Jin-feng
JF
Hu
Jing-Tian
JT
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007477:Ions / Q000737:chemistry; D007525:Isoelectric Focusing; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012997:Solvents / Q000737:chemistry; D013048:Specimen Handling; D013997:Time Factors; D014867:Water / Q000737:chemistry
D007477:Ions; D012997:Solvents; D014867:Water