title: Cocaine dependence severity predicts outcome in outpatient detoxification from cocaine and alcohol.
abstract: This study compared the effects of alcohol and cocaine dependence severity on the outcome of outpatient detoxification from alcohol and cocaine. Subjects included 84 subjects with both alcohol and cocaine dependence admitted for outpatient detoxification. Fifty-three of the 84 subjects (63%) completed detoxification. Baseline cocaine use, cocaine craving, and cocaine withdrawal symptoms predicted detoxification outcome, whereas alcohol use, alcohol craving, and alcohol withdrawal symptoms did not. Among cocaine- and alcohol-dependent subjects, cocaine dependence severity appears to be a more important predictor of detoxification success than alcohol dependence severity.
authors.affiliation: Department of Psychiatry, University of Pennsylvania School of Medicine, Treatment Research Center, 3900 Chestnut Street, Philadelphia, PA 19104, USA. kampman_k@mail.trc.upenn.edu
authors.forename: Kyle M
authors.initials: KM
authors.lastname: Kampman
authors.forename: Helen M
authors.initials: HM
authors.lastname: Pettinati
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Volpicelli
authors.forename: David M
authors.initials: DM
authors.lastname: Oslin
authors.forename: Craig
authors.initials: C
authors.lastname: Lipkin
authors.forename: Thorne
authors.initials: T
authors.lastname: Sparkman
authors.forename: Charles P
authors.initials: CP
authors.lastname: O'Brien
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000628:therapy*; D019970:Cocaine-Related Disorders / Q000145:classification* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012720:Severity of Illness Index; D016896:Treatment Outcome