Temporo-occipital spikes: a typical EEG finding in Kabuki syndrome.
Kabuki syndrome is a rare dysmorphogenic disorder. The central nervous system is often involved, and epilepsy is a common symptom. The diagnosis is clinical, and no typical electroencephalographic findings have thus far been reported. We have documented temporo-occipital spikes in sleep electroencephalogram in all our three Kabuki patients. The location of the spikes was similar in all cases although their occurrence varied from continuous spiking to single spikes. We suggest that temporo-occipital spikes are typical in Kabuki syndrome and discuss the possible cause of this finding.
Oksanen
Virpi E
VE
Kanta-Häme Central Hospital, Hämeenlinna, Finland.
Arvio
Maria A
MA
Peippo
Maarit M
MM
Valanne
Leena K
LK
Sainio
Kimmo O
KO
D000015:Abnormalities, Multiple / Q000503:physiopathology*; D000293:Adolescent; D002648:Child; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000503:physiopathology*; D008297:Male; D009778:Occipital Lobe / Q000503:physiopathology*; D013577:Syndrome; D013702:Temporal Lobe / Q000503:physiopathology*