title: Effects of sevoflurane versus TIVA on gastric intramucosal pH and hemodynamic status in colon cancer surgery.
abstract: BACKGROUND
  Gastric tonometry is a minimally invasive device by which the adequacy of splanchnic blood flow is assessed indirectly. Patients undergoing major abdominal surgery are under the risk of developing splanchnic ischemia. The aim of this study was to compare gastric intramucosal pH and hemodynamic effects between sevoflurane and TIVA achieved by propofol.
  
  
  METHODS
  Forty patients of ASA I-II were studied. Twenty patients received sevoflurane (Group S) and 20 patients received TIVA by propofol (Group P). Continuous measurements were made at four intervals: (a) 30 minutes before the starting of the surgery, (b) at the first hour of the surgery, (c) at the second hour of the surgery, (d) at the first hour after ending of the surgery. The mean arterial pressure, heart rate, SpO2, EtCO2, body temperature, central venous pressure, urine output, intramucosal and arterial pH were monitored.
  
  
  RESULTS
  There were no significant differences between two groups regarding the studied parameters.
  
  
  CONCLUSIONS
  Sevoflurane and propofol did not cause any significant difference in hemodynamic effects and splanchnic circulation measured by gastric tonometry in ASA I-II patients operated on for colon cancer.
authors.affiliation: University of Istanbul, Cerrahpasa Medical Faculty, Department of Anesthesia, Istanbul, Turkey. zsalihoglu@yahoo.com
authors.forename: Ziya
authors.initials: Z
authors.lastname: Salihoğlu
authors.forename: Sener
authors.initials: S
authors.lastname: Demiroluk
authors.forename: Emre
authors.initials: E
authors.lastname: Görgün
authors.forename: Saffet
authors.initials: S
authors.lastname: Karaca
authors.forename: Faik
authors.initials: F
authors.lastname: Ozçelik
mesh_terms: D000704:Analysis of Variance; D000771:Anesthesia, Intravenous / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000494:pharmacology; D018686:Anesthetics, Intravenous / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects* / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry; D008738:Methyl Ethers / Q000494:pharmacology*; D008875:Middle Aged; D009949:Orientation / Q000187:drug effects; D015742:Propofol / Q000494:pharmacology; D000077149:Sevoflurane; D013067:Speech Perception / Q000187:drug effects; D014556:Urine
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D000077149:Sevoflurane; D015742:Propofol