Comparison of Campylobacter jejuni isolates implicated in Guillain-Barré syndrome and strains that cause enteritis by a DNA microarray.
We asked whether Campylobacter jejuni isolated from patients with Guillain-Barré syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.
Leonard
Edward E
EE
Department of Microbiology and Immunology, Stanford University, Stanford, California 94305, USA.
Tompkins
Lucy S
LS
Falkow
Stanley
S
Nachamkin
Irving
I
D016123:Campylobacter jejuni / Q000235:genetics*; D004751:Enteritis / Q000382:microbiology*; D014644:Genetic Variation; D016680:Genome, Bacterial; D020275:Guillain-Barre Syndrome / Q000382:microbiology*; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*