[Effects of enriched oxygen on human free radical metabolism during exercise at 5 380 m plateau].
OBJECTIVE
To study the effect of enriched oxygen on free radical metabolism at high altitude.


METHODS
SOD, GSH-Px and MDA were measured in 10 health young men after step in a room with or without oxygen enrichment at high altitude of 5 380 m.


RESULTS
After exercise in the oxygen-enriched room, SOD and GSH-Px increased significantly while MDA decreased notably (P<0.01) than those after exercise in the room without oxygen enrichment (P<0.05 or P<0.01).


CONCLUSIONS
Enriched oxygen can decrease damage from free radical at high altitude.
Cui
Jian-hua
JH
The 18th Hospital, PLA, Yechen, China.
Zhang
Xi-zhou
XZ
Zhang
Jian-lin
JL
Zhang
Fang
F
Ma
Yong
Y
Wang
Da-wen
DW
D000328:Adult; D000531:Altitude; D015444:Exercise / Q000502:physiology*; D005609:Free Radicals / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010100:Oxygen / Q000494:pharmacology*; D010102:Oxygen Inhalation Therapy; D013482:Superoxide Dismutase / Q000187:drug effects / Q000378:metabolism
D005609:Free Radicals; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D010100:Oxygen