Components of early maternal environment affecting the predisposition to catalepsy.
Reciprocal pup substitution (cross-fostering) in cataleptic GC (designated so by the initials of words "genetic" and "catalepsy") and control Wistar females resulted in attenuation of cataleptic predisposition in GC rats fostered by Wistar foster-mothers. The latter demonstrate a more intense maternal care than GC females. There was a significant negative correlation between the frequency of mother staying in nest and the duration of pinch-induced catalepsy in pups fostered by her. In the home-cage retrieval test, the females of the strains compared showed a significant dependence of the latencies of approach to, and retrieval of, pups on their own and the pups' genotype.
Petrenko
O I
OI
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Chuguy
V F
VF
Barykina
N N
NN
Alekhina
T A
TA
Kolpakov
V G
VG
Amstislavsky
S Ya
SY
D000367:Age Factors; D000818:Animals; D002375:Catalepsy / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D008425:Maternal Behavior; D051381:Rats; D017208:Rats, Wistar; D012931:Social Environment