title: Hepatosplenic gammadelta T-cell lymphoma in a 10-year-old boy successfully treated with hematopoietic stem cell transplantation.
abstract: The authors report a 10-year-old boy with hepatosplenic gammadelta T-cell lymphoma, a rare form of lymphoma that is highly aggressive, exceedingly rare in children, and primarily seen in young men. Conventional multi-agent chemotherapy appears to be inadequate for cure. This is the first report with this type of lymphoma in a boy less than 15 years old treated with hematopoietic stem cell transplantation (HSCT).
authors.affiliation: Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada. adam.gassas@sickkids.ca
authors.forename: Adam
authors.initials: A
authors.lastname: Gassas
authors.forename: Melanie
authors.initials: M
authors.lastname: Kirby
authors.forename: Sheila
authors.initials: S
authors.lastname: Weitzman
authors.forename: Bo
authors.initials: B
authors.lastname: Ngan
authors.forename: Oussama
authors.initials: O
authors.lastname: Abla
authors.forename: John J
authors.initials: JJ
authors.lastname: Doyle
mesh_terms: D002648:Child; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology*; D016399:Lymphoma, T-Cell / Q000276:immunology* / Q000628:therapy; D008297:Male; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis*; D013160:Splenic Neoplasms / Q000276:immunology*; D033581:Stem Cell Transplantation; D016896:Treatment Outcome
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta