title: A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective.
abstract: Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.
authors.affiliation: Max-Planck-Institute for Developmental Biology, 72076 Tübingen, Germany.
authors.forename: Snjezana
authors.initials: S
authors.lastname: Rendulic
authors.forename: Pratik
authors.initials: P
authors.lastname: Jagtap
authors.forename: Andrea
authors.initials: A
authors.lastname: Rosinus
authors.forename: Mark
authors.initials: M
authors.lastname: Eppinger
authors.forename: Claudia
authors.initials: C
authors.lastname: Baar
authors.forename: Christa
authors.initials: C
authors.lastname: Lanz
authors.forename: Heike
authors.initials: H
authors.lastname: Keller
authors.forename: Carey
authors.initials: C
authors.lastname: Lambert
authors.forename: Katy J
authors.initials: KJ
authors.lastname: Evans
authors.forename: Alexander
authors.initials: A
authors.lastname: Goesmann
authors.forename: Folker
authors.initials: F
authors.lastname: Meyer
authors.forename: R Elizabeth
authors.initials: RE
authors.lastname: Sockett
authors.forename: Stephan C
authors.initials: SC
authors.lastname: Schuster
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D001422:Bacterial Adhesion / Q000235:genetics; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism; D001501:Bdellovibrio / Q000166:cytology / Q000235:genetics* / Q000254:growth & development* / Q000502:physiology; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D019295:Computational Biology; D003600:Cytosol / Q000378:metabolism; D010861:Fimbriae, Bacterial / Q000235:genetics / Q000502:physiology; D005407:Flagella / Q000235:genetics / Q000502:physiology; D022761:Gene Transfer, Horizontal; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D023281:Genomics; D006090:Gram-Negative Bacteria; D006867:Hydrolases / Q000235:genetics / Q000378:metabolism; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism; D016366:Open Reading Frames; D010457:Peptidoglycan / Q000378:metabolism; D017422:Sequence Analysis, DNA
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D026901:Membrane Transport Proteins; D010457:Peptidoglycan; D000255:Adenosine Triphosphate; D006867:Hydrolases