title: Outcome of patients with cardiac diseases admitted to coronary care units: a report from Lazio, Italy.
abstract: BACKGROUND
  Coronary care units (CCUs) currently treat a variety of diseases, but little is known about the effectiveness of CCUs on heart conditions other than acute myocardial infarction.
  
  
  OBJECTIVE
  The objectives of this study were to evaluate the association between direct admission to CCUs and the risk of inhospital death in patients with heart disease, to investigate factors affecting direct admission to a CCU, and to assess the effect of CCU admission on the use of invasive procedures in patients with arrhythmias.
  
  
  METHODS
  We conducted a retrospective analysis of discharge-abstract data from Lazio, Italy, hospitals. We used logistic regression, propensity score, and instrumental variable analysis to compare inhospital risk of death between patients admitted to CCUs and to ordinary wards in 13 different groups of heart disease. We used linear regression to study the association between the rate of CCU admission and the relative risk of death.
  
  
  RESULTS
  The study included 181,049 heart disease admissions, of which 8620 were admitted to CCUs (4.8%). Risk of death was significantly lower in patients admitted directly to CCUs for "acute myocardial infarction" (odds ratio [OR], 0.57), "acute ischemic heart disease" (OR, 0.55), and "other arrhythmias" (OR, 0.56). Mortality ORs were inversely related to the rate of CCU admission. CCU patients with arrhythmias received more invasive procedures (OR, 2.70) than non-CCU patients.
  
  
  CONCLUSIONS
  Direct admission to a CCU is associated with a decrease in mortality for patients with "acute myocardial infarction," "acute heart ischemia," and "other arrhythmias." Patients most likely to benefit from CCU care are preferentially admitted to CCUs. CCUs make larger use of invasive procedures than ordinary wards.
authors.affiliation: Department of Epidemiology, Local Health Authority RME, Roma, Italy. primcare@asplazio.it
authors.forename: Carlo
authors.initials: C
authors.lastname: Saitto
authors.forename: Carla
authors.initials: C
authors.lastname: Ancona
authors.forename: Danilo
authors.initials: D
authors.lastname: Fusco
authors.forename: Massimo
authors.initials: M
authors.lastname: Arcà
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Perucci
mesh_terms: D000368:Aged; D003325:Coronary Care Units / Q000592:standards / Q000706:statistics & numerical data*; D005260:Female; D019538:Health Care Surveys; D006331:Heart Diseases / Q000401:mortality / Q000628:therapy*; D006742:Hospital Bed Capacity / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D016017:Odds Ratio; D010043:Outcome and Process Assessment, Health Care; D010343:Patient Admission / Q000706:statistics & numerical data; D012044:Regression Analysis