Neuroimaging in autistic spectrum disorder (ASD).
Autistic spectrum disorder (ASD) is a lifelong developmental disorder characterized by impairment in socialization and communication. Neuroimaging research has shown abnormalities in the frontal lobes, limbic systems, and cerebella of individuals with ASD. Recently, abnormal developmental trajectories of brain growth have been reported, with increases in brain volume (in both gray and white matter) seen in younger rather than older individuals with this disorder. Despite 30 years of research, a reliable marker for ASD has not been identified. Therefore, routine neuroimaging for individuals with ASD is not recommended.
Sokol
Deborah K
DK
Department of Neurology, Indiana University School of Medicine, 702 Barnhill Drive, R1 1757, Indianapolis, IN 46202, USA. dksokol@iupui.edu
Edwards-Brown
Mary
M
D001321:Autistic Disorder / Q000000981:diagnostic imaging / Q000473:pathology*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon