The true ligand of the NOD2 receptor is peptidoglycan instead of lipopolysaccharide: a schematic representation of ligand-receptor interactions and NF-kappa B activation.
Morré
Servaas A
SA
Ouburg
Sander
S
Klinkenberg-Knol
Elly C
EC
Mulder
Chris J
CJ
Peña
A Salvador
AS
D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D008024:Ligands; D008070:Lipopolysaccharides; D016328:NF-kappa B / Q000378:metabolism*; D053473:Nod2 Signaling Adaptor Protein; D010457:Peptidoglycan / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*
D047908:Intracellular Signaling Peptides and Proteins; D008024:Ligands; D008070:Lipopolysaccharides; D016328:NF-kappa B; C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein; D010457:Peptidoglycan; D011956:Receptors, Cell Surface