title: Gonadotropin releasing hormone antagonists and cryopreservation outcome: a review.
abstract: METHODS
  The outcome of freeze-thaw cycles with pronuclear stage oocytes or embryos, derived from collecting cycles stimulated with gonadotropin-releasing hormone (GnRH)-antagonists' protocols, was reviewed.
  
  
  CONCLUSIONS
  The viability of cryopreserved pronuclear stage oocytes and embryos, the quality of transferred embryos and the pregnancy rates of the freeze-thaw cycles seem to be satisfactory regardless of the type and dose of GnRH-antagonist.
authors.affiliation: Laboratory of Reproductive Physiology-IVF, Faculty of Medicine, Democritus University of Thrace, 68100, Dragana, Alexandroupolis, Greece. nnikolettos@hotmail.com
authors.forename: N
authors.initials: N
authors.lastname: Nikolettos
authors.forename: B
authors.initials: B
authors.lastname: Asimakopoulos
authors.forename: M
authors.initials: M
authors.lastname: Simopoulou
authors.forename: S
authors.initials: S
authors.lastname: Al-Hasani
authors.forename: K
authors.initials: K
authors.lastname: Diedrich
mesh_terms: D015925:Cryopreservation; D010064:Embryo Implantation / Q000187:drug effects; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000494:pharmacology; D006727:Hormone Antagonists / Q000494:pharmacology*; D006801:Humans; D008186:Luteolytic Agents / Q000494:pharmacology; D009865:Oocytes / Q000187:drug effects / Q000502:physiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D011966:Receptors, LHRH / Q000378:metabolism; D017329:Triptorelin Pamoate / Q000494:pharmacology
chemical_list: D006727:Hormone Antagonists; D008186:Luteolytic Agents; D011966:Receptors, LHRH; D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone; C061018:ganirelix; C062876:cetrorelix