Chemical analysis and antifungal activity of Thymus striatus.
The essential oil composition from Thymus striatus collected from Mountain Orjen (Montenegro) has been investigated by gas chromatography-mass spectrometry. Thymol, gamma-terpinene and p-cymene were found to be the major components. Furthermore, the oil and its major component, thymol, were analysed for potential antifungal activity against plant, animal and human pathogenic fungi from different genera by a macrodilution test. The oil exhibited a strong inhibitory effect against all fungi investigated.
Couladis
M
M
School of Pharmacy, Department of Pharmacognosy and Chemistry of Natural Products, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. kouladi@pharm.uoa.gr
Tzakou
O
O
Kujundzic
S
S
Sokovic
M
M
Mimica-Dukic
N
N
D000935:Antifungal Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D003904:Mitosporic Fungi / Q000187:drug effects*; D008517:Phytotherapy; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D013943:Thymol / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D046930:Thymus Plant / Q000737:chemistry*
D000935:Antifungal Agents; D010938:Plant Oils; D013943:Thymol