title: [Immediate type food hypersensitivity associated with atopic dermatitis in children].
abstract: Food allergy is frequently associated with atopic dermatitis (AD) in children. Appropriate elimination diet is necessary in the case of immediate food hypersensitivity, regardless it causes worsening of the chronic eczema or not. Here we report the prevalence of immediate type food allergy diagnosed by oral food challenge or the episodes of apparent acute allergic reaction in the AD patients (n=182, average age 4.9+/-5.1), who visited our clinic within one year. The prevalence of food allergy in the AD patients was 85.7% in age 0 years, 75.6% in age 1,65.4% in age 2, and declined to 13.9% in age 7 years old or more. The offending foods were egg, milk, wheat, fish and so on. The symptoms of food allergy included skin, gastrointestinal or respiratory manifestations, and also anaphylaxis. In conclusion, immediate type food allergy is frequently associated with childhood AD, and appropriate elimination of the offending food is necessary to avoid the acute allergic reaction including anaphylaxis.
authors.affiliation: Division of Allergology, Aichi Children's Health and Medical Center, Japan. koumei_itoh@mx.achmc.pref.aichi.jp
authors.forename: Komei
authors.initials: K
authors.lastname: Ito
authors.forename: Masashi
authors.initials: M
authors.lastname: Morishita
authors.forename: Akemi
authors.initials: A
authors.lastname: Ito
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Shinpei
authors.initials: S
authors.lastname: Torii
mesh_terms: D000375:Aging / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000150:complications / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood; D007223:Infant; D008297:Male
chemical_list: D007073:Immunoglobulin E