Practical synthesis of new and highly efficient ligands for the Suzuki reaction of aryl chlorides.
A practical synthesis of a novel class of phosphine ligands, phosphino substituted N-aryl pyrroles (PAP ligands), has been developed. These ligands are applied in the palladium-catalyzed coupling of a variety of aryl and heteroaryl chlorides with phenylboronic acid showing exceedingly high turnover numbers at mild reaction temperatures and even at room temperature.
Zapf
Alexander
A
Leibniz-Institut für Organische Katalyse an der Universität Rostock e.V., Buchbinderstr. 5-6, 18055 Rostock, Germany.
Jackstell
Ralf
R
Rataboul
Franck
F
Riermeier
Thomas
T
Monsees
Axel
A
Fuhrmann
Christa
C
Shaikh
Nadim
N
Dingerdissen
Uwe
U
Beller
Matthias
M