Enteropathogenic activity and invasion of HEp-2 cells by Aeromonas caviae clinical isolates.
Twenty Aeromons caviae isolates from stool of children with diarrhea symptoms were examined for virulence-associated properties: production of cytotoxic and cytotonic toxins, and invasive ability. Most of A. caviae strains were cytotoxic to Vero and CHO cells and produced cytotonic toxins which caused elongation of CHO cells. Moreover, five of A. caviae strains revealed invasive ability towards HEp-2 cells.
Krzymińska
Sylwia
S
Department of Microbiology, A. Mickiewicz University Fredry 10, 61-701 Poznań, Poland.
Kaznowski
Adam
A
Lindner
Karolina
K
Mnichowska
Magdalena
M
D000333:Aeromonas / Q000302:isolation & purification / Q000378:metabolism / Q000472:pathogenicity*; D000818:Animals; D001422:Bacterial Adhesion / Q000502:physiology; D001426:Bacterial Proteins; D016466:CHO Cells; D002648:Child; D002522:Chlorocebus aethiops; D006224:Cricetinae; D003967:Diarrhea / Q000382:microbiology; D004768:Enterotoxins / Q000096:biosynthesis; D004847:Epithelial Cells; D005243:Feces / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D014709:Vero Cells
D001426:Bacterial Proteins; D004768:Enterotoxins; C082174:cytolytic enterotoxin protein, Aeromonas