title: [Primary urothelial carcinoma of the bulbomembranous urethra. Histologic and immunohistochemical study of a case].
abstract: OBJECTIVE
  We report a case of a primary urothelial carcinoma of the bulbomembranous urethra, with special emphasis on histopathological and immunohistochemical findings.
  
  
  RESULTS
  A 63-year-old man presented urethral obstruction symptoms. A radical phalectomy was performed and a 4.5 x 4 cm bulbomembranous urethral tumor was observed. Histopathological analysis disclosed an urothelial carcinoma, that showed positive immunostaining for cytokeratin AE1/AE3, cytokeratin 7, carcinoembrionic antigen and epithelial membrane antigen. The patient received radiotherapy and adjuvant chemotherapy and is currently free of disease.
  
  
  CONCLUSIONS
  Posterior male urothelial carcinoma of the urethra is a rare neoplasm that usually is mistaken clinically for a benign lesion. The diagnostic is generally made in advanced stages with a poor therapeutical response.
authors.affiliation: Servicio de Anatomía Patológica, Hospital Vargas de Caracas, Caracas, Venezuela. parada@cantv.net
authors.forename: David
authors.initials: D
authors.lastname: Parada
authors.forename: Alberto
authors.initials: A
authors.lastname: Páez
authors.forename: Marisela
authors.initials: M
authors.lastname: Acosta
authors.forename: Luis
authors.initials: L
authors.lastname: Caricote
authors.forename: Eduardo
authors.initials: E
authors.lastname: Trujillo
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Luigi
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Farías
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014523:Urethral Neoplasms / Q000473:pathology*