title: [Synthesis and antiviral activity of ureides and carbamates of betulinic acid and its derivatives].
abstract: Ureides and carbamates of betulinic acid and its derivatives were prepared in good yields by interaction of betulinic acid, betulonic acid, and betulonic acid 3-oxime with amines, amino acids, and alcohols. Ureides of betulonic acid containing L-Val and L-Met residues were found to be effective against herpes simplex type 1 virus. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2003, vol. 29, no. 6; see also http://www.maik.ru.
authors.affiliation: Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054 Russia. obf@anrb.ru
authors.forename: O B
authors.initials: OB
authors.lastname: Flekhter
authors.forename: E I
authors.initials: EI
authors.lastname: Boreko
authors.forename: L R
authors.initials: LR
authors.lastname: Nigmatullina
authors.forename: E V
authors.initials: EV
authors.lastname: Tret'iakova
authors.forename: N I
authors.initials: NI
authors.lastname: Pavlova
authors.forename: L A
authors.initials: LA
authors.lastname: Baltina
authors.forename: S N
authors.initials: SN
authors.lastname: Nikolaeva
authors.forename: O V
authors.initials: OV
authors.lastname: Savinova
authors.forename: F Z
authors.initials: FZ
authors.lastname: Galin
authors.forename: G A
authors.initials: GA
authors.lastname: Tolstikov
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D002219:Carbamates / Q000138:chemical synthesis / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D053978:Pentacyclic Triterpenes; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000138:chemical synthesis* / Q000494:pharmacology*; D000094062:Betulinic Acid
chemical_list: D000998:Antiviral Agents; D002219:Carbamates; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; D000094062:Betulinic Acid