title: Major complications of urinary diversion after pelvic exenteration for gynecologic malignancies: a 23-year mono-institutional experience in 124 patients.
abstract: OBJECTIVE
  The objective of this study was to analyze the postoperative outcome of patients undergoing urinary diversion at the time of pelvic exenteration.
  
  
  METHODS
  Between January 1980 and December 2002, 232 pelvic exenterations for gynecologic malignancies were performed in our hospital. One hundred and twenty-four included a urinary diversion. There were locally advanced or recurrent cancers including 101 cervical, 11 endometrial, 5 vagina, 2 ovarian malignancies and 5 pelvic sarcoma.
  
  
  RESULTS
  Ninety patients (72.5%) had a history of previous irradiation. Exenterations were 69 anterior and 55 total. Urinary diversion included 14 bilateral ureterostomies, 62 trans-intestinal diversion and 48 continent diversion using distal ileum and right colon. Pelvic filling was performed in 56 patients (45%). Low colorectal anastomosis was performed in 42 of 48 supralevator pelvic exenteration (87.5%). Postoperative mortality rate was 8% (10/124). Overall 12-week postoperative morbidity rate was 52% (65/124) and appears to be significantly higher in irradiated patients and after total exenteration. In trans-intestinal noncontinent group, eight patients were reoperated for a complication directly related to urinary diversion procedure. No reoperation for such a complication was performed in the continent urinary diversion group.
  
  
  CONCLUSIONS
  Ileocolic continent pouch seems to be the safer urinary diversion procedure after exenteration for gynecological malignancies especially in irradiated patients and after total exenteration.
authors.affiliation: Department of Surgery, Institut Paoli-Calmettes, 13009 Marseille, France.
authors.forename: G
authors.initials: G
authors.lastname: Houvenaeghel
authors.forename: V
authors.initials: V
authors.lastname: Moutardier
authors.forename: G
authors.initials: G
authors.lastname: Karsenty
authors.forename: F
authors.initials: F
authors.lastname: Bladou
authors.forename: B
authors.initials: B
authors.lastname: Lelong
authors.forename: M
authors.initials: M
authors.lastname: Buttarelli
authors.forename: J R
authors.initials: JR
authors.lastname: Delpero
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005833:Genital Neoplasms, Female / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D010385:Pelvic Exenteration / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014547:Urinary Diversion / Q000009:adverse effects*