title: Laser in situ keratomileusis improves visual acuity in some adult eyes with amblyopia.
abstract: OBJECTIVE
  To report the results of laser in situ keratomileusis (LASIK) in a series of adult patients with amblyopia.
  
  
  METHODS
  A retrospective noncomparative review was performed on patients with amblyopia who underwent LASIK for correction of ametropia, using the Summit Krumeich Barraquer microkeratome and the Nidek EC-5000 excimer laser. Data were collected on uncorrected visual acuity, best spectacle-corrected visual acuity, manifest refraction, anterior segment evaluation, intraocular pressure, corneal topography, and dilated fundus examination (preoperative and postoperatively on day 1, months 2 and 6).
  
  
  RESULTS
  Eight eyes of seven patients were included, with a mean patient age of 30 +/- 10 years (range 21 to 49 yr). Mean preoperative spherical equivalent refraction was -4.70 D (range -12.62 to +4.71 D) and the best spectacle-corrected visual acuity varied from 20/32 to 20/80. At 2 months after LASIK, mean spherical equivalent refraction was -0.37 +/- 0.60 D (range -1.37 to + 0.60 D), uncorrected visual acuity ranged between 20/20 to 20/30, and a mean gain of 3 Snellen lines (range 2 to 4 lines) was observed. All patients reported significant subjective improvement in their perception of vision. The visual acuity and subjective improvement were maintained throughout 6 months postoperatively.
  
  
  CONCLUSIONS
  LASIK with the Nidek EC-5000 laser for correction of ametropia in adult amblyopic eyes provided encouraging results for visual acuity improvement beyond correction of the refractive error.
authors.affiliation: The Refractive Surgery Center, Herzliya, Israel. barequet@cs.technion.ac.il
authors.forename: Irina S
authors.initials: IS
authors.lastname: Barequet
authors.forename: Tamara
authors.initials: T
authors.lastname: Wygnanski-Jaffe
authors.forename: Ami
authors.initials: A
authors.lastname: Hirsh
mesh_terms: D000328:Adult; D000550:Amblyopia / Q000150:complications / Q000503:physiopathology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012030:Refractive Errors / Q000150:complications / Q000503:physiopathology; D054140:Refractive Surgical Procedures; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*