title: Infracyanine-assisted internal limiting membrane peeling in macular hole repair: does it make a difference?
abstract: OBJECTIVE
  To investigate whether Infracyanine-assisted internal limiting membrane (ILM) peeling in macular hole repair affects the anatomical and functional outcome and complication rate.
  
  
  METHODS
  A retrospective analysis of 139 consecutive cases of stage 2 and stage 3 macular hole repairs with or without Infracyanine-assisted ILM peeling.
  
  
  RESULTS
  There were 67 eyes with Infracyanine staining of the ILM and 72 eyes in the non-ILM-stained group. The results are analyzed functionally, anatomically and in terms of complications. A similar anatomical and functional closure rate was obtained with one unclosed macular hole in the stained group and two in the non-stained group (P=1.0). Fifty-two percent of the eyes in the stained group and 59% of those in the non-stained group achieved 0.5 vision or better (P=0.40). The mean postoperative vision was 0.55 in the stained group and 0.54 in the non-stained group (P=0.65). The mean improvement in vision was 0.40 in the stained group and 0.36 in the non-stained group (P=0.21).
  
  
  CONCLUSIONS
  Anatomical and functional results are similar with or without Infracyanine-assisted ILM peeling. There was no apparent adverse effect of Infracyanine use on visual function, and no apparent retinal toxicity was found.
authors.affiliation: Vitreoretinal Unit, Frere Hospital, 18 St James Road, 5201 East London, South Africa. eyecare@iafrica.com
authors.forename: Kelvin
authors.initials: K
authors.lastname: Rivett
authors.forename: Louis
authors.initials: L
authors.lastname: Kruger
authors.forename: Sarah
authors.initials: S
authors.lastname: Radloff
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001485:Basement Membrane / Q000473:pathology / Q000601:surgery; D004396:Coloring Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D007208:Indocyanine Green / Q000009:adverse effects / Q000031:analogs & derivatives*; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000175:diagnosis / Q000601:surgery*; D012189:Retrospective Studies; D013194:Staining and Labeling / Q000379:methods; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D004396:Coloring Agents; C116320:Infracyanine green; D007208:Indocyanine Green