title: Depression score predicts weight loss following Roux-en-Y gastric bypass.
abstract: BACKGROUND
  The prevalence of obesity is increasing in the United States. Bariatric surgery is the only intervention that can reliably induce and maintain significant weight loss in obese patients. The association between pre-surgical severity of depression and success at weight loss following Roux-en-Y gastric bypass (RYGBP) has not yet been fully elucidated.
  
  
  METHODS
  145 charts of patients who underwent RYGBP for morbid obesity were reviewed. 47 patients who filled out the Beck Depression Inventory (BDI) before surgery and completed 1 year of follow-up were studied. The relationship between pre-surgical severity of depression and success at weight loss was examined through multivariate regression analysis using percent excess weight loss (%EWL) as a dependent variable and BDI score as one of the predictors.
  
  
  RESULTS
  Weight loss at 1 year was significantly related to the BDI score before surgery (P =0.014). BDI score was also found to be a significant predictor of the amount of weight lost (kg) 1 year after surgery (P =0.027). Age (P =0.03) and initial body mass index (BMI) (P =0.011) were the only other variables with significant independent relations to %EWL.
  
  
  CONCLUSIONS
  Our data show a positive correlation between pre-surgical severity of depression as measured by BDI score and the 1-year success at weight loss after RYGBP as measured by %EWL. More depressed individuals tend to lose greater amounts of weight compared with less depressed individuals. Future prospective studies should examine possible mechanisms and effects of depression and other psychiatric disturbances on long-term weight loss after RYGBP.
authors.affiliation: Department of Medicine, St.Luke's-Roosevelt Hospital, New York, USA.
authors.forename: Yelena
authors.initials: Y
authors.lastname: Averbukh
authors.forename: Stanley
authors.initials: S
authors.lastname: Heshka
authors.forename: Hazem
authors.initials: H
authors.lastname: El-Shoreya
authors.forename: Louis
authors.initials: L
authors.lastname: Flancbaum
authors.forename: Allan
authors.initials: A
authors.lastname: Geliebter
authors.forename: Sherif
authors.initials: S
authors.lastname: Kamel
authors.forename: F Xavier
authors.initials: FX
authors.lastname: Pi-Sunyer
authors.forename: Blandine
authors.initials: B
authors.lastname: Laferrère
mesh_terms: D000328:Adult; D000713:Anastomosis, Roux-en-Y; D015897:Comorbidity; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology* / Q000523:psychology / Q000601:surgery*; D011581:Psychological Tests; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology*