title: A novel chiral terpyridine macrocycle as a fluorescent sensor for enantioselective recognition of amino acid derivatives.
abstract: Terpyridine macrocycle 1 is shown to be a strong chelating agent for organic ammonium salts and also a useful chromophore in fluorescent sensing. It exhibits very good enantioselectivity (K(obs)(S)/K(obs)(R)= 3.8) in chiral discrimination of alpha-phenylglycine methyl ester hydrochloride (PhEtOMe).
authors.affiliation: Department of Biology and Chemistry, Open Laboratory of Chirotechnology, Institute of Molecular Technology for Drugs Discovery and Synthesis, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong SAR, China.
authors.forename: Wing-Leung
authors.initials: WL
authors.lastname: Wong
authors.forename: Ka-Hung
authors.initials: KH
authors.lastname: Huang
authors.forename: Pang-Fei
authors.initials: PF
authors.lastname: Teng
authors.forename: Chi-Sing
authors.initials: CS
authors.lastname: Lee
authors.forename: Hoi-Lun
authors.initials: HL
authors.lastname: Kwong
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D005456:Fluorescent Dyes; D047028:Macrocyclic Compounds; D011725:Pyridines