Positron emission tomography in pediatric radiation oncology: integration in the treatment-planning process.
The application of PET imaging to pediatric radiation oncology allows new approaches to targeting and selection of radiation dose based not only on the size of a tumor, but also on its metabolic activity. In order to integrate PET into treatment planning for radiation oncology, logistical issues regarding patient setup, image fusion, and target selection must be addressed. Through prospective study, the role of PET in pediatric malignancies will be established for diagnosis, treatment, and surveillance. To explore the potential role of PET and its incorporation into treatment planning in pediatric radiation oncology, an example case of pediatric Hodgkin's disease is discussed.
Krasin
Matthew J
MJ
Department of Radiological Sciences, Division of Radiation Oncology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA. matthew.krasin@stjude.org
Hudson
Melissa M
MM
Kaste
Sue C
SC
D000293:Adolescent; D002648:Child; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000532:radiotherapy; D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D010346:Patient Care Management; D018787:Radiation Oncology; D018714:Radiotherapy, Adjuvant / Q000379:methods; D014055:Tomography, Emission-Computed / Q000379:methods*