Antioxidants and atherosclerosis.
The oxidative modification of low-density lipoprotein (LDL) can be induced by various active species by different mechanisms. Vitamin E and other radical-scavenging antioxidants can inhibit the free radical-mediated oxidation of LDL, but they are not effective against LDL oxidation induced by non-radical mechanisms.
Niki
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National Institute of Advanced Industrial Science and Technology, Human Stress Signal Research Center, 1-8-31 Midorigaoka, Ikeda 563-8577, Japan. etsuo-niki@aist.go.jp
D000818:Animals; D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology; D001161:Arteriosclerosis / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism; D016877:Oxidants / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects
D000975:Antioxidants; D008077:Lipoproteins, LDL; D016877:Oxidants