title: [Misuse of tianeptine: five cases of abuse].
abstract: Five cases of excessive consumption of tianeptine suggest possible drug-abuse of this substance. This side effect is unknown in animals and humans. According to DSM IV, CIM 10 criteria and the French public health code, these five patients had pathological profiles of psychoactive drug abusers. Tianeptine dosage was always used higher than recommended and the drug was taken in association with other psychotropes. Withdrawal was difficult and induced anxiety and other disorders which led to relapse in most of the patients.
authors.affiliation: Service du Contrôle Médical, CPAM de Quimper, Cité du Guerlach, BP 1723, 29107 Quimper Cedex.
authors.forename: Loïc
authors.initials: L
authors.lastname: Leterme
authors.forename: Yves-Stéphane
authors.initials: YS
authors.lastname: Singlan
authors.forename: Valérie
authors.initials: V
authors.lastname: Auclair
authors.forename: Reynald
authors.initials: R
authors.lastname: Le Boisselier
authors.forename: Vincent
authors.initials: V
authors.lastname: Frimas
mesh_terms: D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D019966:Substance-Related Disorders / Q000175:diagnosis*; D013841:Thiazepines / Q000009:adverse effects*
chemical_list: D000929:Antidepressive Agents, Tricyclic; D013841:Thiazepines; C050504:tianeptine