Teratological studies of prenatal exposure of mice to a 20 kHz sawtooth magnetic field.
In order to evaluate the importance of gestational age in possible effects due to exposure to a 20 kHz sawtooth magnetic field, pregnant ICR mice at gestational 2.5-15.5 days post-coitus, which is the most sensitive stage for the induction of major congenital malformations, were exposed in a carrousel irradiator. The mice were exposed to a 20 kHz intermediate frequency (IF) sawtooth magnetic field had a 6.5 microT peak intensity for 8 h/day. The animals were sacrificed on the 18th day of gestation; and the fetuses were examined for mortality, growth retardation, changes in head size, and other morphological abnormalities. From the above conditions, it is concluded that the exposure to a 20 kHz sawtooth magnetic field with 6.5 microT peak intensity does not inflict any adverse effect on fetuses of pregnant mice.
Kim
Sung-Ho
SH
College of Veterinary Medicine, Chonnam National University, Kwangju, South Korea. yslee@kcch.re.kr
Song
Ji-Eun
JE
Kim
Se-ra
SR
Oh
Heon
H
Gimm
Youn-Myoung
YM
Yoo
Done-Sik
DS
Pack
Jeong-Ki
JK
Lee
Yun-Sil
YS
D000016:Abnormalities, Radiation-Induced / Q000209:etiology*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005317:Fetal Growth Retardation / Q000209:etiology*; D020567:Fetal Weight / Q000528:radiation effects*; D005333:Fetus / Q000528:radiation effects*; D051379:Mice; D008813:Mice, Inbred ICR; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011829:Radiation Dosage; D016019:Survival Analysis