title: In vitro bioactivity of laser ablation pseudowollastonite coating.
abstract: Pseudowollastonite (psW) coatings on titanium alloys substrates were prepared by laser ablation and immersed in simulated body fluid (SBF) for different periods in order to investigate the nucleation and growth of hydroxyapatite (HA)-like formation on their surface. The structure of the coatings before soaking was analysed by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The interfacial reactions product was examined by thin-film XRD, SEM and transmission electron microscopy at low and high resolution level, both fitted with energy-dispersive X-ray spectroscopy. Additional changes in ionic concentration, using inductively couple plasma atomic emission spectroscopy, were determined as well as pH right at the psW-coatings/SBF interface using an ion-sensitive field effect transistor. The solution composition changes, increasing the Ca(2+) and Si(4+) concentration and pH as a function of the soaking time while HPO(4)(2-) decreased. The results obtained showed that the coating surfaces were covered by HA-like, which indicated that the psW-coating possesses good bioactivity and also suggested that the mechanism of HA-like layer formation in SBF was similar to that showed in in vitro test by other silica-based materials.
authors.affiliation: Instituto de Bioingenieria, Universidad Miguel Hernandez, Edificio Torrevaillo Avda. Ferrocarril s/n, Elche, 03202 Alicante, Spain. peidad@umh.es
authors.forename: P N
authors.initials: PN
authors.lastname: De Aza
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández-Pradas
authors.forename: P
authors.initials: P
authors.lastname: Serra
mesh_terms: D000497:Alloys; D040761:Biomimetic Materials; D001826:Body Fluids / Q000737:chemistry*; D017610:Calcium Compounds / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D006358:Hot Temperature; D007834:Lasers; D008422:Materials Testing; D008968:Molecular Conformation; D010316:Particle Size; D017640:Silicates / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D000497:Alloys; D017610:Calcium Compounds; D020099:Coated Materials, Biocompatible; D017640:Silicates; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium; C031293:calcium silicate