title: The role of neurosurgery in the treatment of cerebral metastases from choriocarcinoma: a report of two cases.
abstract: Cerebral metastases from choriocarcinoma are a poor prognostic indicator of outcome in both the World Health Organization and FIGO classification systems. However, with the increased experience with chemotherapy and radiotherapy the prognosis of this group of patients has improved substantially. Neurosurgery remains an option for selected patients. We present two patients who underwent craniotomy as part of their management of choriocarcinoma, and review the role of neurosurgery in the treatment of gestational trophoblastic disease.
authors.affiliation: Department of Neurosurgery, Groote Schuur Hospital, University of Cape Town, South Africa.
authors.forename: P L
authors.initials: PL
authors.lastname: Semple
authors.forename: L
authors.initials: L
authors.lastname: Denny
authors.forename: M
authors.initials: M
authors.lastname: Coughlan
authors.forename: R
authors.initials: R
authors.lastname: Soeters
authors.forename: L
authors.initials: L
authors.lastname: Van Wijk
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D003399:Craniotomy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D011247:Pregnancy; D011859:Radiography; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery