Neuroendocrine aspects of chronic fatigue syndrome.
Chronic fatigue syndrome (CFS) is a serious health concern affecting over 800000 Americans of all ages, races, socioeconomic groups and genders. The etiology and pathophysiology of CFS are unknown, yet studies have suggested an involvement of the neuroendocrine system. A symposium was organized in March 2001 to explore the possibility of an association between neuroendocrine dysfunction and CFS, with special emphasis on the interactions between neuroendocrine dysfunction and other abnormalities noted in the immune and autonomic nervous systems of individuals with CFS. This paper represents the consensus of the panel of experts who participated in this meeting.
Papanicolaou
Dimitris A
DA
Department of Medicine/Endocrinology, Emory University, Atlanta, GA, USA.
Amsterdam
Jay D
JD
Levine
Susan
S
McCann
Samuel M
SM
Moore
Rebecca C
RC
Newbrand
Clare H
CH
Allen
Glen
G
Nisenbaum
Rosane
R
Pfaff
Donald W
DW
Tsokos
George C
GC
Vgontzas
Alexandros N
AN
Kales
Anthony
A
D001341:Autonomic Nervous System / Q000378:metabolism / Q000503:physiopathology; D003863:Depression / Q000503:physiopathology; D015673:Fatigue Syndrome, Chronic / Q000378:metabolism* / Q000503:physiopathology*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism / Q000503:physiopathology; D007107:Immune System / Q000378:metabolism / Q000503:physiopathology; D009490:Neurosecretory Systems / Q000378:metabolism* / Q000503:physiopathology*; D012893:Sleep Wake Disorders / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D013312:Stress, Physiological / Q000150:complications / Q000276:immunology