Cell biology of the intracellular infection by Legionella pneumophila.
Legionella pneumophila has become a paradigm for facultative intracellular pathogens that modulate biogenesis of their phagosomes into replicative niches. The ability to alter host cell biology and tailor it into a hospitable host for intracellular proliferation is at the crux of the mechanism of pathogenesis of Legionnaires' disease.
Molmeret
Maëlle
M
Department of Microbiology and Immunology, University of Louisville College of Medicine, Louisville, KY 40292, USA.
Bitar
Dina M
DM
Han
Lihui
L
Kwaik
Yousef Abu
YA
D000818:Animals; D017209:Apoptosis; D001426:Bacterial Proteins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D002455:Cell Division / Q000502:physiology; D056890:Eukaryota / Q000382:microbiology / Q000502:physiology; D005057:Eukaryotic Cells / Q000469:parasitology / Q000473:pathology; D006801:Humans; D016952:Legionella pneumophila / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D007877:Legionnaires' Disease / Q000209:etiology* / Q000382:microbiology; D008565:Membrane Proteins / Q000235:genetics; D009336:Necrosis; D014774:Virulence
D001426:Bacterial Proteins; D002352:Carrier Proteins; C440002:DotA protein, Legionella pneumophila; D008565:Membrane Proteins