title: Does umbilical cord care in preterm infants influence cord bacterial colonization or detachment?
abstract: OBJECTIVE
  The purpose of the present study was to compare alcohol versus natural drying for umbilical cord care in preterm infants and to examine its effects on bacterial colonization and cord detachment.
  
  
  METHODS
  Eligible infants <34 weeks gestation admitted to the NICU were randomized to receive either umbilical cleansing with 70% isopropyl alcohol at each diaper change or natural drying. Umbilical stump cultures were performed at 12 to 24 hours, 72 hours, 7 days, and 14 days of age.
  
  
  RESULTS
  A total of 109 infants were enrolled; 102 completed the study. Analyses revealed that the median cord detachment time was significantly shorter in the natural drying group compared to the alcohol group (13.0 versus 16.0 days; p=0.003). There were no cases of local umbilical infection in either group.
  
  
  CONCLUSIONS
  Based on the present study, it appears that natural drying is a safe and effective means of umbilical cord care in preterm infants.
authors.affiliation: Lutheran General Children's Hospital, Park Ridge, IL 60068, USA.
authors.forename: Kelley
authors.initials: K
authors.lastname: Evens
authors.forename: Jeffrey
authors.initials: J
authors.lastname: George
authors.forename: Denise
authors.initials: D
authors.lastname: Angst
authors.forename: Lorene
authors.initials: L
authors.lastname: Schweig
mesh_terms: D019840:2-Propanol / Q000008:administration & dosage*; D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011446:Prospective Studies; D014470:Umbilical Cord / Q000187:drug effects / Q000382:microbiology*; D014472:Umbilicus / Q000382:microbiology; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000517:prevention & control*
chemical_list: D000891:Anti-Infective Agents, Local; D019840:2-Propanol