title: Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line.
abstract: Five new maleic and succinic acid derivatives were isolated from the mycelium of Antrodia camphorata. Their structures were determined by various spectroscopic means. Maleimide derivatives 2 and 3 showed appreciable cytotoxic activity against LLC cells.
authors.affiliation: Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Nakamura
authors.forename: Akiko
authors.initials: A
authors.lastname: Hirakawa
authors.forename: Jiang-Jing
authors.initials: JJ
authors.lastname: Gao
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kakuda
authors.forename: Motoo
authors.initials: M
authors.lastname: Shiro
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Chia-chin
authors.initials: CC
authors.lastname: Sheu
authors.forename: Masao
authors.initials: M
authors.lastname: Hattori
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D008298:Maleates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D011124:Polyporaceae / Q000737:chemistry*; D019802:Succinic Acid / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013624:Taiwan; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D008298:Maleates; C030272:maleic acid; D019802:Succinic Acid