title: Java-based application framework for visualization of gene regulatory region annotations.
abstract: BACKGROUND
  The genome sequences of several organisms are either complete, or being sequenced. Each genome needs to be integrated with various types of annotations, e.g. locations of genes, promoters and other functional elements such as transcriptional regulatory elements. A robust application framework will be useful for developing web-based applications to visualize various genome annotations.
  
  
  RESULTS
  We developed genome data visualization toolkit (GDVTK) as an application framework that consists of a set of data structures and core classes, using Java technology. GDVTK is a sound framework for developing web-based applications to present the gene regulatory region annotations in visual form. The current version of GDVTK consists of eight packages and 38 Java classes that are portable, reusable and extensible for plugging in new data sources and models. We implemented GDVTK for visualization of promoter annotations in Mammalian Promoter Database (MPromDb), a web-based gene-regulatory information server.
  
  
  BACKGROUND
  GDVTK is available under GNU general public license. Source code and software documentation can be found at the URL http://bioinformatics.med.ohio-state.edu/GDVTK.
authors.affiliation: Human Cancer Genetics Program, Comprehensive Cancer Center, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, 420 W 12th Avenue, TMRF 524, Columbus, OH 43210, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Sun
authors.forename: Ramana V
authors.initials: RV
authors.lastname: Davuluri
mesh_terms: D003196:Computer Graphics; D003628:Database Management Systems; D030541:Databases, Genetic; D004282:Documentation; D019146:Hypermedia; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D011381:Programming Languages; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*; D012984:Software; D014584:User-Computer Interface