[Measurement of cerebral blood oxygen saturation with near infrared spectroscopy and its application in hypergravity].
OBJECTIVE
To measure the oxygen saturation of blood in rat's brain non-invasively after acceleration with near infrared spectroscopy technique.


METHODS
A serious of model about different ischemia and hypoxia of head, measured oxygen saturation by phlebotomize were made, and the difference with normal group was obtained. Its absorption intensity was measured and a curve showing the difference between the normal value was drawn. According to the curve, cerebral blood oxygen saturation after acceleration was calculated with the measured absorption intensity after high or push-pull maneuver by near infrared spectroscopy.


RESULTS
Compared high +Gz and push pull effect group with 0 Gz group, the content of ox hemoglobin reduced, in opposition the deox hemoglobin increased, the greater the difference, the lower the content of oxygen saturation of blood.


CONCLUSIONS
Oxygen saturation of blood in the rat's brain can be obtained non-invasively with near infrared spectroscopy.
Sun
Jia-shi
JS
Jilin Military Medical college, The Fourth Military Medical University, Jilin, China.
Tong
We-ge
WG
Chen
Mo-ran
MR
Xiao
Zhi-wei
ZW
D000054:Acceleration; D000818:Animals; D001923:Brain Chemistry; D018471:Hypergravity / Q000009:adverse effects*; D002534:Hypoxia, Brain / Q000097:blood* / Q000209:etiology / Q000378:metabolism; D023421:Models, Animal; D010100:Oxygen / Q000097:blood* / Q000378:metabolism; D010108:Oxyhemoglobins / Q000032:analysis* / Q000378:metabolism; D051381:Rats; D019265:Spectroscopy, Near-Infrared; D014474:Unconsciousness / Q000209:etiology
D010108:Oxyhemoglobins; D010100:Oxygen