Synthesis of the putative structure of eupomatilone-6.
[reaction: see text] The synthesis of eupomatilone-6 (1) has been achieved by using Suzuki coupling, Sharpless asymmetric dihydroxylation, and intramolecular Horner-Wadsworth-Emmons reactions. The spectroscopic studies carried out on synthetic eupomatilone-6 do not agree with those reported for the natural product, and therefore revision of the assigned structure is warranted.
Gurjar
Mukund K
MK
National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India. gurjar@dalton.ncl.res.in
Cherian
Joseph
J
Ramana
C V
CV
D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D008031:Lignin / Q000138:chemical synthesis* / Q000737:chemistry*; D019684:Magnoliopsida / Q000737:chemistry; D015394:Molecular Structure
D001572:Benzofurans; C485126:eupomatilone-6; D008031:Lignin