Strategies for intervention in and prevention of biofilm-related infection in peritoneal dialysis patients.
Bacteria from the exit site of the peritoneal dialysis (PD) catheter and from contaminated dialysis fluids can grow into microcolonies in biofilm. Those bacteria are implicated in recurrent peritonitis in patients undergoing treatment with PD. The present article highlights new strategies that are designed to alter the major factors regulating biofilm formation and that thereby reduce biofilm-related infections in PD patients.
Dasgupta
Mrinal K
MK
University of Alberta, Edmonton, Alberta, Canada. mkdg@ualberta.ca
D001424:Bacterial Infections / Q000517:prevention & control*; D001672:Biocompatible Materials; D018441:Biofilms / Q000187:drug effects; D002408:Catheters, Indwelling; D006801:Humans; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000382:microbiology / Q000517:prevention & control*; D012008:Recurrence
D001672:Biocompatible Materials