[Chemical composition and cryoprotective activity of ethanol extract from winter caterpillars Aporia crataegi L].
Glycerol, alpha-carotene, and other yet unidentified compounds have been found in the ethanol extract from winter caterpillars of the black-veined white (Aporia crataegi L.). We have shown that the ethanol extract has a cryoprotective effect on human peripheral blood lymphocytes, and this activity is approximately three times higher than that of glycerol (particularly, in the case of repeated freezing), which is one of the best cryoprotectors.
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Institute of Permafrost Biological Problems, Siberian Division, Russian Academy of Sciences, Leninskii pr. 41, Yakutsk, 677089 Russia.
Osakovskiĭ
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VL
Ivanova
S S
SS
D000818:Animals; D001679:Biogenic Amines / Q000302:isolation & purification / Q000494:pharmacology; D001793:Blood Preservation; D002080:Butterflies / Q000737:chemistry*; D002338:Carotenoids / Q000302:isolation & purification / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D027825:Crataegus; D015925:Cryopreservation; D003451:Cryoprotective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000431:Ethanol / Q000737:chemistry; D005615:Freezing; D005990:Glycerol / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000502:physiology; D012621:Seasons; D014020:Tissue Extracts / Q000302:isolation & purification / Q000494:pharmacology*
D001679:Biogenic Amines; D003451:Cryoprotective Agents; D014020:Tissue Extracts; D002338:Carotenoids; D000431:Ethanol; C041635:alpha-carotene; D005990:Glycerol