title: Synthesis of alkylated aminofluorenes by palladium-catalyzed substitution at halofluorenes.
abstract: New N-substituted 2-amino-9,9-dialkylfluorenes optionally bearing electron-withdrawing substituents such as nitro or cyano in position 7 can be synthesized starting from 2-halo-9,9-dialkylfluorenes by Pd-catalyzed substitution with amines. Chiral amino groups can be introduced by this method too. 2-N,N-Dimethylamino-7-nitro-9H-fluorene was obtained in a convenient way by reductive amination. The N-substituted 2-amino-7-nitro-9H-fluorenes are promising candidates for fluorescence probes for femtosecond solvation dynamics.
authors.affiliation: Department of Chemistry, Humboldt University, Brook-Taylor Strasse 2, 12489 Berlin, Germany liebscher@chemie.hu-berlin.de
authors.forename: Ginagunta
authors.initials: G
authors.lastname: Saroja
authors.forename: Zhang
authors.initials: Z
authors.lastname: Pingzhu
authors.forename: Nikolaus P
authors.initials: NP
authors.lastname: Ernsting
authors.forename: Jürgen
authors.initials: J
authors.lastname: Liebscher