title: [Clinical analysis of orbital histocytosis X].
abstract: OBJECTIVE
  To study the clinical and imaging features together with diagnosis and management of orbital histocytosis X.
  
  
  METHODS
  In a retrospective study from 1973 to 1999, 47 cases of histocytosis X were reviewed related with clinical materials, including eosinophilic granuloma 17 cases and Hand-Schuller- Christian disease 30 cases.
  
  
  RESULTS
  Most occur in children and teenagers, mainly in male. Characteristic clinical features, roentgenography, ultrasonography, CT, MRI provide the most diagnostic assistance.
  
  
  CONCLUSIONS
  Solitary unifocal eosinophilic granuloma mainly involves teenagers. Hand-Schuller-Christian disease usually take places between birth and 5 years of age, which is characterized by multifocal variant of eosinophilic granuloma, especially the classic triad. Characteristic images contribute to the diagnosis. Multiple management is needed, including surgery, chemotherapy and radiotherapy. The prognosis varies with the three types.
authors.affiliation: Tianjin Orbit Institute, Department of Ophthalmology, The Second Affiliated Hospital, Tianjin Medical University, Tianjin 300211, China. zxdeye@sina.com
authors.forename: Xiao-dong
authors.initials: XD
authors.lastname: Zhou
authors.forename: Guo-xiang
authors.initials: GX
authors.lastname: Song
authors.forename: Yan-jin
authors.initials: YJ
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009916:Orbital Diseases / Q000175:diagnosis*; D011379:Prognosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed