Nucleophilic partners in the tandem conjugate addition-Dieckmann condensation reaction: 1. synthesis of 1,2,3-trisubstituted naphthalenes.
The scope and limitations of the tandem conjugate addition-Dieckmann condensation for the construction of 1,2,3-trisubstituted naphthalenes is defined. Viable nucleophilic partners in this methodology include organocuprates, active methylenes, and a variety of heteroatom initiators.
Martinez
Aaron D
AD
Department of Chemistry MS-60 Rice University, Houston, Texas 77251-1892, USA.
Deville
Jay P
JP
Stevens
Joel L
JL
Behar
Victor
V