title: The use of sentinel lymph node biopsy in squamous cell carcinoma of the foot: a case report.
abstract: Squamous cell carcinoma (SCC) is the second most common skin cancer in humans. Because the incidence of metastasis from SCC of the skin is rare, regional lymphadenectomy is generally not recommended for the patients with clinically node-negative disease. However, in patients with an intermediate and high risk of metastasis, evaluation of the lymph nodes to detect the absence of metastatic nodal disease is a difficult task. Here, we present a patient with a large SCC on the dorsum of the foot with clinically negative inguinal and popliteal lymph nodes. Intraoperative lymphatic mapping technique was used to make the decision of the inguinal node dissection. Two sentinel lymph nodes that were biopsy negative were found; therefore, only tumor excision was performed without adding complete inguinal node dissection. The defect was reconstructed with the free flap. After a 4-year carcinoma-free period, we determined that the pathology of the sentinel lymph nodes reflected that of the inguinal region. The use of selective lymphadenectomy technique in extremity SCC is very new. However, it might be useful in staging patients with SCC of the lower extremity by being able to detect absence or presence of occult metastatic nodal disease and avoid unnecessary complete inguinal node dissection.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Sişli Etfal State Hospital, Istanbul, Turkey. deryaozcelik68@yahoo.com
authors.forename: Derya
authors.initials: D
authors.lastname: Ozçelik
authors.forename: Soner
authors.initials: S
authors.lastname: Tatlidede
authors.forename: Semra
authors.initials: S
authors.lastname: Hacikerim
authors.forename: Kemal
authors.initials: K
authors.lastname: Uğurlu
authors.forename: Murat
authors.initials: M
authors.lastname: Atay
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005528:Foot / Q000473:pathology* / Q000601:surgery; D005534:Foot Diseases / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy; D013524:Surgical Flaps