Cognitive and emotional dysfunction after central pontine myelinolysis.
The case of a 67-year-old right-handed Chinese man with Central Pontine Myelinolysis [CPM] is described to illustrate the resulting cognitive and emotional disturbances. A comparison of the data in this report with that in published studies suggests that ethnicity does not seem to have much effect on the symptoms of CPM. Possible underlying neural-pathological mechanisms are discussed. This case further substantiates the speculation that the brainstem plays a role in higher cognitive processes and emotional regulation.
Lee
Tatia M C
TM
Neuropsychology Laboratory, Department of Psychology, The University of Hong Kong, Hong Kong SAR. tmclee@hkusua.hku.hk
Cheung
Crystal C Y
CC
Lau
Esther Y Y
EY
Mak
Amanda
A
Li
Leonard S W
LS
D000342:Affective Symptoms / Q000175:diagnosis / Q000209:etiology*; D000368:Aged; D001921:Brain / Q000473:pathology; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000150:complications* / Q000175:diagnosis; D009483:Neuropsychological Tests; D012720:Severity of Illness Index