Endothelin expression and the progression of heart failure: exemplifying the vagaries of therapeutic development.
Konstam
Marvin A
MA
Division of Cardiology, Department of Medicine, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Mass, USA. mkonstam@tufts-nemc.org
DeNofrio
David
D
D000818:Animals; D018450:Disease Progression; D065130:Endothelin A Receptor Antagonists; D019332:Endothelin-1 / Q000378:metabolism* / Q000502:physiology; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008955:Models, Cardiovascular; D012084:Renin-Angiotensin System; D020257:Ventricular Remodeling
D065130:Endothelin A Receptor Antagonists; D019332:Endothelin-1