title: In situ monitoring of metal nanoparticle self-assembly on protein-functionalized glass by broadband optical waveguide spectroscopy.
abstract: Broadband, time-resolved optical waveguide (OWG) spectroscopy has been used for in situ, real-time investigation into the self-assembly of metal nanoparticle monolayers. The OWG spectroscopy makes it possible to use the transverse electric (TE) and transverse magnetic (TM) modes to measure surface plasmon absorption of immobilized metal nanoparticles in two directions, parallel and normal to the waveguide surface. Therefore, this technique can provide direction-dependent information on the metal nanoparticles at the interface. In this paper, a 50-microm-thick glass plate was used as a slab waveguide and the kinetics of Au nanoparticle adsorption on a hemoglobin-functionalized glass substrate was examined in the early stage of self-assembly. The findings show that with the TE mode the surface plasmon resonance (SPR) behavior for immobilized Au nanoparticles is different from that with the TM mode.
authors.affiliation: Nanoarchitectonics Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba 305-8565, Japan.
authors.forename: Zhi-mei
authors.initials: ZM
authors.lastname: Qi
authors.forename: Naoki
authors.initials: N
authors.lastname: Matsuda
authors.forename: Jose
authors.initials: J
authors.lastname: Santos
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Yoshida
authors.forename: Akiko
authors.initials: A
authors.lastname: Takatsu
authors.forename: Kenji
authors.initials: K
authors.lastname: Kato
mesh_terms: D005898:Glass / Q000737:chemistry*; D017979:Gold Colloid / Q000737:chemistry*; D006454:Hemoglobins / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size; D013057:Spectrum Analysis / Q000379:methods*
chemical_list: D017979:Gold Colloid; D006454:Hemoglobins