[Expression of epidermal growth factor receptor and its ligands in other malignant tumor pathologies].
The aim of this review was to describe expression of epithelial growth factor receptor (EGFR) and of its ligands in a panel of tumours (which are not specified elsewhere in this special issue of Bulletin du Cancer): squamous cell carcinomas, adenocarcinomas, sarcomas, brain and germ line tumours. The role of EGFR and its ligands in the carcinogenesis and the progression of these tumours, as well as the relevance of targeting EGFR.
Bosq
Jacques
J
Département de pathologie, Institut Gustave-Roussy, rue Camille-Desmoulins, 94805 Villejuif. bosq@igr.fr
Penault-Llorca
Frédérique
F
Sabourin
Jean-Claude
JC
D000230:Adenocarcinoma / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000378:metabolism*; D066246:ErbB Receptors / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D009363:Neoplasm Proteins / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism*; D012509:Sarcoma / Q000378:metabolism; D016211:Transforming Growth Factor alpha / Q000378:metabolism
D009363:Neoplasm Proteins; D016211:Transforming Growth Factor alpha; D066246:ErbB Receptors