title: [Prolonged hepatitis A: three case reports].
abstract: In this report, three patients, admitted to Ankara University Faculty of Medicine, Ibni Sina Hospital, Clinical Bacteriology and Infectious Diseases Department, with the diagnosis of acute viral hepatitis A have been discussed because of their clinical and/or biochemical relapses. Following conservative treatment and bedrest, the liver transaminases decrease to nearly normal levels but a second peak was observed later in three of the cases. Other viral, metabolic and autoimmune factors which could lead to the increase of liver transaminases were ruled out. Anti-HAV IgM antibodies became negative in 2 to 4 months later, and liver enzymes returned to normal in 4 to 5 months after onset of their illnesses. As a result, it was concluded that conservative follow-up and therapy would be sufficient since the prognosis of A hepatitis is usually benign even if it relapsed.
authors.affiliation: Ankara Universitesi Tip Fakültesi, Klinik Bakteriyoloji ve Infeksiyon Hastaliklari Anabilim Dali Ankara.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Yeşilkaya
authors.forename: Gizem
authors.initials: G
authors.lastname: Demir
authors.forename: K Osman
authors.initials: KO
authors.lastname: Memikoğlu
authors.forename: Fügen
authors.initials: F
authors.lastname: Cokça
authors.forename: Tuncay Hasip
authors.initials: TH
authors.lastname: Sözen
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D006506:Hepatitis A / Q000175:diagnosis* / Q000628:therapy; D035922:Hepatitis A Antibodies / Q000097:blood; D006801:Humans; D008099:Liver / Q000201:enzymology; D008297:Male; D011379:Prognosis; D012008:Recurrence; D000637:Transaminases / Q000097:blood
chemical_list: D035922:Hepatitis A Antibodies; D000637:Transaminases