title: [Sleep disorders in temporal lobe epilepsy].
abstract: The objective of this study was to evaluate sleep macrostructure and sleep disturbance in a group of 39 patients with temporal lobe epilepsy (TLE). Patients completed questionnaires to evaluate their sleep and subjective daytime sleepiness (Epworth Sleepiness Scale [ESS]) and undergone Polysomnography and Multiple Sleep Latency Test (MSLT). Daytime sleepiness was the most frequent complaint (85%), followed by wakefulness during sleep, history of seizures during sleep (75%) and initial insomnia (26%). Parasomnias (67%), obstructive sleep apneas (13%), restless legs syndrome (15%) and periodic limb movements (5%) were the most frequent sleep disorders. The most frequent changes of sleep patterns were: sleep architecture fragmentation (100%), decreased amount of REM sleep (92%) and increase in time awake after sleep onset (77%). There were significative correlations between the ESS and the MSLT (p<0,05). In conclusion, TLE patients have fragmented sleep with increased sleep stages shifts, increased number of awakenings and in time awake after sleep onset. REM sleep was decreased. Daytime sleepiness was the most frequent complaint in TLE patients.
authors.affiliation: Servi o de Neurologia e Neurocirurgia, Departamento de Neuropsiquiatria, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife PE, Brasil. claudiangela@hotmail.com
authors.forename: Cláudia Angela Vilela
authors.initials: CA
authors.lastname: de Almeida
authors.forename: Otávio Gomes
authors.initials: OG
authors.lastname: Lins
authors.forename: Salustiano Gomes
authors.initials: SG
authors.lastname: Lins
authors.forename: Sílvia
authors.initials: S
authors.lastname: Laurentino
authors.forename: Marcelo Moraes
authors.initials: MM
authors.lastname: Valença
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000927:Anticonvulsants / Q000009:adverse effects; D002940:Circadian Rhythm; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011930:Reaction Time; D017678:Sex Distribution; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D012894:Sleep Stages / Q000187:drug effects / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000503:physiopathology*; D012895:Sleep, REM / Q000502:physiology; D014851:Wakefulness
chemical_list: D000927:Anticonvulsants