title: Survival of cervix cancer patients in Harare, Zimbabwe, 1995-1997.
abstract: The survival experience of 284 patients with cancer of the cervix uteri registered by the population-based Zimbabwe National Cancer Registry in 1995-1997 is described. The vital status of these subjects was established by linkage with death registration and by retrieval of patient files from medical records departments. Untraced patients were contacted at home. Of the 284, 177 (62.3%) were dead and 76 (26.8%) were alive at the closing date of the study (31 December 1999), with only 31 cases (10.9%) lost to follow-up. Overall observed and relative survival at 3 years were 44.2% and 45.2%, respectively. Half of the cases (139) had been referred and treated in the radiotherapy department. Survival was significantly greater in the first 3 years for patients who received radiotherapy treatment compared to those that had not, but this difference had disappeared by the fourth year of follow-up. Many cases presented late (distant metastasis), and extent of disease was an important determinant of survival; cases with metastases had a risk of death some 3 times that of patients with localized disease. The results demonstrate the importance of earlier diagnosis and availability of effective treatment in the African context.
authors.affiliation: Zimbabwe National Cancer Registry, Harare, Zimbabwe.
authors.forename: Eric
authors.initials: E
authors.lastname: Chokunonga
authors.forename: Agnihotram V
authors.initials: AV
authors.lastname: Ramanakumar
authors.forename: Anna M
authors.initials: AM
authors.lastname: Nyakabau
authors.forename: Margaret Z
authors.initials: MZ
authors.lastname: Borok
authors.forename: Z Michael
authors.initials: ZM
authors.lastname: Chirenje
authors.forename: Risto
authors.initials: R
authors.lastname: Sankila
authors.forename: D Maxwell
authors.initials: DM
authors.lastname: Parkin
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000532:radiotherapy; D015030:Zimbabwe / Q000453:epidemiology