title: InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium.
abstract: The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol and that it is required for its transport via the SPI-1 TTSS.
authors.affiliation: Institute of Microbiology, ETH Zürich, 8092 Zürich, Switzerland.
authors.forename: Kristin
authors.initials: K
authors.lastname: Ehrbar
authors.forename: Siegfried
authors.initials: S
authors.lastname: Hapfelmeier
authors.forename: Bärbel
authors.initials: B
authors.lastname: Stecher
authors.forename: Wolf-Dietrich
authors.initials: WD
authors.lastname: Hardt
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D003600:Cytosol / Q000378:metabolism; D021381:Protein Transport; D012486:Salmonella typhimurium / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; C088597:invB protein, Salmonella; C060971:SopA protein, Bacteria