title: Low-grade myofibroblastic sarcoma of the vulva.
abstract: BACKGROUND
  Vulvar sarcomas are rare tumors. A distinctive low-grade myofibroblastic sarcoma is described.
  
  
  METHODS
  A 46-year-old female presented with a progressively enlarging vulvar mass. Pathological evaluation revealed a low-grade myofibroblastic sarcoma. The immunophenotype is outlined and ultrastructural features are highlighted. Tumor cells were positive for p53 protein, smooth muscle actin, steroid receptors, and showed myofibroblastic differentiation on electron microscopy. The patient has been followed for >14 months without evidence of recurrence.
  
  
  CONCLUSIONS
  The tumor was positive for p53, mitotically active, but was categorized as a low-grade malignancy. Immunohistochemical and ultrastructural criteria were utilized to distinguish this tumor from other neoplasms.
authors.affiliation: Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS 39206, USA. Troth@jam.rr.com
authors.forename: Ted M
authors.initials: TM
authors.lastname: Roth
authors.forename: Jonathan
authors.initials: J
authors.lastname: Fratkin
authors.forename: T Casey
authors.initials: TC
authors.lastname: Woodring
authors.forename: Ramon P
authors.initials: RP
authors.lastname: McGehee
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009217:Myosarcoma / Q000378:metabolism / Q000473:pathology*; D011987:Receptors, Steroid / Q000096:biosynthesis; D016159:Tumor Suppressor Protein p53 / Q000096:biosynthesis; D014846:Vulvar Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: D011987:Receptors, Steroid; D016159:Tumor Suppressor Protein p53