title: Establishing the synthetic origin of amphetamines by 2H NMR spectroscopy.
abstract: Nine samples of N-acetyl-3,4-methylenedioxyamphetamine (N-acetyl-MDA), prepared according to the most common synthetic procedures, are submitted to (2)H NMR spectroscopy. The relative deuterium content at the various sites of the molecule is shown to depend on its synthetic history. The technique provides a chemical fingerprint of N-acetyl-MDAs and it can be used to trace back the precursor materials and the synthetic pathways employed in the preparation of the samples.
authors.affiliation: Dipartimento di Chimica, Materiali, Ingegneria Chimica, Politecnico di Milano, ed Istituto CNR per la Chimica del Riconoscimento Molecolare, Via Mancinelli 7, I-20131 Milano, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Armellin
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Brenna
authors.forename: Giovanni
authors.initials: G
authors.lastname: Fronza
authors.forename: Claudio
authors.initials: C
authors.lastname: Fuganti
authors.forename: Matteo
authors.initials: M
authors.lastname: Pinciroli
authors.forename: Stefano
authors.initials: S
authors.lastname: Serra
mesh_terms: D003903:Deuterium / Q000032:analysis; D004335:Drug and Narcotic Control / Q000379:methods; D013287:Illicit Drugs / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D013287:Illicit Drugs; D003903:Deuterium; D018817:N-Methyl-3,4-methylenedioxyamphetamine