Angiostrongylus costaricensis and experimental infection of Sarasinula marginata II: elimination routes.
Angiostrongylus costaricensis intermediate hosts are terrestrial mollusks mostly belonging to the Veronicellidae family. In the present investigation we focused on the mechanisms of larval expulsion from Sarasinula marginata infected with A. costaricensis. Twenty-five mollusks were individually infected with 5000 L1 and sacrificed at 30 min and 1, 2, 4, 6, and 8 h post-infection and at days 1, 2, 4, 5, 6, 8, 10, 11, 12, 14, 15, 16, 20, 21, 22, 25, 26, 28, and 30 post-infection; the mollusks were then fixed and stained. Diverse organs involved throughout the course of the migratory routes of larvae from oral penetration on were specified and the mechanisms of larval access to the fibromuscular layer through the kidney, rectum, and vascular system were defined. The elimination of L3, derived from oral and/or cutaneous infections, appears to depend on granulomas located close to the excretory ducts of mucous cells.
Mendonça
Cristiane Lafeta Gomes Furtado
CL
Centro de Pesquisas Ren  Rachou, Fiocruz, Belo Horizonte, MG, Brasil.
Carvalho
Omar Santos
OS
Mota
Ester Maria
EM
Pelajo-Machado
Marcelo
M
Caputo
Luzia Fátima Gonçalves
LF
Lenzi
Henrique Leonel
HL
D000801:Angiostrongylus / Q000502:physiology*; D000818:Animals; D006790:Host-Parasite Interactions; D008974:Mollusca / Q000469:parasitology*; D013997:Time Factors