title: Radiofrequency catheter ablation in small children: relationship of complications to application dose.
abstract: Little data exists to support the use of procedural modifications during radiofrequency catheter ablation (RFCA) in small children. A single institution database was reviewed for patients under 15 kg undergoing RFCA from January 1998 to August 2001. Of 268 RFCA procedures, 18 were done in 14 patients under 15 kg (median weight 5.7 kg, 3.5-13.7; age 5.8 months, 1.2-19.8). Six patients had normal hearts, 4 had congenital heart disease, and 4 patients had cardiomyopathy. Diagnoses were orthodromic reciprocating tachycardia (ORT) in nine patients/nine studies, chaotic atrial tachycardia (CAT) in one patient/two studies, and VT in four patients/seven studies. RFCA variables included maximum temperature (69 degrees C, 50-78), total applications (10, 2-21), applications > 20 seconds (5, 0-15), and total application time (331 s, 26-1,006 s). Complications were pericardial effusion in 1 patient, mild mitral regurgitation in 1, and myocardial infarction in 1 patient. When indexed for weight, the number of applications with a duration > 20 seconds in the ORT group was significantly greater in complicated versus uncomplicated procedures (0.7 applications/kg vs 0.16 applications/kg, P = 0.05). In addition, for the ORT subgroup, the indexed total application time trended higher in complicated versus uncomplicated procedures (40.6 s/kg, vs 6.6 s/kg, P = 0.1). RFCA success was 9/9 in ORT, 6/7 in VT, and 0/2 in CAT. RFCA can be successful in small children; however, complications appear to be related to RF dose indexed for body size. Thus, the decision to proceed with RFCA, and the application duration and number should be guided by patient size, balanced against the risks of the arrhythmia, and reserved for dire circumstances.
authors.affiliation: Children's Heart Program of South Carolina, Medical University of South Carolina, Charleston, South Carolina 29425, USA. Blaufoad@musc.edu
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Blaufox
authors.forename: Thomas
authors.initials: T
authors.lastname: Paul
authors.forename: J Philip
authors.initials: JP
authors.lastname: Saul
mesh_terms: D001835:Body Weight; D009202:Cardiomyopathies / Q000150:complications; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D008944:Mitral Valve Insufficiency / Q000209:etiology; D009203:Myocardial Infarction / Q000209:etiology; D010490:Pericardial Effusion / Q000209:etiology; D011183:Postoperative Complications; D012189:Retrospective Studies; D013610:Tachycardia / Q000601:surgery; D017180:Tachycardia, Ventricular / Q000601:surgery; D013696:Temperature; D013997:Time Factors; D016896:Treatment Outcome