Generation of strong, homochiral bases by electrochemical reduction of phenazine derivatives.
Electrochemical reduction of enantiomerically pure amino- and alkoxy-phenazine derivatives forms strongly basic radical anions which give asymmetric induction in the conversion of 3,4-epoxytetrahydrothiophene-1,1-dioxide into the allylic ester with facile regeneration of the phenazine.
Alonso
A Mateo
AM
Department of Chemistry, Queen Mary, University of London, Mile End Road, London E1 4NS, UK.
Horcajada
Roberto
R
Groombridge
Helen J
HJ
Mandalia
Reshma
R
Motevalli
Majid
M
Utley
James H P
JH
Wyatt
Peter B
PB