Highly enantioselective spiro cyclization of 1,6-enynes catalyzed by cationic skewphos rhodium(I) complex.
A cationic rhodium(I) complex having a skewphos ligand is shown to be a highly enantioselective catalyst for asymmetric carbocyclization of 1,6-enynes with tri-substituted olefins to control quaternary stereogenic centers of spiro-rings.
Mikami
Koichi
K
Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo, 152-8552, Japan. kmikami@o.cc.titech.ac.jp
Yusa
Yukinori
Y
Hatano
Manabu
M
Wakabayashi
Kazuki
K
Aikawa
Kohsuke
K