Human herpes virus-8-negative primary effusion lymphoma in a patient with common variable immunodeficiency.
Primary effusion lymphoma (PEL) is a newly described high-grade B cell lymphoma developing in association with human herpes virus type 8 (HHV-8) in human immunodeficiency virus (HIV)-infecting individuals. Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by reduced serum immunoglobulin and heterogeneous clinical features. The risk of cancer in CVID patients is increased. Here, we describe a PEL that developed in the pleural and pericardial cavities of an HIV-negative and HHV-8-negative patient with CVID.
Hisamoto
Akiko
A
Departament of Medicine, Sumitomo-Besshi Hospital, 3-1 Ojicho, Niihama, Ehime 792-0008, Japan. fwpg0506@mb.infoweb.ne.jp
Yamane
Hiromichi
H
Hiraki
Akio
A
Maeda
Yoshinobu
Y
Fujii
Nobuharu
N
Sasaki
Kenji
K
Miyake
Toshitugu
T
Sasaki
Takashi
T
Nakamura
Tohru
T
Kiura
Katsuyuki
K
Tanimoto
Mitsune
M
Kamei
Haruhito
H
D017074:Common Variable Immunodeficiency / Q000175:diagnosis*; D005260:Female; D018023:HIV Seronegativity; D006566:Herpesviridae Infections / Q000821:virology*; D019288:Herpesvirus 8, Human; D006801:Humans; D007564:Japan; D008223:Lymphoma / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D016066:Pleural Effusion, Malignant / Q000209:etiology* / Q000473:pathology; D010997:Pleural Neoplasms / Q000209:etiology* / Q000473:pathology