Fine-needle aspiration biopsy diagnosis of intrathoracic extramedullary hematopoiesis presenting as a posterior mediastinal tumor in a patient with sickle-cell disease: Case report.
Extramedullary hematopoiesis (EMH) is a rare cause of an intrathoracic mass. Fine-needle aspiration biopsy (FNAB) has been only occasionally documented as a useful tool in diagnosing EMH tumor. We report a case of posterior mediastinal extramedullary hematopoietic mass in an 80-yr-old man with sickle-cell anemia. The mass was revealed incidentally on chest X-ray. The definitive diagnosis of this mass lesion was achieved by FNAB. The cytologic smears showed hematopoietic elements with erythroid hyperplasia. A correct cytologic diagnosis can thus help to avoid unnecessary surgical intervention, particularly in an asymptomatic patient.
Al-Marzooq
Yusef M
YM
Department of Pathology, King Fahad Hospital, Hofuf, Al-Hassa, Saudi Arabia. ymarz@hotmail.com
Al-Bahrani
Ahmed T
AT
Chopra
Rajan
R
Al-Momatten
Mohmmed I
MI
D000368:Aged; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*; D035423:Thoracic Cavity / Q000473:pathology*