Pseudo-C3-symmetric trisoxazolines as ligands in copper catalyzed enantioselective Diels-Alder reaction.
Air- and water-stable chiral catalyst trisoxazolines4-6 /Cu(ClO(4))(2)[middle dot]6H(2)O have been used in the Diels-Alder reaction of cyclopentadiene with acryloyl-2-oxazolidinones or ketoesters. The reaction is carried out in air and up to 82% ee was achieved.
Zhou
Jian
J
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 354 Fenglin Lu, Shanghai 200032, China. tangy@mail.sioc.ac.cn
Tang
Yong
Y