A novel synthesis of chiral rotaxanes via covalent bond formation.
Chiral rotaxanes composed of the asymmetric crownophane incorporating two hydroxy groups as a rotor moiety and the asymmetric axis were effectively synthesized via covalent bond formation, i.e. tandem Claisen rearrangement, esterification, and aminolysis.
Kameta
Naohiro
N
Department of Applied Chemistry, Faculty of Engineering, Utsunomiya University, 7-1-2 Youtou, Utsunomiya 321-8585, Japan.
Hiratani
Kazuhisa
K
Nagawa
Yoshinobu
Y