Simple synthesis of beta-D-glycopyranosides using beta-glycosidase from almonds.
Enzymatic glycosidation of twenty-one kinds of alcohols (n-hepanol, n-octanol, 2-phenylethanol, 3-phenylpropanol, 4-phenylbutanol, 5-phenylpentanol, 6-phenylhexanol, furfury alcohol, 2-pyridinemethanol, isobutanol, isopentanol, p-methoxycinnamylalcohol) including secondary alcohols (isopropanol, cyclohexanol, 1-phenylethanol) and 1,omega-alkanediols (1,5-pentanediol, 1,6-hexanediol, 1,7-heptanediol, 1,8-octanediol, 1,9-nonanediol), salicyl alcohol and 4-nitrophenyl beta-D-glucopyranoside (5) using beta-glucosidase from almonds stereoselectively gave the corresponding beta-D-glucopyranosides in moderate yield.
Kurashima
Katsumi
K
Enzymes and Pharmaceuticals Research Laboratory, Godo Shusei Co, Ltd, Chiba, Japan.
Fujii
Mikio
M
Ida
Yoshiteru
Y
Akita
Hiroyuki
H
D000438:Alcohols / Q000737:chemistry; D005960:Glucosides / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009596:Nitrophenols / Q000737:chemistry; D027861:Prunus / Q000737:chemistry*; D013237:Stereoisomerism; D001617:beta-Glucosidase / Q000737:chemistry* / Q000302:isolation & purification
D000438:Alcohols; D005960:Glucosides; D009596:Nitrophenols; C024719:4-nitrophenyl; D001617:beta-Glucosidase