title: [Invasive hydatiform mole in a postmenopausal woman].
abstract: Gestational trophoblastic disease occurs rarely in postmenopausal women. We report the case of a 51 year-old postmenopausal woman with an invasive complete mole. Invasive mole should be distinguished from choriocarcinoma, by a thorough sampling showing infiltrative molar villi associated with a prominent trophoblastic proliferation. Gestational trophoblastic diseases in postmenopausal women can represent malignant changes of trophoblastic remnants of a prior pregnancy after a period of latency or correspond to a possible current pregnancy as demonstrated by an ovarian corpus luteum of pregnancy in our patient. The unusual finding in our case is that the gestational trophoblastic disease follows a pregnancy occurring after a biologically confirmed menopause.
authors.affiliation: Service d'anatomie et cytologie pathologiques, Hôpital de la Croix Rousse, Lyon.
authors.forename: Arnaud
authors.initials: A
authors.lastname: de  la Fouchardière
authors.forename: Alexandre
authors.initials: A
authors.lastname: Cassignol
authors.forename: Leila
authors.initials: L
authors.lastname: Benkiran
authors.forename: René Charles
authors.initials: RC
authors.lastname: Rudigoz
authors.forename: Alain
authors.initials: A
authors.lastname: Gougeon
authors.forename: Mojgan
authors.initials: M
authors.lastname: Devouassoux-Shisheboran
mesh_terms: D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000473:pathology* / Q000601:surgery; D007044:Hysterectomy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery; D017698:Postmenopause; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery