title: High prevalence of vitamin D insufficiency in healthy elderly people living at home in Argentina.
abstract: OBJECTIVE
  To evaluate the nutritional status of vitamin D in urban populations of healthy elderly people living at home, in different regions of Argentina.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  In total, 386 ambulatory subjects over 65 y of age from seven cities (between latitude 26 degrees S and 55 degrees S) were asked to participate between the end of winter and the beginning of spring. Of these, 369 accepted, 30 were excluded because of medical history or abnormal biochemical determinations. Finally, 339 subjects (226 women and 113 men) (X+/-s.d.) (71.3+/- 5.2 y) were included.
  
  
  RESULTS
  Serum 25OHD levels were lowest in the South (latitude range: 41 degrees S-55 degrees S): 14.2+/-5.6 ng/ml (P<0.0001vs North and Mid regions); highest in the North (26 degrees S-27 degrees S): 20.7+/-7.4 ng/ml (P<0.03 vs Mid, P<0.0001vs South); and intermediate in the Mid region (33 degrees S-34 degrees S) 17.9+/-8.2 ng/ml. Serum mid-molecule PTH (mmPTH) and 25OHD were inversely related: (r=-0.24, P<0.001). A cutoff level of 25OHD at which serum mmPTH levels began to increase was established at 27 ng/ml. A high prevalence (87-52%) of subjects with 25OHD levels in the deficiency-insufficiency range (25OHD levels <20 ng/ml) was detected.
  
  
  CONCLUSIONS
  This study shows that vitamin D deficiency/insufficiency in the elderly is a worldwide problem. Correction of this deficit would have a positive impact on bone health of elderly people.
authors.affiliation: Research Comitée of the Asociación Argentina de Osteología y Metabolismo Mineral, Sección Osteopatías Médicas, Hospital de Clínicas, Universidad de Buenos Aires, Buenos Aires, Argentina. osteologia@ciudad.com.ar
authors.forename: B
authors.initials: B
authors.lastname: Oliveri
authors.forename: L
authors.initials: L
authors.lastname: Plantalech
authors.forename: A
authors.initials: A
authors.lastname: Bagur
authors.forename: A C
authors.initials: AC
authors.lastname: Wittich
authors.forename: G
authors.initials: G
authors.lastname: Rovai
authors.forename: E
authors.initials: E
authors.lastname: Pusiol
authors.forename: J
authors.initials: J
authors.lastname: López Giovanelli
authors.forename: G
authors.initials: G
authors.lastname: Ponce
authors.forename: A
authors.initials: A
authors.lastname: Nieva
authors.forename: A
authors.initials: A
authors.lastname: Chaperón
authors.forename: M
authors.initials: M
authors.lastname: Ladizesky
authors.forename: J
authors.initials: J
authors.lastname: Somoza
authors.forename: C
authors.initials: C
authors.lastname: Casco
authors.forename: S
authors.initials: S
authors.lastname: Zeni
authors.forename: M S
authors.initials: MS
authors.lastname: Parisi
authors.forename: C A
authors.initials: CA
authors.lastname: Mautalen
mesh_terms: D000368:Aged / Q000502:physiology; D001118:Argentina / Q000453:epidemiology; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000097:blood*; D002980:Climate; D003430:Cross-Sectional Studies; D005260:Female; D005843:Geography; D006801:Humans; D008297:Male; D009749:Nutrition Surveys; D015995:Prevalence; D012111:Residence Characteristics; D012621:Seasons; D012737:Sex Factors; D013472:Sunlight; D014504:Urban Health / Q000706:statistics & numerical data; D014807:Vitamin D / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000145:classification / Q000453:epidemiology*
chemical_list: D002136:Calcium, Dietary; D014807:Vitamin D; C104450:25-hydroxyvitamin D