Studies of antimicrobial activity of N-alkyl and N-acyl 2-(4-thiazolyl)-1H-benzimidazoles.
Various N-alkyl and N-acyl derivatives of 2-(4-thiazolyl)-1H-benzimidazole, an anthelmintic and systemic fungicide, were synthesized by polymer-supported reactions and screened for their antifungal and antibacterial potency to establish structure-activity relationships.
Pawar
N S
NS
School of Chemical Sciences, North Maharashtra University, Jalgaon, 425 001, India. mahulikarpp@rediffmail.com
Dalal
D S
DS
Shimpi
S R
SR
Mahulikar
P P
PP
D000528:Alternaria / Q000187:drug effects; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D001407:Bacillus / Q000187:drug effects; D005670:Fusarium / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011108:Polymers / Q000737:chemistry; D011549:Pseudomonas / Q000187:drug effects; D013329:Structure-Activity Relationship; D013827:Thiabendazole / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D011108:Polymers; D013827:Thiabendazole