title: [Non-obstructive azoospermia: 2 new cases of Sertoli cell only syndrome].
abstract: OBJECTIVE
  We report 2 cases of Sertoli cell only syndrome and perform a bibliographic review.
  
  
  METHODS
  Clinical and pathologic study of 2 male patients 33 and 37-year-old respectively who presented with infertility.
  
  
  RESULTS
  Testicular biopsy, the most important diagnostic test in the study of infertile men, showed bilateral Sertoli cell only syndrome.
  
  
  CONCLUSIONS
  The Sertoli cell only syndrome is an entity in which seminiferous tubules show a total absence of germ cells with Sertoli cells alone. Etiology is unknown in most cases. Testicular biopsy is performed in these azoospermic men to rule out tubular obstruction or abnormalities of the spermatogenesis. Assisted reproduction techniques are a therapeutic option, making genetic counselling necessary due to the risk of transmission of the genetic defects that cause male infertility.
authors.affiliation: Servicio de Urología, Servicio de Genética, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: Antonio
authors.initials: A
authors.lastname: Jalón Monzón
authors.forename: José Luis
authors.initials: JL
authors.lastname: Martín Benito
authors.forename: Jorge
authors.initials: J
authors.lastname: García Rodríguez
authors.forename: Ana
authors.initials: A
authors.lastname: Plasencia Amela
authors.forename: Jesús María
authors.initials: JM
authors.lastname: Fernández Gómez
authors.forename: Maite
authors.initials: M
authors.lastname: Fernández García
authors.forename: Oscar
authors.initials: O
authors.lastname: Rodríguez Faba
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Regadera Sejas
mesh_terms: D000328:Adult; D001706:Biopsy; D006801:Humans; D007621:Karyotyping; D008297:Male; D009845:Oligospermia / Q000209:etiology* / Q000473:pathology; D012708:Sertoli Cells; D013577:Syndrome; D013737:Testis / Q000473:pathology