title: [Electron microscopy study regarding the etiology and the pathogenesis of acne vulgaris].
abstract: The etiology and the pathogenesis of acne vulgaris are not complete cleared up yet. This work presents the results of the electronomicroscopic examinations effected on lesions of acne vulgaris biopsied from 5 patients with different clinical forms of disease (including acne fulminans). In this study we had in view the investigation and description of the ultrastructural modifications that followed the intervention of the 4 factors incriminated in the etiology and pathogenesis of acne: sebaceous hypersecretion, hyperkeratosis pilosebaceous infundibulum, bacterial colonisation, perifollicular inflammation. The ultrastructural aspects that we had in view underline the role of the 4 etiology and pathogenesis factors of acne vulgaris, confirming the data related by the specialised literature.
authors.affiliation: Clinica Dermatologică, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
authors.forename: Daciana
authors.initials: D
authors.lastname: Brănişteanu
authors.forename: Zenaida
authors.initials: Z
authors.lastname: Petrescu
authors.forename: Carmen Elena
authors.initials: CE
authors.lastname: Cotrutz
authors.forename: C
authors.initials: C
authors.lastname: Cotrutz
authors.forename: Gioconda
authors.initials: G
authors.lastname: Dobrescu
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D001706:Biopsy; D005260:Female; D018859:Hair Follicle / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron / Q000379:methods; D012627:Sebaceous Glands / Q000648:ultrastructure*; D012867:Skin / Q000473:pathology