title: Comparison of the predictive value of exercise-induced ST depression versus exercise technetium-99m sestamibi single-photon emission computed tomographic imaging for detection of coronary artery disease in patients with left ventricular hypertrophy.
abstract: Scant knowledge exists regarding the significance of either additional ST depression in the presence of baseline depression or new stress-induced ST depression in patients with left ventricular (LV) hypertrophy. Accordingly, the purpose of this investigation is to determine whether the appearance and/or severity of ST abnormalities during exercise stress testing can accurately predict the prevalence of ischemic burden as measured by quantitative technetium-99m-sestamibi single-photon emission computed tomographic imaging in patients with LV hypertrophy. The results show that the presence of exercise ST-segment depression, as well as its magnitude, are not accurate predictors for identifying patients with coronary artery disease in the presence of electrocardiographic criteria for LV hypertrophy.
authors.affiliation: Penn State Hershey Medical Center, Hershey, Pennsylvania, USA.
authors.forename: Dharmesh
authors.initials: D
authors.lastname: Patel
authors.forename: Timir S
authors.initials: TS
authors.lastname: Baman
authors.forename: George A
authors.initials: GA
authors.lastname: Beller
mesh_terms: D000328:Adult; D000368:Aged; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D012720:Severity of Illness Index; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi