[Primary urothelial carcinoma of the bulbomembranous urethra. Histologic and immunohistochemical study of a case].
OBJECTIVE
We report a case of a primary urothelial carcinoma of the bulbomembranous urethra, with special emphasis on histopathological and immunohistochemical findings.


RESULTS
A 63-year-old man presented urethral obstruction symptoms. A radical phalectomy was performed and a 4.5 x 4 cm bulbomembranous urethral tumor was observed. Histopathological analysis disclosed an urothelial carcinoma, that showed positive immunostaining for cytokeratin AE1/AE3, cytokeratin 7, carcinoembrionic antigen and epithelial membrane antigen. The patient received radiotherapy and adjuvant chemotherapy and is currently free of disease.


CONCLUSIONS
Posterior male urothelial carcinoma of the urethra is a rare neoplasm that usually is mistaken clinically for a benign lesion. The diagnostic is generally made in advanced stages with a poor therapeutical response.
Parada
David
D
Servicio de Anatomía Patológica, Hospital Vargas de Caracas, Caracas, Venezuela. parada@cantv.net
Páez
Alberto
A
Acosta
Marisela
M
Caricote
Luis
L
Trujillo
Eduardo
E
Luigi
Juan Carlos
JC
Farías
Rosa M
RM
D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014523:Urethral Neoplasms / Q000473:pathology*