title: Improved accuracy of noninvasive electron beam coronary angiography.
abstract: OBJECTIVE
  We investigated the effect of electrocardiographic (ECG) triggering on the accuracy of coronary electron-beam angiography (EBA) as compared with invasive angiography.
  
  
  METHODS
  One hundred thirty-three patients with suspected coronary disease were studied with intravenous coronary EBA and conventional coronary angiography. Patients were divided into 2 groups based upon ECG triggering on the EBA study. Patients were divided into 2 groups based upon different ECG triggering used: 80% R-R interval trigger method (group 1, n = 53) and end-systolic triggering (group 2, n = 80). End-systolic ECG triggering, which started at the end of the T wave in each study, was based on baseline heart rate.
  
  
  RESULTS
  Overall sensitivity to detect a > or = 50% luminal stenosis was 69% in group 1 and 91% in group 2 (P = 0.002); specificity was 82% and 94% in group 1 and group 2, respectively (P < 0.001). Using newer triggering techniques (group 2) with EBA, the sensitivity, specificity, and accuracy for patients with disease of the left main coronary artery or 3 vessel disease was 100%, 94%, and 98%, respectively. Nonassessability of coronary segments on 3D-EBA images was reduced from 35% in group 1 to 9% in group 2 patients (P < 0.001). The number of motion-free coronary images increased from 67% to 95% from group 1 to group 2 (P < 0.0001).
  
  
  CONCLUSIONS
  End-systolic ECG triggering improves accuracy, image quality, and assessability of segments of coronary EBA for the detection of angiographic coronary artery disease.
authors.affiliation: Department of Radiology, Cardiovascular Institute and FuWai Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, 100037, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Lu
authors.forename: David M
authors.initials: DM
authors.lastname: Shavelle
authors.forename: Songshou
authors.initials: S
authors.lastname: Mao
authors.forename: Lynn
authors.initials: L
authors.lastname: Chen
authors.forename: Janis
authors.initials: J
authors.lastname: Child
authors.forename: Sivi
authors.initials: S
authors.lastname: Carson
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Budoff
mesh_terms: D000465:Algorithms; D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000175:diagnosis*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed