title: 'State of the art' of radical hysterectomy; current practice in European oncology centres.
abstract: Quality control of medical performance requires adequate 'state-of-the-art' data and this is currently not uniformly defined for radical hysterectomy. We have used data from a randomised multicentre clinical trial examining the clinical significance of surgical drains following radical hysterectomy (European Organisation for Research and Treatment of Cancer (EORTC)-55962). Although the study was not designed to analyse the quality of the surgical procedure per se, surgical data during and after the operation were carefully noted. A total of 234 patients from 12 European institutes were included in the study. We reported on the clinical and surgical characteristics, the radicality of surgery and short- and long-term complications of radical hysterectomy: median duration of surgery: 240 min; median number of nodes removed: 26; lymph node metastases: 22%; post-operative mortality: <1%; urinary tract infection: 42%; deep venous thrombosis: 3%; fistula: 2%. The data from our study provides an honest and realistic picture of the current practice of radical hysterectomy among European oncology centres and may be considered as the 'standard of care' in this part of the world.
authors.affiliation: Department of Gynecology, Leiden University Medical Centre, The Netherlands. j.b.m.z.trimbos@lumc.nl
authors.forename: J B
authors.initials: JB
authors.lastname: Trimbos
authors.forename: M
authors.initials: M
authors.lastname: Franchi
authors.forename: F
authors.initials: F
authors.lastname: Zanaboni
authors.forename: J v d
authors.initials: Jv
authors.lastname: Velden
authors.forename: I
authors.initials: I
authors.lastname: Vergote
mesh_terms: D002173:Cancer Care Facilities; D016889:Endometrial Neoplasms / Q000601:surgery*; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D011364:Professional Practice; D011786:Quality Control; D002583:Uterine Cervical Neoplasms / Q000601:surgery*; D014625:Vaginal Neoplasms / Q000601:surgery*