title: Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: a general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group.
abstract: The Pd(0)-mediated rapid coupling (trapping) reaction of methyl iodide with an excess amount of alkynyltributylstannane has been developed with the aim to incorporate a short-lived (11)C-labeled methyl group into biologically active organic compounds with a 1-propynyl structural unit.
authors.affiliation: Division of Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Hosoya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Wakao
authors.forename: Yurie
authors.initials: Y
authors.lastname: Kondo
authors.forename: Hisashi
authors.initials: H
authors.lastname: Doi
authors.forename: Masaaki
authors.initials: M
authors.lastname: Suzuki