title: [Epidemiologic and clinical aspects of acute hepatitis B in the past decade].
abstract: To study the clinical and epidemiological aspects of acute B hepatitis during the last 11 years. We retrospectively studied 1712 patient files, admitted in the Department of Infectious Diseases Iaşi, with acute B hepatitis between 1992-2002. The majority of the patients (69%) had an urban origin. Teenagers and young adults were predominantly affected (59% had between 15 and 34 years). A point of entry of the pathogen was identified only in 20% of the patients. The mean incubation period was 4 month. 24% of the patients had a prolonged form of the disease (over 30 days of jaundice). A fulminant evolution was noted in 1.2% of cases. Extrahepatic involvement was described in 25% of the patients. The global mortality was 1.15%. The number of patients with acute B hepatitis decreased by half during the last 11 years.
authors.affiliation: Facultatea de Medicină, Clinica de Boli infecţioase, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
authors.forename: Doina
authors.initials: D
authors.lastname: Mihalache
authors.forename: Andrei
authors.initials: A
authors.lastname: Vâţă
authors.forename: Alla
authors.initials: A
authors.lastname: Vâţă
authors.forename: Carmen
authors.initials: C
authors.lastname: Corcaci
authors.forename: M
authors.initials: M
authors.lastname: Hurmuzache
authors.forename: Roxana
authors.initials: R
authors.lastname: Scurtu
mesh_terms: D000293:Adolescent; D000328:Adult; D006509:Hepatitis B / Q000453:epidemiology* / Q000401:mortality; D006801:Humans; D015994:Incidence; D008499:Medical Records; D015995:Prevalence; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D015996:Survival Rate