title: Numerical simulation of a systemic flow test rig.
abstract: In this study, numerical simulation was carried out to investigate the dynamic response of a systemic flow test rig that is widely used for in vitro study of prosthesis in the cardiovascular system. In the system the physiological impedance of systemic circulation was modeled as a resistance-capacitance-resistance type. The system analysis was directly based on differential equations describing the system dynamics, and numerically solved using the fourth-order Runge-Kutta method. Results showed that pressure in the systemic circulation test rig could be successfully simulated with the developed model. From the numerical experiment, it was found that the maximum stroke of the driving mechanism, the flow coefficients and opening of the control valves, and the initial volume of air in the compliance strongly affect the dynamic performance of the test rig. The numerical method developed is a useful tool in the design and optimization of the system configuration.
authors.affiliation: School of Mechanical and Production Engineering, Nanyang Technological University, Singapore.
authors.forename: Yubing
authors.initials: Y
authors.lastname: Shi
authors.forename: Tony J H
authors.initials: TJ
authors.lastname: Yeo
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D002320:Cardiovascular Physiological Phenomena; D006350:Heart Valve Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D011474:Prosthesis Design; D011673:Pulsatile Flow