title: Rapid accumulation of eosinophils in lung lesions in guinea pigs infected with Mycobacterium tuberculosis.
abstract: Guinea pig eosinophils were positively identified in bronchoalveolar lavage populations and in the lung granulomas of Mycobacterium tuberculosis-infected guinea pigs. It is possible that the rapid influx of these cells, and their subsequent degranulation during acute pulmonary tuberculosis, may play a key role in the susceptibility of this animal model.
authors.affiliation: Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA. Todd.Lasco@colostate.edu
authors.forename: Todd M
authors.initials: TM
authors.lastname: Lasco
authors.forename: Oliver C
authors.initials: OC
authors.lastname: Turner
authors.forename: Lynne
authors.initials: L
authors.lastname: Cassone
authors.forename: Isamu
authors.initials: I
authors.lastname: Sugawara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamada
authors.forename: David N
authors.initials: DN
authors.lastname: McMurray
authors.forename: Ian M
authors.initials: IM
authors.lastname: Orme
mesh_terms: D000818:Animals; D004198:Disease Susceptibility; D004804:Eosinophils / Q000502:physiology*; D006168:Guinea Pigs; D008168:Lung / Q000473:pathology*; D014397:Tuberculosis, Pulmonary / Q000276:immunology / Q000473:pathology*