title: The ABCs of psychopharmacology.
abstract: The forgoing represents an attempt to reduce psychopharmacology to a presynaptic neuron-synapse-post-synaptic neuron event. Obviously other strategies might be employed resulting in equal or perhaps greater clarity. Limitations of this approach include the lack of discussion about neuronal modulation, second messenger systems (which most NTs discussed here use), expansion of the ion channel discussion, and the implications of excitatory vs. inhibitory physiological effects. Nonetheless, we find this template for understanding psychotropic drug mechanism of action a fruitful lens through which to guide further study of these drugs. We feel like we are moving toward a silver dollar-size circle.
authors.affiliation: University of Alabama School of Nursing, Birmingham, AL, USA. KELTNER@son.uab.edu
authors.forename: Norman L
authors.initials: NL
authors.lastname: Keltner
authors.forename: Frances J
authors.initials: FJ
authors.lastname: Kelley
mesh_terms: D001665:Binding Sites / Q000502:physiology; D001921:Brain / Q000187:drug effects* / Q000378:metabolism*; D006801:Humans; D007473:Ion Channels / Q000187:drug effects* / Q000378:metabolism*; D001523:Mental Disorders / Q000188:drug therapy* / Q000378:metabolism*; D011600:Psychopharmacology; D011619:Psychotropic Drugs / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use*
chemical_list: D007473:Ion Channels; D011619:Psychotropic Drugs