[Pancreatic insulinomas: diagnosis and treatment].
BACKGROUND
Despite its rarity, the insulinoma is the most common pancreatic neuroendocrine tumor.


OBJECTIVE
Analyze clinical and immunohistochemical data from surgical resection of the pancreas insulinoma.


METHODS
Twelve cases are described, concerning surgical aspects, complications and medium-long term outcome of patients. They underwent surgical treatment due to clinical suspicion and biochemical diagnosis of hypoglycemia and hyperinsulinism.


RESULTS
The insulinoma was identified preoperatively in seven patients, while intraoperative ultrasonography and palpation were necessary for diagnosis in the other cases. Eight patients underwent pancreatic resection and pancreatic leak was observed in seven cases. Two patients developed diabetes mellitus and no mortality occurred in the current series.


CONCLUSIONS
All patients presented satisfactory outcome and remained asymptomatic with normal glicemia levels.
Apodaca-Torrez
Franz Robert
FR
Disciplina de Grastroenterologia Cirúrgica do Departamento de Cirurgia da Universitade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brasil. apodaca@uol.com.br
Triviño
Tarcisio
T
Lobo
Edson José
EJ
Goldenberg
Alberto
A
Figueira
Antônio
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007340:Insulinoma / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010185:Pancreatic Fistula / Q000209:etiology; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery*
D001786:Blood Glucose