title: Survival curve modified through dietary restriction (DR) in male Donryu rats.
abstract: It is well known that dietary restriction (DR) can prolong the life of certain inbred strains of laboratory rodents. This prolongation can be usually shown in a survival curve in parallel to that of non-DR groups. On an outbred strain, Donryu, however, DR resulted in a unique pattern of survival curve. In DR group, the first three quarters of male rats survived longer in a form parallel to non-DR, while the last quarter of them survived far longer in a quite different shape from controlled group. DR may select animals that are capable of longer survival within Donryu. The selection of a quarter animal indicates the parameter for selection may be regulated by a single recessive locus.
authors.affiliation: Laboratory Animal Research Facilities, National Institute for Longevity Sciences, 36-3, Gengo Morioka-cho, Obu 474-8522, Japan. sitanaka@nils.go.jp
authors.forename: Shin
authors.initials: S
authors.lastname: Tanaka
authors.forename: Tamio
authors.initials: T
authors.lastname: Ohno
authors.forename: Osamu
authors.initials: O
authors.lastname: Miyaishi
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Itoh