QSAR studies on psychotomimetic phenylalkylamines.
Quantitative Structure-Activity Relationship (QSAR) studies on a series of psychotomimetic phenylalkylamines have been made using a combination of Minimum Topological Difference (MTD) method and topological methodology. The topological indices used being a pool of distance-based topological indices. The regression analyses have shown that excellent results are obtained in multiparametric model containing MTD parameters, topological indices in that quantum chemical parameters has to be introduced. The predictive power of the proposed model is discussed on the basis of cross-validation parameters.
Thakur
Mamta
M
Department of Chemistry, Softvision Institute of Biotechnology, Indore, India.
Thakur
Abhilash
A
Khadikar
Padmakar V
PV
D000814:Aniline Compounds / Q000737:chemistry* / Q000494:pharmacology*; D006213:Hallucinogens / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D021281:Quantitative Structure-Activity Relationship
D000814:Aniline Compounds; D006213:Hallucinogens