title: Leishmanial infection: analysis of its first steps. A review.
abstract: The first steps in leishmaniasis are critical in determining the evolution of the disease. Major advances have recently been done in understanding this crucial moment. Fundamental research in parasite-vector interaction, parasite biology, insect saliva, and vertebrate host response have shed new light and uncovered a most fascinating and complex moment in leishmaniasis. We review here some of these aspects and we try to connect them in a logical framework.
authors.affiliation: Departamento de Patologia e Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília, DF, 70910-900, Brasil. marcalmo@unb.br
authors.forename: M C
authors.initials: MC
authors.lastname: de Almeida
authors.forename: V
authors.initials: V
authors.lastname: Vilhena
authors.forename: A
authors.initials: A
authors.lastname: Barral
authors.forename: M
authors.initials: M
authors.lastname: Barral-Netto
mesh_terms: D000818:Animals; D006790:Host-Parasite Interactions; D006801:Humans; D007111:Immunity, Cellular; D007299:Insect Bites and Stings / Q000276:immunology; D007303:Insect Vectors / Q000502:physiology*; D007891:Leishmania / Q000502:physiology*; D007896:Leishmaniasis / Q000276:immunology / Q000469:parasitology / Q000635:transmission; D051379:Mice; D023421:Models, Animal; D011576:Psychodidae / Q000502:physiology*