Silicone rubber: an alternative for repair of articular cartilage defects.
Silicone-rubber implants were used to fill full-thickness articular cartilage in the trochlea area of the knee joint in rabbits, for the purpose of studying the long-term influence of silicone-rubber implant on surrounding articular cartilage. Forty eight weeks after surgery, the silicone rubbers were still fitted tightly into the defects; surrounding cartilage showed mild degeneration, better than the control group. Our results showed silicone-rubber implantation for repairing local articular cartilage defects can effectively delay the pathogenetic progression of osteoarthritis.
Wang
Mei
M
Institute of Sports Medicine, Third Hospital, Peking University, No. 49, North Garden Road, Haidian District, 100083, Beijing, P.R. China. yuchangl@public3.bta.net.cn
Yu
Changlong
C
D000818:Animals; D002358:Cartilage, Articular / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery*; D011817:Rabbits; D012826:Silicone Elastomers / Q000627:therapeutic use*; D014945:Wound Healing / Q000502:physiology
D012826:Silicone Elastomers