title: Sentinel node biopsy for breast cancer: is it already a standard of care? A survey of current practice in an Italian region.
abstract: BACKGROUND
  Although sentinel node biopsy (SNB) is becoming the standard approach for axillary staging in patients with small breast cancer, criteria for patient selection and some technical aspects of the procedure have yet to be clearly defined. The aim of the present survey was therefore to investigate the way in which SNB is used by general surgeons working in the Veneto region, Italy.
  
  
  METHODS
  A 29-item questionnaire regarding various aspects of SNB practice was mailed to surgeons in charge of breast surgery in all the 56 surgical centres of the region.
  
  
  RESULTS
  The rate of response to the questionnaire was 82.1% (n = 46); 69.6% (n = 32) of the respondents routinely perform SNB in their clinical practice. Most of the interviewed surgeons (93.5%) expressed the belief that the acceptable false negative rate should be < or =5%. However, among the surgeons who perform SNB, only 34.4% performed more than 20 SNB during the learning phase. Indications are limited to tumours of < or =1 cm by 31.2% (n = 10) of respondents, < or =2 cm by 46.9% (n = 15) and < or =3 cm by 21.9% (n = 7). Almost all respondents (93.7%) agreed that a clinically positive axilla is a contraindication to SNB, while opinions differed widely concerning other potential contraindications. In most of the centres considered, SN identification is undertaken on the day before surgery using a subdermal injection of 30-50 MBq of 99mTc-albumin-nanocolloid followed by lymphoscintigraphy.
  
  
  CONCLUSIONS
  SNB is currently performed in the majority of hospitals in the Veneto region. However, the training phase and criteria used for patient selection differ from centre to centre. Certified training courses and shared guidelines are therefore highly desirable.
authors.affiliation: University of Padova, Istituto di Clinica Chirurgica II, Padova (35128), Italy. giorgio.zavagno@unipd.it
authors.forename: Giorgio
authors.initials: G
authors.lastname: Zavagno
authors.forename: Gian Luca
authors.initials: GL
authors.lastname: De Salvo
authors.forename: Dario
authors.initials: D
authors.lastname: Casara
authors.forename: Paola
authors.initials: P
authors.lastname: Del Bianco
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Meggiolaro
authors.forename: Carlo Riccardo
authors.initials: CR
authors.lastname: Rossi
authors.forename: Mariaelena
authors.initials: M
authors.lastname: Pierobon
authors.forename: Mario
authors.initials: M
authors.lastname: Lise
mesh_terms: D001291:Attitude of Health Personnel; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology*; D002983:Clinical Competence; D005188:False Negative Reactions; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D007558:Italy; D007858:Learning; D008197:Lymph Node Excision / Q000706:statistics & numerical data; D021701:Sentinel Lymph Node Biopsy / Q000592:standards / Q000706:statistics & numerical data*