A novel chiral terpyridine macrocycle as a fluorescent sensor for enantioselective recognition of amino acid derivatives.
Terpyridine macrocycle 1 is shown to be a strong chelating agent for organic ammonium salts and also a useful chromophore in fluorescent sensing. It exhibits very good enantioselectivity (K(obs)(S)/K(obs)(R)= 3.8) in chiral discrimination of alpha-phenylglycine methyl ester hydrochloride (PhEtOMe).
Wong
Wing-Leung
WL
Department of Biology and Chemistry, Open Laboratory of Chirotechnology, Institute of Molecular Technology for Drugs Discovery and Synthesis, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong SAR, China.
Huang
Ka-Hung
KH
Teng
Pang-Fei
PF
Lee
Chi-Sing
CS
Kwong
Hoi-Lun
HL
D000596:Amino Acids / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
D000596:Amino Acids; D005456:Fluorescent Dyes; D047028:Macrocyclic Compounds; D011725:Pyridines