title: Early results of transcutaneous injection laryngoplasty with micronized acellular dermis versus type-I thyroplasty for glottic incompetence dysphonia due to unilateral vocal fold paralysis.
abstract: Medialization thyroplasty (type I) has become the gold standard to improve glottic closure due to unilateral vocal fold paralysis. A newer injection method utilizing homologous collagen from cadaveric human tissue has been described as an attractive alternative as no donor site is required, there is a very low risk of hypersensitivity, and the intact, acellular collagen fibers may suffer a reduced long-term reabsorption rate. Preliminary results on eight patients comparing presurgical and postsurgical parameters (perceptual, stroboscopic, acoustic, and aerodynamic) revealed comparable results when compared with a control group of individuals, age- and sex-matched, that had undergone standard medialization thyroplasty (type I). Further study is needed to assess the long-term results with this minimally invasive method of vocal fold medialization.
authors.affiliation: University of Miami School of Medicine, The Department of Otolaryngology, Miami, Florida 33101, USA. dlundy@med.miami.edu
authors.forename: Donna S
authors.initials: DS
authors.lastname: Lundy
authors.forename: Roy R
authors.initials: RR
authors.lastname: Casiano
authors.forename: Mark E
authors.initials: ME
authors.lastname: McClinton
authors.forename: Jun W
authors.initials: JW
authors.lastname: Xue
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials / Q000008:administration & dosage; D016022:Case-Control Studies; D003094:Collagen / Q000008:administration & dosage*; D005260:Female; D005931:Glottis / Q000503:physiopathology*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures; D013061:Speech Acoustics; D013068:Speech Production Measurement; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000150:complications / Q000601:surgery*; D014827:Vocal Cords / Q000601:surgery*; D014832:Voice Disorders / Q000209:etiology / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials; D003094:Collagen