title: After the holy grail: establishing a molecular basis for Mammalian olfaction.
abstract: The quest to identify mammalian odorant receptors was a triumph of molecular biology. The characterization of these molecules has provided extraordinary insight into the strategy used by one neuronal system to organize sensory structures and code complex information. The odorant receptor genes have also served as powerful tools in understanding genomic organization and gene regulation.
authors.affiliation: Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, USA. rreed@jhmi.edu
authors.forename: Randall R
authors.initials: RR
authors.lastname: Reed
mesh_terms: D000818:Animals; D016678:Genome; D006801:Humans; D008024:Ligands; D008954:Models, Biological; D009812:Odorants; D009833:Olfactory Pathways / Q000502:physiology*; D011485:Protein Binding; D018035:Receptors, Odorant / Q000235:genetics; D012903:Smell / Q000502:physiology*
chemical_list: D008024:Ligands; D018035:Receptors, Odorant