title: Fragmentation of amidinated peptide ions.
abstract: The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be enhanced. The additional information conveyed by the observed fragment ions should facilitate protein identifications.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington, Indiana 47401, USA.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Beardsley
authors.forename: James P
authors.initials: JP
authors.lastname: Reilly
mesh_terms: D000577:Amides / Q000737:chemistry*; D000595:Amino Acid Sequence; D007477:Ions / Q000737:chemistry; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010446:Peptide Fragments / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D000577:Amides; D007477:Ions; D010446:Peptide Fragments; D010455:Peptides