Excess electron-transfer-based repair of a Cis-Syn thymine dimer in DNA is not sequence dependent.
The repair of a cis-syn pyrimidine dimer by single electron reduction is possible in DNA over large distances. The intervening base sequence does not influence the repair yield.
Breeger
Sascha
S
Department of Chemistry, Philipps-University Marburg, Hans-Meerwein Strasse, D-35032 Marburg, Germany.
Hennecke
Ulrich
U
Carell
Thomas
T
D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000528:radiation effects; D004249:DNA Damage; D004260:DNA Repair; D004583:Electrons; D005415:Flavins / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D009690:Nucleic Acid Conformation; D010777:Photochemistry; D011740:Pyrimidine Dimers / Q000737:chemistry* / Q000378:metabolism; D013329:Structure-Activity Relationship
D005415:Flavins; D011740:Pyrimidine Dimers; D004247:DNA