Antimicrobial activity of Hyptis ovalifolia towards dermatophytes.
The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of   500  g/ml.
Souza
Lúcia K H
LK
Laboratório de Micologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, GO, Brasil. lucki@persogo.com.br
de Oliveira
Cecília M A
CM
Ferri
Pedro H
PH
de Oliveira Júnior
Juldásio Galdino
JG
de Souza Júnior
Ary Henrique
AH
Fernandes
Orionalda de Fátima Lisboa
Ode F
Silva
Maria do Rosário R
Mdo R
D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000145:classification / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D031331:Hyptis; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology
D000935:Antifungal Agents; D010936:Plant Extracts