title: [Type I sensitization to seminal fluid. Urticaria and angioedema].
abstract: Allergy to human seminal fluid is a rare but potentially life-threatening disorder. Acute symptoms range from local reactions to generalized symptoms. A 30-year-old woman experienced vulvovaginal itching, erythema and swelling as well as generalized urticaria and angioedema of the neck and face after unprotected sexual intercourse. A scratch test with undiluted seminal fluid and the detection of specific IgE antibodies revealed a type I allergy to seminal fluid. Risk factors and therapeutic options are discussed.
authors.affiliation: Klinik für Dermatologie und Allergologie, Universitätsklinikum der RWTH Aachen, Aachen.
authors.forename: C
authors.initials: C
authors.lastname: Bangard
authors.forename: I
authors.initials: I
authors.lastname: Rösener
authors.forename: H F
authors.initials: HF
authors.lastname: Merk
authors.forename: J M
authors.initials: JM
authors.lastname: Baron
mesh_terms: D000328:Adult; D000799:Angioedema / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis* / Q000276:immunology; D007428:Intradermal Tests; D012661:Semen / Q000276:immunology*; D014581:Urticaria / Q000175:diagnosis* / Q000276:immunology; D014627:Vaginitis / Q000175:diagnosis* / Q000276:immunology