title: Enophthalmos as initial manifestation of occult, mammogram-negative carcinoma of the breast.
abstract: A patient with enophthalmos was found to have occult metastatic breast carcinoma to the orbit despite normal findings on breast examination and mammogram. Enophthalmos can be a sign of serious systemic disease and should be appropriately investigated. Despite radiologically interpreted normal orbital and breast imaging, the clinician should rule out underlying subclinical malignancy and consider orbital biopsy.
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Gary A
authors.initials: GA
authors.lastname: Stopyra
authors.forename: Brian P
authors.initials: BP
authors.lastname: Marr
authors.forename: Mark L
authors.initials: ML
authors.lastname: Moster
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000628:therapy; D018275:Carcinoma, Lobular / Q000737:chemistry / Q000175:diagnosis* / Q000628:therapy; D003131:Combined Modality Therapy; D015841:Enophthalmos / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography
chemical_list: D014408:Biomarkers, Tumor