Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomography.
We present an algorithm to reconstruct chromosphere concentration images directly rather than following the traditional two-step process of reconstructing wavelength-dependent absorption coefficient images and then calculating chromosphere concentration images. This procedure imposes prior spectral information into the image reconstruction that results in a dramatic improvement in the image contrast-to-noise ratio of better than 100%. We demonstrate this improvement with simulations and a dynamic blood phantom experiment.
Li
Ang
A
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA. angli@nmr.mgh.harvard.edu
Zhang
Quan
Q
Culver
Joseph P
JP
Miller
Eric L
EL
Boas
David A
DA
D000465:Algorithms; D000818:Animals; D016477:Artifacts; D004058:Diffusion; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009994:Osmolar Concentration; D010108:Oxyhemoglobins / Q000378:metabolism; D041622:Tomography, Optical
D006454:Hemoglobins; D010108:Oxyhemoglobins; C100003:deoxyhemoglobin