[Lung and heart-lung transplantation in Rabin medical center: early experience with 70 cases].
Lung transplantation is a relatively new field in solid organ transplantation. We present our early experience with the first 70 cases at the Rabin Medical Center during the years 1997-2003. Forty seven patients underwent single lung, eight double lung and eight heart-lung transplantations. The patients treated included 49 men and 21 women aged 5-66 years. There were 26 cases with emphysema COPD. 30 patients with pulmonary fibrosis. 5 patients with pulmonary hypertension/Eisenmenger and 9 patients with cystic fibrosis and bronchiectasis. Although early results (1997-1999) showed 1 and 3 year survival of only 50%, in the last 3 years (2000-2003), survival reached 84% and 82% at 1 and 3 years respectively. Improvement in the success rate is due to better patient selection, new immunosuppressive regimen and, most importantly, excellent teamwork. We conclude that lung transplantation is a viable option for selected patients with end-stage lung disease.
Kramer
Mordechai R
MR
Pulmonary Institute, Cardiothoracic Surgery and Anesthesiology Departments, Rabin Medical Center.
Saute
Milton
M
Eidelman
Leonid
L
Aravot
Dan
D
Fink
Gershon
G
Shitrit
David
D
Izbicky
Gabriel
G
Izvicky
Gavriel
G
Dayan
Daniel Ben
DB
Bakal
Ilana
I
Kogan
Alex
A
Gendel
Boris
B
Vidne
Bernardo
B
Sahar
Gideon
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D016041:Heart-Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D006801:Humans; D007557:Israel; D008171:Lung Diseases / Q000145:classification / Q000601:surgery; D016040:Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors