title: Erythrodermic chronic actinic dermatitis responding only to topical tacrolimus.
abstract: Chronic actinic dermatitis (CAD) is a disorder characterized by an often severe persistent eczematous eruption induced by exposure to ultraviolet radiation. Treatment involves photoprotective measures and topical corticosteroid therapy and in more severe cases, systemic immunosuppression. Occasionally, however, the condition can prove very resistant to all therapy and be severely disabling. We report a patient with CAD who resisted standard topical and systemic treatments, but responded to topical tacrolimus ointment 0.1% (Protopic).
authors.affiliation: Department of Photobiology, St. John's Institute of Dermatology, St. Thomas' Hospital, London SE1 7EH, UK.
authors.forename: A V
authors.initials: AV
authors.lastname: Evans
authors.forename: R A
authors.initials: RA
authors.lastname: Palmer
authors.forename: J L M
authors.initials: JL
authors.lastname: Hawk
mesh_terms: D000287:Administration, Topical; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010787:Photosensitivity Disorders / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology; D016559:Tacrolimus / Q000008:administration & dosage*
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus