A novel approach to 2-arylated quinolines: electrocyclization of alkynyl imines via vinylidene complexes.
[reaction: see text] Alkynyl imines underwent [4 + 2] electrocyclization in the presence of 20 mol % W(CO)(5)(THF) to give 2-arylated quinolines in good yields. A deuterium labeling study suggests that the reaction proceeds via a tungsten vinylidene complex.
Sangu
Kenichiro
K
Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro Toshima-ku, Tokyo 171-8588, Japan.
Fuchibe
Kohei
K
Akiyama
Takahiko
T