Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy.
Veldhorst-Janssen
N M L
NM
Boersma
H H
HH
de Krom
M C T F M
MC
van Rijswijk
R E N
RE
D000284:Administration, Oral; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology* / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy; D004347:Drug Interactions; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D002955:Leucovorin / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000188:drug therapy; D005641:Tegafur / Q000494:pharmacology* / Q000627:therapeutic use
D000927:Anticonvulsants; D000964:Antimetabolites, Antineoplastic; D005641:Tegafur; D010672:Phenytoin; D002955:Leucovorin