title: Sclerosing lipogranuloma of the nose: a new treatment using adipose tissue transplantation.
abstract: We report a series of 45 patients visiting our clinic with distorted contour of the nose after having their noses augmented with injectable substances. The most common clinical presentation was a palpable mass on the dorsum of the nose, erythema with or without telangiectasia on the overlying skin, and nodularity of the nose. The onset of symptoms varied from 1 to 16 years after injection. They were treated by surgical excision, but this was always followed by a saddle-nose deformity. To correct this defect, we propose a new technique of adipose tissue transplantation that yields satisfactory results. Pathological reports of the excised mass showed a foreign body granuloma known as a sclerosing lipogranuloma (paraffinoma or siliconoma).
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
authors.forename: Choladhis
authors.initials: C
authors.lastname: Sinrachtanant
authors.forename: Weerachai
authors.initials: W
authors.lastname: Tantinikorn
authors.forename: Malee
authors.initials: M
authors.lastname: Warnnissorn
authors.forename: Paraya
authors.initials: P
authors.lastname: Assanasen
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D001672:Biocompatible Materials / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D015745:Granuloma, Foreign-Body / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000601:surgery; D009667:Nose Deformities, Acquired / Q000601:surgery; D009668:Nose Diseases / Q000601:surgery*; D017060:Patient Satisfaction; D012189:Retrospective Studies; D012225:Rhinoplasty / Q000009:adverse effects
chemical_list: D001672:Biocompatible Materials