Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion.
The channel-forming diglycolylated heptapeptides containing the amino acid sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly have been found to complex chloride in CDCl(3). The strength of the interaction depends on the terminal alkyl groups and on chloride's countercation.
Pajewski
Robert
R
Department of Molecular Biology & Pharmacology, Washington University School of Medicine, Campus Box 8103, 660 S. Euclid Ave., St. Louis, MO 63110, USA.
Ferdani
Riccardo
R
Schlesinger
Paul H
PH
Gokel
George W
GW
D000595:Amino Acid Sequence; D002712:Chlorides / Q000737:chemistry*; D002725:Chloroform / Q000737:chemistry; D003903:Deuterium; D005998:Glycine / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry*; D010446:Peptide Fragments / Q000032:analysis; D011392:Proline / Q000737:chemistry; D011485:Protein Binding
D002712:Chlorides; D009842:Oligopeptides; D010446:Peptide Fragments; D002725:Chloroform; D011392:Proline; D003903:Deuterium; D005998:Glycine