[Invasive hydatiform mole in a postmenopausal woman].
Gestational trophoblastic disease occurs rarely in postmenopausal women. We report the case of a 51 year-old postmenopausal woman with an invasive complete mole. Invasive mole should be distinguished from choriocarcinoma, by a thorough sampling showing infiltrative molar villi associated with a prominent trophoblastic proliferation. Gestational trophoblastic diseases in postmenopausal women can represent malignant changes of trophoblastic remnants of a prior pregnancy after a period of latency or correspond to a possible current pregnancy as demonstrated by an ovarian corpus luteum of pregnancy in our patient. The unusual finding in our case is that the gestational trophoblastic disease follows a pregnancy occurring after a biologically confirmed menopause.
de  la Fouchardière
Arnaud
A
Service d'anatomie et cytologie pathologiques, Hôpital de la Croix Rousse, Lyon.
Cassignol
Alexandre
A
Benkiran
Leila
L
Rudigoz
René Charles
RC
Gougeon
Alain
A
Devouassoux-Shisheboran
Mojgan
M
D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000473:pathology* / Q000601:surgery; D007044:Hysterectomy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery; D017698:Postmenopause; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery