title: Thyroxine-induced hypermotor seizure.
abstract: Thyroxine-induced epilepsy is a very rare condition occurring in epileptic patients. Here we report a boy with thyroxine-induced hypermotor seizure (HMS) following thyroxine administration for his central hypothyroidism secondary to surgery and cranial radiation for his brain tumor. After 3 years seizure-free period, he had repeated HMS, seven to eight attacks per day, after initiation L-thyroxine treatment. Following reduction of the daily thyroxine dose, his seizures decreased in frequency. To our knowledge, this is the first reported case of HMS associated with L-thyroxine administration.
authors.affiliation: Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, Izmir, 35530 Karşiyaka, Turkey. adem.aydin@deu.edu.tr
authors.forename: Adem
authors.initials: A
authors.lastname: Aydin
authors.forename: A Pinar
authors.initials: AP
authors.lastname: Cemeroglu
authors.forename: Baris
authors.initials: B
authors.lastname: Baklan
mesh_terms: D002648:Child; D004569:Electroencephalography; D006801:Humans; D006948:Hyperkinesis / Q000139:chemically induced* / Q000150:complications; D007037:Hypothyroidism / Q000188:drug therapy; D008297:Male; D012640:Seizures / Q000139:chemically induced* / Q000503:physiopathology; D013974:Thyroxine / Q000009:adverse effects*
chemical_list: D013974:Thyroxine