[Diagnostic evaluation of fiberopticbronchoscopy in bronchogenic carcinoma in neoplasic-suspicious cases].
Fiberopticbronchoscopy (FOB) is a well established method for diagnosis in bronchogenic cancer (CABR).


OBJECTIVE
To evaluate sensitivity and specificity of FOB in suspicious cases of lung neoplasia.


METHODS
A total of 119 suspicious cases of CABR were subjected to FOB under local anesthesia with lidocaine and sedation and bronchial brushing and lavage were carried out. In all evident lesions, a biopsy was taken. Sputum was collected in carbowax for 5 days. When histopathogic and cytopathologic studies were negative, fine needle aspiration (FNA) of the lesion was performed; if pleural involvement was present, a biopsy and a sample of liquid were taken.


RESULTS
Of 119 cases, diagnosis of CABR was confirmed by FOB in 45: brushing 25; lavage 25, and biopsy 29 with sensitivity 52.33%, specificity 100%, PPV 100%, and NPV, 42.31%. In 17, positivity was obtained in two-thirds samples; in carbowax, three were positive. In another 41 CABR-suspicious cases, all FOB samples were negative and neoplasia was confirmed by FNA in 15, biopsy of extrathoracic lymphatic node in 11, pleural biopsy in eight and liquid cytopathology in six. Non-malignant pathology was found in 33 cases: pneumonia 22, lung abscess three and tuberculosis, eight. FBO is indicated in CABR-suspicious cases. Negativity of FOB samples is due to different causes. All FOB instruments must be in optimal operative conditions and must be handled by a well-trained endoscopist.
Ortega-Carrillo
Concepción
C
Departamento de Neurología, Centro Médico "La Raza" IMSS, México.
Navarro-Reynoso
Francisco
F
Cicero-Sabido
Raúl
R
D001999:Bronchoscopy; D002283:Carcinoma, Bronchogenic / Q000473:pathology*; D005336:Fiber Optic Technology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D011446:Prospective Studies; D012680:Sensitivity and Specificity