title: Characterisation of invasive pneumococcal isolates in Catalan children up to 5 years of age, 1989-2000.
abstract: Ninety-six Streptococcus pneumoniae strains isolated between January 1989 and December 2000 from usually sterile sites of children aged < 5 years of age were included in the study. Resistance to penicillin (38.6% intermediate, 10.4% high-level), cefotaxime (20.8%), tetracycline (41.7%), chloramphenicol (33.3%) and erythromycin (27.1%), as well as serogroup/type, were related to age and pathology. Strains from children aged < 2 years showed the highest penicillin resistance rate. Resistance to penicillin, tetracycline, chloramphenicol and erythromycin was the most common pattern (18.8% of strains). Most isolates (80.2%) belonged to serogroups/types included in the heptavalent conjugate vaccine.
authors.affiliation: Microbiology Service, Hospital Sant Joan de Déu, Passeig Sant Joan de Déu 2, 08950 Esplugues, Barcelona, Spain. clatorre@hsjdbcn.org
authors.forename: C
authors.initials: C
authors.lastname: Latorre
authors.forename: A
authors.initials: A
authors.lastname: Gené
authors.forename: T
authors.initials: T
authors.lastname: Juncosa
authors.forename: C
authors.initials: C
authors.lastname: Muñoz-Almagro
authors.forename: A
authors.initials: A
authors.lastname: González-Cuevas
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000382:microbiology*; D012703:Serotyping; D013030:Spain; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents