title: Environmental effects and skin disease.
abstract: The skin is the largest organ in the body and one of its main functions is to protect the body from noxious substances, whether they are ultraviolet radiation, toxic chemicals or prolonged/repeated exposure to water. It is the level of exposure that determines if damage to the organism will result. The harm that can occur to the skin with sufficient exposure will be considered. Contact dermatitis, halogen acne, chemical depigmentation, connective tissue diseases and skin cancer are the conditions that will be covered in this chapter, as environmental exposure is important in their aetiologies. Systemic absorption will not be dealt with. Most environmental exposure to harmful substances will occur at work, but exposure may occur at home or during normal day-to-day activities.
authors.affiliation: Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham, UK. john.english@mail.qmcuh-tr.trent.nhs.uk
authors.forename: J S C
authors.initials: JS
authors.lastname: English
authors.forename: R S
authors.initials: RS
authors.lastname: Dawe
authors.forename: J
authors.initials: J
authors.lastname: Ferguson
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology; D003877:Dermatitis, Contact / Q000209:etiology; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D010126:Ozone / Q000633:toxicity; D010859:Pigmentation Disorders / Q000209:etiology; D012871:Skin Diseases / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology
chemical_list: D010126:Ozone