title: Comparison of short-term mortality risk factors for valve replacement versus coronary artery bypass graft surgery.
abstract: BACKGROUND
  Risk factors for 30-day operative (short-term) mortality following coronary artery bypass graft (CABG only) procedures are well established. However, little is known about how the risk factors for short-term mortality following valve replacement procedures (with or without a CABG procedure performed) compare with CABG only risk factors.
  
  
  METHODS
  Department of Veterans Affairs (VA) records (65,585 records) were collected from October 1991 through March 2001 and analyzed. Risk factors for short-term mortality were compared across three subgroups of patients: CABG only surgery (n = 56,318), aortic valve replacement (AVR) with or without CABG (n = 7450), and mitral valve replacement (MVR) with or without CABG (n = 1817). Multivariable logistic regression analyses were used to compare the relative magnitude of risk for 19 candidate predictor variables across subgroups.
  
  
  RESULTS
  Only three patient baseline characteristics differed significantly in magnitude of risk between the procedure groups. Partially or totally dependent functional status significantly increased the risk of short-term mortality for AVR patients (odds ratio [OR] 1.64, 95% confidence interval [CI] 1.29-2.09) and MVR patients (OR 2.21, 95% CI 1.48-3.30), but not for CABG only patients (OR 1.04, 95% CI 0.93-1.16). Conversely, previous heart surgery and New York Heart Association functional class III or IV symptoms conferred greater magnitude of risk for CABG only patients compared with the valve subgroups.
  
  
  CONCLUSIONS
  Overall, the risk factors for short-term mortality following valve replacement and CABG surgery appear to be relatively consistent. However, clinicians should be aware of the importance of preoperative functional status as a unique predictor of mortality following valve surgery.
authors.affiliation: Department of Veterans Affairs Medical Center, Denver, Colorado, USA.
authors.forename: Sheila C
authors.initials: SC
authors.lastname: Gardner
authors.forename: Gary K
authors.initials: GK
authors.lastname: Grunwald
authors.forename: John S
authors.initials: JS
authors.lastname: Rumsfeld
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Cleveland
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Schooley
authors.forename: Dexiang
authors.initials: D
authors.lastname: Gao
authors.forename: Frederick L
authors.initials: FL
authors.lastname: Grover
authors.forename: Gerald O
authors.initials: GO
authors.lastname: McDonald
authors.forename: A Laurie
authors.initials: AL
authors.lastname: Shroyer
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery; D003131:Combined Modality Therapy / Q000401:mortality; D016001:Confidence Intervals; D001026:Coronary Artery Bypass / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D015233:Models, Statistical; D015999:Multivariate Analysis; D016017:Odds Ratio; D011183:Postoperative Complications / Q000401:mortality*; D012307:Risk Factors; D016019:Survival Analysis; D014728:Veterans / Q000706:statistics & numerical data