Surgical resection of hepatocellular carcinoma. Post-operative outcome and long-term results in Europe: an overview.
A multicenter retrospective review of 1467 patients treated by liver resection (LR) for hepatocellular carcinoma (HCC) in Europe over a 13-year period showed a mean mortality rate of 10.6%, which was correlated with the extent of LR, the etiology of cirrhosis and the study period with an improvement during the last years. Improved 5-year overall survival (20-51%) and disease-free survival (20-33%) reached similar rates in cirrhotic than in non-cirrhotic patients. Overall results were similar to those reported in Asian series as far as patients and tumor characteristics were comparable.
Jaeck
Daniel
D
Centre de Chirurgie Viscérale et de Transplantation, Hôpital Universitaire de Hautepierre, Avenue Molière, Strasbourg Cedex, France. daniel.jaeck@chru-strasbourg.fr
Bachellier
Philippe
P
Oussoultzoglou
Elie
E
Weber
Jean-Christophe
JC
Wolf
Philippe
P
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005060:Europe; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D011300:Preoperative Care; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome