title: QSAR studies on psychotomimetic phenylalkylamines.
abstract: Quantitative Structure-Activity Relationship (QSAR) studies on a series of psychotomimetic phenylalkylamines have been made using a combination of Minimum Topological Difference (MTD) method and topological methodology. The topological indices used being a pool of distance-based topological indices. The regression analyses have shown that excellent results are obtained in multiparametric model containing MTD parameters, topological indices in that quantum chemical parameters has to be introduced. The predictive power of the proposed model is discussed on the basis of cross-validation parameters.
authors.affiliation: Department of Chemistry, Softvision Institute of Biotechnology, Indore, India.
authors.forename: Mamta
authors.initials: M
authors.lastname: Thakur
authors.forename: Abhilash
authors.initials: A
authors.lastname: Thakur
authors.forename: Padmakar V
authors.initials: PV
authors.lastname: Khadikar
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry* / Q000494:pharmacology*; D006213:Hallucinogens / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D021281:Quantitative Structure-Activity Relationship
chemical_list: D000814:Aniline Compounds; D006213:Hallucinogens