title: [Pleomorphic carcinoma of the large intestine].
abstract: Pleomorphic carcinoma, firstly described in the lung, is exceptional in the digestive tract. This tumor is often associated with fever and peripheral blood leukocytosis. The histological feature is characterized by giant pleomorphic often multinucleated cells with dense neutrophil infiltration and frequent phagocytosis of neutrophils by the tumor cells. Expression of epithelial markers confirm the diagnosis. The prognosis is very poor. We hereby report one case of pleomorphic carcinoma unusually situated in the large intestine, emphasizing difficulties encountered in establishing diagnosis.
authors.affiliation: Service d'Anatomie Pathologique, CHU Ambroise Paré (AP-HP), Boulogne-Billancourt.
authors.forename: Agathe
authors.initials: A
authors.lastname: Régnier
authors.forename: Catherine
authors.initials: C
authors.lastname: Julié
authors.forename: Ute
authors.initials: U
authors.lastname: Zimmermann
authors.forename: Jean-Hugues
authors.initials: JH
authors.lastname: Maillochaud
authors.forename: Bernard
authors.initials: B
authors.lastname: Nordlinger
authors.forename: Brigitte
authors.initials: B
authors.lastname: Franc
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D005334:Fever; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000473:pathology; D008875:Middle Aged