title: Cognitive and emotional dysfunction after central pontine myelinolysis.
abstract: The case of a 67-year-old right-handed Chinese man with Central Pontine Myelinolysis [CPM] is described to illustrate the resulting cognitive and emotional disturbances. A comparison of the data in this report with that in published studies suggests that ethnicity does not seem to have much effect on the symptoms of CPM. Possible underlying neural-pathological mechanisms are discussed. This case further substantiates the speculation that the brainstem plays a role in higher cognitive processes and emotional regulation.
authors.affiliation: Neuropsychology Laboratory, Department of Psychology, The University of Hong Kong, Hong Kong SAR. tmclee@hkusua.hku.hk
authors.forename: Tatia M C
authors.initials: TM
authors.lastname: Lee
authors.forename: Crystal C Y
authors.initials: CC
authors.lastname: Cheung
authors.forename: Esther Y Y
authors.initials: EY
authors.lastname: Lau
authors.forename: Amanda
authors.initials: A
authors.lastname: Mak
authors.forename: Leonard S W
authors.initials: LS
authors.lastname: Li
mesh_terms: D000342:Affective Symptoms / Q000175:diagnosis / Q000209:etiology*; D000368:Aged; D001921:Brain / Q000473:pathology; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000150:complications* / Q000175:diagnosis; D009483:Neuropsychological Tests; D012720:Severity of Illness Index