title: Cyclobutanes from Combretum albopunctatum.
abstract: A dichloromethane extract of the aerial parts of Combretum albopunctatum Suesseng afforded five phenolic compounds-three known flavonoids and two novel cyclobutane chalcone dimers. The chemical structures were determined by standard spectroscopic techniques and the structure and relative stereochemistry of one chalcone dimer, rel-(1 alpha,2 beta)-di-(2,6-dimethoxy-4-hydroxy)-benzoyl-rel-(3 alpha,4 beta)-diphenylcyclobutane, were confirmed by single crystal X-ray diffraction.
authors.affiliation: Department of Pharmaceutical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, UK.
authors.forename: David R
authors.initials: DR
authors.lastname: Katerere
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Gray
authors.forename: Alan R
authors.initials: AR
authors.lastname: Kennedy
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Nash
authors.forename: Roger D
authors.initials: RD
authors.lastname: Waigh
mesh_terms: D002599:Chalcone / Q000031:analogs & derivatives / Q000302:isolation & purification; D029765:Combretum / Q000737:chemistry*; D003503:Cyclobutanes / Q000737:chemistry* / Q000302:isolation & purification*; D019281:Dimerization; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D003503:Cyclobutanes; D010936:Plant Extracts; D002599:Chalcone