title: Giant testicular mixed germ cell tumor. a case report.
abstract: OBJECTIVE
  We report a case that we believe to be the largest example of a testicular mixed germ cell tumor with a clearly defined histology pattern.
  
  
  METHODS
  A 21-year-old patient consulted a urologist concerning a giant testicular mass. At the time of presentation the tumor measured 29 x 20 x 16 cm, with a weight of 4,850 g. Serum alpha-fetoprotein was over 15,000 ng/ml, while beta-human chorionic gonadotropin was normal. Chest X-ray and CT revealed multiple bilateral metastases. Histopathology revealed a mixed germ cell tumor containing 80% of yolk sack tumor, 10% of teratoma and 10% of embryonal carcinoma. Orchiectomy and chemotherapy were successful in the treatment of primary tumor and bilateral lung metastases.
  
  
  CONCLUSIONS
  This tumor grew to extraordinary dimensions because of the patient's failure, due to fear, lack of knowledge and embarrassment, to seek medical help and to health professionals' negligence when performing regular check-ups.
authors.affiliation: Department of Urology, Sisters of Mercy University Hospital, Zagreb, Croatia. igor.tomaskovic@vk.hinet.hr
authors.forename: Igor
authors.initials: I
authors.lastname: Tomasković
authors.forename: Tomislav
authors.initials: T
authors.lastname: Sorić
authors.forename: Davor
authors.initials: D
authors.lastname: Trnski
authors.forename: Boris
authors.initials: B
authors.lastname: Ruzić
authors.forename: Ognjen
authors.initials: O
authors.lastname: Kraus
mesh_terms: D000328:Adult; D018237:Germinoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed