title: Digital 3D reconstruction of two parahissian accessory bundles in a case of Wolff-Parkinson-White syndrome.
abstract: Three-dimensional reconstruction of digitized histological serial sections of the cardiac conduction system yielded two accessory pathways in a case of a 24-day-old male infant who died after a short period of illness with ECG findings of Wolff-Parkinson-White syndrome. In infants, the differential diagnosis of possible accessory pathways connecting the AV conduction system, atrial or ventricular septum includes dispersed conduction system tissue without connecting features. This is why three-dimensional reconstruction is necessary in order to refute or establish connectivity of cell groups as found in histological serial slice images.
authors.affiliation: Abteilung Kardiologie, Klinik Schloss Mammern, 8265 Mammern, Switzerland.
authors.forename: Christian
authors.initials: C
authors.lastname: Steffen
authors.forename: Michael
authors.initials: M
authors.lastname: Schaepman
authors.forename: Thomas
authors.initials: T
authors.lastname: Hardmeier
authors.forename: Wolf
authors.initials: W
authors.lastname: Schweitzer
mesh_terms: D001344:Autopsy / Q000379:methods*; D006329:Heart Conduction System / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007231:Infant, Newborn; D008297:Male; D008853:Microscopy / Q000379:methods; D014927:Wolff-Parkinson-White Syndrome / Q000473:pathology*