Some are old, some are new: life and death in the ICU.
We compared 560 adults hospitalized in our Medical Intensive Care Unit (MICU) to 245 ventilated babies hospitalized in our Neonatal ICU (NICU). Both ICUs had comparable mortality rates--roughly 1 patient in 5 died. The average length of hospitalization for nonsurvivors versus survivors was disproportionately short for NICU babies (13d v 33d) and long for MICU adults (15d v 12d). This phenomenon resulted in a redistribution of ICU bed-days and resources in favor of survivors for NICU babies (approximately 9 of every 10 NICU beds were devoted to babies who survived), and nonsurvivors for MICU adults (roughly 1 MICU bed in 2). Both ICUs had comparable percentages of patients predicted to die--roughly 1 patient in 3. The predictive power of an intuition of die was comparable--and not all that great. Almost one third of patients in both ICUs with a single prediction of "die in hospital" survived to be discharged. However, the likelihood of finding a neurologically normal NICU survivor after a prediction of "die" was only 5 in 100. To the extent that informed decisions can be made with 95% certainty, we may have found a foothold on the slippery ethical slope of benefit/burden calculations in the NICU. Unfortunately, we have no comparable data for MICU survivors.
Meadow
William
W
Department of Pediatrics and Critical Care Medicine, MacLean Center for Clinical Medical Ethics, The University of Chicago, Chicago, IL 60637, USA. WLM1@midway.uchicago.edu
Hall
Jesse
J
Frain
Laura
L
Ren
Yaya
Y
Pohlman
Anne
A
Plesha-Troyke
Susan
S
Gresens
Winnifred
W
Lantos
John
J
D000328:Adult; D004992:Ethics, Medical; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D015931:Intensive Care, Neonatal; D009017:Morbidity; D009026:Mortality; D011379:Prognosis