Early onset of severe diabetes mellitus-related microvascular complications.
A 16-year-old girl with type 1 diabetes developed painful peripheral neuropathy within 1 month and proliferative retinopathy within 1 year despite excellent glycemic control. We speculate on potential mechanisms that may have contributed to the rapid development of diabetes mellitus-related complications.
Hamilton
Jill
J
Departments of Pediatrics and Medicine, the Hospital for Sick Children and University Health Network, University of Toronto, Toronto, Ontario, Canada. jill.hamilton@sickkids.ca
Brown
Mijin
M
Silver
Robert
R
Daneman
Denis
D
D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications*; D003929:Diabetic Neuropathies / Q000209:etiology*; D003930:Diabetic Retinopathy / Q000209:etiology*; D005260:Female; D006801:Humans
D001786:Blood Glucose