title: Reconstruction of maxillectomy defect by transport distraction osteogenesis.
abstract: The study aimed to explore the feasibility of posterior maxillectomy reconstruction by transport distraction in a primate model. In each of 14 male adult rhesus monkeys, posterior partial maxillectomy was performed on one side of maxilla to create a posterior maxillary deflect. Immediately after the maxillectomy, a dentoalveolar segment anterior to the defect was osteotomized as transport segment and a custom-made transport distractor was fixed on the residual maxilla. After a latency period of 5 days, the distractor was activated 1 mm daily to move the transport segment backward to the defect. This process lasted about 2 weeks. The transport segment was allowed to consolidate and the animals were sacrificed at different defined intervals. Transport distraction was successful in six animals. Three other cases were completed with minor wound dehiscence and one had a small oro-antral fistula with subsequent maxillary sinusitis. New bone bridging the distraction gap was confirmed by radiography and histology in the animals completing distraction. Reconstruction of posterior maxillectomy defect is proven feasible by transport distraction osteogenesis.
authors.affiliation: Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China. lkcheung@hkucc.hku.hk
authors.forename: L K
authors.initials: LK
authors.lastname: Cheung
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.forename: Z G
authors.initials: ZG
authors.lastname: Zhang
authors.forename: M C M
authors.initials: MC
authors.lastname: Wong
mesh_terms: D000539:Alveolar Process / Q000637:transplantation*; D000818:Animals; D001860:Bone Plates; D001861:Bone Regeneration / Q000502:physiology*; D016025:Bone Transplantation; D004867:Equipment Design; D016268:Internal Fixators; D019248:Jaw Fixation Techniques / Q000295:instrumentation; D008253:Macaca mulatta; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging / Q000601:surgery*; D019857:Osteogenesis, Distraction / Q000295:instrumentation / Q000379:methods*; D010027:Osteotomy / Q000534:rehabilitation; D011859:Radiography