Direct optical resolution of the enantiomers of novel chiral tetrahedral metal clusters by HPLC on a cellulose tris-(3,5-dimethylphenylcarbamate) stationary phase.
The enantioseparation of seven novel chiral transition metal tetrahedral clusters has been achieved for the first time on cellulose derivatized with tris(3,5-dimethylphenylcarbamate) (CDMPC) as chiral stationary phase (CSP) and hexane containing different alcohols as modifiers as mobile phases. The effect of mobile-phase composition on enantioselectivity was studied, and the effect of structural variation of the solutes on their enantioseparation was also investigated. It was found that both the metal in the tetrahedral core and the ligand coordinated to the atom in the tetrahedral core had significant effects on the chromatographic behavior of the analytes.
Li
Wenzhi
W
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Tianshui Road 342, 730000, Lanzhou, P.R. China.
Zhang
Weiqiang
W
Zhao
Quanyi
Q
Li
Yongmin
Y
Ma
Chunlin
C
Chen
Liren
L
Yin
Yuanqi
Y
D000438:Alcohols / Q000737:chemistry; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D008968:Molecular Conformation; D055095:Optics and Photonics; D009942:Organometallic Compounds / Q000032:analysis*; D048448:Phenylcarbamates / Q000737:chemistry*; D012153:Retention, Psychology; D013237:Stereoisomerism; D013997:Time Factors
D000438:Alcohols; D009942:Organometallic Compounds; D048448:Phenylcarbamates; C065943:cellulose tris-3,5-dimethylphenyl-carbamate; D002482:Cellulose