[Radionuclide pulmonary perfusion imaging in evaluating pulmonary hypertension in patients with rheumatic heart disease].
OBJECTIVE
To evaluate the degree of pulmonary hypertension in patients with rheumatic heart disease using radionuclide pulmonary perfusion imaging.


METHODS
The pulmonary perfusion in 25 patients with rheumatic heart disease was examined using scintigram with macroaggregates of (99m)Tc-labeled human serum albumin (PPS) before and 7 days after operation. PPS was analyzed for (1) pulmonary perfusion steady time (PT), right upper and lower lung count ratio (RULR). The results were compared with those of catheterization examination during the operation.


RESULTS
The pulmonary arterial systolic pressure (PAs) and total pulmonary resistance (TPR) were (60 +/- 21) mm Hg and (421 +/- 106) dyn if PT > or = 20 seconds and RULR > or = 2; The PAs and TPR were (28 +/- 5) mm Hg and (188 +/- 28) dyn if PT < 20 seconds and RULR < 2. The PPS changed in most of the patients during early operation.


CONCLUSIONS
The degree of injury in pulmonary vascular in patients with rheumatic heart disease could be quantitatively analysed by PPS.
Pan
Shi-wei
SW
Department of Surgery, Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100037, China.
Hu
Sheng-shou
SS
Wu
Qing-yu
QY
Song
Yun-hu
YH
Wang
Xue-mei
XM
Shi
Rong-fang
RF
Yu
Qi-bin
QB
Yang
Ke-ming
KM
Liu
Sheng
S
D000328:Adult; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011652:Pulmonary Circulation; D011877:Radionuclide Imaging; D012214:Rheumatic Heart Disease / Q000150:complications*; D013599:Systole; D013668:Technetium Tc 99m Aggregated Albumin; D014655:Vascular Resistance
D013668:Technetium Tc 99m Aggregated Albumin