Structural aspects of Golgi function.
Since its discovery, the Golgi complex has attracted the attention of cell biologists because of its 'fashionable' morphology and central position within the secretory system of the cell. Here, we discuss how the three-dimensional architecture of the Golgi complex relates to its multiple functions in protein sorting and processing, and how an analysis of the morphology of the Golgi complex can help to provide an understanding of the mechanisms involved in transport through this unique organelle.
Polishchuk
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RS
Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, Department of Cell Biology and Oncology, Via Nazionale, 66030 Santa Maria Imbaro, Chieti, Italy. polish@negrisud.it
Mironov
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AA
D000818:Animals; D022181:COP-Coated Vesicles / Q000502:physiology; D020755:Coat Protein Complex I / Q000502:physiology; D006056:Golgi Apparatus / Q000502:physiology* / Q000648:ultrastructure*; D006801:Humans; D021381:Protein Transport / Q000502:physiology
D020755:Coat Protein Complex I