title: CT perfusion of the liver during selective hepatic arteriography: pure arterial blood perfusion of liver tumor and parenchyma.
abstract: OBJECTIVE
  To quantify pure arterial blood perfusion of liver tumor and parenchyma by using CT perfusion during selective hepatic arteriography.
  
  
  METHODS
  A total of 44 patients underwent liver CT perfusion study by injection of contrast medium via the hepatic artery. CT-perfusion parameters including arterial blood flow, arterial blood volume, and arterial mean transit time in the liver parenchyma and liver tumor were calculated using the deconvolution method. The CT-perfusion parameters and vascularity of the tumor were compared.
  
  
  RESULTS
  A complete analysis could be performed in 36 of the 44 patients. For liver tumor and liver parenchyma, respectively, arterial blood flow was 184.6 +/- 132.7 and 41.0 +/- 27.0 ml/min/ 100 g, arterial blood volume was 19.4 +/- 14.6 and 4.8 +/- 4.2 ml/100 g, and arterial mean transit time was 8.9 +/- 4.2 and 10.2 +/- 5.3 sec. Arterial blood flow and arterial blood volume correlated significantly with the vascularity of the tumor; however no correlation was detected between arterial mean transit time and the vascularity of the tumor.
  
  
  CONCLUSIONS
  This technique could be used to quantify pure hepatic arterial blood perfusion.
authors.affiliation: Department of Radiology, Kansai Medical University, Moriguchi-city, Osaka 570-8507, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Komemushi
authors.forename: Noboru
authors.initials: N
authors.lastname: Tanigawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kojima
authors.forename: Shuji
authors.initials: S
authors.lastname: Kariya
authors.forename: Satoshi
authors.initials: S
authors.lastname: Sawada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006499:Hepatic Artery / Q000000981:diagnostic imaging*; D006801:Humans; D007479:Iopamidol / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007479:Iopamidol