Preoperative psychological reactions and quality of life among women with an increased risk of breast cancer who are considering a prophylactic mastectomy.
A consecutive sample of 56 women with a familial risk for breast cancer who were considering a prophylactic mastectomy (PM) completed questionnaires preoperatively concerning risk perception, expectations with regard to surgery, anxiety and depressive symptoms (the Hospital Anxiety and Depression Scale (HAD) scale) and quality of life (The Swedish SF-36 Health Survey). 16 had had a previous breast cancer (Group BC) and 40 had not (Group R). They were compared with normative data from an age-matched random sample of the Swedish population and with a reference sample of women with breast cancer. Most women estimated their breast cancer risk accurately. No statistically significant differences were found between Group BC and the normative sample on the HAD scale and SF-36, but Group R reported better physical functioning, emotional role functioning and mental health than the reference sample with breast cancer. Group BC scored closer to them than to the normative sample. Levels of emotional problems and quality of life were comparable to normative values among women considering PM. All women in the present study had previous genetic counselling and our results suggest that their interest in PM was not due to an overestimation of their personal risk.
Brandberg
Y
Y
Department of Oncology and Pathology, Radiumhemmet, Karolinska University Hospital, S-171 76 Stockholm, Sweden. yvonne.brandberg@onkpat.ki.se
Arver
B
B
Lindblom
A
A
Sandelin
K
K
Wickman
M
M
Hall
P
P
D000328:Adult; D000368:Aged; D001007:Anxiety / Q000209:etiology; D001294:Attitude to Health; D001943:Breast Neoplasms / Q000517:prevention & control / Q000523:psychology* / Q000601:surgery; D003863:Depression / Q000209:etiology; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D006801:Humans; D008408:Mastectomy / Q000379:methods / Q000523:psychology*; D008875:Middle Aged; D017060:Patient Satisfaction; D011300:Preoperative Care; D011788:Quality of Life; D012307:Risk Factors; D011795:Surveys and Questionnaires