Facile and effective copper-mediated cyclization reaction of cyclopropylideneacetic acids (or esters) and cyclopropylideneacetonitriles.
The full details of the copper-mediated cyclization reaction of cyclopropylideneacetic acids (or esters) and cyclopropylidenenitriles, the synthetic application of this reaction, and the study of the reaction mechanism are reported.
Huang
Xian
X
Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou 310028, P.R. China. huangx@mail.hz.zj.cn
Zhou
Hongwei
H
Chen
Wanli
W