title: Walking difficulties in patients with Alzheimer's disease might originate from gait apraxia.
abstract: OBJECTIVE
  To investigate whether gait apraxia is a possible cause for some of the walking abnormalities shown by patients with Alzheimer's disease.
  
  
  METHODS
  60 patients with Alzheimer's disease, selected as being free from overt extrapyramidal impairment or other potential causes of walking deficits, were assessed with a new test evaluating aspects of walking and related movements. Norms for this test were collected from a sample of 182 healthy volunteers.
  
  
  RESULTS
  40% of the Alzheimer group performed below the cut off score on this test, and half performed poorly. Performance of the Alzheimer group in the walking skills test correlated highly with scores in a test assessing limb apraxia and with dementia severity.
  
  
  CONCLUSIONS
  Gait apraxia may be the cause of walking disorders found in a subgroup of patients with Alzheimer's disease. Its detection is made easier by the use of a standardised test, but still relies heavily on the exclusion of other causes of walking deficits. It is a recognisable and independent form of apraxia.
authors.affiliation: Neuropsychology Research Group, School of Psychology, University of Aberdeen, Aberdeen, UK. sergio@abdn.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Della Sala
authors.forename: H
authors.initials: H
authors.lastname: Spinnler
authors.forename: A
authors.initials: A
authors.lastname: Venneri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications*; D005260:Female; D020235:Gait Apraxia / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D016138:Walking