title: Predictors of tonsillar tissue HIV-1 viral burden at baseline and after 1 year of antiretroviral therapy.
abstract: In 81 antiretroviral-navie HIV-1 chronic-infected patients, we found a correlation among tonsillar tissue viral load, and virological and immunological measures in blood at baseline. No correlation was observed after 1 year of antiretroviral therapy. A protease inhibitor-containing regimen was the best predictor of good tonsillar tissue virological response.
authors.affiliation: Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Faculty of Medicine, University of Barcelona, Barcelona, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Navarrete
authors.forename: Vanessa
authors.initials: V
authors.lastname: Morente
authors.forename: Felipe
authors.initials: F
authors.lastname: García
authors.forename: Lluçia
authors.initials: L
authors.lastname: Alós
authors.forename: Mireia
authors.initials: M
authors.lastname: Arnedo
authors.forename: Montserrat
authors.initials: M
authors.lastname: Plana
authors.forename: Cristina
authors.initials: C
authors.lastname: Gil
authors.forename: Miguel
authors.initials: M
authors.lastname: Caballero
authors.forename: José M
authors.initials: JM
authors.lastname: Miró
authors.forename: Esteban
authors.initials: E
authors.lastname: Martínez
authors.forename: Emilio
authors.initials: E
authors.lastname: Fumero
authors.forename: Pedro
authors.initials: P
authors.lastname: Castro
authors.forename: José L
authors.initials: JL
authors.lastname: Blanco
authors.forename: Josep
authors.initials: J
authors.lastname: Mallolas
authors.forename: José L
authors.initials: JL
authors.lastname: Blanch
authors.forename: Anna
authors.initials: A
authors.lastname: Cruceta
authors.forename: Gabriel
authors.initials: G
authors.lastname: Mestre
authors.forename: Tomás
authors.initials: T
authors.lastname: Pumarola
authors.forename: Teresa
authors.initials: T
authors.lastname: Gallart
authors.forename: José M
authors.initials: JM
authors.lastname: Gatell
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000821:virology; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D014066:Palatine Tonsil / Q000821:virology*; D019562:Viral Load; D014766:Viremia / Q000821:virology
chemical_list: D019380:Anti-HIV Agents