title: Switching extended 1,3-diequatorial and bent 1,3-diaxial states of a disubstituted hinge sugar by ligand exchange reactions on Pt(II).
abstract: The bent conformation of a trisaccharide containing 2,4-diaminoxylopyranoside, in which both end sugars are presented in 1,3-diaxial orientation, is fixed by chelation of the diamino groups to Pt(II) and unfixed by a ligand exchange reaction with NaCN or thiourea giving its extended conformation.
authors.affiliation: Department of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsutacho, Midoriku, Yokohama 2268501, Japan.
authors.forename: Takuhiro
authors.initials: T
authors.lastname: Izumi
authors.forename: Hironobu
authors.initials: H
authors.lastname: Hashimoto
authors.forename: Hideya
authors.initials: H
authors.lastname: Yuasa
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D008024:Ligands; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009944:Organoplatinum Compounds / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*; D012966:Sodium Cyanide / Q000737:chemistry; D013890:Thiourea / Q000737:chemistry; D014312:Trisaccharides / Q000737:chemistry*
chemical_list: D008024:Ligands; D009944:Organoplatinum Compounds; D014312:Trisaccharides; D010984:Platinum; D013890:Thiourea; D012966:Sodium Cyanide