title: Remission of collapsing focal segmental glomerulosclerosis following chemotherapy for myeloma.
abstract: Collapsing focal segmental glomerulosclerosis can be idiopathic but has been associated with human immunodeficiency virus infection as well as lymphoproliferative, myeloproliferative, and autoimmune disorders. It has a more rapid progression to end-stage renal failure. Treatment of this condition is poorly defined with no clear evidence of response to any treatment regimens. We report a case of collapsing focal segmental glomerulosclerosis in association with multiple myeloma that underwent partial remission following treatment for the underlying disease.
authors.affiliation: Department of Renal Medicine, Barts and the London NHS Trust, London, UK.
authors.forename: Sapna
authors.initials: S
authors.lastname: Shah
authors.forename: Jamie
authors.initials: J
authors.lastname: Cavenagh
authors.forename: Michael
authors.initials: M
authors.lastname: Sheaf
authors.forename: Raj C
authors.initials: RC
authors.lastname: Thuraisingham
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy*; D012074:Remission Induction; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D003907:Dexamethasone; D004317:Doxorubicin