title: [Transcatheter closure of atrial septal defects in 40 pediatric patients].
abstract: OBJECTIVE
  To evaluate the clinical efficiency of transcatheter closure of atrial septal defect (ASD) with AGA-Amplatzer occlusion device in pediatric patients.
  
  
  METHODS
  Forty patients with ASD, 16 males, 24 females, at a mean age of 10.2 years (ranged from 3 to 15 years of age) and with a mean weight of 35.8 kg (ranged from 11 to 87 kg) were studied. Six cases were complicated with pulmonary stenosis (PS), 1 was complicated with ventricular tachycardia (VT). Right heart catheterizations were done in 40 patients for measuring the pressures of right ventricle and pulmonary artery. The balloon diameter of ASD was measured using balloon catheter with guiding wire. The diameter of ASD was measured by TTE and/or TEE, ascertaining the location and size of ASD. Amplatzer occlusion device was sized to be equal to or 1 - 2 mm more than the diameter of balloon stretched.
  
  
  RESULTS
  All patients had successful implantation of the Amplatzer device. The success rate was 100%. The diameter measured by TTE was 7 - 30 mm (mean 17.12 mm). The diameter measured by TEE was 7 - 32 mm (mean 18.44 mm). The diameter of balloon stretched of ASD was 8 - 34 mm. Of the 40 cases, 6 were complicated with PS and accepted percutaneous balloon valvuloplasty (PBPV). One case was complicated with VT and accepted radiofrequency catheter ablation (RFCA). Neither complication nor residual shunt was found in any of the patients. The patients were recovered and followed up for 3 or 4 days after deployment of the Amplatzer device. Clinical symptom, cardiac murmur, and findings in ECG, echocardiography and X-ray were improved markedly.
  
  
  CONCLUSIONS
  AGA-Amplatzer occlusion device is safe and efficient in pediatric patients with ASD.
authors.affiliation: Department of Internal Medicine For Congenital Heart Diseases, Shenyan Military General Hospital, Shenyang 110016, China.
authors.forename: Dong-an
authors.initials: DA
authors.lastname: Deng
authors.forename: Xian-yang
authors.initials: XY
authors.lastname: Zhu
authors.forename: Chuan-ju
authors.initials: CJ
authors.lastname: Hou
authors.forename: Xiu-min
authors.initials: XM
authors.lastname: Han
authors.forename: Qi-guang
authors.initials: QG
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Jin
authors.forename: Wei
authors.initials: W
authors.lastname: Quan
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Shu-fan
authors.initials: SF
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D006328:Cardiac Catheterization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006801:Humans; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care; D016896:Treatment Outcome