title: Acellular dermal matrix allograft used to gain attached gingiva in a case of epidermolysis bullosa.
abstract: BACKGROUND
  Epidermolysis bullosa (EB) is an acquired disease or inherited as either autosomal dominant or recessive with an incidence of 1/50,000. The prominent clinical characteristic of the disease is the development of bullae or vesicles in mucosa or skin in response to minor trauma.
  
  
  OBJECTIVE
  A female patient with a dystrophic type of EB had been put in a maintenance regimen after completion of the initial phase of periodontal therapy and followed for 7 years. The purpose of this report is to document acellular dermal matrix allograft application to increase the width of the attached gingiva in this patient experiencing difficulty in chewing and performing plaque control due to the dramatic loss of attached gingiva after 7 years of supportive periodontal therapy.
  
  
  METHODS
  Under local anaesthesia and antibiotic coverage, the acellular dermal matrix allograft was applied in the anterior region of the upper jaw in order to increase the width of attached gingiva, thereby improving patient comfort.
  
  
  RESULTS
  The healing was uneventful and a significant gain in attached gingiva dimensions was observed 9 months after the periodontal surgery. The procedure avoided a second surgical site, provided satisfactory results from an aesthetic point of view, and improved patient comfort.
  
  
  CONCLUSIONS
  Acellular dermal matrix allograft may be regarded as an alternative in the treatment of EB cases to increase the width of attached gingiva and facilitate maintenance of the dentition.
authors.affiliation: Faculty of Dentistry, Department of Periodontology, Ege University, Izmir, Turkey. eralp@bornova.egeedu.tr
authors.forename: Eralp
authors.initials: E
authors.lastname: Buduneli
authors.forename: Tunç
authors.initials: T
authors.lastname: Ilgenli
authors.forename: Nurcan
authors.initials: N
authors.lastname: Buduneli
authors.forename: Fezal
authors.initials: F
authors.lastname: Ozdemir
mesh_terms: D000293:Adolescent; D003094:Collagen / Q000627:therapeutic use*; D017742:Dental Care for Chronically Ill; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications*; D005109:Extracellular Matrix / Q000637:transplantation; D005260:Female; D005881:Gingiva / Q000473:pathology / Q000601:surgery; D005889:Gingival Recession / Q000209:etiology / Q000628:therapy*; D005893:Gingivoplasty / Q000379:methods*; D006801:Humans; D010512:Periodontal Index; D016038:Skin Transplantation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D003094:Collagen