title: [Surgical management of hypopharyngeal cancer].
abstract: OBJECTIVE
  To investigate the preservation of laryngeal function for the patients with hypopharyngeal cancer.
  
  
  METHODS
  Two hundred and ninety-three cases of hypopharyngeal cancer with surgical management were reviewed retrospectively, and 222 cases were originated from pyriform sinus, 13 from post-cricoid, and 21 from posterior pharyngeal wall. Radiotherapy (37 cases), operation only (56 cases) and the combined treatment (operation plus radiation or chemotherapy, 200 cases) were adopted. 159 cases were treated with function preserved laryngectomy and 97 with total laryngectomy.
  
  
  RESULTS
  The 5 year survival rates of patient with laryngeal function preserved and no laryngeal function preserved were 51.3%, 47.6% (for stage III); 40.4%, 43.3% (for stage IV), respectively. There were no significant differences in 5-year survival between the functionally preserved group and no functioned group (P > 0.05). The analysis of survival rates revealed a significant difference between combined therapy and radiotherapy.
  
  
  CONCLUSIONS
  There is no significant difference between the survive rates of function preserved and non-preserved groups. Conservation laryngectomy improves the quality of patient's life, and combined therapy is the best choice for hypopharyngeal cancer.
authors.affiliation: Department of Otorhinolaryngology, Affiliated Hospital of Bengbu, Medical University, Bengbu 233004, China. jyl606@263.net
authors.forename: Feng
authors.initials: F
authors.lastname: Yu
authors.forename: Yu-li
authors.initials: YL
authors.lastname: Dong
authors.forename: Zhi-jiang
authors.initials: ZJ
authors.lastname: Zu
authors.forename: Xiao-dong
authors.initials: XD
authors.lastname: Zhan
authors.forename: Ji-hong
authors.initials: JH
authors.lastname: Shu
authors.forename: Jia-shu
authors.initials: JS
authors.lastname: Yang
authors.forename: Guang-sheng
authors.initials: GS
authors.lastname: Han
authors.forename: Ling-chuan
authors.initials: LC
authors.lastname: Lu
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.forename: Hui-juan
authors.initials: HJ
authors.lastname: Sun
authors.forename: Ke-jie
authors.initials: KJ
authors.lastname: Ren
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy; D007830:Larynx / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D019651:Plastic Surgery Procedures; D015996:Survival Rate; D016896:Treatment Outcome