title: Successful treatment of pure red cell aplasia in systemic lupus erythematosus with cyclosporin A.
abstract: We report a patient with longstanding systemic lupus erythematosus (SLE) who developed pure red cell aplasia (PRCA). This condition is rare in connective tissue diseases and is reported in 32 previous cases of SLE in literature. Our patient recovered, apparently in response to treatment with high dosage of corticosteroids, but relapse occurred when the prednisone dosage was tapered down to 10 mg/day. The patient was successfully treated with cyclosporin A with no recurrence of the disease in the last 2 years.
authors.affiliation: Department of Rheumatology, L. Sacco University Hospital, Milan, Italy. atzenifabiola@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Atzeni
authors.forename: P
authors.initials: P
authors.lastname: Sarzi-Puttini
authors.forename: F
authors.initials: F
authors.lastname: Capsoni
authors.forename: L
authors.initials: L
authors.lastname: Vulpio
authors.forename: M
authors.initials: M
authors.lastname: Carrabba
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D016572:Cyclosporine