title: The validity of the MacNew Quality of Life in heart disease questionnaire.
abstract: BACKGROUND
  A previous review suggested that the MacNew Quality of Life Questionnaire was the most appropriate disease-specific measure of health-related quality of life among people with ischaemic heart disease. However, there is ambiguity about the allocation of items to the three factors underlying the MacNew and the factor structure has not been confirmed previously among the people in the UK.
  
  
  METHODS
  The MacNew Questionnaire and the SF-36 were administered to 117 newly admitted patients to a tertiary referral centre in Northern Ireland. All patients had been diagnosed with ischaemic heart disease.
  
  
  RESULTS
  A confirmatory factor analysis was conducted on the factor structure of the MacNew and the model was found to be an inadequate fit of the data. A quantitative and qualitative analysis of the items suggested that a five factor solution was more appropriate and this was validated by confirmatory factor analysis. This new structure also displayed strong evidence of concurrent validity when compared to the SF-36.
  
  
  CONCLUSIONS
  We recommend that researchers should submit scores obtained from items on the MacNew to secondary analyses after being grouped according to the factor structure proposed in this paper, in order to explore further the most appropriate grouping of items.
authors.affiliation: School of Psychology, Queen's University, David Keir Building, 18-30 Malone Road Belfast, UK. m.dempster@qub.ac.uk
authors.forename: Martin
authors.initials: M
authors.lastname: Dempster
authors.forename: Michael
authors.initials: M
authors.lastname: Donnelly
authors.forename: Christina
authors.initials: C
authors.lastname: O'Loughlin
mesh_terms: D000368:Aged; D005163:Factor Analysis, Statistical; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology* / Q000523:psychology / Q000534:rehabilitation; D009660:Northern Ireland; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life; D012017:Referral and Consultation; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires / Q000592:standards*