[Role of calcium and magnesium ions in cerebrospinal fluid in alcoholic-traumatic coma].
The goal of investigation was to determine the role of calcium and magnesium ions in the cerebrospinal fluid in ethylic-traumatic coma. We measured the level of calcium in the cerebrospinal fluid within simple photometric test and the magnesium level within xylidyl blue photometric test. We found a high mortality in patients with high level of calcium in cerebrospinal fluid and low level of magnesium in cerebrospinal fluid. At patients with ethylic-traumatic coma high levels of calcium in cerebrospinal fluid are caused by the excitatory amino acids cascade and increased of hematoencephalic barrier permeability. Decreased levels of magnesium in cerebrospinal fluid are associated with convulsions and a poor prognosis of the patients. These analyses are very important for establishment of prognosis in patients with ethylic-traumatic coma.
Bologa
Cristina
C
Clinica Medicală, Spitalul Clinic de Urgente, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Rusu
M
M
Ianovici
N
N
Tetraru
C
C
Hurjui
J
J
Petriş
O
O
Lionte
Cătălina
C
D000328:Adult; D000437:Alcoholism / Q000134:cerebrospinal fluid* / Q000150:complications; D015415:Biomarkers / Q000134:cerebrospinal fluid; D002118:Calcium / Q000134:cerebrospinal fluid*; D002555:Cerebrospinal Fluid / Q000378:metabolism*; D020207:Coma, Post-Head Injury / Q000134:cerebrospinal fluid* / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D008274:Magnesium / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D015415:Biomarkers; D008274:Magnesium; D002118:Calcium