title: Balloon angioplasty as a treatment of failing infrainguinal autologous vein bypass grafts.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the role of balloon angioplasty in the treatment of failing infrainguinal vein bypass (IVB) grafts.
  
  
  METHODS
  A retrospective chart review of patients undergoing revision of a failing IVB graft by vascular surgeons at a tertiary care center from 1990 to 2001 was performed. Failing bypass grafts were identified by routine duplex scan surveillance and physical examination. The criteria for endovascular intervention varied on the basis of surgeon preferences and time period; factors considered when choosing balloon angioplasty included significant comorbidities that precluded operative intervention, the lack of adequate conduit for surgical revision, or poor accessibility of the stenotic lesion. Data recorded included demographic patient data, type of IVB graft, patency status, further procedures performed, and all complications and mortalities. Cumulative primary and assisted patency rates were calculated by using Kaplan-Meier life-table analysis.
  
  
  RESULTS
  A total of 45 balloon angioplasties were performed in 36 patients. There were 36 angioplasties of vein bypass grafts, and additional balloon angioplasties were performed on nine of these patients. Locations of IVB grafts included femoropopliteal (13 patients), femorodistal (13), and popliteal to distal (10). Initial success was achieved in 33 of 36 vein bypass grafts (91.7%). In these bypass grafts, the stenotic lesions were identified and treated at the proximal anastomosis (3 patients), mid-bypass graft (6 patients), and distal anastomosis (27 patients). Autogenous vein was used for all bypass grafts. Cumulative vein bypass graft (life-table analysis) primary patency rates (those free of occlusion or bypass graft threatening stenosis) were 74.2% at 6 months, 62.7% at 12 months, and 58.2% at 24 months. Repeat interventions included surgical thrombectomy with vein patch angioplasty or bypass graft revision, as well as repeat balloon angioplasty with or without thrombolysis. Cumulative assisted vein bypass graft patency rates (those free of occlusion or bypass graft threatening stenosis) were 87.0%, 83.2%, and 78.9% at 6, 12, and 24 months, respectively. Two patients (4%) developed thigh hematomas; no other procedure-related complications were noted, and there were no deaths in the perioperative period.
  
  
  CONCLUSIONS
  Balloon angioplasty of failing infrainguinal vein bypass grafts can be successfully performed with a low rate of complications. Acceptable short-term patency can be achieved. This procedure should be considered as an initial option in failing IVB grafts.
authors.affiliation: Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242-1086, USA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Carlson
authors.forename: Jamal J
authors.initials: JJ
authors.lastname: Hoballah
authors.forename: William J
authors.initials: WJ
authors.lastname: Sharp
authors.forename: Mario
authors.initials: M
authors.lastname: Martinasevic
authors.forename: Kerri
authors.initials: K
authors.lastname: Maiers Yelden
authors.forename: John D
authors.initials: JD
authors.lastname: Corson
authors.forename: Timothy F
authors.initials: TF
authors.lastname: Kresowik
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon; D001166:Arteriovenous Shunt, Surgical; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D005260:Female; D006083:Graft Occlusion, Vascular / Q000628:therapy*; D006801:Humans; D015993:Life Tables; D008297:Male; D011183:Postoperative Complications / Q000628:therapy*; D011475:Prosthesis Failure; D012189:Retrospective Studies; D013997:Time Factors; D014654:Vascular Patency