title: Aleukaemic leukaemia cutis: case report and review of the literature.
abstract: 'Aleukaemic leukaemia cutis' or acute leukaemia confined to the skin is extremely rare, although skin involvement with underlying leukaemia is well recognized, and is associated with a poor prognosis. We report a case of isolated acute myeloid leukaemia (AML) in the skin. A literature review shows this to be commonly misdiagnosed. Its recognition is important, because early diagnosis should lead to more appropriate chemotherapy, and a better prognosis. These patients probably require therapy directed specifically to the skin, as well as to other extramedullary sites, such as the central nervous system, to prevent early relapse.
authors.affiliation: Department of Haematology, St Richard's Hospital, Chichester, UK.
authors.forename: R
authors.initials: R
authors.lastname: Wilkins
authors.forename: S
authors.initials: S
authors.lastname: Janes
mesh_terms: D024221:Antineoplastic Protocols; D001853:Bone Marrow / Q000473:pathology; D002490:Central Nervous System / Q000473:pathology; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000473:pathology*; D017254:Leukemic Infiltration / Q000473:pathology / Q000517:prevention & control; D008875:Middle Aged; D011379:Prognosis; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*