title: The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ): a validation.
abstract: BACKGROUND
  We wished to evaluate the psychometric properties of the Polycystic Ovary Syndrome Questionnaire (PCOSQ), a questionnaire developed to measure the health-related quality of life (HRQoL) of women with polycystic ovary syndrome.
  
  
  METHODS
  To assess reliability and validity, women recruited from an outpatient gynaecology clinic at the Jessop Wing, Royal Hallamshire Hospital, Sheffield completed two copies of the PCOSQ and the Short Form-36 (SF-36). Secondary factor analysis was carried out to verify the composition of the dimensions. Semi-structured interviews were conducted to assess face validity.
  
  
  RESULTS
  Of the 92 women who consented, 82 women (89%) returned questionnaires at time 1, and 69 women (75%) returned questionnaires at time 2. All five PCOSQ dimensions were internally reliable with Cronbach's alpha scores ranging from 0.70 to 0.97. Intra-class correlation coefficients to evaluate test-retest reliability were high (range 0.89-0.95, P < 0.001). Construct validity was demonstrated by high correlations for all comparisons of similar scales of the SF-36 and PCOSQ (0.49 and 0.54). Acne was identified as an important area of HRQoL missing from the questionnaire.
  
  
  CONCLUSIONS
  The PCOSQ is a reliable instrument for measuring the HRQoL in women with PCOS. However, the validity of the questionnaire needs to be improved by incorporating a dimension on acne into the instrument.
authors.affiliation: University of Sheffield Institute of General Practice and Primary Care, Community Sciences Building, Herries Rd, Northern General Hospital, Sheffield S5 7AU, UK. G.L.Jones@sheffield.ac.uk
authors.forename: G L
authors.initials: GL
authors.lastname: Jones
authors.forename: K
authors.initials: K
authors.lastname: Benes
authors.forename: T L
authors.initials: TL
authors.lastname: Clark
authors.forename: R
authors.initials: R
authors.lastname: Denham
authors.forename: M G
authors.initials: MG
authors.lastname: Holder
authors.forename: T J
authors.initials: TJ
authors.lastname: Haynes
authors.forename: N C
authors.initials: NC
authors.lastname: Mulgrew
authors.forename: K E
authors.initials: KE
authors.lastname: Shepherd
authors.forename: V H
authors.initials: VH
authors.lastname: Wilkinson
authors.forename: M
authors.initials: M
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Balen
authors.forename: H
authors.initials: H
authors.lastname: Lashen
authors.forename: W L
authors.initials: WL
authors.lastname: Ledger
mesh_terms: D000152:Acne Vulgaris; D000328:Adult; D004644:Emotions; D005006:Ethnicity; D005260:Female; D006304:Health Status; D006801:Humans; D007246:Infertility; D008599:Menstruation Disturbances; D008603:Mental Health; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000523:psychology*; D011788:Quality of Life; D011795:Surveys and Questionnaires