title: [Malignant fibrous histiocytomas of larynx].
abstract: OBJECTIVE
  To explore the histopathology, diagnosis and treatment of malignant fibrous histiocytomas (MFH) of larynx.
  
  
  METHODS
  The clinical and pathologic features of 9 cases with MFH of larynx were reviewed retrospectively.
  
  
  RESULTS
  All the 9 cases with MFH of larynx were adults (the age ranged from 43 to 87 years; average 56 years); 8 were men and 1 woman. The tumor of eight cases originated in glottic area and 1 case occurred in supraglottic area. The histological diagnosis was difficult, so the immunohistochemical studies in 5 cases were examined. Because surgical resection was a mainly treatment, seven patients underwent total laryngectomy and 2 cases underwent frontal partial laryngectomy. Six patients were followed up for more than 3 years and no patient died of MFH after surgical resection.
  
  
  CONCLUSIONS
  The diagnosis of MFH of larynx was sometimes difficult and immunohistochemistry could be helpful. The mainly treatment of MFH of larynx was surgical resection by total laryngectomy or partial laryngectomy.
authors.affiliation: Department of Otorhinolaryngology, EENT Hospital, Fu Dan University, Shanghai 200031, China. wu941103@online.sh.cn
authors.forename: Hai-tao
authors.initials: HT
authors.lastname: Wu
authors.forename: Cai
authors.initials: C
authors.lastname: Li
authors.forename: Yun-fang
authors.initials: YF
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies