A new route to furanoeremophilane sesquiterpenoids. Synthesis of (+/-)-6[small beta]-hydroxyeuryopsin.
The naturally occurring furanoeremophilane 6[small beta]-hydroxyeuryopsin was synthesized by a novel route which involved Stille coupling of a 2-furylstannane with a cyclohexylmethyl bromide, followed by intramolecular formylation of the furan to complete the tricyclic nucleus of the sesquiterpenoid.
Shanmugham
M Sundaram
MS
Department of Chemistry, Oregon State University, Corvallis, Oregon 97331-4003, USA.
White
James D
JD