title: Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion.
abstract: The channel-forming diglycolylated heptapeptides containing the amino acid sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly have been found to complex chloride in CDCl(3). The strength of the interaction depends on the terminal alkyl groups and on chloride's countercation.
authors.affiliation: Department of Molecular Biology & Pharmacology, Washington University School of Medicine, Campus Box 8103, 660 S. Euclid Ave., St. Louis, MO 63110, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Pajewski
authors.forename: Riccardo
authors.initials: R
authors.lastname: Ferdani
authors.forename: Paul H
authors.initials: PH
authors.lastname: Schlesinger
authors.forename: George W
authors.initials: GW
authors.lastname: Gokel
mesh_terms: D000595:Amino Acid Sequence; D002712:Chlorides / Q000737:chemistry*; D002725:Chloroform / Q000737:chemistry; D003903:Deuterium; D005998:Glycine / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry*; D010446:Peptide Fragments / Q000032:analysis; D011392:Proline / Q000737:chemistry; D011485:Protein Binding
chemical_list: D002712:Chlorides; D009842:Oligopeptides; D010446:Peptide Fragments; D002725:Chloroform; D011392:Proline; D003903:Deuterium; D005998:Glycine