title: [Malignant mixed mesodermal tumor: histo- and cytopathologic correlations].
abstract: To correlate the cytopathological and the histopathological findings in uterine mixed mesodermal malignant tumor (MMMT) we have examined the cervical smear, endometrial curettage and hysterectomy specimen of a patient diagnosed with uterine tumor. The smear was stained by Papanicolaou staining and the tissue processed by routine technique and stained H&E. The original cytological diagnosis was adenosquamous carcinoma. The histopathological diagnosis was MMMT of heterologous type. A review of the smear revealed features which may orientate the diagnosis: multinucleate cells, isolated cells with cyanophilic cytoplasm, hyperchromatic nuclei and prominent nucleoli, elongated cyanophilic cells of sarcomatous origin. We conclude that the cytopathological diagnosis of the MMMT in cervical smears is very difficult. This may be sustained by the evidence of more cell types and cellular features orientating to a sarcomatous origin. The most important differential diagnosis is adenosquamous carcinoma.
authors.affiliation: Disciplina Morfopatologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
authors.forename: S
authors.initials: S
authors.lastname: Teleman
authors.forename: Daniela
authors.initials: D
authors.lastname: Scripcaru
authors.forename: Simona
authors.initials: S
authors.lastname: Muscă
authors.forename: Cristina
authors.initials: C
authors.lastname: Anton
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003475:Curettage; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018199:Mixed Tumor, Mesodermal / Q000473:pathology* / Q000601:surgery; D065006:Papanicolaou Test; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery; D014626:Vaginal Smears