Management of the ocular surface and tear film before, during, and after laser in situ keratomileusis.
OBJECTIVE
To identify evidence-based, best practice strategies for managing the ocular surface and tear film before, during, and after laser in situ keratomileusis (LASIK).


METHODS
After a comprehensive review of relevant published literature, evidence-based recommendations for best practice management strategies are presented.


RESULTS
Symptoms of ocular irritation and signs of dysfunction of the integrated lacrimal gland/ocular surface functional gland unit are common before and after LASIK. The status of the ocular surface and tear film before LASIK can impact surgical outcomes in terms of potential complications during and after surgery, refractive outcome, optical quality, patient satisfaction, and the severity and duration of dry eye after LASIK. Before LASIK, the health of the ocular surface should be optimized and patients selected appropriately. Dry eye before surgery and female gender are risk factors for developing chronic dry eye after LASIK. Management of the ocular surface during LASIK can minimize ocular surface damage and the risk of adverse outcomes. Long-term management of the tear film and ocular surface after LASIK can reduce the severity and duration of dry eye symptoms and signs.


CONCLUSIONS
Strategies to manage the integrated ocular surface/lacrimal gland functional unit before, during, and after LASIK can optimize outcomes. As problems with the ocular surface and tear film are relatively common, attention should focus on the use and improvement of evidence-based management strategies.
Albietz
Julie M
JM
Centre for Eye Research, Queensland University of Technology, Brisbane, Australia. julie@darkoptics.com.au
Lenton
Lee M
LM
D003229:Conjunctival Diseases / Q000378:metabolism / Q000628:therapy*; D003316:Corneal Diseases / Q000378:metabolism / Q000628:therapy*; D015352:Dry Eye Syndromes / Q000378:metabolism / Q000517:prevention & control; D019317:Evidence-Based Medicine; D006801:Humans; D007430:Intraoperative Care; D020731:Keratomileusis, Laser In Situ; D011182:Postoperative Care; D017410:Practice Guidelines as Topic; D011300:Preoperative Care; D054140:Refractive Surgical Procedures; D012307:Risk Factors; D013666:Tears / Q000378:metabolism*