Remission of collapsing focal segmental glomerulosclerosis following chemotherapy for myeloma.
Collapsing focal segmental glomerulosclerosis can be idiopathic but has been associated with human immunodeficiency virus infection as well as lymphoproliferative, myeloproliferative, and autoimmune disorders. It has a more rapid progression to end-stage renal failure. Treatment of this condition is poorly defined with no clear evidence of response to any treatment regimens. We report a case of collapsing focal segmental glomerulosclerosis in association with multiple myeloma that underwent partial remission following treatment for the underlying disease.
Shah
Sapna
S
Department of Renal Medicine, Barts and the London NHS Trust, London, UK.
Cavenagh
Jamie
J
Sheaf
Michael
M
Thuraisingham
Raj C
RC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy*; D012074:Remission Induction; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D003907:Dexamethasone; D004317:Doxorubicin