title: Oxygenation of thiolates to S-bonded sulfinate in an iron III complex related to nitrile hydratase.
abstract: Air oxidation of the iron(III) complex derived from (2-mercaptoisobutyryl)-4,5-dichloro-O-phenylenediamine in the presence of Et4NCN afforded the corresponding disulfinato species. With two carboxamido nitrogens trans to two S-bonded sulfinates, this complex mimics the disulfinate inactive form of Fe-NHase.
authors.affiliation: Laboratoire de Chimie et Biochimie Toxicologiques et Pharmacologiques, UMR8601 CNRS, Université René Descartes, 45 rue des St-Pères, 75270 Paris Cedex 06, France.
authors.forename: Erwan
authors.initials: E
authors.lastname: Galardon
authors.forename: Michel
authors.initials: M
authors.lastname: Giorgi
authors.forename: Isabelle
authors.initials: I
authors.lastname: Artaud
mesh_terms: D005290:Ferric Compounds / Q000378:metabolism*; D006836:Hydro-Lyases / Q000378:metabolism*; D008968:Molecular Conformation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013438:Sulfhydryl Compounds / Q000737:chemistry / Q000378:metabolism*; D013440:Sulfides / Q000737:chemistry / Q000378:metabolism*; D013816:Thermodynamics
chemical_list: D005290:Ferric Compounds; D013438:Sulfhydryl Compounds; D013440:Sulfides; D006836:Hydro-Lyases; C048831:nitrile hydratase