title: [Linezolid in two premature babies with necrotizing enterocolitis and infection with vancomycin-resistant enterococcus].
abstract: The use of the antibiotic Linezolid in two premature babies with necrotizing enterocolitis and infection with vancomycin-resistant enterococcus is described. Therapy with Linezolid in cause of necrotizing enterocolitis is an exception. Actually there are no proven recommendations for the use in this age group. Despite the successfully results more investigations for the use of linezolid in newborns and prematures are necessary.
authors.affiliation: Pädiatrische Immunologie und Infektiologie, Interdisziplinäre Kinderintensivmedizin, Kinderklinik der Johannes Gutenberg-Universität Mainz.
authors.forename: U
authors.initials: U
authors.lastname: Klingkowski
authors.forename: R G
authors.initials: RG
authors.lastname: Huth
authors.forename: P
authors.initials: P
authors.lastname: Habermehl
authors.forename: M
authors.initials: M
authors.lastname: Knuf
mesh_terms: D000081:Acetamides / Q000008:administration & dosage* / Q000493:pharmacokinetics; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D018432:Drug Resistance, Multiple; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D016984:Enterococcus faecium / Q000187:drug effects; D020345:Enterocolitis, Necrotizing / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D005865:Gestational Age; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D007081:Ileostomy; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy* / Q000382:microbiology; D007236:Infant, Small for Gestational Age; D007262:Infusions, Intravenous; D007582:Jejunostomy; D000069349:Linezolid; D008297:Male; D008826:Microbial Sensitivity Tests; D023303:Oxazolidinones / Q000008:administration & dosage* / Q000493:pharmacokinetics; D011183:Postoperative Complications / Q000188:drug therapy; D016896:Treatment Outcome; D020713:Vancomycin Resistance
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid