Arterialization of the portal stump by right renal artery after portocaval shunt in the rat.
Portosystemic shunts cause severe secondary effects, so that arterializations of the portal stump are planned to increase the blood supply to the liver. The aim of this study was to verify the technical feasibility of arterialization of the portal stump with the right renal artery in order to obtain a valid experimental model to study the pathophysiology of arterial revascularization of the liver. Twenty rats underwent end-to-side portocaval shunt + end-to-end anastomosis between the right renal artery and portal stump; another 20 rats were subjected to the same surgical procedure, but the portal stump underwent a reduction in size. In our study, both techniques gave good results, but the use of an operating microscope and good microsurgical training were essential in achieving a good patency rate (78.3%).
Li Destri
Giovanni
G
Department of Surgical Sciences, Organ Transplantations, and Advanced Technologies, University of Catania, Catania, Italy.
La Greca
Gaetano
G
Greco
Luigi
L
Greco
Raffaele
R
Licitra
Edelweiss
E
Lanteri
Raffaele
R
Di Cataldo
Antonio
A
D000714:Anastomosis, Surgical; D000818:Animals; D008099:Liver / Q000098:blood supply; D008297:Male; D008866:Microsurgery / Q000379:methods; D011167:Portacaval Shunt, Surgical; D011169:Portal Vein / Q000601:surgery*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012077:Renal Artery / Q000601:surgery*