Angiolymphoid hyperplasia with eosinophilia involving the cubital nerve.
A tumor involving cubital nerve was resected and studied; it was classified as an angiolymphoid hyperplasia with eosinophilia (ALHE). Immunohistochemical and molecular study was done both to confirm the reactive nature of the process and rule out the presence of clonal T or B cell rearrangement. This lesion has been designated as epitheloid hemangioma [Coindre (1994) Ann Pathol 14:426]. Typically, ALHE occurs in the skin and the subcutaneous tissue, and extracutaneous involvement is rare. No cases of ALHE affecting a nerve have been described, but a case of Kimura's disease, the lesions of which have repeatedly been confused with ALHE, has been reported involving median nerve.
Martorell
Miguel
M
Department of Pathology, Hospital General Universitario, Avda Tres Cruces s/n, 46014 Valencia, Spain. miguel-martorell@uv.es
Pérez-Vallés
Ana
A
García-García
Jose Angel
JA
Calabuig
Consuelo
C
Aguilella
Luis
L
D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000378:metabolism* / Q000473:pathology*; D042783:Endothelial Cells / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D019169:Jurkat Cells; D008297:Male; D018807:Polymorphism, Single-Stranded Conformational; D013194:Staining and Labeling / Q000379:methods; D014459:Ulnar Nerve / Q000378:metabolism / Q000473:pathology*