title: Poly-3-hexyl thiophene Langmuir-Blodgett films for application to glucose biosensor.
abstract: Langmuir-Blodgett films of poly(3-hexyl thiophene) have been prepared by simultaneous entrapment of glucose oxidase and transferred onto the indium-tin-oxide coated glass plates. The films have been characterized by FTIR spectroscopy and detailed response studies have been performed with respect to glucose concentration, temperature, and storage time. These P3HT/SA/GOX electrodes have been utilized for glucose estimation from 100-500 mg/dL by amperometric method. The electrodes have been found to have sensitivity of 0.75 nA/mg/dL detection limit of 50 mg/dL and shelf life of about 75 days at 4 degrees C.
authors.affiliation: Biomolecular Electronics & Conducting Polymer Research Group, National Physical Laboratory, Dr. KS Krishnan Road, New Delhi- 110012, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Singhal
authors.forename: Asha
authors.initials: A
authors.lastname: Chaubey
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kaneto
authors.forename: W
authors.initials: W
authors.lastname: Takashima
authors.forename: B D
authors.initials: BD
authors.lastname: Malhotra
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004800:Enzymes, Immobilized; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry*; D005949:Glucose Oxidase / Q000737:chemistry*; D008422:Materials Testing; D008567:Membranes, Artificial; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D020099:Coated Materials, Biocompatible; D004800:Enzymes, Immobilized; D008567:Membranes, Artificial; D011108:Polymers; D013876:Thiophenes; C066730:polythiophene; D005949:Glucose Oxidase; D005947:Glucose