title: Packed red blood cell transfusions in dogs with gastrointestinal hemorrhage: 55 cases (1999-2001).
abstract: Fifty-five dogs received packed red blood cell (PRBC) transfusions for gastrointestinal (GI) hemorrhage during a 26-month period (1999 to 2001), accounting for 11.7% of the PRBC transfusions in that time. Thirty-nine (61%) dogs had an intestinal pathology (primary or secondary) as the cause of GI hemorrhage, including intestinal masses, gastroenteritis, hepatic disease, and renal disease. Nonsteroidal and steroidal anti-inflammatory drug use was found frequently in dogs with GI hemorrhage. Sixteen (39%) dogs were identified as having immune-mediated thrombocytopenia (IMT) and associated GI hemorrhage. Dogs with IMT received more transfusions of PRBC than nonIMT dogs (P<0.03) and received a significantly larger total volume of PRBC (P<0.01) during hospitalization.
authors.affiliation: Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536, USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Waldrop
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Rozanski
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Freeman
authors.forename: John E
authors.initials: JE
authors.lastname: Rush
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D004283:Dog Diseases / Q000139:chemically induced / Q000628:therapy*; D004285:Dogs; D017707:Erythrocyte Transfusion / Q000379:methods / Q000662:veterinary*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000628:therapy / Q000662:veterinary*; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal