title: Effect of lasalocid on growth, blood gases, and nutrient utilization in dairy goats fed a high forage, low protein diet.
abstract: This study investigated the effect of lasalocid on weight gain, blood gases, nutrient digestibility, and nitrogen utilization in growing dairy goats. In a growth experiment, 24 crossbred dairy does were assigned to diets without or with lasalocid (approximately 30 mg per head per day) for 12 wk. Goats were group fed bermudagrass hay for free choice plus concentrate at a fixed level (approximately 0.264 kg DM per head per d). Goats grew faster when fed lasalocid than those fed the control diet. Jugular blood partial pressure of O2 was lower when goats were supplemented with lasalocid. In contrast, goats fed lasalocid tended to have a higher partial pressure of CO2 than control goats. Percent O2 saturation tended to increase, and concentrations of total CO2 tended to decrease in goats fed lasalocid. Serum glucose and urea N did not differ between treatments. In a metabolism experiment, 8 castrated male goats were fed hay and concentrate identical to those of the growth experiment to determine whole tract nutrient digestibility and N utilization. Lasalocid did not affect feed intake or nutrient digestion coefficients. Daily urinary N output was reduced by lasalocid supplementation. In spite of this, N retention was not significantly affected. With use of ionophore, the proportion of urinary N relative to digested N tended to decrease, and the retained N as a proportion of digested N tended to increase.
authors.affiliation: Department of Animal Science, National I-Lan University, I-Lan, Taiwan 260 ROC. cmyang@niu.edu.tw
authors.forename: C M J
authors.initials: CM
authors.lastname: Yang
authors.forename: C T
authors.initials: CT
authors.lastname: Chang
authors.forename: S C
authors.initials: SC
authors.lastname: Huang
authors.forename: T
authors.initials: T
authors.lastname: Chang
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood*; D004032:Diet; D018753:Diet, Protein-Restricted; D004063:Digestion / Q000187:drug effects; D005260:Female; D006041:Goats / Q000502:physiology*; D006128:Growth / Q000187:drug effects*; D007476:Ionophores / Q000494:pharmacology; D007832:Lasalocid / Q000494:pharmacology*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D009919:Orchiectomy; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D015430:Weight Gain / Q000187:drug effects
chemical_list: D007476:Ionophores; D002245:Carbon Dioxide; D009584:Nitrogen; D010100:Oxygen; D007832:Lasalocid