title: Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus.
abstract: Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a fulminant bullous dermatitis. TEN is often a drug-induced reaction and virtually any drug class appears capable of provoking it. We report here a case of TEN after administration of ciprofloxacin. Systemic lupus erythematosus (SLE) was suspected as a possible etiologic or modifying cofactor in TEN in this case.
authors.affiliation: Dept. of Internal Medicine, Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Jongen-Lavrencic
authors.forename: P M
authors.initials: PM
authors.lastname: Schneeberger
authors.forename: J G
authors.initials: JG
authors.lastname: van der Hoeven
mesh_terms: D000328:Adult; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D003131:Combined Modality Therapy; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000188:drug therapy*; D009426:Netherlands; D018570:Risk Assessment; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy
chemical_list: D002939:Ciprofloxacin