[Relation between the prostatic tissue components and natural history, estrogen receptor].
OBJECTIVE
There had been few reports on relations between rates of prostatic tissue components, natural history and estrogen receptor. The present study was performed to evaluate these relations.


METHODS
In this study, we examined 25 patients who had benign prostatic hyperplasia(BPH) and underwent transurethral resection of the prostate(TUR-P) or suprapublic prostatectomy(SPP). According to resection volumes of BPH, patients were divided into four groups; less than 5 g of TUR-P, more than 30 g of TUR-P, less than 70 g of SPP, more than 70 g of SPP. We also examined 13 nonhyperplastic prostates that were obtained from autopsied males. Immunoenzymatic staining and computer image analysis were used to determine the mean rate of the stromal. Additionally, resection volumes of BPH were evaluated according to estrogen receptor staining.


RESULTS
In nonhyperplastic glands, the stromal rates of age 15-40 were almost equal. We found that as resection volumes of BPH increased, the stromal rates were apt to decrease. However, positive rates of estrogen receptor showed no significant difference among the four groups.


CONCLUSIONS
There was a trend of correlation between prostates with a decrease of stromal rate and increase of resection volume. Further studies of large populations are needed to validate this assumption.
Matsuda
Takaharu
T
Department of Pathology, Juntendo University School of Medicine, Bunkyo-Ku, Tokyo 113-8421.
Abe
Hiroshi
H
Suda
Koichi
K
D000368:Aged; D000369:Aged, 80 and over; D003319:Corneal Stroma; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000737:chemistry* / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000378:metabolism* / Q000473:pathology*; D011960:Receptors, Estrogen / Q000032:analysis*
D011960:Receptors, Estrogen