[Sleep disorders in temporal lobe epilepsy].
The objective of this study was to evaluate sleep macrostructure and sleep disturbance in a group of 39 patients with temporal lobe epilepsy (TLE). Patients completed questionnaires to evaluate their sleep and subjective daytime sleepiness (Epworth Sleepiness Scale [ESS]) and undergone Polysomnography and Multiple Sleep Latency Test (MSLT). Daytime sleepiness was the most frequent complaint (85%), followed by wakefulness during sleep, history of seizures during sleep (75%) and initial insomnia (26%). Parasomnias (67%), obstructive sleep apneas (13%), restless legs syndrome (15%) and periodic limb movements (5%) were the most frequent sleep disorders. The most frequent changes of sleep patterns were: sleep architecture fragmentation (100%), decreased amount of REM sleep (92%) and increase in time awake after sleep onset (77%). There were significative correlations between the ESS and the MSLT (p<0,05). In conclusion, TLE patients have fragmented sleep with increased sleep stages shifts, increased number of awakenings and in time awake after sleep onset. REM sleep was decreased. Daytime sleepiness was the most frequent complaint in TLE patients.
de Almeida
Cláudia Angela Vilela
CA
Servi o de Neurologia e Neurocirurgia, Departamento de Neuropsiquiatria, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife PE, Brasil. claudiangela@hotmail.com
Lins
Otávio Gomes
OG
Lins
Salustiano Gomes
SG
Laurentino
Sílvia
S
Valença
Marcelo Moraes
MM
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000927:Anticonvulsants / Q000009:adverse effects; D002940:Circadian Rhythm; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011930:Reaction Time; D017678:Sex Distribution; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D012894:Sleep Stages / Q000187:drug effects / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000503:physiopathology*; D012895:Sleep, REM / Q000502:physiology; D014851:Wakefulness
D000927:Anticonvulsants