Gene Unscrambler for detangling scrambled genes in ciliates.
Scrambled genes are surprisingly common in some species of ciliates. Until now there was no software available to analyze automatically these genes. We present here a program that can automatically align the macronuclear and micronuclear forms of a gene, outputting the location of the macronuclear destined segments and pointer sequences.


BACKGROUND
A web version of the program is available free of charge and can be accessed at http://oxytricha.princeton.edu/GeneUnscrambler.htm
Cavalcanti
Andre R O
AR
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. acavalca@princeton.edu
Landweber
Laura F
LF
D000465:Algorithms; D000818:Animals; D002467:Cell Nucleus / Q000235:genetics*; D002874:Chromosome Mapping / Q000379:methods*; D016798:Ciliophora / Q000235:genetics*; D003196:Computer Graphics; D004252:DNA Mutational Analysis / Q000379:methods; D020869:Gene Expression Profiling / Q000379:methods; D015810:Linkage Disequilibrium; D048631:Micronucleus, Germline / Q000235:genetics; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid; D012984:Software; D014584:User-Computer Interface