title: [Affection of diopters and fundus pathologic changes in high myopic eyes].
abstract: OBJECTIVE
  To investigate the relations of the faulty vision correction caused by high myopia with the increase of diopters and progress of fundus retrograde affection.
  
  
  METHODS
  One hundred and forty cases (280 eyes, diopters are -6.25-30.00) were examined with retinoscopy after undergoing mydriasis. Then the axial length of the anterioposterior diameters was measured with A-wave and B-wave ultrasonography. The fluorescein fundus angiography (FFA) was performed on these eyes. The data were statistically analyzed.
  
  
  RESULTS
  The faulty vision correction of high myopic eyes was obviously decreased with the increase of the diopters. When the visual acuity was -20.00 D, the average correction was clinically lower than 0.42 D. And it could only reach 0.25 D, with the vision being -25.00 D. The difference is very significant (P < 0.001). FFA showed that the pathologic changes of fundus posterior pole appeared with the different degrees of damages, such as simple lesion, diffuse lesion, psoriasis lesion and complex lesion. And the vision correction could be simultaneously influenced by multiple complications. The difference is of significance (P < 0.01).
  
  
  CONCLUSIONS
  Vision correction in high myopic eyes is obviously decreased with the increase of diopters. The higher the diopter is, the harder the vision can be ideally corrected. The greater the pathologic change at the fundus posterior pole, the severer the degree of the damage. The more obvious the visual function is influenced, the harder the vision can be corrected. This paper revealed that high myopia is a kind of complex eye disease. It can be treated not only by lens correction but also by other combined treatments.
authors.affiliation: Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
authors.forename: Rongzhi
authors.initials: R
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000473:pathology*; D012029:Refraction, Ocular; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000209:etiology / Q000473:pathology; D042262:Retinoscopy; D014792:Visual Acuity