[Idiopathic hypereosinophilic syndrome presenting as a single mass in the liver].
Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/mm(3) or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and any case presenting as a large single mass lesion has not been described. Herein we report a case of hypereosinophilic syndrome with hepatic involvement in a 48-year-old woman who presented with a giant single mass. By abdominal CT scan, a lobulated well-margined heterogenous mass lesion was detected in the left lateral segment of the liver. Liver biopsy revealed severe eosinophilic infiltration and centrilobular necrosis of hepatocytes. The lesion completely disappeared after steroid administration for eleven months.
Oh
Kil Chan
KC
Department of Internal Medicine, Hallym University College of Medicine, Anyang, Korea.
Park
Sang Hoon
SH
Baek
Seung Hoon
SH
Park
Chul Hee
CH
Hahn
Tae Ho
TH
Lee
Dong Keun
DK
Yeon
Jong Eun
JE
Kim
Jong Hyeok
JH
Byun
Kwan Soo
KS
Park
Choong Kee
CK
Lee
Chang Hong
CH
D004804:Eosinophils / Q000473:pathology; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis*; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged