title: Primary infantile glaucoma in an Australian population.
abstract: BACKGROUND
  Primary infantile glaucoma presents rarely, but can be responsible for significant visual morbidity. There is little information on the clinical features and visual outcome of a pure population of primary infantile glaucoma, as opposed to a mixed population of primary and secondary glaucoma or combined group of those with trabeculodysgenesis and iridotrabeculodysgenesis.
  
  
  METHODS
  We conducted a retrospective review of children with primary infantile glaucoma seen in south-eastern Australia between 1980 and 2000, using The Royal Children's Hospital ophthalmic diagnostic coding database.
  
  
  RESULTS
  Fifty-one patients with primary infantile glaucoma were identified (83 eyes). This equates to an estimated incidence of approximately 1 in 30,000 births. The mean +/- SD age at presentation was 135 +/- 84 days. 'Burnt-out' disease (megalocornea without raised intraocular pressure) was diagnosed in 10.8%. Goniotomy was the most commonly performed surgical procedure (69.4% of 72 eyes). Surgical success with one or two goniotomies was achieved in 74% of eyes. Visual outcomes at final review were generally good with 61.8% reading 6/12 or better. There were a disproportionately high number of children having a final recorded acuity of <6/60 in the group diagnosed in the first 3 months of life.
  
  
  CONCLUSIONS
  Primary infantile glaucoma is a rare ocular condition in this population that presents at a mean age of 4.4 months. Surgical and visual outcomes are generally favourable.
authors.affiliation: Department of Ophthalmology, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Jane R
authors.initials: JR
authors.lastname: MacKinnon
authors.forename: Antonio
authors.initials: A
authors.lastname: Giubilato
authors.forename: James E
authors.initials: JE
authors.lastname: Elder
authors.forename: Jamie E
authors.initials: JE
authors.lastname: Craig
authors.forename: David A
authors.initials: DA
authors.lastname: Mackey
mesh_terms: D017677:Age Distribution; D001315:Australia / Q000453:epidemiology; D005260:Female; D005901:Glaucoma / Q000151:congenital* / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007429:Intraocular Pressure; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D017678:Sex Distribution; D014129:Trabecular Meshwork / Q000601:surgery; D014792:Visual Acuity