A rapid method for illustrating features in both coding and non-coding regions of a genome.
A bitmap display of the Fourier spectra has been developed which allows convenient whole chromosome scanning for genes and other features. Use of a limited sliding window gives rapid visualization and localization of coding regions in the chromosomes, as well as non-coding features such as repetitive DNA. The method works particularly well on organisms with a skewed base composition, to provide an overview of genomic features.
Hall
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Department of Computer Science and Software Engineering, The University of Melbourne, Victoria 3010, Australia. rshall@cs.mu.oz.au
Stern
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D000465:Algorithms; D000818:Animals; D002874:Chromosome Mapping / Q000379:methods*; D003196:Computer Graphics; D005583:Fourier Analysis; D020869:Gene Expression Profiling / Q000379:methods*; D016678:Genome; D016366:Open Reading Frames / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014584:User-Computer Interface