Transcriptome study in China.
The Chinese genome project was initiated in 1993 with the goal of contributing 1% to the Human Genome Program. The study of gene expression profiles with cDNA microarrays, and large-scale sequencing and analysis of 130928 expressed sequence tags (ESTs), allowed isolation and characterization of over 1000 novel full-length human cDNAs derived from human hematopoietic stem/progenitor cells, neuroendocrine tissues, liver, and cardiovascular cells. In addition, EST sequencing for model organisms, including rat, zebrafish, Schistosoma japonicum and rice was performed, aiming at identifying genes associated with physiological and/or pathological characteristics.
Han
Ze-Guang
ZG
Chinese National Human Genome Center at Shanghai, 250 Bi Bo Road, Zhanjiang High-Tech Park, Pudong, Shanghai 201203, China.
Zhao
Guo-Ping
GP
Chen
Zhu
Z
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000235:genetics; D002681:China; D005821:Genetic Techniques; D015894:Genome, Human; D023281:Genomics; D006410:Hematopoiesis; D016045:Human Genome Project; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000235:genetics; D008113:Liver Neoplasms / Q000235:genetics; D009490:Neurosecretory Systems; D014158:Transcription, Genetic; D014407:Tumor Cells, Cultured