title: Enhancement of the fixation of pyrolytic carbon implants by using atomic oxygen texturing.
abstract: The purpose of this study was to examine the effect on the biocompatibility and biologic fixation of atomic oxygen-textured pyrolytic carbon. The implants consisted of unalloyed pyrolytic carbon rods, with half the length of the rod textured by atomic oxygen, and the other half retaining the as-deposited surface that normally occurs during the manufacturing process. The rods were implanted transcortically across the distal portion of the femurs of 6 adult male rabbits for 8 weeks. The implants were assessed mechanically by measuring the interface strength between the implant and the bone. The implant-bone interface was also examined by light microscopy. No adverse reaction to either the as-deposited or the textured pyrolytic carbon was seen. Percent bone apposition was greater for textured implants than for the as-deposited implants; however, it was not significant. The bone apposition efficiency factor, calculated by dividing the interface strength by the fraction of bone apposition, was greater for the textured implants than for the as-deposited implants. This indicates that the fixation obtained was more effective for the textured implants. The findings of this study suggest that biologic fixation of pyrolytic carbon implants can be enhanced by surface texturing by using direct exposure to atomic oxygen, without compromising its biocompatibility.
authors.affiliation: Ohio College of Podiatric Medicine, Cleveland, OH 44106, USA. vjh@ocpm.edu
authors.forename: Vincent J
authors.initials: VJ
authors.lastname: Hetherington
authors.forename: Jill S
authors.initials: JS
authors.lastname: Kawalec
authors.forename: Bhaskar
authors.initials: B
authors.lastname: Bhattacharyya
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D024803:Biomedical Enhancement; D002244:Carbon; D005269:Femur / Q000601:surgery / Q000637:transplantation; D020007:Implants, Experimental; D008297:Male; D011817:Rabbits; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; C009139:pyrolytic carbon; D002244:Carbon