Aggressive squamous cell carcinoma originating as a Marjolin's ulcer.
BACKGROUND
Marjolin's ulcer is an epidermoid carcinoma arising in a scar or chronic wound and can have an aggressive course.


OBJECTIVE
To present a case of squamous cell carcinoma arising in a burn scar with resulting metastases and to discuss Marjolin's ulcer.


RESULTS
The patient continued to have further metastatic disease despite aggressive surgical treatment.


CONCLUSIONS
In following patients with chronic ulcers and wounds, it is important to evaluate any changes immediately with biopsies and further imaging studies if indicated in order to treat effectively. Even aggressive surgical intervention will sometimes be inadequate in treating these tumors.
Sabin
Shawn R
SR
Dermatology and Skin Cancer Specialists, Kansas City, Missouri, USA.
Goldstein
Glenn
G
Rosenthal
Howard G
HG
Haynes
Kimberly K
KK
D000368:Aged; D002056:Burns / Q000150:complications* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D002921:Cicatrix / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D017169:Neoplasms, Post-Traumatic / Q000209:etiology* / Q000473:pathology* / Q000601:surgery