Translocation of bioactive peptides across cell membranes by carbon nanotubes.
Functionalised carbon nanotubes are able to cross the cell membrane and to accumulate in the cytoplasm or reach the nucleus without being toxic for the cell up to 10 [micro sign]M.
Pantarotto
Davide
D
Institut de Biologie Moléculaire et Cellulaire, UPR9021 CNRS, Strasbourg, France. prato@units.it
Briand
Jean-Paul
JP
Prato
Maurizio
M
Bianco
Alberto
A
D016475:3T3 Cells; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D005434:Flow Cytometry; D051379:Mice; D018613:Microscopy, Confocal; D008856:Microscopy, Fluorescence; D037742:Nanotubes, Carbon / Q000633:toxicity; D010316:Particle Size; D010455:Peptides / Q000378:metabolism*; D021381:Protein Transport
D037742:Nanotubes, Carbon; D010455:Peptides