[Keratoacanthoma: two cases with intravascular spread].
We report two patients with keratoacanthoma, simple in one and multiple in the other, displaying typical histological features except for intravascular spread. Although this spread points to malignancy, it did not allow to rule out the diagnosis of keratoacanthoma. These aggressive histological features, as well as perineural invasion, are not linked to malignant clinical course, according to the literature. Intravascular spread suggests that keratoancanthoma could be considered as a peculiar form of well differentiated squamous cell carcinoma. Comparison between clinical and pathological observations should lead to more specific diagnosis.
Gottfarstein-Maruani
Annabel
A
Service d'Anatomie et de Cytologie Pathologiques, CHR d'Orléans, Hôpital de la Source, BP 6709, 45067 Orléans 2.
Michenet
Patrick
P
Kerdraon
Rémy
R
Bonneau
Carole
C
Heitzmann
Anne
A
Estève
Eric
E
Rémy
Roger-Claude
RC
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D007636:Keratoacanthoma / Q000473:pathology* / Q000601:surgery; D008297:Male; D009361:Neoplasm Invasiveness; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
D007633:Keratins