title: Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy.
authors.forename: N M L
authors.initials: NM
authors.lastname: Veldhorst-Janssen
authors.forename: H H
authors.initials: HH
authors.lastname: Boersma
authors.forename: M C T F M
authors.initials: MC
authors.lastname: de Krom
authors.forename: R E N
authors.initials: RE
authors.lastname: van Rijswijk
mesh_terms: D000284:Administration, Oral; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology* / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy; D004347:Drug Interactions; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D002955:Leucovorin / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000188:drug therapy; D005641:Tegafur / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D000964:Antimetabolites, Antineoplastic; D005641:Tegafur; D010672:Phenytoin; D002955:Leucovorin