Internodal myelinated segments: delay and RGC time-domain Green function model.
The myelinated axon can be modeled by means of a distributed RGC circuit. The Green function of this model allows for a generic formulation of the internodal segment response to any kind of stimulus, and accounts for the delay of the action potential associated with this segment. The RGC model accuracy is comparable to that of a more complex electromagnetic model, and predicted delay agrees with experimental measurements.
Villapecellín-Cid
Manuel María
MM
Grupo de Ingeniería Biomédica, Escuela Superior de Ingeniería, University of Seville, Avda. de los Descubrimientos s/n, 41092, Seville, Spain. mavilla@ieee.org
Medina
Francisco
F
Roa
Laura María
LM
D000200:Action Potentials / Q000502:physiology*; D003198:Computer Simulation; D025802:Electric Capacitance; D004553:Electric Conductivity; D017097:Electric Impedance; D008564:Membrane Potentials / Q000502:physiology*; D008959:Models, Neurological; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D009431:Neural Conduction / Q000502:physiology*; D011901:Ranvier's Nodes / Q000502:physiology; D013997:Time Factors