Loss of left bundle branch block following biventricular pacing therapy for heart failure: evidence for electrical remodeling?
Cardiac resynchronization therapy has been proven to improve symptoms and indices of left ventricular function in patients with heart failure and intraventricular conduction delays. We present a case of a patient with New York Association Class III heart failure and left bundle branch block, who received a biventricular pacemaker in order to achieve cardiac resynchronization. Her symptoms improved markedly, as did left ventricular ejection fraction and dimensions. In addition, her intrinsic QRS duration normalized. This may represent a salutory effect of biventricular pacing on electrical remodeling.
Dizon
José
J
Department of Medicine, Division of Cardiology, Columbia-Presbyterian Medical Center, Columbia University, New York, USA. JMD11@Columbia.edu
Horn
Evelyn
E
Neglia
John
J
Medina
Norma
N
Garan
Hasan
H
D002037:Bundle-Branch Block / Q000150:complications / Q000503:physiopathology*; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D010138:Pacemaker, Artificial; D013318:Stroke Volume; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling