Biocompatibility of a flowable composite bonded with a self-etching adhesive compared with a glass lonomer cement and a high copper amalgam.
This study evaluated the pulpal response and in-vivo microleakage of a flowable composite bonded with a self-etching adhesive and compared the results with a glass ionomer cement and amalgam. Cervical cavities were prepared in monkey teeth. The teeth were randomly divided into three groups. A self-etching primer system (Imperva FluoroBond, Shofu) was applied to the teeth in one of the experimental groups, and the cavities were filled with a flowable composite (SI-BF-2001-LF, Shofu). In the other groups, a glass ionomer cement (Fuji II, GC) or amalgam (Dispersalloy, Johnson & Johnson) filled the cavity. The teeth were then extracted after 3, 30 and 90 days, fixed in 10% buffered formalin solution and prepared according to routine histological techniques. Five micrometer sections were stained with hematoxylin and eosin or Brown and Brenn gram stain for bacterial observation. No serious inflammatory reaction of the pulp, such as necrosis or abscess formation, was observed in any of the experimental groups. Slight inflammatory cell infiltration was the main initial reaction, while deposition of reparative dentin was the major long-term reaction in all groups. No bacterial penetration along the cavity walls was detected in the flowable composite or glass ionomer cement except for one case at 30 days in the glass ionomer cement. The flowable composite bonded with self-etching adhesive showed an acceptable biological com- patibility to monkey pulp. The in vivo sealing ability of the flowable composite in combination with the self-etching adhesive was considered comparable to glass ionomer cement. Amalgam restorations without adhesive liners showed slight bacterial penetration along the cavity wall.
Shimada
Yasushi
Y
Graduate School, Tokyo Medical and Dental University, Tokyo, Japan. shimada.ope@tmd.ac.jp
Seki
Yuichi
Y
Sasafuchi
Yasutaka
Y
Arakawa
Makoto
M
Burrow
Michael F
MF
Otsuki
Masayuki
M
Tagami
Junji
J
D000704:Analysis of Variance; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D003722:Dental Alloys / Q000737:chemistry; D003723:Dental Amalgam / Q000737:chemistry*; D001840:Dental Bonding; D045662:Dental Etching; D003763:Dental Leakage / Q000145:classification / Q000382:microbiology; D003782:Dental Pulp / Q000473:pathology; D003809:Dentin, Secondary / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D008251:Macaca; D008422:Materials Testing; D011897:Random Allocation; D013997:Time Factors
D001672:Biocompatible Materials; D003188:Composite Resins; D003722:Dental Alloys; D017220:Dentin-Bonding Agents; D005899:Glass Ionomer Cements; C111840:flowable hybrid composite; C474103:imperva fluoro bond; C084541:Fuji glass-ionomer lining cement; C033470:Dispersalloy; D003300:Copper; D003723:Dental Amalgam