title: Experience with primary laparoscopy-assisted endorectal pull-through for Hirschsprung's disease.
abstract: From October 1996 to July 2001, 61 patients received primary laparoscopy-assisted endorectal pull-through (LAERPT) for biopsy-proven Hirschsprung's disease (HD) at Mackay Memorial Hospital. The patients' ages at operation ranged from 7 days to 8 years. The patients were followed up for an average of 3.8 years (range 1-5.5 years). Major complications occurred in five (8.1%) patients, of whom four had surgical complications (two instances of anastomotic leakage, one colon perforation, and one delayed formation of colovesical fistula) and one had postoperative Salmonella infection-induced colonic stricture. The five patients required a diverting colostomy and a redo-pull-through procedure. Postoperative enterocolitis developed in 13 (21%) infants. All of them had enterocolitis before the diagnosis of HD was established. The majority of the episodes of postoperative enterocolitis were mild and resolved spontaneously, but four neonates were hospitalized with significant systemic manifestations, and two of them needed a second operation to solve the problem. After primary LAERPT, stooling frequency in young infants declined rapidly from 10.5+/-3.2 to 4.4+/-1.6 bowel movements per day in the first 3 months and more slowly thereafter. Most of these infants had regular bowel movements one to two times per day 1 year after operation. Continence evaluation of the 43 patients over 3 years of age was graded as normal in 24 (56%) patients and good in 19 (44%) patients. Of the 13 patients between 1 and 3 years of age, 11 (85%) had regular normal stools, and two (15%) had occasional soiling. From the current study, the authors concluded that primary LAERPT is a safe and effective method of managing HD with excellent continence results. Considering the complications of surgery and postoperative enterocolitis, patients with long segment aganglionosis, severe enterocolitis, or prominently dilated colon are not good candidates for primary LAERPT.
authors.affiliation: Department of Pediatric Surgery, Mackay Memorial Hospital, 92, Section 2, Chung-San North Rd., 10449, Taipei, Taiwan, Republic of China. nien4819@ms9.hinet.net
authors.forename: Nien-Lu
authors.initials: NL
authors.lastname: Wang
authors.forename: Hung-Chang
authors.initials: HC
authors.lastname: Lee
authors.forename: Ming-Lun
authors.initials: ML
authors.lastname: Yeh
authors.forename: Pei-Yeh
authors.initials: PY
authors.lastname: Chang
authors.forename: Jin-Cherng
authors.initials: JC
authors.lastname: Sheu
mesh_terms: D000714:Anastomosis, Surgical; D002648:Child; D002675:Child, Preschool; D003082:Colectomy / Q000379:methods*; D005260:Female; D006627:Hirschsprung Disease / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010535:Laparoscopy; D008297:Male; D011183:Postoperative Complications