title: Keloidal scleroderma.
abstract: Progressive systemic sclerosis (PSS) can involve the skin diffusely or in a limited way. Rarely cutaneous involvement can assume a hypertrophic form, described in the literature as keloidal scleroderma. The authors describe a PSS patient who presented cutaneous manifestations compatible with the diagnosis of this clinical situation. The clinical features, pathogenic mechanism and therapeutic approach are discussed and a broad review of the literature is given.
authors.affiliation: Escola Bahiana de Medicina e Saúde Pública, Bahia, Brazil. mitter@svn.com.br
authors.forename: Mittermayer
authors.initials: M
authors.lastname: Santiago
authors.forename: Dálvaro Oliveira
authors.initials: DO
authors.lastname: de Castro
authors.forename: Cíntia Andrade
authors.initials: CA
authors.lastname: Costa
authors.forename: Edgard Souza
authors.initials: ES
authors.lastname: Passos
authors.forename: Ariene
authors.initials: A
authors.lastname: Paixão
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007627:Keloid / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D010396:Penicillamine / Q000627:therapeutic use; D045743:Scleroderma, Diffuse / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D010396:Penicillamine; D001379:Azathioprine