title: Antimicrobial activity of Hyptis ovalifolia towards dermatophytes.
abstract: The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of   500  g/ml.
authors.affiliation: Laboratório de Micologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, GO, Brasil. lucki@persogo.com.br
authors.forename: Lúcia K H
authors.initials: LK
authors.lastname: Souza
authors.forename: Cecília M A
authors.initials: CM
authors.lastname: de Oliveira
authors.forename: Pedro H
authors.initials: PH
authors.lastname: Ferri
authors.forename: Juldásio Galdino
authors.initials: JG
authors.lastname: de Oliveira Júnior
authors.forename: Ary Henrique
authors.initials: AH
authors.lastname: de Souza Júnior
authors.forename: Orionalda de Fátima Lisboa
authors.initials: Ode F
authors.lastname: Fernandes
authors.forename: Maria do Rosário R
authors.initials: Mdo R
authors.lastname: Silva
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000145:classification / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D031331:Hyptis; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts