title: [Pancreatic insulinomas: diagnosis and treatment].
abstract: BACKGROUND
  Despite its rarity, the insulinoma is the most common pancreatic neuroendocrine tumor.
  
  
  OBJECTIVE
  Analyze clinical and immunohistochemical data from surgical resection of the pancreas insulinoma.
  
  
  METHODS
  Twelve cases are described, concerning surgical aspects, complications and medium-long term outcome of patients. They underwent surgical treatment due to clinical suspicion and biochemical diagnosis of hypoglycemia and hyperinsulinism.
  
  
  RESULTS
  The insulinoma was identified preoperatively in seven patients, while intraoperative ultrasonography and palpation were necessary for diagnosis in the other cases. Eight patients underwent pancreatic resection and pancreatic leak was observed in seven cases. Two patients developed diabetes mellitus and no mortality occurred in the current series.
  
  
  CONCLUSIONS
  All patients presented satisfactory outcome and remained asymptomatic with normal glicemia levels.
authors.affiliation: Disciplina de Grastroenterologia Cirúrgica do Departamento de Cirurgia da Universitade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brasil. apodaca@uol.com.br
authors.forename: Franz Robert
authors.initials: FR
authors.lastname: Apodaca-Torrez
authors.forename: Tarcisio
authors.initials: T
authors.lastname: Triviño
authors.forename: Edson José
authors.initials: EJ
authors.lastname: Lobo
authors.forename: Alberto
authors.initials: A
authors.lastname: Goldenberg
authors.forename: Antônio
authors.initials: A
authors.lastname: Figueira
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007340:Insulinoma / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010185:Pancreatic Fistula / Q000209:etiology; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery*
chemical_list: D001786:Blood Glucose